# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- PHO4 PF01384.20 EPS25071.1 - 1.3e-110 369.6 10.4 1.5e-110 369.4 10.4 1.0 1 0 0 1 1 1 1 Phosphate transporter family EcsC PF12787.7 EPS25071.1 - 0.21 11.2 0.1 0.43 10.2 0.1 1.5 1 0 0 1 1 1 0 EcsC protein family GFA PF04828.14 EPS25072.1 - 6.6e-11 42.4 0.8 1.3e-10 41.4 0.8 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme CBM-like PF14683.6 EPS25073.1 - 4.6e-25 88.4 0.0 9.2e-25 87.4 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 EPS25073.1 - 1.3e-22 79.3 0.1 3.7e-22 77.9 0.1 1.8 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 EPS25073.1 - 0.011 15.9 0.1 0.037 14.3 0.0 2.0 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain Peptidase_S10 PF00450.22 EPS25074.1 - 3.6e-77 260.5 0.0 4.8e-77 260.1 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase CdiI_4 PF18624.1 EPS25074.1 - 0.097 13.2 1.0 0.16 12.4 0.3 1.9 2 0 0 2 2 2 0 CDI immunity protein Acetyltransf_3 PF13302.7 EPS25075.1 - 3.4e-29 102.3 0.0 4.1e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPS25075.1 - 0.0029 17.8 0.0 0.015 15.5 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family CRAL_TRIO PF00650.20 EPS25076.1 - 7.5e-45 152.5 0.0 1.4e-44 151.6 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EPS25076.1 - 8.3e-11 41.9 0.0 2.2e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EPS25076.1 - 1.2e-06 28.7 0.0 1.9e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DHQ_synthase PF01761.20 EPS25077.1 - 1.2e-51 175.4 0.0 1.8e-51 174.9 0.0 1.2 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 EPS25077.1 - 2.7e-13 50.2 0.0 4.4e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 EPS25077.1 - 0.00099 18.0 0.0 0.0017 17.3 0.0 1.5 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Methyltransf_3 PF01596.17 EPS25078.1 - 1.2e-15 57.3 0.0 1.5e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EPS25078.1 - 3.1e-11 44.3 0.0 5e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.12 EPS25078.1 - 0.01 15.5 0.0 0.016 14.9 0.0 1.5 1 1 0 1 1 1 0 Cephalosporin hydroxylase MFS_1 PF07690.16 EPS25080.1 - 3.4e-20 72.3 40.8 4.9e-15 55.3 21.5 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS25080.1 - 2e-19 69.8 20.8 7.4e-19 67.9 20.8 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter FAD_binding_4 PF01565.23 EPS25082.1 - 3.5e-25 88.4 0.5 7.1e-24 84.1 0.2 2.4 2 0 0 2 2 2 1 FAD binding domain LytR_C PF13399.6 EPS25082.1 - 0.0083 17.1 0.1 0.021 15.8 0.1 1.7 1 0 0 1 1 1 1 LytR cell envelope-related transcriptional attenuator BBE PF08031.12 EPS25082.1 - 0.014 15.5 0.0 0.033 14.3 0.0 1.7 1 0 0 1 1 1 0 Berberine and berberine like Glyco_hydr_30_2 PF14587.6 EPS25083.1 - 9e-13 48.5 0.5 1.6e-07 31.2 0.0 3.0 2 1 1 3 3 3 3 O-Glycosyl hydrolase family 30 CBM_1 PF00734.18 EPS25083.1 - 1.3e-12 47.4 13.2 1.3e-12 47.4 13.2 2.7 2 0 0 2 2 2 1 Fungal cellulose binding domain Glyco_hydro_30C PF17189.4 EPS25083.1 - 2.1e-12 47.1 4.1 1.2e-11 44.6 4.1 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 EPS25083.1 - 4.3e-12 45.9 0.2 6.5e-12 45.3 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_30 PF02055.16 EPS25083.1 - 2.6e-07 30.0 1.3 4.7e-07 29.1 0.1 1.9 3 0 0 3 3 3 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_43 PF04616.14 EPS25084.1 - 3.7e-35 121.6 4.3 5.5e-35 121.1 4.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 EPS25084.1 - 4.5e-24 85.3 0.1 6.6e-24 84.8 0.1 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain CBM_1 PF00734.18 EPS25084.1 - 3.8e-12 45.9 12.2 1.2e-11 44.4 12.2 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_62 PF03664.13 EPS25085.1 - 8.1e-138 458.3 9.4 1.1e-137 457.9 9.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 CBM_1 PF00734.18 EPS25085.1 - 8e-12 44.9 12.9 2.5e-11 43.3 12.9 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Fungal_trans_2 PF11951.8 EPS25086.1 - 6.4e-11 41.7 0.3 8.9e-11 41.2 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS25086.1 - 0.76 10.0 9.7 1.7 8.8 9.7 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Arylesterase PF01731.20 EPS25087.1 - 0.12 12.6 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 Arylesterase Ppx-GppA PF02541.16 EPS25088.1 - 1.6e-40 139.4 0.0 3.6e-40 138.2 0.0 1.5 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Hydrophobin PF01185.18 EPS25090.1 - 2.6e-07 31.2 8.3 4.5e-07 30.4 8.3 1.4 1 0 0 1 1 1 1 Fungal hydrophobin DUF2574 PF10836.8 EPS25090.1 - 0.031 14.1 1.5 0.042 13.7 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2574) AMP-binding PF00501.28 EPS25091.1 - 2.9e-105 352.3 0.0 3.4e-105 352.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EPS25091.1 - 1.4e-13 51.6 0.0 3.2e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pyr_redox_2 PF07992.14 EPS25092.1 - 7.1e-28 97.7 0.0 1e-27 97.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPS25092.1 - 1.9e-15 57.2 0.0 2.7e-13 50.3 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EPS25092.1 - 0.00083 19.0 1.0 0.14 11.8 0.2 3.3 4 0 0 4 4 4 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 EPS25092.1 - 0.0031 16.7 0.0 0.0057 15.8 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EPS25092.1 - 0.0035 16.6 0.0 0.14 11.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EPS25092.1 - 0.0057 15.7 0.1 0.0092 15.1 0.1 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein NaeI PF09126.10 EPS25092.1 - 0.062 12.5 0.0 0.11 11.7 0.0 1.4 1 1 0 1 1 1 0 Restriction endonuclease NaeI AlaDh_PNT_C PF01262.21 EPS25092.1 - 0.13 11.5 0.0 1.5 8.1 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GST_N PF02798.20 EPS25095.1 - 5.2e-13 49.1 0.0 8.6e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EPS25095.1 - 4e-11 43.0 0.0 5.6e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EPS25095.1 - 5.4e-09 36.3 0.0 1.1e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EPS25095.1 - 6.8e-07 29.2 0.0 1.7e-06 28.0 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EPS25095.1 - 2.4e-06 27.7 0.0 4.6e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EPS25095.1 - 0.00036 20.8 0.0 0.00057 20.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 EPS25095.1 - 0.075 13.8 0.0 0.14 13.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain GMC_oxred_N PF00732.19 EPS25096.1 - 2.7e-48 164.9 0.5 3.7e-48 164.4 0.5 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EPS25096.1 - 2.3e-33 115.8 0.1 2.3e-32 112.5 0.0 2.3 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EPS25096.1 - 2.8e-06 26.7 0.1 5.8e-06 25.7 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 EPS25096.1 - 1.2e-05 24.7 0.0 2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EPS25096.1 - 3.7e-05 23.1 0.2 7.6e-05 22.1 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EPS25096.1 - 0.00011 21.9 0.3 0.0013 18.4 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EPS25096.1 - 0.00016 21.9 1.6 0.00075 19.7 0.4 2.7 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EPS25096.1 - 0.0019 17.5 0.1 0.0037 16.5 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 EPS25096.1 - 0.0053 16.2 1.1 0.01 15.2 0.4 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EPS25096.1 - 0.016 13.9 0.1 0.032 12.9 0.1 1.5 1 0 0 1 1 1 0 HI0933-like protein ThiF PF00899.21 EPS25096.1 - 0.06 12.7 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 ThiF family Lycopene_cycl PF05834.12 EPS25096.1 - 0.12 11.4 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 EPS25096.1 - 0.21 10.7 0.1 0.6 9.1 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A BTB_2 PF02214.22 EPS25097.1 - 1.7e-08 34.7 0.4 7.8e-05 23.0 0.1 2.4 2 0 0 2 2 2 2 BTB/POZ domain BTB PF00651.31 EPS25097.1 - 0.2 11.9 0.0 28 5.0 0.0 2.4 2 0 0 2 2 2 0 BTB/POZ domain Methyltr_RsmB-F PF01189.17 EPS25098.1 - 9.4e-14 51.5 0.1 5.5e-07 29.4 0.1 3.2 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F Acetyltransf_1 PF00583.25 EPS25099.1 - 1.1e-07 32.0 0.0 2e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EPS25099.1 - 3.2e-07 30.3 0.0 0.0052 16.7 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EPS25099.1 - 5.9e-06 26.6 0.0 2.4e-05 24.7 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EPS25099.1 - 2.6e-05 24.3 0.0 5.4e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_5 PF13444.6 EPS25099.1 - 0.0087 16.8 0.0 0.093 13.5 0.0 2.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPS25099.1 - 0.045 13.7 0.0 0.11 12.5 0.0 1.6 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_9 PF13527.7 EPS25099.1 - 0.054 13.6 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Bac_rhamnosid_C PF17390.2 EPS25099.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase C-terminal domain Lysis_col PF02402.16 EPS25100.1 - 0.14 11.8 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Lysis protein FYVE PF01363.21 EPS25101.1 - 3.1e-15 56.0 7.4 4.7e-15 55.5 7.4 1.3 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.16 EPS25101.1 - 0.2 11.8 10.7 0.41 10.9 10.7 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger IBR PF01485.21 EPS25101.1 - 1.3 9.3 7.5 0.099 12.9 2.6 1.6 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain 2-Hacid_dh_C PF02826.19 EPS25104.1 - 9.6e-54 181.4 0.0 1.3e-53 181.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EPS25104.1 - 1.7e-28 99.0 0.0 2e-28 98.7 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AlaDh_PNT_C PF01262.21 EPS25104.1 - 0.0031 16.9 1.4 0.25 10.6 1.4 2.3 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.21 EPS25104.1 - 0.0037 17.4 0.1 0.023 14.7 0.0 2.0 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 EPS25104.1 - 0.011 15.9 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.6 EPS25104.1 - 0.15 12.6 0.1 3.8 8.0 0.0 2.5 2 0 0 2 2 2 0 XdhC Rossmann domain Glycos_transf_1 PF00534.20 EPS25105.1 - 1.4e-34 119.1 0.0 2.1e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EPS25105.1 - 1.3e-28 100.1 0.0 2e-28 99.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EPS25105.1 - 8e-13 48.7 0.7 4.9e-12 46.2 0.0 2.4 3 0 0 3 3 3 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EPS25105.1 - 3.7e-11 43.7 5.8 4.1e-11 43.6 0.0 2.6 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EPS25105.1 - 1.5e-07 31.7 0.0 3.3e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 CPSF73-100_C PF11718.8 EPS25105.1 - 0.19 11.2 0.0 0.28 10.7 0.0 1.2 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term ECH_1 PF00378.20 EPS25107.1 - 5.3e-46 157.0 0.0 6.9e-46 156.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EPS25107.1 - 5.2e-29 101.8 0.5 3.8e-24 85.8 0.2 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase GST_N PF02798.20 EPS25108.1 - 5.1e-15 55.6 0.3 1.2e-14 54.4 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EPS25108.1 - 4.1e-10 39.8 0.0 7.4e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EPS25108.1 - 7.8e-10 39.0 0.1 1.8e-09 37.9 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EPS25108.1 - 1.8e-07 31.2 0.0 3.3e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EPS25108.1 - 4.9e-06 26.7 0.0 8.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EPS25108.1 - 7.8e-06 25.8 0.0 2e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EPS25108.1 - 0.0025 18.4 0.0 0.0054 17.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NDUF_B4 PF07225.12 EPS25109.1 - 1.6e-05 24.8 0.0 1.8e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) DUF3649 PF12365.8 EPS25109.1 - 0.0022 17.6 1.3 0.0031 17.2 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3649) SAP18 PF06487.12 EPS25110.1 - 1.5e-48 164.5 0.0 1.8e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Prp18 PF02840.15 EPS25111.1 - 3.7e-56 189.1 0.1 3.7e-56 189.1 0.1 2.6 2 1 1 3 3 3 1 Prp18 domain PRP4 PF08799.11 EPS25111.1 - 2.3e-10 39.8 6.6 2.3e-10 39.8 6.6 2.7 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like AF-4 PF05110.13 EPS25111.1 - 0.033 12.3 19.4 0.043 11.9 19.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein CDC27 PF09507.10 EPS25111.1 - 0.87 8.9 32.9 1.3 8.3 32.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 V_ATPase_I PF01496.19 EPS25111.1 - 2.2 6.1 12.6 3.4 5.5 12.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SOBP PF15279.6 EPS25111.1 - 4.2 7.9 6.5 6.9 7.2 6.5 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Polysacc_deac_1 PF01522.21 EPS25112.1 - 7.5e-17 61.4 0.0 1e-16 60.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_2 PF04748.13 EPS25112.1 - 0.12 11.6 0.0 0.23 10.6 0.0 1.5 1 1 0 1 1 1 0 Divergent polysaccharide deacetylase COA2 PF17051.5 EPS25113.1 - 0.057 13.5 0.1 0.2 11.8 0.1 1.9 2 0 0 2 2 2 0 Cytochrome C oxidase assembly factor 2 K_oxygenase PF13434.6 EPS25113.1 - 0.17 11.0 0.1 3.3 6.8 0.0 2.8 3 1 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Arf PF00025.21 EPS25114.1 - 9e-40 136.0 0.0 2.1e-26 92.4 0.0 2.3 2 1 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.20 EPS25114.1 - 2.8e-15 56.3 0.0 4.9e-09 35.8 0.0 2.1 2 0 0 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EPS25114.1 - 2.2e-10 40.8 0.0 6.9e-10 39.2 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 EPS25114.1 - 1e-06 28.3 0.0 1.6e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EPS25114.1 - 2e-06 27.9 0.0 4.2e-06 26.8 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 EPS25114.1 - 2.8e-06 27.0 0.0 0.0008 19.0 0.0 2.6 2 1 0 2 2 2 2 Ras family SRPRB PF09439.10 EPS25114.1 - 2.9e-06 26.9 0.0 1.9e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EPS25114.1 - 0.0062 16.1 0.0 0.16 11.5 0.0 2.3 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EPS25114.1 - 0.048 13.2 0.1 0.1 12.1 0.1 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B TniB PF05621.11 EPS25114.1 - 0.074 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein PIGA PF08288.12 EPS25116.1 - 1.2e-45 154.1 3.7 1.3e-45 153.9 1.2 2.1 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 EPS25116.1 - 2e-27 96.3 0.2 3.6e-27 95.4 0.2 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 EPS25116.1 - 8.5e-27 93.8 0.0 1.3e-26 93.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EPS25116.1 - 9.1e-24 84.4 0.1 1.8e-23 83.4 0.1 1.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EPS25116.1 - 2.2e-11 44.5 0.0 4e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EPS25116.1 - 0.00037 20.8 0.0 0.01 16.2 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.6 EPS25116.1 - 0.001 19.1 0.1 0.0021 18.1 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like Asparaginase_C PF17763.1 EPS25116.1 - 0.14 12.4 0.0 14 5.9 0.0 2.5 2 0 0 2 2 2 0 Glutaminase/Asparaginase C-terminal domain DEAD PF00270.29 EPS25117.1 - 4.9e-35 120.9 0.0 9.4e-17 61.3 0.0 2.8 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.31 EPS25117.1 - 1.1e-19 70.9 0.0 3.1e-19 69.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPS25117.1 - 9.8e-08 32.2 0.0 1.7e-06 28.1 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit SDA1 PF05285.12 EPS25117.1 - 0.0016 18.0 10.1 0.0016 18.0 10.1 2.4 2 1 0 2 2 2 1 SDA1 DDHD PF02862.17 EPS25117.1 - 0.038 14.2 9.7 1.2 9.2 0.4 2.6 2 0 0 2 2 2 0 DDHD domain Raftlin PF15250.6 EPS25117.1 - 4.9 5.8 24.1 0.073 11.8 1.8 2.1 2 0 0 2 2 2 0 Raftlin Nop14 PF04147.12 EPS25117.1 - 9 4.4 40.9 0.0056 15.0 12.3 2.1 2 0 0 2 2 2 0 Nop14-like family Glyco_hydro_3_C PF01915.22 EPS25118.1 - 1.7e-50 171.9 0.1 2.7e-50 171.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EPS25118.1 - 1.4e-30 106.7 0.0 2.4e-30 106.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EPS25118.1 - 1.7e-07 31.2 0.0 3.3e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DDR PF08841.10 EPS25118.1 - 0.062 12.3 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Glyco_hydro_76 PF03663.14 EPS25120.1 - 3e-145 484.4 10.2 3.5e-145 484.1 10.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EPS25120.1 - 0.14 11.2 9.1 0.31 10.1 0.3 2.9 3 0 0 3 3 3 0 Glycosyl Hydrolase Family 88 Fungal_trans PF04082.18 EPS25121.1 - 8.2e-15 54.5 0.1 1.5e-14 53.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS25121.1 - 2.9e-10 40.1 11.3 5e-10 39.3 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TCTP PF00838.17 EPS25122.1 - 3.1e-57 193.5 0.4 3.5e-57 193.4 0.4 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein FA_hydroxylase PF04116.13 EPS25123.1 - 2.8e-23 82.7 12.2 2.8e-23 82.7 12.2 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily XFP_C PF09363.10 EPS25123.1 - 0.0027 17.2 0.0 0.0045 16.5 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain MOSC PF03473.17 EPS25125.1 - 1.3e-23 83.4 0.0 2.8e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 MOSC domain Fer2 PF00111.27 EPS25125.1 - 1.6e-12 47.2 0.9 3.8e-12 46.0 0.5 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain 3-alpha PF03475.14 EPS25125.1 - 7.1e-07 29.0 0.1 1.9e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 3-alpha domain NAD_binding_6 PF08030.12 EPS25125.1 - 0.0011 19.1 0.0 0.0024 18.0 0.0 1.7 1 0 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 EPS25125.1 - 0.012 16.3 0.1 0.22 12.2 0.1 2.6 2 1 0 2 2 2 0 Oxidoreductase NAD-binding domain Phage_holin_3_6 PF07332.11 EPS25127.1 - 0.0099 15.9 0.7 0.017 15.2 0.7 1.3 1 0 0 1 1 1 1 Putative Actinobacterial Holin-X, holin superfamily III SRP19 PF01922.17 EPS25128.1 - 4.3e-34 117.3 0.0 6.5e-34 116.8 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein Aminotran_3 PF00202.21 EPS25129.1 - 1.1e-93 314.1 0.0 1.5e-93 313.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III V_ATPase_prox PF18274.1 EPS25129.1 - 0.03 14.3 0.1 0.093 12.7 0.1 1.8 1 0 0 1 1 1 0 Vacuolar ATPase Subunit I N-terminal proximal lobe CPSF73-100_C PF11718.8 EPS25130.1 - 1.1e-84 283.4 0.2 1.5e-84 282.9 0.2 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 EPS25130.1 - 1.4e-29 102.6 0.0 2.8e-29 101.6 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 EPS25130.1 - 3.4e-22 79.4 0.8 8.8e-22 78.1 0.0 2.1 3 0 0 3 3 3 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 EPS25130.1 - 4e-15 55.8 0.0 6.3e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 EPS25130.1 - 1.1e-11 44.4 0.0 2.3e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 EPS25130.1 - 3.9e-05 23.3 0.1 9.1e-05 22.1 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EPS25130.1 - 0.00064 19.6 0.0 0.0023 17.9 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain TAF4 PF05236.14 EPS25131.1 - 1.6e-30 106.9 0.8 1.3e-23 84.2 0.5 2.3 2 0 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family Pkinase PF00069.25 EPS25132.1 - 1.2e-49 169.0 0.0 7.1e-49 166.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS25132.1 - 6.5e-19 68.2 0.0 1.8e-18 66.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Amidase PF01425.21 EPS25134.1 - 6.9e-77 259.3 1.5 8.2e-70 236.0 1.2 2.4 2 1 0 2 2 2 2 Amidase Mtc PF03820.17 EPS25135.1 - 4.5e-120 400.4 0.0 5.1e-120 400.2 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier MgpC PF05220.12 EPS25135.1 - 0.063 12.6 0.1 0.091 12.1 0.1 1.2 1 0 0 1 1 1 0 MgpC protein precursor PHD PF00628.29 EPS25136.1 - 4.7e-08 32.8 8.0 7.8e-08 32.1 8.0 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EPS25136.1 - 0.23 11.0 4.7 0.41 10.2 4.7 1.4 1 0 0 1 1 1 0 PHD-finger DUF2293 PF10056.9 EPS25138.1 - 1.7e-29 101.9 0.0 3.5e-29 100.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) Gly_transf_sug PF04488.15 EPS25139.1 - 4.8e-12 46.4 0.0 1.1e-11 45.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 EPS25139.1 - 0.14 11.4 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.12 EPS25139.1 - 0.16 11.4 0.1 0.45 9.9 0.0 1.7 2 0 0 2 2 2 0 Capsular polysaccharide synthesis protein TruD PF01142.18 EPS25140.1 - 2.3e-62 211.2 0.2 4.5e-58 197.0 0.1 3.1 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) DUF4448 PF14610.6 EPS25141.1 - 0.00015 21.6 0.0 0.00025 20.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) SKG6 PF08693.10 EPS25141.1 - 0.0011 18.3 2.2 0.0011 18.3 2.2 1.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Gram_pos_anchor PF00746.21 EPS25141.1 - 0.014 15.3 1.2 0.028 14.3 1.2 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DUF3188 PF11384.8 EPS25141.1 - 0.11 12.2 1.1 0.2 11.4 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) TMEM154 PF15102.6 EPS25141.1 - 0.66 9.9 2.3 0.82 9.6 0.1 2.3 2 1 0 2 2 2 0 TMEM154 protein family AIM3 PF17096.5 EPS25142.1 - 0.00084 20.2 0.4 0.00084 20.2 0.4 5.3 4 1 1 5 5 5 2 Altered inheritance of mitochondria protein 3 ELO PF01151.18 EPS25144.1 - 1.4e-85 286.8 4.6 1.7e-85 286.6 4.6 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Rib_recp_KP_reg PF05104.12 EPS25144.1 - 9 7.3 14.1 0.87 10.6 9.7 1.5 2 0 0 2 2 2 0 Ribosome receptor lysine/proline rich region Glyco_hydro_35 PF01301.19 EPS25145.1 - 1.7e-85 287.4 1.3 3.4e-85 286.4 1.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 EPS25145.1 - 1.8e-58 197.4 0.1 3.5e-58 196.4 0.1 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 EPS25145.1 - 2e-58 195.9 11.4 5e-35 120.5 0.4 3.4 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 EPS25145.1 - 1.1e-27 95.4 0.2 2.3e-27 94.3 0.2 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Cellulase PF00150.18 EPS25145.1 - 7.1e-05 22.4 0.4 0.00014 21.4 0.4 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Amidohydro_2 PF04909.14 EPS25145.1 - 0.036 13.9 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase ELL PF10390.9 EPS25148.1 - 0.0059 16.1 0.0 0.0059 16.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase II elongation factor ELL AMP-binding PF00501.28 EPS25150.1 - 6.6e-39 133.7 0.0 9.4e-39 133.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EPS25150.1 - 2.5e-06 28.3 0.0 4.7e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Sulfotransfer_1 PF00685.27 EPS25151.1 - 3.1e-50 171.1 0.1 1.5e-49 168.8 0.1 1.8 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EPS25151.1 - 9.7e-13 49.0 0.0 7.5e-10 39.6 0.1 2.2 2 0 0 2 2 2 2 Sulfotransferase family DUF977 PF06163.11 EPS25151.1 - 0.064 13.2 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) Sulphotransf PF09037.10 EPS25151.1 - 0.072 12.6 0.1 1.8 8.0 0.0 2.4 2 0 0 2 2 2 0 Stf0 sulphotransferase Hexapep PF00132.24 EPS25152.1 - 2.7e-07 30.1 8.6 0.00092 18.9 0.7 3.5 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EPS25152.1 - 0.00039 20.8 0.0 0.00074 19.9 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.23 EPS25152.1 - 0.00065 19.4 0.0 0.001 18.7 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Fucokinase PF07959.12 EPS25152.1 - 0.0016 17.5 0.2 0.0026 16.8 0.2 1.2 1 0 0 1 1 1 1 L-fucokinase DUF4954 PF16314.5 EPS25152.1 - 0.014 13.6 1.0 0.021 13.0 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Spt20 PF12090.8 EPS25154.1 - 2.1e-55 187.9 9.6 2.1e-55 187.9 9.6 7.4 4 2 2 6 6 6 2 Spt20 family Guanylate_kin PF00625.21 EPS25155.1 - 0.013 15.2 0.6 0.017 14.8 0.4 1.4 1 1 0 1 1 1 0 Guanylate kinase zf-C2H2 PF00096.26 EPS25156.1 - 1.5e-08 34.6 12.5 0.00033 20.9 3.6 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EPS25156.1 - 0.00014 22.1 4.8 0.00014 22.1 4.8 3.6 3 1 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EPS25156.1 - 0.0002 21.9 8.9 0.0063 17.2 3.0 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 EPS25156.1 - 0.0017 19.0 4.9 0.48 11.1 0.5 2.5 1 1 1 2 2 2 2 FOXP coiled-coil domain Sina PF03145.16 EPS25156.1 - 0.11 12.5 2.1 0.17 11.8 2.1 1.2 1 0 0 1 1 1 0 Seven in absentia protein family zf-C2H2_6 PF13912.6 EPS25156.1 - 6.1 7.0 15.4 2.9 8.0 0.6 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger DegQ PF08181.11 EPS25157.1 - 0.092 12.9 0.2 0.13 12.4 0.2 1.3 1 0 0 1 1 1 0 DegQ (SacQ) family MFS_1 PF07690.16 EPS25160.1 - 6e-17 61.6 34.2 1.2e-09 37.6 1.7 2.8 1 1 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EPS25160.1 - 6.3e-07 28.1 0.2 6.3e-07 28.1 0.2 1.5 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Ribonuclease_T2 PF00445.18 EPS25161.1 - 2.8e-42 145.0 0.2 4.6e-42 144.3 0.2 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family BCNT PF07572.12 EPS25162.1 - 2.9e-26 91.3 0.4 8e-26 89.9 0.4 1.7 1 0 0 1 1 1 1 Bucentaur or craniofacial development CDC45 PF02724.14 EPS25162.1 - 2.5 6.3 10.6 3.4 5.8 10.6 1.2 1 0 0 1 1 1 0 CDC45-like protein LIFR_N PF18207.1 EPS25163.1 - 0.11 12.8 0.1 0.22 12.0 0.1 1.4 1 0 0 1 1 1 0 Leukemia inhibitory factor receptor N-terminal domain TrkH PF02386.16 EPS25165.1 - 6.7e-58 196.4 11.6 9.2e-56 189.3 5.0 2.2 2 0 0 2 2 2 2 Cation transport protein F-box PF00646.33 EPS25166.1 - 0.002 18.0 0.3 0.0061 16.4 0.3 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EPS25166.1 - 0.094 12.6 0.0 0.23 11.4 0.0 1.7 1 0 0 1 1 1 0 F-box-like F-box_4 PF15966.5 EPS25166.1 - 0.13 12.2 0.8 0.22 11.4 0.2 1.8 2 0 0 2 2 2 0 F-box Amidohydro_2 PF04909.14 EPS25167.1 - 4.8e-06 26.6 0.0 7.4e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.20 EPS25167.1 - 0.0006 19.2 0.0 0.0012 18.2 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase family LysR_substrate PF03466.20 EPS25167.1 - 0.031 13.7 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 LysR substrate binding domain Mis12 PF05859.12 EPS25168.1 - 4.7e-46 156.2 0.0 7.4e-46 155.6 0.0 1.3 1 0 0 1 1 1 1 Mis12 protein CENP-X PF09415.10 EPS25170.1 - 9.1e-29 99.6 0.1 1.8e-28 98.6 0.1 1.5 1 0 0 1 1 1 1 CENP-S associating Centromere protein X CBFD_NFYB_HMF PF00808.23 EPS25170.1 - 0.0021 18.3 0.1 0.0057 16.9 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Macro PF01661.21 EPS25171.1 - 9.3e-06 25.7 0.0 1.2e-05 25.4 0.0 1.1 1 0 0 1 1 1 1 Macro domain MJ1316 PF04457.12 EPS25172.1 - 5.6e-18 65.4 1.1 1.1e-17 64.5 1.1 1.5 1 0 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain MIF PF01187.18 EPS25172.1 - 4e-10 40.0 0.0 7.2e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Dus PF01207.17 EPS25173.1 - 6.2e-59 199.6 0.0 1e-58 198.9 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DHO_dh PF01180.21 EPS25173.1 - 0.0057 15.9 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase GETHR PF05671.11 EPS25173.1 - 0.086 12.2 18.2 0.25 10.8 18.2 1.8 1 0 0 1 1 1 0 GETHR pentapeptide repeat (5 copies) ANAPC4_WD40 PF12894.7 EPS25174.1 - 0.00017 21.8 1.6 0.91 9.9 0.1 4.4 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EPS25174.1 - 0.041 14.8 7.5 3 8.9 0.5 4.8 4 1 0 4 4 4 0 WD domain, G-beta repeat PD40 PF07676.12 EPS25174.1 - 0.1 12.6 0.3 0.59 10.1 0.1 2.4 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Ribosomal_S25 PF03297.15 EPS25175.1 - 4.8e-38 129.4 5.1 5.2e-38 129.3 5.1 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_11 PF08279.12 EPS25175.1 - 0.021 14.7 0.2 0.03 14.3 0.2 1.4 1 0 0 1 1 1 0 HTH domain HTH_DeoR PF08220.12 EPS25175.1 - 0.022 14.5 0.3 0.03 14.0 0.3 1.2 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain MarR_2 PF12802.7 EPS25175.1 - 0.061 13.2 0.1 0.074 12.9 0.1 1.2 1 0 0 1 1 1 0 MarR family HTH_24 PF13412.6 EPS25175.1 - 0.09 12.3 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Cyt-b5 PF00173.28 EPS25176.1 - 5.6e-10 39.2 0.0 7.4e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Gtr1_RagA PF04670.12 EPS25177.1 - 1.4e-68 230.7 0.0 2.1e-68 230.2 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 EPS25177.1 - 8.1e-05 22.1 0.0 0.00016 21.2 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EPS25177.1 - 0.0085 16.2 0.0 0.032 14.3 0.0 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 EPS25177.1 - 0.014 15.6 0.0 0.029 14.6 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 EPS25177.1 - 0.029 13.9 0.0 0.043 13.3 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EPS25177.1 - 0.029 13.8 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EPS25177.1 - 0.032 14.6 0.0 0.063 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 EPS25177.1 - 0.12 12.4 0.0 0.31 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EPS25178.1 - 3.5e-48 163.5 5.9 1.6e-45 154.8 5.9 2.2 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EPS25178.1 - 1.7e-20 72.7 0.1 1.7e-15 56.7 0.0 3.0 3 0 0 3 3 3 2 Cobalamin synthesis protein cobW C-terminal domain TsaE PF02367.17 EPS25178.1 - 0.0022 18.0 0.0 0.0052 16.8 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE MobB PF03205.14 EPS25178.1 - 0.0045 16.9 0.2 0.0092 15.9 0.2 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Spt5_N PF11942.8 EPS25178.1 - 0.0084 17.1 10.3 0.027 15.5 10.3 1.9 1 0 0 1 1 1 1 Spt5 transcription elongation factor, acidic N-terminal DUF4637 PF15470.6 EPS25178.1 - 0.013 15.2 0.7 0.032 14.0 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) AAA_16 PF13191.6 EPS25178.1 - 0.019 15.3 0.7 0.044 14.2 0.1 2.1 2 1 0 2 2 2 0 AAA ATPase domain Viral_helicase1 PF01443.18 EPS25178.1 - 0.02 14.6 0.2 0.071 12.8 0.1 1.9 1 1 1 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA PF00004.29 EPS25178.1 - 0.02 15.3 1.5 0.73 10.3 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EPS25178.1 - 0.028 14.6 0.1 0.17 12.1 0.2 2.2 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EPS25178.1 - 0.042 13.1 0.0 0.084 12.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin T2SSE PF00437.20 EPS25178.1 - 0.045 12.8 0.6 0.11 11.5 0.1 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein ATPase_2 PF01637.18 EPS25178.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 EPS25178.1 - 0.1 12.4 0.1 0.27 11.0 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EPS25178.1 - 0.12 12.8 0.0 0.3 11.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 EPS25178.1 - 0.14 12.4 1.0 0.87 9.9 1.0 2.4 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 EPS25178.1 - 0.17 10.8 0.5 3.1 6.7 0.0 2.5 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB adh_short PF00106.25 EPS25179.1 - 1.3e-31 109.6 0.2 2.1e-31 108.9 0.1 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS25179.1 - 3.8e-19 69.2 0.0 5.7e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPS25179.1 - 0.0081 16.1 0.1 0.024 14.6 0.1 1.8 1 1 0 1 1 1 1 KR domain His_Phos_2 PF00328.22 EPS25180.1 - 7.7e-10 38.7 0.1 1.4e-07 31.3 0.2 3.0 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Lactamase_B_4 PF13691.6 EPS25181.1 - 1.8e-24 85.2 0.2 7.8e-24 83.1 0.0 2.2 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 EPS25181.1 - 1.3e-11 44.4 0.0 2.7e-05 23.8 0.0 2.5 2 0 0 2 2 2 2 Beta-lactamase superfamily domain SurA_N_2 PF13623.6 EPS25181.1 - 3.5 7.5 6.4 0.66 9.8 2.1 2.0 2 0 0 2 2 2 0 SurA N-terminal domain bZIP_1 PF00170.21 EPS25182.1 - 2.2e-07 30.8 11.3 5.1e-07 29.7 11.3 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EPS25182.1 - 0.0012 18.9 12.0 0.0046 17.0 12.0 2.1 1 0 0 1 1 1 1 Basic region leucine zipper LOR PF04525.12 EPS25183.1 - 2.1e-08 34.0 0.0 2.8e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 LURP-one-related DUF2897 PF11446.8 EPS25183.1 - 0.17 11.8 0.3 0.38 10.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) Thaumatin PF00314.17 EPS25184.1 - 0.059 13.0 0.3 0.072 12.7 0.3 1.1 1 0 0 1 1 1 0 Thaumatin family Peptidase_S24 PF00717.23 EPS25185.1 - 4.8e-07 29.6 0.0 7.4e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like MBOAT_2 PF13813.6 EPS25186.1 - 2.2e-22 79.1 1.2 5.4e-22 77.9 1.2 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family ABC_membrane_2 PF06472.15 EPS25188.1 - 1.7e-104 349.0 0.9 2e-104 348.7 0.2 1.5 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EPS25188.1 - 1e-18 68.2 0.0 2e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EPS25188.1 - 5.8e-05 23.1 0.0 0.00018 21.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EPS25188.1 - 0.0049 17.4 0.0 0.012 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EPS25188.1 - 0.019 14.7 0.0 0.053 13.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.19 EPS25188.1 - 0.026 13.9 0.0 0.13 11.7 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain RuvB_N PF05496.12 EPS25188.1 - 0.066 12.9 0.0 1.7 8.4 0.0 2.5 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_27 PF13514.6 EPS25188.1 - 0.11 12.1 0.0 0.3 10.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EPS25188.1 - 0.13 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_15 PF13175.6 EPS25188.1 - 0.17 11.6 0.1 0.43 10.2 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain HAD PF12710.7 EPS25189.1 - 2e-26 93.6 0.0 3e-26 93.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EPS25189.1 - 0.0013 18.2 0.0 0.44 9.9 0.0 2.1 2 0 0 2 2 2 2 Putative Phosphatase Hydrolase PF00702.26 EPS25189.1 - 0.0054 17.1 0.1 0.025 14.8 0.1 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Phosphorylase PF00343.20 EPS25190.1 - 0 1059.3 0.0 0 1059.1 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase G-alpha PF00503.20 EPS25193.1 - 1.1e-113 380.0 0.4 1.3e-113 379.8 0.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EPS25193.1 - 3.6e-15 55.8 1.5 2.3e-10 40.2 0.2 2.7 2 2 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EPS25193.1 - 9.3e-05 21.9 0.1 0.16 11.3 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 EPS25193.1 - 0.0033 17.6 0.3 1 9.6 0.1 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EPS25193.1 - 0.078 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pkinase PF00069.25 EPS25194.1 - 5.3e-68 229.2 0.0 6.8e-68 228.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS25194.1 - 1.9e-31 109.3 0.0 2.3e-31 109.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EPS25194.1 - 1.2e-05 24.5 0.1 1.5e-05 24.1 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EPS25194.1 - 0.00018 21.0 0.1 0.0006 19.2 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EPS25194.1 - 0.00029 20.2 0.0 0.057 12.7 0.0 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.23 EPS25194.1 - 0.001 19.1 0.0 0.0024 17.9 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 EPS25194.1 - 0.014 15.1 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EPS25194.1 - 0.047 13.3 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Avl9 PF09794.9 EPS25195.1 - 2.4e-136 454.4 0.0 3.3e-136 453.9 0.0 1.2 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 EPS25195.1 - 3e-07 30.4 0.0 0.00083 19.3 0.0 2.5 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.9 EPS25195.1 - 0.076 12.6 3.0 0.94 9.0 0.7 3.5 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2347) Cullin PF00888.22 EPS25196.1 - 2.3e-194 647.5 14.7 3.1e-194 647.1 14.7 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EPS25196.1 - 1.1e-26 92.6 2.3 1.1e-26 92.6 2.3 2.5 3 0 0 3 3 3 1 Cullin protein neddylation domain WAC_Acf1_DNA_bd PF10537.9 EPS25196.1 - 0.097 13.2 2.8 0.26 11.8 0.6 2.9 2 0 0 2 2 2 0 ATP-utilising chromatin assembly and remodelling N-terminal Cupin_2 PF07883.11 EPS25197.1 - 3.3e-07 29.9 0.4 1.8e-06 27.6 0.2 2.0 1 1 1 2 2 2 1 Cupin domain Cupin_1 PF00190.22 EPS25197.1 - 4.8e-06 26.3 0.2 7.4e-06 25.6 0.2 1.2 1 0 0 1 1 1 1 Cupin ARD PF03079.14 EPS25197.1 - 0.0013 19.0 0.0 0.0017 18.6 0.0 1.3 1 0 0 1 1 1 1 ARD/ARD' family Cupin_6 PF12852.7 EPS25197.1 - 0.0026 17.5 0.1 0.0031 17.2 0.1 1.1 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.19 EPS25197.1 - 0.12 12.3 0.3 0.16 11.8 0.3 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain MARVEL PF01284.23 EPS25198.1 - 0.2 11.7 3.4 0.35 10.9 3.4 1.4 1 1 0 1 1 1 0 Membrane-associating domain Mit_KHE1 PF10173.9 EPS25199.1 - 1.3e-63 214.6 1.0 1.3e-63 214.6 1.0 1.7 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related End3 PF12761.7 EPS25200.1 - 1.4e-69 234.2 1.8 2e-69 233.8 1.8 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.7 EPS25200.1 - 5e-50 167.8 0.1 1.8e-47 159.6 0.1 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 EPS25200.1 - 1e-07 31.0 0.3 2.6e-07 29.7 0.3 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EPS25200.1 - 8.1e-07 29.4 0.1 3.1e-06 27.5 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EPS25200.1 - 3.4e-05 23.6 0.0 0.0042 16.9 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EPS25200.1 - 0.0002 21.0 0.1 0.00064 19.5 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 EPS25200.1 - 0.0024 17.3 0.2 0.0081 15.6 0.2 1.9 1 0 0 1 1 1 1 EF hand Spc7 PF08317.11 EPS25200.1 - 0.34 9.7 12.1 0.032 13.1 5.9 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein Med9 PF07544.13 EPS25200.1 - 0.51 10.5 4.4 3.9 7.6 0.2 2.7 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 TPR_MLP1_2 PF07926.12 EPS25200.1 - 1.6 8.8 13.0 0.48 10.5 5.0 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF4201 PF13870.6 EPS25200.1 - 2.2 8.0 12.0 0.32 10.7 5.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF4407 PF14362.6 EPS25200.1 - 2.8 7.2 6.4 4.3 6.6 6.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Rx_N PF18052.1 EPS25200.1 - 4.6 7.6 7.4 1.4 9.2 0.8 2.5 1 1 0 2 2 2 0 Rx N-terminal domain SNF2_N PF00176.23 EPS25201.1 - 4.1e-64 216.5 0.1 1.9e-63 214.3 0.1 1.8 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EPS25201.1 - 2.5e-21 76.1 0.0 1.4e-20 73.7 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPS25201.1 - 4.1e-07 30.1 0.3 2.8e-06 27.4 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EPS25201.1 - 9.1e-07 28.3 2.3 9.4e-07 28.3 0.0 2.0 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase DEAD PF00270.29 EPS25201.1 - 0.0027 17.5 0.0 0.0082 15.9 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.8 EPS25201.1 - 0.0034 16.6 3.6 0.013 14.7 0.0 3.0 3 1 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 YjbT PF17089.5 EPS25201.1 - 0.18 11.8 0.0 0.53 10.3 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised protein family DSPc PF00782.20 EPS25203.1 - 7.5e-14 51.7 0.0 1.2e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EPS25203.1 - 0.0022 18.3 0.0 0.0033 17.7 0.0 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 EPS25203.1 - 0.14 11.7 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF442 PF04273.13 EPS25203.1 - 0.15 12.1 0.0 1.5 8.9 0.0 2.2 1 1 0 1 1 1 0 Putative phosphatase (DUF442) zf-C2H2_aberr PF17017.5 EPS25204.1 - 6.8e-07 29.6 0.3 1.3e-06 28.7 0.0 1.6 2 0 0 2 2 2 1 Aberrant zinc-finger zf-C2H2 PF00096.26 EPS25204.1 - 2.3e-06 27.7 14.3 0.19 12.3 2.5 3.8 3 1 0 3 3 3 3 Zinc finger, C2H2 type Trimer_CC PF08954.11 EPS25204.1 - 0.00073 19.0 1.0 0.0021 17.5 0.3 2.1 2 0 0 2 2 2 1 Trimerisation motif Transpos_assoc PF13963.6 EPS25204.1 - 0.0089 16.3 1.2 0.18 12.1 0.1 2.3 2 0 0 2 2 2 1 Transposase-associated domain zf-C2H2_4 PF13894.6 EPS25204.1 - 0.018 15.9 6.7 13 6.9 0.4 3.7 3 1 0 3 3 3 0 C2H2-type zinc finger CCDC92 PF14916.6 EPS25204.1 - 0.042 13.6 0.4 0.11 12.3 0.2 1.8 1 1 0 1 1 1 0 Coiled-coil domain of unknown function Cnn_1N PF07989.11 EPS25204.1 - 0.045 13.9 0.4 0.14 12.3 0.3 1.9 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 T3SS_needle_E PF08988.10 EPS25204.1 - 0.087 13.0 1.6 0.21 11.8 1.6 1.6 1 0 0 1 1 1 0 Type III secretion system, cytoplasmic E component of needle MPS2 PF17060.5 EPS25204.1 - 0.12 11.6 1.1 2.6 7.2 0.7 2.1 1 1 0 2 2 2 0 Monopolar spindle protein 2 OrsD PF12013.8 EPS25204.1 - 0.12 12.8 0.0 0.12 12.8 0.0 2.8 2 2 1 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-H2C2_2 PF13465.6 EPS25204.1 - 0.14 12.7 0.2 0.14 12.7 0.2 3.4 3 0 0 3 3 3 0 Zinc-finger double domain UPF1_Zn_bind PF09416.10 EPS25205.1 - 3.9e-72 241.2 3.3 4.3e-72 241.1 1.7 1.9 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 EPS25205.1 - 3e-59 200.0 0.0 6.3e-59 198.9 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EPS25205.1 - 9.5e-54 182.9 3.0 1e-30 107.5 0.3 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 EPS25205.1 - 1.2e-33 115.2 0.0 2.4e-33 114.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 EPS25205.1 - 2.2e-13 50.4 0.4 5e-12 45.9 0.4 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EPS25205.1 - 5.3e-11 43.1 0.1 3.2e-10 40.5 0.1 2.3 2 1 0 2 2 2 1 AAA domain ResIII PF04851.15 EPS25205.1 - 1e-05 25.6 0.0 1.9e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 EPS25205.1 - 1.2e-05 25.1 0.2 0.12 12.1 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 EPS25205.1 - 0.00052 19.9 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 Helicase DUF2075 PF09848.9 EPS25205.1 - 0.0007 18.9 0.1 0.013 14.7 0.0 2.5 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.21 EPS25205.1 - 0.0017 18.0 0.0 0.039 13.5 0.0 2.6 2 1 0 3 3 3 1 UvrD/REP helicase N-terminal domain PIF1 PF05970.14 EPS25205.1 - 0.0031 16.7 0.1 0.57 9.3 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase DEAD PF00270.29 EPS25205.1 - 0.014 15.2 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_10 PF12846.7 EPS25205.1 - 0.034 13.1 0.0 0.053 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain ATPase PF06745.13 EPS25205.1 - 0.05 12.9 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.6 EPS25205.1 - 0.12 12.6 0.1 0.33 11.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EPS25205.1 - 0.24 11.8 0.4 0.65 10.4 0.4 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Brix PF04427.18 EPS25206.1 - 1.5e-31 110.0 0.0 1.9e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 Brix domain PTCB-BRCT PF12738.7 EPS25207.1 - 3.6e-05 23.6 0.1 0.0001 22.2 0.1 1.8 1 1 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 EPS25207.1 - 0.00012 22.4 0.0 0.00022 21.5 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain WGR PF05406.15 EPS25207.1 - 0.00026 21.0 0.0 0.00068 19.6 0.0 1.7 1 0 0 1 1 1 1 WGR domain BRCT_2 PF16589.5 EPS25207.1 - 0.036 14.5 0.0 0.073 13.5 0.0 1.5 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain IGPS PF00218.21 EPS25208.1 - 6.8e-97 323.6 0.1 1.7e-96 322.3 0.0 1.7 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.22 EPS25208.1 - 5.6e-58 195.9 0.1 5.3e-54 182.9 0.0 2.6 2 1 1 3 3 3 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.28 EPS25208.1 - 1.1e-46 159.0 0.0 2.3e-46 158.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EPS25208.1 - 8.8e-05 22.3 0.8 0.00042 20.2 0.8 2.0 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.19 EPS25208.1 - 0.00048 19.9 0.6 0.044 13.6 0.0 3.4 3 0 0 3 3 3 1 Quinolinate phosphoribosyl transferase, C-terminal domain IMPDH PF00478.25 EPS25208.1 - 0.0026 16.8 0.2 2.7 6.9 0.1 3.2 2 1 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 EPS25208.1 - 0.016 14.6 0.7 0.16 11.4 0.0 2.5 3 0 0 3 3 3 0 Histidine biosynthesis protein NanE PF04131.14 EPS25208.1 - 0.12 11.5 2.9 0.6 9.3 0.0 2.9 4 0 0 4 4 4 0 Putative N-acetylmannosamine-6-phosphate epimerase Nup188_C PF18378.1 EPS25209.1 - 6.4e-144 479.3 0.1 1.2e-143 478.4 0.1 1.5 1 0 0 1 1 1 1 Nuclear pore protein NUP188 C-terminal domain Nup188 PF10487.9 EPS25209.1 - 1.1e-78 265.2 0.0 5.8e-78 262.8 0.0 2.0 1 1 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 Mso1_C PF14477.6 EPS25209.1 - 8.8 6.8 7.2 1.8 9.1 0.6 2.8 3 0 0 3 3 3 0 Membrane-polarising domain of Mso1 AMP-binding PF00501.28 EPS25210.1 - 1.8e-89 300.3 0.0 2.3e-89 299.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EPS25210.1 - 1.5e-14 54.7 0.2 3.7e-14 53.4 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Use1 PF09753.9 EPS25213.1 - 3e-07 30.4 6.8 3e-07 30.4 6.8 2.0 1 1 0 2 2 2 1 Membrane fusion protein Use1 Tmemb_cc2 PF10267.9 EPS25213.1 - 0.27 10.3 14.4 0.37 9.9 14.4 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein PRCC PF10253.9 EPS25213.1 - 0.8 10.4 16.5 1.4 9.7 16.5 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF572 PF04502.13 EPS25213.1 - 1.1 8.8 16.1 1.5 8.3 16.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Synaptobrevin PF00957.21 EPS25213.1 - 8.8 6.2 6.0 2.6 7.9 1.0 2.5 2 1 1 3 3 3 0 Synaptobrevin G-alpha PF00503.20 EPS25214.1 - 5.1e-124 414.0 1.7 5.8e-124 413.8 1.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EPS25214.1 - 2.6e-15 56.3 1.7 2.4e-10 40.1 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.20 EPS25214.1 - 7.5e-05 22.5 0.0 0.00033 20.4 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Gtr1_RagA PF04670.12 EPS25214.1 - 0.0028 17.0 3.2 0.082 12.2 0.1 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 EPS25214.1 - 0.017 15.4 0.7 2.4 8.4 0.0 2.9 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EPS25214.1 - 0.018 14.8 0.0 0.046 13.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EPS25214.1 - 0.075 13.5 0.2 0.17 12.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 EPS25214.1 - 0.079 12.5 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MCM PF00493.23 EPS25214.1 - 0.079 12.0 0.1 0.17 11.0 0.1 1.5 1 1 0 1 1 1 0 MCM P-loop domain FtsK_SpoIIIE PF01580.18 EPS25214.1 - 0.13 11.6 0.0 0.32 10.3 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 EPS25214.1 - 0.14 12.3 0.1 8.9 6.4 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase HNH_2 PF13391.6 EPS25215.1 - 0.0062 16.6 0.2 0.008 16.3 0.2 1.4 1 1 0 1 1 1 1 HNH endonuclease DUF1771 PF08590.10 EPS25216.1 - 3.8e-26 91.2 7.7 1.2e-25 89.7 7.7 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 EPS25216.1 - 1.7e-10 41.1 1.5 4.1e-10 39.9 0.2 2.3 2 0 0 2 2 2 1 Smr domain Spore_YhcN_YlaJ PF09580.10 EPS25216.1 - 0.0092 16.1 0.5 0.0092 16.1 0.5 2.0 2 1 0 2 2 2 1 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Mlh1_C PF16413.5 EPS25216.1 - 0.029 13.8 0.1 0.057 12.8 0.1 1.4 1 0 0 1 1 1 0 DNA mismatch repair protein Mlh1 C-terminus baeRF_family12 PF18856.1 EPS25216.1 - 0.17 12.5 0.3 0.17 12.5 0.3 2.5 2 1 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 12 DUF4407 PF14362.6 EPS25216.1 - 0.59 9.4 7.7 0.47 9.8 3.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) OmpH PF03938.14 EPS25216.1 - 3.6 7.9 15.4 3.7 7.9 3.1 2.4 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) polyprenyl_synt PF00348.17 EPS25217.1 - 5.8e-66 222.2 0.0 7.1e-66 221.9 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DUF5435 PF17503.2 EPS25217.1 - 0.077 12.7 0.1 0.66 9.7 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5435) KN17_SH3 PF18131.1 EPS25217.1 - 0.13 12.4 0.0 5.3 7.2 0.0 2.7 2 1 0 2 2 2 0 KN17 SH3-like C-terminal domain DUF489 PF04356.12 EPS25217.1 - 0.14 12.1 0.1 0.35 10.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF489) CDC14 PF08045.11 EPS25218.1 - 5.9e-129 429.2 0.0 6.6e-129 429.0 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component Methyltransf_25 PF13649.6 EPS25219.1 - 1.2e-09 38.7 0.1 7.6e-08 33.0 0.1 3.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPS25219.1 - 3.5e-09 36.6 0.0 7.8e-09 35.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPS25219.1 - 1.2e-08 35.0 0.0 1.8e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS25219.1 - 1.5e-08 35.1 0.1 4.4e-07 30.5 0.1 2.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPS25219.1 - 2.9e-06 27.9 0.0 8.9e-06 26.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPS25219.1 - 7.6e-05 22.1 0.0 0.00011 21.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EPS25219.1 - 0.0091 15.3 0.0 0.34 10.1 0.0 2.3 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 EPS25219.1 - 0.016 15.0 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_7 PF03492.15 EPS25219.1 - 0.025 13.8 0.0 0.051 12.8 0.0 1.5 2 0 0 2 2 2 0 SAM dependent carboxyl methyltransferase TehB PF03848.14 EPS25219.1 - 0.16 11.4 0.1 0.68 9.3 0.0 2.0 1 1 0 2 2 2 0 Tellurite resistance protein TehB GST_N_4 PF17172.4 EPS25220.1 - 5.9e-23 81.5 0.1 1.1e-22 80.6 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 EPS25220.1 - 5.5e-19 67.7 0.1 1.1e-18 66.7 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 EPS25220.1 - 6.6e-13 49.1 0.2 1.1e-12 48.3 0.2 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein SAM35 PF10806.8 EPS25220.1 - 1.2e-05 25.6 0.4 2.3e-05 24.7 0.1 1.6 2 0 0 2 2 2 1 SAM35, subunit of SAM coomplex GST_C_2 PF13410.6 EPS25220.1 - 0.014 15.4 0.1 0.033 14.2 0.1 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Copper-fist PF00649.18 EPS25221.1 - 4e-18 64.6 0.4 1.1e-17 63.3 0.4 1.8 1 0 0 1 1 1 1 Copper fist DNA binding domain Metallothio_2 PF01439.18 EPS25221.1 - 0.093 13.6 0.9 0.093 13.6 0.9 4.4 5 2 0 5 5 5 0 Metallothionein Urb2 PF10441.9 EPS25222.1 - 3.6e-60 203.4 1.5 7.5e-60 202.4 0.1 2.4 2 0 0 2 2 2 1 Urb2/Npa2 family DUF543 PF04418.12 EPS25223.1 - 7.4e-29 99.6 0.1 8.7e-29 99.3 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Transp_cyt_pur PF02133.15 EPS25224.1 - 1.1e-152 508.9 38.3 1.3e-152 508.7 38.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PI-PLC-X PF00388.19 EPS25225.1 - 1.9e-59 199.4 0.0 3.6e-59 198.5 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EPS25225.1 - 5.4e-44 149.2 1.0 3.8e-42 143.3 0.5 2.6 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.11 EPS25225.1 - 2.2e-05 24.9 0.6 0.00052 20.4 0.2 2.4 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_1 PF00036.32 EPS25225.1 - 0.00022 20.5 0.0 0.00065 19.1 0.0 1.9 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EPS25225.1 - 0.00037 20.9 0.3 0.35 11.3 0.0 3.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EPS25225.1 - 0.0026 17.6 0.2 0.23 11.5 0.1 3.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 EPS25225.1 - 0.0061 16.4 0.1 0.031 14.1 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair GDPD PF03009.17 EPS25225.1 - 0.0064 16.3 0.0 0.017 14.9 0.0 1.6 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family SMC_ScpA PF02616.14 EPS25225.1 - 0.22 11.4 1.1 0.81 9.5 0.2 2.0 2 0 0 2 2 2 0 Segregation and condensation protein ScpA RVT_1 PF00078.27 EPS25227.1 - 0.014 14.9 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) Coatomer_E PF04733.14 EPS25229.1 - 1.5e-58 198.5 7.0 1.8e-58 198.3 7.0 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 EPS25229.1 - 5.9e-10 39.5 26.7 0.0022 18.5 1.2 4.4 3 2 1 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 EPS25229.1 - 1e-05 25.9 18.8 0.0095 16.7 0.3 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 EPS25229.1 - 4.4e-05 24.0 22.2 0.0024 18.5 3.8 4.1 1 1 5 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EPS25229.1 - 5.7e-05 23.3 6.1 2.1 8.6 0.1 3.6 2 1 2 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EPS25229.1 - 0.00038 20.9 7.0 0.033 14.8 0.2 3.7 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 EPS25229.1 - 0.0031 18.0 24.0 0.24 12.1 0.1 5.9 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 EPS25229.1 - 0.0088 16.3 18.2 0.12 12.7 0.5 4.8 3 1 1 4 4 4 1 Tetratricopeptide repeat DHR-2 PF06920.13 EPS25229.1 - 0.009 14.7 0.2 0.011 14.4 0.2 1.1 1 0 0 1 1 1 1 Dock homology region 2 TPR_2 PF07719.17 EPS25229.1 - 0.025 14.7 0.1 0.025 14.7 0.1 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat PLU-1 PF08429.11 EPS25229.1 - 0.038 13.1 0.1 0.058 12.6 0.1 1.3 1 0 0 1 1 1 0 PLU-1-like protein TPR_1 PF00515.28 EPS25229.1 - 0.12 12.2 3.3 0.39 10.6 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 EPS25229.1 - 0.16 11.9 7.1 0.89 9.4 0.5 2.9 1 1 2 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal TPR_9 PF13371.6 EPS25229.1 - 0.17 12.0 0.2 0.17 12.0 0.2 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 EPS25229.1 - 1.4 9.3 10.5 1 9.8 4.1 3.4 2 1 0 3 3 3 0 Tetratricopeptide repeat Abhydrolase_3 PF07859.13 EPS25230.1 - 3e-27 95.8 0.0 4.3e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EPS25230.1 - 1.7e-20 73.3 0.0 2.4e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_2 PF02230.16 EPS25230.1 - 0.0024 17.7 0.0 0.066 13.0 0.0 2.6 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase DUF2974 PF11187.8 EPS25230.1 - 0.0034 17.0 0.0 0.0067 16.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) PGAP1 PF07819.13 EPS25230.1 - 0.12 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein PMI_typeI PF01238.21 EPS25231.1 - 1.6e-145 485.1 0.0 1.8e-145 484.8 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.19 EPS25231.1 - 0.033 14.1 0.5 7.6 6.4 0.1 3.1 4 0 0 4 4 4 0 AraC-like ligand binding domain DUF3972 PF13118.6 EPS25231.1 - 0.06 13.8 0.5 0.14 12.6 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) Cupin_2 PF07883.11 EPS25231.1 - 0.091 12.5 0.2 1.6 8.5 0.2 2.2 2 0 0 2 2 2 0 Cupin domain Muted PF14942.6 EPS25231.1 - 0.13 12.6 0.5 0.24 11.8 0.5 1.3 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein DUF1325 PF07039.11 EPS25232.1 - 8.2e-33 113.3 0.0 1.4e-32 112.5 0.0 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain LBR_tudor PF09465.10 EPS25232.1 - 0.016 15.0 0.0 0.031 14.1 0.0 1.4 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain Tudor_3 PF18115.1 EPS25232.1 - 0.059 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain GTP_cyclohydro2 PF00925.20 EPS25233.1 - 1.1e-58 197.4 0.0 1.5e-58 197.0 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II DUF3425 PF11905.8 EPS25234.1 - 4.9e-23 81.4 2.6 8.7e-23 80.6 2.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) DUF2730 PF10805.8 EPS25234.1 - 0.39 10.8 1.5 0.74 9.9 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Rox3 PF08633.10 EPS25234.1 - 0.45 10.8 3.5 0.15 12.3 0.6 1.6 2 0 0 2 2 2 0 Rox3 mediator complex subunit bZIP_1 PF00170.21 EPS25234.1 - 1.7 8.8 12.1 0.34 11.1 7.1 2.3 2 1 0 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.15 EPS25234.1 - 6.7 6.9 9.7 42 4.3 9.6 2.1 1 1 0 1 1 1 0 Basic region leucine zipper Hamartin PF04388.12 EPS25234.1 - 7.8 5.0 14.4 12 4.5 14.4 1.2 1 0 0 1 1 1 0 Hamartin protein NAD_binding_2 PF03446.15 EPS25235.1 - 4.5e-20 72.4 0.0 6.6e-20 71.9 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EPS25235.1 - 3.7e-11 43.3 0.0 7.2e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Zemlya PF17646.1 EPS25235.1 - 0.014 15.7 0.0 0.035 14.5 0.0 1.6 1 0 0 1 1 1 0 Closterovirus 1a polyprotein central region Shikimate_DH PF01488.20 EPS25235.1 - 0.067 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Actin PF00022.19 EPS25236.1 - 4.2e-112 374.7 0.0 2.9e-111 372.0 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EPS25236.1 - 0.025 13.4 0.0 0.082 11.7 0.0 1.9 1 1 0 1 1 1 0 MreB/Mbl protein adh_short_C2 PF13561.6 EPS25237.1 - 2.1e-58 197.7 0.0 2.6e-58 197.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPS25237.1 - 5.7e-46 156.5 0.0 7.3e-46 156.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPS25237.1 - 1.1e-12 48.3 0.0 1.6e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 EPS25237.1 - 0.021 14.2 0.0 1.4 8.2 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 EPS25237.1 - 0.065 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1776 PF08643.10 EPS25237.1 - 0.098 12.0 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) adh_short_C2 PF13561.6 EPS25238.1 - 1.8e-45 155.3 1.5 5.8e-45 153.7 1.5 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPS25238.1 - 3.9e-44 150.5 1.3 6e-44 149.8 1.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPS25238.1 - 4e-12 46.4 0.2 8.1e-12 45.4 0.1 1.6 1 1 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 EPS25238.1 - 0.0019 18.2 0.0 0.0043 17.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF1776 PF08643.10 EPS25238.1 - 0.0052 16.2 0.7 0.0082 15.5 0.2 1.5 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Shikimate_DH PF01488.20 EPS25238.1 - 0.017 15.2 0.4 0.034 14.2 0.4 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 EPS25238.1 - 0.049 13.0 0.2 0.13 11.6 0.1 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EPS25238.1 - 0.051 13.0 0.2 0.14 11.6 0.2 1.7 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Glyco_tran_WecB PF03808.13 EPS25238.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family DUF202 PF02656.15 EPS25239.1 - 4.9e-22 78.1 1.2 4.9e-22 78.1 1.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 EPS25239.1 - 0.061 13.2 8.2 0.11 12.4 8.2 1.4 1 0 0 1 1 1 0 SPX domain PTPA PF03095.15 EPS25240.1 - 2.7e-107 358.7 0.0 3.2e-107 358.5 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein MFS_1 PF07690.16 EPS25241.1 - 1.9e-14 53.4 11.4 1.9e-14 53.4 11.4 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS25241.1 - 1.5e-08 34.0 1.4 1.5e-08 34.0 1.4 2.6 2 2 0 2 2 2 1 Sugar (and other) transporter FAM176 PF14851.6 EPS25241.1 - 0.011 15.4 0.3 0.026 14.2 0.3 1.6 1 0 0 1 1 1 0 FAM176 family Neurensin PF14927.6 EPS25241.1 - 2.9 7.6 5.0 2.5 7.8 0.5 2.9 3 0 0 3 3 3 0 Neurensin HSP20 PF00011.21 EPS25242.1 - 5e-19 68.3 0.1 6.5e-16 58.3 0.1 2.2 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EPS25242.1 - 2.9e-05 23.5 0.0 0.00012 21.6 0.0 1.9 1 1 0 1 1 1 1 HSP20-like domain found in ArsA CpeS PF09367.10 EPS25242.1 - 0.036 14.0 0.6 0.056 13.4 0.6 1.2 1 0 0 1 1 1 0 CpeS-like protein DUF1754 PF08555.10 EPS25243.1 - 5.2e-18 65.6 13.2 5.2e-18 65.6 13.2 1.7 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) APS-reductase_C PF12139.8 EPS25243.1 - 0.1 12.8 0.6 0.18 12.0 0.6 1.4 1 0 0 1 1 1 0 Adenosine-5'-phosphosulfate reductase beta subunit Sec2p PF06428.11 EPS25243.1 - 0.47 10.4 6.6 0.061 13.3 1.8 1.9 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Trypan_PARP PF05887.11 EPS25243.1 - 1.5 8.8 8.8 2.1 8.3 8.8 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) zf-AN1 PF01428.16 EPS25244.1 - 1.4e-12 47.5 7.8 1.4e-12 47.5 7.8 1.6 1 1 0 1 1 1 1 AN1-like Zinc finger Transp_Tc5_C PF04236.15 EPS25244.1 - 0.047 14.1 6.0 0.047 14.1 6.0 1.5 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain Tubulin PF00091.25 EPS25247.1 - 7.3e-68 228.7 0.0 1.1e-67 228.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EPS25247.1 - 3.1e-45 153.4 0.5 5.8e-45 152.5 0.1 1.6 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EPS25247.1 - 1.3e-06 28.7 0.0 2.8e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 EPS25247.1 - 0.04 13.1 0.0 0.058 12.6 0.0 1.2 1 0 0 1 1 1 0 Tubulin like Tubulin_3 PF14881.6 EPS25247.1 - 0.15 11.8 0.1 0.38 10.4 0.0 1.7 2 0 0 2 2 2 0 Tubulin domain Aldo_ket_red PF00248.21 EPS25249.1 - 1.2e-54 185.5 0.0 1.4e-54 185.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family EamA PF00892.20 EPS25250.1 - 6.1e-12 45.9 26.0 5.9e-06 26.5 0.9 2.5 2 0 0 2 2 2 2 EamA-like transporter family CSG2 PF16965.5 EPS25250.1 - 5.2e-09 35.6 9.5 9.6e-09 34.7 8.9 1.9 1 1 0 1 1 1 1 Ceramide synthase regulator Phage_holin_2_4 PF16082.5 EPS25250.1 - 0.0029 17.3 0.1 1 9.1 0.0 2.7 2 0 0 2 2 2 2 Bacteriophage holin family, superfamily II-like Nuc_sug_transp PF04142.15 EPS25250.1 - 0.016 14.4 0.1 0.016 14.4 0.1 2.1 2 0 0 2 2 2 0 Nucleotide-sugar transporter DUF202 PF02656.15 EPS25250.1 - 0.052 14.0 16.8 0.092 13.2 3.7 4.8 3 1 0 3 3 3 0 Domain of unknown function (DUF202) DAP10 PF07213.11 EPS25250.1 - 1.3 9.0 4.1 68 3.5 0.5 3.5 4 0 0 4 4 4 0 DAP10 membrane protein Baculo_19 PF04798.12 EPS25252.1 - 0.16 11.7 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Baculovirus 19 kDa protein conserved region Methyltransf_34 PF11312.8 EPS25256.1 - 5.5e-104 347.7 0.3 9.4e-103 343.6 0.3 2.0 1 1 0 1 1 1 1 Putative SAM-dependent methyltransferase Noc2 PF03715.13 EPS25256.1 - 0.018 14.3 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 Noc2p family Rsm22 PF09243.10 EPS25256.1 - 0.086 12.1 0.1 0.25 10.6 0.1 1.8 1 1 1 2 2 2 0 Mitochondrial small ribosomal subunit Rsm22 DUF938 PF06080.12 EPS25256.1 - 0.14 11.9 0.2 3.7 7.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF938) TMP_2 PF06791.13 EPS25256.1 - 1.6 8.3 7.9 0.72 9.5 2.4 2.1 1 1 0 2 2 2 0 Prophage tail length tape measure protein Band_7 PF01145.25 EPS25257.1 - 2.3e-25 89.7 9.4 4e-25 88.8 8.8 1.7 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 EPS25257.1 - 0.00014 21.0 3.5 0.00019 20.6 3.5 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial UcrQ PF02939.16 EPS25258.1 - 1e-32 111.9 0.1 1.2e-32 111.7 0.1 1.1 1 0 0 1 1 1 1 UcrQ family Spermine_synth PF01564.17 EPS25259.1 - 4.9e-71 238.0 0.0 6.8e-71 237.6 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 EPS25259.1 - 7.4e-24 83.4 0.1 1.3e-23 82.6 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 EPS25259.1 - 0.0015 19.2 0.0 0.004 17.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPS25259.1 - 0.0071 17.1 0.1 0.13 13.0 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain 3HCDH_N PF02737.18 EPS25260.1 - 2.8e-25 89.3 0.0 5.4e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EPS25260.1 - 4.8e-10 39.9 0.0 9.6e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain RPN1_C PF18051.1 EPS25260.1 - 0.087 12.9 0.1 0.76 9.9 0.0 2.4 2 0 0 2 2 2 0 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal Transketolase_N PF00456.21 EPS25261.1 - 3e-151 503.1 0.1 3.9e-151 502.7 0.1 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EPS25261.1 - 2.1e-44 151.3 0.0 3.9e-44 150.4 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EPS25261.1 - 8.1e-13 48.3 0.0 1.8e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 EPS25261.1 - 0.0002 20.7 0.0 0.00031 20.1 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 EPS25261.1 - 0.0054 15.7 0.0 0.0098 14.9 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component Beta_elim_lyase PF01212.21 EPS25261.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase GFA PF04828.14 EPS25263.1 - 2e-25 88.9 0.4 2.5e-25 88.6 0.4 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.6 EPS25263.1 - 0.02 14.8 0.4 0.02 14.8 0.4 2.7 2 1 1 3 3 3 0 Nudix N-terminal Sugar_tr PF00083.24 EPS25264.1 - 1.1e-136 456.3 26.3 1.3e-136 456.1 26.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS25264.1 - 5e-25 88.2 47.3 1.9e-18 66.5 20.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3959 PF13105.6 EPS25264.1 - 1.2 8.6 4.5 2.5 7.5 4.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) PRA1 PF03208.19 EPS25264.1 - 2 8.0 7.0 0.34 10.5 1.8 2.4 2 0 0 2 2 2 0 PRA1 family protein Fungal_trans PF04082.18 EPS25265.1 - 3.7e-37 127.8 0.3 3.7e-37 127.8 0.3 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS25265.1 - 7.9e-08 32.3 14.7 1.3e-07 31.6 14.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_1 PF00170.21 EPS25265.1 - 0.088 12.9 1.3 0.21 11.7 0.1 2.2 2 0 0 2 2 2 0 bZIP transcription factor Cep57_MT_bd PF06657.13 EPS25265.1 - 0.11 12.9 2.0 12 6.4 0.2 2.6 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 HrpB7 PF09486.10 EPS25265.1 - 0.2 12.1 0.2 3.4 8.0 0.0 2.4 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Trimer_CC PF08954.11 EPS25265.1 - 0.27 10.8 1.8 0.57 9.8 0.7 2.1 2 0 0 2 2 2 0 Trimerisation motif SET PF00856.28 EPS25266.1 - 0.0074 16.7 0.0 0.013 15.9 0.0 1.6 1 0 0 1 1 1 1 SET domain L27_2 PF09045.10 EPS25266.1 - 0.024 14.6 1.2 0.055 13.4 0.0 2.1 2 1 0 2 2 2 0 L27_2 RFXA_RFXANK_bdg PF15289.6 EPS25266.1 - 0.091 13.1 0.2 0.23 11.8 0.2 1.6 1 0 0 1 1 1 0 Regulatory factor X-associated C-terminal binding domain MMR_HSR1_C PF08438.10 EPS25268.1 - 8.9e-36 122.9 0.0 1.5e-35 122.2 0.0 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 EPS25268.1 - 1.8e-20 73.2 0.0 4.1e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EPS25268.1 - 7.9e-09 35.2 0.1 1.6e-07 31.0 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 EPS25268.1 - 0.00046 19.8 0.0 0.099 12.2 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 EPS25268.1 - 0.018 14.8 0.1 4.4 7.0 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 EPS25268.1 - 0.02 15.0 1.3 0.14 12.2 0.2 2.5 3 0 0 3 3 3 0 Dynamin family MMR_HSR1_Xtn PF16897.5 EPS25268.1 - 0.049 13.7 0.1 0.13 12.3 0.1 1.7 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Ploopntkinase3 PF18751.1 EPS25268.1 - 0.056 13.3 0.0 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 KTI12 PF08433.10 EPS25268.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Amidohydro_2 PF04909.14 EPS25269.1 - 0.027 14.3 0.0 0.03 14.1 0.0 1.0 1 0 0 1 1 1 0 Amidohydrolase Ribosomal_L7Ae PF01248.26 EPS25273.1 - 3.2e-20 71.7 1.7 2.4e-19 68.8 1.7 2.3 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Spore_III_AF PF09581.10 EPS25273.1 - 0.11 12.5 11.9 1.3 9.0 6.9 2.1 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) Ndc1_Nup PF09531.10 EPS25273.1 - 0.26 9.9 0.4 0.24 10.0 0.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4050 PF13259.6 EPS25273.1 - 0.32 11.3 2.5 0.46 10.8 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) PPL5 PF18168.1 EPS25273.1 - 1.5 8.1 5.8 2.3 7.4 5.8 1.3 1 0 0 1 1 1 0 Prim-pol family 5 AAA_13 PF13166.6 EPS25273.1 - 1.7 7.2 8.9 2.2 6.8 8.9 1.1 1 0 0 1 1 1 0 AAA domain AP3D1 PF06375.11 EPS25273.1 - 3 8.0 15.8 0.74 10.0 10.8 2.2 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 NPR3 PF03666.13 EPS25273.1 - 3.5 6.3 7.3 25 3.5 0.0 2.0 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 MAD PF05557.13 EPS25274.1 - 5.1e-60 203.6 76.8 1.5e-51 175.6 77.9 2.1 2 0 0 2 2 2 2 Mitotic checkpoint protein DASH_Dam1 PF08653.10 EPS25274.1 - 9.8 6.1 6.1 1.1e+02 2.7 0.0 4.7 4 1 1 5 5 5 0 DASH complex subunit Dam1 muHD PF10291.9 EPS25275.1 - 9.6e-81 271.1 0.0 1.8e-80 270.2 0.0 1.5 2 0 0 2 2 2 1 Muniscin C-terminal mu homology domain FCH PF00611.23 EPS25275.1 - 9.7e-09 35.4 0.1 1.8e-07 31.4 0.0 2.9 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain DUF1202 PF06717.11 EPS25275.1 - 0.0088 15.5 0.1 0.014 14.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1202) BPL_N PF09825.9 EPS25275.1 - 0.15 11.1 0.1 0.26 10.3 0.1 1.3 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal COG2 PF06148.11 EPS25275.1 - 0.29 11.2 2.0 1.3 9.2 0.7 2.5 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Pkinase PF00069.25 EPS25276.1 - 1.5e-39 135.9 0.0 2.3e-39 135.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS25276.1 - 5.9e-13 48.7 0.0 9e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KIX_2 PF16987.5 EPS25276.1 - 3.1e-08 33.5 0.7 5.4e-08 32.7 0.7 1.4 1 0 0 1 1 1 1 KIX domain APH PF01636.23 EPS25276.1 - 9.1e-06 25.8 2.3 0.017 15.1 0.4 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EPS25276.1 - 0.00017 20.5 0.1 0.00045 19.1 0.1 1.9 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EPS25276.1 - 0.0077 15.6 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EPS25276.1 - 0.012 15.0 0.1 0.046 13.1 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 EPS25276.1 - 0.021 14.4 0.0 0.039 13.5 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF3813 PF12758.7 EPS25276.1 - 0.91 9.9 4.6 1.1 9.6 2.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3813) SH3_9 PF14604.6 EPS25277.1 - 3.2e-09 36.5 0.0 5.1e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EPS25277.1 - 4.6e-06 26.1 0.0 7.1e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 SH3 domain Podoplanin PF05808.11 EPS25277.1 - 0.0032 17.6 12.8 0.0032 17.6 12.8 2.4 2 0 0 2 2 2 1 Podoplanin CYYR1 PF10873.8 EPS25277.1 - 0.0075 16.7 0.1 0.0075 16.7 0.1 3.4 4 0 0 4 4 4 1 Cysteine and tyrosine-rich protein 1 DUF4366 PF14283.6 EPS25277.1 - 0.041 13.9 0.0 0.041 13.9 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4366) OPT PF03169.15 EPS25278.1 - 1e-178 595.9 12.9 1.2e-178 595.7 12.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Acetyltransf_1 PF00583.25 EPS25279.1 - 0.081 13.2 0.0 0.26 11.5 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Acyltransferase PF01553.21 EPS25281.1 - 1.9e-09 37.2 0.0 2.1e-08 33.9 0.0 2.3 1 1 0 1 1 1 1 Acyltransferase Rav1p_C PF12234.8 EPS25284.1 - 5e-286 950.2 0.2 7.1e-286 949.8 0.2 1.2 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.32 EPS25284.1 - 0.002 18.9 4.4 0.6 11.1 0.0 5.2 5 0 0 5 5 5 1 WD domain, G-beta repeat DUF3943 PF13084.6 EPS25284.1 - 0.054 13.3 0.1 0.18 11.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3943) Sfi1 PF08457.10 EPS25285.1 - 2.7e-208 693.1 89.3 2.7e-208 693.1 89.3 2.2 1 1 1 2 2 2 2 Sfi1 spindle body protein NDUF_B7 PF05676.13 EPS25286.1 - 0.00075 19.2 2.4 0.59 9.9 0.5 2.1 1 1 1 2 2 2 2 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CX9C PF16860.5 EPS25286.1 - 0.00077 19.4 0.6 0.00099 19.1 0.6 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 EPS25286.1 - 0.031 14.3 3.3 0.098 12.7 3.3 1.6 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Rota_NSP4 PF01452.16 EPS25286.1 - 0.056 13.1 0.5 0.057 13.1 0.5 1.0 1 0 0 1 1 1 0 Rotavirus non structural protein CHCH PF06747.13 EPS25286.1 - 0.15 12.2 2.6 0.83 9.9 2.5 1.9 1 1 1 2 2 2 0 CHCH domain tRNA-synt_1 PF00133.22 EPS25287.1 - 9.7e-229 760.6 0.0 1.3e-228 760.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EPS25287.1 - 5.7e-25 88.0 0.0 2.2e-24 86.1 0.0 2.1 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EPS25287.1 - 8.9e-15 54.3 0.0 1.4e-05 24.0 0.0 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EPS25287.1 - 0.13 11.6 0.0 0.29 10.5 0.0 1.6 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Uso1_p115_head PF04869.14 EPS25288.1 - 2.7e-108 361.8 0.0 1e-107 359.9 0.0 2.1 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 EPS25288.1 - 9.2e-25 87.4 36.9 9.2e-25 87.4 36.9 5.3 1 1 2 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region Pox_A_type_inc PF04508.12 EPS25288.1 - 0.021 14.7 0.0 3.8 7.5 0.0 3.2 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat XRN_M PF17846.1 EPS25289.1 - 2e-148 495.1 3.1 1.1e-147 492.5 0.1 2.6 2 1 0 2 2 2 1 Xrn1 helical domain XRN_N PF03159.18 EPS25289.1 - 1.2e-101 339.2 3.3 5.9e-101 337.0 0.0 2.2 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.23 EPS25289.1 - 0.0013 18.7 1.1 0.0023 17.9 1.1 1.4 1 0 0 1 1 1 1 Zinc knuckle EPSP_synthase PF00275.20 EPS25290.1 - 1.3e-128 429.3 0.0 2e-128 428.7 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 EPS25290.1 - 3.4e-98 328.0 0.0 6e-98 327.2 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 EPS25290.1 - 1.6e-58 198.7 0.0 3.5e-58 197.6 0.0 1.6 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 EPS25290.1 - 2.2e-40 138.4 0.0 1.2e-39 135.9 0.0 2.1 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.11 EPS25290.1 - 1.8e-24 85.8 0.0 5.6e-24 84.2 0.0 2.0 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 EPS25290.1 - 1.9e-08 33.9 0.8 5.4e-08 32.5 0.2 2.1 2 0 0 2 2 2 1 Shikimate 5'-dehydrogenase C-terminal domain Fe-ADH_2 PF13685.6 EPS25290.1 - 3.1e-07 30.3 0.0 6.9e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.20 EPS25290.1 - 0.00047 20.2 0.0 0.0013 18.9 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_24 PF13479.6 EPS25290.1 - 0.026 14.3 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sacchrp_dh_NADP PF03435.18 EPS25290.1 - 0.055 13.7 0.0 0.22 11.8 0.0 2.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain AAA_33 PF13671.6 EPS25290.1 - 0.17 12.1 0.0 0.4 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Fe-ADH PF00465.19 EPS25290.1 - 0.29 9.9 2.5 1.1 8.0 2.5 1.9 1 1 0 1 1 1 0 Iron-containing alcohol dehydrogenase p450 PF00067.22 EPS25291.1 - 3.4e-59 200.8 0.0 4.5e-59 200.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF5004 PF16395.5 EPS25292.1 - 0.027 14.5 0.1 0.027 14.5 0.1 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF5004) OAD_gamma PF04277.13 EPS25293.1 - 0.15 12.7 1.9 0.4 11.3 1.9 1.7 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Polyketide_cyc2 PF10604.9 EPS25294.1 - 0.11 12.8 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport zf-C2H2 PF00096.26 EPS25297.1 - 3.6e-10 39.7 13.8 0.00014 22.1 1.4 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPS25297.1 - 3.8e-06 27.3 10.7 0.027 15.3 1.1 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EPS25297.1 - 0.06 13.8 7.7 17 6.0 1.1 3.7 3 0 0 3 3 3 0 Zinc-finger double domain ig PF00047.25 EPS25297.1 - 0.14 12.4 1.2 0.2 11.9 0.0 1.9 2 0 0 2 2 2 0 Immunoglobulin domain zf-BED PF02892.15 EPS25297.1 - 0.34 11.0 2.0 0.81 9.8 2.0 1.6 1 0 0 1 1 1 0 BED zinc finger Big_2 PF02368.18 EPS25297.1 - 0.67 9.9 3.3 1.4 8.9 3.3 1.5 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 2) zf-Di19 PF05605.12 EPS25297.1 - 0.96 9.8 6.6 0.86 9.9 1.5 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_11 PF16622.5 EPS25297.1 - 1.8 8.4 4.7 1.6 8.5 0.5 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_3rep PF18868.1 EPS25297.1 - 9 7.0 6.9 9.9 6.9 0.0 3.3 3 1 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats F-box PF00646.33 EPS25298.1 - 4.4e-05 23.3 0.3 0.00011 22.0 0.3 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EPS25298.1 - 6e-05 22.9 0.6 0.00012 21.9 0.6 1.5 1 0 0 1 1 1 1 F-box-like CENP-T_C PF15511.6 EPS25299.1 - 8e-09 35.6 0.1 9.7e-09 35.3 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 EPS25299.1 - 2.4e-05 24.7 0.1 2.8e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 EPS25299.1 - 7.2e-05 22.9 0.1 0.0001 22.4 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EPS25299.1 - 0.0002 21.6 0.1 0.00035 20.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 EPS25299.1 - 0.0004 20.7 0.1 0.00056 20.2 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 EPS25299.1 - 0.0085 16.2 0.0 0.01 15.9 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EPS25299.1 - 0.031 14.3 0.0 0.037 14.0 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated UPF0137 PF03677.13 EPS25299.1 - 0.052 13.3 0.2 0.064 13.0 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) HIGH_NTase1_ass PF16581.5 EPS25299.1 - 0.11 12.5 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Histone PF00125.24 EPS25300.1 - 1e-51 174.7 2.5 1.1e-51 174.6 2.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EPS25300.1 - 6e-06 26.6 0.0 9e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EPS25300.1 - 4.9e-05 23.4 0.5 7.4e-05 22.8 0.1 1.5 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold PAF PF15715.5 EPS25300.1 - 6.5e-05 23.5 1.2 7.7e-05 23.3 1.2 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CBFD_NFYB_HMF PF00808.23 EPS25300.1 - 0.0032 17.7 0.3 0.0065 16.7 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EPS25300.1 - 0.026 14.6 0.2 0.042 13.9 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit MFS_1 PF07690.16 EPS25303.1 - 6.9e-40 137.1 49.5 1.3e-39 136.2 44.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS25303.1 - 2.1e-09 36.7 8.1 2.1e-09 36.7 8.1 2.8 1 1 1 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 EPS25303.1 - 0.016 13.6 4.5 3.2 5.9 0.7 3.1 2 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Mpv17_PMP22 PF04117.12 EPS25304.1 - 4.2e-16 58.9 0.7 4.2e-16 58.9 0.7 2.1 2 0 0 2 2 2 1 Mpv17 / PMP22 family Exo5 PF09810.9 EPS25305.1 - 9.4e-140 466.3 0.0 1.2e-139 466.0 0.0 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 EPS25305.1 - 0.013 15.5 0.1 3.3 7.6 0.0 3.3 4 0 0 4 4 4 0 PD-(D/E)XK nuclease superfamily DUF3799 PF12684.7 EPS25305.1 - 0.026 14.3 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 PDDEXK-like domain of unknown function (DUF3799) DUF3445 PF11927.8 EPS25306.1 - 2e-82 276.2 0.0 2.4e-82 275.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Glyco_transf_22 PF03901.17 EPS25307.1 - 1.2e-84 285.0 15.5 1.4e-84 284.8 15.5 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Gar1 PF04410.14 EPS25308.1 - 6.8e-45 152.6 0.4 6.8e-45 152.6 0.4 1.8 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region Cwf_Cwc_15 PF04889.12 EPS25308.1 - 4.3 7.0 18.3 2 8.1 11.2 2.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PRP3 PF08572.10 EPS25309.1 - 3e-73 246.3 8.2 3e-73 246.3 8.2 1.6 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 EPS25309.1 - 1.3e-45 155.0 0.0 1.3e-45 155.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) RNA_pol_Rpb1_5 PF04998.17 EPS25310.1 - 2.5e-84 282.9 0.1 4.5e-84 282.0 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EPS25310.1 - 1.6e-67 226.9 0.0 3e-67 226.0 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EPS25310.1 - 5.5e-32 110.9 0.0 3.5e-31 108.3 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 EPS25310.1 - 9.4e-28 97.4 2.0 1.4e-22 80.4 0.0 3.1 3 0 0 3 3 3 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 EPS25310.1 - 4e-17 62.1 0.3 3.3e-16 59.2 0.0 2.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 DEAD_2 PF06733.15 EPS25311.1 - 6.6e-53 178.9 0.4 6.6e-53 178.9 0.4 1.6 2 0 0 2 2 2 1 DEAD_2 HBB PF06777.11 EPS25311.1 - 2.7e-50 170.7 3.4 3.1e-45 154.2 0.6 2.7 3 0 0 3 3 3 2 Helical and beta-bridge domain Helicase_C_2 PF13307.6 EPS25311.1 - 8.7e-44 149.7 0.0 2.1e-43 148.4 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.15 EPS25311.1 - 0.00012 22.1 0.1 0.0066 16.5 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EPS25311.1 - 0.0037 17.1 0.0 0.27 11.0 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase PhoH PF02562.16 EPS25311.1 - 0.0052 16.3 0.3 2.3 7.6 0.0 3.3 3 0 0 3 3 3 1 PhoH-like protein SNF2_N PF00176.23 EPS25311.1 - 0.092 11.4 0.0 1.6 7.4 0.0 2.2 1 1 0 1 1 1 0 SNF2 family N-terminal domain zf-RING_2 PF13639.6 EPS25312.1 - 9.4e-08 32.3 9.0 2e-07 31.2 9.0 1.6 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 EPS25312.1 - 6.5e-05 23.0 6.2 0.00014 22.0 6.2 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 EPS25312.1 - 0.00016 21.6 2.2 0.00034 20.6 2.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EPS25312.1 - 0.00019 21.6 8.0 0.00044 20.5 8.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EPS25312.1 - 0.00057 19.7 11.7 0.00079 19.3 9.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EPS25312.1 - 0.0044 16.8 8.4 0.01 15.7 8.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 EPS25312.1 - 0.17 12.1 7.6 0.39 10.9 7.6 1.7 1 0 0 1 1 1 0 RING-variant domain C1_1 PF00130.22 EPS25312.1 - 0.21 11.5 5.8 0.47 10.4 5.8 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_11 PF17123.5 EPS25312.1 - 0.27 11.0 2.9 0.58 9.9 2.9 1.6 1 0 0 1 1 1 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 EPS25312.1 - 0.27 10.9 6.2 0.57 9.8 6.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 EPS25312.1 - 0.59 10.5 8.2 1.1 9.6 8.2 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 EPS25312.1 - 0.72 9.7 8.5 5.6 6.9 0.5 2.9 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 EPS25312.1 - 1 9.3 5.7 2.2 8.2 5.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 EPS25312.1 - 2.6 8.0 7.2 4.8 7.2 7.2 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_UBOX PF13445.6 EPS25312.1 - 2.8 8.0 5.7 6.4 6.9 5.7 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 EPS25312.1 - 4.5 7.2 6.2 11 5.9 6.2 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 LCM PF04072.14 EPS25313.1 - 2.7e-23 82.9 0.0 5e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Na_H_Exchanger PF00999.21 EPS25314.1 - 1.6e-35 122.6 34.0 2.6e-35 121.9 34.0 1.3 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family SUN PF03856.13 EPS25315.1 - 1.3e-81 273.7 7.2 1.3e-81 273.7 7.2 1.5 2 0 0 2 2 2 1 Beta-glucosidase (SUN family) SOG2 PF10428.9 EPS25315.1 - 1.8 7.6 28.9 2.8 7.1 28.9 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 EPS25315.1 - 2.9 7.7 15.9 4.4 7.1 15.9 1.3 1 0 0 1 1 1 0 SPX domain Glypican PF01153.19 EPS25315.1 - 8.3 5.1 9.1 12 4.5 9.1 1.2 1 0 0 1 1 1 0 Glypican adh_short PF00106.25 EPS25316.1 - 3.2e-13 49.6 0.0 3.9e-12 46.0 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EPS25316.1 - 0.041 13.8 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 KR domain FMN_bind_2 PF04299.12 EPS25318.1 - 1.1e-59 200.9 0.1 1.3e-59 200.6 0.1 1.0 1 0 0 1 1 1 1 Putative FMN-binding domain B_solenoid_ydck PF18836.1 EPS25318.1 - 0.12 12.3 0.1 0.28 11.1 0.1 1.7 1 0 0 1 1 1 0 Beta solenoid repeat from YDCK Ist1 PF03398.14 EPS25319.1 - 1.9e-42 145.0 5.4 1.2e-20 74.1 5.0 2.7 2 1 1 3 3 3 2 Regulator of Vps4 activity in the MVB pathway MSA-2c PF12238.8 EPS25319.1 - 0.042 13.9 0.0 0.042 13.9 0.0 2.0 2 0 0 2 2 2 0 Merozoite surface antigen 2c DUF4114 PF13448.6 EPS25320.1 - 0.0086 16.8 0.0 0.015 16.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4114) Clat_adaptor_s PF01217.20 EPS25321.1 - 8.8e-56 187.8 2.0 1e-55 187.6 2.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Sulfotransfer_4 PF17784.1 EPS25322.1 - 6.5e-73 245.1 0.0 8.5e-73 244.7 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EPS25322.1 - 6.5e-05 23.4 0.0 0.004 17.6 0.0 2.4 1 1 1 2 2 2 1 Sulfotransferase family Arylsulfotran_2 PF14269.6 EPS25323.1 - 1.4e-58 198.6 6.4 1.9e-58 198.2 6.4 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 EPS25323.1 - 7.6e-17 61.3 8.5 9.4e-15 54.4 8.5 3.0 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) MFS_1 PF07690.16 EPS25325.1 - 8.4e-15 54.5 47.8 4.2e-14 52.3 16.3 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TP_methylase PF00590.20 EPS25327.1 - 1.5e-24 87.1 0.3 2.5e-24 86.4 0.3 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases TFIID-18kDa PF02269.16 EPS25328.1 - 4.2e-25 87.6 0.3 4.2e-24 84.4 0.1 2.2 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit TAFII28 PF04719.14 EPS25328.1 - 0.011 15.8 0.0 0.023 14.8 0.0 1.6 1 0 0 1 1 1 0 hTAFII28-like protein conserved region E7 PF00527.18 EPS25328.1 - 0.83 9.9 2.6 1.3 9.3 0.7 2.0 2 0 0 2 2 2 0 E7 protein, Early protein Pyrid_ox_like PF16242.5 EPS25329.1 - 7.6e-21 74.3 0.0 1.4e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase like Putative_PNPOx PF01243.20 EPS25329.1 - 2.3e-08 34.1 0.0 4e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase FMN_bind_2 PF04299.12 EPS25329.1 - 0.065 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Putative FMN-binding domain F-box-like PF12937.7 EPS25330.1 - 5.9e-05 22.9 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EPS25330.1 - 0.00062 19.6 0.6 0.0027 17.5 0.0 2.2 2 0 0 2 2 2 1 F-box domain zf-C2H2_jaz PF12171.8 EPS25331.1 - 4.5e-08 33.2 0.5 7.2e-08 32.5 0.5 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EPS25331.1 - 3e-05 24.3 0.4 4.7e-05 23.6 0.4 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 EPS25331.1 - 0.0091 16.4 0.4 0.016 15.6 0.4 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type DUF3340 PF11818.8 EPS25331.1 - 1.6 8.9 16.0 2.8 8.1 7.3 2.1 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) BIR PF00653.21 EPS25332.1 - 1.3e-47 160.3 6.6 2.1e-24 86.0 0.1 2.6 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain DUF3525 PF12039.8 EPS25332.1 - 5.5 5.6 7.9 2 7.0 4.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3525) Tam41_Mmp37 PF09139.11 EPS25333.1 - 2.1e-129 431.6 0.0 2.6e-129 431.3 0.0 1.1 1 0 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial Aminotran_1_2 PF00155.21 EPS25334.1 - 2.5e-62 211.1 0.0 3.1e-62 210.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EPS25334.1 - 0.22 10.0 0.1 0.53 8.8 0.0 1.6 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Flavi_glycoprot PF00869.20 EPS25336.1 - 0.097 11.9 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Flavivirus glycoprotein, central and dimerisation domains RNA_pol_Rpb5_C PF01191.19 EPS25337.1 - 3.9e-34 116.4 0.1 8.2e-34 115.3 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 EPS25337.1 - 2.9e-28 98.3 0.0 4.4e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 EPS25337.1 - 0.057 13.4 0.0 0.11 12.5 0.0 1.6 1 1 0 1 1 1 0 Restriction endonuclease Myb_DNA-bind_4 PF13837.6 EPS25337.1 - 0.1 13.0 0.3 0.27 11.6 0.2 1.7 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain EzrA PF06160.12 EPS25338.1 - 0.00034 18.9 15.3 0.00034 18.9 15.3 3.4 2 1 0 3 3 3 3 Septation ring formation regulator, EzrA ABC_tran_CTD PF16326.5 EPS25338.1 - 0.0004 20.6 6.4 0.0004 20.6 6.4 5.8 3 3 1 5 5 5 1 ABC transporter C-terminal domain CENP-F_leu_zip PF10473.9 EPS25338.1 - 0.016 15.2 5.1 0.016 15.2 5.1 4.6 2 2 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2315 PF10231.9 EPS25338.1 - 8.6 6.5 13.3 17 5.5 0.8 3.0 2 0 0 2 2 2 0 Apoptogenic protein 1 Zw10 PF06248.13 EPS25338.1 - 9.8 4.6 19.1 0.2 10.2 9.3 2.5 2 1 1 3 3 3 0 Centromere/kinetochore Zw10 BCMA-Tall_bind PF09257.10 EPS25339.1 - 1.2 9.3 4.5 0.3 11.2 1.1 1.7 2 0 0 2 2 2 0 BCMA, TALL-1 binding CYSTM PF12734.7 EPS25340.1 - 1.1 9.7 72.1 1.8e+04 -16.4 72.1 4.9 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance HHH_3 PF12836.7 EPS25342.1 - 0.065 13.5 0.0 0.09 13.0 0.0 1.2 1 0 0 1 1 1 0 Helix-hairpin-helix motif Alpha-L-AF_C PF06964.12 EPS25343.1 - 5.1e-25 88.5 0.0 9.3e-25 87.7 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain NmrA PF05368.13 EPS25345.1 - 3e-17 63.0 0.0 4.2e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPS25345.1 - 1e-14 54.9 0.0 1.5e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EPS25345.1 - 3.1e-07 30.7 0.0 5.7e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EPS25345.1 - 2.7e-06 27.0 0.1 4e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 EPS25345.1 - 0.00029 21.0 0.1 0.00053 20.1 0.1 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 EPS25345.1 - 0.00033 21.1 0.1 0.00084 19.8 0.1 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 EPS25345.1 - 0.001 19.9 0.1 0.0018 19.1 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_4 PF07993.12 EPS25345.1 - 0.0017 17.5 0.9 0.015 14.5 0.1 2.2 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 EPS25345.1 - 0.0018 17.3 0.0 0.003 16.6 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 EPS25345.1 - 0.041 13.8 0.1 0.071 13.0 0.1 1.4 1 0 0 1 1 1 0 KR domain TrkA_N PF02254.18 EPS25345.1 - 0.057 13.7 0.2 0.14 12.5 0.1 1.7 2 0 0 2 2 2 0 TrkA-N domain Ldh_1_N PF00056.23 EPS25345.1 - 0.088 12.9 0.2 0.17 12.0 0.2 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.17 EPS25345.1 - 0.091 11.8 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain PglD_N PF17836.1 EPS25345.1 - 0.25 12.0 0.7 0.65 10.7 0.1 2.1 3 0 0 3 3 2 0 PglD N-terminal domain MFS_1 PF07690.16 EPS25346.1 - 4.3e-33 114.7 25.0 4.3e-33 114.7 25.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 EPS25346.1 - 0.00018 20.9 7.7 0.00018 20.9 7.7 2.9 1 1 1 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF4079 PF13301.6 EPS25346.1 - 0.34 11.1 6.1 0.91 9.7 2.7 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF4079) adh_short PF00106.25 EPS25347.1 - 6.7e-22 77.9 0.2 1.1e-21 77.2 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS25347.1 - 5e-16 59.0 0.5 6.6e-16 58.6 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EPS25347.1 - 1.1e-07 31.6 0.1 1.4e-07 31.3 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EPS25347.1 - 3.4e-07 30.3 0.4 5e-07 29.8 0.4 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EPS25347.1 - 3.3e-05 23.9 0.2 4.3e-05 23.5 0.2 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Acetate_kinase PF00871.17 EPS25347.1 - 0.053 12.2 0.0 0.073 11.8 0.0 1.1 1 0 0 1 1 1 0 Acetokinase family FlgT_N PF16548.5 EPS25347.1 - 0.1 13.2 1.1 0.2 12.3 1.1 1.5 1 0 0 1 1 1 0 Flagellar assembly protein T, N-terminal domain CAT_RBD PF03123.15 EPS25347.1 - 0.14 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 CAT RNA binding domain AA_permease PF00324.21 EPS25348.1 - 5e-108 361.7 42.6 6.2e-108 361.4 42.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EPS25348.1 - 8.6e-27 94.0 46.8 1.1e-26 93.7 46.8 1.1 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_35 PF01301.19 EPS25349.1 - 9.3e-98 327.7 0.0 1.4e-97 327.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.9 EPS25349.1 - 5.1e-66 221.9 0.4 9.4e-64 214.5 0.2 2.3 2 0 0 2 2 2 2 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.6 EPS25349.1 - 5.1e-59 197.8 8.8 1.7e-33 115.6 0.3 3.0 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.6 EPS25349.1 - 1.2e-23 82.5 0.0 4.7e-23 80.5 0.0 2.0 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Fve PF09259.11 EPS25349.1 - 0.023 14.8 0.1 0.085 13.0 0.1 1.9 1 0 0 1 1 1 0 Fungal immunomodulatory protein Fve Methyltr_RsmB-F PF01189.17 EPS25350.1 - 9e-31 107.1 0.0 3e-24 85.8 0.0 3.1 2 1 0 2 2 2 2 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 EPS25350.1 - 0.14 12.2 0.0 0.28 11.3 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase Peptidase_M16 PF00675.20 EPS25351.1 - 7.1e-56 188.3 0.1 1.5e-55 187.3 0.1 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EPS25351.1 - 2.1e-39 135.5 0.0 2.1e-37 128.9 0.0 2.3 2 0 0 2 2 2 2 Peptidase M16 inactive domain Epimerase PF01370.21 EPS25352.1 - 2.1e-19 69.9 0.0 2.7e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EPS25352.1 - 6.7e-15 54.8 0.0 8.6e-15 54.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EPS25352.1 - 1.3e-11 44.5 0.0 1.6e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EPS25352.1 - 5.4e-06 25.7 0.0 7.8e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 EPS25352.1 - 0.0036 16.8 0.0 0.0072 15.8 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPS25352.1 - 0.0056 16.6 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EPS25352.1 - 0.016 14.4 0.0 0.045 12.9 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EPS25352.1 - 0.03 14.2 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding NAD_binding_4 PF07993.12 EPS25352.1 - 0.033 13.4 0.3 1.3 8.1 0.3 2.5 1 1 0 1 1 1 0 Male sterility protein Soyouz_module PF14313.6 EPS25352.1 - 0.062 13.1 0.1 0.64 9.8 0.0 2.2 2 0 0 2 2 2 0 N-terminal region of Paramyxovirinae phosphoprotein (P) Fibrillarin PF01269.17 EPS25353.1 - 3.7e-103 343.5 0.0 4.2e-103 343.3 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 EPS25353.1 - 8.5e-06 25.6 0.0 1.5e-05 24.8 0.0 1.3 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 EPS25353.1 - 0.0028 17.5 0.1 0.0041 16.9 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF3455 PF11937.8 EPS25354.1 - 1e-45 156.0 0.1 1.3e-45 155.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.8 EPS25354.1 - 4.8e-27 93.9 1.3 1.4e-26 92.5 1.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2990) CASP_C PF08172.12 EPS25355.1 - 5e-89 298.0 0.4 5e-89 298.0 0.4 4.2 2 1 3 5 5 5 1 CASP C terminal ZapB PF06005.12 EPS25355.1 - 0.099 13.1 0.1 0.099 13.1 0.1 6.9 5 2 0 5 5 5 0 Cell division protein ZapB Ly49 PF08391.10 EPS25355.1 - 3.3 8.1 16.1 7.5 6.9 0.1 4.1 3 1 1 4 4 4 0 Ly49-like protein, N-terminal region SlyX PF04102.12 EPS25355.1 - 6.5 7.5 0.0 6.5 7.5 0.0 6.7 6 1 1 7 7 7 0 SlyX K_channel_TID PF07941.11 EPS25355.1 - 8.7 6.9 9.8 17 5.9 6.3 2.6 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Vps39_2 PF10367.9 EPS25356.1 - 1.3e-05 25.6 0.0 3.8e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 EPS25356.1 - 0.0053 17.0 0.1 0.056 13.7 0.0 2.6 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 BNIP3 PF06553.12 EPS25356.1 - 0.04 13.6 0.1 0.083 12.6 0.1 1.4 1 0 0 1 1 1 0 BNIP3 LSM PF01423.22 EPS25357.1 - 1.6e-21 75.8 0.2 1.9e-21 75.5 0.2 1.1 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.6 EPS25357.1 - 0.013 16.1 7.5 0.019 15.5 7.5 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 DUF150_C PF17384.2 EPS25357.1 - 0.028 14.6 0.0 0.048 13.8 0.0 1.3 1 0 0 1 1 1 0 RimP C-terminal SH3 domain Zn_clus PF00172.18 EPS25358.1 - 0.048 13.8 9.7 0.1 12.7 9.7 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Dioxygenase_C PF00775.21 EPS25359.1 - 2e-41 141.4 0.0 2.7e-41 141.0 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 EPS25359.1 - 5.3e-31 106.3 0.0 9.3e-31 105.5 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 EPS25359.1 - 0.026 14.8 0.0 0.094 13.0 0.0 1.9 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain Pan3_PK PF18101.1 EPS25360.1 - 1.2e-63 213.2 0.4 1.8e-63 212.6 0.4 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 EPS25360.1 - 1.6e-06 27.7 0.0 2.8e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS25360.1 - 0.0047 16.2 0.0 0.0073 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_4 PF14555.6 EPS25361.1 - 3.3e-11 42.8 0.0 6.7e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 EPS25361.1 - 2.2e-10 40.6 0.0 4e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 UBX domain Atg14 PF10186.9 EPS25361.1 - 0.13 11.3 8.7 0.2 10.7 8.7 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 YlqD PF11068.8 EPS25361.1 - 0.7 10.3 5.5 1.3 9.4 5.5 1.4 1 0 0 1 1 1 0 YlqD protein Presenilin PF01080.17 EPS25361.1 - 6.6 5.4 4.7 9.5 4.9 4.7 1.1 1 0 0 1 1 1 0 Presenilin DDRGK PF09756.9 EPS25361.1 - 8.7 5.9 15.4 14 5.2 15.4 1.2 1 0 0 1 1 1 0 DDRGK domain ABC2_membrane PF01061.24 EPS25362.1 - 2.8e-88 294.8 62.4 4.3e-48 163.5 23.5 3.4 4 0 0 4 4 3 2 ABC-2 type transporter PDR_CDR PF06422.12 EPS25362.1 - 3.1e-38 129.5 7.2 2.3e-34 117.1 0.0 3.4 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.27 EPS25362.1 - 1.5e-37 129.2 0.0 8.9e-18 65.1 0.0 2.9 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.6 EPS25362.1 - 4.6e-19 68.8 0.1 1.4e-18 67.2 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 EPS25362.1 - 3.8e-06 26.9 0.2 0.00057 19.8 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EPS25362.1 - 5.2e-06 26.9 0.1 0.0017 18.8 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 EPS25362.1 - 4.1e-05 23.2 0.1 0.00036 20.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 EPS25362.1 - 0.00016 20.9 17.5 0.00016 20.9 17.5 3.1 2 1 1 3 3 3 1 ABC-2 family transporter protein AAA_33 PF13671.6 EPS25362.1 - 0.00035 20.8 0.0 0.015 15.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EPS25362.1 - 0.00068 19.3 1.2 0.027 14.2 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EPS25362.1 - 0.0013 18.6 0.0 2.8 7.7 0.1 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 EPS25362.1 - 0.0054 17.3 0.0 0.11 13.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 EPS25362.1 - 0.0065 15.9 0.0 0.5 9.8 0.0 3.1 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain RNA_helicase PF00910.22 EPS25362.1 - 0.012 16.0 0.1 4.9 7.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.6 EPS25362.1 - 0.014 15.7 0.7 1.2 9.4 0.1 2.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EPS25362.1 - 0.023 14.6 2.0 3.9 7.4 0.2 3.2 3 0 0 3 3 3 0 NACHT domain IstB_IS21 PF01695.17 EPS25362.1 - 0.1 12.4 0.1 3.7 7.3 0.0 2.6 3 0 0 3 3 2 0 IstB-like ATP binding protein cobW PF02492.19 EPS25362.1 - 0.12 12.0 0.5 0.57 9.7 0.1 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 EPS25362.1 - 0.14 11.9 1.8 4.5 7.0 0.5 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EPS25362.1 - 0.15 12.1 0.0 33 4.6 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_17 PF13207.6 EPS25362.1 - 0.18 12.2 0.2 5.2 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain PDR_assoc PF08370.11 EPS25362.1 - 2.8 7.7 6.8 1.9 8.3 0.2 3.3 3 0 0 3 3 3 0 Plant PDR ABC transporter associated zf-C2H2 PF00096.26 EPS25364.1 - 2.7e-06 27.5 8.5 0.00011 22.4 0.1 2.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPS25364.1 - 0.00032 21.3 8.1 0.046 14.6 0.1 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger Ferric_reduct PF01794.19 EPS25365.1 - 1.5e-24 86.5 10.5 3.3e-24 85.4 10.5 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EPS25365.1 - 1.1e-14 54.9 0.0 6.3e-09 36.1 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EPS25365.1 - 3.2e-11 43.3 0.1 1.2e-06 28.5 0.2 2.6 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.21 EPS25365.1 - 0.0053 17.4 0.0 0.021 15.5 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain adh_short_C2 PF13561.6 EPS25366.1 - 7.7e-54 182.7 0.1 9.5e-54 182.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPS25366.1 - 1.2e-49 168.5 0.0 2e-49 167.7 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EPS25366.1 - 1.3e-09 38.2 0.1 3.9e-09 36.7 0.0 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EPS25366.1 - 5.6e-07 29.3 0.0 7.4e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EPS25366.1 - 0.001 18.5 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase ADH_zinc_N PF00107.26 EPS25366.1 - 0.01 15.8 0.1 0.019 14.9 0.1 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase THF_DHG_CYH_C PF02882.19 EPS25366.1 - 0.02 14.2 0.4 0.062 12.6 0.2 1.8 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RmlD_sub_bind PF04321.17 EPS25366.1 - 0.023 13.8 0.1 0.099 11.7 0.0 2.0 2 1 0 2 2 2 0 RmlD substrate binding domain F420_oxidored PF03807.17 EPS25366.1 - 0.026 15.1 1.4 0.74 10.4 0.2 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.15 EPS25366.1 - 0.069 12.3 0.0 0.095 11.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_7 PF13241.6 EPS25366.1 - 0.1 13.1 0.1 0.32 11.4 0.1 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding Glyco_transf_5 PF08323.11 EPS25366.1 - 0.17 11.6 0.0 0.61 9.7 0.0 1.8 2 0 0 2 2 2 0 Starch synthase catalytic domain Fungal_trans PF04082.18 EPS25367.1 - 1e-11 44.4 0.0 5.9e-11 41.9 0.0 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS25367.1 - 5.4e-06 26.4 9.8 9.4e-06 25.7 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.6 EPS25368.1 - 1.2e-48 165.8 0.4 1.3e-48 165.6 0.4 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPS25368.1 - 1.6e-46 158.2 0.4 2.1e-46 157.9 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPS25368.1 - 1.2e-11 44.8 0.3 1.8e-11 44.2 0.3 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EPS25368.1 - 3.1e-06 26.8 0.2 4.2e-06 26.4 0.2 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EPS25368.1 - 7.6e-06 25.9 0.0 2e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EPS25368.1 - 3.9e-05 23.2 0.2 0.00011 21.7 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EPS25368.1 - 0.00012 21.3 0.0 0.00016 20.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 EPS25368.1 - 0.0003 21.1 0.0 0.00046 20.4 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain RmlD_sub_bind PF04321.17 EPS25368.1 - 0.045 12.8 0.1 0.081 12.0 0.1 1.4 1 1 0 1 1 1 0 RmlD substrate binding domain DNA_gyraseA_C PF03989.13 EPS25368.1 - 0.16 11.5 0.0 0.62 9.6 0.0 2.0 2 0 0 2 2 2 0 DNA gyrase C-terminal domain, beta-propeller NAD_synthase PF02540.17 EPS25368.1 - 0.16 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 NAD synthase ADH_N PF08240.12 EPS25369.1 - 1.9e-26 92.1 1.0 3.3e-26 91.3 1.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 EPS25369.1 - 8.2e-13 48.3 0.4 1.2e-05 24.9 0.0 2.2 2 0 0 2 2 2 2 Glucose dehydrogenase C-terminus ADH_zinc_N PF00107.26 EPS25369.1 - 1.3e-11 44.6 0.0 5.4e-11 42.6 0.0 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 EPS25369.1 - 0.0089 16.3 0.2 0.016 15.5 0.2 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 EPS25369.1 - 0.038 13.7 0.0 0.064 12.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ADH_zinc_N_2 PF13602.6 EPS25369.1 - 0.058 14.5 0.0 0.11 13.5 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EPS25370.1 - 7.4e-56 188.3 0.0 9.6e-56 187.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EPS25370.1 - 3.3e-18 65.6 0.0 3.9e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EPS25370.1 - 0.0015 18.7 0.1 0.0048 17.1 0.1 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.21 EPS25370.1 - 0.048 13.7 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Ribosomal_L22 PF00237.19 EPS25371.1 - 5.8e-42 142.1 0.1 8.6e-42 141.6 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e HAD_2 PF13419.6 EPS25373.1 - 5.7e-10 39.6 0.0 1.5e-09 38.2 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EPS25373.1 - 0.0078 16.5 0.0 0.33 11.2 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase GAT PF03127.14 EPS25374.1 - 2.4e-16 59.8 0.6 6.3e-16 58.4 0.6 1.7 1 0 0 1 1 1 1 GAT domain VHS PF00790.19 EPS25374.1 - 0.001 18.9 0.0 0.0022 17.9 0.0 1.5 1 0 0 1 1 1 1 VHS domain LPMO_10 PF03067.15 EPS25375.1 - 5.8e-14 53.2 0.6 9.7e-14 52.5 0.6 1.4 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Serglycin PF04360.12 EPS25375.1 - 0.025 14.5 1.4 0.044 13.7 1.4 1.4 1 0 0 1 1 1 0 Serglycin Herpes_capsid PF06112.11 EPS25375.1 - 0.54 10.3 10.9 1.2 9.2 10.9 1.7 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Cation_efflux PF01545.21 EPS25376.1 - 9.3e-13 48.4 9.2 1.2e-12 48.0 9.2 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EPS25376.1 - 1.4e-10 41.2 0.2 4.5e-10 39.5 0.2 1.8 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Pectate_lyase_3 PF12708.7 EPS25377.1 - 1.9e-101 338.4 21.9 3.8e-87 291.6 5.0 3.4 4 0 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EPS25377.1 - 4.6e-08 32.6 2.4 0.00063 19.4 0.1 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Aminotran_1_2 PF00155.21 EPS25380.1 - 1.2e-12 47.7 0.0 1.6e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Ank_2 PF12796.7 EPS25382.1 - 2.5e-51 172.2 0.1 2e-15 57.1 0.0 4.5 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.30 EPS25382.1 - 1.4e-41 139.1 5.1 3.4e-07 30.4 0.1 8.2 9 0 0 9 9 9 6 Ankyrin repeat Ank_4 PF13637.6 EPS25382.1 - 2.8e-38 129.8 10.7 1.6e-13 50.8 0.5 7.3 4 2 4 8 8 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPS25382.1 - 4.4e-38 124.9 2.5 1.8e-05 24.8 0.0 9.4 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 EPS25382.1 - 5.8e-33 112.5 8.8 8.2e-08 32.4 0.1 7.5 2 2 5 7 7 7 6 Ankyrin repeats (many copies) CorA PF01544.18 EPS25382.1 - 5.7e-15 55.4 0.6 1.4e-14 54.1 0.6 1.6 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF4870 PF09685.10 EPS25382.1 - 0.17 12.0 0.8 0.31 11.2 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4870) Kdo PF06293.14 EPS25384.1 - 1.6e-06 27.6 0.3 2.3e-06 27.1 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EPS25384.1 - 6.9e-05 22.9 0.1 0.039 13.9 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 EPS25384.1 - 0.0054 16.1 0.0 0.0071 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 EPS25384.1 - 0.027 14.1 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 RIO1 family WaaY PF06176.11 EPS25384.1 - 0.094 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Choline_kinase PF01633.20 EPS25384.1 - 0.1 12.1 0.0 6.1 6.4 0.0 2.1 1 1 1 2 2 2 0 Choline/ethanolamine kinase FMN_dh PF01070.18 EPS25385.1 - 4.1e-107 358.2 0.0 5.4e-107 357.8 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EPS25385.1 - 4.3e-20 71.6 0.0 1.1e-19 70.4 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EPS25385.1 - 6.4e-05 22.2 0.1 0.00018 20.8 0.0 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase IMPDH PF00478.25 EPS25385.1 - 0.00015 20.9 0.1 0.00065 18.8 0.0 2.0 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EPS25385.1 - 0.099 12.0 0.7 0.23 10.8 0.1 1.8 2 0 0 2 2 2 0 Nitronate monooxygenase Fungal_trans_2 PF11951.8 EPS25386.1 - 2.9e-20 72.4 11.6 5.1e-18 65.0 11.6 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS25386.1 - 1.8e-05 24.7 11.0 4.1e-05 23.6 11.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhyH PF05721.13 EPS25387.1 - 2.6e-24 86.7 0.0 3.3e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) AA_permease PF00324.21 EPS25388.1 - 4.7e-141 470.7 45.8 5.7e-141 470.4 45.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EPS25388.1 - 7.1e-34 117.4 52.2 9.1e-34 117.0 52.2 1.1 1 0 0 1 1 1 1 Amino acid permease HSP20 PF00011.21 EPS25389.1 - 1.3e-08 34.9 0.1 2.7e-08 33.9 0.1 1.6 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EPS25389.1 - 0.027 14.0 0.0 0.091 12.3 0.0 1.9 1 1 0 1 1 1 0 HSP20-like domain found in ArsA GRP PF07172.11 EPS25389.1 - 0.18 12.5 10.4 0.38 11.5 10.4 1.5 1 0 0 1 1 1 0 Glycine rich protein family Pyr_redox_2 PF07992.14 EPS25390.1 - 2.6e-36 125.4 0.0 1.1e-33 116.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPS25390.1 - 6.7e-10 39.4 0.0 3.8e-07 30.6 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPS25390.1 - 0.016 15.4 0.0 3.8 7.8 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Amidase PF01425.21 EPS25391.1 - 1.6e-93 314.2 0.0 2.1e-93 313.8 0.0 1.1 1 0 0 1 1 1 1 Amidase adh_short_C2 PF13561.6 EPS25392.1 - 3.3e-44 151.2 0.7 4e-44 150.9 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPS25392.1 - 4.4e-40 137.2 0.3 6.2e-40 136.7 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPS25392.1 - 2.8e-10 40.4 0.3 4.2e-10 39.8 0.3 1.2 1 0 0 1 1 1 1 KR domain Sod_Fe_C PF02777.18 EPS25393.1 - 1.9e-33 114.7 0.2 4.8e-33 113.4 0.0 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EPS25393.1 - 3.9e-33 113.7 2.8 3.9e-33 113.7 2.8 1.9 2 1 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain SR-25 PF10500.9 EPS25394.1 - 1.6 8.3 10.1 2.1 7.9 10.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF515 PF04415.12 EPS25394.1 - 9.4 4.5 7.1 12 4.2 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) TFIID-31kDa PF02291.15 EPS25395.1 - 2.6e-46 156.7 0.0 3.6e-46 156.2 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Mucin PF01456.17 EPS25395.1 - 0.84 9.6 12.7 0.058 13.4 7.3 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein Cmc1 PF08583.10 EPS25396.1 - 2.2e-15 56.4 8.0 5.1e-15 55.2 8.0 1.7 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 EPS25396.1 - 0.0077 16.2 0.3 0.015 15.3 0.3 1.4 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, eIF3_N PF09440.10 EPS25396.1 - 0.81 10.1 4.9 0.84 10.1 4.4 1.3 1 1 0 1 1 1 0 eIF3 subunit 6 N terminal domain Utp11 PF03998.13 EPS25397.1 - 1.1e-60 205.6 26.1 1.4e-60 205.3 26.1 1.1 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 EPS25397.1 - 0.031 13.6 1.0 0.035 13.4 0.1 1.5 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Inhibitor_I71 PF12628.7 EPS25397.1 - 0.39 10.6 1.8 0.46 10.3 0.6 1.7 2 0 0 2 2 2 0 Falstatin, cysteine peptidase inhibitor CIAPIN1 PF05093.13 EPS25398.1 - 1.1e-41 141.3 3.3 1.1e-41 141.3 3.3 1.7 2 0 0 2 2 2 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 EPS25398.1 - 1.2e-37 129.1 0.1 1.7e-37 128.6 0.1 1.3 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus Histidinol_dh PF00815.20 EPS25399.1 - 2.9e-159 530.5 4.2 2.9e-159 530.5 4.2 1.7 2 0 0 2 2 2 1 Histidinol dehydrogenase PRA-CH PF01502.18 EPS25399.1 - 6e-24 83.7 0.2 1.4e-23 82.5 0.2 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 EPS25399.1 - 2.4e-13 50.3 0.4 7.5e-13 48.7 0.4 1.8 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase Glyco_hydro_47 PF01532.20 EPS25400.1 - 1.6e-138 462.4 0.0 1.9e-138 462.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 TPKR_C2 PF16920.5 EPS25400.1 - 0.092 12.9 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Tyrosine-protein kinase receptor C2 Ig-like domain TPR_2 PF07719.17 EPS25401.1 - 2.4e-14 52.2 8.7 0.00025 20.9 0.1 5.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 EPS25401.1 - 1.9e-09 36.9 9.9 0.0037 17.0 0.1 5.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 EPS25401.1 - 8.4e-07 28.6 1.4 1.5 8.6 0.1 5.4 5 0 0 5 5 5 2 TPR repeat TPR_12 PF13424.6 EPS25401.1 - 2.1e-06 27.9 5.0 8.1e-05 22.8 0.3 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EPS25401.1 - 7.2e-06 26.5 14.3 0.00057 20.5 0.4 5.5 4 1 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 EPS25401.1 - 1.7e-05 24.7 0.9 0.43 10.9 0.0 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EPS25401.1 - 0.00053 20.5 9.6 0.04 14.4 0.2 5.5 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EPS25401.1 - 0.0012 19.5 0.3 0.0012 19.5 0.3 5.4 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 EPS25401.1 - 0.0018 18.2 2.7 1.9 8.7 0.2 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EPS25401.1 - 0.0089 16.2 0.4 1.7 8.9 0.1 3.3 1 1 2 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EPS25401.1 - 0.036 14.5 7.5 6.8 7.3 0.0 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.6 EPS25401.1 - 0.11 12.4 7.1 3.3 7.7 0.4 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EPS25401.1 - 7.2 7.5 14.3 0.26 12.0 0.5 5.1 6 1 0 6 6 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 EPS25401.1 - 9.2 7.2 18.8 1.1 10.1 1.1 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat LNS2 PF08235.13 EPS25402.1 - 6.9e-95 316.8 0.0 9.8e-95 316.3 0.0 1.2 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 EPS25402.1 - 1.6e-42 143.6 0.0 3.2e-42 142.7 0.0 1.5 1 0 0 1 1 1 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 EPS25402.1 - 0.0019 17.9 0.0 0.086 12.4 0.0 2.8 3 0 0 3 3 3 1 HAD superfamily, subfamily IIIB (Acid phosphatase) fn3 PF00041.21 EPS25403.1 - 6.3e-07 29.6 0.0 1.7e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain Macoilin PF09726.9 EPS25403.1 - 0.00073 18.2 19.1 0.00073 18.2 19.1 2.3 3 0 0 3 3 3 1 Macoilin family DUF2400 PF09674.10 EPS25403.1 - 0.039 14.0 2.5 0.09 12.8 2.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) Takusan PF04822.13 EPS25403.1 - 2.9 7.8 12.2 8.7 6.3 12.2 1.8 1 0 0 1 1 1 0 Takusan Thg1 PF04446.12 EPS25404.1 - 2.1e-51 173.1 0.0 3.3e-51 172.6 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 EPS25404.1 - 4.9e-51 172.0 2.8 6.6e-51 171.6 2.8 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Peptidase_C48 PF02902.19 EPS25406.1 - 5e-14 52.7 0.4 2.8e-13 50.2 0.4 2.1 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF4951 PF16309.5 EPS25406.1 - 0.069 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Domian of unknown function (DUF4951) WH2 PF02205.20 EPS25407.1 - 8.4e-06 25.4 1.3 2.4e-05 24.0 1.3 1.8 1 0 0 1 1 1 1 WH2 motif LSM PF01423.22 EPS25408.1 - 2.3e-16 59.2 0.2 3.3e-16 58.7 0.2 1.2 1 0 0 1 1 1 1 LSM domain RecQ5 PF06959.11 EPS25410.1 - 0.034 14.1 1.7 0.32 10.9 0.3 2.3 2 0 0 2 2 2 0 RecQ helicase protein-like 5 (RecQ5) SURF4 PF02077.15 EPS25411.1 - 3.3e-94 315.4 7.1 3.7e-94 315.3 7.1 1.0 1 0 0 1 1 1 1 SURF4 family DoxX PF07681.12 EPS25411.1 - 0.083 13.5 19.8 0.29 11.7 0.3 3.3 3 2 0 3 3 3 0 DoxX Atg14 PF10186.9 EPS25412.1 - 7.8 5.5 10.0 0.94 8.5 6.0 1.4 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 IU_nuc_hydro PF01156.19 EPS25414.1 - 1.7e-58 198.6 0.0 2.6e-58 198.0 0.0 1.2 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Transketolase_C PF02780.20 EPS25414.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Transketolase, C-terminal domain FAP PF07174.11 EPS25415.1 - 0.0088 15.5 1.6 0.011 15.2 1.6 1.0 1 0 0 1 1 1 1 Fibronectin-attachment protein (FAP) HLH PF00010.26 EPS25416.1 - 1.4e-13 50.6 0.2 2.7e-13 49.6 0.2 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MFS_1 PF07690.16 EPS25419.1 - 1.8e-24 86.3 38.1 1.6e-17 63.5 8.4 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS25419.1 - 5.4e-08 32.1 1.9 5.4e-08 32.1 1.9 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EPS25419.1 - 2.2e-07 29.7 0.5 2.2e-07 29.7 0.5 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Zn_clus PF00172.18 EPS25421.1 - 1.4e-05 25.1 8.7 2.6e-05 24.2 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC_membrane PF00664.23 EPS25422.1 - 1.7e-83 280.4 23.4 1.3e-42 146.4 4.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EPS25422.1 - 8.8e-65 217.4 0.0 3.7e-31 108.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EPS25422.1 - 5.6e-13 48.8 7.3 0.00019 21.0 1.4 4.7 3 2 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EPS25422.1 - 3.1e-08 34.0 0.7 0.077 13.3 0.0 4.0 3 1 0 3 3 3 2 AAA domain ABC_ATPase PF09818.9 EPS25422.1 - 3.5e-07 29.4 1.1 0.014 14.3 0.0 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.6 EPS25422.1 - 5e-07 29.4 0.1 0.036 13.8 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EPS25422.1 - 5.2e-07 30.2 0.8 0.0051 17.2 0.1 3.2 2 2 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.17 EPS25422.1 - 4.8e-05 23.6 0.0 0.12 12.5 0.0 2.7 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_30 PF13604.6 EPS25422.1 - 0.00013 21.8 1.0 0.23 11.2 0.0 3.9 4 1 0 4 4 4 1 AAA domain AAA_21 PF13304.6 EPS25422.1 - 0.00013 21.9 2.2 0.5 10.1 0.0 3.5 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EPS25422.1 - 0.00041 20.3 0.0 0.61 10.0 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_5 PF07728.14 EPS25422.1 - 0.00059 19.8 0.0 4 7.5 0.0 4.2 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 EPS25422.1 - 0.0014 19.1 0.0 3.1 8.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 EPS25422.1 - 0.0033 17.2 0.0 1.9 8.1 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain SRP54 PF00448.22 EPS25422.1 - 0.0035 17.0 0.1 0.37 10.4 0.0 3.2 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain Rad17 PF03215.15 EPS25422.1 - 0.004 17.1 0.0 2.5 8.0 0.0 2.3 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_24 PF13479.6 EPS25422.1 - 0.0062 16.3 0.0 4.4 7.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EPS25422.1 - 0.016 15.5 0.1 9.5 6.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 EPS25422.1 - 0.023 14.8 0.0 7.3 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF3987 PF13148.6 EPS25422.1 - 0.027 13.5 0.0 4.5 6.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) G-alpha PF00503.20 EPS25422.1 - 0.028 13.6 0.0 1.1 8.3 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit Zeta_toxin PF06414.12 EPS25422.1 - 0.043 13.1 0.0 1.9 7.7 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin AAA_25 PF13481.6 EPS25422.1 - 0.046 13.3 0.0 13 5.3 0.0 3.3 3 0 0 3 3 3 0 AAA domain PRK PF00485.18 EPS25422.1 - 0.051 13.3 0.0 13 5.5 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EPS25422.1 - 0.056 14.0 0.0 13 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain MTH865 PF07747.11 EPS25422.1 - 0.11 12.3 0.0 1.8 8.4 0.0 2.5 3 0 0 3 3 2 0 MTH865-like family AAA_7 PF12775.7 EPS25422.1 - 0.11 11.9 0.0 17 4.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region SbcCD_C PF13558.6 EPS25422.1 - 0.11 12.7 7.9 6.4 7.1 0.2 4.6 4 2 0 4 4 2 0 Putative exonuclease SbcCD, C subunit RSV_NS2 PF03113.14 EPS25423.1 - 0.18 11.8 0.0 0.31 11.1 0.0 1.3 1 0 0 1 1 1 0 Respiratory synctial virus non-structural protein NS2 CLASP_N PF12348.8 EPS25424.1 - 8.5e-147 486.7 0.2 1.2e-84 283.4 0.0 2.2 2 0 0 2 2 2 2 CLASP N terminal Cnd1 PF12717.7 EPS25424.1 - 1e-06 28.9 0.0 0.051 13.6 0.1 3.6 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EPS25424.1 - 5e-05 23.2 1.0 9.8 6.8 0.0 5.6 6 0 0 6 6 6 1 HEAT repeat Adaptin_N PF01602.20 EPS25424.1 - 0.021 13.4 0.6 0.098 11.2 0.1 2.2 2 1 0 2 2 2 0 Adaptin N terminal region DUF4704 PF15787.5 EPS25424.1 - 0.077 12.2 0.7 0.92 8.7 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4704) Cohesin_HEAT PF12765.7 EPS25424.1 - 0.079 13.3 0.6 2.1 8.7 0.0 3.0 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion DUF3361 PF11841.8 EPS25424.1 - 0.16 11.9 0.1 0.71 9.8 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3361) BSP PF04450.12 EPS25425.1 - 7.7e-72 241.4 0.0 9.1e-72 241.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase of plants and bacteria Ribonucleas_3_3 PF14622.6 EPS25426.1 - 9.6e-07 29.0 0.0 0.0018 18.4 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EPS25426.1 - 5.1e-06 27.1 0.0 2.6e-05 24.8 0.0 2.1 1 1 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.26 EPS25426.1 - 2.2e-05 25.1 0.0 5.2e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif PfkB PF00294.24 EPS25428.1 - 2.5e-12 46.7 0.0 7.7e-12 45.1 0.0 1.7 1 1 0 1 1 1 1 pfkB family carbohydrate kinase CAP_N PF01213.19 EPS25429.1 - 3e-113 378.5 10.5 2.7e-111 372.1 10.5 2.3 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 EPS25429.1 - 2e-58 196.4 1.8 2.9e-58 195.9 1.8 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 EPS25429.1 - 0.025 14.3 1.9 0.97 9.2 1.3 2.2 1 1 1 2 2 2 0 Tubulin binding cofactor C Exonuc_VII_S PF02609.16 EPS25429.1 - 0.12 12.5 0.1 0.29 11.2 0.1 1.7 1 0 0 1 1 1 0 Exonuclease VII small subunit DUF4210 PF13915.6 EPS25430.1 - 4.3e-32 110.5 0.1 1.3e-31 109.0 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.6 EPS25430.1 - 2.5e-24 85.2 0.5 5.3e-24 84.1 0.5 1.6 1 0 0 1 1 1 1 Chromosome segregation during meiosis rRNA_processing PF08524.11 EPS25431.1 - 0.17 11.9 22.8 4.9 7.2 22.8 2.1 1 1 0 1 1 1 0 rRNA processing RR_TM4-6 PF06459.12 EPS25431.1 - 8.2 6.2 8.5 11 5.7 8.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sec5 PF15469.6 EPS25432.1 - 1.2e-36 126.3 0.1 5.4e-36 124.2 0.0 2.3 3 0 0 3 3 3 1 Exocyst complex component Sec5 Vps51 PF08700.11 EPS25432.1 - 2.8e-06 27.3 0.7 8.6e-06 25.7 0.1 2.2 2 0 0 2 2 2 1 Vps51/Vps67 DUF4111 PF13427.6 EPS25432.1 - 0.068 13.3 0.1 0.42 10.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4111) COG2 PF06148.11 EPS25432.1 - 0.095 12.8 0.1 0.37 10.9 0.1 2.0 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF445 PF04286.12 EPS25432.1 - 0.29 10.9 5.0 14 5.3 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF445) Iso_dh PF00180.20 EPS25433.1 - 6.8e-101 337.9 0.0 8.2e-101 337.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HHH_2 PF12826.7 EPS25433.1 - 0.067 13.3 0.0 0.54 10.4 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif Eaf7 PF07904.13 EPS25434.1 - 3.1e-29 101.4 1.4 3.2e-29 101.4 0.1 1.7 2 0 0 2 2 2 1 Chromatin modification-related protein EAF7 Nop14 PF04147.12 EPS25434.1 - 1.1 7.3 11.0 1.6 6.9 11.0 1.2 1 0 0 1 1 1 0 Nop14-like family LAP1C PF05609.12 EPS25434.1 - 2.8 6.9 7.9 4.1 6.4 7.9 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) GCP_C_terminal PF04130.13 EPS25435.1 - 9.5e-70 235.5 0.1 2.6e-69 234.1 0.0 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EPS25435.1 - 3.3e-41 141.9 0.2 7.6e-41 140.7 0.2 1.7 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal Mo-co_dimer PF03404.16 EPS25436.1 - 4e-58 195.3 0.1 7.1e-58 194.5 0.1 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.19 EPS25436.1 - 3e-55 186.5 0.0 5.4e-55 185.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.24 EPS25436.1 - 7.1e-35 119.3 0.0 1.2e-34 118.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EPS25436.1 - 6e-31 107.3 0.1 1.7e-30 105.9 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 EPS25436.1 - 3.1e-17 62.5 0.0 5.7e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 EPS25436.1 - 0.0031 17.6 0.1 0.43 10.7 0.0 2.3 1 1 1 2 2 2 1 Ferric reductase NAD binding domain Pyr_redox_2 PF07992.14 EPS25437.1 - 3e-43 148.2 0.3 6.2e-43 147.1 0.3 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NIR_SIR PF01077.22 EPS25437.1 - 3e-22 78.8 0.0 6.6e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox PF00070.27 EPS25437.1 - 9.6e-16 58.1 0.5 9.6e-16 58.1 0.5 3.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.6 EPS25437.1 - 3.3e-15 55.9 0.0 6.9e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Fer2_BFD PF04324.15 EPS25437.1 - 6.4e-15 55.2 9.3 3.6e-13 49.6 5.4 2.9 3 0 0 3 3 2 2 BFD-like [2Fe-2S] binding domain Rieske PF00355.26 EPS25437.1 - 6.1e-14 51.7 0.1 4e-13 49.1 0.0 2.3 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.17 EPS25437.1 - 1.6e-09 37.4 0.0 3.7e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Rubredoxin_C PF18267.1 EPS25437.1 - 2.8e-06 27.2 0.2 0.0088 15.9 0.0 3.0 3 0 0 3 3 3 2 Rubredoxin NAD+ reductase C-terminal domain NAD_binding_9 PF13454.6 EPS25437.1 - 0.0067 16.4 0.3 3.9 7.4 0.1 3.4 3 1 1 4 4 4 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 EPS25437.1 - 0.06 12.5 0.0 3.9 6.5 0.0 2.4 1 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 EPS25437.1 - 0.14 11.2 0.5 0.47 9.5 0.0 2.0 3 0 0 3 3 3 0 FAD binding domain MFS_1 PF07690.16 EPS25438.1 - 3.2e-27 95.4 27.4 3.2e-27 95.4 27.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily rhaM PF05336.13 EPS25439.1 - 4.5e-38 129.6 0.1 5.1e-38 129.5 0.1 1.0 1 0 0 1 1 1 1 L-rhamnose mutarotase DUF2794 PF10984.8 EPS25439.1 - 0.077 13.1 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2794) His_Phos_1 PF00300.22 EPS25440.1 - 2.4e-30 105.7 0.0 3.3e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) GNAT_acetyltr_2 PF13718.6 EPS25440.1 - 0.14 11.5 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Ribosomal_L5e PF17144.4 EPS25441.1 - 8e-81 269.8 0.8 8e-81 269.8 0.8 1.5 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 EPS25441.1 - 9.3e-35 119.5 10.3 9.3e-35 119.5 10.3 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Colicin_immun PF09204.10 EPS25441.1 - 0.052 14.1 1.0 0.052 14.1 1.0 2.4 3 1 0 3 3 3 0 Bacterial self-protective colicin-like immunity Thr_synth_N PF14821.6 EPS25441.1 - 0.12 12.6 0.2 13 6.1 0.0 2.7 3 0 0 3 3 3 0 Threonine synthase N terminus HAD_2 PF13419.6 EPS25442.1 - 5.8e-07 29.8 0.0 8e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EPS25442.1 - 0.00022 21.6 0.0 0.00029 21.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EPS25442.1 - 0.0018 18.3 0.0 0.003 17.6 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.7 EPS25442.1 - 0.18 11.7 0.0 0.28 11.0 0.0 1.2 1 0 0 1 1 1 0 Acid Phosphatase FTA4 PF13093.6 EPS25443.1 - 9.6e-61 205.2 4.2 1.1e-60 204.9 4.2 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Wtap PF17098.5 EPS25444.1 - 0.022 14.7 2.0 0.066 13.1 2.0 1.9 1 1 0 1 1 1 0 WTAP/Mum2p family DEC-1_N PF04625.13 EPS25444.1 - 0.056 12.5 0.5 0.098 11.7 0.5 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region SIKE PF05769.11 EPS25444.1 - 0.32 10.9 10.8 0.43 10.5 10.8 1.2 1 0 0 1 1 1 0 SIKE family SlyX PF04102.12 EPS25444.1 - 0.71 10.5 3.1 0.64 10.7 0.3 2.5 3 0 0 3 3 3 0 SlyX LRR_4 PF12799.7 EPS25445.1 - 0.074 13.5 4.9 32 5.1 0.4 5.4 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EPS25445.1 - 0.32 11.7 5.9 96 4.2 0.1 6.0 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_6 PF13516.6 EPS25445.1 - 0.65 10.2 9.8 12 6.2 0.0 5.7 6 0 0 6 6 6 0 Leucine Rich repeat Cas9_b_hairpin PF17893.1 EPS25446.1 - 0.01 15.6 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated endonuclease Cas9 beta-hairpin domain DUF349 PF03993.12 EPS25446.1 - 0.14 12.5 0.9 0.18 12.2 0.5 1.4 1 1 0 1 1 1 0 Domain of Unknown Function (DUF349) DUF2718 PF10918.8 EPS25447.1 - 0.027 15.0 0.0 0.062 13.8 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2718) ABC_tran PF00005.27 EPS25450.1 - 7.5e-51 172.2 0.4 6e-28 98.1 0.3 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EPS25450.1 - 1.1e-27 97.4 33.0 1.6e-22 80.5 12.7 2.9 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_22 PF13401.6 EPS25450.1 - 4.3e-09 36.8 1.7 0.0017 18.7 0.0 3.5 2 2 0 2 2 2 2 AAA domain SMC_N PF02463.19 EPS25450.1 - 5.7e-09 35.7 5.6 0.0014 18.1 2.6 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EPS25450.1 - 5.4e-08 32.9 1.2 0.00031 20.7 0.1 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 EPS25450.1 - 6.5e-08 32.7 0.8 0.15 11.9 0.0 3.5 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EPS25450.1 - 1.6e-07 31.9 0.2 0.013 15.9 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 EPS25450.1 - 2.1e-07 31.0 1.5 0.004 17.2 0.1 3.0 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_7 PF12775.7 EPS25450.1 - 6.1e-07 29.1 0.8 0.011 15.3 0.1 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region NB-ARC PF00931.22 EPS25450.1 - 1.2e-06 27.9 0.0 0.0011 18.2 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain AAA PF00004.29 EPS25450.1 - 2.2e-06 28.2 0.2 0.037 14.4 0.0 3.1 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 EPS25450.1 - 2e-05 24.2 3.5 0.092 12.5 0.4 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SSE PF00437.20 EPS25450.1 - 0.00014 21.0 1.9 0.11 11.6 0.1 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_30 PF13604.6 EPS25450.1 - 0.00034 20.4 0.4 0.34 10.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain TsaE PF02367.17 EPS25450.1 - 0.00045 20.2 0.4 0.79 9.7 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EPS25450.1 - 0.00054 20.1 0.1 0.28 11.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 EPS25450.1 - 0.00072 20.1 1.4 1.3 9.5 0.5 2.4 2 0 0 2 2 2 2 AAA domain cobW PF02492.19 EPS25450.1 - 0.00081 19.0 4.3 0.31 10.6 0.6 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Mg_chelatase PF01078.21 EPS25450.1 - 0.001 18.5 0.1 0.94 8.8 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EPS25450.1 - 0.001 19.4 0.1 0.86 10.0 0.0 3.5 3 0 0 3 3 2 1 RNA helicase ATPase_2 PF01637.18 EPS25450.1 - 0.0013 18.7 1.2 0.68 9.8 0.0 3.5 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea Septin PF00735.18 EPS25450.1 - 0.004 16.5 1.5 0.13 11.5 0.2 2.2 2 0 0 2 2 2 1 Septin PduV-EutP PF10662.9 EPS25450.1 - 0.0057 16.4 1.7 1 9.1 0.1 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation IstB_IS21 PF01695.17 EPS25450.1 - 0.0061 16.3 1.9 10 5.8 0.0 4.2 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_11 PF13086.6 EPS25450.1 - 0.0069 16.2 1.2 4.9 6.8 0.1 3.2 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 EPS25450.1 - 0.007 16.4 1.1 4 7.4 0.1 3.4 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 EPS25450.1 - 0.0082 16.1 3.5 1.7 8.5 0.2 3.1 3 0 0 3 3 2 1 NACHT domain SbcCD_C PF13558.6 EPS25450.1 - 0.011 16.0 0.2 4 7.7 0.0 3.0 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.23 EPS25450.1 - 0.014 15.5 1.5 1 9.4 0.1 2.4 2 0 0 2 2 2 0 Dynamin family AAA_25 PF13481.6 EPS25450.1 - 0.018 14.6 0.2 1.9 8.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 EPS25450.1 - 0.019 14.7 1.1 5.4 6.6 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Viral_helicase1 PF01443.18 EPS25450.1 - 0.02 14.6 0.9 2.1 8.0 0.1 3.0 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Roc PF08477.13 EPS25450.1 - 0.026 14.7 1.5 2.6 8.3 0.1 3.0 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 EPS25450.1 - 0.031 14.0 2.2 4.1 7.1 0.1 2.7 2 1 0 2 2 2 0 AAA domain DEAD PF00270.29 EPS25450.1 - 0.033 14.0 0.7 1.1 8.9 0.1 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase Zeta_toxin PF06414.12 EPS25450.1 - 0.033 13.5 0.2 6.1 6.1 0.1 3.3 3 0 0 3 3 3 0 Zeta toxin FtsK_SpoIIIE PF01580.18 EPS25450.1 - 0.035 13.4 1.4 2.3 7.5 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_18 PF13238.6 EPS25450.1 - 0.039 14.5 0.2 8.2 7.0 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EPS25450.1 - 0.052 13.6 0.5 1.6 8.8 0.0 3.4 3 0 0 3 3 3 0 AAA domain Adeno_IVa2 PF02456.15 EPS25450.1 - 0.061 12.1 0.2 0.13 11.0 0.0 1.5 2 0 0 2 2 1 0 Adenovirus IVa2 protein DUF87 PF01935.17 EPS25450.1 - 0.067 13.3 3.1 0.24 11.5 0.2 2.3 2 0 0 2 2 2 0 Helicase HerA, central domain ATP-synt_ab PF00006.25 EPS25450.1 - 0.071 12.8 0.2 9.8 5.8 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Sigma54_activat PF00158.26 EPS25450.1 - 0.072 12.8 0.0 10 5.8 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.6 EPS25450.1 - 0.074 13.4 2.7 3.2 8.1 0.4 2.9 2 1 0 2 2 2 0 AAA domain MobB PF03205.14 EPS25450.1 - 0.079 12.9 1.9 5.8 6.8 0.2 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Rad17 PF03215.15 EPS25450.1 - 0.1 12.5 0.6 0.42 10.5 0.1 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain GTP_EFTU PF00009.27 EPS25450.1 - 0.12 11.9 0.2 9 5.8 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF815 PF05673.13 EPS25450.1 - 0.15 11.2 0.1 14 4.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 EPS25450.1 - 0.32 10.9 7.1 2 8.3 0.3 2.7 3 0 0 3 3 2 0 NTPase Metallophos PF00149.28 EPS25451.1 - 0.00057 20.4 0.0 0.00069 20.2 0.0 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ABC_tran PF00005.27 EPS25452.1 - 2.5e-41 141.4 9.9 1.7e-20 73.9 0.2 3.9 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 EPS25452.1 - 2.9e-13 50.3 11.1 5e-05 23.3 0.5 4.3 4 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 EPS25452.1 - 8.5e-10 38.5 4.3 8.5e-10 38.5 4.3 2.5 2 0 0 2 2 1 1 ABC transporter SMC_N PF02463.19 EPS25452.1 - 7.5e-09 35.3 3.5 0.0023 17.4 0.1 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EPS25452.1 - 9e-05 22.1 2.4 0.0098 15.6 0.1 3.0 3 0 0 3 3 3 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EPS25452.1 - 9.1e-05 22.5 0.7 0.49 10.5 0.0 3.3 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_30 PF13604.6 EPS25452.1 - 0.00037 20.3 6.1 0.22 11.2 0.2 4.0 3 1 0 3 3 3 2 AAA domain AAA_28 PF13521.6 EPS25452.1 - 0.00077 19.7 3.4 0.33 11.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain DUF87 PF01935.17 EPS25452.1 - 0.0013 18.9 0.3 0.0013 18.9 0.3 2.9 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_22 PF13401.6 EPS25452.1 - 0.005 17.1 2.9 1.1 9.6 0.0 3.5 3 1 0 3 3 2 1 AAA domain MeaB PF03308.16 EPS25452.1 - 0.013 14.5 0.8 3.8 6.4 0.1 2.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 EPS25452.1 - 0.018 15.6 3.6 3.1 8.3 0.1 3.1 3 0 0 3 3 2 0 AAA domain AAA PF00004.29 EPS25452.1 - 0.021 15.2 1.7 1.4 9.3 0.0 3.4 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EPS25452.1 - 0.025 14.5 0.4 1.3 8.9 0.0 2.7 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.6 EPS25452.1 - 0.037 14.4 8.6 1.8 8.9 0.0 3.4 2 1 0 2 2 2 0 AAA ATPase domain MukB PF04310.12 EPS25452.1 - 0.076 12.8 0.4 0.36 10.6 0.1 2.4 2 0 0 2 2 2 0 MukB N-terminal TsaE PF02367.17 EPS25452.1 - 0.12 12.3 0.6 5 7.1 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 EPS25452.1 - 0.12 12.2 8.0 1.7 8.5 0.1 3.1 4 0 0 4 4 3 0 RsgA GTPase RNA_helicase PF00910.22 EPS25452.1 - 0.18 12.2 0.4 4 7.9 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.6 EPS25452.1 - 0.23 11.9 26.9 0.64 10.5 11.5 4.2 3 1 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 EPS25452.1 - 0.3 11.0 2.3 32 4.4 0.0 3.9 4 0 0 4 4 4 0 NTPase AAA_33 PF13671.6 EPS25452.1 - 7.7 6.7 11.5 13 6.0 1.2 4.3 4 1 0 4 4 4 0 AAA domain HSDR_N_2 PF13588.6 EPS25453.1 - 0.18 11.8 0.0 5.9 6.9 0.0 2.2 1 1 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) MoaC PF01967.21 EPS25456.1 - 7.5e-48 162.1 0.2 1.3e-47 161.3 0.2 1.4 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.13 EPS25456.1 - 5.8e-37 126.5 0.1 3.1e-36 124.1 0.0 2.1 1 1 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 EPS25456.1 - 7.5e-28 98.0 0.0 1.4e-27 97.1 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 EPS25456.1 - 4.4e-05 23.8 0.0 9.2e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Noc2 PF03715.13 EPS25457.1 - 2e-128 427.8 0.1 2e-128 427.8 0.1 1.9 2 0 0 2 2 2 1 Noc2p family Nop14 PF04147.12 EPS25457.1 - 0.026 12.8 0.0 0.026 12.8 0.0 3.2 2 1 0 3 3 3 0 Nop14-like family VPS28 PF03997.12 EPS25458.1 - 2.9e-72 242.3 0.0 3.4e-72 242.1 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein PLCC PF14466.6 EPS25458.1 - 0.15 12.1 0.0 0.27 11.4 0.0 1.3 1 0 0 1 1 1 0 PLAT/LH2 and C2-like Ca2+-binding lipoprotein Methyltransf_16 PF10294.9 EPS25460.1 - 5.2e-22 78.4 0.0 1e-21 77.4 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_25 PF13649.6 EPS25460.1 - 0.025 15.3 0.0 0.057 14.1 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EPS25460.1 - 0.24 11.2 0.0 0.83 9.4 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain DUF829 PF05705.14 EPS25461.1 - 2.8e-44 151.8 0.0 3.3e-44 151.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) IcmF_C PF06744.12 EPS25462.1 - 0.17 11.5 0.1 0.27 10.8 0.1 1.3 1 0 0 1 1 1 0 Type VI secretion protein IcmF C-terminal DEAD PF00270.29 EPS25463.1 - 2.4e-27 95.8 0.0 1.3e-26 93.4 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPS25463.1 - 1.4e-23 83.3 0.0 4.3e-23 81.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPS25463.1 - 4.7e-07 30.0 0.0 2.7e-06 27.5 0.0 2.1 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EPS25463.1 - 0.14 12.4 0.3 27 5.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain ATP-synt_G PF04718.15 EPS25464.1 - 3.9e-35 120.7 0.3 7.2e-35 119.8 0.1 1.6 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit ADH_N PF08240.12 EPS25465.1 - 4.3e-27 94.2 1.0 1e-26 92.9 1.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPS25465.1 - 1.1e-12 48.1 0.0 2e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EPS25465.1 - 0.00014 21.4 0.2 0.055 12.9 0.1 3.0 3 0 0 3 3 3 2 Glucose dehydrogenase C-terminus Glyco_hydro_31 PF01055.26 EPS25467.1 - 5.5e-163 543.2 1.2 6.8e-163 542.9 1.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 EPS25467.1 - 2.8e-32 111.3 0.0 5.3e-32 110.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 EPS25467.1 - 3.1e-13 49.8 1.3 3.1e-13 49.8 1.3 2.1 2 0 0 2 2 2 1 Galactose mutarotase-like MULE PF10551.9 EPS25467.1 - 0.21 12.0 0.0 0.44 11.0 0.0 1.5 1 0 0 1 1 1 0 MULE transposase domain Glyco_hydro_16 PF00722.21 EPS25468.1 - 4.1e-42 143.6 3.6 4.1e-42 143.6 3.6 2.2 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 RGI_lyase PF18370.1 EPS25468.1 - 0.094 13.0 0.1 0.094 13.0 0.1 2.1 2 0 0 2 2 2 0 Rhamnogalacturonan I lyases beta-sheet domain SOG2 PF10428.9 EPS25468.1 - 0.87 8.7 18.4 1.2 8.3 18.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein tRNA-synt_2b PF00587.25 EPS25470.1 - 1.1e-32 113.4 0.0 1.8e-32 112.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EPS25470.1 - 1.5e-05 25.0 0.0 2.6e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain HMGL-like PF00682.19 EPS25471.1 - 3e-80 269.6 0.0 6.4e-80 268.5 0.0 1.5 2 0 0 2 2 2 1 HMGL-like LeuA_dimer PF08502.10 EPS25471.1 - 1.1e-19 70.7 0.0 2.1e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain AMP-binding PF00501.28 EPS25472.1 - 1.3e-65 221.7 0.7 9.3e-37 126.6 0.0 4.0 2 2 0 2 2 2 2 AMP-binding enzyme DMAP_binding PF06464.11 EPS25472.1 - 9e-10 39.4 0.0 2.5e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.12 EPS25472.1 - 0.026 14.5 0.3 0.052 13.6 0.3 1.5 1 0 0 1 1 1 0 Gas vesicle protein G Ribosomal_S7 PF00177.21 EPS25473.1 - 3.3e-35 120.9 2.4 4.1e-35 120.6 2.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e SDA1 PF05285.12 EPS25474.1 - 1.8e-95 320.4 59.8 2.4e-95 319.9 50.6 3.1 2 1 0 2 2 2 1 SDA1 NUC130_3NT PF08158.12 EPS25474.1 - 8.7e-22 77.2 0.3 2.1e-21 76.0 0.3 1.7 1 0 0 1 1 1 1 NUC130/3NT domain Chordopox_A30L PF06015.12 EPS25474.1 - 3.6 7.5 6.6 19 5.2 6.6 2.3 1 0 0 1 1 1 0 Chordopoxvirus A30L protein RNR_inhib PF08591.10 EPS25475.1 - 2.2e-20 74.0 0.1 6.4e-20 72.4 0.1 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase inhibitor p450 PF00067.22 EPS25476.1 - 1.4e-60 205.4 0.0 1.9e-60 205.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HSP70 PF00012.20 EPS25479.1 - 1.1e-61 208.7 6.4 2e-59 201.4 0.2 3.5 4 0 0 4 4 4 2 Hsp70 protein Tubulin_3 PF14881.6 EPS25482.1 - 7.7e-87 289.7 0.8 1.1e-86 289.1 0.8 1.2 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 EPS25482.1 - 6.4e-44 149.0 0.0 1.3e-42 144.9 0.0 2.9 3 0 0 3 3 3 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 EPS25482.1 - 0.0012 19.1 0.0 0.59 10.3 0.0 2.4 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain AAL_decarboxy PF03306.13 EPS25483.1 - 0.2 10.9 0.0 0.4 10.0 0.0 1.4 1 0 0 1 1 1 0 Alpha-acetolactate decarboxylase Spc7 PF08317.11 EPS25483.1 - 0.42 9.5 22.6 0.097 11.5 17.4 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein AATF-Che1 PF13339.6 EPS25483.1 - 1.1 9.9 15.9 3.2 8.5 13.9 2.7 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor V_ATPase_I PF01496.19 EPS25483.1 - 2.3 6.0 7.1 3.6 5.4 7.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IFT57 PF10498.9 EPS25483.1 - 3.2 6.6 15.2 21 4.0 14.1 2.2 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF3584 PF12128.8 EPS25483.1 - 3.4 5.0 24.7 2.5 5.5 22.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) IMD PF08397.11 EPS25483.1 - 3.9 6.8 12.3 8.5 5.7 10.8 2.1 1 1 0 2 2 2 0 IRSp53/MIM homology domain FapA PF03961.13 EPS25483.1 - 5.1 5.6 11.9 6.2 5.3 10.9 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A Peptidase_S46 PF10459.9 EPS25483.1 - 5.6 5.5 10.3 8.4 4.9 10.3 1.2 1 0 0 1 1 1 0 Peptidase S46 ERM PF00769.19 EPS25483.1 - 8.9 6.0 36.9 51 3.6 36.8 2.2 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Ead_Ea22 PF13935.6 EPS25483.1 - 9.9 6.8 23.9 14 6.3 7.1 3.3 2 1 1 3 3 3 0 Ead/Ea22-like protein DUF2347 PF09804.9 EPS25484.1 - 1.5e-103 346.3 0.0 2e-103 345.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.6 EPS25484.1 - 2.4e-59 200.9 0.2 4.4e-59 200.1 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) Avl9 PF09794.9 EPS25484.1 - 0.014 14.1 0.0 7.7 5.1 0.0 2.5 2 1 1 3 3 3 0 Transport protein Avl9 SPA PF08616.10 EPS25484.1 - 0.059 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis EBP PF05241.12 EPS25485.1 - 1.5e-58 197.2 11.0 1.7e-58 197.0 11.0 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF3915 PF13054.6 EPS25486.1 - 3.5 7.6 5.8 8.8 6.3 5.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) SNF2_N PF00176.23 EPS25487.1 - 5.1e-58 196.5 0.0 8.1e-58 195.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EPS25487.1 - 8.3e-15 55.1 0.0 1.8e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPS25487.1 - 3.8e-09 36.8 0.0 7.2e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 EPS25487.1 - 0.052 13.2 0.0 0.091 12.4 0.0 1.4 1 0 0 1 1 1 0 SWI2/SNF2 ATPase Spt5_N PF11942.8 EPS25487.1 - 0.35 11.9 8.4 1.2 10.2 8.4 1.9 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal CDC45 PF02724.14 EPS25487.1 - 3.7 5.7 6.5 6.1 5.0 6.5 1.2 1 0 0 1 1 1 0 CDC45-like protein AA_permease_2 PF13520.6 EPS25488.1 - 4.8e-49 167.3 54.9 5.8e-49 167.1 54.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPS25488.1 - 4.5e-21 75.0 45.0 8.8e-21 74.0 45.0 1.3 1 1 0 1 1 1 1 Amino acid permease MerE PF05052.12 EPS25488.1 - 0.12 12.3 3.7 0.12 12.3 0.4 2.9 2 0 0 2 2 2 0 MerE protein EMC3_TMCO1 PF01956.16 EPS25489.1 - 0.87 9.3 6.6 4 7.2 0.4 2.4 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like DUF2721 PF11026.8 EPS25489.1 - 1.4 8.8 7.6 13 5.7 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) AAA_2 PF07724.14 EPS25491.1 - 3.4e-46 157.5 0.0 8.5e-45 152.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EPS25491.1 - 1.1e-33 115.2 2.3 1.1e-33 115.2 2.3 3.6 4 0 0 4 4 4 1 AAA lid domain AAA PF00004.29 EPS25491.1 - 7.1e-28 97.7 0.3 1.9e-14 54.2 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EPS25491.1 - 1.8e-23 82.4 0.2 6.1e-23 80.7 0.2 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 EPS25491.1 - 3.1e-15 56.4 0.0 4.1e-09 36.5 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EPS25491.1 - 2.4e-13 50.5 0.0 8.4e-05 22.9 0.0 4.2 2 1 1 3 3 3 2 AAA domain AAA_16 PF13191.6 EPS25491.1 - 1.7e-11 44.8 11.2 5.7e-07 30.1 0.1 5.2 5 1 0 5 5 4 2 AAA ATPase domain Sigma54_activat PF00158.26 EPS25491.1 - 6e-09 35.8 0.0 2.3e-05 24.1 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_18 PF13238.6 EPS25491.1 - 1.6e-06 28.7 0.2 0.064 13.8 0.0 4.0 3 1 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 EPS25491.1 - 2.3e-06 27.5 0.0 0.11 12.2 0.0 3.0 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_14 PF13173.6 EPS25491.1 - 2.5e-06 27.5 0.0 0.068 13.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 EPS25491.1 - 3.2e-06 26.8 0.0 0.018 14.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region TniB PF05621.11 EPS25491.1 - 8e-06 25.4 0.4 0.058 12.8 0.0 4.6 4 2 0 4 4 4 1 Bacterial TniB protein Mg_chelatase PF01078.21 EPS25491.1 - 1.4e-05 24.6 0.0 0.18 11.1 0.0 3.4 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EPS25491.1 - 2.8e-05 24.3 0.0 0.26 11.4 0.0 3.2 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EPS25491.1 - 7.3e-05 23.1 0.0 0.56 10.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase ABC_tran PF00005.27 EPS25491.1 - 9.7e-05 22.9 0.6 0.95 10.0 0.0 3.5 3 0 0 3 3 3 1 ABC transporter ATPase_2 PF01637.18 EPS25491.1 - 0.0002 21.4 5.6 0.11 12.4 0.3 4.4 5 1 0 5 5 3 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 EPS25491.1 - 0.00021 21.1 0.0 1.3 8.7 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_3 PF07726.11 EPS25491.1 - 0.00023 21.1 0.0 1 9.3 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 EPS25491.1 - 0.00029 20.8 0.0 0.29 11.2 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Clp_N PF02861.20 EPS25491.1 - 0.00034 20.7 1.0 5.9 7.1 0.0 4.0 3 0 0 3 3 3 0 Clp amino terminal domain, pathogenicity island component RsgA_GTPase PF03193.16 EPS25491.1 - 0.00036 20.5 0.0 0.42 10.5 0.0 2.8 2 0 0 2 2 2 1 RsgA GTPase AAA_28 PF13521.6 EPS25491.1 - 0.00063 20.0 4.6 0.58 10.4 0.0 3.6 3 1 0 3 3 2 2 AAA domain AAA_24 PF13479.6 EPS25491.1 - 0.00081 19.2 0.0 0.78 9.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 EPS25491.1 - 0.0014 18.4 3.9 2.5 7.8 0.8 4.5 3 2 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 EPS25491.1 - 0.0014 18.9 0.1 0.45 10.8 0.1 3.1 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EPS25491.1 - 0.0014 18.3 0.0 1.6 8.6 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain Roc PF08477.13 EPS25491.1 - 0.0036 17.5 0.0 1 9.6 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase T2SSE PF00437.20 EPS25491.1 - 0.0038 16.3 2.3 0.014 14.5 0.0 2.6 3 0 0 3 3 3 1 Type II/IV secretion system protein NTPase_1 PF03266.15 EPS25491.1 - 0.0059 16.5 0.0 0.16 11.9 0.0 2.9 3 0 0 3 3 3 1 NTPase NACHT PF05729.12 EPS25491.1 - 0.0072 16.3 0.0 0.47 10.4 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.6 EPS25491.1 - 0.013 15.1 2.9 0.46 10.0 0.0 3.2 3 0 0 3 3 3 0 AAA domain SRP54 PF00448.22 EPS25491.1 - 0.021 14.4 0.3 8.5 5.9 0.0 3.1 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain ResIII PF04851.15 EPS25491.1 - 0.024 14.7 0.0 3.8 7.5 0.0 3.3 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Torsin PF06309.11 EPS25491.1 - 0.038 14.1 0.0 0.17 12.0 0.0 2.0 2 0 0 2 2 1 0 Torsin Rad17 PF03215.15 EPS25491.1 - 0.081 12.8 0.0 13 5.7 0.0 2.6 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_23 PF13476.6 EPS25491.1 - 0.21 12.1 0.0 0.21 12.1 0.0 4.2 4 2 0 4 4 2 0 AAA domain YlqD PF11068.8 EPS25491.1 - 0.46 10.9 6.3 1.4 9.3 6.3 1.8 1 0 0 1 1 1 0 YlqD protein V_ATPase_I PF01496.19 EPS25491.1 - 0.49 8.2 2.3 0.74 7.7 2.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MPS2 PF17060.5 EPS25491.1 - 5.7 6.1 7.7 0.5 9.6 2.6 1.7 2 0 0 2 2 2 0 Monopolar spindle protein 2 Sulfotransfer_3 PF13469.6 EPS25493.1 - 0.0027 18.1 0.2 0.64 10.4 0.0 3.1 3 1 0 3 3 3 2 Sulfotransferase family ATG27 PF09451.10 EPS25494.1 - 3.9e-88 295.7 0.0 4.7e-88 295.5 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 EPS25494.1 - 6.8e-07 29.5 0.0 6.7e-05 23.0 0.0 2.6 3 0 0 3 3 3 1 Cation-independent mannose-6-phosphate receptor repeat Man-6-P_recep PF02157.15 EPS25494.1 - 0.053 12.6 0.0 0.39 9.8 0.0 2.1 2 0 0 2 2 2 0 Mannose-6-phosphate receptor DUF2207 PF09972.9 EPS25494.1 - 0.12 11.2 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Prefoldin_2 PF01920.20 EPS25495.1 - 6e-24 84.0 3.8 7.3e-24 83.8 3.8 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF5065 PF16723.5 EPS25495.1 - 0.041 14.0 0.1 0.061 13.4 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF5065) PEP-utilisers_N PF05524.13 EPS25495.1 - 0.14 12.3 1.9 0.23 11.6 0.0 2.0 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal DUF4140 PF13600.6 EPS25495.1 - 1.6 9.2 0.0 1.6 9.2 0.0 2.2 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.15 EPS25495.1 - 3.8 7.4 10.0 9.1 6.1 0.3 2.2 2 0 0 2 2 2 0 Septum formation initiator APG6_N PF17675.1 EPS25495.1 - 8.4 6.9 14.5 6.3 7.3 0.2 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region HSP70 PF00012.20 EPS25496.1 - 2.1e-10 39.5 0.4 5.9e-09 34.7 0.2 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 EPS25496.1 - 0.056 12.3 0.1 0.4 9.5 0.0 2.0 2 0 0 2 2 2 0 MreB/Mbl protein N2227 PF07942.12 EPS25497.1 - 1.6e-88 296.4 0.0 2.3e-88 295.9 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein Methyltransf_11 PF08241.12 EPS25497.1 - 3.9e-05 24.2 0.0 0.00011 22.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPS25497.1 - 0.0053 17.5 0.0 0.021 15.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPS25497.1 - 0.014 16.1 0.0 0.04 14.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 EPS25497.1 - 0.024 14.4 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PAC4 PF16093.5 EPS25498.1 - 3.2e-26 91.3 0.5 4.1e-26 91.0 0.5 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 HMG_CoA_synt_C PF08540.10 EPS25499.1 - 1.6e-98 329.8 0.3 3.4e-98 328.7 0.3 1.5 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 EPS25499.1 - 1.3e-81 272.7 0.1 1.8e-81 272.2 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III_C PF08541.10 EPS25499.1 - 0.019 15.1 0.0 1.8 8.8 0.0 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Fungal_trans PF04082.18 EPS25503.1 - 6.2e-21 74.6 0.0 1.1e-20 73.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS25503.1 - 3.5e-06 27.0 12.2 8.8e-06 25.8 12.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF454 PF04304.13 EPS25503.1 - 0.19 11.7 0.3 0.4 10.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF454) LEAP-2 PF07359.11 EPS25503.1 - 0.58 10.0 4.1 2.4 8.0 4.1 2.1 1 0 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Peptidase_S10 PF00450.22 EPS25504.1 - 1.5e-91 308.0 3.6 1.8e-91 307.6 3.6 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase BRCT_2 PF16589.5 EPS25505.1 - 0.067 13.6 0.0 0.067 13.6 0.0 1.2 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain Rnk_N PF14760.6 EPS25505.1 - 0.096 13.2 0.0 0.15 12.6 0.0 1.3 1 0 0 1 1 1 0 Rnk N-terminus 4HBT_3 PF13622.6 EPS25506.1 - 1.8e-79 267.5 0.6 2.2e-79 267.2 0.6 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EPS25506.1 - 4.2e-26 91.4 0.0 2.8e-13 49.9 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase RNB PF00773.19 EPS25506.1 - 0.021 14.2 0.0 0.029 13.7 0.0 1.1 1 0 0 1 1 1 0 RNB domain DUF3445 PF11927.8 EPS25507.1 - 7.2e-72 241.7 0.0 9e-72 241.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) BTB_2 PF02214.22 EPS25507.1 - 0.074 13.4 1.4 2 8.8 0.0 3.3 3 1 1 4 4 4 0 BTB/POZ domain DUF3963 PF13124.6 EPS25507.1 - 0.18 11.8 0.1 1.4 9.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3963) MFS_1 PF07690.16 EPS25509.1 - 6.6e-33 114.1 35.6 6.6e-33 114.1 35.6 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS25509.1 - 1.8e-12 46.9 9.8 1.8e-12 46.9 9.8 1.8 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 EPS25509.1 - 4.1e-06 26.3 0.8 4.1e-06 26.3 0.8 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 EPS25509.1 - 3.3 5.9 17.3 0.4 8.9 2.1 2.8 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 EPS25510.1 - 2.2e-26 92.6 49.6 1.4e-20 73.5 30.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS25510.1 - 5.3e-18 65.1 22.3 7e-18 64.7 22.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Mito_carr PF00153.27 EPS25511.1 - 6.4e-46 154.2 7.5 7e-17 61.1 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein COesterase PF00135.28 EPS25512.1 - 2.3e-98 330.3 0.0 2.8e-98 330.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EPS25512.1 - 6.8e-10 39.2 1.0 4.5e-09 36.5 0.4 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold PAP_central PF04928.17 EPS25513.1 - 7.2e-109 362.5 0.0 1e-108 362.1 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 EPS25513.1 - 2.5e-59 199.7 0.0 3.6e-59 199.2 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 EPS25513.1 - 3.2e-11 43.4 0.0 6.8e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Abhydrolase_1 PF00561.20 EPS25515.1 - 6.1e-11 42.5 0.1 1.8e-10 40.9 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EPS25515.1 - 0.00031 20.3 0.0 0.0007 19.1 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EPS25515.1 - 0.0018 17.6 0.0 0.0033 16.7 0.0 1.4 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EPS25515.1 - 0.0034 18.0 0.0 0.0045 17.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 EPS25515.1 - 0.076 12.6 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DLH PF01738.18 EPS25515.1 - 0.15 11.6 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Flavin_Reduct PF01613.18 EPS25516.1 - 1.5e-19 70.6 0.0 2e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.12 EPS25516.1 - 0.086 12.6 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF447) RXT2_N PF08595.11 EPS25517.1 - 0.00019 21.5 1.4 0.00022 21.3 1.4 1.0 1 0 0 1 1 1 1 RXT2-like, N-terminal BSP_II PF05432.11 EPS25517.1 - 0.0023 17.7 8.6 0.0023 17.7 8.6 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) NOA36 PF06524.12 EPS25517.1 - 0.0038 16.6 3.3 0.0038 16.6 3.3 1.1 1 0 0 1 1 1 1 NOA36 protein DUF2052 PF09747.9 EPS25517.1 - 0.005 17.0 6.9 0.005 17.0 6.9 1.1 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) GOLD_2 PF13897.6 EPS25517.1 - 0.008 16.7 2.2 0.0088 16.5 2.2 1.1 1 0 0 1 1 1 1 Golgi-dynamics membrane-trafficking Tim54 PF11711.8 EPS25517.1 - 0.013 14.3 1.5 0.013 14.3 1.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TRAP_alpha PF03896.16 EPS25517.1 - 0.017 14.3 2.2 0.016 14.4 2.2 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RNA_pol_3_Rpc31 PF11705.8 EPS25517.1 - 0.024 14.9 7.8 0.023 15.0 7.8 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 FAM176 PF14851.6 EPS25517.1 - 0.029 14.0 5.5 0.037 13.7 5.5 1.1 1 0 0 1 1 1 0 FAM176 family Radial_spoke PF04712.12 EPS25517.1 - 0.03 13.3 11.5 0.032 13.2 11.5 1.0 1 0 0 1 1 1 0 Radial spokehead-like protein CPSF100_C PF13299.6 EPS25517.1 - 0.035 14.3 1.3 0.035 14.3 1.3 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal PTPRCAP PF15713.5 EPS25517.1 - 0.037 14.3 9.8 0.044 14.1 9.8 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated NPR3 PF03666.13 EPS25517.1 - 0.038 12.8 1.3 0.045 12.6 1.3 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF2098 PF09871.9 EPS25517.1 - 0.04 14.2 3.8 0.05 13.9 3.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) CDC45 PF02724.14 EPS25517.1 - 0.062 11.6 4.6 0.067 11.5 4.6 1.1 1 0 0 1 1 1 0 CDC45-like protein RNase_H2_suC PF08615.11 EPS25517.1 - 0.087 13.0 0.8 0.092 12.9 0.8 1.1 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Sporozoite_P67 PF05642.11 EPS25517.1 - 0.094 10.8 3.7 0.097 10.7 3.7 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RPN2_C PF18004.1 EPS25517.1 - 0.21 11.5 7.4 0.27 11.1 7.4 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF4746 PF15928.5 EPS25517.1 - 0.23 10.9 10.9 0.26 10.7 10.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) EIIBC-GUT_N PF03612.14 EPS25517.1 - 0.24 11.1 1.1 0.27 11.0 1.1 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus CbtA PF09490.10 EPS25517.1 - 0.36 10.6 2.0 0.41 10.4 2.0 1.1 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) DUF2457 PF10446.9 EPS25517.1 - 0.36 9.9 11.6 0.41 9.7 11.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CENP-B_dimeris PF09026.10 EPS25517.1 - 0.4 11.1 9.8 0.54 10.7 9.8 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pox_Ag35 PF03286.14 EPS25517.1 - 0.58 9.9 8.1 0.7 9.7 8.1 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PI3K_1B_p101 PF10486.9 EPS25517.1 - 0.75 7.5 4.6 0.82 7.4 4.6 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Paf1 PF03985.13 EPS25517.1 - 0.98 8.3 14.6 1.2 8.0 14.6 1.0 1 0 0 1 1 1 0 Paf1 Phage_Gp23 PF10669.9 EPS25517.1 - 1.1 9.6 9.4 1.3 9.4 9.4 1.1 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) DNA_pol_phi PF04931.13 EPS25517.1 - 1.1 7.2 13.5 1.3 7.0 13.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi MscS_TM PF12794.7 EPS25517.1 - 1.2 8.0 3.2 1.2 7.9 3.2 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Nop14 PF04147.12 EPS25517.1 - 1.4 7.0 12.8 1.7 6.7 12.8 1.0 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.12 EPS25517.1 - 2.4 7.5 12.1 3.2 7.1 12.1 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF1840 PF08895.11 EPS25517.1 - 7.2 7.0 10.4 14 6.1 10.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1840) Fungal_trans PF04082.18 EPS25518.1 - 1.1e-22 80.4 0.1 1.1e-20 73.8 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS25518.1 - 5.1e-07 29.7 8.2 8.5e-07 29.0 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2039 PF10217.9 EPS25518.1 - 1.2 9.5 6.2 3 8.2 6.2 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) Cu-oxidase_3 PF07732.15 EPS25520.1 - 3.5e-34 117.4 0.2 1.3e-33 115.5 0.1 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EPS25520.1 - 6.2e-29 100.5 1.4 8.4e-23 80.6 0.1 2.8 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 EPS25520.1 - 2.2e-16 60.4 0.0 9.4e-16 58.3 0.0 2.0 2 1 0 2 2 2 1 Multicopper oxidase Homeobox_KN PF05920.11 EPS25521.1 - 8.8e-16 57.5 1.3 2e-15 56.4 1.3 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 EPS25521.1 - 1.5e-05 24.7 0.3 4.8e-05 23.1 0.3 1.9 1 0 0 1 1 1 1 Homeodomain zf-C2H2_4 PF13894.6 EPS25521.1 - 0.0045 17.7 1.3 0.0045 17.7 1.3 5.3 5 0 0 5 5 5 1 C2H2-type zinc finger HTH_Tnp_Tc5 PF03221.16 EPS25521.1 - 0.041 13.9 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain HTH_36 PF13730.6 EPS25521.1 - 0.16 11.9 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain zf-C2H2 PF00096.26 EPS25521.1 - 1 9.9 19.5 0.41 11.2 1.2 4.3 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 EPS25521.1 - 1.9 9.1 7.0 1.7 9.3 0.2 2.8 2 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats tRNA-synt_1b PF00579.25 EPS25522.1 - 2.5e-54 184.6 0.0 3.3e-54 184.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) UQ_con PF00179.26 EPS25524.1 - 4.9e-11 42.4 0.0 7.8e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EPS25524.1 - 0.14 12.4 0.1 0.28 11.5 0.1 1.4 1 0 0 1 1 1 0 RWD domain 2OG-FeII_Oxy_2 PF13532.6 EPS25526.1 - 7.1e-37 127.5 0.5 1.1e-36 126.9 0.5 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.12 EPS25526.1 - 1.3e-05 25.2 3.8 1.3e-05 25.2 3.8 1.9 2 0 0 2 2 2 1 GRF zinc finger CUE PF02845.16 EPS25526.1 - 0.034 13.9 0.1 0.063 13.0 0.1 1.4 1 0 0 1 1 1 0 CUE domain WD40 PF00400.32 EPS25527.1 - 1.8e-17 63.4 15.9 0.002 18.9 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Ccdc124 PF06244.12 EPS25528.1 - 1.2e-28 100.3 20.3 1.2e-28 100.3 20.3 2.4 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 UB2H PF14814.6 EPS25528.1 - 0.058 13.4 0.2 0.11 12.6 0.2 1.5 1 0 0 1 1 1 0 Bifunctional transglycosylase second domain TMEM214 PF10151.9 EPS25528.1 - 5.6 5.3 12.3 7.1 4.9 12.3 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Peptidase_C13 PF01650.18 EPS25529.1 - 3.4e-41 141.4 0.1 5e-41 140.9 0.1 1.2 1 0 0 1 1 1 1 Peptidase C13 family CDRT4 PF15213.6 EPS25529.1 - 0.0025 18.4 0.1 0.0044 17.6 0.1 1.3 1 0 0 1 1 1 1 CMT1A duplicated region transcript 4 protein CDC45 PF02724.14 EPS25530.1 - 2.2e-245 815.9 0.0 1.3e-244 813.3 0.0 2.7 1 1 0 1 1 1 1 CDC45-like protein Cwf_Cwc_15 PF04889.12 EPS25530.1 - 0.0037 17.0 6.0 0.0037 17.0 6.0 2.5 2 1 1 3 3 3 1 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.10 EPS25530.1 - 0.79 9.0 32.0 0.14 11.5 12.4 2.1 2 0 0 2 2 2 0 BUD22 SPX PF03105.19 EPS25530.1 - 1.5 8.7 23.0 4.9 7.0 1.6 2.4 3 0 0 3 3 3 0 SPX domain FAM60A PF15396.6 EPS25530.1 - 1.5 8.8 11.0 0.051 13.6 1.1 2.1 2 0 0 2 2 2 0 Protein Family FAM60A SURF6 PF04935.12 EPS25530.1 - 3.4 7.4 23.9 0.68 9.7 16.3 2.3 2 0 0 2 2 2 0 Surfeit locus protein 6 PNISR PF15996.5 EPS25530.1 - 3.4 7.9 17.7 0.22 11.8 5.1 2.2 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR RNA_pol_3_Rpc31 PF11705.8 EPS25530.1 - 3.6 7.8 24.1 0.89 9.8 13.5 2.5 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 SBD_N PF07005.11 EPS25531.1 - 1.5e-60 204.8 0.1 2.9e-60 203.9 0.0 1.5 2 0 0 2 2 2 1 Sugar-binding N-terminal domain NBD_C PF17042.5 EPS25531.1 - 3.2e-43 148.2 0.7 2.6e-42 145.2 0.8 2.1 2 0 0 2 2 2 1 Nucleotide-binding C-terminal domain Cupin_8 PF13621.6 EPS25532.1 - 9.3e-30 104.2 0.0 3e-29 102.5 0.0 1.8 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EPS25532.1 - 3.9e-06 26.6 0.1 0.00039 20.0 0.0 2.2 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.22 EPS25532.1 - 0.008 16.6 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 EPS25532.1 - 0.012 15.4 0.0 0.042 13.5 0.0 1.9 1 0 0 1 1 1 0 Cupin domain GTP1_OBG PF01018.22 EPS25533.1 - 2.1e-40 137.8 5.6 1.2e-29 103.0 6.4 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 EPS25533.1 - 6.8e-22 77.7 0.0 1.3e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EPS25533.1 - 3.8e-08 33.0 0.0 8.3e-08 31.9 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.27 EPS25533.1 - 0.011 16.3 1.3 0.029 14.9 0.0 2.1 2 0 0 2 2 2 0 ABC transporter GTP_EFTU PF00009.27 EPS25533.1 - 0.012 15.2 0.0 2 7.9 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MeaB PF03308.16 EPS25533.1 - 0.013 14.5 0.1 1.4 7.8 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Ploopntkinase3 PF18751.1 EPS25533.1 - 0.033 14.1 0.0 0.06 13.3 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 MFS_1 PF07690.16 EPS25536.1 - 1.5e-37 129.3 10.5 7.2e-29 100.8 0.2 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS25536.1 - 3.3e-10 39.4 2.5 6.5e-10 38.4 2.5 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.13 EPS25536.1 - 2.2 6.6 9.4 0.71 8.2 3.2 2.4 2 1 0 2 2 2 0 Transmembrane secretion effector Fungal_trans PF04082.18 EPS25537.1 - 7.8e-28 97.2 0.0 1.5e-27 96.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS25537.1 - 1e-08 35.1 11.3 1.6e-08 34.5 11.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DnaJ PF00226.31 EPS25538.1 - 7.3e-21 74.1 1.3 7.3e-21 74.1 1.3 1.9 2 0 0 2 2 2 1 DnaJ domain Adenylsucc_synt PF00709.21 EPS25539.1 - 4.9e-166 552.8 0.0 5.5e-166 552.6 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase KHA PF11834.8 EPS25539.1 - 0.1 12.7 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 KHA, dimerisation domain of potassium ion channel DEAD PF00270.29 EPS25540.1 - 1.5e-43 148.6 0.1 2.6e-43 147.8 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPS25540.1 - 2.8e-20 72.7 0.1 9.7e-20 71.0 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPS25540.1 - 1.1e-05 25.5 0.0 2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 EPS25540.1 - 0.096 12.0 0.2 0.24 10.7 0.1 1.7 2 0 0 2 2 2 0 SecA DEAD-like domain ERCC3_RAD25_C PF16203.5 EPS25540.1 - 0.099 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase YcgL PF05166.13 EPS25540.1 - 0.18 12.2 0.0 0.5 10.7 0.0 1.8 1 0 0 1 1 1 0 YcgL domain Pyr_redox_2 PF07992.14 EPS25541.1 - 8.1e-40 136.9 0.0 1e-39 136.5 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPS25541.1 - 4.8e-15 55.9 0.9 1.6e-10 41.4 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EPS25541.1 - 2e-08 34.4 3.6 0.0015 18.6 0.0 4.2 3 1 1 4 4 4 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EPS25541.1 - 1.2e-07 31.1 4.5 4.9e-05 22.6 0.0 3.3 2 1 0 3 3 3 2 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EPS25541.1 - 6.5e-06 25.6 0.2 0.0014 17.9 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EPS25541.1 - 6.8e-06 25.5 2.4 0.00032 20.0 0.1 2.5 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 EPS25541.1 - 3.1e-05 23.7 5.1 0.0016 18.1 0.1 3.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 EPS25541.1 - 6.9e-05 22.1 0.5 0.16 11.1 0.1 2.4 1 1 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 EPS25541.1 - 0.00055 18.9 6.0 0.84 8.4 0.1 3.1 2 1 0 3 3 3 2 Tryptophan halogenase NAD_binding_8 PF13450.6 EPS25541.1 - 0.0013 18.9 0.2 0.0065 16.7 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 EPS25541.1 - 0.0015 18.8 0.2 0.82 9.9 0.0 2.7 2 0 0 2 2 2 1 TrkA-N domain NAD_binding_7 PF13241.6 EPS25541.1 - 0.0015 18.9 0.1 2.2 8.7 0.0 2.5 2 0 0 2 2 2 2 Putative NAD(P)-binding ApbA PF02558.16 EPS25541.1 - 0.015 15.0 0.4 0.86 9.2 0.0 2.6 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 EPS25541.1 - 0.021 15.1 0.3 1.7 8.9 0.0 2.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain FAD_binding_2 PF00890.24 EPS25541.1 - 0.036 13.2 0.3 0.12 11.4 0.0 2.0 3 0 0 3 3 3 0 FAD binding domain FAD_binding_3 PF01494.19 EPS25541.1 - 0.044 13.0 2.6 0.19 10.9 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain Shikimate_DH PF01488.20 EPS25541.1 - 0.06 13.4 0.2 2.5 8.1 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase KR PF08659.10 EPS25541.1 - 0.068 13.1 0.2 0.2 11.6 0.1 1.9 2 0 0 2 2 1 0 KR domain HI0933_like PF03486.14 EPS25541.1 - 0.094 11.4 2.8 0.74 8.4 0.0 2.9 3 1 1 4 4 4 0 HI0933-like protein GIDA PF01134.22 EPS25541.1 - 0.11 11.5 8.4 5.8 5.9 0.0 4.0 2 1 1 4 4 4 0 Glucose inhibited division protein A ThiF PF00899.21 EPS25541.1 - 0.3 10.4 1.6 2.3 7.5 0.1 2.2 2 0 0 2 2 2 0 ThiF family ADH_zinc_N PF00107.26 EPS25542.1 - 4.5e-24 84.9 0.0 7.1e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EPS25542.1 - 1.9e-21 76.0 0.0 3.2e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 EPS25542.1 - 1.8e-08 35.5 0.0 3.5e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CybS PF05328.12 EPS25543.1 - 1.2e-51 173.9 0.0 1.5e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Maf PF02545.14 EPS25544.1 - 5.3e-48 163.0 0.1 6.3e-48 162.8 0.1 1.1 1 0 0 1 1 1 1 Maf-like protein HLH PF00010.26 EPS25545.1 - 3.6e-09 36.4 0.0 5.4e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Umbravirus_LDM PF04817.12 EPS25545.1 - 0.0024 17.3 0.1 0.0027 17.1 0.1 1.0 1 0 0 1 1 1 1 Umbravirus long distance movement (LDM) family GFA PF04828.14 EPS25546.1 - 0.035 14.5 0.0 0.066 13.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme Abhydrolase_1 PF00561.20 EPS25548.1 - 1e-10 41.7 0.1 1.9e-10 40.8 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPS25548.1 - 1.1e-07 32.7 4.3 1.4e-07 32.3 4.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPS25548.1 - 5.2e-06 25.9 0.1 1.3e-05 24.6 0.0 1.6 1 1 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 EPS25548.1 - 0.0014 18.3 0.0 0.0027 17.4 0.0 1.5 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Ndr PF03096.14 EPS25548.1 - 0.028 13.1 0.1 0.044 12.5 0.1 1.2 1 0 0 1 1 1 0 Ndr family Fungal_trans PF04082.18 EPS25549.1 - 6.7e-22 77.8 0.1 1.1e-21 77.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS25549.1 - 3.4e-05 23.9 12.3 6.2e-05 23.0 12.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EPS25550.1 - 4.7e-44 150.8 39.4 9.2e-44 149.8 32.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS25550.1 - 7.4e-13 48.2 8.3 7.4e-13 48.2 8.3 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter NADHdh_A3 PF14987.6 EPS25550.1 - 1 9.7 7.2 0.37 11.1 0.3 2.7 2 0 0 2 2 2 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 SLATT_3 PF18184.1 EPS25550.1 - 5.5 7.1 5.4 0.79 9.9 0.5 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 3 SCAMP PF04144.13 EPS25551.1 - 9.7 6.5 18.8 2 8.7 3.0 2.5 2 1 1 3 3 3 0 SCAMP family Fungal_trans_2 PF11951.8 EPS25552.1 - 2.6e-13 49.6 4.8 4.2e-12 45.6 4.8 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS25552.1 - 2.2e-07 30.9 11.0 2.2e-07 30.9 11.0 2.6 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SLATT_1 PF18181.1 EPS25552.1 - 0.14 12.1 0.5 0.37 10.7 0.0 1.8 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 VWA_2 PF13519.6 EPS25553.1 - 0.0056 17.3 0.0 0.012 16.3 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 EPS25553.1 - 0.0058 16.9 0.0 0.013 15.8 0.0 1.6 1 1 0 1 1 1 1 von Willebrand factor type A domain ANAPC4 PF12896.7 EPS25555.1 - 7.5e-68 228.0 1.0 1.1e-67 227.6 1.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 EPS25555.1 - 9.5e-34 115.6 0.0 3.2e-32 110.7 0.0 2.8 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain HpaP PF09483.10 EPS25555.1 - 0.014 15.6 0.3 0.031 14.5 0.3 1.5 1 0 0 1 1 1 0 Type III secretion protein (HpaP) WD40 PF00400.32 EPS25555.1 - 0.25 12.3 3.2 0.7 10.9 0.0 3.5 5 0 0 5 5 5 0 WD domain, G-beta repeat HEAT_EZ PF13513.6 EPS25556.1 - 4.7e-13 49.3 2.1 3.3e-09 37.0 0.2 6.4 6 2 2 8 8 8 2 HEAT-like repeat HEAT PF02985.22 EPS25556.1 - 5.4e-13 48.0 14.2 0.00021 21.3 0.2 8.6 8 1 0 8 8 7 3 HEAT repeat IBN_N PF03810.19 EPS25556.1 - 1e-09 38.2 2.6 6.3e-08 32.4 0.3 4.0 4 0 0 4 4 4 1 Importin-beta N-terminal domain CLASP_N PF12348.8 EPS25556.1 - 4.6e-06 26.4 0.1 0.22 11.1 0.0 4.4 3 2 1 5 5 5 2 CLASP N terminal HEAT_2 PF13646.6 EPS25556.1 - 1.2e-05 25.5 12.9 0.022 15.2 0.5 6.1 3 2 4 7 7 7 4 HEAT repeats DUF3385 PF11865.8 EPS25556.1 - 0.00023 21.1 2.8 0.41 10.5 0.0 3.7 3 1 1 4 4 4 2 Domain of unknown function (DUF3385) Dopey_N PF04118.14 EPS25556.1 - 0.00098 18.3 0.3 0.14 11.3 0.0 2.8 3 0 0 3 3 3 1 Dopey, N-terminal DRIM PF07539.12 EPS25556.1 - 0.0059 15.0 4.3 5.2 5.2 0.0 4.3 3 1 0 4 4 4 1 Down-regulated in metastasis HEAT_PBS PF03130.16 EPS25556.1 - 0.032 14.9 1.2 1.1e+02 3.9 0.0 5.3 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Orbi_NS3 PF01616.16 EPS25556.1 - 0.043 13.5 0.1 0.1 12.3 0.1 1.6 1 0 0 1 1 1 0 Orbivirus NS3 Cse1 PF08506.10 EPS25556.1 - 0.044 12.6 0.2 1.5 7.6 0.1 3.2 3 1 1 4 4 4 0 Cse1 PNPase PF03726.14 EPS25556.1 - 0.15 12.6 1.0 0.98 10.0 0.0 2.8 3 0 0 3 3 3 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain Arm PF00514.23 EPS25556.1 - 0.36 10.9 4.3 11 6.3 0.3 4.2 4 0 0 4 4 3 0 Armadillo/beta-catenin-like repeat Ribosomal_S8 PF00410.19 EPS25557.1 - 2.7e-21 75.8 0.0 3.9e-21 75.3 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S8 His_Phos_1 PF00300.22 EPS25558.1 - 1.4e-12 47.7 0.0 8.5e-07 28.9 0.0 3.0 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) ubiquitin PF00240.23 EPS25559.1 - 8e-06 25.5 1.3 1e-05 25.1 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin family DUF2407 PF10302.9 EPS25559.1 - 0.0053 17.3 2.9 0.0081 16.7 0.0 2.4 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain CCDC53 PF10152.9 EPS25559.1 - 0.37 11.2 10.0 1.2 9.6 10.0 1.8 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF4834 PF16118.5 EPS25559.1 - 0.87 10.6 3.6 2.4 9.2 3.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) PhnG PF06754.12 EPS25559.1 - 1.5 8.7 8.8 7 6.6 8.1 2.3 2 0 0 2 2 2 0 Phosphonate metabolism protein PhnG Spore_coat_CotO PF14153.6 EPS25559.1 - 2.9 7.8 13.4 5.2 7.0 13.4 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Roughex PF06020.11 EPS25559.1 - 5 6.1 8.5 9.8 5.2 8.5 1.4 1 0 0 1 1 1 0 Drosophila roughex protein PS_Dcarbxylase PF02666.15 EPS25560.1 - 3.4e-78 261.8 0.0 5.8e-77 257.8 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase FAD_binding_3 PF01494.19 EPS25561.1 - 2.6e-10 40.1 0.1 8.6e-10 38.4 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EPS25561.1 - 5.5e-06 25.8 0.0 0.0051 16.1 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EPS25561.1 - 1.9e-05 24.5 0.2 0.00044 19.9 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EPS25561.1 - 0.00022 21.7 0.0 0.0027 18.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPS25561.1 - 0.00023 21.3 0.0 0.00059 20.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EPS25561.1 - 0.0016 17.7 0.0 0.15 11.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase CoA_transf_3 PF02515.17 EPS25561.1 - 0.015 14.4 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 CoA-transferase family III NAD_binding_7 PF13241.6 EPS25561.1 - 0.041 14.3 0.0 0.085 13.3 0.0 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.16 EPS25561.1 - 0.092 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.22 EPS25561.1 - 0.1 11.6 0.5 0.44 9.6 0.2 1.9 1 1 1 2 2 2 0 Glucose inhibited division protein A Fungal_trans PF04082.18 EPS25562.1 - 4.2e-10 39.1 0.0 7.1e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS25562.1 - 6.5e-09 35.8 9.4 1.2e-08 34.9 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mem_trans PF03547.18 EPS25563.1 - 1.7e-55 188.0 0.1 6.4e-55 186.1 0.1 1.7 1 1 0 1 1 1 1 Membrane transport protein Cu-oxidase_3 PF07732.15 EPS25564.1 - 9.3e-37 125.7 0.2 1.5e-34 118.6 0.0 3.1 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EPS25564.1 - 7.6e-30 103.4 6.7 5e-29 100.8 1.6 4.1 4 1 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.22 EPS25564.1 - 3e-16 60.0 0.0 3e-15 56.7 0.0 2.2 2 0 0 2 2 2 1 Multicopper oxidase HAUS5 PF14817.6 EPS25564.1 - 0.27 9.9 0.0 0.39 9.4 0.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Phosphoesterase PF04185.14 EPS25566.1 - 6.9e-72 242.6 2.8 9e-72 242.2 2.8 1.1 1 0 0 1 1 1 1 Phosphoesterase family Inhibitor_I66 PF16850.5 EPS25566.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase inhibitor I66 ApbA_C PF08546.11 EPS25567.1 - 1.1e-33 116.1 0.0 1.5e-33 115.6 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EPS25567.1 - 3.6e-28 98.1 0.0 8e-28 97.0 0.0 1.5 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Ribonuc_L-PSP PF01042.21 EPS25568.1 - 3e-37 127.3 0.0 3.4e-37 127.1 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP GPI-anchored PF10342.9 EPS25569.1 - 0.00071 20.3 0.1 0.0012 19.5 0.1 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF5543 PF17697.1 EPS25570.1 - 0.021 15.1 0.1 0.032 14.5 0.1 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5543) Choline_kinase PF01633.20 EPS25571.1 - 2.1e-59 200.7 0.0 3.1e-59 200.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 EPS25571.1 - 1.4e-14 53.4 0.0 2.9e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.23 EPS25571.1 - 5.5e-06 26.5 0.3 3.3e-05 23.9 0.1 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Peptidase_C12 PF01088.21 EPS25572.1 - 5.1e-70 235.5 0.0 6.4e-70 235.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 EPS25572.1 - 2.9e-10 39.9 0.0 2.9e-10 39.9 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolases PFU PF09070.11 EPS25572.1 - 0.012 15.8 0.1 0.026 14.8 0.1 1.5 1 0 0 1 1 1 0 PFU (PLAA family ubiquitin binding) Cellulase PF00150.18 EPS25573.1 - 4e-56 190.5 0.7 5.3e-56 190.1 0.7 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 EPS25573.1 - 5e-12 45.6 17.2 5e-12 45.6 17.2 2.4 3 0 0 3 3 3 1 Fungal cellulose binding domain Ribosomal_S2 PF00318.20 EPS25573.1 - 0.011 15.0 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S2 Toxin_7 PF05980.12 EPS25573.1 - 0.024 14.9 1.3 0.074 13.3 1.3 1.8 1 0 0 1 1 1 0 Toxin 7 PAN_3 PF08277.12 EPS25574.1 - 2e-06 27.5 31.0 0.011 15.6 5.0 4.5 4 0 0 4 4 4 3 PAN-like domain PAN_4 PF14295.6 EPS25574.1 - 0.029 14.3 2.4 0.029 14.3 2.4 5.7 6 0 0 6 6 6 0 PAN domain CAP_N PF01213.19 EPS25574.1 - 2 7.9 4.2 3.2 7.2 4.2 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal VWA_2 PF13519.6 EPS25575.1 - 0.013 16.1 0.1 0.037 14.7 0.1 1.8 1 0 0 1 1 1 0 von Willebrand factor type A domain Neural_ProG_Cyt PF06567.11 EPS25575.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 Neural chondroitin sulphate proteoglycan cytoplasmic domain Zn_clus PF00172.18 EPS25576.1 - 6.7e-07 29.3 14.6 1.4e-06 28.3 14.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EPS25576.1 - 1.3e-05 24.2 1.9 1.3e-05 24.2 1.9 1.8 2 1 0 2 2 2 1 Fungal specific transcription factor domain CVNH PF08881.10 EPS25579.1 - 1e-07 32.6 0.0 2e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 CVNH domain CVNH PF08881.10 EPS25580.1 - 1.2e-09 38.7 0.0 1.4e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 CVNH domain HEAT_EZ PF13513.6 EPS25581.1 - 1.4e-32 111.7 9.8 4.6e-15 55.7 0.1 9.3 8 2 2 10 10 10 4 HEAT-like repeat HEAT PF02985.22 EPS25581.1 - 6.4e-20 69.5 15.2 0.0002 21.4 0.0 10.0 11 0 0 11 11 10 5 HEAT repeat HEAT_2 PF13646.6 EPS25581.1 - 4e-19 68.8 0.3 0.026 14.9 0.0 8.6 6 3 3 10 10 10 3 HEAT repeats Cnd1 PF12717.7 EPS25581.1 - 4.6e-11 43.0 2.6 6.6e-05 23.0 0.0 5.5 5 1 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EPS25581.1 - 1.6e-08 33.6 3.3 0.0003 19.5 0.2 4.6 3 2 1 4 4 4 2 Adaptin N terminal region CLASP_N PF12348.8 EPS25581.1 - 1.7e-08 34.3 0.1 4.5 6.8 0.0 7.1 3 1 3 7 7 7 2 CLASP N terminal Vac14_Fab1_bd PF12755.7 EPS25581.1 - 6e-08 33.2 0.1 0.27 11.8 0.0 5.9 4 2 2 6 6 6 2 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 EPS25581.1 - 2.8e-07 30.0 3.1 0.077 12.1 0.0 5.2 3 1 3 6 6 6 3 RNAPII transcription regulator C-terminal RIX1 PF08167.12 EPS25581.1 - 0.0039 17.0 0.0 11 5.8 0.0 4.5 4 1 1 5 5 5 1 rRNA processing/ribosome biogenesis DUF3437 PF11919.8 EPS25581.1 - 0.032 14.1 0.0 1.4 8.9 0.0 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) IBN_N PF03810.19 EPS25581.1 - 0.04 13.8 0.5 4.5 7.3 0.0 3.8 4 1 0 4 4 3 0 Importin-beta N-terminal domain Sec7_N PF12783.7 EPS25581.1 - 0.041 13.8 1.1 0.92 9.4 0.0 3.0 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Arm PF00514.23 EPS25581.1 - 0.046 13.8 4.9 4.6 7.4 0.0 5.4 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat TAFH PF07531.14 EPS25581.1 - 0.076 13.1 4.0 23 5.2 0.0 4.7 5 0 0 5 5 4 0 NHR1 homology to TAF HEAT_PBS PF03130.16 EPS25581.1 - 0.16 12.7 5.0 19 6.3 0.0 5.1 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat Syja_N PF02383.18 EPS25582.1 - 8.2e-94 314.5 0.0 1.2e-93 314.0 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.8 EPS25582.1 - 9e-38 128.5 0.0 1.9e-37 127.5 0.0 1.6 1 0 0 1 1 1 1 Inositol phosphatase Mg_trans_NIPA PF05653.14 EPS25583.1 - 1.2e-98 329.9 14.3 1.4e-98 329.7 14.3 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EPS25583.1 - 1.2e-05 25.5 6.4 1.2e-05 25.5 6.4 2.5 2 0 0 2 2 2 2 EamA-like transporter family DUF2420 PF10336.9 EPS25585.1 - 2.2e-16 59.8 0.2 4.5e-16 58.8 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Adap_comp_sub PF00928.21 EPS25586.1 - 1.5e-18 67.1 0.0 2.4e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EPS25586.1 - 3.8e-07 30.1 0.2 6.2e-07 29.4 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 EPS25586.1 - 1.5e-06 27.9 0.1 9.9e-06 25.2 0.1 2.0 1 1 0 1 1 1 1 Muniscin C-terminal mu homology domain RPM2 PF08579.11 EPS25586.1 - 0.00032 21.1 0.4 0.00068 20.0 0.4 1.5 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) EspF PF04806.12 EPS25586.1 - 1.2 9.6 4.2 4.1 7.9 3.7 2.1 2 0 0 2 2 2 0 EspF protein repeat Fungal_trans PF04082.18 EPS25587.1 - 3.2e-16 59.2 0.2 5.5e-16 58.4 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS25587.1 - 4.4e-05 23.5 16.2 9.5e-05 22.4 16.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OMPdecase PF00215.24 EPS25589.1 - 3.4e-06 26.8 0.0 1.5e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Vps62 PF06101.11 EPS25589.1 - 0.048 12.0 0.0 0.062 11.6 0.0 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 62 SufE PF02657.15 EPS25590.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Fe-S metabolism associated domain Cyt-b5 PF00173.28 EPS25591.1 - 1e-19 70.4 0.1 1e-19 70.4 0.1 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 EPS25591.1 - 3.5e-13 50.1 17.6 5.8e-13 49.3 16.4 1.8 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily UPF0730 PF15827.5 EPS25591.1 - 0.044 13.5 2.9 0.24 11.1 1.4 2.4 2 0 0 2 2 2 0 UPF0730 unknown protein family Anth_synt_I_N PF04715.13 EPS25591.1 - 0.066 13.4 0.2 0.14 12.4 0.2 1.5 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region RRM_1 PF00076.22 EPS25592.1 - 1e-44 150.2 0.3 1.5e-21 76.0 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 EPS25592.1 - 2.6e-24 86.1 0.1 1.1e-23 84.2 0.1 2.1 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 EPS25592.1 - 3.9e-06 26.6 0.0 0.0034 17.2 0.0 3.1 3 0 0 3 3 3 1 Occluded RNA-recognition motif Limkain-b1 PF11608.8 EPS25592.1 - 0.004 17.2 0.1 0.49 10.5 0.0 3.0 2 1 0 2 2 2 1 Limkain b1 PHM7_cyt PF14703.6 EPS25592.1 - 0.0072 16.6 0.1 1.2 9.4 0.1 2.8 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RRM_3 PF08777.11 EPS25592.1 - 0.012 15.6 0.0 0.068 13.2 0.0 2.1 2 0 0 2 2 2 0 RNA binding motif RRM_5 PF13893.6 EPS25592.1 - 0.016 14.8 0.0 0.04 13.5 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EPS25592.1 - 0.026 14.7 0.0 0.66 10.1 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif PP2C PF00481.21 EPS25593.1 - 7.1e-35 120.9 0.0 2.3e-28 99.5 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 EPS25593.1 - 0.007 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C CDP-OH_P_transf PF01066.21 EPS25595.1 - 3.1e-13 50.3 0.7 3.1e-13 50.3 0.7 2.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Zn_clus PF00172.18 EPS25597.1 - 2.9e-08 33.7 13.9 5.6e-08 32.8 13.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DnaJ PF00226.31 EPS25598.1 - 1.4e-16 60.3 0.4 4.3e-16 58.8 0.4 1.9 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.16 EPS25598.1 - 1.7e-12 47.0 0.0 1.1e-11 44.5 0.0 2.0 1 1 0 1 1 1 1 Sec63 Brl domain Peptidase_M24 PF00557.24 EPS25600.1 - 2.4e-58 197.3 0.0 3.7e-58 196.7 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EPS25600.1 - 6.5e-21 74.3 0.0 1.2e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain SPRY PF00622.28 EPS25601.1 - 5e-20 71.8 0.1 1.2e-19 70.6 0.0 1.7 2 0 0 2 2 2 1 SPRY domain PDEase_II PF02112.15 EPS25602.1 - 8.3e-48 163.2 0.0 2.4e-24 86.1 0.0 3.3 4 0 0 4 4 4 3 cAMP phosphodiesterases class-II Lactamase_B PF00753.27 EPS25602.1 - 0.0017 18.4 0.2 0.0039 17.2 0.2 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EPS25602.1 - 0.0052 16.3 0.0 0.0094 15.5 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Acyl-CoA_dh_1 PF00441.24 EPS25603.1 - 1.2e-38 132.7 8.5 2.1e-38 131.9 8.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EPS25603.1 - 1.7e-26 93.1 3.3 2.8e-26 92.4 0.1 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EPS25603.1 - 6.4e-25 87.2 0.0 1.5e-24 86.0 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EPS25603.1 - 1.5e-16 60.9 3.4 2.7e-16 60.1 3.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 EPS25603.1 - 0.013 15.2 0.0 0.035 13.8 0.0 1.7 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal bZIP_1 PF00170.21 EPS25604.1 - 1.8e-07 31.1 8.3 1.3e-06 28.4 5.8 2.3 1 1 1 2 2 2 1 bZIP transcription factor Mito_fiss_reg PF05308.11 EPS25604.1 - 0.00011 22.4 13.5 0.00011 22.4 13.5 2.6 2 1 0 2 2 2 1 Mitochondrial fission regulator HALZ PF02183.18 EPS25604.1 - 0.0003 20.9 1.5 0.00052 20.2 1.5 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper NPV_P10 PF05531.12 EPS25604.1 - 0.0014 19.1 1.1 0.0026 18.2 1.1 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein bZIP_2 PF07716.15 EPS25604.1 - 0.0018 18.3 13.5 0.022 14.9 7.8 2.3 1 1 1 2 2 2 2 Basic region leucine zipper YabA PF06156.13 EPS25604.1 - 0.013 16.2 0.5 0.025 15.2 0.5 1.5 1 0 0 1 1 1 0 Initiation control protein YabA Med9 PF07544.13 EPS25604.1 - 0.015 15.4 7.2 0.031 14.4 7.2 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 FlxA PF14282.6 EPS25604.1 - 0.023 14.7 9.6 0.023 14.7 9.6 1.9 2 0 0 2 2 2 0 FlxA-like protein Phage_GP20 PF06810.11 EPS25604.1 - 0.031 14.1 3.0 0.044 13.6 3.0 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 Fungal_TACC PF12709.7 EPS25604.1 - 0.038 14.4 1.2 0.068 13.6 0.7 1.6 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins DivIC PF04977.15 EPS25604.1 - 0.039 13.7 1.5 0.039 13.7 1.5 2.3 1 1 1 2 2 2 0 Septum formation initiator FNIP_M PF14637.6 EPS25604.1 - 0.062 13.3 0.2 0.087 12.8 0.2 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein middle domain Cnn_1N PF07989.11 EPS25604.1 - 0.075 13.2 5.3 0.13 12.4 3.2 2.1 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 GAS PF13851.6 EPS25604.1 - 0.11 11.9 7.4 0.15 11.4 7.4 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding BLOC1_2 PF10046.9 EPS25604.1 - 0.15 12.4 2.6 0.24 11.7 2.6 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlaC_arch PF05377.11 EPS25604.1 - 0.25 11.8 0.9 0.78 10.2 0.9 1.8 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF1192 PF06698.11 EPS25604.1 - 0.35 11.0 3.3 0.81 9.8 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) Fzo_mitofusin PF04799.13 EPS25604.1 - 0.53 9.8 4.2 0.81 9.2 4.2 1.2 1 0 0 1 1 1 0 fzo-like conserved region DUF3450 PF11932.8 EPS25604.1 - 0.54 9.5 9.4 0.86 8.9 9.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF484 PF04340.12 EPS25604.1 - 0.98 9.1 5.8 0.85 9.3 4.5 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF484 ABC_tran_CTD PF16326.5 EPS25604.1 - 1.1 9.5 5.4 2 8.7 5.4 1.4 1 0 0 1 1 1 0 ABC transporter C-terminal domain Csm1_N PF18504.1 EPS25604.1 - 1.3 9.4 6.0 11 6.4 2.4 2.3 1 1 1 2 2 2 0 Csm1 N-terminal domain ATG16 PF08614.11 EPS25604.1 - 4.8 7.4 15.5 0.16 12.1 9.6 1.5 2 0 0 2 2 1 0 Autophagy protein 16 (ATG16) GWT1 PF06423.12 EPS25605.1 - 1.6e-40 138.6 1.8 4.4e-39 134.0 2.4 2.5 2 1 0 2 2 2 1 GWT1 DUF4818 PF16089.5 EPS25605.1 - 0.0051 17.3 0.2 0.022 15.2 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4818) Amidase PF01425.21 EPS25606.1 - 4e-86 289.8 0.0 2.5e-85 287.1 0.0 1.9 1 1 0 1 1 1 1 Amidase ANAPC10 PF03256.16 EPS25607.1 - 3.6e-46 157.2 0.0 5.5e-46 156.6 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) PTPRCAP PF15713.5 EPS25607.1 - 0.059 13.7 16.6 0.019 15.2 13.6 1.8 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated Radial_spoke PF04712.12 EPS25607.1 - 0.13 11.2 14.9 0.3 10.0 14.9 1.6 1 0 0 1 1 1 0 Radial spokehead-like protein Mpp10 PF04006.12 EPS25607.1 - 0.29 9.5 20.7 0.44 8.9 20.7 1.2 1 0 0 1 1 1 0 Mpp10 protein NPR3 PF03666.13 EPS25607.1 - 0.37 9.5 0.8 0.62 8.8 0.8 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 AIF_C PF14721.6 EPS25607.1 - 0.46 10.8 1.6 0.84 10.0 1.6 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Tim54 PF11711.8 EPS25607.1 - 0.64 8.7 4.6 1.1 7.9 4.6 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CDC45 PF02724.14 EPS25607.1 - 0.68 8.2 15.4 1 7.6 15.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.22 EPS25607.1 - 1.2 8.3 2.5 1.6 7.9 2.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter BUD22 PF09073.10 EPS25607.1 - 2.8 7.2 16.5 1.5 8.1 14.3 1.5 2 0 0 2 2 2 0 BUD22 PI3K_1B_p101 PF10486.9 EPS25607.1 - 3.3 5.4 5.3 4.7 4.9 5.3 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DARPP-32 PF05395.12 EPS25607.1 - 7.1 6.8 19.8 18 5.5 19.8 1.7 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 Iso_dh PF00180.20 EPS25608.1 - 7.4e-130 433.1 0.0 8.4e-130 433.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase AAA_lid_3 PF17862.1 EPS25608.1 - 0.094 12.5 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA+ lid domain ALO PF04030.14 EPS25609.1 - 8.2e-89 297.9 0.2 1.2e-88 297.3 0.2 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 EPS25609.1 - 5.9e-34 116.8 0.1 8.8e-34 116.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DUF4045 PF13254.6 EPS25610.1 - 7.3e-138 460.7 41.6 7.3e-138 460.7 41.6 5.9 3 2 1 4 4 4 1 Domain of unknown function (DUF4045) Gelsolin PF00626.22 EPS25610.1 - 5.5e-10 39.0 0.0 0.071 13.0 0.0 3.6 3 0 0 3 3 3 3 Gelsolin repeat FliT PF05400.13 EPS25610.1 - 4.9 8.0 6.1 2.1 9.2 1.4 2.7 3 0 0 3 3 3 0 Flagellar protein FliT Arf PF00025.21 EPS25611.1 - 1.8e-64 216.4 1.7 2e-64 216.2 1.7 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EPS25611.1 - 3.6e-13 49.4 0.0 4.2e-13 49.2 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EPS25611.1 - 5.4e-12 45.5 3.6 4.6e-07 29.3 0.9 2.6 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EPS25611.1 - 5.9e-12 45.9 0.1 8.2e-12 45.4 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 EPS25611.1 - 8.3e-11 41.7 0.0 1e-10 41.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EPS25611.1 - 4.6e-08 32.7 0.0 5.5e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EPS25611.1 - 5.2e-08 33.0 0.0 7.2e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EPS25611.1 - 3.7e-06 26.6 0.0 0.0001 21.9 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain HCV_NS1 PF01560.17 EPS25611.1 - 0.0017 17.1 0.0 0.002 16.9 0.0 1.1 1 0 0 1 1 1 1 Hepatitis C virus non-structural protein E2/NS1 FeoB_N PF02421.18 EPS25611.1 - 0.0059 16.1 0.4 0.018 14.6 0.4 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B NACHT PF05729.12 EPS25611.1 - 0.068 13.1 0.2 1.5 8.7 0.0 2.1 2 0 0 2 2 2 0 NACHT domain 6PF2K PF01591.18 EPS25611.1 - 0.075 12.3 0.2 0.19 11.0 0.1 1.6 1 1 0 2 2 2 0 6-phosphofructo-2-kinase DEAD PF00270.29 EPS25612.1 - 2.4e-47 160.9 0.0 5e-47 159.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPS25612.1 - 1.4e-29 102.6 0.1 2.6e-28 98.6 0.1 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain UTP25 PF06862.12 EPS25612.1 - 0.00062 18.7 0.5 0.0028 16.5 0.0 2.3 2 1 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DHHW PF14286.6 EPS25612.1 - 5.6 6.2 0.0 5.6 6.2 0.0 3.9 3 1 1 4 4 4 0 DHHW protein Fungal_trans PF04082.18 EPS25614.1 - 3.3e-23 82.1 0.0 3.3e-23 82.1 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS25614.1 - 8.2e-11 41.8 6.9 1.4e-10 41.1 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EPL1 PF10513.9 EPS25614.1 - 1.1 9.6 6.9 2 8.8 6.9 1.4 1 0 0 1 1 1 0 Enhancer of polycomb-like TFIIA PF03153.13 EPS25614.1 - 1.6 8.7 18.3 2.8 7.8 18.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 EPS25614.1 - 3.5 6.3 9.5 6.4 5.4 9.5 1.3 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 EPS25614.1 - 3.8 5.7 16.5 5.3 5.2 16.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Opy2 PF09463.10 EPS25614.1 - 4.9 7.6 6.8 1 9.7 2.0 2.1 2 0 0 2 2 2 0 Opy2 protein Ferric_reduct PF01794.19 EPS25615.1 - 1.5e-19 70.3 13.8 3.7e-19 69.1 13.8 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EPS25615.1 - 5.5e-17 62.3 0.0 7.8e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EPS25615.1 - 1.4e-09 38.0 0.0 2.9e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NDUFB11 PF17250.2 EPS25615.1 - 0.16 12.7 0.0 0.49 11.1 0.0 1.8 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase 11 kDa subunit Sugar_tr PF00083.24 EPS25616.1 - 5.3e-85 286.0 20.4 6e-85 285.8 20.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS25616.1 - 6.1e-16 58.3 26.6 6.1e-16 58.3 26.6 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Dynein_AAA_lid PF17852.1 EPS25616.1 - 0.021 14.9 0.1 0.99 9.5 0.0 2.6 2 0 0 2 2 2 0 Dynein heavy chain AAA lid domain DUF5134 PF17197.4 EPS25616.1 - 0.72 9.7 7.6 0.32 10.9 3.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5134) Amidohydro_2 PF04909.14 EPS25617.1 - 9.1e-31 107.7 0.1 1.1e-30 107.5 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase Pyr_redox_2 PF07992.14 EPS25620.1 - 2.8e-57 194.2 0.8 4.3e-57 193.6 0.8 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EPS25620.1 - 9.7e-34 115.9 0.4 3.3e-33 114.2 0.4 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EPS25620.1 - 3.2e-14 53.2 0.2 3.2e-14 53.2 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EPS25620.1 - 8.7e-13 48.2 0.7 5.7e-12 45.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EPS25620.1 - 7.6e-05 22.0 0.0 0.00013 21.3 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.18 EPS25620.1 - 0.047 13.6 0.3 0.047 13.6 0.3 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.24 EPS25620.1 - 0.097 11.7 3.1 11 5.0 0.0 3.1 3 0 0 3 3 3 0 FAD binding domain Methyltransf_23 PF13489.6 EPS25621.1 - 2.3e-14 53.6 0.0 3.4e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPS25621.1 - 3.3e-09 37.3 0.0 1.1e-08 35.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS25621.1 - 2.1e-05 25.0 0.0 4.9e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPS25621.1 - 3.3e-05 24.6 0.0 0.00024 21.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPS25621.1 - 0.00062 19.6 0.0 0.0092 15.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 EPS25621.1 - 0.0032 17.0 0.0 0.0091 15.5 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_2 PF00891.18 EPS25621.1 - 0.012 14.9 0.0 0.023 14.0 0.0 1.5 1 1 0 1 1 1 0 O-methyltransferase domain PrmA PF06325.13 EPS25621.1 - 0.038 13.4 0.0 0.078 12.4 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 EPS25621.1 - 0.04 13.2 0.0 3.2 7.0 0.0 2.7 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 EPS25621.1 - 0.045 13.3 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain CheR PF01739.18 EPS25621.1 - 0.087 12.3 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Cadherin_C_2 PF16492.5 EPS25623.1 - 0.044 14.5 0.0 0.092 13.5 0.0 1.5 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal p450 PF00067.22 EPS25624.1 - 3.7e-56 190.8 0.0 5e-56 190.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 EPS25625.1 - 1.3e-52 178.8 0.0 7.1e-50 169.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EPS25625.1 - 4e-29 101.7 0.0 1.9e-28 99.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EPS25625.1 - 0.00049 19.5 0.0 0.00073 18.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EPS25625.1 - 0.0012 18.0 0.1 0.0019 17.3 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 EPS25625.1 - 0.015 14.1 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 EPS25625.1 - 0.035 13.1 0.0 0.046 12.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EPS25625.1 - 0.085 12.8 0.2 0.47 10.3 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Dabb PF07876.12 EPS25627.1 - 1.7e-11 44.6 0.0 2.4e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Fungal_trans PF04082.18 EPS25628.1 - 5.7e-18 64.9 0.5 9.7e-18 64.1 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS25628.1 - 3.4e-08 33.5 11.3 6.7e-08 32.5 11.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ldh_2 PF02615.14 EPS25629.1 - 4.2e-120 400.9 0.9 4.7e-120 400.7 0.9 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Asp4 PF16996.5 EPS25629.1 - 0.12 12.2 0.1 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 Accessory secretory protein Sec Asp4 Pkinase PF00069.25 EPS25630.1 - 9.6e-64 215.3 0.0 1.5e-63 214.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS25630.1 - 7.5e-36 123.7 0.0 2.3e-30 105.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EPS25630.1 - 3e-06 26.8 0.0 0.0049 16.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 EPS25630.1 - 0.001 19.1 0.0 0.0028 17.6 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EPS25630.1 - 0.002 17.7 0.0 0.0042 16.7 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 EPS25630.1 - 0.023 13.7 0.1 0.036 13.0 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EPS25630.1 - 0.045 13.1 0.0 0.077 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Senescence PF06911.12 EPS25632.1 - 6.5e-54 183.0 5.0 9.3e-54 182.5 5.0 1.2 1 0 0 1 1 1 1 Senescence-associated protein Cupin_2 PF07883.11 EPS25632.1 - 0.11 12.2 0.1 0.32 10.7 0.1 1.7 1 0 0 1 1 1 0 Cupin domain Dus PF01207.17 EPS25633.1 - 6.2e-40 137.2 0.0 1.4e-28 99.9 0.0 2.9 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH_4 PF18044.1 EPS25633.1 - 0.00022 20.9 0.4 0.00022 20.9 0.4 2.6 2 0 0 2 2 2 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EPS25633.1 - 0.04 14.0 0.7 0.04 14.0 0.7 2.4 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH PF00642.24 EPS25633.1 - 0.06 13.3 0.3 0.06 13.3 0.3 2.3 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Cytomega_UL84 PF06284.11 EPS25633.1 - 0.72 8.3 3.6 3.2 6.1 1.5 2.1 1 1 1 2 2 2 0 Cytomegalovirus UL84 protein Torus PF16131.5 EPS25633.1 - 1.7 9.4 11.3 8.8 7.1 0.5 3.3 2 1 1 3 3 3 0 Torus domain Bap31 PF05529.12 EPS25634.1 - 1.2e-48 164.4 8.7 1.6e-48 164.0 8.7 1.1 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 EPS25634.1 - 4.9e-15 55.3 5.5 9.3e-15 54.4 5.5 1.5 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain DivIC PF04977.15 EPS25634.1 - 0.0001 22.0 3.0 0.014 15.2 0.2 3.3 3 1 0 3 3 3 2 Septum formation initiator SlyX PF04102.12 EPS25634.1 - 0.0075 16.9 1.1 0.022 15.4 0.2 2.2 3 0 0 3 3 3 1 SlyX FlxA PF14282.6 EPS25634.1 - 0.011 15.7 2.0 0.022 14.7 2.0 1.5 1 1 0 1 1 1 0 FlxA-like protein Spc7 PF08317.11 EPS25634.1 - 0.03 13.2 1.9 0.042 12.7 1.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Csm1_N PF18504.1 EPS25634.1 - 0.033 14.5 0.7 0.061 13.7 0.7 1.5 1 0 0 1 1 1 0 Csm1 N-terminal domain TMF_DNA_bd PF12329.8 EPS25634.1 - 0.035 14.1 3.3 0.072 13.1 3.3 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding HALZ PF02183.18 EPS25634.1 - 0.044 14.0 0.6 0.098 12.9 0.5 1.7 1 1 0 1 1 1 0 Homeobox associated leucine zipper GIT_CC PF16559.5 EPS25634.1 - 0.05 13.5 0.2 0.097 12.6 0.2 1.4 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor bZIP_1 PF00170.21 EPS25634.1 - 0.45 10.6 4.8 2.1 8.5 1.1 2.4 2 1 0 2 2 2 0 bZIP transcription factor MMM1 PF10296.9 EPS25635.1 - 8.3e-06 25.1 0.0 1.5e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 FAP PF07174.11 EPS25635.1 - 0.2 11.1 4.3 0.29 10.5 4.3 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) SelP_N PF04592.14 EPS25635.1 - 0.27 10.6 5.2 0.8 9.1 5.1 1.7 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Dehydrin PF00257.19 EPS25638.1 - 0.18 12.3 1.9 0.23 12.0 1.9 1.1 1 0 0 1 1 1 0 Dehydrin zf-C2H2 PF00096.26 EPS25640.1 - 2.4e-05 24.6 10.2 0.071 13.6 1.5 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 EPS25640.1 - 3.4e-05 24.1 0.6 0.024 14.8 0.0 2.2 2 0 0 2 2 2 2 Aberrant zinc-finger zf-C2H2_4 PF13894.6 EPS25640.1 - 0.00014 22.4 11.8 0.03 15.1 1.1 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EPS25640.1 - 0.014 15.6 1.0 1.2 9.5 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 EPS25640.1 - 0.02 15.3 0.5 0.02 15.3 0.5 3.3 3 0 0 3 3 3 0 Zinc-finger double domain DUF4719 PF15843.5 EPS25640.1 - 0.022 14.9 0.7 0.41 10.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4719) TFIIA PF03153.13 EPS25642.1 - 1.2e-75 256.2 42.5 6.7e-75 253.6 42.5 2.4 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit ANAPC4_WD40 PF12894.7 EPS25643.1 - 4.4e-16 59.0 4.2 6e-06 26.5 0.1 4.3 2 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EPS25643.1 - 7.7e-14 51.9 19.7 0.00048 20.9 0.1 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EPS25643.1 - 9.6e-06 24.8 0.0 0.00057 19.0 0.0 2.9 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EPS25643.1 - 0.00045 20.2 0.3 0.045 13.6 0.1 2.6 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Hc1 PF07432.13 EPS25643.1 - 5 7.5 10.2 11 6.4 10.2 1.6 1 0 0 1 1 1 0 Histone H1-like protein Hc1 Kelch_5 PF13854.6 EPS25644.1 - 3.9e-27 93.8 0.6 5.3e-06 26.3 0.0 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_4 PF13418.6 EPS25644.1 - 2.3e-26 91.5 9.8 3.5e-06 26.9 0.0 5.5 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 EPS25644.1 - 1.5e-21 75.9 3.2 5.6e-05 23.3 0.1 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 EPS25644.1 - 1.7e-21 75.5 0.0 6e-06 25.7 0.0 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_2 PF07646.15 EPS25644.1 - 1.8e-20 72.1 1.2 7.9e-06 25.6 0.1 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.6 EPS25644.1 - 1.6e-19 69.7 5.9 7.3e-08 32.5 0.1 5.5 5 0 0 5 5 5 4 Galactose oxidase, central domain BTB PF00651.31 EPS25644.1 - 2.7e-09 37.2 0.1 5.2e-09 36.3 0.1 1.4 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 EPS25644.1 - 0.047 13.8 0.0 0.12 12.5 0.0 1.7 1 1 0 1 1 1 0 BTB And C-terminal Kelch bPH_6 PF10756.9 EPS25644.1 - 0.079 13.1 0.0 0.27 11.4 0.0 1.9 1 0 0 1 1 1 0 Bacterial PH domain Glyco_hydro_1 PF00232.18 EPS25645.1 - 2.4e-154 514.1 0.0 2.9e-154 513.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 AID PF18767.1 EPS25645.1 - 0.12 12.3 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Activation induced deaminase Sel1 PF08238.12 EPS25646.1 - 8.3e-32 108.9 49.2 5.4e-07 30.1 1.4 12.0 12 1 1 13 13 13 8 Sel1 repeat WD40 PF00400.32 EPS25647.1 - 3.4e-16 59.3 6.9 3.6e-05 24.4 0.3 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS25647.1 - 3.1e-11 43.4 0.6 0.0085 16.4 0.0 4.1 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EPS25647.1 - 1.5e-05 25.0 0.1 0.068 13.0 0.0 3.0 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 EPS25647.1 - 0.045 12.3 0.0 0.098 11.2 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain RNA_pol_Rpb1_1 PF04997.12 EPS25648.1 - 2e-111 372.3 0.0 3.2e-111 371.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 EPS25648.1 - 4.9e-103 344.2 0.1 7.6e-103 343.6 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EPS25648.1 - 5.6e-76 254.4 0.1 2.3e-75 252.4 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 EPS25648.1 - 8.3e-64 214.9 0.4 1.7e-63 213.9 0.4 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 EPS25648.1 - 4.3e-45 153.5 0.0 1.1e-44 152.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 EPS25648.1 - 7.9e-45 152.2 6.1 1.7e-44 151.0 6.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 EPS25648.1 - 1.7e-36 124.4 0.1 4.8e-36 123.0 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 EPS25648.1 - 3.3e-05 24.0 157.8 0.3 11.5 3.8 13.1 7 1 5 13 13 13 9 RNA polymerase Rpb1 C-terminal repeat WD40 PF00400.32 EPS25649.1 - 2e-13 50.5 0.2 0.041 14.8 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS25649.1 - 5.7e-05 23.3 0.1 0.089 13.1 0.1 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EPS25649.1 - 0.053 12.3 0.0 0.29 9.8 0.0 2.1 2 1 0 3 3 3 0 Nup133 N terminal like Methyltransf_23 PF13489.6 EPS25650.1 - 9.6e-17 61.3 0.0 1.6e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPS25650.1 - 1.6e-08 35.1 0.0 4.6e-08 33.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPS25650.1 - 1e-06 29.4 0.0 2.5e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPS25650.1 - 2.2e-05 24.3 0.0 3.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS25650.1 - 2.3e-05 24.9 0.0 6.9e-05 23.4 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain FtsJ PF01728.19 EPS25650.1 - 0.0003 21.0 0.0 0.0005 20.2 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.14 EPS25650.1 - 0.00039 20.0 0.0 0.00071 19.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 EPS25650.1 - 0.0016 18.0 0.0 0.0028 17.1 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 EPS25650.1 - 0.014 14.8 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 EPS25650.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_16 PF10294.9 EPS25650.1 - 0.14 11.9 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Cyclin PF08613.11 EPS25651.1 - 2.5e-39 135.2 0.7 3.5e-24 86.0 0.3 2.7 2 0 0 2 2 2 2 Cyclin Proteasome PF00227.26 EPS25652.1 - 1.4e-47 161.6 0.2 1.7e-47 161.4 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit Hydrolase_4 PF12146.8 EPS25653.1 - 2.1e-18 66.5 0.0 5.1e-13 48.9 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EPS25653.1 - 5.4e-13 49.2 0.0 1.9e-09 37.6 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPS25653.1 - 1e-07 32.8 0.0 1e-06 29.6 0.0 2.3 2 1 1 3 3 3 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EPS25653.1 - 1.3e-05 24.8 0.0 4e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.13 EPS25653.1 - 2.2e-05 24.2 0.0 5.6e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) AXE1 PF05448.12 EPS25653.1 - 0.00052 18.8 0.1 0.83 8.3 0.0 2.7 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) Thioesterase PF00975.20 EPS25653.1 - 0.0016 18.6 0.0 0.0027 17.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain DLH PF01738.18 EPS25653.1 - 0.0048 16.5 0.0 0.73 9.3 0.0 2.3 2 0 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.11 EPS25653.1 - 0.01 15.8 0.0 0.76 9.6 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.20 EPS25653.1 - 0.011 15.4 0.0 0.044 13.4 0.0 1.8 2 0 0 2 2 2 0 Putative esterase DUF818 PF05677.12 EPS25653.1 - 0.015 14.3 0.0 0.02 13.8 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Peptidase_S15 PF02129.18 EPS25653.1 - 0.016 14.8 0.0 0.52 9.9 0.0 2.1 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.13 EPS25653.1 - 0.05 13.5 0.1 0.09 12.6 0.1 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold LIDHydrolase PF10230.9 EPS25653.1 - 0.05 13.1 0.0 0.33 10.5 0.0 1.9 1 1 0 2 2 2 0 Lipid-droplet associated hydrolase Abhydrolase_5 PF12695.7 EPS25653.1 - 0.059 13.1 0.0 0.17 11.7 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Lipase_3 PF01764.25 EPS25653.1 - 0.063 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF1057 PF06342.12 EPS25653.1 - 0.088 11.8 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) PGAP1 PF07819.13 EPS25653.1 - 0.19 11.4 0.0 2.4 7.8 0.0 2.2 1 1 1 2 2 2 0 PGAP1-like protein R3H PF01424.22 EPS25654.1 - 1.6e-09 37.6 0.0 1.6e-09 37.6 0.0 2.8 2 1 0 2 2 2 1 R3H domain zf-NF-X1 PF01422.17 EPS25654.1 - 2.4e-06 27.5 68.7 4.2e-05 23.5 13.1 13.4 15 1 0 15 15 15 7 NF-X1 type zinc finger TGS PF02824.21 EPS25654.1 - 0.12 12.4 0.0 0.3 11.2 0.0 1.6 1 0 0 1 1 1 0 TGS domain RIFIN PF02009.16 EPS25654.1 - 0.19 11.6 12.4 0.27 11.1 0.8 2.4 2 0 0 2 2 2 0 Rifin Spore_GerAC PF05504.11 EPS25654.1 - 0.56 10.4 4.6 1 9.5 4.6 1.4 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal Peptidase_S64 PF08192.11 EPS25654.1 - 0.73 8.3 9.3 1 7.7 9.3 1.1 1 0 0 1 1 1 0 Peptidase family S64 WAC_Acf1_DNA_bd PF10537.9 EPS25654.1 - 1.4 9.5 6.4 3.6 8.2 6.4 1.6 1 0 0 1 1 1 0 ATP-utilising chromatin assembly and remodelling N-terminal Spore_III_AF PF09581.10 EPS25654.1 - 2.9 7.9 9.6 5.2 7.1 9.6 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) zf-LYAR PF08790.11 EPS25655.1 - 2e-14 53.2 2.3 2e-14 53.2 2.3 2.0 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger Evr1_Alr PF04777.13 EPS25656.1 - 9.3e-27 93.4 0.4 9.3e-27 93.4 0.4 1.5 1 1 1 2 2 2 1 Erv1 / Alr family APOBEC4 PF18775.1 EPS25656.1 - 0.015 15.4 0.1 0.031 14.4 0.1 1.5 1 0 0 1 1 1 0 APOBEC4 APOBEC1 PF18769.1 EPS25656.1 - 0.089 13.1 0.1 0.16 12.2 0.1 1.5 1 0 0 1 1 1 0 APOBEC1 Glyco_hydro_92 PF07971.12 EPS25657.1 - 9.6e-144 479.7 0.1 1.2e-143 479.5 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EPS25657.1 - 8.4e-64 215.7 0.3 1.3e-63 215.1 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain MFS_1 PF07690.16 EPS25658.1 - 8.5e-15 54.5 63.6 4.5e-11 42.3 40.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.16 EPS25660.1 - 5.6e-47 160.4 59.0 5.1e-46 157.2 38.7 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS25660.1 - 5.9e-12 45.2 6.3 5.9e-12 45.2 6.3 2.7 1 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 EPS25660.1 - 2.3e-07 30.5 4.6 2.3e-07 30.5 4.6 1.8 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF2583 PF10762.9 EPS25660.1 - 0.056 13.9 3.5 0.33 11.4 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2583) UL42 PF17638.2 EPS25660.1 - 0.24 11.4 0.1 0.24 11.4 0.1 2.3 2 0 0 2 2 2 0 HCMV UL42 G_glu_transpept PF01019.21 EPS25661.1 - 1e-170 568.9 0.1 1.3e-170 568.6 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase HhH-GPD PF00730.25 EPS25662.1 - 9.8e-08 32.4 0.0 2.9e-07 30.9 0.0 1.8 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein ADH_N PF08240.12 EPS25664.1 - 6.6e-19 67.8 4.4 1.5e-18 66.6 4.4 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPS25664.1 - 1.9e-11 44.1 0.2 3.9e-11 43.0 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EPS25664.1 - 1.4e-05 24.5 0.1 0.00054 19.3 0.0 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EPS25664.1 - 8.2e-05 22.0 0.1 0.00017 21.0 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 EPS25664.1 - 0.003 18.4 0.0 0.03 15.1 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_2 PF03446.15 EPS25664.1 - 0.0083 16.3 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 EPS25664.1 - 0.11 12.4 0.2 0.17 11.7 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EPS25664.1 - 0.13 12.7 0.0 1.9 9.0 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding Git3 PF11710.8 EPS25665.1 - 2.5e-36 125.4 19.3 3.1e-36 125.0 18.3 1.6 1 1 1 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 EPS25665.1 - 2.3e-13 50.0 1.4 6e-13 48.7 0.0 2.4 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.11 EPS25665.1 - 0.0019 17.4 20.0 0.0022 17.2 18.9 1.6 1 1 1 2 2 2 1 Slime mold cyclic AMP receptor Glyco_hydro_76 PF03663.14 EPS25666.1 - 1.3e-41 143.4 18.7 1.8e-41 142.9 18.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EPS25666.1 - 2.1e-06 27.1 2.2 0.00088 18.4 0.0 2.5 1 1 1 2 2 2 2 Glycosyl Hydrolase Family 88 Glyco_hydro_47 PF01532.20 EPS25666.1 - 0.031 13.2 0.0 0.13 11.1 0.0 1.9 1 1 0 2 2 2 0 Glycosyl hydrolase family 47 GST_N PF02798.20 EPS25667.1 - 3.5e-11 43.3 0.0 6.9e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EPS25667.1 - 2.3e-08 34.2 0.0 7.1e-08 32.7 0.0 1.8 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EPS25667.1 - 7.6e-08 32.7 0.0 1.8e-07 31.4 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EPS25667.1 - 3.3e-05 23.8 0.0 6.1e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EPS25667.1 - 7.5e-05 22.9 0.0 0.00011 22.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EPS25667.1 - 0.00051 20.2 0.1 0.00078 19.6 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ACC_central PF08326.12 EPS25667.1 - 0.032 12.4 0.2 0.042 12.1 0.2 1.1 1 0 0 1 1 1 0 Acetyl-CoA carboxylase, central region DUF2834 PF11196.8 EPS25668.1 - 0.018 15.4 4.2 0.018 15.4 4.2 4.1 3 2 2 5 5 5 0 Protein of unknown function (DUF2834) Beta-lactamase PF00144.24 EPS25669.1 - 2e-62 211.4 0.0 2.6e-62 211.0 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Xan_ur_permease PF00860.20 EPS25670.1 - 1.8e-22 79.6 34.5 1.4e-21 76.7 32.1 2.7 2 1 0 2 2 2 1 Permease family DUF543 PF04418.12 EPS25670.1 - 4.5 7.3 6.8 89 3.2 0.3 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF543) DUF2207 PF09972.9 EPS25671.1 - 0.086 11.6 0.0 0.086 11.6 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PDR_CDR PF06422.12 EPS25671.1 - 0.13 12.1 0.1 0.17 11.8 0.1 1.2 1 0 0 1 1 1 0 CDR ABC transporter Tad PF13400.6 EPS25671.1 - 4.8 7.6 6.0 6.9 7.1 6.0 1.2 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like Calici_coat_C PF08435.11 EPS25672.1 - 0.22 11.0 0.0 0.25 10.8 0.0 1.1 1 0 0 1 1 1 0 Calicivirus coat protein C-terminal Sugar_tr PF00083.24 EPS25673.1 - 8.6e-81 272.1 25.2 1.1e-80 271.8 25.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS25673.1 - 3.8e-31 108.3 28.3 3.8e-31 108.3 28.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily CorA PF01544.18 EPS25673.1 - 0.8 9.0 2.4 2 7.7 2.4 1.6 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein 14-3-3 PF00244.20 EPS25674.1 - 1.2e-08 34.8 0.0 2.1e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 14-3-3 protein ArAE_2_N PF10337.9 EPS25675.1 - 4.5e-70 237.0 4.6 3.9e-52 177.9 0.1 3.9 2 1 1 3 3 3 3 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 EPS25675.1 - 1.6e-16 60.6 13.3 1.6e-16 60.6 13.3 3.9 2 2 1 3 3 3 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 EPS25675.1 - 1e-13 51.6 0.0 7.3e-13 48.9 0.0 2.2 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 DUF5315 PF17242.2 EPS25675.1 - 0.17 11.7 0.1 0.36 10.7 0.1 1.5 1 0 0 1 1 1 0 Disordered region of unknown function (DUF5315) DPBB_1 PF03330.18 EPS25676.1 - 7.5e-07 29.3 0.0 1.3e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 EPS25676.1 - 0.0077 16.1 0.2 0.011 15.6 0.2 1.3 1 0 0 1 1 1 1 Barwin family Sugar_tr PF00083.24 EPS25677.1 - 3.2e-123 411.9 23.2 3.6e-123 411.8 23.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS25677.1 - 3.6e-23 82.0 45.8 9.9e-23 80.6 27.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily EMP24_GP25L PF01105.24 EPS25679.1 - 6.8e-51 172.8 0.1 8.1e-51 172.5 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Rootletin PF15035.6 EPS25680.1 - 0.00016 21.8 4.0 0.00016 21.8 4.0 5.8 1 1 5 6 6 6 1 Ciliary rootlet component, centrosome cohesion PAM2 PF07145.15 EPS25680.1 - 0.021 14.5 6.5 1.8 8.5 1.9 2.9 2 0 0 2 2 2 0 Ataxin-2 C-terminal region SspB PF04386.13 EPS25680.1 - 0.3 11.0 4.7 0.33 10.8 1.2 3.0 2 0 0 2 2 2 0 Stringent starvation protein B TSC22 PF01166.18 EPS25680.1 - 0.92 9.9 15.5 2 8.8 0.1 5.0 5 0 0 5 5 5 0 TSC-22/dip/bun family Fib_alpha PF08702.10 EPS25680.1 - 7 6.8 34.1 0.32 11.2 4.0 5.3 4 1 0 5 5 5 0 Fibrinogen alpha/beta chain family Glyco_hydro_17 PF00332.18 EPS25681.1 - 1.2e-37 130.2 0.2 3.1e-37 128.8 0.2 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 MRP-S26 PF14943.6 EPS25681.1 - 0.13 12.2 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S26 GLE1 PF07817.13 EPS25682.1 - 4.1e-50 170.3 0.0 1e-49 169.1 0.0 1.6 1 1 0 1 1 1 1 GLE1-like protein Ndc1_Nup PF09531.10 EPS25682.1 - 0.33 9.6 8.1 0.43 9.2 8.1 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CCDC71L PF15374.6 EPS25682.1 - 0.46 9.7 16.1 0.65 9.2 16.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 71L SRP-alpha_N PF04086.13 EPS25682.1 - 1.6 8.6 22.9 2.2 8.1 22.9 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Chon_Sulph_att PF06566.11 EPS25682.1 - 2.7 7.8 3.8 5 6.9 3.8 1.4 1 0 0 1 1 1 0 Chondroitin sulphate attachment domain SOBP PF15279.6 EPS25682.1 - 3.3 8.2 4.8 5.6 7.5 4.8 1.5 1 0 0 1 1 1 0 Sine oculis-binding protein Presenilin PF01080.17 EPS25682.1 - 3.8 6.2 18.8 6.2 5.5 18.8 1.4 1 0 0 1 1 1 0 Presenilin LAP1C PF05609.12 EPS25682.1 - 5.2 6.0 21.7 7.2 5.6 21.7 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Draxin PF15550.6 EPS25682.1 - 8.8 6.1 20.2 12 5.6 20.2 1.2 1 0 0 1 1 1 0 Draxin DUF4045 PF13254.6 EPS25682.1 - 8.8 5.8 25.8 12 5.4 25.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) RNB PF00773.19 EPS25685.1 - 4.5e-86 289.1 0.1 1.3e-85 287.6 0.0 1.8 2 0 0 2 2 2 1 RNB domain OB_Dis3 PF17849.1 EPS25685.1 - 7.3e-26 90.0 0.0 1.8e-25 88.8 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 EPS25685.1 - 2.3e-25 88.7 0.0 7.5e-25 87.1 0.0 2.0 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal Rrp44_CSD1 PF17216.3 EPS25685.1 - 1.9e-05 24.4 0.0 3.7e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Rrp44-like cold shock domain CSD2 PF17876.1 EPS25685.1 - 2.8e-05 24.2 0.0 0.015 15.5 0.0 2.7 2 0 0 2 2 2 2 Cold shock domain Rrp44_S1 PF17215.3 EPS25685.1 - 0.16 12.0 0.0 0.71 9.9 0.0 2.1 2 0 0 2 2 2 0 S1 domain UQ_con PF00179.26 EPS25686.1 - 4.2e-36 123.7 0.0 7e-36 122.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EPS25686.1 - 0.0042 16.8 0.0 0.0067 16.1 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B MMgT PF10270.9 EPS25688.1 - 8.6e-36 122.3 0.0 9.9e-36 122.1 0.0 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter EF1_GNE PF00736.19 EPS25689.1 - 5e-34 116.4 2.6 1e-33 115.3 2.6 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 EPS25689.1 - 4.1e-12 46.3 4.4 4.1e-12 46.3 4.4 3.3 4 0 0 4 4 4 1 Eukaryotic elongation factor 1 beta central acidic region GST_C PF00043.25 EPS25689.1 - 0.00013 22.1 1.5 0.0003 21.0 0.1 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EPS25689.1 - 0.00018 21.6 0.3 0.00038 20.6 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EPS25689.1 - 0.0007 19.6 0.8 0.016 15.3 0.8 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DNA_pol3_a_NII PF11490.8 EPS25689.1 - 1.5 8.7 6.2 1.7 8.5 0.2 2.3 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II AAA_2 PF07724.14 EPS25690.1 - 7.6e-45 153.1 0.0 7.1e-44 149.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EPS25690.1 - 1.7e-34 117.8 2.1 1.7e-34 117.8 2.1 2.6 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 EPS25690.1 - 4.2e-26 90.8 0.3 1.5e-25 89.0 0.3 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 EPS25690.1 - 3.9e-19 69.4 0.0 1.4e-10 41.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EPS25690.1 - 1.3e-13 51.1 0.7 8.4e-09 35.5 0.0 3.4 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EPS25690.1 - 1.6e-09 38.4 8.6 0.00025 21.5 0.4 4.4 3 2 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 EPS25690.1 - 5.1e-08 33.3 4.6 0.0088 16.3 0.0 4.3 3 2 0 3 3 3 2 AAA domain Sigma54_activat PF00158.26 EPS25690.1 - 9.6e-08 31.9 0.4 4.3e-05 23.3 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 EPS25690.1 - 2.3e-06 27.7 0.0 0.022 14.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain TniB PF05621.11 EPS25690.1 - 2.5e-06 27.1 0.0 0.0033 16.8 0.0 3.6 3 1 0 3 3 2 1 Bacterial TniB protein AAA_7 PF12775.7 EPS25690.1 - 9.4e-06 25.3 0.1 0.026 14.1 0.0 2.5 2 1 0 2 2 2 2 P-loop containing dynein motor region NACHT PF05729.12 EPS25690.1 - 1.6e-05 24.9 0.0 0.11 12.4 0.0 2.7 2 0 0 2 2 2 2 NACHT domain ATPase_2 PF01637.18 EPS25690.1 - 3.4e-05 23.9 5.6 0.62 9.9 0.1 4.0 3 2 1 4 4 3 2 ATPase domain predominantly from Archaea AAA_28 PF13521.6 EPS25690.1 - 4.7e-05 23.7 0.1 0.058 13.6 0.0 3.5 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 EPS25690.1 - 0.0001 22.1 0.1 0.64 9.7 0.0 2.6 2 1 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 EPS25690.1 - 0.00025 21.6 1.1 0.68 10.5 0.0 3.0 3 0 0 3 3 2 2 AAA domain SRP54 PF00448.22 EPS25690.1 - 0.00037 20.2 0.1 0.065 12.9 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_24 PF13479.6 EPS25690.1 - 0.00041 20.1 0.0 0.34 10.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 EPS25690.1 - 0.0011 19.0 0.2 4.9 7.1 0.0 3.4 2 1 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EPS25690.1 - 0.0011 18.7 1.9 0.12 12.1 0.1 3.9 3 1 1 4 4 3 1 AAA domain AAA_19 PF13245.6 EPS25690.1 - 0.0012 19.2 0.5 0.17 12.2 0.1 3.5 3 1 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 EPS25690.1 - 0.0014 19.0 0.0 0.83 10.1 0.0 2.8 2 1 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.21 EPS25690.1 - 0.0022 17.4 0.1 2.7 7.3 0.1 3.2 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 EPS25690.1 - 0.0027 16.9 0.4 0.19 10.9 0.3 3.1 2 1 0 2 2 2 1 Protein of unknown function (DUF815) TsaE PF02367.17 EPS25690.1 - 0.0038 17.2 0.1 2.6 8.1 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE TrwB_AAD_bind PF10412.9 EPS25690.1 - 0.0056 15.6 0.1 0.66 8.8 0.0 2.9 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain RsgA_GTPase PF03193.16 EPS25690.1 - 0.0067 16.4 0.0 2.1 8.2 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase Zeta_toxin PF06414.12 EPS25690.1 - 0.0073 15.6 0.0 0.79 9.0 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin Roc PF08477.13 EPS25690.1 - 0.0075 16.5 0.0 0.77 10.0 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 EPS25690.1 - 0.0079 16.7 1.9 2.6 8.5 0.0 3.4 3 0 0 3 3 3 1 ABC transporter AAA_33 PF13671.6 EPS25690.1 - 0.0093 16.1 0.1 6.2 7.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF853 PF05872.12 EPS25690.1 - 0.012 14.3 0.1 0.088 11.4 0.0 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) ATP_bind_1 PF03029.17 EPS25690.1 - 0.014 15.2 0.1 0.26 11.0 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 EPS25690.1 - 0.016 15.0 0.0 0.64 9.8 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 EPS25690.1 - 0.016 14.8 0.1 0.25 10.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EPS25690.1 - 0.036 14.0 0.1 0.42 10.5 0.0 2.5 2 0 0 2 2 2 0 NTPase RuvB_N PF05496.12 EPS25690.1 - 0.049 13.4 0.1 11 5.8 0.0 3.5 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_6 PF12774.7 EPS25690.1 - 0.11 11.5 0.0 3 6.7 0.0 2.3 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region cobW PF02492.19 EPS25690.1 - 0.12 12.0 0.1 12 5.5 0.0 3.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.6 EPS25690.1 - 0.12 12.1 1.5 0.73 9.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system UvrD-helicase PF00580.21 EPS25690.1 - 0.14 11.6 4.1 0.38 10.2 0.1 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_29 PF13555.6 EPS25690.1 - 0.2 11.4 0.1 16 5.3 0.0 2.9 3 0 0 3 3 2 0 P-loop containing region of AAA domain LTXXQ PF07813.12 EPS25690.1 - 0.22 12.3 6.6 0.046 14.4 2.2 2.1 2 0 0 2 2 1 0 LTXXQ motif family protein CENP-F_leu_zip PF10473.9 EPS25690.1 - 0.27 11.3 16.9 0.23 11.5 8.0 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMCO5 PF14992.6 EPS25690.1 - 0.39 10.2 9.9 0.71 9.4 9.9 1.3 1 0 0 1 1 1 0 TMCO5 family GAS PF13851.6 EPS25690.1 - 0.51 9.7 11.7 1.1 8.6 11.7 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding OEP PF02321.18 EPS25690.1 - 2.8 7.7 11.2 6.8 6.5 11.2 1.6 1 0 0 1 1 1 0 Outer membrane efflux protein DivIC PF04977.15 EPS25690.1 - 3.1 7.6 13.7 1.4 8.8 5.8 2.9 2 1 1 3 3 2 0 Septum formation initiator DUF2968 PF11180.8 EPS25690.1 - 8.3 6.0 12.2 31 4.1 12.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) MutS_V PF00488.21 EPS25691.1 - 5.5e-51 173.3 1.0 8.4e-51 172.7 0.3 1.7 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 EPS25691.1 - 1.1e-15 58.4 0.2 2.5e-15 57.2 0.1 1.7 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 EPS25691.1 - 0.003 17.9 0.0 0.0067 16.7 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV Sas10 PF09368.10 EPS25692.1 - 3.4e-29 101.1 9.4 3.4e-29 101.1 9.4 3.0 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 EPS25692.1 - 5e-14 52.7 0.0 3.8e-13 49.8 0.0 2.6 1 0 0 1 1 1 1 Sas10/Utp3/C1D family adh_short PF00106.25 EPS25693.1 - 2.5e-28 98.9 0.0 3.7e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS25693.1 - 2e-16 60.3 0.0 4.4e-16 59.2 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPS25693.1 - 8.5e-11 42.1 0.0 2e-10 40.9 0.0 1.6 1 1 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EPS25693.1 - 2.6e-07 30.4 0.1 9.2e-07 28.6 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EPS25693.1 - 4e-05 23.2 0.1 9.9e-05 21.9 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EPS25693.1 - 0.0031 17.4 0.2 0.011 15.6 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_7 PF13241.6 EPS25693.1 - 0.015 15.8 0.0 0.029 14.8 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.19 EPS25693.1 - 0.019 14.3 0.1 0.035 13.4 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain F420_oxidored PF03807.17 EPS25693.1 - 0.029 15.0 0.0 0.087 13.4 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.15 EPS25693.1 - 0.032 13.4 0.0 0.05 12.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 EPS25693.1 - 0.046 13.8 0.0 0.078 13.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EPS25693.1 - 0.071 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain FA_hydroxylase PF04116.13 EPS25694.1 - 1.3e-15 57.9 7.2 1.3e-15 57.9 7.2 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Ribosomal_L6e PF01159.19 EPS25695.1 - 4.9e-40 136.5 1.1 8.2e-40 135.8 1.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e Proteasom_Rpn13 PF04683.13 EPS25697.1 - 4.4e-27 94.5 0.0 6.8e-27 93.8 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 EPS25697.1 - 4.4e-12 46.2 3.4 1.5e-10 41.3 3.4 2.4 1 1 0 1 1 1 1 UCH-binding domain Ion_trans PF00520.31 EPS25698.1 - 8.7e-129 427.9 82.4 6.3e-42 143.5 3.9 4.8 4 1 0 4 4 4 4 Ion transport protein EF-hand_1 PF00036.32 EPS25698.1 - 0.00043 19.6 0.0 0.0018 17.7 0.0 2.1 2 0 0 2 2 2 1 EF hand GPHH PF16905.5 EPS25698.1 - 0.00054 19.7 0.0 0.0013 18.4 0.0 1.7 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated EF-hand_7 PF13499.6 EPS25698.1 - 0.0013 19.2 0.1 0.16 12.4 0.0 3.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EPS25698.1 - 0.0015 18.3 0.0 0.035 14.0 0.0 3.1 2 0 0 2 2 2 1 EF-hand domain PKD_channel PF08016.12 EPS25698.1 - 1.4 7.5 58.0 0.65 8.6 2.6 7.0 6 1 1 7 7 7 0 Polycystin cation channel Hamartin PF04388.12 EPS25699.1 - 0.27 9.9 5.9 0.25 10.0 5.9 1.1 1 0 0 1 1 1 0 Hamartin protein SET PF00856.28 EPS25700.1 - 1.9e-19 70.7 0.0 4.7e-19 69.4 0.0 1.7 1 0 0 1 1 1 1 SET domain Pre-SET PF05033.16 EPS25700.1 - 8.2e-07 29.7 1.4 8.2e-07 29.7 1.4 2.2 3 0 0 3 3 3 1 Pre-SET motif CSRNP_N PF16019.5 EPS25700.1 - 3 7.7 8.8 7.2 6.5 8.8 1.6 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Pkinase PF00069.25 EPS25701.1 - 3.6e-69 233.1 0.0 5.2e-69 232.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS25701.1 - 5.2e-40 137.4 0.0 9.8e-40 136.5 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 EPS25701.1 - 7.3e-17 60.9 0.4 1.3e-16 60.1 0.4 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.14 EPS25701.1 - 1.2e-05 24.8 0.0 2.2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EPS25701.1 - 2.2e-05 23.9 0.0 0.00059 19.2 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EPS25701.1 - 2.4e-05 23.5 0.0 3.8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EPS25701.1 - 0.001 19.0 0.0 0.0084 16.1 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EPS25701.1 - 0.064 12.8 0.2 0.21 11.2 0.2 1.8 1 1 0 1 1 1 0 RIO1 family YrbL-PhoP_reg PF10707.9 EPS25701.1 - 0.08 12.5 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL WaaY PF06176.11 EPS25701.1 - 0.19 11.3 0.0 0.3 10.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Amidohydro_3 PF07969.11 EPS25703.1 - 0.0029 17.2 0.5 0.049 13.1 0.3 2.5 2 1 0 2 2 2 1 Amidohydrolase family XFP_N PF09364.10 EPS25704.1 - 1.7e-174 579.9 0.0 2.2e-174 579.5 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.15 EPS25704.1 - 7.6e-82 273.3 0.0 1.4e-81 272.5 0.0 1.4 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.10 EPS25704.1 - 6e-80 267.5 0.0 9.3e-80 266.9 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain Fungal_trans PF04082.18 EPS25705.1 - 0.00011 21.4 0.1 0.00018 20.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glycos_transf_2 PF00535.26 EPS25706.1 - 3.1e-15 56.4 0.0 4.6e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.6 EPS25706.1 - 4.9e-15 56.0 0.7 4.9e-15 56.0 0.7 2.7 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EPS25706.1 - 7.7e-15 55.4 0.1 1.9e-14 54.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EPS25706.1 - 2.8e-07 30.2 0.0 5.1e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 YrhC PF14143.6 EPS25706.1 - 0.0061 16.6 0.2 0.016 15.3 0.2 1.7 1 0 0 1 1 1 1 YrhC-like protein Cellulose_synt PF03552.14 EPS25706.1 - 0.035 12.6 0.2 5.8 5.3 0.0 2.5 1 1 2 3 3 3 0 Cellulose synthase 4HBT PF03061.22 EPS25708.1 - 5.9e-09 36.2 0.0 8.9e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 EPS25708.1 - 0.15 12.5 0.0 0.19 12.2 0.0 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily FA_desaturase PF00487.24 EPS25709.1 - 1.3e-23 84.1 16.5 3e-23 83.0 16.5 1.6 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 EPS25709.1 - 1.3e-06 28.7 0.0 4.1e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3474) TRAPPC10 PF12584.8 EPS25711.1 - 3.3e-36 124.3 0.0 5.8e-36 123.6 0.0 1.4 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Cu_amine_oxid PF01179.20 EPS25712.1 - 7.2e-160 532.4 0.0 9.1e-160 532.1 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 EPS25712.1 - 1e-08 35.3 0.0 2.2e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.16 EPS25712.1 - 6.9e-06 26.4 0.0 1.3e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain adh_short_C2 PF13561.6 EPS25713.1 - 2.1e-41 142.0 0.7 2.1e-41 142.0 0.7 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPS25713.1 - 1.3e-33 116.1 0.5 7e-33 113.7 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_deac_1 PF01522.21 EPS25713.1 - 1.8e-18 66.6 0.0 4.6e-18 65.3 0.0 1.7 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 EPS25713.1 - 6.7e-07 29.2 0.0 2.7e-06 27.2 0.0 2.1 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2334) KR PF08659.10 EPS25713.1 - 0.00018 21.5 0.3 0.001 19.0 0.3 2.2 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EPS25713.1 - 0.00028 20.8 0.0 0.00059 19.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EPS25713.1 - 0.0014 18.1 0.0 0.0028 17.2 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EPS25713.1 - 0.065 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Rad51 PF08423.11 EPS25714.1 - 6.3e-42 143.6 0.0 1.2e-38 132.9 0.0 2.1 2 0 0 2 2 2 2 Rad51 AAA_25 PF13481.6 EPS25714.1 - 1.1e-10 41.4 0.0 2.3e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 EPS25714.1 - 1.1e-08 34.8 0.1 4.6e-08 32.7 0.0 2.0 2 1 0 2 2 2 1 KaiC RecA PF00154.21 EPS25714.1 - 5.6e-06 26.0 0.7 5.9e-05 22.7 0.7 2.0 1 1 0 1 1 1 1 recA bacterial DNA recombination protein AAA_22 PF13401.6 EPS25714.1 - 0.019 15.3 0.0 0.039 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.15 EPS25714.1 - 0.026 13.8 0.6 0.095 12.0 0.6 1.8 1 1 0 1 1 1 0 DnaB-like helicase C terminal domain DUF2075 PF09848.9 EPS25714.1 - 0.028 13.7 0.0 0.045 13.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 EPS25714.1 - 0.1 13.1 0.1 0.26 11.8 0.1 1.6 1 0 0 1 1 1 0 ABC transporter PAXNEB PF05625.11 EPS25714.1 - 0.11 11.7 0.3 0.17 10.9 0.3 1.3 1 0 0 1 1 1 0 PAXNEB protein AAA_24 PF13479.6 EPS25714.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 EPS25714.1 - 0.16 11.4 0.1 0.37 10.2 0.1 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein cobW PF02492.19 EPS25714.1 - 0.17 11.5 0.1 0.3 10.6 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 EPS25714.1 - 0.19 11.5 0.2 0.42 10.4 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 EPS25714.1 - 0.3 11.0 0.9 1.6 8.7 0.9 2.2 1 1 0 1 1 1 0 NACHT domain ER-remodelling PF14755.6 EPS25714.1 - 0.73 10.1 9.5 5.3 7.3 4.1 2.5 2 0 0 2 2 2 0 Intracellular membrane remodeller Velvet PF11754.8 EPS25716.1 - 9.4e-51 173.2 0.1 1.6e-31 110.1 0.0 3.2 2 2 1 3 3 3 2 Velvet factor I_LWEQ PF01608.17 EPS25717.1 - 0.19 11.9 1.3 0.38 11.0 1.3 1.4 1 0 0 1 1 1 0 I/LWEQ domain Sugar_tr PF00083.24 EPS25718.1 - 3.6e-85 286.5 17.5 4.5e-85 286.2 17.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS25718.1 - 2e-22 79.6 35.9 1.1e-19 70.6 20.3 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Cyclase PF04199.13 EPS25722.1 - 1.2e-12 48.3 0.0 2.1e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Putative cyclase LSM14 PF12701.7 EPS25723.1 - 1.2e-28 99.0 0.0 2e-28 98.3 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 EPS25723.1 - 2e-19 70.4 3.6 4.1e-19 69.4 3.6 1.6 1 0 0 1 1 1 1 FDF domain SM-ATX PF14438.6 EPS25723.1 - 3.2e-06 27.2 0.0 6.1e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain API5 PF05918.11 EPS25723.1 - 3.7 6.2 4.4 4.9 5.8 4.4 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) WD40 PF00400.32 EPS25724.1 - 1.8e-25 88.7 4.3 3.6e-05 24.4 0.1 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS25724.1 - 2.3e-06 27.8 0.1 0.6 10.5 0.0 4.1 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EPS25724.1 - 0.021 13.5 0.1 0.45 9.1 0.1 2.6 2 1 0 3 3 3 0 Nucleoporin Nup120/160 Reg_prop PF07494.11 EPS25724.1 - 0.038 14.2 0.0 2.9 8.4 0.0 3.1 2 0 0 2 2 2 0 Two component regulator propeller Sigma70_r1_2 PF00140.20 EPS25724.1 - 2.1 8.5 6.1 4.2 7.5 6.1 1.5 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 Thioredox_DsbH PF03190.15 EPS25725.1 - 5.6e-72 241.0 0.0 9.4e-72 240.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 EPS25725.1 - 2.6e-06 27.5 0.0 5.4e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Glyco_hydro_88 PF07470.13 EPS25725.1 - 0.02 14.0 0.0 4.8 6.2 0.1 2.7 2 1 0 2 2 2 0 Glycosyl Hydrolase Family 88 Glyco_hydro_9 PF00759.19 EPS25725.1 - 0.081 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 Sigma70_r4 PF04545.16 EPS25725.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 Glyco_hydro_127 PF07944.12 EPS25725.1 - 0.14 10.6 0.1 2 6.8 0.1 2.2 2 0 0 2 2 2 0 Beta-L-arabinofuranosidase, GH127 C5-epim_C PF06662.13 EPS25725.1 - 0.15 11.5 0.4 8.2 5.9 0.0 2.5 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus CAP PF00188.26 EPS25727.1 - 1.1e-16 61.8 0.1 1.9e-16 61.1 0.1 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family FAD_binding_3 PF01494.19 EPS25728.1 - 6.3e-22 78.3 0.0 9.7e-21 74.4 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EPS25728.1 - 3.8e-05 23.1 0.2 0.003 16.8 0.0 2.1 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EPS25728.1 - 0.0023 17.0 0.0 0.0033 16.5 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.6 EPS25728.1 - 0.0073 16.5 0.3 0.019 15.2 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EPS25728.1 - 0.022 14.0 0.7 0.47 9.7 0.3 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EPS25728.1 - 0.094 12.7 0.2 2.3 8.2 0.2 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 EPS25728.1 - 0.14 12.8 0.4 0.33 11.5 0.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Carn_acyltransf PF00755.20 EPS25730.1 - 5.9e-210 698.8 0.0 9.3e-210 698.2 0.0 1.3 1 1 0 1 1 1 1 Choline/Carnitine o-acyltransferase Ligase_CoA PF00549.19 EPS25732.1 - 3.2e-35 121.2 2.0 1.4e-17 64.0 0.1 2.4 2 0 0 2 2 2 2 CoA-ligase CoA_binding PF02629.19 EPS25732.1 - 2.3e-17 63.5 0.2 5.7e-17 62.2 0.2 1.7 1 0 0 1 1 1 1 CoA binding domain Succ_CoA_lig PF13607.6 EPS25732.1 - 1.1e-10 41.4 0.1 3.8e-09 36.5 0.0 2.5 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 EPS25732.1 - 0.021 15.3 0.1 0.075 13.5 0.1 2.0 1 0 0 1 1 1 0 CoA binding domain Rad60-SLD PF11976.8 EPS25734.1 - 4.9e-20 71.1 0.3 5.8e-20 70.9 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EPS25734.1 - 5.6e-11 42.0 0.1 6.4e-11 41.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family MTCP1 PF08991.10 EPS25735.1 - 4.3e-29 100.5 10.4 5.2e-29 100.3 10.4 1.1 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 EPS25735.1 - 0.0042 17.2 7.0 0.0042 17.2 7.0 1.6 2 0 0 2 2 2 1 CHCH domain Cmc1 PF08583.10 EPS25735.1 - 0.45 10.6 7.2 0.3 11.2 4.2 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Nup84_Nup100 PF04121.13 EPS25736.1 - 2.6e-175 584.6 1.5 3.8e-175 584.0 1.5 1.2 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 DUF1351 PF07083.11 EPS25736.1 - 0.035 13.9 3.7 0.036 13.8 1.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1351) KicB PF03882.14 EPS25736.1 - 0.09 13.0 0.4 0.27 11.5 0.4 1.9 1 0 0 1 1 1 0 MukF winged-helix domain DUF3510 PF12022.8 EPS25736.1 - 0.55 10.6 4.9 1.5 9.2 4.9 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) Cation_ATPase_C PF00689.21 EPS25737.1 - 7.6e-45 152.9 8.8 7.6e-45 152.9 8.8 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EPS25737.1 - 2.9e-38 131.2 0.9 2.9e-38 131.2 0.9 2.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 EPS25737.1 - 1.5e-22 79.4 0.0 2.9e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EPS25737.1 - 1.9e-19 70.8 0.1 7.1e-19 68.9 0.0 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EPS25737.1 - 1.6e-10 40.5 0.7 8.3e-09 35.0 0.0 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EPS25737.1 - 4.7e-05 23.3 1.7 0.00033 20.5 2.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase LptF_LptG PF03739.14 EPS25737.1 - 0.0039 16.1 1.3 0.13 11.0 3.2 2.2 2 0 0 2 2 2 1 Lipopolysaccharide export system permease LptF/LptG RskA PF10099.9 EPS25737.1 - 0.0089 16.3 0.1 9.5 6.5 0.0 3.4 2 1 0 2 2 2 2 Anti-sigma-K factor rskA DUF4870 PF09685.10 EPS25737.1 - 0.11 12.7 0.1 0.11 12.7 0.1 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4870) D-ser_dehydrat PF14031.6 EPS25738.1 - 3.8e-24 85.2 0.2 8e-24 84.1 0.2 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 EPS25738.1 - 1.1e-12 48.1 0.0 1.7e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Transp_cyt_pur PF02133.15 EPS25739.1 - 3.1e-17 62.5 31.4 4.6e-17 61.9 31.4 1.3 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2236 PF09995.9 EPS25740.1 - 1.8e-08 34.9 0.2 3.6e-08 33.9 0.2 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) AGT PF11440.8 EPS25740.1 - 0.15 11.1 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 DNA alpha-glucosyltransferase Tubulin PF00091.25 EPS25741.1 - 1e-67 228.2 0.0 2.1e-67 227.1 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EPS25741.1 - 1e-43 148.5 0.0 1.8e-43 147.7 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EPS25741.1 - 5.1e-05 23.6 0.0 0.00014 22.1 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 EPS25741.1 - 0.002 17.4 0.0 0.02 14.1 0.0 2.1 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 EPS25741.1 - 0.0029 17.3 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain RRM_1 PF00076.22 EPS25742.1 - 5.6e-16 58.1 0.0 2.6e-06 27.1 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EPS25742.1 - 0.0023 18.0 0.0 0.0064 16.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif ABC_tran_Xtn PF12848.7 EPS25742.1 - 1 9.5 3.9 9.5 6.3 1.2 2.5 2 0 0 2 2 2 0 ABC transporter Ammonium_transp PF00909.21 EPS25743.1 - 3e-121 404.9 30.8 3.4e-121 404.7 30.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Pkinase PF00069.25 EPS25744.1 - 4e-65 219.8 0.0 7e-65 219.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS25744.1 - 1.2e-35 123.1 0.0 3.5e-25 88.8 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EPS25744.1 - 3e-05 23.0 0.0 5.5e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EPS25744.1 - 6.1e-05 22.5 0.1 0.0042 16.4 0.0 2.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EPS25744.1 - 0.0018 18.3 0.0 0.0045 16.9 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EPS25744.1 - 0.022 13.8 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 FtsX_ECD PF18075.1 EPS25744.1 - 0.043 14.4 0.1 0.23 12.1 0.0 2.3 2 0 0 2 2 2 0 FtsX extracellular domain Vac_ImportDeg PF09783.9 EPS25745.1 - 3.6e-68 228.4 2.6 4.4e-68 228.2 2.6 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Mago_nashi PF02792.14 EPS25746.1 - 8.3e-74 246.4 0.3 9.3e-74 246.2 0.3 1.0 1 0 0 1 1 1 1 Mago nashi protein Adaptin_N PF01602.20 EPS25747.1 - 1.5e-90 304.2 10.7 2.7e-90 303.4 10.7 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 EPS25747.1 - 1.4e-58 196.8 0.7 3e-58 195.7 0.7 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 EPS25747.1 - 1.6e-56 189.7 0.0 5e-56 188.2 0.0 1.9 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 EPS25747.1 - 1.7e-14 54.2 6.0 3.5e-10 40.1 0.0 3.4 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EPS25747.1 - 8.5e-08 32.5 10.0 0.00041 20.7 0.0 5.2 4 2 1 5 5 5 2 HEAT repeats Coatomer_g_Cpla PF16381.5 EPS25747.1 - 3e-05 24.1 0.0 0.00023 21.3 0.0 2.4 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT PF02985.22 EPS25747.1 - 0.00054 20.0 0.6 2.5 8.6 0.1 4.3 3 0 0 3 3 3 1 HEAT repeat AP4E_app_platf PF14807.6 EPS25747.1 - 0.0058 17.0 0.3 0.022 15.1 0.3 2.1 1 0 0 1 1 1 1 Adaptin AP4 complex epsilon appendage platform HEAT_EZ PF13513.6 EPS25747.1 - 0.032 14.7 2.8 1.4 9.5 0.1 4.4 5 0 0 5 5 5 0 HEAT-like repeat DUF5578 PF17741.1 EPS25747.1 - 0.089 12.2 6.5 1.4 8.3 0.1 4.0 2 1 1 4 4 4 0 Family of unknown function (DUF5578) Arm PF00514.23 EPS25747.1 - 0.77 9.9 5.5 5.2 7.3 0.1 4.7 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat DAGK_cat PF00781.24 EPS25748.1 - 7e-24 83.8 0.0 1.2e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Nop52 PF05997.12 EPS25749.1 - 5.9e-51 173.3 0.0 2.4e-50 171.4 0.0 1.8 1 1 0 1 1 1 1 Nucleolar protein,Nop52 NOT2_3_5 PF04153.18 EPS25749.1 - 0.064 13.3 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 NOT2 / NOT3 / NOT5 family ABC2_membrane PF01061.24 EPS25750.1 - 3.1e-74 248.9 43.5 8.2e-42 143.0 22.4 3.2 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 EPS25750.1 - 3.8e-37 127.8 0.0 2e-18 67.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EPS25750.1 - 1.1e-33 115.0 4.8 7.9e-32 109.0 0.2 3.3 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.6 EPS25750.1 - 4.7e-16 59.2 0.0 1.1e-15 58.0 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 EPS25750.1 - 1.8e-08 34.9 0.5 0.0061 17.0 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain ABC2_membrane_3 PF12698.7 EPS25750.1 - 2.4e-06 26.9 36.2 3.3e-05 23.2 11.8 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 EPS25750.1 - 1.3e-05 25.2 0.1 0.0065 16.4 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 EPS25750.1 - 1.5e-05 24.7 0.1 0.0033 17.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EPS25750.1 - 5e-05 23.8 0.0 0.0042 17.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EPS25750.1 - 0.00057 20.1 0.1 0.084 13.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EPS25750.1 - 0.00084 19.1 0.1 0.35 10.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EPS25750.1 - 0.0018 18.0 2.9 0.056 13.2 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.6 EPS25750.1 - 0.0021 18.5 0.6 0.18 12.2 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EPS25750.1 - 0.0047 17.2 0.3 2 8.7 0.1 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EPS25750.1 - 0.014 15.5 0.3 5.2 7.2 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase SMC_N PF02463.19 EPS25750.1 - 0.023 14.2 0.1 0.24 10.8 0.0 2.5 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain cobW PF02492.19 EPS25750.1 - 0.026 14.1 2.5 0.18 11.3 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.6 EPS25750.1 - 0.052 13.4 0.1 2 8.2 0.0 2.6 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system Ploopntkinase3 PF18751.1 EPS25750.1 - 0.09 12.7 0.1 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Rad17 PF03215.15 EPS25750.1 - 0.13 12.2 0.0 7.4 6.5 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain NACHT PF05729.12 EPS25750.1 - 0.27 11.1 4.9 4.4 7.2 0.3 2.7 3 0 0 3 3 2 0 NACHT domain UBD PF16455.5 EPS25751.1 - 5.2e-42 142.3 0.0 8.5e-42 141.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-binding domain ubiquitin PF00240.23 EPS25751.1 - 0.047 13.4 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family DUF1604 PF07713.13 EPS25752.1 - 4.5e-42 141.8 5.9 3.9e-41 138.8 1.9 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF1604) G-patch PF01585.23 EPS25752.1 - 3.2e-07 30.1 0.7 8.5e-07 28.8 0.7 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EPS25752.1 - 0.0054 16.8 4.2 0.022 14.9 0.3 3.0 2 1 0 2 2 2 1 G-patch domain Glyco_transf_90 PF05686.12 EPS25753.1 - 8.1e-16 57.9 4.3 5.5e-10 38.7 0.9 3.9 2 1 0 2 2 2 2 Glycosyl transferase family 90 TPR_10 PF13374.6 EPS25753.1 - 0.047 13.6 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Sugar_tr PF00083.24 EPS25755.1 - 7.6e-96 321.7 22.2 8.9e-96 321.5 22.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS25755.1 - 3.7e-26 91.9 17.6 3.7e-26 91.9 17.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Pox_A14 PF05767.12 EPS25755.1 - 0.0078 16.3 0.1 0.04 14.1 0.1 2.3 1 0 0 1 1 1 1 Poxvirus virion envelope protein A14 Ank_5 PF13857.6 EPS25756.1 - 4.6e-10 39.6 4.0 8.3e-07 29.2 1.5 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) TIG PF01833.24 EPS25756.1 - 5.4e-10 39.2 0.1 2.5e-09 37.1 0.1 2.1 1 0 0 1 1 1 1 IPT/TIG domain Ank_2 PF12796.7 EPS25756.1 - 2.2e-07 31.3 0.1 7.3e-07 29.7 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EPS25756.1 - 5.4e-07 29.8 6.0 0.0064 16.9 0.1 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EPS25756.1 - 1.6e-06 28.5 0.9 1e-05 26.0 0.4 2.6 1 1 2 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPS25756.1 - 6e-05 23.1 1.2 0.82 10.4 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EPS25757.1 - 3.7e-13 49.9 0.0 1.1e-05 25.9 0.0 2.4 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EPS25757.1 - 3e-10 39.4 0.0 0.0019 18.6 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 EPS25757.1 - 7.6e-09 35.9 0.1 0.076 13.6 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EPS25757.1 - 1.4e-08 34.8 0.1 1.7e-06 28.2 0.0 2.9 2 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 EPS25757.1 - 1.5e-07 31.5 0.0 0.026 15.0 0.1 4.4 4 1 0 4 4 4 1 Ankyrin repeat NYN PF01936.18 EPS25758.1 - 4.1e-32 111.7 0.0 6e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 NYN domain OST-HTH PF12872.7 EPS25758.1 - 5.4e-16 58.2 0.0 1.1e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 OST-HTH/LOTUS domain PIN7 PF18475.1 EPS25758.1 - 0.061 13.9 0.0 0.12 13.0 0.0 1.5 1 0 0 1 1 1 0 PIN domain Phage_rep_O PF04492.13 EPS25758.1 - 0.2 12.3 0.0 0.81 10.3 0.0 2.1 2 0 0 2 2 2 0 Bacteriophage replication protein O DUF2065 PF09838.9 EPS25760.1 - 0.074 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2065) DUF3829 PF12889.7 EPS25760.1 - 0.21 11.0 0.1 0.41 10.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) Glyco_hydro_61 PF03443.14 EPS25762.1 - 5.8e-72 241.9 0.1 1.1e-71 241.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 SOG2 PF10428.9 EPS25762.1 - 0.41 9.8 20.5 0.47 9.6 20.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Tmemb_cc2 PF10267.9 EPS25762.1 - 7.1 5.7 7.2 9.4 5.3 7.2 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein SPX PF03105.19 EPS25762.1 - 7.9 6.3 22.6 11 5.8 22.6 1.1 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 EPS25762.1 - 8.8 5.1 15.8 12 4.6 15.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain SUI1 PF01253.22 EPS25763.1 - 5.9e-20 71.6 0.4 1.2e-19 70.6 0.4 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 EPS25763.1 - 1.5e-10 41.6 0.4 1.6e-09 38.3 0.0 2.9 2 1 0 2 2 2 1 Pre-PUA-like domain Kin17_mid PF10357.9 EPS25763.1 - 0.093 12.6 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of Kin17 curved DNA-binding protein SWIB PF02201.18 EPS25763.1 - 0.14 12.1 0.0 0.72 9.8 0.0 2.2 2 0 0 2 2 2 0 SWIB/MDM2 domain Dabb PF07876.12 EPS25764.1 - 7.4e-17 61.8 0.0 8.4e-17 61.6 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain La PF05383.17 EPS25765.1 - 2.7e-21 75.4 0.0 4.6e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 EPS25765.1 - 2.9e-08 33.4 0.1 7.6e-08 32.1 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) IHABP4_N PF16174.5 EPS25765.1 - 2.5 8.7 23.1 0.56 10.8 3.3 2.6 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal Chitin_synth_2 PF03142.15 EPS25766.1 - 6.6e-21 74.5 2.4 6.6e-21 74.5 2.4 2.5 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EPS25766.1 - 3.4e-16 59.7 1.8 3.4e-16 59.7 1.8 2.6 2 2 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EPS25766.1 - 2.4e-10 40.7 0.0 7.1e-10 39.2 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EPS25766.1 - 0.0065 16.3 0.1 4 7.2 0.1 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 DUF4481 PF14800.6 EPS25766.1 - 1.6 8.1 7.5 2.7 7.4 7.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) HSP70 PF00012.20 EPS25767.1 - 1e-166 555.7 1.1 1e-166 555.7 1.1 2.0 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 EPS25767.1 - 3.8e-10 39.1 0.0 1.5e-09 37.2 0.0 1.8 2 0 0 2 2 2 1 MreB/Mbl protein Rad52_Rad22 PF04098.15 EPS25767.1 - 0.0029 17.6 1.9 3 7.8 2.2 2.5 2 0 0 2 2 2 2 Rad52/22 family double-strand break repair protein FtsA PF14450.6 EPS25767.1 - 0.0029 18.0 0.2 4.7 7.7 0.0 3.0 2 1 0 2 2 2 2 Cell division protein FtsA DUF2746 PF10874.8 EPS25767.1 - 0.12 12.8 0.0 0.42 11.1 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) DUF4140 PF13600.6 EPS25767.1 - 6.7 7.2 8.4 37 4.8 0.2 3.0 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) LicD PF04991.13 EPS25768.1 - 4.8e-23 82.5 4.9 5.8e-17 62.6 2.0 2.1 1 1 1 2 2 2 2 LicD family WLM PF08325.10 EPS25769.1 - 6.9e-52 176.3 0.2 2e-51 174.8 0.0 1.7 2 0 0 2 2 2 1 WLM domain SprT-like PF10263.9 EPS25769.1 - 0.001 18.9 0.1 0.0018 18.1 0.1 1.4 1 0 0 1 1 1 1 SprT-like family DUF45 PF01863.17 EPS25769.1 - 0.0029 17.7 0.1 0.0067 16.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 ubiquitin PF00240.23 EPS25769.1 - 0.076 12.8 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin family Thiolase_N PF00108.23 EPS25770.1 - 2.8e-68 230.1 0.1 4.6e-68 229.4 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EPS25770.1 - 2.6e-41 140.1 2.6 2.7e-41 140.0 0.4 2.0 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EPS25770.1 - 0.0027 17.3 0.7 0.009 15.6 0.3 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 EPS25770.1 - 0.11 12.7 0.0 0.33 11.1 0.0 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Stathmin PF00836.19 EPS25771.1 - 0.15 12.1 0.9 0.32 10.9 0.9 1.5 1 0 0 1 1 1 0 Stathmin family DASH_Ask1 PF08655.10 EPS25772.1 - 1.3e-29 101.9 0.1 2.3e-29 101.1 0.1 1.4 1 0 0 1 1 1 1 DASH complex subunit Ask1 FAD_binding_3 PF01494.19 EPS25773.1 - 2.2e-20 73.2 0.1 3.1e-12 46.4 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 EPS25773.1 - 0.00023 21.3 0.0 0.0011 19.1 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HIG_1_N PF04588.13 EPS25774.1 - 1.6e-07 31.4 0.4 3.4e-07 30.4 0.4 1.6 1 0 0 1 1 1 1 Hypoxia induced protein conserved region KBP_C PF12309.8 EPS25774.1 - 0.076 12.5 7.4 0.13 11.7 7.4 1.3 1 0 0 1 1 1 0 KIF-1 binding protein C terminal Presenilin PF01080.17 EPS25774.1 - 1.3 7.7 5.1 1.8 7.3 5.1 1.4 1 0 0 1 1 1 0 Presenilin Med26 PF08711.11 EPS25775.1 - 5.3e-10 39.2 0.2 1e-09 38.2 0.2 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Tom5 PF10642.9 EPS25776.1 - 5.2e-21 74.4 0.1 5.6e-21 74.3 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Pombe_5TM PF09437.10 EPS25776.1 - 0.15 11.7 0.0 0.16 11.6 0.0 1.0 1 0 0 1 1 1 0 Pombe specific 5TM protein Nup54 PF13874.6 EPS25777.1 - 3.7e-38 130.8 0.1 3.7e-38 130.8 0.1 2.0 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nup54_57_C PF18570.1 EPS25777.1 - 2e-11 43.2 4.8 4e-11 42.3 4.8 1.5 1 0 0 1 1 1 1 NUP57/Nup54 C-terminal domain Nucleoporin_FG PF13634.6 EPS25777.1 - 2.5e-11 44.3 67.5 7.5e-08 33.1 32.7 3.0 1 1 2 3 3 3 2 Nucleoporin FG repeat region Spc29 PF17082.5 EPS25777.1 - 0.038 13.8 0.5 5.7 6.7 0.9 2.3 1 1 1 2 2 2 0 Spindle Pole Component 29 CX9C PF16860.5 EPS25778.1 - 0.0007 19.6 7.5 0.00085 19.3 1.7 2.3 2 0 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 EPS25778.1 - 0.0012 19.0 3.4 0.0012 19.0 3.4 2.6 3 0 0 3 3 3 2 CHCH domain DNA_circ_N PF07157.12 EPS25778.1 - 0.084 13.3 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 DNA circularisation protein N-terminus Pet191_N PF10203.9 EPS25778.1 - 0.24 11.7 10.6 1.5 9.1 1.3 3.0 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 EPS25778.1 - 0.4 10.7 13.4 0.49 10.4 3.2 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX6B PF02297.17 EPS25778.1 - 6.9 7.0 10.1 6.3e+02 0.7 10.1 2.2 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb ACBP PF00887.19 EPS25779.1 - 1.3e-20 73.3 0.0 2.7e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein PI3K_1B_p101 PF10486.9 EPS25779.1 - 1.1 7.0 4.0 1.5 6.5 4.0 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Macoilin PF09726.9 EPS25779.1 - 2.4 6.6 4.9 3.4 6.1 4.9 1.2 1 0 0 1 1 1 0 Macoilin family FAM176 PF14851.6 EPS25779.1 - 3.1 7.4 5.3 7.1 6.3 5.3 1.6 1 0 0 1 1 1 0 FAM176 family AA_permease_2 PF13520.6 EPS25780.1 - 2.6e-60 204.5 54.0 3.2e-60 204.2 54.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPS25780.1 - 7.2e-31 107.3 50.1 9.9e-31 106.8 50.1 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4239 PF14023.6 EPS25780.1 - 0.12 12.0 1.9 2.1 8.0 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) DUF3493 PF11998.8 EPS25780.1 - 0.14 12.4 1.1 0.42 10.8 0.0 2.4 2 0 0 2 2 2 0 Low psii accumulation1 / Rep27 JmjC PF02373.22 EPS25781.1 - 1.5e-37 128.5 1.5 1.9e-37 128.1 0.5 1.8 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.6 EPS25781.1 - 4.9e-18 65.3 3.2 8.5e-18 64.5 3.2 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EPS25781.1 - 8.7e-18 64.4 3.1 1.9e-17 63.3 3.1 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain JmjN PF02375.17 EPS25781.1 - 1.9e-14 53.3 0.4 4.1e-14 52.2 0.4 1.6 1 0 0 1 1 1 1 jmjN domain zf-TFIIIC PF12660.7 EPS25781.1 - 0.51 10.3 4.1 0.32 11.0 1.8 1.8 2 0 0 2 2 2 0 Putative zinc-finger of transcription factor IIIC complex 4HBT_2 PF13279.6 EPS25782.1 - 3.2e-10 40.6 0.0 5.2e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Cyclase PF04199.13 EPS25784.1 - 9.3e-12 45.4 0.1 1.1e-10 41.9 0.0 2.0 1 1 1 2 2 2 1 Putative cyclase DUF5490 PF17593.2 EPS25784.1 - 0.056 13.5 0.2 0.28 11.2 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5490) RHD3 PF05879.12 EPS25785.1 - 0 1070.0 0.0 0 1069.7 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.19 EPS25785.1 - 2.8e-06 26.8 0.4 4.7e-06 26.1 0.4 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.23 EPS25785.1 - 3.4e-06 27.2 0.0 6.5e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EPS25785.1 - 0.00021 21.4 0.0 0.00041 20.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 EPS25785.1 - 0.00038 20.7 0.0 0.00092 19.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain Septin PF00735.18 EPS25785.1 - 0.018 14.3 0.1 0.036 13.3 0.1 1.5 1 0 0 1 1 1 0 Septin Zn_clus PF00172.18 EPS25786.1 - 0.0088 16.1 7.2 0.017 15.2 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GTP_EFTU PF00009.27 EPS25787.1 - 2.6e-57 193.5 0.1 3.6e-57 193.1 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EPS25787.1 - 1e-20 74.1 0.0 2.2e-20 73.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EPS25787.1 - 4.7e-17 62.1 2.6 6.2e-17 61.8 1.3 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EPS25787.1 - 1.1e-05 25.5 0.1 2.5e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EPS25787.1 - 0.0015 18.5 0.3 0.0088 16.0 0.0 2.0 1 1 1 2 2 2 1 RsgA GTPase cobW PF02492.19 EPS25787.1 - 0.017 14.7 0.3 0.17 11.4 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 EPS25787.1 - 0.038 13.7 0.1 6.1 6.6 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation IF3_C PF00707.22 EPS25788.1 - 1.2e-09 38.0 2.1 2.1e-09 37.2 2.1 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 EPS25788.1 - 1.9e-07 31.2 0.0 5.1e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain mIF3 PF14877.6 EPS25788.1 - 4.3e-06 26.5 5.6 1.9e-05 24.4 5.6 1.9 1 1 1 2 2 2 1 Mitochondrial translation initiation factor LppA PF16708.5 EPS25788.1 - 0.0036 17.3 0.4 0.0056 16.6 0.4 1.3 1 0 0 1 1 1 1 Lipoprotein confined to pathogenic Mycobacterium Syntaxin-18_N PF10496.9 EPS25788.1 - 0.092 13.0 1.0 0.18 12.1 1.0 1.5 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus GDA1_CD39 PF01150.17 EPS25789.1 - 7.5e-101 337.8 0.0 1e-100 337.4 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family SR-25 PF10500.9 EPS25790.1 - 0.0023 17.6 21.0 0.0031 17.1 21.0 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein RNA_polI_A34 PF08208.11 EPS25790.1 - 0.0033 17.5 16.6 0.0045 17.1 16.6 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 AP3D1 PF06375.11 EPS25790.1 - 0.0034 17.6 17.3 0.005 17.1 17.3 1.2 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 Peptidase_S49_N PF08496.10 EPS25790.1 - 0.0081 16.2 11.7 0.011 15.8 11.7 1.2 1 0 0 1 1 1 1 Peptidase family S49 N-terminal Ferlin_C PF16165.5 EPS25790.1 - 0.021 14.8 9.9 0.033 14.1 9.9 1.3 1 0 0 1 1 1 0 Ferlin C-terminus Rtf2 PF04641.12 EPS25790.1 - 0.12 11.7 13.2 0.18 11.2 13.2 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Agouti PF05039.12 EPS25790.1 - 0.18 12.6 6.3 0.3 11.8 6.3 1.4 1 0 0 1 1 1 0 Agouti protein Eapp_C PF10238.9 EPS25790.1 - 0.26 11.3 4.8 0.41 10.7 4.8 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein DUF3464 PF11947.8 EPS25790.1 - 0.29 10.9 9.5 0.46 10.2 9.5 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 EIIBC-GUT_N PF03612.14 EPS25790.1 - 0.31 10.8 5.2 0.44 10.3 5.2 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus BSMAP PF12280.8 EPS25790.1 - 0.31 11.2 3.2 0.43 10.8 3.2 1.2 1 0 0 1 1 1 0 Brain specific membrane anchored protein LYRIC PF15686.5 EPS25790.1 - 0.35 10.4 16.4 0.44 10.0 16.4 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family Med19 PF10278.9 EPS25790.1 - 0.35 10.8 21.6 0.56 10.1 21.6 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Connexin PF00029.19 EPS25790.1 - 0.46 10.2 4.8 0.68 9.7 4.8 1.2 1 0 0 1 1 1 0 Connexin GAGA_bind PF06217.12 EPS25790.1 - 0.51 10.6 11.5 0.66 10.2 11.5 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family POX PF07526.11 EPS25790.1 - 0.51 10.9 7.5 8.1 7.0 6.4 2.1 2 0 0 2 2 2 0 Associated with HOX HA2 PF04408.23 EPS25790.1 - 0.61 10.4 4.0 0.97 9.7 4.0 1.3 1 0 0 1 1 1 0 Helicase associated domain (HA2) YqfQ PF14181.6 EPS25790.1 - 1 9.5 9.1 1.5 9.0 9.1 1.2 1 0 0 1 1 1 0 YqfQ-like protein Sec62 PF03839.16 EPS25790.1 - 1.4 8.4 11.4 2.1 7.8 11.4 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 FAM199X PF15814.5 EPS25790.1 - 3.2 6.7 9.0 4.3 6.3 9.0 1.1 1 0 0 1 1 1 0 Protein family FAM199X Presenilin PF01080.17 EPS25790.1 - 5.1 5.8 4.7 5.9 5.6 4.7 1.1 1 0 0 1 1 1 0 Presenilin Coilin_N PF15862.5 EPS25790.1 - 5.8 6.7 19.8 4.8 7.0 18.1 1.7 2 0 0 2 2 2 0 Coilin N-terminus Pectate_lyase_3 PF12708.7 EPS25791.1 - 5.5e-50 170.2 22.0 1.9e-43 148.8 5.8 3.7 2 2 2 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EPS25791.1 - 0.017 14.8 3.5 0.53 10.0 0.0 3.2 3 0 0 3 3 3 0 N terminal extension of bacteriophage endosialidase DUF4598 PF15370.6 EPS25792.1 - 1.8e-34 118.5 4.2 1.8e-34 118.5 4.2 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4598) BUD22 PF09073.10 EPS25792.1 - 0.16 11.3 19.4 0.21 10.9 19.4 1.1 1 0 0 1 1 1 0 BUD22 DUF913 PF06025.12 EPS25792.1 - 0.68 8.8 5.7 0.12 11.4 2.2 1.5 1 1 1 2 2 2 0 Domain of Unknown Function (DUF913) FAM176 PF14851.6 EPS25792.1 - 4.8 6.8 12.4 3.4 7.3 6.5 2.2 2 0 0 2 2 2 0 FAM176 family CCDC106 PF15794.5 EPS25792.1 - 6 6.5 6.9 0.55 9.9 2.1 1.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 COMPASS-Shg1 PF05205.12 EPS25793.1 - 8.3e-28 97.1 1.4 2.1e-27 95.8 0.2 2.3 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 MAJIN PF15077.6 EPS25793.1 - 3.9 7.2 10.8 9.2 6.0 10.8 1.7 1 0 0 1 1 1 0 Membrane-anchored junction protein Cation_efflux PF01545.21 EPS25795.1 - 3e-13 49.9 10.1 4e-13 49.6 10.1 1.1 1 0 0 1 1 1 1 Cation efflux family zf-rbx1 PF12678.7 EPS25796.1 - 2.4e-08 34.2 3.0 6.6e-08 32.7 3.0 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EPS25796.1 - 5.4e-08 33.0 2.1 5.4e-08 33.0 2.1 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EPS25796.1 - 8.2e-07 28.8 1.2 1.5e-06 28.0 1.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EPS25796.1 - 2.4e-06 27.4 2.2 4.1e-06 26.7 1.3 2.0 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EPS25796.1 - 2.6e-06 27.1 6.8 5.4e-06 26.2 2.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EPS25796.1 - 0.00012 21.6 1.5 0.00084 18.9 0.7 2.4 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 EPS25796.1 - 0.00017 21.4 1.0 0.00017 21.4 1.0 1.9 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EPS25796.1 - 0.00032 20.5 1.8 0.00032 20.5 1.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EPS25796.1 - 0.00053 19.7 11.5 0.007 16.1 0.2 4.1 4 0 0 4 4 4 2 RING-like zinc finger zf-RING_UBOX PF13445.6 EPS25796.1 - 0.00061 19.8 5.5 0.0013 18.7 1.5 3.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EPS25796.1 - 0.0077 16.3 1.6 0.022 14.8 1.6 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2921 PF11145.8 EPS25796.1 - 0.012 13.5 0.3 0.018 12.9 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) zf-C3H2C3 PF17122.5 EPS25796.1 - 0.67 10.0 3.1 2.2 8.4 1.6 2.4 2 0 0 2 2 2 0 Zinc-finger FANCL_C PF11793.8 EPS25796.1 - 6.4 7.0 6.4 29 4.9 6.4 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain GCV_H PF01597.19 EPS25797.1 - 1.4e-35 121.9 0.9 1.6e-35 121.6 0.9 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Ribosomal_S6 PF01250.17 EPS25798.1 - 6.3e-21 74.5 0.0 8e-21 74.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 Hydrolase_4 PF12146.8 EPS25799.1 - 0.00014 21.2 0.0 0.00024 20.4 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EPS25799.1 - 0.00023 21.8 3.1 0.00053 20.7 3.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 EPS25799.1 - 0.0003 20.4 0.0 0.0005 19.6 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 EPS25799.1 - 0.0015 18.3 0.0 0.0027 17.5 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.13 EPS25799.1 - 0.021 14.7 0.0 0.034 14.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold LCAT PF02450.15 EPS25799.1 - 0.022 13.9 0.0 0.034 13.3 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Chs7 PF12271.8 EPS25800.1 - 1.6e-125 418.3 17.3 1.8e-125 418.1 17.3 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone UPF0242 PF06785.11 EPS25800.1 - 3.9 7.5 4.5 16 5.5 4.5 2.0 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4796 PF16044.5 EPS25801.1 - 0.13 11.9 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) Acetyltransf_10 PF13673.7 EPS25805.1 - 3.6e-11 43.1 0.0 6.2e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EPS25805.1 - 1.4e-09 38.3 0.0 2.1e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPS25805.1 - 9.3e-09 35.5 0.0 1.2e-08 35.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EPS25805.1 - 0.00047 20.1 0.0 0.00081 19.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EPS25805.1 - 0.0009 19.3 0.4 0.22 11.6 0.0 2.7 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EPS25805.1 - 0.00095 19.3 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Arrestin_C PF02752.22 EPS25807.1 - 2.4e-20 73.4 0.0 1.3e-19 71.0 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EPS25807.1 - 1.6e-08 34.7 0.0 0.00025 21.1 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 EPS25807.1 - 0.14 11.9 0.0 0.41 10.3 0.0 1.8 2 0 0 2 2 2 0 Arrestin_N terminal like RRM_1 PF00076.22 EPS25810.1 - 1.9e-61 203.8 0.0 1.7e-21 75.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EPS25810.1 - 5.7e-10 38.9 0.0 0.0018 18.1 0.0 3.6 3 1 0 3 3 3 3 Occluded RNA-recognition motif RRM_5 PF13893.6 EPS25810.1 - 1.6e-08 34.2 0.0 0.00034 20.2 0.0 3.2 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EPS25810.1 - 0.00015 21.6 0.0 0.54 10.3 0.0 3.4 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EPS25810.1 - 0.0002 21.4 0.1 0.3 11.2 0.0 3.2 3 1 0 3 3 3 2 RNA recognition motif RRM_8 PF11835.8 EPS25810.1 - 0.00029 21.0 0.0 0.19 11.9 0.0 2.4 2 0 0 2 2 2 2 RRM-like domain SET_assoc PF11767.8 EPS25810.1 - 0.0036 16.9 0.0 1.8 8.2 0.0 2.4 2 0 0 2 2 2 2 Histone lysine methyltransferase SET associated Cas_Cas2CT1978 PF09707.10 EPS25810.1 - 0.0044 17.1 0.0 3.3 7.8 0.0 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) PHM7_cyt PF14703.6 EPS25810.1 - 0.044 14.0 0.0 16 5.7 0.0 3.2 2 1 0 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter RRM_3 PF08777.11 EPS25810.1 - 0.099 12.7 0.0 2.4 8.2 0.0 2.4 2 0 0 2 2 2 0 RNA binding motif Acetyltransf_10 PF13673.7 EPS25810.1 - 0.18 11.8 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PIG-Y PF15159.6 EPS25811.1 - 3.5e-23 82.3 8.2 5.7e-23 81.6 8.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y DUF1218 PF06749.12 EPS25811.1 - 0.044 14.3 2.3 4.7 7.8 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) GATase_4 PF13230.6 EPS25812.1 - 2.4e-12 46.3 0.0 2.8e-11 42.9 0.0 2.1 1 1 0 2 2 2 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 EPS25812.1 - 8.1e-09 35.8 0.0 1.7e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Dynamin_N PF00350.23 EPS25813.1 - 5.2e-44 150.3 0.0 1.2e-43 149.1 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.20 EPS25813.1 - 1.2e-15 57.5 0.0 1.2e-12 47.7 0.0 2.5 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 EPS25813.1 - 6.7e-05 22.9 0.0 0.00061 19.9 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase Se-cys_synth_N PF12390.8 EPS25813.1 - 0.043 14.1 0.0 0.2 11.9 0.0 2.2 1 0 0 1 1 1 0 Selenocysteine synthase N terminal AAA_16 PF13191.6 EPS25813.1 - 0.059 13.8 0.8 0.21 12.0 0.1 2.2 2 1 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 EPS25813.1 - 0.073 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EPS25813.1 - 0.084 12.6 0.9 0.24 11.1 0.1 2.0 2 0 0 2 2 2 0 AAA ATPase domain SRI PF08236.11 EPS25813.1 - 0.091 12.9 0.3 0.3 11.3 0.3 1.9 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain FtsJ PF01728.19 EPS25814.1 - 4.7e-13 49.6 0.0 7e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_11 PF08241.12 EPS25814.1 - 0.021 15.5 0.1 0.16 12.6 0.1 2.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltr_RsmB-F PF01189.17 EPS25814.1 - 0.2 11.3 0.0 26 4.4 0.0 3.0 3 0 0 3 3 3 0 16S rRNA methyltransferase RsmB/F Pyr_redox_2 PF07992.14 EPS25815.1 - 4.4e-54 183.7 0.0 5.7e-54 183.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPS25815.1 - 3.4e-11 43.5 0.0 9.6e-10 38.9 0.1 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EPS25815.1 - 0.00039 19.8 0.0 0.23 10.6 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase EcoR124_C PF12008.8 EPS25815.1 - 0.042 13.5 0.7 0.23 11.1 0.1 2.0 2 0 0 2 2 2 0 Type I restriction and modification enzyme - subunit R C terminal Glyco_hydro_10 PF00331.20 EPS25816.1 - 1.7e-89 300.1 0.1 2e-89 299.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Sugar_tr PF00083.24 EPS25817.1 - 5.3e-90 302.4 19.4 6.4e-90 302.2 19.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS25817.1 - 6e-25 87.9 17.7 6e-25 87.9 17.7 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Cyclin PF08613.11 EPS25820.1 - 1.2e-15 58.2 0.1 1.9e-15 57.6 0.1 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EPS25820.1 - 0.00036 20.3 0.0 0.00058 19.6 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ribosomal_L27A PF00828.19 EPS25821.1 - 9.5e-31 107.1 0.2 1.3e-30 106.7 0.2 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A HTH_17 PF12728.7 EPS25821.1 - 0.11 12.6 0.3 7.7 6.8 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain Pkinase PF00069.25 EPS25822.1 - 6.1e-46 156.9 0.0 8e-46 156.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS25822.1 - 3e-26 92.3 0.0 1.7e-24 86.5 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EPS25822.1 - 0.059 12.1 0.0 0.14 10.9 0.0 1.6 1 0 0 1 1 1 0 Fungal protein kinase SH3_1 PF00018.28 EPS25823.1 - 9.7e-06 25.1 0.0 1.8e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EPS25823.1 - 0.0036 17.1 0.0 0.0069 16.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_16 PF18348.1 EPS25823.1 - 0.013 15.3 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial dipeptidyl-peptidase Sh3 domain Rick_17kDa_Anti PF05433.15 EPS25824.1 - 4.5e-06 26.4 6.1 9.7e-06 25.4 6.1 1.5 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 EPS25824.1 - 0.0013 18.7 4.5 0.0024 17.8 4.5 1.4 1 0 0 1 1 1 1 Glycine zipper TraT PF05818.12 EPS25824.1 - 0.37 10.4 0.7 0.55 9.9 0.7 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein API5 PF05918.11 EPS25824.1 - 0.58 8.9 1.4 0.63 8.8 1.4 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) SARAF PF06682.12 EPS25824.1 - 5.3 6.6 12.6 31 4.1 12.6 2.0 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis PQ-loop PF04193.14 EPS25825.1 - 4.6e-37 125.6 12.2 4e-18 64.9 5.5 2.4 2 0 0 2 2 2 2 PQ loop repeat DUF3021 PF11457.8 EPS25825.1 - 0.033 14.5 7.0 0.027 14.8 5.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) MtN3_slv PF03083.16 EPS25825.1 - 0.47 10.5 0.1 0.47 10.5 0.1 2.7 3 0 0 3 3 3 0 Sugar efflux transporter for intercellular exchange SKG6 PF08693.10 EPS25827.1 - 0.00012 21.4 0.5 0.00023 20.5 0.5 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.11 EPS25827.1 - 0.0016 18.5 0.4 0.0028 17.8 0.4 1.4 1 0 0 1 1 1 1 Podoplanin Glycophorin_A PF01102.18 EPS25827.1 - 0.0079 16.4 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 Glycophorin A DUF2207 PF09972.9 EPS25827.1 - 0.091 11.5 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Gram_pos_anchor PF00746.21 EPS25827.1 - 0.17 11.8 1.1 0.33 10.9 1.1 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Aminotran_1_2 PF00155.21 EPS25829.1 - 4e-62 210.5 0.0 5e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.20 EPS25829.1 - 0.017 13.9 0.0 0.043 12.6 0.0 1.6 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Beta_elim_lyase PF01212.21 EPS25829.1 - 0.051 12.8 0.0 0.084 12.1 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_5 PF00266.19 EPS25829.1 - 0.059 12.3 0.0 0.085 11.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V AMP-binding PF00501.28 EPS25830.1 - 3.3e-36 124.8 0.0 4.7e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EPS25830.1 - 1.6e-11 43.9 1.2 1.6e-11 43.9 1.2 1.8 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 EPS25830.1 - 0.00014 22.7 0.0 0.00034 21.5 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Peptidase_M16_C PF05193.21 EPS25831.1 - 1e-52 178.8 0.0 3.3e-52 177.2 0.0 1.9 2 1 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EPS25831.1 - 1.2e-41 142.2 0.0 6.5e-40 136.5 0.0 2.2 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) Tom22 PF04281.13 EPS25832.1 - 1.7e-54 183.4 1.6 1.9e-54 183.2 1.6 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 DUF4211 PF13926.6 EPS25833.1 - 1e-40 139.1 0.0 3.2e-40 137.5 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) PIN_12 PF16289.5 EPS25834.1 - 2.1 8.8 9.3 39 4.7 0.0 2.3 1 1 1 2 2 2 0 PIN domain KIAA1430 PF13879.6 EPS25834.1 - 3.6 8.4 8.2 20 6.0 8.2 2.0 1 1 0 1 1 1 0 KIAA1430 homologue Sugar_tr PF00083.24 EPS25835.1 - 3.6e-98 329.4 26.2 4.1e-98 329.2 26.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS25835.1 - 5.8e-30 104.4 30.3 5.1e-22 78.3 9.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EPS25835.1 - 3.9 5.9 31.5 0.005 15.4 4.4 4.0 2 2 3 5 5 5 0 MFS/sugar transport protein TMEM220 PF15071.6 EPS25835.1 - 5.6 7.8 7.2 1.5 9.6 0.3 3.3 4 0 0 4 4 4 0 Transmembrane family 220, helix Bac_export_2 PF01312.19 EPS25835.1 - 7.3 5.7 7.3 0.44 9.7 1.6 1.8 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family FMO-like PF00743.19 EPS25838.1 - 2e-07 29.8 0.0 7.9e-05 21.3 0.0 2.8 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EPS25838.1 - 2e-05 24.0 0.0 6.2e-05 22.4 0.0 1.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EPS25838.1 - 0.0028 17.0 0.0 0.03 13.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF4274 PF14096.6 EPS25838.1 - 0.2 11.6 0.0 0.42 10.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4274) zf-UDP PF14569.6 EPS25839.1 - 0.0082 16.2 1.4 0.014 15.5 1.4 1.3 1 0 0 1 1 1 1 Zinc-binding RING-finger Prok-RING_4 PF14447.6 EPS25839.1 - 0.077 12.9 4.0 0.18 11.7 4.0 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 SPX PF03105.19 EPS25839.1 - 0.096 12.6 4.0 0.13 12.1 0.8 2.0 2 0 0 2 2 2 0 SPX domain zf-C3HC4 PF00097.25 EPS25839.1 - 0.48 10.3 7.7 3.2 7.7 7.7 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EPS25839.1 - 0.77 10.0 6.6 0.33 11.2 2.5 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF3915 PF13054.6 EPS25839.1 - 0.82 9.7 4.5 1.6 8.7 4.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) zf-RING_5 PF14634.6 EPS25839.1 - 1.5 8.9 9.0 12 6.0 9.1 2.4 1 1 1 2 2 2 0 zinc-RING finger domain FYVE_2 PF02318.16 EPS25839.1 - 1.9 8.7 6.2 0.2 11.9 0.5 2.0 2 0 0 2 2 2 0 FYVE-type zinc finger zf-C3HC4_3 PF13920.6 EPS25839.1 - 5.9 6.8 8.9 19 5.2 8.9 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF3405 PF11885.8 EPS25840.1 - 1.8e-228 759.4 0.0 2.2e-228 759.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Arf PF00025.21 EPS25841.1 - 5.6e-79 263.6 0.1 6.5e-79 263.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EPS25841.1 - 6.2e-15 55.1 0.0 7.7e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EPS25841.1 - 3.1e-14 53.2 0.0 4.3e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EPS25841.1 - 3.1e-13 49.6 1.1 2e-09 37.1 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EPS25841.1 - 4.2e-13 49.2 0.0 4.7e-13 49.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EPS25841.1 - 2.2e-10 40.3 0.0 2.6e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EPS25841.1 - 4.3e-06 26.8 0.0 6.4e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EPS25841.1 - 0.012 15.0 0.4 0.025 13.9 0.4 1.7 1 1 0 1 1 1 0 6-phosphofructo-2-kinase CorA PF01544.18 EPS25842.1 - 1.1e-05 24.9 3.6 0.0071 15.7 0.5 3.2 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein Bee_toxin PF17454.2 EPS25842.1 - 0.16 12.0 0.1 0.31 11.1 0.1 1.4 1 0 0 1 1 1 0 Honey bee toxin Acetyltransf_7 PF13508.7 EPS25843.1 - 1.4e-10 41.4 0.0 2.3e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPS25843.1 - 1.5e-09 38.1 0.0 2.4e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EPS25843.1 - 6.3e-07 29.4 0.1 1.3e-06 28.4 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPS25843.1 - 8.6e-07 28.8 0.2 2.1e-06 27.6 0.2 1.6 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 EPS25843.1 - 0.00098 19.8 0.0 0.0016 19.1 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EPS25843.1 - 0.031 14.3 0.2 0.097 12.7 0.2 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EPS25843.1 - 0.19 11.4 0.1 0.29 10.8 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_L1 PF00687.21 EPS25844.1 - 1.8e-46 158.5 0.2 2e-46 158.3 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family SNF PF00209.18 EPS25844.1 - 0.014 14.1 0.1 0.021 13.6 0.1 1.1 1 0 0 1 1 1 0 Sodium:neurotransmitter symporter family DUF3671 PF12420.8 EPS25844.1 - 0.17 11.9 1.4 0.39 10.8 1.5 1.6 1 1 0 1 1 1 0 Protein of unknown function RhoGEF PF00621.20 EPS25846.1 - 2.9e-36 125.4 0.0 6e-36 124.4 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain Telomerase_RBD PF12009.8 EPS25847.1 - 3.1e-45 153.6 0.3 8.7e-45 152.1 0.2 1.9 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 EPS25847.1 - 4.9e-14 52.4 0.0 3.4e-09 36.6 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) CDK5_activator PF03261.15 EPS25848.1 - 0.9 9.0 6.4 1.1 8.8 6.4 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein RabGAP-TBC PF00566.18 EPS25849.1 - 6.6e-26 91.3 0.0 1.1e-25 90.6 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain SBE2 PF17076.5 EPS25849.1 - 1.7e-06 26.6 3.5 1.7e-06 26.6 3.5 1.4 1 1 0 1 1 1 1 SBE2, cell-wall formation Pkinase PF00069.25 EPS25850.1 - 1.8e-22 80.0 0.0 2.4e-19 69.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EPS25850.1 - 1.6e-15 57.1 0.0 2.7e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ADH_N_2 PF16884.5 EPS25851.1 - 6.7e-26 90.3 0.0 1.3e-25 89.3 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 EPS25851.1 - 7.6e-23 80.9 0.1 1.4e-22 80.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPS25851.1 - 1.9e-09 38.7 0.0 3.6e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AMP-binding PF00501.28 EPS25853.1 - 1.6e-72 244.4 0.0 2.2e-72 244.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EPS25853.1 - 8.7e-28 97.2 0.0 5.6e-27 94.5 0.0 1.9 2 0 0 2 2 2 1 Condensation domain PP-binding PF00550.25 EPS25853.1 - 4e-09 36.7 0.0 1.1e-08 35.3 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EPS25853.1 - 0.00027 21.8 0.0 0.0034 18.3 0.0 2.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Methyltransf_25 PF13649.6 EPS25854.1 - 9.2e-10 39.1 0.0 1.8e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPS25854.1 - 1.9e-08 35.0 0.0 3.3e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPS25854.1 - 9.2e-08 32.1 0.0 2.8e-07 30.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPS25854.1 - 1.6e-07 31.3 0.0 2.4e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS25854.1 - 1.6e-06 28.7 0.0 4e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPS25854.1 - 0.0013 18.1 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CheR PF01739.18 EPS25854.1 - 0.026 14.0 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_32 PF13679.6 EPS25854.1 - 0.16 11.9 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Aminotran_5 PF00266.19 EPS25855.1 - 3.6e-17 62.4 0.0 6.3e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EPS25855.1 - 0.006 15.2 0.0 0.0092 14.5 0.0 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme PhyH PF05721.13 EPS25856.1 - 1.2e-17 64.9 0.2 1.7e-17 64.4 0.2 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) AMP-binding PF00501.28 EPS25857.1 - 9.6e-76 255.1 0.0 1.3e-75 254.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EPS25857.1 - 8.3e-16 57.7 0.0 3e-15 55.8 0.0 1.7 1 1 0 1 1 1 1 Condensation domain PP-binding PF00550.25 EPS25857.1 - 6.6e-11 42.4 0.1 8.1e-10 38.9 0.1 2.7 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EPS25857.1 - 0.12 13.3 0.0 0.76 10.8 0.0 2.4 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain PhyH PF05721.13 EPS25858.1 - 1.1e-19 71.5 0.0 2e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 EPS25858.1 - 0.00018 20.4 0.0 0.00055 18.8 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1479) UPF0731 PF14982.6 EPS25858.1 - 0.16 12.1 0.0 0.5 10.6 0.0 1.8 1 0 0 1 1 1 0 UPF0731 family Transferase PF02458.15 EPS25859.1 - 2.9e-05 22.9 0.0 0.2 10.3 0.0 2.3 2 0 0 2 2 2 2 Transferase family NmrA PF05368.13 EPS25860.1 - 9.9e-29 100.5 0.0 1.3e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPS25860.1 - 3.1e-07 30.5 0.0 5e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EPS25860.1 - 0.011 15.9 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Trp_DMAT PF11991.8 EPS25861.1 - 1.6e-94 317.4 0.0 1.9e-94 317.1 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase NmrA PF05368.13 EPS25862.1 - 7.3e-37 127.2 0.0 9.5e-37 126.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPS25862.1 - 1.1e-13 51.6 0.0 1.5e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EPS25862.1 - 4.9e-06 25.8 0.0 6.8e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EPS25862.1 - 2.1e-05 24.1 0.0 3.1e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EPS25862.1 - 0.01 16.1 0.0 0.022 15.0 0.0 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 EPS25862.1 - 0.012 16.2 0.0 0.082 13.5 0.0 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent adh_short_C2 PF13561.6 EPS25863.1 - 1.6e-27 96.6 0.6 1.9e-27 96.3 0.6 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPS25863.1 - 3.2e-21 75.7 0.3 8.7e-21 74.3 0.1 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EPS25863.1 - 0.0051 16.8 0.2 0.0074 16.2 0.2 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_7 PF13241.6 EPS25863.1 - 0.01 16.3 0.1 0.16 12.4 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding TrkA_N PF02254.18 EPS25863.1 - 0.091 13.0 0.1 0.47 10.7 0.0 2.2 3 0 0 3 3 3 0 TrkA-N domain Epimerase PF01370.21 EPS25863.1 - 0.11 12.0 0.1 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family FAD_binding_3 PF01494.19 EPS25864.1 - 5.6e-15 55.4 2.9 7.7e-14 51.7 2.9 2.2 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EPS25864.1 - 1.7e-06 27.8 2.9 0.03 13.9 0.6 2.6 2 1 1 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EPS25864.1 - 9.1e-06 25.0 0.9 2.4e-05 23.6 0.1 2.0 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.14 EPS25864.1 - 0.0041 16.4 0.3 0.12 11.6 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EPS25864.1 - 0.0051 15.6 0.4 0.02 13.6 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 EPS25864.1 - 0.013 15.7 0.1 0.044 14.0 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EPS25864.1 - 0.07 12.2 0.3 4.1 6.4 0.1 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein GIDA PF01134.22 EPS25864.1 - 0.13 11.4 0.2 0.16 11.1 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EPS25864.1 - 0.19 11.0 0.3 0.43 9.9 0.3 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NmrA PF05368.13 EPS25865.1 - 2.4e-31 109.1 0.0 3.4e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPS25865.1 - 6e-08 32.8 0.0 8.4e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EPS25865.1 - 0.0001 22.6 0.0 0.00016 21.9 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 EPS25865.1 - 0.016 15.7 0.0 0.053 14.0 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EPS25865.1 - 0.064 12.2 0.0 0.21 10.6 0.0 1.7 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EPS25865.1 - 0.087 12.3 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Amino_oxidase PF01593.24 EPS25866.1 - 1.4e-38 133.3 0.0 1.8e-38 133.1 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EPS25866.1 - 1.6e-11 44.2 0.0 4e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EPS25866.1 - 0.00086 19.3 0.0 0.0019 18.2 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.24 EPS25866.1 - 0.0018 17.9 0.0 0.0027 17.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EPS25866.1 - 0.0063 15.8 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family PhyH PF05721.13 EPS25867.1 - 6.2e-19 69.1 0.0 9.6e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 EPS25867.1 - 0.0014 17.5 0.0 0.0026 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) ATP-gua_Ptrans PF00217.19 EPS25867.1 - 0.075 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 ATP:guanido phosphotransferase, C-terminal catalytic domain NmrA PF05368.13 EPS25868.1 - 4.4e-30 105.0 0.0 6.3e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPS25868.1 - 3.2e-12 46.7 0.0 5.2e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EPS25868.1 - 5.2e-05 22.8 0.0 7.2e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.18 EPS25868.1 - 0.00033 20.9 0.0 0.00052 20.3 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain Semialdhyde_dh PF01118.24 EPS25868.1 - 0.0013 19.2 0.0 0.0084 16.5 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EPS25868.1 - 0.002 17.2 0.0 0.0033 16.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 EPS25868.1 - 0.026 14.4 0.1 0.05 13.5 0.1 1.4 1 0 0 1 1 1 0 KR domain Methyltransf_25 PF13649.6 EPS25869.1 - 8.3e-10 39.3 0.1 2.1e-09 37.9 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPS25869.1 - 1.6e-06 28.8 0.0 2.9e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPS25869.1 - 5.2e-06 26.3 0.0 9.2e-06 25.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS25869.1 - 3.8e-05 24.2 0.1 9.8e-05 22.9 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPS25869.1 - 0.00057 19.8 0.0 0.0014 18.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPS25869.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PhyH PF05721.13 EPS25870.1 - 5.6e-18 66.0 0.1 1.9e-17 64.2 0.1 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 EPS25870.1 - 0.011 14.6 0.0 0.025 13.4 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1479) DUF3479 PF11965.8 EPS25870.1 - 0.031 14.4 0.1 0.052 13.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3479) Trp_DMAT PF11991.8 EPS25871.1 - 2.2e-93 313.6 0.0 2.6e-93 313.3 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Arch_fla_DE PF04659.13 EPS25871.1 - 0.00069 19.4 0.0 0.0016 18.3 0.0 1.6 1 0 0 1 1 1 1 Archaeal flagella protein p450 PF00067.22 EPS25872.1 - 1.4e-68 231.7 0.0 1.7e-68 231.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.23 EPS25873.1 - 1.2e-20 73.7 3.4 2.7e-20 72.5 3.4 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EPS25873.1 - 2.1e-08 34.1 0.0 4.2e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like LacI PF00356.21 EPS25873.1 - 0.06 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family AMP-binding PF00501.28 EPS25874.1 - 1.4e-134 448.9 0.0 6.5e-68 229.2 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme NAD_binding_4 PF07993.12 EPS25874.1 - 2.7e-38 131.6 0.0 6.6e-38 130.3 0.0 1.7 1 0 0 1 1 1 1 Male sterility protein Condensation PF00668.20 EPS25874.1 - 7e-32 110.7 0.0 2e-31 109.2 0.0 1.8 1 1 0 1 1 1 1 Condensation domain PP-binding PF00550.25 EPS25874.1 - 1.3e-17 63.9 0.4 7.1e-08 32.7 0.3 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site Epimerase PF01370.21 EPS25874.1 - 0.0001 21.9 0.0 0.00095 18.7 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EPS25874.1 - 0.0019 17.3 0.0 0.7 8.8 0.0 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EPS25874.1 - 0.062 13.2 0.5 16 5.3 0.1 3.3 3 0 0 3 3 3 0 NAD(P)H-binding HAD PF12710.7 EPS25874.1 - 0.15 12.4 0.0 0.58 10.5 0.0 2.0 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase p450 PF00067.22 EPS25875.1 - 3.4e-43 148.1 0.0 4.1e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 P5CR_dimer PF14748.6 EPS25876.1 - 5.1e-24 84.5 0.0 6.8e-24 84.1 0.0 1.2 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation Glyco_tranf_2_3 PF13641.6 EPS25877.1 - 1.3e-12 48.1 1.7 1.7e-12 47.7 1.7 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EPS25877.1 - 2.7e-08 33.8 0.1 3.9e-08 33.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EPS25877.1 - 0.0083 15.6 0.1 2.8 7.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 MFS_1 PF07690.16 EPS25878.1 - 6.1e-33 114.2 27.3 6.1e-33 114.2 27.3 2.5 1 1 2 3 3 3 2 Major Facilitator Superfamily Tail_VII PF17091.5 EPS25878.1 - 0.32 10.9 2.2 0.59 10.1 0.1 2.7 3 0 0 3 3 3 0 Inovirus G7P protein Abhydrolase_6 PF12697.7 EPS25879.1 - 0.0027 18.4 0.1 0.0027 18.4 0.1 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPS25879.1 - 0.004 16.5 0.0 0.017 14.4 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF676 PF05057.14 EPS25879.1 - 0.11 12.0 0.1 0.19 11.2 0.1 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Peptidase_S9 PF00326.21 EPS25879.1 - 0.15 11.5 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family HisG PF01634.18 EPS25880.1 - 9.3e-55 185.0 0.4 1.6e-54 184.2 0.4 1.4 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 EPS25880.1 - 3.6e-28 97.5 0.4 7.3e-28 96.5 0.4 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.11 EPS25880.1 - 0.0023 17.9 0.2 0.0034 17.3 0.2 1.3 1 0 0 1 1 1 1 NMT1/THI5 like Ribosomal_S28e PF01200.18 EPS25881.1 - 8.4e-32 109.0 1.7 9.3e-32 108.8 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e MutS_V PF00488.21 EPS25882.1 - 3.2e-73 245.8 0.1 6.6e-73 244.8 0.1 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EPS25882.1 - 6.9e-36 124.3 0.1 2.5e-35 122.5 0.1 2.0 1 1 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EPS25882.1 - 3.9e-30 104.4 0.0 9.2e-30 103.2 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EPS25882.1 - 1.1e-08 35.5 0.0 4e-08 33.6 0.0 2.0 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 EPS25882.1 - 0.0021 18.4 0.1 0.0048 17.2 0.1 1.6 1 0 0 1 1 1 1 MutS family domain IV DUF4911 PF16256.5 EPS25882.1 - 0.059 13.4 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4911) zf-C2H2_2 PF12756.7 EPS25883.1 - 0.044 14.1 0.2 0.086 13.2 0.2 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Prenyltrans PF00432.21 EPS25884.1 - 7.7e-54 179.1 6.2 7.1e-11 41.6 0.0 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 EPS25884.1 - 0.00031 19.9 0.0 0.062 12.4 0.0 3.5 3 1 1 4 4 4 1 Squalene-hopene cyclase N-terminal domain SQHop_cyclase_C PF13243.6 EPS25884.1 - 0.0009 18.4 0.1 0.11 11.6 0.0 2.8 1 1 1 2 2 2 2 Squalene-hopene cyclase C-terminal domain RhoGAP PF00620.27 EPS25887.1 - 4.9e-30 104.4 0.0 9.8e-30 103.4 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain RRS1 PF04939.12 EPS25888.1 - 6.5e-56 188.7 2.1 7.8e-56 188.4 2.1 1.1 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) DAP3 PF10236.9 EPS25889.1 - 8.1e-100 334.0 0.0 9.9e-100 333.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 Fungal_trans PF04082.18 EPS25890.1 - 8.4e-20 70.9 0.0 1.3e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS25890.1 - 5.4e-07 29.6 10.7 1e-06 28.7 10.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Trimer_CC PF08954.11 EPS25890.1 - 0.11 12.1 0.2 0.32 10.6 0.2 1.8 1 0 0 1 1 1 0 Trimerisation motif Amidohydro_2 PF04909.14 EPS25891.1 - 1.1e-19 71.4 0.2 4.8e-19 69.2 0.2 1.9 1 1 0 1 1 1 1 Amidohydrolase AA_permease_2 PF13520.6 EPS25892.1 - 3.8e-49 167.7 51.6 3.7e-48 164.4 51.6 1.9 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPS25892.1 - 1.7e-23 83.0 35.5 1.7e-23 83.0 35.5 1.4 2 0 0 2 2 2 1 Amino acid permease AA_permease PF00324.21 EPS25894.1 - 5.9e-131 437.3 39.6 7.2e-131 437.1 39.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EPS25894.1 - 8.4e-35 120.4 44.3 1.1e-34 120.0 44.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 EPS25894.1 - 0.072 11.9 1.2 0.16 10.8 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) HDOD PF08668.12 EPS25894.1 - 0.18 11.3 0.4 0.29 10.6 0.4 1.2 1 0 0 1 1 1 0 HDOD domain ADH_N PF08240.12 EPS25897.1 - 4e-25 87.8 0.3 7.7e-25 86.9 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPS25897.1 - 9e-25 87.1 0.3 1.3e-24 86.6 0.3 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EPS25897.1 - 0.0028 17.5 0.1 0.0099 15.8 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 EPS25897.1 - 0.0039 18.2 0.0 0.008 17.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PALP PF00291.25 EPS25897.1 - 0.22 10.9 3.2 0.32 10.4 0.2 2.0 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme TRAP_alpha PF03896.16 EPS25900.1 - 1 8.5 2.5 1.5 7.9 2.5 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PBP1_TM PF14812.6 EPS25900.1 - 1.5 9.2 6.5 4 7.9 6.5 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CobT PF06213.12 EPS25900.1 - 4 6.7 12.6 13 5.1 11.8 1.9 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.12 EPS25900.1 - 4.8 5.3 11.4 6.6 4.8 11.4 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 EPS25900.1 - 5.6 6.2 10.8 8.7 5.6 10.8 1.2 1 0 0 1 1 1 0 NOA36 protein FGase PF05013.12 EPS25902.1 - 0.075 13.2 1.4 10 6.3 0.0 2.7 3 0 0 3 3 3 0 N-formylglutamate amidohydrolase G10 PF01125.17 EPS25902.1 - 0.15 11.8 0.4 0.31 10.8 0.4 1.5 1 0 0 1 1 1 0 G10 protein SET PF00856.28 EPS25903.1 - 6.4e-07 29.9 0.0 4.2e-06 27.3 0.0 2.4 1 1 0 1 1 1 1 SET domain SAP PF02037.27 EPS25903.1 - 1.8e-05 24.4 1.1 6.5e-05 22.6 0.5 2.3 2 0 0 2 2 2 1 SAP domain Aldo_ket_red PF00248.21 EPS25904.1 - 3.9e-68 229.8 0.0 4.5e-68 229.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Claudin_3 PF06653.11 EPS25904.1 - 0.055 13.4 0.0 0.092 12.7 0.0 1.3 1 0 0 1 1 1 0 Tight junction protein, Claudin-like AAA PF00004.29 EPS25905.1 - 1.1e-12 48.5 0.0 4.6e-12 46.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EPS25905.1 - 1.1e-11 45.2 0.0 4.1e-11 43.3 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 EPS25905.1 - 2e-11 44.6 1.0 1.1e-10 42.2 0.2 2.5 2 1 0 2 2 2 1 AAA ATPase domain Cdc6_C PF09079.11 EPS25905.1 - 2.2e-07 30.8 0.1 1.1e-06 28.5 0.0 2.3 2 1 0 2 2 2 1 CDC6, C terminal winged helix domain NTPase_1 PF03266.15 EPS25905.1 - 8.2e-06 25.8 0.0 1.8e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 NTPase TniB PF05621.11 EPS25905.1 - 0.0002 20.8 0.0 0.0004 19.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein AAA_7 PF12775.7 EPS25905.1 - 0.00046 19.8 0.0 0.001 18.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_lid_10 PF17872.1 EPS25905.1 - 0.00094 19.3 0.0 0.0019 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA lid domain AAA_19 PF13245.6 EPS25905.1 - 0.003 17.9 0.0 0.0077 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 EPS25905.1 - 0.0035 17.3 0.0 0.0071 16.3 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 EPS25905.1 - 0.0037 17.6 0.0 0.0075 16.6 0.0 1.5 1 0 0 1 1 1 1 RNA helicase T2SSE PF00437.20 EPS25905.1 - 0.0079 15.3 0.0 0.017 14.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein TIP49 PF06068.13 EPS25905.1 - 0.0087 15.3 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain DUF815 PF05673.13 EPS25905.1 - 0.011 15.0 0.0 0.022 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Rad17 PF03215.15 EPS25905.1 - 0.011 15.6 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_11 PF13086.6 EPS25905.1 - 0.014 15.2 0.1 0.085 12.6 0.1 2.1 1 1 0 1 1 1 0 AAA domain PIF1 PF05970.14 EPS25905.1 - 0.023 13.9 0.0 0.04 13.1 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA_14 PF13173.6 EPS25905.1 - 0.069 13.2 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AFG1_ATPase PF03969.16 EPS25905.1 - 0.074 11.9 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase Sigma54_activat PF00158.26 EPS25905.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain RsgA_GTPase PF03193.16 EPS25905.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase DUF2075 PF09848.9 EPS25905.1 - 0.15 11.2 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.6 EPS25905.1 - 0.16 12.2 0.0 1.6 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain Thioredoxin_7 PF13899.6 EPS25906.1 - 3.7e-18 65.5 0.2 9.2e-18 64.2 0.1 1.7 2 0 0 2 2 2 1 Thioredoxin-like UBA_4 PF14555.6 EPS25906.1 - 3.4e-14 52.4 0.1 8e-14 51.2 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 EPS25906.1 - 7.7e-08 32.4 0.0 4e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 UBX domain Thioredox_DsbH PF03190.15 EPS25906.1 - 0.0087 16.0 0.1 0.014 15.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_2 PF13098.6 EPS25906.1 - 0.011 16.1 0.1 0.032 14.7 0.1 1.9 1 1 0 1 1 1 0 Thioredoxin-like domain Pkinase PF00069.25 EPS25907.1 - 1.5e-70 237.5 0.0 2.1e-70 237.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS25907.1 - 7.1e-51 173.0 0.0 1.1e-50 172.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EPS25907.1 - 0.00013 20.9 0.0 0.00027 19.8 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EPS25907.1 - 0.0032 16.8 0.0 0.009 15.3 0.0 1.7 2 0 0 2 2 2 1 Kinase-like ABC1 PF03109.16 EPS25907.1 - 0.089 13.0 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 ABC1 family RhoGAP PF00620.27 EPS25908.1 - 1.3e-14 54.3 0.3 3.4e-14 52.9 0.3 1.7 1 0 0 1 1 1 1 RhoGAP domain DEP PF00610.21 EPS25908.1 - 7.1e-13 48.4 0.0 1.5e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) FCH PF00611.23 EPS25908.1 - 1.7e-07 31.4 0.0 5.6e-07 29.7 0.0 2.0 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Phage_TAC_8 PF10666.9 EPS25908.1 - 0.008 16.5 0.5 0.033 14.5 0.1 2.2 2 0 0 2 2 2 1 Phage tail assembly chaperone protein Gp14 ()A118 DUF5343 PF17278.2 EPS25908.1 - 0.058 13.5 0.1 0.13 12.4 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5343) AA_permease PF00324.21 EPS25909.1 - 8.3e-147 489.6 40.6 9.4e-147 489.4 40.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EPS25909.1 - 1.1e-34 120.1 40.6 1.3e-34 119.8 40.6 1.0 1 0 0 1 1 1 1 Amino acid permease DUF4781 PF16013.5 EPS25909.1 - 0.006 15.4 0.3 0.011 14.6 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4781) LSM PF01423.22 EPS25912.1 - 7.2e-21 73.7 0.0 8e-21 73.5 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EPS25912.1 - 0.044 13.9 0.0 0.052 13.7 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain DNA_pol_A_exo1 PF01612.20 EPS25913.1 - 2.6e-16 59.8 0.0 4.8e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease Pex2_Pex12 PF04757.14 EPS25914.1 - 3.3e-45 154.4 7.4 4.4e-45 154.0 7.4 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 EPS25914.1 - 3.3e-11 42.8 8.7 5.5e-11 42.1 8.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EPS25914.1 - 1e-10 41.7 9.7 1.6e-10 41.1 9.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EPS25914.1 - 1.1e-10 41.2 6.7 1.7e-10 40.6 6.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPS25914.1 - 1.6e-10 40.7 6.5 2.5e-10 40.1 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPS25914.1 - 1.6e-07 31.3 7.2 3.3e-07 30.2 7.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EPS25914.1 - 1.6e-07 31.1 6.9 2.7e-07 30.3 6.9 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EPS25914.1 - 1.2e-06 28.4 6.4 2e-06 27.7 6.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EPS25914.1 - 6.1e-06 26.4 6.7 1.3e-05 25.4 6.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EPS25914.1 - 2.4e-05 24.4 8.0 4.2e-05 23.6 8.0 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 EPS25914.1 - 0.0043 17.2 6.4 0.0079 16.3 6.4 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_6 PF14835.6 EPS25914.1 - 0.052 13.4 3.2 0.099 12.5 3.2 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 EPS25914.1 - 0.062 13.4 3.5 0.11 12.6 3.3 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EPS25914.1 - 0.13 12.0 7.2 0.28 11.0 7.2 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FYVE PF01363.21 EPS25914.1 - 0.38 10.9 6.3 1.2 9.3 6.3 1.9 1 1 0 1 1 1 0 FYVE zinc finger IBR PF01485.21 EPS25914.1 - 4.7 7.5 7.8 13 6.1 7.8 1.8 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain EXS PF03124.14 EPS25915.1 - 1e-97 327.5 20.1 1.2e-97 327.3 20.1 1.0 1 0 0 1 1 1 1 EXS family Presenilin PF01080.17 EPS25916.1 - 0.0093 14.8 1.8 0.012 14.4 1.8 1.3 1 0 0 1 1 1 1 Presenilin Macoilin PF09726.9 EPS25916.1 - 0.023 13.3 12.7 0.027 13.0 12.7 1.2 1 0 0 1 1 1 0 Macoilin family Miga PF10265.9 EPS25916.1 - 0.22 10.4 7.7 0.29 10.1 7.7 1.2 1 0 0 1 1 1 0 Mitoguardin SpoIIIAH PF12685.7 EPS25916.1 - 0.77 9.6 18.2 1.5 8.6 18.2 1.4 1 0 0 1 1 1 0 SpoIIIAH-like protein ATP-synt_S1 PF05827.12 EPS25917.1 - 0.00012 22.0 0.0 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) OAD_gamma PF04277.13 EPS25917.1 - 0.15 12.7 0.4 0.25 12.0 0.4 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Nop25 PF09805.9 EPS25918.1 - 2.3e-37 128.5 17.6 2.3e-37 128.5 17.6 2.6 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) FCP1_C PF09309.10 EPS25918.1 - 0.9 9.4 24.5 2.6 7.8 10.2 2.1 2 0 0 2 2 2 0 FCP1, C-terminal DUF4522 PF15022.6 EPS25918.1 - 4 7.7 10.9 0.087 13.1 2.6 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF4522) Tropomyosin_1 PF12718.7 EPS25919.1 - 6.6e-53 178.7 38.7 7.7e-53 178.5 38.7 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.20 EPS25919.1 - 4.6e-09 36.0 36.4 0.00017 21.0 14.8 2.9 1 1 1 2 2 2 2 Tropomyosin ADIP PF11559.8 EPS25919.1 - 0.00086 19.4 34.1 0.054 13.6 16.8 2.8 1 1 2 3 3 3 2 Afadin- and alpha -actinin-Binding KLRAQ PF10205.9 EPS25919.1 - 0.0012 19.1 27.2 0.0027 17.9 13.6 2.9 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein Cast PF10174.9 EPS25919.1 - 0.0016 16.8 16.0 0.0016 16.8 16.0 1.9 1 1 1 2 2 2 1 RIM-binding protein of the cytomatrix active zone Laminin_II PF06009.12 EPS25919.1 - 0.0027 17.8 21.5 0.0048 16.9 8.2 2.1 1 1 1 2 2 2 1 Laminin Domain II FlaC_arch PF05377.11 EPS25919.1 - 0.0051 17.2 22.4 0.093 13.1 4.5 4.4 3 2 1 4 4 4 2 Flagella accessory protein C (FlaC) DUF3450 PF11932.8 EPS25919.1 - 0.0065 15.8 30.7 0.045 13.1 15.9 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3450) KASH_CCD PF14662.6 EPS25919.1 - 0.0095 15.8 33.6 0.016 15.1 33.4 1.8 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Fez1 PF06818.15 EPS25919.1 - 0.0096 16.4 30.4 0.013 16.0 30.4 1.1 1 0 0 1 1 1 1 Fez1 Myosin_tail_1 PF01576.19 EPS25919.1 - 0.013 13.3 34.0 0.016 13.1 34.0 1.0 1 0 0 1 1 1 0 Myosin tail DUF4200 PF13863.6 EPS25919.1 - 0.017 15.5 35.6 0.071 13.5 17.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Spc7 PF08317.11 EPS25919.1 - 0.019 13.8 36.0 0.53 9.1 17.5 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein GAS PF13851.6 EPS25919.1 - 0.021 14.2 34.1 0.17 11.2 24.7 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 EPS25919.1 - 0.025 14.8 36.8 3.7 7.7 26.8 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Taxilin PF09728.9 EPS25919.1 - 0.038 13.2 28.7 0.15 11.2 9.5 2.0 1 1 1 2 2 2 0 Myosin-like coiled-coil protein Uso1_p115_C PF04871.13 EPS25919.1 - 0.04 14.3 38.1 0.79 10.1 17.7 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region SOGA PF11365.8 EPS25919.1 - 0.058 14.5 25.5 0.66 11.1 1.2 3.4 2 1 1 3 3 3 0 Protein SOGA TACC_C PF05010.14 EPS25919.1 - 0.072 12.9 28.1 1.1 9.0 3.6 2.4 1 1 2 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal MAD PF05557.13 EPS25919.1 - 0.075 11.4 32.2 0.17 10.2 32.2 1.5 1 1 0 1 1 1 0 Mitotic checkpoint protein DUF1664 PF07889.12 EPS25919.1 - 0.082 13.0 17.0 0.43 10.6 4.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF724 PF05266.14 EPS25919.1 - 0.12 12.2 26.9 0.14 12.0 9.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF724) bZIP_1 PF00170.21 EPS25919.1 - 0.14 12.3 31.4 1.9 8.6 0.5 4.4 2 1 2 4 4 4 0 bZIP transcription factor APG6_N PF17675.1 EPS25919.1 - 0.15 12.5 42.8 1.2 9.7 27.9 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF4201 PF13870.6 EPS25919.1 - 0.17 11.6 28.7 1.8 8.2 10.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) TMF_TATA_bd PF12325.8 EPS25919.1 - 0.2 11.9 30.6 0.77 10.0 17.3 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Fmp27_WPPW PF10359.9 EPS25919.1 - 0.27 10.1 27.9 0.14 11.0 11.0 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain FAM76 PF16046.5 EPS25919.1 - 0.28 10.5 24.6 0.87 8.9 10.1 2.0 1 1 1 2 2 2 0 FAM76 protein TMF_DNA_bd PF12329.8 EPS25919.1 - 0.31 11.1 37.3 0.32 11.0 14.8 4.0 1 1 3 4 4 3 0 TATA element modulatory factor 1 DNA binding HAP1_N PF04849.13 EPS25919.1 - 0.43 9.7 31.2 39 3.3 31.3 2.3 1 1 0 1 1 1 0 HAP1 N-terminal conserved region Jnk-SapK_ap_N PF09744.9 EPS25919.1 - 0.79 9.9 37.0 0.25 11.6 23.6 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 TPR_MLP1_2 PF07926.12 EPS25919.1 - 0.79 9.8 40.0 0.47 10.5 14.4 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Syntaxin-6_N PF09177.11 EPS25919.1 - 0.9 10.1 22.6 1.7 9.2 3.4 3.1 1 1 3 4 4 4 0 Syntaxin 6, N-terminal Phage_GPO PF05929.11 EPS25919.1 - 1 8.9 24.1 0.43 10.2 17.4 2.0 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase MS_channel PF00924.18 EPS25919.1 - 1.1 8.8 2.5 1 8.9 1.4 1.5 1 1 0 1 1 1 0 Mechanosensitive ion channel ERM PF00769.19 EPS25919.1 - 1.2 8.9 40.8 2.1 8.1 17.8 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family BST2 PF16716.5 EPS25919.1 - 1.2 9.7 30.1 0.21 12.2 8.0 3.5 1 1 2 3 3 3 0 Bone marrow stromal antigen 2 Mod_r PF07200.13 EPS25919.1 - 1.3 9.1 31.1 3.1 7.9 1.9 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein LPP PF04728.13 EPS25919.1 - 1.6 9.2 15.4 4.1e+02 1.5 0.1 4.0 2 1 1 3 3 3 0 Lipoprotein leucine-zipper CASP_C PF08172.12 EPS25919.1 - 2 7.7 26.1 0.19 11.0 2.3 2.5 1 1 0 2 2 2 0 CASP C terminal WDCP PF15390.6 EPS25919.1 - 2.1 6.7 17.2 2.5 6.4 17.2 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family XhlA PF10779.9 EPS25919.1 - 2.2 8.6 29.7 1.1 9.6 2.1 4.1 1 1 2 4 4 4 0 Haemolysin XhlA NABP PF07990.12 EPS25919.1 - 2.4 7.6 7.2 2.6 7.5 7.2 1.1 1 0 0 1 1 1 0 Nucleic acid binding protein NABP ZapB PF06005.12 EPS25919.1 - 2.5 8.6 42.6 52 4.4 3.5 4.3 1 1 2 3 3 3 0 Cell division protein ZapB FUSC PF04632.12 EPS25919.1 - 2.7 6.4 13.2 3.5 6.0 13.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family PspA_IM30 PF04012.12 EPS25919.1 - 2.8 7.4 34.5 0.42 10.1 6.0 2.1 1 1 1 2 2 2 0 PspA/IM30 family DUF4972 PF16342.5 EPS25919.1 - 2.9 7.6 10.7 2 8.1 7.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4972) BRE1 PF08647.11 EPS25919.1 - 3.1 8.0 33.0 2.5 8.2 7.1 2.3 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Striatin PF08232.12 EPS25919.1 - 3.9 8.0 29.5 3.4 8.3 2.4 2.4 1 1 0 2 2 2 0 Striatin family AAA_13 PF13166.6 EPS25919.1 - 4.4 5.8 27.0 0.27 9.8 10.2 2.2 1 1 1 2 2 2 0 AAA domain HAUS-augmin3 PF14932.6 EPS25919.1 - 4.5 6.8 31.3 1.8 8.0 11.5 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 Cortex-I_coil PF09304.10 EPS25919.1 - 4.7 7.5 25.6 9.2 6.5 0.3 3.3 1 1 2 3 3 3 0 Cortexillin I, coiled coil UPF0242 PF06785.11 EPS25919.1 - 4.9 7.2 34.4 4 7.5 18.0 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus YabA PF06156.13 EPS25919.1 - 4.9 7.8 27.1 3.1 8.5 11.8 3.1 1 1 2 3 3 3 0 Initiation control protein YabA CtIP_N PF10482.9 EPS25919.1 - 4.9 7.2 27.4 1.1e+02 2.8 3.8 3.1 1 1 1 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain DUF812 PF05667.11 EPS25919.1 - 5.2 5.8 32.9 19 4.0 32.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF812) CENP-H PF05837.12 EPS25919.1 - 5.8 7.4 29.9 4.1 7.9 14.6 3.0 1 1 2 3 3 3 0 Centromere protein H (CENP-H) SlyX PF04102.12 EPS25919.1 - 5.8 7.6 27.9 1.7 9.3 4.3 4.2 1 1 3 4 4 3 0 SlyX Nup88 PF10168.9 EPS25919.1 - 6 4.6 24.4 7.3 4.3 24.4 1.1 1 0 0 1 1 1 0 Nuclear pore component Ax_dynein_light PF10211.9 EPS25919.1 - 6.5 6.7 34.9 12 5.8 6.3 3.7 1 1 2 3 3 3 0 Axonemal dynein light chain PI3K_P85_iSH2 PF16454.5 EPS25919.1 - 6.9 6.2 28.5 18 4.9 28.6 1.6 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain FapA PF03961.13 EPS25919.1 - 7.7 5.0 26.4 5.8 5.4 11.3 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A DUF3584 PF12128.8 EPS25919.1 - 8.7 3.7 33.0 19 2.6 33.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF16 PF01519.16 EPS25919.1 - 8.7 6.9 24.1 2.5 8.6 6.5 3.1 1 1 2 3 3 3 0 Protein of unknown function DUF16 DUF4988 PF16378.5 EPS25919.1 - 9.4 5.9 10.2 3.8 7.1 1.2 3.3 1 1 2 3 3 3 0 Domain of unknown function HMMR_N PF15905.5 EPS25919.1 - 9.4 5.6 33.7 1.4e+02 1.8 33.7 2.1 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal CMAS PF02353.20 EPS25921.1 - 1.7e-61 207.9 0.1 2.2e-61 207.5 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 EPS25921.1 - 3.5e-08 34.0 0.0 7.9e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPS25921.1 - 4.1e-08 33.2 0.0 6.9e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS25921.1 - 1.1e-07 32.4 0.0 2.2e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPS25921.1 - 0.0023 18.7 0.0 0.0045 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 EPS25921.1 - 0.0038 16.8 0.0 0.0072 15.9 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 PCMT PF01135.19 EPS25921.1 - 0.038 13.7 0.0 0.061 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 EPS25921.1 - 0.058 12.9 0.0 0.088 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.6 EPS25921.1 - 0.09 12.6 0.0 0.19 11.5 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Fungal_trans_2 PF11951.8 EPS25922.1 - 9.7e-45 153.0 0.2 1.4e-44 152.5 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS25922.1 - 0.0053 16.8 6.5 0.012 15.7 6.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pex24p PF06398.11 EPS25923.1 - 7.3e-101 337.8 2.6 1.1e-100 337.2 2.6 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Syntaxin-18_N PF10496.9 EPS25923.1 - 0.38 11.0 0.1 0.38 11.0 0.1 2.4 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus Pam16 PF03656.13 EPS25924.1 - 5.2e-34 117.0 0.4 6.7e-34 116.6 0.4 1.1 1 0 0 1 1 1 1 Pam16 Aldo_ket_red PF00248.21 EPS25925.1 - 5.2e-65 219.5 0.0 6.9e-65 219.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family NTP_transf_2 PF01909.23 EPS25926.1 - 4.2e-11 43.0 0.0 8.2e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 EPS25926.1 - 1.3e-10 41.3 1.6 4.4e-10 39.6 1.6 1.9 1 1 0 1 1 1 1 Cid1 family poly A polymerase Polbeta PF18765.1 EPS25926.1 - 0.06 13.4 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase PRKCSH-like PF12999.7 EPS25928.1 - 3.7e-46 157.1 9.3 2.1e-27 96.1 0.5 3.0 4 0 0 4 4 4 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 EPS25928.1 - 1e-31 109.7 4.1 1.1e-31 109.6 1.6 2.2 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 EPS25928.1 - 2.3e-09 38.1 2.2 2.7e-09 37.9 0.4 2.1 2 0 0 2 2 1 1 Glucosidase II beta subunit-like protein BST2 PF16716.5 EPS25928.1 - 0.0015 19.0 11.8 0.32 11.6 2.6 3.4 3 0 0 3 3 3 1 Bone marrow stromal antigen 2 Lebercilin PF15619.6 EPS25928.1 - 0.0032 17.2 5.8 0.0032 17.2 5.8 2.5 2 1 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease ATG27 PF09451.10 EPS25928.1 - 0.0081 16.0 1.7 0.0081 16.0 1.7 1.5 2 0 0 2 2 2 1 Autophagy-related protein 27 Angiomotin_C PF12240.8 EPS25928.1 - 0.015 14.9 0.9 0.015 14.9 0.9 2.1 3 0 0 3 3 3 0 Angiomotin C terminal Fib_alpha PF08702.10 EPS25928.1 - 0.086 13.0 5.7 4.5 7.5 0.1 3.2 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family BRE1 PF08647.11 EPS25928.1 - 0.12 12.5 8.6 2.6 8.2 2.1 3.0 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase PRCC PF10253.9 EPS25928.1 - 0.23 12.2 3.7 0.27 12.0 1.7 2.1 2 1 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting MscS_porin PF12795.7 EPS25928.1 - 0.55 9.7 9.2 0.41 10.2 2.2 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain NPV_P10 PF05531.12 EPS25928.1 - 0.68 10.4 3.4 31 5.1 0.2 3.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF349 PF03993.12 EPS25928.1 - 1.7 9.0 16.4 0.086 13.1 8.4 2.7 3 0 0 3 3 2 0 Domain of Unknown Function (DUF349) DUF4407 PF14362.6 EPS25928.1 - 1.7 7.9 15.1 17 4.6 14.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) KfrA_N PF11740.8 EPS25928.1 - 2.7 8.7 16.7 12 6.6 0.9 3.5 3 0 0 3 3 3 0 Plasmid replication region DNA-binding N-term FTA4 PF13093.6 EPS25928.1 - 3.3 7.5 5.7 3.5 7.5 2.5 2.5 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 SlyX PF04102.12 EPS25928.1 - 4.4 8.0 9.6 28 5.4 0.1 3.6 3 0 0 3 3 3 0 SlyX DUF641 PF04859.12 EPS25928.1 - 6.1 7.2 11.0 6.6 7.1 4.2 2.8 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) Rtf2 PF04641.12 EPS25929.1 - 1.4e-69 234.4 1.2 1.5e-69 234.3 1.2 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 EPS25929.1 - 3.8e-09 36.2 0.0 0.0032 17.3 0.0 2.8 2 1 1 3 3 3 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EPS25929.1 - 0.0013 18.7 0.5 0.0032 17.5 0.1 2.0 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EPS25929.1 - 0.0015 18.5 0.1 0.003 17.5 0.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EPS25929.1 - 0.025 14.9 0.1 0.086 13.2 0.0 1.9 1 1 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.6 EPS25929.1 - 0.053 13.4 0.6 0.76 9.7 0.2 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EPS25929.1 - 0.069 13.0 0.2 0.17 11.8 0.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EPS25929.1 - 0.07 13.0 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Plasmodium_Vir PF05795.11 EPS25929.1 - 1.3 8.3 4.5 2 7.8 4.5 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Ribosomal_L50 PF10501.9 EPS25930.1 - 1.1e-11 44.9 0.0 1.7e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal subunit 39S Thiolase_N PF00108.23 EPS25931.1 - 8.6e-74 248.2 0.7 1.2e-73 247.7 0.7 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EPS25931.1 - 1.4e-45 153.9 0.7 3.5e-45 152.6 0.7 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain Peptidase_M15_3 PF08291.11 EPS25931.1 - 0.14 12.3 0.3 4.3 7.5 0.0 2.5 2 0 0 2 2 2 0 Peptidase M15 Oxidored_molyb PF00174.19 EPS25932.1 - 1.4e-34 119.2 0.0 2.2e-34 118.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EPS25932.1 - 9.8e-21 74.2 0.1 1.9e-20 73.3 0.1 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Big_7 PF17957.1 EPS25932.1 - 0.06 14.1 0.3 0.1 13.4 0.3 1.3 1 0 0 1 1 1 0 Bacterial Ig domain zf-RING_2 PF13639.6 EPS25933.1 - 1.2e-11 44.7 5.2 2.3e-11 43.8 5.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EPS25933.1 - 4.2e-07 29.6 2.5 9.4e-07 28.5 2.5 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 EPS25933.1 - 8.4e-07 29.2 4.7 2.1e-06 27.9 4.7 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EPS25933.1 - 9.3e-07 28.6 5.3 1.7e-06 27.8 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPS25933.1 - 6.6e-06 25.9 2.1 1.3e-05 24.9 2.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EPS25933.1 - 1.2e-05 25.2 1.7 2.2e-05 24.3 1.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EPS25933.1 - 3.2e-05 23.9 1.3 0.00019 21.4 0.5 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EPS25933.1 - 5.9e-05 23.0 3.4 8.2e-05 22.6 3.4 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EPS25933.1 - 0.00034 20.4 1.9 0.00034 20.4 1.9 1.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EPS25933.1 - 0.0012 18.4 2.1 0.0012 18.4 2.1 1.7 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 EPS25933.1 - 0.0012 18.6 6.7 0.0022 17.8 5.1 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EPS25933.1 - 0.019 14.7 1.7 0.019 14.7 1.7 1.9 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Vps39_2 PF10367.9 EPS25933.1 - 0.067 13.7 1.1 0.64 10.5 0.5 2.1 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-C3H2C3 PF17122.5 EPS25933.1 - 0.11 12.6 3.4 0.38 10.8 3.4 1.9 1 1 0 1 1 1 0 Zinc-finger Rad50_zn_hook PF04423.14 EPS25933.1 - 0.13 12.1 0.1 0.25 11.2 0.1 1.4 1 0 0 1 1 1 0 Rad50 zinc hook motif RINGv PF12906.7 EPS25933.1 - 0.26 11.4 5.5 0.12 12.5 2.0 2.2 2 1 0 2 2 2 0 RING-variant domain PHD PF00628.29 EPS25933.1 - 0.95 9.4 4.8 0.34 10.8 1.9 1.8 2 0 0 2 2 2 0 PHD-finger zf-RING-like PF08746.11 EPS25933.1 - 3 8.2 6.2 11 6.4 6.2 2.1 1 1 0 1 1 1 0 RING-like domain RNase_H PF00075.24 EPS25934.1 - 5.3e-17 62.3 0.0 9.1e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 EPS25934.1 - 0.00013 21.8 0.2 0.35 10.7 0.3 3.1 2 1 0 2 2 2 2 Reverse transcriptase-like RNase_H PF00075.24 EPS25935.1 - 5.6e-15 55.8 0.0 1.1e-14 54.8 0.0 1.5 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.6 EPS25935.1 - 8.5e-05 22.4 0.0 0.16 11.8 0.0 3.0 3 0 0 3 3 3 2 Reverse transcriptase-like DAHP_synth_1 PF00793.20 EPS25937.1 - 2.4e-98 328.4 0.0 2.9e-98 328.1 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family COX14 PF14880.6 EPS25938.1 - 2.7e-18 65.6 0.2 2.7e-18 65.6 0.2 2.1 2 0 0 2 2 2 1 Cytochrome oxidase c assembly Pex14_N PF04695.13 EPS25938.1 - 0.016 15.9 7.7 0.15 12.7 1.5 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ECM11 PF15463.6 EPS25938.1 - 0.1 13.1 0.1 0.1 13.1 0.1 2.1 2 1 1 3 3 3 0 Extracellular mutant protein 11 DUF2458 PF10454.9 EPS25939.1 - 4.8e-63 211.9 0.5 7e-63 211.3 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) DUF1331 PF07048.11 EPS25939.1 - 0.071 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) CobW_C PF07683.14 EPS25939.1 - 0.072 13.0 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain NLPC_P60 PF00877.19 EPS25940.1 - 1.7e-18 66.6 0.0 2.7e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 NlpC/P60 family Amidase_5 PF05382.13 EPS25940.1 - 6.7e-06 26.1 0.5 9.7e-06 25.5 0.1 1.5 1 1 0 1 1 1 1 Bacteriophage peptidoglycan hydrolase SH3_3 PF08239.11 EPS25940.1 - 0.02 15.2 0.1 0.047 14.0 0.1 1.6 1 1 0 1 1 1 0 Bacterial SH3 domain DUF1175 PF06672.11 EPS25940.1 - 0.1 12.2 0.0 13 5.3 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1175) Serglycin PF04360.12 EPS25940.1 - 0.37 10.7 6.1 1 9.3 5.9 1.8 2 0 0 2 2 2 0 Serglycin F-box PF00646.33 EPS25941.1 - 4.2e-06 26.5 0.1 1.3e-05 24.9 0.1 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EPS25941.1 - 2.5e-05 24.1 0.4 7e-05 22.6 0.1 1.9 2 0 0 2 2 2 1 F-box-like Hexokinase_2 PF03727.16 EPS25942.1 - 4.7e-58 196.5 0.0 6.6e-58 196.0 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EPS25942.1 - 1.7e-44 152.2 0.0 2.5e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Arylsulfotran_2 PF14269.6 EPS25943.1 - 5e-44 150.9 1.4 8.7e-44 150.1 1.4 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 EPS25943.1 - 7.9e-17 61.2 1.1 4.4e-15 55.5 1.1 2.2 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) COesterase PF00135.28 EPS25944.1 - 1.9e-81 274.5 1.0 5.6e-81 273.0 1.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EPS25944.1 - 1.2e-06 28.6 0.0 2.7e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EPS25944.1 - 0.00065 19.2 0.2 0.0012 18.3 0.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF1749 PF08538.10 EPS25944.1 - 0.1 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Sugar_tr PF00083.24 EPS25945.1 - 6e-109 364.9 22.6 7e-109 364.7 22.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS25945.1 - 1.4e-17 63.7 39.4 6.8e-12 45.0 12.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_L12 PF00542.19 EPS25945.1 - 0.21 12.0 0.0 0.38 11.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L7/L12 C-terminal domain OppC_N PF12911.7 EPS25945.1 - 7.1 6.7 8.8 0.56 10.2 0.1 3.7 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C ADK PF00406.22 EPS25948.1 - 6.4e-44 149.7 0.0 8.6e-44 149.3 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EPS25948.1 - 9.7e-33 113.5 0.0 1.3e-32 113.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EPS25948.1 - 1.9e-07 31.7 0.0 2.7e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EPS25948.1 - 1.6e-06 27.9 0.0 0.016 14.9 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.6 EPS25948.1 - 1.7e-06 28.3 0.0 0.0048 17.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain SRP54 PF00448.22 EPS25948.1 - 0.035 13.7 0.0 0.064 12.9 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Ploopntkinase3 PF18751.1 EPS25948.1 - 0.099 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 PCI PF01399.27 EPS25949.1 - 7.5e-12 45.7 0.0 2e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 PCI domain eIF3m_C_helix PF18005.1 EPS25949.1 - 1e-11 44.3 2.6 2.6e-11 43.0 2.6 1.8 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix DNA_pol_phi PF04931.13 EPS25949.1 - 0.13 10.4 0.0 0.17 10.0 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase phi K_channel_TID PF07941.11 EPS25949.1 - 4.1 7.9 7.0 0.77 10.3 2.6 2.0 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain GSG-1 PF07803.11 EPS25950.1 - 0.054 13.4 0.7 0.054 13.4 0.7 2.2 2 1 0 2 2 2 0 GSG1-like protein Pacs-1 PF10254.9 EPS25950.1 - 0.13 11.2 1.9 0.15 11.0 1.9 1.1 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein CCDC24 PF15669.5 EPS25950.1 - 0.18 11.7 2.8 0.23 11.3 2.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family 4HBT PF03061.22 EPS25952.1 - 7.1e-09 35.9 0.1 1.2e-08 35.1 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 EPS25953.1 - 1.5e-55 189.2 2.1 1.7e-55 189.0 2.1 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Glyco_transf_20 PF00982.21 EPS25955.1 - 1.2e-160 535.4 0.0 1.6e-160 534.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EPS25955.1 - 5.5e-40 136.9 0.0 8.6e-40 136.3 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_5 PF08323.11 EPS25955.1 - 0.093 12.4 0.2 0.16 11.6 0.2 1.3 1 0 0 1 1 1 0 Starch synthase catalytic domain Stk19 PF10494.9 EPS25956.1 - 2e-89 299.5 0.0 2.5e-89 299.2 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 DUF3074 PF11274.8 EPS25957.1 - 5.3e-12 46.1 0.1 7.8e-12 45.5 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) Claudin_3 PF06653.11 EPS25958.1 - 0.047 13.6 0.9 1.9 8.4 0.1 2.3 2 0 0 2 2 2 0 Tight junction protein, Claudin-like zf-H2C2_2 PF13465.6 EPS25959.1 - 1.2e-13 50.8 17.3 2.9e-08 33.8 2.8 3.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.26 EPS25959.1 - 3.3e-10 39.8 22.3 0.00087 19.6 4.7 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPS25959.1 - 1.6e-06 28.4 19.9 0.021 15.6 3.7 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EPS25959.1 - 1.5e-05 24.8 17.2 0.014 15.4 0.1 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-Di19 PF05605.12 EPS25959.1 - 0.0016 18.7 7.6 0.0085 16.4 5.1 2.5 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook PF04423.14 EPS25959.1 - 0.0026 17.6 2.3 0.22 11.4 0.3 2.4 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-C2H2_jaz PF12171.8 EPS25959.1 - 0.011 16.0 6.5 0.4 11.0 1.2 3.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 EPS25959.1 - 0.011 15.9 7.5 0.019 15.0 2.2 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-C2HC_2 PF13913.6 EPS25959.1 - 0.033 14.1 0.8 0.033 14.1 0.8 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_9 PF16293.5 EPS25959.1 - 0.034 14.0 1.6 3 7.8 0.2 3.4 3 0 0 3 3 3 0 C2H2 type zinc-finger (1 copy) zf-C2HE PF16278.5 EPS25959.1 - 0.05 14.1 14.8 0.11 13.0 1.6 3.1 1 1 2 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger HypA PF01155.19 EPS25959.1 - 0.09 12.8 2.9 0.26 11.3 3.0 1.7 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 EPS25959.1 - 0.11 12.6 8.2 1.4 9.0 8.0 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-CHCC PF10276.9 EPS25959.1 - 0.22 11.6 7.5 5.5 7.1 0.2 3.5 4 0 0 4 4 4 0 Zinc-finger domain zinc_ribbon_9 PF14369.6 EPS25959.1 - 0.27 11.5 4.1 23 5.3 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon zf-ISL3 PF14690.6 EPS25959.1 - 1.1 10.0 10.0 3.1 8.6 0.5 3.3 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C2H2_2 PF12756.7 EPS25959.1 - 1.3 9.4 10.2 1.8 8.9 1.0 3.2 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) FYDLN_acid PF09538.10 EPS25959.1 - 1.4 9.6 12.0 0.57 10.9 1.2 3.5 2 1 1 3 3 3 0 Protein of unknown function (FYDLN_acid) zinc-ribbons_6 PF07191.12 EPS25959.1 - 2.1 8.4 5.4 9.5 6.3 5.4 2.0 1 1 0 1 1 1 0 zinc-ribbons zf_C2H2_ZHX PF18387.1 EPS25959.1 - 2.2 8.0 6.2 12 5.7 0.4 3.6 1 1 2 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-FPG_IleRS PF06827.14 EPS25959.1 - 2.7 7.9 7.3 2.1 8.3 0.6 2.9 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS FYVE PF01363.21 EPS25959.1 - 8.5 6.6 11.3 9 6.5 4.5 2.4 1 1 1 2 2 2 0 FYVE zinc finger GAGA PF09237.11 EPS25959.1 - 9.5 6.1 13.8 3.1 7.7 1.2 3.5 1 1 2 3 3 3 0 GAGA factor MARVEL PF01284.23 EPS25961.1 - 0.0014 18.7 8.2 0.0029 17.6 3.7 2.5 2 0 0 2 2 2 1 Membrane-associating domain FixQ PF05545.11 EPS25961.1 - 0.0025 17.7 2.9 1.1 9.2 0.3 2.6 2 0 0 2 2 2 2 Cbb3-type cytochrome oxidase component FixQ DUF4355 PF14265.6 EPS25961.1 - 0.049 13.9 0.0 0.079 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Cnd2 PF05786.14 EPS25962.1 - 0 1020.2 5.7 0 1020.0 5.7 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 EPS25962.1 - 0.046 13.9 0.8 0.12 12.6 0.0 2.1 2 0 0 2 2 2 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Na_Ca_ex PF01699.24 EPS25963.1 - 1.8e-50 170.8 48.4 6e-28 97.7 17.9 3.2 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Sugar_tr PF00083.24 EPS25964.1 - 5.3e-96 322.2 30.8 6.2e-96 322.0 30.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS25964.1 - 7.3e-24 84.3 38.9 1.3e-23 83.5 36.4 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EPS25964.1 - 0.00095 17.7 4.3 0.00095 17.7 4.3 2.0 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) EF-hand_4 PF12763.7 EPS25965.1 - 1.8e-24 85.6 0.0 9.6e-11 41.6 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand WH2 PF02205.20 EPS25965.1 - 4.2e-11 42.3 0.6 9e-11 41.2 0.6 1.6 1 0 0 1 1 1 1 WH2 motif DUF1720 PF08226.11 EPS25965.1 - 4.4e-06 27.0 104.0 0.00013 22.3 35.2 7.7 5 2 1 7 7 7 3 Domain of unknown function (DUF1720) EF-hand_1 PF00036.32 EPS25965.1 - 0.00045 19.6 0.1 1.6 8.4 0.0 3.5 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 EPS25965.1 - 0.01 16.2 0.0 0.01 16.2 0.0 3.6 4 0 0 4 4 4 0 EF-hand domain pair E3_binding PF02817.17 EPS25965.1 - 0.047 14.0 0.4 0.19 12.1 0.4 2.1 1 0 0 1 1 1 0 e3 binding domain MHB PF16525.5 EPS25965.1 - 0.14 12.5 0.1 0.14 12.5 0.1 2.6 2 0 0 2 2 2 0 Haemophore, haem-binding RNA_pol_L_2 PF13656.6 EPS25966.1 - 4.8e-26 90.3 0.0 7.4e-26 89.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EPS25966.1 - 4.4e-10 38.8 0.0 7.6e-10 38.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Noggin PF05806.12 EPS25967.1 - 0.075 12.9 4.4 0.16 11.8 4.4 1.5 1 0 0 1 1 1 0 Noggin CAMSAP_CC1 PF17095.5 EPS25967.1 - 0.51 10.2 5.2 1.3 8.9 5.2 1.6 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin PBP1_TM PF14812.6 EPS25967.1 - 2.1 8.7 14.5 9.8 6.6 6.7 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleo_P87 PF07267.11 EPS25967.1 - 3.3 6.5 11.9 0.8 8.5 8.0 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 PMT PF02366.18 EPS25969.1 - 2.1e-86 289.5 19.2 3.8e-86 288.7 19.2 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EPS25969.1 - 7e-68 228.2 0.8 7e-68 228.2 0.8 3.2 3 1 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EPS25969.1 - 7.8e-18 65.0 0.0 1.2e-17 64.4 0.0 1.2 1 0 0 1 1 1 1 MIR domain NAD_binding_4 PF07993.12 EPS25970.1 - 0.015 14.5 0.0 0.046 12.9 0.0 1.8 2 0 0 2 2 2 0 Male sterility protein Epimerase PF01370.21 EPS25970.1 - 0.026 14.0 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_24 PF13578.6 EPS25972.1 - 2.6e-12 47.7 0.0 4.1e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 EPS25972.1 - 8e-11 41.5 0.0 1.1e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Lyase_aromatic PF00221.19 EPS25973.1 - 7.6e-152 506.2 0.1 9.4e-152 505.9 0.1 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase FAD_binding_3 PF01494.19 EPS25974.1 - 1.4e-78 264.6 0.0 1.7e-78 264.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EPS25974.1 - 1.5e-38 132.4 0.0 3.2e-38 131.4 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.14 EPS25974.1 - 6.9e-05 21.7 0.3 9.9e-05 21.2 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 EPS25974.1 - 0.00012 21.3 0.3 0.00021 20.5 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EPS25974.1 - 0.00016 21.0 0.1 0.00025 20.4 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 EPS25974.1 - 0.004 16.5 0.1 0.006 15.9 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EPS25974.1 - 0.0089 15.4 0.5 0.013 14.8 0.5 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 EPS25974.1 - 0.026 14.1 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase SE PF08491.10 EPS25974.1 - 0.04 13.0 0.0 0.27 10.3 0.0 2.0 1 1 0 1 1 1 0 Squalene epoxidase NAD_binding_8 PF13450.6 EPS25974.1 - 0.1 12.8 0.1 0.23 11.7 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF4788 PF16032.5 EPS25974.1 - 0.19 10.7 0.0 0.42 9.5 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4788) Pyr_redox_2 PF07992.14 EPS25974.1 - 0.19 10.9 0.1 0.37 10.0 0.1 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SBF PF01758.16 EPS25975.1 - 2.2e-53 180.9 8.5 2.2e-53 180.9 8.5 2.2 2 1 1 3 3 3 1 Sodium Bile acid symporter family DUF4271 PF14093.6 EPS25975.1 - 0.037 14.0 16.9 0.99 9.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) DUF1673 PF07895.11 EPS25975.1 - 0.4 10.4 9.5 4 7.1 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) MFS_1 PF07690.16 EPS25977.1 - 5.7e-27 94.6 30.3 5.7e-27 94.6 30.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily WD40 PF00400.32 EPS25978.1 - 0.0039 18.0 10.4 2.4 9.2 0.1 5.2 6 1 0 6 6 6 2 WD domain, G-beta repeat ATP-synt_E PF05680.12 EPS25979.1 - 1.9e-24 85.8 0.6 2e-24 85.8 0.6 1.0 1 0 0 1 1 1 1 ATP synthase E chain Adhesin_P1_N PF18652.1 EPS25979.1 - 0.0081 16.1 3.4 0.015 15.3 2.9 1.7 2 0 0 2 2 2 1 Adhesin P1 N-terminal domain UCR_14kD PF02271.16 EPS25979.1 - 0.019 14.9 0.1 0.023 14.6 0.1 1.1 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit Chordopox_A13L PF05961.11 EPS25979.1 - 0.064 13.5 0.8 0.13 12.5 0.7 1.6 1 1 1 2 2 2 0 Chordopoxvirus A13L protein CSN8_PSD8_EIF3K PF10075.9 EPS25980.1 - 9.6e-31 106.7 0.0 1.3e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family STT3 PF02516.14 EPS25981.1 - 5.9e-145 483.9 36.1 4.2e-140 467.9 34.1 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Coiled-coil_56 PF09813.9 EPS25982.1 - 7.5e-05 22.7 0.0 8.3e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 DUF3453 PF11935.8 EPS25983.1 - 7.2e-72 241.7 0.6 1.9e-71 240.3 0.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) B56 PF01603.20 EPS25983.1 - 0.1 11.6 0.2 0.32 9.9 0.1 1.8 2 0 0 2 2 2 0 Protein phosphatase 2A regulatory B subunit (B56 family) Sds3 PF08598.11 EPS25984.1 - 5.9e-19 68.9 2.7 5.9e-19 68.9 2.7 2.0 2 1 0 2 2 2 1 Sds3-like DUF1487 PF07368.11 EPS25984.1 - 0.014 14.9 0.6 1 8.8 0.0 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1487) DUF5582 PF17819.1 EPS25984.1 - 0.063 13.7 4.2 1.9 8.9 0.6 2.6 1 1 1 2 2 2 0 Family of unknown function (DUF5582) RRM_1 PF00076.22 EPS25985.1 - 1.5e-05 24.7 1.5 0.027 14.3 0.0 3.7 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAD_binding_9 PF13454.6 EPS25987.1 - 7.1e-06 26.1 0.0 0.00023 21.2 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EPS25987.1 - 8.2e-06 25.3 0.0 1.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EPS25987.1 - 0.0039 16.4 0.0 0.029 13.5 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EPS25987.1 - 0.029 13.6 0.0 2.1 7.5 0.0 2.5 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GPI-anchored PF10342.9 EPS25989.1 - 6.1e-21 75.0 1.1 6.1e-21 75.0 1.1 2.4 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family RIFIN PF02009.16 EPS25989.1 - 0.7 9.7 2.5 0.7 9.7 2.5 1.1 1 0 0 1 1 1 0 Rifin SOG2 PF10428.9 EPS25989.1 - 0.98 8.5 18.6 1.3 8.1 18.6 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Hamartin PF04388.12 EPS25989.1 - 9 4.8 17.5 10 4.6 17.5 1.0 1 0 0 1 1 1 0 Hamartin protein NUFIP1 PF10453.9 EPS25990.1 - 5.7e-14 51.7 2.0 5.7e-14 51.7 2.0 3.1 3 0 0 3 3 3 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH_4 PF18044.1 EPS25990.1 - 4.2e-08 32.8 3.9 6.9e-08 32.1 3.9 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 EPS25990.1 - 6.8e-08 32.2 3.6 1.1e-07 31.5 3.6 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EPS25990.1 - 9.3e-05 22.4 6.6 0.00015 21.7 6.6 1.3 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 EPS25990.1 - 0.00067 20.3 2.8 0.0007 20.3 0.0 2.4 2 0 0 2 2 2 1 Torus domain zf-CCCH_2 PF14608.6 EPS25990.1 - 0.081 13.4 4.8 0.18 12.3 4.8 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger RNA_pol_Rbc25 PF08292.12 EPS25991.1 - 7.1e-34 116.8 0.6 2.9e-33 114.8 0.6 1.8 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 EPS25991.1 - 3.1e-14 53.1 0.0 4.7e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Cys_Met_Meta_PP PF01053.20 EPS25992.1 - 6.6e-138 459.4 0.0 7.4e-138 459.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EPS25992.1 - 4.8e-09 35.9 0.1 6.4e-09 35.5 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EPS25992.1 - 7.9e-08 32.0 0.3 1.3e-07 31.2 0.3 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EPS25992.1 - 2.3e-06 26.8 0.7 3.7e-06 26.2 0.2 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EPS25992.1 - 0.0031 16.8 0.2 0.0057 16.0 0.2 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase MFS_1 PF07690.16 EPS25994.1 - 3.4e-12 46.0 47.1 1.1e-10 41.0 32.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.15 EPS25994.1 - 0.0035 16.4 4.6 0.0035 16.4 4.6 2.3 2 0 0 2 2 2 1 PUCC protein NmrA PF05368.13 EPS25995.1 - 1.3e-06 28.2 0.0 4.9e-06 26.3 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPS25995.1 - 0.029 14.3 0.0 0.049 13.5 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding S-antigen PF05756.11 EPS25995.1 - 0.11 12.9 0.2 22 5.5 0.0 2.3 2 0 0 2 2 2 0 S-antigen protein p450 PF00067.22 EPS25996.1 - 7.7e-52 176.6 0.0 1.1e-51 176.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ERG4_ERG24 PF01222.17 EPS25997.1 - 2e-137 458.5 16.1 2.3e-137 458.3 16.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF3584 PF12128.8 EPS26000.1 - 2.7e-05 22.0 70.1 0.0085 13.7 46.4 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3584) Filament PF00038.21 EPS26000.1 - 0.029 13.9 67.7 0.013 15.1 43.1 3.2 1 1 1 2 2 2 0 Intermediate filament protein TPR_MLP1_2 PF07926.12 EPS26000.1 - 2.1 8.4 81.7 0.35 10.9 22.3 5.6 1 1 4 5 5 5 0 TPR/MLP1/MLP2-like protein CEP63 PF17045.5 EPS26000.1 - 4.4 7.1 65.4 0.75 9.6 10.2 3.6 1 1 2 3 3 3 0 Centrosomal protein of 63 kDa FOXP-CC PF16159.5 EPS26001.1 - 1.2 9.8 11.3 0.074 13.7 1.3 3.0 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 EPS26002.1 - 0.27 11.6 10.9 0.51 10.7 0.2 3.8 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 EPS26002.1 - 0.98 10.1 13.0 5.2 7.8 0.0 4.5 4 0 0 4 4 4 0 FOXP coiled-coil domain KRBA1 PF15287.6 EPS26002.1 - 1.7 8.4 5.2 1.1 9.1 1.6 2.6 2 0 0 2 2 2 0 KRBA1 family repeat zf-C2H2 PF00096.26 EPS26002.1 - 3.1 8.4 37.4 1.6 9.3 4.8 6.9 6 0 0 6 6 6 0 Zinc finger, C2H2 type DUF2681 PF10883.8 EPS26003.1 - 0.03 14.7 0.2 0.051 14.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) AAA PF00004.29 EPS26005.1 - 1e-48 165.1 0.0 6.2e-42 143.2 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EPS26005.1 - 6.5e-09 35.5 0.0 2.4e-08 33.7 0.0 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EPS26005.1 - 2e-08 34.8 0.5 2.2e-05 24.9 0.0 4.1 3 0 0 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.17 EPS26005.1 - 6.9e-08 32.4 0.0 2.8e-06 27.2 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 EPS26005.1 - 5.1e-06 26.7 0.0 1.4e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EPS26005.1 - 0.00011 22.3 0.0 0.0013 18.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EPS26005.1 - 0.00027 21.2 0.7 0.018 15.3 0.1 3.7 2 2 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 EPS26005.1 - 0.00076 19.6 0.0 1.3 9.1 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain Bromodomain PF00439.25 EPS26005.1 - 0.00097 19.2 0.0 0.0024 17.9 0.0 1.6 1 0 0 1 1 1 1 Bromodomain RNA_helicase PF00910.22 EPS26005.1 - 0.004 17.5 0.0 0.014 15.8 0.0 2.0 1 0 0 1 1 1 1 RNA helicase AAA_30 PF13604.6 EPS26005.1 - 0.0046 16.7 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EPS26005.1 - 0.0081 16.3 0.0 0.039 14.1 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.6 EPS26005.1 - 0.0093 15.6 0.0 0.043 13.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EPS26005.1 - 0.0095 16.0 0.0 0.028 14.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EPS26005.1 - 0.0096 15.7 0.0 0.06 13.1 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EPS26005.1 - 0.016 15.8 0.0 0.1 13.2 0.0 2.5 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 EPS26005.1 - 0.018 15.0 0.0 0.41 10.6 0.0 2.5 2 0 0 2 2 2 0 NACHT domain Mg_chelatase PF01078.21 EPS26005.1 - 0.018 14.5 0.1 0.11 11.9 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 EPS26005.1 - 0.018 14.2 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain ABC_tran PF00005.27 EPS26005.1 - 0.03 14.8 0.0 0.16 12.5 0.0 2.3 1 0 0 1 1 1 0 ABC transporter Parvo_NS1 PF01057.17 EPS26005.1 - 0.038 13.1 0.0 0.26 10.4 0.0 2.0 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.6 EPS26005.1 - 0.046 14.0 0.7 0.17 12.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EPS26005.1 - 0.052 13.3 0.0 1.7 8.3 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_3 PF07726.11 EPS26005.1 - 0.075 12.9 0.0 0.21 11.4 0.0 1.7 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 EPS26005.1 - 0.14 11.4 0.0 0.34 10.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 EPS26005.1 - 0.15 11.5 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Torsin PF06309.11 EPS26005.1 - 0.18 11.9 0.0 0.66 10.1 0.0 1.9 2 0 0 2 2 1 0 Torsin AAA_11 PF13086.6 EPS26005.1 - 0.43 10.3 0.0 0.43 10.3 0.0 3.2 4 0 0 4 4 3 0 AAA domain Sec66 PF09802.9 EPS26006.1 - 4.7e-82 273.9 0.3 5.6e-82 273.7 0.3 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF3848 PF12959.7 EPS26006.1 - 0.024 14.7 0.1 0.058 13.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3848) TPPII_N PF12583.8 EPS26006.1 - 2.9 8.5 12.8 5.3 7.6 12.8 1.3 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal PPR_2 PF13041.6 EPS26007.1 - 2.2e-05 24.6 0.4 1.8 8.8 0.1 4.2 4 0 0 4 4 4 3 PPR repeat family TPR_4 PF07721.14 EPS26007.1 - 0.26 12.0 1.7 36 5.4 0.3 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat ORC3_N PF07034.11 EPS26008.1 - 3.3e-32 111.9 0.0 2.5e-30 105.7 0.0 2.4 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 EPS26008.1 - 1.3e-25 90.1 0.1 1e-15 58.0 0.0 2.4 1 1 1 2 2 2 2 Origin recognition complex winged helix C-terminal HEAT_2 PF13646.6 EPS26009.1 - 0.0016 18.8 0.6 0.011 16.1 0.4 2.3 1 1 1 2 2 2 1 HEAT repeats HEAT PF02985.22 EPS26009.1 - 0.0053 16.9 0.8 1.4 9.3 0.0 3.1 3 0 0 3 3 3 1 HEAT repeat Na_trans_assoc PF06512.13 EPS26009.1 - 0.012 15.9 0.0 0.021 15.1 0.0 1.4 1 1 0 1 1 1 0 Sodium ion transport-associated CDC45 PF02724.14 EPS26009.1 - 0.024 13.0 1.5 0.035 12.4 1.5 1.2 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 EPS26009.1 - 0.7 9.3 8.0 1.2 8.5 8.0 1.4 1 0 0 1 1 1 0 SDA1 COPI_C PF06957.11 EPS26009.1 - 9 4.9 7.2 13 4.4 7.2 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Nop14 PF04147.12 EPS26010.1 - 9.4e-292 970.4 36.9 1.1e-291 970.1 36.9 1.1 1 0 0 1 1 1 1 Nop14-like family Noc2 PF03715.13 EPS26010.1 - 0.0017 17.7 0.0 0.0039 16.5 0.0 1.7 1 0 0 1 1 1 1 Noc2p family Sulfotransfer_1 PF00685.27 EPS26011.1 - 0.00054 19.5 0.0 0.0052 16.3 0.0 2.2 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EPS26011.1 - 0.03 14.7 0.0 0.088 13.2 0.0 1.8 2 1 0 2 2 2 0 Sulfotransferase family Ank_2 PF12796.7 EPS26012.1 - 7e-37 125.9 0.0 8.3e-14 51.9 0.0 3.8 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EPS26012.1 - 1.4e-32 108.1 1.5 0.00082 19.6 0.0 8.4 8 0 0 8 8 8 8 Ankyrin repeat Ank_5 PF13857.6 EPS26012.1 - 2.3e-32 110.6 3.2 1e-09 38.4 0.1 6.9 3 3 4 7 7 7 6 Ankyrin repeats (many copies) Ank_4 PF13637.6 EPS26012.1 - 8.5e-30 102.8 0.9 2.3e-11 43.9 0.0 5.1 2 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 EPS26012.1 - 1.5e-28 98.0 8.7 0.001 19.4 0.0 8.2 8 0 0 8 8 8 7 Ankyrin repeat COesterase PF00135.28 EPS26013.1 - 6e-92 309.1 0.0 7.4e-92 308.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EPS26013.1 - 2.2e-10 40.7 0.0 9.2e-10 38.7 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EPS26013.1 - 0.001 18.6 0.2 0.002 17.6 0.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF4187 PF13821.6 EPS26014.1 - 1.8e-21 75.7 2.3 3.8e-21 74.6 2.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.23 EPS26014.1 - 1.9e-08 34.0 0.4 1.4e-06 28.1 0.1 2.5 2 0 0 2 2 2 1 G-patch domain DUF4615 PF15393.6 EPS26014.1 - 0.69 10.5 11.7 0.34 11.5 5.7 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4615) MRP-S31 PF15433.6 EPS26014.1 - 4.4 6.9 12.9 0.18 11.5 4.1 2.1 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 FAR1 PF03101.15 EPS26016.1 - 0.034 14.8 0.3 0.045 14.5 0.3 1.2 1 0 0 1 1 1 0 FAR1 DNA-binding domain Fimbrial_PilY2 PF14481.6 EPS26016.1 - 0.072 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Type 4 fimbrial biogenesis protein PilY2 DbpA PF03880.15 EPS26017.1 - 0.018 15.1 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 DbpA RNA binding domain zf-AN1 PF01428.16 EPS26017.1 - 0.056 13.6 0.3 0.11 12.7 0.3 1.3 1 0 0 1 1 1 0 AN1-like Zinc finger DUF4749 PF15936.5 EPS26018.1 - 0.17 13.0 6.4 0.91 10.7 1.0 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4749) Peptidase_S49_N PF08496.10 EPS26018.1 - 1 9.4 9.6 3.9 7.5 4.5 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF3395 PF11875.8 EPS26018.1 - 2 8.3 8.5 0.59 10.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3395) MFS_1 PF07690.16 EPS26019.1 - 7.5e-30 104.0 35.8 6.3e-27 94.4 23.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS26019.1 - 6.6e-09 35.1 3.9 6.6e-09 35.1 3.9 2.0 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 EPS26019.1 - 0.00037 19.0 3.3 0.036 12.5 2.2 2.6 1 1 1 2 2 2 2 Transmembrane secretion effector MFS_1_like PF12832.7 EPS26019.1 - 1.4 7.6 13.7 0.0085 15.0 3.7 2.1 2 0 0 2 2 2 0 MFS_1 like family Fungal_TACC PF12709.7 EPS26020.1 - 3e-11 43.6 21.4 1.4e-09 38.3 4.2 4.1 4 1 1 5 5 5 2 Fungal Transforming acidic coiled-coil (TACC) proteins THOC7 PF05615.13 EPS26020.1 - 0.04 14.2 24.5 0.42 10.9 12.0 3.1 2 1 0 2 2 2 0 Tho complex subunit 7 Tropomyosin_1 PF12718.7 EPS26020.1 - 2.8 8.1 39.8 8.7 6.5 5.4 3.7 2 1 1 3 3 3 0 Tropomyosin like Z1 PF10593.9 EPS26020.1 - 4.8 6.6 7.1 11 5.4 0.3 2.4 2 0 0 2 2 2 0 Z1 domain DUF1664 PF07889.12 EPS26020.1 - 5.8 7.0 14.6 2.1 8.4 2.4 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 EPS26020.1 - 8.1 5.7 33.4 1.4 8.2 12.4 3.1 2 1 1 4 4 4 0 Domain of unknown function (DUF4407) AbfS_sensor PF18225.1 EPS26022.1 - 0.00031 20.6 0.0 0.091 12.7 0.0 2.4 2 0 0 2 2 2 2 Sensor histidine kinase (AbfS) sensor domain Fungal_trans PF04082.18 EPS26023.1 - 5.6e-31 107.5 1.1 9.1e-31 106.9 1.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS26023.1 - 0.00088 19.4 17.6 0.0018 18.3 17.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain T5orf172 PF10544.9 EPS26025.1 - 5.2e-11 43.0 0.0 1.5e-10 41.5 0.0 1.8 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 EPS26025.1 - 0.0039 17.8 0.5 0.0092 16.6 0.5 1.6 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 ORC6 PF05460.13 EPS26025.1 - 2.4 7.3 12.1 3.5 6.8 12.1 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF480 PF04337.12 EPS26026.1 - 0.0097 16.0 0.0 0.011 15.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF480 Peptidase_S10 PF00450.22 EPS26027.1 - 8.4e-110 368.0 3.2 9.9e-110 367.8 3.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase MFS_1 PF07690.16 EPS26028.1 - 1.5e-18 66.9 30.4 2.1e-18 66.4 30.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 EPS26028.1 - 1.6e-10 41.0 4.7 1.6e-10 41.0 4.7 2.0 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1_like PF12832.7 EPS26028.1 - 0.0013 17.6 6.6 0.0013 17.6 6.6 2.4 1 1 1 2 2 2 1 MFS_1 like family DUF2730 PF10805.8 EPS26028.1 - 0.22 11.6 0.0 0.46 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Amidohydro_1 PF01979.20 EPS26029.1 - 1.1e-18 67.6 0.0 1.6e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EPS26029.1 - 2.7e-09 37.0 0.7 1.8e-06 27.7 0.1 2.2 2 0 0 2 2 2 2 Amidohydrolase family GMC_oxred_N PF00732.19 EPS26030.1 - 5.5e-54 183.5 0.0 6.9e-54 183.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EPS26030.1 - 9.4e-38 130.0 0.0 1.6e-37 129.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EPS26030.1 - 3.3e-08 33.0 0.1 0.004 16.3 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 EPS26030.1 - 0.00023 20.4 0.0 0.00034 19.8 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EPS26030.1 - 0.00033 20.8 0.1 0.00099 19.3 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EPS26030.1 - 0.00047 19.8 0.1 0.033 13.8 0.1 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EPS26030.1 - 0.001 18.5 0.4 0.055 12.8 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPS26030.1 - 0.0029 16.9 0.0 0.014 14.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPS26030.1 - 0.031 14.8 0.4 2.4 8.8 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EPS26030.1 - 0.073 12.3 0.0 0.76 9.0 0.0 2.4 3 0 0 3 3 3 0 Thi4 family GIDA PF01134.22 EPS26030.1 - 0.082 12.0 0.3 0.85 8.6 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Aldedh PF00171.22 EPS26032.1 - 1.3e-155 518.5 0.1 1.4e-155 518.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glucosamine_iso PF01182.20 EPS26033.1 - 6.6e-20 71.9 0.0 1.1e-19 71.3 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Glyco_hydro_3 PF00933.21 EPS26034.1 - 9.4e-65 219.1 0.0 1.4e-64 218.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 EPS26034.1 - 1.2e-05 25.3 0.2 3.7e-05 23.8 0.2 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_1 PF00583.25 EPS26034.1 - 0.0006 20.0 0.0 0.0018 18.5 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_6 PF13480.7 EPS26034.1 - 0.038 14.1 0.0 0.22 11.7 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain SMODS PF18144.1 EPS26034.1 - 0.043 14.0 0.0 0.082 13.1 0.0 1.3 1 0 0 1 1 1 0 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain NDT80_PhoG PF05224.12 EPS26037.1 - 1.1e-38 133.3 0.0 2.1e-38 132.4 0.0 1.5 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family CPSF_A PF03178.15 EPS26038.1 - 8.6e-109 363.7 0.0 3.5e-108 361.7 0.0 2.1 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 EPS26038.1 - 6.6e-21 74.5 0.0 6.2e-20 71.3 0.0 2.1 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term LMBR1 PF04791.16 EPS26039.1 - 7.9e-18 64.6 25.4 6e-16 58.5 19.3 2.4 2 1 0 2 2 2 1 LMBR1-like membrane protein Atg14 PF10186.9 EPS26041.1 - 2.2e-92 309.6 1.9 3e-92 309.1 1.9 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 FAM76 PF16046.5 EPS26041.1 - 4.2 6.7 6.8 8.7 5.6 6.8 1.5 1 0 0 1 1 1 0 FAM76 protein Zip PF02535.22 EPS26042.1 - 2.3e-48 165.1 0.8 2.9e-48 164.8 0.8 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter TRAPPC9-Trs120 PF08626.11 EPS26042.1 - 0.18 9.2 0.0 0.22 8.8 0.0 1.0 1 0 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Thiolase_N PF00108.23 EPS26043.1 - 5.5e-92 307.8 0.7 5.5e-92 307.8 0.7 1.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EPS26043.1 - 3.5e-44 149.4 1.8 3.5e-44 149.4 1.8 2.0 2 1 1 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EPS26043.1 - 2.5e-06 27.3 2.5 6.2e-06 26.0 1.3 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EPS26043.1 - 0.014 15.2 3.0 0.32 10.9 0.1 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GTP_EFTU PF00009.27 EPS26044.1 - 2.1e-48 164.5 0.0 4.9e-48 163.2 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 EPS26044.1 - 9e-38 129.6 12.7 1.6e-37 128.8 12.7 1.4 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 EPS26044.1 - 6.2e-24 84.1 0.0 1.5e-23 82.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 EPS26044.1 - 9.2e-21 73.7 0.0 2.7e-20 72.2 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EPS26044.1 - 1.3e-09 38.3 0.0 3.4e-09 37.0 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EPS26044.1 - 1.5e-07 31.4 0.2 1.6e-06 28.1 0.0 2.3 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EPS26044.1 - 4.6e-06 26.7 0.1 9.5e-06 25.7 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 EPS26044.1 - 0.018 14.6 0.0 0.086 12.4 0.0 2.0 2 0 0 2 2 2 0 Ras family SRPRB PF09439.10 EPS26044.1 - 0.17 11.3 0.2 1.6 8.1 0.1 2.5 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit FeS_assembly_P PF01883.19 EPS26045.1 - 3.6e-10 39.9 0.0 8.5e-10 38.7 0.0 1.7 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein Zn_clus PF00172.18 EPS26047.1 - 3.4e-06 27.1 8.5 6.3e-06 26.2 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPS26047.1 - 1.8e-05 24.0 0.0 3.3e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ANAPC_CDC26 PF10471.9 EPS26048.1 - 1.8e-11 44.7 0.0 1.1e-10 42.1 0.0 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 PBP1_TM PF14812.6 EPS26049.1 - 0.045 14.1 3.9 0.11 12.9 3.9 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RRF PF01765.19 EPS26050.1 - 5.6e-46 156.5 0.9 7.4e-46 156.1 0.9 1.1 1 0 0 1 1 1 1 Ribosome recycling factor PcfJ PF14284.6 EPS26050.1 - 0.089 12.7 0.7 0.2 11.6 0.7 1.6 1 0 0 1 1 1 0 PcfJ-like protein DUF1180 PF06679.12 EPS26050.1 - 0.42 11.0 3.8 0.23 11.9 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) HSP70 PF00012.20 EPS26051.1 - 1.7e-226 753.1 8.1 1.8e-226 753.0 8.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EPS26051.1 - 2.8e-17 62.5 0.2 2.1e-16 59.7 0.1 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EPS26051.1 - 0.00017 21.4 0.0 0.00037 20.3 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Bromodomain PF00439.25 EPS26052.1 - 9.9e-14 51.2 0.0 1.9e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Bromodomain DUF2218 PF09981.9 EPS26052.1 - 0.078 13.4 0.0 0.24 11.8 0.0 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2218) CKS PF01111.19 EPS26053.1 - 8.5e-35 118.8 0.5 8.5e-35 118.8 0.5 1.6 2 0 0 2 2 2 1 Cyclin-dependent kinase regulatory subunit Thioredoxin_4 PF13462.6 EPS26054.1 - 3.7e-11 43.5 0.0 7.7e-11 42.4 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.20 EPS26054.1 - 0.016 15.0 2.4 0.87 9.3 0.3 2.7 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Phage_TAC_6 PF09550.10 EPS26054.1 - 0.11 12.9 0.1 0.2 12.1 0.1 1.4 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC DUF3844 PF12955.7 EPS26056.1 - 2e-36 124.3 3.1 3.4e-36 123.6 3.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) zf-RING_2 PF13639.6 EPS26057.1 - 5.2e-12 45.9 6.9 7.9e-12 45.3 6.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EPS26057.1 - 1.3e-08 34.5 6.0 2.1e-08 33.9 6.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EPS26057.1 - 1.7e-08 34.1 1.9 2.7e-08 33.4 1.9 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 EPS26057.1 - 5e-08 32.7 4.4 8.1e-08 32.0 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EPS26057.1 - 3.7e-06 26.8 3.6 5.8e-06 26.2 3.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EPS26057.1 - 8.1e-06 26.0 10.2 3.3e-05 24.1 10.2 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EPS26057.1 - 0.00022 21.2 1.1 0.00022 21.2 1.1 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EPS26057.1 - 0.0019 18.0 2.8 0.0031 17.4 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EPS26057.1 - 0.0031 17.5 3.1 0.0079 16.2 3.1 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EPS26057.1 - 0.011 15.3 3.4 0.019 14.6 3.4 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 EPS26057.1 - 0.091 12.6 6.6 0.16 11.8 6.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 EPS26057.1 - 0.11 12.4 5.7 0.23 11.4 5.7 1.6 1 0 0 1 1 1 0 PHD-finger OAD_gamma PF04277.13 EPS26057.1 - 0.12 12.9 0.0 0.72 10.5 0.0 2.2 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain zf-C3HC4_4 PF15227.6 EPS26057.1 - 0.23 11.7 5.0 0.46 10.7 5.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EPS26057.1 - 0.53 10.2 6.5 1.4 8.8 6.5 1.7 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 EPS26057.1 - 0.58 10.4 3.5 1.6 9.0 3.5 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 EPS26057.1 - 0.64 10.2 4.1 1.3 9.2 4.1 1.6 1 1 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 EPS26057.1 - 0.79 9.8 4.2 2 8.5 4.2 1.7 1 1 0 1 1 1 0 Zinc-finger zf-RING-like PF08746.11 EPS26057.1 - 2.6 8.4 5.1 5.6 7.4 5.1 1.6 1 0 0 1 1 1 0 RING-like domain Prok-RING_1 PF14446.6 EPS26057.1 - 6.7 6.7 8.9 0.19 11.7 1.4 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Pro_isomerase PF00160.21 EPS26058.1 - 1.4e-49 168.4 0.8 1.6e-49 168.2 0.8 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD tRNA-synt_2c PF01411.19 EPS26059.1 - 8.5e-222 737.5 0.1 1.1e-221 737.1 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 EPS26059.1 - 1.5e-16 60.2 0.9 3.3e-16 59.1 0.9 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 EPS26059.1 - 4.5e-10 40.1 0.7 4.5e-10 40.1 0.7 2.2 2 0 0 2 2 2 1 DHHA1 domain Mucin PF01456.17 EPS26060.1 - 0.011 15.7 6.8 0.011 15.7 6.8 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein YpjP PF14005.6 EPS26062.1 - 0.0075 16.3 2.4 0.0091 16.0 2.4 1.2 1 0 0 1 1 1 1 YpjP-like protein Mor PF08765.11 EPS26062.1 - 0.032 14.2 1.0 0.39 10.7 0.9 2.2 1 1 0 1 1 1 0 Mor transcription activator family DUF4058 PF13267.6 EPS26062.1 - 0.56 9.6 3.3 0.66 9.3 3.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4058) Phostensin_N PF13916.6 EPS26063.1 - 0.02 15.2 2.0 0.38 11.1 1.9 2.3 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal DUF2268 PF10026.9 EPS26063.1 - 0.062 12.9 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) Mt_ATP-synt_B PF05405.14 EPS26063.1 - 0.28 10.8 5.7 0.65 9.6 5.7 1.6 1 0 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF3425 PF11905.8 EPS26065.1 - 1.7e-11 44.2 0.0 3.1e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) MGDG_synth PF06925.11 EPS26065.1 - 0.18 11.9 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Monogalactosyldiacylglycerol (MGDG) synthase NmrA PF05368.13 EPS26066.1 - 2.1e-37 128.9 0.0 2.8e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPS26066.1 - 4.5e-09 36.5 0.0 7e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EPS26066.1 - 0.00014 21.4 0.0 0.0002 20.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Mito_carr PF00153.27 EPS26067.1 - 7.2e-68 224.6 4.9 5e-22 77.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tom7 PF08038.12 EPS26068.1 - 2.7e-22 78.1 0.3 3.1e-22 77.9 0.3 1.1 1 0 0 1 1 1 1 TOM7 family RRM_1 PF00076.22 EPS26069.1 - 8.8e-35 118.4 0.0 3.9e-16 58.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EPS26069.1 - 0.00018 21.1 0.0 0.1 12.2 0.0 2.3 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 EPS26069.1 - 0.0032 17.1 0.1 0.37 10.5 0.1 2.4 2 0 0 2 2 2 2 Ribonuclease B OB domain RRM_7 PF16367.5 EPS26069.1 - 0.0077 16.3 0.0 0.025 14.7 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif DUF2015 PF09435.10 EPS26070.1 - 1.6e-47 160.0 0.0 1.8e-47 159.8 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Ribosomal_L28e PF01778.17 EPS26071.1 - 1.3e-34 119.4 0.6 1.6e-34 119.1 0.6 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Ldh_1_N PF00056.23 EPS26072.1 - 2.4e-46 157.3 0.0 3.3e-46 156.9 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 EPS26072.1 - 9.1e-45 152.6 0.0 1.3e-44 152.1 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.19 EPS26072.1 - 0.00031 19.8 0.0 0.00045 19.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.16 EPS26072.1 - 0.0029 17.2 0.1 0.36 10.4 0.0 2.3 1 1 1 2 2 2 2 Family 4 glycosyl hydrolase THF_DHG_CYH_C PF02882.19 EPS26072.1 - 0.055 12.8 0.3 0.68 9.2 0.1 2.5 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TRAPP PF04051.16 EPS26073.1 - 2.9e-47 160.1 0.0 3.4e-47 159.8 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PorB PF11565.8 EPS26073.1 - 0.07 13.5 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Alpha helical Porin B PINIT PF14324.6 EPS26074.1 - 8.9e-39 133.1 0.6 1.5e-38 132.4 0.6 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 EPS26074.1 - 2.6e-22 78.3 6.8 4.5e-22 77.5 6.8 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.27 EPS26074.1 - 4.2e-11 42.3 0.3 3.7e-10 39.3 0.1 2.3 2 0 0 2 2 2 1 SAP domain zf-Nse PF11789.8 EPS26074.1 - 4.8e-07 29.5 2.8 1.1e-06 28.4 2.8 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 EPS26074.1 - 0.12 12.3 4.0 0.26 11.2 4.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF2423 PF10338.9 EPS26075.1 - 6.6e-21 74.3 2.0 1.8e-20 72.9 2.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) Phosphodiest PF01663.22 EPS26076.1 - 6.4e-13 49.0 2.8 5.1e-07 29.6 0.3 2.2 1 1 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EPS26076.1 - 2.5e-05 23.8 0.1 0.0017 17.8 0.0 2.4 3 0 0 3 3 3 2 Sulfatase SpoVAC_SpoVAEB PF03862.13 EPS26076.1 - 0.11 12.7 0.1 0.11 12.7 0.1 2.2 2 0 0 2 2 2 0 SpoVAC/SpoVAEB sporulation membrane protein DUF229 PF02995.17 EPS26076.1 - 0.15 10.6 0.0 0.23 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Ribosomal_60s PF00428.19 EPS26077.1 - 0.041 14.5 2.5 0.082 13.5 2.5 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF3787 PF12655.7 EPS26078.1 - 0.0024 17.8 5.8 0.0032 17.4 0.4 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3787) Sec15 PF04091.12 EPS26079.1 - 5.1e-109 364.5 1.8 1e-108 363.5 1.8 1.5 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like Sec8_exocyst PF04048.14 EPS26079.1 - 0.00011 22.1 1.2 0.00011 22.1 1.2 3.1 3 1 0 3 3 3 1 Sec8 exocyst complex component specific domain COG2 PF06148.11 EPS26079.1 - 0.00019 21.5 2.5 0.00019 21.5 2.5 2.9 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.9 EPS26079.1 - 0.00031 20.9 6.6 0.0011 19.1 4.0 2.8 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Vps51 PF08700.11 EPS26079.1 - 0.014 15.5 1.2 0.083 13.0 0.2 2.7 2 0 0 2 2 2 0 Vps51/Vps67 DUF3510 PF12022.8 EPS26079.1 - 0.029 14.7 2.3 8.8 6.7 0.0 3.6 2 2 1 4 4 4 0 Domain of unknown function (DUF3510) Sec5 PF15469.6 EPS26079.1 - 0.05 13.4 7.3 0.063 13.1 1.0 3.2 4 0 0 4 4 4 0 Exocyst complex component Sec5 DUF717 PF05338.12 EPS26079.1 - 0.089 12.9 0.6 12 6.1 0.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF717) TSC22 PF01166.18 EPS26079.1 - 0.095 13.0 1.7 3.7 7.9 0.3 3.8 3 0 0 3 3 3 0 TSC-22/dip/bun family Vps54_N PF10475.9 EPS26079.1 - 0.25 10.6 9.8 0.041 13.2 3.8 2.1 2 0 0 2 2 2 0 Vacuolar-sorting protein 54, of GARP complex RAC_head PF16717.5 EPS26079.1 - 1.1 10.3 0.0 1.1 10.3 0.0 3.5 4 0 0 4 4 3 0 Ribosome-associated complex head domain CBFD_NFYB_HMF PF00808.23 EPS26080.1 - 6.7e-19 67.9 0.6 1.1e-18 67.2 0.6 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EPS26080.1 - 8.3e-16 58.5 0.1 1.6e-15 57.7 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 EPS26080.1 - 0.045 14.1 0.0 0.087 13.1 0.0 1.5 1 1 0 1 1 1 0 CENP-S associating Centromere protein X Etmic-2 PF06670.11 EPS26080.1 - 0.1 11.5 0.1 0.15 10.9 0.1 1.2 1 0 0 1 1 1 0 Microneme protein Etmic-2 Fcf2 PF08698.11 EPS26081.1 - 3.4e-38 129.9 0.4 3.4e-38 129.9 0.4 1.9 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing PNP_UDP_1 PF01048.20 EPS26082.1 - 5e-54 183.0 0.2 7.1e-54 182.5 0.2 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily Ribosomal_S10 PF00338.22 EPS26083.1 - 2.1e-28 98.4 0.0 3.3e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e tRNA-synt_1b PF00579.25 EPS26084.1 - 2.5e-76 256.8 0.0 3.1e-76 256.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF883 PF05957.13 EPS26084.1 - 0.022 15.3 1.0 0.056 14.0 1.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Asp PF00026.23 EPS26085.1 - 1.4e-71 241.5 0.5 1.7e-71 241.2 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EPS26085.1 - 1.2e-14 55.0 2.0 1.2e-13 51.7 1.2 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EPS26085.1 - 4.2e-09 36.9 0.7 0.062 14.0 0.1 4.2 3 1 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 EPS26085.1 - 9.5e-07 29.3 0.0 0.11 13.1 0.0 3.4 3 1 0 3 3 3 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 EPS26085.1 - 0.069 12.9 0.0 0.44 10.3 0.0 2.2 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal Methyltransf_31 PF13847.6 EPS26086.1 - 2.8e-06 27.2 0.0 5.5e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPS26086.1 - 1.8e-05 25.4 0.0 5.6e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PrmC_N PF17827.1 EPS26086.1 - 0.00015 22.3 0.0 0.00047 20.7 0.0 2.0 1 1 0 1 1 1 1 PrmC N-terminal domain Methyltransf_23 PF13489.6 EPS26086.1 - 0.00024 21.0 0.0 0.00043 20.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EPS26086.1 - 0.00049 19.7 0.0 0.061 12.9 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase small domain N6_Mtase PF02384.16 EPS26086.1 - 0.002 17.4 0.0 0.41 9.9 0.0 2.2 2 0 0 2 2 2 2 N-6 DNA Methylase PrmA PF06325.13 EPS26086.1 - 0.0065 15.9 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EPS26086.1 - 0.021 15.5 0.0 0.051 14.2 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EPS26086.1 - 0.074 13.8 0.0 0.18 12.6 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain FA_hydroxylase PF04116.13 EPS26087.1 - 8.3e-25 87.7 16.8 8.3e-25 87.7 16.8 2.2 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily WD40 PF00400.32 EPS26088.1 - 2.8e-62 205.2 11.2 1.9e-09 38.0 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS26088.1 - 2e-20 72.9 0.1 0.00061 20.0 0.0 6.5 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Tup_N PF08581.10 EPS26088.1 - 2.6e-18 66.1 10.6 4.5e-18 65.3 10.6 1.4 1 0 0 1 1 1 1 Tup N-terminal WD40_like PF17005.5 EPS26088.1 - 8.9e-08 31.8 0.0 0.088 12.1 0.0 4.5 3 1 2 5 5 5 3 WD40-like domain Ge1_WD40 PF16529.5 EPS26088.1 - 2.8e-06 26.5 0.1 0.62 9.0 0.0 4.7 1 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 EPS26088.1 - 3.5e-05 22.5 0.3 0.00062 18.4 0.2 2.5 1 1 1 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.8 EPS26088.1 - 6e-05 21.9 0.1 0.28 9.8 0.0 3.2 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 EPS26088.1 - 0.021 14.2 0.1 7 5.9 0.0 2.8 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal DUF853 PF05872.12 EPS26088.1 - 0.13 10.8 0.6 0.18 10.4 0.6 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) TPX2 PF06886.11 EPS26088.1 - 2.8 8.2 5.7 5.7 7.3 5.7 1.5 1 1 0 1 1 1 0 Targeting protein for Xklp2 (TPX2) zf-H2C2_2 PF13465.6 EPS26089.1 - 6.3e-14 51.7 26.3 4.1e-09 36.5 1.6 4.9 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.26 EPS26089.1 - 9.9e-14 50.9 35.0 0.00086 19.6 0.5 5.2 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPS26089.1 - 1.7e-09 37.7 21.4 0.012 16.4 0.3 5.0 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.7 EPS26089.1 - 0.0015 18.9 5.3 0.044 14.2 0.1 4.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 EPS26089.1 - 0.0019 18.5 3.4 0.0019 18.5 3.4 4.1 2 1 2 4 4 4 1 C2H2-type zinc ribbon zf-C2H2_aberr PF17017.5 EPS26089.1 - 0.012 15.8 3.6 1.4 9.0 0.0 3.2 2 1 1 3 3 3 0 Aberrant zinc-finger zf-DNA_Pol PF08996.10 EPS26089.1 - 1.7 8.4 6.8 6.7 6.4 1.0 2.3 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger ADK_lid PF05191.14 EPS26089.1 - 9.3 6.3 6.2 17 5.5 3.3 2.7 2 1 0 2 2 2 0 Adenylate kinase, active site lid MIF4G_like PF09088.11 EPS26090.1 - 3.4e-90 300.9 0.1 5.2e-90 300.3 0.1 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 EPS26090.1 - 2.5e-77 260.0 0.0 3.5e-77 259.5 0.0 1.2 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.19 EPS26090.1 - 0.0015 18.2 0.3 0.0086 15.7 0.0 2.3 3 0 0 3 3 3 1 MIF4G domain WD40 PF00400.32 EPS26091.1 - 1.1e-30 105.2 27.3 1.9e-05 25.4 0.0 11.9 13 0 0 13 13 13 8 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EPS26091.1 - 2.6e-06 26.7 0.1 0.2 10.6 0.0 4.6 4 1 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 EPS26091.1 - 4.2e-05 23.5 0.0 16 5.6 0.0 5.5 7 0 0 7 7 7 2 Ciliary BBSome complex subunit 2, middle region Urm1 PF09138.11 EPS26092.1 - 1.5e-36 124.7 0.0 1.7e-36 124.5 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 EPS26092.1 - 0.00035 21.1 0.0 0.00043 20.9 0.0 1.2 1 0 0 1 1 1 1 ThiS family 6PF2K PF01591.18 EPS26093.1 - 6.3e-65 218.6 0.0 8.6e-65 218.2 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EPS26093.1 - 1.5e-19 70.5 0.2 7.2e-19 68.2 0.2 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EPS26093.1 - 0.031 14.4 0.0 0.082 13.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 EPS26093.1 - 0.11 12.3 0.0 1.2 9.0 0.0 2.3 1 1 0 1 1 1 0 Adenylylsulphate kinase Porin_3 PF01459.22 EPS26094.1 - 1.9e-83 280.1 0.1 2.2e-83 279.9 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin Zds_C PF08632.10 EPS26094.1 - 0.0042 16.8 0.0 0.0092 15.7 0.0 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Pkinase PF00069.25 EPS26095.1 - 2e-66 224.1 0.0 2.3e-66 223.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS26095.1 - 8.1e-25 87.6 0.0 9.8e-25 87.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EPS26095.1 - 7.8e-06 25.4 0.0 3.6e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EPS26095.1 - 0.0019 18.2 0.2 0.02 14.8 0.0 2.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 EPS26095.1 - 0.18 11.1 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC_tran PF00005.27 EPS26098.1 - 1.2e-15 58.2 0.2 1.1e-14 55.1 0.2 2.1 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EPS26098.1 - 7.3e-11 42.4 1.8 9.7e-05 22.3 0.2 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EPS26098.1 - 0.00055 19.4 0.0 0.25 10.7 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EPS26098.1 - 0.00068 19.3 0.2 0.0013 18.4 0.2 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3584 PF12128.8 EPS26098.1 - 0.0026 15.4 0.2 0.0035 14.9 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) PduV-EutP PF10662.9 EPS26098.1 - 0.0046 16.7 0.0 0.007 16.1 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 EPS26098.1 - 0.0058 17.1 0.0 0.0093 16.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EPS26098.1 - 0.0064 16.9 0.5 0.015 15.7 0.5 1.6 1 1 0 1 1 1 1 AAA ATPase domain FANCF PF11107.8 EPS26098.1 - 0.0077 15.5 0.3 0.011 15.0 0.3 1.1 1 0 0 1 1 1 1 Fanconi anemia group F protein (FANCF) RsgA_GTPase PF03193.16 EPS26098.1 - 0.0088 16.0 0.1 0.014 15.3 0.1 1.2 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 EPS26098.1 - 0.0088 15.6 0.1 0.017 14.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EPS26098.1 - 0.011 15.4 0.0 0.016 15.0 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain Roc PF08477.13 EPS26098.1 - 0.032 14.5 0.1 0.1 12.8 0.0 1.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 EPS26098.1 - 0.04 14.1 1.1 0.089 13.0 1.1 1.6 1 0 0 1 1 1 0 AAA domain DUF3864 PF12980.7 EPS26098.1 - 0.062 13.6 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3864) Arf PF00025.21 EPS26098.1 - 0.09 12.2 0.2 0.19 11.2 0.2 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family DLIC PF05783.11 EPS26098.1 - 0.11 11.4 0.1 0.18 10.6 0.1 1.2 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA PF00004.29 EPS26098.1 - 0.11 12.9 0.1 0.72 10.3 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EPS26098.1 - 0.13 12.5 0.5 0.31 11.3 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 EPS26098.1 - 0.15 10.7 0.3 0.2 10.2 0.3 1.1 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EPS26098.1 - 0.18 11.5 0.0 0.31 10.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain IPPT PF01715.17 EPS26099.1 - 7.9e-62 209.0 0.1 1.1e-61 208.5 0.1 1.1 1 0 0 1 1 1 1 IPP transferase AAA_33 PF13671.6 EPS26099.1 - 0.001 19.3 0.0 0.23 11.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain zf-C2H2_jaz PF12171.8 EPS26099.1 - 0.0013 18.9 0.1 0.0024 18.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding IPT PF01745.16 EPS26099.1 - 0.0054 16.1 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Isopentenyl transferase zf-met PF12874.7 EPS26099.1 - 0.0058 17.0 0.2 0.011 16.1 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type AAA_25 PF13481.6 EPS26099.1 - 0.014 15.0 0.2 0.12 11.9 0.0 2.4 3 0 0 3 3 3 0 AAA domain DUF3449 PF11931.8 EPS26099.1 - 0.015 15.1 0.1 0.033 14.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) AAA_18 PF13238.6 EPS26099.1 - 0.023 15.3 0.1 0.87 10.1 0.0 3.0 2 1 0 3 3 3 0 AAA domain Cytidylate_kin PF02224.18 EPS26099.1 - 0.08 12.7 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase AAA_16 PF13191.6 EPS26099.1 - 0.099 13.0 0.4 1.2 9.5 0.0 2.6 3 1 0 3 3 3 0 AAA ATPase domain zf-C2H2_2 PF12756.7 EPS26099.1 - 0.13 12.6 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Ploopntkinase3 PF18751.1 EPS26099.1 - 0.17 11.8 0.5 2.9 7.8 0.0 2.6 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 RAI1 PF08652.11 EPS26100.1 - 1.4e-29 102.1 0.0 3.5e-29 100.8 0.0 1.7 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease DUF410 PF04190.13 EPS26101.1 - 6.7e-84 281.7 0.0 8.1e-84 281.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Rep_fac_C PF08542.11 EPS26103.1 - 8.2e-24 83.8 0.1 6.1e-23 81.1 0.0 2.2 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 EPS26103.1 - 1.1e-11 44.8 0.0 1.8e-08 34.4 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 EPS26103.1 - 1.5e-11 44.8 0.0 2.8e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EPS26103.1 - 5.8e-08 32.8 0.0 2.8e-07 30.6 0.0 2.1 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.6 EPS26103.1 - 5.9e-07 30.0 0.0 2.9e-05 24.5 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_3 PF07726.11 EPS26103.1 - 6.4e-06 26.1 0.0 1.2e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EPS26103.1 - 1.7e-05 25.1 0.0 0.011 16.0 0.0 2.5 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EPS26103.1 - 1.8e-05 24.6 0.0 2.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.12 EPS26103.1 - 3.7e-05 23.5 0.0 8.7e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DNA_pol3_delta PF06144.13 EPS26103.1 - 0.00015 21.6 0.0 0.00023 21.0 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 EPS26103.1 - 0.00062 19.2 0.0 0.0055 16.1 0.0 2.1 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Rad17 PF03215.15 EPS26103.1 - 0.00099 19.1 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain MeaB PF03308.16 EPS26103.1 - 0.001 18.1 0.0 0.0019 17.3 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB KTI12 PF08433.10 EPS26103.1 - 0.005 16.3 0.0 0.0079 15.7 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 NTPase_1 PF03266.15 EPS26103.1 - 0.0091 15.9 0.0 0.025 14.5 0.0 1.8 1 0 0 1 1 1 1 NTPase AAA_19 PF13245.6 EPS26103.1 - 0.012 15.9 0.1 0.045 14.1 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_assoc_2 PF16193.5 EPS26103.1 - 0.027 14.8 0.0 0.085 13.2 0.0 1.9 2 0 0 2 2 1 0 AAA C-terminal domain TniB PF05621.11 EPS26103.1 - 0.03 13.7 0.0 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein AAA_30 PF13604.6 EPS26103.1 - 0.037 13.7 0.0 0.12 12.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EPS26103.1 - 0.052 14.1 0.0 0.11 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EPS26103.1 - 0.053 13.2 0.0 0.31 10.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EPS26103.1 - 0.063 12.8 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_5 PF07728.14 EPS26103.1 - 0.072 13.1 0.0 0.2 11.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EPS26103.1 - 0.08 13.3 0.0 0.23 11.9 0.0 1.8 2 0 0 2 2 1 0 RNA helicase AAA_11 PF13086.6 EPS26103.1 - 0.087 12.6 0.0 0.13 12.0 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EPS26103.1 - 0.091 12.9 0.1 0.18 12.0 0.1 1.5 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EPS26103.1 - 0.095 12.6 0.0 0.35 10.8 0.0 1.8 2 0 0 2 2 2 0 NACHT domain Thymidylate_kin PF02223.17 EPS26103.1 - 0.11 12.2 0.1 0.44 10.2 0.0 1.9 2 0 0 2 2 2 0 Thymidylate kinase FtsK_SpoIIIE PF01580.18 EPS26103.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_28 PF13521.6 EPS26103.1 - 0.14 12.3 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zn_clus PF00172.18 EPS26104.1 - 3.1e-09 36.8 9.9 3.1e-09 36.8 9.9 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPS26104.1 - 3e-06 26.5 1.6 3.4e-06 26.3 0.3 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF4802 PF16060.5 EPS26104.1 - 0.16 12.2 2.8 0.34 11.1 2.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4802) Glyco_hydro_32N PF00251.20 EPS26105.1 - 8.7e-42 143.7 0.0 3.8e-41 141.6 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 EPS26105.1 - 3.6e-27 95.3 0.3 5.2e-27 94.8 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR PF02012.20 EPS26105.1 - 0.012 15.5 1.2 0.65 10.2 0.0 3.3 2 0 0 2 2 2 0 BNR/Asp-box repeat DUF4975 PF16346.5 EPS26105.1 - 0.18 11.9 0.0 0.43 10.6 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4975) Sugar_tr PF00083.24 EPS26106.1 - 3.8e-77 260.1 14.7 4.4e-77 259.8 14.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS26106.1 - 2.8e-24 85.7 37.8 1e-23 83.9 20.5 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily AA_permease_2 PF13520.6 EPS26107.1 - 4.5e-67 226.7 34.8 5.9e-67 226.3 34.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPS26107.1 - 8.6e-27 93.9 23.1 8.6e-27 93.9 23.1 2.3 2 1 0 2 2 2 1 Amino acid permease PrgI PF12666.7 EPS26107.1 - 0.11 13.2 0.2 0.11 13.2 0.2 3.8 5 1 0 5 5 5 0 PrgI family protein NAD_binding_1 PF00175.21 EPS26108.1 - 1e-05 26.1 0.0 0.019 15.6 0.0 2.4 1 1 0 2 2 2 2 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EPS26108.1 - 8.5e-05 22.8 0.0 0.00039 20.7 0.0 2.2 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EPS26108.1 - 0.014 15.5 0.0 0.024 14.7 0.0 1.5 1 1 0 1 1 1 0 Ferric reductase NAD binding domain Aminotran_5 PF00266.19 EPS26109.1 - 1.7e-28 99.6 0.0 1.1e-17 64.1 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V DUF4328 PF14219.6 EPS26109.1 - 0.05 13.1 0.0 0.18 11.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) Aconitase PF00330.20 EPS26110.1 - 7.2e-110 368.1 0.2 7.3e-109 364.8 0.2 2.0 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EPS26110.1 - 3.5e-24 85.6 0.0 6.9e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain HetR_C PF18460.1 EPS26111.1 - 0.2 11.6 0.4 1.4 8.9 0.1 2.1 2 0 0 2 2 2 0 Heterocyst differentiation regulator C-terminal Hood domain Chorismate_bind PF00425.18 EPS26112.1 - 3e-67 226.9 0.0 3.1e-65 220.3 0.0 2.2 1 1 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 EPS26112.1 - 1.1e-25 90.6 0.0 2e-25 89.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 EPS26112.1 - 3.7e-10 40.2 0.0 1.9e-09 37.9 0.0 2.3 2 1 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 EPS26112.1 - 0.0021 17.9 0.7 0.013 15.3 0.7 2.2 1 1 0 1 1 1 1 Peptidase C26 CdiI_N PF18228.1 EPS26112.1 - 0.12 12.3 0.1 0.6 10.0 0.0 2.1 2 0 0 2 2 2 0 CdiI N-terminal domain DUF3684 PF12449.8 EPS26113.1 - 0 1427.9 0.0 0 1427.9 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.6 EPS26113.1 - 0.00028 20.7 0.0 0.00069 19.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WLM PF08325.10 EPS26113.1 - 0.91 9.6 5.5 0.44 10.6 0.4 2.3 2 0 0 2 2 2 0 WLM domain Bud13 PF09736.9 EPS26113.1 - 1.7 9.0 8.3 3.8 7.9 8.3 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Hydin_ADK PF17213.3 EPS26113.1 - 2.5 8.3 9.1 6.9 6.9 9.1 1.7 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DUF572 PF04502.13 EPS26113.1 - 5.4 6.5 12.2 9.3 5.8 12.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) TRAPPC9-Trs120 PF08626.11 EPS26114.1 - 0 1502.6 0.0 0 1502.4 0.0 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_12 PF13424.6 EPS26114.1 - 0.061 13.6 0.1 0.13 12.5 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Ig_GlcNase PF18368.1 EPS26114.1 - 0.15 12.3 0.0 30 4.8 0.0 3.1 3 0 0 3 3 3 0 Exo-beta-D-glucosaminidase Ig-fold domain adh_short PF00106.25 EPS26115.1 - 2.8e-34 118.3 0.0 3.7e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS26115.1 - 2.4e-22 79.6 0.0 3.1e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPS26115.1 - 4.5e-13 49.5 0.0 6.8e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPS26115.1 - 7.1e-07 28.9 0.1 1.4e-06 28.0 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EPS26115.1 - 4.4e-05 22.8 0.0 5.5e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EPS26115.1 - 7.8e-05 21.9 0.0 0.00011 21.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 EPS26115.1 - 0.013 14.5 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EPS26115.1 - 0.032 14.1 0.1 0.044 13.7 0.1 1.4 1 1 0 1 1 1 0 NAD(P)H-binding NmrA PF05368.13 EPS26115.1 - 0.059 12.9 0.0 0.096 12.2 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family DapB_N PF01113.20 EPS26115.1 - 0.079 13.1 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.12 EPS26115.1 - 0.097 11.8 0.0 12 4.9 0.0 2.3 2 0 0 2 2 2 0 Male sterility protein Synaptonemal_3 PF15191.6 EPS26115.1 - 0.2 11.5 0.0 0.35 10.7 0.0 1.3 1 0 0 1 1 1 0 Synaptonemal complex central element protein 3 Sec1 PF00995.23 EPS26116.1 - 5e-131 438.8 0.1 5.8e-131 438.5 0.1 1.0 1 0 0 1 1 1 1 Sec1 family MBOAT PF03062.19 EPS26117.1 - 5.3e-55 187.2 8.1 1.4e-54 185.8 8.1 1.7 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF3961 PF13106.6 EPS26117.1 - 0.014 15.0 1.2 0.045 13.4 1.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3961) Synaptobrevin PF00957.21 EPS26118.1 - 0.0052 16.5 1.8 0.011 15.5 1.8 1.5 1 0 0 1 1 1 1 Synaptobrevin CPBP PF02517.16 EPS26120.1 - 6.4e-17 61.7 15.9 1.6e-16 60.4 5.6 2.9 3 1 0 3 3 3 2 CPBP intramembrane metalloprotease DUF4244 PF14029.6 EPS26120.1 - 0.53 9.8 2.8 0.55 9.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4244) Methyltransf_25 PF13649.6 EPS26121.1 - 6e-05 23.7 0.0 0.00018 22.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Epimerase PF01370.21 EPS26122.1 - 1.5e-08 34.4 0.2 5.4e-05 22.8 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EPS26122.1 - 2.5e-08 34.1 0.4 3.8e-07 30.2 0.4 2.1 1 1 1 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EPS26122.1 - 8.9e-06 25.4 0.2 1.3e-05 24.8 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 EPS26122.1 - 1.7e-05 24.0 0.1 3e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EPS26122.1 - 0.046 12.9 0.1 0.93 8.6 0.0 2.3 2 1 0 2 2 2 0 Male sterility protein tRNA-synt_1 PF00133.22 EPS26123.1 - 9.5e-55 186.0 0.0 2.7e-20 72.2 0.0 6.1 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 EPS26123.1 - 1.6e-40 138.6 0.0 2.6e-40 137.9 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 EPS26123.1 - 1.7e-27 96.2 0.0 4.2e-21 75.1 0.0 4.2 3 1 1 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EPS26123.1 - 1.5e-08 34.8 0.0 3.2e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.19 EPS26123.1 - 0.003 16.6 0.0 0.0049 15.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) tRNA-synt_1e PF01406.19 EPS26123.1 - 0.18 11.1 0.0 1.5 8.1 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain ZirS_C PF16583.5 EPS26124.1 - 0.11 12.1 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Zinc-regulated secreted antivirulence protein C-terminal domain Suc_Fer-like PF06999.12 EPS26125.1 - 1.6e-58 197.8 0.0 1.9e-58 197.6 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like DUF3669 PF12417.8 EPS26127.1 - 2.9e-20 72.2 0.2 6.4e-20 71.1 0.2 1.6 1 0 0 1 1 1 1 Zinc finger protein p450 PF00067.22 EPS26128.1 - 3.5e-31 108.5 0.0 4.6e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_25 PF13649.6 EPS26129.1 - 3.2e-11 43.8 0.0 5.4e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS26129.1 - 5.2e-11 43.0 0.0 1.1e-10 42.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPS26129.1 - 5.4e-09 35.7 0.0 9.1e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EPS26129.1 - 7.9e-07 29.0 0.0 1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPS26129.1 - 0.00015 22.4 0.0 0.00024 21.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPS26129.1 - 0.00017 21.4 0.0 0.00026 20.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EPS26129.1 - 0.023 14.3 0.0 0.66 9.5 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Trp_DMAT PF11991.8 EPS26130.1 - 3.1e-94 316.4 0.0 3.6e-94 316.2 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase MFS_1 PF07690.16 EPS26131.1 - 2e-42 145.4 45.9 4.3e-42 144.3 45.9 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EPS26131.1 - 7.7e-12 44.4 20.4 1.9e-11 43.1 20.4 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FAD_binding_3 PF01494.19 EPS26132.1 - 8e-16 58.2 7.4 3.9e-09 36.2 0.1 2.9 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 EPS26132.1 - 2.3e-06 27.5 5.3 0.012 15.2 1.2 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EPS26132.1 - 2.4e-06 26.9 0.2 4.1e-06 26.2 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EPS26132.1 - 8.1e-05 22.0 0.7 0.21 10.8 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EPS26132.1 - 0.00044 19.4 0.2 0.00083 18.5 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 EPS26132.1 - 0.00089 18.1 0.5 0.022 13.5 0.3 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 EPS26132.1 - 0.0047 16.3 1.2 0.0073 15.7 1.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EPS26132.1 - 0.074 12.3 0.2 0.13 11.6 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 EPS26132.1 - 0.12 12.6 0.2 0.52 10.6 0.2 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Methyltransf_2 PF00891.18 EPS26133.1 - 4.9e-16 58.7 0.0 1.1e-15 57.6 0.0 1.5 2 0 0 2 2 2 1 O-methyltransferase domain Dimerisation2 PF16864.5 EPS26133.1 - 0.00076 19.4 0.0 0.0069 16.3 0.0 2.3 2 0 0 2 2 2 1 Dimerisation domain p450 PF00067.22 EPS26134.1 - 1.4e-43 149.3 0.0 1.9e-43 148.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.28 EPS26135.1 - 5.6e-138 460.1 0.0 5.4e-70 236.1 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 EPS26135.1 - 1.9e-75 254.3 0.0 1e-40 139.8 0.1 4.1 2 2 0 2 2 2 2 Condensation domain PP-binding PF00550.25 EPS26135.1 - 1.6e-23 82.8 0.1 7.5e-13 48.6 0.1 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EPS26135.1 - 6.4e-06 27.1 0.0 0.28 12.2 0.0 3.2 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain PPDK_N PF01326.19 EPS26136.1 - 9.1e-108 360.4 0.0 1.3e-107 359.9 0.0 1.1 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers_C PF02896.18 EPS26136.1 - 3.8e-61 206.8 0.0 5.8e-61 206.2 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilizers PF00391.23 EPS26136.1 - 5.4e-24 83.7 0.3 1.3e-23 82.5 0.3 1.7 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain Methyltransf_25 PF13649.6 EPS26137.1 - 0.049 14.3 0.0 0.52 11.1 0.0 2.6 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_23 PF13489.6 EPS26137.1 - 0.049 13.5 0.0 0.09 12.6 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 EPS26137.1 - 0.093 13.5 0.0 0.31 11.8 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain p450 PF00067.22 EPS26138.1 - 1.7e-63 215.0 0.0 2.2e-63 214.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1731 PF08338.11 EPS26138.1 - 0.011 15.5 0.0 0.078 12.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1731) Terpene_synth_C PF03936.16 EPS26139.1 - 0.0078 15.6 0.4 0.092 12.1 0.0 2.4 2 1 1 3 3 3 1 Terpene synthase family, metal binding domain p450 PF00067.22 EPS26140.1 - 3.3e-43 148.1 0.0 7.7e-43 146.9 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 POTRA_TamA_1 PF17243.2 EPS26140.1 - 0.04 14.0 0.6 0.09 12.9 0.6 1.6 1 0 0 1 1 1 0 POTRA domain TamA domain 1 AMP-binding PF00501.28 EPS26141.1 - 6.9e-77 258.8 0.0 1.2e-76 258.0 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EPS26141.1 - 1.2e-29 103.3 0.0 2.4e-27 95.8 0.0 3.3 3 1 0 3 3 3 2 Condensation domain PP-binding PF00550.25 EPS26141.1 - 2.1e-08 34.4 0.0 7.3e-08 32.7 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EPS26141.1 - 3.1e-05 24.8 0.0 7.9e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ldh_1_N PF00056.23 EPS26142.1 - 1.6e-21 76.9 0.1 2.2e-21 76.4 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 EPS26142.1 - 3.3e-11 43.4 0.0 2.4e-10 40.6 0.0 2.2 2 1 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.16 EPS26142.1 - 0.0022 17.6 0.1 0.0057 16.2 0.0 1.7 1 1 1 2 2 2 1 Family 4 glycosyl hydrolase F420_oxidored PF03807.17 EPS26142.1 - 0.0035 17.9 0.2 0.02 15.5 0.1 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.18 EPS26142.1 - 0.015 15.5 0.6 0.029 14.6 0.6 1.5 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.19 EPS26144.1 - 9.7e-51 171.6 0.0 1.8e-50 170.8 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EPS26144.1 - 1.1e-15 57.5 0.0 1.5e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AlaDh_PNT_C PF01262.21 EPS26144.1 - 0.016 14.6 0.1 0.99 8.6 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FH2 PF02181.23 EPS26146.1 - 5.9e-91 305.4 6.0 5.9e-91 305.4 6.0 1.8 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 EPS26146.1 - 3.8e-69 232.0 0.9 1.2e-68 230.3 0.0 2.3 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 EPS26146.1 - 6e-52 176.1 0.3 1.8e-50 171.3 0.0 2.7 1 1 1 2 2 2 1 Diaphanous FH3 Domain CobU PF02283.16 EPS26146.1 - 0.13 11.9 0.2 0.3 10.6 0.2 1.6 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase TrmE_N PF10396.9 EPS26147.1 - 6.5e-37 126.4 0.0 1.4e-36 125.3 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MnmE_helical PF12631.7 EPS26147.1 - 7.4e-30 104.7 0.0 2.7e-29 102.8 0.0 1.9 1 1 0 1 1 1 1 MnmE helical domain MMR_HSR1 PF01926.23 EPS26147.1 - 3.6e-19 68.9 0.0 6.1e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EPS26147.1 - 4.9e-05 22.9 0.1 0.00024 20.7 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 EPS26147.1 - 5.9e-05 22.7 0.0 0.0054 16.3 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EPS26147.1 - 0.00025 21.2 0.0 0.00039 20.5 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Glyco_hydro_3_C PF01915.22 EPS26147.1 - 0.0028 17.6 0.1 0.0043 17.0 0.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain RsgA_GTPase PF03193.16 EPS26147.1 - 0.0099 15.8 0.0 0.068 13.1 0.0 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_24 PF13479.6 EPS26147.1 - 0.012 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 EPS26147.1 - 0.16 12.2 0.1 0.56 10.4 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Med6 PF04934.14 EPS26148.1 - 1e-38 132.2 0.0 1.3e-38 131.8 0.0 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component Lysine_decarbox PF03641.14 EPS26149.1 - 3e-28 98.5 0.1 9.9e-28 96.9 0.1 1.8 1 1 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 EPS26149.1 - 0.0061 16.2 1.4 0.021 14.4 0.1 2.2 1 1 1 2 2 2 1 SLOG cluster4 family DAGK_cat PF00781.24 EPS26149.1 - 0.047 13.3 1.0 2.6 7.7 0.1 2.7 3 0 0 3 3 3 0 Diacylglycerol kinase catalytic domain Proteasome PF00227.26 EPS26150.1 - 1.2e-49 168.4 0.1 1.5e-49 168.1 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EPS26150.1 - 1.2e-12 47.2 0.4 2e-12 46.5 0.4 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Vps55 PF04133.14 EPS26151.1 - 4.8e-46 155.5 6.4 5.5e-46 155.3 6.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF4349 PF14257.6 EPS26151.1 - 0.42 10.0 0.0 0.42 10.0 0.0 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4349) DUF4231 PF14015.6 EPS26151.1 - 0.57 10.7 2.2 5.1 7.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Sld7_C PF18596.1 EPS26152.1 - 5.1e-14 52.2 0.0 1.2e-13 50.9 0.0 1.6 1 1 0 1 1 1 1 Sld7 C-terminal domain UPF0220 PF05255.11 EPS26153.1 - 5.8e-72 240.6 3.7 6.5e-72 240.5 3.7 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Fes1 PF08609.10 EPS26154.1 - 2.4e-32 111.7 2.9 2.4e-32 111.7 2.9 2.1 2 1 1 3 3 3 1 Nucleotide exchange factor Fes1 HEAT_EZ PF13513.6 EPS26154.1 - 4.3e-07 30.3 0.8 4.6e-05 23.8 0.2 2.0 1 1 1 2 2 2 2 HEAT-like repeat Arm PF00514.23 EPS26154.1 - 1.5e-05 24.8 0.1 0.00075 19.4 0.0 2.4 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EPS26154.1 - 4.1e-05 23.5 0.2 0.029 14.6 0.0 2.7 2 0 0 2 2 2 2 HEAT repeat HEAT_2 PF13646.6 EPS26154.1 - 7.2e-05 23.1 0.4 0.00039 20.7 0.2 2.2 2 1 0 2 2 2 1 HEAT repeats Atx10homo_assoc PF09759.9 EPS26154.1 - 0.088 12.8 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain Actin PF00022.19 EPS26156.1 - 4.7e-150 499.7 0.0 1.8e-149 497.8 0.0 1.7 1 1 0 1 1 1 1 Actin GARS_A PF01071.19 EPS26157.1 - 2.6e-81 272.0 0.0 3.9e-81 271.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 EPS26157.1 - 1.6e-34 118.6 0.2 6.7e-34 116.5 0.0 2.3 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 EPS26157.1 - 2e-34 118.9 0.0 5.1e-34 117.7 0.0 1.7 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 EPS26157.1 - 3.3e-28 97.8 0.2 1e-27 96.2 0.2 2.0 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 EPS26157.1 - 7.1e-14 52.2 2.5 7.1e-14 52.2 2.5 2.2 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp PF02222.22 EPS26157.1 - 0.0018 17.9 0.0 0.0031 17.1 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 EPS26157.1 - 0.0065 16.0 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.6 EPS26157.1 - 0.0087 15.7 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EPS26157.1 - 0.021 14.9 0.0 0.082 13.0 0.0 2.1 2 1 0 2 2 2 0 ATP-grasp domain ATP-grasp_2 PF08442.10 EPS26157.1 - 0.024 14.2 0.0 0.057 13.0 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain RimK PF08443.11 EPS26157.1 - 0.042 13.5 0.1 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Pet127 PF08634.10 EPS26158.1 - 1.1e-119 398.9 1.0 1.6e-119 398.4 1.0 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 MFS_1 PF07690.16 EPS26159.1 - 1.6e-40 139.2 49.1 4.7e-40 137.6 49.1 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS26159.1 - 2.3e-12 46.5 23.7 2.3e-11 43.2 8.9 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter DUF4188 PF13826.6 EPS26160.1 - 7.7e-32 110.1 0.0 1.1e-31 109.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.6 EPS26160.1 - 0.058 12.8 0.0 0.082 12.3 0.0 1.2 1 0 0 1 1 1 0 Haem-containing dehydratase LRR_6 PF13516.6 EPS26161.1 - 0.089 12.9 0.1 78 3.7 0.0 5.1 6 0 0 6 6 6 0 Leucine Rich repeat IGPD PF00475.18 EPS26163.1 - 3.2e-55 186.4 0.7 4.9e-55 185.8 0.7 1.3 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Gly_transf_sug PF04488.15 EPS26165.1 - 9e-21 74.3 0.0 1.6e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 EPS26165.1 - 0.027 13.9 0.1 0.046 13.1 0.1 1.3 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Vps23_core PF09454.10 EPS26167.1 - 0.082 12.9 0.1 0.11 12.5 0.1 1.2 1 0 0 1 1 1 0 Vps23 core domain DER1 PF04511.15 EPS26168.1 - 1.9e-50 171.4 3.9 2.2e-50 171.2 3.9 1.0 1 0 0 1 1 1 1 Der1-like family Histone PF00125.24 EPS26169.1 - 1.6e-42 145.0 0.1 1.8e-42 144.8 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EPS26169.1 - 2.6e-05 24.3 0.0 4.1e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EPS26169.1 - 0.0011 19.2 0.1 0.0019 18.5 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 EPS26169.1 - 0.036 14.3 0.8 0.072 13.4 0.8 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EPS26169.1 - 0.066 13.3 0.1 0.092 12.8 0.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TEBP_beta PF07404.11 EPS26169.1 - 3.6 6.9 5.6 2.8 7.2 4.3 1.5 2 0 0 2 2 2 0 Telomere-binding protein beta subunit (TEBP beta) Cohesin_load PF10345.9 EPS26170.1 - 4.2e-172 573.7 1.8 5.7e-172 573.3 1.8 1.2 1 0 0 1 1 1 1 Cohesin loading factor HemY_N PF07219.13 EPS26170.1 - 0.11 12.6 1.0 1.7 8.9 0.4 2.8 2 0 0 2 2 2 0 HemY protein N-terminus TPR_16 PF13432.6 EPS26170.1 - 0.25 12.0 7.1 0.41 11.3 1.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat HTH_WhiA PF02650.14 EPS26170.1 - 0.27 11.6 1.6 0.76 10.2 0.2 2.3 2 0 0 2 2 2 0 WhiA C-terminal HTH domain Abhydrolase_1 PF00561.20 EPS26171.1 - 1.1e-10 41.6 0.1 3e-10 40.2 0.1 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EPS26171.1 - 7.3e-08 32.0 0.0 2.8e-07 30.1 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DUF5301 PF17225.3 EPS26172.1 - 0.15 12.5 2.2 0.39 11.2 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5300) Complex1_LYR PF05347.15 EPS26173.1 - 2.2e-06 27.6 0.1 4.1e-06 26.8 0.1 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EPS26173.1 - 2.2e-06 28.3 0.1 3.2e-06 27.8 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like IKKbetaNEMObind PF12179.8 EPS26173.1 - 0.023 14.7 0.0 0.78 9.8 0.0 2.3 2 0 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain WbqC PF08889.11 EPS26173.1 - 0.072 13.0 0.1 0.34 10.8 0.0 1.9 1 1 1 2 2 2 0 WbqC-like protein family ATP-grasp_2 PF08442.10 EPS26175.1 - 8.7e-56 188.7 0.0 1.2e-55 188.2 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 EPS26175.1 - 3e-17 62.9 0.4 1.9e-16 60.2 0.2 2.1 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.6 EPS26175.1 - 1.3e-09 37.9 0.0 6.5e-09 35.6 0.0 2.0 2 1 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 EPS26175.1 - 0.00027 20.7 0.0 0.00066 19.5 0.0 1.7 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.17 EPS26175.1 - 0.00039 20.0 0.1 0.00081 18.9 0.1 1.6 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.22 EPS26175.1 - 0.0041 16.7 0.0 0.0083 15.7 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain THF_DHG_CYH PF00763.23 EPS26175.1 - 0.16 12.2 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain F-box-like PF12937.7 EPS26176.1 - 0.0061 16.4 0.2 0.012 15.5 0.2 1.5 1 0 0 1 1 1 1 F-box-like Hydrophobin PF01185.18 EPS26177.1 - 0.21 12.3 8.5 2 9.1 0.7 2.2 1 1 1 2 2 2 0 Fungal hydrophobin Hydrophobin PF01185.18 EPS26178.1 - 0.16 12.6 6.5 2.4 8.9 1.1 2.3 1 1 1 2 2 2 0 Fungal hydrophobin TPP_enzyme_C PF02775.21 EPS26178.1 - 0.69 9.7 4.1 11 5.8 0.2 2.0 1 1 1 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain RNA_pol_L_2 PF13656.6 EPS26179.1 - 2.4e-31 107.3 0.0 3.2e-31 106.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EPS26179.1 - 2.8e-14 52.3 0.0 3.9e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain PRMT5_TIM PF17285.2 EPS26180.1 - 0.029 13.6 0.8 0.035 13.3 0.8 1.1 1 0 0 1 1 1 0 PRMT5 TIM barrel domain DUF697 PF05128.12 EPS26180.1 - 0.052 13.2 2.6 0.073 12.8 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF697) YpjP PF14005.6 EPS26180.1 - 0.065 13.3 1.1 0.13 12.3 1.0 1.5 1 1 0 1 1 1 0 YpjP-like protein Helo_like_N PF17111.5 EPS26182.1 - 4.2e-72 241.9 6.4 8.4e-72 240.9 6.4 1.5 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 EPS26182.1 - 0.0039 17.4 1.1 0.01 16.0 0.1 2.1 2 1 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Spc7 PF08317.11 EPS26182.1 - 0.012 14.5 4.4 0.053 12.4 0.2 2.4 2 0 0 2 2 2 0 Spc7 kinetochore protein RasGAP_C PF03836.15 EPS26182.1 - 0.012 15.7 2.2 0.15 12.2 0.1 2.5 2 0 0 2 2 2 0 RasGAP C-terminus Bacillus_HBL PF05791.11 EPS26182.1 - 0.015 15.1 0.2 0.21 11.4 0.0 2.3 1 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Fib_alpha PF08702.10 EPS26182.1 - 0.033 14.4 4.8 0.18 12.0 0.1 2.4 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DASH_Duo1 PF08651.10 EPS26182.1 - 0.073 12.9 0.2 0.77 9.6 0.0 2.5 2 0 0 2 2 2 0 DASH complex subunit Duo1 Rx_N PF18052.1 EPS26182.1 - 0.079 13.2 1.8 0.15 12.3 0.2 2.4 2 1 1 3 3 3 0 Rx N-terminal domain SbcD_C PF12320.8 EPS26182.1 - 0.085 13.2 0.2 5.4 7.4 0.0 2.8 1 1 1 2 2 2 0 Type 5 capsule protein repressor C-terminal domain Baculo_PEP_C PF04513.12 EPS26182.1 - 0.12 12.4 2.0 2.9 7.9 0.1 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Muted PF14942.6 EPS26182.1 - 0.23 11.8 3.0 13 6.1 0.0 2.3 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein ATG16 PF08614.11 EPS26182.1 - 0.3 11.3 4.5 1.5 9.0 0.6 2.7 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Syntaxin-6_N PF09177.11 EPS26182.1 - 0.31 11.6 4.3 3.7 8.2 0.5 3.1 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Med9 PF07544.13 EPS26182.1 - 0.39 10.8 6.6 8.1 6.6 0.5 3.3 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 TPR_MLP1_2 PF07926.12 EPS26182.1 - 0.66 10.0 5.4 13 5.8 0.4 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein SKA1 PF07160.12 EPS26182.1 - 1.2 8.9 4.5 2.2 8.1 0.3 2.3 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 HAD_2 PF13419.6 EPS26184.1 - 1.2e-10 41.7 0.0 5.8e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EPS26184.1 - 0.013 15.8 0.0 1.3 9.3 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase TPR_12 PF13424.6 EPS26185.1 - 9.5e-05 22.6 0.0 0.08 13.2 0.0 2.5 2 1 0 2 2 2 2 Tetratricopeptide repeat Death PF00531.22 EPS26187.1 - 0.13 12.4 0.0 0.38 10.9 0.0 1.7 2 0 0 2 2 2 0 Death domain GGACT PF06094.12 EPS26188.1 - 0.086 13.5 0.0 0.11 13.1 0.0 1.2 1 0 0 1 1 1 0 Gamma-glutamyl cyclotransferase, AIG2-like Amidoligase_2 PF12224.8 EPS26189.1 - 0.00033 20.4 0.0 0.00043 20.0 0.0 1.1 1 0 0 1 1 1 1 Putative amidoligase enzyme AAA PF00004.29 EPS26191.1 - 5.2e-09 36.6 0.0 3.2e-08 34.0 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 EPS26191.1 - 0.035 14.5 0.0 0.099 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain RVT_1 PF00078.27 EPS26195.1 - 2.4e-34 118.8 0.0 3.4e-34 118.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.6 EPS26195.1 - 0.00057 19.7 0.0 0.0014 18.4 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase BTB PF00651.31 EPS26198.1 - 1e-12 48.3 0.2 2.3e-12 47.1 0.1 1.6 2 0 0 2 2 2 1 BTB/POZ domain Tetraspanin PF00335.20 EPS26200.1 - 5.3e-07 29.6 2.8 1.2e-06 28.4 2.8 1.6 1 1 0 1 1 1 1 Tetraspanin family TrbC PF04956.13 EPS26200.1 - 0.089 13.0 0.6 0.089 13.0 0.6 3.1 3 0 0 3 3 3 0 TrbC/VIRB2 family MCRA PF06100.11 EPS26203.1 - 5.9e-179 596.0 0.0 7.1e-179 595.7 0.0 1.0 1 0 0 1 1 1 1 MCRA family Endosulfine PF04667.17 EPS26204.1 - 1.9e-13 50.3 0.3 2.7e-12 46.6 0.0 2.0 1 1 1 2 2 2 1 cAMP-regulated phosphoprotein/endosulfine conserved region DUF1640 PF07798.11 EPS26205.1 - 1.4e-34 119.6 3.0 2e-34 119.1 3.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) LURAP PF14854.6 EPS26205.1 - 0.1 12.5 2.1 0.47 10.4 0.4 2.7 1 1 1 2 2 2 0 Leucine rich adaptor protein Seryl_tRNA_N PF02403.22 EPS26205.1 - 0.85 9.9 6.0 0.46 10.7 2.2 2.3 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ATP-synt_ab PF00006.25 EPS26208.1 - 1.7e-72 243.5 0.0 2.3e-72 243.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 EPS26208.1 - 2.6e-45 153.8 0.1 4.4e-45 153.1 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 EPS26208.1 - 3.3e-12 46.7 1.2 7.9e-12 45.5 0.9 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain Radical_SAM_C PF16199.5 EPS26208.1 - 0.045 13.8 0.0 0.097 12.7 0.0 1.5 1 0 0 1 1 1 0 Radical_SAM C-terminal domain ATP-synt_ab PF00006.25 EPS26209.1 - 8.6e-66 221.6 0.0 1.3e-65 221.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 EPS26209.1 - 3.3e-43 146.4 0.0 5.5e-43 145.7 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 EPS26209.1 - 9e-14 51.8 0.7 1.9e-13 50.7 0.7 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain SBDS PF01172.18 EPS26211.1 - 2.4e-22 78.8 0.0 2.9e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein DUF4776 PF16003.5 EPS26212.1 - 0.0074 15.3 1.6 0.0085 15.1 1.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4776) Pex19 PF04614.12 EPS26212.1 - 0.015 15.1 0.2 0.018 14.8 0.2 1.0 1 0 0 1 1 1 0 Pex19 protein family HrpJ PF07201.11 EPS26212.1 - 0.024 14.9 2.8 0.032 14.5 2.8 1.2 1 0 0 1 1 1 0 HrpJ-like domain pEK499_p136 PF18736.1 EPS26212.1 - 0.052 13.2 0.9 0.066 12.8 0.9 1.1 1 0 0 1 1 1 0 HEPN pEK499 p136 DUF5595 PF18077.1 EPS26212.1 - 0.095 12.8 2.0 0.17 12.0 2.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) DUF4407 PF14362.6 EPS26212.1 - 0.24 10.7 2.2 0.29 10.4 2.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_11 PF13086.6 EPS26212.1 - 0.26 11.1 4.0 0.29 10.9 4.0 1.0 1 0 0 1 1 1 0 AAA domain Radial_spoke_3 PF06098.11 EPS26212.1 - 5.9 6.1 13.8 0.93 8.7 9.6 1.6 1 1 0 1 1 1 0 Radial spoke protein 3 PRT_C PF08372.10 EPS26213.1 - 0.12 12.1 1.3 0.52 10.0 0.2 2.3 2 1 1 3 3 3 0 Plant phosphoribosyltransferase C-terminal RRP36 PF06102.12 EPS26217.1 - 1.3e-47 161.8 29.2 1.3e-47 161.8 29.2 2.4 2 1 1 3 3 3 1 rRNA biogenesis protein RRP36 NIF PF03031.18 EPS26218.1 - 3.4e-25 88.6 0.8 2.1e-24 86.1 0.8 2.0 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase SOCS PF12610.8 EPS26218.1 - 0.13 12.6 0.7 2.1 8.8 0.0 2.8 2 0 0 2 2 2 0 Suppressor of cytokine signalling EF1G PF00647.19 EPS26219.1 - 6.5e-45 151.6 0.0 1.3e-44 150.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 EPS26219.1 - 3.5e-15 56.0 0.1 8.7e-15 54.7 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EPS26219.1 - 9.1e-11 41.9 0.0 2.2e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EPS26219.1 - 1e-08 35.0 0.0 2.6e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EPS26219.1 - 5.2e-06 26.6 0.0 1.3e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EPS26219.1 - 0.00091 19.6 0.0 0.0019 18.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain OAD_gamma PF04277.13 EPS26219.1 - 1 10.0 3.8 2.9 8.6 2.1 2.4 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Ribosomal_60s PF00428.19 EPS26219.1 - 8.2 7.1 11.7 5.9 7.5 9.0 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein Ribosomal_S9 PF00380.19 EPS26220.1 - 3.1e-39 134.2 0.8 4.8e-39 133.6 0.8 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 EF-hand_1 PF00036.32 EPS26223.1 - 6.1e-28 94.3 11.0 1.6e-08 33.5 0.5 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EPS26223.1 - 5.2e-22 78.1 13.1 9.1e-14 51.7 1.1 2.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EPS26223.1 - 7.9e-21 72.2 6.5 6.9e-05 22.5 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EPS26223.1 - 2.4e-19 67.9 9.6 4.8e-07 29.0 0.4 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EPS26223.1 - 2e-13 49.9 9.6 9.1e-05 22.2 0.5 4.0 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EPS26223.1 - 1.3e-06 28.7 0.0 0.0084 16.4 0.0 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EPS26223.1 - 0.00016 21.5 7.6 0.44 10.5 0.3 4.0 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EPS26223.1 - 0.016 15.6 0.1 0.4 11.1 0.1 2.7 2 1 1 3 3 3 0 EF-hand domain EPL1 PF10513.9 EPS26224.1 - 1.8e-24 86.9 0.7 1.8e-24 86.9 0.7 2.9 3 1 0 3 3 3 1 Enhancer of polycomb-like SET PF00856.28 EPS26225.1 - 1.5e-21 77.5 0.0 3.7e-21 76.2 0.0 1.6 2 0 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 EPS26225.1 - 6e-11 43.1 1.4 1.9e-10 41.5 0.1 2.3 3 0 0 3 3 3 1 Rubisco LSMT substrate-binding Peptidase_M22 PF00814.25 EPS26226.1 - 1.9e-86 290.1 0.0 2.2e-86 289.9 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 EPS26226.1 - 0.1 12.2 0.0 0.83 9.2 0.0 2.0 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus AMPK1_CBM PF16561.5 EPS26227.1 - 2.8e-29 101.2 0.1 4.8e-29 100.4 0.1 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 EPS26227.1 - 2.4e-25 88.6 2.0 8.1e-25 86.9 2.0 2.0 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain Pho86 PF11124.8 EPS26228.1 - 0.0098 15.4 1.0 0.011 15.3 1.0 1.1 1 0 0 1 1 1 1 Inorganic phosphate transporter Pho86 Phage_Coat_Gp8 PF05371.12 EPS26228.1 - 1 9.2 3.9 1.4 8.8 0.1 2.7 2 1 1 3 3 3 0 Phage major coat protein, Gp8 Cupin_2 PF07883.11 EPS26229.1 - 5.7e-10 38.8 0.0 8.1e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 EPS26229.1 - 0.0063 16.1 0.0 0.0081 15.8 0.0 1.2 1 0 0 1 1 1 1 Cupin CENP-C_C PF11699.8 EPS26229.1 - 0.04 14.1 0.0 0.049 13.8 0.0 1.2 1 0 0 1 1 1 0 Mif2/CENP-C like DMSP_lyase PF16867.5 EPS26229.1 - 0.081 12.6 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase ADH_zinc_N_2 PF13602.6 EPS26230.1 - 1.2e-21 78.1 0.1 2.1e-21 77.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EPS26230.1 - 3.1e-13 49.9 0.0 5.4e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPS26230.1 - 0.00037 20.4 0.0 0.0066 16.3 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.24 EPS26230.1 - 0.00041 20.8 0.1 0.00074 19.9 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 EPS26230.1 - 0.00091 19.3 0.0 0.0016 18.6 0.0 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 EPS26230.1 - 0.019 14.4 0.1 0.029 13.8 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EPS26230.1 - 0.022 13.9 0.2 0.079 12.0 0.0 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain TrkA_N PF02254.18 EPS26230.1 - 0.032 14.5 0.1 0.065 13.5 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain adh_short PF00106.25 EPS26230.1 - 0.065 12.7 0.1 0.1 12.0 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Fungal_trans_2 PF11951.8 EPS26231.1 - 0.00064 18.6 0.1 0.00091 18.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS26231.1 - 0.0016 18.5 11.4 0.0029 17.7 11.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fanconi_A PF03511.14 EPS26231.1 - 0.011 15.7 0.0 0.032 14.2 0.0 1.7 1 0 0 1 1 1 0 Fanconi anaemia group A protein Glyco_hydro_18 PF00704.28 EPS26232.1 - 9.7e-24 84.6 0.2 1.5e-23 84.0 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 COesterase PF00135.28 EPS26233.1 - 6.6e-57 193.5 0.0 1.2e-50 172.8 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EPS26233.1 - 7.5e-07 29.2 0.0 1.4e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 EPS26233.1 - 0.012 15.2 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold mRNA_cap_enzyme PF01331.19 EPS26234.1 - 1.3e-52 178.5 0.3 1.7e-52 178.1 0.3 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 EPS26234.1 - 5e-35 120.4 0.1 1.1e-34 119.3 0.1 1.6 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 EPS26234.1 - 2.9e-08 33.6 0.1 2.6e-06 27.2 0.1 2.4 1 1 1 2 2 2 2 ATP dependent DNA ligase domain RNA_ligase PF09414.10 EPS26234.1 - 0.0029 17.9 0.1 0.019 15.2 0.0 2.0 2 0 0 2 2 2 1 RNA ligase SCA7 PF08313.12 EPS26236.1 - 2.9e-31 107.1 2.0 8.8e-31 105.6 2.0 1.9 1 0 0 1 1 1 1 SCA7, zinc-binding domain zf_C2H2_13 PF18508.1 EPS26236.1 - 0.029 14.0 0.6 0.075 12.6 0.6 1.7 1 0 0 1 1 1 0 Zinc finger domain CDC45 PF02724.14 EPS26236.1 - 1.3 7.2 11.9 1.9 6.7 11.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 EPS26236.1 - 1.9 7.2 4.4 2.7 6.7 4.4 1.4 1 0 0 1 1 1 0 Presenilin DUF2151 PF10221.9 EPS26236.1 - 4.1 5.9 6.5 6.7 5.2 6.5 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator OrsD PF12013.8 EPS26236.1 - 6.5 7.2 6.9 1.1 9.7 0.9 2.4 1 1 1 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D ketoacyl-synt PF00109.26 EPS26237.1 - 4.1e-60 203.5 3.1 4.4e-60 203.4 0.5 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EPS26237.1 - 2.7e-33 114.5 3.0 3.6e-33 114.1 1.4 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EPS26237.1 - 9e-06 25.2 1.0 5.8e-05 22.6 0.1 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EPS26237.1 - 0.022 14.4 2.7 0.047 13.4 0.3 2.6 3 0 0 3 3 3 0 Thiolase, C-terminal domain Arginase PF00491.21 EPS26238.1 - 8.3e-93 310.9 0.0 1e-92 310.6 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 EPS26238.1 - 0.0023 18.2 0.0 0.0044 17.3 0.0 1.4 1 0 0 1 1 1 1 UPF0489 domain Ras PF00071.22 EPS26239.1 - 1.4e-52 177.6 0.0 1.6e-52 177.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EPS26239.1 - 7e-19 68.2 0.0 9.5e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPS26239.1 - 1.4e-06 27.9 0.0 1.8e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MFS_1 PF07690.16 EPS26241.1 - 7.8e-20 71.1 42.4 3.7e-19 68.9 40.7 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF5357 PF17310.2 EPS26241.1 - 0.027 13.1 0.2 0.068 11.7 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5357) DUF1349 PF07081.11 EPS26242.1 - 3.8e-31 108.2 0.0 4.6e-31 107.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) Zip PF02535.22 EPS26244.1 - 0.26 10.5 2.2 0.3 10.3 2.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Hydin_ADK PF17213.3 EPS26244.1 - 1.1 9.5 3.2 1.9 8.7 3.2 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DUF2753 PF10952.8 EPS26247.1 - 0.11 12.6 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2753) Pyridoxal_deC PF00282.19 EPS26248.1 - 3.2e-50 170.9 0.0 4.2e-50 170.5 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.21 EPS26248.1 - 0.00011 21.5 0.0 0.00019 20.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EPS26248.1 - 0.00013 21.1 0.0 0.00019 20.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V AMP-binding PF00501.28 EPS26249.1 - 1.5e-75 254.4 0.0 2e-75 254.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EPS26249.1 - 1.5e-33 116.1 0.0 3.1e-33 115.0 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein AMP-binding_C PF13193.6 EPS26249.1 - 2.5e-05 25.2 0.0 5.9e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.21 EPS26249.1 - 0.037 13.5 0.0 0.18 11.2 0.0 2.2 3 1 0 3 3 3 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 EPS26250.1 - 9.1e-25 87.3 0.0 2.3e-23 82.7 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS26250.1 - 4.6e-11 42.7 0.0 1e-09 38.3 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPS26250.1 - 2.8e-09 37.1 0.0 5.2e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPS26250.1 - 0.00036 20.1 0.1 0.001 18.6 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EPS26250.1 - 0.00058 19.1 0.0 0.0011 18.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GTP1_OBG PF01018.22 EPS26250.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 GTP1/OBG MFS_1 PF07690.16 EPS26251.1 - 2.2e-32 112.4 86.0 1.7e-29 102.9 64.5 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS26251.1 - 4.5e-05 22.5 38.1 0.0049 15.8 11.7 3.4 2 2 0 2 2 2 2 Sugar (and other) transporter DIT1_PvcA PF05141.12 EPS26252.1 - 6.7e-58 196.3 0.0 1.8e-55 188.4 0.0 2.2 1 1 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.16 EPS26252.1 - 4.8e-28 98.7 0.3 1.1e-27 97.5 0.3 1.6 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF3510 PF12022.8 EPS26252.1 - 0.13 12.6 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) Hydrolase_6 PF13344.6 EPS26253.1 - 1.1e-30 105.8 0.0 1.8e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EPS26253.1 - 1.6e-17 63.3 0.0 3e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 EPS26253.1 - 9.8e-06 25.8 0.8 0.0011 19.1 0.0 2.5 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EPS26253.1 - 2.5e-05 24.7 0.0 5.8e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Peripla_BP_4 PF13407.6 EPS26253.1 - 0.079 12.5 0.1 0.4 10.2 0.0 2.1 2 1 1 3 3 3 0 Periplasmic binding protein domain Acid_phosphat_B PF03767.14 EPS26253.1 - 0.15 11.6 0.0 0.39 10.3 0.0 1.6 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) MDMPI_C PF07398.11 EPS26254.1 - 0.09 13.6 0.2 0.29 12.0 0.1 2.0 2 0 0 2 2 2 0 MDMPI C-terminal domain DJ-1_PfpI PF01965.24 EPS26255.1 - 6.5e-22 78.1 0.0 7.7e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family APC_u5 PF16630.5 EPS26256.1 - 0.13 13.3 1.3 0.27 12.3 1.3 1.4 1 0 0 1 1 1 0 Unstructured region on APC between 1st and 2nd catenin-bdg motifs Serglycin PF04360.12 EPS26256.1 - 1.1 9.2 7.3 0.075 13.0 2.2 1.6 2 0 0 2 2 2 0 Serglycin DIT1_PvcA PF05141.12 EPS26257.1 - 7.4e-79 265.1 0.0 1.1e-78 264.6 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein GST_N PF02798.20 EPS26258.1 - 3.3e-13 49.8 0.0 6.9e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EPS26258.1 - 1e-09 38.6 0.0 2e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EPS26258.1 - 1.1e-09 38.1 0.0 2.1e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EPS26258.1 - 5.2e-09 36.2 0.0 1e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EPS26258.1 - 7.9e-09 35.7 0.0 1.8e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EPS26258.1 - 4.4e-07 30.0 0.0 1.7e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Trp_halogenase PF04820.14 EPS26259.1 - 4.7e-13 48.8 0.1 1.3e-08 34.1 0.0 3.2 2 1 0 3 3 3 3 Tryptophan halogenase DAO PF01266.24 EPS26259.1 - 0.0013 18.4 0.2 0.0037 16.9 0.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EPS26259.1 - 0.0056 16.9 0.0 0.017 15.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EPS26259.1 - 0.021 13.5 0.2 0.031 13.0 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_oxidored PF12831.7 EPS26259.1 - 0.044 13.1 0.0 0.068 12.5 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Zn_clus PF00172.18 EPS26260.1 - 2.8e-05 24.1 8.4 5e-05 23.3 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FlgN PF05130.12 EPS26260.1 - 0.013 16.0 0.2 0.028 14.9 0.2 1.5 1 0 0 1 1 1 0 FlgN protein p450 PF00067.22 EPS26262.1 - 2.7e-57 194.6 0.0 3.6e-57 194.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1910 PF08928.10 EPS26263.1 - 0.0037 17.2 0.4 0.011 15.8 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1910) COesterase PF00135.28 EPS26264.1 - 6.5e-83 279.3 0.0 8.7e-83 278.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EPS26264.1 - 1.2e-05 25.3 0.4 0.00012 22.0 0.4 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Alpha-amylase PF00128.24 EPS26265.1 - 5.3e-68 230.1 0.2 8.5e-68 229.4 0.2 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain CBM_20 PF00686.19 EPS26265.1 - 7.4e-33 112.3 0.2 2.3e-32 110.7 0.2 1.9 1 0 0 1 1 1 1 Starch binding domain DUF1966 PF09260.11 EPS26265.1 - 2.5e-32 111.0 1.5 7.1e-32 109.5 1.5 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) IreB PF06135.12 EPS26265.1 - 0.048 13.9 0.6 8.6 6.6 0.1 2.8 2 0 0 2 2 2 0 IreB regulatory phosphoprotein Aminotran_5 PF00266.19 EPS26265.1 - 0.058 12.3 0.1 0.17 10.8 0.0 1.7 2 0 0 2 2 2 0 Aminotransferase class-V PUMA PF15826.5 EPS26265.1 - 0.3 11.3 2.0 0.56 10.4 2.0 1.4 1 0 0 1 1 1 0 Bcl-2-binding component 3, p53 upregulated modulator of apoptosis ADH_N PF08240.12 EPS26266.1 - 7.3e-21 74.1 6.9 1.2e-20 73.4 6.9 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPS26266.1 - 1e-19 70.8 0.0 1.6e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPS26266.1 - 5.6e-09 37.2 0.0 1.8e-08 35.5 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EPS26266.1 - 0.00036 19.9 0.0 0.00057 19.2 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 EPS26266.1 - 0.004 17.4 0.0 0.0063 16.8 0.0 1.2 1 0 0 1 1 1 1 TrkA-N domain 2-Hacid_dh_C PF02826.19 EPS26266.1 - 0.0061 15.9 0.1 0.0097 15.3 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Gpr1_Fun34_YaaH PF01184.19 EPS26268.1 - 2.6e-14 53.3 18.7 3.5e-14 52.9 18.7 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family adh_short PF00106.25 EPS26269.1 - 1.4e-39 135.6 0.0 2e-39 135.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS26269.1 - 5.5e-28 98.1 0.0 7e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPS26269.1 - 4.5e-10 39.7 0.0 6e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPS26269.1 - 2e-07 30.7 0.0 1.1e-06 28.3 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EPS26269.1 - 0.00024 20.3 0.0 0.00035 19.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain DUF1776 PF08643.10 EPS26269.1 - 0.041 13.2 0.0 0.052 12.9 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NmrA PF05368.13 EPS26269.1 - 0.16 11.5 0.1 0.51 9.9 0.0 1.8 2 0 0 2 2 2 0 NmrA-like family DUF2406 PF10295.9 EPS26270.1 - 7.8e-26 90.5 0.1 1.4e-25 89.7 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) DUF3446 PF11928.8 EPS26270.1 - 0.23 11.8 4.0 0.31 11.4 4.0 1.3 1 0 0 1 1 1 0 Early growth response N-terminal domain Acyl-CoA_dh_1 PF00441.24 EPS26271.1 - 6.6e-33 114.0 1.5 1.3e-32 113.1 1.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EPS26271.1 - 6.7e-19 67.9 0.0 1.3e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EPS26271.1 - 7.6e-18 65.2 0.1 2.1e-17 63.8 0.1 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EPS26271.1 - 2e-14 54.0 4.3 2.5e-14 53.7 1.3 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Spc7_C2 PF15577.6 EPS26271.1 - 0.17 12.0 0.1 0.55 10.3 0.0 1.8 2 0 0 2 2 2 0 Spc7_C2 CoA_transf_3 PF02515.17 EPS26272.1 - 1.1e-108 363.7 0.0 1.3e-108 363.5 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Pyr_redox_2 PF07992.14 EPS26273.1 - 2.9e-30 105.5 0.0 3.9e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPS26273.1 - 1.4e-12 47.9 0.2 2.7e-11 43.9 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EPS26273.1 - 1.3e-07 31.2 0.0 2.4e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EPS26273.1 - 2.9e-06 26.7 0.1 6.5e-06 25.5 0.1 1.6 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.6 EPS26273.1 - 5.5e-05 23.6 0.0 0.001 19.4 0.0 2.7 3 0 0 3 3 3 1 Putative NAD(P)-binding NAD_binding_9 PF13454.6 EPS26273.1 - 6.8e-05 22.9 0.6 1.5 8.8 0.0 3.8 3 1 0 4 4 4 2 FAD-NAD(P)-binding DAO PF01266.24 EPS26273.1 - 0.00018 21.2 0.3 0.12 11.9 0.0 3.5 3 1 0 4 4 4 1 FAD dependent oxidoreductase TrkA_N PF02254.18 EPS26273.1 - 0.0023 18.2 0.6 0.16 12.3 0.0 3.0 3 0 0 3 3 3 1 TrkA-N domain NAD_binding_8 PF13450.6 EPS26273.1 - 0.0087 16.3 0.0 0.17 12.1 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Sacchrp_dh_NADP PF03435.18 EPS26273.1 - 0.025 14.8 0.1 4 7.7 0.0 2.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Trp_halogenase PF04820.14 EPS26273.1 - 0.044 12.6 0.0 0.17 10.7 0.0 2.0 3 0 0 3 3 3 0 Tryptophan halogenase DUF1188 PF06690.11 EPS26273.1 - 0.048 13.2 0.0 6.5 6.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) ApbA PF02558.16 EPS26273.1 - 0.13 11.9 0.1 1.2 8.8 0.0 2.7 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA SPA PF08616.10 EPS26274.1 - 0.03 14.3 0.0 0.036 14.0 0.0 1.1 1 0 0 1 1 1 0 Stabilization of polarity axis AA_permease PF00324.21 EPS26275.1 - 2.8e-91 306.5 39.1 3.3e-91 306.3 39.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EPS26275.1 - 1.5e-21 76.8 43.1 1.8e-21 76.5 43.1 1.0 1 0 0 1 1 1 1 Amino acid permease AMP-binding PF00501.28 EPS26276.1 - 0 1281.4 0.0 2.4e-77 260.3 0.0 7.4 6 1 0 6 6 6 6 AMP-binding enzyme Condensation PF00668.20 EPS26276.1 - 0 1036.9 0.0 1.4e-54 185.5 0.0 9.8 8 2 0 8 8 8 8 Condensation domain PP-binding PF00550.25 EPS26276.1 - 1.7e-74 246.1 12.6 7e-13 48.7 0.4 8.1 7 0 0 7 7 7 7 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EPS26276.1 - 4.1e-10 40.5 0.0 0.29 12.1 0.0 5.9 5 0 0 5 5 5 3 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.16 EPS26276.1 - 0.00038 20.3 0.7 14 5.3 0.0 4.9 6 0 0 6 6 6 2 Wax ester synthase-like Acyl-CoA acyltransferase domain Luciferase_N PF05295.11 EPS26276.1 - 0.11 12.5 0.6 4.5 7.4 0.0 3.8 4 0 0 4 4 4 0 Luciferase/LBP N-terminal domain NAT PF04768.13 EPS26277.1 - 1.6e-15 57.2 0.1 5.6e-15 55.4 0.0 1.9 2 1 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Ank_4 PF13637.6 EPS26278.1 - 1.4e-19 70.2 1.0 5e-13 49.3 0.3 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EPS26278.1 - 8.8e-19 67.9 0.5 1.3e-18 67.3 0.5 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EPS26278.1 - 1.1e-18 66.8 4.7 2e-06 28.0 0.2 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EPS26278.1 - 3.2e-15 56.0 2.4 9.4e-08 32.2 0.2 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPS26278.1 - 5.7e-15 53.9 1.7 9.9e-07 28.6 0.1 3.3 3 0 0 3 3 3 3 Ankyrin repeat Aminotran_4 PF01063.19 EPS26279.1 - 4.5e-28 98.6 0.0 5.4e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV p450 PF00067.22 EPS26280.1 - 1.8e-73 247.9 0.0 2.4e-73 247.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fas_alpha_ACP PF18325.1 EPS26281.1 - 8.4e-57 192.0 0.0 1.8e-56 190.9 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 EPS26281.1 - 8.9e-38 130.0 0.5 2.3e-37 128.6 0.0 1.9 2 0 0 2 2 2 1 Fatty acid synthase type I helical domain ketoacyl-synt PF00109.26 EPS26281.1 - 1.4e-19 70.7 2.4 1.6e-19 70.5 0.4 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EPS26281.1 - 1.7e-14 53.8 0.1 1.1e-13 51.3 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EPS26281.1 - 0.00075 18.9 0.1 0.002 17.6 0.1 1.8 1 0 0 1 1 1 1 Thiolase, N-terminal domain ABC_tran PF00005.27 EPS26282.1 - 1.8e-49 167.7 0.0 1.6e-28 99.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EPS26282.1 - 3.3e-36 125.4 24.4 1.7e-30 106.6 9.5 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_29 PF13555.6 EPS26282.1 - 2.4e-07 30.4 0.5 0.0056 16.4 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EPS26282.1 - 5.4e-07 30.0 0.5 0.0057 16.9 0.1 3.3 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EPS26282.1 - 5.5e-07 30.1 0.0 0.038 14.4 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 EPS26282.1 - 6.9e-07 28.9 3.4 0.00096 18.6 0.8 3.9 2 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EPS26282.1 - 8.7e-06 25.7 0.4 0.082 12.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_33 PF13671.6 EPS26282.1 - 1.2e-05 25.5 0.3 0.034 14.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EPS26282.1 - 0.00015 21.8 0.1 0.26 11.4 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF87 PF01935.17 EPS26282.1 - 0.0017 18.5 1.2 0.11 12.5 0.1 2.3 2 0 0 2 2 2 1 Helicase HerA, central domain RNA_helicase PF00910.22 EPS26282.1 - 0.0018 18.6 0.1 3.9 7.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 EPS26282.1 - 0.0028 17.2 0.1 1.5 8.3 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region NACHT PF05729.12 EPS26282.1 - 0.0028 17.6 0.3 2.7 7.9 0.0 2.9 3 0 0 3 3 2 1 NACHT domain AAA PF00004.29 EPS26282.1 - 0.0034 17.8 1.1 1.1 9.7 0.0 3.4 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.6 EPS26282.1 - 0.0036 17.2 0.1 9.6 5.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system Septin PF00735.18 EPS26282.1 - 0.0041 16.4 0.6 1.6 7.9 0.1 2.3 2 0 0 2 2 2 1 Septin ATP_bind_1 PF03029.17 EPS26282.1 - 0.0064 16.3 0.4 4 7.2 0.1 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein ATP-synt_ab PF00006.25 EPS26282.1 - 0.0065 16.1 0.1 1.3 8.6 0.0 2.6 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.14 EPS26282.1 - 0.0072 16.3 0.3 5.6 7.0 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 EPS26282.1 - 0.0073 15.9 0.2 1 8.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EPS26282.1 - 0.0074 16.8 0.0 6.4 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EPS26282.1 - 0.008 16.7 0.9 4.2 7.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EPS26282.1 - 0.0088 16.0 1.8 0.15 12.0 0.0 2.7 3 0 0 3 3 2 1 Rad17 P-loop domain NB-ARC PF00931.22 EPS26282.1 - 0.026 13.7 0.1 1.1 8.4 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Viral_helicase1 PF01443.18 EPS26282.1 - 0.026 14.3 0.1 2.7 7.7 0.0 3.1 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_15 PF13175.6 EPS26282.1 - 0.027 14.2 0.0 2.5 7.7 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain SbcCD_C PF13558.6 EPS26282.1 - 0.032 14.4 0.4 12 6.3 0.1 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit TsaE PF02367.17 EPS26282.1 - 0.053 13.5 0.0 1 9.4 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE E1_UFD PF09358.10 EPS26282.1 - 0.054 14.2 0.0 0.22 12.3 0.0 2.0 2 0 0 2 2 1 0 Ubiquitin fold domain cobW PF02492.19 EPS26282.1 - 0.057 13.0 2.5 2 8.0 0.2 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF815 PF05673.13 EPS26282.1 - 0.061 12.5 0.0 5 6.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 EPS26282.1 - 0.073 12.4 0.1 5 6.3 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.6 EPS26282.1 - 0.076 12.7 2.1 4.4 7.0 0.1 2.8 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 EPS26282.1 - 0.076 12.7 0.2 16 5.1 0.1 2.8 3 0 0 3 3 3 0 AAA domain NTPase_1 PF03266.15 EPS26282.1 - 0.083 12.8 0.9 2.7 7.9 0.0 2.4 2 0 0 2 2 2 0 NTPase MeaB PF03308.16 EPS26282.1 - 0.12 11.3 0.3 0.53 9.2 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 EPS26282.1 - 0.13 12.3 0.8 3.4 7.7 0.0 2.3 2 0 0 2 2 2 0 Dynamin family FtsK_SpoIIIE PF01580.18 EPS26282.1 - 0.13 11.6 2.7 2.9 7.2 0.1 2.5 3 0 0 3 3 2 0 FtsK/SpoIIIE family T2SSE PF00437.20 EPS26282.1 - 0.14 11.2 1.2 5.3 6.0 0.0 2.6 3 0 0 3 3 2 0 Type II/IV secretion system protein Roc PF08477.13 EPS26282.1 - 0.14 12.4 0.0 30 4.8 0.1 3.4 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase dNK PF01712.19 EPS26282.1 - 0.15 11.9 0.1 1.9 8.3 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase Mg_chelatase PF01078.21 EPS26282.1 - 0.15 11.4 0.0 1.9 7.8 0.0 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Adeno_IVa2 PF02456.15 EPS26282.1 - 0.18 10.6 0.3 2.3 6.9 0.1 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein Sigma54_activat PF00158.26 EPS26282.1 - 0.18 11.5 0.0 9 6.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain 4HBT_2 PF13279.6 EPS26283.1 - 3.5e-08 34.0 0.0 5e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF2811 PF10929.8 EPS26283.1 - 0.12 12.6 0.4 6.3 7.2 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2811) DUF1729 PF08354.10 EPS26284.1 - 3.3e-148 493.3 0.0 4.6e-148 492.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 EPS26284.1 - 6.8e-63 213.1 0.0 7.1e-62 209.7 0.0 2.5 3 0 0 3 3 3 1 Acyl transferase domain FAS_meander PF17951.1 EPS26284.1 - 6.2e-43 146.1 0.0 1.8e-42 144.6 0.0 1.8 2 0 0 2 2 2 1 Fatty acid synthase meander beta sheet domain SAT PF16073.5 EPS26284.1 - 8.7e-35 120.6 0.0 2.3e-34 119.2 0.0 1.7 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 EPS26284.1 - 1e-25 89.7 0.0 2.8e-25 88.3 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain FAS_N PF17828.1 EPS26284.1 - 1.2e-13 51.2 0.0 2.5e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydrat_N PF13452.6 EPS26284.1 - 3.5e-13 49.8 0.1 1.8e-12 47.5 0.1 2.2 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase RTA1 PF04479.13 EPS26285.1 - 6.5e-51 172.9 6.3 6.5e-51 172.9 6.3 1.3 2 0 0 2 2 2 1 RTA1 like protein DUF3007 PF11460.8 EPS26285.1 - 0.21 11.8 1.2 10 6.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) TMEM208_SND2 PF05620.11 EPS26285.1 - 2.6 7.8 6.7 0.81 9.5 0.1 2.6 2 1 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Ank_2 PF12796.7 EPS26286.1 - 3.8e-42 142.8 10.0 2.3e-18 66.5 0.5 3.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPS26286.1 - 5e-22 78.0 7.2 7.5e-10 39.1 0.1 3.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPS26286.1 - 1.8e-21 73.9 3.1 0.0039 17.6 0.0 5.4 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 EPS26286.1 - 5.5e-21 74.4 3.1 2e-06 28.0 0.1 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EPS26286.1 - 6.5e-21 73.8 13.4 3.7e-05 24.0 0.5 5.4 5 0 0 5 5 5 4 Ankyrin repeat bZIP_1 PF00170.21 EPS26286.1 - 0.23 11.6 5.0 0.4 10.8 5.0 1.3 1 0 0 1 1 1 0 bZIP transcription factor IHABP4_N PF16174.5 EPS26286.1 - 0.6 10.7 9.6 0.96 10.0 9.6 1.2 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Peptidase_S49_N PF08496.10 EPS26287.1 - 2.3 8.3 6.1 3.4 7.7 6.1 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal T3SS_needle_reg PF09025.10 EPS26289.1 - 0.092 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 YopR, type III needle-polymerisation regulator HSDR_N_2 PF13588.6 EPS26290.1 - 0.049 13.6 0.0 0.078 13.0 0.0 1.4 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) Pheromone PF08015.11 EPS26291.1 - 0.4 11.7 7.9 3.5 8.7 9.2 2.0 2 0 0 2 2 2 0 Fungal mating-type pheromone DUF3632 PF12311.8 EPS26292.1 - 9.1e-28 97.9 0.0 1.5e-27 97.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Antifungal_prot PF11402.8 EPS26293.1 - 5.8e-24 84.1 10.0 7.2e-24 83.8 10.0 1.1 1 0 0 1 1 1 1 Antifungal protein MFS_1 PF07690.16 EPS26294.1 - 9.5e-26 90.5 52.8 2.2e-17 63.1 24.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.18 EPS26295.1 - 7.3e-13 48.2 1.0 1.5e-12 47.1 1.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS26295.1 - 6.1e-09 35.9 10.2 1.2e-08 34.9 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HEPN_DZIP3 PF18738.1 EPS26295.1 - 0.14 11.9 0.2 0.44 10.3 0.0 1.8 2 0 0 2 2 2 0 DZIP3/ hRUL138-like HEPN FAD_binding_3 PF01494.19 EPS26297.1 - 9.6e-50 169.8 0.0 1.5e-49 169.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DprA_WH PF17782.1 EPS26297.1 - 0.072 13.2 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 DprA winged helix domain Fungal_trans PF04082.18 EPS26298.1 - 5.5e-09 35.4 2.5 5.5e-09 35.4 2.5 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS26298.1 - 3.6e-05 23.8 13.1 6.4e-05 23.0 13.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.28 EPS26299.1 - 7.6e-81 271.9 0.0 1.4e-80 270.9 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 EPS26299.1 - 1.9e-70 237.4 0.0 8e-70 235.3 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.20 EPS26299.1 - 1.1e-68 232.0 0.5 1.8e-68 231.3 0.5 1.2 1 0 0 1 1 1 1 Condensation domain KR PF08659.10 EPS26299.1 - 2.2e-51 174.3 1.3 1.8e-50 171.3 0.1 2.8 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 EPS26299.1 - 5.3e-49 167.1 0.6 9.4e-49 166.2 0.6 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 EPS26299.1 - 2e-47 162.3 0.0 4.6e-47 161.1 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EPS26299.1 - 9.9e-29 99.8 0.0 2.6e-28 98.4 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 EPS26299.1 - 2.3e-23 82.7 0.0 1.1e-21 77.1 0.0 2.5 1 1 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.12 EPS26299.1 - 1.7e-20 73.6 0.0 5.8e-20 71.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EPS26299.1 - 1.3e-16 61.0 0.0 3.4e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 EPS26299.1 - 2.3e-15 56.7 0.2 3.5e-06 27.3 0.1 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site adh_short PF00106.25 EPS26299.1 - 3.5e-14 52.7 0.1 3.2e-12 46.3 0.1 2.8 2 0 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.21 EPS26299.1 - 4.2e-13 49.3 0.0 5.5e-10 39.1 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.6 EPS26299.1 - 5.6e-11 43.0 0.1 4.9e-10 40.0 0.0 2.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPS26299.1 - 6.6e-10 39.0 0.0 2.5e-09 37.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS26299.1 - 5.9e-09 36.5 0.1 4.6e-08 33.6 0.0 2.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPS26299.1 - 1e-08 35.2 0.0 2.5e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.19 EPS26299.1 - 5.4e-08 32.2 0.0 9.7e-07 28.1 0.0 2.2 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short_C2 PF13561.6 EPS26299.1 - 2.3e-07 30.6 0.1 9.9e-07 28.5 0.1 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 EPS26299.1 - 1.1e-05 24.9 0.1 2.6e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain AMP-binding_C PF13193.6 EPS26299.1 - 1.4e-05 25.9 0.1 6.2e-05 23.9 0.0 2.3 2 0 0 2 2 1 1 AMP-binding enzyme C-terminal domain Ubie_methyltran PF01209.18 EPS26299.1 - 2.1e-05 24.0 0.0 4.1e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Glyco_hydro_42M PF08532.10 EPS26299.1 - 0.056 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Beta-galactosidase trimerisation domain Methyltransf_16 PF10294.9 EPS26299.1 - 0.062 13.0 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase Sacchrp_dh_NADP PF03435.18 EPS26299.1 - 0.095 13.0 0.0 5.7 7.2 0.0 3.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain p450 PF00067.22 EPS26300.1 - 1.6e-35 122.7 0.0 2e-35 122.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EPS26301.1 - 8e-28 97.4 0.0 2.6e-27 95.7 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Mon1 PF03164.14 EPS26301.1 - 0.14 11.2 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Trafficking protein Mon1 TetR_C_28 PF17937.1 EPS26301.1 - 0.19 12.2 0.0 10 6.7 0.0 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain ADH_zinc_N PF00107.26 EPS26302.1 - 6.1e-08 32.7 0.0 5.9e-07 29.5 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPS26302.1 - 6.5e-06 26.0 0.1 0.00039 20.3 0.0 2.9 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EPS26302.1 - 0.047 13.6 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase MFS_1 PF07690.16 EPS26303.1 - 2e-24 86.2 58.1 1.4e-18 67.0 31.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.18 EPS26304.1 - 0.24 11.5 15.8 0.49 10.6 15.8 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EPS26305.1 - 5.3e-41 140.7 48.0 5.6e-39 134.1 47.3 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EPS26305.1 - 1.5e-13 50.1 23.8 6.5e-13 48.0 23.6 1.9 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EPS26305.1 - 4.5 5.4 18.3 0.034 12.4 2.9 3.0 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family adh_short PF00106.25 EPS26306.1 - 3e-25 88.8 0.0 1.4e-18 67.1 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EPS26306.1 - 4e-12 46.2 0.0 1.6e-07 31.1 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPS26306.1 - 3.3e-05 23.9 0.1 5.5e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 KR domain Polyketide_cyc PF03364.20 EPS26307.1 - 0.00012 22.3 0.6 0.00031 21.0 0.6 1.8 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 EPS26307.1 - 0.00035 20.8 3.4 0.00084 19.6 3.4 1.8 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport CENP-B_dimeris PF09026.10 EPS26309.1 - 0.029 14.8 6.0 0.034 14.5 6.0 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Uso1_p115_C PF04871.13 EPS26309.1 - 0.85 10.0 5.9 1.1 9.7 5.9 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Glycos_transf_1 PF00534.20 EPS26311.1 - 1.6e-10 40.8 0.0 2.9e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EPS26311.1 - 1e-06 29.2 0.0 2.1e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Enolase_C PF00113.22 EPS26312.1 - 1.1e-41 143.0 0.0 1.8e-40 139.1 0.0 1.9 1 1 0 1 1 1 1 Enolase, C-terminal TIM barrel domain PSDC PF12588.8 EPS26313.1 - 4.2e-60 201.8 0.0 6.2e-60 201.2 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 EPS26313.1 - 1.6e-37 129.0 0.0 1.1e-36 126.3 0.0 1.9 2 0 0 2 2 2 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.6 EPS26313.1 - 0.016 15.0 1.0 0.69 9.8 0.1 2.4 2 0 0 2 2 2 0 Biotin-lipoyl like Peptidase_M23 PF01551.22 EPS26313.1 - 0.099 12.9 0.4 0.24 11.6 0.0 1.9 2 0 0 2 2 2 0 Peptidase family M23 Biotin_lipoyl PF00364.22 EPS26313.1 - 0.12 12.3 0.7 0.26 11.1 0.1 1.9 2 0 0 2 2 2 0 Biotin-requiring enzyme AAA_16 PF13191.6 EPS26315.1 - 0.004 17.6 0.3 0.019 15.3 0.3 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 EPS26315.1 - 0.066 13.4 0.0 0.39 10.9 0.0 2.5 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EPS26315.1 - 0.18 12.1 0.3 1.1 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain Augurin PF15187.6 EPS26315.1 - 0.25 11.5 1.6 0.64 10.2 0.2 2.2 2 0 0 2 2 2 0 Oesophageal cancer-related gene 4 Abhydrolase_6 PF12697.7 EPS26318.1 - 1.9e-16 61.4 3.9 2.6e-16 60.9 3.9 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EPS26318.1 - 7.8e-16 58.5 0.0 9.8e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EPS26318.1 - 9.4e-14 51.3 0.0 1.3e-13 50.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 EPS26318.1 - 0.058 13.2 0.0 0.076 12.9 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ndr PF03096.14 EPS26318.1 - 0.07 11.8 0.0 0.5 9.0 0.0 1.9 2 0 0 2 2 2 0 Ndr family Glyco_hydro_75 PF07335.11 EPS26319.1 - 5.5e-64 215.3 0.4 7.6e-64 214.9 0.4 1.2 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 Glyco_hydro_76 PF03663.14 EPS26320.1 - 7.4e-145 483.1 26.6 8.5e-145 482.9 26.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Cloacin_immun PF03513.14 EPS26320.1 - 0.044 14.1 0.1 0.12 12.7 0.1 1.8 1 0 0 1 1 1 0 Cloacin immunity protein MFS_1 PF07690.16 EPS26321.1 - 1.9e-31 109.3 28.9 1.9e-31 109.3 28.9 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily MASE2 PF05230.11 EPS26321.1 - 0.18 11.9 4.2 5.9 7.0 0.8 3.0 2 0 0 2 2 2 0 MASE2 domain Fungal_trans PF04082.18 EPS26322.1 - 3.5e-08 32.8 0.1 8.2e-08 31.6 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS26322.1 - 3.6e-08 33.4 13.0 7.3e-08 32.4 13.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Unpaired PF15972.5 EPS26322.1 - 0.13 11.8 0.3 0.34 10.4 0.3 1.7 1 0 0 1 1 1 0 Unpaired protein ABC2_membrane PF01061.24 EPS26323.1 - 1e-78 263.5 52.3 1e-44 152.5 20.5 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EPS26323.1 - 3e-41 141.1 0.0 3.8e-19 69.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EPS26323.1 - 9.8e-25 86.3 4.7 3.1e-22 78.3 0.0 3.2 3 0 0 3 3 2 2 CDR ABC transporter AAA_16 PF13191.6 EPS26323.1 - 4.4e-08 33.7 0.1 0.00011 22.6 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 EPS26323.1 - 2.4e-07 30.9 0.0 0.29 10.9 0.0 3.6 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 EPS26323.1 - 1.7e-06 27.4 30.6 3.6e-06 26.3 8.4 2.9 3 1 1 4 4 4 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 EPS26323.1 - 6.9e-05 22.8 0.0 0.0011 18.9 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 EPS26323.1 - 0.0002 21.1 0.0 0.75 9.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 EPS26323.1 - 0.00052 20.3 0.1 0.078 13.2 0.1 3.3 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 EPS26323.1 - 0.00055 19.9 0.1 0.5 10.3 0.0 2.7 3 0 0 3 3 2 2 NACHT domain AAA_18 PF13238.6 EPS26323.1 - 0.00067 20.2 0.0 0.16 12.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EPS26323.1 - 0.00074 19.2 0.4 0.025 14.3 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_19 PF13245.6 EPS26323.1 - 0.00097 19.5 0.0 0.14 12.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EPS26323.1 - 0.0039 17.5 0.0 0.17 12.1 0.1 2.9 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.19 EPS26323.1 - 0.0047 16.4 0.0 1.8 8.0 0.0 3.2 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 EPS26323.1 - 0.016 14.8 0.0 0.061 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EPS26323.1 - 0.068 12.9 0.1 3.5 7.4 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Rad17 PF03215.15 EPS26323.1 - 0.099 12.6 0.0 11 5.9 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_33 PF13671.6 EPS26323.1 - 0.1 12.8 0.1 0.38 10.9 0.1 2.0 2 0 0 2 2 1 0 AAA domain cobW PF02492.19 EPS26323.1 - 0.16 11.5 0.0 1.7 8.2 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain EOS1 PF12326.8 EPS26323.1 - 0.16 11.9 2.3 0.35 10.8 2.3 1.5 1 0 0 1 1 1 0 N-glycosylation protein AAA_23 PF13476.6 EPS26323.1 - 0.19 12.2 0.0 0.36 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain NPP1 PF05630.11 EPS26324.1 - 2.4e-63 213.8 0.0 2.8e-63 213.6 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Glyco_hydro_61 PF03443.14 EPS26325.1 - 2.7e-69 233.2 0.0 4.1e-69 232.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.18 EPS26325.1 - 1.4e-11 44.2 9.4 1.4e-11 44.2 9.4 2.0 2 0 0 2 2 2 1 Fungal cellulose binding domain LapA_dom PF06305.11 EPS26326.1 - 0.26 11.1 0.7 0.59 10.0 0.7 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Glyco_transf_90 PF05686.12 EPS26328.1 - 2.3e-12 46.5 0.0 4.9e-12 45.5 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferase family 90 Na_H_Exchanger PF00999.21 EPS26329.1 - 3.3e-59 200.6 51.6 4.6e-59 200.1 51.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Sugar_tr PF00083.24 EPS26332.1 - 6.3e-83 279.1 20.3 7.7e-83 278.8 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS26332.1 - 4.4e-17 62.0 22.9 4.4e-17 62.0 22.9 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2456 PF10445.9 EPS26332.1 - 0.22 11.6 5.7 1.8 8.7 0.4 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2456) DUF4646 PF15496.6 EPS26333.1 - 1.1e-08 35.7 0.3 1.3e-07 32.2 0.0 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4646) Erf4 PF10256.9 EPS26333.1 - 0.00035 20.7 0.0 0.00088 19.4 0.0 1.7 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family CoA_binding_3 PF13727.6 EPS26333.1 - 0.043 13.8 0.0 0.061 13.3 0.0 1.2 1 0 0 1 1 1 0 CoA-binding domain ISN1 PF06437.11 EPS26334.1 - 6.5e-199 661.0 0.0 7.3e-199 660.8 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase PFK PF00365.20 EPS26335.1 - 8.5e-191 632.3 1.2 1.9e-104 349.0 0.2 2.1 2 0 0 2 2 2 2 Phosphofructokinase DAGK_cat PF00781.24 EPS26335.1 - 0.042 13.5 0.1 0.18 11.4 0.1 2.1 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain PAP2 PF01569.21 EPS26336.1 - 5.5e-26 91.0 1.0 5.5e-26 91.0 1.0 1.8 2 0 0 2 2 2 1 PAP2 superfamily Sulf_transp PF04143.14 EPS26336.1 - 0.0008 19.1 1.3 0.0011 18.6 0.2 1.7 2 0 0 2 2 2 1 Sulphur transport DUF2157 PF09925.9 EPS26336.1 - 0.1 12.4 2.8 1.8 8.3 0.1 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF4231 PF14015.6 EPS26336.1 - 0.15 12.5 0.5 8.6 6.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DAO PF01266.24 EPS26337.1 - 6.1e-37 128.0 0.3 7.1e-37 127.8 0.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EPS26337.1 - 0.00015 21.9 0.8 0.00053 20.2 0.4 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EPS26337.1 - 0.00075 19.5 0.2 0.023 14.7 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 EPS26337.1 - 0.0013 18.0 0.1 0.0022 17.3 0.1 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 EPS26337.1 - 0.061 12.6 0.0 0.097 11.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EPS26337.1 - 0.092 12.0 0.0 0.32 10.2 0.0 1.8 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Semialdhyde_dh PF01118.24 EPS26337.1 - 0.11 13.0 0.1 0.21 12.0 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 EPS26337.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein MFS_1 PF07690.16 EPS26339.1 - 2.8e-35 121.9 28.5 2.8e-35 121.9 28.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily LapA_dom PF06305.11 EPS26339.1 - 4.3 7.2 6.1 2.1 8.2 0.1 3.2 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Med17 PF10156.9 EPS26340.1 - 6.7e-97 325.1 0.0 9.8e-97 324.5 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Glyco_hydro_1 PF00232.18 EPS26341.1 - 1e-70 238.4 0.1 1e-36 126.3 0.1 3.1 2 1 0 2 2 2 2 Glycosyl hydrolase family 1 ADH_N PF08240.12 EPS26342.1 - 5.4e-24 84.2 0.0 1.4e-23 82.9 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPS26342.1 - 1.8e-18 66.8 0.6 3.2e-18 66.0 0.6 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPS26342.1 - 0.0013 19.7 0.0 0.0024 18.9 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glyco_hydro_76 PF03663.14 EPS26343.1 - 6.5e-165 549.1 24.9 7.6e-165 548.8 24.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 EPS26343.1 - 1.6e-05 24.2 10.4 0.004 16.3 0.0 3.3 2 1 1 3 3 3 3 Glycosyl Hydrolase Family 88 Ig_GlcNase PF18368.1 EPS26344.1 - 1.7e-31 108.5 1.0 1.7e-31 108.5 1.0 3.0 4 0 0 4 4 4 1 Exo-beta-D-glucosaminidase Ig-fold domain Glyco_hydro_2 PF00703.21 EPS26344.1 - 1.5e-12 48.2 2.9 6.4e-12 46.1 0.1 2.9 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Mannosidase_ig PF17786.1 EPS26344.1 - 4.4e-07 30.4 0.4 1.2e-06 29.0 0.4 1.8 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Ig_mannosidase PF17753.1 EPS26344.1 - 0.00013 21.7 0.3 0.0042 16.8 0.2 2.8 2 0 0 2 2 2 1 Ig-fold domain Glyco_hydro_2_N PF02837.18 EPS26344.1 - 0.002 18.1 0.1 0.0062 16.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 EPS26344.1 - 0.005 16.0 0.0 0.0086 15.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain ASH PF15780.5 EPS26344.1 - 0.19 12.0 2.0 11 6.4 0.3 3.0 3 0 0 3 3 3 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Pox_G7 PF05503.12 EPS26345.1 - 0.015 14.3 0.5 0.03 13.3 0.4 1.5 1 1 0 1 1 1 0 Poxvirus G7-like COesterase PF00135.28 EPS26346.1 - 2.9e-84 283.8 0.0 3.3e-84 283.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EPS26346.1 - 1.4e-05 25.0 0.2 3.5e-05 23.7 0.1 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EPS26346.1 - 0.00015 21.3 0.1 0.00024 20.7 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family SelP_N PF04592.14 EPS26348.1 - 0.44 9.9 5.6 0.51 9.7 5.6 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Dicty_REP PF05086.12 EPS26348.1 - 8.8 4.2 10.2 8.9 4.1 10.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Amidohydro_1 PF01979.20 EPS26349.1 - 4e-71 240.1 0.2 4.8e-71 239.9 0.2 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EPS26349.1 - 6e-20 72.2 2.3 5.1e-16 59.2 0.2 2.1 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 EPS26349.1 - 0.0067 15.8 0.0 0.014 14.8 0.0 1.4 2 0 0 2 2 2 1 Adenosine/AMP deaminase Glyco_hydro_88 PF07470.13 EPS26350.1 - 1.7e-97 326.6 1.7 1.9e-97 326.4 1.7 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_127 PF07944.12 EPS26350.1 - 0.00028 19.5 0.1 0.00036 19.2 0.1 1.2 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 MFS_1 PF07690.16 EPS26351.1 - 1.4e-30 106.4 20.7 2.1e-30 105.8 20.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily NAD_binding_6 PF08030.12 EPS26352.1 - 8.8e-25 87.6 0.0 1.5e-24 86.9 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EPS26352.1 - 6.8e-22 77.9 13.8 1e-21 77.3 11.0 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EPS26352.1 - 2.9e-08 33.8 0.0 6e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 EPS26352.1 - 0.0002 22.0 0.0 0.0084 16.7 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Gaa1 PF04114.14 EPS26352.1 - 0.0079 15.3 5.6 0.011 14.8 5.6 1.2 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component Cyt_bd_oxida_II PF02322.15 EPS26352.1 - 0.19 11.1 12.9 0.052 12.9 8.2 2.1 1 1 1 2 2 2 0 Cytochrome bd terminal oxidase subunit II Corona_M PF01635.18 EPS26352.1 - 7.6 5.8 9.9 0.37 10.1 0.3 2.3 2 0 0 2 2 2 0 Coronavirus M matrix/glycoprotein Ribonuclease_3 PF00636.26 EPS26353.1 - 5.2e-38 129.9 0.0 9.6e-20 71.2 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EPS26353.1 - 4.6e-28 97.9 0.0 5.9e-12 45.9 0.1 3.9 2 2 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.14 EPS26353.1 - 3.8e-24 84.7 0.0 1e-23 83.3 0.0 1.8 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.31 EPS26353.1 - 9.5e-16 58.1 0.0 2.2e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EPS26353.1 - 4.8e-14 52.5 0.0 1.2e-13 51.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EPS26353.1 - 1.3e-08 35.0 0.0 5.1e-08 33.1 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zinc_ribbon_10 PF10058.9 EPS26354.1 - 1.4e-19 69.5 0.1 2.3e-19 68.8 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein PHY PF00360.20 EPS26357.1 - 1.2e-30 106.2 0.0 2.4e-30 105.2 0.0 1.4 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.26 EPS26357.1 - 2.1e-17 63.6 0.0 4.3e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EPS26357.1 - 2.5e-14 53.4 0.0 1.1e-13 51.4 0.0 2.2 1 1 0 1 1 1 1 Response regulator receiver domain GAF PF01590.26 EPS26357.1 - 4e-14 53.4 0.0 1.8e-13 51.3 0.0 2.2 1 0 0 1 1 1 1 GAF domain HisKA PF00512.25 EPS26357.1 - 1.9e-10 40.6 0.5 6.5e-10 38.9 0.5 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.11 EPS26357.1 - 4e-08 33.9 0.0 1.8e-07 31.8 0.0 2.3 2 0 0 2 2 2 1 PAS fold HATPase_c_3 PF13589.6 EPS26357.1 - 0.051 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase bZIP_1 PF00170.21 EPS26361.1 - 2.8e-10 40.1 4.7 5.7e-10 39.2 4.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor PRKG1_interact PF15898.5 EPS26361.1 - 0.054 14.4 0.3 0.054 14.4 0.3 2.2 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain Glutaredoxin2_C PF04399.13 EPS26361.1 - 0.13 12.1 0.1 0.23 11.3 0.1 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain bZIP_2 PF07716.15 EPS26361.1 - 0.62 10.2 12.1 0.87 9.7 9.4 2.4 2 1 1 3 3 3 0 Basic region leucine zipper Anoctamin PF04547.12 EPS26362.1 - 1.4e-119 399.9 2.8 1.7e-119 399.6 2.8 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel ECF_trnsprt PF12822.7 EPS26362.1 - 0.00039 20.6 0.6 0.058 13.5 0.0 3.0 2 1 0 2 2 2 1 ECF transporter, substrate-specific component Pex2_Pex12 PF04757.14 EPS26362.1 - 0.078 12.6 0.1 0.51 9.9 0.0 2.4 2 0 0 2 2 2 0 Pex2 / Pex12 amino terminal region Synaphin PF05835.12 EPS26362.1 - 1.9 8.8 9.8 1 9.6 3.8 2.7 2 0 0 2 2 2 0 Synaphin protein Acetyltransf_1 PF00583.25 EPS26363.1 - 5.4e-15 55.7 0.0 6.6e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EPS26363.1 - 1.5e-07 31.3 0.0 2.4e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EPS26363.1 - 7.8e-07 29.4 0.0 1.1e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EPS26363.1 - 8.1e-06 25.8 0.0 1.2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EPS26363.1 - 0.00045 20.9 0.0 0.00057 20.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EPS26363.1 - 0.034 14.3 0.0 0.13 12.4 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain OB_aCoA_assoc PF01796.17 EPS26363.1 - 0.12 12.4 0.2 0.27 11.3 0.2 1.5 1 0 0 1 1 1 0 DUF35 OB-fold domain, acyl-CoA-associated GRIP PF01465.20 EPS26364.1 - 2.1e-14 53.2 0.5 5.1e-14 51.9 0.5 1.8 1 0 0 1 1 1 1 GRIP domain Spc7 PF08317.11 EPS26364.1 - 9.6e-07 28.0 145.2 0.00067 18.6 16.2 8.2 2 2 6 8 8 8 4 Spc7 kinetochore protein GAS PF13851.6 EPS26364.1 - 2.2e-06 27.2 138.9 0.015 14.6 19.5 10.0 2 2 8 10 10 10 8 Growth-arrest specific micro-tubule binding Fez1 PF06818.15 EPS26364.1 - 2.2e-05 25.0 136.8 0.85 10.0 11.0 8.6 1 1 7 8 8 8 5 Fez1 MscS_porin PF12795.7 EPS26364.1 - 2.2e-05 24.1 133.8 0.011 15.2 10.0 7.9 3 2 4 8 8 8 5 Mechanosensitive ion channel porin domain Cnn_1N PF07989.11 EPS26364.1 - 0.00011 22.2 4.2 0.00011 22.2 4.2 11.9 6 4 5 11 11 10 1 Centrosomin N-terminal motif 1 DHR10 PF18595.1 EPS26364.1 - 0.00013 22.0 42.3 0.0012 18.9 25.5 11.4 5 2 6 11 11 11 3 Designed helical repeat protein 10 domain DUF1192 PF06698.11 EPS26364.1 - 0.00049 20.1 0.9 0.00049 20.1 0.9 10.5 9 2 3 12 12 8 1 Protein of unknown function (DUF1192) FH2 PF02181.23 EPS26364.1 - 0.00057 19.1 2.6 0.00057 19.1 2.6 7.2 3 2 3 7 7 7 2 Formin Homology 2 Domain Tup_N PF08581.10 EPS26364.1 - 0.00066 19.9 1.4 0.00066 19.9 1.4 11.0 7 3 4 12 12 12 2 Tup N-terminal HMMR_N PF15905.5 EPS26364.1 - 0.00074 19.1 24.0 0.00074 19.1 24.0 7.5 2 2 4 6 6 6 3 Hyaluronan mediated motility receptor N-terminal AAA_13 PF13166.6 EPS26364.1 - 0.0034 16.1 19.2 0.0034 16.1 19.2 5.3 2 2 3 5 5 5 2 AAA domain CALCOCO1 PF07888.11 EPS26364.1 - 0.0035 16.3 30.5 0.0035 16.3 30.5 6.5 2 2 3 6 6 6 2 Calcium binding and coiled-coil domain (CALCOCO1) like Leu_zip PF15294.6 EPS26364.1 - 0.0044 16.6 18.2 0.0044 16.6 18.2 7.1 2 2 4 7 7 6 1 Leucine zipper BRE1 PF08647.11 EPS26364.1 - 0.0057 16.7 12.3 0.0057 16.7 12.3 10.8 4 2 7 11 11 10 2 BRE1 E3 ubiquitin ligase Baculo_PEP_C PF04513.12 EPS26364.1 - 0.0098 15.9 41.7 5 7.2 2.2 7.6 4 2 2 6 6 6 1 Baculovirus polyhedron envelope protein, PEP, C terminus APG6_N PF17675.1 EPS26364.1 - 0.014 15.9 16.2 0.014 15.9 16.2 10.1 2 2 7 9 9 9 0 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 EPS26364.1 - 0.024 14.7 160.8 0.022 14.8 24.4 9.9 3 2 6 10 10 10 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 EPS26364.1 - 0.033 13.8 126.7 0.012 15.3 36.9 7.8 2 2 4 6 6 6 0 Intermediate filament protein YopE PF03545.13 EPS26364.1 - 0.07 13.3 0.1 1.1 9.5 0.0 3.1 2 0 0 2 2 2 0 Yersinia virulence determinant (YopE) FPP PF05911.11 EPS26364.1 - 0.084 11.1 131.2 0.022 13.0 20.1 6.2 2 2 4 6 6 6 0 Filament-like plant protein, long coiled-coil DUF1664 PF07889.12 EPS26364.1 - 0.091 12.8 79.9 0.15 12.1 2.4 9.9 4 3 7 11 11 11 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 EPS26364.1 - 0.13 12.8 50.7 7.6 7.1 0.9 10.6 7 3 3 10 10 10 0 Nucleopolyhedrovirus P10 protein EzrA PF06160.12 EPS26364.1 - 0.18 9.9 107.0 0.23 9.6 42.8 6.4 2 2 1 4 4 4 0 Septation ring formation regulator, EzrA Golgin_A5 PF09787.9 EPS26364.1 - 0.32 10.4 137.3 0.19 11.2 16.4 6.9 2 2 4 6 6 6 0 Golgin subfamily A member 5 DUF4201 PF13870.6 EPS26364.1 - 7.6 6.2 119.7 0.11 12.2 9.5 10.4 2 2 6 9 9 9 0 Domain of unknown function (DUF4201) cNMP_binding PF00027.29 EPS26365.1 - 2.9e-28 97.8 0.2 9.4e-18 64.1 0.0 5.4 4 1 1 5 5 5 3 Cyclic nucleotide-binding domain Patatin PF01734.22 EPS26365.1 - 6.5e-17 62.4 7.8 4.5e-16 59.6 5.8 2.7 2 1 0 2 2 2 1 Patatin-like phospholipase CE2_N PF17996.1 EPS26366.1 - 4.3e-21 75.0 0.0 9.6e-21 73.8 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate esterase 2 N-terminal Lipase_GDSL_2 PF13472.6 EPS26366.1 - 1.3e-14 55.0 1.1 2.4e-14 54.1 1.1 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family CBM_1 PF00734.18 EPS26366.1 - 2.2e-11 43.5 13.0 5.5e-11 42.2 13.0 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain Lipase_GDSL PF00657.22 EPS26366.1 - 1.4e-06 28.4 0.0 2e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Toxin_7 PF05980.12 EPS26366.1 - 0.23 11.7 0.5 0.47 10.7 0.5 1.5 1 0 0 1 1 1 0 Toxin 7 MARVEL PF01284.23 EPS26367.1 - 2.3e-13 50.4 12.5 2.8e-13 50.1 12.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain Actin PF00022.19 EPS26368.1 - 8.8e-56 189.2 0.0 1.2e-28 99.8 0.0 2.4 2 1 0 2 2 2 2 Actin DASH_Dad4 PF08650.10 EPS26369.1 - 1.4e-32 111.5 8.0 1.5e-32 111.4 8.0 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 GM_CSF PF01109.17 EPS26369.1 - 0.015 15.5 0.4 0.016 15.4 0.4 1.1 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor CD34_antigen PF06365.12 EPS26369.1 - 0.026 14.1 0.5 0.027 14.1 0.5 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family DASH_Duo1 PF08651.10 EPS26369.1 - 0.042 13.6 2.0 0.06 13.1 1.9 1.4 1 1 0 1 1 1 0 DASH complex subunit Duo1 Biotin_carb_C PF02785.19 EPS26369.1 - 0.067 13.3 0.1 0.074 13.2 0.1 1.1 1 0 0 1 1 1 0 Biotin carboxylase C-terminal domain HOK_GEF PF01848.16 EPS26369.1 - 0.16 11.4 0.1 0.24 10.9 0.1 1.3 1 0 0 1 1 1 0 Hok/gef family YL1_C PF08265.11 EPS26370.1 - 1.7e-14 53.3 0.2 3.1e-14 52.4 0.2 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Got1 PF04178.12 EPS26372.1 - 5.2e-14 52.6 13.2 6.9e-14 52.2 13.2 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF373 PF04123.13 EPS26372.1 - 3.1 7.2 5.0 1 8.7 2.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF373) Profilin PF00235.19 EPS26373.1 - 3.7e-36 124.2 0.7 4.1e-36 124.1 0.7 1.0 1 0 0 1 1 1 1 Profilin ADP_ribosyl_GH PF03747.14 EPS26374.1 - 1e-59 202.7 0.6 1.2e-59 202.5 0.6 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Sec63 PF02889.16 EPS26377.1 - 3.6e-129 429.4 0.0 7.8e-80 267.7 0.1 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EPS26377.1 - 1.2e-52 178.2 0.4 1.1e-26 93.7 0.9 2.9 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 EPS26377.1 - 5.8e-23 81.8 0.0 5.2e-11 42.8 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EPS26377.1 - 1.3e-17 64.2 0.1 6.8e-07 29.6 0.0 4.6 4 2 0 4 4 4 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 EPS26377.1 - 1.9e-07 31.4 0.3 0.0072 16.6 0.0 3.8 2 2 0 2 2 2 2 AAA domain AAA_30 PF13604.6 EPS26377.1 - 3.6e-07 30.1 0.2 0.0052 16.5 0.4 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EPS26377.1 - 1.3e-05 25.6 0.7 0.0056 17.0 0.8 2.7 2 0 0 2 2 2 1 AAA domain Helicase_PWI PF18149.1 EPS26377.1 - 9.6e-05 22.5 0.3 0.00046 20.3 0.0 2.1 2 0 0 2 2 2 1 N-terminal helicase PWI domain IstB_IS21 PF01695.17 EPS26377.1 - 0.053 13.3 0.3 5.5 6.7 0.0 3.4 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_7 PF12775.7 EPS26377.1 - 0.072 12.6 0.0 14 5.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region PhoH PF02562.16 EPS26377.1 - 0.073 12.5 0.1 5.3 6.4 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein TniB PF05621.11 EPS26377.1 - 0.095 12.1 2.3 16 4.8 0.0 3.7 5 0 0 5 5 5 0 Bacterial TniB protein Synaptobrevin PF00957.21 EPS26378.1 - 1.9e-14 53.2 0.5 3.1e-14 52.5 0.5 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EPS26378.1 - 1.9e-12 47.0 0.0 3.8e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Metallophos PF00149.28 EPS26379.1 - 2.4e-18 67.4 0.0 5e-18 66.3 0.0 1.5 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 EPS26379.1 - 4.1e-12 46.8 0.1 1e-11 45.5 0.1 1.8 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 EPS26379.1 - 4.7e-12 46.3 2.4 1.2e-11 45.1 2.4 1.7 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 EPS26379.1 - 0.0062 17.0 0.1 0.026 15.1 0.1 2.0 2 0 0 2 2 2 1 PhoD-like phosphatase, N-terminal domain FAM76 PF16046.5 EPS26380.1 - 0.0085 15.5 0.4 0.0099 15.3 0.4 1.0 1 0 0 1 1 1 1 FAM76 protein Helo_like_N PF17111.5 EPS26380.1 - 0.015 14.7 0.8 0.026 13.9 0.1 1.7 2 1 0 2 2 2 0 Fungal N-terminal domain of STAND proteins ATG16 PF08614.11 EPS26380.1 - 0.026 14.7 0.4 0.026 14.7 0.4 1.5 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) 2OG-FeII_Oxy_2 PF13532.6 EPS26382.1 - 1.2e-27 97.3 0.0 2.7e-27 96.2 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3431 PF11913.8 EPS26384.1 - 3.2e-80 268.9 0.0 3.8e-80 268.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Ras PF00071.22 EPS26385.1 - 3.5e-39 134.0 0.0 1.4e-36 125.6 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EPS26385.1 - 8.8e-31 106.6 0.0 1.2e-30 106.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPS26385.1 - 1.1e-10 41.2 0.0 1.9e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EPS26385.1 - 9.6e-05 22.4 0.0 0.0002 21.4 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EPS26385.1 - 0.0021 18.4 0.0 0.006 17.0 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain Gtr1_RagA PF04670.12 EPS26385.1 - 0.0065 15.9 0.0 0.0085 15.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EPS26385.1 - 0.0073 15.8 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 EPS26385.1 - 0.01 16.1 0.1 0.024 14.9 0.0 1.6 2 1 0 2 2 1 0 AAA domain PduV-EutP PF10662.9 EPS26385.1 - 0.02 14.7 0.0 0.33 10.7 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.6 EPS26385.1 - 0.068 13.2 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EPS26385.1 - 0.086 13.1 0.2 0.23 11.7 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EPS26385.1 - 0.11 12.0 0.2 0.17 11.4 0.2 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 EPS26385.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.7 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 EPS26385.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sugar_tr PF00083.24 EPS26386.1 - 3.3e-106 355.9 26.9 3.8e-106 355.7 26.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS26386.1 - 1.6e-24 86.5 44.4 1.9e-14 53.4 15.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_A14 PF05767.12 EPS26386.1 - 0.61 10.3 5.5 0.68 10.1 0.0 3.3 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 ELO PF01151.18 EPS26386.1 - 0.66 9.4 9.6 0.58 9.6 0.2 3.2 3 0 0 3 3 3 0 GNS1/SUR4 family CoA_binding_3 PF13727.6 EPS26386.1 - 7 6.6 8.1 0.55 10.2 1.9 2.3 3 0 0 3 3 3 0 CoA-binding domain OATP PF03137.20 EPS26386.1 - 8.7 4.5 16.3 1.5 7.0 1.6 3.4 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family FMN_dh PF01070.18 EPS26388.1 - 4.9e-123 410.6 0.1 5.9e-123 410.3 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EPS26388.1 - 6e-23 80.8 0.1 1.2e-22 79.8 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EPS26388.1 - 4.3e-07 29.4 0.1 7.1e-07 28.7 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 EPS26388.1 - 3.3e-05 23.4 0.2 5.5e-05 22.7 0.2 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EPS26388.1 - 8.8e-05 21.7 0.3 0.00027 20.1 0.2 1.8 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 EPS26388.1 - 0.015 14.7 0.6 0.72 9.3 0.1 2.4 1 1 0 2 2 2 0 Histidine biosynthesis protein DUF561 PF04481.12 EPS26388.1 - 0.06 12.5 0.0 0.52 9.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF561) Cytotoxic PF09000.10 EPS26388.1 - 0.06 13.7 0.0 0.18 12.1 0.0 1.8 1 0 0 1 1 1 0 Cytotoxic ThiG PF05690.14 EPS26388.1 - 0.093 12.0 0.1 8.7 5.6 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Brr6_like_C_C PF10104.9 EPS26389.1 - 2.4e-35 121.2 0.7 3.1e-35 120.9 0.7 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain PBP1_TM PF14812.6 EPS26389.1 - 0.051 14.0 1.9 0.15 12.4 1.9 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Bud13 PF09736.9 EPS26390.1 - 7.8e-48 162.6 4.8 7.8e-48 162.6 4.8 2.5 3 1 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex ROF PF07073.12 EPS26390.1 - 0.2 11.8 0.4 0.44 10.7 0.4 1.5 1 0 0 1 1 1 0 Modulator of Rho-dependent transcription termination (ROF) DNA_binding_1 PF01035.20 EPS26391.1 - 3.8e-24 84.6 0.1 5e-24 84.2 0.1 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Pkinase PF00069.25 EPS26392.1 - 3.4e-41 141.4 0.4 1.9e-22 79.9 0.4 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EPS26392.1 - 2.8e-14 53.0 0.6 6.6e-10 38.7 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EPS26392.1 - 0.14 10.9 2.3 0.079 11.7 0.3 1.7 1 1 1 2 2 2 0 Fungal protein kinase Haspin_kinase PF12330.8 EPS26392.1 - 0.18 10.7 3.6 4.1 6.2 1.4 2.1 2 0 0 2 2 2 0 Haspin like kinase domain Phage_Gp23 PF10669.9 EPS26392.1 - 2.7 8.3 7.5 0.36 11.2 0.3 2.2 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) Metallophos PF00149.28 EPS26393.1 - 6.1e-10 39.9 0.0 3e-09 37.7 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EPS26393.1 - 1.4e-07 31.8 0.0 3.9e-05 23.9 0.0 2.5 3 0 0 3 3 3 2 Calcineurin-like phosphoesterase superfamily domain Ribonuclease PF00545.20 EPS26394.1 - 8.3e-11 42.5 0.1 1.1e-10 42.1 0.1 1.1 1 0 0 1 1 1 1 ribonuclease MF_alpha_N PF05436.11 EPS26394.1 - 0.11 12.4 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus ATP-synt_E PF05680.12 EPS26395.1 - 2 8.8 5.8 1.3 9.4 4.3 1.5 1 1 0 1 1 1 0 ATP synthase E chain Na_Ca_ex PF01699.24 EPS26396.1 - 4.6e-41 140.3 35.7 1.5e-20 73.6 11.3 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Anoctamin PF04547.12 EPS26397.1 - 2.6e-92 310.0 7.6 3.2e-92 309.7 7.6 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel STE2 PF02116.15 EPS26397.1 - 0.5 9.6 5.4 0.18 11.0 0.3 2.2 2 0 0 2 2 2 0 Fungal pheromone mating factor STE2 GPCR His_Phos_1 PF00300.22 EPS26399.1 - 0.0043 16.8 0.0 0.0065 16.2 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ThrE PF06738.12 EPS26400.1 - 9.2e-71 238.0 24.0 3.9e-66 222.9 3.5 3.1 2 1 1 3 3 3 2 Putative threonine/serine exporter ThrE_2 PF12821.7 EPS26400.1 - 7.1e-12 45.6 7.5 7.1e-12 45.6 7.5 2.8 2 1 1 3 3 3 1 Threonine/Serine exporter, ThrE DUF2985 PF11204.8 EPS26400.1 - 0.19 11.9 3.1 0.9 9.7 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2985) MFS_1 PF07690.16 EPS26401.1 - 2e-33 115.8 38.6 1.3e-28 100.0 25.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EPS26401.1 - 0.0045 15.9 8.2 0.0045 15.9 8.2 2.6 1 1 2 3 3 3 2 MFS_1 like family AMP-binding PF00501.28 EPS26402.1 - 6.3e-64 216.1 0.0 8.6e-64 215.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme RPN5_C PF18098.1 EPS26402.1 - 0.47 10.6 2.3 37 4.5 1.1 2.6 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN5 C-terminal domain Pectate_lyase_3 PF12708.7 EPS26403.1 - 1e-51 175.8 11.6 9e-42 143.3 4.5 2.7 2 1 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EPS26403.1 - 0.00035 20.2 8.6 0.0012 18.5 0.1 3.2 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase FAM53 PF15242.6 EPS26405.1 - 0.63 9.8 7.5 0.73 9.6 7.5 1.1 1 0 0 1 1 1 0 Family of FAM53 Macoilin PF09726.9 EPS26405.1 - 9.8 4.6 5.7 12 4.4 5.7 1.1 1 0 0 1 1 1 0 Macoilin family DUF3292 PF11696.8 EPS26406.1 - 2.6e-226 753.0 0.0 3.1e-226 752.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) PRT_C PF08372.10 EPS26406.1 - 0.06 13.1 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal MIP PF00230.20 EPS26407.1 - 1.8e-47 161.9 10.7 2.4e-47 161.6 10.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein NAD_binding_1 PF00175.21 EPS26409.1 - 7.7e-16 58.7 0.0 1.6e-15 57.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EPS26409.1 - 2.1e-06 27.9 0.0 1.7e-05 25.0 0.0 2.1 1 1 1 2 2 2 1 Ferric reductase NAD binding domain Globin PF00042.22 EPS26409.1 - 3.9e-06 27.4 0.0 1.2e-05 25.8 0.0 1.9 2 0 0 2 2 2 1 Globin FAD_binding_6 PF00970.24 EPS26409.1 - 1.9e-05 24.9 0.0 3.4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Protoglobin PF11563.8 EPS26409.1 - 0.03 14.2 0.0 0.072 13.0 0.0 1.6 1 0 0 1 1 1 0 Protoglobin TIG PF01833.24 EPS26410.1 - 0.077 13.1 0.2 0.12 12.4 0.2 1.5 1 1 0 1 1 1 0 IPT/TIG domain HLH PF00010.26 EPS26412.1 - 7.7e-09 35.4 0.1 1.8e-08 34.2 0.1 1.6 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Cytomega_UL20A PF05984.12 EPS26413.1 - 0.0022 18.3 0.2 0.0043 17.3 0.2 1.5 1 0 0 1 1 1 1 Cytomegalovirus UL20A protein Asparaginase_2 PF01112.18 EPS26413.1 - 1.4 7.8 6.4 1.6 7.6 6.4 1.1 1 0 0 1 1 1 0 Asparaginase AA_permease_2 PF13520.6 EPS26414.1 - 2.6e-55 188.0 53.1 3.3e-55 187.6 53.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPS26414.1 - 2e-22 79.5 41.2 2.6e-22 79.1 41.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3493 PF11998.8 EPS26414.1 - 0.13 12.4 0.2 0.49 10.6 0.2 2.1 1 0 0 1 1 1 0 Low psii accumulation1 / Rep27 DUF1182 PF06681.13 EPS26414.1 - 0.61 9.6 9.6 0.065 12.8 4.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1182) Pro-kuma_activ PF09286.11 EPS26417.1 - 2.8e-38 131.4 0.4 9.7e-38 129.7 0.1 2.1 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EPS26417.1 - 3.2e-10 39.8 0.1 6.1e-10 38.8 0.1 1.4 1 0 0 1 1 1 1 Subtilase family CBM_20 PF00686.19 EPS26418.1 - 1.5e-36 124.2 1.3 2.9e-36 123.3 0.2 2.0 2 0 0 2 2 2 1 Starch binding domain LPMO_10 PF03067.15 EPS26418.1 - 1.5e-07 32.3 2.6 1.5e-07 32.3 2.6 1.9 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Glyco_hydro_61 PF03443.14 EPS26418.1 - 0.017 15.0 0.4 0.034 14.1 0.0 1.7 2 0 0 2 2 2 0 Glycosyl hydrolase family 61 Serglycin PF04360.12 EPS26418.1 - 0.039 13.9 0.1 0.072 13.0 0.1 1.4 1 0 0 1 1 1 0 Serglycin TMEM154 PF15102.6 EPS26418.1 - 8.7 6.2 10.1 17 5.3 10.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family S36_mt PF10937.8 EPS26420.1 - 6.9 8.3 9.9 2.4 9.8 6.5 1.9 1 1 1 2 2 2 0 Ribosomal protein S36, mitochondrial YtxH PF12732.7 EPS26421.1 - 0.0018 18.8 34.3 18 6.0 5.4 5.8 2 1 0 2 2 1 0 YtxH-like protein Peptidase_C39_2 PF13529.6 EPS26421.1 - 0.028 15.0 0.7 0.62 10.6 0.0 2.8 3 0 0 3 3 3 0 Peptidase_C39 like family EAP30 PF04157.16 EPS26421.1 - 0.12 11.6 12.0 0.17 11.1 2.4 2.8 3 0 0 3 3 3 0 EAP30/Vps36 family XH PF03469.14 EPS26421.1 - 0.22 11.4 16.3 0.32 10.9 0.0 4.3 2 1 2 4 4 4 0 XH domain TFIIF_beta PF02270.15 EPS26421.1 - 0.31 11.2 4.2 8.3 6.6 0.1 3.1 3 0 0 3 3 3 0 TFIIF, beta subunit HTH domain DUF2802 PF10975.8 EPS26421.1 - 0.82 9.8 0.0 0.82 9.8 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2802) DUF883 PF05957.13 EPS26421.1 - 1.2 9.8 15.7 20 5.9 1.0 5.5 2 1 5 7 7 7 0 Bacterial protein of unknown function (DUF883) MccV PF17508.2 EPS26421.1 - 1.5 9.4 3.7 5.5 7.6 1.8 2.3 2 0 0 2 2 2 0 Microcin V bacteriocin Apolipoprotein PF01442.18 EPS26421.1 - 1.6 8.6 23.2 1.2 8.9 0.6 3.4 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain DUF4533 PF15047.6 EPS26421.1 - 2.4 7.6 10.5 0.67 9.5 1.9 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4533) CH_2 PF06294.11 EPS26421.1 - 3.9 7.7 5.3 15 5.8 0.5 3.4 3 0 0 3 3 3 0 CH-like domain in sperm protein DUF2115 PF09888.9 EPS26421.1 - 5.1 7.6 11.9 4.3 7.8 0.1 3.9 3 2 2 5 5 5 0 Uncharacterized protein conserved in archaea (DUF2115) CarD_CdnL_TRCF PF02559.16 EPS26421.1 - 6.7 7.5 14.6 6.2 7.6 2.7 4.5 3 1 1 4 4 4 0 CarD-like/TRCF domain TraG-D_C PF12696.7 EPS26422.1 - 0.085 12.8 1.2 0.13 12.2 1.2 1.2 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG T4SS-DNA_transf PF02534.14 EPS26422.1 - 0.13 11.1 1.7 0.17 10.7 1.7 1.1 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Sporozoite_P67 PF05642.11 EPS26422.1 - 3.8 5.5 10.8 4.9 5.1 10.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Con-6 PF10346.9 EPS26424.1 - 1.2e-26 92.4 9.1 4.9e-15 55.3 0.8 2.2 2 0 0 2 2 2 2 Conidiation protein 6 DUF3533 PF12051.8 EPS26425.1 - 1.5e-129 432.3 14.9 1.7e-129 432.1 14.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) HTH_Tnp_Tc5 PF03221.16 EPS26427.1 - 0.13 12.4 0.1 0.33 11.0 0.1 1.7 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain RAC_head PF16717.5 EPS26428.1 - 4.9e-30 104.4 7.3 4.9e-30 104.4 7.3 3.1 2 1 0 2 2 2 1 Ribosome-associated complex head domain DnaJ PF00226.31 EPS26428.1 - 1.2e-16 60.5 0.2 4.3e-16 58.8 0.2 2.0 1 0 0 1 1 1 1 DnaJ domain CemA PF03040.14 EPS26428.1 - 0.52 10.2 6.1 0.92 9.4 6.1 1.3 1 0 0 1 1 1 0 CemA family FUSC PF04632.12 EPS26428.1 - 0.93 7.9 5.2 1.6 7.1 5.2 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family TMPIT PF07851.13 EPS26428.1 - 3.1 6.9 6.0 5.6 6.1 6.0 1.4 1 0 0 1 1 1 0 TMPIT-like protein V_ATPase_I PF01496.19 EPS26428.1 - 5.7 4.7 14.9 0.086 10.7 7.3 1.6 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Complex1_LYR PF05347.15 EPS26429.1 - 0.00032 20.7 0.4 0.0007 19.6 0.2 1.7 2 0 0 2 2 2 1 Complex 1 protein (LYR family) RRM_1 PF00076.22 EPS26430.1 - 1.4e-08 34.4 0.0 2.8e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EPS26430.1 - 0.0029 17.6 0.0 0.0046 16.9 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EPS26430.1 - 0.23 11.3 0.0 0.39 10.6 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif Sterol_MT_C PF08498.10 EPS26431.1 - 3.9e-27 94.4 0.1 6.7e-27 93.6 0.1 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 EPS26431.1 - 5.4e-21 75.1 0.0 1e-20 74.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPS26431.1 - 3.1e-19 69.5 0.0 6.1e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPS26431.1 - 2e-16 60.1 0.0 3.1e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPS26431.1 - 1.8e-11 44.1 0.0 2.9e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPS26431.1 - 8.9e-10 38.3 0.0 3e-09 36.6 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EPS26431.1 - 1e-09 38.1 0.0 1.5e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 EPS26431.1 - 5.9e-09 36.6 0.0 1.2e-08 35.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 EPS26431.1 - 0.0016 17.1 0.0 0.0021 16.7 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_15 PF09445.10 EPS26431.1 - 0.0028 17.2 0.0 0.0044 16.6 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PCMT PF01135.19 EPS26431.1 - 0.0039 17.0 0.0 0.0066 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 EPS26431.1 - 0.0072 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PrmA PF06325.13 EPS26431.1 - 0.0073 15.7 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EPS26431.1 - 0.014 14.9 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain RrnaAD PF00398.20 EPS26431.1 - 0.017 14.2 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_2 PF00891.18 EPS26431.1 - 0.046 13.0 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_32 PF13679.6 EPS26431.1 - 0.054 13.5 0.1 0.11 12.5 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain TehB PF03848.14 EPS26431.1 - 0.096 12.1 0.1 0.24 10.8 0.0 1.7 2 0 0 2 2 2 0 Tellurite resistance protein TehB PALP PF00291.25 EPS26433.1 - 1.2e-41 143.0 2.8 1.4e-41 142.8 2.8 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme MFS_1 PF07690.16 EPS26434.1 - 1.4e-41 142.6 20.5 1.4e-41 142.6 20.5 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS26434.1 - 3.5e-15 55.8 1.9 3.5e-15 55.8 1.9 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EPS26434.1 - 5.8e-05 21.7 1.1 0.00011 20.8 1.1 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4536 PF15055.6 EPS26434.1 - 0.093 13.0 1.0 3.7 7.9 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4536) DUF2512 PF10710.9 EPS26434.1 - 0.096 12.3 2.9 0.28 10.8 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2512) GEMIN8 PF15348.6 EPS26434.1 - 3.3 7.9 5.6 5.8 7.1 5.6 1.3 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Phosphoesterase PF04185.14 EPS26435.1 - 1.8e-32 113.0 2.6 1.2e-31 110.3 2.6 1.9 1 1 0 1 1 1 1 Phosphoesterase family HIF-1a_CTAD PF08778.10 EPS26435.1 - 0.071 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 HIF-1 alpha C terminal transactivation domain Fungal_trans_2 PF11951.8 EPS26436.1 - 1.1e-42 146.3 0.3 1.6e-42 145.7 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS26436.1 - 2.7e-08 33.8 11.0 4.4e-08 33.1 11.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med3 PF11593.8 EPS26436.1 - 0.045 12.9 1.2 0.066 12.4 1.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Aldedh PF00171.22 EPS26437.1 - 2e-133 445.3 0.1 2.2e-133 445.2 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EPS26437.1 - 0.00026 20.2 0.0 0.0013 17.9 0.0 2.0 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 EPS26437.1 - 0.00055 19.5 0.1 0.0017 17.9 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) GATase PF00117.28 EPS26438.1 - 3.9e-15 56.1 0.0 5.7e-15 55.6 0.0 1.3 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EPS26438.1 - 0.0024 17.7 0.3 0.034 13.9 0.3 2.2 1 1 0 1 1 1 1 Peptidase C26 GATase_3 PF07685.14 EPS26438.1 - 0.094 12.3 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DJ-1_PfpI PF01965.24 EPS26438.1 - 0.17 11.7 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 DJ-1/PfpI family Isochorismatase PF00857.20 EPS26442.1 - 3.7e-20 72.8 0.0 3e-16 60.1 0.0 2.4 2 1 0 2 2 2 2 Isochorismatase family Acetyltransf_1 PF00583.25 EPS26443.1 - 1.3e-09 38.3 0.0 1.7e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EPS26443.1 - 4.3e-09 36.7 0.0 5.4e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EPS26443.1 - 2.7e-08 33.8 0.0 4.2e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EPS26443.1 - 0.00087 19.4 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPS26443.1 - 0.015 15.2 0.0 0.034 14.1 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein SnoaL_2 PF12680.7 EPS26444.1 - 0.0019 18.8 0.2 0.013 16.1 0.0 2.4 3 0 0 3 3 3 1 SnoaL-like domain SnoaL PF07366.12 EPS26444.1 - 0.026 14.3 0.0 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 SnoaL-like polyketide cyclase Paf1 PF03985.13 EPS26444.1 - 3.5 6.5 14.8 4.9 6.0 14.8 1.1 1 0 0 1 1 1 0 Paf1 RR_TM4-6 PF06459.12 EPS26444.1 - 8.5 6.1 12.2 13 5.5 12.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MFS_1 PF07690.16 EPS26446.1 - 2.1e-34 119.0 31.5 2.1e-34 119.0 31.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TMEM132D_C PF15706.5 EPS26446.1 - 4.4 7.2 8.2 7.3 6.4 0.4 2.8 3 0 0 3 3 3 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term GDC-P PF02347.16 EPS26447.1 - 1.6e-175 584.1 0.0 6.8e-164 545.8 0.0 2.5 3 0 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 EPS26447.1 - 0.00059 19.2 0.2 0.0013 18.1 0.2 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase RhgB_N PF09284.10 EPS26448.1 - 6e-110 366.7 3.5 8.9e-110 366.1 3.5 1.3 1 0 0 1 1 1 1 Rhamnogalacturonan lyase B, N-terminal CBM-like PF14683.6 EPS26448.1 - 1.6e-38 132.2 0.0 4.2e-38 130.8 0.0 1.8 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 EPS26448.1 - 2.7e-21 75.1 6.7 1.1e-20 73.2 6.7 2.2 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 EPS26448.1 - 0.00027 21.1 0.6 0.00027 21.1 0.6 3.1 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain DUF3823 PF12866.7 EPS26448.1 - 0.058 13.7 1.0 0.21 11.9 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3823) N-terminal domain Acylphosphatase PF00708.18 EPS26448.1 - 0.12 12.8 0.0 0.51 10.8 0.0 1.9 2 0 0 2 2 2 0 Acylphosphatase Peptidase_S28 PF05577.12 EPS26450.1 - 6.2e-56 190.0 1.8 2.4e-55 188.1 1.3 2.1 1 1 1 2 2 2 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 EPS26450.1 - 0.19 10.4 2.9 0.16 10.6 0.6 1.9 2 1 0 2 2 2 0 PS-10 peptidase S37 Sugar_tr PF00083.24 EPS26451.1 - 1.3e-123 413.2 21.3 1.7e-123 412.9 21.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS26451.1 - 1.4e-21 76.8 28.8 1.4e-21 76.8 28.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Mannitol_dh_C PF08125.13 EPS26452.1 - 5.1e-79 265.2 0.0 7.4e-79 264.7 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 EPS26452.1 - 1.4e-44 151.9 0.0 2.3e-44 151.2 0.0 1.4 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain adh_short PF00106.25 EPS26453.1 - 1.6e-36 125.6 0.0 3.5e-36 124.5 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS26453.1 - 2.9e-23 82.6 0.0 5.1e-23 81.9 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPS26453.1 - 1.8e-10 41.0 0.1 2.5e-10 40.5 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPS26453.1 - 9.4e-07 28.5 0.0 1.2e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EPS26453.1 - 1.2e-06 28.2 0.0 1.5e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EPS26453.1 - 5.6e-05 23.1 0.0 6.4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EPS26453.1 - 0.00012 21.3 0.1 0.0002 20.6 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 EPS26453.1 - 0.00029 21.1 0.1 0.0013 19.0 0.1 2.0 3 0 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain DUF1776 PF08643.10 EPS26453.1 - 0.033 13.6 0.0 0.044 13.2 0.0 1.4 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) NmrA PF05368.13 EPS26453.1 - 0.13 11.8 0.2 0.19 11.3 0.2 1.2 1 0 0 1 1 1 0 NmrA-like family 4HBT_3 PF13622.6 EPS26454.1 - 1.3e-58 199.2 3.0 1.5e-58 199.0 3.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.15 EPS26454.1 - 4.7e-19 68.5 0.0 6.4e-14 51.9 0.0 3.0 2 1 0 2 2 2 2 Acyl-CoA thioesterase GST_N_2 PF13409.6 EPS26455.1 - 2e-08 34.4 0.0 4e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EPS26455.1 - 2.7e-08 34.1 0.0 7.7e-08 32.6 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EPS26455.1 - 0.0028 17.6 0.0 0.0056 16.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EPS26455.1 - 0.015 15.5 0.0 0.028 14.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain tRNA-synt_1_2 PF13603.6 EPS26455.1 - 0.2 11.2 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 SLT PF01464.20 EPS26456.1 - 2e-11 43.6 0.4 5.2e-11 42.2 0.4 1.7 1 1 0 1 1 1 1 Transglycosylase SLT domain Glucosaminidase PF01832.20 EPS26456.1 - 0.0095 16.4 0.4 0.021 15.3 0.4 1.6 1 1 0 1 1 1 1 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase SLT_2 PF13406.6 EPS26456.1 - 0.084 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Transglycosylase SLT domain F-box-like PF12937.7 EPS26457.1 - 0.043 13.7 0.2 0.13 12.2 0.2 1.8 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 EPS26457.1 - 0.13 12.1 0.6 3 7.8 0.2 2.6 2 0 0 2 2 2 0 F-box domain p450 PF00067.22 EPS26458.1 - 4.7e-74 249.8 0.0 6.1e-74 249.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Kin17_mid PF10357.9 EPS26459.1 - 1.2e-52 177.1 2.4 1.2e-52 177.1 2.4 2.0 3 0 0 3 3 3 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.7 EPS26459.1 - 0.00021 21.5 1.6 0.00057 20.2 1.6 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EPS26459.1 - 0.00021 21.5 0.7 0.00066 19.9 0.7 1.9 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EPS26459.1 - 0.042 14.2 1.2 0.042 14.2 1.2 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) MHCassoc_trimer PF08831.10 EPS26459.1 - 0.087 12.9 0.6 0.54 10.3 0.1 2.4 2 0 0 2 2 2 0 Class II MHC-associated invariant chain trimerisation domain Actin PF00022.19 EPS26460.1 - 8.8e-21 74.0 0.0 1e-17 63.9 0.0 2.9 3 0 0 3 3 3 2 Actin Actin_micro PF17003.5 EPS26460.1 - 0.043 13.0 0.1 0.12 11.5 0.0 1.6 2 0 0 2 2 2 0 Putative actin-like family CBFD_NFYB_HMF PF00808.23 EPS26461.1 - 3.3e-18 65.7 0.4 5.5e-18 65.0 0.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EPS26461.1 - 2.6e-07 31.0 2.0 3.8e-07 30.5 0.0 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 EPS26461.1 - 0.015 15.3 0.0 0.023 14.7 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated YolD PF08863.10 EPS26461.1 - 0.13 12.3 6.7 0.12 12.4 5.4 1.6 2 0 0 2 2 2 0 YolD-like protein DUF3500 PF12006.8 EPS26461.1 - 0.17 11.4 0.7 1.2 8.5 0.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3500) adh_short PF00106.25 EPS26462.1 - 2.8e-46 157.5 0.1 3.2e-46 157.2 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS26462.1 - 4.3e-32 111.6 0.0 5.3e-32 111.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPS26462.1 - 7.7e-13 48.7 0.3 1.1e-12 48.3 0.3 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EPS26462.1 - 2.9e-06 27.3 0.2 3.7e-06 27.0 0.2 1.3 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EPS26462.1 - 6.7e-05 22.5 0.0 0.00045 19.8 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EPS26462.1 - 0.0033 17.0 0.5 0.0074 15.9 0.4 1.6 2 0 0 2 2 2 1 NmrA-like family Shikimate_DH PF01488.20 EPS26462.1 - 0.013 15.6 0.1 0.02 14.9 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 EPS26462.1 - 0.013 16.0 0.0 0.16 12.5 0.0 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF1776 PF08643.10 EPS26462.1 - 0.045 13.1 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 EPS26462.1 - 0.11 11.9 0.0 0.29 10.5 0.0 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Methyltransf_11 PF08241.12 EPS26462.1 - 0.11 13.1 0.0 0.27 11.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain zf-CCCH PF00642.24 EPS26463.1 - 3e-08 33.4 20.0 3e-07 30.2 2.5 3.1 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EPS26463.1 - 0.0058 16.7 3.3 0.0058 16.7 3.3 3.3 3 0 0 3 3 3 1 Zinc finger domain Torus PF16131.5 EPS26463.1 - 0.0069 17.1 2.3 0.47 11.2 0.3 2.5 2 0 0 2 2 2 1 Torus domain RRM_1 PF00076.22 EPS26463.1 - 0.009 15.8 0.0 0.014 15.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SCRG1 PF15224.6 EPS26463.1 - 0.12 12.5 3.7 0.13 12.4 0.1 2.4 2 0 0 2 2 2 0 Scrapie-responsive protein 1 zf-CCCH_3 PF15663.5 EPS26463.1 - 2.2 8.6 8.0 0.38 11.0 1.3 2.5 2 2 0 2 2 2 0 Zinc-finger containing family SMC_Nse1 PF07574.13 EPS26464.1 - 1.2e-66 224.3 0.2 1.7e-66 223.8 0.2 1.2 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 EPS26464.1 - 4e-13 49.4 9.2 4e-13 49.4 9.2 1.6 2 0 0 2 2 2 1 RING-like domain IL4 PF00727.18 EPS26464.1 - 0.0028 17.9 0.5 0.052 13.8 0.3 2.6 3 0 0 3 3 3 1 Interleukin 4 DUF4796 PF16044.5 EPS26464.1 - 0.012 15.2 0.2 0.029 13.9 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) zf-ANAPC11 PF12861.7 EPS26464.1 - 0.027 14.5 2.8 0.051 13.6 2.8 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 EPS26464.1 - 0.027 14.8 7.6 0.047 14.0 7.6 1.4 1 0 0 1 1 1 0 Ring finger domain FANCL_C PF11793.8 EPS26464.1 - 0.76 10.0 5.7 3.1 8.1 5.7 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4 PF00097.25 EPS26464.1 - 1.1 9.2 5.8 2.6 8.0 5.8 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H PF13771.6 EPS26464.1 - 1.5 9.1 6.9 4.2 7.7 5.3 2.2 1 1 1 2 2 2 0 PHD-like zinc-binding domain Glyco_hydro_65N PF03636.15 EPS26466.1 - 2.2e-32 112.6 0.1 3.8e-32 111.8 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65m PF03632.15 EPS26466.1 - 1.8e-26 92.9 1.8 3.5e-20 72.2 0.7 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65C PF03633.15 EPS26466.1 - 0.012 15.5 0.2 0.028 14.3 0.2 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, C-terminal domain Catalase PF00199.19 EPS26467.1 - 5.5e-166 552.4 0.0 6.9e-166 552.1 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase_C PF18011.1 EPS26467.1 - 9.2e-51 171.5 1.0 1.5e-50 170.8 1.0 1.4 1 0 0 1 1 1 1 C-terminal domain found in long catalases Catalase-rel PF06628.12 EPS26467.1 - 9.2e-17 61.0 0.7 1.1e-15 57.5 0.1 2.3 2 0 0 2 2 2 1 Catalase-related immune-responsive Acetyltransf_1 PF00583.25 EPS26468.1 - 2.1e-10 40.9 0.0 2.7e-10 40.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EPS26468.1 - 5e-09 36.2 0.0 7e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EPS26468.1 - 1.2e-08 35.3 0.0 1.7e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EPS26468.1 - 0.00026 21.1 0.3 0.011 15.8 0.1 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPS26468.1 - 0.006 16.5 0.0 0.018 15.0 0.0 1.8 1 1 0 1 1 1 1 FR47-like protein Epimerase PF01370.21 EPS26469.1 - 3e-15 56.3 0.1 1.1e-14 54.5 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EPS26469.1 - 2.5e-14 52.9 0.0 4.5e-14 52.1 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EPS26469.1 - 6.7e-12 45.7 0.1 8.3e-11 42.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EPS26469.1 - 5.2e-09 35.6 0.0 0.0014 17.8 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein GDP_Man_Dehyd PF16363.5 EPS26469.1 - 1.3e-08 34.6 0.0 2.2e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EPS26469.1 - 1.3e-07 31.4 0.1 2.7e-06 27.1 0.2 2.2 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 EPS26469.1 - 5.7e-06 25.7 0.1 8.1e-06 25.2 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 EPS26469.1 - 0.00033 20.2 0.0 0.00055 19.5 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPS26469.1 - 0.0034 17.3 0.3 0.021 14.8 0.3 2.0 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 EPS26469.1 - 0.13 11.4 0.1 0.2 10.7 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain NTP_transf_9 PF04248.12 EPS26470.1 - 4.7e-29 100.1 1.0 5.3e-29 100.0 1.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) Cupin_2 PF07883.11 EPS26472.1 - 1.4e-09 37.5 0.0 3.3e-09 36.3 0.0 1.7 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.12 EPS26472.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Esterase_phd PF10503.9 EPS26473.1 - 5.2e-11 42.5 4.9 2.9e-05 23.7 0.2 2.5 2 1 0 2 2 2 2 Esterase PHB depolymerase CBM_1 PF00734.18 EPS26473.1 - 5.6e-09 35.8 11.2 5.6e-09 35.8 11.2 3.3 3 0 0 3 3 3 1 Fungal cellulose binding domain Glyco_transf_20 PF00982.21 EPS26474.1 - 1e-145 486.1 0.0 1.1e-145 485.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.20 EPS26474.1 - 1.3e-07 31.3 0.0 1.9e-06 27.5 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EPS26474.1 - 1.7e-05 25.3 0.1 0.043 14.3 0.0 2.6 1 1 1 2 2 2 2 Glycosyl transferases group 1 DUF1931 PF09123.11 EPS26474.1 - 0.0061 16.7 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1931) Glyco_trans_1_2 PF13524.6 EPS26474.1 - 0.082 13.3 0.0 0.25 11.7 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferases group 1 GMC_oxred_N PF00732.19 EPS26476.1 - 2.7e-67 227.2 0.2 4.4e-67 226.5 0.0 1.4 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EPS26476.1 - 6.7e-33 114.2 0.0 1.1e-32 113.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EPS26476.1 - 1.8e-06 27.3 0.0 0.024 13.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 EPS26476.1 - 1.9e-05 23.6 0.4 0.002 16.9 0.2 2.1 2 0 0 2 2 2 2 HI0933-like protein Lycopene_cycl PF05834.12 EPS26476.1 - 3.7e-05 23.0 0.1 6.8e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EPS26476.1 - 5.7e-05 22.5 0.5 0.0067 15.7 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPS26476.1 - 9.5e-05 22.6 0.2 0.00024 21.3 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EPS26476.1 - 0.00026 20.3 0.1 0.00059 19.2 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 EPS26476.1 - 0.00028 20.3 0.1 0.5 9.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EPS26476.1 - 0.0003 20.5 0.3 0.0021 17.7 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EPS26476.1 - 0.0083 16.1 0.2 0.044 13.8 0.0 2.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 EPS26476.1 - 0.032 14.8 0.1 0.11 13.1 0.1 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EPS26476.1 - 0.078 13.2 0.1 0.21 11.8 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain Trp_halogenase PF04820.14 EPS26476.1 - 0.096 11.5 0.2 0.15 10.8 0.2 1.3 1 0 0 1 1 1 0 Tryptophan halogenase DUF3431 PF11913.8 EPS26480.1 - 5.8e-57 192.9 0.0 6.9e-57 192.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) p450 PF00067.22 EPS26481.1 - 1.2e-54 185.9 0.0 1.4e-54 185.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.18 EPS26482.1 - 7.2e-05 22.8 9.3 0.00015 21.8 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CoA_trans PF01144.23 EPS26483.1 - 2.7e-98 327.7 0.9 5.4e-60 202.5 0.0 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.6 EPS26483.1 - 0.0026 17.7 0.1 0.0056 16.6 0.1 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain DALR_2 PF09190.11 EPS26484.1 - 0.051 14.1 0.0 7.5 7.1 0.1 2.5 2 0 0 2 2 2 0 DALR domain Auxin_repressed PF05564.12 EPS26484.1 - 0.084 13.6 0.5 0.21 12.3 0.0 1.9 1 1 1 2 2 2 0 Dormancy/auxin associated protein MFS_1 PF07690.16 EPS26485.1 - 1.6e-35 122.7 23.8 1.6e-35 122.7 23.8 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2970 PF11174.8 EPS26485.1 - 0.074 12.9 1.3 1.7 8.6 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) MFS_1 PF07690.16 EPS26488.1 - 2.9e-36 125.1 41.9 7.3e-28 97.5 21.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EPS26488.1 - 6.2e-07 28.6 14.9 3.2e-06 26.3 2.3 2.1 1 1 1 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 EPS26488.1 - 0.045 12.6 14.9 0.13 11.1 14.9 1.9 1 1 0 1 1 1 0 Sugar (and other) transporter p450 PF00067.22 EPS26489.1 - 4.8e-71 239.9 0.0 5.7e-71 239.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_1 PF00175.21 EPS26490.1 - 8.2e-35 119.8 0.0 1.8e-34 118.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EPS26490.1 - 2.7e-31 107.8 0.0 7.6e-31 106.4 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.28 EPS26490.1 - 6.5e-22 77.5 0.1 1.1e-21 76.7 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 EPS26490.1 - 1.1e-06 28.9 0.0 0.00015 21.9 0.0 2.5 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 EPS26490.1 - 0.0086 16.3 0.0 0.76 10.0 0.0 2.6 1 1 1 2 2 2 1 Siderophore-interacting FAD-binding domain Collar PF07484.12 EPS26490.1 - 0.13 12.3 0.1 6.4 6.9 0.0 2.6 2 0 0 2 2 2 0 Phage Tail Collar Domain DUF3990 PF13151.6 EPS26491.1 - 0.17 11.5 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3990) p450 PF00067.22 EPS26492.1 - 2.5e-36 125.4 0.0 3.7e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 TRI5 PF06330.11 EPS26493.1 - 3.5e-29 101.8 0.2 4.4e-29 101.5 0.2 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Transp_Tc5_C PF04236.15 EPS26494.1 - 0.12 12.8 0.5 0.28 11.5 0.5 1.7 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain AMP-binding PF00501.28 EPS26495.1 - 4e-71 239.8 0.0 5.4e-71 239.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EPS26495.1 - 7.7e-32 110.6 0.0 9e-27 93.9 0.0 3.8 2 2 0 2 2 2 2 Condensation domain PP-binding PF00550.25 EPS26495.1 - 5.9e-07 29.8 0.0 1.4e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EPS26495.1 - 0.048 14.6 0.0 0.12 13.3 0.0 1.8 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain DUF2850 PF11012.8 EPS26495.1 - 0.2 12.0 0.8 0.4 11.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2850) p450 PF00067.22 EPS26496.1 - 5.4e-79 266.1 0.0 6.6e-79 265.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2207 PF09972.9 EPS26497.1 - 6.9 5.3 8.7 3.8 6.1 6.5 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Snf7 PF03357.21 EPS26498.1 - 0.0021 17.7 1.9 0.0026 17.4 1.9 1.1 1 0 0 1 1 1 1 Snf7 DUF4157 PF13699.6 EPS26498.1 - 0.26 11.5 4.8 0.23 11.7 2.1 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4157) bZIP_2 PF07716.15 EPS26499.1 - 1.3e-11 44.4 16.5 1.3e-11 44.4 16.5 2.7 2 1 1 3 3 3 2 Basic region leucine zipper bZIP_1 PF00170.21 EPS26499.1 - 7e-06 26.1 17.3 7e-06 26.1 17.3 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 EPS26499.1 - 0.00071 20.0 14.9 0.0016 18.9 14.9 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor APG6_N PF17675.1 EPS26499.1 - 0.17 12.4 13.3 0.32 11.5 13.3 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region CENP-H PF05837.12 EPS26499.1 - 2.1 8.8 11.7 4.9 7.6 11.7 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DivIC PF04977.15 EPS26499.1 - 9 6.1 9.0 0.52 10.1 2.3 2.1 1 1 1 2 2 2 0 Septum formation initiator Asp-B-Hydro_N PF05279.11 EPS26502.1 - 0.13 12.3 6.6 0.17 11.9 6.6 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Kdo PF06293.14 EPS26503.1 - 0.00065 19.1 0.2 0.0014 18.0 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EPS26503.1 - 0.011 15.3 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 EPS26503.1 - 0.028 14.3 1.0 0.028 14.3 1.0 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase PF00069.25 EPS26503.1 - 0.048 13.0 0.0 0.092 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain Bystin PF05291.11 EPS26504.1 - 4.8e-131 436.4 0.0 6.7e-131 435.9 0.0 1.2 1 0 0 1 1 1 1 Bystin Amidase PF01425.21 EPS26506.1 - 1.3e-118 396.9 0.2 1.5e-118 396.6 0.2 1.0 1 0 0 1 1 1 1 Amidase ADH_zinc_N PF00107.26 EPS26507.1 - 4.7e-16 58.9 0.0 9.2e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 EPS26507.1 - 0.0061 16.0 0.2 0.0088 15.5 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Ribosomal_L12 PF00542.19 EPS26507.1 - 0.12 12.7 0.6 0.24 11.8 0.6 1.5 1 0 0 1 1 1 0 Ribosomal protein L7/L12 C-terminal domain Metallophos PF00149.28 EPS26508.1 - 3.9e-11 43.8 2.3 3.9e-11 43.8 2.3 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 EPS26508.1 - 0.0013 19.0 0.0 0.0034 17.6 0.0 1.6 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Transket_pyr PF02779.24 EPS26509.1 - 2.3e-44 151.2 0.0 3.9e-44 150.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EPS26509.1 - 6.2e-35 119.8 0.1 2.7e-34 117.7 0.0 2.1 2 0 0 2 2 2 1 Transketolase, C-terminal domain GntR PF00392.21 EPS26509.1 - 0.19 11.4 0.4 4.7 6.9 0.1 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family zf-met PF12874.7 EPS26510.1 - 0.0055 17.0 0.3 0.012 16.0 0.3 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 EPS26510.1 - 0.0079 16.6 1.2 0.0079 16.6 1.2 1.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 EPS26510.1 - 0.019 15.2 1.4 0.032 14.5 1.4 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EPS26510.1 - 0.098 13.0 0.1 0.15 12.4 0.1 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-LYAR PF08790.11 EPS26510.1 - 0.099 12.6 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger zf-C2H2_4 PF13894.6 EPS26510.1 - 0.1 13.5 0.5 0.24 12.4 0.5 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger DUF1691 PF07950.11 EPS26511.1 - 4.3e-40 136.8 9.2 1.1e-33 116.1 4.9 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) TRM PF02005.16 EPS26512.1 - 9e-117 390.4 0.0 5.5e-100 335.2 0.0 2.1 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 EPS26512.1 - 1.6e-06 28.0 0.0 2.7e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.6 EPS26512.1 - 0.00023 21.0 0.0 0.00075 19.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPS26512.1 - 0.0021 18.7 0.0 0.0046 17.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF2067 PF09840.9 EPS26512.1 - 0.0065 16.1 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2067) PrmA PF06325.13 EPS26512.1 - 0.0085 15.5 0.4 0.02 14.3 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_3 PF01596.17 EPS26512.1 - 0.1 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase FAS_I_H PF18314.1 EPS26514.1 - 2.9e-80 268.7 0.0 7.3e-80 267.4 0.0 1.7 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain Fas_alpha_ACP PF18325.1 EPS26514.1 - 7.4e-77 257.2 0.0 1.5e-76 256.3 0.0 1.5 1 0 0 1 1 1 1 Fatty acid synthase subunit alpha Acyl carrier domain ketoacyl-synt PF00109.26 EPS26514.1 - 5.7e-22 78.5 0.0 1.2e-21 77.5 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 EPS26514.1 - 9e-17 61.3 0.0 2.1e-16 60.1 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 EPS26514.1 - 1.1e-11 44.7 0.0 2.8e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 EPS26514.1 - 2.1e-05 24.1 0.0 5.2e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPS26514.1 - 0.0026 17.7 0.0 0.0077 16.2 0.0 1.8 1 0 0 1 1 1 1 KR domain 4PPT_N PF17837.1 EPS26514.1 - 0.11 12.6 1.8 1.1 9.4 1.8 2.4 1 1 0 1 1 1 0 4'-phosphopantetheinyl transferase N-terminal domain DUF1729 PF08354.10 EPS26516.1 - 6.2e-160 531.9 0.0 9.6e-160 531.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 EPS26516.1 - 1.7e-91 307.1 0.0 2.6e-89 299.9 0.0 3.1 4 0 0 4 4 4 1 Acyl transferase domain FAS_meander PF17951.1 EPS26516.1 - 6.9e-53 178.4 0.0 1.7e-52 177.1 0.0 1.7 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain FAS_N PF17828.1 EPS26516.1 - 8.2e-43 145.5 0.1 3.4e-42 143.5 0.1 2.1 2 0 0 2 2 2 1 N-terminal domain in fatty acid synthase subunit beta SAT PF16073.5 EPS26516.1 - 1.3e-39 136.4 0.2 1e-38 133.5 0.0 2.5 4 0 0 4 4 4 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 EPS26516.1 - 3.5e-38 129.9 0.0 1e-37 128.5 0.0 1.8 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 EPS26516.1 - 5.1e-22 78.4 0.0 2e-21 76.5 0.0 2.1 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.15 EPS26516.1 - 0.3 10.4 1.2 2.8 7.2 1.2 2.3 1 1 0 1 1 1 0 Nitronate monooxygenase TFIIF_alpha PF05793.12 EPS26517.1 - 3.5e-10 39.1 57.6 1.4e-09 37.2 53.0 2.8 2 1 0 2 2 2 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Curto_V2 PF07325.11 EPS26517.1 - 2.4 8.0 9.6 0.039 13.8 1.2 2.1 2 0 0 2 2 2 0 Curtovirus V2 protein OPT PF03169.15 EPS26518.1 - 2.4e-203 677.2 33.2 2.7e-203 677.0 33.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF383 PF04063.14 EPS26519.1 - 2.1e-67 226.5 0.1 7.7e-67 224.7 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.13 EPS26519.1 - 2.4e-21 75.3 2.2 2.4e-21 75.3 2.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF384) Inositol_P PF00459.25 EPS26520.1 - 6.2e-66 222.7 0.0 6.9e-66 222.5 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DUF676 PF05057.14 EPS26521.1 - 8.1e-41 139.9 0.0 5e-26 91.6 0.0 3.2 3 0 0 3 3 3 3 Putative serine esterase (DUF676) DAGK_cat PF00781.24 EPS26522.1 - 1.5e-15 56.9 0.0 2.8e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain His_Phos_2 PF00328.22 EPS26523.1 - 8.7e-112 374.2 0.2 1.2e-111 373.8 0.2 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 EPS26523.1 - 9.5e-38 128.2 0.0 2e-37 127.2 0.0 1.6 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 EPS26523.1 - 7.9e-06 25.6 0.0 1.7e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Utp21 PF04192.12 EPS26524.1 - 7.8e-76 254.6 0.0 1.1e-75 254.1 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 EPS26524.1 - 4.6e-18 65.3 0.0 0.00046 20.4 0.1 5.7 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EPS26524.1 - 2.3e-11 44.0 32.9 5.3e-05 23.9 0.4 10.6 12 0 0 12 12 12 4 WD domain, G-beta repeat PALB2_WD40 PF16756.5 EPS26524.1 - 0.027 13.4 0.2 0.47 9.3 0.0 2.6 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Cytochrom_D1 PF02239.16 EPS26524.1 - 0.046 12.2 0.4 0.14 10.7 0.1 2.0 2 0 0 2 2 2 0 Cytochrome D1 heme domain Nup160 PF11715.8 EPS26524.1 - 0.15 10.7 0.2 1.6 7.2 0.0 2.5 3 0 0 3 3 3 0 Nucleoporin Nup120/160 XPG_I_2 PF12813.7 EPS26525.1 - 1.2e-69 234.5 0.0 1.7e-69 234.1 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.18 EPS26525.1 - 0.092 13.1 0.1 0.25 11.7 0.1 1.7 1 0 0 1 1 1 0 XPG I-region Serglycin PF04360.12 EPS26525.1 - 1.9 8.4 4.4 2.8 7.9 1.6 2.2 2 0 0 2 2 2 0 Serglycin Fcf1 PF04900.12 EPS26526.1 - 7.2e-37 125.8 0.3 7.2e-37 125.8 0.3 1.7 2 1 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 EPS26526.1 - 7.4e-12 45.6 0.7 1e-11 45.2 0.1 1.5 2 0 0 2 2 2 1 PIN like domain CDH PF02611.15 EPS26528.1 - 1.1e-05 25.2 0.0 1.6e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 CDP-diacylglycerol pyrophosphatase Pec_lyase_C PF00544.19 EPS26530.1 - 2e-15 57.0 12.9 4.9e-14 52.4 12.9 2.2 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 EPS26530.1 - 2.1e-05 24.4 14.4 5.3e-05 23.1 13.0 1.8 1 1 0 1 1 1 1 Right handed beta helix region Phage_attach PF05354.11 EPS26530.1 - 0.068 13.1 0.1 0.21 11.5 0.1 1.8 1 0 0 1 1 1 0 Phage Head-Tail Attachment Glyco_hydro_43 PF04616.14 EPS26531.1 - 2.4e-12 46.8 3.4 4e-12 46.1 3.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 UL21a PF17636.2 EPS26534.1 - 0.28 11.2 2.1 3.8 7.5 0.2 2.4 1 1 1 2 2 2 0 Viral Unique Long protein 21a HTH_Tnp_Tc5 PF03221.16 EPS26538.1 - 0.0017 18.4 0.1 0.0037 17.3 0.0 1.6 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain MiAMP1 PF09117.10 EPS26541.1 - 0.082 13.2 0.1 0.097 12.9 0.1 1.1 1 0 0 1 1 1 0 MiAMP1 MCRA PF06100.11 EPS26543.1 - 9.6e-176 585.4 0.0 1.1e-175 585.2 0.0 1.0 1 0 0 1 1 1 1 MCRA family NAD_binding_8 PF13450.6 EPS26543.1 - 4.7e-06 26.7 0.0 1.1e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EPS26543.1 - 0.007 16.4 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EPS26543.1 - 0.035 13.3 0.1 0.47 9.6 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EPS26543.1 - 0.055 13.0 0.0 0.11 12.0 0.0 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase PPDK_N PF01326.19 EPS26544.1 - 8e-113 377.0 0.0 1.1e-112 376.5 0.0 1.2 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers_C PF02896.18 EPS26544.1 - 2.6e-61 207.3 0.0 4.3e-61 206.6 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilizers PF00391.23 EPS26544.1 - 1.1e-24 85.9 0.8 5e-24 83.8 0.7 2.2 2 0 0 2 2 2 1 PEP-utilising enzyme, mobile domain Ldh_1_N PF00056.23 EPS26545.1 - 3.8e-29 101.6 0.0 6.1e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 EPS26545.1 - 2.9e-19 69.6 0.0 4.7e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain UDPG_MGDP_dh_N PF03721.14 EPS26545.1 - 0.03 13.9 0.0 0.06 12.9 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 EPS26545.1 - 0.11 12.7 0.8 0.31 11.3 0.2 2.0 2 0 0 2 2 2 0 TrkA-N domain F420_oxidored PF03807.17 EPS26545.1 - 0.15 12.7 2.7 2.2 8.9 2.0 3.0 3 1 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Glyco_trans_4_2 PF13477.6 EPS26545.1 - 0.2 11.7 0.0 0.37 10.8 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like EcKinase PF02958.20 EPS26546.1 - 1.4e-08 34.5 0.0 5.3e-08 32.5 0.0 1.8 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.23 EPS26546.1 - 3e-08 33.9 0.1 3e-08 33.9 0.1 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPS26546.1 - 0.024 14.2 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF3373 PF11853.8 EPS26546.1 - 0.11 11.6 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DUF1679 PF07914.11 EPS26546.1 - 0.21 10.4 0.0 0.4 9.5 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) YccV-like PF08755.11 EPS26547.1 - 3.2e-29 101.3 0.0 7.1e-29 100.2 0.0 1.6 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.6 EPS26547.1 - 2.6e-16 59.6 0.0 5.9e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.7 EPS26547.1 - 1.4e-11 44.1 1.1 3.2e-11 42.9 1.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EPS26547.1 - 7.4e-09 35.3 1.2 9.6e-09 34.9 0.1 1.8 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 EPS26547.1 - 0.016 15.1 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 F-box Elongin_A PF06881.11 EPS26547.1 - 0.021 15.3 0.0 0.037 14.6 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DnaJ PF00226.31 EPS26548.1 - 8.5e-25 86.7 0.3 8.5e-25 86.7 0.3 2.2 2 0 0 2 2 1 1 DnaJ domain zf-C2H2_jaz PF12171.8 EPS26548.1 - 3.1e-10 40.1 5.5 3.1e-10 40.1 5.5 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EPS26548.1 - 5.2e-08 33.0 3.3 5.2e-08 33.0 3.3 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EPS26548.1 - 9.3e-07 28.7 7.6 0.0035 17.3 0.4 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 EPS26548.1 - 1.6e-06 28.4 6.0 0.00019 21.7 1.4 2.5 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EPS26548.1 - 1.9e-06 28.2 8.5 0.015 16.1 1.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HE PF16278.5 EPS26548.1 - 1.2e-05 25.6 4.4 0.0021 18.5 0.3 3.5 4 0 0 4 4 3 2 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2 PF00096.26 EPS26548.1 - 0.00013 22.2 10.7 0.041 14.3 2.7 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type Transcrip_act PF04949.13 EPS26548.1 - 0.0079 16.1 0.1 0.0079 16.1 0.1 2.6 3 0 0 3 3 3 1 Transcriptional activator Actin_micro PF17003.5 EPS26548.1 - 0.025 13.7 1.7 0.57 9.3 0.0 2.2 2 0 0 2 2 2 0 Putative actin-like family zf-LYAR PF08790.11 EPS26548.1 - 0.071 13.0 4.4 1.7 8.6 0.5 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-FCS PF06467.14 EPS26548.1 - 0.1 12.6 2.6 1.1 9.2 0.2 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif C1_4 PF07975.12 EPS26548.1 - 0.1 12.8 0.6 2.7 8.3 0.0 2.5 2 0 0 2 2 2 0 TFIIH C1-like domain Cytochrome_C7 PF14522.6 EPS26548.1 - 0.19 11.7 2.9 1.6 8.8 0.3 2.7 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c LIM PF00412.22 EPS26548.1 - 0.3 11.4 2.8 3.7 7.8 0.3 2.4 2 0 0 2 2 2 0 LIM domain Cytochrom_c3_2 PF14537.6 EPS26548.1 - 0.78 10.2 5.5 2.8 8.5 0.3 2.7 2 0 0 2 2 2 0 Cytochrome c3 zf-H2C2_2 PF13465.6 EPS26548.1 - 1.2 9.7 3.8 2.1 8.9 0.1 2.7 3 0 0 3 3 2 0 Zinc-finger double domain R3H PF01424.22 EPS26549.1 - 2.7e-13 49.7 0.0 6.9e-13 48.4 0.0 1.7 1 0 0 1 1 1 1 R3H domain G-patch PF01585.23 EPS26549.1 - 2.2e-09 37.0 0.3 5e-09 35.9 0.3 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EPS26549.1 - 0.0002 21.4 0.2 0.0002 21.4 0.2 2.6 2 0 0 2 2 2 1 G-patch domain SAM_2 PF07647.17 EPS26549.1 - 0.33 11.1 1.4 0.72 10.0 0.0 2.3 3 0 0 3 3 3 0 SAM domain (Sterile alpha motif) Peptidase_C54 PF03416.19 EPS26551.1 - 2.7e-96 322.2 0.0 3.3e-96 322.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Histone PF00125.24 EPS26552.1 - 2.5e-22 79.7 0.5 3e-22 79.4 0.5 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EPS26552.1 - 0.00028 21.1 0.9 0.0004 20.6 0.0 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EPS26552.1 - 0.0005 20.5 0.0 0.00083 19.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.13 EPS26552.1 - 0.069 12.8 0.1 0.15 11.7 0.1 1.5 1 1 0 1 1 1 0 Replication protein C N-terminal domain Stm1_N PF09598.10 EPS26552.1 - 1.5 9.7 10.4 3.1 8.7 10.4 1.6 1 0 0 1 1 1 0 Stm1 Histone_H2A_C PF16211.5 EPS26553.1 - 4.8e-21 74.2 2.6 8.3e-21 73.4 2.6 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EPS26553.1 - 7.1e-17 62.0 0.0 9.4e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EPS26553.1 - 1e-05 25.7 0.0 1.4e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Complex1_LYR PF05347.15 EPS26554.1 - 7.4e-11 41.9 0.3 9.6e-11 41.6 0.3 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) 2-oxoacid_dh PF00198.23 EPS26555.1 - 1e-79 267.3 0.1 1.5e-79 266.7 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EPS26555.1 - 8e-19 67.3 2.0 1.6e-18 66.3 2.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EPS26555.1 - 0.00043 20.0 0.4 0.017 15.0 0.1 2.4 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 EPS26555.1 - 0.0014 19.3 0.2 0.32 11.7 0.1 2.5 1 1 1 2 2 2 1 HlyD family secretion protein RnfC_N PF13375.6 EPS26555.1 - 0.032 14.2 0.6 0.52 10.3 0.0 2.7 1 1 2 3 3 3 0 RnfC Barrel sandwich hybrid domain GCV_H PF01597.19 EPS26555.1 - 0.045 13.7 0.4 0.1 12.5 0.4 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein FAM76 PF16046.5 EPS26555.1 - 0.24 10.7 8.3 5 6.4 0.0 2.1 2 0 0 2 2 2 0 FAM76 protein Presenilin PF01080.17 EPS26555.1 - 0.8 8.4 7.5 1.1 7.9 7.5 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 EPS26555.1 - 0.84 8.3 7.2 1.3 7.7 7.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Apt1 PF10351.9 EPS26555.1 - 2.7 6.7 7.7 4.1 6.2 7.7 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Coilin_N PF15862.5 EPS26555.1 - 2.8 7.7 6.5 5.9 6.7 6.5 1.6 1 0 0 1 1 1 0 Coilin N-terminus Herpes_DNAp_acc PF04929.12 EPS26555.1 - 4.6 6.1 11.7 6.7 5.6 11.7 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF2052 PF09747.9 EPS26555.1 - 8.5 6.4 10.3 15 5.7 10.3 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) PCMT PF01135.19 EPS26557.1 - 1.8e-61 207.6 0.0 2.8e-60 203.7 0.0 2.0 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EPS26557.1 - 1.2e-09 38.2 0.0 1.8e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPS26557.1 - 6.9e-07 29.9 0.0 1.4e-06 28.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EPS26557.1 - 2.1e-06 27.8 0.0 3.4e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPS26557.1 - 1.3e-05 25.1 0.0 1.9e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS26557.1 - 0.00015 22.3 0.0 0.00028 21.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPS26557.1 - 0.00041 21.0 0.0 0.00076 20.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 EPS26557.1 - 0.01 15.5 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW FtsJ PF01728.19 EPS26557.1 - 0.017 15.3 0.0 0.027 14.6 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.14 EPS26557.1 - 0.028 14.0 0.0 0.056 13.0 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain DnaJ PF00226.31 EPS26558.1 - 1.5e-21 76.3 4.2 1.7e-21 76.1 1.0 2.6 2 0 0 2 2 2 1 DnaJ domain TPR_1 PF00515.28 EPS26558.1 - 1.9e-16 59.1 0.8 1.8e-05 24.3 0.0 8.1 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_2 PF07719.17 EPS26558.1 - 1.9e-16 58.8 10.1 0.0063 16.5 0.0 9.5 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 EPS26558.1 - 1.2e-12 47.8 6.3 0.0026 17.9 0.0 5.4 3 2 1 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 EPS26558.1 - 5.5e-11 42.8 7.3 7.6e-05 23.1 0.0 5.3 3 3 3 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 EPS26558.1 - 9.1e-11 41.7 15.6 0.084 13.7 0.0 7.9 3 3 5 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 EPS26558.1 - 6.7e-09 35.3 0.0 0.032 14.4 0.0 6.4 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 EPS26558.1 - 9e-08 32.3 7.9 0.52 11.1 0.0 7.8 8 1 0 8 8 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 EPS26558.1 - 3.7e-07 29.7 0.1 0.018 14.7 0.0 5.3 5 1 1 6 6 6 1 TPR repeat TPR_17 PF13431.6 EPS26558.1 - 1.2e-05 25.3 0.6 0.094 13.1 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 EPS26558.1 - 0.00011 22.7 18.7 0.0024 18.5 0.2 6.1 4 2 2 6 6 6 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EPS26558.1 - 0.0009 18.9 4.9 0.24 11.0 0.7 3.0 3 1 0 3 3 3 2 Bacterial type III secretion protein (HrpB1_HrpK) PknG_TPR PF16918.5 EPS26558.1 - 0.0012 17.6 0.6 0.043 12.5 0.0 2.9 3 0 0 3 3 3 1 Protein kinase G tetratricopeptide repeat ANAPC3 PF12895.7 EPS26558.1 - 0.0063 16.7 11.8 0.047 13.9 0.4 4.7 3 2 3 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EPS26558.1 - 0.0091 16.0 4.2 28 5.0 0.2 5.4 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.6 EPS26558.1 - 0.013 15.8 15.2 1.6 9.1 0.0 6.1 6 2 0 6 6 5 0 Tetratricopeptide repeat ELYS PF13934.6 EPS26558.1 - 0.073 13.0 1.8 0.15 12.0 0.3 2.2 2 1 0 2 2 2 0 Nuclear pore complex assembly KORA PF16509.5 EPS26558.1 - 0.18 12.1 0.3 1.1 9.5 0.1 2.4 2 0 0 2 2 2 0 TrfB plasmid transcriptional repressor ArnB_C PF18677.1 EPS26558.1 - 0.47 10.6 3.1 6.9 6.9 1.0 2.8 2 1 0 2 2 2 0 Archaellum regulatory network B, C-terminal domain SBF2 PF12335.8 EPS26558.1 - 0.89 9.1 4.2 1.2 8.7 0.1 2.7 3 0 0 3 3 3 0 Myotubularin protein PCRF PF03462.18 EPS26559.1 - 3.5e-50 170.6 0.6 2e-49 168.1 0.0 2.2 3 0 0 3 3 3 1 PCRF domain RF-1 PF00472.20 EPS26559.1 - 1.8e-34 118.1 1.3 4.5e-34 116.9 1.3 1.6 1 0 0 1 1 1 1 RF-1 domain MIR PF02815.19 EPS26559.1 - 0.069 13.0 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 MIR domain Mito_carr PF00153.27 EPS26560.1 - 6.9e-51 170.1 4.4 3e-21 75.1 0.1 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein DEAD PF00270.29 EPS26561.1 - 9.5e-43 146.0 0.0 1.4e-42 145.5 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPS26561.1 - 5.4e-28 97.6 0.7 7.8e-27 93.8 0.5 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPS26561.1 - 0.0044 17.0 0.0 0.009 16.0 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SMC_N PF02463.19 EPS26562.1 - 3.9e-20 72.2 18.3 5e-19 68.6 18.3 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EPS26562.1 - 6.2e-11 43.2 30.0 6.2e-11 43.2 30.0 5.1 2 2 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EPS26562.1 - 8.2e-10 39.0 2.6 7.5e-07 29.2 0.3 2.8 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EPS26562.1 - 2.5e-08 34.0 9.8 2.5e-08 34.0 9.8 3.7 2 2 0 2 2 2 1 AAA ATPase domain SMC_hinge PF06470.13 EPS26562.1 - 6.9e-07 29.6 0.1 4.3e-06 27.0 0.0 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_29 PF13555.6 EPS26562.1 - 0.00016 21.3 0.0 0.00035 20.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF745 PF05335.13 EPS26562.1 - 0.0026 17.5 13.8 0.0026 17.5 13.8 6.0 2 2 4 6 6 6 1 Protein of unknown function (DUF745) SbcCD_C PF13558.6 EPS26562.1 - 0.02 15.1 0.0 0.06 13.6 0.0 1.8 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.27 EPS26562.1 - 0.063 13.8 0.2 0.063 13.8 0.2 5.3 3 2 0 3 3 3 0 ABC transporter Peptidase_M20 PF01546.28 EPS26563.1 - 4.6e-33 114.7 0.0 5.9e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EPS26563.1 - 8e-11 41.8 0.0 1.5e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EPS26563.1 - 0.059 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 MRP-L20 PF12824.7 EPS26564.1 - 3.8e-64 215.8 5.4 4.4e-64 215.6 5.4 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 DUF4994 PF16385.5 EPS26564.1 - 0.0042 17.0 0.0 0.0066 16.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function Neugrin PF06413.11 EPS26564.1 - 0.032 14.2 0.2 0.06 13.3 0.2 1.5 1 0 0 1 1 1 0 Neugrin Hyccin PF09790.9 EPS26564.1 - 0.11 11.6 0.7 0.21 10.7 0.7 1.5 1 1 0 1 1 1 0 Hyccin HTH_32 PF13565.6 EPS26564.1 - 0.11 13.2 2.5 0.23 12.1 0.2 2.3 1 1 1 2 2 2 0 Homeodomain-like domain Cys_Met_Meta_PP PF01053.20 EPS26566.1 - 2.1e-35 122.0 0.0 2.9e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EPS26566.1 - 0.002 17.4 0.0 0.0036 16.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Nrap_D4 PF17405.2 EPS26567.1 - 4.5e-64 215.7 0.1 8.9e-64 214.7 0.1 1.5 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D5 PF17406.2 EPS26567.1 - 4.5e-58 195.6 0.1 1e-57 194.4 0.1 1.7 1 0 0 1 1 1 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D2 PF17403.2 EPS26567.1 - 9e-51 171.6 0.0 4e-48 163.0 0.0 2.5 2 0 0 2 2 2 2 Nrap protein PAP/OAS-like domain Nrap PF03813.14 EPS26567.1 - 8.9e-47 158.9 0.1 2.4e-46 157.5 0.1 1.8 2 0 0 2 2 2 1 Nrap protein domain 1 Nrap_D3 PF17404.2 EPS26567.1 - 2.1e-46 157.9 0.5 6.9e-46 156.2 0.1 2.1 2 0 0 2 2 2 1 Nrap protein domain 3 Nrap_D6 PF17407.2 EPS26567.1 - 1.2e-29 103.2 0.0 2.4e-29 102.3 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 6 HWE_HK PF07536.14 EPS26567.1 - 0.0061 17.2 0.3 0.046 14.4 0.0 2.6 3 0 0 3 3 3 1 HWE histidine kinase I-set PF07679.16 EPS26568.1 - 0.0031 17.6 0.2 0.45 10.6 0.0 4.2 4 0 0 4 4 4 1 Immunoglobulin I-set domain Peptidase_C12 PF01088.21 EPS26569.1 - 7.6e-63 212.1 0.0 1.1e-62 211.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Oxysterol_BP PF01237.18 EPS26570.1 - 2.3e-54 184.7 0.1 6.2e-52 176.7 0.1 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein U1snRNP70_N PF12220.8 EPS26570.1 - 0.23 12.1 6.6 3.7 8.2 2.6 2.7 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Taq-exonuc PF09281.10 EPS26570.1 - 0.29 11.1 0.9 6.2 6.8 0.0 2.4 2 0 0 2 2 2 0 Taq polymerase, exonuclease Cnd1_N PF12922.7 EPS26572.1 - 6.2e-61 205.1 0.3 1.6e-60 203.7 0.3 1.8 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.7 EPS26572.1 - 8.7e-48 162.4 4.7 9.1e-43 146.1 0.6 3.1 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EPS26572.1 - 5.9e-13 49.0 2.3 2.1e-05 24.8 0.0 4.6 3 1 0 3 3 3 2 HEAT repeats HEAT PF02985.22 EPS26572.1 - 4e-09 36.0 14.2 0.071 13.4 0.0 7.6 6 2 3 9 9 8 2 HEAT repeat Adaptin_N PF01602.20 EPS26572.1 - 6.7e-07 28.2 8.6 0.0061 15.2 0.6 4.8 4 1 0 4 4 4 2 Adaptin N terminal region HEAT_EZ PF13513.6 EPS26572.1 - 1.1e-06 29.1 7.0 0.45 11.1 0.0 5.9 5 0 0 5 5 5 3 HEAT-like repeat RTP1_C1 PF10363.9 EPS26572.1 - 1.9e-06 28.0 0.5 0.012 15.8 0.0 3.6 3 0 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 Cnd3 PF12719.7 EPS26572.1 - 0.00012 21.4 2.7 0.01 15.0 1.4 3.1 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain FlbD PF06289.11 EPS26572.1 - 0.052 13.1 0.1 0.13 11.8 0.1 1.6 1 0 0 1 1 1 0 Flagellar and Swarming motility proteins ptaRNA1_toxin PF12703.7 EPS26572.1 - 0.62 10.1 3.3 6.6 6.9 1.5 3.4 2 1 0 2 2 2 0 Toxin of toxin-antitoxin type 1 system Cohesin_HEAT PF12765.7 EPS26572.1 - 2.2 8.6 6.1 43 4.5 0.0 5.2 6 0 0 6 6 6 0 HEAT repeat associated with sister chromatid cohesion Pkinase PF00069.25 EPS26573.1 - 4.5e-43 147.5 0.0 1.5e-39 135.9 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EPS26573.1 - 3.8e-09 36.2 0.0 0.00012 21.4 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 EPS26573.1 - 0.0058 16.6 0.1 0.23 11.4 0.1 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family FTA2 PF13095.6 EPS26573.1 - 0.0083 15.8 0.1 1.1 8.9 0.0 3.0 2 1 1 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 EPS26573.1 - 0.099 11.9 0.0 13 5.0 0.0 2.2 2 0 0 2 2 2 0 Kinase-like CHIP_TPR_N PF18391.1 EPS26573.1 - 0.17 12.6 3.5 13 6.6 0.2 3.3 3 0 0 3 3 3 0 CHIP N-terminal tetratricopeptide repeat domain CENP-B_dimeris PF09026.10 EPS26573.1 - 2 8.9 9.2 44 4.6 1.8 3.4 3 0 0 3 3 3 0 Centromere protein B dimerisation domain OTU PF02338.19 EPS26574.1 - 7.2e-08 33.0 0.0 1.2e-07 32.2 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EPS26574.1 - 0.024 14.1 0.0 0.24 10.8 0.0 2.1 1 1 1 2 2 2 0 Peptidase C65 Otubain Bromodomain PF00439.25 EPS26575.1 - 9.5e-42 141.0 4.5 1.7e-20 72.8 0.3 2.7 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 EPS26575.1 - 1.1e-17 64.0 1.3 2.5e-17 62.9 1.3 1.6 1 0 0 1 1 1 1 BAH domain Stathmin PF00836.19 EPS26575.1 - 0.0015 18.5 3.9 0.0037 17.2 3.9 1.6 1 0 0 1 1 1 1 Stathmin family HHH_6 PF14579.6 EPS26575.1 - 0.13 12.5 0.2 30 5.0 0.1 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif CENP-B_dimeris PF09026.10 EPS26575.1 - 0.25 11.7 10.7 0.79 10.2 10.7 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain HTH_32 PF13565.6 EPS26575.1 - 0.88 10.2 6.9 11 6.7 0.1 3.9 3 0 0 3 3 3 0 Homeodomain-like domain DUF4611 PF15387.6 EPS26575.1 - 1.9 8.8 8.9 0.32 11.3 3.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) NOA36 PF06524.12 EPS26575.1 - 6.4 6.0 8.5 12 5.1 8.5 1.4 1 0 0 1 1 1 0 NOA36 protein zf-CCCH PF00642.24 EPS26576.1 - 2.2e-11 43.4 10.6 2.4e-06 27.3 1.9 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EPS26576.1 - 3.5e-10 39.5 9.5 2.2e-06 27.3 2.4 2.5 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EPS26576.1 - 6e-09 35.7 16.5 4.1e-05 23.5 1.8 2.4 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 EPS26576.1 - 5.1e-08 33.6 5.7 0.0014 19.3 0.4 2.4 1 1 1 2 2 2 2 Torus domain zf-CCCH_3 PF15663.5 EPS26576.1 - 0.00051 20.2 1.3 0.00092 19.4 1.3 1.3 1 0 0 1 1 1 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 EPS26576.1 - 0.0071 16.8 14.1 0.18 12.4 3.2 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger TBPIP PF07106.13 EPS26577.1 - 3.1e-18 65.5 0.1 4.7e-18 64.9 0.1 1.3 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain Penicillinase_R PF03965.16 EPS26577.1 - 0.00077 19.8 0.2 0.0018 18.6 0.1 1.6 1 1 0 1 1 1 1 Penicillinase repressor DUF4349 PF14257.6 EPS26577.1 - 0.0018 17.7 8.0 0.0026 17.3 8.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) Macoilin PF09726.9 EPS26577.1 - 0.0055 15.3 3.6 0.0059 15.2 3.6 1.0 1 0 0 1 1 1 1 Macoilin family HOOK PF05622.12 EPS26577.1 - 0.0056 14.9 2.9 0.0089 14.2 2.8 1.6 2 0 0 2 2 2 1 HOOK protein DUF4423 PF14394.6 EPS26577.1 - 0.0062 16.3 1.9 0.01 15.5 1.9 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4423) FtsX_ECD PF18075.1 EPS26577.1 - 0.01 16.5 0.2 0.021 15.4 0.2 1.6 1 0 0 1 1 1 1 FtsX extracellular domain Takusan PF04822.13 EPS26577.1 - 0.013 15.4 0.3 0.013 15.4 0.3 1.8 2 0 0 2 2 2 0 Takusan TFIIE_beta PF02186.15 EPS26577.1 - 0.038 14.3 0.4 1.6 9.1 0.1 2.4 2 0 0 2 2 2 0 TFIIE beta subunit core domain DMPK_coil PF08826.10 EPS26577.1 - 0.057 13.5 5.9 0.14 12.3 5.9 1.7 1 0 0 1 1 1 0 DMPK coiled coil domain like CCDC92 PF14916.6 EPS26577.1 - 0.11 12.3 0.9 67 3.4 0.1 3.3 3 0 0 3 3 3 0 Coiled-coil domain of unknown function DUF4407 PF14362.6 EPS26577.1 - 0.23 10.8 8.1 0.63 9.3 7.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) YabA PF06156.13 EPS26577.1 - 0.44 11.2 2.0 0.75 10.5 0.4 2.1 1 1 1 2 2 2 0 Initiation control protein YabA TMF_TATA_bd PF12325.8 EPS26577.1 - 0.46 10.7 7.0 0.89 9.8 3.8 2.6 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4140 PF13600.6 EPS26577.1 - 0.52 10.8 9.4 0.81 10.2 2.3 2.7 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) CENP-H PF05837.12 EPS26577.1 - 0.73 10.3 8.7 3.7 8.0 2.3 2.7 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DivIC PF04977.15 EPS26577.1 - 0.94 9.3 10.3 0.32 10.8 1.1 2.7 2 1 1 3 3 3 0 Septum formation initiator APG6_N PF17675.1 EPS26577.1 - 1.2 9.6 10.0 3 8.4 9.4 1.9 1 1 1 2 2 2 0 Apg6 coiled-coil region ZapB PF06005.12 EPS26577.1 - 2.3 8.7 10.8 1.5 9.3 1.3 3.0 1 1 1 2 2 2 0 Cell division protein ZapB Sel1 PF08238.12 EPS26578.1 - 9.9e-16 57.8 25.1 6.7e-07 29.8 0.0 7.0 8 0 0 8 8 8 4 Sel1 repeat TPR_1 PF00515.28 EPS26578.1 - 0.00082 19.1 0.1 0.0057 16.4 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EPS26578.1 - 0.16 12.2 0.0 0.16 12.2 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EPS26578.1 - 0.42 11.6 0.0 0.42 11.6 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 EPS26578.1 - 3.7 7.9 7.9 0.53 10.6 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Helicase_C_2 PF13307.6 EPS26579.1 - 3.8e-57 193.2 0.0 1.6e-56 191.2 0.0 2.1 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.15 EPS26579.1 - 2.8e-49 167.1 0.0 6e-49 166.0 0.0 1.6 1 0 0 1 1 1 1 DEAD_2 HBB PF06777.11 EPS26579.1 - 0.022 14.4 0.1 0.06 13.0 0.0 1.8 2 0 0 2 2 2 0 Helical and beta-bridge domain Ribosomal_L27A PF00828.19 EPS26580.1 - 1.2e-22 80.9 0.0 1.8e-22 80.4 0.0 1.2 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Hydrolase_4 PF12146.8 EPS26581.1 - 0.075 12.3 0.0 0.24 10.7 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 PLDc PF00614.22 EPS26582.1 - 5.6e-14 51.6 0.1 3.4e-06 27.0 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 EPS26582.1 - 3.1e-13 49.7 0.0 9.9e-07 28.7 0.0 2.8 2 1 0 2 2 2 2 PLD-like domain PX PF00787.24 EPS26582.1 - 2.4e-07 30.7 0.0 2.3e-06 27.6 0.0 2.6 2 1 0 2 2 2 1 PX domain PAP_assoc PF03828.19 EPS26583.1 - 0.00014 22.0 0.0 0.0075 16.5 0.0 2.5 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EPS26583.1 - 0.0076 16.5 0.0 0.014 15.7 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain Glyco_transf_20 PF00982.21 EPS26584.1 - 3e-147 491.1 0.0 7e-147 489.9 0.0 1.5 2 0 0 2 2 2 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EPS26584.1 - 3.4e-83 278.4 0.0 5.5e-83 277.7 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase MFS_1 PF07690.16 EPS26585.1 - 2.3e-18 66.3 54.5 9e-18 64.3 50.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PP28 PF10252.9 EPS26586.1 - 4.2e-30 104.0 11.6 4.2e-30 104.0 11.6 2.8 3 0 0 3 3 3 2 Casein kinase substrate phosphoprotein PP28 CENP-B_dimeris PF09026.10 EPS26586.1 - 1.8 9.0 10.9 0.97 9.9 4.3 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain UNC-50 PF05216.13 EPS26587.1 - 7.3e-86 287.3 8.3 8.7e-86 287.0 8.3 1.0 1 0 0 1 1 1 1 UNC-50 family YobH PF13996.6 EPS26587.1 - 0.18 11.9 1.6 0.52 10.4 1.6 1.8 1 0 0 1 1 1 0 YobH-like protein Sec7 PF01369.20 EPS26588.1 - 9.2e-28 97.2 0.0 2e-27 96.1 0.0 1.5 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 EPS26588.1 - 2.3e-19 69.9 0.3 1.3e-18 67.5 0.0 2.4 3 0 0 3 3 3 1 Pleckstrin homology domain Tektin PF03148.14 EPS26588.1 - 0.064 12.0 0.1 0.11 11.3 0.1 1.2 1 0 0 1 1 1 0 Tektin family Flavodoxin_1 PF00258.25 EPS26588.1 - 0.069 13.3 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin SpoIIP PF07454.11 EPS26589.1 - 0.011 15.3 15.4 0.011 15.2 15.4 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF1168 PF06658.12 EPS26589.1 - 0.012 15.5 30.7 0.014 15.2 30.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Eapp_C PF10238.9 EPS26589.1 - 0.014 15.5 13.4 0.016 15.3 13.4 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein Vfa1 PF08432.10 EPS26589.1 - 0.019 15.3 28.7 0.02 15.2 28.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PcfK PF14058.6 EPS26589.1 - 0.022 15.1 27.9 0.027 14.7 27.9 1.1 1 0 0 1 1 1 0 PcfK-like protein RPN2_C PF18004.1 EPS26589.1 - 0.023 14.6 27.2 0.025 14.5 27.2 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF3807 PF12720.7 EPS26589.1 - 0.029 14.7 21.1 0.032 14.5 21.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Connexin PF00029.19 EPS26589.1 - 0.047 13.4 16.3 0.052 13.3 16.3 1.1 1 0 0 1 1 1 0 Connexin RNA_pol_Rpc4 PF05132.14 EPS26589.1 - 0.052 14.0 15.9 0.058 13.8 15.9 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF1764 PF08576.10 EPS26589.1 - 0.062 14.2 25.0 0.076 13.9 25.0 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) PPL5 PF18168.1 EPS26589.1 - 0.068 12.5 12.7 0.061 12.6 12.7 1.1 1 0 0 1 1 1 0 Prim-pol family 5 PRC2_HTH_1 PF18118.1 EPS26589.1 - 0.088 13.6 15.4 0.1 13.4 15.4 1.2 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain NARP1 PF12569.8 EPS26589.1 - 0.1 11.5 27.3 0.1 11.5 27.3 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 CPSF100_C PF13299.6 EPS26589.1 - 0.12 12.6 13.1 0.13 12.5 13.1 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Afi1 PF07792.12 EPS26589.1 - 0.12 12.9 11.5 0.14 12.7 11.5 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking BSMAP PF12280.8 EPS26589.1 - 0.21 11.8 10.9 0.27 11.4 10.9 1.1 1 0 0 1 1 1 0 Brain specific membrane anchored protein DUF5427 PF10310.9 EPS26589.1 - 0.22 10.4 16.8 0.23 10.4 16.8 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) FAM176 PF14851.6 EPS26589.1 - 0.28 10.8 8.8 0.35 10.5 8.8 1.1 1 0 0 1 1 1 0 FAM176 family ORC_WH_C PF18137.1 EPS26589.1 - 0.3 11.1 16.2 0.38 10.8 16.2 1.1 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal DUF2828 PF11443.8 EPS26589.1 - 0.34 9.0 19.0 0.36 8.8 19.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Presenilin PF01080.17 EPS26589.1 - 0.35 9.6 13.5 0.35 9.6 13.5 1.0 1 0 0 1 1 1 0 Presenilin AIF_C PF14721.6 EPS26589.1 - 0.35 11.2 12.1 0.41 11.0 12.1 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term TraV PF09676.10 EPS26589.1 - 0.37 11.8 14.4 0.38 11.7 14.4 1.1 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) EIIBC-GUT_N PF03612.14 EPS26589.1 - 0.4 10.4 14.1 0.47 10.2 14.1 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus GEN1_C PF18380.1 EPS26589.1 - 0.42 11.5 11.0 0.62 11.0 11.0 1.3 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain RR_TM4-6 PF06459.12 EPS26589.1 - 0.43 10.4 21.5 0.46 10.3 21.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3464 PF11947.8 EPS26589.1 - 0.44 10.3 22.5 0.6 9.9 22.5 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 CobT PF06213.12 EPS26589.1 - 0.49 9.8 7.6 0.48 9.8 7.6 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Tim54 PF11711.8 EPS26589.1 - 0.56 8.9 19.3 0.62 8.8 19.3 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DDHD PF02862.17 EPS26589.1 - 0.58 10.3 11.7 0.67 10.1 11.7 1.2 1 0 0 1 1 1 0 DDHD domain Cas_Csy4 PF09618.10 EPS26589.1 - 0.6 10.2 12.4 0.68 10.1 12.4 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) DAG_kinase_N PF14513.6 EPS26589.1 - 0.76 10.0 15.0 0.84 9.8 15.0 1.1 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus GAGA_bind PF06217.12 EPS26589.1 - 0.83 9.9 24.2 0.91 9.8 24.2 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Paramyxo_ncap PF00973.19 EPS26589.1 - 0.95 8.3 11.8 0.97 8.3 11.8 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein LicD PF04991.13 EPS26589.1 - 0.95 9.6 18.1 1 9.4 18.1 1.1 1 0 0 1 1 1 0 LicD family DUF4228 PF14009.6 EPS26589.1 - 1.1 9.6 11.5 1.2 9.5 11.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) AAA_11 PF13086.6 EPS26589.1 - 1.1 9.0 16.3 1.1 8.9 16.3 1.0 1 0 0 1 1 1 0 AAA domain GNAT_acetyltr_2 PF13718.6 EPS26589.1 - 1.1 8.5 10.5 1.3 8.4 10.5 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 MAP17 PF15807.5 EPS26589.1 - 1.3 9.2 16.2 1.8 8.8 16.2 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Rrn6 PF10214.9 EPS26589.1 - 1.3 7.4 15.0 1.7 7.1 15.0 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor SpoVR PF04293.13 EPS26589.1 - 1.5 7.5 12.3 1.6 7.3 12.3 1.0 1 0 0 1 1 1 0 SpoVR like protein FancD2 PF14631.6 EPS26589.1 - 1.6 6.0 16.6 1.7 5.9 16.6 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Sec62 PF03839.16 EPS26589.1 - 1.7 8.1 24.1 2.3 7.7 24.1 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 MDM31_MDM32 PF08118.11 EPS26589.1 - 1.8 7.2 11.4 1.9 7.1 11.4 1.0 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins DUF5308 PF17233.2 EPS26589.1 - 1.8 8.7 7.3 2.1 8.5 7.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5308) Ctr PF04145.15 EPS26589.1 - 1.8 9.1 7.8 2.1 9.0 7.8 1.1 1 0 0 1 1 1 0 Ctr copper transporter family GCD14 PF08704.10 EPS26589.1 - 1.9 8.1 9.8 1.9 8.1 9.8 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Zip PF02535.22 EPS26589.1 - 2 7.5 10.1 2.1 7.5 10.1 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter EOS1 PF12326.8 EPS26589.1 - 2.2 8.2 11.4 2.3 8.1 11.4 1.2 1 0 0 1 1 1 0 N-glycosylation protein RPOL_N PF14700.6 EPS26589.1 - 2.2 7.6 23.8 2.6 7.4 23.8 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal RPA43_OB PF17875.1 EPS26589.1 - 2.3 8.9 11.9 2.9 8.5 11.9 1.2 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I DUF4569 PF15133.6 EPS26589.1 - 2.4 7.8 14.8 2.4 7.8 14.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Hydin_ADK PF17213.3 EPS26589.1 - 2.7 8.2 12.1 3.3 8.0 12.1 1.1 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain MCM_bind PF09739.9 EPS26589.1 - 2.8 6.3 17.6 3 6.2 17.6 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Membralin PF09746.9 EPS26589.1 - 3.4 6.6 11.2 3.8 6.5 11.2 1.0 1 0 0 1 1 1 0 Tumour-associated protein API5 PF05918.11 EPS26589.1 - 3.7 6.2 23.2 4.1 6.1 23.2 1.0 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) CDC45 PF02724.14 EPS26589.1 - 3.8 5.7 19.3 4 5.6 19.3 1.0 1 0 0 1 1 1 0 CDC45-like protein YL1 PF05764.13 EPS26589.1 - 4 7.5 36.1 4.6 7.3 36.1 1.0 1 0 0 1 1 1 0 YL1 nuclear protein Peroxin-13_N PF04088.13 EPS26589.1 - 4.1 7.7 13.0 5.1 7.4 13.0 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region FAM91_C PF14648.6 EPS26589.1 - 4.1 6.1 11.9 5 5.8 11.9 1.0 1 0 0 1 1 1 0 FAM91 C-terminus EMC3_TMCO1 PF01956.16 EPS26589.1 - 4.3 7.0 19.1 4.6 6.9 19.1 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Serinc PF03348.15 EPS26589.1 - 4.6 6.1 9.2 4.8 6.0 9.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) AAA_23 PF13476.6 EPS26589.1 - 4.6 7.7 24.0 5.5 7.4 24.0 1.1 1 0 0 1 1 1 0 AAA domain Neur_chan_memb PF02932.16 EPS26589.1 - 4.7 7.2 12.3 4.9 7.1 12.3 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region YqfQ PF14181.6 EPS26589.1 - 5 7.3 22.5 6 7.0 22.5 1.1 1 0 0 1 1 1 0 YqfQ-like protein DUF913 PF06025.12 EPS26589.1 - 5.2 5.9 10.6 5.5 5.9 10.6 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DDRGK PF09756.9 EPS26589.1 - 5.8 6.5 31.2 6.5 6.3 31.2 1.1 1 0 0 1 1 1 0 DDRGK domain MDFI PF15316.6 EPS26589.1 - 6.2 6.9 12.7 6.9 6.7 12.7 1.2 1 0 0 1 1 1 0 MyoD family inhibitor SR-25 PF10500.9 EPS26589.1 - 6.5 6.3 53.4 11 5.6 53.4 1.4 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4770 PF15994.5 EPS26589.1 - 6.5 6.9 22.3 8.3 6.6 22.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) Sre PF03125.18 EPS26589.1 - 6.6 5.8 11.1 7.4 5.6 11.1 1.0 1 0 0 1 1 1 0 C. elegans Sre G protein-coupled chemoreceptor Folate_carrier PF01770.18 EPS26589.1 - 6.8 5.3 14.5 7.8 5.1 14.5 1.0 1 0 0 1 1 1 0 Reduced folate carrier ALMT PF11744.8 EPS26589.1 - 6.9 5.4 15.8 7.8 5.2 15.8 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Band_3_cyto PF07565.13 EPS26589.1 - 7.5 6.3 13.0 7.8 6.2 13.0 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain PIEZO PF15917.5 EPS26589.1 - 9.2 5.7 23.7 11 5.5 23.7 1.0 1 0 0 1 1 1 0 Piezo Cnn_1N PF07989.11 EPS26590.1 - 1.5e-23 82.7 11.3 1.5e-23 82.7 11.3 13.3 9 2 5 14 14 14 4 Centrosomin N-terminal motif 1 Mto2_bdg PF12808.7 EPS26590.1 - 4e-20 71.9 26.3 8.9e-17 61.1 16.8 12.7 12 4 2 14 14 14 2 Micro-tubular organiser Mto1 C-term Mto2-binding region QRPTase_C PF01729.19 EPS26591.1 - 1.2e-47 161.9 0.2 3.9e-47 160.2 0.2 1.7 1 1 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 EPS26591.1 - 8.5e-20 70.6 0.1 2.8e-19 68.9 0.0 2.0 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain Ribul_P_3_epim PF00834.19 EPS26591.1 - 0.044 13.2 0.0 0.19 11.1 0.0 1.8 1 1 1 2 2 2 0 Ribulose-phosphate 3 epimerase family Pectinesterase PF01095.19 EPS26592.1 - 8.1e-47 159.4 8.4 1e-46 159.0 8.4 1.1 1 0 0 1 1 1 1 Pectinesterase ChitinaseA_N PF08329.10 EPS26592.1 - 0.073 12.7 0.3 0.33 10.6 0.1 2.1 2 0 0 2 2 2 0 Chitinase A, N-terminal domain LETM1 PF07766.13 EPS26593.1 - 5.5e-08 32.5 1.9 8.3e-06 25.3 1.9 2.4 1 1 0 1 1 1 1 LETM1-like protein PAS_9 PF13426.7 EPS26594.1 - 3.8e-28 97.8 0.0 1e-17 64.3 0.0 3.5 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.12 EPS26594.1 - 1.5e-20 73.3 0.0 7.7e-12 45.3 0.0 3.7 3 0 0 3 3 3 3 PAS fold GATA PF00320.27 EPS26594.1 - 1.3e-13 50.3 7.0 2.6e-13 49.3 7.0 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.25 EPS26594.1 - 1.9e-13 50.4 0.0 0.0012 18.8 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS_4 PF08448.10 EPS26594.1 - 1.3e-08 35.0 0.0 0.07 13.4 0.0 3.9 4 0 0 4 4 4 3 PAS fold PAS_11 PF14598.6 EPS26594.1 - 6.1e-06 26.3 0.0 0.059 13.5 0.0 3.0 4 0 0 4 4 4 2 PAS domain PAS_8 PF13188.7 EPS26594.1 - 0.0019 18.2 0.0 0.048 13.7 0.0 2.8 3 0 0 3 3 3 1 PAS domain Ras PF00071.22 EPS26595.1 - 3.1e-09 36.6 0.0 4.7e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Zn_clus PF00172.18 EPS26599.1 - 1e-08 35.1 13.2 1.7e-08 34.5 13.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NUDE_C PF04880.13 EPS26599.1 - 5.5 7.4 9.2 1.7 9.1 4.4 2.0 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region Aldose_epim PF01263.20 EPS26602.1 - 3.6e-62 210.4 0.0 3.9e-62 210.3 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase N_BRCA1_IG PF16158.5 EPS26604.1 - 1.9e-31 108.8 0.1 5.1e-31 107.4 0.1 1.8 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene ZZ PF00569.17 EPS26604.1 - 6.4e-23 80.3 55.9 8.8e-09 35.0 4.9 4.4 4 0 0 4 4 4 4 Zinc finger, ZZ type C1_2 PF03107.16 EPS26604.1 - 1.1 9.6 55.7 0.26 11.6 10.0 4.6 4 0 0 4 4 4 0 C1 domain Btz PF09405.10 EPS26605.1 - 9.9e-34 116.4 4.9 9.9e-34 116.4 4.9 2.2 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding RRM_1 PF00076.22 EPS26606.1 - 1.6e-21 75.9 0.5 5.8e-13 48.5 0.1 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EPS26606.1 - 4.2e-05 23.6 0.0 0.0049 17.0 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif Nup35_RRM_2 PF14605.6 EPS26606.1 - 0.025 14.6 0.0 0.43 10.6 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif HET PF06985.11 EPS26606.1 - 0.61 10.4 3.0 0.73 10.2 0.8 2.1 2 0 0 2 2 2 0 Heterokaryon incompatibility protein (HET) RRN3 PF05327.11 EPS26606.1 - 0.86 8.1 4.8 1.6 7.2 4.8 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 GNAT_acetyltr_2 PF13718.6 EPS26606.1 - 2.2 7.6 4.2 0.43 10.0 0.1 1.8 2 0 0 2 2 2 0 GNAT acetyltransferase 2 CDC45 PF02724.14 EPS26606.1 - 2.4 6.3 18.5 0.16 10.3 11.2 2.1 2 0 0 2 2 2 0 CDC45-like protein TLP-20 PF06088.11 EPS26606.1 - 4.2 7.2 10.8 0.87 9.5 4.6 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Apt1 PF10351.9 EPS26606.1 - 4.4 6.1 13.0 1.2 7.9 5.4 2.1 2 0 0 2 2 2 0 Golgi-body localisation protein domain Zip PF02535.22 EPS26606.1 - 6.1 6.0 6.2 2.7 7.1 1.1 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter NOA36 PF06524.12 EPS26606.1 - 6.4 6.0 11.7 1.1 8.6 6.3 2.0 2 0 0 2 2 2 0 NOA36 protein Ino80_Iec3 PF14612.6 EPS26607.1 - 5.1e-78 263.0 5.2 7.6e-78 262.4 5.2 1.3 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling ECR1_N PF14382.6 EPS26608.1 - 1.6e-15 56.6 1.3 3.2e-15 55.6 1.3 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 EPS26608.1 - 1.9e-05 24.9 0.8 3.8e-05 23.9 0.8 1.5 1 0 0 1 1 1 1 KH domain EXOSC1 PF10447.9 EPS26608.1 - 0.066 13.8 2.0 1.5 9.5 0.1 2.8 3 0 0 3 3 3 0 Exosome component EXOSC1/CSL4 UPF0227 PF05728.12 EPS26608.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Stonin2_N PF12016.8 EPS26608.1 - 0.14 11.6 0.1 7 6.0 0.0 2.1 2 0 0 2 2 2 0 Stonin 2 IFRD PF05004.13 EPS26609.1 - 1.1e-87 294.0 9.3 1.5e-87 293.6 9.3 1.2 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) Cnd3 PF12719.7 EPS26609.1 - 0.022 13.9 1.0 0.063 12.5 0.5 2.0 1 1 1 2 2 2 0 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 EPS26609.1 - 0.22 11.9 0.7 6 7.4 0.1 3.5 4 0 0 4 4 4 0 HEAT repeat Oxysterol_BP PF01237.18 EPS26610.1 - 3.8e-116 388.0 0.0 8.4e-116 386.9 0.0 1.6 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 EPS26610.1 - 4.5e-38 129.4 0.4 1.3e-37 127.9 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 EPS26610.1 - 6.8e-09 36.2 0.4 1.5e-08 35.1 0.1 1.8 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 EPS26610.1 - 0.0046 17.4 1.8 0.26 11.7 0.0 2.8 2 1 1 3 3 3 1 Pleckstrin homology domain PH_3 PF14593.6 EPS26610.1 - 0.079 13.1 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 PH domain EMP24_GP25L PF01105.24 EPS26610.1 - 0.12 12.4 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD SH2_2 PF14633.6 EPS26611.1 - 2.9e-87 291.6 0.0 8.3e-87 290.1 0.0 1.8 1 0 0 1 1 1 1 SH2 domain HTH_44 PF14641.6 EPS26611.1 - 1.9e-36 124.9 1.7 5.3e-36 123.6 1.7 1.7 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_7 PF14635.6 EPS26611.1 - 1.2e-31 109.1 0.0 2.7e-31 108.0 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 EPS26611.1 - 1.7e-23 83.1 0.0 5.1e-23 81.5 0.0 1.9 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.6 EPS26611.1 - 4.7e-16 59.2 18.7 4.7e-16 59.2 18.7 5.6 6 0 0 6 6 6 1 Acidic N-terminal SPT6 HHH_9 PF17674.1 EPS26611.1 - 8.8e-08 33.0 3.1 2.2e-06 28.5 3.1 3.2 1 1 0 1 1 1 1 HHH domain SH2 PF00017.24 EPS26611.1 - 3.2e-05 23.9 0.0 7.4e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.7 EPS26611.1 - 0.0068 16.6 0.0 0.022 15.0 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix motif ATP-synt_B PF00430.18 EPS26611.1 - 0.028 14.5 2.3 7.1 6.7 1.4 3.3 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) Tex_N PF09371.10 EPS26611.1 - 0.052 13.2 10.0 0.096 12.4 0.0 4.1 4 0 0 4 4 4 0 Tex-like protein N-terminal domain Pkinase PF00069.25 EPS26612.1 - 3.3e-63 213.5 0.0 4.1e-63 213.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS26612.1 - 1.9e-35 122.4 0.0 2.5e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EPS26612.1 - 6.6e-05 21.9 0.0 0.0001 21.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EPS26612.1 - 0.0033 16.8 0.0 0.006 15.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EPS26612.1 - 0.091 11.8 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 HUN PF08729.10 EPS26614.1 - 8.3e-08 32.1 0.1 2.4e-07 30.6 0.1 1.8 1 0 0 1 1 1 1 HPC2 and ubinuclein domain MAJIN PF15077.6 EPS26614.1 - 0.09 12.6 9.3 0.28 10.9 9.3 1.8 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF1764 PF08576.10 EPS26614.1 - 6.9 7.6 15.9 6.5 7.7 0.1 3.0 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF1764) RPAP1_C PF08620.10 EPS26615.1 - 3.7e-24 84.6 0.0 6.4e-24 83.9 0.0 1.4 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 EPS26615.1 - 4.5e-17 61.5 7.6 1.2e-16 60.2 7.3 1.9 2 0 0 2 2 2 1 RPAP1-like, N-terminal ANAPC1 PF12859.7 EPS26616.1 - 1.4e-33 116.2 0.4 6.2e-33 114.1 0.4 2.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 EPS26616.1 - 0.00026 21.3 0.1 0.00026 21.3 0.1 3.9 4 0 0 4 4 4 1 Proteasome/cyclosome repeat Lyase_aromatic PF00221.19 EPS26618.1 - 3e-153 510.8 9.5 4.2e-153 510.3 9.5 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase eIF2A PF08662.11 EPS26619.1 - 1.9e-84 282.4 0.0 1.1e-83 279.9 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 EPS26619.1 - 0.0059 17.4 1.7 0.42 11.6 0.1 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 EPS26619.1 - 0.12 10.8 0.0 0.28 9.7 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain Med21 PF11221.8 EPS26619.1 - 0.88 9.8 2.2 1.8 8.8 2.2 1.5 1 1 0 1 1 1 0 Subunit 21 of Mediator complex TolA_bind_tri PF16331.5 EPS26622.1 - 0.17 12.0 0.0 0.32 11.1 0.0 1.3 1 0 0 1 1 1 0 TolA binding protein trimerisation Acetyltransf_13 PF13880.6 EPS26623.1 - 2.8e-30 104.1 0.0 6.5e-30 102.9 0.0 1.7 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 EPS26623.1 - 4e-14 52.2 0.2 6.9e-14 51.4 0.2 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO EMG1 PF03587.14 EPS26624.1 - 2.8e-80 268.6 0.0 3.3e-80 268.4 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Glyoxalase PF00903.25 EPS26626.1 - 0.032 14.4 2.3 0.1 12.8 0.0 2.7 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Rick_17kDa_Anti PF05433.15 EPS26626.1 - 8.6 6.3 13.3 0.14 12.1 5.6 2.0 2 0 0 2 2 2 0 Glycine zipper 2TM domain Glyco_hydro_3_C PF01915.22 EPS26627.1 - 2.1e-49 168.3 0.0 5.8e-49 166.8 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EPS26627.1 - 1.3e-32 113.5 0.0 2.1e-32 112.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EPS26627.1 - 1.6e-17 63.4 0.0 2.9e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF953 PF06110.11 EPS26628.1 - 7.2e-13 48.2 0.0 7.7e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.6 EPS26628.1 - 0.019 14.8 0.1 0.039 13.7 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin GMC_oxred_C PF05199.13 EPS26629.1 - 3.5e-33 115.1 0.1 5.7e-33 114.5 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EPS26629.1 - 4.4e-29 101.8 0.0 2.4e-25 89.5 0.0 2.6 2 1 0 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.6 EPS26629.1 - 0.0021 18.2 0.0 0.0061 16.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EPS26629.1 - 0.014 14.7 0.0 0.026 13.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EPS26629.1 - 0.022 13.9 0.1 0.038 13.1 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 EPS26629.1 - 0.2 11.3 0.1 0.43 10.2 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UQ_con PF00179.26 EPS26630.1 - 3.2e-53 179.1 0.0 3.6e-53 179.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EPS26630.1 - 0.0039 16.9 0.0 0.0049 16.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EPS26630.1 - 0.018 15.4 0.0 0.022 15.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.13 EPS26630.1 - 0.039 13.8 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 UEV domain Acyl-CoA_dh_N PF02771.16 EPS26631.1 - 4.5e-28 98.2 0.1 9.2e-28 97.2 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 EPS26631.1 - 2.4e-25 89.5 0.6 4.3e-25 88.7 0.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EPS26631.1 - 4.1e-17 62.2 0.0 8.9e-17 61.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EPS26631.1 - 5.3e-07 30.0 0.7 5.3e-07 30.0 0.7 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Zn_clus PF00172.18 EPS26632.1 - 5.9e-09 35.9 8.3 1.3e-08 34.8 8.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPS26632.1 - 0.0078 15.3 0.5 0.023 13.7 0.5 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Foie-gras_1 PF11817.8 EPS26632.1 - 0.023 14.3 0.0 0.044 13.4 0.0 1.5 1 0 0 1 1 1 0 Foie gras liver health family 1 TF_Zn_Ribbon PF08271.12 EPS26632.1 - 5.2 6.7 6.0 11 5.6 6.0 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding XPG_N PF00752.17 EPS26633.1 - 4.2e-32 110.6 0.3 3.2e-31 107.8 0.0 2.2 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.18 EPS26633.1 - 6.7e-32 109.7 1.9 1.5e-31 108.6 0.0 2.2 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.20 EPS26633.1 - 3.6e-05 24.3 0.3 0.00027 21.5 0.0 2.4 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 EPS26633.1 - 0.065 13.9 0.0 0.19 12.4 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain Linker_histone PF00538.19 EPS26634.1 - 5.2e-31 106.8 0.5 5.2e-31 106.8 0.5 2.1 2 1 1 3 3 3 1 linker histone H1 and H5 family Glyco_hydro_18 PF00704.28 EPS26635.1 - 3.9e-66 223.9 0.9 4.6e-66 223.7 0.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 ULD PF16534.5 EPS26635.1 - 0.19 11.8 0.0 0.41 10.7 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like oligomerisation domain of SATB PIP5K PF01504.18 EPS26636.1 - 1.7e-100 335.8 0.2 6.2e-100 333.9 0.0 2.0 2 1 1 3 3 3 1 Phosphatidylinositol-4-phosphate 5-Kinase ATP-sulfurylase PF01747.17 EPS26638.1 - 2.2e-86 288.7 0.0 3.1e-86 288.2 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 EPS26638.1 - 3.3e-61 205.8 0.0 5.2e-61 205.2 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 EPS26638.1 - 2.4e-50 170.3 0.0 4.3e-50 169.5 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain CPT PF07931.12 EPS26638.1 - 0.022 14.6 0.1 0.17 11.7 0.1 2.1 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.6 EPS26638.1 - 0.044 14.3 0.0 0.095 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain EGF PF00008.27 EPS26639.1 - 0.045 14.1 7.9 0.088 13.1 7.9 1.5 1 0 0 1 1 1 0 EGF-like domain DUF997 PF06196.12 EPS26639.1 - 0.19 11.7 1.2 0.35 10.9 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF997) CDC45 PF02724.14 EPS26641.1 - 0.38 9.0 2.4 0.45 8.8 2.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SET PF00856.28 EPS26643.1 - 2.4e-12 47.6 0.3 2.4e-12 47.6 0.3 3.2 2 2 0 2 2 2 1 SET domain AWS PF17907.1 EPS26643.1 - 1.4e-08 34.6 8.5 1.4e-08 34.6 8.5 2.2 3 0 0 3 3 3 1 AWS domain DHHC PF01529.20 EPS26644.1 - 5.4e-34 117.2 8.4 5.4e-34 117.2 8.4 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase PMT PF02366.18 EPS26646.1 - 3.9e-82 275.5 17.2 7.4e-82 274.6 17.2 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EPS26646.1 - 5.6e-68 228.5 12.7 5.6e-68 228.5 12.7 2.5 3 0 0 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EPS26646.1 - 3.2e-46 157.5 0.0 6.6e-46 156.5 0.0 1.5 1 0 0 1 1 1 1 MIR domain Hydin_ADK PF17213.3 EPS26646.1 - 0.18 12.0 0.4 0.36 11.1 0.4 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain PRP21_like_P PF12230.8 EPS26647.1 - 7.6e-57 192.7 11.0 2.3e-56 191.1 11.0 1.7 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 EPS26647.1 - 9.1e-38 128.0 1.9 1.1e-19 70.2 0.0 2.4 2 0 0 2 2 2 2 Surp module zf_UBZ PF18439.1 EPS26647.1 - 0.0067 16.0 0.7 0.018 14.6 0.7 1.7 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger Sas10_Utp3 PF04000.15 EPS26648.1 - 1e-15 58.1 2.9 1.2e-15 57.8 0.0 2.3 2 1 0 2 2 2 1 Sas10/Utp3/C1D family Band_3_cyto PF07565.13 EPS26648.1 - 4 7.2 8.2 6 6.6 8.2 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Hid1 PF12722.7 EPS26648.1 - 4.8 5.2 14.8 6 4.9 14.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein ApbA_C PF08546.11 EPS26649.1 - 2e-24 86.2 0.0 3.4e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EPS26649.1 - 3.6e-24 85.1 0.0 2.4e-23 82.5 0.0 2.0 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 EPS26649.1 - 0.016 15.8 0.0 4.1 8.0 0.0 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent SET PF00856.28 EPS26650.1 - 2.3e-13 50.9 0.0 5.9e-13 49.6 0.0 1.7 1 1 0 1 1 1 1 SET domain Scm3 PF10384.9 EPS26650.1 - 2.3 8.0 5.2 6.4 6.6 0.5 3.1 3 0 0 3 3 3 0 Centromere protein Scm3 Coq4 PF05019.13 EPS26651.1 - 2.5e-96 321.3 0.0 3.1e-96 321.0 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 dsDNA_bind PF01984.20 EPS26652.1 - 7e-37 126.1 16.8 8.2e-37 125.9 16.8 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain cwf18 PF08315.12 EPS26652.1 - 0.0055 17.4 4.9 0.0073 17.0 4.9 1.1 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor CdiI_N PF18228.1 EPS26652.1 - 0.045 13.6 0.0 0.063 13.1 0.0 1.2 1 0 0 1 1 1 0 CdiI N-terminal domain DUF4615 PF15393.6 EPS26652.1 - 0.28 11.8 3.4 0.15 12.7 1.2 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4615) Sec2p PF06428.11 EPS26653.1 - 2e-29 101.4 14.8 2e-29 101.4 14.8 2.0 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF3828 PF12883.7 EPS26653.1 - 0.028 14.8 0.7 0.069 13.5 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3828) Aldedh PF00171.22 EPS26653.1 - 1.1 7.7 4.2 1.7 7.1 4.2 1.2 1 0 0 1 1 1 0 Aldehyde dehydrogenase family Golgin_A5 PF09787.9 EPS26653.1 - 1.5 8.2 19.0 2.8 7.3 19.0 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 YlqD PF11068.8 EPS26653.1 - 4.9 7.5 16.5 3 8.2 8.9 2.3 1 1 1 2 2 2 0 YlqD protein GCN5L1 PF06320.13 EPS26653.1 - 5.5 7.2 13.0 1 9.5 7.5 2.2 1 1 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) CorA PF01544.18 EPS26653.1 - 9.7 5.4 9.2 17 4.6 9.2 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF2076 PF09849.9 EPS26654.1 - 2.2e-13 50.9 12.3 2.6e-13 50.6 12.3 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 EPS26654.1 - 3.1e-05 24.0 1.2 5e-05 23.3 1.2 1.4 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 EPS26654.1 - 0.019 15.0 0.1 0.033 14.2 0.1 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, RE_NgoFVII PF09565.10 EPS26654.1 - 0.2 10.9 0.0 0.2 10.9 0.0 1.1 1 0 0 1 1 1 0 NgoFVII restriction endonuclease DUF2613 PF11021.8 EPS26654.1 - 3.2 7.9 10.1 0.092 12.9 2.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) UBX PF00789.20 EPS26655.1 - 3.1e-10 40.1 0.0 7.1e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 UBX domain Apt1 PF10351.9 EPS26655.1 - 0.42 9.4 6.8 0.58 9.0 6.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SURF1 PF02104.15 EPS26656.1 - 2.3e-46 158.3 0.0 3.3e-46 157.7 0.0 1.2 1 0 0 1 1 1 1 SURF1 family CENP-T_C PF15511.6 EPS26657.1 - 3e-45 152.8 0.1 5.5e-45 151.9 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EPS26657.1 - 3.6e-08 33.7 0.0 6.4e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 EPS26657.1 - 0.00011 22.6 0.4 0.00027 21.3 0.0 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EPS26657.1 - 0.0072 16.6 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DDE_Tnp_IS66 PF03050.14 EPS26657.1 - 0.11 11.9 0.1 0.2 11.1 0.1 1.3 1 0 0 1 1 1 0 Transposase IS66 family CMS1 PF14617.6 EPS26658.1 - 2.2e-79 266.4 7.2 4.2e-79 265.5 7.2 1.5 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 EPS26658.1 - 0.00025 20.8 0.0 0.0004 20.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWIRM-assoc_2 PF16496.5 EPS26658.1 - 1.9 7.3 6.7 2.4 7.0 6.7 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal RRM_1 PF00076.22 EPS26659.1 - 1.6e-11 43.8 1.3 2.8e-11 43.1 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BSP_II PF05432.11 EPS26659.1 - 2.2 7.9 45.2 0.33 10.6 40.2 1.8 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Mitofilin PF09731.9 EPS26659.1 - 9.8 4.9 53.5 0.35 9.6 44.9 2.0 2 0 0 2 2 2 0 Mitochondrial inner membrane protein Ras PF00071.22 EPS26660.1 - 5.2e-55 185.5 0.0 6e-55 185.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EPS26660.1 - 4.4e-21 75.3 0.0 6.4e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPS26660.1 - 6.7e-07 28.9 0.0 8.8e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family ABM PF03992.16 EPS26661.1 - 1.3e-13 50.9 0.1 2.2e-13 50.1 0.0 1.4 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase Spt5-NGN PF03439.13 EPS26661.1 - 0.034 14.0 0.1 0.049 13.5 0.1 1.3 1 0 0 1 1 1 0 Early transcription elongation factor of RNA pol II, NGN section RhoGAP PF00620.27 EPS26662.1 - 1.2e-48 164.8 0.0 3.5e-48 163.3 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 EPS26662.1 - 1.3e-12 47.8 4.1 2.1e-12 47.1 0.6 2.6 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Erp_C PF06780.11 EPS26662.1 - 0.013 15.5 0.1 0.026 14.5 0.1 1.5 1 0 0 1 1 1 0 Erp protein C-terminus FUSC PF04632.12 EPS26662.1 - 0.018 13.6 11.6 0.027 13.0 11.6 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Leu_zip PF15294.6 EPS26662.1 - 8.1 5.9 9.7 0.54 9.7 3.3 2.1 2 1 1 3 3 3 0 Leucine zipper MBA1 PF07961.11 EPS26663.1 - 4.4e-08 32.5 0.1 7.1e-08 31.8 0.1 1.3 1 0 0 1 1 1 1 MBA1-like protein Tim44 PF04280.15 EPS26663.1 - 0.12 12.5 0.5 0.25 11.4 0.5 1.5 1 1 0 1 1 1 0 Tim44-like domain EOS1 PF12326.8 EPS26664.1 - 2.4e-12 47.2 12.5 2.9e-12 46.9 10.4 2.0 1 1 1 2 2 2 1 N-glycosylation protein SUI1 PF01253.22 EPS26665.1 - 3.6e-28 97.9 4.2 4.7e-28 97.5 4.2 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 GlcNAc-1_reg PF18440.1 EPS26665.1 - 0.077 13.2 0.3 0.12 12.6 0.3 1.3 1 0 0 1 1 1 0 Putative GlcNAc-1 phosphotransferase regulatory domain UPF0139 PF03669.13 EPS26666.1 - 3.8e-09 36.3 0.6 4.6e-09 36.0 0.6 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Cons_hypoth698 PF03601.14 EPS26666.1 - 0.032 13.1 0.2 0.036 13.0 0.2 1.0 1 0 0 1 1 1 0 Conserved hypothetical protein 698 RFC1 PF08519.12 EPS26666.1 - 0.075 13.2 0.2 0.092 12.9 0.2 1.1 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain Med12 PF09497.10 EPS26667.1 - 5e-27 94.0 0.9 1.9e-26 92.1 0.9 2.1 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 RRM_1 PF00076.22 EPS26668.1 - 5.3e-10 39.0 0.0 3.1e-08 33.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CIA30 PF08547.12 EPS26669.1 - 8.9e-40 136.3 0.0 3.7e-25 88.8 0.0 2.1 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) SAICAR_synt PF01259.18 EPS26670.1 - 8.6e-98 326.9 0.0 1e-97 326.7 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase ANAPC5 PF12862.7 EPS26671.1 - 7.4e-33 112.5 5.5 2.2e-32 111.0 5.5 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.6 EPS26671.1 - 0.0084 16.4 13.4 0.99 9.7 0.5 5.7 5 2 1 6 6 6 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EPS26671.1 - 0.037 13.4 7.8 0.024 14.0 2.1 2.9 2 1 0 3 3 3 0 MalT-like TPR region TPR_2 PF07719.17 EPS26671.1 - 0.16 12.2 4.8 7.1 7.0 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 EPS26671.1 - 0.17 12.0 0.9 45 4.4 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat COX6A PF02046.15 EPS26672.1 - 2.6e-54 182.5 1.2 3.2e-54 182.2 1.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Exo_endo_phos PF03372.23 EPS26673.1 - 2.9e-11 43.4 0.0 4.4e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.12 EPS26673.1 - 5.9e-05 23.1 0.9 0.00015 21.8 0.9 1.7 1 0 0 1 1 1 1 GRF zinc finger HMG_box PF00505.19 EPS26675.1 - 9.3e-20 70.8 0.0 1.6e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EPS26675.1 - 0.00051 20.6 0.0 0.00086 19.9 0.0 1.4 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.12 EPS26675.1 - 0.022 14.7 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 CHDNT (NUC034) domain ANTH PF07651.16 EPS26676.1 - 2.9e-79 266.0 3.6 2.9e-79 265.9 0.0 2.6 2 0 0 2 2 2 1 ANTH domain I_LWEQ PF01608.17 EPS26676.1 - 3.5e-55 186.5 8.7 3.5e-55 186.5 8.7 6.3 3 2 4 7 7 7 2 I/LWEQ domain Stm1_N PF09598.10 EPS26676.1 - 3.3 8.6 7.6 0.42 11.5 2.2 2.3 2 0 0 2 2 2 0 Stm1 MMM1 PF10296.9 EPS26677.1 - 8.3e-06 25.1 0.0 1.9e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 PH_11 PF15413.6 EPS26677.1 - 0.036 14.5 0.1 0.1 13.0 0.1 1.8 1 1 0 1 1 1 0 Pleckstrin homology domain Axin_b-cat_bind PF08833.10 EPS26677.1 - 9.8 6.4 7.5 6.4 7.0 2.3 3.2 2 0 0 2 2 2 0 Axin beta-catenin binding domain polyprenyl_synt PF00348.17 EPS26678.1 - 5e-73 245.3 0.0 9e-73 244.5 0.0 1.4 1 1 0 1 1 1 1 Polyprenyl synthetase Rpn3_C PF08375.11 EPS26680.1 - 5e-27 94.1 1.2 1.9e-26 92.2 1.2 2.1 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 EPS26680.1 - 4.5e-20 72.1 0.9 2.7e-19 69.6 0.0 2.6 3 0 0 3 3 3 1 PCI domain Sigma70_r1_2 PF00140.20 EPS26680.1 - 1.3 9.1 5.2 1 9.4 2.4 2.2 2 0 0 2 2 2 0 Sigma-70 factor, region 1.2 SOG2 PF10428.9 EPS26680.1 - 5.8 6.0 11.8 8.5 5.4 11.8 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DASH_Spc34 PF08657.10 EPS26681.1 - 1.6e-44 152.6 0.5 3.2e-21 76.3 0.1 2.0 1 1 1 2 2 2 2 DASH complex subunit Spc34 DUF465 PF04325.13 EPS26681.1 - 0.0071 16.4 1.5 0.016 15.3 0.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF465) Prefoldin_2 PF01920.20 EPS26681.1 - 0.014 15.4 0.5 2.1 8.4 0.1 2.3 2 0 0 2 2 2 0 Prefoldin subunit CENP-F_leu_zip PF10473.9 EPS26681.1 - 0.08 13.0 4.3 3.4 7.7 0.4 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2406 PF10295.9 EPS26681.1 - 0.099 13.3 0.6 0.29 11.8 0.2 1.9 2 0 0 2 2 2 0 Uncharacterised protein (DUF2406) DUF3287 PF11690.8 EPS26681.1 - 0.23 11.2 1.5 13 5.6 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) TPR_MLP1_2 PF07926.12 EPS26681.1 - 0.39 10.8 3.1 0.59 10.2 0.5 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DHR10 PF18595.1 EPS26681.1 - 0.4 10.8 6.1 6.1 6.9 0.8 2.3 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain XhlA PF10779.9 EPS26681.1 - 0.42 10.8 1.9 2.5 8.4 0.2 2.3 2 0 0 2 2 2 0 Haemolysin XhlA CENP-Q PF13094.6 EPS26681.1 - 0.66 10.2 5.8 3.6 7.8 0.3 3.1 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit ABC_tran_CTD PF16326.5 EPS26681.1 - 2.5 8.4 7.2 3.7 7.9 1.3 2.6 2 0 0 2 2 2 0 ABC transporter C-terminal domain TFIID_20kDa PF03847.13 EPS26682.1 - 1.6e-22 79.8 0.0 2.7e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.24 EPS26682.1 - 0.0033 17.8 0.0 0.0033 17.8 0.0 2.9 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 GrpE PF01025.19 EPS26682.1 - 0.77 9.4 12.0 0.26 11.0 0.7 2.5 2 0 0 2 2 2 0 GrpE DUF829 PF05705.14 EPS26683.1 - 4.2e-49 167.6 0.0 4.8e-49 167.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Glyco_hydro_76 PF03663.14 EPS26684.1 - 4.6e-118 394.9 17.9 6e-118 394.5 17.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_127 PF07944.12 EPS26684.1 - 0.014 13.9 0.9 0.26 9.7 0.9 2.4 1 1 0 1 1 1 0 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_88 PF07470.13 EPS26684.1 - 0.015 14.4 14.1 0.16 11.0 0.8 2.5 1 1 1 2 2 2 0 Glycosyl Hydrolase Family 88 AA_permease_2 PF13520.6 EPS26685.1 - 5.3e-60 203.4 48.9 6.3e-60 203.2 48.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPS26685.1 - 7.3e-16 57.8 40.1 1.1e-15 57.2 40.1 1.2 1 0 0 1 1 1 1 Amino acid permease Gram_pos_anchor PF00746.21 EPS26685.1 - 0.18 11.8 0.0 0.18 11.8 0.0 2.9 4 0 0 4 4 4 0 LPXTG cell wall anchor motif Questin_oxidase PF14027.6 EPS26686.1 - 4.1e-92 309.3 3.1 5e-92 309.0 3.1 1.1 1 0 0 1 1 1 1 Questin oxidase-like Pro_CA PF00484.19 EPS26687.1 - 7.3e-51 172.5 0.1 9.5e-51 172.2 0.1 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Pro_CA PF00484.19 EPS26688.1 - 5e-32 111.3 0.0 6e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Trimer_CC PF08954.11 EPS26689.1 - 0.00038 19.9 2.2 0.0016 17.9 0.5 2.4 2 0 0 2 2 2 1 Trimerisation motif ZapB PF06005.12 EPS26689.1 - 0.014 15.8 6.0 0.027 14.9 6.0 1.5 1 0 0 1 1 1 0 Cell division protein ZapB HECT_2 PF09814.9 EPS26690.1 - 4.3e-108 361.5 0.0 5e-108 361.3 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding TauD PF02668.16 EPS26691.1 - 9.2e-60 202.7 0.5 1.2e-59 202.3 0.5 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.16 EPS26692.1 - 1e-22 80.6 19.3 1e-22 80.6 19.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EPS26692.1 - 0.018 13.9 4.4 0.028 13.3 4.4 1.4 1 0 0 1 1 1 0 MFS_1 like family DUF4256 PF14066.6 EPS26693.1 - 0.18 11.5 0.0 0.23 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4256) Gmx_para_CXXCG PF09535.10 EPS26694.1 - 1.7 7.8 4.8 4.6 6.4 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (Gmx_para_CXXCG) PI-PLC-X PF00388.19 EPS26696.1 - 8.3e-61 203.8 0.0 1.7e-60 202.8 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EPS26696.1 - 6e-39 133.0 0.2 1.4e-38 131.8 0.2 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain TFIIF_alpha PF05793.12 EPS26696.1 - 2.4 6.6 11.6 3.9 6.0 11.6 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) GST_N_3 PF13417.6 EPS26697.1 - 9.2e-08 32.4 0.0 1.9e-07 31.3 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EPS26697.1 - 1.2e-05 25.3 0.0 2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EPS26697.1 - 0.0012 19.1 0.0 0.0022 18.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Ribosomal_L37 PF08561.10 EPS26698.1 - 2.6e-43 147.4 1.2 3.9e-43 146.8 1.2 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 GDP_Man_Dehyd PF16363.5 EPS26699.1 - 2.6e-37 129.0 0.0 6.5e-37 127.7 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EPS26699.1 - 2e-36 125.7 0.0 8.2e-36 123.7 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EPS26699.1 - 1.8e-07 30.6 0.0 7.8e-06 25.2 0.0 2.3 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EPS26699.1 - 2.3e-06 27.0 0.0 0.0001 21.6 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.19 EPS26699.1 - 2.8e-06 26.6 0.0 2.9e-05 23.2 0.0 2.4 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 EPS26699.1 - 0.0012 18.8 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 EPS26699.1 - 0.0023 17.4 0.0 0.0049 16.4 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 EPS26699.1 - 0.0048 16.0 0.0 0.025 13.7 0.0 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain Pyr_redox_2 PF07992.14 EPS26699.1 - 0.0072 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Spherulin4 PF12138.8 EPS26700.1 - 3.8e-73 246.1 0.0 4.4e-73 245.9 0.0 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 Glyco_hydro_114 PF03537.13 EPS26701.1 - 1.9e-88 295.7 4.4 2.3e-88 295.4 4.4 1.1 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 TraD_N PF12615.8 EPS26701.1 - 0.061 14.1 0.0 0.62 10.9 0.0 2.5 2 1 1 3 3 3 0 F sex factor protein N terminal Polysacc_deac_1 PF01522.21 EPS26703.1 - 0.065 13.1 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Polysaccharide deacetylase FAM86 PF14904.6 EPS26704.1 - 0.083 13.0 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function Glyco_trans_1_4 PF13692.6 EPS26705.1 - 3e-12 47.1 0.0 8.5e-12 45.7 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EPS26705.1 - 9.3e-12 44.8 0.0 1.7e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3492 PF11997.8 EPS26705.1 - 0.0028 17.5 0.1 0.0098 15.7 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3492) DPPIV_N PF00930.21 EPS26706.1 - 1.6e-113 379.0 0.2 2.2e-113 378.6 0.2 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 EPS26706.1 - 3.3e-55 186.9 0.9 5.7e-55 186.1 0.9 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EPS26706.1 - 1.9e-05 24.4 0.7 0.00012 21.8 0.2 2.1 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 EPS26706.1 - 0.0024 16.6 0.0 0.021 13.5 0.0 2.2 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 EPS26706.1 - 0.019 14.2 0.0 0.18 11.0 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EPS26706.1 - 0.026 14.2 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold PAF-AH_p_II PF03403.13 EPS26706.1 - 0.03 12.8 0.0 1.8 7.0 0.0 2.1 1 1 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II BAAT_C PF08840.11 EPS26706.1 - 0.18 11.7 0.0 11 5.9 0.0 2.3 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Zn_clus PF00172.18 EPS26707.1 - 2e-09 37.4 9.1 3.7e-09 36.6 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EPS26707.1 - 3.4e-06 26.1 0.0 5.1e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain C5-epim_C PF06662.13 EPS26707.1 - 0.094 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus Cpn60_TCP1 PF00118.24 EPS26708.1 - 1.4e-148 495.6 12.2 1.6e-148 495.4 12.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family AAA PF00004.29 EPS26709.1 - 3.1e-40 137.7 0.0 5.3e-40 136.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EPS26709.1 - 8.8e-06 25.4 0.1 2e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EPS26709.1 - 0.00013 22.0 0.1 0.00062 19.8 0.0 2.1 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EPS26709.1 - 0.00015 22.0 0.0 0.0055 17.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 EPS26709.1 - 0.00051 20.2 0.0 0.0016 18.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EPS26709.1 - 0.00057 20.3 0.1 0.011 16.1 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 EPS26709.1 - 0.0015 17.7 0.0 0.0026 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 EPS26709.1 - 0.0094 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EPS26709.1 - 0.029 14.6 0.0 0.063 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EPS26709.1 - 0.031 13.8 0.0 0.095 12.2 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 EPS26709.1 - 0.051 13.7 0.0 0.095 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EPS26709.1 - 0.06 13.7 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 EPS26709.1 - 0.088 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EPS26709.1 - 0.09 12.5 0.1 0.59 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EPS26709.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EPS26709.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain FAD_binding_2 PF00890.24 EPS26710.1 - 5.5e-126 421.0 3.7 8.1e-126 420.5 3.7 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 EPS26710.1 - 9.1e-45 151.8 1.7 1.4e-44 151.2 1.7 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 EPS26710.1 - 2.2e-06 27.1 2.1 0.00092 18.5 0.9 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EPS26710.1 - 3e-05 23.3 1.2 0.024 13.7 1.9 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.17 EPS26710.1 - 0.00012 21.5 0.3 0.048 12.9 0.1 2.2 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.19 EPS26710.1 - 0.0035 16.7 0.2 0.0075 15.6 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EPS26710.1 - 0.0098 15.5 1.2 0.029 14.0 1.2 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase PAPS_reduct PF01507.19 EPS26710.1 - 0.15 12.1 0.4 0.26 11.3 0.4 1.2 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family HI0933_like PF03486.14 EPS26710.1 - 0.42 9.3 1.8 0.89 8.2 0.7 2.1 3 0 0 3 3 3 0 HI0933-like protein Adeno_E3_CR2 PF02439.15 EPS26711.1 - 0.0074 16.0 0.3 0.013 15.2 0.3 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Lyase_1 PF00206.20 EPS26712.1 - 1e-91 307.6 0.0 1.7e-91 306.9 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 EPS26712.1 - 1.9e-24 86.2 0.1 5.8e-24 84.6 0.1 1.9 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal FR47 PF08445.10 EPS26713.1 - 3.6e-06 26.9 0.0 0.0044 17.0 0.0 2.3 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_3 PF13302.7 EPS26713.1 - 0.013 16.1 0.1 0.023 15.4 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPS26713.1 - 0.031 14.5 0.0 0.06 13.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EPS26713.1 - 0.07 13.6 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EPS26713.1 - 0.2 11.6 0.0 0.33 10.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain IBD PF10416.9 EPS26715.1 - 0.024 14.6 0.5 0.037 14.0 0.5 1.3 1 0 0 1 1 1 0 Transcription-initiator DNA-binding domain IBD Terpene_synth_C PF03936.16 EPS26717.1 - 1.4e-08 34.5 0.0 2.1e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain RRM_1 PF00076.22 EPS26719.1 - 4.9e-43 144.8 0.0 1.4e-20 72.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EPS26719.1 - 0.00023 21.2 0.0 0.17 12.0 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif Alg6_Alg8 PF03155.15 EPS26720.1 - 4.3e-128 428.3 24.6 5.9e-82 276.2 10.5 2.1 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family COX17 PF05051.13 EPS26721.1 - 2.9e-22 78.7 6.9 4.6e-22 78.1 6.9 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 EPS26721.1 - 0.015 15.3 3.0 0.59 10.2 0.0 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like LRR_6 PF13516.6 EPS26722.1 - 8.7e-12 44.1 3.6 0.00043 20.1 0.0 6.9 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.7 EPS26722.1 - 7.8e-05 23.0 7.6 0.054 13.9 0.1 4.9 5 1 0 5 5 5 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EPS26722.1 - 0.0041 17.5 1.2 50 5.0 0.0 5.3 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_8 PF13855.6 EPS26722.1 - 0.014 15.1 4.1 2.8 7.8 0.0 4.4 4 1 0 4 4 4 0 Leucine rich repeat NKAP PF15692.5 EPS26722.1 - 0.39 11.5 5.4 0.76 10.5 5.4 1.4 1 0 0 1 1 1 0 NF-kappa-B-activating protein DUF2951 PF11166.8 EPS26722.1 - 0.94 9.7 6.6 2.5 8.4 6.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) SDA1 PF05285.12 EPS26722.1 - 1.9 7.8 18.6 3.1 7.1 18.6 1.3 1 0 0 1 1 1 0 SDA1 TFIIS_M PF07500.14 EPS26723.1 - 4.2e-27 94.8 0.5 8.5e-27 93.9 0.1 1.7 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 EPS26723.1 - 7e-19 67.4 5.3 1.3e-18 66.6 5.3 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 EPS26723.1 - 7.3e-11 41.9 0.3 7.3e-11 41.9 0.3 2.3 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Baculo_LEF5_C PF11792.8 EPS26723.1 - 0.011 15.3 2.1 0.015 14.9 0.1 2.0 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain ABC1 PF03109.16 EPS26725.1 - 1.1e-21 77.1 0.1 9.9e-21 74.1 0.0 2.3 2 0 0 2 2 2 1 ABC1 family APH PF01636.23 EPS26725.1 - 0.016 15.1 0.2 0.086 12.7 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family DNA_processg_A PF02481.15 EPS26725.1 - 0.044 13.0 0.1 0.17 11.1 0.0 1.8 2 0 0 2 2 2 0 DNA recombination-mediator protein A CO_deh_flav_C PF03450.17 EPS26726.1 - 0.051 13.7 0.0 0.33 11.2 0.0 2.0 2 0 0 2 2 2 0 CO dehydrogenase flavoprotein C-terminal domain Lactamase_B PF00753.27 EPS26727.1 - 2.8e-06 27.5 0.6 0.00024 21.2 0.2 2.3 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EPS26727.1 - 0.00024 20.7 0.2 0.00077 19.0 0.2 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain E1-E2_ATPase PF00122.20 EPS26735.1 - 2.3e-37 128.3 7.5 9e-37 126.3 0.6 3.8 3 2 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EPS26735.1 - 2.7e-17 63.8 0.0 7.2e-17 62.4 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EPS26735.1 - 2e-11 43.4 0.8 4.2e-11 42.4 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EPS26735.1 - 0.005 16.6 0.1 0.0099 15.6 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase GNVR PF13807.6 EPS26735.1 - 0.14 12.1 0.0 0.51 10.3 0.0 2.0 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase Pectinesterase PF01095.19 EPS26736.1 - 9.6e-29 100.0 3.1 2.9e-22 78.7 0.3 2.1 2 0 0 2 2 2 2 Pectinesterase LXG PF04740.12 EPS26738.1 - 0.13 12.0 0.4 0.23 11.2 0.4 1.3 1 0 0 1 1 1 0 LXG domain of WXG superfamily SNARE PF05739.19 EPS26739.1 - 4.2e-13 49.1 0.6 1.2e-12 47.7 0.1 2.1 2 0 0 2 2 2 1 SNARE domain Syntaxin-5_N PF11416.8 EPS26739.1 - 1.1e-06 27.7 0.1 1.1e-06 27.7 0.1 2.3 3 0 0 3 3 3 1 Syntaxin-5 N-terminal, Sly1p-binding domain KxDL PF10241.9 EPS26739.1 - 0.00017 21.8 2.2 0.21 11.9 0.1 3.1 3 0 0 3 3 3 2 Uncharacterized conserved protein Syntaxin PF00804.25 EPS26739.1 - 0.0026 17.5 9.0 0.0082 15.8 0.2 3.1 2 1 1 3 3 3 1 Syntaxin DUF4055 PF13264.6 EPS26739.1 - 0.034 14.3 0.5 1.4 9.0 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4055) SPATA48 PF15073.6 EPS26739.1 - 0.037 14.3 0.5 0.095 13.0 0.5 1.7 1 0 0 1 1 1 0 Spermatogenesis-associated protein 48 DUF4988 PF16378.5 EPS26739.1 - 0.083 12.6 4.3 8.9 5.9 0.1 3.2 2 1 1 3 3 3 0 Domain of unknown function NPV_P10 PF05531.12 EPS26739.1 - 0.12 12.8 3.6 12 6.4 0.1 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Syntaxin-18_N PF10496.9 EPS26739.1 - 0.17 12.2 2.3 0.68 10.2 0.1 2.7 3 0 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus DUF948 PF06103.11 EPS26739.1 - 0.29 11.4 1.7 3.9 7.8 0.0 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF16 PF01519.16 EPS26739.1 - 0.65 10.5 4.8 0.55 10.7 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function DUF16 SlyX PF04102.12 EPS26739.1 - 0.77 10.4 5.7 3.5 8.3 0.2 2.8 2 0 0 2 2 2 0 SlyX Prominin PF05478.11 EPS26739.1 - 0.77 7.6 2.6 4.3 5.2 0.1 2.3 2 0 0 2 2 2 0 Prominin LTXXQ PF07813.12 EPS26739.1 - 0.78 10.5 9.8 1.5 9.6 0.1 3.6 3 1 1 4 4 4 0 LTXXQ motif family protein MCPsignal PF00015.21 EPS26739.1 - 2.1 8.1 8.6 0.19 11.5 2.0 2.4 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Fungal_trans PF04082.18 EPS26740.1 - 4.5e-19 68.5 0.0 8.6e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS26740.1 - 5.6e-10 39.2 10.0 1.4e-09 37.9 10.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 EPS26741.1 - 1.3e-77 261.5 0.0 1.5e-77 261.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EPS26741.1 - 5.3e-05 22.6 0.0 0.045 13.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EPS26741.1 - 0.00032 19.9 0.0 0.00047 19.3 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Thi4 PF01946.17 EPS26741.1 - 0.0027 17.0 0.0 0.0065 15.7 0.0 1.6 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 EPS26741.1 - 0.0028 17.3 1.3 0.11 12.1 0.3 2.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EPS26741.1 - 0.0038 16.0 0.1 0.044 12.5 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 EPS26741.1 - 0.0049 17.1 0.0 0.014 15.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EPS26741.1 - 0.007 15.5 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 EPS26741.1 - 0.013 14.5 0.1 0.041 12.9 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.27 EPS26741.1 - 0.014 16.0 0.1 0.45 11.1 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase CRS1_YhbY PF01985.21 EPS26741.1 - 0.044 13.9 0.0 0.14 12.4 0.0 1.7 2 0 0 2 2 2 0 CRS1 / YhbY (CRM) domain FAD_binding_3 PF01494.19 EPS26742.1 - 8.7e-28 97.6 0.0 2e-27 96.3 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EPS26742.1 - 2.2e-10 40.7 0.1 0.00021 21.0 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPS26742.1 - 4.4e-07 29.4 0.0 0.024 13.9 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EPS26742.1 - 5.1e-05 22.5 0.1 0.00085 18.5 0.1 2.5 2 1 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EPS26742.1 - 7.6e-05 22.9 0.2 0.00019 21.6 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EPS26742.1 - 0.00016 21.1 0.0 0.18 11.1 0.0 2.6 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 EPS26742.1 - 0.00045 19.4 0.1 0.015 14.4 0.2 2.1 1 1 1 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EPS26742.1 - 0.00072 18.4 0.1 0.58 8.8 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.27 EPS26742.1 - 0.011 16.3 0.1 1.9 9.1 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EPS26742.1 - 0.024 14.6 0.2 0.57 10.2 0.0 2.8 4 0 0 4 4 4 0 FAD-NAD(P)-binding SE PF08491.10 EPS26742.1 - 0.035 13.2 0.0 0.81 8.7 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Pyr_redox_3 PF13738.6 EPS26742.1 - 0.17 11.1 0.1 0.46 9.7 0.1 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CitMHS PF03600.16 EPS26745.1 - 8.2e-13 48.2 0.2 1.9e-12 47.0 0.1 1.5 1 1 0 1 1 1 1 Citrate transporter ArsB PF02040.15 EPS26745.1 - 2.8e-10 40.1 21.7 1.7e-07 30.9 9.6 2.1 2 0 0 2 2 2 2 Arsenical pump membrane protein Mannosyl_trans3 PF11051.8 EPS26746.1 - 1.4e-66 224.7 0.0 1.6e-39 135.9 0.0 2.1 1 1 1 2 2 2 2 Mannosyltransferase putative Glyco_transf_34 PF05637.12 EPS26748.1 - 2.3e-55 187.9 1.6 2.8e-55 187.7 1.6 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Acyl_transf_3 PF01757.22 EPS26749.1 - 3.2e-20 72.5 31.2 6.1e-20 71.6 31.2 1.5 1 1 0 1 1 1 1 Acyltransferase family DUF1624 PF07786.12 EPS26749.1 - 0.0008 19.0 11.6 0.018 14.6 7.1 3.4 1 1 0 2 2 2 2 Protein of unknown function (DUF1624) DUF1218 PF06749.12 EPS26749.1 - 0.2 12.2 2.4 0.21 12.1 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) p450 PF00067.22 EPS26750.1 - 2.4e-78 264.0 0.0 3e-78 263.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Flavodoxin_1 PF00258.25 EPS26750.1 - 2.9e-29 102.1 0.0 2e-27 96.2 0.0 2.7 2 0 0 2 2 2 1 Flavodoxin FAD_binding_1 PF00667.20 EPS26750.1 - 4.5e-25 88.5 0.0 6.8e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EPS26750.1 - 9.5e-09 35.9 0.0 3.2e-08 34.2 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 EPS26750.1 - 0.00038 20.7 0.0 0.00069 19.9 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin domain Glyco_hydro_16 PF00722.21 EPS26751.1 - 8e-40 136.2 6.1 8e-40 136.2 6.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 SMC_N PF02463.19 EPS26753.1 - 6.9e-73 244.7 19.9 5e-72 241.9 19.9 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EPS26753.1 - 6e-24 84.6 0.0 2.9e-23 82.4 0.0 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EPS26753.1 - 2.2e-11 44.1 5.8 3.9e-05 23.6 0.0 4.0 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EPS26753.1 - 9.4e-09 36.1 0.0 9.4e-09 36.1 0.0 8.3 3 2 3 7 7 7 1 AAA domain AAA_15 PF13175.6 EPS26753.1 - 7e-07 29.3 8.0 7e-07 29.3 8.0 4.6 2 2 1 3 3 3 1 AAA ATPase domain DUF3584 PF12128.8 EPS26753.1 - 0.00033 18.4 49.5 0.00033 18.4 49.5 3.5 2 1 0 2 2 2 1 Protein of unknown function (DUF3584) AAA_29 PF13555.6 EPS26753.1 - 0.00034 20.3 0.0 0.00076 19.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EPS26753.1 - 0.66 10.3 3.2 26 5.1 0.0 4.2 4 1 0 4 4 4 0 AAA domain ABC_tran PF00005.27 EPS26753.1 - 1.2 9.7 0.0 1.2 9.7 0.0 6.0 3 2 0 4 4 4 0 ABC transporter ELYS PF13934.6 EPS26754.1 - 1.3e-64 218.2 0.1 1.5e-64 218.0 0.1 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly DUF2312 PF10073.9 EPS26754.1 - 0.056 13.1 0.1 0.43 10.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) zf-CCCH_4 PF18044.1 EPS26755.1 - 4.1e-08 32.8 3.2 7.6e-08 32.0 3.2 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 EPS26755.1 - 1.5e-06 27.9 2.8 3.6e-06 26.7 2.8 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EPS26755.1 - 4.5e-06 26.5 7.3 4.5e-06 26.5 7.3 1.8 2 0 0 2 2 2 1 Zinc finger domain NupH_GANP PF16768.5 EPS26755.1 - 1.2e-05 25.2 26.9 1.2e-05 25.2 26.9 3.8 1 1 2 3 3 3 1 Nucleoporin homology of Germinal-centre associated nuclear protein Torus PF16131.5 EPS26755.1 - 0.032 14.9 1.2 0.055 14.2 1.2 1.3 1 0 0 1 1 1 0 Torus domain zf-CCCH_2 PF14608.6 EPS26755.1 - 0.23 12.0 3.9 0.46 11.0 3.9 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger DUF2164 PF09932.9 EPS26755.1 - 0.31 11.1 0.4 0.49 10.5 0.4 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2164) Ribosomal_S10 PF00338.22 EPS26756.1 - 1.9e-25 89.0 0.3 2.2e-25 88.7 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e CUE PF02845.16 EPS26757.1 - 6.2e-06 25.8 0.1 1.3e-05 24.8 0.1 1.6 1 0 0 1 1 1 1 CUE domain FA_desaturase PF00487.24 EPS26758.1 - 3.5e-28 99.1 27.1 5.6e-28 98.4 27.1 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EPS26758.1 - 5.3e-12 45.7 0.0 1.2e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PGM_PMM_I PF02878.16 EPS26759.1 - 7.5e-32 109.9 0.1 1.4e-31 109.1 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 EPS26759.1 - 1e-20 74.3 0.0 2.5e-20 73.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 EPS26759.1 - 4e-16 59.2 0.2 8.1e-16 58.2 0.2 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 EPS26759.1 - 8e-09 35.6 0.0 2.4e-08 34.0 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain MFS_1 PF07690.16 EPS26760.1 - 3.6e-30 105.1 56.2 4.8e-30 104.7 52.4 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EPS26760.1 - 4.2e-14 51.9 9.2 4.2e-14 51.9 9.2 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EPS26760.1 - 2.1e-10 40.1 30.1 6.1e-07 28.6 13.7 3.0 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.6 EPS26760.1 - 1.3e-08 33.9 1.7 1.3e-08 33.9 1.7 2.9 2 1 1 3 3 3 1 MFS/sugar transport protein Pyr_redox_2 PF07992.14 EPS26761.1 - 3.7e-70 236.5 7.0 5.6e-70 235.9 7.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EPS26761.1 - 7.4e-41 138.9 0.2 2.3e-40 137.3 0.2 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EPS26761.1 - 3.9e-21 75.4 10.3 3.6e-20 72.3 1.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EPS26761.1 - 8.3e-10 38.6 12.5 1.4e-09 37.9 0.5 3.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EPS26761.1 - 1.1e-09 38.3 5.2 4.7e-05 23.5 0.7 2.4 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EPS26761.1 - 4.5e-08 32.7 6.9 8.3e-06 25.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EPS26761.1 - 1.4e-07 30.9 13.9 1.5e-06 27.5 3.9 3.0 2 2 1 3 3 3 2 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EPS26761.1 - 3.8e-07 29.6 5.5 0.00089 18.6 0.7 3.0 3 1 1 4 4 4 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 EPS26761.1 - 7.9e-07 28.5 3.3 7.9e-07 28.5 3.3 2.7 3 1 0 3 3 3 1 FAD binding domain Thi4 PF01946.17 EPS26761.1 - 2.3e-06 27.0 4.0 2.9e-05 23.4 0.1 2.4 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 EPS26761.1 - 9.8e-06 24.5 15.2 0.00085 18.1 1.9 4.1 4 0 0 4 4 4 2 HI0933-like protein DAO PF01266.24 EPS26761.1 - 1.1e-05 25.2 12.6 0.021 14.4 0.3 4.0 4 0 0 4 4 4 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 EPS26761.1 - 2.1e-05 23.8 0.5 0.079 12.1 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 EPS26761.1 - 0.02 14.1 11.3 0.39 9.9 1.6 2.9 2 1 0 2 2 2 0 FAD binding domain THF_DHG_CYH_C PF02882.19 EPS26761.1 - 0.02 14.2 0.7 0.71 9.2 0.1 3.2 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Lycopene_cycl PF05834.12 EPS26761.1 - 0.034 13.2 6.4 0.26 10.3 0.8 2.6 2 1 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 EPS26761.1 - 0.12 12.8 4.5 0.14 12.6 0.1 2.9 2 1 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 EPS26761.1 - 0.39 10.6 6.8 0.08 12.8 1.3 2.4 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FMO-like PF00743.19 EPS26761.1 - 0.53 8.6 4.7 0.92 7.8 1.1 2.6 2 1 2 4 4 4 0 Flavin-binding monooxygenase-like Trp_halogenase PF04820.14 EPS26761.1 - 1.7 7.4 7.6 1.2 7.9 0.9 2.3 2 0 0 2 2 2 0 Tryptophan halogenase Nitroreductase PF00881.24 EPS26762.1 - 7.1e-14 52.2 0.0 8.5e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family Abhydrolase_3 PF07859.13 EPS26763.1 - 1.3e-26 93.8 0.0 1.7e-26 93.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EPS26763.1 - 4.1e-10 39.1 0.0 6.3e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Sugar_tr PF00083.24 EPS26765.1 - 3.8e-87 293.0 21.5 4.5e-87 292.8 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS26765.1 - 1.6e-20 73.4 49.3 2e-16 59.9 17.3 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily Trep_Strep PF09605.10 EPS26765.1 - 0.58 10.1 0.1 0.58 10.1 0.1 3.9 3 1 0 4 4 4 0 Hypothetical bacterial integral membrane protein (Trep_Strep) OATP PF03137.20 EPS26765.1 - 2.4 6.3 11.9 1 7.6 0.2 3.0 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DNA_binding_1 PF01035.20 EPS26766.1 - 8e-28 96.4 0.1 1.1e-27 96.0 0.1 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain YadA_anchor PF03895.15 EPS26766.1 - 0.19 11.9 2.6 0.83 9.8 0.0 2.4 2 1 0 2 2 2 0 YadA-like membrane anchor domain zf-C2H2 PF00096.26 EPS26767.1 - 0.00016 21.9 10.4 0.0062 16.9 0.6 2.8 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EPS26767.1 - 0.0032 17.4 5.2 0.064 13.3 0.3 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 EPS26767.1 - 0.006 17.3 6.1 0.017 15.9 0.4 2.9 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2HE PF16278.5 EPS26767.1 - 0.009 16.4 0.2 0.079 13.4 0.0 2.2 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger Not3 PF04065.15 EPS26770.1 - 5.8e-87 291.0 20.9 8.2e-87 290.4 20.9 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 EPS26770.1 - 1.5e-44 151.2 11.3 3.4e-44 150.1 11.3 1.6 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Cep57_MT_bd PF06657.13 EPS26770.1 - 0.0019 18.6 7.6 0.29 11.6 0.4 2.7 2 0 0 2 2 2 2 Centrosome microtubule-binding domain of Cep57 Med10 PF09748.9 EPS26770.1 - 0.069 13.1 2.5 1.7 8.6 0.4 2.4 1 1 1 2 2 2 0 Transcription factor subunit Med10 of Mediator complex DUF2373 PF10180.9 EPS26770.1 - 0.15 11.9 6.9 0.039 13.8 3.2 1.9 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2373) DUF1192 PF06698.11 EPS26770.1 - 0.21 11.7 4.0 0.18 11.9 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) HALZ PF02183.18 EPS26770.1 - 0.51 10.6 3.0 1.2 9.4 0.1 2.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper Snapin_Pallidin PF14712.6 EPS26770.1 - 1.1 9.7 9.7 0.76 10.2 2.1 2.6 2 0 0 2 2 2 0 Snapin/Pallidin Cluap1 PF10234.9 EPS26770.1 - 6.3 6.1 16.3 1.6 8.0 6.8 2.2 2 0 0 2 2 2 0 Clusterin-associated protein-1 DUF641 PF04859.12 EPS26770.1 - 7.2 7.0 11.6 1.6e+02 2.6 11.6 2.4 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) RPW8 PF05659.11 EPS26770.1 - 7.6 6.2 10.2 0.7 9.6 3.4 2.3 2 1 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 LMBR1 PF04791.16 EPS26770.1 - 7.9 5.3 7.2 14 4.5 7.2 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Tyr_Deacylase PF02580.16 EPS26771.1 - 1.3e-51 174.9 0.0 1.7e-51 174.5 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Imm64 PF15600.6 EPS26771.1 - 0.14 11.8 0.3 0.29 10.8 0.2 1.5 1 1 1 2 2 2 0 Immunity protein 64 Pro_isomerase PF00160.21 EPS26772.1 - 7.2e-48 162.8 0.7 1.1e-47 162.3 0.7 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 EPS26772.1 - 6.8e-06 25.8 0.7 6.8e-06 25.8 0.7 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EPS26772.1 - 2.1e-05 24.1 0.3 2.1e-05 24.1 0.3 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 EPS26772.1 - 0.0003 20.1 1.7 0.00046 19.5 1.7 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 EPS26772.1 - 0.001 19.1 0.1 0.001 19.1 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EPS26772.1 - 0.0014 18.8 6.0 0.0014 18.8 6.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 EPS26772.1 - 0.0029 17.7 0.8 0.1 12.8 0.9 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EPS26772.1 - 0.17 11.6 10.1 2.2 8.0 0.3 3.5 4 0 0 4 4 4 0 TPR repeat TPR_14 PF13428.6 EPS26772.1 - 0.7 10.9 4.1 0.44 11.5 0.9 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat DAO PF01266.24 EPS26773.1 - 2.4e-37 129.4 0.0 2.8e-37 129.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPS26773.1 - 1.6e-06 27.6 0.0 0.066 12.4 0.0 2.8 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EPS26773.1 - 4.8e-05 22.6 0.2 0.00014 21.1 0.2 1.7 1 1 0 1 1 1 1 FAD binding domain ThiF PF00899.21 EPS26773.1 - 0.00028 20.3 0.0 0.0014 18.0 0.0 1.9 2 0 0 2 2 2 1 ThiF family GIDA PF01134.22 EPS26773.1 - 0.00042 19.5 0.0 0.55 9.2 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EPS26773.1 - 0.0035 17.5 0.0 0.0084 16.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 EPS26773.1 - 0.018 14.9 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EPS26773.1 - 0.023 14.7 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_3 PF01494.19 EPS26773.1 - 0.033 13.4 0.0 0.053 12.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.20 EPS26773.1 - 0.047 13.7 0.0 0.098 12.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 EPS26773.1 - 0.079 13.5 0.0 0.31 11.6 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FmdA_AmdA PF03069.15 EPS26774.1 - 7.5e-183 607.5 0.0 8.6e-183 607.3 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family EI24 PF07264.11 EPS26775.1 - 1.1e-11 45.3 1.0 8.9e-10 39.1 1.0 2.3 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Inp1 PF12634.7 EPS26776.1 - 3.9e-36 124.1 0.2 2.2e-35 121.6 0.0 2.2 2 0 0 2 2 2 1 Inheritance of peroxisomes protein 1 AMP-binding PF00501.28 EPS26777.1 - 4.5e-77 259.4 0.0 5.9e-77 259.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EPS26777.1 - 1.2e-19 71.0 0.1 2.7e-19 69.9 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EPS26777.1 - 4.4e-18 64.9 0.6 1.2e-17 63.6 0.6 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Transferase PF02458.15 EPS26777.1 - 6.1e-08 31.7 0.0 9.5e-08 31.1 0.0 1.2 1 0 0 1 1 1 1 Transferase family TRI5 PF06330.11 EPS26778.1 - 5.6e-32 111.0 0.8 7.4e-32 110.6 0.8 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) polyprenyl_synt PF00348.17 EPS26779.1 - 7.8e-75 251.2 0.0 9.2e-75 251.0 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase p450 PF00067.22 EPS26780.1 - 6.3e-24 84.5 0.0 8.7e-23 80.8 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 SRP14 PF02290.15 EPS26781.1 - 4.9e-25 87.7 0.0 8.6e-25 86.9 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle 14kD protein MA3 PF02847.17 EPS26782.1 - 1.2e-21 76.8 0.0 4e-21 75.1 0.0 1.9 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 EPS26782.1 - 1.1e-19 71.0 0.2 4.6e-19 68.9 0.0 2.1 2 0 0 2 2 2 1 MIF4G domain MFS_1 PF07690.16 EPS26784.1 - 1.5e-50 172.1 52.0 3.1e-50 171.1 52.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EPS26784.1 - 5.8e-18 64.6 16.6 5.8e-18 64.6 16.6 2.7 1 1 3 4 4 4 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EPS26784.1 - 3.4e-10 39.4 12.4 3.4e-10 39.4 12.4 3.1 2 2 0 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.6 EPS26784.1 - 1.5e-05 23.7 6.5 1.5e-05 23.7 6.5 3.5 1 1 0 2 2 2 2 MFS/sugar transport protein Orthopox_A43R PF06517.11 EPS26784.1 - 0.053 13.3 0.3 0.12 12.2 0.3 1.5 1 0 0 1 1 1 0 Orthopoxvirus A43R protein Phytase-like PF13449.6 EPS26785.1 - 1.6e-40 139.9 0.0 2.2e-40 139.4 0.0 1.3 1 0 0 1 1 1 1 Esterase-like activity of phytase SdiA-regulated PF06977.11 EPS26785.1 - 0.21 10.8 0.0 4.9 6.3 0.0 2.6 3 0 0 3 3 3 0 SdiA-regulated Macoilin PF09726.9 EPS26786.1 - 1.1 7.7 11.3 1.4 7.4 11.3 1.1 1 0 0 1 1 1 0 Macoilin family WDCP PF15390.6 EPS26786.1 - 1.5 7.1 7.3 2.1 6.6 7.3 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Coatomer_WDAD PF04053.14 EPS26788.1 - 7.8e-149 496.5 0.0 2.1e-148 495.1 0.0 1.7 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.11 EPS26788.1 - 1.2e-106 356.8 0.0 1.7e-106 356.4 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 EPS26788.1 - 1.1e-39 133.6 14.8 3.7e-08 33.9 0.1 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS26788.1 - 2.4e-08 34.2 0.5 0.1 12.9 0.0 5.9 3 3 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EPS26788.1 - 0.012 14.2 7.8 1.4 7.5 0.2 4.0 3 1 1 4 4 4 0 Nucleoporin Nup120/160 Evr1_Alr PF04777.13 EPS26789.1 - 1.8e-28 98.9 3.9 1.8e-28 98.9 3.9 2.0 2 0 0 2 2 2 1 Erv1 / Alr family Bd3614-deam PF14439.6 EPS26789.1 - 0.075 13.1 0.0 4.3 7.4 0.0 2.2 2 0 0 2 2 2 0 Bd3614-like deaminase Ank_2 PF12796.7 EPS26791.1 - 2.9e-09 37.4 0.0 9e-09 35.8 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) NACHT PF05729.12 EPS26791.1 - 6.8e-07 29.4 0.1 1.8e-06 27.9 0.0 1.8 2 0 0 2 2 1 1 NACHT domain Ank PF00023.30 EPS26791.1 - 4.6e-06 26.8 0.0 0.0066 16.8 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat AAA_22 PF13401.6 EPS26791.1 - 7.4e-06 26.3 1.2 0.0001 22.6 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.6 EPS26791.1 - 8.6e-05 23.0 0.3 0.00057 20.3 0.3 2.4 1 1 0 1 1 1 1 AAA ATPase domain Ank_5 PF13857.6 EPS26791.1 - 0.00042 20.6 0.1 0.04 14.3 0.0 2.8 1 1 1 2 2 2 1 Ankyrin repeats (many copies) NB-ARC PF00931.22 EPS26791.1 - 0.00086 18.6 0.0 0.0021 17.3 0.0 1.6 1 1 0 1 1 1 1 NB-ARC domain AAA_19 PF13245.6 EPS26791.1 - 0.00089 19.6 0.5 0.0032 17.8 0.5 2.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EPS26791.1 - 0.0018 18.3 0.0 0.0075 16.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain Ank_4 PF13637.6 EPS26791.1 - 0.0025 18.3 0.0 0.021 15.4 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) AAA_30 PF13604.6 EPS26791.1 - 0.0043 16.8 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain Helo_like_N PF17111.5 EPS26791.1 - 0.0061 15.9 1.2 0.011 15.1 0.0 2.0 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins MobB PF03205.14 EPS26791.1 - 0.02 14.8 0.0 0.096 12.6 0.1 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B RsgA_GTPase PF03193.16 EPS26791.1 - 0.025 14.5 0.2 0.81 9.6 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase TsaE PF02367.17 EPS26791.1 - 0.027 14.5 0.0 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 EPS26791.1 - 0.032 13.7 0.0 0.14 11.7 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region MMR_HSR1 PF01926.23 EPS26791.1 - 0.037 14.1 1.1 0.16 12.0 0.2 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase Ank_3 PF13606.6 EPS26791.1 - 0.037 14.6 0.0 7.9 7.4 0.0 3.2 2 0 0 2 2 2 0 Ankyrin repeat AAA_24 PF13479.6 EPS26791.1 - 0.052 13.3 0.1 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EPS26791.1 - 0.053 13.7 2.4 0.3 11.2 0.3 3.1 3 1 0 3 3 3 0 AAA domain AAA PF00004.29 EPS26791.1 - 0.094 13.1 2.3 1.4 9.3 2.3 2.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 EPS26791.1 - 0.096 12.9 0.1 0.35 11.1 0.0 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ResIII PF04851.15 EPS26791.1 - 0.098 12.7 0.0 0.38 10.7 0.0 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.17 EPS26791.1 - 0.1 11.7 0.0 0.33 10.0 0.0 1.8 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_29 PF13555.6 EPS26791.1 - 0.12 12.1 0.1 0.44 10.3 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EPS26791.1 - 0.14 12.7 0.0 0.5 10.9 0.0 1.9 1 0 0 1 1 1 0 ABC transporter DEK_C PF08766.11 EPS26792.1 - 0.027 14.4 0.2 0.11 12.5 0.2 2.0 1 1 0 1 1 1 0 DEK C terminal domain DUF5310 PF17237.2 EPS26793.1 - 2.4e-20 72.1 1.3 4.2e-20 71.3 1.3 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5310) EntA_Immun PF08951.10 EPS26793.1 - 0.043 14.2 0.1 0.06 13.7 0.1 1.1 1 0 0 1 1 1 0 Enterocin A Immunity Adaptin_N PF01602.20 EPS26794.1 - 9.7e-138 460.0 2.4 1.3e-137 459.6 2.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EPS26794.1 - 1.4e-64 217.1 1.2 6.6e-60 201.8 0.5 2.7 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EPS26794.1 - 2.6e-17 63.0 2.9 1.7e-06 28.3 0.0 6.1 3 2 3 6 6 6 5 HEAT repeats HEAT PF02985.22 EPS26794.1 - 2.6e-12 45.9 3.9 0.023 14.9 0.0 6.8 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 EPS26794.1 - 1.1e-05 25.9 0.3 0.64 10.6 0.0 6.1 5 1 1 6 6 6 1 HEAT-like repeat Arm PF00514.23 EPS26794.1 - 0.0015 18.5 1.7 11 6.3 0.0 5.5 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 EPS26794.1 - 0.0022 17.6 0.1 1.8 8.1 0.0 3.5 2 1 1 3 3 3 1 CLASP N terminal RTP1_C1 PF10363.9 EPS26794.1 - 0.017 15.3 0.7 2.8 8.1 0.0 4.1 2 2 2 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 RIX1 PF08167.12 EPS26794.1 - 0.063 13.0 0.2 5.8 6.6 0.0 3.0 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis Sec7_N PF12783.7 EPS26794.1 - 0.15 11.9 0.5 0.71 9.8 0.1 2.5 2 0 0 2 2 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal CAAP1 PF15335.6 EPS26794.1 - 0.89 10.1 3.3 0.62 10.6 0.1 2.4 3 0 0 3 3 3 0 Caspase activity and apoptosis inhibitor 1 ADH_N PF08240.12 EPS26795.1 - 3.3e-22 78.4 3.7 5.5e-22 77.7 3.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPS26795.1 - 9.4e-17 61.2 0.0 1.7e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPS26795.1 - 4.2e-09 37.6 0.0 6.8e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EPS26795.1 - 0.00055 19.3 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EPS26795.1 - 0.0028 17.1 0.0 0.0041 16.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GP70 PF17429.2 EPS26795.1 - 0.07 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Gene product 70 Thr_synth_N PF14821.6 EPS26796.1 - 8.3e-30 102.8 0.0 5.6e-29 100.2 0.0 2.3 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 EPS26796.1 - 2.6e-17 63.2 0.0 9.7e-17 61.3 0.0 1.8 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Collagen PF01391.18 EPS26797.1 - 0.00027 20.6 64.0 1.8e+04 -23.9 64.0 3.7 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) RIFIN PF02009.16 EPS26798.1 - 5.5 6.8 6.2 6.1 6.6 6.2 1.1 1 0 0 1 1 1 0 Rifin DNA_primase_S PF01896.19 EPS26799.1 - 1.3e-62 210.9 0.1 1.9e-62 210.4 0.1 1.2 1 0 0 1 1 1 1 DNA primase small subunit MAM33 PF02330.16 EPS26800.1 - 6e-65 219.1 3.9 7e-65 218.9 3.9 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein Tma16 PF11176.8 EPS26801.1 - 2.4e-51 173.4 1.8 2.9e-51 173.2 1.8 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 XPG_I PF00867.18 EPS26802.1 - 6.1e-25 87.4 0.1 1.5e-24 86.2 0.1 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 EPS26802.1 - 3.6e-22 78.7 0.0 1.8e-21 76.5 0.0 2.1 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I_2 PF12813.7 EPS26802.1 - 8.8e-05 22.1 0.0 0.0002 20.9 0.0 1.6 1 0 0 1 1 1 1 XPG domain containing TPR_2 PF07719.17 EPS26802.1 - 0.14 12.3 0.0 0.45 10.7 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Fig1 PF12351.8 EPS26803.1 - 1.7e-59 200.9 4.6 1.7e-59 200.9 4.6 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 EPS26803.1 - 2.7e-06 27.2 9.5 4.4e-06 26.5 9.5 1.4 1 0 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.13 EPS26803.1 - 9.6e-05 21.6 3.5 9.6e-05 21.6 3.5 1.8 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) DUF2207 PF09972.9 EPS26803.1 - 0.073 11.8 11.8 0.32 9.7 0.2 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF751 PF05421.11 EPS26803.1 - 0.65 10.8 0.2 0.65 10.8 0.2 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF751) ATP-synt_8 PF00895.20 EPS26803.1 - 7.5 7.1 0.0 7.5 7.1 0.0 3.4 4 0 0 4 4 4 0 ATP synthase protein 8 HAD_SAK_1 PF10307.9 EPS26804.1 - 1.9e-76 256.4 0.0 3e-76 255.7 0.0 1.3 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins FoP_duplication PF13865.6 EPS26804.1 - 2.2 8.9 19.5 0.15 12.6 12.8 2.3 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 zf-RING_2 PF13639.6 EPS26805.1 - 5.3e-08 33.1 9.2 8.7e-08 32.4 9.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EPS26805.1 - 1.6e-06 27.8 3.6 2.4e-06 27.3 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EPS26805.1 - 2.6e-06 27.2 9.7 4.1e-06 26.5 9.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPS26805.1 - 1.6e-05 24.7 8.5 2.5e-05 24.0 8.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EPS26805.1 - 0.00039 20.6 10.2 0.0035 17.6 10.2 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EPS26805.1 - 0.13 12.3 0.9 0.33 11.0 0.9 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-MIZ PF02891.20 EPS26805.1 - 0.13 12.0 5.8 0.23 11.2 5.8 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_UBOX PF13445.6 EPS26805.1 - 0.15 12.1 6.2 0.15 12.1 4.9 1.8 1 1 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 EPS26805.1 - 0.44 10.4 7.2 0.71 9.8 7.2 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EPS26805.1 - 1.6 8.7 5.4 2.8 8.0 5.4 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Drc1-Sld2 PF11719.8 EPS26806.1 - 5.8e-111 372.2 20.7 6.9e-111 372.0 20.7 1.1 1 0 0 1 1 1 1 DNA replication and checkpoint protein Beta-lactamase PF00144.24 EPS26807.1 - 3.9e-52 177.5 0.0 5.4e-52 177.1 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 EPS26807.1 - 1.3e-15 57.7 0.0 2.1e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Suc_Fer-like PF06999.12 EPS26808.1 - 2.9e-66 223.1 0.0 3.4e-66 222.8 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Fungal_trans PF04082.18 EPS26810.1 - 2.9e-10 39.6 1.1 4.6e-10 39.0 1.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS26810.1 - 1e-08 35.1 7.7 2e-08 34.2 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_43 PF04616.14 EPS26811.1 - 2.6e-36 125.4 2.3 3.3e-36 125.1 2.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 FMO-like PF00743.19 EPS26812.1 - 5.4e-27 94.4 0.0 8.6e-11 40.9 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EPS26812.1 - 2.9e-12 46.5 0.9 2.1e-09 37.0 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EPS26812.1 - 5.5e-09 35.7 0.0 0.0031 16.8 0.0 3.0 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPS26812.1 - 8.7e-06 25.9 0.0 2.6e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EPS26812.1 - 0.0004 20.4 0.1 0.016 15.2 0.0 2.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 EPS26812.1 - 0.00042 19.6 0.3 0.029 13.5 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 EPS26812.1 - 0.0094 15.2 0.1 0.021 14.1 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EPS26812.1 - 0.1 11.3 1.3 0.23 10.1 0.6 1.8 2 0 0 2 2 2 0 HI0933-like protein Pirin PF02678.16 EPS26813.1 - 2.8e-23 82.0 0.8 7.6e-23 80.5 0.8 1.7 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.11 EPS26813.1 - 2.2e-07 30.5 0.9 6.5e-05 22.6 0.2 3.6 3 2 0 3 3 3 1 Cupin domain Cupin_3 PF05899.12 EPS26813.1 - 0.004 16.8 0.3 8.6 6.1 0.0 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF861) 2OG-FeII_Oxy PF03171.20 EPS26813.1 - 0.15 12.6 0.0 0.62 10.6 0.0 2.1 2 1 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.18 EPS26814.1 - 3.5e-14 52.5 0.0 6e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS26814.1 - 5.9e-09 35.9 13.3 1.1e-08 35.0 13.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_2 PF02230.16 EPS26814.1 - 0.17 11.7 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase NAD_binding_10 PF13460.6 EPS26815.1 - 1.5e-14 54.3 0.0 1.9e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 EPS26815.1 - 0.043 13.3 0.0 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase ADH_zinc_N PF00107.26 EPS26815.1 - 0.046 13.7 0.0 0.18 11.8 0.0 1.8 1 1 0 2 2 2 0 Zinc-binding dehydrogenase SCO1-SenC PF02630.14 EPS26816.1 - 5.2e-48 162.4 0.0 8.1e-48 161.7 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 EPS26816.1 - 0.00039 20.3 0.1 0.00088 19.2 0.1 1.6 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 EPS26816.1 - 0.013 15.8 0.0 0.042 14.2 0.0 1.9 1 1 0 1 1 1 0 Thioredoxin-like Alpha-amylase PF00128.24 EPS26817.1 - 1.5e-114 383.0 3.6 2.7e-114 382.2 3.6 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain MoaE PF02391.17 EPS26817.1 - 2.4e-34 118.0 0.0 4.3e-34 117.2 0.0 1.4 1 0 0 1 1 1 1 MoaE protein Malt_amylase_C PF16657.5 EPS26817.1 - 2.4e-06 27.6 0.0 5.9e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 EPS26817.1 - 0.0069 15.5 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Cyc-maltodext_C PF10438.9 EPS26817.1 - 0.011 15.8 0.0 0.026 14.6 0.0 1.6 1 0 0 1 1 1 0 Cyclo-malto-dextrinase C-terminal domain RVT_thumb PF06817.14 EPS26817.1 - 0.16 11.8 0.1 0.86 9.5 0.0 2.2 2 0 0 2 2 2 0 Reverse transcriptase thumb domain RRM_1 PF00076.22 EPS26818.1 - 5.9e-13 48.4 0.1 8.6e-06 25.5 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.23 EPS26818.1 - 4.9e-12 45.5 0.5 1.3e-11 44.1 0.5 1.8 1 0 0 1 1 1 1 G-patch domain zf-RanBP PF00641.18 EPS26818.1 - 5.4e-09 35.2 2.6 9.8e-09 34.4 2.6 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others G-patch_2 PF12656.7 EPS26818.1 - 0.00043 20.3 0.9 0.00043 20.3 0.9 2.3 2 0 0 2 2 2 1 G-patch domain HGTP_anticodon PF03129.20 EPS26818.1 - 0.17 12.1 0.3 0.69 10.1 0.0 2.2 3 0 0 3 3 3 0 Anticodon binding domain Antimicrobial10 PF08105.11 EPS26818.1 - 0.21 11.7 1.5 0.44 10.7 1.5 1.5 1 0 0 1 1 1 0 Metchnikowin family DUF3433 PF11915.8 EPS26820.1 - 2.5e-32 111.2 19.0 6e-23 81.1 4.3 3.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3433) SUR7 PF06687.12 EPS26821.1 - 3e-26 92.4 12.5 4.1e-26 91.9 12.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family SCIMP PF15050.6 EPS26821.1 - 0.021 15.3 0.0 0.059 13.8 0.0 1.9 1 0 0 1 1 1 0 SCIMP protein DUF2298 PF10060.9 EPS26821.1 - 0.043 12.6 1.3 0.064 12.0 1.3 1.2 1 0 0 1 1 1 0 Uncharacterized membrane protein (DUF2298) Ion_trans_2 PF07885.16 EPS26822.1 - 1.2e-27 95.6 26.8 4.8e-17 61.7 6.6 3.4 3 0 0 3 3 3 2 Ion channel Ion_trans PF00520.31 EPS26822.1 - 0.00032 20.0 2.4 0.00032 20.0 2.4 2.7 2 1 0 2 2 2 1 Ion transport protein IRK PF01007.20 EPS26822.1 - 6.4 6.6 6.8 2.2e+02 1.6 6.8 2.7 1 1 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain Yae1_N PF09811.9 EPS26825.1 - 3e-12 46.0 0.2 5.5e-12 45.2 0.2 1.5 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Romo1 PF10247.9 EPS26825.1 - 0.061 13.7 0.6 0.13 12.7 0.6 1.5 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 SGL PF08450.12 EPS26826.1 - 2.5e-24 86.2 0.3 6.3e-24 84.9 0.3 1.7 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Str_synth PF03088.16 EPS26826.1 - 4.1e-05 23.6 0.0 0.00018 21.6 0.0 2.0 1 1 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.20 EPS26826.1 - 0.00036 20.7 0.1 0.0072 16.5 0.0 2.4 2 0 0 2 2 2 1 Arylesterase PD40 PF07676.12 EPS26826.1 - 0.051 13.5 0.1 0.26 11.3 0.1 2.3 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat DUF2335 PF10097.9 EPS26827.1 - 0.096 12.7 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2335) Acatn PF13000.7 EPS26829.1 - 1.6e-164 548.5 16.7 5.3e-82 276.1 6.8 3.1 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 DUF3951 PF13131.6 EPS26829.1 - 0.026 14.7 0.5 0.12 12.6 0.5 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) CENP-O PF09496.10 EPS26830.1 - 3.8e-68 229.6 0.0 7e-68 228.8 0.0 1.4 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component Fungal_TACC PF12709.7 EPS26831.1 - 1.7 9.1 10.3 0.098 13.1 3.0 2.5 2 0 0 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Abhydrolase_3 PF07859.13 EPS26832.1 - 2.7e-38 132.0 0.0 3.4e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EPS26832.1 - 3.3e-08 33.3 0.0 1.3e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EPS26832.1 - 0.00014 22.6 1.9 0.00019 22.1 1.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.12 EPS26832.1 - 0.00055 18.7 0.0 0.0046 15.7 0.0 1.9 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) DLH PF01738.18 EPS26832.1 - 0.00057 19.5 0.0 0.0031 17.1 0.0 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family DUF2974 PF11187.8 EPS26832.1 - 0.00073 19.2 0.0 0.0011 18.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Esterase PF00756.20 EPS26832.1 - 0.0055 16.4 0.0 1.8 8.1 0.0 2.2 2 0 0 2 2 2 2 Putative esterase BAAT_C PF08840.11 EPS26832.1 - 0.0095 15.9 0.0 0.018 14.9 0.0 1.4 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Chlorophyllase2 PF12740.7 EPS26832.1 - 0.014 14.3 0.0 0.026 13.5 0.0 1.5 1 1 0 1 1 1 0 Chlorophyllase enzyme Peptidase_S15 PF02129.18 EPS26832.1 - 0.023 14.3 0.0 2.6 7.6 0.0 2.2 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.16 EPS26832.1 - 0.025 14.4 0.0 0.057 13.2 0.0 1.6 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 EPS26832.1 - 0.082 12.5 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Chlorophyllase PF07224.11 EPS26832.1 - 0.17 10.9 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Hydrolase_4 PF12146.8 EPS26832.1 - 0.17 11.1 0.0 0.41 9.9 0.0 1.6 1 1 0 1 1 1 0 Serine aminopeptidase, S33 Thioesterase PF00975.20 EPS26832.1 - 0.2 11.7 0.2 0.38 10.8 0.1 1.4 2 0 0 2 2 2 0 Thioesterase domain Atg29_N PF18388.1 EPS26833.1 - 7.9e-28 96.1 0.6 1.5e-27 95.2 0.6 1.5 1 0 0 1 1 1 1 Atg29 N-terminal domain DFP PF04127.15 EPS26834.1 - 1.2e-13 51.3 0.0 1.2e-05 25.2 0.0 3.2 3 0 0 3 3 3 3 DNA / pantothenate metabolism flavoprotein Fringe PF02434.16 EPS26835.1 - 2.6e-09 36.9 0.1 1.5e-07 31.1 0.1 2.9 2 1 0 2 2 2 1 Fringe-like PAN_4 PF14295.6 EPS26835.1 - 0.0033 17.3 0.8 0.0081 16.0 0.8 1.6 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 EPS26835.1 - 0.0035 17.3 1.1 0.0067 16.4 1.1 1.4 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.12 EPS26835.1 - 0.54 10.1 2.7 1.1 9.2 2.7 1.4 1 0 0 1 1 1 0 PAN-like domain Polysacc_deac_1 PF01522.21 EPS26836.1 - 1.1e-18 67.3 0.0 1.9e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 EPS26836.1 - 0.031 13.9 0.0 0.067 12.8 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) PGA2 PF07543.12 EPS26836.1 - 0.23 11.4 0.8 0.48 10.4 0.8 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 DEAD PF00270.29 EPS26837.1 - 4.3e-43 147.1 0.0 6.5e-43 146.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPS26837.1 - 5.6e-25 87.8 0.0 2.7e-24 85.6 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EPS26837.1 - 0.0038 16.0 0.0 0.0055 15.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.15 EPS26837.1 - 0.019 14.9 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit UTP25 PF06862.12 EPS26837.1 - 0.11 11.2 0.0 8.3 5.1 0.0 2.4 3 0 0 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 CMS1 PF14617.6 EPS26837.1 - 0.25 10.6 0.0 0.46 9.8 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Fumble PF03630.14 EPS26838.1 - 2e-142 474.2 0.3 2.5e-142 473.9 0.3 1.1 1 0 0 1 1 1 1 Fumble GPI2 PF06432.11 EPS26839.1 - 8.2e-133 442.1 1.0 9.5e-133 441.9 1.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Glyco_hydro_18 PF00704.28 EPS26840.1 - 3.1e-82 276.8 0.4 3.7e-82 276.6 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 EPS26840.1 - 3.7e-07 30.5 20.3 7.1e-07 29.6 20.3 1.5 1 0 0 1 1 1 1 Chitin recognition protein Aldedh PF00171.22 EPS26841.1 - 1e-157 525.4 0.1 1.1e-157 525.2 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FSH1 PF03959.13 EPS26842.1 - 4.5e-40 137.6 0.0 5.2e-40 137.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) BAAT_C PF08840.11 EPS26842.1 - 0.011 15.6 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal IucA_IucC PF04183.12 EPS26842.1 - 0.021 14.4 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 IucA / IucC family DLH PF01738.18 EPS26842.1 - 0.048 13.2 0.0 0.35 10.4 0.0 1.9 1 1 0 1 1 1 0 Dienelactone hydrolase family Sec62 PF03839.16 EPS26843.1 - 0.11 12.0 1.1 0.26 10.8 1.1 1.7 1 1 0 1 1 1 0 Translocation protein Sec62 FAD_binding_4 PF01565.23 EPS26844.1 - 2.4e-20 72.7 2.5 4.4e-20 71.8 2.5 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EPS26844.1 - 6.8e-09 35.7 0.1 1.7e-08 34.4 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like DUF2371 PF10177.9 EPS26845.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Amidohydro_2 PF04909.14 EPS26846.1 - 1.2e-09 38.4 0.1 4.4e-09 36.5 0.0 2.0 2 1 0 2 2 2 1 Amidohydrolase Aldedh PF00171.22 EPS26847.1 - 1e-159 532.0 0.2 1.1e-159 531.8 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EPS26847.1 - 0.00094 18.7 0.0 0.16 11.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) LuxC PF05893.14 EPS26847.1 - 0.0071 15.4 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) NadA PF02445.16 EPS26847.1 - 0.022 13.9 0.0 0.052 12.7 0.0 1.5 2 0 0 2 2 2 0 Quinolinate synthetase A protein MFS_1 PF07690.16 EPS26850.1 - 7.9e-20 71.1 28.4 7.9e-20 71.1 28.4 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS26850.1 - 3.6e-05 22.8 29.9 0.00068 18.6 29.9 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter Peptidase_M56 PF05569.11 EPS26850.1 - 0.0041 16.4 0.2 0.092 11.9 0.0 2.2 2 0 0 2 2 2 1 BlaR1 peptidase M56 DUF5336 PF17270.2 EPS26850.1 - 0.14 11.7 5.4 0.73 9.4 0.1 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5336) DUF5040 PF16443.5 EPS26851.1 - 0.055 12.9 0.0 0.055 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5040) Axin_b-cat_bind PF08833.10 EPS26851.1 - 3.6 7.8 10.2 4.5 7.4 0.5 3.2 3 0 0 3 3 3 0 Axin beta-catenin binding domain Zn_clus PF00172.18 EPS26852.1 - 1.2e-06 28.5 9.6 1.2e-06 28.5 9.6 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EPS26853.1 - 4.3e-35 121.3 28.0 4.3e-35 121.3 28.0 2.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS26853.1 - 4.4e-13 48.9 8.9 4.4e-13 48.9 8.9 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 EPS26853.1 - 0.0024 16.4 2.5 0.0024 16.4 2.5 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF3784 PF12650.7 EPS26853.1 - 0.0051 17.0 1.4 0.0051 17.0 1.4 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF3784) FA_desaturase PF00487.24 EPS26853.1 - 7.4 6.3 20.7 0.22 11.3 2.4 3.4 2 2 1 3 3 3 0 Fatty acid desaturase UPF0016 PF01169.19 EPS26854.1 - 8e-42 141.4 25.8 9.1e-22 77.2 9.7 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Myb_DNA-binding PF00249.31 EPS26855.1 - 1.1e-07 31.9 0.1 2.5e-07 30.8 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EPS26855.1 - 0.00031 20.9 0.1 0.001 19.3 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain SLIDE PF09111.10 EPS26855.1 - 0.0013 18.8 0.0 0.0029 17.6 0.0 1.6 1 0 0 1 1 1 1 SLIDE SANT_DAMP1_like PF16282.5 EPS26855.1 - 0.045 13.9 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 WSC PF01822.19 EPS26856.1 - 4.8e-12 45.9 4.9 4.8e-12 45.9 4.9 1.8 2 1 0 2 2 2 1 WSC domain Peptidase_M20 PF01546.28 EPS26857.1 - 8.2e-30 104.0 0.0 2.1e-29 102.7 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EPS26857.1 - 4.4e-09 36.2 0.0 9.9e-09 35.1 0.0 1.6 1 1 0 1 1 1 1 Peptidase dimerisation domain DUF5127 PF17168.4 EPS26858.1 - 4.2e-85 285.1 5.4 7.6e-85 284.3 5.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF4965 PF16335.5 EPS26858.1 - 3e-78 261.4 1.5 5.6e-78 260.6 1.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF1793 PF08760.11 EPS26858.1 - 3.3e-69 232.6 0.1 3.3e-69 232.6 0.1 2.4 2 1 1 3 3 3 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 EPS26858.1 - 1e-07 31.4 0.7 3.8e-07 29.6 0.7 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4964) Phage_T4_gp36 PF03903.13 EPS26858.1 - 0.47 10.4 5.3 0.7 9.9 0.3 2.6 2 0 0 2 2 2 0 Phage T4 tail fibre Annexin PF00191.20 EPS26860.1 - 5e-13 48.9 5.0 0.00038 20.5 0.1 4.4 4 0 0 4 4 4 4 Annexin Septin PF00735.18 EPS26861.1 - 5.4e-34 117.7 0.0 5.2e-13 48.9 0.0 3.1 3 0 0 3 3 3 3 Septin MMR_HSR1 PF01926.23 EPS26861.1 - 1.3e-05 25.3 0.0 3.8e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EPS26861.1 - 0.021 14.9 0.1 0.085 12.9 0.0 2.1 2 0 0 2 2 2 0 Dynamin family Spem1 PF15670.5 EPS26861.1 - 0.037 13.6 3.5 0.69 9.4 0.0 2.9 2 1 1 3 3 3 0 Spermatid maturation protein 1 FtsK_SpoIIIE PF01580.18 EPS26861.1 - 0.078 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.6 EPS26861.1 - 0.091 13.2 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 EPS26861.1 - 0.15 12.3 0.1 1.9 8.7 0.0 2.5 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Vps62 PF06101.11 EPS26862.1 - 1.6e-11 43.2 1.2 1.4e-09 36.8 0.2 2.2 2 0 0 2 2 2 2 Vacuolar protein sorting-associated protein 62 DOPA_dioxygen PF08883.11 EPS26863.1 - 5.2e-42 142.4 0.1 6.7e-42 142.0 0.1 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family Prefoldin PF02996.17 EPS26865.1 - 0.0041 17.0 1.7 0.0041 17.0 1.7 3.1 2 2 0 2 2 2 1 Prefoldin subunit DUF948 PF06103.11 EPS26865.1 - 0.015 15.6 2.2 0.022 15.0 0.4 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Baculo_PEP_C PF04513.12 EPS26865.1 - 0.032 14.3 3.1 0.083 12.9 0.5 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus RcpB PF16971.5 EPS26865.1 - 0.055 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Rough colony protein B, tight adherence - tad - subunit Fez1 PF06818.15 EPS26865.1 - 0.37 11.2 23.4 1.2 9.5 19.4 2.4 2 1 0 2 2 1 0 Fez1 Med21 PF11221.8 EPS26865.1 - 0.78 10.0 14.5 1.1 9.5 2.3 2.4 2 0 0 2 2 2 0 Subunit 21 of Mediator complex DUF1664 PF07889.12 EPS26865.1 - 1.1 9.2 7.2 0.17 11.9 2.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.11 EPS26865.1 - 1.7 7.5 20.8 2.2 7.1 7.1 2.2 1 1 0 2 2 2 0 Spc7 kinetochore protein BLOC1_2 PF10046.9 EPS26865.1 - 2.6 8.4 8.7 0.78 10.1 2.5 3.0 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2203 PF09969.9 EPS26865.1 - 5 7.9 9.8 13 6.5 2.7 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) TMPIT PF07851.13 EPS26865.1 - 8.6 5.5 9.0 0.96 8.6 0.7 2.3 3 0 0 3 3 3 0 TMPIT-like protein T3SSipB PF16535.5 EPS26865.1 - 8.7 6.8 9.8 47 4.4 9.0 2.0 1 1 1 2 2 2 0 Type III cell invasion protein SipB GrpE PF01025.19 EPS26865.1 - 8.8 6.0 15.0 0.32 10.7 1.9 2.6 2 1 0 2 2 2 0 GrpE S4 PF01479.25 EPS26866.1 - 2e-12 46.6 0.5 2e-12 46.6 0.5 2.3 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 EPS26866.1 - 5.8e-06 27.1 0.2 1.1e-05 26.3 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain Ribosomal_L21e PF01157.18 EPS26867.1 - 5.8e-47 157.7 4.7 5.8e-47 157.7 4.7 1.5 2 0 0 2 2 2 1 Ribosomal protein L21e Thioredoxin PF00085.20 EPS26868.1 - 2.4e-27 94.9 0.0 2.9e-27 94.7 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 EPS26868.1 - 7.1e-06 25.8 0.0 7.8e-06 25.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EPS26868.1 - 6.6e-05 23.3 0.1 0.00023 21.6 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EPS26868.1 - 0.00013 22.2 0.0 0.00023 21.4 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 EPS26868.1 - 0.0041 17.0 0.0 0.0051 16.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 EPS26868.1 - 0.005 16.2 0.0 0.0053 16.1 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 EPS26868.1 - 0.0072 16.1 0.0 0.019 14.7 0.0 1.5 1 1 1 2 2 2 1 Redoxin TraF PF13728.6 EPS26868.1 - 0.0076 16.1 0.0 0.0086 15.9 0.0 1.0 1 0 0 1 1 1 1 F plasmid transfer operon protein Phosducin PF02114.16 EPS26868.1 - 0.026 13.5 0.0 0.03 13.3 0.0 1.1 1 0 0 1 1 1 0 Phosducin HrcA_DNA-bdg PF03444.15 EPS26868.1 - 0.084 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding ANT PF03374.14 EPS26868.1 - 0.17 12.2 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Phage antirepressor protein KilAC domain RRM_1 PF00076.22 EPS26869.1 - 0.015 15.1 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SecE PF00584.20 EPS26870.1 - 3.6e-14 52.4 0.1 4.4e-14 52.1 0.1 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex WD40 PF00400.32 EPS26871.1 - 4e-15 55.9 21.3 0.0028 18.5 0.5 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat PQQ_3 PF13570.6 EPS26871.1 - 0.0014 19.0 0.5 1.2 9.7 0.0 3.6 3 0 0 3 3 3 1 PQQ-like domain Cytochrom_D1 PF02239.16 EPS26871.1 - 0.0018 16.9 2.7 0.38 9.2 0.1 3.8 4 0 0 4 4 4 2 Cytochrome D1 heme domain ANAPC4_WD40 PF12894.7 EPS26871.1 - 0.0099 16.2 0.0 0.31 11.4 0.0 3.2 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EPS26871.1 - 0.044 12.4 0.0 0.083 11.5 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 PX PF00787.24 EPS26872.1 - 1.2e-27 96.1 0.2 1.5e-27 95.8 0.2 1.1 1 0 0 1 1 1 1 PX domain Myb_DNA-bind_6 PF13921.6 EPS26873.1 - 2.9e-17 62.7 0.0 2.7e-07 30.7 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EPS26873.1 - 3.3e-16 59.2 0.1 1.5e-08 34.7 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EPS26873.1 - 0.0014 18.6 0.0 0.44 10.6 0.0 2.3 2 0 0 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 EPS26873.1 - 0.15 12.3 0.0 1.3 9.2 0.0 2.0 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 RasGEF PF00617.19 EPS26875.1 - 0.00071 19.8 0.1 0.0073 16.5 0.0 2.2 2 0 0 2 2 2 1 RasGEF domain Ribosomal_S4e PF00900.20 EPS26877.1 - 2.2e-38 130.0 0.2 4.6e-38 129.0 0.2 1.6 1 0 0 1 1 1 1 Ribosomal family S4e 40S_S4_C PF16121.5 EPS26877.1 - 3.6e-24 84.1 0.0 6.3e-24 83.4 0.0 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 EPS26877.1 - 1.1e-17 63.8 5.6 2.2e-17 62.9 5.6 1.5 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 EPS26877.1 - 6.7e-07 28.9 0.0 1.3e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 EPS26877.1 - 0.0006 19.7 4.0 0.0008 19.3 0.4 3.2 3 0 0 3 3 3 1 KOW motif Semialdhyde_dhC PF02774.18 EPS26878.1 - 1.2e-33 116.7 0.0 1.6e-33 116.3 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 EPS26878.1 - 6.9e-29 100.7 0.0 1.6e-28 99.5 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DUF739 PF05339.11 EPS26878.1 - 0.042 14.0 0.0 1 9.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF739) Sacchrp_dh_NADP PF03435.18 EPS26878.1 - 0.069 13.4 0.0 0.33 11.2 0.0 2.0 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DXP_reductoisom PF02670.16 EPS26878.1 - 0.082 13.6 0.0 0.17 12.6 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase FAD-oxidase_C PF02913.19 EPS26879.1 - 3.8e-64 216.7 0.0 5e-64 216.3 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EPS26879.1 - 2.1e-36 124.7 0.0 4.9e-36 123.5 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain SepSecS PF05889.13 EPS26879.1 - 0.083 11.6 0.0 0.17 10.5 0.0 1.5 2 0 0 2 2 2 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS DUF4618 PF15397.6 EPS26880.1 - 0.0038 16.7 10.8 0.0038 16.7 10.8 3.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4618) Golgin_A5 PF09787.9 EPS26880.1 - 0.1 12.0 55.0 0.024 14.1 18.9 2.5 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF724 PF05266.14 EPS26880.1 - 1.9 8.3 42.5 1.1 9.1 8.2 3.5 1 1 1 3 3 3 0 Protein of unknown function (DUF724) CENP-F_leu_zip PF10473.9 EPS26880.1 - 2.4 8.2 60.0 6 6.9 5.9 4.5 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Bacillus_HBL PF05791.11 EPS26880.1 - 3.6 7.4 25.2 0.47 10.3 0.1 4.5 2 1 4 6 6 6 0 Bacillus haemolytic enterotoxin (HBL) GAS PF13851.6 EPS26880.1 - 3.9 6.8 56.2 0.3 10.4 10.1 3.5 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding EB1 PF03271.17 EPS26880.1 - 6.6 7.1 9.0 2.9 8.2 0.1 3.8 4 0 0 4 4 4 0 EB1-like C-terminal motif ADIP PF11559.8 EPS26880.1 - 6.9 6.7 52.3 2.4 8.2 6.9 3.9 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding RdRP PF05183.12 EPS26881.1 - 2.1e-187 624.4 0.0 3.2e-187 623.8 0.0 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase DNA_pol_B PF00136.21 EPS26882.1 - 4e-103 345.6 0.0 6.2e-103 345.0 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EPS26882.1 - 2.8e-22 79.3 0.7 3.3e-14 52.8 0.1 2.4 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EPS26882.1 - 5.8e-18 65.1 4.6 5.8e-18 65.1 4.6 2.5 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta Slu7 PF11708.8 EPS26883.1 - 1.2e-84 284.2 16.5 1.2e-84 284.2 16.5 1.7 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 EPS26883.1 - 0.029 14.1 0.6 0.071 12.8 0.6 1.6 1 0 0 1 1 1 0 Zinc knuckle Ribosomal_L37e PF01907.19 EPS26884.1 - 1.1e-28 99.1 12.3 1.6e-28 98.6 12.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 EPS26884.1 - 0.0028 17.7 1.7 0.0044 17.0 1.7 1.2 1 0 0 1 1 1 1 Double zinc ribbon CytoC_RC PF02276.18 EPS26884.1 - 0.016 14.6 0.1 0.017 14.5 0.1 1.1 1 0 0 1 1 1 0 Photosynthetic reaction centre cytochrome C subunit DUF35_N PF12172.8 EPS26884.1 - 0.07 13.0 2.4 0.13 12.2 2.4 1.4 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zinc_ribbon_2 PF13240.6 EPS26884.1 - 0.091 12.5 3.2 4 7.3 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain HypA PF01155.19 EPS26884.1 - 0.11 12.6 0.9 0.14 12.2 0.9 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-ribbon_3 PF13248.6 EPS26884.1 - 0.19 11.2 3.8 0.68 9.4 3.8 1.8 1 1 0 1 1 1 0 zinc-ribbon domain DUF2688 PF10892.8 EPS26884.1 - 1.2 8.7 6.0 2.7 7.5 2.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2688) ELP6 PF09807.9 EPS26885.1 - 9.1e-14 51.5 0.0 6.1e-07 29.1 0.0 2.2 2 0 0 2 2 2 2 Elongation complex protein 6 Elong_Iki1 PF10483.9 EPS26885.1 - 0.18 11.3 0.0 6.3 6.2 0.0 2.1 2 0 0 2 2 2 0 Elongator subunit Iki1 ATPase PF06745.13 EPS26885.1 - 0.2 11.0 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 KaiC Fungal_trans PF04082.18 EPS26886.1 - 1.6e-29 102.8 0.2 2.5e-29 102.2 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS26886.1 - 3.5e-10 39.8 10.5 6.6e-10 39.0 10.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 EPS26886.1 - 1.2e-05 25.3 0.1 2.5e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 Gal4-like dimerisation domain CIA30 PF08547.12 EPS26887.1 - 1.9e-44 151.5 0.1 2.5e-44 151.1 0.1 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) CBM_11 PF03425.13 EPS26887.1 - 0.0031 17.4 0.1 0.0041 17.0 0.1 1.4 1 1 0 1 1 1 1 Carbohydrate binding domain (family 11) TP_methylase PF00590.20 EPS26888.1 - 1e-50 172.7 0.1 1.8e-50 171.9 0.1 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.6 EPS26888.1 - 3.6e-15 56.3 0.0 6.5e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 EPS26888.1 - 2e-13 49.7 0.0 1.3e-09 37.5 0.0 2.4 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 EPS26888.1 - 1.6e-07 30.6 0.1 4.3e-07 29.3 0.1 1.8 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central PBP1_TM PF14812.6 EPS26888.1 - 0.044 14.2 0.2 0.11 12.9 0.2 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF498 PF04430.14 EPS26888.1 - 0.19 11.8 0.0 1.8 8.7 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF498/DUF598) PCI PF01399.27 EPS26889.1 - 3.4e-20 72.5 0.7 1.2e-19 70.8 0.0 2.2 2 0 0 2 2 2 1 PCI domain RPN5_C PF18098.1 EPS26889.1 - 2.1e-16 59.7 1.2 5e-16 58.5 1.2 1.7 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain ERp29 PF07749.12 EPS26889.1 - 4.2 8.3 6.0 4 8.4 0.1 3.2 3 0 0 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain FSH1 PF03959.13 EPS26890.1 - 8.3e-67 224.9 0.0 9.8e-67 224.7 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Ribosomal_S27e PF01667.17 EPS26892.1 - 1e-28 98.8 6.7 1.3e-28 98.5 6.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 zf-C2HC5 PF06221.13 EPS26892.1 - 0.69 9.9 6.4 2 8.4 4.2 2.3 2 1 0 2 2 2 0 Putative zinc finger motif, C2HC5-type CDP-OH_P_transf PF01066.21 EPS26894.1 - 5.1e-17 62.4 0.1 5.1e-17 62.4 0.1 3.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Prenyltrans PF00432.21 EPS26894.1 - 0.057 13.2 0.0 0.16 11.7 0.0 1.8 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat NIPSNAP PF07978.13 EPS26896.1 - 4.1e-43 145.8 0.6 1.5e-29 102.3 0.1 2.5 2 0 0 2 2 2 2 NIPSNAP MAS20 PF02064.15 EPS26896.1 - 0.05 13.7 1.1 0.096 12.8 1.1 1.4 1 0 0 1 1 1 0 MAS20 protein import receptor Putative_PNPOx PF01243.20 EPS26897.1 - 1.5e-12 47.5 0.1 5.2e-12 45.8 0.0 1.9 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 EPS26897.1 - 0.1 12.6 0.0 0.35 10.9 0.0 1.8 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase BPL_LplA_LipB PF03099.19 EPS26898.1 - 4.3e-07 29.9 0.0 9.5e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Ras PF00071.22 EPS26899.1 - 1.5e-50 171.0 0.0 1.7e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EPS26899.1 - 1.4e-19 70.5 0.0 2.4e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPS26899.1 - 1.4e-08 34.4 0.0 1.8e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EPS26899.1 - 0.0028 17.0 0.0 0.0037 16.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EPS26899.1 - 0.024 14.1 0.0 0.036 13.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EPS26899.1 - 0.074 12.9 0.0 1.8 8.5 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase G-alpha PF00503.20 EPS26899.1 - 0.1 11.8 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit PCI PF01399.27 EPS26900.1 - 3.7e-19 69.2 0.5 9.3e-19 67.9 0.1 2.0 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 EPS26900.1 - 0.0024 17.9 0.9 0.23 11.7 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EPS26900.1 - 0.023 14.5 0.8 0.46 10.4 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 EPS26900.1 - 0.038 14.0 0.8 1.2 9.3 0.0 3.5 4 1 0 4 4 4 0 Tetratricopeptide repeat KilA-N PF04383.13 EPS26900.1 - 0.062 13.2 0.7 0.21 11.5 0.2 2.1 2 0 0 2 2 2 0 KilA-N domain Pkinase_Tyr PF07714.17 EPS26900.1 - 0.068 12.4 0.1 9.4 5.4 0.0 2.2 2 0 0 2 2 2 0 Protein tyrosine kinase HTH_46 PF15977.5 EPS26900.1 - 0.1 12.6 0.1 13 5.8 0.0 2.7 2 0 0 2 2 2 0 Winged helix-turn-helix DNA binding TPR_11 PF13414.6 EPS26900.1 - 0.24 11.1 0.1 0.24 11.1 0.1 2.8 3 0 0 3 3 3 0 TPR repeat Peptidase_C65 PF10275.9 EPS26904.1 - 1.2e-57 195.2 0.0 1.6e-57 194.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain DeoC PF01791.9 EPS26908.1 - 4.1e-19 69.1 0.9 5.2e-19 68.8 0.9 1.1 1 0 0 1 1 1 1 DeoC/LacD family aldolase DHO_dh PF01180.21 EPS26908.1 - 0.0016 17.7 0.2 0.0036 16.5 0.1 1.5 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 EPS26908.1 - 0.014 14.4 0.4 0.04 12.9 0.4 1.7 1 1 0 1 1 1 0 FMN-dependent dehydrogenase SelK_SelG PF10961.8 EPS26909.1 - 1.8e-06 28.4 10.3 1.2e-05 25.9 10.3 1.9 1 1 0 1 1 1 1 Selenoprotein SelK_SelG Sugar_tr PF00083.24 EPS26910.1 - 6.8e-121 404.3 15.2 1.1e-120 403.5 15.2 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS26910.1 - 3.9e-22 78.6 44.2 1.6e-13 50.3 16.3 2.5 1 1 0 2 2 2 2 Major Facilitator Superfamily DJ-1_PfpI PF01965.24 EPS26911.1 - 1.2e-10 41.4 0.0 1.6e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 EPS26911.1 - 0.13 12.0 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Asp PF00026.23 EPS26912.1 - 7.6e-57 193.1 1.2 1e-56 192.7 1.2 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EPS26912.1 - 2.1e-07 31.4 1.2 0.00027 21.2 1.2 3.0 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EPS26912.1 - 0.00036 20.3 0.0 0.0007 19.4 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.6 EPS26912.1 - 0.027 15.1 3.8 9.7 6.9 0.0 3.7 4 0 0 4 4 4 0 Aspartyl protease Sugar_tr PF00083.24 EPS26913.1 - 4.3e-81 273.1 22.1 5.2e-81 272.8 22.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS26913.1 - 6e-11 41.9 40.9 2.2e-07 30.1 19.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EPS26913.1 - 0.0055 15.6 5.0 0.0055 15.6 5.0 2.4 3 0 0 3 3 3 1 MFS_1 like family TPR_8 PF13181.6 EPS26913.1 - 0.16 12.3 0.0 0.98 9.8 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Abhydrolase_3 PF07859.13 EPS26914.1 - 6.3e-16 58.9 0.0 9e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EPS26914.1 - 2.8e-06 26.8 0.1 3.2e-05 23.3 0.1 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EPS26914.1 - 5.7e-06 26.0 0.0 0.0048 16.4 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 EPS26914.1 - 5.5e-05 22.2 0.0 7.2e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme AXE1 PF05448.12 EPS26914.1 - 0.00012 20.9 0.0 0.095 11.4 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.9 EPS26914.1 - 0.0002 20.9 1.1 0.015 14.8 0.3 2.7 2 1 0 2 2 2 1 Esterase PHB depolymerase Esterase PF00756.20 EPS26914.1 - 0.001 18.7 0.0 0.0017 18.0 0.0 1.4 1 0 0 1 1 1 1 Putative esterase COesterase PF00135.28 EPS26914.1 - 0.0034 16.3 0.0 0.023 13.6 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_2 PF02230.16 EPS26914.1 - 0.0041 17.0 0.0 0.099 12.4 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 EPS26914.1 - 0.021 14.5 0.0 0.097 12.3 0.0 2.1 2 1 0 2 2 2 0 alpha/beta hydrolase fold Chlorophyllase PF07224.11 EPS26914.1 - 0.024 13.7 0.0 0.032 13.2 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase TMEM234 PF10639.9 EPS26915.1 - 8.7e-33 112.8 0.5 6.3e-25 87.5 0.2 2.1 2 0 0 2 2 2 2 Putative transmembrane family 234 EamA PF00892.20 EPS26915.1 - 0.0074 16.5 6.5 0.72 10.0 4.2 2.2 2 0 0 2 2 2 2 EamA-like transporter family Chitin_synth_1 PF01644.17 EPS26916.1 - 2.3e-75 252.1 0.0 3.7e-75 251.4 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EPS26916.1 - 1e-28 99.1 0.0 1.9e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EPS26916.1 - 6.1e-22 77.9 1.7 3.9e-18 65.4 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase LMWPc PF01451.21 EPS26918.1 - 7.7e-34 117.1 0.0 2.3e-32 112.3 0.0 2.0 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase DUF2694 PF10904.8 EPS26918.1 - 0.046 13.8 0.0 0.083 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2694) COQ7 PF03232.13 EPS26919.1 - 1.1e-67 227.1 1.5 1.4e-67 226.8 1.5 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 EPS26919.1 - 1.9e-06 28.3 2.4 1.3e-05 25.6 0.1 2.2 1 1 1 2 2 2 1 Rubrerythrin SopA_C PF13979.6 EPS26919.1 - 0.038 13.7 0.1 0.06 13.1 0.1 1.2 1 0 0 1 1 1 0 SopA-like catalytic domain Plus-3 PF03126.18 EPS26920.1 - 1.3e-33 115.7 0.0 5.5e-33 113.8 0.0 2.1 2 0 0 2 2 2 1 Plus-3 domain MRC1 PF09444.10 EPS26921.1 - 2.7e-41 141.5 23.4 2.7e-41 141.5 23.4 7.3 6 1 1 7 7 7 2 MRC1-like domain KR PF08659.10 EPS26921.1 - 0.12 12.3 0.8 0.29 11.0 0.8 1.6 1 0 0 1 1 1 0 KR domain Hydrolase_like PF13242.6 EPS26922.1 - 2.4e-06 27.5 0.0 5e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like FAD_binding_3 PF01494.19 EPS26924.1 - 7.5e-19 68.2 0.1 1.5e-17 63.9 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EPS26924.1 - 9.1e-08 32.2 0.5 2.3e-07 30.9 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EPS26924.1 - 4.1e-06 26.6 1.4 8.5e-05 22.3 0.5 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EPS26924.1 - 0.00048 19.3 2.2 0.0012 18.0 1.5 1.8 1 1 1 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EPS26924.1 - 0.0038 16.5 0.7 0.007 15.6 0.3 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 EPS26924.1 - 0.041 13.5 1.1 0.1 12.2 0.3 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.17 EPS26924.1 - 0.043 13.1 0.4 0.072 12.3 0.4 1.5 1 1 0 1 1 1 0 Thi4 family GIDA PF01134.22 EPS26924.1 - 0.066 12.3 0.7 0.11 11.6 0.7 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 EPS26924.1 - 0.18 10.6 0.5 0.29 9.9 0.5 1.3 1 0 0 1 1 1 0 Tryptophan halogenase ThiF PF00899.21 EPS26924.1 - 0.2 11.0 0.5 0.43 9.9 0.1 1.7 2 0 0 2 2 2 0 ThiF family TBCC PF07986.12 EPS26925.1 - 9.7e-33 112.4 1.3 1.5e-32 111.9 1.3 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 EPS26925.1 - 4e-07 30.5 0.3 7e-07 29.7 0.3 1.3 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain Halo_GVPC PF05465.13 EPS26925.1 - 0.12 12.6 0.9 0.2 11.9 0.1 1.7 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat Pro-kuma_activ PF09286.11 EPS26926.1 - 1.2e-34 119.6 0.0 2.1e-34 118.8 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain CSN8_PSD8_EIF3K PF10075.9 EPS26927.1 - 5.5e-19 68.6 0.0 9.6e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family CDC37_C PF08564.10 EPS26927.1 - 0.11 12.6 0.1 0.73 10.0 0.1 2.2 3 0 0 3 3 3 0 Cdc37 C terminal domain DUF1917 PF08939.10 EPS26929.1 - 9.8e-89 297.7 0.0 1.1e-88 297.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) TrmB PF01978.19 EPS26929.1 - 0.054 13.4 0.8 0.11 12.4 0.1 1.8 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Vps51 PF08700.11 EPS26930.1 - 9.1e-27 93.0 0.0 1.4e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.9 EPS26930.1 - 0.032 14.4 0.0 0.055 13.6 0.0 1.3 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Dor1 PF04124.12 EPS26930.1 - 0.069 11.8 0.0 0.082 11.6 0.0 1.2 1 0 0 1 1 1 0 Dor1-like family RMI1_N PF08585.12 EPS26931.1 - 1.7e-60 204.5 0.0 2e-60 204.3 0.0 1.0 1 0 0 1 1 1 1 RecQ mediated genome instability protein Shikimate_DH PF01488.20 EPS26931.1 - 0.15 12.1 0.1 0.24 11.5 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TPR_2 PF07719.17 EPS26932.1 - 3.2e-22 76.8 51.5 0.0086 16.1 0.0 16.2 18 0 0 18 18 18 6 Tetratricopeptide repeat TPR_16 PF13432.6 EPS26932.1 - 1.7e-20 73.3 49.9 3.4e-05 24.4 4.8 12.2 11 2 2 13 13 12 7 Tetratricopeptide repeat TPR_1 PF00515.28 EPS26932.1 - 9.6e-20 69.5 39.5 0.0013 18.4 0.1 14.8 17 0 0 17 17 17 6 Tetratricopeptide repeat TPR_17 PF13431.6 EPS26932.1 - 6.2e-18 63.8 26.5 0.53 10.8 0.0 14.4 18 0 0 18 18 17 6 Tetratricopeptide repeat TPR_19 PF14559.6 EPS26932.1 - 4.8e-17 62.2 32.2 0.0074 16.8 0.3 11.5 10 3 2 12 12 12 6 Tetratricopeptide repeat TPR_8 PF13181.6 EPS26932.1 - 1.6e-16 59.1 35.9 0.097 12.9 0.0 14.9 16 1 1 17 17 17 7 Tetratricopeptide repeat TPR_14 PF13428.6 EPS26932.1 - 1.8e-16 59.4 44.2 0.0005 20.7 0.0 16.6 14 6 5 19 19 18 4 Tetratricopeptide repeat TPR_11 PF13414.6 EPS26932.1 - 8.8e-12 44.5 20.3 0.12 12.1 0.0 10.9 11 0 0 11 11 11 3 TPR repeat TPR_12 PF13424.6 EPS26932.1 - 6.6e-11 42.4 43.3 7.8e-07 29.3 0.5 11.5 10 2 2 12 12 12 4 Tetratricopeptide repeat TPR_7 PF13176.6 EPS26932.1 - 8.7e-07 28.5 14.2 0.025 14.6 0.0 8.8 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_6 PF13174.6 EPS26932.1 - 1.3e-06 28.7 33.7 0.0037 17.8 0.0 11.8 13 0 0 13 13 12 2 Tetratricopeptide repeat TPR_9 PF13371.6 EPS26932.1 - 8.2e-06 25.9 10.9 0.37 11.0 0.0 6.7 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_22 PF18833.1 EPS26932.1 - 6.1e-05 23.1 0.0 0.00018 21.6 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EPS26932.1 - 0.16 12.2 12.7 1.1 9.6 0.2 6.2 6 1 1 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 EPS26932.1 - 0.33 11.0 3.7 22 5.2 0.1 4.0 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat Glyco_hydro_5_C PF18564.1 EPS26933.1 - 9.5e-22 77.3 0.1 2.3e-21 76.1 0.1 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Cellulase PF00150.18 EPS26933.1 - 1.8e-08 34.2 4.8 8.1e-07 28.7 2.6 2.8 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Xpo1 PF08389.12 EPS26934.1 - 3.1e-09 37.0 4.4 3.5e-06 27.1 1.5 4.4 3 1 0 3 3 3 1 Exportin 1-like protein HEAT_2 PF13646.6 EPS26934.1 - 0.32 11.4 4.5 0.67 10.4 0.1 3.8 4 1 1 5 5 5 0 HEAT repeats GRIM-19 PF06212.12 EPS26935.1 - 1.1e-23 83.7 1.4 4.1e-23 81.8 1.4 1.7 1 1 0 1 1 1 1 GRIM-19 protein tRNA_m1G_MT PF01746.21 EPS26936.1 - 8.5e-26 90.9 0.0 4.1e-25 88.6 0.0 1.9 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Presenilin PF01080.17 EPS26936.1 - 0.59 8.8 1.3 0.76 8.5 1.3 1.3 1 0 0 1 1 1 0 Presenilin VID27 PF08553.10 EPS26937.1 - 6.5e-196 650.4 0.0 9.1e-196 649.9 0.0 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 EPS26937.1 - 7.3e-76 253.8 0.5 7.3e-76 253.8 0.5 2.7 2 1 0 2 2 2 1 VID27 N-terminal region VID27_PH PF17747.1 EPS26937.1 - 3.1e-47 159.4 1.8 1.1e-46 157.6 1.0 2.1 2 0 0 2 2 2 1 VID27 PH-like domain UPF0149 PF03695.13 EPS26937.1 - 0.0058 16.9 5.5 0.092 13.0 4.4 2.3 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0149) Nop14 PF04147.12 EPS26937.1 - 0.15 10.3 16.6 0.28 9.4 16.6 1.4 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EPS26937.1 - 1.2 7.3 13.1 2.3 6.4 13.1 1.4 1 0 0 1 1 1 0 CDC45-like protein zf-Di19 PF05605.12 EPS26938.1 - 0.092 13.1 11.5 0.9 9.9 0.3 5.3 5 0 0 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding DUF3734 PF12536.8 EPS26941.1 - 0.045 14.1 3.6 0.53 10.6 0.9 2.8 1 1 2 3 3 3 0 Patatin phospholipase RTA1 PF04479.13 EPS26943.1 - 1.4e-66 224.0 13.6 1.4e-66 224.0 13.6 1.6 1 1 1 2 2 2 1 RTA1 like protein DUF996 PF06195.13 EPS26944.1 - 0.053 13.8 0.6 0.053 13.8 0.6 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF996) Rod_cone_degen PF15201.6 EPS26944.1 - 0.18 11.9 0.1 0.48 10.6 0.1 1.7 1 0 0 1 1 1 0 Progressive rod-cone degeneration DUF2070 PF09843.9 EPS26944.1 - 0.38 9.0 14.9 0.31 9.3 1.3 2.2 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) DUF4965 PF16335.5 EPS26945.1 - 5.5e-06 26.1 0.0 8.3e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) HNH_2 PF13391.6 EPS26945.1 - 9.3e-05 22.5 0.0 0.00019 21.5 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease TLD PF07534.16 EPS26947.1 - 3.4e-25 88.9 0.0 6.6e-16 58.8 0.0 2.2 2 0 0 2 2 2 2 TLD Spherulin4 PF12138.8 EPS26948.1 - 4.2e-34 118.2 0.2 6.9e-34 117.6 0.2 1.3 1 0 0 1 1 1 1 Spherulation-specific family 4 MU117 PF15474.6 EPS26948.1 - 6.9e-19 68.5 8.6 1.8e-18 67.2 8.6 1.8 1 0 0 1 1 1 1 Meiotically up-regulated gene family Lipase_GDSL_2 PF13472.6 EPS26948.1 - 3.9e-07 30.6 1.1 1.5e-06 28.7 1.1 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family fn3 PF00041.21 EPS26948.1 - 0.0034 17.7 0.0 0.0086 16.4 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain Bacteriocin_IIc PF10439.9 EPS26948.1 - 0.0037 17.4 0.9 0.013 15.6 0.9 2.0 1 0 0 1 1 1 1 Bacteriocin class II with double-glycine leader peptide Kp4 PF09044.10 EPS26948.1 - 0.076 13.1 6.7 0.076 13.1 5.0 1.8 2 0 0 2 2 2 0 Kp4 F-box-like PF12937.7 EPS26950.1 - 0.00013 21.8 0.2 0.00025 20.9 0.2 1.5 1 0 0 1 1 1 1 F-box-like FNIP PF05725.12 EPS26950.1 - 0.037 14.2 1.1 10 6.4 0.0 3.5 4 0 0 4 4 4 0 FNIP Repeat F-box PF00646.33 EPS26950.1 - 0.091 12.7 2.5 0.15 12.0 0.1 2.5 3 0 0 3 3 3 0 F-box domain JAB PF01398.21 EPS26952.1 - 1.3e-13 50.9 0.0 3e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.11 EPS26952.1 - 3.8e-10 40.0 1.3 8e-10 38.9 1.3 1.5 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.6 EPS26952.1 - 5.3e-05 23.0 0.0 0.00016 21.4 0.0 1.8 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain TarH PF02203.15 EPS26952.1 - 0.47 10.4 2.4 0.53 10.2 0.5 1.9 1 1 1 2 2 2 0 Tar ligand binding domain homologue Tropomyosin_1 PF12718.7 EPS26953.1 - 0.12 12.5 0.1 0.23 11.6 0.1 1.4 1 0 0 1 1 1 0 Tropomyosin like ATP-synt_DE PF00401.20 EPS26953.1 - 0.72 10.2 2.9 1.9 8.8 2.9 1.7 1 0 0 1 1 1 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Pkinase PF00069.25 EPS26954.1 - 2.2e-12 46.9 0.0 3e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS26954.1 - 0.0015 17.9 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EPS26954.1 - 0.0017 17.2 0.0 0.0025 16.6 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EPS26954.1 - 0.0087 16.0 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EPS26954.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Polyketide_cyc2 PF10604.9 EPS26955.1 - 6.3e-07 29.8 5.3 1.8e-06 28.2 5.1 1.9 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 EPS26955.1 - 0.00013 22.2 0.4 0.0005 20.3 0.4 2.0 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport CRISPR_assoc PF08798.11 EPS26955.1 - 0.00016 21.9 0.0 0.00019 21.6 0.0 1.2 1 0 0 1 1 1 1 CRISPR associated protein Glyco_hydro_28 PF00295.17 EPS26956.1 - 3e-44 151.4 12.8 1.9e-42 145.5 7.9 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 28 Amidase PF01425.21 EPS26957.1 - 6.1e-97 325.4 0.0 2.2e-96 323.6 0.0 1.7 1 1 0 1 1 1 1 Amidase DUF1304 PF06993.12 EPS26958.1 - 0.43 10.6 5.8 0.1 12.6 1.4 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1304) Iso_dh PF00180.20 EPS26959.1 - 2.8e-72 243.8 0.0 3.3e-72 243.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase FTHFS PF01268.19 EPS26961.1 - 3.8e-252 837.4 0.1 6.1e-252 836.8 0.0 1.4 2 0 0 2 2 2 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 EPS26961.1 - 8.7e-67 223.4 1.3 1.9e-66 222.3 1.3 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 EPS26961.1 - 1e-38 132.1 0.3 2.2e-38 131.1 0.3 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 EPS26961.1 - 0.0024 16.9 0.3 0.0048 15.9 0.3 1.4 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family WD40 PF00400.32 EPS26962.1 - 3.8e-30 103.5 1.3 1.9e-08 34.8 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS26962.1 - 2.3e-12 47.0 0.0 0.0021 18.3 0.1 5.8 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EPS26962.1 - 0.00019 21.1 0.4 0.00087 18.9 0.3 2.0 1 1 0 1 1 1 1 PQQ-like domain Nup160 PF11715.8 EPS26962.1 - 0.00066 18.5 0.2 0.0009 18.0 0.2 1.3 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Gmad1 PF10647.9 EPS26962.1 - 0.0097 15.7 0.1 0.11 12.2 0.2 2.0 1 1 1 2 2 2 1 Lipoprotein LpqB beta-propeller domain WD40_like PF17005.5 EPS26962.1 - 0.04 13.3 0.0 1.3 8.3 0.0 2.9 3 1 1 4 4 4 0 WD40-like domain MBF1 PF08523.10 EPS26963.1 - 2.9e-26 91.7 0.6 6.3e-26 90.6 0.6 1.6 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 EPS26963.1 - 2.7e-10 40.2 0.1 4.6e-10 39.4 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EPS26963.1 - 6.5e-05 23.2 0.0 0.00014 22.1 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain Glyoxalase_6 PF18029.1 EPS26964.1 - 5.6e-07 30.3 0.1 8e-07 29.8 0.1 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.25 EPS26964.1 - 0.0015 18.7 0.0 0.0044 17.2 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SH3_9 PF14604.6 EPS26965.1 - 1.3e-14 53.7 0.0 2.2e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EPS26965.1 - 1.6e-14 53.3 0.1 2.4e-14 52.6 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EPS26965.1 - 6.4e-09 35.4 0.0 1e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain CBP_BcsO PF17037.5 EPS26965.1 - 1.1 9.4 10.5 0.28 11.3 7.4 1.7 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsO Ank_2 PF12796.7 EPS26966.1 - 2.1e-27 95.5 3.6 4.2e-12 46.5 0.1 3.8 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPS26966.1 - 1.2e-23 83.2 2.1 2.4e-08 34.4 0.0 5.2 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPS26966.1 - 2.1e-20 70.6 0.0 0.0018 18.6 0.0 7.2 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.6 EPS26966.1 - 5.9e-19 67.9 1.8 7.1e-06 26.2 0.1 4.6 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 EPS26966.1 - 2e-17 62.7 2.1 0.0037 17.6 0.0 6.9 8 0 0 8 8 8 3 Ankyrin repeat AIM24 PF01987.17 EPS26967.1 - 5.4e-54 183.1 0.1 6.7e-54 182.7 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 TFIIA PF03153.13 EPS26967.1 - 6.7 6.6 13.5 8.9 6.2 13.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF-5_eIF-2B PF01873.17 EPS26968.1 - 3.8e-40 136.4 0.2 6.6e-40 135.6 0.2 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 zinc_ribbon_6 PF14599.6 EPS26968.1 - 0.043 13.8 0.3 6.5 6.8 0.1 2.6 2 0 0 2 2 2 0 Zinc-ribbon TF_Zn_Ribbon PF08271.12 EPS26968.1 - 0.1 12.1 1.1 0.23 11.0 1.1 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding GET2 PF08690.10 EPS26968.1 - 1.2 8.8 4.6 1.7 8.3 4.6 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Arc_trans_TRASH PF08394.10 EPS26968.1 - 1.5 9.2 7.3 1.7 9.0 0.3 2.7 1 1 1 2 2 2 0 Archaeal TRASH domain TFIIA PF03153.13 EPS26968.1 - 3 7.7 10.2 4.2 7.3 10.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF5406 PF17400.2 EPS26969.1 - 0.05 14.0 0.6 10 6.6 0.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5406) RRM_1 PF00076.22 EPS26971.1 - 3.9e-21 74.7 0.0 5.1e-21 74.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EPS26971.1 - 0.033 14.3 0.0 0.049 13.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif ChaC PF04752.12 EPS26972.1 - 8.7e-54 182.3 0.0 1.1e-53 182.0 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein MFS_1 PF07690.16 EPS26973.1 - 6.5e-50 170.0 64.7 4.8e-49 167.2 63.6 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EPS26973.1 - 4.2e-23 81.6 19.5 4.2e-23 81.6 19.5 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EPS26973.1 - 4.8e-17 62.0 4.7 4.8e-17 62.0 4.7 3.4 3 1 0 3 3 3 2 Sugar (and other) transporter EF-hand_1 PF00036.32 EPS26974.1 - 1.2e-21 74.6 6.9 4.3e-08 32.2 0.4 4.7 4 1 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EPS26974.1 - 1.7e-20 71.2 3.3 9.1e-06 25.2 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 EPS26974.1 - 9e-19 67.7 3.0 1.9e-08 34.6 0.0 3.3 2 1 0 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 EPS26974.1 - 1.6e-18 66.2 4.2 3.9e-09 36.2 0.0 3.8 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 EPS26974.1 - 7.3e-13 47.4 7.5 0.00014 21.2 0.4 3.8 3 1 0 3 3 3 3 EF hand DUF4121 PF13497.6 EPS26974.1 - 0.11 11.6 0.1 7.2 5.7 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4121) EF-hand_14 PF17959.1 EPS26974.1 - 0.17 12.3 0.0 0.42 11.0 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain adh_short PF00106.25 EPS26975.1 - 3.3e-20 72.4 0.0 1.7e-17 63.5 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EPS26975.1 - 1.1e-12 48.0 0.0 6e-09 35.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPS26975.1 - 5.4e-07 29.7 0.0 7.7e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 KR domain OPT PF03169.15 EPS26976.1 - 3.8e-122 409.0 38.1 4.4e-122 408.8 38.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein GrpE PF01025.19 EPS26976.1 - 0.28 10.8 0.0 0.7 9.5 0.0 1.5 2 0 0 2 2 2 0 GrpE Aminotran_1_2 PF00155.21 EPS26977.1 - 1.9e-42 145.8 0.0 2.3e-42 145.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II GFA PF04828.14 EPS26978.1 - 3.1e-24 85.1 0.1 3.1e-24 85.1 0.1 1.4 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme SRF-TF PF00319.18 EPS26979.1 - 1.6e-23 81.9 0.2 2.4e-23 81.4 0.2 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF1708 PF08101.11 EPS26981.1 - 7.2e-178 592.2 0.0 1.1e-177 591.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) DJ-1_PfpI PF01965.24 EPS26982.1 - 1.1e-09 38.3 0.0 2.1e-09 37.4 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EPS26982.1 - 1.1e-05 25.2 0.0 4e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 ThiJ/PfpI family-like MFS_2 PF13347.6 EPS26983.1 - 2.4e-10 39.5 8.9 2.4e-10 39.5 8.9 2.3 2 1 0 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.7 EPS26983.1 - 7.7e-05 21.7 0.0 0.00021 20.3 0.0 1.8 1 1 0 1 1 1 1 MFS_1 like family BT1 PF03092.16 EPS26983.1 - 0.067 11.4 3.8 0.13 10.5 3.8 1.4 1 0 0 1 1 1 0 BT1 family G6PD_C PF02781.16 EPS26984.1 - 3e-116 387.7 0.0 5.5e-116 386.8 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 EPS26984.1 - 3.8e-62 210.0 0.1 6.5e-62 209.3 0.1 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF3226 PF11536.8 EPS26984.1 - 0.095 12.4 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3226) Ribosomal_L35Ae PF01247.18 EPS26985.1 - 4.4e-44 148.6 0.3 4.9e-44 148.4 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 EPS26985.1 - 0.00085 19.5 0.0 0.77 10.0 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain DUF2080 PF09853.9 EPS26985.1 - 0.089 12.6 1.5 0.47 10.2 0.2 2.2 1 1 1 2 2 2 0 Putative transposon-encoded protein (DUF2080) DUF2406 PF10295.9 EPS26987.1 - 4e-25 88.3 1.9 6.6e-25 87.6 0.0 2.4 2 1 0 2 2 2 1 Uncharacterised protein (DUF2406) DUF3602 PF12223.8 EPS26988.1 - 1.1e-25 90.0 15.0 2.9e-22 79.1 4.9 2.8 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Mito_carr PF00153.27 EPS26989.1 - 2.9e-46 155.3 7.1 1.3e-17 63.5 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CBS PF00571.28 EPS26990.1 - 9e-08 32.4 0.0 0.052 14.0 0.0 3.1 1 1 2 3 3 3 3 CBS domain Elong_Iki1 PF10483.9 EPS26990.1 - 0.096 12.2 0.0 0.12 11.8 0.0 1.1 1 0 0 1 1 1 0 Elongator subunit Iki1 VMA21 PF09446.10 EPS26991.1 - 6.8e-15 54.9 9.0 9.6e-15 54.4 9.0 1.2 1 0 0 1 1 1 1 VMA21-like domain SNF2_N PF00176.23 EPS26992.1 - 6.5e-52 176.4 0.1 1.2e-51 175.5 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EPS26992.1 - 5.3e-18 65.4 0.2 5.7e-17 62.1 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPS26992.1 - 1.8e-10 41.1 0.0 4e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EPS26992.1 - 5.3e-05 23.1 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 EPS26992.1 - 0.00016 21.0 0.1 0.00032 20.0 0.1 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase HIGH_NTase1_ass PF16581.5 EPS26992.1 - 0.026 14.5 0.1 0.098 12.6 0.0 1.9 2 0 0 2 2 2 0 Cytidyltransferase-related C-terminal region UBA PF00627.31 EPS26992.1 - 0.07 13.1 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 UBA/TS-N domain Dus PF01207.17 EPS26993.1 - 1.6e-42 145.7 0.0 5.5e-42 144.0 0.0 1.8 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Pyrophosphatase PF00719.19 EPS26994.1 - 7.5e-60 201.4 0.2 9.3e-60 201.1 0.2 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Sec20 PF03908.13 EPS26996.1 - 7.2e-15 54.7 1.0 1.8e-14 53.4 1.0 1.7 1 0 0 1 1 1 1 Sec20 Amidase_3 PF01520.18 EPS26996.1 - 0.018 15.2 1.1 0.4 10.8 0.1 2.3 1 1 1 2 2 2 0 N-acetylmuramoyl-L-alanine amidase MutS_II PF05188.17 EPS26996.1 - 0.37 11.1 4.1 0.91 9.8 4.1 1.6 1 0 0 1 1 1 0 MutS domain II US30 PF17624.2 EPS26996.1 - 0.5 9.4 3.3 0.78 8.7 3.3 1.3 1 0 0 1 1 1 0 Family of unknown function Rep_fac_C PF08542.11 EPS26997.1 - 5.2e-20 71.7 0.0 9.7e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 EPS26997.1 - 3.2e-15 56.7 0.0 9.7e-15 55.2 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EPS26997.1 - 4.9e-13 49.2 0.0 5e-08 32.9 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 EPS26997.1 - 1.4e-09 38.1 0.0 3.6e-09 36.8 0.0 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 EPS26997.1 - 9.8e-06 25.4 0.0 5e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EPS26997.1 - 3.4e-05 24.3 0.1 0.001 19.5 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_assoc_2 PF16193.5 EPS26997.1 - 8.6e-05 22.8 0.0 0.00028 21.2 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain AAA_11 PF13086.6 EPS26997.1 - 9.1e-05 22.4 0.1 0.00028 20.8 0.0 1.8 1 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EPS26997.1 - 0.00011 21.6 0.0 0.0097 15.3 0.0 2.5 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 EPS26997.1 - 0.00014 22.2 0.0 0.0005 20.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EPS26997.1 - 0.0014 18.3 0.0 0.0052 16.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EPS26997.1 - 0.003 17.6 0.0 0.0068 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EPS26997.1 - 0.004 16.5 0.0 0.0071 15.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 EPS26997.1 - 0.0066 16.8 0.0 0.057 13.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EPS26997.1 - 0.0069 16.4 0.1 0.046 13.7 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DNA_pol3_delta PF06144.13 EPS26997.1 - 0.0082 15.9 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit DUF815 PF05673.13 EPS26997.1 - 0.013 14.6 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 EPS26997.1 - 0.015 14.9 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 EPS26997.1 - 0.034 13.9 0.2 0.19 11.5 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EPS26997.1 - 0.045 14.3 0.0 0.18 12.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 EPS26997.1 - 0.047 13.5 0.0 0.33 10.7 0.0 2.1 2 0 0 2 2 2 0 DEAD/DEAH box helicase ResIII PF04851.15 EPS26997.1 - 0.052 13.5 0.0 0.33 10.9 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit MCM PF00493.23 EPS26997.1 - 0.076 12.1 0.0 2.9 6.9 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain AAA_28 PF13521.6 EPS26997.1 - 0.083 13.1 0.0 0.21 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EPS26997.1 - 0.1 13.1 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 EPS26997.1 - 0.15 11.9 0.0 2.9 7.7 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CdiI_3 PF18616.1 EPS26997.1 - 0.17 11.8 0.1 0.46 10.4 0.1 1.7 1 0 0 1 1 1 0 CDI immunity proteins CsiV PF10972.8 EPS26998.1 - 0.043 13.5 0.1 0.043 13.5 0.1 1.1 1 0 0 1 1 1 0 Peptidoglycan-binding protein, CsiV RRG8 PF17068.5 EPS26999.1 - 0.015 14.7 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Required for respiratory growth protein 8 mitochondrial CLP_protease PF00574.23 EPS27000.1 - 1.6e-76 256.3 0.0 1.9e-76 256.0 0.0 1.1 1 0 0 1 1 1 1 Clp protease Tugs PF17840.1 EPS27000.1 - 0.031 14.5 1.4 0.064 13.5 1.4 1.5 1 0 0 1 1 1 0 Tethering Ubl4a to BAGS domain Peptidase_S49 PF01343.18 EPS27000.1 - 0.15 12.1 0.1 0.38 10.7 0.1 1.6 1 1 0 1 1 1 0 Peptidase family S49 DUF1746 PF08508.10 EPS27001.1 - 1.9e-37 128.2 2.5 2.5e-37 127.7 2.5 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) Peptidase_M18 PF02127.15 EPS27002.1 - 5.1e-170 565.9 0.0 5.8e-170 565.7 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) WD40 PF00400.32 EPS27004.1 - 7.4e-26 89.9 11.1 6.5e-05 23.6 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS27004.1 - 5.7e-13 49.0 8.1 0.00016 21.9 0.5 4.3 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EPS27004.1 - 7.4e-09 35.8 0.4 0.0027 17.6 0.0 3.2 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EPS27004.1 - 0.023 13.6 0.0 0.13 11.2 0.0 2.1 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein E3_binding PF02817.17 EPS27005.1 - 8.7e-09 35.6 0.4 3.7e-08 33.6 0.0 2.2 2 0 0 2 2 2 1 e3 binding domain DUF5585 PF17823.1 EPS27005.1 - 0.22 10.5 6.9 0.12 11.3 4.3 1.6 1 1 0 2 2 2 0 Family of unknown function (DUF5585) MreD PF04093.12 EPS27006.1 - 0.0035 17.4 0.4 0.0053 16.8 0.4 1.2 1 0 0 1 1 1 1 rod shape-determining protein MreD SMC_N PF02463.19 EPS27007.1 - 4.3e-55 186.5 13.3 4.4e-54 183.2 13.3 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EPS27007.1 - 5e-30 104.2 0.0 1.7e-29 102.5 0.0 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 EPS27007.1 - 4.9e-09 36.4 19.0 4.4e-05 23.4 0.1 4.4 3 2 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EPS27007.1 - 6.7e-08 32.2 0.0 1.5e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 EPS27007.1 - 3.8e-07 30.1 6.2 3.8e-07 30.1 6.2 4.5 3 1 1 4 4 3 1 AAA ATPase domain AAA_23 PF13476.6 EPS27007.1 - 0.0013 19.2 41.5 0.0013 19.2 41.5 6.9 3 2 2 5 5 3 1 AAA domain ATG16 PF08614.11 EPS27007.1 - 0.0029 17.9 8.8 0.0029 17.9 8.8 6.6 4 2 3 7 7 7 1 Autophagy protein 16 (ATG16) zf-C4H2 PF10146.9 EPS27007.1 - 0.0036 17.6 17.5 0.0036 17.6 17.5 6.7 3 2 2 6 6 4 1 Zinc finger-containing protein SbcCD_C PF13558.6 EPS27007.1 - 0.0048 17.1 0.0 0.025 14.8 0.0 2.3 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit CENP-K PF11802.8 EPS27007.1 - 0.0049 16.5 0.9 0.0049 16.5 0.9 4.7 2 2 1 4 4 3 1 Centromere-associated protein K ABC_tran PF00005.27 EPS27007.1 - 1.2 9.6 0.0 1.2 9.6 0.0 6.7 4 2 2 6 6 5 0 ABC transporter TMP_2 PF06791.13 EPS27007.1 - 4.9 6.8 6.0 0.75 9.4 0.2 2.7 3 0 0 3 3 3 0 Prophage tail length tape measure protein AAA_22 PF13401.6 EPS27007.1 - 4.9 7.4 9.2 11 6.3 0.0 5.0 5 1 0 5 5 5 0 AAA domain Glyco_hydro_79C PF16862.5 EPS27008.1 - 6.7e-24 84.8 0.1 1.3e-23 83.8 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain DUF2841 PF11001.8 EPS27010.1 - 1.1e-47 161.1 0.1 1.7e-47 160.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) X PF00739.19 EPS27010.1 - 0.011 15.9 0.9 0.023 14.8 0.9 1.5 1 0 0 1 1 1 0 Trans-activation protein X Zn_clus PF00172.18 EPS27011.1 - 2.4e-06 27.6 17.1 4.7e-06 26.6 17.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CN_hydrolase PF00795.22 EPS27012.1 - 5.4e-42 143.9 0.2 6.6e-42 143.6 0.2 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF2838 PF10998.8 EPS27013.1 - 8.8e-43 145.1 12.9 8.8e-43 145.1 12.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) Atg14 PF10186.9 EPS27013.1 - 0.37 9.8 1.0 0.58 9.2 1.0 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 LETM1 PF07766.13 EPS27014.1 - 1.9e-104 348.8 0.1 3.1e-104 348.1 0.1 1.3 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.27 EPS27014.1 - 3.5e-05 23.4 0.0 0.0039 16.9 0.0 2.7 2 0 0 2 2 2 2 SAP domain NUDIX PF00293.28 EPS27015.1 - 0.0016 18.5 0.2 0.0048 17.0 0.1 1.9 1 1 0 1 1 1 1 NUDIX domain BUD22 PF09073.10 EPS27016.1 - 1.2 8.4 9.9 2.5 7.4 9.9 1.5 1 0 0 1 1 1 0 BUD22 CENP-B_dimeris PF09026.10 EPS27016.1 - 5.8 7.4 14.1 4 7.9 4.2 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain FAM176 PF14851.6 EPS27016.1 - 9.4 5.9 9.3 16 5.1 0.8 2.3 2 0 0 2 2 2 0 FAM176 family Gpr1_Fun34_YaaH PF01184.19 EPS27017.1 - 3.9e-57 193.2 14.7 4.9e-57 192.9 14.7 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Glyco_hydro_38N PF01074.22 EPS27018.1 - 4.6e-85 285.5 1.7 4.6e-85 285.5 1.7 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 EPS27018.1 - 4.5e-52 177.2 0.0 3.2e-51 174.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 EPS27018.1 - 2.8e-27 94.7 0.0 5.8e-27 93.7 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 EPS27018.1 - 1.5e-12 47.5 0.0 4.6e-12 45.9 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 EPS27018.1 - 0.0083 15.4 0.0 0.025 13.8 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 57 7TMR-DISMED2 PF07696.11 EPS27018.1 - 0.092 12.8 0.5 1.9 8.5 0.1 2.5 2 0 0 2 2 2 0 7TMR-DISM extracellular 2 NuA4 PF09340.10 EPS27019.1 - 1e-26 92.6 0.5 1e-26 92.6 0.5 1.7 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Ctr PF04145.15 EPS27020.1 - 5.6e-29 101.7 1.4 7.5e-29 101.3 1.4 1.2 1 0 0 1 1 1 1 Ctr copper transporter family Cupin_8 PF13621.6 EPS27021.1 - 3.3e-14 53.2 0.1 5.6e-12 45.9 0.1 2.2 1 1 0 1 1 1 1 Cupin-like domain F-box-like PF12937.7 EPS27021.1 - 2.1e-11 43.5 0.0 4.1e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 F-box-like JmjC PF02373.22 EPS27021.1 - 3.2e-10 40.5 0.0 1.5e-09 38.2 0.0 2.0 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box PF00646.33 EPS27021.1 - 4.5e-08 32.8 0.0 9.8e-08 31.7 0.0 1.6 1 0 0 1 1 1 1 F-box domain DEAD PF00270.29 EPS27022.1 - 1.1e-44 152.2 0.8 2.2e-44 151.3 0.8 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPS27022.1 - 1.7e-31 108.8 0.2 1.2e-30 106.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPS27022.1 - 4.8e-06 26.7 0.0 8.1e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EPS27022.1 - 0.00014 21.6 0.1 0.00026 20.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EPS27022.1 - 0.00036 20.9 0.3 0.002 18.5 0.2 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EPS27022.1 - 0.003 17.8 0.6 0.012 15.9 0.6 2.0 1 1 0 1 1 1 1 AAA domain CMS1 PF14617.6 EPS27022.1 - 0.019 14.3 0.0 0.039 13.3 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Helicase_RecD PF05127.14 EPS27022.1 - 0.12 12.2 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Helicase IL17R_D_N PF16742.5 EPS27022.1 - 0.15 12.1 0.0 0.41 10.7 0.0 1.6 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D Avl9 PF09794.9 EPS27023.1 - 0.18 10.5 0.0 0.22 10.2 0.0 1.1 1 0 0 1 1 1 0 Transport protein Avl9 UDPGT PF00201.18 EPS27025.1 - 5.7e-12 45.2 0.0 7.9e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase CelTOS PF18659.1 EPS27025.1 - 0.094 13.2 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 Cell-traversal protein for ookinetes and sporozoites Glyco_tran_28_C PF04101.16 EPS27025.1 - 0.17 11.9 0.0 5.5 6.9 0.0 2.2 2 0 0 2 2 2 0 Glycosyltransferase family 28 C-terminal domain MatE PF01554.18 EPS27027.1 - 1e-07 31.8 17.0 0.00058 19.6 1.5 3.7 3 1 0 3 3 3 3 MatE PWI PF01480.17 EPS27028.1 - 1.1e-31 108.9 0.1 1.7e-31 108.4 0.1 1.3 1 0 0 1 1 1 1 PWI domain Fmp27_WPPW PF10359.9 EPS27028.1 - 0.15 10.9 0.9 0.22 10.4 0.9 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Pkinase PF00069.25 EPS27034.1 - 1.9e-47 161.9 0.0 3e-47 161.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS27034.1 - 1.6e-16 60.4 0.0 2.4e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EPS27034.1 - 0.0014 18.3 0.2 0.003 17.2 0.2 1.5 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 EPS27034.1 - 0.0015 17.9 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EPS27034.1 - 0.017 15.1 0.1 0.23 11.4 0.1 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EPS27034.1 - 0.044 13.1 0.1 0.083 12.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EPS27034.1 - 0.06 12.1 0.0 0.06 12.1 0.0 2.5 3 0 0 3 3 3 0 Fungal protein kinase Ribosomal_S8e PF01201.22 EPS27035.1 - 4.3e-46 156.5 3.5 6.2e-46 156.0 3.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S8e CPP1-like PF11833.8 EPS27035.1 - 0.62 9.7 2.1 1.2 8.8 2.1 1.5 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Pannexin_like PF12534.8 EPS27035.1 - 7.5 5.5 6.6 10 5.1 6.6 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 TAF4 PF05236.14 EPS27035.1 - 10 5.8 13.9 10 5.7 10.8 1.9 1 1 1 2 2 2 0 Transcription initiation factor TFIID component TAF4 family Ribosomal_L21p PF00829.21 EPS27036.1 - 5.7e-08 32.9 0.0 7.8e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Anillin_N PF16018.5 EPS27037.1 - 0.016 15.8 0.5 0.017 15.7 0.5 1.2 1 0 0 1 1 1 0 Anillin N-terminus Fungal_trans PF04082.18 EPS27038.1 - 2.6e-18 66.0 0.1 4.3e-18 65.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS27038.1 - 0.0029 17.7 5.4 0.0073 16.4 5.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_pol_Rpb4 PF03874.16 EPS27040.1 - 4e-26 91.7 2.2 5.8e-26 91.2 2.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 Cut8 PF08559.10 EPS27040.1 - 0.0097 15.5 1.5 0.012 15.2 1.5 1.2 1 1 0 1 1 1 1 Cut8, nuclear proteasome tether protein Met_10 PF02475.16 EPS27041.1 - 4.7e-65 219.1 0.0 7.1e-65 218.5 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein TRM PF02005.16 EPS27041.1 - 0.12 11.6 0.0 0.25 10.5 0.0 1.4 2 0 0 2 2 2 0 N2,N2-dimethylguanosine tRNA methyltransferase Pro-kuma_activ PF09286.11 EPS27042.1 - 8.4e-33 113.7 0.1 3.6e-32 111.6 0.0 2.1 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EPS27042.1 - 0.0024 17.2 0.0 0.0046 16.3 0.0 1.4 1 0 0 1 1 1 1 Subtilase family Cofac_haem_bdg PF04187.13 EPS27043.1 - 0.0052 16.8 0.1 0.0085 16.1 0.1 1.4 1 1 0 1 1 1 1 Haem-binding uptake, Tiki superfamily, ChaN TMF_DNA_bd PF12329.8 EPS27043.1 - 0.055 13.5 1.0 0.15 12.1 1.0 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF3818 PF12825.7 EPS27044.1 - 1.3e-129 432.1 2.0 2.2e-129 431.3 2.0 1.4 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 EPS27044.1 - 2e-38 131.3 0.9 3.7e-38 130.5 0.9 1.5 1 0 0 1 1 1 1 PX-associated PX PF00787.24 EPS27044.1 - 2.3e-13 50.1 0.1 1.2e-12 47.8 0.0 2.3 2 1 0 2 2 2 1 PX domain DUF3990 PF13151.6 EPS27045.1 - 0.009 15.7 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3990) zf-C2H2 PF00096.26 EPS27047.1 - 0.00011 22.5 18.2 0.0013 19.1 5.0 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPS27047.1 - 0.036 14.9 4.4 0.036 14.9 4.4 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EPS27047.1 - 0.41 11.0 4.8 0.81 10.1 4.0 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 EPS27047.1 - 0.49 10.9 12.8 9.4 6.9 1.3 3.8 3 0 0 3 3 3 0 Zinc-finger double domain zf-H2C2_5 PF13909.6 EPS27047.1 - 2.3 8.0 18.9 0.092 12.5 1.1 3.5 3 0 0 3 3 3 0 C2H2-type zinc-finger domain AAA PF00004.29 EPS27048.1 - 8.3e-48 162.2 0.0 3.7e-43 147.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EPS27048.1 - 1.3e-07 31.3 5.1 2e-05 24.3 0.1 2.9 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EPS27048.1 - 1.5e-05 25.4 0.2 0.02 15.3 0.0 3.9 4 0 0 4 4 3 1 AAA ATPase domain RuvB_N PF05496.12 EPS27048.1 - 0.00015 21.6 0.0 0.00043 20.1 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Parvo_NS1 PF01057.17 EPS27048.1 - 0.00055 19.1 0.0 0.00097 18.3 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_2 PF07724.14 EPS27048.1 - 0.0039 17.3 0.0 0.0098 16.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 EPS27048.1 - 0.0056 17.1 0.0 0.015 15.7 0.0 1.8 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 EPS27048.1 - 0.0069 15.6 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 EPS27048.1 - 0.007 16.6 0.0 0.046 14.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_25 PF13481.6 EPS27048.1 - 0.0082 15.7 0.1 0.055 13.1 0.0 2.5 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EPS27048.1 - 0.0095 15.7 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EPS27048.1 - 0.024 14.0 0.1 0.055 12.8 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EPS27048.1 - 0.028 14.0 0.0 0.06 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 EPS27048.1 - 0.036 13.4 0.0 0.082 12.2 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.6 EPS27048.1 - 0.04 14.5 0.0 0.11 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EPS27048.1 - 0.041 13.9 0.0 0.13 12.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 EPS27048.1 - 0.075 13.0 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 EPS27048.1 - 0.1 12.1 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.6 EPS27048.1 - 0.13 12.5 0.0 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain MAGE_N PF12440.8 EPS27048.1 - 5.8 7.7 10.2 0.79 10.4 5.1 2.2 2 0 0 2 2 1 0 Melanoma associated antigen family N terminal RNase_T PF00929.24 EPS27051.1 - 4.5e-10 40.3 0.0 1e-09 39.1 0.0 1.6 2 0 0 2 2 2 1 Exonuclease DNA_pol_A_exo1 PF01612.20 EPS27051.1 - 0.0042 16.8 0.0 0.017 14.8 0.0 1.9 1 1 0 1 1 1 1 3'-5' exonuclease Sugar_tr PF00083.24 EPS27052.1 - 7.5e-94 315.1 32.1 9.2e-94 314.8 32.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS27052.1 - 3.1e-28 98.7 65.1 2e-25 89.5 36.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EPS27052.1 - 0.00028 19.5 6.1 0.00028 19.5 6.1 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) TPR_19 PF14559.6 EPS27052.1 - 0.011 16.2 0.0 0.031 14.8 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat AA_permease_2 PF13520.6 EPS27055.1 - 2.2e-40 138.8 51.0 2.9e-40 138.4 51.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPS27055.1 - 1.2e-13 50.4 47.1 2.4e-13 49.5 47.1 1.4 1 1 0 1 1 1 1 Amino acid permease MFS_MOT1 PF16983.5 EPS27056.1 - 3.1e-62 207.9 27.4 2.8e-34 117.8 7.6 3.0 4 0 0 4 4 4 2 Molybdate transporter of MFS superfamily Sulfate_transp PF00916.20 EPS27056.1 - 0.00024 20.0 20.0 0.0005 18.9 0.4 2.7 2 1 0 2 2 2 2 Sulfate permease family WD40 PF00400.32 EPS27058.1 - 4.1e-09 36.9 5.2 4.1e-05 24.3 0.2 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat PQQ_2 PF13360.6 EPS27058.1 - 0.00064 19.4 0.1 0.0036 16.9 0.0 2.2 2 0 0 2 2 2 1 PQQ-like domain ANAPC4_WD40 PF12894.7 EPS27058.1 - 0.013 15.8 0.0 7.8 6.9 0.0 3.8 2 1 2 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain FAM76 PF16046.5 EPS27058.1 - 0.019 14.4 2.3 0.026 13.9 2.3 1.2 1 0 0 1 1 1 0 FAM76 protein Gryzun-like PF12742.7 EPS27058.1 - 0.061 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking FlxA PF14282.6 EPS27058.1 - 0.31 11.1 4.4 1.7 8.7 4.4 2.1 1 1 0 1 1 1 0 FlxA-like protein SlyX PF04102.12 EPS27058.1 - 6.9 7.4 6.4 16 6.2 6.4 1.6 1 0 0 1 1 1 0 SlyX CHD5 PF04420.14 EPS27058.1 - 8.5 6.2 6.8 16 5.3 6.8 1.4 1 0 0 1 1 1 0 CHD5-like protein LIAS_N PF16881.5 EPS27060.1 - 8e-28 97.0 0.0 1.7e-27 96.0 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 EPS27060.1 - 5.1e-15 56.2 0.0 7.9e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily HAD PF12710.7 EPS27061.1 - 4.9e-20 72.7 0.0 6.9e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EPS27061.1 - 1.3e-16 61.5 0.1 1.8e-16 61.1 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EPS27061.1 - 7.7e-09 35.7 0.0 4.9e-08 33.0 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EPS27061.1 - 0.0023 18.1 0.1 0.055 13.5 0.1 2.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 EPS27061.1 - 0.01 15.3 0.0 0.14 11.5 0.0 2.1 1 1 0 1 1 1 1 Putative Phosphatase DUF705 PF05152.12 EPS27061.1 - 0.11 11.9 0.1 0.16 11.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF705) S6PP PF05116.13 EPS27061.1 - 0.12 11.8 0.1 0.69 9.4 0.0 1.9 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase PAPS_reduct PF01507.19 EPS27062.1 - 6.3e-44 150.1 0.1 2.7e-43 148.0 0.0 1.8 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family HA PF03457.14 EPS27062.1 - 0.82 10.0 3.1 4.1 7.8 1.0 2.7 2 1 0 2 2 2 0 Helicase associated domain Glyco_hydro_30 PF02055.16 EPS27063.1 - 2e-36 125.7 2.5 3.1e-36 125.1 2.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 TIM-barrel domain Glyco_hydro_30C PF17189.4 EPS27063.1 - 4.4e-09 36.4 0.2 1.1e-08 35.2 0.2 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydro_59 PF02057.15 EPS27063.1 - 5e-05 22.7 0.2 7.7e-05 22.1 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Pkinase PF00069.25 EPS27066.1 - 9.3e-74 248.1 0.0 1.3e-73 247.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS27066.1 - 5.1e-36 124.3 0.0 7.3e-36 123.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 EPS27066.1 - 3.9e-18 66.0 0.0 1.6e-11 44.6 0.0 2.5 2 0 0 2 2 2 2 Adenylate sensor of SNF1-like protein kinase UBA_2 PF08587.11 EPS27066.1 - 2.5e-14 53.1 0.0 5.3e-14 52.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 EPS27066.1 - 2.2e-05 23.9 0.0 4.4e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EPS27066.1 - 0.00031 20.4 0.1 0.00075 19.2 0.1 1.6 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 EPS27066.1 - 0.014 14.3 0.1 0.023 13.6 0.1 1.4 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EPS27066.1 - 0.023 14.6 3.4 0.11 12.4 0.0 2.7 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 EPS27066.1 - 0.071 12.5 0.1 0.16 11.3 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YukC PF10140.9 EPS27066.1 - 0.081 11.7 0.1 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Pox_ser-thr_kin PF05445.11 EPS27066.1 - 0.15 11.0 0.2 0.24 10.3 0.2 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase UTP15_C PF09384.10 EPS27067.1 - 3.3e-54 182.6 0.5 3.3e-54 182.6 0.5 1.6 2 0 0 2 2 2 1 UTP15 C terminal WD40 PF00400.32 EPS27067.1 - 1.4e-18 66.8 2.8 0.00053 20.7 0.2 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS27067.1 - 2.2e-07 31.0 0.5 0.016 15.5 0.0 4.4 4 2 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 EPS27067.1 - 0.019 14.3 0.5 1.4 8.1 0.1 2.3 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Nup160 PF11715.8 EPS27067.1 - 0.058 12.0 0.4 0.37 9.4 0.1 2.4 2 1 1 3 3 3 0 Nucleoporin Nup120/160 LRS4 PF10422.9 EPS27067.1 - 0.098 12.2 0.7 0.17 11.5 0.7 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 DUF5122 PF17164.4 EPS27067.1 - 0.11 12.8 0.2 0.85 10.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5122) beta-propeller C2 PF00168.30 EPS27068.1 - 1.1e-15 57.7 0.0 1.9e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 C2 domain PhyH PF05721.13 EPS27069.1 - 8.6e-43 147.1 0.0 1e-42 146.8 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) RNA_pol_Rpb1_1 PF04997.12 EPS27070.1 - 3.1e-86 289.5 1.3 4.1e-86 289.1 0.4 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 EPS27070.1 - 8e-80 268.1 1.2 1.4e-79 267.3 1.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EPS27070.1 - 2.9e-72 242.3 0.1 1.1e-71 240.5 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EPS27070.1 - 2.1e-34 118.7 0.0 9.1e-34 116.7 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EPS27070.1 - 2.3e-27 95.1 0.1 8.9e-27 93.2 0.1 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Zn_clus PF00172.18 EPS27071.1 - 3.4e-09 36.7 6.0 6.7e-09 35.7 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf_CCCH_4 PF18345.1 EPS27072.1 - 6.2e-07 29.3 7.3 1.1e-06 28.5 7.3 1.4 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 EPS27072.1 - 1e-06 28.3 4.1 1.6e-06 27.7 4.1 1.3 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 EPS27072.1 - 0.00018 21.3 1.5 0.00029 20.7 1.5 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 EPS27072.1 - 0.015 15.5 0.4 0.043 14.0 0.4 1.8 1 0 0 1 1 1 0 Zinc-finger containing family zf-CCCH_2 PF14608.6 EPS27072.1 - 0.032 14.7 3.9 0.057 13.9 3.9 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 EPS27072.1 - 0.088 13.5 0.2 0.088 13.5 0.2 2.7 2 0 0 2 2 2 0 Torus domain Sec1 PF00995.23 EPS27073.1 - 2.7e-127 426.4 0.0 3.1e-127 426.2 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Flavi_DEAD PF07652.14 EPS27073.1 - 0.16 12.0 0.1 0.33 10.9 0.1 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain Spt5_N PF11942.8 EPS27075.1 - 0.19 12.7 2.1 0.31 12.0 1.2 1.8 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal FYVE PF01363.21 EPS27077.1 - 8.2e-21 73.9 25.0 2.3e-16 59.6 6.2 2.9 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 EPS27077.1 - 3.1e-17 62.0 0.4 7.6e-17 60.8 0.4 1.7 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-Di19 PF05605.12 EPS27077.1 - 0.00066 19.9 7.2 0.046 14.0 0.1 2.7 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-AN1 PF01428.16 EPS27077.1 - 0.0026 17.9 6.6 0.0026 17.9 6.6 3.9 3 1 1 4 4 4 1 AN1-like Zinc finger YqaH PF17448.2 EPS27077.1 - 0.032 14.5 0.2 0.083 13.2 0.2 1.7 1 0 0 1 1 1 0 Uncharacterized YqaH-like zf-C2H2_2 PF12756.7 EPS27077.1 - 0.38 11.1 0.0 0.38 11.1 0.0 3.4 3 1 0 4 4 4 0 C2H2 type zinc-finger (2 copies) UBZ_FAAP20 PF15750.5 EPS27077.1 - 0.49 10.4 5.3 9.5 6.3 0.5 2.7 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger zf-WRNIP1_ubi PF18279.1 EPS27077.1 - 0.65 10.8 4.6 7.2 7.5 0.3 2.8 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-TFIIB PF13453.6 EPS27077.1 - 0.83 9.0 5.8 6.3 6.2 0.0 3.7 3 0 0 3 3 3 0 Transcription factor zinc-finger HypA PF01155.19 EPS27077.1 - 1.2 9.2 12.2 0.32 11.0 0.1 3.5 4 0 0 4 4 4 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TMF_TATA_bd PF12325.8 EPS27077.1 - 6.1 7.1 10.2 0.36 11.1 0.9 2.8 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding IBR PF01485.21 EPS27077.1 - 7.5 6.9 21.0 0.11 12.7 3.3 3.4 3 1 1 4 4 4 0 IBR domain, a half RING-finger domain GLTP PF08718.11 EPS27079.1 - 5e-38 130.7 0.0 6.4e-38 130.4 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) PH_4 PF15404.6 EPS27080.1 - 4e-55 186.4 0.4 5e-54 182.9 0.2 2.8 2 1 0 2 2 2 1 Pleckstrin homology domain Spo7_2_N PF15407.6 EPS27080.1 - 1.3e-23 82.4 1.4 3.5e-23 81.0 1.4 1.8 1 0 0 1 1 1 1 Sporulation protein family 7 PH PF00169.29 EPS27080.1 - 7.1e-10 39.3 0.6 0.00053 20.5 0.0 4.9 4 1 0 4 4 4 2 PH domain PH_6 PF15406.6 EPS27080.1 - 0.07 13.4 0.1 2 8.7 0.0 2.6 2 0 0 2 2 2 0 Pleckstrin homology domain Peptidase_S24 PF00717.23 EPS27081.1 - 4.2e-08 33.0 0.0 1.1e-07 31.6 0.0 1.7 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 EPS27081.1 - 0.019 14.7 0.0 7.7 6.3 0.0 2.8 1 1 1 2 2 2 0 Signal peptidase, peptidase S26 Macro PF01661.21 EPS27082.1 - 7.1e-41 139.0 0.4 1.2e-40 138.2 0.4 1.4 1 0 0 1 1 1 1 Macro domain p450 PF00067.22 EPS27084.1 - 3.4e-17 62.4 0.0 4.3e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FhuF PF06276.12 EPS27085.1 - 1.1e-11 45.4 0.4 6.2e-05 23.5 0.1 2.3 1 1 1 2 2 2 2 Ferric iron reductase FhuF-like transporter IucA_IucC PF04183.12 EPS27085.1 - 2.2e-09 37.2 0.0 4.8e-09 36.1 0.0 1.5 2 0 0 2 2 2 1 IucA / IucC family Raftlin PF15250.6 EPS27085.1 - 0.2 10.4 0.0 0.25 10.0 0.0 1.1 1 0 0 1 1 1 0 Raftlin GATA PF00320.27 EPS27088.1 - 2.9e-15 55.6 5.3 6.2e-15 54.5 5.3 1.6 1 0 0 1 1 1 1 GATA zinc finger zinc_ribbon_9 PF14369.6 EPS27088.1 - 0.44 10.8 1.6 0.92 9.8 1.6 1.5 1 0 0 1 1 1 0 zinc-ribbon COesterase PF00135.28 EPS27092.1 - 7.3e-90 302.3 0.0 1.1e-89 301.7 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EPS27092.1 - 5e-07 29.8 0.4 0.0017 18.3 0.1 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EPS27092.1 - 0.00078 19.0 0.1 0.0014 18.2 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family GCS PF03074.16 EPS27093.1 - 3.6e-175 582.6 0.0 4.5e-175 582.3 0.0 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase NDUF_B7 PF05676.13 EPS27094.1 - 1.3e-29 101.7 7.2 1.6e-29 101.4 7.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 EPS27094.1 - 0.024 14.6 3.3 0.032 14.2 3.3 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF4674 PF15719.5 EPS27094.1 - 0.035 14.2 0.1 0.036 14.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4674) Ank_4 PF13637.6 EPS27095.1 - 6e-12 45.8 0.4 2.2e-07 31.3 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EPS27095.1 - 7.2e-12 45.7 1.4 0.00023 21.7 0.1 2.8 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EPS27095.1 - 5.8e-11 42.3 0.4 5.6e-08 32.9 0.2 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 EPS27095.1 - 1.1e-10 40.8 0.9 9.1e-06 25.7 0.2 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EPS27095.1 - 2e-09 37.5 1.1 8e-05 22.9 0.3 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) KilA-N PF04383.13 EPS27095.1 - 1.1e-05 25.3 0.0 4e-05 23.4 0.0 1.9 1 1 0 1 1 1 1 KilA-N domain GCH_III PF05165.12 EPS27095.1 - 0.044 13.0 0.0 0.084 12.1 0.0 1.4 1 0 0 1 1 1 0 GTP cyclohydrolase III KIAA1430 PF13879.6 EPS27095.1 - 1.6 9.5 8.5 3.6 8.4 0.4 3.2 3 1 0 3 3 3 0 KIAA1430 homologue DUF2322 PF10084.9 EPS27096.1 - 0.01 15.8 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2322) ThrE PF06738.12 EPS27097.1 - 1.9e-75 253.3 15.3 1.1e-69 234.5 2.6 2.3 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 EPS27097.1 - 7.3e-10 39.1 12.0 7.3e-10 39.1 12.0 2.5 2 1 0 2 2 2 1 Threonine/Serine exporter, ThrE MIS13 PF08202.11 EPS27098.1 - 1.3e-41 142.9 12.0 5.5e-41 140.8 4.9 3.1 2 1 0 2 2 2 1 Mis12-Mtw1 protein family TSC22 PF01166.18 EPS27098.1 - 0.065 13.6 0.5 0.16 12.3 0.5 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family ABC_tran_CTD PF16326.5 EPS27098.1 - 0.12 12.7 1.5 0.51 10.6 1.5 2.1 1 0 0 1 1 1 0 ABC transporter C-terminal domain DivIC PF04977.15 EPS27098.1 - 0.17 11.7 1.5 0.37 10.6 1.5 1.5 1 0 0 1 1 1 0 Septum formation initiator PS_Dcarbxylase PF02666.15 EPS27099.1 - 6.6e-55 185.8 0.0 1e-54 185.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 EPS27099.1 - 1.5e-22 79.8 0.0 2.2e-18 66.4 0.0 2.5 2 0 0 2 2 2 2 C2 domain EF-hand_1 PF00036.32 EPS27099.1 - 0.026 14.0 0.1 0.085 12.4 0.1 2.0 1 0 0 1 1 1 0 EF hand APH PF01636.23 EPS27100.1 - 1.2e-12 48.3 0.1 1.6e-12 47.9 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPS27100.1 - 0.014 15.0 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Sugar_tr PF00083.24 EPS27101.1 - 7.1e-94 315.2 13.0 9.2e-94 314.8 13.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS27101.1 - 2.2e-35 122.2 39.4 5.9e-26 91.2 17.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EPS27101.1 - 5.3e-08 32.6 3.6 5.3e-08 32.6 3.6 2.9 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 EPS27101.1 - 9.5e-06 24.3 2.4 9.5e-06 24.3 2.4 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EPS27101.1 - 0.06 11.6 4.8 0.058 11.7 2.9 2.0 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Pkinase PF00069.25 EPS27103.1 - 1.4e-62 211.4 0.0 1.8e-62 211.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS27103.1 - 4.1e-29 101.7 0.0 6.1e-29 101.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EPS27103.1 - 0.0019 17.2 0.1 0.0024 16.9 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain zf-UBR PF02207.20 EPS27104.1 - 6e-14 52.0 4.6 6e-14 52.0 4.6 3.1 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) Presenilin PF01080.17 EPS27104.1 - 0.16 10.7 2.6 0.22 10.3 2.6 1.1 1 0 0 1 1 1 0 Presenilin MCM PF00493.23 EPS27105.1 - 2.3e-101 337.6 0.0 3.5e-101 337.0 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EPS27105.1 - 2.3e-38 130.9 0.2 4.6e-38 129.9 0.2 1.5 1 0 0 1 1 1 1 MCM OB domain MCM2_N PF12619.8 EPS27105.1 - 9.6e-32 110.4 36.3 9.6e-32 110.4 36.3 2.3 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_lid PF17855.1 EPS27105.1 - 8.4e-25 87.0 0.9 2.1e-24 85.7 0.9 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EPS27105.1 - 2.2e-13 50.7 0.1 7.2e-13 49.0 0.1 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EPS27105.1 - 4.8e-09 35.9 0.1 7.4e-07 28.7 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EPS27105.1 - 6.7e-06 26.1 0.0 1.4e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EPS27105.1 - 0.00084 19.2 0.0 0.0051 16.7 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EPS27105.1 - 0.0018 18.0 0.1 0.012 15.4 0.1 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain Zn_ribbon_2 PF12674.7 EPS27105.1 - 0.014 16.0 0.3 0.042 14.5 0.3 1.8 1 0 0 1 1 1 0 Putative zinc ribbon domain AAA_16 PF13191.6 EPS27105.1 - 2.5 8.4 7.2 0.73 10.2 1.5 3.1 2 1 0 2 2 2 0 AAA ATPase domain Pal1 PF08316.11 EPS27106.1 - 3.5e-48 163.9 1.8 1.2e-47 162.1 1.8 2.0 1 1 0 1 1 1 1 Pal1 cell morphology protein Tannase PF07519.11 EPS27108.1 - 1.8e-102 343.7 0.8 2.1e-102 343.5 0.8 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.21 EPS27108.1 - 0.018 14.5 0.4 3.6 7.0 0.0 2.7 2 1 1 3 3 3 0 Prolyl oligopeptidase family Hydrolase_2 PF07486.12 EPS27108.1 - 0.13 13.1 0.0 0.31 11.9 0.0 1.6 1 0 0 1 1 1 0 Cell Wall Hydrolase Med31 PF05669.12 EPS27109.1 - 2.4e-31 107.6 0.1 2.9e-31 107.3 0.1 1.1 1 0 0 1 1 1 1 SOH1 Palm_thioest PF02089.15 EPS27111.1 - 4.6e-82 275.5 0.0 5.4e-82 275.3 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 EPS27111.1 - 0.015 14.7 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_6 PF12697.7 EPS27111.1 - 0.1 13.2 0.0 0.13 12.9 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF4661 PF15576.6 EPS27113.1 - 0.38 10.6 2.4 0.92 9.4 2.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) zf-C2H2 PF00096.26 EPS27113.1 - 5.7 7.6 8.5 4.3 8.0 0.4 3.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type KTI12 PF08433.10 EPS27114.1 - 1.2e-63 215.1 0.0 2.4e-63 214.1 0.0 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 EPS27114.1 - 0.0049 17.0 0.1 0.011 16.0 0.1 1.5 1 0 0 1 1 1 1 AAA domain Methyltransf_16 PF10294.9 EPS27115.1 - 1.9e-13 50.5 0.0 3.1e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EPS27115.1 - 0.011 15.6 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 EPS27115.1 - 0.18 11.1 0.0 0.25 10.7 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) NinD PF17466.2 EPS27116.1 - 0.075 13.1 0.1 0.14 12.3 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function Peptidase_C14 PF00656.22 EPS27120.1 - 4.5e-60 203.7 0.0 6e-60 203.3 0.0 1.1 1 0 0 1 1 1 1 Caspase domain F-box_4 PF15966.5 EPS27121.1 - 0.0034 17.2 0.0 0.0063 16.4 0.0 1.4 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 EPS27121.1 - 0.0063 16.4 1.0 0.014 15.3 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EPS27121.1 - 0.026 14.4 3.5 0.057 13.3 0.1 2.6 3 0 0 3 3 3 0 F-box domain bZIP_1 PF00170.21 EPS27122.1 - 2.2e-08 34.0 14.7 2.2e-07 30.9 12.3 2.3 1 1 1 2 2 2 2 bZIP transcription factor UPF0242 PF06785.11 EPS27122.1 - 0.00042 20.5 6.8 0.00061 20.0 6.8 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus bZIP_2 PF07716.15 EPS27122.1 - 0.0009 19.3 19.4 0.062 13.4 9.7 2.4 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_Maf PF03131.17 EPS27122.1 - 0.0023 18.4 11.5 0.0023 18.4 11.5 2.2 1 1 1 2 2 2 1 bZIP Maf transcription factor DUF812 PF05667.11 EPS27122.1 - 0.0031 16.5 6.8 0.0033 16.4 6.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) HALZ PF02183.18 EPS27122.1 - 0.0082 16.3 8.6 0.0098 16.1 0.9 2.5 2 0 0 2 2 2 1 Homeobox associated leucine zipper ATG16 PF08614.11 EPS27122.1 - 0.0083 16.4 10.3 0.012 15.8 10.3 1.3 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) YabA PF06156.13 EPS27122.1 - 0.0089 16.7 5.8 0.01 16.4 4.5 1.9 2 0 0 2 2 1 1 Initiation control protein YabA MPS2 PF17060.5 EPS27122.1 - 0.01 15.2 7.0 0.014 14.7 7.0 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 HAUS6_N PF14661.6 EPS27122.1 - 0.026 14.1 8.1 0.034 13.7 8.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF1640 PF07798.11 EPS27122.1 - 0.044 13.8 6.7 0.067 13.2 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) FUSC PF04632.12 EPS27122.1 - 0.057 12.0 1.1 0.071 11.6 1.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family TSNAXIP1_N PF15739.5 EPS27122.1 - 0.06 13.7 6.3 0.12 12.7 6.3 1.5 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus DUF724 PF05266.14 EPS27122.1 - 0.06 13.2 4.8 0.094 12.5 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ADIP PF11559.8 EPS27122.1 - 0.063 13.4 11.1 0.1 12.7 11.1 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 EPS27122.1 - 0.073 13.6 10.2 0.14 12.7 10.2 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region PI3K_P85_iSH2 PF16454.5 EPS27122.1 - 0.077 12.6 9.9 0.13 11.9 9.9 1.3 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain TMF_TATA_bd PF12325.8 EPS27122.1 - 0.1 12.8 10.2 0.49 10.6 9.8 2.1 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Seryl_tRNA_N PF02403.22 EPS27122.1 - 0.1 12.9 8.0 0.16 12.2 8.0 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4446 PF14584.6 EPS27122.1 - 0.15 12.0 3.6 0.25 11.3 3.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) FAM76 PF16046.5 EPS27122.1 - 0.25 10.6 6.7 0.32 10.3 6.7 1.1 1 0 0 1 1 1 0 FAM76 protein Cnn_1N PF07989.11 EPS27122.1 - 0.31 11.2 9.0 1 9.6 8.9 1.9 1 1 0 1 1 1 0 Centrosomin N-terminal motif 1 ZapB PF06005.12 EPS27122.1 - 0.37 11.2 12.9 0.3 11.6 10.8 1.9 1 1 1 2 2 2 0 Cell division protein ZapB Cep57_CLD_2 PF14197.6 EPS27122.1 - 0.48 10.5 11.5 0.93 9.6 11.5 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 COMP PF11598.8 EPS27122.1 - 0.49 10.9 3.8 0.2 12.1 1.2 1.8 2 0 0 2 2 1 0 Cartilage oligomeric matrix protein DUF349 PF03993.12 EPS27122.1 - 1.5 9.2 9.1 2.9 8.2 9.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) FapA PF03961.13 EPS27122.1 - 2.7 6.5 5.5 3.7 6.1 5.5 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Mto2_bdg PF12808.7 EPS27122.1 - 3.6 8.0 13.7 0.25 11.6 0.9 2.5 1 1 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DivIC PF04977.15 EPS27122.1 - 3.9 7.3 11.2 1.1 9.1 5.2 2.4 1 1 1 2 2 2 0 Septum formation initiator DUF5595 PF18077.1 EPS27122.1 - 5.5 7.1 6.8 11 6.2 0.9 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5595) OmpH PF03938.14 EPS27122.1 - 7.8 6.8 13.1 8.3 6.7 2.5 2.0 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Csm1_N PF18504.1 EPS27122.1 - 8.5 6.8 12.2 13 6.2 4.3 2.3 1 1 1 2 2 2 0 Csm1 N-terminal domain Fungal_trans_2 PF11951.8 EPS27123.1 - 1.1e-07 31.1 2.8 2.8e-07 29.7 2.7 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF3712 PF12505.8 EPS27124.1 - 7.2e-33 113.5 2.4 1.5e-32 112.5 2.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) DUF2236 PF09995.9 EPS27125.1 - 5.5e-39 134.7 5.0 7.4e-39 134.3 5.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) MDMPI_C PF07398.11 EPS27125.1 - 0.0056 17.5 0.1 0.21 12.4 0.0 2.3 2 0 0 2 2 2 1 MDMPI C-terminal domain SOBP PF15279.6 EPS27126.1 - 6.9 7.2 7.5 10 6.6 7.5 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein CsbD PF05532.12 EPS27128.1 - 4.4e-18 64.9 24.5 2.2e-11 43.5 6.7 3.4 3 1 0 3 3 3 2 CsbD-like Grg1 PF11034.8 EPS27128.1 - 0.18 12.0 0.3 0.18 12.0 0.3 2.9 1 1 1 3 3 3 0 Glucose-repressible protein Grg1 IDO PF01231.18 EPS27129.1 - 6.5e-162 539.2 0.0 7.5e-162 539.0 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.11 EPS27129.1 - 0.03 13.1 0.0 0.089 11.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1864) AA_permease_2 PF13520.6 EPS27131.1 - 2.8e-51 174.7 41.0 3.7e-51 174.3 41.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPS27131.1 - 3.8e-22 78.5 36.0 5.7e-22 78.0 36.0 1.2 1 0 0 1 1 1 1 Amino acid permease ORC5_C PF14630.6 EPS27132.1 - 0.092 12.2 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus MgtE PF01769.16 EPS27132.1 - 3.8 7.9 20.1 0.17 12.3 0.8 3.2 1 1 1 2 2 2 0 Divalent cation transporter Aminotran_5 PF00266.19 EPS27133.1 - 8.1e-94 314.6 0.0 1.1e-93 314.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EPS27133.1 - 1.8e-06 27.5 0.1 3.6e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EPS27133.1 - 8.1e-05 22.1 0.1 0.00026 20.4 0.0 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family BAR PF03114.18 EPS27134.1 - 1.3e-66 224.6 9.9 1.6e-66 224.3 9.9 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 EPS27134.1 - 4.4e-15 55.0 0.1 8.8e-15 54.1 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EPS27134.1 - 4.4e-11 42.5 0.1 7.3e-11 41.8 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EPS27134.1 - 1.1e-10 41.0 0.2 3.4e-10 39.5 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain Vps5 PF09325.10 EPS27134.1 - 0.02 14.4 7.6 0.83 9.1 3.7 2.2 2 0 0 2 2 2 0 Vps5 C terminal like TMPIT PF07851.13 EPS27134.1 - 0.031 13.5 7.2 0.23 10.7 0.1 2.2 1 1 1 2 2 2 0 TMPIT-like protein BRE1 PF08647.11 EPS27134.1 - 0.052 13.6 11.8 0.06 13.4 0.9 2.6 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase CT_C_D PF02682.16 EPS27134.1 - 0.053 13.3 0.5 0.11 12.2 0.5 1.5 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D APG6_N PF17675.1 EPS27134.1 - 0.15 12.6 10.5 2.6 8.6 6.1 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region YlqD PF11068.8 EPS27134.1 - 0.45 10.9 4.2 1.5 9.2 0.1 2.5 2 0 0 2 2 2 0 YlqD protein BAR_3 PF16746.5 EPS27134.1 - 0.56 9.9 10.7 1.5 8.5 10.7 1.8 1 1 0 1 1 1 0 BAR domain of APPL family STE2 PF02116.15 EPS27135.1 - 1.4e-105 352.7 18.7 1.7e-105 352.4 18.7 1.1 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR O-ag_pol_Wzy PF14296.6 EPS27135.1 - 0.0013 17.5 13.6 0.0013 17.5 13.6 1.3 2 0 0 2 2 2 1 O-antigen polysaccharide polymerase Wzy HNH_2 PF13391.6 EPS27136.1 - 0.007 16.5 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease Oxidored_FMN PF00724.20 EPS27137.1 - 6.4e-66 223.0 0.0 7.3e-66 222.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family UEV PF05743.13 EPS27138.1 - 3.2e-39 133.5 0.1 5.6e-39 132.7 0.1 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 EPS27138.1 - 1.1e-20 73.3 0.1 2.8e-20 72.0 0.0 1.8 2 0 0 2 2 2 1 Vps23 core domain UQ_con PF00179.26 EPS27138.1 - 0.0022 17.7 0.1 0.0022 17.7 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Striatin PF08232.12 EPS27138.1 - 0.082 13.5 0.1 0.16 12.5 0.1 1.4 1 0 0 1 1 1 0 Striatin family KASH_CCD PF14662.6 EPS27138.1 - 0.17 11.7 0.5 0.28 11.0 0.5 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH APH PF01636.23 EPS27139.1 - 0.04 13.8 0.0 0.054 13.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Chitin_synth_1 PF01644.17 EPS27140.1 - 1.4e-68 230.0 0.0 2e-68 229.5 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EPS27140.1 - 2.5e-28 97.9 0.0 4.3e-28 97.1 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EPS27140.1 - 1.2e-24 86.8 0.0 1.5e-20 73.4 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EPS27140.1 - 2e-09 37.7 0.1 2e-09 37.7 0.1 2.8 4 0 0 4 4 4 1 Glycosyl transferase family group 2 UQ_con PF00179.26 EPS27141.1 - 2.9e-39 133.9 0.0 4e-39 133.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EPS27141.1 - 0.025 14.3 0.1 0.031 14.0 0.1 1.3 1 1 0 1 1 1 0 Prokaryotic E2 family B APH PF01636.23 EPS27142.1 - 3.9e-14 53.2 0.0 7.6e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPS27142.1 - 0.0012 18.5 0.0 0.0057 16.3 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase DUF1679 PF07914.11 EPS27142.1 - 0.011 14.6 0.0 0.21 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) TAF8_C PF10406.9 EPS27144.1 - 4.9e-22 78.2 0.3 1.7e-21 76.5 0.3 2.0 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 EPS27144.1 - 1.3e-06 28.3 0.0 2.6e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated Mitochondr_Som1 PF11093.8 EPS27145.1 - 1e-21 76.7 0.0 1.3e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial export protein Som1 AAA_25 PF13481.6 EPS27146.1 - 0.0056 16.3 0.1 0.064 12.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain Rad51 PF08423.11 EPS27146.1 - 0.014 14.6 0.0 0.14 11.4 0.0 2.1 1 1 0 1 1 1 0 Rad51 PALP PF00291.25 EPS27147.1 - 6.4e-70 235.9 0.4 8.8e-70 235.4 0.4 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme IlvN PF07991.12 EPS27148.1 - 9e-46 155.5 0.0 1.5e-45 154.7 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 EPS27148.1 - 4.5e-40 137.3 0.0 7e-40 136.6 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain 2OG-FeII_Oxy_2 PF13532.6 EPS27149.1 - 1.2e-25 90.8 0.0 2.5e-25 89.8 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.20 EPS27149.1 - 5.5e-25 88.5 0.0 5.9e-24 85.2 0.0 2.4 1 1 0 1 1 1 1 Isochorismatase family GST_C_2 PF13410.6 EPS27149.1 - 3.2e-05 23.8 0.1 0.0001 22.2 0.1 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 EPS27149.1 - 0.03 14.2 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Lipase_GDSL_2 PF13472.6 EPS27150.1 - 3e-12 47.3 0.7 3.6e-12 47.0 0.7 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EPS27150.1 - 2.1e-08 34.4 0.0 2.7e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ALGX PF16822.5 EPS27150.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 SGNH hydrolase-like domain, acetyltransferase AlgX ECH_1 PF00378.20 EPS27151.1 - 3.5e-38 131.3 0.4 9.3e-38 130.0 0.4 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EPS27151.1 - 2.4e-27 96.3 0.1 3.5e-26 92.5 0.1 1.9 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase HSP20 PF00011.21 EPS27152.1 - 2.2e-18 66.3 0.1 1.5e-16 60.4 0.1 2.2 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EPS27152.1 - 5.6e-05 22.6 0.0 0.00028 20.4 0.0 2.0 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Tfb5 PF06331.12 EPS27153.1 - 1.9e-22 79.0 1.1 2.4e-22 78.7 1.1 1.2 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 DUF1325 PF07039.11 EPS27153.1 - 0.12 12.4 0.2 0.13 12.4 0.2 1.1 1 0 0 1 1 1 0 SGF29 tudor-like domain MFS_1 PF07690.16 EPS27155.1 - 5.2e-37 127.6 57.1 1.1e-36 126.5 57.1 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS27155.1 - 2.7e-09 36.4 12.9 2.7e-09 36.4 12.9 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 EPS27155.1 - 2.1 6.5 13.0 0.48 8.6 3.3 2.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family HRXXH PF13933.6 EPS27156.1 - 1.3e-106 355.7 0.0 1.7e-106 355.3 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Aspzincin_M35 PF14521.6 EPS27156.1 - 2.4e-05 24.9 0.0 5e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase NAGLU PF05089.12 EPS27157.1 - 5e-135 449.7 8.6 7.8e-135 449.1 8.6 1.3 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 EPS27157.1 - 2e-74 250.5 7.6 3.4e-74 249.7 7.6 1.3 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.7 EPS27157.1 - 8.2e-20 70.4 0.0 2.2e-19 69.0 0.0 1.8 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Glyco_hydro_11 PF00457.17 EPS27158.1 - 5.9e-78 260.6 16.9 5.9e-78 260.6 16.9 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 11 CBM_1 PF00734.18 EPS27158.1 - 1.3e-10 41.0 19.8 1.3e-10 41.0 19.8 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain Toxin_7 PF05980.12 EPS27158.1 - 0.03 14.6 9.8 0.056 13.7 9.8 1.5 1 0 0 1 1 1 0 Toxin 7 Pollen_allerg_1 PF01357.21 EPS27159.1 - 3.7e-16 58.9 0.1 6.6e-16 58.1 0.1 1.4 1 0 0 1 1 1 1 Pollen allergen CBM_1 PF00734.18 EPS27159.1 - 9.7e-13 47.8 6.9 9.7e-13 47.8 6.9 3.5 4 0 0 4 4 4 1 Fungal cellulose binding domain MT0933_antitox PF14013.6 EPS27160.1 - 0.075 13.3 2.2 0.21 11.9 2.0 2.1 1 1 0 1 1 1 0 MT0933-like antitoxin protein TPR_12 PF13424.6 EPS27161.1 - 4.5e-27 94.1 28.8 2.6e-10 40.4 2.8 5.4 3 2 1 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 EPS27161.1 - 9.7e-11 41.2 29.4 0.05 13.5 0.5 7.4 7 0 0 7 7 7 4 Tetratricopeptide repeat PGAP1 PF07819.13 EPS27161.1 - 7.3e-07 29.1 0.0 1.4e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein TPR_MalT PF17874.1 EPS27161.1 - 9e-05 22.0 14.6 9e-05 22.0 14.6 2.0 2 0 0 2 2 2 1 MalT-like TPR region DUF676 PF05057.14 EPS27161.1 - 0.00015 21.4 0.0 0.00028 20.5 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) TPR_14 PF13428.6 EPS27161.1 - 0.0019 18.8 24.4 0.19 12.6 0.3 6.5 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 EPS27161.1 - 0.0031 17.6 17.6 0.058 13.6 0.6 5.2 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EPS27161.1 - 0.0033 17.4 1.2 0.0033 17.4 1.2 5.8 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 EPS27161.1 - 0.0059 16.5 0.3 0.0059 16.5 0.3 4.9 6 0 0 6 6 5 1 Tetratricopeptide repeat Abhydrolase_6 PF12697.7 EPS27161.1 - 0.0073 16.9 0.0 0.024 15.2 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family CREPT PF16566.5 EPS27161.1 - 0.019 15.1 0.2 0.062 13.5 0.2 1.8 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour DUF2664 PF10867.8 EPS27161.1 - 0.02 15.3 1.7 3.8 8.0 0.3 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF2664) TPR_1 PF00515.28 EPS27161.1 - 0.02 14.7 17.5 0.02 14.7 1.6 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat Hydrolase_4 PF12146.8 EPS27161.1 - 0.029 13.6 0.0 0.071 12.4 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 UPF0149 PF03695.13 EPS27161.1 - 0.042 14.1 0.2 0.042 14.1 0.2 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0149) TPR_19 PF14559.6 EPS27161.1 - 0.056 14.0 19.2 2.5 8.7 1.8 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Palm_thioest PF02089.15 EPS27161.1 - 0.059 13.2 0.0 0.097 12.5 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 EPS27161.1 - 0.067 12.8 0.0 0.23 11.1 0.0 1.9 1 0 0 1 1 1 0 alpha/beta hydrolase fold Cutinase PF01083.22 EPS27161.1 - 0.086 12.8 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Cutinase Lipase_3 PF01764.25 EPS27161.1 - 0.16 11.8 0.0 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 Lipase (class 3) TPR_11 PF13414.6 EPS27161.1 - 2.5 7.9 5.5 7.7 6.3 0.0 3.1 3 0 0 3 3 3 0 TPR repeat TPR_16 PF13432.6 EPS27161.1 - 3.6 8.3 22.0 0.12 13.0 0.8 4.5 4 1 0 4 4 3 0 Tetratricopeptide repeat Cu_amine_oxid PF01179.20 EPS27162.1 - 8.6e-164 545.3 0.1 1e-163 545.0 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 EPS27162.1 - 0.002 18.5 0.0 0.0044 17.4 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 EPS27162.1 - 0.0082 16.4 0.1 0.018 15.2 0.1 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Peptidase_M99 PF17033.5 EPS27162.1 - 0.19 11.1 0.2 0.33 10.3 0.2 1.2 1 0 0 1 1 1 0 Carboxypeptidase controlling helical cell shape catalytic Abhydrolase_1 PF00561.20 EPS27163.1 - 4.7e-17 62.5 0.0 7.8e-16 58.5 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPS27163.1 - 2e-12 48.2 0.0 2.5e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPS27163.1 - 2.1e-11 43.5 0.0 5.2e-11 42.3 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 EPS27163.1 - 0.0052 16.6 0.0 0.18 11.5 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Ndr PF03096.14 EPS27163.1 - 0.053 12.2 0.0 0.2 10.3 0.0 1.9 1 1 0 1 1 1 0 Ndr family AXE1 PF05448.12 EPS27163.1 - 0.18 10.4 0.0 0.55 8.8 0.0 1.8 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) MFS_1 PF07690.16 EPS27164.1 - 1.1e-27 96.9 54.1 1.2e-23 83.7 34.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS27164.1 - 2.3e-15 56.4 25.4 4.8e-13 48.8 6.3 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter LacAB_rpiB PF02502.18 EPS27164.1 - 0.38 10.7 1.0 1.2 9.1 1.0 1.7 2 0 0 2 2 2 0 Ribose/Galactose Isomerase Glyco_hydro_3_C PF01915.22 EPS27165.1 - 6.5e-55 186.2 0.0 1e-54 185.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EPS27165.1 - 7.7e-41 140.5 0.0 1.3e-40 139.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EPS27165.1 - 1.2e-22 79.8 0.0 2.4e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.12 EPS27165.1 - 2.6e-16 59.8 0.1 9.8e-16 57.9 0.0 1.9 2 0 0 2 2 2 1 PA14 domain Sugar_tr PF00083.24 EPS27166.1 - 5e-70 236.6 21.1 6.6e-70 236.2 21.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS27166.1 - 1.8e-20 73.2 27.7 7.7e-20 71.1 15.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EPS27166.1 - 0.00011 20.9 5.1 0.00011 20.9 5.1 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.13 EPS27166.1 - 0.0087 14.5 2.1 0.014 13.9 2.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Chal_sti_synt_N PF00195.19 EPS27167.1 - 1.3e-31 109.7 0.1 3.7e-31 108.3 0.0 1.6 2 0 0 2 2 2 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.15 EPS27167.1 - 8.2e-18 64.8 0.0 1.6e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain FAE1_CUT1_RppA PF08392.12 EPS27167.1 - 2.7e-07 30.2 0.1 4.3e-07 29.5 0.1 1.3 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III PF08545.10 EPS27167.1 - 7.3e-07 29.0 1.1 2.7e-06 27.1 1.1 2.0 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 EPS27167.1 - 0.0048 17.0 0.1 0.027 14.6 0.0 2.3 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Sulfotransfer_4 PF17784.1 EPS27168.1 - 5.3e-55 186.6 0.0 6.2e-55 186.3 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EPS27168.1 - 0.0008 19.8 0.1 0.2 12.0 0.0 2.2 1 1 1 2 2 2 2 Sulfotransferase family SHR3_chaperone PF08229.11 EPS27170.1 - 0.022 13.7 0.6 0.049 12.6 0.5 1.7 1 1 0 1 1 1 0 ER membrane protein SH3 Saf_2TM PF18303.1 EPS27170.1 - 0.025 14.2 0.1 0.059 13.0 0.1 1.6 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain Pox_EPC_I2-L1 PF12575.8 EPS27170.1 - 0.72 10.1 5.5 4.4 7.6 0.1 3.0 2 1 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 DUF1700 PF08006.11 EPS27170.1 - 0.78 9.2 4.6 1.6 8.2 4.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DUF3311 PF11755.8 EPS27170.1 - 2 8.4 9.7 0.58 10.1 2.9 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3311) Lig_chan PF00060.26 EPS27170.1 - 2.2 8.1 6.0 2.6 7.9 5.0 1.6 1 1 0 1 1 1 0 Ligand-gated ion channel DUF898 PF05987.13 EPS27170.1 - 5.9 5.8 12.1 4e+02 -0.2 12.1 2.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) p450 PF00067.22 EPS27171.1 - 3.4e-51 174.5 0.0 4.3e-51 174.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SUR7 PF06687.12 EPS27172.1 - 3.4 7.2 9.1 0.54 9.8 0.6 2.5 2 1 1 3 3 3 0 SUR7/PalI family DUF3632 PF12311.8 EPS27173.1 - 6e-33 114.7 2.8 7.7e-33 114.4 2.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) AraC_binding PF02311.19 EPS27173.1 - 0.19 11.6 0.3 0.54 10.2 0.1 1.8 2 0 0 2 2 2 0 AraC-like ligand binding domain FAD_binding_3 PF01494.19 EPS27175.1 - 1.2e-17 64.3 0.0 1.3e-08 34.5 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EPS27175.1 - 3.5e-10 40.0 0.2 1e-05 25.3 0.2 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.22 EPS27175.1 - 3e-06 26.6 0.0 8.4e-06 25.1 0.0 1.6 1 1 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 EPS27175.1 - 2.1e-05 23.9 0.0 4.9e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPS27175.1 - 2.2e-05 24.9 0.0 0.0071 16.9 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPS27175.1 - 2.2e-05 24.6 0.1 4.9e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EPS27175.1 - 0.00039 19.6 0.3 0.0037 16.4 0.2 2.3 3 0 0 3 3 3 1 FAD binding domain HI0933_like PF03486.14 EPS27175.1 - 0.0025 16.6 0.1 0.0072 15.1 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 EPS27175.1 - 0.0027 17.1 0.0 0.005 16.2 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EPS27175.1 - 0.0031 16.4 0.0 0.0064 15.4 0.0 1.5 2 0 0 2 2 2 1 Tryptophan halogenase SE PF08491.10 EPS27175.1 - 0.0041 16.2 0.0 1.5 7.8 0.0 2.3 2 1 0 2 2 2 2 Squalene epoxidase Thi4 PF01946.17 EPS27175.1 - 0.0045 16.3 0.1 0.0093 15.2 0.1 1.5 1 0 0 1 1 1 1 Thi4 family AlaDh_PNT_C PF01262.21 EPS27175.1 - 0.011 15.1 0.1 0.017 14.4 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 EPS27175.1 - 0.013 14.5 0.1 0.041 12.9 0.2 1.7 3 0 0 3 3 3 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EPS27175.1 - 0.037 13.3 0.0 0.49 9.6 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EPS27175.1 - 0.065 12.5 0.4 0.77 9.0 0.0 2.5 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Methyltransf_2 PF00891.18 EPS27176.1 - 5.1e-21 75.0 0.0 7.7e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 EPS27176.1 - 0.00028 20.8 0.0 0.00054 19.9 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain Dimerisation PF08100.11 EPS27176.1 - 0.00036 20.5 0.1 0.00083 19.3 0.1 1.7 1 0 0 1 1 1 1 Dimerisation domain p450 PF00067.22 EPS27178.1 - 2.6e-31 108.9 0.0 3.8e-31 108.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.18 EPS27180.1 - 8.5e-22 77.5 0.0 1.4e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 EPS27180.1 - 4.1e-05 23.5 0.0 9.3e-05 22.3 0.0 1.6 1 1 0 1 1 1 1 Dimerisation domain Methyltransf_23 PF13489.6 EPS27180.1 - 0.0057 16.5 0.0 0.015 15.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Dimerisation PF08100.11 EPS27180.1 - 0.015 15.3 0.4 0.07 13.2 0.0 2.3 3 0 0 3 3 3 0 Dimerisation domain Methyltransf_19 PF04672.12 EPS27180.1 - 0.098 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl methyltransferase Cytochrom_B561 PF03188.16 EPS27183.1 - 1.8e-10 41.1 0.3 3.5e-10 40.2 0.3 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 tRNA-synt_2b PF00587.25 EPS27184.1 - 1.1e-06 28.8 0.0 1.2e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Cu-oxidase_3 PF07732.15 EPS27185.1 - 2.6e-29 101.7 0.2 6.7e-29 100.3 0.2 1.8 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.22 EPS27185.1 - 4.6e-26 91.8 0.0 8.7e-24 84.4 0.0 2.3 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.14 EPS27185.1 - 1.5e-18 66.8 6.0 5.6e-15 55.3 0.8 3.4 3 1 0 3 3 3 2 Multicopper oxidase YpjP PF14005.6 EPS27186.1 - 0.0039 17.2 1.7 0.0043 17.1 1.7 1.1 1 0 0 1 1 1 1 YpjP-like protein Aerolysin PF01117.20 EPS27186.1 - 0.33 10.1 6.6 0.35 10.1 6.6 1.0 1 0 0 1 1 1 0 Aerolysin toxin ABC_tran PF00005.27 EPS27187.1 - 7.5e-43 146.3 1.0 4.1e-25 88.9 0.2 3.5 3 1 0 3 3 3 2 ABC transporter ABC_membrane PF00664.23 EPS27187.1 - 1.3e-31 110.2 27.0 2.5e-23 83.1 13.5 2.7 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EPS27187.1 - 1.5e-13 50.7 0.3 0.0022 17.5 1.4 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 EPS27187.1 - 5e-06 25.8 0.1 0.0082 15.2 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.6 EPS27187.1 - 6.1e-05 23.5 0.4 0.61 10.4 0.0 3.5 3 0 0 3 3 3 2 AAA ATPase domain AAA PF00004.29 EPS27187.1 - 0.00015 22.2 0.3 0.28 11.6 0.0 3.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EPS27187.1 - 0.0002 21.6 0.1 1.5 9.1 0.0 3.1 2 0 0 2 2 2 2 AAA domain cobW PF02492.19 EPS27187.1 - 0.0005 19.7 0.2 0.89 9.1 0.0 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.6 EPS27187.1 - 0.00086 19.2 2.5 4.6 7.0 0.0 4.3 5 1 1 6 6 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 EPS27187.1 - 0.0013 18.2 0.1 0.92 9.0 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_29 PF13555.6 EPS27187.1 - 0.0027 17.4 0.2 2.6 7.8 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_24 PF13479.6 EPS27187.1 - 0.0059 16.3 0.0 0.61 9.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EPS27187.1 - 0.0081 16.1 0.3 1.2 9.0 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase ATPase_2 PF01637.18 EPS27187.1 - 0.016 15.1 0.0 0.85 9.5 0.0 2.6 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 EPS27187.1 - 0.02 14.1 0.5 2.2 7.4 0.0 3.1 2 2 0 2 2 2 0 NB-ARC domain IstB_IS21 PF01695.17 EPS27187.1 - 0.022 14.5 0.8 4.9 6.8 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein MMR_HSR1 PF01926.23 EPS27187.1 - 0.041 14.0 0.0 7.9 6.6 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase DEAD PF00270.29 EPS27187.1 - 0.045 13.5 2.3 0.39 10.4 1.3 2.8 2 1 0 2 2 1 0 DEAD/DEAH box helicase AAA_23 PF13476.6 EPS27187.1 - 0.069 13.7 5.0 1.4 9.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain TsaE PF02367.17 EPS27187.1 - 0.073 13.1 0.1 4.8 7.2 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EPS27187.1 - 0.081 13.5 0.1 12 6.4 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EPS27187.1 - 0.085 12.6 0.0 1.9 8.2 0.0 2.6 3 0 0 3 3 3 0 AAA domain Viral_helicase1 PF01443.18 EPS27187.1 - 0.11 12.2 0.1 18 5.0 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 EPS27187.1 - 0.12 11.9 0.0 14 5.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EPS27187.1 - 0.35 10.9 1.4 13 5.8 0.0 2.7 3 0 0 3 3 2 0 Dynamin family AMP-binding PF00501.28 EPS27188.1 - 0 1697.5 0.0 1.2e-76 258.1 0.0 7.3 7 0 0 7 7 7 7 AMP-binding enzyme Condensation PF00668.20 EPS27188.1 - 1.9e-260 864.2 0.0 1.3e-41 142.7 0.0 9.2 9 0 0 9 9 9 9 Condensation domain PP-binding PF00550.25 EPS27188.1 - 2.1e-72 239.4 4.9 3.9e-12 46.3 0.3 8.4 7 0 0 7 7 7 7 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EPS27188.1 - 1.8e-15 57.7 0.2 1.5 9.8 0.0 7.4 7 0 0 7 7 7 5 AMP-binding enzyme C-terminal domain GH3 PF03321.13 EPS27188.1 - 0.33 9.8 7.3 47 2.7 0.0 5.5 8 0 0 8 8 8 0 GH3 auxin-responsive promoter Abhydrolase_6 PF12697.7 EPS27189.1 - 2.7e-15 57.6 1.2 3.8e-15 57.1 1.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EPS27189.1 - 1.6e-12 47.6 0.0 2.3e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EPS27189.1 - 1.9e-09 37.2 0.1 2.7e-09 36.7 0.1 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EPS27189.1 - 2e-07 31.4 0.1 3.4e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 Thioesterase domain Ser_hydrolase PF06821.13 EPS27189.1 - 0.0048 16.8 0.2 0.011 15.7 0.2 1.6 1 0 0 1 1 1 1 Serine hydrolase Pyr_redox_2 PF07992.14 EPS27190.1 - 2.1e-17 63.3 0.0 5e-17 62.1 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EPS27190.1 - 1.5e-05 24.3 0.5 2.9e-05 23.3 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 EPS27190.1 - 1.7e-05 24.9 1.0 0.066 13.2 1.0 2.4 1 1 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EPS27190.1 - 3.1e-05 24.1 0.1 0.00023 21.3 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EPS27190.1 - 0.00017 20.8 0.1 0.024 13.7 0.1 2.3 1 1 0 2 2 2 2 Glucose inhibited division protein A HI0933_like PF03486.14 EPS27190.1 - 0.00021 20.1 0.1 0.0021 16.8 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 EPS27190.1 - 0.00041 20.1 0.3 0.0012 18.6 0.3 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EPS27190.1 - 0.001 18.4 0.5 0.018 14.3 0.5 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EPS27190.1 - 0.0019 17.6 0.7 0.0047 16.3 0.3 1.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EPS27190.1 - 0.0076 15.5 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DIOX_N PF14226.6 EPS27191.1 - 1.4e-16 61.3 0.0 6.9e-16 59.1 0.0 2.1 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EPS27191.1 - 3.7e-16 59.4 0.0 6.9e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fas_alpha_ACP PF18325.1 EPS27192.1 - 1.2e-50 172.0 0.0 7.6e-50 169.4 0.0 2.3 2 0 0 2 2 2 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 EPS27192.1 - 8e-29 100.7 0.0 1.6e-28 99.8 0.0 1.4 1 0 0 1 1 1 1 Fatty acid synthase type I helical domain ketoacyl-synt PF00109.26 EPS27192.1 - 4.4e-20 72.3 0.0 8.3e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EPS27192.1 - 6.9e-11 42.2 0.3 8.1e-10 38.8 0.0 2.7 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.25 EPS27192.1 - 0.00059 19.3 0.0 0.0013 18.3 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase HLH PF00010.26 EPS27193.1 - 1.2e-09 38.0 0.7 4.8e-09 36.0 0.0 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF1729 PF08354.10 EPS27194.1 - 4.3e-139 463.3 0.0 7e-139 462.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 EPS27194.1 - 2.1e-60 204.9 0.0 1e-59 202.6 0.0 2.0 2 0 0 2 2 2 1 Acyl transferase domain SAT PF16073.5 EPS27194.1 - 6.9e-28 98.0 0.0 3.4e-27 95.7 0.0 2.2 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis FAS_meander PF17951.1 EPS27194.1 - 1.7e-22 79.8 0.0 3.7e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain MaoC_dehydratas PF01575.19 EPS27194.1 - 1.2e-21 76.5 0.0 2.6e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 EPS27194.1 - 3.3e-09 37.0 0.0 1.7e-08 34.6 0.0 2.2 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase FA_desaturase PF00487.24 EPS27195.1 - 1.7e-19 70.6 18.6 3.1e-19 69.8 18.6 1.3 1 0 0 1 1 1 1 Fatty acid desaturase FA_hydroxylase PF04116.13 EPS27196.1 - 8.2e-22 78.0 15.0 8.2e-22 78.0 15.0 1.6 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily HsbA PF12296.8 EPS27197.1 - 2.9e-18 66.4 0.0 1.4e-16 61.0 0.0 2.0 1 1 1 2 2 2 2 Hydrophobic surface binding protein A DUF1488 PF07369.11 EPS27197.1 - 0.036 14.1 0.2 0.18 11.8 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1488) KR PF08659.10 EPS27198.1 - 1.6e-58 197.6 1.0 4.3e-58 196.2 0.9 1.9 2 0 0 2 2 1 1 KR domain PS-DH PF14765.6 EPS27198.1 - 1.9e-58 198.1 0.0 3.5e-58 197.2 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 EPS27198.1 - 1.7e-49 169.1 1.1 3.2e-49 168.2 0.1 1.8 2 0 0 2 2 2 1 Acyl transferase domain ketoacyl-synt PF00109.26 EPS27198.1 - 2.3e-44 151.9 0.0 3e-43 148.2 0.0 2.3 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EPS27198.1 - 1.5e-29 102.4 0.1 3.7e-29 101.1 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EPS27198.1 - 8.9e-21 74.5 0.0 1.8e-20 73.5 0.0 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 EPS27198.1 - 7.8e-18 65.1 0.0 2.8e-17 63.3 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 EPS27198.1 - 3e-16 60.7 0.0 1.1e-15 58.9 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EPS27198.1 - 2.7e-13 50.0 0.1 1e-12 48.1 0.0 2.1 2 0 0 2 2 1 1 Zinc-binding dehydrogenase adh_short PF00106.25 EPS27198.1 - 1.5e-10 40.8 1.5 4.2e-10 39.4 0.2 2.4 3 0 0 3 3 3 1 short chain dehydrogenase Methyltransf_23 PF13489.6 EPS27198.1 - 1.7e-10 40.9 0.0 5.3e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPS27198.1 - 4.1e-09 37.0 0.0 1.5e-08 35.2 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS27198.1 - 1.1e-08 35.6 0.0 3.3e-08 34.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPS27198.1 - 1.2e-08 34.9 0.0 2.7e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 EPS27198.1 - 3.4e-06 26.8 0.1 9.5e-06 25.3 0.1 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 EPS27198.1 - 0.0014 19.0 0.0 0.0053 17.1 0.0 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 EPS27198.1 - 0.0093 15.4 0.1 0.016 14.6 0.1 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase DUF938 PF06080.12 EPS27198.1 - 0.014 15.1 0.0 0.049 13.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF938) ADH_N PF08240.12 EPS27198.1 - 0.023 14.6 0.0 0.056 13.3 0.0 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Methyltransf_16 PF10294.9 EPS27198.1 - 0.038 13.7 0.0 0.082 12.6 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Polysacc_synt_2 PF02719.15 EPS27198.1 - 0.074 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TetR_C_16 PF17920.1 EPS27198.1 - 0.097 12.9 0.1 0.4 10.9 0.1 2.1 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain 3Beta_HSD PF01073.19 EPS27198.1 - 0.13 11.3 0.0 0.23 10.4 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Pyr_redox_3 PF13738.6 EPS27199.1 - 1.7e-11 44.0 0.0 7.5e-09 35.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EPS27199.1 - 8.1e-10 37.7 0.0 3.9e-09 35.5 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EPS27199.1 - 1.6e-09 37.4 0.0 4.2e-07 29.4 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EPS27199.1 - 0.00049 19.4 0.1 0.41 9.8 0.1 2.4 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EPS27199.1 - 0.067 12.2 0.0 1.8 7.5 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein THF_DHG_CYH_C PF02882.19 EPS27199.1 - 0.091 12.1 0.3 8.3 5.7 0.0 2.7 2 1 1 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Hemerythrin PF01814.23 EPS27200.1 - 0.076 13.6 0.3 1 10.0 0.3 2.2 1 1 0 1 1 1 0 Hemerythrin HHE cation binding domain DUF4450 PF14614.6 EPS27200.1 - 0.21 11.1 0.0 0.29 10.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4450) Methyltransf_23 PF13489.6 EPS27201.1 - 2.1e-21 76.5 0.0 3.5e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPS27201.1 - 8.1e-13 48.9 0.0 1.9e-12 47.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPS27201.1 - 6.6e-12 45.5 0.0 1.3e-10 41.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS27201.1 - 1.3e-10 41.8 0.0 4.3e-10 40.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPS27201.1 - 4.9e-08 33.6 0.0 5.8e-07 30.2 0.0 2.4 2 1 0 2 2 1 1 Methyltransferase domain FtsJ PF01728.19 EPS27201.1 - 0.0036 17.4 0.0 0.0058 16.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.13 EPS27201.1 - 0.0067 15.9 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 EPS27201.1 - 0.008 15.7 0.0 0.021 14.3 0.0 1.7 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 EPS27201.1 - 0.029 13.9 0.0 0.042 13.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.9 EPS27201.1 - 0.033 13.9 0.0 0.055 13.2 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Ubie_methyltran PF01209.18 EPS27201.1 - 0.15 11.4 0.0 0.63 9.3 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 EPS27201.1 - 0.17 11.1 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain GPI-anchored PF10342.9 EPS27202.1 - 5e-18 65.7 2.8 5e-18 65.7 2.8 2.3 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Peptidase_M28 PF04389.17 EPS27203.1 - 2.6e-39 135.0 0.1 4e-39 134.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EPS27203.1 - 4.8e-13 48.9 3.0 5.5e-13 48.8 1.4 2.0 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.28 EPS27203.1 - 0.00038 20.2 0.0 0.00077 19.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.15 EPS27203.1 - 0.0098 15.4 0.2 0.023 14.2 0.0 1.6 2 0 0 2 2 2 1 Nicastrin SRP-alpha_N PF04086.13 EPS27205.1 - 0.3 11.0 19.8 0.38 10.6 19.8 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal AP3D1 PF06375.11 EPS27205.1 - 0.47 10.7 23.9 0.38 11.0 4.0 2.2 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Macoilin PF09726.9 EPS27205.1 - 3.7 6.0 17.4 4.3 5.8 17.4 1.1 1 0 0 1 1 1 0 Macoilin family Peptidase_S49_N PF08496.10 EPS27205.1 - 7.6 6.6 14.0 3.6 7.6 4.8 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal AAA PF00004.29 EPS27206.1 - 1.7e-16 60.9 0.0 3.6e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EPS27206.1 - 0.0008 19.7 0.3 0.0083 16.4 0.2 2.2 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.6 EPS27206.1 - 0.0011 19.4 0.1 0.0042 17.5 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 EPS27206.1 - 0.0016 18.6 0.0 0.0057 16.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EPS27206.1 - 0.0017 18.4 0.0 0.0044 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 EPS27206.1 - 0.0062 16.3 0.3 0.042 13.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EPS27206.1 - 0.01 15.6 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EPS27206.1 - 0.042 14.2 0.1 0.12 12.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EPS27206.1 - 0.1 12.8 0.0 0.33 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain Torsin PF06309.11 EPS27206.1 - 0.1 12.7 0.3 0.46 10.6 0.0 2.2 2 0 0 2 2 2 0 Torsin Mg_chelatase PF01078.21 EPS27206.1 - 0.1 11.9 0.8 0.46 9.8 0.2 2.1 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Ldh_1_C PF02866.18 EPS27207.1 - 1.4e-48 165.0 0.1 3e-48 163.9 0.1 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EPS27207.1 - 2.7e-43 147.4 0.0 7.5e-43 146.0 0.0 1.7 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EPS27207.1 - 0.00014 21.0 0.0 0.0002 20.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 EPS27207.1 - 0.0079 16.6 0.2 0.13 12.7 0.0 2.7 3 0 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 EPS27207.1 - 0.031 13.6 0.0 0.38 10.1 0.0 2.6 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain V-SNARE_C PF12352.8 EPS27208.1 - 6.7e-13 48.7 0.2 1.7e-12 47.4 0.2 1.7 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 EPS27208.1 - 0.00052 19.9 0.0 0.0014 18.5 0.0 1.7 1 0 0 1 1 1 1 Sec20 BAR_2 PF10455.9 EPS27208.1 - 0.019 14.1 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking CHDCT2 PF08074.11 EPS27208.1 - 0.024 14.8 0.4 1.6 8.9 0.5 2.1 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain Sigma70_r4 PF04545.16 EPS27208.1 - 0.089 12.3 0.2 0.23 11.0 0.2 1.8 1 0 0 1 1 1 0 Sigma-70, region 4 TPR_MLP1_2 PF07926.12 EPS27208.1 - 0.68 10.0 5.9 0.2 11.7 1.2 2.4 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Uso1_p115_C PF04871.13 EPS27208.1 - 1.3 9.4 4.3 0.55 10.6 1.9 1.6 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF5353 PF17304.2 EPS27209.1 - 5.4e-37 125.4 2.5 7.3e-37 125.0 2.5 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5353) GHBP PF12772.7 EPS27209.1 - 0.019 14.5 0.1 0.021 14.4 0.1 1.1 1 0 0 1 1 1 0 Growth hormone receptor binding DUF1682 PF07946.14 EPS27209.1 - 0.028 13.6 1.7 0.031 13.5 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Porin_5 PF16930.5 EPS27209.1 - 0.061 11.8 4.4 0.076 11.5 4.4 1.1 1 0 0 1 1 1 0 Putative porin Connexin PF00029.19 EPS27209.1 - 0.19 11.5 0.0 0.19 11.4 0.0 1.1 1 0 0 1 1 1 0 Connexin Defensin_propep PF00879.18 EPS27209.1 - 0.43 10.9 4.9 1.9 8.8 3.8 2.2 1 1 1 2 2 2 0 Defensin propeptide 2-oxoacid_dh PF00198.23 EPS27210.1 - 6e-74 248.4 0.1 7.5e-74 248.1 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EPS27210.1 - 4.9e-17 61.5 0.6 1.6e-16 59.9 0.6 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EPS27210.1 - 4.1e-12 46.2 1.3 1.3e-11 44.6 0.8 2.1 2 0 0 2 2 2 1 e3 binding domain SopE_GEF PF07487.13 EPS27210.1 - 0.023 14.8 0.1 0.056 13.6 0.1 1.6 1 0 0 1 1 1 0 SopE GEF domain Sec7 PF01369.20 EPS27211.1 - 4.2e-72 241.7 1.9 1.5e-71 239.9 1.9 2.1 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 EPS27211.1 - 1.3e-41 142.2 4.2 1.3e-41 142.2 4.2 2.8 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 EPS27211.1 - 5.3e-33 112.7 10.3 5e-32 109.6 0.0 5.9 7 0 0 7 7 7 1 Domain of unknown function (DUF1981) DCB PF16213.5 EPS27211.1 - 9.9e-19 67.7 3.4 8.1e-18 64.7 0.4 3.2 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 NAD_binding_7 PF13241.6 EPS27212.1 - 4.9e-32 110.5 0.1 7.2e-32 109.9 0.1 1.2 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 EPS27212.1 - 2.3e-29 100.8 0.0 3.6e-29 100.2 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 EPS27212.1 - 2.3e-15 55.7 0.1 3.8e-15 55.0 0.1 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Pyr_redox_3 PF13738.6 EPS27212.1 - 0.014 14.7 0.1 0.02 14.2 0.1 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase LSDAT_prok PF18171.1 EPS27212.1 - 0.044 13.0 0.1 0.068 12.4 0.1 1.2 1 0 0 1 1 1 0 SLOG in TRPM, prokaryote Pribosyltran_N PF13793.6 EPS27213.1 - 1.1e-43 147.8 0.0 1.2e-42 144.5 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EPS27213.1 - 1.1e-32 113.6 0.1 1.3e-27 97.1 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EPS27213.1 - 1.5e-06 27.8 0.1 0.0012 18.4 0.1 2.8 2 1 0 2 2 2 2 Phosphoribosyl transferase domain SpoVAD PF07451.11 EPS27213.1 - 0.096 11.4 0.0 0.16 10.6 0.0 1.3 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) PLDc_2 PF13091.6 EPS27217.1 - 8.2e-15 54.9 0.0 5.5e-06 26.3 0.0 3.5 3 0 0 3 3 3 3 PLD-like domain PLDc PF00614.22 EPS27217.1 - 1.9e-13 50.0 3.1 1.5e-06 28.1 0.1 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif Hom_end_hint PF05203.16 EPS27217.1 - 0.93 9.4 6.8 0.85 9.5 1.5 2.2 2 0 0 2 2 2 0 Hom_end-associated Hint RFX_DNA_binding PF02257.15 EPS27218.1 - 2.3e-27 95.4 0.2 4.5e-27 94.5 0.2 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain LigB PF02900.18 EPS27219.1 - 4e-14 52.3 0.0 5e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Fungal_trans PF04082.18 EPS27220.1 - 3.3e-16 59.1 2.7 4.8e-16 58.6 2.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS27220.1 - 3.1e-06 27.2 12.6 5.6e-06 26.4 12.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GCP_N_terminal PF17681.1 EPS27220.1 - 0.022 14.4 0.5 0.077 12.6 0.7 1.8 1 1 0 1 1 1 0 Gamma tubulin complex component N-terminal TetR_C_19 PF17924.1 EPS27220.1 - 0.084 13.5 0.2 0.18 12.4 0.2 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DUF3425 PF11905.8 EPS27221.1 - 3.4e-23 81.9 0.9 6.8e-23 81.0 0.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) PHC2_SAM_assoc PF16616.5 EPS27221.1 - 0.8 10.5 10.1 1.2 9.9 7.6 2.1 2 0 0 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 Glyco_hydro_43 PF04616.14 EPS27222.1 - 1e-66 225.2 1.6 1.4e-66 224.8 1.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 EPS27222.1 - 1.5e-33 116.2 0.0 2e-33 115.9 0.0 1.2 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain DUF5005 PF16396.5 EPS27222.1 - 0.063 12.0 0.1 4.1 6.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5005) MFS_1 PF07690.16 EPS27223.1 - 8.7e-23 80.8 57.0 3.8e-13 49.1 26.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ACOX PF01756.19 EPS27224.1 - 1.2e-46 158.5 0.1 7.3e-46 156.0 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 EPS27224.1 - 1e-27 97.2 3.0 2.4e-27 96.0 3.0 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 EPS27224.1 - 2.4e-12 46.9 0.0 8.3e-12 45.2 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EPS27224.1 - 2.6e-05 24.5 0.2 0.048 13.9 0.0 2.6 2 0 0 2 2 2 2 Acyl-CoA dehydrogenase, C-terminal domain Sugar_tr PF00083.24 EPS27225.1 - 1.1e-98 331.1 29.3 1.3e-98 330.9 29.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS27225.1 - 9.2e-26 90.6 40.2 2.2e-22 79.5 23.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EPS27225.1 - 0.00011 20.8 1.2 0.00011 20.8 1.2 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Peptidase_A4 PF01828.17 EPS27225.1 - 0.12 11.8 0.4 0.23 10.9 0.4 1.4 1 0 0 1 1 1 0 Peptidase A4 family Sugar_tr PF00083.24 EPS27226.1 - 2e-113 379.7 23.7 2.5e-113 379.3 23.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS27226.1 - 3.2e-21 75.7 26.0 1.7e-13 50.2 8.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EPS27226.1 - 0.00087 17.7 2.5 0.00087 17.7 2.5 2.4 2 1 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.16 EPS27227.1 - 4e-44 151.0 43.8 7.4e-44 150.1 40.4 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EPS27227.1 - 2.1e-10 39.7 16.3 3.1e-10 39.1 16.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EPS27227.1 - 1.3e-08 34.2 9.9 1.3e-08 34.2 9.9 3.4 4 1 0 4 4 4 2 Sugar (and other) transporter SIT PF15330.6 EPS27227.1 - 0.062 13.8 0.0 0.19 12.1 0.0 1.9 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT Sugar_tr PF00083.24 EPS27228.1 - 1.8e-88 297.4 19.5 2.1e-88 297.2 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS27228.1 - 9.4e-26 90.6 38.2 3.9e-24 85.2 31.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EPS27228.1 - 0.0063 14.9 14.3 0.27 9.5 6.2 3.0 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family UDPG_MGDP_dh_N PF03721.14 EPS27229.1 - 7e-51 172.5 0.1 3.8e-49 166.8 0.1 2.4 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.19 EPS27229.1 - 1.1e-29 102.4 0.0 3e-29 101.1 0.0 1.8 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.15 EPS27229.1 - 2.7e-21 76.0 0.0 2e-16 60.3 0.0 3.4 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_binding_2 PF03446.15 EPS27229.1 - 0.0015 18.7 0.1 0.13 12.5 0.0 2.9 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 EPS27229.1 - 0.0038 17.5 0.1 0.011 16.0 0.0 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 EPS27229.1 - 0.0095 15.6 0.0 0.028 14.1 0.0 1.8 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 EPS27229.1 - 0.047 13.9 0.1 0.36 11.1 0.0 2.5 2 1 0 2 2 2 0 TrkA-N domain 3HCDH_N PF02737.18 EPS27229.1 - 0.065 13.1 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TPT PF03151.16 EPS27231.1 - 5.8e-30 104.6 23.9 7.1e-30 104.3 23.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family DUF2730 PF10805.8 EPS27237.1 - 0.017 15.2 5.4 2 8.5 0.1 3.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) Lipid_DES PF08557.10 EPS27237.1 - 0.049 13.1 2.7 8.3 6.0 0.0 3.6 4 0 0 4 4 4 0 Sphingolipid Delta4-desaturase (DES) CPL PF08144.11 EPS27237.1 - 0.37 11.2 2.4 21 5.4 0.1 3.8 2 1 1 3 3 3 0 CPL (NUC119) domain Het-C PF07217.11 EPS27237.1 - 0.55 8.7 7.0 6.2 5.2 0.0 2.8 2 1 0 2 2 2 0 Heterokaryon incompatibility protein Het-C YfdX PF10938.8 EPS27237.1 - 2.2 8.2 9.8 1.8 8.5 1.1 4.2 3 1 1 4 4 4 0 YfdX protein SPX PF03105.19 EPS27237.1 - 4 7.3 9.3 6.4 6.6 9.3 1.3 1 0 0 1 1 1 0 SPX domain NES_C_h PF18208.1 EPS27237.1 - 4.8 7.5 6.4 28 5.0 2.7 4.1 3 1 0 3 3 3 0 Nicking enzyme C-terminal middle helical domain DASH_Duo1 PF08651.10 EPS27237.1 - 7.5 6.4 11.9 5.7 6.8 2.4 4.8 2 1 0 3 3 3 0 DASH complex subunit Duo1 EF-hand_7 PF13499.6 EPS27239.1 - 1.3e-12 48.0 0.4 4.3e-08 33.5 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 EPS27239.1 - 6.4e-10 39.2 0.0 0.00049 20.4 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_6 PF13405.6 EPS27239.1 - 2.1e-09 36.6 1.9 0.0075 16.1 0.0 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 EPS27239.1 - 4.1e-08 32.2 1.2 0.026 14.1 0.0 3.8 4 1 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 EPS27239.1 - 5.8e-07 29.3 0.2 8e-05 22.4 0.1 3.0 3 0 0 3 3 3 1 EF-hand domain pair DUF3216 PF11505.8 EPS27239.1 - 0.057 13.6 0.0 0.12 12.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3216) Fungal_trans PF04082.18 EPS27241.1 - 1.4e-66 224.3 0.0 1.9e-66 223.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EPS27241.1 - 0.0014 18.9 19.1 0.0024 18.2 2.6 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EPS27241.1 - 0.02 15.3 8.1 0.035 14.5 3.6 2.7 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 EPS27241.1 - 0.57 11.2 17.3 0.16 12.9 2.2 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger FXR_C1 PF16096.5 EPS27241.1 - 5.2 7.3 6.5 4 7.7 4.3 1.9 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 PHO4 PF01384.20 EPS27243.1 - 5.7e-109 364.2 12.6 6.7e-109 364.0 12.6 1.0 1 0 0 1 1 1 1 Phosphate transporter family Glycophorin_A PF01102.18 EPS27243.1 - 0.0016 18.7 0.0 0.0072 16.5 0.0 2.1 2 0 0 2 2 2 1 Glycophorin A Xpo1 PF08389.12 EPS27244.1 - 1.7e-26 93.1 0.1 3.2e-25 88.9 0.0 3.2 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 EPS27244.1 - 9.5e-06 25.4 0.0 5e-05 23.1 0.0 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 EPS27244.1 - 0.036 14.5 0.1 0.61 10.5 0.0 2.9 2 0 0 2 2 2 0 HEAT repeats TAF1_subA PF14929.6 EPS27244.1 - 0.21 10.9 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 TAF RNA Polymerase I subunit A HEAT PF02985.22 EPS27244.1 - 0.31 11.4 2.3 7.7 7.1 0.0 4.6 5 0 0 5 5 5 0 HEAT repeat Pardaxin PF07425.11 EPS27244.1 - 2 8.1 3.7 2.2 7.9 0.2 2.6 2 0 0 2 2 2 0 Pardaxin LSM PF01423.22 EPS27245.1 - 2.2e-13 49.7 0.0 2.5e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EPS27245.1 - 0.0015 18.1 0.0 0.0022 17.6 0.0 1.3 1 0 0 1 1 1 1 Hfq protein 5-FTHF_cyc-lig PF01812.20 EPS27246.1 - 1.3e-38 132.7 0.0 1.6e-38 132.5 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family ATP-grasp_6 PF18419.1 EPS27246.1 - 0.14 11.8 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp-like domain Rot1 PF10681.9 EPS27247.1 - 3.7e-92 307.6 0.0 4.2e-92 307.4 0.0 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal YqeY PF09424.10 EPS27248.1 - 1e-22 80.7 6.1 1.2e-22 80.5 6.1 1.0 1 0 0 1 1 1 1 Yqey-like protein CM_2 PF01817.21 EPS27248.1 - 0.48 10.8 5.1 1 9.7 4.9 1.7 1 1 0 1 1 1 0 Chorismate mutase type II Nucleoporin_N PF08801.11 EPS27249.1 - 2.1e-93 313.4 0.1 3.6e-93 312.7 0.1 1.4 1 0 0 1 1 1 1 Nup133 N terminal like Nucleoporin_C PF03177.14 EPS27249.1 - 2.1e-51 175.4 2.6 4.2e-51 174.4 0.9 1.9 2 0 0 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal ADSL_C PF10397.9 EPS27249.1 - 0.13 12.9 0.4 3 8.4 0.1 2.9 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminus TFIIA PF03153.13 EPS27249.1 - 5.7 6.8 12.0 14 5.5 12.0 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TauD PF02668.16 EPS27250.1 - 1.6e-48 165.8 0.2 2.1e-48 165.5 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family UPF0302 PF08864.10 EPS27250.1 - 0.007 16.4 0.0 0.015 15.4 0.0 1.6 1 0 0 1 1 1 1 UPF0302 domain DUF2781 PF10914.8 EPS27252.1 - 1.5e-40 139.0 11.7 1.7e-40 138.8 11.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) LapA_dom PF06305.11 EPS27252.1 - 3.2 7.6 4.8 9.3 6.2 0.0 2.7 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Asp_protease PF09668.10 EPS27253.1 - 3.6e-60 201.2 0.1 5.5e-60 200.6 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EPS27253.1 - 1.3e-21 76.9 0.0 2.8e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EPS27253.1 - 1.1e-10 42.0 0.0 2.7e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.23 EPS27253.1 - 4.4e-07 29.6 0.0 8e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 EPS27253.1 - 2.6e-06 27.2 0.5 1e-05 25.3 0.0 2.1 2 0 0 2 2 2 1 UBA/TS-N domain RVP_2 PF08284.11 EPS27253.1 - 0.0021 17.8 0.0 0.004 16.9 0.0 1.4 1 1 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.20 EPS27253.1 - 0.0056 17.0 0.0 0.027 14.8 0.0 2.2 2 1 0 2 2 2 1 Retroviral aspartyl protease Rad60-SLD PF11976.8 EPS27253.1 - 0.014 15.2 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like RuvA_C PF07499.13 EPS27253.1 - 0.017 15.6 0.7 0.32 11.5 0.0 2.8 3 0 0 3 3 3 0 RuvA, C-terminal domain UBA_4 PF14555.6 EPS27253.1 - 0.034 14.0 0.1 0.08 12.8 0.1 1.6 1 0 0 1 1 1 0 UBA-like domain NAD_binding_7 PF13241.6 EPS27253.1 - 0.17 12.4 0.1 0.96 9.9 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding Pan3_PK PF18101.1 EPS27254.1 - 0.06 13.3 0.0 0.072 13.1 0.0 1.1 1 0 0 1 1 1 0 Pan3 Pseudokinase domain zf-RING_2 PF13639.6 EPS27255.1 - 3.1e-12 46.6 2.9 5.3e-12 45.9 2.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EPS27255.1 - 2.3e-11 43.2 2.6 4.4e-11 42.3 2.6 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EPS27255.1 - 5.4e-09 35.7 2.7 9.7e-09 34.9 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPS27255.1 - 5.3e-08 32.6 1.5 9.1e-08 31.9 1.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPS27255.1 - 3.5e-06 26.9 2.7 6.6e-06 26.1 2.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 EPS27255.1 - 6.1e-06 25.8 3.0 1.1e-05 25.0 3.0 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 EPS27255.1 - 8.5e-06 26.0 5.9 0.00011 22.4 5.9 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EPS27255.1 - 2.3e-05 24.2 1.5 4.1e-05 23.4 1.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EPS27255.1 - 0.00075 19.3 2.8 0.0014 18.5 2.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Vps39_2 PF10367.9 EPS27255.1 - 0.0017 18.8 0.3 0.0029 18.0 0.3 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-C3HC4_3 PF13920.6 EPS27255.1 - 0.0018 18.1 1.4 0.0029 17.4 1.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 EPS27255.1 - 0.0019 18.5 2.1 0.0037 17.6 2.1 1.5 1 0 0 1 1 1 1 RING-like domain zf-ANAPC11 PF12861.7 EPS27255.1 - 0.014 15.4 2.7 0.047 13.8 2.7 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF4711 PF15829.5 EPS27255.1 - 0.017 15.1 0.2 0.031 14.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4711) FANCL_C PF11793.8 EPS27255.1 - 0.017 15.3 2.1 0.041 14.1 2.1 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain Zf_RING PF16744.5 EPS27255.1 - 0.031 14.4 2.2 0.066 13.3 2.2 1.5 1 0 0 1 1 1 0 KIAA1045 RING finger RINGv PF12906.7 EPS27255.1 - 0.054 13.6 2.6 0.17 12.0 2.7 1.9 1 1 0 1 1 1 0 RING-variant domain PHD PF00628.29 EPS27255.1 - 0.12 12.2 2.1 0.21 11.5 2.1 1.4 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.6 EPS27255.1 - 0.23 11.6 2.1 0.96 9.7 2.1 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF2175 PF09943.9 EPS27255.1 - 0.26 11.6 2.0 0.58 10.5 1.6 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) DUF3754 PF12576.8 EPS27257.1 - 6.1 6.8 5.4 41 4.1 2.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3754) Peptidase_M3 PF01432.20 EPS27259.1 - 1.2e-161 539.1 0.0 1.7e-161 538.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 SUV3_C PF12513.8 EPS27259.1 - 0.14 12.1 0.0 0.38 10.7 0.0 1.8 1 0 0 1 1 1 0 Mitochondrial degradasome RNA helicase subunit C terminal AMP-binding PF00501.28 EPS27260.1 - 9.7e-70 235.3 0.0 1.3e-69 234.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EPS27260.1 - 7.6e-56 189.1 0.0 1.3e-55 188.4 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding_C PF13193.6 EPS27260.1 - 4.2e-14 53.3 0.4 1.3e-13 51.8 0.4 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.21 EPS27260.1 - 2.4e-13 50.1 0.0 4.7e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EPS27260.1 - 4.4e-08 33.3 0.1 8.6e-08 32.4 0.1 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 EPS27260.1 - 1.3e-07 30.9 0.0 3.1e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EPS27260.1 - 9.8e-05 21.9 0.0 0.00023 20.7 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 EPS27260.1 - 0.004 17.6 0.0 0.0091 16.4 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 EPS27260.1 - 0.025 13.7 0.0 0.052 12.7 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Aminotran_1_2 PF00155.21 EPS27261.1 - 1.2e-30 106.9 0.0 1.5e-30 106.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EPS27261.1 - 0.004 15.8 0.0 0.0065 15.0 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme FA_desaturase PF00487.24 EPS27262.1 - 1.6e-18 67.5 16.9 1.6e-18 67.5 16.9 1.5 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EPS27262.1 - 4.7e-17 61.9 0.2 1.2e-16 60.6 0.1 1.7 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain TT1725 PF18324.1 EPS27263.1 - 0.058 13.5 0.0 0.066 13.3 0.0 1.1 1 0 0 1 1 1 0 Hypothetical protein TT1725 DNA_pol_B_palm PF14792.6 EPS27263.1 - 0.096 12.9 0.0 0.13 12.5 0.0 1.4 1 1 0 1 1 1 0 DNA polymerase beta palm Xan_ur_permease PF00860.20 EPS27264.1 - 6.5e-65 219.3 35.1 6e-64 216.2 35.1 2.0 1 1 0 1 1 1 1 Permease family AcrZ PF10766.9 EPS27264.1 - 0.53 9.9 4.4 0.27 10.8 0.2 2.5 2 0 0 2 2 2 0 Multidrug efflux pump-associated protein AcrZ MOSC PF03473.17 EPS27265.1 - 1.1e-22 80.5 0.0 2.1e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 EPS27265.1 - 6.9e-10 38.9 0.0 1.2e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Rad51 PF08423.11 EPS27266.1 - 3.2e-14 52.8 0.0 4.3e-13 49.1 0.0 2.1 1 1 0 1 1 1 1 Rad51 RecA PF00154.21 EPS27266.1 - 3e-07 30.2 0.0 1e-06 28.4 0.0 1.9 1 1 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 EPS27266.1 - 4.3e-07 29.5 0.0 1.3e-06 27.9 0.0 1.7 2 0 0 2 2 2 1 KaiC AAA_25 PF13481.6 EPS27266.1 - 1.8e-05 24.4 0.0 0.00088 18.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EPS27266.1 - 6.4e-05 22.8 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA PF00004.29 EPS27266.1 - 0.0019 18.6 0.0 0.0046 17.4 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EPS27266.1 - 0.0023 17.7 0.0 0.0054 16.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EPS27266.1 - 0.0089 16.4 0.1 0.024 15.0 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain DnaB_C PF03796.15 EPS27266.1 - 0.023 14.0 0.0 0.1 11.9 0.0 1.9 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain CbiA PF01656.23 EPS27266.1 - 0.043 13.9 0.0 0.06 13.4 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 EPS27266.1 - 0.07 13.3 0.0 0.25 11.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EPS27266.1 - 0.079 13.2 0.1 0.2 11.9 0.0 1.8 2 1 0 2 2 2 0 AAA domain CLP1_P PF16575.5 EPS27266.1 - 0.079 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop PhoH PF02562.16 EPS27266.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.6 EPS27266.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zot PF05707.12 EPS27266.1 - 0.18 11.4 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) ATPase_2 PF01637.18 EPS27266.1 - 0.2 11.6 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Bunya_nucleocap PF00952.17 EPS27268.1 - 0.02 14.9 0.0 0.027 14.5 0.0 1.1 1 0 0 1 1 1 0 Bunyavirus nucleocapsid (N) protein Proteasome PF00227.26 EPS27269.1 - 1.2e-56 191.2 0.0 6.9e-32 110.5 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.9 EPS27269.1 - 8.7e-11 41.3 0.1 3.1e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RINGv PF12906.7 EPS27270.1 - 4.6e-09 36.3 3.7 1.2e-08 35.0 1.0 2.3 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.6 EPS27270.1 - 0.29 11.5 4.7 0.85 10.0 1.6 2.2 2 0 0 2 2 2 0 Ring finger domain PHD_4 PF16866.5 EPS27270.1 - 2 8.6 4.6 6 7.0 2.7 2.3 1 1 1 2 2 2 0 PHD-finger Amidohydro_2 PF04909.14 EPS27272.1 - 6e-40 137.8 0.4 7.3e-40 137.6 0.4 1.1 1 0 0 1 1 1 1 Amidohydrolase Acid_PPase PF12689.7 EPS27272.1 - 0.039 13.8 0.0 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 Acid Phosphatase Sugar_tr PF00083.24 EPS27273.1 - 1.7e-88 297.5 31.1 2.1e-88 297.2 31.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS27273.1 - 1.7e-12 46.9 33.8 1.7e-12 46.9 33.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily N_NLPC_P60 PF12912.7 EPS27273.1 - 0.097 13.0 0.0 0.23 11.8 0.0 1.5 1 0 0 1 1 1 0 NLPC_P60 stabilising domain, N term CTP_synth_N PF06418.14 EPS27274.1 - 3.8e-121 403.4 0.6 4.9e-121 403.1 0.6 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 EPS27274.1 - 4.9e-53 179.7 0.0 7.9e-53 179.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EPS27274.1 - 1.6e-05 24.7 0.3 6.8e-05 22.7 0.3 2.1 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.23 EPS27274.1 - 0.0057 16.7 0.0 0.011 15.8 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Ank_2 PF12796.7 EPS27275.1 - 2.6e-40 136.9 0.2 2.8e-14 53.5 0.0 7.0 4 2 2 7 7 7 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPS27275.1 - 1.2e-29 102.3 2.0 2.5e-10 40.7 0.0 8.6 8 1 1 9 9 9 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPS27275.1 - 6.5e-26 87.6 3.8 0.06 13.9 0.0 11.3 12 0 0 12 12 12 7 Ankyrin repeat Ank_5 PF13857.6 EPS27275.1 - 7.3e-23 80.3 6.7 0.00034 20.8 0.0 8.8 7 1 3 10 10 10 6 Ankyrin repeats (many copies) Ank PF00023.30 EPS27275.1 - 6e-22 77.1 4.4 0.0016 18.8 0.0 9.6 9 1 0 9 9 9 5 Ankyrin repeat F-box-like PF12937.7 EPS27275.1 - 2.3e-05 24.2 0.4 5.9e-05 22.9 0.4 1.7 1 0 0 1 1 1 1 F-box-like Pectate_lyase_3 PF12708.7 EPS27276.1 - 9.4e-97 323.0 8.9 1.1e-82 277.1 0.7 3.2 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EPS27276.1 - 5.8e-05 22.7 1.1 0.035 13.8 0.1 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase DNase_NucA_NucB PF14040.6 EPS27277.1 - 1.6e-06 28.5 0.3 0.036 14.5 0.0 2.6 3 0 0 3 3 3 2 Deoxyribonuclease NucA/NucB F-box-like PF12937.7 EPS27278.1 - 5.4e-08 32.6 0.5 1.3e-07 31.4 0.5 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EPS27278.1 - 1.9e-06 27.6 0.5 3.6e-06 26.7 0.5 1.4 1 0 0 1 1 1 1 F-box domain LIN52 PF10044.9 EPS27278.1 - 0.0016 19.1 0.0 0.0034 18.0 0.0 1.5 1 0 0 1 1 1 1 Retinal tissue protein GFA PF04828.14 EPS27284.1 - 5.3e-23 81.2 0.0 7e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Pkinase PF00069.25 EPS27285.1 - 1.2e-06 28.1 0.0 1.4e-06 27.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain RRM_1 PF00076.22 EPS27286.1 - 3.2e-19 68.5 0.0 2.9e-14 52.7 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EPS27286.1 - 0.026 14.4 0.0 0.053 13.4 0.0 1.6 1 0 0 1 1 1 0 Occluded RNA-recognition motif RRM_7 PF16367.5 EPS27286.1 - 0.03 14.4 0.0 1.9 8.7 0.0 2.9 2 1 1 3 3 3 0 RNA recognition motif Laminin_G_1 PF00054.23 EPS27286.1 - 0.083 13.1 0.0 1.1 9.5 0.0 2.1 2 0 0 2 2 2 0 Laminin G domain Cyc-maltodext_N PF09087.11 EPS27286.1 - 0.11 12.8 0.0 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 Cyclomaltodextrinase, N-terminal 6PF2K PF01591.18 EPS27287.1 - 1.2e-77 260.2 0.1 1.6e-77 259.8 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EPS27287.1 - 4.8e-41 140.6 0.0 8.6e-41 139.8 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EPS27287.1 - 0.00091 19.4 0.0 0.0022 18.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EPS27287.1 - 0.00099 18.6 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Vps39_2 PF10367.9 EPS27288.1 - 1.1e-29 103.1 0.0 4.8e-29 101.0 0.0 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 EPS27288.1 - 2e-28 98.8 0.0 8.6e-28 96.8 0.0 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.22 EPS27288.1 - 5.5e-15 55.7 0.0 1.1e-14 54.8 0.0 1.4 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.20 EPS27288.1 - 2.9e-07 30.4 3.2 1.1e-05 25.3 0.7 3.0 3 0 0 3 3 3 1 Region in Clathrin and VPS TPR_1 PF00515.28 EPS27288.1 - 0.018 14.9 0.5 1.2 9.1 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Trypan_PARP PF05887.11 EPS27288.1 - 0.057 13.4 1.7 0.12 12.4 1.7 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CPSF_A PF03178.15 EPS27288.1 - 0.063 12.6 0.0 7.8 5.7 0.0 2.2 2 0 0 2 2 2 0 CPSF A subunit region TPR_12 PF13424.6 EPS27288.1 - 0.6 10.4 6.2 0.45 10.8 0.5 3.5 4 1 1 5 5 5 0 Tetratricopeptide repeat Gon7 PF08738.10 EPS27289.1 - 5.9e-12 45.6 4.4 5.7e-11 42.5 1.1 2.0 1 1 1 2 2 2 2 Gon7 family UME PF08064.13 EPS27289.1 - 0.11 12.5 0.1 0.13 12.2 0.1 1.1 1 0 0 1 1 1 0 UME (NUC010) domain HbrB PF08539.11 EPS27290.1 - 4.1e-46 157.1 0.5 1.2e-45 155.6 0.1 2.1 2 0 0 2 2 2 1 HbrB-like CFEM PF05730.11 EPS27291.1 - 1.5e-05 24.9 3.4 1.5e-05 24.9 3.4 2.7 2 0 0 2 2 2 1 CFEM domain Tme5_EGF_like PF09064.10 EPS27291.1 - 0.022 14.7 3.6 0.12 12.3 3.6 2.3 1 0 0 1 1 1 0 Thrombomodulin like fifth domain, EGF-like TIL PF01826.17 EPS27291.1 - 0.37 11.1 3.2 2.2 8.6 3.2 2.4 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain Fungal_trans PF04082.18 EPS27292.1 - 4.6e-12 45.5 0.1 7e-12 44.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS27292.1 - 4.8e-09 36.2 10.2 7.8e-09 35.5 10.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhyH PF05721.13 EPS27293.1 - 4.2e-06 27.2 0.1 9.6e-06 26.0 0.1 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 EPS27293.1 - 6.5e-05 21.9 0.0 0.77 8.4 0.1 3.0 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_5 PF13759.6 EPS27293.1 - 0.0014 19.0 0.0 0.0027 18.1 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.6 EPS27293.1 - 0.033 15.1 0.0 0.066 14.1 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily NmrA PF05368.13 EPS27296.1 - 1.3e-17 64.1 0.0 1.6e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPS27296.1 - 3.7e-17 62.8 0.0 5.9e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding TrkA_N PF02254.18 EPS27296.1 - 0.0068 16.7 0.0 0.015 15.6 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Methyltransf_25 PF13649.6 EPS27296.1 - 0.029 15.1 0.1 0.27 12.0 0.0 2.5 2 1 1 3 3 3 0 Methyltransferase domain Methyltransf_11 PF08241.12 EPS27296.1 - 0.033 14.8 0.0 0.15 12.7 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Epimerase PF01370.21 EPS27296.1 - 0.067 12.6 0.0 0.36 10.2 0.0 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Methyltransf_12 PF08242.12 EPS27296.1 - 0.13 13.0 0.0 0.38 11.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain TamB PF04357.13 EPS27297.1 - 0.033 13.4 0.0 0.038 13.2 0.0 1.0 1 0 0 1 1 1 0 TamB, inner membrane protein subunit of TAM complex MFS_1 PF07690.16 EPS27298.1 - 3.8e-22 78.7 21.8 3.8e-22 78.7 21.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS27298.1 - 6e-14 51.8 2.9 6e-14 51.8 2.9 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.20 EPS27298.1 - 0.00032 19.1 2.6 0.017 13.5 0.3 2.4 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Peptidase_S15 PF02129.18 EPS27299.1 - 5.7e-46 157.3 0.2 8.5e-42 143.6 0.0 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 EPS27299.1 - 4.9e-39 134.6 0.0 6.4e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain ThiF PF00899.21 EPS27301.1 - 4.2e-27 95.1 0.0 5.6e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 ThiF family Ytp1 PF10355.9 EPS27302.1 - 8.2e-69 231.9 24.1 8.2e-69 231.9 24.1 2.3 2 1 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 EPS27302.1 - 6.6e-32 109.4 1.8 6.6e-32 109.4 1.8 3.4 4 1 1 5 5 5 2 Domain of unknown function (DUF2427) Swi5 PF07061.11 EPS27303.1 - 3.2e-33 113.7 0.3 3.8e-33 113.4 0.3 1.1 1 0 0 1 1 1 1 Swi5 TSC22 PF01166.18 EPS27303.1 - 0.0065 16.7 0.4 0.012 15.9 0.3 1.6 1 1 0 1 1 1 1 TSC-22/dip/bun family DUF2115 PF09888.9 EPS27303.1 - 0.011 16.3 0.0 0.013 16.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) FapA PF03961.13 EPS27303.1 - 0.012 14.2 0.1 0.013 14.1 0.1 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A SOGA PF11365.8 EPS27303.1 - 0.014 16.5 0.2 0.017 16.2 0.2 1.3 1 0 0 1 1 1 0 Protein SOGA Atg14 PF10186.9 EPS27303.1 - 0.026 13.6 0.4 0.03 13.4 0.4 1.0 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 APG6_N PF17675.1 EPS27303.1 - 0.03 14.9 1.5 0.04 14.4 1.5 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Cep57_MT_bd PF06657.13 EPS27303.1 - 0.032 14.7 0.8 0.05 14.1 0.8 1.3 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 DivIC PF04977.15 EPS27303.1 - 0.038 13.8 4.1 0.11 12.3 2.9 1.9 1 1 1 2 2 2 0 Septum formation initiator Prefoldin_2 PF01920.20 EPS27303.1 - 0.041 13.8 0.7 0.15 12.0 0.5 1.8 1 1 1 2 2 2 0 Prefoldin subunit ABC_tran_CTD PF16326.5 EPS27303.1 - 0.057 13.7 1.2 0.086 13.1 1.2 1.3 1 0 0 1 1 1 0 ABC transporter C-terminal domain DUF1640 PF07798.11 EPS27303.1 - 0.075 13.1 0.2 0.086 12.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) YabA PF06156.13 EPS27303.1 - 0.12 13.0 0.3 0.16 12.6 0.3 1.2 1 0 0 1 1 1 0 Initiation control protein YabA ABC_membrane PF00664.23 EPS27304.1 - 2.5e-103 345.5 33.1 1.3e-54 185.7 11.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EPS27304.1 - 4e-68 228.2 0.0 1.1e-32 113.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EPS27304.1 - 7e-14 51.8 0.0 0.00058 19.4 0.0 4.0 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EPS27304.1 - 7.6e-08 32.9 2.6 0.007 16.8 0.1 3.5 2 2 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EPS27304.1 - 2.4e-07 30.4 0.3 0.0027 17.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.29 EPS27304.1 - 4.4e-07 30.4 0.1 4.9 7.6 0.0 4.5 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EPS27304.1 - 2.8e-06 27.6 0.3 0.057 13.7 0.0 3.7 4 0 0 4 4 4 2 AAA domain AAA_21 PF13304.6 EPS27304.1 - 4.2e-06 26.8 0.5 0.0099 15.7 0.0 3.4 4 0 0 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 EPS27304.1 - 5.2e-06 25.5 0.1 0.013 14.3 0.0 2.4 2 0 0 2 2 2 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 EPS27304.1 - 1.1e-05 25.4 0.0 0.16 11.8 0.0 2.9 3 0 0 3 3 2 2 RsgA GTPase AAA_30 PF13604.6 EPS27304.1 - 4.3e-05 23.3 3.5 0.61 9.8 0.0 4.2 5 0 0 5 5 5 2 AAA domain Rad17 PF03215.15 EPS27304.1 - 0.0002 21.3 0.1 0.03 14.3 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_25 PF13481.6 EPS27304.1 - 0.00063 19.4 0.0 0.48 10.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EPS27304.1 - 0.0012 19.4 0.0 1.3 9.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EPS27304.1 - 0.0014 18.6 0.4 3.9 7.5 0.0 3.2 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 EPS27304.1 - 0.0015 18.3 0.0 1.1 8.8 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.6 EPS27304.1 - 0.0018 18.4 0.0 2.2 8.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 EPS27304.1 - 0.0022 18.5 0.0 1.2 9.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EPS27304.1 - 0.0059 16.1 0.0 2 7.9 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region SbcCD_C PF13558.6 EPS27304.1 - 0.0061 16.8 4.5 1.9 8.7 0.3 4.0 3 2 0 3 3 2 1 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 EPS27304.1 - 0.012 15.8 0.3 2.4 8.2 0.1 2.7 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_24 PF13479.6 EPS27304.1 - 0.013 15.2 0.3 3.3 7.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 EPS27304.1 - 0.014 15.1 0.3 1.7 8.2 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 EPS27304.1 - 0.024 13.9 0.0 8 5.7 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 EPS27304.1 - 0.025 14.9 0.1 5.5 7.4 0.0 3.1 3 0 0 3 3 2 0 RNA helicase AAA_28 PF13521.6 EPS27304.1 - 0.032 14.5 0.6 1.3 9.2 0.1 2.6 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 EPS27304.1 - 0.045 13.5 0.1 2.6 7.8 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Cytidylate_kin PF02224.18 EPS27304.1 - 0.049 13.4 0.0 4.4 7.0 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase APS_kinase PF01583.20 EPS27304.1 - 0.072 13.0 0.1 3.3 7.6 0.0 2.6 2 0 0 2 2 2 0 Adenylylsulphate kinase G-alpha PF00503.20 EPS27304.1 - 0.079 12.1 0.0 12 4.9 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit AAA_17 PF13207.6 EPS27304.1 - 0.1 13.0 0.8 30 5.0 0.2 3.5 4 0 0 4 4 2 0 AAA domain Cuticle_1 PF08140.11 EPS27304.1 - 0.8 9.8 2.7 64 3.7 0.0 3.7 3 0 0 3 3 3 0 Crustacean cuticle protein repeat Ribosomal_L39 PF00832.20 EPS27305.1 - 6.2e-22 77.0 9.4 7.3e-22 76.7 9.4 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Skp1 PF01466.19 EPS27306.1 - 2.5e-28 98.0 0.5 4.6e-28 97.1 0.5 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 EPS27306.1 - 6.1e-23 80.8 0.2 1.5e-22 79.5 0.1 1.7 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Glyco_transf_22 PF03901.17 EPS27307.1 - 4.9e-66 223.7 16.6 6.3e-66 223.3 16.6 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family XPC-binding PF09280.11 EPS27308.1 - 1e-22 79.6 14.0 1.8e-22 78.8 14.0 1.4 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.31 EPS27308.1 - 4.6e-22 77.5 4.3 4.3e-13 48.9 0.2 2.5 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 EPS27308.1 - 4.2e-16 58.5 0.1 8.1e-16 57.5 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EPS27308.1 - 3.4e-06 26.8 0.6 6.8e-06 25.8 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 EPS27308.1 - 0.00061 19.9 0.0 0.00061 19.9 0.0 1.9 2 0 0 2 2 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EPS27308.1 - 0.00063 20.1 0.1 0.0014 19.0 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain UBA_3 PF09288.10 EPS27308.1 - 0.0071 16.1 0.0 2.4 8.1 0.0 2.4 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain Ubiquitin_4 PF18036.1 EPS27308.1 - 0.04 14.0 0.2 1.4 9.0 0.0 2.5 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 EPS27308.1 - 0.062 13.9 0.0 0.25 11.9 0.0 1.9 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain CCDC53 PF10152.9 EPS27308.1 - 1.3 9.5 7.0 10 6.5 0.3 2.5 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Calpain_inhib PF00748.19 EPS27308.1 - 5.2 7.6 11.6 30 5.1 0.0 3.3 3 0 0 3 3 3 0 Calpain inhibitor DUF5320 PF17253.2 EPS27310.1 - 0.59 11.2 20.6 0.92 10.6 13.5 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5320) eIF-6 PF01912.18 EPS27311.1 - 1.5e-81 272.5 0.7 2e-81 272.1 0.7 1.1 1 0 0 1 1 1 1 eIF-6 family SRI PF08236.11 EPS27312.1 - 1.7e-18 66.6 13.6 4.3e-18 65.3 13.6 1.7 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.28 EPS27312.1 - 4.9e-16 59.6 0.2 4.9e-16 59.6 0.2 3.4 2 2 0 2 2 2 1 SET domain AWS PF17907.1 EPS27312.1 - 1.9e-10 40.6 8.3 1.9e-10 40.6 8.3 2.0 2 0 0 2 2 2 1 AWS domain Med26 PF08711.11 EPS27312.1 - 3.7e-05 23.6 1.5 6.4e-05 22.9 0.1 2.2 2 0 0 2 2 2 1 TFIIS helical bundle-like domain WW PF00397.26 EPS27312.1 - 4.6e-05 23.4 0.9 0.00012 22.1 0.9 1.8 1 0 0 1 1 1 1 WW domain UL42 PF17638.2 EPS27312.1 - 6.1 6.8 8.0 18 5.3 8.0 1.8 1 0 0 1 1 1 0 HCMV UL42 AT_hook PF02178.19 EPS27314.1 - 0.0034 17.1 1.3 0.02 14.7 1.3 2.5 1 0 0 1 1 1 1 AT hook motif Pkinase PF00069.25 EPS27315.1 - 8.7e-55 185.9 0.0 7.1e-50 169.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EPS27315.1 - 4.7e-35 121.1 0.1 1.3e-33 116.4 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EPS27315.1 - 3.2e-06 26.7 0.0 1.2e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EPS27315.1 - 0.00037 20.5 0.1 0.0012 18.9 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EPS27315.1 - 0.014 14.2 0.0 0.047 12.5 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase DUF1168 PF06658.12 EPS27315.1 - 0.31 10.8 2.3 1.5 8.7 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1168) UPF0561 PF10573.9 EPS27315.1 - 5.2 7.2 13.1 3.9 7.6 1.1 3.1 3 0 0 3 3 3 0 Uncharacterised protein family UPF0561 Sybindin PF04099.12 EPS27316.1 - 4.3e-26 91.6 0.0 5.3e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 EPS27316.1 - 0.0018 18.4 0.2 0.0025 17.9 0.2 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Pkinase PF00069.25 EPS27319.1 - 4.1e-48 164.0 0.0 6.2e-48 163.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS27319.1 - 8e-27 94.1 0.0 1.2e-26 93.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EPS27319.1 - 0.006 16.0 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EPS27319.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.5 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 EPS27319.1 - 0.023 14.6 0.7 1.9 8.4 0.0 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family EndoU_bacteria PF14436.6 EPS27320.1 - 0.043 14.2 1.2 0.045 14.1 1.2 1.1 1 0 0 1 1 1 0 Bacterial EndoU nuclease DUF3432 PF11914.8 EPS27324.1 - 3 8.2 60.6 0.47 10.7 13.4 5.0 1 1 4 5 5 5 0 Domain of unknown function (DUF3432) BAR PF03114.18 EPS27325.1 - 8.2e-64 215.5 3.3 1e-63 215.2 3.3 1.1 1 0 0 1 1 1 1 BAR domain CP12 PF02672.15 EPS27325.1 - 0.019 15.7 0.0 0.12 13.2 0.0 2.4 2 2 1 3 3 3 0 CP12 domain DUF2884 PF11101.8 EPS27325.1 - 0.15 11.5 2.1 2.5 7.6 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) Jnk-SapK_ap_N PF09744.9 EPS27325.1 - 0.35 11.1 8.2 1 9.6 1.6 3.0 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 CDPS PF16715.5 EPS27325.1 - 0.51 10.0 5.2 0.12 12.0 0.7 1.9 2 0 0 2 2 2 0 Cyclodipeptide synthase SVIP PF15811.5 EPS27325.1 - 9.9 6.7 8.0 0.54 10.7 1.4 2.2 2 1 0 2 2 2 0 Small VCP/p97-interacting protein Pept_tRNA_hydro PF01195.19 EPS27326.1 - 3.6e-21 75.9 0.0 3.5e-13 49.9 0.0 2.3 2 1 0 2 2 2 2 Peptidyl-tRNA hydrolase Brix PF04427.18 EPS27327.1 - 7.5e-27 94.7 0.0 1.5e-26 93.7 0.0 1.4 1 0 0 1 1 1 1 Brix domain BUD22 PF09073.10 EPS27327.1 - 0.033 13.5 21.5 0.046 13.1 21.5 1.1 1 0 0 1 1 1 0 BUD22 Sporozoite_P67 PF05642.11 EPS27327.1 - 3.2 5.7 7.3 4.5 5.2 7.3 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Hid1 PF12722.7 EPS27327.1 - 5.6 5.0 7.2 6.4 4.8 7.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nop14 PF04147.12 EPS27327.1 - 9 4.4 21.7 12 3.9 21.7 1.1 1 0 0 1 1 1 0 Nop14-like family HGTP_anticodon PF03129.20 EPS27328.1 - 1.5e-21 76.3 0.0 7e-21 74.2 0.0 2.2 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EPS27328.1 - 1.8e-06 28.0 0.1 6.8e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Pkinase PF00069.25 EPS27329.1 - 2.5e-67 227.0 0.7 2.4e-66 223.8 0.7 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS27329.1 - 2e-51 174.8 0.1 3.6e-51 173.9 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 EPS27329.1 - 9.6e-25 86.7 0.2 3.8e-24 84.8 0.0 2.1 2 0 0 2 2 2 1 P21-Rho-binding domain PH_11 PF15413.6 EPS27329.1 - 5.2e-14 52.5 0.3 1.6e-13 51.0 0.3 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain Kinase-like PF14531.6 EPS27329.1 - 5.9e-06 25.8 0.0 9.9e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EPS27329.1 - 4e-05 22.6 0.0 4e-05 22.6 0.0 2.3 3 0 0 3 3 3 1 Fungal protein kinase PH PF00169.29 EPS27329.1 - 5.1e-05 23.7 0.1 0.00012 22.5 0.1 1.7 1 0 0 1 1 1 1 PH domain Haspin_kinase PF12330.8 EPS27329.1 - 0.0015 17.6 0.1 0.0015 17.6 0.1 1.7 2 0 0 2 2 2 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 EPS27329.1 - 0.02 13.9 0.1 0.034 13.2 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.23 EPS27329.1 - 0.46 10.4 4.0 0.22 11.4 0.4 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family Acyltransferase PF01553.21 EPS27331.1 - 1.5e-27 95.8 0.0 2.2e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 EPS27331.1 - 3.1e-14 52.8 0.0 6.6e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase C-terminus TPR_2 PF07719.17 EPS27332.1 - 9.6e-29 97.2 27.4 0.0011 18.9 0.1 13.0 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_1 PF00515.28 EPS27332.1 - 3.2e-21 74.2 24.5 0.0003 20.5 0.1 11.8 13 0 0 13 13 13 5 Tetratricopeptide repeat TPR_19 PF14559.6 EPS27332.1 - 4.3e-18 65.6 33.8 3e-06 27.7 0.3 10.7 10 3 3 13 13 12 6 Tetratricopeptide repeat TPR_8 PF13181.6 EPS27332.1 - 5e-12 45.0 23.0 0.0059 16.7 0.1 10.9 12 0 0 12 12 11 3 Tetratricopeptide repeat TPR_12 PF13424.6 EPS27332.1 - 1e-09 38.5 34.3 0.0066 16.7 0.2 10.3 8 2 3 11 11 10 3 Tetratricopeptide repeat TPR_16 PF13432.6 EPS27332.1 - 1.9e-09 38.0 40.8 0.023 15.3 0.0 10.3 10 1 1 12 12 10 5 Tetratricopeptide repeat TPR_7 PF13176.6 EPS27332.1 - 1.3e-08 34.3 18.5 0.00054 19.8 0.4 8.4 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 EPS27332.1 - 6.8e-08 32.7 25.5 0.059 14.0 0.0 11.7 12 0 0 12 12 11 2 Tetratricopeptide repeat TPR_14 PF13428.6 EPS27332.1 - 2.9e-07 30.8 50.3 0.65 11.0 0.1 13.2 12 1 3 15 15 12 4 Tetratricopeptide repeat TPR_11 PF13414.6 EPS27332.1 - 8.3e-07 28.6 20.5 0.37 10.5 0.0 8.3 7 2 2 9 9 9 4 TPR repeat TPR_17 PF13431.6 EPS27332.1 - 0.00018 21.7 15.9 0.83 10.2 0.0 9.5 13 0 0 13 13 10 1 Tetratricopeptide repeat GGDEF_2 PF17853.1 EPS27332.1 - 0.012 15.9 0.1 0.097 12.9 0.1 2.7 2 0 0 2 2 2 0 GGDEF-like domain TPR_10 PF13374.6 EPS27332.1 - 0.017 15.0 37.8 0.3 11.0 0.4 9.8 11 0 0 11 11 11 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EPS27332.1 - 0.026 14.8 17.2 0.19 12.0 0.2 6.8 7 0 0 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 EPS27332.1 - 1.6 8.8 8.0 22 5.1 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF1925 PF09094.11 EPS27334.1 - 0.16 12.3 3.7 0.3 11.4 3.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1925) E_Pc_C PF06752.12 EPS27334.1 - 5.9 6.9 8.7 7.2 6.7 8.7 1.1 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus PRR20 PF15708.5 EPS27337.1 - 0.26 11.2 0.1 0.26 11.2 0.1 2.0 2 0 0 2 2 2 0 Proline-rich protein family 20 Es2 PF09751.9 EPS27339.1 - 6.8e-140 467.6 11.4 8.1e-140 467.4 11.4 1.0 1 0 0 1 1 1 1 Nuclear protein Es2 DUF4515 PF14988.6 EPS27339.1 - 0.21 11.4 3.2 0.19 11.6 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4515) Oxidored-like PF09791.9 EPS27340.1 - 6.3e-05 22.6 7.0 6.3e-05 22.6 7.0 2.3 4 0 0 4 4 4 1 Oxidoreductase-like protein, N-terminal Mid1 PF12929.7 EPS27341.1 - 1.2e-161 538.7 5.0 1.5e-161 538.4 5.0 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 EPS27341.1 - 0.0033 18.0 5.6 0.039 14.6 2.1 2.7 2 0 0 2 2 2 2 Fz domain CorA PF01544.18 EPS27342.1 - 1.8e-44 152.2 0.0 2.5e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF3346 PF11826.8 EPS27343.1 - 0.011 15.6 0.0 0.013 15.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3346) GHMP_kinases_N PF00288.26 EPS27344.1 - 8.2e-11 42.0 0.1 1.7e-10 41.0 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EPS27344.1 - 7.7e-06 26.2 0.0 1.6e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal zf-rbx1 PF12678.7 EPS27346.1 - 3.5e-25 88.0 12.9 5.2e-25 87.5 12.9 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EPS27346.1 - 2.1e-17 62.9 10.4 2.9e-17 62.5 10.4 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 EPS27346.1 - 2.6e-06 27.7 14.7 9.1e-05 22.7 14.7 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EPS27346.1 - 9.5e-05 22.2 3.7 9.5e-05 22.2 3.7 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPS27346.1 - 0.0021 17.9 12.4 0.036 13.9 12.4 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 EPS27346.1 - 0.097 12.9 8.7 0.41 10.9 8.9 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 EPS27346.1 - 0.21 11.5 10.7 0.52 10.2 4.3 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EPS27346.1 - 0.53 9.9 14.9 0.12 12.0 4.8 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 EPS27346.1 - 0.67 9.8 16.6 0.5 10.2 9.4 2.5 1 1 1 2 2 2 0 RING-like zinc finger zf-RING_UBOX PF13445.6 EPS27346.1 - 0.72 9.9 8.6 2.7 8.1 8.6 2.0 1 1 0 1 1 1 0 RING-type zinc-finger PNRC PF15365.6 EPS27347.1 - 1e-08 34.7 7.7 1e-08 34.7 7.7 4.7 4 0 0 4 4 4 1 Proline-rich nuclear receptor coactivator motif SMI1_KNR4 PF09346.10 EPS27348.1 - 8.4e-34 116.8 0.0 1.7e-33 115.8 0.0 1.6 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) SUKH_6 PF14568.6 EPS27348.1 - 0.0086 16.5 0.0 0.048 14.1 0.0 2.1 1 1 0 1 1 1 1 SMI1-KNR4 cell-wall SUKH_5 PF14567.6 EPS27348.1 - 0.076 12.8 0.1 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall Thioredoxin PF00085.20 EPS27349.1 - 7.5e-05 22.7 0.0 0.00011 22.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin SesA PF17107.5 EPS27350.1 - 2.3e-19 69.8 0.0 3.5e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases Ank_5 PF13857.6 EPS27351.1 - 7.8e-10 38.8 3.5 6e-05 23.2 0.1 4.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EPS27351.1 - 3.9e-09 37.0 0.4 0.024 15.2 0.1 4.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPS27351.1 - 5.8e-07 29.9 4.1 0.046 14.3 0.0 5.5 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPS27351.1 - 0.0012 19.1 2.7 16 6.5 0.0 5.4 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.30 EPS27351.1 - 0.046 14.2 9.2 9 6.9 0.2 5.4 5 1 0 5 5 5 0 Ankyrin repeat EamA PF00892.20 EPS27352.1 - 6.8e-06 26.3 8.3 6.8e-06 26.3 8.3 2.2 2 0 0 2 2 2 1 EamA-like transporter family DUF1077 PF06417.12 EPS27352.1 - 0.5 10.4 6.3 7.4 6.6 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1077) Multi_Drug_Res PF00893.19 EPS27352.1 - 0.7 10.6 13.7 1.3 9.7 4.0 2.9 2 1 0 2 2 2 0 Small Multidrug Resistance protein Herpes_LMP1 PF05297.11 EPS27352.1 - 4.5 6.4 7.8 3.4 6.8 3.2 2.1 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) DUF2431 PF10354.9 EPS27353.1 - 9.7e-64 214.7 0.0 2.7e-63 213.2 0.0 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF2431) Presenilin PF01080.17 EPS27353.1 - 0.17 10.6 3.2 0.21 10.3 2.7 1.5 2 0 0 2 2 2 0 Presenilin FAM176 PF14851.6 EPS27353.1 - 0.17 11.5 6.3 4.4 6.9 0.1 2.5 2 0 0 2 2 2 0 FAM176 family TEX19 PF15553.6 EPS27353.1 - 0.32 10.9 5.3 1.3 8.9 0.4 2.7 2 0 0 2 2 2 0 Testis-expressed protein 19 DUF4611 PF15387.6 EPS27353.1 - 1.8 8.8 11.4 2.2 8.6 1.7 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) CLTH PF10607.9 EPS27354.1 - 5e-37 127.1 0.1 8.5e-37 126.3 0.1 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EPS27354.1 - 0.0086 16.0 0.0 0.021 14.8 0.0 1.7 1 0 0 1 1 1 1 LisH PAT1 PF09770.9 EPS27354.1 - 0.017 13.4 2.6 0.021 13.1 2.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3673 PF12425.8 EPS27354.1 - 0.14 12.1 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3673) DKCLD PF08068.12 EPS27355.1 - 2.4e-32 110.8 0.2 7.4e-31 106.0 0.1 2.5 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 EPS27355.1 - 5.3e-24 84.1 0.5 9.4e-24 83.3 0.5 1.4 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 EPS27355.1 - 2.4e-23 83.2 0.1 2.1e-20 73.6 0.1 3.4 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 EPS27355.1 - 4.3e-22 77.9 1.4 8.4e-22 76.9 1.4 1.5 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 EPS27355.1 - 0.00081 19.6 0.0 0.0021 18.3 0.0 1.7 1 0 0 1 1 1 1 UPF0113 PUA domain Med19 PF10278.9 EPS27355.1 - 0.015 15.3 12.4 0.024 14.6 12.4 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 TFIIF_alpha PF05793.12 EPS27355.1 - 0.17 10.4 20.5 0.22 10.1 20.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MCM_bind PF09739.9 EPS27355.1 - 1.5 7.2 7.7 1.9 6.8 7.7 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor NAM-associated PF14303.6 EPS27355.1 - 1.7 9.3 19.0 2.7 8.7 19.0 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Peptidase_S49_N PF08496.10 EPS27355.1 - 2.7 8.1 7.5 5 7.2 7.5 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RNA_polI_A34 PF08208.11 EPS27355.1 - 5.4 7.0 24.4 10 6.1 24.4 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 PGA2 PF07543.12 EPS27355.1 - 6.7 6.7 15.7 11 6.0 15.7 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 CDC45 PF02724.14 EPS27355.1 - 8.4 4.5 15.3 11 4.2 15.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DER1 PF04511.15 EPS27356.1 - 3.3e-26 92.4 3.1 3.8e-26 92.2 3.1 1.0 1 0 0 1 1 1 1 Der1-like family Papilloma_E5A PF05776.12 EPS27356.1 - 0.11 12.8 5.1 0.45 10.9 4.0 2.1 2 0 0 2 2 2 0 Papillomavirus E5A protein PetL PF05115.14 EPS27356.1 - 0.84 9.7 5.6 2.1 8.4 5.6 1.7 1 0 0 1 1 1 0 Cytochrome B6-F complex subunit VI (PetL) MaoC_dehydratas PF01575.19 EPS27357.1 - 0.0021 17.6 0.0 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain PDT PF00800.18 EPS27358.1 - 1.5e-64 217.2 0.0 1.9e-64 216.9 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.25 EPS27358.1 - 0.0011 18.7 0.0 0.0023 17.6 0.0 1.6 1 0 0 1 1 1 1 ACT domain eRF1_2 PF03464.15 EPS27359.1 - 7.1e-48 162.3 0.1 1.2e-47 161.6 0.1 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EPS27359.1 - 1.2e-39 135.2 0.3 2.9e-39 134.0 0.3 1.7 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 EPS27359.1 - 3.2e-22 78.9 0.0 5.3e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 EPS27359.1 - 3.9e-09 36.9 0.0 7.1e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 EPS27359.1 - 1.7e-07 31.6 0.0 2.7e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor DUF3440 PF11922.8 EPS27359.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) Aa_trans PF01490.18 EPS27360.1 - 7.7e-65 219.2 20.7 9e-65 219.0 20.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MerC PF03203.14 EPS27360.1 - 0.011 16.2 0.2 0.011 16.2 0.2 3.4 3 1 1 4 4 4 0 MerC mercury resistance protein Trp_Tyr_perm PF03222.13 EPS27360.1 - 0.039 13.0 14.4 0.022 13.8 7.5 2.3 2 0 0 2 2 2 0 Tryptophan/tyrosine permease family Bmt2 PF11968.8 EPS27361.1 - 2.2e-90 302.3 0.0 2.9e-90 302.0 0.0 1.1 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Ribosomal_L23eN PF03939.13 EPS27362.1 - 1.2e-24 86.3 7.2 2.3e-24 85.3 7.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 EPS27362.1 - 3.7e-16 59.3 0.7 3.7e-16 59.3 0.7 1.6 2 0 0 2 2 2 1 Ribosomal protein L23 Linker_histone PF00538.19 EPS27362.1 - 0.09 13.2 2.2 0.1 13.0 0.4 1.9 2 0 0 2 2 2 0 linker histone H1 and H5 family zf-Tim10_DDP PF02953.15 EPS27363.1 - 6.6e-22 76.9 3.6 8.1e-22 76.7 3.6 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Keratin PF02422.16 EPS27363.1 - 0.25 11.1 1.8 2.5 7.9 0.2 2.1 1 1 1 2 2 2 0 Keratin G10 PF01125.17 EPS27364.1 - 7.6e-68 226.9 5.0 8.4e-68 226.7 5.0 1.0 1 0 0 1 1 1 1 G10 protein Forkhead PF00250.18 EPS27365.1 - 3e-35 120.3 0.0 5.1e-35 119.6 0.0 1.4 1 0 0 1 1 1 1 Forkhead domain AA_kinase PF00696.28 EPS27368.1 - 7.9e-43 146.8 0.1 1.2e-42 146.2 0.1 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.6 EPS27368.1 - 2.2e-11 43.4 1.2 1.8e-09 37.3 0.1 2.4 2 0 0 2 2 2 2 ACT domain ACT PF01842.25 EPS27368.1 - 3.9e-10 39.3 2.7 1.2e-07 31.3 0.1 3.4 3 0 0 3 3 3 2 ACT domain Gag_p24 PF00607.20 EPS27368.1 - 0.059 13.2 0.1 0.18 11.6 0.0 1.7 2 0 0 2 2 2 0 gag gene protein p24 (core nucleocapsid protein) Goodbye PF17109.5 EPS27369.1 - 0.04 14.4 0.2 0.16 12.4 0.0 2.1 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain FliS PF02561.14 EPS27369.1 - 0.048 13.9 2.9 2.6 8.3 0.0 3.0 2 1 1 3 3 3 0 Flagellar protein FliS Fer4_23 PF18009.1 EPS27369.1 - 0.17 12.4 0.1 0.42 11.1 0.1 1.6 1 0 0 1 1 1 0 4Fe-4S iron-sulfur cluster binding domain AAA PF00004.29 EPS27370.1 - 2.2e-16 60.5 0.0 5.1e-16 59.3 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EPS27370.1 - 0.016 15.6 0.1 0.058 13.8 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EPS27370.1 - 0.016 15.5 2.2 0.24 11.7 0.2 2.9 1 1 1 2 2 2 0 AAA domain AAA_30 PF13604.6 EPS27370.1 - 0.16 11.6 0.2 0.31 10.7 0.2 1.4 1 0 0 1 1 1 0 AAA domain Torsin PF06309.11 EPS27370.1 - 0.2 11.8 0.0 0.42 10.7 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_28 PF13521.6 EPS27370.1 - 0.34 11.1 1.9 9.5 6.4 0.7 3.1 2 1 1 3 3 3 0 AAA domain Peptidase_C78 PF07910.13 EPS27371.1 - 3.9e-71 238.9 0.0 5.3e-71 238.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 zf-Di19 PF05605.12 EPS27371.1 - 0.015 15.6 6.0 1.2 9.5 1.8 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf_UBZ PF18439.1 EPS27371.1 - 0.072 12.7 0.0 0.072 12.7 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_12 PF18658.1 EPS27371.1 - 0.16 11.5 0.6 0.3 10.7 0.2 1.7 2 0 0 2 2 2 0 Zinc-finger C2H2-type zf-C2H2_4 PF13894.6 EPS27371.1 - 1.4 10.0 7.0 27 6.0 0.1 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger AAA_18 PF13238.6 EPS27372.1 - 1.8e-25 90.0 0.0 3.1e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EPS27372.1 - 2.6e-07 31.1 0.0 6.6e-07 29.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EPS27372.1 - 0.00077 19.7 0.2 0.001 19.4 0.2 1.6 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EPS27372.1 - 0.0011 19.4 0.0 0.0017 18.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EPS27372.1 - 0.0019 18.4 0.0 0.01 16.0 0.0 1.9 1 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EPS27372.1 - 0.002 18.5 0.0 0.0032 17.9 0.0 1.3 1 0 0 1 1 1 1 RNA helicase ADK PF00406.22 EPS27372.1 - 0.0027 17.8 0.1 0.011 15.9 0.1 2.1 1 1 0 1 1 1 1 Adenylate kinase AAA_22 PF13401.6 EPS27372.1 - 0.0085 16.4 0.0 0.019 15.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EPS27372.1 - 0.012 15.7 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EPS27372.1 - 0.014 15.8 0.1 0.031 14.6 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 EPS27372.1 - 0.015 15.2 0.2 0.044 13.7 0.1 1.8 2 0 0 2 2 2 0 NTPase KTI12 PF08433.10 EPS27372.1 - 0.033 13.6 0.0 0.055 12.9 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Hydin_ADK PF17213.3 EPS27372.1 - 0.051 13.8 0.0 0.084 13.1 0.0 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain AAA_24 PF13479.6 EPS27372.1 - 0.12 12.1 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 EPS27372.1 - 0.14 11.8 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 EPS27372.1 - 0.15 11.8 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Ham1p_like PF01725.16 EPS27373.1 - 1.4e-61 207.7 0.0 1.5e-61 207.6 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Myosin_head PF00063.21 EPS27374.1 - 1.7e-264 879.2 3.0 2.6e-264 878.6 3.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 EPS27374.1 - 8.3e-27 93.5 10.7 2.8e-26 91.8 3.0 3.1 2 0 0 2 2 2 1 DIL domain IQ PF00612.27 EPS27374.1 - 4.4e-15 54.0 28.6 0.00011 21.7 0.1 7.1 6 0 0 6 6 6 5 IQ calmodulin-binding motif Myosin_N PF02736.19 EPS27374.1 - 1.1e-05 25.2 1.4 2.9e-05 23.8 1.4 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 EPS27374.1 - 0.00017 21.9 0.0 0.0011 19.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain Spc7 PF08317.11 EPS27374.1 - 0.0046 15.9 20.6 0.011 14.6 20.6 1.7 1 0 0 1 1 1 1 Spc7 kinetochore protein AAA_16 PF13191.6 EPS27374.1 - 0.016 15.6 0.0 0.016 15.6 0.0 2.6 2 1 0 2 2 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 EPS27374.1 - 0.057 13.3 0.0 0.18 11.7 0.0 1.9 1 0 0 1 1 1 0 RsgA GTPase RNA_helicase PF00910.22 EPS27374.1 - 0.1 13.0 0.0 0.66 10.4 0.0 2.5 2 0 0 2 2 1 0 RNA helicase Baculo_PEP_C PF04513.12 EPS27374.1 - 0.14 12.2 3.8 0.13 12.4 1.2 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3450 PF11932.8 EPS27374.1 - 0.58 9.4 26.4 0.64 9.3 9.9 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) ABC_tran PF00005.27 EPS27374.1 - 1.2 9.6 3.4 1.2 9.6 0.0 2.7 2 1 0 2 2 2 0 ABC transporter GAS PF13851.6 EPS27374.1 - 1.5 8.2 27.1 1.7 8.0 13.1 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding KASH_CCD PF14662.6 EPS27374.1 - 1.8 8.4 29.5 0.046 13.5 9.9 2.8 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH FUSC PF04632.12 EPS27374.1 - 2.7 6.4 7.1 5 5.5 7.1 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein family Pterin_bind PF00809.22 EPS27375.1 - 0.014 15.1 0.0 0.016 14.9 0.0 1.1 1 0 0 1 1 1 0 Pterin binding enzyme NAP PF00956.18 EPS27376.1 - 1.9e-98 328.9 11.4 1.9e-98 328.9 11.4 1.5 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Afaf PF15339.6 EPS27376.1 - 2.8 7.6 6.5 0.41 10.3 1.4 2.0 2 0 0 2 2 2 0 Acrosome formation-associated factor P5-ATPase PF12409.8 EPS27378.1 - 4e-39 133.6 0.2 5.8e-38 129.8 0.0 2.6 3 0 0 3 3 3 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 EPS27378.1 - 2.6e-33 115.0 0.1 9e-33 113.3 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EPS27378.1 - 2.7e-13 50.7 0.2 0.00025 21.4 0.0 3.4 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EPS27378.1 - 4.8e-05 23.4 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_C PF00689.21 EPS27378.1 - 0.0001 22.1 7.5 0.0001 22.1 7.5 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase_3 PF08282.12 EPS27378.1 - 0.096 12.4 0.1 10 5.7 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase CBP_BcsF PF11120.8 EPS27378.1 - 1.8 8.7 5.0 0.69 10.1 0.5 2.5 2 1 0 2 2 2 0 Cellulose biosynthesis protein BcsF NADH_B2 PF14813.6 EPS27379.1 - 0.024 14.4 0.2 0.027 14.3 0.2 1.1 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 Pkinase PF00069.25 EPS27380.1 - 2.6e-67 227.0 0.0 3.1e-67 226.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS27380.1 - 2e-32 112.5 0.0 2.7e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EPS27380.1 - 0.0014 17.7 0.0 0.002 17.1 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 EPS27380.1 - 0.031 13.9 0.0 3.2 7.3 0.0 2.2 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EPS27380.1 - 0.045 12.5 0.0 0.067 12.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EPS27380.1 - 0.072 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EPS27380.1 - 0.14 11.5 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EPS27380.1 - 0.23 10.7 0.0 0.62 9.3 0.0 1.7 1 1 0 1 1 1 0 Kinase-like 2-Hacid_dh_C PF02826.19 EPS27381.1 - 2.6e-51 173.5 0.0 4.2e-51 172.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EPS27381.1 - 1.2e-37 128.5 0.0 1.6e-37 128.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EPS27381.1 - 0.00022 21.4 0.2 0.00056 20.1 0.2 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.25 EPS27381.1 - 0.0011 18.7 0.0 0.0025 17.6 0.0 1.7 1 0 0 1 1 1 1 ACT domain IlvN PF07991.12 EPS27381.1 - 0.0028 17.2 0.2 0.15 11.6 0.0 2.3 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 EPS27381.1 - 0.022 14.8 0.0 0.053 13.6 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.6 EPS27381.1 - 0.023 15.2 0.0 0.074 13.6 0.0 1.9 2 0 0 2 2 2 0 XdhC Rossmann domain DUF1780 PF08682.10 EPS27381.1 - 0.095 12.4 0.0 0.23 11.1 0.0 1.6 2 0 0 2 2 2 0 Putative endonuclease, protein of unknown function (DUF1780) 3HCDH_N PF02737.18 EPS27381.1 - 0.14 12.0 0.2 0.58 10.0 0.2 2.1 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain tRNA-synt_2b PF00587.25 EPS27382.1 - 1e-37 129.8 0.2 2.1e-37 128.8 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EPS27382.1 - 3.8e-19 68.9 6.9 3.8e-19 68.9 6.9 2.4 3 0 0 3 3 3 1 Seryl-tRNA synthetase N-terminal domain DUF1492 PF07374.11 EPS27382.1 - 0.12 12.5 1.3 0.38 11.0 1.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1492) Cytochrom_C552 PF02335.15 EPS27382.1 - 0.35 9.7 8.1 0.23 10.3 0.2 2.3 2 0 0 2 2 2 0 Cytochrome c552 Ras PF00071.22 EPS27383.1 - 4.5e-46 156.4 0.3 5.1e-46 156.2 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EPS27383.1 - 6.8e-17 61.8 0.0 8.9e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPS27383.1 - 5.2e-09 35.8 0.0 5.7e-09 35.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EPS27383.1 - 6.4e-06 25.8 0.3 0.0002 21.0 0.1 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EPS27383.1 - 1.3e-05 25.2 0.1 1.8e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EPS27383.1 - 0.00035 20.0 0.0 0.00053 19.5 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EPS27383.1 - 0.0018 18.2 0.1 0.35 10.8 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase AAA_28 PF13521.6 EPS27383.1 - 0.01 16.1 0.0 0.017 15.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EPS27383.1 - 0.027 14.5 0.0 0.047 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 EPS27383.1 - 0.1 12.0 0.1 0.31 10.4 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein FeoB_N PF02421.18 EPS27383.1 - 0.14 11.7 0.0 0.25 10.9 0.0 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B WAPL PF07814.13 EPS27384.1 - 9.3e-75 251.7 7.9 1.7e-74 250.8 7.9 1.5 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin Creb_binding PF09030.10 EPS27384.1 - 0.0019 18.9 4.7 0.0019 18.8 0.0 3.3 4 0 0 4 4 4 1 Creb binding Wap1 PF16997.5 EPS27384.1 - 0.0035 16.5 0.6 0.11 11.6 1.6 2.3 2 0 0 2 2 2 1 Wap1 domain UPRTase PF14681.6 EPS27385.1 - 4.5e-77 258.2 0.0 5.6e-77 257.9 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EPS27385.1 - 0.0089 15.6 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.13 EPS27385.1 - 0.2 11.6 0.1 0.31 11.0 0.1 1.2 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Elf1 PF05129.13 EPS27386.1 - 1.1e-28 99.1 0.1 1.4e-28 98.8 0.1 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-Sec23_Sec24 PF04810.15 EPS27386.1 - 0.01 15.9 0.6 0.93 9.6 0.2 2.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger EST1_DNA_bind PF10373.9 EPS27386.1 - 0.054 13.0 0.0 0.071 12.6 0.0 1.1 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain Vps36-NZF-N PF16988.5 EPS27386.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain CSN7a_helixI PF18392.1 EPS27386.1 - 0.11 12.5 0.4 8.8 6.3 0.0 2.2 2 0 0 2 2 2 0 COP9 signalosome complex subunit 7a helix I domain Zn-ribbon_8 PF09723.10 EPS27386.1 - 0.11 12.7 0.2 0.25 11.5 0.2 1.7 1 1 0 1 1 1 0 Zinc ribbon domain Peptidase_U32 PF01136.19 EPS27386.1 - 0.16 11.1 0.0 0.19 10.9 0.0 1.0 1 0 0 1 1 1 0 Peptidase family U32 Ribosomal_S3Ae PF01015.18 EPS27387.1 - 7.4e-88 293.4 2.7 9.2e-88 293.1 2.7 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 EPS27387.1 - 0.016 15.7 0.1 0.16 12.5 0.0 2.3 2 0 0 2 2 2 0 Translation initiation factor SUI1 NEMO PF11577.8 EPS27387.1 - 0.087 12.8 0.5 0.7 10.0 0.0 2.3 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO Prok-RING_2 PF14445.6 EPS27388.1 - 0.09 13.0 0.6 6.1 7.1 0.3 2.7 2 1 0 2 2 2 0 Prokaryotic RING finger family 2 adh_short PF00106.25 EPS27392.1 - 1.4e-20 73.6 0.0 1.4e-18 67.1 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EPS27392.1 - 3.5e-10 39.8 0.0 7.1e-10 38.8 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPS27392.1 - 0.00022 21.2 0.0 0.00036 20.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPS27392.1 - 0.025 14.0 0.0 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EPS27392.1 - 0.027 14.7 0.0 0.072 13.3 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 EPS27392.1 - 0.12 11.8 0.0 0.22 10.9 0.0 1.4 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase YpjP PF14005.6 EPS27393.1 - 0.0065 16.5 1.6 0.0077 16.3 1.6 1.1 1 0 0 1 1 1 1 YpjP-like protein Mor PF08765.11 EPS27393.1 - 0.25 11.3 2.0 0.89 9.6 1.9 1.9 1 1 0 1 1 1 0 Mor transcription activator family Arm-DNA-bind_2 PF12167.8 EPS27393.1 - 5 7.1 9.2 87 3.1 8.7 2.2 1 1 0 1 1 1 0 Arm DNA-binding domain Fungal_trans PF04082.18 EPS27395.1 - 1.3e-08 34.2 0.1 2.4e-08 33.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS27395.1 - 1.1e-07 31.8 10.9 2.9e-07 30.5 10.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SWIRM PF04433.17 EPS27397.1 - 5.8e-11 42.6 0.0 1.2e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain CDC50 PF03381.15 EPS27398.1 - 7.2e-96 321.0 0.0 8.7e-96 320.7 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Peptidase_M43 PF05572.13 EPS27399.1 - 2.3e-10 40.6 0.0 6.6e-10 39.1 0.0 1.8 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 EPS27399.1 - 0.0038 17.4 5.5 0.014 15.5 5.5 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12 SopD PF11047.8 EPS27399.1 - 0.017 14.3 0.0 0.023 13.9 0.0 1.1 1 0 0 1 1 1 0 Salmonella outer protein D Reprolysin_2 PF13574.6 EPS27399.1 - 0.035 14.0 0.1 0.044 13.7 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 EPS27399.1 - 0.06 13.0 0.0 0.094 12.3 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 EPS27399.1 - 0.12 12.9 0.8 0.21 12.1 0.3 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like SPT16 PF08644.11 EPS27400.1 - 2.2e-58 196.7 0.0 6.7e-58 195.1 0.0 1.9 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 EPS27400.1 - 3.7e-54 182.9 0.4 1.5e-53 180.9 0.4 2.2 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 EPS27400.1 - 2.8e-26 92.5 0.0 4.8e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 EPS27400.1 - 1.1e-14 54.6 0.1 3.3e-14 53.1 0.0 1.9 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Mito_carr PF00153.27 EPS27401.1 - 3e-19 68.7 2.9 6.4e-14 51.6 0.1 3.4 3 1 0 3 3 3 2 Mitochondrial carrier protein Sugar_tr PF00083.24 EPS27402.1 - 7.7e-101 338.2 16.3 9.3e-101 337.9 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS27402.1 - 3.4e-31 108.5 51.4 6.3e-28 97.7 22.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EPS27402.1 - 6.8e-09 34.8 16.9 8.9e-05 21.2 6.3 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 EPS27402.1 - 0.058 12.2 8.0 0.89 8.3 0.1 2.3 1 1 1 2 2 2 0 MFS_1 like family PMT PF02366.18 EPS27403.1 - 2.8e-89 298.9 14.7 2.8e-89 298.9 14.7 2.3 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 EPS27403.1 - 2.7e-63 213.2 14.8 2.7e-63 213.2 14.8 2.3 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 EPS27403.1 - 6.3e-35 120.7 0.3 1.1e-34 119.9 0.3 1.3 1 0 0 1 1 1 1 MIR domain DUF5455 PF17537.2 EPS27403.1 - 0.012 16.0 0.3 0.091 13.2 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5455) Ras PF00071.22 EPS27404.1 - 6.4e-48 162.4 0.0 2.5e-37 128.0 0.1 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EPS27404.1 - 8.5e-28 97.0 0.0 3.1e-17 62.9 0.0 2.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPS27404.1 - 5.3e-12 45.5 0.0 2.4e-11 43.4 0.1 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EPS27404.1 - 9e-09 35.1 0.0 1.4e-07 31.2 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EPS27404.1 - 7.7e-05 22.2 0.1 0.00026 20.4 0.1 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EPS27404.1 - 0.00027 21.0 0.0 0.0032 17.5 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EPS27404.1 - 0.0014 18.6 0.0 0.64 9.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Flu_M1_C PF08289.11 EPS27404.1 - 0.025 14.8 0.1 0.043 14.0 0.1 1.3 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain AAA_30 PF13604.6 EPS27404.1 - 0.067 12.9 0.1 0.44 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EPS27404.1 - 0.067 13.6 0.4 1.8 8.9 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 EPS27404.1 - 0.092 13.0 0.4 1.3 9.3 0.1 2.3 3 0 0 3 3 3 0 AAA domain Choline_transpo PF04515.12 EPS27405.1 - 1.3e-24 87.0 22.6 1.3e-24 87.0 22.6 2.2 2 0 0 2 2 2 2 Plasma-membrane choline transporter PspB PF06667.12 EPS27405.1 - 4.6 7.4 5.3 27 4.9 0.3 2.7 2 0 0 2 2 2 0 Phage shock protein B Aldo_ket_red PF00248.21 EPS27407.1 - 8e-41 140.1 0.0 6e-32 111.0 0.0 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family UPF0061 PF02696.14 EPS27408.1 - 6.8e-126 420.8 0.0 8.5e-126 420.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family DUF4391 PF14335.6 EPS27408.1 - 0.0069 16.1 0.2 0.011 15.4 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4391) zf-CCHC PF00098.23 EPS27409.1 - 7.5e-52 171.2 63.3 9.7e-09 34.9 1.9 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 EPS27409.1 - 4.4e-16 58.4 40.0 0.011 15.5 1.2 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.6 EPS27409.1 - 1.4e-07 31.4 50.8 0.0027 17.7 2.0 7.0 2 2 5 7 7 7 6 Zinc knuckle zf-CCHC_5 PF14787.6 EPS27409.1 - 0.00032 20.3 45.7 0.57 9.9 0.5 7.1 5 2 2 7 7 7 6 GAG-polyprotein viral zinc-finger zf-CCHC_6 PF15288.6 EPS27409.1 - 0.00093 19.0 50.0 0.13 12.1 3.3 6.9 6 1 1 7 7 7 6 Zinc knuckle zf-CCHC_2 PF13696.6 EPS27409.1 - 0.0076 16.0 1.5 0.0076 16.0 1.5 7.3 7 1 0 7 7 7 1 Zinc knuckle F-box-like PF12937.7 EPS27410.1 - 2e-08 34.0 0.7 5.6e-08 32.5 0.7 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EPS27410.1 - 4.9e-08 32.7 1.9 1.2e-07 31.4 1.9 1.7 1 0 0 1 1 1 1 F-box domain WD40 PF00400.32 EPS27410.1 - 0.16 12.9 2.0 71 4.5 0.1 4.1 4 0 0 4 4 4 0 WD domain, G-beta repeat SAE2 PF08573.10 EPS27411.1 - 9e-35 120.2 1.7 9e-35 120.2 1.7 3.3 3 0 0 3 3 3 1 DNA repair protein endonuclease SAE2/CtIP C-terminus PMEI PF04043.15 EPS27411.1 - 0.039 14.3 1.4 0.12 12.7 1.4 1.8 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor FAIM1 PF06905.13 EPS27411.1 - 0.088 12.5 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Fas apoptotic inhibitory molecule (FAIM1) Baculo_PEP_C PF04513.12 EPS27411.1 - 2.2 8.3 4.7 0.63 10.1 1.6 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATF7IP_BD PF16788.5 EPS27411.1 - 2.5 8.1 7.3 0.18 11.9 0.9 2.3 2 0 0 2 2 2 0 ATF-interacting protein binding domain Pex16 PF08610.10 EPS27412.1 - 6.9e-140 465.8 0.3 7.9e-140 465.6 0.3 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) RNase_HII PF01351.18 EPS27413.1 - 3.9e-46 157.4 0.0 8.2e-46 156.3 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease HII CENP-C_C PF11699.8 EPS27414.1 - 2.4e-35 120.6 0.9 4.1e-35 119.8 0.9 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.6 EPS27414.1 - 9e-24 84.7 3.7 9e-24 84.7 3.7 3.5 2 1 1 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.11 EPS27414.1 - 2.7e-05 23.8 0.0 8.8e-05 22.1 0.0 1.9 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 EPS27414.1 - 0.0069 16.0 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 Cupin CAP_GLY PF01302.25 EPS27415.1 - 6.1e-25 87.0 0.0 9e-25 86.5 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 EPS27415.1 - 2.1e-15 56.9 0.0 3.3e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.23 EPS27415.1 - 2.5e-05 23.9 0.0 0.0002 21.0 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin family Methyltransf_11 PF08241.12 EPS27416.1 - 1.3e-14 54.6 0.1 2.2e-14 53.8 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPS27416.1 - 1.1e-11 45.3 0.1 1.8e-11 44.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPS27416.1 - 5.2e-09 36.1 0.0 8e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPS27416.1 - 4.1e-07 29.9 0.0 6.3e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPS27416.1 - 1.2e-06 29.1 0.1 2.1e-06 28.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EPS27416.1 - 0.0036 17.2 0.0 0.0051 16.7 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase MetW PF07021.12 EPS27416.1 - 0.021 14.4 0.1 0.044 13.4 0.1 1.5 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.11 EPS27416.1 - 0.1 11.5 0.1 0.44 9.4 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) TehB PF03848.14 EPS27416.1 - 0.23 10.9 0.0 0.38 10.1 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Myb_DNA-binding PF00249.31 EPS27417.1 - 1.8e-14 53.6 2.5 2.6e-11 43.5 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EPS27417.1 - 3e-06 27.4 3.7 0.0026 18.0 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain AGOG PF09171.10 EPS27417.1 - 0.14 11.5 0.1 0.2 11.0 0.1 1.1 1 0 0 1 1 1 0 N-glycosylase/DNA lyase DUF5427 PF10310.9 EPS27418.1 - 1 8.2 15.7 1.2 8.0 15.7 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Presenilin PF01080.17 EPS27418.1 - 4.2 6.0 16.3 4.2 6.0 16.3 1.0 1 0 0 1 1 1 0 Presenilin Rubella_Capsid PF05750.11 EPS27418.1 - 4.4 6.8 12.6 4.7 6.7 12.6 1.1 1 0 0 1 1 1 0 Rubella capsid protein DDHD PF02862.17 EPS27418.1 - 4.7 7.3 6.7 5.9 7.0 6.7 1.2 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.12 EPS27418.1 - 5.8 6.6 17.7 6.8 6.4 17.7 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNA_pol_Rpc4 PF05132.14 EPS27418.1 - 9.2 6.7 12.0 11 6.4 12.0 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Ribosomal_60s PF00428.19 EPS27420.1 - 4.8 7.8 13.7 7.6 7.2 13.7 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein UCH PF00443.29 EPS27421.1 - 1.1e-24 87.4 0.5 1.6e-24 86.8 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EPS27421.1 - 8.6e-17 61.7 0.6 1.6e-16 60.9 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EPS27421.1 - 0.062 12.8 2.0 0.17 11.4 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase MitMem_reg PF13012.6 EPS27423.1 - 3.2e-37 127.4 0.5 5.5e-37 126.6 0.5 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EPS27423.1 - 5.9e-32 110.1 0.0 1.4e-31 108.9 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease tRNA_bind_2 PF13725.6 EPS27423.1 - 0.17 11.5 6.7 0.26 10.9 6.7 1.2 1 0 0 1 1 1 0 Possible tRNA binding domain Connexin PF00029.19 EPS27423.1 - 0.57 9.9 2.8 0.87 9.3 2.8 1.4 1 0 0 1 1 1 0 Connexin CobT PF06213.12 EPS27423.1 - 3.4 7.0 12.6 4.9 6.5 12.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT ADK PF00406.22 EPS27424.1 - 1e-58 197.7 0.0 1.3e-58 197.4 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EPS27424.1 - 2.7e-22 79.7 0.0 4.5e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 EPS27424.1 - 5.7e-18 64.6 0.1 1.3e-17 63.5 0.0 1.6 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_18 PF13238.6 EPS27424.1 - 1.1e-05 26.0 0.0 1.7e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EPS27424.1 - 0.00011 22.4 0.0 0.00017 21.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain GFO_IDH_MocA PF01408.22 EPS27425.1 - 1.6e-16 61.2 0.1 2.4e-16 60.6 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 EPS27425.1 - 0.00027 21.6 0.1 0.00041 21.0 0.1 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Attachment_P66 PF11263.8 EPS27425.1 - 0.12 11.6 0.0 0.28 10.4 0.0 1.5 1 0 0 1 1 1 0 Borrelia burgdorferi attachment protein P66 GFO_IDH_MocA_C PF02894.17 EPS27425.1 - 0.14 12.2 0.0 0.33 11.0 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain CFIA_Pcf11 PF11526.8 EPS27426.1 - 6e-08 33.1 0.1 1.6e-07 31.7 0.1 1.8 1 0 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 CTD_bind PF04818.13 EPS27426.1 - 9.2e-06 26.4 0.0 3.4e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase II-binding domain. VHS PF00790.19 EPS27426.1 - 0.034 14.0 0.0 0.068 13.0 0.0 1.4 1 0 0 1 1 1 0 VHS domain zf_UBZ PF18439.1 EPS27426.1 - 0.14 11.8 5.1 0.38 10.4 0.8 2.8 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-ISL3 PF14690.6 EPS27426.1 - 1.1 10.0 3.6 0.32 11.7 0.4 1.7 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C2HC_2 PF13913.6 EPS27426.1 - 7.5 6.6 6.3 19 5.3 0.2 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type HOOK PF05622.12 EPS27428.1 - 6.1e-28 97.4 65.2 1.5e-27 96.1 32.7 3.3 1 1 1 3 3 3 3 HOOK protein KASH_CCD PF14662.6 EPS27428.1 - 0.00059 19.7 76.2 0.19 11.5 19.0 4.7 2 2 2 4 4 4 4 Coiled-coil region of CCDC155 or KASH HMMR_N PF15905.5 EPS27428.1 - 0.003 17.1 71.3 0.021 14.3 37.1 3.3 2 1 1 3 3 3 2 Hyaluronan mediated motility receptor N-terminal RuBisCO_small PF00101.20 EPS27428.1 - 0.024 14.6 0.0 0.097 12.7 0.0 2.0 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase, small chain DUF3800 PF12686.7 EPS27428.1 - 0.084 13.5 0.3 4 8.1 0.3 3.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) GAS PF13851.6 EPS27428.1 - 0.098 12.0 74.3 0.0093 15.3 29.8 5.0 2 2 2 4 4 4 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 EPS27428.1 - 0.11 12.6 83.3 0.036 14.1 4.1 6.9 4 3 2 6 6 6 0 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 EPS27428.1 - 0.18 11.2 55.7 1.2 8.4 19.3 4.4 2 2 1 3 3 3 0 Domain of unknown function (DUF4407) HOCHOB PF17943.1 EPS27428.1 - 1.2 9.8 6.4 8.5 7.1 0.3 3.3 2 1 1 3 3 3 0 Homeobox-cysteine loop-homeobox Spc7 PF08317.11 EPS27428.1 - 1.4 7.7 79.9 1.5 7.6 4.4 5.0 2 2 3 5 5 5 0 Spc7 kinetochore protein Csm1_N PF18504.1 EPS27428.1 - 1.5 9.2 58.3 0.24 11.8 3.2 8.0 6 1 2 8 8 8 0 Csm1 N-terminal domain TraF_2 PF13729.6 EPS27428.1 - 1.7 7.9 12.3 0.13 11.6 2.7 3.2 3 0 0 3 3 3 0 F plasmid transfer operon, TraF, protein T2SSG PF08334.11 EPS27428.1 - 6.2 6.9 7.6 1.6 8.9 2.2 2.8 3 1 0 3 3 3 0 Type II secretion system (T2SS), protein G Coprogen_oxidas PF01218.18 EPS27429.1 - 4.5e-135 449.1 0.0 6e-135 448.7 0.0 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Fungal_trans PF04082.18 EPS27430.1 - 3e-17 62.5 0.2 4.9e-17 61.8 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS27430.1 - 5.8e-08 32.7 10.3 1.1e-07 31.9 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APG6_N PF17675.1 EPS27430.1 - 0.094 13.2 0.1 0.4 11.2 0.1 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region SelP_N PF04592.14 EPS27430.1 - 4.5 6.6 12.8 9.7 5.5 12.8 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Atg8 PF02991.16 EPS27432.1 - 2.7e-51 172.1 0.2 3.2e-51 171.8 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 EPS27432.1 - 3e-06 27.5 0.0 3.6e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Mito_carr PF00153.27 EPS27434.1 - 8.7e-30 102.5 0.7 4.3e-15 55.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein NCE101 PF11654.8 EPS27435.1 - 3.9e-07 29.7 0.4 5.2e-07 29.3 0.0 1.4 2 0 0 2 2 2 1 Non-classical export protein 1 HSP70 PF00012.20 EPS27436.1 - 1.7e-261 868.7 7.7 1.9e-261 868.5 7.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EPS27436.1 - 3.4e-19 68.8 0.1 3.8e-18 65.4 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EPS27436.1 - 0.0015 18.3 0.0 0.0036 17.1 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 EPS27436.1 - 0.0034 17.8 5.1 4.4 7.8 0.0 3.6 3 2 0 3 3 3 2 Cell division protein FtsA BcrAD_BadFG PF01869.20 EPS27436.1 - 0.024 14.2 0.1 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Hydantoinase_A PF01968.18 EPS27436.1 - 0.027 13.7 0.1 0.057 12.7 0.1 1.5 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase StbA PF06406.11 EPS27436.1 - 0.039 13.2 0.0 0.077 12.2 0.0 1.4 1 0 0 1 1 1 0 StbA protein OPT PF03169.15 EPS27437.1 - 4.9e-136 454.9 48.2 5.6e-136 454.7 48.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein ZYG-11_interact PF05884.12 EPS27437.1 - 0.27 10.6 2.2 0.91 8.9 0.2 2.3 2 0 0 2 2 2 0 Interactor of ZYG-11 CHZ PF09649.10 EPS27438.1 - 5.5e-14 51.3 3.1 5.5e-14 51.3 3.1 1.9 2 0 0 2 2 2 1 Histone chaperone domain CHZ Apc15p PF05841.11 EPS27440.1 - 3.6e-15 56.8 1.3 5.5e-15 56.3 0.2 1.8 2 0 0 2 2 2 1 Apc15p protein DUF963 PF06131.11 EPS27441.1 - 9.9e-23 79.3 107.4 1.3e-09 37.3 29.0 15.0 8 2 7 15 15 15 4 Schizosaccharomyces pombe repeat of unknown function (DUF963) GalBD_like PF17974.1 EPS27441.1 - 0.0049 17.0 0.2 0.0094 16.1 0.2 1.4 1 0 0 1 1 1 1 Galactose-binding domain-like Nop14 PF04147.12 EPS27442.1 - 0.0022 16.3 0.5 0.0025 16.1 0.5 1.0 1 0 0 1 1 1 1 Nop14-like family GATase_2 PF00310.21 EPS27443.1 - 5.4e-181 601.9 0.0 7.3e-181 601.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 EPS27443.1 - 6.3e-157 522.4 0.0 8.9e-157 521.9 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 EPS27443.1 - 5.6e-113 377.1 0.0 2.3e-110 368.5 0.0 2.2 2 0 0 2 2 2 2 Glutamate synthase central domain GXGXG PF01493.19 EPS27443.1 - 3.3e-85 284.5 2.5 5.3e-85 283.8 2.5 1.3 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 EPS27443.1 - 2.8e-27 95.7 0.1 2.4e-26 92.7 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 EPS27443.1 - 5.7e-21 74.4 0.0 1.1e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox PF00070.27 EPS27443.1 - 1.5e-09 38.3 0.2 7.1e-06 26.5 0.2 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPS27443.1 - 8e-09 35.6 0.0 3.4e-08 33.6 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EPS27443.1 - 1e-07 31.5 0.6 0.0035 16.7 0.1 3.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EPS27443.1 - 3.5e-07 30.1 1.5 0.0052 16.4 0.4 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EPS27443.1 - 1.9e-06 27.5 0.1 3.7e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 EPS27443.1 - 4.2e-06 26.4 0.2 8.2e-06 25.4 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EPS27443.1 - 1.5e-05 23.9 0.4 3.3e-05 22.8 0.4 1.6 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 EPS27443.1 - 2.3e-05 23.7 0.1 0.0002 20.6 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 EPS27443.1 - 0.00097 18.5 0.1 0.42 9.9 0.1 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 EPS27443.1 - 0.0011 18.3 0.0 0.0025 17.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 EPS27443.1 - 0.0017 18.8 1.3 1.2 9.6 0.1 3.0 2 0 0 2 2 2 1 Putative NAD(P)-binding GIDA PF01134.22 EPS27443.1 - 0.0075 15.4 0.2 0.0075 15.4 0.2 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 EPS27443.1 - 0.027 13.7 0.3 0.089 12.0 0.1 1.9 2 0 0 2 2 2 0 Thi4 family FMO-like PF00743.19 EPS27443.1 - 0.05 12.0 0.1 1.8 6.9 0.0 2.7 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like NAD_Gly3P_dh_N PF01210.23 EPS27443.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.18 EPS27443.1 - 0.14 12.0 0.3 0.35 10.8 0.3 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 EPS27443.1 - 0.15 11.4 0.7 0.31 10.4 0.0 1.8 2 0 0 2 2 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 EPS27443.1 - 0.16 12.0 1.0 9.2 6.3 0.1 2.8 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain FMN_dh PF01070.18 EPS27443.1 - 0.24 10.4 1.1 0.79 8.7 0.6 2.0 2 0 0 2 2 2 0 FMN-dependent dehydrogenase DUF3128 PF11326.8 EPS27444.1 - 1.3e-25 89.5 2.8 2.3e-25 88.7 2.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) RNA12 PF10443.9 EPS27445.1 - 9e-171 568.5 0.2 5.6e-170 565.9 0.2 2.0 1 1 0 1 1 1 1 RNA12 protein ATPase_2 PF01637.18 EPS27445.1 - 3.5e-07 30.4 0.0 1.8e-06 28.1 0.0 2.1 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea RRM_1 PF00076.22 EPS27445.1 - 3.1e-05 23.7 0.0 9e-05 22.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_16 PF13191.6 EPS27445.1 - 0.0015 19.0 0.0 0.014 15.8 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain DUF2487 PF10673.9 EPS27445.1 - 0.0033 17.5 0.0 0.01 15.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2487) AAA_14 PF13173.6 EPS27445.1 - 0.084 12.9 0.1 3.4 7.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain ScsC_N PF18312.1 EPS27445.1 - 0.16 11.8 4.9 1.6 8.6 0.0 3.5 3 0 0 3 3 3 0 Copper resistance protein ScsC N-terminal domain TIR_2 PF13676.6 EPS27445.1 - 0.18 12.4 0.8 6.8 7.3 0.0 3.5 4 0 0 4 4 4 0 TIR domain p450 PF00067.22 EPS27446.1 - 1.7e-15 56.7 0.0 1e-11 44.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 MMU163 PF17119.5 EPS27447.1 - 2.6e-119 396.9 0.0 3.5e-119 396.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial protein up-regulated during meiosis Mcl1_mid PF12341.8 EPS27448.1 - 1.3e-100 336.6 0.0 2.4e-99 332.4 0.0 2.2 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 EPS27448.1 - 2.5e-17 62.9 1.8 3.3e-06 27.7 0.0 6.9 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS27448.1 - 7.6e-17 61.4 0.2 1.2e-05 25.5 0.1 7.5 2 1 6 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EPS27448.1 - 6e-08 32.1 0.0 6.6e-07 28.7 0.0 2.2 1 1 1 2 2 2 1 Coatomer WD associated region eIF2A PF08662.11 EPS27448.1 - 3.5e-05 23.8 0.1 0.00042 20.3 0.0 2.5 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 EPS27448.1 - 0.0061 16.5 0.3 13 5.9 0.0 4.6 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 EPS27448.1 - 0.014 14.4 0.1 7 5.5 0.0 3.2 1 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Lactonase PF10282.9 EPS27448.1 - 0.024 13.9 0.0 0.41 9.8 0.0 2.6 2 1 0 2 2 2 0 Lactonase, 7-bladed beta-propeller DNA_pol_alpha_N PF12254.8 EPS27448.1 - 0.041 14.0 5.3 0.1 12.7 5.3 1.6 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal Collagen_bind_2 PF12904.7 EPS27448.1 - 0.08 12.9 0.0 0.32 11.0 0.0 2.0 1 0 0 1 1 1 0 Putative collagen-binding domain of a collagenase Cytochrom_D1 PF02239.16 EPS27448.1 - 0.12 10.9 1.4 1.7 7.1 0.4 2.6 3 1 0 3 3 3 0 Cytochrome D1 heme domain PQQ_3 PF13570.6 EPS27448.1 - 0.79 10.3 8.3 69 4.1 0.0 5.2 4 1 0 4 4 4 0 PQQ-like domain Gmad1 PF10647.9 EPS27448.1 - 0.83 9.4 8.7 2.5 7.8 0.5 3.6 3 1 2 5 5 5 0 Lipoprotein LpqB beta-propeller domain ILVD_EDD PF00920.21 EPS27449.1 - 1.4e-159 532.0 0.1 1.6e-159 531.8 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family DAO PF01266.24 EPS27450.1 - 3.1e-33 115.8 0.0 4.1e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EPS27450.1 - 1.9e-06 27.9 0.1 0.016 15.2 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EPS27450.1 - 3.8e-06 26.4 0.1 0.035 13.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EPS27450.1 - 7.5e-06 25.3 0.0 0.00011 21.4 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 EPS27450.1 - 5.5e-05 22.4 0.1 0.057 12.5 0.0 2.4 2 1 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 EPS27450.1 - 0.00042 20.5 0.0 0.0012 19.0 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 EPS27450.1 - 0.00059 18.8 0.3 0.021 13.7 0.2 2.4 2 1 0 2 2 2 1 Tryptophan halogenase Pyr_redox_3 PF13738.6 EPS27450.1 - 0.003 16.9 0.0 0.67 9.1 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EPS27450.1 - 0.0079 14.9 0.0 0.77 8.4 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Het-C PF07217.11 EPS27450.1 - 0.027 13.0 0.0 0.039 12.5 0.0 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C TrkA_N PF02254.18 EPS27450.1 - 0.048 13.9 0.0 0.08 13.2 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Sacchrp_dh_NADP PF03435.18 EPS27450.1 - 0.05 13.9 0.0 3.8 7.8 0.0 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Thi4 PF01946.17 EPS27450.1 - 0.13 11.4 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.16 EPS27450.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA VTC PF09359.10 EPS27451.1 - 8.8e-91 304.1 0.1 1.5e-90 303.3 0.1 1.4 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 EPS27451.1 - 1.7e-13 50.8 3.6 1.7e-13 50.8 3.6 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 EPS27451.1 - 3.6e-05 23.9 26.5 0.00057 19.9 0.1 4.9 2 2 2 5 5 5 3 SPX domain RTA1 PF04479.13 EPS27452.1 - 2.8e-70 236.1 15.4 2.8e-70 236.1 15.4 1.6 2 0 0 2 2 2 1 RTA1 like protein 7TMR-DISM_7TM PF07695.11 EPS27452.1 - 0.003 17.5 20.8 0.022 14.7 8.4 2.5 1 1 0 2 2 2 2 7TM diverse intracellular signalling TMEM100 PF16311.5 EPS27452.1 - 0.17 11.4 1.8 0.31 10.6 0.0 2.2 2 0 0 2 2 2 0 Transmembrane protein 100 Bac_rhamnosid_C PF17390.2 EPS27453.1 - 1.8e-15 56.5 0.1 5e-15 55.1 0.1 1.7 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid6H PF17389.2 EPS27453.1 - 1.3e-07 31.3 0.0 0.00019 20.8 0.0 2.4 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain AA_permease_2 PF13520.6 EPS27455.1 - 3.7e-65 220.4 44.3 4.5e-65 220.1 44.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPS27455.1 - 1.1e-15 57.2 31.9 1.5e-15 56.7 31.9 1.0 1 0 0 1 1 1 1 Amino acid permease PsiE PF06146.12 EPS27456.1 - 0.1 13.0 1.6 0.36 11.2 1.0 2.3 1 1 1 2 2 2 0 Phosphate-starvation-inducible E MFS_1 PF07690.16 EPS27457.1 - 7e-37 127.2 40.6 7.1e-36 123.9 21.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS27457.1 - 1.4e-05 24.2 1.8 1.4e-05 24.2 1.8 2.0 1 1 0 2 2 2 1 Sugar (and other) transporter MFS_5 PF05631.14 EPS27457.1 - 0.00066 18.7 0.9 0.00066 18.7 0.9 1.8 3 0 0 3 3 3 1 Sugar-tranasporters, 12 TM TRI12 PF06609.13 EPS27457.1 - 0.003 16.1 1.2 0.0044 15.5 1.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 EPS27457.1 - 0.9 8.3 6.3 1.5 7.6 3.1 2.6 2 1 0 2 2 2 0 MFS_1 like family Metallophos PF00149.28 EPS27458.1 - 4.4e-09 37.1 1.1 1.3e-08 35.6 1.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EPS27458.1 - 5.6e-07 29.9 0.1 0.0013 19.0 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain APG17 PF04108.12 EPS27459.1 - 0.08 12.0 6.9 0.093 11.8 6.5 1.4 1 1 0 1 1 1 0 Autophagy protein Apg17 DUF4890 PF16231.5 EPS27459.1 - 0.55 10.7 4.9 1.5 9.3 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4890) SurA_N_3 PF13624.6 EPS27459.1 - 0.81 9.5 10.5 0.072 12.9 4.8 2.1 2 0 0 2 2 2 0 SurA N-terminal domain Mod_r PF07200.13 EPS27459.1 - 4.4 7.4 13.7 9.2 6.4 12.9 2.1 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Uso1_p115_C PF04871.13 EPS27459.1 - 6.8 7.1 23.3 0.84 10.0 2.4 3.1 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region CBFD_NFYB_HMF PF00808.23 EPS27460.1 - 3.7e-05 23.9 0.1 5e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-W PF15510.6 EPS27460.1 - 8.5e-05 22.7 0.1 9.2e-05 22.6 0.1 1.1 1 0 0 1 1 1 1 CENP-W protein TAFII28 PF04719.14 EPS27460.1 - 0.013 15.6 0.2 0.022 14.8 0.2 1.3 1 1 0 1 1 1 0 hTAFII28-like protein conserved region NUDIX PF00293.28 EPS27461.1 - 5.3e-11 42.7 0.0 1.7e-10 41.0 0.0 1.8 2 0 0 2 2 2 1 NUDIX domain DSBA PF01323.20 EPS27462.1 - 9.8e-36 123.3 0.0 5.8e-34 117.6 0.0 2.0 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_5 PF13743.6 EPS27462.1 - 0.096 12.4 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_3 PF13192.6 EPS27462.1 - 0.16 12.1 0.0 2.6 8.1 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin domain FMN_dh PF01070.18 EPS27463.1 - 1.7e-109 366.0 0.1 2.1e-109 365.8 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EPS27463.1 - 1e-18 67.2 0.0 2.7e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EPS27463.1 - 4e-06 26.2 0.1 6.7e-06 25.5 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 EPS27463.1 - 5e-05 22.5 0.2 0.00036 19.6 0.0 2.2 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 EPS27463.1 - 0.0072 15.8 0.0 0.12 11.8 0.0 2.2 2 0 0 2 2 2 1 Histidine biosynthesis protein NMO PF03060.15 EPS27463.1 - 0.035 13.5 0.4 0.067 12.6 0.2 1.5 2 0 0 2 2 2 0 Nitronate monooxygenase DUF202 PF02656.15 EPS27464.1 - 0.0042 17.5 9.4 0.034 14.6 9.4 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF202) 6PF2K PF01591.18 EPS27465.1 - 5.6e-70 235.1 0.0 2.3e-49 167.7 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EPS27465.1 - 1.8e-32 112.7 0.0 4e-25 88.6 0.0 2.4 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EPS27465.1 - 6.2e-06 26.4 0.0 0.11 12.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain KTI12 PF08433.10 EPS27465.1 - 0.061 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MFS_1 PF07690.16 EPS27466.1 - 8.2e-13 48.0 27.0 6.7e-09 35.1 10.0 2.9 2 2 0 2 2 2 2 Major Facilitator Superfamily p450 PF00067.22 EPS27467.1 - 2.3e-16 59.6 0.1 3.4e-09 36.0 0.0 2.3 2 0 0 2 2 2 2 Cytochrome P450 Fer2 PF00111.27 EPS27468.1 - 3.1e-07 30.2 3.5 3.1e-07 30.2 3.5 1.7 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain FAD_binding_4 PF01565.23 EPS27469.1 - 8.3e-18 64.5 0.6 1.5e-17 63.6 0.6 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EPS27469.1 - 0.00083 19.4 0.0 0.0021 18.1 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like CaKB PF03185.15 EPS27469.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit Glyco_hydro_3 PF00933.21 EPS27470.1 - 1.8e-52 178.7 0.0 3e-52 178.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 EPS27470.1 - 1.7e-51 175.1 0.0 2.6e-51 174.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 EPS27470.1 - 8.1e-19 67.5 0.5 8.1e-19 67.5 0.5 2.7 2 0 0 2 2 2 1 Fibronectin type III-like domain DUF11 PF01345.18 EPS27470.1 - 0.15 12.4 1.0 0.57 10.5 1.0 1.9 1 1 0 1 1 1 0 Domain of unknown function DUF11 Bin3 PF06859.12 EPS27471.1 - 1.9e-31 108.9 0.0 2.8e-31 108.4 0.0 1.2 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_23 PF13489.6 EPS27471.1 - 9.6e-11 41.8 0.0 1.2e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPS27471.1 - 1.6e-10 41.0 0.0 2e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPS27471.1 - 7.7e-09 36.1 0.0 1.4e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPS27471.1 - 1.4e-07 32.1 0.0 2.6e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS27471.1 - 2.1e-07 31.5 0.0 4.1e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EPS27471.1 - 0.0003 20.4 0.0 0.00091 18.8 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 EPS27471.1 - 0.0032 16.9 0.0 0.0051 16.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 EPS27471.1 - 0.008 16.1 0.0 0.018 15.0 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 EPS27471.1 - 0.15 10.9 0.0 0.19 10.6 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) FPP PF05911.11 EPS27472.1 - 0.00025 19.4 6.2 0.00032 19.0 6.2 1.0 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil Rootletin PF15035.6 EPS27472.1 - 0.0015 18.6 15.1 0.0072 16.4 8.6 2.2 1 1 1 2 2 2 2 Ciliary rootlet component, centrosome cohesion Macoilin PF09726.9 EPS27472.1 - 0.0031 16.1 8.6 0.0037 15.9 8.6 1.1 1 0 0 1 1 1 1 Macoilin family Atg14 PF10186.9 EPS27472.1 - 0.018 14.1 8.7 0.029 13.5 8.7 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Filament PF00038.21 EPS27472.1 - 0.023 14.3 11.7 0.032 13.8 11.7 1.1 1 0 0 1 1 1 0 Intermediate filament protein DUF4201 PF13870.6 EPS27472.1 - 0.034 13.9 10.9 0.05 13.3 10.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) GAS PF13851.6 EPS27472.1 - 0.055 12.8 10.3 0.082 12.3 10.3 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Golgin_A5 PF09787.9 EPS27472.1 - 0.07 12.6 7.9 0.088 12.3 7.9 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 APG6_N PF17675.1 EPS27472.1 - 0.081 13.5 9.8 0.14 12.7 9.8 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF1664 PF07889.12 EPS27472.1 - 0.11 12.6 5.1 0.91 9.6 5.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF2381 PF09544.10 EPS27472.1 - 0.11 12.0 9.5 0.028 13.9 4.1 2.2 1 1 2 3 3 3 0 Protein of unknown function (DUF2381) Spc7 PF08317.11 EPS27472.1 - 0.19 10.5 9.9 0.27 10.1 9.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Uso1_p115_C PF04871.13 EPS27472.1 - 0.36 11.2 10.5 0.43 10.9 9.6 1.6 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region TMPIT PF07851.13 EPS27472.1 - 0.42 9.8 4.5 0.57 9.4 4.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein OmpH PF03938.14 EPS27472.1 - 0.44 10.9 5.1 0.84 10.0 5.1 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Fez1 PF06818.15 EPS27472.1 - 0.61 10.5 12.9 0.66 10.4 11.1 1.8 1 1 1 2 2 2 0 Fez1 FapA PF03961.13 EPS27472.1 - 0.77 8.3 5.8 1 7.9 5.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A YabA PF06156.13 EPS27472.1 - 1.5 9.5 9.8 3.1 8.5 7.7 2.1 1 1 1 2 2 2 0 Initiation control protein YabA UPF0242 PF06785.11 EPS27472.1 - 2.1 8.4 9.8 3 7.9 9.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4845 PF16137.5 EPS27472.1 - 3.8 8.4 5.7 36 5.3 0.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4845) Mto2_bdg PF12808.7 EPS27472.1 - 4.4 7.7 22.0 0.24 11.7 1.1 3.5 2 2 1 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region EMP24_GP25L PF01105.24 EPS27472.1 - 5.2 7.0 7.1 22 5.0 7.1 2.0 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Cauli_VI PF01693.16 EPS27473.1 - 1.3e-36 124.6 2.7 1.4e-17 63.7 0.1 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.24 EPS27473.1 - 4.1e-36 124.3 0.0 6.7e-36 123.6 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.6 EPS27473.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Reverse transcriptase-like Na_H_Exchanger PF00999.21 EPS27474.1 - 8.6e-49 166.3 16.8 1.1e-48 165.9 16.8 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Glyco_hydro_10 PF00331.20 EPS27475.1 - 1.5e-109 366.0 0.7 1.8e-109 365.7 0.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 GFO_IDH_MocA PF01408.22 EPS27476.1 - 2.1e-20 73.8 0.0 3.9e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 EPS27476.1 - 0.019 15.4 0.0 0.041 14.3 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Ge1_WD40 PF16529.5 EPS27477.1 - 0.0073 15.3 0.0 0.02 13.9 0.0 1.7 1 1 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF445 PF04286.12 EPS27477.1 - 0.044 13.6 0.1 0.21 11.3 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF445) Coilin_N PF15862.5 EPS27477.1 - 1.2 9.0 4.0 2.6 7.9 4.0 1.5 1 0 0 1 1 1 0 Coilin N-terminus BC10 PF06726.12 EPS27478.1 - 5.1e-15 55.4 9.6 8.2e-15 54.8 9.6 1.3 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 US22 PF02393.16 EPS27478.1 - 0.11 12.8 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 US22 like Chs7 PF12271.8 EPS27480.1 - 5.3e-115 383.7 2.4 6e-115 383.5 2.4 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Cytochrom_B_C PF00032.17 EPS27480.1 - 1.1 9.5 4.3 0.44 10.9 0.1 2.3 2 1 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD DUF1129 PF06570.11 EPS27480.1 - 1.2 8.6 6.1 0.36 10.3 2.5 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) DLH PF01738.18 EPS27481.1 - 3.8e-28 98.5 0.0 4.7e-28 98.2 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 EPS27481.1 - 0.01 15.8 0.0 0.74 9.7 0.0 2.1 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal LIDHydrolase PF10230.9 EPS27481.1 - 0.038 13.5 0.0 0.049 13.2 0.0 1.1 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Peptidase_S15 PF02129.18 EPS27481.1 - 0.17 11.5 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF5527 PF17665.1 EPS27482.1 - 0.018 14.6 0.1 0.021 14.4 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5527) Popeye PF04831.13 EPS27482.1 - 0.14 12.3 2.5 0.17 12.1 2.5 1.1 1 0 0 1 1 1 0 Popeye protein conserved region ERG4_ERG24 PF01222.17 EPS27483.1 - 6.9e-141 469.9 22.3 8.1e-141 469.7 22.3 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family zf-C3HC4 PF00097.25 EPS27484.1 - 2.7e-07 30.3 3.9 5.8e-07 29.3 3.9 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EPS27484.1 - 8.7e-07 28.7 4.6 2.8e-05 23.8 2.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EPS27484.1 - 1e-06 28.9 4.7 0.00011 22.5 1.8 2.3 2 0 0 2 2 2 2 Ring finger domain zf-RING_UBOX PF13445.6 EPS27484.1 - 1.2e-05 25.2 4.5 1.2e-05 25.2 4.5 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EPS27484.1 - 1.3e-05 25.2 4.5 0.0001 22.4 5.1 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EPS27484.1 - 6.9e-05 22.6 7.4 0.0002 21.2 7.4 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EPS27484.1 - 0.00014 21.7 5.7 0.00036 20.4 5.7 1.7 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EPS27484.1 - 0.27 11.2 10.4 4.3 7.3 10.5 2.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 EPS27484.1 - 0.34 11.1 2.0 0.74 10.0 2.0 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 EPS27484.1 - 1.2 8.9 5.8 8 6.3 3.5 2.6 2 1 0 2 2 2 0 RING-like zinc finger UCH PF00443.29 EPS27485.1 - 5.2e-46 157.2 0.0 8.6e-46 156.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EPS27485.1 - 2.3e-10 40.6 0.0 7.2e-07 29.1 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase SPX PF03105.19 EPS27485.1 - 2.3 8.1 8.4 0.31 10.9 2.6 2.1 2 0 0 2 2 2 0 SPX domain dCMP_cyt_deam_1 PF00383.23 EPS27486.1 - 1.3e-05 25.0 0.6 0.053 13.4 0.0 2.7 2 1 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EPS27486.1 - 0.14 11.9 0.5 8.6 6.1 0.2 2.3 2 0 0 2 2 2 0 MafB19-like deaminase Cyclin PF08613.11 EPS27488.1 - 5.2e-32 111.5 0.1 1e-31 110.5 0.1 1.6 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EPS27488.1 - 3.6e-05 23.5 0.0 6.2e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Arm PF00514.23 EPS27489.1 - 3.3e-16 58.7 17.0 0.00033 20.6 0.0 9.9 13 0 0 13 13 13 3 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EPS27489.1 - 2.7e-06 27.8 14.0 0.22 12.1 0.0 7.3 8 0 0 8 8 8 2 HEAT-like repeat HEAT_2 PF13646.6 EPS27489.1 - 8.3e-06 26.1 8.5 0.84 10.1 0.0 7.0 6 2 1 7 7 7 3 HEAT repeats HEAT PF02985.22 EPS27489.1 - 0.0014 18.7 14.4 0.13 12.6 0.0 7.3 8 0 0 8 8 8 1 HEAT repeat V-ATPase_H_N PF03224.14 EPS27489.1 - 0.0033 16.8 0.0 0.14 11.5 0.0 3.2 3 2 0 3 3 3 1 V-ATPase subunit H Fructosamin_kin PF03881.14 EPS27490.1 - 1.9e-77 260.3 0.0 2.3e-77 260.1 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.23 EPS27490.1 - 2.7e-10 40.6 0.5 4.3e-10 39.9 0.5 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EPS27490.1 - 0.23 10.3 0.0 0.33 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) GST_N_2 PF13409.6 EPS27491.1 - 1.1e-20 73.7 0.2 3e-20 72.3 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EPS27491.1 - 1.2e-20 73.7 0.2 2.1e-20 72.9 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EPS27491.1 - 4.3e-11 43.0 0.1 7.9e-11 42.2 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EPS27491.1 - 1e-05 25.5 0.5 3.2e-05 23.9 0.4 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EPS27491.1 - 0.0067 16.6 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 EPS27491.1 - 0.16 12.2 0.0 0.36 11.1 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin GST_C_5 PF16865.5 EPS27491.1 - 0.19 12.3 0.0 0.37 11.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Cyclin_N PF00134.23 EPS27492.1 - 8.8e-10 38.4 0.0 7.5e-09 35.4 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain CTP_transf_1 PF01148.20 EPS27493.1 - 6.3e-82 275.3 23.1 7.8e-82 275.0 23.1 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF3636 PF12331.8 EPS27494.1 - 9.2e-48 161.8 0.1 1.5e-47 161.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) LCD1 PF09798.9 EPS27494.1 - 2.4e-06 26.4 1.1 0.02 13.4 0.6 3.3 2 2 1 3 3 3 2 DNA damage checkpoint protein DUF2046 PF09755.9 EPS27494.1 - 0.004 16.4 8.5 0.0086 15.3 8.5 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) DUF4461 PF14688.6 EPS27494.1 - 0.063 13.1 0.8 0.1 12.3 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4461) DUF1192 PF06698.11 EPS27494.1 - 0.49 10.5 5.5 3.5 7.8 1.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Fmp27_WPPW PF10359.9 EPS27494.1 - 1 8.2 6.3 1.5 7.6 6.3 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain CSN5_C PF18323.1 EPS27494.1 - 1.1 10.2 4.0 4 8.4 4.0 1.9 1 0 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain DUF3584 PF12128.8 EPS27494.1 - 1.3 6.4 13.1 1.8 5.9 13.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FUSC PF04632.12 EPS27494.1 - 1.4 7.4 9.7 11 4.4 7.9 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein family Atg14 PF10186.9 EPS27494.1 - 5.4 6.0 6.8 8.6 5.3 6.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 S4 PF01479.25 EPS27495.1 - 2.5e-15 55.9 0.3 7.9e-15 54.3 0.0 2.0 2 0 0 2 2 2 1 S4 domain Glyco_hydro_11 PF00457.17 EPS27495.1 - 0.044 13.4 0.5 0.078 12.6 0.5 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 11 FUSC PF04632.12 EPS27495.1 - 0.72 8.3 4.9 0.92 8.0 4.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family SPG4 PF17325.2 EPS27495.1 - 2.6 9.2 6.6 1.5 9.9 0.5 2.5 2 0 0 2 2 2 0 Stationary phase protein 4 Mitofilin PF09731.9 EPS27496.1 - 6.7 5.4 10.2 12 4.6 10.2 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein E1_dh PF00676.20 EPS27497.1 - 1.6e-113 378.7 0.4 1.9e-113 378.4 0.4 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 EPS27497.1 - 0.00085 18.6 0.0 0.0015 17.8 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase PH_10 PF15411.6 EPS27500.1 - 5.7e-27 94.4 0.0 1e-26 93.6 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA PF00092.28 EPS27500.1 - 1.5e-12 48.2 0.0 2.4e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 EPS27500.1 - 1.8e-10 40.9 0.1 3.1e-09 37.0 0.1 2.7 2 1 0 2 2 2 1 von Willebrand factor type A domain zf-RING_2 PF13639.6 EPS27500.1 - 0.00012 22.3 5.5 0.00023 21.4 5.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EPS27500.1 - 0.0025 17.7 5.9 0.0046 16.9 5.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EPS27500.1 - 0.0055 17.0 2.6 0.013 15.8 2.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 EPS27500.1 - 0.008 15.8 3.1 0.008 15.8 3.1 1.8 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 EPS27500.1 - 0.0092 15.8 4.4 0.018 14.9 4.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PH PF00169.29 EPS27500.1 - 0.012 16.1 0.0 0.035 14.6 0.0 1.7 1 0 0 1 1 1 0 PH domain zf-C3HC4 PF00097.25 EPS27500.1 - 0.037 13.9 5.3 0.077 12.9 5.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EPS27500.1 - 0.041 13.8 2.2 0.08 12.8 2.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 EPS27500.1 - 0.042 14.2 4.7 0.078 13.3 4.7 1.5 1 0 0 1 1 1 0 RING-like domain DUF1147 PF06615.11 EPS27500.1 - 0.056 13.5 0.6 0.12 12.5 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) zf-RING_11 PF17123.5 EPS27500.1 - 0.088 12.6 3.7 0.19 11.5 3.7 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-C3H2C3 PF17122.5 EPS27500.1 - 0.52 10.4 5.7 1.2 9.2 5.7 1.7 1 1 0 1 1 1 0 Zinc-finger Peptidase_M48 PF01435.18 EPS27501.1 - 1.8e-34 119.3 0.0 3.8e-34 118.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M48 Cpn60_TCP1 PF00118.24 EPS27502.1 - 5.9e-150 500.1 6.4 6.7e-150 500.0 6.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ribosomal_L12 PF00542.19 EPS27503.1 - 1.4e-20 73.4 8.2 8.4e-20 70.9 6.4 2.3 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 EPS27503.1 - 2.2e-12 46.5 9.7 2.2e-12 46.5 9.7 3.5 4 1 0 4 4 4 1 Ribosomal protein L7/L12 dimerisation domain Bac_DNA_binding PF00216.21 EPS27503.1 - 0.047 13.9 0.7 0.093 12.9 0.7 1.5 1 0 0 1 1 1 0 Bacterial DNA-binding protein DUF3613 PF12266.8 EPS27504.1 - 0.035 13.9 1.6 0.091 12.5 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3613) Velvet PF11754.8 EPS27505.1 - 4.1e-57 194.0 0.0 5.2e-33 115.0 0.0 2.0 1 1 1 2 2 2 2 Velvet factor Methyltr_RsmF_N PF17125.5 EPS27506.1 - 0.16 12.5 0.0 0.16 12.4 0.0 1.1 1 0 0 1 1 1 0 N-terminal domain of 16S rRNA methyltransferase RsmF NUFIP2 PF15293.6 EPS27507.1 - 0.091 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 2 SYF2 PF08231.12 EPS27508.1 - 4.8e-58 196.1 15.9 4.8e-58 196.1 15.9 1.9 2 0 0 2 2 2 1 SYF2 splicing factor NAD_binding_10 PF13460.6 EPS27509.1 - 1.2e-07 31.8 0.0 1.2e-06 28.6 0.0 2.2 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EPS27509.1 - 5.3e-06 26.1 0.0 8.7e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EPS27509.1 - 0.0001 21.4 0.0 0.0003 19.9 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EPS27509.1 - 0.0051 15.9 0.0 0.049 12.7 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain adh_short PF00106.25 EPS27509.1 - 0.007 15.8 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase 3HCDH_N PF02737.18 EPS27509.1 - 0.034 14.0 0.0 2.5 7.9 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain KR PF08659.10 EPS27509.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 KR domain YEATS PF03366.16 EPS27510.1 - 6.1e-36 122.2 1.4 1e-35 121.6 1.4 1.3 1 0 0 1 1 1 1 YEATS family M16C_assoc PF08367.11 EPS27510.1 - 0.049 12.8 1.5 0.068 12.3 1.5 1.2 1 0 0 1 1 1 0 Peptidase M16C associated IDO PF01231.18 EPS27511.1 - 7.2e-153 509.4 0.0 8.1e-153 509.3 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.11 EPS27511.1 - 0.01 14.6 0.0 0.029 13.1 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1864) Aminotran_5 PF00266.19 EPS27512.1 - 2e-07 30.3 0.0 1e-05 24.7 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EPS27512.1 - 0.0057 16.0 0.0 0.0094 15.3 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Fungal_trans PF04082.18 EPS27513.1 - 1.9e-11 43.5 0.1 5.1e-11 42.1 0.1 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS27513.1 - 1.5e-08 34.6 10.5 2.9e-08 33.7 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SWC7 PF17330.2 EPS27513.1 - 0.017 15.1 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 Epsilon_antitox PF08998.11 EPS27513.1 - 0.18 12.1 0.3 0.47 10.7 0.0 1.8 2 0 0 2 2 2 0 Bacterial epsilon antitoxin COX7a PF02238.15 EPS27514.1 - 2.7e-23 82.1 3.7 3.5e-23 81.7 3.7 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII PI-PLC-X PF00388.19 EPS27516.1 - 0.18 11.4 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Ins_P5_2-kin PF06090.12 EPS27517.1 - 2.5e-43 148.8 0.1 1.1e-42 146.7 0.1 1.8 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Oxidored_molyb PF00174.19 EPS27518.1 - 4.1e-57 192.5 0.0 7.7e-57 191.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EPS27518.1 - 1.4e-37 128.8 0.4 3.8e-37 127.4 0.4 1.7 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.24 EPS27518.1 - 6.1e-23 81.0 0.0 1.1e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EPS27518.1 - 1.2e-22 80.6 1.9 3.3e-22 79.2 0.0 2.8 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 EPS27518.1 - 7.5e-15 54.8 0.0 1.9e-14 53.5 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 EPS27518.1 - 0.0042 17.2 0.7 0.26 11.4 0.0 3.3 2 1 0 3 3 3 1 Ferric reductase NAD binding domain Molybdopterin PF00384.22 EPS27519.1 - 1.2e-67 228.8 0.0 1.6e-67 228.4 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.21 EPS27519.1 - 7.5e-25 87.1 0.0 1.5e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.16 EPS27519.1 - 4.7e-12 45.7 0.3 1.9e-11 43.7 0.2 2.1 2 0 0 2 2 2 1 Molybdopterin oxidoreductase Fe4S4 domain NTP_transf_3 PF12804.7 EPS27520.1 - 2.7e-18 66.8 0.0 5e-18 66.0 0.0 1.4 1 1 0 1 1 1 1 MobA-like NTP transferase domain MoeA_N PF03453.17 EPS27521.1 - 7.4e-33 113.5 0.0 1.1e-32 113.0 0.0 1.3 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 EPS27521.1 - 1.7e-24 86.1 0.0 2.9e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain NUDIX PF00293.28 EPS27522.1 - 5.5e-23 81.4 0.1 6.2e-23 81.3 0.1 1.0 1 0 0 1 1 1 1 NUDIX domain LOR PF04525.12 EPS27523.1 - 0.00045 19.9 0.0 0.0015 18.2 0.0 1.8 1 1 0 1 1 1 1 LURP-one-related Acetyltransf_3 PF13302.7 EPS27525.1 - 4.6e-27 95.4 0.0 7.9e-27 94.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPS27525.1 - 1.6e-07 31.6 0.0 3e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 EPS27525.1 - 5.6e-06 26.1 0.0 9.8e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPS27525.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Polysacc_deac_1 PF01522.21 EPS27527.1 - 8.9e-23 80.5 0.1 1.5e-22 79.8 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Novirhabdo_Nv PF05554.11 EPS27527.1 - 0.012 15.3 0.1 0.07 12.9 0.0 2.1 2 0 0 2 2 2 0 Viral hemorrhagic septicemia virus non-virion protein DUF1682 PF07946.14 EPS27528.1 - 2.7e-112 375.1 4.4 3.2e-112 374.9 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Haspin_kinase PF12330.8 EPS27531.1 - 6.8e-40 137.1 0.0 1e-39 136.6 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Med20 PF08612.11 EPS27532.1 - 4.9e-78 261.6 0.0 5.7e-78 261.4 0.0 1.0 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Med3 PF11593.8 EPS27532.1 - 0.2 10.8 6.0 0.29 10.3 6.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal EF-hand_1 PF00036.32 EPS27533.1 - 1.3e-41 137.0 11.6 7.8e-10 37.6 0.9 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EPS27533.1 - 3.6e-36 123.4 5.3 3.9e-19 68.9 2.2 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EPS27533.1 - 1.9e-34 117.3 11.5 2.4e-15 56.1 0.6 4.0 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 EPS27533.1 - 3.8e-30 101.2 8.5 7.1e-09 34.9 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EPS27533.1 - 6.8e-26 88.6 9.8 4.7e-06 25.9 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EPS27533.1 - 1.4e-16 60.5 0.4 2.3e-09 37.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EPS27533.1 - 6.8e-10 38.8 1.6 0.00078 19.4 0.3 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EPS27533.1 - 5.9e-09 36.2 0.2 0.0016 18.7 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.13 EPS27533.1 - 1e-06 28.6 0.1 0.008 16.2 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 EPS27533.1 - 6.4e-06 26.2 1.6 2.3e-05 24.4 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_11 PF08976.11 EPS27533.1 - 9.4e-05 23.2 0.2 0.0025 18.6 0.1 2.0 1 1 1 2 2 2 1 EF-hand domain TerB PF05099.13 EPS27533.1 - 0.00013 21.9 0.3 0.35 10.8 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.13 EPS27533.1 - 0.00059 19.8 1.6 0.52 10.2 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein RNA_pol_Rpb4 PF03874.16 EPS27533.1 - 0.00062 20.1 0.7 0.66 10.3 0.1 2.6 2 1 1 3 3 3 2 RNA polymerase Rpb4 Dockerin_1 PF00404.18 EPS27533.1 - 0.0053 16.9 7.0 0.38 11.0 0.8 2.9 1 1 2 3 3 3 2 Dockerin type I domain DUF5580 PF17743.1 EPS27533.1 - 0.0057 15.3 0.0 0.0058 15.2 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) SurA_N_2 PF13623.6 EPS27533.1 - 0.0084 16.0 0.7 0.32 10.9 0.1 2.2 1 1 1 2 2 2 1 SurA N-terminal domain EF-hand_14 PF17959.1 EPS27533.1 - 0.012 16.0 0.5 6.2 7.2 0.1 2.4 1 1 1 2 2 2 0 EF-hand domain Poly_export PF02563.16 EPS27533.1 - 0.023 14.9 0.0 0.18 12.0 0.0 2.5 2 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein RuvA_C PF07499.13 EPS27533.1 - 0.058 13.9 0.1 8.5 6.9 0.0 3.0 3 0 0 3 3 3 0 RuvA, C-terminal domain dCache_2 PF08269.11 EPS27533.1 - 0.061 12.5 0.1 1 8.5 0.1 2.1 1 1 1 2 2 2 0 Cache domain MotA_activ PF09114.10 EPS27533.1 - 0.061 13.5 0.3 0.91 9.7 0.0 2.3 1 1 0 2 2 2 0 Transcription factor MotA, activation domain DUF4497 PF14924.6 EPS27533.1 - 0.092 13.2 0.0 8.7 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) RloB PF13707.6 EPS27533.1 - 0.11 12.7 1.3 0.72 10.0 0.2 2.1 1 1 1 2 2 2 0 RloB-like protein DUF5132 PF17195.4 EPS27533.1 - 0.16 12.1 0.5 21 5.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) SNARE PF05739.19 EPS27534.1 - 7.2e-16 57.9 0.8 1.7e-15 56.8 0.8 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 EPS27534.1 - 2.5e-05 24.0 8.3 2.5e-05 24.0 8.3 2.2 2 1 0 2 2 2 1 Syntaxin DUF3357 PF11837.8 EPS27534.1 - 0.016 15.6 1.0 0.029 14.8 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) DASH_Dad4 PF08650.10 EPS27534.1 - 0.024 14.6 1.0 0.089 12.8 0.2 2.3 2 1 0 2 2 2 0 DASH complex subunit Dad4 HlyD_D4 PF16572.5 EPS27534.1 - 0.11 12.4 0.1 0.32 10.9 0.1 1.8 1 0 0 1 1 1 0 Long alpha hairpin domain of cation efflux system protein, CusB ZapA PF05164.13 EPS27534.1 - 0.11 12.9 3.3 0.13 12.7 0.1 2.5 3 0 0 3 3 3 0 Cell division protein ZapA MCPsignal PF00015.21 EPS27534.1 - 0.14 12.0 7.1 0.086 12.7 1.6 2.6 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain FliD_C PF07195.12 EPS27534.1 - 0.32 10.4 5.3 1.1 8.6 0.1 2.2 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus FAM76 PF16046.5 EPS27534.1 - 0.58 9.5 2.2 0.92 8.8 2.2 1.3 1 0 0 1 1 1 0 FAM76 protein CTD_bind PF04818.13 EPS27535.1 - 1.3e-17 64.4 0.1 3.4e-17 63.0 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CTK3 PF12243.8 EPS27535.1 - 0.076 13.0 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 Clathrin_lg_ch PF01086.17 EPS27536.1 - 3.1e-74 249.9 5.2 3.4e-74 249.8 5.2 1.0 1 0 0 1 1 1 1 Clathrin light chain CDC37_N PF03234.14 EPS27537.1 - 2.9e-49 167.3 4.2 2.9e-49 167.3 4.2 2.8 3 1 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 EPS27537.1 - 1.3e-42 144.4 0.0 4.5e-42 142.7 0.0 2.0 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 EPS27537.1 - 2.3e-35 120.7 2.5 8.4e-35 118.9 2.5 2.0 1 0 0 1 1 1 1 Cdc37 C terminal domain MecA_N PF05223.11 EPS27537.1 - 0.016 15.5 0.8 0.016 15.5 0.8 2.3 3 0 0 3 3 3 0 NTF2-like N-terminal transpeptidase domain Nckap1 PF09735.9 EPS27537.1 - 0.029 12.4 0.3 1.9 6.4 0.0 2.1 2 0 0 2 2 2 0 Membrane-associated apoptosis protein FliG_C PF01706.16 EPS27537.1 - 0.042 14.1 0.4 0.4 10.9 0.1 2.5 2 0 0 2 2 2 0 FliG C-terminal domain T3SchapCesA PF11439.8 EPS27537.1 - 0.067 13.3 0.2 0.34 11.1 0.0 2.3 2 0 0 2 2 2 0 Type III secretion system filament chaperone CesA EF-G-binding_N PF07299.11 EPS27537.1 - 0.37 11.3 4.7 0.6 10.7 0.5 3.3 2 2 0 2 2 2 0 Elongation factor G-binding protein, N-terminal Cytochrom_B562 PF07361.11 EPS27537.1 - 0.41 11.3 6.5 3.2 8.5 0.6 3.5 2 1 1 3 3 3 0 Cytochrome b562 ABC_membrane PF00664.23 EPS27538.1 - 8.4e-52 176.5 9.3 1.1e-51 176.2 9.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EPS27538.1 - 1.4e-35 122.7 0.0 3e-35 121.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EPS27538.1 - 1.8e-05 24.3 0.0 0.00063 19.3 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EPS27538.1 - 0.016 15.0 0.1 0.041 13.6 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EPS27538.1 - 0.021 15.2 0.1 0.1 13.0 0.1 2.1 2 1 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.6 EPS27538.1 - 0.054 13.2 0.0 0.28 10.9 0.0 2.1 1 1 1 2 2 2 0 AAA domain SbcCD_C PF13558.6 EPS27538.1 - 0.1 12.9 0.6 1.3 9.3 0.6 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 EPS27538.1 - 0.12 12.7 0.3 0.95 9.7 0.3 2.3 1 1 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 EPS27538.1 - 0.18 10.6 0.7 0.38 9.5 0.1 1.7 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Yip1 PF04893.17 EPS27538.1 - 4.5 7.0 14.3 3.1 7.5 1.4 3.0 3 0 0 3 3 3 0 Yip1 domain APH PF01636.23 EPS27539.1 - 1.9e-08 34.5 0.0 0.0015 18.6 0.0 2.4 1 1 0 2 2 2 2 Phosphotransferase enzyme family GFA PF04828.14 EPS27540.1 - 4e-24 84.8 0.0 5.2e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nucleoside_tran PF01733.18 EPS27541.1 - 1e-47 163.0 17.6 2.1e-45 155.5 17.6 2.3 1 1 0 1 1 1 1 Nucleoside transporter MFS_1 PF07690.16 EPS27541.1 - 0.00028 19.9 41.5 0.091 11.7 10.0 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM132D_C PF15706.5 EPS27541.1 - 0.58 10.0 2.1 1.9 8.3 0.0 2.8 3 1 1 4 4 4 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Glyco_hydro_47 PF01532.20 EPS27542.1 - 1.4e-178 594.6 0.0 1.6e-178 594.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 LSM PF01423.22 EPS27543.1 - 1.4e-20 72.8 0.0 1.5e-20 72.6 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EPS27543.1 - 0.00058 19.9 0.0 0.00069 19.7 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 EPS27543.1 - 0.0036 17.4 0.1 0.0041 17.2 0.1 1.1 1 0 0 1 1 1 1 Scd6-like Sm domain IceA2 PF05862.11 EPS27543.1 - 0.093 12.7 0.3 0.18 11.7 0.1 1.6 1 1 0 1 1 1 0 Helicobacter pylori IceA2 protein Rad60-SLD PF11976.8 EPS27544.1 - 2.4e-20 72.1 0.1 4.6e-19 68.0 0.0 2.5 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EPS27544.1 - 1.1e-07 31.5 0.1 9.9e-07 28.4 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin family Trm112p PF03966.16 EPS27545.1 - 1.3e-14 54.5 0.0 1.6e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Trm112p-like protein Zn_ribbon_recom PF13408.6 EPS27545.1 - 0.027 15.0 0.3 0.053 14.1 0.3 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain N-SET PF11764.8 EPS27546.1 - 1.2e-56 191.6 0.4 2.6e-56 190.4 0.4 1.6 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.8 EPS27546.1 - 1.6e-26 91.7 0.8 4e-26 90.4 0.8 1.7 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.28 EPS27546.1 - 3.4e-20 73.1 2.2 1.1e-19 71.5 0.2 2.8 3 0 0 3 3 3 1 SET domain RRM_1 PF00076.22 EPS27546.1 - 0.0026 17.5 0.0 0.0053 16.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SIS PF01380.22 EPS27547.1 - 1.8e-59 199.3 0.0 1.7e-31 108.7 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 EPS27547.1 - 2.9e-17 63.1 0.0 5.5e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EPS27547.1 - 1e-10 41.6 0.0 2.2e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 EPS27547.1 - 0.00076 18.5 0.0 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II DMRL_synthase PF00885.19 EPS27548.1 - 4.4e-57 191.9 0.1 5.2e-57 191.6 0.1 1.1 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase DUF2561 PF10812.8 EPS27548.1 - 0.0092 16.0 0.0 0.013 15.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2561) Proteasome PF00227.26 EPS27549.1 - 2e-46 157.9 1.7 1.2e-32 112.9 0.0 2.7 3 0 0 3 3 3 2 Proteasome subunit Proteasome_A_N PF10584.9 EPS27549.1 - 5.3e-12 45.2 1.0 6.3e-12 44.9 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Elf1 PF05129.13 EPS27550.1 - 0.16 12.1 0.2 0.29 11.2 0.2 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Iso_dh PF00180.20 EPS27551.1 - 2.6e-84 283.3 0.0 3.2e-84 283.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase WBS_methylT PF12589.8 EPS27553.1 - 1.3e-15 57.9 3.8 2.3e-15 57.1 3.8 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 EPS27553.1 - 1e-10 42.1 0.0 1.9e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPS27553.1 - 1.7e-10 41.5 0.0 5.3e-10 39.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPS27553.1 - 8.9e-05 23.2 0.0 0.00024 21.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPS27553.1 - 0.00038 20.3 0.0 0.00058 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EPS27553.1 - 0.0011 18.8 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 EPS27553.1 - 0.0045 16.4 0.0 0.018 14.4 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EPS27553.1 - 0.016 15.1 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 EPS27553.1 - 0.073 12.3 0.0 0.82 8.9 0.0 2.0 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase MTS PF05175.14 EPS27553.1 - 0.17 11.4 0.0 0.39 10.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase small domain Erv26 PF04148.13 EPS27554.1 - 7.9e-98 326.3 1.9 8.9e-98 326.1 1.9 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 Cytochrom_C_asm PF01578.20 EPS27554.1 - 0.0028 17.4 0.5 0.0049 16.7 0.1 1.7 2 0 0 2 2 2 1 Cytochrome C assembly protein DUF1970 PF09301.10 EPS27554.1 - 0.12 12.7 0.8 0.58 10.4 0.8 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF1970) RhoGAP PF00620.27 EPS27555.1 - 1e-41 142.3 0.1 2e-41 141.4 0.1 1.4 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 EPS27555.1 - 1.1e-14 54.8 0.0 2.2e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EPS27555.1 - 0.00017 22.0 0.0 0.00057 20.3 0.0 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 EPS27555.1 - 0.0074 16.6 0.0 0.17 12.2 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain DUF3450 PF11932.8 EPS27555.1 - 0.017 14.4 1.8 0.033 13.5 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) MDM31_MDM32 PF08118.11 EPS27556.1 - 1.1e-248 826.3 0.0 1.5e-248 825.8 0.0 1.2 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Ribosomal_60s PF00428.19 EPS27556.1 - 0.063 13.9 2.0 0.2 12.2 2.0 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein FAM199X PF15814.5 EPS27556.1 - 0.16 11.0 2.0 0.29 10.1 2.0 1.3 1 0 0 1 1 1 0 Protein family FAM199X KH_8 PF17903.1 EPS27557.1 - 0.00019 21.4 0.0 0.0004 20.4 0.0 1.5 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 EPS27557.1 - 0.022 14.6 1.0 0.048 13.5 1.0 1.5 1 0 0 1 1 1 0 KH domain Proteasome PF00227.26 EPS27558.1 - 4.3e-33 114.4 0.1 1.7e-32 112.4 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit HCNGP PF07818.13 EPS27559.1 - 1.4e-31 109.0 0.2 2e-31 108.5 0.2 1.2 1 0 0 1 1 1 1 HCNGP-like protein Clathrin_H_link PF13838.6 EPS27559.1 - 0.18 11.8 0.0 1.3 9.0 0.0 2.2 2 0 0 2 2 2 0 Clathrin-H-link Proteasome PF00227.26 EPS27560.1 - 2.8e-27 95.4 0.0 3.4e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit FAA_hydrolase PF01557.18 EPS27561.1 - 8.2e-63 212.0 0.0 1e-62 211.7 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family GspH PF12019.8 EPS27561.1 - 0.018 15.4 0.1 0.03 14.8 0.1 1.4 1 0 0 1 1 1 0 Type II transport protein GspH HSP20 PF00011.21 EPS27562.1 - 2.1e-16 59.9 0.5 2.1e-12 47.1 0.1 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EPS27562.1 - 8.4e-06 25.3 0.0 0.0095 15.5 0.0 2.3 2 0 0 2 2 2 2 HSP20-like domain found in ArsA Hid1 PF12722.7 EPS27562.1 - 2.4 6.2 7.7 3.3 5.7 7.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ndc1_Nup PF09531.10 EPS27562.1 - 8 5.0 8.6 1.1 7.9 3.7 1.8 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Chorion_2 PF03964.15 EPS27563.1 - 1.5 9.7 9.0 6.4 7.7 5.2 3.0 2 0 0 2 2 2 0 Chorion family 2 Autophagy_act_C PF03987.15 EPS27564.1 - 1.7e-12 47.7 0.8 3.1e-12 46.9 0.8 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain RRM_1 PF00076.22 EPS27565.1 - 2.2e-09 37.0 0.1 5.3e-09 35.8 0.1 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EPS27565.1 - 3.6e-05 23.3 0.0 5.1e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EPS27565.1 - 0.0015 18.3 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif WD40 PF00400.32 EPS27566.1 - 2.1e-17 63.2 14.5 8.2e-05 23.3 0.1 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS27566.1 - 1.2e-06 28.7 0.0 0.024 14.9 0.0 4.6 5 1 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EPS27566.1 - 0.0055 16.6 0.2 1.4 8.9 0.1 2.9 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat Pkinase PF00069.25 EPS27567.1 - 1.8e-61 207.8 0.0 2.4e-61 207.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS27567.1 - 5.2e-29 101.3 0.0 7.6e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EPS27567.1 - 5e-07 29.3 0.1 8.7e-07 28.5 0.1 1.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EPS27567.1 - 6.6e-06 25.3 0.0 9.1e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EPS27567.1 - 0.00025 20.5 0.0 0.00035 20.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EPS27567.1 - 0.0032 17.4 0.2 0.014 15.3 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EPS27567.1 - 0.0038 16.8 0.1 0.0057 16.3 0.1 1.3 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 EPS27567.1 - 0.012 15.3 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pox_ser-thr_kin PF05445.11 EPS27567.1 - 0.018 14.0 0.4 0.025 13.6 0.4 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.11 EPS27567.1 - 0.042 12.9 0.2 0.11 11.6 0.1 1.6 1 1 1 2 2 2 0 Seadornavirus VP7 Fungal_trans PF04082.18 EPS27569.1 - 2.3e-20 72.8 3.4 3.9e-20 72.0 3.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS27569.1 - 3.8e-08 33.3 5.5 8.1e-08 32.3 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.24 EPS27570.1 - 3.2e-38 131.8 21.6 7e-23 81.2 4.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EPS27570.1 - 1.1e-18 67.4 35.7 6.1e-13 48.4 14.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FPN1 PF06963.12 EPS27570.1 - 2 6.9 8.3 1.7 7.2 0.8 2.8 3 1 0 3 3 3 0 Ferroportin1 (FPN1) Melibiase_2 PF16499.5 EPS27571.1 - 9.7e-65 218.5 6.6 2.2e-64 217.4 6.6 1.6 1 1 0 1 1 1 1 Alpha galactosidase A CBM_1 PF00734.18 EPS27571.1 - 1.2e-13 50.8 14.2 5.1e-13 48.7 14.2 2.2 1 0 0 1 1 1 1 Fungal cellulose binding domain Melibiase_C PF17801.1 EPS27571.1 - 1e-09 38.3 0.2 5.6e-09 35.9 0.2 2.2 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 EPS27571.1 - 6e-05 22.1 0.2 0.00035 19.6 0.1 1.9 2 0 0 2 2 2 1 Melibiase Lipase_3 PF01764.25 EPS27572.1 - 5.6e-29 100.8 0.0 3.1e-28 98.4 0.0 2.0 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 EPS27572.1 - 0.00091 19.9 0.2 0.0016 19.1 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPS27572.1 - 0.0017 17.7 0.0 0.0027 17.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EPS27572.1 - 0.0077 16.0 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF2974 PF11187.8 EPS27572.1 - 0.035 13.7 0.0 0.34 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) DUF676 PF05057.14 EPS27572.1 - 0.06 12.8 0.0 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) UPF0227 PF05728.12 EPS27572.1 - 0.062 13.2 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Esterase PF00756.20 EPS27572.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative esterase WW PF00397.26 EPS27573.1 - 1.1e-11 44.5 0.6 2.7e-11 43.4 0.6 1.7 1 0 0 1 1 1 1 WW domain GREB1 PF15782.5 EPS27573.1 - 3.6 4.6 8.4 4.9 4.1 8.4 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Fungal_trans_2 PF11951.8 EPS27574.1 - 2.5e-15 56.2 6.5 3.6e-15 55.7 6.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS27574.1 - 9e-09 35.3 7.7 1.4e-08 34.7 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ecm29 PF13001.7 EPS27576.1 - 9.5e-163 542.4 0.0 1.8e-161 538.2 0.0 2.8 3 1 0 3 3 3 1 Proteasome stabiliser Vac14_Fab1_bd PF12755.7 EPS27576.1 - 5.8e-07 30.0 0.0 0.0087 16.6 0.1 5.1 4 2 2 6 6 6 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 EPS27576.1 - 1.5e-05 24.8 15.2 3 8.3 0.1 10.1 12 0 0 12 12 12 2 HEAT repeat HEAT_EZ PF13513.6 EPS27576.1 - 0.0013 19.2 16.7 9 6.9 0.0 9.9 11 0 0 11 11 11 2 HEAT-like repeat DUF3385 PF11865.8 EPS27576.1 - 0.092 12.6 0.1 2.9 7.8 0.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF3385) MMS19_C PF12460.8 EPS27576.1 - 5.3 6.1 8.2 22 4.0 1.2 4.1 4 1 1 5 5 5 0 RNAPII transcription regulator C-terminal SNF2_N PF00176.23 EPS27577.1 - 7.5e-62 209.1 0.0 1.8e-61 207.8 0.0 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.6 EPS27577.1 - 2.7e-09 36.7 6.8 6.5e-09 35.5 6.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EPS27577.1 - 3e-09 36.6 8.9 7.9e-09 35.2 8.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPS27577.1 - 2e-08 34.0 8.8 4.5e-08 32.8 8.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EPS27577.1 - 1e-06 28.9 10.9 2.3e-06 27.8 10.9 1.6 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 EPS27577.1 - 1.5e-05 24.8 7.2 4.2e-05 23.3 7.2 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EPS27577.1 - 2.5e-05 24.2 3.0 2.5e-05 24.2 3.0 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 EPS27577.1 - 0.00017 21.8 7.5 0.00046 20.4 7.5 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EPS27577.1 - 0.00046 20.1 9.0 0.0012 18.8 9.0 1.8 1 0 0 1 1 1 1 zinc-RING finger domain Helicase_C PF00271.31 EPS27577.1 - 0.00078 19.8 0.0 0.0028 18.0 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Baculo_IE-1 PF05290.11 EPS27577.1 - 0.0018 18.3 1.1 0.005 16.8 1.1 1.8 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) ResIII PF04851.15 EPS27577.1 - 0.0018 18.3 0.0 0.036 14.1 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-P11 PF03854.14 EPS27577.1 - 0.12 12.1 9.4 0.27 10.9 9.4 1.6 1 0 0 1 1 1 0 P-11 zinc finger zf-C3HC4_4 PF15227.6 EPS27577.1 - 0.12 12.6 8.6 0.26 11.5 8.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EPS27577.1 - 0.83 9.5 7.4 0.28 11.0 4.1 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 EPS27577.1 - 0.91 9.2 8.2 2.5 7.8 8.2 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DZR PF12773.7 EPS27577.1 - 6.2 6.9 6.1 23 5.1 4.2 2.5 2 0 0 2 2 2 0 Double zinc ribbon PNGaseA PF12222.8 EPS27578.1 - 1.2e-166 555.0 0.9 1.5e-166 554.5 0.9 1.2 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF1640 PF07798.11 EPS27579.1 - 1.9e-56 190.9 7.0 2.4e-56 190.6 7.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) TEX33 PF15400.6 EPS27579.1 - 0.011 16.2 1.1 0.24 11.9 0.4 2.3 2 0 0 2 2 2 0 Testis-expressed sequence 33 protein family PMM PF03332.13 EPS27580.1 - 1.9e-103 345.0 0.1 2.2e-103 344.8 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 EPS27580.1 - 0.0089 15.8 0.0 0.05 13.3 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EPS27580.1 - 0.036 13.6 0.0 2.1 7.8 0.0 2.1 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase DnaJ PF00226.31 EPS27581.1 - 2.4e-20 72.4 0.9 3.7e-20 71.8 0.9 1.3 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.13 EPS27581.1 - 0.019 15.2 1.3 0.028 14.7 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Bacteriocin_IIc PF10439.9 EPS27581.1 - 0.024 14.8 5.8 0.04 14.0 5.8 1.3 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_Omp PF13488.6 EPS27581.1 - 0.28 11.2 12.8 0.45 10.6 12.8 1.3 1 0 0 1 1 1 0 Glycine zipper Gly-zipper_YMGG PF13441.6 EPS27581.1 - 1.8 8.4 15.0 4 7.2 3.4 1.8 1 1 1 2 2 2 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.15 EPS27581.1 - 2.7 7.9 16.2 5.5 6.9 16.2 1.5 1 1 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.6 EPS27581.1 - 8 6.3 13.2 13 5.7 12.8 1.5 1 1 0 1 1 1 0 Glycine-zipper domain DnaJ PF00226.31 EPS27583.1 - 5.3e-07 29.7 0.6 1.4e-06 28.3 0.6 1.7 1 0 0 1 1 1 1 DnaJ domain PRA1 PF03208.19 EPS27584.1 - 1.1e-30 106.1 3.4 1.6e-30 105.6 3.4 1.2 1 0 0 1 1 1 1 PRA1 family protein Frag1 PF10277.9 EPS27585.1 - 4.9e-44 150.5 9.5 5.6e-44 150.3 9.5 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF4407 PF14362.6 EPS27585.1 - 1.9 7.8 6.3 1.6 8.0 4.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Y_phosphatase3 PF13350.6 EPS27588.1 - 3e-44 151.7 0.0 4.6e-44 151.1 0.0 1.3 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 EPS27588.1 - 1.9e-07 30.8 0.0 1.4e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EPS27588.1 - 0.004 16.8 0.0 0.0058 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Myotub-related PF06602.14 EPS27588.1 - 0.014 14.3 0.1 0.082 11.8 0.0 1.9 2 0 0 2 2 2 0 Myotubularin-like phosphatase domain DSPc PF00782.20 EPS27588.1 - 0.018 14.8 0.0 0.058 13.2 0.0 1.7 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Glyco_hydro_35 PF01301.19 EPS27589.1 - 5.3e-84 282.5 3.8 7.8e-84 282.0 3.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 EPS27589.1 - 4.2e-59 198.1 0.8 2.5e-32 111.8 0.0 2.8 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.9 EPS27589.1 - 4e-54 183.2 3.0 7e-54 182.4 3.0 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.6 EPS27589.1 - 2.9e-21 74.8 0.1 6.8e-21 73.6 0.1 1.7 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Cellulase PF00150.18 EPS27589.1 - 1.4e-08 34.5 0.9 0.0045 16.5 1.2 2.5 1 1 1 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Eisosome1 PF12757.7 EPS27590.1 - 5.8e-32 110.6 15.5 5.8e-32 110.6 15.5 3.0 2 0 0 2 2 2 1 Eisosome protein 1 DUF4231 PF14015.6 EPS27591.1 - 0.46 11.0 5.5 4.3 7.9 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) MFS_1 PF07690.16 EPS27592.1 - 3.4e-29 101.9 22.5 3.4e-29 101.9 22.5 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS27592.1 - 1.1e-08 34.5 11.1 1.1e-08 34.5 11.1 3.5 2 2 0 3 3 3 1 Sugar (and other) transporter CFEM PF05730.11 EPS27593.1 - 7.6e-12 45.2 13.5 7.6e-12 45.2 13.5 2.0 3 0 0 3 3 3 1 CFEM domain TIL PF01826.17 EPS27593.1 - 0.82 10.0 9.1 1.8 8.9 9.1 1.6 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain SWI-SNF_Ssr4 PF08549.10 EPS27593.1 - 4.5 5.8 5.8 5.1 5.6 5.8 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Ilm1 PF10311.9 EPS27594.1 - 2.8e-50 170.2 2.6 3.3e-50 170.0 2.6 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 Prenyltrans PF00432.21 EPS27595.1 - 1.4e-37 127.1 10.4 5.6e-11 42.0 0.0 6.2 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 EPS27595.1 - 8e-05 21.9 0.0 0.0061 15.7 0.0 2.9 2 1 0 2 2 2 1 Squalene-hopene cyclase C-terminal domain DUF4660 PF15559.6 EPS27595.1 - 0.091 13.1 0.0 0.16 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4660) Nop14 PF04147.12 EPS27595.1 - 2.9 6.0 6.0 3.8 5.6 6.0 1.0 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 EPS27595.1 - 2.9 7.1 6.4 4.2 6.6 6.4 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 EPS27595.1 - 5.8 4.9 9.6 7.1 4.6 9.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 EPS27595.1 - 7.2 4.8 6.6 9.8 4.3 6.6 1.0 1 0 0 1 1 1 0 CDC45-like protein APH PF01636.23 EPS27596.1 - 7.4e-11 42.4 0.0 4.7e-10 39.8 0.0 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EPS27596.1 - 0.0029 16.5 0.0 1.3 7.8 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) EcKinase PF02958.20 EPS27596.1 - 0.0045 16.3 0.0 0.0083 15.5 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase Pkinase PF00069.25 EPS27597.1 - 3.1e-65 220.2 0.0 4.7e-65 219.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS27597.1 - 1.2e-41 142.8 0.0 1.7e-41 142.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EPS27597.1 - 7.2e-08 32.1 0.0 3.6e-07 29.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EPS27597.1 - 2.5e-06 26.7 0.3 2.5e-06 26.7 0.3 2.1 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 EPS27597.1 - 0.037 13.4 0.9 0.093 12.1 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family PRKG1_interact PF15898.5 EPS27597.1 - 0.061 14.2 3.2 0.28 12.1 3.2 2.1 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain Ferlin_C PF16165.5 EPS27597.1 - 0.23 11.4 0.2 0.48 10.4 0.2 1.5 1 0 0 1 1 1 0 Ferlin C-terminus APH PF01636.23 EPS27597.1 - 3.6 7.4 7.5 0.99 9.3 0.1 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.22 EPS27597.1 - 6.2 6.4 5.8 0.76 9.3 0.1 2.2 3 0 0 3 3 3 0 RIO1 family MFS_1 PF07690.16 EPS27598.1 - 9.8e-17 60.9 26.4 9.8e-17 60.9 26.4 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS27598.1 - 2.3e-06 26.8 3.6 2.3e-06 26.8 3.6 3.0 2 1 0 3 3 3 1 Sugar (and other) transporter DUF4293 PF14126.6 EPS27598.1 - 0.049 13.9 0.6 0.049 13.9 0.6 2.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4293) DUF2811 PF10929.8 EPS27598.1 - 0.066 13.5 0.1 0.15 12.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) LapA_dom PF06305.11 EPS27598.1 - 0.16 11.8 0.1 0.16 11.8 0.1 3.2 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain DUF2523 PF10734.9 EPS27598.1 - 0.26 11.9 3.3 2.2 8.9 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2523) HlyIII PF03006.20 EPS27598.1 - 1 9.0 10.6 0.074 12.8 0.4 2.9 2 2 1 3 3 3 0 Haemolysin-III related E1-E2_ATPase PF00122.20 EPS27599.1 - 1.5e-51 174.5 5.9 1.1e-50 171.7 0.9 3.1 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EPS27599.1 - 1.6e-47 161.6 8.9 2.5e-47 161.0 6.3 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EPS27599.1 - 1.1e-22 81.4 1.7 5.4e-22 79.1 0.2 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EPS27599.1 - 4e-17 61.7 0.1 1.9e-16 59.5 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EPS27599.1 - 1.1e-16 60.7 0.0 2e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EPS27599.1 - 3.6e-08 33.5 1.3 4.5e-06 26.6 1.0 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EPS27599.1 - 2.1e-07 31.5 0.0 1e-06 29.3 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase 14-3-3 PF00244.20 EPS27601.1 - 1.6e-107 358.1 1.9 2e-107 357.8 1.9 1.1 1 0 0 1 1 1 1 14-3-3 protein Orbi_VP5 PF00901.17 EPS27601.1 - 0.011 14.1 1.4 0.018 13.5 1.4 1.3 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Ribosomal_60s PF00428.19 EPS27601.1 - 4.7 7.9 16.6 24 5.6 13.2 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein eIF3_subunit PF08597.10 EPS27602.1 - 9.9e-69 231.9 28.9 1.1e-68 231.8 28.9 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit CDC27 PF09507.10 EPS27602.1 - 1.2 8.4 27.1 0.11 11.9 19.3 2.1 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 LRIF1 PF15741.5 EPS27602.1 - 3.7 6.0 12.1 0.42 9.1 5.9 1.9 2 0 0 2 2 2 0 Ligand-dependent nuclear receptor-interacting factor 1 Enolase_C PF00113.22 EPS27603.1 - 8e-152 504.6 0.1 1.1e-151 504.2 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EPS27603.1 - 6.5e-58 194.6 0.2 1.3e-57 193.6 0.2 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 EPS27603.1 - 1.7e-05 24.5 0.0 3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like AAA PF00004.29 EPS27604.1 - 6.7e-43 146.3 0.0 1.1e-42 145.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EPS27604.1 - 1.2e-11 44.3 0.1 9.5e-11 41.5 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EPS27604.1 - 4.4e-10 39.2 0.1 8e-10 38.4 0.1 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EPS27604.1 - 6.1e-07 30.0 0.0 0.00028 21.3 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 EPS27604.1 - 2.1e-06 28.0 0.0 6.6e-06 26.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EPS27604.1 - 2.5e-06 27.5 0.0 6.3e-05 23.0 0.0 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EPS27604.1 - 3.3e-06 27.0 0.0 7e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 EPS27604.1 - 0.00039 19.7 0.0 0.00076 18.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_7 PF12775.7 EPS27604.1 - 0.00057 19.5 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 EPS27604.1 - 0.00058 20.1 0.1 0.02 15.2 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 EPS27604.1 - 0.0013 19.3 0.0 0.0042 17.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 EPS27604.1 - 0.0031 16.8 0.0 0.006 15.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain GAS PF13851.6 EPS27604.1 - 0.0036 16.7 0.5 0.0073 15.7 0.5 1.5 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Prot_ATP_OB_N PF17758.1 EPS27604.1 - 0.0042 16.7 0.0 0.012 15.2 0.0 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain TsaE PF02367.17 EPS27604.1 - 0.0053 16.8 0.0 0.014 15.3 0.0 1.7 2 0 0 2 2 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 EPS27604.1 - 0.0055 16.4 0.0 0.017 14.8 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 EPS27604.1 - 0.0061 16.0 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EPS27604.1 - 0.0078 16.0 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 EPS27604.1 - 0.0092 15.8 0.0 0.023 14.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EPS27604.1 - 0.013 15.9 0.0 0.024 15.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 EPS27604.1 - 0.015 15.3 0.0 0.038 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EPS27604.1 - 0.019 15.2 0.0 0.043 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EPS27604.1 - 0.036 13.4 0.0 0.14 11.5 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_24 PF13479.6 EPS27604.1 - 0.036 13.8 0.1 0.096 12.4 0.0 1.8 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.12 EPS27604.1 - 0.051 12.8 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin PhoH PF02562.16 EPS27604.1 - 0.054 12.9 0.0 0.094 12.2 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.6 EPS27604.1 - 0.057 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 EPS27604.1 - 0.058 12.5 0.0 0.09 11.8 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.6 EPS27604.1 - 0.085 12.6 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EPS27604.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EPS27604.1 - 0.13 12.2 0.1 0.32 10.9 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_11 PF13086.6 EPS27604.1 - 0.15 11.8 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain SHNi-TPR PF10516.9 EPS27604.1 - 0.17 11.3 0.4 2.1 7.9 0.2 2.6 2 0 0 2 2 2 0 SHNi-TPR Glyco_hydro_47 PF01532.20 EPS27605.1 - 1.7e-168 561.3 0.0 2.1e-168 561.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 M20_dimer PF07687.14 EPS27606.1 - 1.2e-18 67.0 0.1 2.2e-18 66.2 0.1 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.28 EPS27606.1 - 2.3e-17 63.4 3.2 1.5e-16 60.7 3.2 2.1 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 EPS27606.1 - 0.0027 16.8 0.0 0.27 10.2 0.0 2.9 3 0 0 3 3 3 1 M42 glutamyl aminopeptidase Peptidase_M28 PF04389.17 EPS27606.1 - 0.025 14.3 0.0 0.066 12.9 0.0 1.7 1 0 0 1 1 1 0 Peptidase family M28 PNK3P PF08645.11 EPS27609.1 - 2.7e-56 189.7 0.1 4.3e-56 189.1 0.1 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 EPS27609.1 - 1.5e-24 86.8 0.0 5.9e-14 52.4 0.1 2.3 1 1 1 2 2 2 2 AAA domain KTI12 PF08433.10 EPS27609.1 - 0.00046 19.7 2.5 0.22 11.0 0.0 2.8 2 1 0 3 3 3 2 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 EPS27609.1 - 0.049 12.9 0.1 2.5 7.3 0.0 2.5 3 0 0 3 3 3 0 Zeta toxin Hydrolase_6 PF13344.6 EPS27609.1 - 0.06 13.5 0.1 0.94 9.6 0.0 2.6 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Med18 PF09637.10 EPS27610.1 - 3e-62 210.7 0.0 3.4e-62 210.5 0.0 1.0 1 0 0 1 1 1 1 Med18 protein CSD PF00313.22 EPS27610.1 - 0.19 11.6 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain S36_mt PF10937.8 EPS27611.1 - 9.6e-39 133.5 0.2 1.1e-38 133.3 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S36, mitochondrial RGS PF00615.19 EPS27612.1 - 4.4e-06 27.0 0.0 6.4e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Rhodanese PF00581.20 EPS27613.1 - 3.4e-08 34.0 0.0 4.8e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Isochorismatase PF00857.20 EPS27615.1 - 5.1e-16 59.4 0.2 5.9e-15 55.9 0.2 2.1 1 1 0 1 1 1 1 Isochorismatase family ERGIC_N PF13850.6 EPS27615.1 - 0.074 13.4 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Fungal_trans_2 PF11951.8 EPS27616.1 - 2.8e-08 33.0 0.2 3.2e-05 22.9 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Pkinase PF00069.25 EPS27617.1 - 9.6e-28 97.3 0.0 1.2e-27 97.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS27617.1 - 1.9e-14 53.6 0.0 2.4e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EPS27617.1 - 4e-07 29.1 0.0 6.5e-07 28.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase DLIC PF05783.11 EPS27617.1 - 0.13 11.1 5.1 0.17 10.6 5.1 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Rtt106 PF08512.12 EPS27619.1 - 3e-31 107.7 0.1 1.1e-30 105.9 0.0 1.9 2 0 0 2 2 2 1 Histone chaperone Rttp106-like PH_18 PF18469.1 EPS27619.1 - 0.0025 17.8 0.0 0.0062 16.5 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain Cwf_Cwc_15 PF04889.12 EPS27619.1 - 1.7 8.3 19.8 2.9 7.5 19.8 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NPR3 PF03666.13 EPS27619.1 - 3.6 6.3 4.4 5.5 5.7 4.4 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Vfa1 PF08432.10 EPS27619.1 - 5.7 7.2 7.3 11 6.4 7.3 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Tom37_C PF11801.8 EPS27620.1 - 0.028 14.4 4.7 0.4 10.6 0.1 2.4 2 0 0 2 2 2 0 Tom37 C-terminal domain KOW PF00467.29 EPS27620.1 - 0.057 13.4 0.0 0.099 12.6 0.0 1.4 1 0 0 1 1 1 0 KOW motif Fungal_trans PF04082.18 EPS27621.1 - 5e-10 38.8 0.1 8.1e-10 38.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Phage_holin_3_7 PF05449.11 EPS27621.1 - 0.067 13.2 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Putative 3TM holin, Phage_holin_3 bZIP_1 PF00170.21 EPS27622.1 - 8.1e-06 25.8 6.8 1.2e-05 25.2 6.8 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EPS27622.1 - 0.00096 19.2 11.0 0.0014 18.6 11.0 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 EPS27622.1 - 0.0049 17.4 2.4 0.0049 17.4 2.4 2.0 3 0 0 3 3 3 1 bZIP Maf transcription factor RecG_N PF17190.4 EPS27622.1 - 0.12 13.2 1.7 0.19 12.4 1.7 1.3 1 0 0 1 1 1 0 RecG N-terminal helical domain DUF4337 PF14235.6 EPS27622.1 - 0.14 12.3 0.9 0.21 11.7 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) RFXA_RFXANK_bdg PF15289.6 EPS27622.1 - 0.37 11.1 4.1 0.24 11.7 1.0 2.0 1 1 1 2 2 2 0 Regulatory factor X-associated C-terminal binding domain DUF1635 PF07795.11 EPS27622.1 - 1.4 8.7 5.9 0.36 10.6 2.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Homoserine_dh PF00742.19 EPS27623.1 - 1.7e-39 135.6 0.0 2.1e-39 135.2 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 EPS27623.1 - 2.6e-14 53.9 0.0 6.1e-14 52.7 0.0 1.7 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Ras PF00071.22 EPS27625.1 - 1.3e-55 187.4 0.0 1.6e-55 187.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EPS27625.1 - 7.5e-22 77.8 0.0 1.2e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPS27625.1 - 4.9e-07 29.4 0.0 7.8e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EPS27625.1 - 0.0017 17.8 0.0 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit NB-ARC PF00931.22 EPS27625.1 - 0.035 13.3 0.1 0.32 10.1 0.0 2.0 1 1 1 2 2 2 0 NB-ARC domain baeRF_family3 PF18845.1 EPS27625.1 - 0.11 12.7 0.1 0.52 10.6 0.0 1.8 1 1 1 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 3 Gtr1_RagA PF04670.12 EPS27625.1 - 0.18 11.1 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF1712 PF08217.11 EPS27626.1 - 5.6e-15 54.8 0.0 7.4e-13 47.9 0.0 2.8 2 1 0 2 2 2 2 Fungal domain of unknown function (DUF1712) Formyl_trans_N PF00551.19 EPS27627.1 - 5.2e-20 71.9 0.1 8.6e-20 71.2 0.1 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 EPS27627.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 Formyl transferase, C-terminal domain Alg14 PF08660.11 EPS27628.1 - 3.1e-53 180.3 0.1 5.3e-53 179.5 0.1 1.3 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Glyco_trans_4_4 PF13579.6 EPS27628.1 - 0.0022 18.4 0.7 0.0035 17.8 0.7 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain AHJR-like PF18743.1 EPS27628.1 - 0.071 12.7 0.0 0.24 11.0 0.0 1.7 2 0 0 2 2 2 0 REase_AHJR-like Ima1_N PF09779.9 EPS27629.1 - 9.6e-32 110.7 3.7 1.8e-31 109.7 3.7 1.5 1 0 0 1 1 1 1 Ima1 N-terminal domain DUF2767 PF10965.8 EPS27629.1 - 0.081 12.9 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2767) Zn_Tnp_IS1595 PF12760.7 EPS27629.1 - 0.4 10.7 5.4 0.14 12.2 1.9 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain RNHCP PF12647.7 EPS27629.1 - 1.9 8.5 5.3 0.62 10.1 1.1 2.1 1 1 0 2 2 2 0 RNHCP domain DZR PF12773.7 EPS27629.1 - 3.4 7.8 8.7 1.4 9.0 0.4 2.9 2 1 0 2 2 2 0 Double zinc ribbon Sugar_tr PF00083.24 EPS27630.1 - 2.1e-120 402.7 24.5 2.4e-120 402.5 24.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS27630.1 - 1.4e-17 63.7 50.8 7.4e-17 61.3 21.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily NmrA PF05368.13 EPS27631.1 - 7.8e-10 38.7 0.0 1.2e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPS27631.1 - 7.4e-06 26.0 0.0 1.6e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding UBA_4 PF14555.6 EPS27631.1 - 0.24 11.2 1.3 7.2 6.5 0.0 3.4 4 0 0 4 4 4 0 UBA-like domain BPL_LplA_LipB PF03099.19 EPS27633.1 - 6.7e-07 29.3 0.0 1.5e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Chorismate_synt PF01264.21 EPS27634.1 - 4.9e-140 465.9 0.0 5.6e-140 465.7 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Kelch_5 PF13854.6 EPS27635.1 - 0.00045 20.1 0.0 0.044 13.8 0.0 2.8 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.6 EPS27635.1 - 0.00079 19.4 1.0 1.9 8.5 0.1 4.3 4 0 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.15 EPS27635.1 - 0.025 14.5 0.1 0.77 9.8 0.0 3.1 2 0 0 2 2 2 0 Kelch motif Pkinase PF00069.25 EPS27637.1 - 2.9e-52 177.6 0.6 2.5e-34 118.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EPS27637.1 - 1.7e-27 96.3 0.0 3e-26 92.3 0.0 2.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EPS27637.1 - 0.00086 19.3 0.8 0.01 15.8 0.8 2.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EPS27637.1 - 0.0011 17.8 0.0 0.0011 17.8 0.0 2.3 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 EPS27637.1 - 0.0014 18.0 0.0 0.0036 16.6 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Glyco_hydro_53 PF07745.13 EPS27639.1 - 2.2e-103 345.9 0.2 2.7e-103 345.6 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 zf-C2H2 PF00096.26 EPS27640.1 - 1e-12 47.7 11.6 3.9e-06 27.0 2.4 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EPS27640.1 - 4.8e-12 45.7 9.2 2e-07 31.1 0.2 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EPS27640.1 - 3e-08 33.8 11.9 0.00044 20.9 1.5 3.9 4 0 0 4 4 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EPS27640.1 - 3.5e-08 33.2 5.4 0.00035 20.5 0.3 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EPS27640.1 - 4.3e-06 26.8 0.7 0.095 13.0 0.1 3.6 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EPS27640.1 - 9e-05 22.7 2.2 0.014 15.7 0.2 3.4 4 0 0 4 4 3 1 Zinc-finger of C2H2 type zf-C2H2_11 PF16622.5 EPS27640.1 - 0.0063 16.2 4.8 0.44 10.3 0.7 3.4 3 0 0 3 3 3 1 zinc-finger C2H2-type zf-Di19 PF05605.12 EPS27640.1 - 0.1 12.9 1.4 0.19 12.0 1.4 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HE PF16278.5 EPS27640.1 - 0.31 11.5 1.7 11 6.6 0.2 2.5 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger LIM PF00412.22 EPS27640.1 - 0.55 10.5 2.9 19 5.6 0.1 2.3 1 1 1 2 2 2 0 LIM domain SUIM_assoc PF16619.5 EPS27640.1 - 3.4 7.8 8.8 0.11 12.5 1.1 2.5 2 1 1 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 C5HCH PF17982.1 EPS27640.1 - 5.4 7.3 5.9 27 5.0 0.4 2.6 1 1 1 2 2 2 0 NSD Cys-His rich domain ALG11_N PF15924.5 EPS27641.1 - 2.1e-83 279.5 0.0 2.8e-83 279.1 0.0 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 EPS27641.1 - 1.9e-18 66.6 0.0 3.5e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EPS27641.1 - 4.2e-10 40.2 0.0 2.2e-09 37.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 AAA_5 PF07728.14 EPS27641.1 - 0.0001 22.3 0.0 0.00026 21.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Glyco_transf_4 PF13439.6 EPS27641.1 - 0.0011 19.0 0.0 0.0037 17.3 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase Family 4 60KD_IMP PF02096.20 EPS27642.1 - 7.3e-09 35.7 0.1 1.2e-08 35.1 0.1 1.5 1 1 0 1 1 1 1 60Kd inner membrane protein PP2C PF00481.21 EPS27643.1 - 1.4e-41 142.8 0.0 2.9e-41 141.8 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EPS27643.1 - 6e-07 29.3 0.1 2.4e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.12 EPS27643.1 - 9e-05 22.5 0.0 0.71 9.8 0.0 2.8 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) Tcf25 PF04910.14 EPS27644.1 - 5.6e-75 252.6 0.1 7.4e-75 252.2 0.1 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 PGA2 PF07543.12 EPS27644.1 - 0.93 9.5 11.7 1.7 8.6 11.7 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 DUF3807 PF12720.7 EPS27644.1 - 9.7 6.4 13.2 17 5.6 13.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) PQ-loop PF04193.14 EPS27645.1 - 1.5e-39 133.5 5.6 3.9e-20 71.4 0.2 2.6 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 EPS27645.1 - 0.017 15.9 0.6 0.94 10.3 0.0 2.6 3 0 0 3 3 3 0 ER lumen protein retaining receptor Ribosomal_60s PF00428.19 EPS27646.1 - 5.3e-28 97.5 10.6 6.3e-28 97.2 10.6 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2408 PF10303.9 EPS27647.1 - 6.6e-46 156.2 5.9 3.2e-28 99.0 2.7 4.9 3 2 1 4 4 4 4 Protein of unknown function (DUF2408) Spc7 PF08317.11 EPS27647.1 - 0.0026 16.7 1.4 0.0047 15.9 0.7 1.6 1 1 0 1 1 1 1 Spc7 kinetochore protein FRB_dom PF08771.11 EPS27647.1 - 0.13 12.7 0.1 27 5.3 0.0 2.7 2 1 0 2 2 2 0 FKBP12-rapamycin binding domain Prefoldin_2 PF01920.20 EPS27647.1 - 0.22 11.5 2.7 9.6 6.2 0.3 3.1 1 1 2 3 3 3 0 Prefoldin subunit Snapin_Pallidin PF14712.6 EPS27647.1 - 0.72 10.3 3.3 4.7 7.7 0.3 3.5 4 0 0 4 4 4 0 Snapin/Pallidin Dynamitin PF04912.14 EPS27647.1 - 0.83 8.9 5.8 1.5 8.0 0.1 2.9 2 1 1 3 3 3 0 Dynamitin XhlA PF10779.9 EPS27647.1 - 0.85 9.9 7.7 4.7 7.5 0.8 4.1 3 1 1 4 4 4 0 Haemolysin XhlA Aconitase PF00330.20 EPS27648.1 - 7.2e-144 480.2 0.0 8.9e-144 479.9 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EPS27648.1 - 8.8e-40 136.1 0.0 1.4e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain PALP PF00291.25 EPS27649.1 - 3.5e-52 177.7 0.0 4.6e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.26 EPS27649.1 - 0.012 15.6 0.1 0.4 10.7 0.0 2.6 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Ank_2 PF12796.7 EPS27650.1 - 7.8e-08 32.8 0.2 2.7e-06 27.9 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EPS27650.1 - 8e-08 32.0 0.1 0.028 14.9 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EPS27650.1 - 8e-08 32.4 0.7 0.016 15.6 0.0 3.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EPS27650.1 - 2.4e-05 24.6 0.0 0.31 11.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EPS27650.1 - 0.00054 20.5 0.4 0.059 14.0 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) TFIIS_C PF01096.18 EPS27651.1 - 4.5e-20 71.2 2.2 4.5e-20 71.2 2.2 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EPS27651.1 - 1.1e-07 31.5 4.9 1.5e-06 27.9 1.8 3.2 3 1 0 3 3 3 1 RNA polymerases M/15 Kd subunit IBR PF01485.21 EPS27651.1 - 0.001 19.3 5.3 0.23 11.7 0.5 2.4 2 1 0 2 2 2 2 IBR domain, a half RING-finger domain Zn_Tnp_IS1595 PF12760.7 EPS27651.1 - 0.0022 17.9 5.8 0.042 13.8 0.5 2.4 2 1 0 2 2 2 2 Transposase zinc-ribbon domain zf-DNL PF05180.12 EPS27651.1 - 0.0066 16.4 1.1 0.31 11.0 0.2 3.0 2 1 0 2 2 2 1 DNL zinc finger Zn_ribbon_recom PF13408.6 EPS27651.1 - 0.0085 16.6 0.6 0.38 11.3 0.1 2.5 2 0 0 2 2 2 1 Recombinase zinc beta ribbon domain ADD_ATRX PF17981.1 EPS27651.1 - 0.03 14.2 0.4 4.2 7.3 0.1 2.4 2 0 0 2 2 2 0 Cysteine Rich ADD domain zinc_ribbon_12 PF11331.8 EPS27651.1 - 0.11 12.3 2.7 0.48 10.3 0.6 2.3 2 0 0 2 2 2 0 Probable zinc-ribbon domain zf_Rg PF17915.1 EPS27651.1 - 0.43 10.0 3.2 2.4 7.6 0.0 2.8 3 0 0 3 3 3 0 Reverse gyrase zinc finger TF_Zn_Ribbon PF08271.12 EPS27651.1 - 0.77 9.3 8.9 2.6 7.6 1.1 3.0 3 1 0 3 3 3 0 TFIIB zinc-binding zf-TFIIB PF13453.6 EPS27651.1 - 1.3 8.4 7.0 0.46 9.8 0.3 3.1 3 1 0 3 3 3 0 Transcription factor zinc-finger Zn_Tnp_IS1 PF03811.13 EPS27651.1 - 1.7 8.5 9.0 0.23 11.2 1.8 2.9 3 1 0 3 3 3 0 InsA N-terminal domain zf-H2C2_2 PF13465.6 EPS27651.1 - 3.7 8.1 7.8 10 6.7 0.2 3.6 4 0 0 4 4 4 0 Zinc-finger double domain zf-RING_7 PF02591.15 EPS27651.1 - 5.5 7.3 7.4 8.2 6.7 0.6 3.1 4 0 0 4 4 3 0 C4-type zinc ribbon domain GTP_EFTU PF00009.27 EPS27652.1 - 4.8e-54 182.8 0.0 7.2e-54 182.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EPS27652.1 - 1.4e-41 141.3 0.0 3.2e-41 140.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EPS27652.1 - 3.2e-13 49.9 1.0 3.2e-13 49.9 1.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EPS27652.1 - 0.00018 21.6 0.1 0.0042 17.1 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Semialdhyde_dhC PF02774.18 EPS27652.1 - 0.012 15.7 0.1 0.14 12.2 0.1 2.2 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain GTP_EFTU_D4 PF14578.6 EPS27652.1 - 0.051 13.5 0.8 0.15 12.0 0.8 1.8 1 0 0 1 1 1 0 Elongation factor Tu domain 4 FlpD PF02662.16 EPS27652.1 - 0.14 12.2 0.0 0.4 10.7 0.0 1.7 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit MAGE PF01454.19 EPS27653.1 - 4.8e-65 219.2 0.2 9.2e-65 218.3 0.0 1.5 2 0 0 2 2 2 1 MAGE family Ribosomal_L27e PF01777.18 EPS27655.1 - 4.7e-36 123.0 1.5 6.5e-36 122.6 1.5 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 EPS27655.1 - 0.00036 20.4 0.3 0.00099 19.0 0.3 1.8 1 0 0 1 1 1 1 KOW motif ATG16 PF08614.11 EPS27656.1 - 0.0014 18.9 3.4 0.0014 18.9 3.4 10.7 8 3 5 13 13 13 2 Autophagy protein 16 (ATG16) MCC-bdg_PDZ PF10506.9 EPS27656.1 - 0.46 10.5 4.2 2 8.5 1.1 3.9 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF5338 PF17273.2 EPS27656.1 - 0.69 10.0 10.7 15 5.8 0.0 6.6 7 0 0 7 7 7 0 Family of unknown function (DUF5338) TRAM_LAG1_CLN8 PF03798.16 EPS27657.1 - 5.3e-55 186.2 16.8 8.4e-55 185.6 16.8 1.3 1 0 0 1 1 1 1 TLC domain SWIB PF02201.18 EPS27658.1 - 7.5e-24 83.4 0.0 1.6e-23 82.4 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain RPN6_N PF18055.1 EPS27659.1 - 7.6e-44 148.8 0.3 3e-43 146.9 0.1 2.1 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 EPS27659.1 - 3.8e-21 75.6 2.0 7.8e-21 74.6 0.2 2.4 2 1 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 EPS27659.1 - 3.2e-11 42.8 0.3 8.4e-11 41.4 0.3 1.8 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain DDRGK PF09756.9 EPS27659.1 - 8.4e-05 22.2 0.2 0.00015 21.4 0.2 1.3 1 0 0 1 1 1 1 DDRGK domain TPR_12 PF13424.6 EPS27659.1 - 0.0006 20.0 16.7 0.26 11.6 0.2 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat HTH_Crp_2 PF13545.6 EPS27659.1 - 0.0012 18.7 0.1 0.41 10.7 0.0 2.9 2 1 0 2 2 2 1 Crp-like helix-turn-helix domain DprA_WH PF17782.1 EPS27659.1 - 0.02 15.0 0.1 0.41 10.8 0.0 2.6 2 0 0 2 2 2 0 DprA winged helix domain DUF410 PF04190.13 EPS27659.1 - 0.026 14.3 0.1 0.026 14.3 0.1 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF410) Prefoldin_2 PF01920.20 EPS27659.1 - 0.047 13.6 2.9 0.064 13.2 0.7 2.3 2 0 0 2 2 2 0 Prefoldin subunit T3SchapCesA PF11439.8 EPS27659.1 - 0.13 12.4 0.5 24 5.2 0.0 3.8 3 2 0 3 3 3 0 Type III secretion system filament chaperone CesA TPR_1 PF00515.28 EPS27659.1 - 0.18 11.7 6.0 1.8 8.5 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_MalT PF17874.1 EPS27659.1 - 0.31 10.4 10.8 0.054 12.9 5.7 2.1 2 1 0 2 2 2 0 MalT-like TPR region DUF3496 PF12001.8 EPS27659.1 - 0.32 11.4 1.8 1.9 8.9 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3496) TPR_8 PF13181.6 EPS27659.1 - 0.33 11.3 4.5 1.3e+02 3.2 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 EPS27659.1 - 0.73 10.8 11.6 18 6.5 0.0 5.9 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.17 EPS27659.1 - 1.8 8.9 9.1 39 4.7 0.6 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat Sof1 PF04158.14 EPS27660.1 - 1e-30 105.8 11.3 2.3e-30 104.7 11.3 1.6 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 EPS27660.1 - 3e-27 94.3 3.9 2.6e-05 24.9 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS27660.1 - 3.6e-07 30.4 0.2 0.18 12.1 0.0 4.2 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EPS27660.1 - 1.9e-05 23.8 0.0 0.0065 15.5 0.0 3.0 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EPS27660.1 - 0.025 14.4 0.2 0.075 12.9 0.0 1.8 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A adh_short PF00106.25 EPS27661.1 - 5.9e-38 130.3 0.1 8.6e-38 129.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS27661.1 - 3.4e-26 92.3 0.0 5.9e-26 91.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPS27661.1 - 1.7e-11 44.4 0.1 2.7e-11 43.7 0.1 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EPS27661.1 - 0.0002 20.8 0.0 0.00028 20.3 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) 3Beta_HSD PF01073.19 EPS27661.1 - 0.0023 17.0 0.1 0.0034 16.4 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EPS27661.1 - 0.06 12.8 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DAP10 PF07213.11 EPS27661.1 - 0.13 12.2 0.2 11 6.1 0.0 2.6 2 0 0 2 2 2 0 DAP10 membrane protein PHD PF00628.29 EPS27662.1 - 1.6e-10 40.7 8.5 2.7e-10 40.0 8.5 1.4 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 EPS27662.1 - 0.025 14.5 3.1 0.025 14.5 3.1 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 EPS27662.1 - 0.12 12.3 4.8 0.27 11.2 4.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-RRPl_C4 PF17026.5 EPS27662.1 - 0.21 11.7 1.2 0.41 10.8 1.2 1.5 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type PHD_2 PF13831.6 EPS27662.1 - 0.22 11.1 13.1 0.06 12.9 8.3 2.4 2 1 0 2 2 2 0 PHD-finger zf-PHD-like PF15446.6 EPS27662.1 - 0.26 10.9 8.5 0.048 13.3 3.8 2.2 2 1 0 2 2 2 0 PHD/FYVE-zinc-finger like domain CxC3 PF18804.1 EPS27662.1 - 1.9 8.4 4.9 1.2 9.1 0.7 2.6 3 0 0 3 3 3 0 CxC3 like cysteine cluster associated with KDZ transposases Herpes_UL52 PF03121.15 EPS27662.1 - 9.9 6.2 8.5 0.6 10.1 3.1 1.7 2 0 0 2 2 2 0 Herpesviridae UL52/UL70 DNA primase CoA_transf_3 PF02515.17 EPS27663.1 - 1.4e-130 435.7 0.0 1.6e-130 435.5 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III Lum_binding PF00677.17 EPS27664.1 - 6.4e-44 147.9 2.1 5.7e-23 80.7 0.2 2.2 2 0 0 2 2 2 2 Lumazine binding domain DUF3127 PF11325.8 EPS27664.1 - 0.047 13.9 0.1 0.13 12.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3127) MFS_1 PF07690.16 EPS27665.1 - 9.3e-32 110.3 46.5 2.4e-31 108.9 46.5 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EPS27665.1 - 1.6e-10 40.0 7.4 1.6e-10 40.0 7.4 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) AMP-binding PF00501.28 EPS27666.1 - 1.9e-296 982.1 0.0 3.4e-77 259.8 0.0 4.2 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.20 EPS27666.1 - 4.6e-137 457.4 3.5 6.3e-38 130.6 0.0 6.4 4 3 0 4 4 4 4 Condensation domain PP-binding PF00550.25 EPS27666.1 - 5.9e-44 148.3 7.6 1.3e-11 44.7 0.1 5.9 5 0 0 5 5 5 4 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EPS27666.1 - 5.7e-14 52.8 0.0 0.011 16.7 0.0 4.8 4 0 0 4 4 4 4 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.16 EPS27666.1 - 2.4e-05 24.3 0.0 0.23 11.2 0.0 2.6 2 0 0 2 2 2 2 Wax ester synthase-like Acyl-CoA acyltransferase domain AATase PF07247.12 EPS27667.1 - 2.7e-15 55.9 0.0 4.5e-14 51.9 0.0 2.6 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.20 EPS27667.1 - 1.8e-05 23.6 0.0 0.047 12.4 0.0 2.2 2 0 0 2 2 2 2 Condensation domain WES_acyltransf PF03007.16 EPS27667.1 - 0.15 11.8 0.1 0.27 11.0 0.1 1.5 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain 2C_adapt PF08793.10 EPS27667.1 - 0.23 11.7 0.7 0.47 10.7 0.7 1.5 1 0 0 1 1 1 0 2-cysteine adaptor domain Peptidase_M20 PF01546.28 EPS27668.1 - 5.1e-29 101.5 0.3 7.7e-29 100.9 0.3 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 EPS27668.1 - 2e-05 24.4 0.0 0.00017 21.3 0.0 2.4 2 2 0 2 2 2 1 Peptidase family M28 M20_dimer PF07687.14 EPS27668.1 - 5.6e-05 23.0 0.0 0.00014 21.7 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_S9 PF00326.21 EPS27669.1 - 2.8e-39 134.8 2.0 3.8e-38 131.1 2.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 EPS27669.1 - 3.9e-10 39.4 0.1 0.015 15.3 0.0 3.7 3 0 0 3 3 3 3 WD40-like Beta Propeller Repeat Abhydrolase_2 PF02230.16 EPS27669.1 - 2.2e-08 34.2 0.0 0.0007 19.5 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 EPS27669.1 - 3.8e-08 33.2 2.0 0.00043 20.0 0.7 2.3 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 EPS27669.1 - 1.5e-07 31.2 0.0 0.00039 20.0 0.0 2.4 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 EPS27669.1 - 2e-07 31.8 5.1 5.7e-07 30.4 5.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 EPS27669.1 - 2.1e-07 31.0 0.0 4.1e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 EPS27669.1 - 2e-06 27.7 1.7 0.0012 18.5 1.7 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EPS27669.1 - 6.2e-06 25.7 0.3 0.098 11.9 0.0 2.5 2 0 0 2 2 2 2 Serine aminopeptidase, S33 LIP PF03583.14 EPS27669.1 - 1.1e-05 24.9 0.3 0.0052 16.1 0.1 2.1 2 0 0 2 2 2 2 Secretory lipase FSH1 PF03959.13 EPS27669.1 - 0.00041 20.1 0.0 0.00087 19.0 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DPPIV_N PF00930.21 EPS27669.1 - 0.0012 17.7 0.1 1.1 7.9 0.0 2.9 1 1 1 2 2 2 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region BAAT_C PF08840.11 EPS27669.1 - 0.0015 18.5 0.0 0.0032 17.4 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.12 EPS27669.1 - 0.0036 16.0 0.0 0.0063 15.2 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) eIF2A PF08662.11 EPS27669.1 - 0.009 15.9 0.0 3.7 7.4 0.0 2.5 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Esterase PF00756.20 EPS27669.1 - 0.022 14.4 0.1 0.04 13.6 0.1 1.4 1 0 0 1 1 1 0 Putative esterase Abhydrolase_4 PF08386.10 EPS27669.1 - 0.029 14.5 0.0 0.066 13.3 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein DUF2920 PF11144.8 EPS27669.1 - 0.16 11.1 0.0 3.6 6.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) Ank_2 PF12796.7 EPS27670.1 - 2.3e-28 98.6 1.8 1.1e-15 58.0 0.2 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EPS27670.1 - 8.8e-16 57.8 1.7 4.7e-12 45.9 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EPS27670.1 - 1.5e-13 50.5 2.2 0.00014 22.2 0.1 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 EPS27670.1 - 2.5e-13 48.9 0.3 0.0002 21.5 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 EPS27670.1 - 4.7e-12 46.2 0.5 1.8e-06 28.4 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Mto2_bdg PF12808.7 EPS27670.1 - 0.062 13.6 0.9 0.14 12.5 0.9 1.6 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region bZIP_2 PF07716.15 EPS27670.1 - 0.08 13.0 0.8 0.12 12.5 0.8 1.3 1 0 0 1 1 1 0 Basic region leucine zipper Mei4 PF13971.6 EPS27670.1 - 0.12 11.8 0.2 0.15 11.5 0.2 1.1 1 0 0 1 1 1 0 Meiosis-specific protein Mei4 Shugoshin_N PF07558.11 EPS27670.1 - 0.22 11.4 1.4 0.41 10.6 1.4 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region Brix PF04427.18 EPS27672.1 - 1.2e-51 175.6 0.4 1.7e-51 175.1 0.4 1.2 1 0 0 1 1 1 1 Brix domain PBP_sp32 PF07222.12 EPS27672.1 - 1.6 8.1 7.4 2.8 7.3 7.4 1.5 1 0 0 1 1 1 0 Proacrosin binding protein sp32 PPL5 PF18168.1 EPS27672.1 - 8.1 5.6 14.4 5.6 6.2 8.9 2.4 2 1 0 2 2 2 0 Prim-pol family 5 DEAD PF00270.29 EPS27673.1 - 4.7e-47 160.0 0.0 7.1e-47 159.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPS27673.1 - 2.6e-29 101.8 0.0 8.6e-29 100.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPS27673.1 - 6e-07 29.6 0.0 2.1e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1087 PF06465.13 EPS27673.1 - 0.27 11.3 1.6 0.7 10.0 1.6 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1087) AAA PF00004.29 EPS27674.1 - 1.3e-40 138.9 0.0 2.6e-40 137.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EPS27674.1 - 1.5e-17 63.2 0.3 3.2e-17 62.2 0.3 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EPS27674.1 - 1.4e-09 37.6 0.0 3.2e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EPS27674.1 - 5.6e-05 23.2 0.1 0.00028 20.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EPS27674.1 - 6.5e-05 22.7 0.0 0.00016 21.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EPS27674.1 - 0.00017 22.0 1.3 0.022 15.1 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 EPS27674.1 - 0.0027 17.8 1.9 0.012 15.7 0.0 2.9 3 1 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EPS27674.1 - 0.0037 17.5 1.6 0.2 11.9 0.0 2.9 2 1 1 3 3 3 1 AAA domain DUF815 PF05673.13 EPS27674.1 - 0.0038 16.4 0.0 0.011 14.9 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF815) PhoH PF02562.16 EPS27674.1 - 0.0054 16.2 0.2 0.079 12.4 0.1 2.3 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 EPS27674.1 - 0.0096 15.3 0.0 0.021 14.2 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EPS27674.1 - 0.012 15.8 0.0 0.043 14.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EPS27674.1 - 0.067 12.9 0.1 0.17 11.6 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF496 PF04363.12 EPS27674.1 - 0.23 11.5 9.8 1.9 8.6 0.2 3.1 3 0 0 3 3 2 0 Protein of unknown function (DUF496) AAA_11 PF13086.6 EPS27674.1 - 0.48 10.2 0.0 0.48 10.2 0.0 2.9 2 1 0 3 3 2 0 AAA domain Atg14 PF10186.9 EPS27674.1 - 0.55 9.3 5.3 1.8 7.6 5.0 1.8 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 CLZ PF16526.5 EPS27674.1 - 2.9 8.3 10.4 0.65 10.4 5.8 2.4 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels RPN2_C PF18004.1 EPS27674.1 - 5.7 6.8 8.1 14 5.6 8.1 1.6 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain TauD PF02668.16 EPS27675.1 - 1.7e-43 149.4 0.2 3e-43 148.5 0.2 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 EPS27675.1 - 6.6e-13 49.1 0.2 1.6e-12 47.9 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 EPS27675.1 - 0.0019 17.4 0.1 0.0063 15.7 0.1 1.7 1 1 0 1 1 1 1 CsiD MaoC_dehydratas PF01575.19 EPS27676.1 - 1.6e-23 82.6 0.0 2.6e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 EPS27676.1 - 3.1e-07 30.6 0.0 0.0019 18.3 0.0 2.4 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase Methyltransf_25 PF13649.6 EPS27677.1 - 6.5e-12 46.0 0.0 1.4e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPS27677.1 - 2.4e-11 43.7 0.0 3.2e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EPS27677.1 - 8.4e-11 41.8 0.0 1.3e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EPS27677.1 - 6.5e-08 33.1 0.0 1.4e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPS27677.1 - 7.2e-07 29.2 0.0 1.1e-06 28.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EPS27677.1 - 1.3e-05 24.3 0.1 1.9e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 EPS27677.1 - 2.4e-05 23.8 0.0 3.4e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.7 EPS27677.1 - 8.9e-05 22.5 0.0 0.00019 21.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EPS27677.1 - 0.00019 21.0 0.0 0.00032 20.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EPS27677.1 - 0.0019 18.9 0.0 0.0039 17.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 EPS27677.1 - 0.0021 18.2 0.0 0.004 17.3 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 EPS27677.1 - 0.0028 17.4 0.0 0.0041 16.9 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_32 PF13679.6 EPS27677.1 - 0.0083 16.1 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 EPS27677.1 - 0.013 15.4 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase PCMT PF01135.19 EPS27677.1 - 0.026 14.3 0.2 0.044 13.5 0.2 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 EPS27677.1 - 0.033 13.5 0.1 0.077 12.3 0.1 1.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family TehB PF03848.14 EPS27677.1 - 0.037 13.5 0.0 0.074 12.5 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_24 PF13578.6 EPS27677.1 - 0.085 13.9 0.0 0.21 12.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Per1 PF04080.13 EPS27679.1 - 9.3e-103 343.4 17.2 1.2e-102 343.1 17.2 1.1 1 0 0 1 1 1 1 Per1-like family PGM_PMM_I PF02878.16 EPS27680.1 - 1.7e-16 60.2 0.1 2.7e-07 30.4 0.0 2.8 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 EPS27680.1 - 5.9e-12 45.6 0.5 2.2e-11 43.8 0.5 2.1 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 EPS27680.1 - 0.0017 18.6 0.2 0.0071 16.5 0.2 2.0 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EPS27680.1 - 0.0025 18.4 1.0 0.018 15.6 0.6 2.6 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II CinA_KH PF18146.1 EPS27680.1 - 0.088 13.0 0.2 0.26 11.5 0.2 1.8 1 0 0 1 1 1 0 Damage-inducible protein CinA KH domain tRNA-synt_1c PF00749.21 EPS27681.1 - 1.1e-98 330.0 0.0 1.6e-98 329.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EPS27681.1 - 9.1e-31 107.1 0.0 4.5e-30 104.8 0.0 2.1 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), anti-codon binding domain THUMP PF02926.17 EPS27681.1 - 0.13 12.3 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 THUMP domain SNN_transmemb PF09049.10 EPS27681.1 - 0.18 11.8 0.4 0.33 10.9 0.4 1.4 1 0 0 1 1 1 0 Stannin transmembrane F-box-like PF12937.7 EPS27682.1 - 0.0003 20.6 0.4 0.00088 19.1 0.4 1.8 1 0 0 1 1 1 1 F-box-like Pkinase PF00069.25 EPS27684.1 - 1.7e-69 234.1 0.0 2.3e-69 233.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS27684.1 - 9.5e-31 107.0 0.0 1.5e-30 106.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EPS27684.1 - 1.1e-12 48.4 3.5 1.3e-12 48.3 0.3 2.9 3 0 0 3 3 3 1 Protein kinase C terminal domain C2 PF00168.30 EPS27684.1 - 7.2e-09 35.9 0.0 4.4e-07 30.1 0.0 2.5 1 1 0 1 1 1 1 C2 domain Kinase-like PF14531.6 EPS27684.1 - 2.8e-08 33.4 0.0 6.4e-08 32.3 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EPS27684.1 - 4.7e-05 22.5 0.1 7.9e-05 21.8 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EPS27684.1 - 0.0054 16.7 0.0 0.0097 15.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPS27684.1 - 0.086 12.4 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 EPS27684.1 - 0.11 11.9 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EPS27684.1 - 0.13 11.8 0.2 9.5 5.8 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Adeno_E3_15_3 PF03307.14 EPS27684.1 - 0.19 11.7 0.1 0.33 10.9 0.1 1.3 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region CRC_subunit PF08624.10 EPS27685.1 - 3e-51 173.4 0.0 4.4e-51 172.9 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Snf7 PF03357.21 EPS27686.1 - 1.7e-34 118.9 22.0 1.7e-34 118.9 22.0 2.0 1 1 1 2 2 2 1 Snf7 DUF3138 PF11336.8 EPS27686.1 - 0.0014 17.4 5.5 0.0017 17.0 5.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3138) Fibrinogen_C PF00147.18 EPS27686.1 - 0.074 12.8 0.1 0.1 12.4 0.1 1.2 1 0 0 1 1 1 0 Fibrinogen beta and gamma chains, C-terminal globular domain Fmp27_WPPW PF10359.9 EPS27686.1 - 0.24 10.2 9.5 0.29 9.9 9.5 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Phage_lysozyme2 PF18013.1 EPS27686.1 - 0.25 11.4 4.1 0.27 11.2 2.8 1.8 1 1 0 1 1 1 0 Phage tail lysozyme Peptidase_S46 PF10459.9 EPS27686.1 - 0.42 9.2 11.2 0.44 9.1 11.2 1.1 1 0 0 1 1 1 0 Peptidase S46 NuA4 PF09340.10 EPS27686.1 - 1.2 9.1 6.9 0.99 9.3 0.2 3.3 3 0 0 3 3 3 0 Histone acetyltransferase subunit NuA4 Ten1 PF12658.7 EPS27687.1 - 4.3e-40 136.4 0.0 5.1e-40 136.2 0.0 1.1 1 0 0 1 1 1 1 Telomere capping, CST complex subunit MoaE PF02391.17 EPS27687.1 - 0.0052 17.0 0.0 0.019 15.2 0.0 1.8 2 0 0 2 2 2 1 MoaE protein Ten1_2 PF15490.6 EPS27687.1 - 0.0067 16.1 0.0 0.011 15.4 0.0 1.4 1 1 0 1 1 1 1 Telomere-capping, CST complex subunit MFS_1 PF07690.16 EPS27688.1 - 8.3e-42 143.4 31.8 8.2e-41 140.1 29.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS27688.1 - 4.7e-13 48.8 11.7 4.7e-13 48.8 11.7 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EPS27688.1 - 1.1e-07 30.7 4.7 1.1e-07 30.7 4.7 1.8 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 EPS27688.1 - 0.00042 19.3 1.0 0.00083 18.3 1.0 1.5 1 0 0 1 1 1 1 MFS_1 like family BNIP3 PF06553.12 EPS27688.1 - 0.023 14.4 1.5 0.038 13.7 1.5 1.3 1 0 0 1 1 1 0 BNIP3 3Beta_HSD PF01073.19 EPS27689.1 - 3.5e-24 85.3 0.0 1.2e-23 83.6 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EPS27689.1 - 1e-11 44.8 0.0 2.3e-11 43.6 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EPS27689.1 - 3.2e-09 36.4 0.1 1.2e-08 34.4 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.15 EPS27689.1 - 0.00018 20.8 0.0 0.00033 19.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EPS27689.1 - 0.00051 20.0 0.0 0.00089 19.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 EPS27689.1 - 0.00061 19.0 0.0 0.022 13.9 0.0 2.3 2 0 0 2 2 2 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EPS27689.1 - 0.0018 17.7 0.0 0.0036 16.8 0.0 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 EPS27689.1 - 0.0033 17.4 1.4 0.042 13.8 1.4 2.3 1 1 0 1 1 1 1 KR domain BCAS2 PF05700.11 EPS27690.1 - 1.5e-66 224.0 3.6 1.7e-66 223.9 3.6 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Ceramidase_alk PF04734.13 EPS27691.1 - 3.4e-213 708.9 0.0 4e-213 708.6 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 EPS27691.1 - 6.8e-59 198.5 0.1 1.1e-58 197.8 0.1 1.3 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal Zn_clus PF00172.18 EPS27694.1 - 6.4e-08 32.6 10.7 6.4e-08 32.6 10.7 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPS27694.1 - 0.013 14.6 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain EI24 PF07264.11 EPS27695.1 - 1.1e-16 61.6 15.0 1.5e-16 61.1 15.0 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) HAD_2 PF13419.6 EPS27696.1 - 1.1e-09 38.7 0.0 2.5e-09 37.5 0.0 1.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EPS27696.1 - 6e-06 26.2 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EPS27696.1 - 1.5e-05 25.4 0.0 9.5e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TTRAP PF14203.6 EPS27696.1 - 0.081 12.9 0.1 0.21 11.6 0.1 1.7 1 0 0 1 1 1 0 Putative tranposon-transfer assisting protein FA_desaturase PF00487.24 EPS27697.1 - 6.9e-18 65.4 9.8 1.2e-17 64.7 9.8 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EPS27697.1 - 3.3e-14 52.8 0.0 7.2e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain ELO PF01151.18 EPS27698.1 - 1.5e-61 208.2 8.3 1.7e-61 207.9 8.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF4267 PF14087.6 EPS27698.1 - 0.072 13.2 0.3 9 6.4 0.3 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4267) HNH PF01844.23 EPS27699.1 - 0.038 14.2 2.0 0.079 13.2 2.0 1.5 1 0 0 1 1 1 0 HNH endonuclease GTP_EFTU PF00009.27 EPS27700.1 - 9.9e-31 106.8 2.8 4.6e-29 101.3 2.8 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EPS27700.1 - 7.3e-30 103.2 0.3 2e-29 101.8 0.3 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 IF2_N PF04760.15 EPS27700.1 - 9.4e-12 44.6 0.0 2.3e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.23 EPS27700.1 - 2.7e-09 37.1 0.1 6.2e-09 35.9 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase zf-RanBP PF00641.18 EPS27700.1 - 1.1e-05 24.7 2.5 1.1e-05 24.7 2.5 2.7 2 1 0 2 2 2 1 Zn-finger in Ran binding protein and others GTP_EFTU_D2 PF03144.25 EPS27700.1 - 0.00022 21.5 0.7 0.13 12.7 0.1 2.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 SRPRB PF09439.10 EPS27700.1 - 0.00084 18.8 0.0 0.0022 17.5 0.0 1.7 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EPS27700.1 - 0.00088 19.2 0.6 0.075 12.9 0.1 2.6 1 1 1 2 2 2 1 RsgA GTPase Arf PF00025.21 EPS27700.1 - 0.0015 18.0 0.0 0.0031 17.0 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 EPS27700.1 - 0.06 13.1 0.1 0.19 11.5 0.1 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 EPS27700.1 - 0.14 11.6 0.1 0.34 10.4 0.1 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B TackOD1 PF18551.1 EPS27700.1 - 0.19 11.4 8.7 2.3 7.8 1.9 2.4 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 zf-C3HC4_3 PF13920.6 EPS27700.1 - 0.85 9.5 10.5 0.27 11.1 2.5 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 EPS27700.1 - 0.86 9.7 10.8 3.8 7.6 10.8 2.0 1 1 1 2 2 2 0 Double zinc ribbon DUF35_N PF12172.8 EPS27700.1 - 2.9 7.9 15.5 4.1 7.4 3.8 2.6 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF5523 PF17661.1 EPS27700.1 - 3 7.5 19.1 0.019 14.6 8.5 2.4 3 0 0 3 3 3 0 Family of unknown function (DUF5523) Mito_carr PF00153.27 EPS27701.1 - 1.9e-59 197.6 3.6 3.4e-21 74.9 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Fungal_trans PF04082.18 EPS27702.1 - 3.7e-06 26.2 0.0 8e-06 25.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS27702.1 - 2.5e-05 24.3 2.8 5.9e-05 23.1 2.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EPS27703.1 - 2.9e-33 115.3 23.1 3.6e-33 114.9 23.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_31 PF01055.26 EPS27704.1 - 3e-92 310.1 0.1 4.1e-92 309.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EPS27704.1 - 2.6e-12 46.9 0.0 7.8e-12 45.3 0.0 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like DUF5110 PF17137.4 EPS27704.1 - 0.037 14.3 0.0 0.087 13.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) Ribosomal_S2 PF00318.20 EPS27705.1 - 1.2e-66 224.0 0.2 8.1e-66 221.3 0.2 1.9 1 1 0 1 1 1 1 Ribosomal protein S2 Rick_17kDa_Anti PF05433.15 EPS27706.1 - 3.1e-06 26.9 14.8 6e-06 26.0 14.8 1.5 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.6 EPS27706.1 - 0.011 15.7 14.1 0.03 14.3 14.1 1.8 1 0 0 1 1 1 0 Glycine zipper His_Phos_1 PF00300.22 EPS27708.1 - 0.05 13.3 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Git3 PF11710.8 EPS27709.1 - 7.4e-23 81.4 16.3 7.4e-23 81.4 16.3 1.7 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 EPS27709.1 - 2.4e-09 37.1 0.1 2.4e-09 37.1 0.1 2.6 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term 2OG-FeII_Oxy_2 PF13532.6 EPS27710.1 - 2.6e-15 57.1 0.0 3.2e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CRAL_TRIO PF00650.20 EPS27711.1 - 8e-38 129.7 0.0 1.2e-37 129.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EPS27711.1 - 1.5e-09 37.9 0.1 4.8e-09 36.3 0.1 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EPS27711.1 - 0.00016 21.9 0.0 0.0003 21.0 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF2625 PF10946.8 EPS27711.1 - 0.056 12.5 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF2625 p450 PF00067.22 EPS27712.1 - 2.6e-64 217.7 0.0 3.6e-64 217.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 EPS27713.1 - 3.9e-13 49.0 0.6 8.3e-13 48.0 0.6 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.8 EPS27715.1 - 4.1e-06 25.9 0.0 7.9e-06 24.9 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS27715.1 - 0.039 14.1 13.3 0.064 13.4 13.3 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain PBP_N PF17093.5 EPS27717.1 - 0.03 14.6 0.9 0.03 14.6 0.9 1.6 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus SURF6 PF04935.12 EPS27718.1 - 4.6e-50 170.2 35.6 4.6e-50 170.2 35.6 4.7 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.6 EPS27718.1 - 2.5e-19 69.6 1.4 2.5e-19 69.6 1.4 9.3 7 2 0 7 7 7 1 60S ribosome biogenesis protein Rrp14 Fer4 PF00037.27 EPS27720.1 - 3.8e-14 51.8 15.9 3.5e-08 32.9 4.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EPS27720.1 - 4.8e-13 49.5 10.5 7.2e-13 48.9 10.5 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 EPS27720.1 - 1.5e-10 41.8 8.6 1.4e-05 25.9 0.8 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 EPS27720.1 - 2.2e-10 40.5 21.8 3.8e-07 30.1 12.5 2.0 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 EPS27720.1 - 7.9e-10 38.7 21.1 5.2e-08 32.9 10.8 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 EPS27720.1 - 1.4e-09 37.9 5.9 0.00011 22.2 0.4 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 EPS27720.1 - 1e-08 35.5 3.2 0.00018 21.9 0.2 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 EPS27720.1 - 1.6e-06 27.9 17.5 0.00038 20.4 5.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 EPS27720.1 - 4.8e-06 26.3 12.5 0.01 15.9 2.0 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 EPS27720.1 - 1.4e-05 25.2 11.0 0.00028 21.1 1.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 EPS27720.1 - 9.5e-05 22.9 12.0 0.016 15.7 1.9 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 EPS27720.1 - 0.0097 16.1 5.4 0.68 10.2 0.2 2.2 1 1 1 2 2 2 2 c-SKI Smad4 binding domain Fer4_18 PF13746.6 EPS27720.1 - 0.037 14.2 8.9 1.1 9.4 1.5 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_13 PF13370.6 EPS27720.1 - 0.045 14.3 15.4 0.71 10.5 4.3 2.6 2 1 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 EPS27720.1 - 0.063 14.2 15.7 0.11 13.5 3.5 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain ETF_QO PF05187.13 EPS27720.1 - 0.09 12.9 5.9 0.37 10.9 0.6 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 EPS27720.1 - 0.23 12.4 11.3 2.8 8.9 1.8 2.2 1 1 2 3 3 3 0 4Fe-4S dicluster domain DUF4451 PF14616.6 EPS27720.1 - 0.97 9.6 4.2 5 7.3 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4451) PP-binding PF00550.25 EPS27721.1 - 1.4e-10 41.4 0.1 1.8e-10 41.0 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 EPS27721.1 - 4.7e-06 26.7 0.1 6.7e-06 26.2 0.1 1.1 1 0 0 1 1 1 1 Acyl-carrier GPP34 PF05719.11 EPS27722.1 - 8.1e-68 228.5 0.2 1e-67 228.1 0.2 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) DUF2183 PF09949.9 EPS27723.1 - 2.5e-34 117.6 0.1 6e-34 116.3 0.1 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 EPS27723.1 - 0.025 14.1 0.0 0.05 13.1 0.0 1.5 1 1 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) ADH_zinc_N_2 PF13602.6 EPS27724.1 - 1e-05 26.6 0.0 2e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPS27724.1 - 0.0029 17.5 0.0 0.0065 16.3 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ribo_biogen_C PF04034.13 EPS27725.1 - 3.5e-53 178.7 0.1 4.9e-53 178.2 0.1 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 EPS27725.1 - 1.8e-11 43.7 0.7 1.8e-11 43.7 0.7 1.6 2 0 0 2 2 2 1 Possible Fer4-like domain in RNase L inhibitor, RLI CDC45 PF02724.14 EPS27725.1 - 0.97 7.6 18.3 1.2 7.3 18.3 1.1 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 EPS27725.1 - 3.1 7.0 23.8 4.6 6.5 23.8 1.3 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 EPS27725.1 - 4.2 6.7 25.8 6.2 6.1 25.8 1.3 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 EPS27725.1 - 5.8 4.9 28.2 7.7 4.5 28.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi VHS PF00790.19 EPS27726.1 - 1.2e-43 148.4 0.0 4e-43 146.6 0.0 1.9 2 0 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.20 EPS27726.1 - 2.3e-21 76.2 0.1 5.6e-21 74.9 0.1 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.14 EPS27726.1 - 3.3e-20 72.2 0.2 1.2e-19 70.4 0.0 2.1 2 0 0 2 2 2 1 GAT domain GGA_N-GAT PF18308.1 EPS27726.1 - 2.9e-10 39.6 0.1 2.9e-07 30.0 0.1 2.7 2 0 0 2 2 2 2 GGA N-GAT domain Mei5 PF10376.9 EPS27726.1 - 0.069 13.0 1.7 0.14 12.0 1.7 1.5 1 0 0 1 1 1 0 Double-strand recombination repair protein DUF349 PF03993.12 EPS27726.1 - 1.7 9.0 6.0 0.37 11.1 0.4 2.5 1 1 1 2 2 2 0 Domain of Unknown Function (DUF349) CBS PF00571.28 EPS27728.1 - 1.4e-21 76.7 4.7 1.7e-06 28.4 0.0 5.3 5 0 0 5 5 5 4 CBS domain Pex14_N PF04695.13 EPS27728.1 - 6.4 7.4 11.5 1.3 9.6 1.7 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peptidase_C14 PF00656.22 EPS27730.1 - 8.6e-63 212.6 0.0 1.1e-62 212.3 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Cpn60_TCP1 PF00118.24 EPS27731.1 - 1.6e-152 508.6 4.5 1.9e-152 508.4 4.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rep_fac_C PF08542.11 EPS27731.1 - 0.013 15.9 0.0 1.5 9.3 0.1 2.7 2 0 0 2 2 2 0 Replication factor C C-terminal domain Beta_helix_2 PF18835.1 EPS27731.1 - 0.023 14.4 0.4 1.4 8.7 0.4 2.7 2 0 0 2 2 2 0 Beta helix repeat of Inulin fructotransferase FtsA PF14450.6 EPS27731.1 - 0.16 12.4 1.3 0.37 11.2 1.0 1.8 1 1 0 1 1 1 0 Cell division protein FtsA zf-H2C2 PF09337.10 EPS27732.1 - 2.9e-16 59.4 2.0 5.4e-16 58.5 2.0 1.5 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 EPS27732.1 - 8.4e-11 41.8 0.6 1.7e-10 40.8 0.6 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 EPS27732.1 - 4.3e-06 27.0 0.0 7.6e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 EPS27732.1 - 0.0055 17.4 0.0 0.018 15.7 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPS27732.1 - 0.06 13.3 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_4 PF13420.7 EPS27732.1 - 0.065 13.4 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FlxA PF14282.6 EPS27732.1 - 1.1 9.3 5.0 0.17 11.9 0.6 1.9 2 0 0 2 2 2 0 FlxA-like protein LANC_like PF05147.13 EPS27733.1 - 1.6e-25 89.4 0.0 1.8e-23 82.7 0.0 2.4 2 1 0 2 2 2 1 Lanthionine synthetase C-like protein BAG PF02179.16 EPS27734.1 - 1.2e-17 64.1 0.1 3.1e-17 62.8 0.1 1.7 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.23 EPS27734.1 - 0.00012 21.7 0.0 0.00025 20.7 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Zn_clus PF00172.18 EPS27735.1 - 0.0019 18.3 11.8 0.0038 17.3 11.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gly_transf_sug PF04488.15 EPS27736.1 - 1.1e-14 54.9 0.0 2e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 EPS27736.1 - 0.0082 15.5 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein RTA1 PF04479.13 EPS27737.1 - 1.3e-71 240.5 6.9 1.3e-71 240.5 6.9 1.5 1 1 0 1 1 1 1 RTA1 like protein Abhydrolase_9_N PF15420.6 EPS27737.1 - 3.1 7.7 11.3 0.062 13.3 1.9 2.4 2 1 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Glyco_hydro_11 PF00457.17 EPS27738.1 - 5.8e-49 166.1 17.1 9.5e-49 165.4 17.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 CBM_1 PF00734.18 EPS27738.1 - 1.6e-10 40.8 16.6 3.8e-10 39.6 14.8 2.7 2 0 0 2 2 2 1 Fungal cellulose binding domain Glutaredoxin PF00462.24 EPS27741.1 - 4.7e-20 71.6 0.0 1e-19 70.5 0.0 1.5 2 0 0 2 2 2 1 Glutaredoxin DUF836 PF05768.14 EPS27741.1 - 0.0016 18.8 0.3 0.0029 18.0 0.3 1.6 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) TraF PF13728.6 EPS27741.1 - 0.0093 15.8 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin PF00085.20 EPS27741.1 - 0.0099 15.9 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EPS27741.1 - 0.012 16.0 0.1 0.02 15.4 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain DSBA PF01323.20 EPS27741.1 - 0.048 13.4 0.1 0.13 12.1 0.1 1.7 1 1 0 1 1 1 0 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 EPS27741.1 - 0.076 13.2 0.6 4.1 7.5 0.1 2.1 1 1 1 2 2 2 0 Thioredoxin Chalcone_2 PF16035.5 EPS27742.1 - 1.5e-82 276.3 0.0 1.9e-82 276.0 0.0 1.1 1 0 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 EPS27742.1 - 0.00031 20.9 0.1 0.0012 19.0 0.0 1.9 2 1 0 2 2 2 1 Chalcone isomerase-like Ribosomal_L26 PF16906.5 EPS27743.1 - 1.3e-37 128.1 0.8 1.6e-37 127.8 0.8 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 EPS27743.1 - 1.3e-06 28.2 1.2 2.5e-06 27.2 1.2 1.5 1 0 0 1 1 1 1 KOW motif Bac_rhamnosid6H PF17389.2 EPS27744.1 - 8.4e-18 64.7 3.6 5.5e-14 52.2 3.0 2.1 1 1 1 2 2 2 2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_C PF17390.2 EPS27744.1 - 2.8e-09 36.7 0.0 7.1e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Bac_rhamnosid PF05592.11 EPS27744.1 - 0.00052 19.9 0.0 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Trehalase PF01204.18 EPS27744.1 - 0.00068 18.6 0.0 0.001 18.0 0.0 1.2 1 0 0 1 1 1 1 Trehalase DUF4981 PF16353.5 EPS27744.1 - 0.024 15.1 0.0 0.064 13.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function(DUF4981) Glyco_hydro_28 PF00295.17 EPS27745.1 - 1.1e-43 149.5 4.9 5.8e-43 147.2 4.9 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Fe-ADH PF00465.19 EPS27746.1 - 2.1e-63 214.4 0.0 4.4e-62 210.0 0.0 1.9 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EPS27746.1 - 1.3e-08 34.8 0.6 0.00026 20.8 0.1 2.5 2 1 0 3 3 3 2 Iron-containing alcohol dehydrogenase Importin_rep_4 PF18808.1 EPS27747.1 - 2.4e-33 114.3 1.9 3e-32 110.8 1.0 3.3 2 0 0 2 2 2 1 Importin repeat Importin_rep_5 PF18816.1 EPS27747.1 - 7.2e-21 74.2 0.8 7.2e-21 74.2 0.8 2.3 2 0 0 2 2 1 1 Importin repeat HEAT_EZ PF13513.6 EPS27747.1 - 4.4e-20 71.8 19.5 1e-10 41.9 0.5 9.1 8 1 1 9 9 8 3 HEAT-like repeat HEAT_2 PF13646.6 EPS27747.1 - 5.3e-16 58.8 13.0 5.6e-05 23.4 0.1 8.5 5 2 3 8 8 8 2 HEAT repeats HEAT PF02985.22 EPS27747.1 - 2.9e-15 55.1 17.3 0.0028 17.8 0.0 12.1 14 0 0 14 14 13 3 HEAT repeat Importin_rep_6 PF18829.1 EPS27747.1 - 9.9e-13 48.2 4.4 1.7e-12 47.4 1.8 2.8 2 0 0 2 2 2 1 Importin repeat 6 Vac14_Fab1_bd PF12755.7 EPS27747.1 - 1.2e-09 38.7 0.0 0.0028 18.2 0.0 6.5 4 2 3 7 7 6 1 Vacuolar 14 Fab1-binding region MMS19_C PF12460.8 EPS27747.1 - 5.2e-09 35.7 9.3 1.2e-06 28.0 0.2 5.5 5 1 1 6 6 6 2 RNAPII transcription regulator C-terminal Cnd1 PF12717.7 EPS27747.1 - 4.1e-08 33.4 1.8 0.1 12.6 0.0 5.6 3 2 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.8 EPS27747.1 - 2.2e-07 30.9 0.6 0.32 10.9 0.0 6.4 5 2 2 7 7 7 1 Domain of unknown function (DUF3385) RIX1 PF08167.12 EPS27747.1 - 1.9e-06 27.8 0.9 0.0037 17.0 0.0 4.5 3 2 1 4 4 4 1 rRNA processing/ribosome biogenesis Adaptin_N PF01602.20 EPS27747.1 - 1.4e-05 23.9 0.8 0.0041 15.8 0.1 3.6 3 1 0 3 3 3 1 Adaptin N terminal region DRIM PF07539.12 EPS27747.1 - 2.8e-05 22.7 1.8 0.054 11.8 0.2 4.0 2 2 1 3 3 3 2 Down-regulated in metastasis CLASP_N PF12348.8 EPS27747.1 - 4.9e-05 23.0 0.4 0.45 10.0 0.0 5.3 5 3 1 6 6 6 1 CLASP N terminal Arm PF00514.23 EPS27747.1 - 6.7e-05 22.8 3.0 0.65 10.1 0.0 4.6 4 0 0 4 4 3 2 Armadillo/beta-catenin-like repeat IBN_N PF03810.19 EPS27747.1 - 0.0018 18.2 0.1 0.089 12.7 0.0 3.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF4042 PF13251.6 EPS27747.1 - 0.0032 17.2 0.1 7.1 6.3 0.0 4.4 4 0 0 4 4 4 1 Domain of unknown function (DUF4042) DNA_alkylation PF08713.11 EPS27747.1 - 0.036 13.8 0.0 0.25 11.0 0.0 2.5 1 0 0 1 1 1 0 DNA alkylation repair enzyme RTP1_C1 PF10363.9 EPS27747.1 - 0.039 14.1 0.6 87 3.4 0.1 5.3 6 1 1 8 8 7 0 Required for nuclear transport of RNA pol II C-terminus 1 Rif1_N PF12231.8 EPS27747.1 - 0.04 12.9 0.7 0.16 10.9 0.0 2.5 2 1 1 3 3 3 0 Rap1-interacting factor 1 N terminal Cnd3 PF12719.7 EPS27747.1 - 0.06 12.5 0.1 16 4.6 0.0 3.8 3 1 0 3 3 3 0 Nuclear condensing complex subunits, C-term domain Telomere_reg-2 PF10193.9 EPS27747.1 - 0.27 11.7 2.1 3.8 8.0 0.1 3.5 2 1 1 3 3 3 0 Telomere length regulation protein V-ATPase_H_N PF03224.14 EPS27747.1 - 1.5 8.0 4.5 4.3 6.5 0.0 3.3 3 1 1 4 4 4 0 V-ATPase subunit H CBS PF00571.28 EPS27748.1 - 7.4e-36 122.4 5.5 2.2e-09 37.6 0.0 5.2 5 0 0 5 5 5 4 CBS domain PB1 PF00564.24 EPS27748.1 - 1e-09 38.2 0.0 2.9e-09 36.7 0.0 1.9 1 0 0 1 1 1 1 PB1 domain Ribosomal_S26e PF01283.19 EPS27749.1 - 9.7e-53 177.2 8.2 1.1e-52 177.0 8.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e zf_CopZ PF18423.1 EPS27749.1 - 0.026 14.5 0.4 0.066 13.2 0.0 1.8 2 0 0 2 2 2 0 Zinc binding domain F-box-like PF12937.7 EPS27750.1 - 2e-05 24.4 1.3 2e-05 24.4 1.3 2.0 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.6 EPS27750.1 - 0.0011 18.8 2.3 2.3 8.5 0.0 3.7 5 0 0 5 5 5 2 Leucine Rich repeat LRR_4 PF12799.7 EPS27750.1 - 0.026 14.9 0.7 31 5.2 0.2 4.1 3 1 0 4 4 4 0 Leucine Rich repeats (2 copies) F-box PF00646.33 EPS27750.1 - 0.031 14.2 0.2 0.031 14.2 0.2 2.7 3 0 0 3 3 3 0 F-box domain F-box_5 PF18511.1 EPS27750.1 - 0.09 12.4 2.5 0.44 10.2 2.6 2.2 1 1 0 1 1 1 0 F-box LMBR1 PF04791.16 EPS27751.1 - 4.2e-130 435.1 5.4 4.9e-130 434.8 5.4 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein Apolipoprotein PF01442.18 EPS27751.1 - 3.1 7.6 4.9 1.1 9.0 1.0 1.9 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain HTH_46 PF15977.5 EPS27752.1 - 0.022 14.8 0.1 1.5 8.9 0.1 2.6 2 0 0 2 2 2 0 Winged helix-turn-helix DNA binding Med15_fungi PF05397.12 EPS27754.1 - 4.7e-26 91.3 0.1 4.7e-26 91.3 0.1 5.4 5 0 0 5 5 5 2 Mediator complex subunit 15 KIX_2 PF16987.5 EPS27754.1 - 1.9e-09 37.4 0.2 1.9e-09 37.4 0.2 3.8 5 1 1 6 6 6 1 KIX domain MPDZ_u10 PF16667.5 EPS27755.1 - 0.094 13.6 4.5 3.6 8.6 1.5 2.4 2 0 0 2 2 2 0 Unstructured region 10 on multiple PDZ protein EamA PF00892.20 EPS27756.1 - 4e-12 46.5 21.5 4.4e-06 26.9 2.5 2.4 2 0 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 EPS27756.1 - 1.1e-09 37.9 0.1 2e-09 37.1 0.1 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.16 EPS27756.1 - 0.00036 20.0 4.2 0.00039 19.9 0.2 2.3 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.11 EPS27756.1 - 0.001 18.3 8.9 0.0013 18.0 8.1 1.5 2 0 0 2 2 2 1 UAA transporter family CRT-like PF08627.10 EPS27756.1 - 0.35 9.8 11.1 0.17 10.8 4.8 2.8 2 1 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like DUF5472 PF17566.2 EPS27756.1 - 0.36 10.8 1.5 2.5 8.1 0.3 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5472) Adaptin_N PF01602.20 EPS27757.1 - 8.2e-141 470.1 0.9 9.6e-141 469.9 0.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 EPS27757.1 - 2.4e-20 72.9 0.0 5.3e-20 71.8 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 EPS27757.1 - 3.4e-07 30.4 8.2 0.00062 19.8 0.0 4.7 3 2 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EPS27757.1 - 1e-06 29.0 1.3 0.5 10.8 0.0 4.3 3 2 1 4 4 4 2 HEAT repeats HEAT PF02985.22 EPS27757.1 - 0.0023 18.0 1.7 6.7 7.3 0.1 4.5 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 EPS27757.1 - 0.0045 17.4 0.6 26 5.4 0.0 5.7 4 1 3 7 7 7 0 HEAT-like repeat Arm PF00514.23 EPS27757.1 - 0.018 15.1 1.6 58 3.9 0.1 5.8 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat partial_CstF PF15861.5 EPS27757.1 - 0.026 14.3 0.0 0.078 12.8 0.0 1.8 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain RICTOR_M PF14666.6 EPS27757.1 - 0.04 13.7 0.4 0.31 10.8 0.0 2.6 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, middle domain SprA_N PF14349.6 EPS27757.1 - 0.14 11.0 0.1 0.24 10.2 0.1 1.2 1 0 0 1 1 1 0 Motility related/secretion protein Cohesin_HEAT PF12765.7 EPS27757.1 - 0.31 11.4 1.6 0.57 10.5 0.2 2.3 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion MBOAT PF03062.19 EPS27758.1 - 1.3e-38 133.2 17.7 3.6e-38 131.8 17.7 1.7 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 EPS27758.1 - 0.0071 16.6 3.8 0.017 15.4 3.8 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF1746 PF08508.10 EPS27758.1 - 0.2 12.0 2.9 1.6 9.1 0.0 2.9 3 0 0 3 3 3 0 Fungal domain of unknown function (DUF1746) DnaJ PF00226.31 EPS27760.1 - 7.4e-21 74.0 0.3 2e-20 72.7 0.3 1.8 1 0 0 1 1 1 1 DnaJ domain Yqai PF09466.10 EPS27761.1 - 0.19 12.1 0.0 0.28 11.5 0.0 1.5 1 1 0 1 1 1 0 Hypothetical protein Yqai Ribosomal_L13 PF00572.18 EPS27763.1 - 8.5e-12 45.4 0.1 8.6e-10 38.9 0.0 2.4 2 1 0 2 2 2 1 Ribosomal protein L13 DSBA PF01323.20 EPS27763.1 - 0.069 12.9 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 DSBA-like thioredoxin domain GFO_IDH_MocA PF01408.22 EPS27764.1 - 5e-21 75.8 0.1 8.9e-21 74.9 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold AMP-binding PF00501.28 EPS27765.1 - 2.7e-75 253.6 0.0 3.2e-75 253.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EPS27765.1 - 8e-19 68.4 0.1 2.9e-18 66.6 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Ins134_P3_kin_N PF17927.1 EPS27765.1 - 0.15 12.5 0.2 0.33 11.4 0.2 1.5 1 0 0 1 1 1 0 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain LRR_6 PF13516.6 EPS27766.1 - 1.6e-13 49.5 19.6 0.31 11.2 0.0 11.7 13 0 0 13 13 13 5 Leucine Rich repeat F-box-like PF12937.7 EPS27766.1 - 3.2e-12 46.1 2.6 1.2e-11 44.4 0.1 2.9 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.7 EPS27766.1 - 1.3e-11 44.5 10.2 0.97 9.9 0.3 7.9 5 1 2 8 8 8 4 Leucine Rich repeats (2 copies) F-box PF00646.33 EPS27766.1 - 0.00055 19.8 0.2 0.0022 17.8 0.2 2.2 1 0 0 1 1 1 1 F-box domain LRR_8 PF13855.6 EPS27766.1 - 0.0085 15.8 4.7 0.4 10.5 0.0 5.2 4 3 1 5 5 5 1 Leucine rich repeat Preseq_ALAS PF09029.10 EPS27766.1 - 0.33 11.4 2.5 22 5.6 0.0 3.5 2 1 1 3 3 3 0 5-aminolevulinate synthase presequence Peptidase_M28 PF04389.17 EPS27767.1 - 7.3e-34 117.2 0.0 1.1e-33 116.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EPS27767.1 - 0.00027 20.7 0.0 0.00044 20.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF3767 PF12597.8 EPS27767.1 - 0.21 11.4 0.6 0.41 10.5 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) Med10 PF09748.9 EPS27770.1 - 2.7e-43 146.8 0.0 3.2e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3877 PF12993.7 EPS27770.1 - 0.022 14.6 0.0 0.043 13.7 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) NPV_P10 PF05531.12 EPS27770.1 - 0.1 13.1 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein adh_short PF00106.25 EPS27771.1 - 1e-09 38.1 0.0 2.9e-09 36.7 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS27771.1 - 6.4e-05 22.6 0.0 0.00016 21.4 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPS27771.1 - 0.00011 22.2 0.0 0.0002 21.3 0.0 1.5 1 0 0 1 1 1 1 KR domain DUF1173 PF06666.11 EPS27771.1 - 0.12 11.3 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1173) Pkinase PF00069.25 EPS27772.1 - 2.1e-40 138.8 0.0 2.8e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS27772.1 - 1e-31 110.2 0.0 1.4e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EPS27772.1 - 0.022 14.1 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like PB1 PF00564.24 EPS27772.1 - 0.17 11.9 0.1 0.42 10.6 0.1 1.6 1 0 0 1 1 1 0 PB1 domain DnaJ PF00226.31 EPS27774.1 - 3e-29 100.9 6.6 7.2e-29 99.7 3.6 2.5 2 0 0 2 2 2 1 DnaJ domain TPR_1 PF00515.28 EPS27774.1 - 1.5e-23 81.5 13.9 3e-08 33.1 0.7 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.17 EPS27774.1 - 2.4e-22 77.2 13.9 9.4e-07 28.5 0.4 5.9 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.6 EPS27774.1 - 1.9e-18 66.8 4.3 8e-08 32.8 0.4 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 EPS27774.1 - 5.6e-14 52.4 17.3 9.5e-07 29.2 2.4 5.3 3 3 3 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 EPS27774.1 - 2.7e-13 49.5 7.0 0.00028 21.4 0.1 5.8 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 EPS27774.1 - 6.7e-12 44.9 9.8 0.0021 17.7 0.3 5.7 5 0 0 5 5 5 4 TPR repeat TPR_7 PF13176.6 EPS27774.1 - 8.1e-12 44.3 5.8 0.023 14.7 0.0 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EPS27774.1 - 1.2e-11 43.8 10.3 8.3e-06 25.6 0.3 5.4 5 0 0 5 5 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EPS27774.1 - 2e-08 34.4 4.7 0.03 14.5 0.7 4.2 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EPS27774.1 - 3.7e-08 33.2 8.3 0.0025 18.1 0.4 4.9 5 0 0 5 5 4 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EPS27774.1 - 8.5e-08 32.1 6.1 0.012 15.6 0.1 3.8 3 1 1 4 4 3 3 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 EPS27774.1 - 9.3e-08 32.3 8.1 0.0012 19.0 1.4 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 EPS27774.1 - 5e-06 26.8 14.7 0.041 14.5 0.2 6.5 6 1 1 7 7 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 EPS27774.1 - 2.1e-05 24.6 1.7 0.44 10.7 0.1 3.3 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_15 PF13429.6 EPS27774.1 - 0.00016 21.0 3.5 0.23 10.6 0.1 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 EPS27774.1 - 0.0058 17.1 2.8 1.9 8.9 0.0 3.1 2 1 2 4 4 3 2 Alkyl sulfatase dimerisation RPT PF13446.6 EPS27774.1 - 0.0077 16.1 1.3 0.23 11.4 0.0 3.3 3 0 0 3 3 2 1 A repeated domain in UCH-protein DUF2989 PF11207.8 EPS27774.1 - 0.044 13.5 1.2 0.35 10.6 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2989) DUF3808 PF10300.9 EPS27774.1 - 0.057 12.2 0.1 8.5 5.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3808) DUF3856 PF12968.7 EPS27774.1 - 0.06 13.4 6.2 19 5.3 1.6 4.8 3 2 1 4 4 4 0 Domain of Unknown Function (DUF3856) TPR_10 PF13374.6 EPS27774.1 - 0.079 12.9 11.2 3.1 7.8 0.6 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 EPS27774.1 - 0.087 12.3 2.2 18 4.9 0.0 3.9 4 0 0 4 4 4 0 SHNi-TPR HHH_8 PF14716.6 EPS27774.1 - 0.1 13.0 3.4 22 5.5 0.1 3.8 3 0 0 3 3 3 0 Helix-hairpin-helix domain TPR_20 PF14561.6 EPS27774.1 - 0.44 10.9 3.2 3.5 8.0 0.1 3.0 1 1 1 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.12 EPS27774.1 - 0.58 10.2 3.2 2.8 8.0 0.1 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat DUF627 PF04781.12 EPS27774.1 - 0.94 9.5 3.8 0.7 9.9 0.6 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF627) BTAD PF03704.17 EPS27774.1 - 1.2 9.6 9.7 2.3 8.6 2.0 3.4 2 2 0 2 2 2 0 Bacterial transcriptional activator domain SPO22 PF08631.10 EPS27774.1 - 4.2 6.8 7.3 15 4.9 0.1 3.3 2 1 2 4 4 4 0 Meiosis protein SPO22/ZIP4 like MIT PF04212.18 EPS27774.1 - 7.1 6.8 13.4 1.3 9.1 0.2 4.0 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain Pkinase PF00069.25 EPS27778.1 - 4e-64 216.5 0.0 4.9e-64 216.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS27778.1 - 6.8e-36 123.9 0.0 9.1e-36 123.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EPS27778.1 - 7e-07 28.8 0.0 1.1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EPS27778.1 - 0.00017 20.5 0.0 0.00026 19.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EPS27778.1 - 0.045 13.4 0.0 3.9 7.0 0.0 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Sec39 PF08314.11 EPS27779.1 - 5.8e-274 911.2 4.9 6.6e-274 911.0 4.9 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Ndufs5 PF10200.9 EPS27780.1 - 0.00021 21.5 0.1 0.00026 21.2 0.1 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.8 EPS27780.1 - 0.0017 18.7 1.5 0.0099 16.2 1.5 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3128) CHCH PF06747.13 EPS27780.1 - 0.0061 16.7 0.2 0.0098 16.0 0.2 1.3 1 0 0 1 1 1 1 CHCH domain COX6B PF02297.17 EPS27780.1 - 0.035 14.3 0.3 0.054 13.7 0.3 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb NYD-SP28_assoc PF14775.6 EPS27780.1 - 0.14 12.3 0.1 0.22 11.6 0.1 1.3 1 0 0 1 1 1 0 Sperm tail C-terminal domain UPF0203 PF05254.12 EPS27780.1 - 0.2 11.9 1.8 0.31 11.3 1.8 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) DUF3535 PF12054.8 EPS27781.1 - 1.4e-124 416.7 0.0 1.8e-123 413.1 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 EPS27781.1 - 1.4e-62 211.5 0.0 3.2e-62 210.3 0.0 1.5 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EPS27781.1 - 5.5e-19 68.5 0.0 1.5e-18 67.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 EPS27781.1 - 1.9e-12 46.3 19.5 0.076 13.3 0.0 10.1 11 0 0 11 11 9 4 HEAT repeat HEAT_2 PF13646.6 EPS27781.1 - 5e-07 30.0 11.6 0.00094 19.5 0.6 6.3 6 1 1 7 7 7 1 HEAT repeats Vac14_Fab1_bd PF12755.7 EPS27781.1 - 3.9e-05 24.2 0.0 0.67 10.6 0.0 4.1 3 1 0 4 4 4 2 Vacuolar 14 Fab1-binding region TAF6_C PF07571.13 EPS27781.1 - 0.00033 20.9 0.1 1.6 9.1 0.0 5.3 6 0 0 6 6 6 1 TAF6 C-terminal HEAT repeat domain Cnd1 PF12717.7 EPS27781.1 - 0.0011 19.0 0.0 1.5 8.8 0.0 4.7 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EPS27781.1 - 0.16 11.5 0.2 64 3.0 0.1 3.7 2 1 1 3 3 3 0 CLASP N terminal U3_snoRNA_assoc PF08297.11 EPS27781.1 - 0.32 11.7 1.9 0.48 11.2 0.2 2.2 2 0 0 2 2 1 0 U3 snoRNA associated HEAT_EZ PF13513.6 EPS27781.1 - 0.51 10.9 20.7 1.3 9.6 0.0 7.4 8 0 0 8 8 8 0 HEAT-like repeat Ad_cyc_g-alpha PF08509.11 EPS27782.1 - 0.09 12.5 0.0 0.31 10.8 0.0 1.9 1 0 0 1 1 1 0 Adenylate cyclase G-alpha binding domain Abhydrolase_2 PF02230.16 EPS27783.1 - 7.4e-28 97.8 0.0 5.9e-20 72.0 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EPS27783.1 - 0.00088 18.8 0.0 0.0032 17.0 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EPS27783.1 - 0.0071 15.6 0.1 0.11 11.7 0.0 2.2 1 1 0 2 2 2 1 Serine aminopeptidase, S33 LIP PF03583.14 EPS27783.1 - 0.03 13.7 0.0 0.2 10.9 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase Esterase_phd PF10503.9 EPS27783.1 - 0.08 12.4 0.0 9.9 5.6 0.0 2.2 2 0 0 2 2 2 0 Esterase PHB depolymerase Qua1 PF16274.5 EPS27783.1 - 0.17 11.8 0.0 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Qua1 domain DUF2330 PF10092.9 EPS27783.1 - 0.25 10.4 0.0 0.36 9.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2330) Pro_racemase PF05544.11 EPS27784.1 - 9.8e-123 409.3 0.1 1.1e-122 409.2 0.1 1.0 1 0 0 1 1 1 1 Proline racemase Aa_trans PF01490.18 EPS27785.1 - 4.9e-56 190.2 39.5 5.5e-56 190.0 39.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Erythro_esteras PF05139.14 EPS27786.1 - 2.9e-127 425.2 2.1 3.3e-127 425.0 2.1 1.0 1 0 0 1 1 1 1 Erythromycin esterase Scs3p PF10261.9 EPS27788.1 - 3.5e-69 233.0 1.9 4.7e-69 232.6 1.9 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM ABC_tran PF00005.27 EPS27791.1 - 4.4e-38 130.9 0.0 4.2e-22 79.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EPS27791.1 - 6.5e-15 55.5 8.7 6.5e-15 55.5 8.7 2.7 3 0 0 3 3 3 1 ABC transporter transmembrane region AAA_29 PF13555.6 EPS27791.1 - 3.5e-08 33.1 1.2 0.00067 19.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EPS27791.1 - 6.6e-07 29.9 0.0 0.041 14.3 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EPS27791.1 - 1.8e-06 27.9 0.0 0.026 14.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA PF00004.29 EPS27791.1 - 4.3e-06 27.2 0.0 0.02 15.3 0.0 3.2 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 EPS27791.1 - 8.2e-06 25.9 0.0 0.065 13.3 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_7 PF12775.7 EPS27791.1 - 1.1e-05 25.0 0.0 0.18 11.3 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_22 PF13401.6 EPS27791.1 - 3.3e-05 24.2 0.3 0.27 11.5 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 EPS27791.1 - 3.4e-05 23.9 0.1 0.33 10.9 0.1 3.6 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 EPS27791.1 - 0.00013 21.8 0.0 0.042 13.6 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 EPS27791.1 - 0.00018 21.3 0.0 0.45 10.2 0.0 3.0 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.19 EPS27791.1 - 0.00024 20.6 0.9 1.8 7.9 0.1 3.5 4 0 0 4 4 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EPS27791.1 - 0.00029 20.8 0.1 0.43 10.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 EPS27791.1 - 0.00061 20.0 0.0 0.063 13.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EPS27791.1 - 0.00063 20.1 0.0 0.17 12.3 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.6 EPS27791.1 - 0.0007 19.2 0.3 0.24 11.0 0.1 2.4 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 EPS27791.1 - 0.00073 18.7 0.1 0.65 9.0 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein Zeta_toxin PF06414.12 EPS27791.1 - 0.00081 18.7 0.1 0.15 11.3 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin DUF815 PF05673.13 EPS27791.1 - 0.0013 18.0 0.0 0.3 10.2 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 EPS27791.1 - 0.0015 18.0 0.1 0.87 8.9 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Dynamin_N PF00350.23 EPS27791.1 - 0.0015 18.6 0.3 1.2 9.2 0.1 2.4 2 0 0 2 2 2 1 Dynamin family NACHT PF05729.12 EPS27791.1 - 0.0022 18.0 1.0 3.3 7.6 0.0 3.1 3 0 0 3 3 3 2 NACHT domain AAA_23 PF13476.6 EPS27791.1 - 0.0024 18.4 1.1 0.15 12.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 EPS27791.1 - 0.0028 16.9 0.0 0.17 11.1 0.0 2.4 2 1 0 2 2 2 1 NB-ARC domain Sigma54_activat PF00158.26 EPS27791.1 - 0.0052 16.5 0.0 0.082 12.6 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.6 EPS27791.1 - 0.0097 16.5 0.1 1.4 9.5 0.1 2.7 2 1 0 2 2 2 1 AAA domain cobW PF02492.19 EPS27791.1 - 0.014 15.0 0.3 1.9 8.1 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 EPS27791.1 - 0.014 15.1 0.3 1.4 8.6 0.2 2.7 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 EPS27791.1 - 0.02 15.1 0.1 3.3 8.0 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 EPS27791.1 - 0.022 14.1 0.3 5.1 6.4 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Rad17 PF03215.15 EPS27791.1 - 0.028 14.4 0.2 0.086 12.8 0.2 1.8 1 0 0 1 1 1 0 Rad17 P-loop domain Viral_helicase1 PF01443.18 EPS27791.1 - 0.034 13.9 0.7 0.18 11.6 0.1 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 EPS27791.1 - 0.052 13.5 0.1 12 5.8 0.0 2.4 2 0 0 2 2 2 0 NTPase MCM PF00493.23 EPS27791.1 - 0.083 12.0 0.1 4.1 6.4 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain IstB_IS21 PF01695.17 EPS27791.1 - 0.12 12.1 0.2 13 5.5 0.0 2.9 3 0 0 3 3 2 0 IstB-like ATP binding protein TsaE PF02367.17 EPS27791.1 - 0.13 12.3 0.0 13 5.8 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Glyco_hydro_3_C PF01915.22 EPS27792.1 - 3e-49 167.8 0.0 4.2e-49 167.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EPS27792.1 - 4.2e-37 128.2 0.0 7.4e-37 127.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EPS27792.1 - 1.3e-17 63.7 0.0 3e-17 62.5 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain SBF PF01758.16 EPS27794.1 - 1e-50 172.1 8.1 1e-50 172.1 8.1 2.3 2 1 1 3 3 3 1 Sodium Bile acid symporter family bZIP_1 PF00170.21 EPS27795.1 - 0.0057 16.7 13.9 0.0083 16.2 10.4 2.3 1 1 1 2 2 2 1 bZIP transcription factor FUSC PF04632.12 EPS27795.1 - 1.1 7.7 6.6 1.8 7.0 6.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4748 PF15932.5 EPS27795.1 - 2.8 7.8 4.0 6.4 6.6 4.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) C_Hendra PF16821.5 EPS27795.1 - 9.8 6.0 9.9 0.11 12.4 1.6 2.0 2 0 0 2 2 2 0 C protein from hendra and measles viruses TraD_N PF12615.8 EPS27796.1 - 0.0022 18.7 1.1 0.0048 17.6 1.1 1.6 1 0 0 1 1 1 1 F sex factor protein N terminal Fungal_trans PF04082.18 EPS27797.1 - 2.4e-26 92.4 0.0 4.3e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS27797.1 - 2.9e-09 36.9 11.9 4.7e-09 36.2 11.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Man-6-P_recep PF02157.15 EPS27798.1 - 8.9e-14 51.2 0.0 1.3e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.10 EPS27798.1 - 1.5e-11 44.6 0.0 3.3e-11 43.6 0.0 1.5 1 1 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.18 EPS27798.1 - 2.9e-07 30.7 0.2 0.00017 21.7 0.1 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat SelK_SelG PF10961.8 EPS27798.1 - 0.1 13.2 2.6 0.28 11.8 2.6 1.7 1 0 0 1 1 1 0 Selenoprotein SelK_SelG ERG4_ERG24 PF01222.17 EPS27799.1 - 3.2e-159 530.3 5.4 3.7e-159 530.1 5.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EPS27799.1 - 4.1e-05 23.2 0.3 0.00012 21.7 0.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Ferlin_C PF16165.5 EPS27799.1 - 2.6 8.0 4.0 0.82 9.6 0.5 2.0 2 0 0 2 2 2 0 Ferlin C-terminus A_deamin PF02137.18 EPS27800.1 - 3.1e-20 72.9 0.1 1.4e-08 34.6 0.0 3.3 3 1 0 3 3 3 3 Adenosine-deaminase (editase) domain SF3b10 PF07189.11 EPS27801.1 - 5.7e-35 119.3 0.0 6.4e-35 119.1 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) DUF3074 PF11274.8 EPS27802.1 - 3.3e-55 186.9 0.0 6.7e-55 185.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) START PF01852.19 EPS27802.1 - 0.0088 15.5 0.0 0.43 10.0 0.0 2.4 2 0 0 2 2 2 1 START domain AAA_23 PF13476.6 EPS27802.1 - 0.028 14.9 9.4 3.4 8.1 9.5 2.4 2 0 0 2 2 2 0 AAA domain APG6_N PF17675.1 EPS27802.1 - 0.86 10.1 29.0 1.4 9.5 8.2 3.4 2 1 1 3 3 3 0 Apg6 coiled-coil region TSC22 PF01166.18 EPS27802.1 - 1.1 9.6 5.3 1 9.7 1.9 2.7 3 0 0 3 3 3 0 TSC-22/dip/bun family SOGA PF11365.8 EPS27802.1 - 4.1 8.6 13.4 15 6.8 10.3 2.6 2 0 0 2 2 2 0 Protein SOGA FapA PF03961.13 EPS27802.1 - 6.2 5.3 14.8 0.96 8.0 10.2 1.8 2 0 0 2 2 2 0 Flagellar Assembly Protein A Seryl_tRNA_N PF02403.22 EPS27802.1 - 6.7 7.0 20.2 4.3 7.6 12.6 2.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Allexi_40kDa PF05549.11 EPS27802.1 - 7.1 6.1 11.4 12 5.3 4.4 2.6 3 0 0 3 3 3 0 Allexivirus 40kDa protein FAM76 PF16046.5 EPS27802.1 - 8.9 5.6 15.7 18 4.6 15.7 1.5 1 0 0 1 1 1 0 FAM76 protein DUF4337 PF14235.6 EPS27802.1 - 9.3 6.3 9.4 21 5.2 6.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) bZIP_Maf PF03131.17 EPS27802.1 - 9.9 6.8 16.0 0.69 10.5 10.4 2.0 2 0 0 2 2 2 0 bZIP Maf transcription factor Caprin-1_dimer PF18293.1 EPS27803.1 - 0.099 13.1 0.1 0.17 12.4 0.1 1.4 1 0 0 1 1 1 0 Caprin-1 dimerization domain GST_N_3 PF13417.6 EPS27805.1 - 6.8e-09 36.0 0.0 2e-08 34.5 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EPS27805.1 - 9.9e-07 28.7 0.2 2e-06 27.8 0.2 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EPS27805.1 - 2e-06 28.0 0.1 5.5e-06 26.6 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_4 PF14834.6 EPS27805.1 - 0.028 14.8 0.1 0.046 14.1 0.1 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Mgr1 PF08602.10 EPS27807.1 - 0.0052 15.7 0.3 0.0062 15.4 0.3 1.0 1 0 0 1 1 1 1 Mgr1-like, i-AAA protease complex subunit Spc7 PF08317.11 EPS27807.1 - 0.0093 14.9 4.1 0.011 14.6 4.1 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein DivIVA PF05103.13 EPS27807.1 - 0.021 14.9 5.1 0.026 14.6 5.1 1.2 1 0 0 1 1 1 0 DivIVA protein She9_MDM33 PF05546.11 EPS27807.1 - 0.13 12.0 4.1 0.17 11.7 4.1 1.1 1 0 0 1 1 1 0 She9 / Mdm33 family DUF4407 PF14362.6 EPS27807.1 - 0.17 11.2 5.6 0.2 11.0 5.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Band_7 PF01145.25 EPS27807.1 - 0.21 11.6 4.2 0.44 10.5 4.3 1.3 1 1 0 1 1 1 0 SPFH domain / Band 7 family NT-C2 PF10358.9 EPS27808.1 - 3.9e-36 124.0 0.2 5.2e-36 123.6 0.2 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Sld3_N PF18523.1 EPS27808.1 - 0.049 13.8 1.0 6.1 7.0 0.2 2.4 1 1 1 2 2 2 0 Sld3 N-terminal domain Myotub-related PF06602.14 EPS27809.1 - 2.9e-152 506.7 0.0 3.5e-152 506.4 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.20 EPS27809.1 - 0.037 13.9 0.0 0.097 12.6 0.0 1.6 1 0 0 1 1 1 0 GRAM domain Ribosomal_S3_C PF00189.20 EPS27810.1 - 1e-24 86.9 0.2 5e-24 84.6 0.2 2.0 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 EPS27810.1 - 6.8e-12 45.1 0.1 1.2e-11 44.3 0.1 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.8 EPS27810.1 - 0.097 13.2 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Coilin_N PF15862.5 EPS27810.1 - 0.14 12.0 0.1 0.33 10.7 0.0 1.6 2 0 0 2 2 2 0 Coilin N-terminus tRNA_synthFbeta PF17759.1 EPS27811.1 - 1.3e-48 165.3 0.0 1.8e-48 164.8 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 EPS27811.1 - 1.3e-33 115.1 0.1 4.3e-32 110.2 0.1 2.5 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 EPS27811.1 - 2.1e-25 89.4 0.0 4e-25 88.5 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 EPS27811.1 - 8.5e-19 67.6 0.0 2.5e-16 59.7 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetase B5 domain HEAT PF02985.22 EPS27812.1 - 1.3e-35 118.4 18.9 0.015 15.5 0.1 13.5 14 0 0 14 14 13 10 HEAT repeat HEAT_2 PF13646.6 EPS27812.1 - 2.4e-35 120.8 4.9 1.3e-10 41.5 0.0 8.1 3 3 5 8 8 8 8 HEAT repeats HEAT_EZ PF13513.6 EPS27812.1 - 6.9e-15 55.2 5.7 0.025 15.1 0.0 8.8 7 2 2 9 9 9 3 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EPS27812.1 - 1.6e-11 44.7 4.6 0.0015 19.1 0.1 7.4 5 2 5 10 10 10 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EPS27812.1 - 4.1e-09 36.7 11.2 0.0031 17.6 0.1 5.8 5 2 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EPS27812.1 - 8.6e-08 31.2 10.2 2e-06 26.7 2.5 4.4 3 1 1 4 4 4 3 Adaptin N terminal region RTP1_C1 PF10363.9 EPS27812.1 - 1.3e-05 25.3 5.6 1.7 8.9 0.1 5.0 3 1 1 4 4 4 3 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 EPS27812.1 - 0.0038 16.8 1.8 0.33 10.5 0.2 3.9 3 2 1 4 4 4 1 CLASP N terminal TetR_C_16 PF17920.1 EPS27812.1 - 0.058 13.6 1.3 27 5.1 0.0 3.7 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Proteasom_PSMB PF10508.9 EPS27812.1 - 0.12 10.8 4.1 0.71 8.3 0.0 2.6 2 1 0 3 3 3 0 Proteasome non-ATPase 26S subunit Arm PF00514.23 EPS27812.1 - 0.15 12.1 6.9 3.7 7.7 0.0 5.5 8 0 0 8 8 7 0 Armadillo/beta-catenin-like repeat API5 PF05918.11 EPS27812.1 - 0.42 9.4 4.0 0.35 9.6 0.1 3.0 3 1 1 4 4 4 0 Apoptosis inhibitory protein 5 (API5) IFRD PF05004.13 EPS27812.1 - 0.44 9.6 3.1 1.3 8.1 0.2 3.1 3 1 1 4 4 4 0 Interferon-related developmental regulator (IFRD) Ferric_reduct PF01794.19 EPS27813.1 - 3.6e-11 43.3 3.6 3.6e-11 43.3 3.6 2.5 2 2 0 2 2 2 1 Ferric reductase like transmembrane component DUF2644 PF10841.8 EPS27813.1 - 0.029 14.6 0.7 2.9 8.2 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2644) Glyco_transf_90 PF05686.12 EPS27814.1 - 3.7e-18 65.6 8.9 1.2e-14 54.0 7.7 2.9 2 1 0 2 2 2 2 Glycosyl transferase family 90 Abhydrolase_1 PF00561.20 EPS27815.1 - 1.6e-14 54.2 0.6 1.1e-09 38.4 0.1 2.7 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPS27815.1 - 2.3e-14 54.6 5.6 6.3e-13 49.8 5.6 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPS27815.1 - 0.00033 20.0 0.1 0.00086 18.6 0.0 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF900 PF05990.12 EPS27815.1 - 0.0052 16.3 0.0 0.094 12.2 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) EHN PF06441.12 EPS27815.1 - 0.0085 16.4 0.1 0.018 15.4 0.1 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Ser_hydrolase PF06821.13 EPS27815.1 - 0.028 14.3 0.1 0.26 11.1 0.0 2.3 2 0 0 2 2 2 0 Serine hydrolase Glyco_transf_8 PF01501.20 EPS27816.1 - 1e-22 80.9 0.1 5.5e-22 78.5 0.1 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.16 EPS27816.1 - 0.0035 17.4 0.0 0.0059 16.6 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase APH PF01636.23 EPS27818.1 - 3.2e-09 37.1 0.1 8.1e-09 35.8 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPS27818.1 - 0.0023 17.6 0.0 0.0029 17.2 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase Aa_trans PF01490.18 EPS27819.1 - 2.2e-41 141.9 29.1 2.8e-41 141.6 29.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CAAD PF14159.6 EPS27819.1 - 0.47 10.3 5.0 5.4 6.9 0.1 3.2 3 0 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF1201 PF06716.11 EPS27819.1 - 5.2 7.2 14.2 0.24 11.4 0.6 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1201) MMR_HSR1_Xtn PF16897.5 EPS27820.1 - 2.4e-40 136.8 1.0 7.9e-40 135.2 0.5 2.0 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 EPS27820.1 - 8.2e-22 77.0 0.1 2e-21 75.8 0.1 1.7 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 EPS27820.1 - 1.1e-20 73.8 0.1 3.1e-20 72.3 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EPS27820.1 - 4.8e-10 39.2 0.1 3.4e-09 36.4 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 EPS27820.1 - 0.00028 20.5 0.2 2.9 7.4 0.0 3.9 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EPS27820.1 - 0.00057 20.0 0.2 0.13 12.3 0.0 2.5 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 EPS27820.1 - 0.0036 16.3 0.1 0.018 14.0 0.1 2.0 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 EPS27820.1 - 0.028 13.9 0.4 2.4 7.6 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EPS27820.1 - 0.084 12.8 2.1 3.9 7.4 0.0 3.2 3 1 1 4 4 4 0 RsgA GTPase HTH_Tnp_Tc5 PF03221.16 EPS27821.1 - 3e-15 56.0 0.0 6e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.13 EPS27821.1 - 2e-05 24.1 0.1 4.3e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.6 EPS27821.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain MarR PF01047.22 EPS27821.1 - 0.036 14.0 0.0 0.14 12.1 0.0 2.1 1 0 0 1 1 1 0 MarR family HTH_Tnp_4 PF13613.6 EPS27821.1 - 0.036 13.8 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_23 PF13384.6 EPS27821.1 - 0.039 13.8 0.1 0.17 11.7 0.0 2.1 2 0 0 2 2 2 0 Homeodomain-like domain HTH_10 PF04967.12 EPS27821.1 - 0.074 12.9 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain HTH_Crp_2 PF13545.6 EPS27821.1 - 0.13 12.2 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain PXA PF02194.15 EPS27823.1 - 4e-45 154.0 0.0 5.4e-45 153.6 0.0 1.2 1 0 0 1 1 1 1 PXA domain Tecti-min-caps PF09300.10 EPS27823.1 - 0.067 13.2 0.7 11 6.2 0.0 2.4 2 0 0 2 2 2 0 Tectiviridae, minor capsid PUL PF08324.11 EPS27823.1 - 0.1 11.9 0.0 0.21 10.8 0.0 1.4 1 0 0 1 1 1 0 PUL domain IU_nuc_hydro PF01156.19 EPS27824.1 - 3.9e-74 250.0 0.0 4.4e-74 249.8 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Vac_ImportDeg PF09783.9 EPS27825.1 - 8.6e-39 132.9 0.0 1.6e-38 132.1 0.0 1.4 1 0 0 1 1 1 1 Vacuolar import and degradation protein MFS_1 PF07690.16 EPS27826.1 - 2.2e-21 76.2 60.5 1.2e-15 57.3 33.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EPS27826.1 - 6.1e-05 21.8 33.8 7.7e-05 21.4 11.8 2.5 3 0 0 3 3 3 2 MFS/sugar transport protein Trp_syntA PF00290.20 EPS27827.1 - 6e-96 320.3 0.0 5.2e-95 317.2 0.0 2.0 2 0 0 2 2 2 1 Tryptophan synthase alpha chain PALP PF00291.25 EPS27827.1 - 1.1e-42 146.5 0.3 1.7e-42 145.8 0.3 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Fungal_trans PF04082.18 EPS27828.1 - 5.7e-15 55.1 2.2 2.7e-14 52.9 0.1 2.7 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS27828.1 - 6.7e-06 26.1 10.4 1.2e-05 25.3 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4834 PF16118.5 EPS27828.1 - 0.0039 18.1 0.5 0.01 16.8 0.5 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) DUF2722 PF10846.8 EPS27828.1 - 0.0065 15.5 20.4 0.011 14.8 20.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Peptidase_S49_N PF08496.10 EPS27828.1 - 0.036 14.1 3.5 0.08 13.0 3.5 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal eIF-3_zeta PF05091.12 EPS27828.1 - 0.057 12.4 4.6 0.08 11.9 4.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.17 EPS27828.1 - 0.068 11.9 3.0 0.1 11.3 3.0 1.3 1 0 0 1 1 1 0 Presenilin TERB2 PF15101.6 EPS27828.1 - 0.12 12.4 5.8 0.27 11.3 5.8 1.6 1 0 0 1 1 1 0 Telomere-associated protein TERB2 CAML PF14963.6 EPS27828.1 - 0.14 12.3 2.4 0.29 11.2 2.4 1.4 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Spt20 PF12090.8 EPS27828.1 - 0.18 11.4 27.7 0.088 12.4 25.4 1.5 2 0 0 2 2 2 0 Spt20 family Med3 PF11593.8 EPS27828.1 - 0.22 10.7 11.1 0.49 9.5 11.1 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TFIIA PF03153.13 EPS27828.1 - 0.39 10.6 20.9 0.65 9.9 20.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EPL1 PF10513.9 EPS27828.1 - 0.61 10.5 7.1 1.6 9.1 7.1 1.7 1 0 0 1 1 1 0 Enhancer of polycomb-like CPSF100_C PF13299.6 EPS27828.1 - 0.69 10.1 5.6 0.53 10.4 3.6 1.7 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal V_ATPase_I PF01496.19 EPS27828.1 - 1.8 6.4 7.4 2.8 5.8 7.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FAM176 PF14851.6 EPS27828.1 - 1.9 8.2 6.9 20 4.8 0.0 2.4 2 0 0 2 2 2 0 FAM176 family Roughex PF06020.11 EPS27828.1 - 2.8 7.0 13.2 4.5 6.3 13.2 1.2 1 0 0 1 1 1 0 Drosophila roughex protein CobT PF06213.12 EPS27828.1 - 4.4 6.6 13.8 9 5.6 13.8 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Orf78 PF06024.12 EPS27828.1 - 5.2 7.4 7.2 25 5.2 3.7 2.4 2 0 0 2 2 2 0 Orf78 (ac78) Baculo_PP31 PF05311.11 EPS27828.1 - 9 5.7 10.3 15 4.9 10.3 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Zn_clus PF00172.18 EPS27829.1 - 1.7e-11 44.0 9.8 2.8e-11 43.3 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPS27829.1 - 0.00033 19.8 0.3 0.00046 19.3 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Papo_T_antigen PF02380.15 EPS27829.1 - 6.1 7.1 6.1 17 5.7 0.1 3.1 3 0 0 3 3 3 0 T-antigen specific domain NMO PF03060.15 EPS27830.1 - 7.4e-36 124.2 8.3 1.4e-34 120.0 8.3 2.3 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EPS27830.1 - 1.8e-10 40.4 0.7 4e-09 35.9 0.7 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EPS27830.1 - 1.5e-06 27.5 2.6 2.9e-06 26.6 2.6 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 EPS27830.1 - 0.00011 21.5 0.1 0.00017 20.8 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Ribosomal_L7Ae PF01248.26 EPS27831.1 - 1.7e-26 91.8 0.6 2.1e-26 91.5 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 EPS27831.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain Ank_2 PF12796.7 EPS27832.1 - 6.8e-20 71.4 0.0 3.9e-11 43.4 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EPS27832.1 - 6.9e-16 58.1 0.7 1.1e-06 28.7 0.0 4.6 2 2 3 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EPS27832.1 - 1.1e-14 54.6 0.0 3.8e-09 36.9 0.0 4.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EPS27832.1 - 2.7e-11 43.4 0.0 0.0011 19.3 0.0 4.3 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 EPS27832.1 - 4.1e-10 39.0 0.0 0.013 15.9 0.0 4.7 5 0 0 5 5 5 2 Ankyrin repeat Steroid_dh PF02544.16 EPS27834.1 - 1.5e-12 47.7 0.9 1.5e-12 47.7 0.9 1.7 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase FAP PF07174.11 EPS27834.1 - 0.13 11.7 7.0 0.18 11.2 7.0 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) 2OG-FeII_Oxy_2 PF13532.6 EPS27835.1 - 9.7e-15 55.3 0.0 7.6e-13 49.1 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Rotamase_3 PF13616.6 EPS27836.1 - 6.6e-18 65.3 0.0 1.3e-17 64.4 0.0 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 EPS27836.1 - 4.4e-16 59.6 0.0 6.7e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 EPS27836.1 - 7.2e-06 26.8 0.1 1e-05 26.3 0.0 1.3 1 1 0 1 1 1 1 PPIC-type PPIASE domain UAA PF08449.11 EPS27837.1 - 2.8e-44 151.5 10.6 4.6e-44 150.8 10.6 1.3 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 EPS27837.1 - 4.4e-08 33.4 27.1 1.2e-06 28.7 4.9 3.4 3 0 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.15 EPS27837.1 - 1.7e-07 30.7 2.3 0.0018 17.5 0.5 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter DUF5090 PF17009.5 EPS27837.1 - 7.6 6.5 6.1 8.6 6.3 1.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF5090) Sen15 PF09631.10 EPS27838.1 - 1.7e-14 53.9 0.0 1.7e-13 50.7 0.0 2.0 1 1 0 1 1 1 1 Sen15 protein Inhibitor_I66 PF16850.5 EPS27838.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Peptidase inhibitor I66 VASt PF16016.5 EPS27839.1 - 4e-34 118.2 0.1 1.1e-33 116.8 0.1 1.8 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain BAR_3 PF16746.5 EPS27839.1 - 3.8e-14 53.0 1.2 6e-14 52.3 0.2 1.9 2 0 0 2 2 2 1 BAR domain of APPL family PH PF00169.29 EPS27839.1 - 8.6e-09 35.9 0.0 2.6e-08 34.3 0.0 1.9 1 0 0 1 1 1 1 PH domain BAR PF03114.18 EPS27839.1 - 0.0073 16.0 0.8 0.017 14.8 0.8 1.6 1 0 0 1 1 1 1 BAR domain GRAM PF02893.20 EPS27839.1 - 0.065 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 GRAM domain PH_13 PF16652.5 EPS27839.1 - 0.11 12.3 0.0 0.35 10.7 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain Kri1_C PF12936.7 EPS27840.1 - 3.5e-33 113.6 0.4 3.5e-33 113.6 0.4 3.9 3 1 1 4 4 4 1 KRI1-like family C-terminal Kri1 PF05178.12 EPS27840.1 - 1.9e-29 102.2 19.6 1.9e-29 102.2 19.6 5.4 4 2 1 5 5 5 1 KRI1-like family Spem1 PF15670.5 EPS27840.1 - 0.3 10.6 3.4 0.94 9.0 3.4 1.8 1 0 0 1 1 1 0 Spermatid maturation protein 1 CPP1-like PF11833.8 EPS27840.1 - 5.2 6.7 6.5 11 5.6 6.5 1.5 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Mig-14 PF07395.11 EPS27840.1 - 7.2 5.9 9.2 0.21 10.9 0.3 2.2 2 0 0 2 2 2 0 Mig-14 Mito_carr PF00153.27 EPS27841.1 - 3.3e-68 225.7 6.2 2.1e-24 85.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Stb3 PF10330.9 EPS27844.1 - 3.2e-38 129.6 0.0 5.5e-38 128.9 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein Auxin_repressed PF05564.12 EPS27844.1 - 0.12 13.1 0.8 0.23 12.1 0.8 1.5 1 0 0 1 1 1 0 Dormancy/auxin associated protein COesterase PF00135.28 EPS27845.1 - 1.7e-80 271.4 0.0 4.8e-80 269.9 0.0 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EPS27845.1 - 4.3e-10 39.8 0.3 2.6e-09 37.3 0.3 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EPS27845.1 - 0.001 18.6 0.2 0.0017 17.9 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family fn3_PAP PF17808.1 EPS27845.1 - 0.13 12.4 0.1 1.2 9.3 0.0 2.1 2 0 0 2 2 2 0 Fn3-like domain from Purple Acid Phosphatase Helo_like_N PF17111.5 EPS27846.1 - 2.5e-06 27.0 2.4 4.6e-06 26.2 2.1 1.6 1 1 1 2 2 2 1 Fungal N-terminal domain of STAND proteins SesA PF17107.5 EPS27846.1 - 5.7e-06 26.5 0.1 1.9e-05 24.8 0.1 1.8 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases CoA_transf_3 PF02515.17 EPS27847.1 - 2e-41 142.3 0.2 1.1e-38 133.3 0.1 2.2 2 0 0 2 2 2 2 CoA-transferase family III SnoaL_2 PF12680.7 EPS27848.1 - 0.029 15.0 0.0 0.04 14.6 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain Ribosomal_S19e PF01090.19 EPS27849.1 - 8.2e-58 194.0 0.2 9.2e-58 193.8 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Abhydrolase_1 PF00561.20 EPS27850.1 - 1.3e-17 64.4 0.0 3.6e-16 59.6 0.0 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPS27850.1 - 1.3e-15 58.6 0.6 3.9e-15 57.1 0.6 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPS27850.1 - 3.4e-11 42.9 0.0 2.1e-07 30.5 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DSPc PF00782.20 EPS27850.1 - 2.4e-10 40.3 0.0 4.5e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Thioesterase PF00975.20 EPS27850.1 - 7.4e-05 23.0 0.1 0.00014 22.1 0.1 1.4 1 0 0 1 1 1 1 Thioesterase domain FSH1 PF03959.13 EPS27850.1 - 0.00022 21.0 0.0 0.0026 17.5 0.0 2.2 1 1 0 1 1 1 1 Serine hydrolase (FSH1) PGAP1 PF07819.13 EPS27850.1 - 0.0012 18.6 0.2 0.037 13.8 0.2 2.5 1 1 0 1 1 1 1 PGAP1-like protein Ser_hydrolase PF06821.13 EPS27850.1 - 0.0028 17.6 0.0 0.035 14.0 0.0 2.5 2 0 0 2 2 2 1 Serine hydrolase PTPlike_phytase PF14566.6 EPS27850.1 - 0.014 15.5 0.0 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase PF00102.27 EPS27850.1 - 0.043 13.4 0.0 0.11 12.1 0.0 1.6 2 0 0 2 2 2 0 Protein-tyrosine phosphatase DUF1749 PF08538.10 EPS27850.1 - 0.052 12.6 0.0 1.7 7.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Lipase_3 PF01764.25 EPS27850.1 - 0.056 13.3 1.0 0.11 12.3 0.3 1.8 1 1 1 2 2 2 0 Lipase (class 3) Chlorophyllase2 PF12740.7 EPS27850.1 - 0.11 11.3 0.1 0.34 9.8 0.0 1.7 2 1 0 2 2 2 0 Chlorophyllase enzyme Abhydrolase_4 PF08386.10 EPS27850.1 - 0.15 12.2 0.0 0.32 11.1 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein LIDHydrolase PF10230.9 EPS27850.1 - 0.19 11.3 0.0 0.31 10.5 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase ILVD_EDD PF00920.21 EPS27851.1 - 1.3e-212 707.0 0.1 1.6e-212 706.8 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family Pex2_Pex12 PF04757.14 EPS27852.1 - 3.1e-36 125.1 0.6 4.5e-36 124.5 0.6 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 EPS27852.1 - 0.0016 18.5 5.1 0.0032 17.6 5.1 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EPS27852.1 - 0.017 15.2 0.8 0.049 13.7 0.8 1.8 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EPS27852.1 - 0.075 12.9 2.5 0.088 12.7 0.4 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPS27852.1 - 0.16 11.8 1.8 0.38 10.7 1.8 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Phosphoesterase PF04185.14 EPS27853.1 - 3.2e-33 115.4 6.9 2e-32 112.7 6.9 2.1 1 1 0 1 1 1 1 Phosphoesterase family HIF-1a_CTAD PF08778.10 EPS27853.1 - 0.074 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 HIF-1 alpha C terminal transactivation domain IBN_N PF03810.19 EPS27855.1 - 8.2e-13 48.1 0.0 5.8e-12 45.4 0.0 2.6 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EPS27855.1 - 0.0054 16.8 1.2 0.028 14.5 0.1 2.8 3 0 0 3 3 3 1 Exportin 1-like protein Cellulase PF00150.18 EPS27856.1 - 1.4e-15 57.5 1.7 1.4e-15 57.5 1.7 2.2 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) DUF3922 PF13059.6 EPS27856.1 - 0.14 12.6 0.0 0.26 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3992) Glyco_hydro_2_N PF02837.18 EPS27857.1 - 9.3e-16 58.2 0.0 4.3e-15 56.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 EPS27857.1 - 3.4e-11 43.8 2.1 4.9e-11 43.3 0.1 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.17 EPS27857.1 - 3.7e-10 39.4 0.0 7e-09 35.2 0.0 2.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain BetaGal_dom4_5 PF13364.6 EPS27857.1 - 0.086 13.4 0.2 0.25 11.9 0.2 1.8 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain Protoglobin PF11563.8 EPS27858.1 - 1.8e-55 187.2 0.1 2.2e-55 186.9 0.1 1.1 1 0 0 1 1 1 1 Protoglobin Aldedh PF00171.22 EPS27859.1 - 2.1e-136 455.1 0.5 2.5e-136 454.8 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EPS27859.1 - 8.2e-05 21.8 0.1 0.00027 20.1 0.1 1.6 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) GPI-anchored PF10342.9 EPS27861.1 - 2.2e-21 76.4 0.0 2.2e-21 76.4 0.0 2.7 2 1 0 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF2462 PF09495.10 EPS27862.1 - 9.5e-23 80.7 12.9 9.5e-23 80.7 12.9 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2462) Zn_clus PF00172.18 EPS27863.1 - 0.0071 16.4 10.8 0.016 15.3 10.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BAALC_N PF06989.12 EPS27863.1 - 0.054 13.8 3.7 13 6.2 0.1 3.9 3 0 0 3 3 3 0 BAALC N-terminus SurE PF01975.17 EPS27864.1 - 4.4e-51 173.5 0.0 7e-51 172.8 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE DUF5427 PF10310.9 EPS27865.1 - 4.2e-169 563.4 0.0 4.8e-169 563.2 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5427) TSP9 PF11493.8 EPS27865.1 - 0.059 14.0 0.8 0.26 12.0 0.1 2.6 2 0 0 2 2 2 0 Thylakoid soluble phosphoprotein TSP9 SARAF PF06682.12 EPS27865.1 - 0.66 9.6 5.9 1.1 8.8 5.9 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Ndc1_Nup PF09531.10 EPS27865.1 - 5 5.7 4.1 2.3 6.8 1.8 1.5 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup CMD PF02627.20 EPS27867.1 - 4e-07 30.0 0.2 1.2e-05 25.2 0.1 2.5 2 1 0 2 2 2 2 Carboxymuconolactone decarboxylase family DBINO PF13892.6 EPS27868.1 - 0.28 11.6 8.7 0.071 13.5 5.3 1.7 2 0 0 2 2 2 0 DNA-binding domain zf-C2H2_4 PF13894.6 EPS27869.1 - 0.00018 22.0 5.3 0.061 14.2 1.0 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EPS27869.1 - 0.012 16.1 6.2 0.048 14.1 0.9 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type Endomucin PF07010.12 EPS27869.1 - 0.042 13.8 2.4 0.075 13.0 2.4 1.3 1 0 0 1 1 1 0 Endomucin Ima1_N PF09779.9 EPS27869.1 - 0.24 12.3 3.3 0.91 10.4 0.1 2.3 2 0 0 2 2 2 0 Ima1 N-terminal domain Tmemb_14 PF03647.13 EPS27871.1 - 3.8e-20 72.4 10.5 5.1e-20 72.0 10.5 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C MFS_1 PF07690.16 EPS27872.1 - 7.5e-37 127.1 35.0 1.7e-32 112.8 16.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS27872.1 - 4.3e-11 42.3 6.7 1.1e-09 37.7 3.0 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_3 PF05977.13 EPS27872.1 - 0.0044 15.5 3.9 0.0044 15.5 3.9 2.1 2 0 0 2 2 2 1 Transmembrane secretion effector DUF5359 PF17313.2 EPS27872.1 - 0.019 14.9 0.1 0.056 13.4 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5359) MotA_ExbB PF01618.16 EPS27872.1 - 0.24 11.2 2.2 2.5 7.9 0.1 2.5 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family TFR_dimer PF04253.15 EPS27873.1 - 1.8e-30 105.5 0.0 3.2e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EPS27873.1 - 2.2e-21 76.5 0.0 3.5e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EPS27873.1 - 5.6e-09 35.9 0.0 1.4e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.15 EPS27873.1 - 0.039 13.4 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 Nicastrin RTC4 PF14474.6 EPS27874.1 - 5.5e-32 110.5 0.2 1.7e-31 108.9 0.0 1.9 2 0 0 2 2 2 1 RTC4-like domain DUF726 PF05277.12 EPS27875.1 - 1.2e-126 422.3 2.7 1.6e-126 421.9 2.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Fungal_trans PF04082.18 EPS27877.1 - 4.6e-05 22.6 0.0 8.4e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS27877.1 - 0.00011 22.2 12.5 0.00018 21.6 12.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4545 PF15078.6 EPS27877.1 - 0.27 10.2 2.1 0.41 9.6 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4545) p450 PF00067.22 EPS27880.1 - 2.7e-42 145.1 0.0 3.3e-42 144.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 LicD PF04991.13 EPS27882.1 - 2.2e-21 77.0 7.2 2.3e-15 57.3 3.5 2.2 1 1 1 2 2 2 2 LicD family Fungal_trans PF04082.18 EPS27883.1 - 1.2e-16 60.6 0.0 2.6e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS27883.1 - 3e-10 40.0 10.4 5.9e-10 39.1 10.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Apis_Csd PF11671.8 EPS27883.1 - 2.3 8.2 5.8 4.9 7.2 5.8 1.4 1 0 0 1 1 1 0 Complementary sex determiner protein Senescence PF06911.12 EPS27884.1 - 0.017 15.5 6.2 0.023 15.0 6.2 1.2 1 0 0 1 1 1 0 Senescence-associated protein VPS13_C PF16909.5 EPS27884.1 - 0.55 10.0 3.5 0.54 10.0 2.5 1.5 1 1 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal DAD PF02109.16 EPS27885.1 - 4.1e-47 159.0 0.2 5.4e-47 158.6 0.2 1.1 1 0 0 1 1 1 1 DAD family HA2 PF04408.23 EPS27886.1 - 1.6e-19 70.2 1.0 7.8e-19 68.0 0.0 2.6 3 0 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EPS27886.1 - 2.8e-16 59.6 0.0 6e-15 55.4 0.0 2.5 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EPS27886.1 - 2e-15 57.1 0.0 5.2e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EPS27886.1 - 9e-06 25.6 1.3 2e-05 24.4 0.3 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EPS27886.1 - 2.4e-05 24.6 0.6 5.7e-05 23.4 0.1 1.9 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 EPS27886.1 - 0.0005 19.8 1.4 0.00084 19.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EPS27886.1 - 0.0016 18.8 0.1 0.0046 17.3 0.1 1.7 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 EPS27886.1 - 0.0026 17.8 0.1 0.0051 16.8 0.1 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain DUF2075 PF09848.9 EPS27886.1 - 0.0027 17.0 0.0 0.0052 16.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 EPS27886.1 - 0.0052 15.9 0.0 0.017 14.2 0.0 1.9 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.22 EPS27886.1 - 0.0067 16.1 0.3 0.021 14.5 0.3 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.15 EPS27886.1 - 0.026 14.5 0.0 5.9 6.9 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_14 PF13173.6 EPS27886.1 - 0.03 14.4 0.1 0.22 11.6 0.1 2.3 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 EPS27886.1 - 0.05 12.9 0.0 0.097 12.0 0.0 1.4 1 0 0 1 1 1 0 KaiC cobW PF02492.19 EPS27886.1 - 0.052 13.1 0.2 0.41 10.2 0.0 2.4 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.27 EPS27886.1 - 0.07 13.6 1.2 0.82 10.2 0.2 3.0 2 1 0 2 2 2 0 ABC transporter AAA_16 PF13191.6 EPS27886.1 - 0.075 13.4 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 EPS27886.1 - 0.077 13.2 0.7 0.48 10.6 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EPS27886.1 - 0.077 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 EPS27886.1 - 0.094 13.2 2.4 0.38 11.2 0.0 3.0 4 1 0 4 4 4 0 AAA domain LYRIC PF15686.5 EPS27886.1 - 1.8 8.1 6.2 0.12 11.9 1.2 1.5 2 0 0 2 2 2 0 Lysine-rich CEACAM1 co-isolated protein family Prefoldin_2 PF01920.20 EPS27887.1 - 1.7e-24 85.8 7.4 2.2e-24 85.5 7.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit ATF7IP_BD PF16788.5 EPS27887.1 - 0.033 14.3 2.4 0.039 14.1 2.4 1.1 1 0 0 1 1 1 0 ATF-interacting protein binding domain DASH_Dad3 PF08656.10 EPS27887.1 - 0.04 14.0 1.9 0.23 11.5 0.1 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad3 ATP-synt_D PF01813.17 EPS27887.1 - 0.095 12.5 2.1 2.8 7.7 0.2 2.0 2 0 0 2 2 2 0 ATP synthase subunit D Prefoldin PF02996.17 EPS27887.1 - 0.099 12.6 6.6 0.8 9.6 0.1 2.1 1 1 0 2 2 2 0 Prefoldin subunit Wtap PF17098.5 EPS27887.1 - 0.12 12.3 3.8 0.39 10.6 3.8 1.7 1 1 0 1 1 1 0 WTAP/Mum2p family Occludin_ELL PF07303.13 EPS27887.1 - 0.19 12.5 4.0 15 6.4 4.0 2.1 1 1 0 1 1 1 0 Occludin homology domain FliE PF02049.18 EPS27887.1 - 0.23 11.6 4.1 3.9 7.7 0.8 2.1 2 0 0 2 2 2 0 Flagellar hook-basal body complex protein FliE DUF2205 PF10224.9 EPS27887.1 - 0.41 10.7 6.7 0.095 12.7 2.5 1.9 2 0 0 2 2 2 0 Short coiled-coil protein ZnuA PF01297.17 EPS27887.1 - 0.45 9.9 3.0 1.4 8.3 0.5 2.0 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic OmpH PF03938.14 EPS27887.1 - 2.4 8.5 11.5 9.2 6.6 5.0 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) CBFD_NFYB_HMF PF00808.23 EPS27888.1 - 2.8e-29 101.2 1.0 3.8e-29 100.8 1.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EPS27888.1 - 3.8e-06 27.3 0.0 6.1e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 EPS27888.1 - 0.00086 19.3 0.0 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.13 EPS27888.1 - 0.0016 18.4 0.1 0.0027 17.7 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated CENP-T_C PF15511.6 EPS27888.1 - 0.0048 17.0 0.0 0.0067 16.5 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID_20kDa PF03847.13 EPS27888.1 - 0.052 14.0 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A ATP-synt_ab_C PF00306.27 EPS27888.1 - 0.22 11.9 1.9 1.3 9.3 0.2 2.0 2 0 0 2 2 2 0 ATP synthase alpha/beta chain, C terminal domain Fungal_trans PF04082.18 EPS27889.1 - 3.2e-19 69.0 0.1 2.8e-18 65.9 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS27889.1 - 3.2e-09 36.8 11.1 4.8e-09 36.2 11.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CAP_N PF01213.19 EPS27889.1 - 0.077 12.5 7.5 0.14 11.7 7.5 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TatD_DNase PF01026.21 EPS27890.1 - 9.5e-36 123.5 0.0 2e-35 122.4 0.0 1.4 1 1 0 1 1 1 1 TatD related DNase Draxin PF15550.6 EPS27890.1 - 0.14 12.0 2.3 0.07 13.0 0.4 1.4 2 0 0 2 2 2 0 Draxin PRP1_N PF06424.12 EPS27891.1 - 0.2 12.0 0.8 10 6.5 0.1 2.4 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Abhydrolase_1 PF00561.20 EPS27892.1 - 1.9e-19 70.3 0.0 1.2e-17 64.4 0.0 2.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EPS27892.1 - 5.2e-15 55.4 0.0 8.9e-14 51.3 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EPS27892.1 - 1.3e-11 45.5 15.0 4.9e-10 40.4 11.7 2.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.11 EPS27892.1 - 0.00012 21.5 0.0 0.00023 20.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 EPS27892.1 - 0.00016 21.5 0.0 0.00035 20.3 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 EPS27892.1 - 0.0088 15.0 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_2 PF02230.16 EPS27892.1 - 0.012 15.4 0.1 0.32 10.8 0.0 2.8 3 1 0 3 3 3 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 EPS27892.1 - 0.089 12.6 0.0 0.3 10.9 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold LIDHydrolase PF10230.9 EPS27892.1 - 0.13 11.8 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Thioesterase PF00975.20 EPS27892.1 - 0.14 12.2 0.4 0.53 10.4 0.5 1.9 1 1 0 1 1 1 0 Thioesterase domain Abhydrolase_5 PF12695.7 EPS27892.1 - 0.15 11.8 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Chlorophyllase PF07224.11 EPS27892.1 - 0.16 10.9 0.0 0.25 10.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Lipase_3 PF01764.25 EPS27892.1 - 0.19 11.6 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Spo7 PF03907.13 EPS27893.1 - 1.2e-91 306.1 0.1 1.8e-91 305.5 0.1 1.2 1 0 0 1 1 1 1 Spo7-like protein Cupin_2 PF07883.11 EPS27894.1 - 5.4e-21 74.1 0.3 2.5e-10 39.9 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 EPS27894.1 - 1e-16 60.4 1.3 2.9e-13 49.3 0.2 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) CENP-C_C PF11699.8 EPS27894.1 - 0.00011 22.4 0.0 0.00031 20.9 0.0 1.7 2 0 0 2 2 2 1 Mif2/CENP-C like AraC_binding PF02311.19 EPS27894.1 - 0.00014 21.8 0.1 0.036 14.0 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain MCM PF00493.23 EPS27895.1 - 2.5e-97 324.4 0.2 3.9e-97 323.8 0.2 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EPS27895.1 - 7.4e-32 109.9 0.0 1.6e-31 108.8 0.0 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EPS27895.1 - 3e-24 85.2 1.4 8.5e-24 83.8 1.4 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EPS27895.1 - 3.4e-11 43.7 0.0 1.3e-10 41.8 0.0 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EPS27895.1 - 5.8e-07 29.1 0.0 7.3e-06 25.5 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EPS27895.1 - 0.0043 16.9 0.0 0.011 15.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EPS27895.1 - 0.069 12.8 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain RAP1 PF07218.11 EPS27895.1 - 2 6.6 5.7 3 6.0 5.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PPR_2 PF13041.6 EPS27896.1 - 5.6e-13 48.9 1.3 2.2e-09 37.3 0.0 6.0 6 2 2 8 8 8 1 PPR repeat family PPR PF01535.20 EPS27896.1 - 3.8e-11 42.5 3.1 0.0036 17.4 0.0 8.0 10 0 0 10 10 10 2 PPR repeat PPR_3 PF13812.6 EPS27896.1 - 3.6e-09 36.6 0.0 0.0002 21.4 0.0 4.6 5 2 2 7 7 7 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 EPS27896.1 - 8.1e-06 25.4 0.0 2 8.2 0.0 5.4 6 0 0 6 6 6 2 PPR repeat PPR_long PF17177.4 EPS27896.1 - 2.8e-05 23.6 0.0 0.044 13.1 0.0 2.9 2 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 EPS27896.1 - 0.043 14.6 12.0 9.3 7.4 0.1 7.8 8 1 1 9 9 9 0 Tetratricopeptide repeat SRP68 PF16969.5 EPS27897.1 - 2.8e-192 640.6 0.0 3.2e-192 640.5 0.0 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 TPR_2 PF07719.17 EPS27897.1 - 0.029 14.5 0.1 0.13 12.4 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 EPS27897.1 - 0.049 13.5 0.0 0.23 11.4 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat p450 PF00067.22 EPS27898.1 - 1.8e-54 185.3 0.0 2.4e-54 184.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Rhodanese PF00581.20 EPS27899.1 - 1.9e-12 47.6 0.0 3e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain GTP_EFTU PF00009.27 EPS27900.1 - 6.6e-34 117.2 0.0 3.6e-33 114.7 0.0 2.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EPS27900.1 - 3.8e-20 72.0 0.1 1.2e-19 70.4 0.1 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 EPS27900.1 - 6e-12 45.8 2.0 7.9e-10 39.0 0.0 3.5 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 EPS27900.1 - 6.6e-10 38.8 0.1 2e-09 37.2 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 EPS27900.1 - 2.5e-06 27.6 0.1 1.7e-05 24.9 0.0 2.6 3 0 0 3 3 3 1 50S ribosome-binding GTPase Roc PF08477.13 EPS27900.1 - 0.0011 19.2 0.0 0.0031 17.7 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 EPS27900.1 - 0.01 15.6 0.0 0.031 14.1 0.0 2.0 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 EPS27900.1 - 0.063 13.2 0.4 0.98 9.3 0.3 2.9 2 1 0 2 2 2 0 RsgA GTPase MMS1_N PF10433.9 EPS27901.1 - 1.6e-91 307.4 0.0 2.1e-91 307.0 0.0 1.1 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EPS27901.1 - 3.7e-08 33.1 0.0 1.6e-06 27.7 0.0 2.5 2 0 0 2 2 2 2 CPSF A subunit region RabGAP-TBC PF00566.18 EPS27902.1 - 2.2e-24 86.3 0.2 3.1e-24 85.8 0.2 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Yip1 PF04893.17 EPS27903.1 - 3.3e-15 56.2 14.3 4.4e-15 55.8 14.3 1.2 1 0 0 1 1 1 1 Yip1 domain YIF1 PF03878.15 EPS27903.1 - 0.077 12.5 2.4 0.17 11.4 0.7 2.2 1 1 0 2 2 2 0 YIF1 Ribosomal_L40e PF01020.17 EPS27904.1 - 1.1e-29 102.1 12.2 1.9e-29 101.3 12.2 1.4 1 0 0 1 1 1 1 Ribosomal L40e family ubiquitin PF00240.23 EPS27904.1 - 6.6e-25 86.7 1.0 6.9e-24 83.4 0.3 2.3 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 EPS27904.1 - 3.7e-09 36.3 0.3 9.8e-09 34.9 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EPS27904.1 - 0.011 16.2 0.1 0.032 14.7 0.1 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain TBK1_ULD PF18396.1 EPS27904.1 - 0.048 13.6 0.0 0.093 12.7 0.0 1.4 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain DUF922 PF06037.11 EPS27904.1 - 0.051 13.4 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF922) DUF2407 PF10302.9 EPS27904.1 - 0.1 13.2 0.1 0.26 11.9 0.1 1.7 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain eIF-5a PF01287.20 EPS27905.1 - 6.9e-28 96.6 1.5 9.8e-28 96.1 1.5 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 EPS27905.1 - 0.0087 16.1 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Response_reg PF00072.24 EPS27905.1 - 0.021 15.0 0.0 0.042 14.0 0.0 1.4 1 0 0 1 1 1 0 Response regulator receiver domain Transposase_22 PF02994.14 EPS27905.1 - 0.14 12.4 0.2 8.8 6.6 0.0 2.8 2 1 2 4 4 4 0 L1 transposable element RBD-like domain Vps52 PF04129.12 EPS27906.1 - 4.9e-120 401.7 0.0 6.3e-120 401.3 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 EPS27906.1 - 4e-07 28.8 0.2 6.4e-07 28.2 0.2 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec3 MitMem_reg PF13012.6 EPS27906.1 - 0.01 16.2 0.6 2.4 8.6 0.4 3.3 2 1 0 2 2 2 0 Maintenance of mitochondrial structure and function Sec8_exocyst PF04048.14 EPS27906.1 - 0.02 14.8 0.5 0.061 13.2 0.5 1.8 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain InPase PF18823.1 EPS27906.1 - 0.17 11.6 0.0 0.37 10.5 0.0 1.5 1 0 0 1 1 1 0 Inorganic Pyrophosphatase BST2 PF16716.5 EPS27906.1 - 0.26 11.9 1.3 0.67 10.6 1.3 1.7 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 THOC7 PF05615.13 EPS27906.1 - 2.5 8.4 6.6 1.9 8.8 0.6 3.3 4 0 0 4 4 4 0 Tho complex subunit 7 Baculo_PEP_C PF04513.12 EPS27906.1 - 8 6.5 6.2 3.6 7.6 0.4 2.9 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DAO PF01266.24 EPS27907.1 - 1.3e-63 215.7 0.5 1.5e-63 215.5 0.5 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EPS27907.1 - 5.1e-06 26.6 0.1 1.5e-05 25.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EPS27907.1 - 0.00046 19.5 0.1 0.097 11.9 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EPS27907.1 - 0.0098 15.2 0.9 0.036 13.3 0.0 2.2 3 0 0 3 3 3 1 Thi4 family FAD_oxidored PF12831.7 EPS27907.1 - 0.013 14.9 1.3 0.085 12.2 1.3 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EPS27907.1 - 0.02 14.2 0.2 0.14 11.3 0.1 1.9 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 EPS27907.1 - 0.027 14.5 0.2 0.34 10.9 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 EPS27907.1 - 0.044 14.3 0.1 0.17 12.5 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EPS27907.1 - 0.089 11.9 1.9 0.7 8.9 2.0 1.9 1 1 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.19 EPS27907.1 - 0.14 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Fungal_trans PF04082.18 EPS27908.1 - 9.3e-15 54.4 0.5 2.6e-14 52.9 0.5 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EPS27908.1 - 2.1e-07 31.0 18.1 0.0011 19.4 7.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EPS27908.1 - 1.9e-05 24.9 7.7 1.9e-05 24.9 7.7 3.2 4 0 0 4 4 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EPS27908.1 - 0.00094 19.8 17.7 0.035 14.9 1.6 3.1 3 0 0 3 3 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EPS27908.1 - 0.0065 16.4 12.1 0.033 14.2 0.7 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EPS27908.1 - 0.0088 16.3 7.4 0.17 12.2 2.9 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 EPS27908.1 - 0.11 12.6 5.0 0.42 10.8 5.0 2.0 1 0 0 1 1 1 0 Zinc ribbon domain zf_UBZ PF18439.1 EPS27908.1 - 0.24 11.0 2.6 14 5.4 0.1 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-LYAR PF08790.11 EPS27908.1 - 0.58 10.1 4.6 7.1 6.6 0.7 2.6 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2_11 PF16622.5 EPS27908.1 - 1.3 8.8 4.7 4 7.3 0.4 2.9 3 0 0 3 3 3 0 zinc-finger C2H2-type Zn_ribbon_recom PF13408.6 EPS27908.1 - 9.7 6.8 6.8 23 5.6 6.8 1.6 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain SET PF00856.28 EPS27909.1 - 4.2e-12 46.8 0.0 9.9e-12 45.6 0.0 1.6 1 1 0 1 1 1 1 SET domain TNT PF14021.6 EPS27910.1 - 3.9e-35 120.3 0.1 6e-35 119.7 0.1 1.3 1 0 0 1 1 1 1 Tuberculosis necrotizing toxin NAD_binding_10 PF13460.6 EPS27911.1 - 1.8e-39 135.5 0.0 2.1e-39 135.3 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EPS27911.1 - 2.5e-08 33.7 0.0 3.2e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EPS27911.1 - 2.7e-07 30.4 0.1 8.3e-07 28.8 0.1 1.9 1 1 0 1 1 1 1 NmrA-like family TrkA_N PF02254.18 EPS27911.1 - 2.9e-05 24.3 0.0 6.9e-05 23.1 0.0 1.8 1 1 0 1 1 1 1 TrkA-N domain NAD_binding_4 PF07993.12 EPS27911.1 - 0.0001 21.6 0.1 0.066 12.4 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein ApbA PF02558.16 EPS27911.1 - 0.0023 17.6 0.0 0.0033 17.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GDP_Man_Dehyd PF16363.5 EPS27911.1 - 0.0075 15.7 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase DapB_N PF01113.20 EPS27911.1 - 0.02 15.0 0.0 0.035 14.2 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Shikimate_DH PF01488.20 EPS27911.1 - 0.053 13.6 0.5 0.085 12.9 0.0 1.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.15 EPS27911.1 - 0.075 13.2 0.0 0.52 10.5 0.0 2.0 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase LpxI_N PF17930.1 EPS27911.1 - 0.1 12.5 0.3 0.55 10.1 0.0 2.0 2 0 0 2 2 2 0 LpxI N-terminal domain Fungal_trans PF04082.18 EPS27912.1 - 2.7e-13 49.6 0.3 4.4e-13 48.9 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS27912.1 - 1.7e-06 28.0 17.5 4.6e-06 26.6 17.5 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M24 PF00557.24 EPS27913.1 - 2.7e-41 141.6 0.0 3.7e-41 141.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 RRM_1 PF00076.22 EPS27914.1 - 2.3e-81 267.6 5.1 7.4e-21 73.7 0.2 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 EPS27914.1 - 9.6e-30 102.6 0.5 7.5e-29 99.7 0.6 2.4 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 EPS27914.1 - 1.6e-12 47.1 0.6 0.0056 16.3 0.0 5.2 2 1 3 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EPS27914.1 - 3.9e-05 23.7 1.1 9.4 6.4 0.0 5.4 5 1 0 5 5 5 1 RNA recognition motif CbiG_mid PF11761.8 EPS27914.1 - 0.00028 20.9 0.0 3 8.0 0.0 3.6 3 0 0 3 3 3 1 Cobalamin biosynthesis central region Nup35_RRM_2 PF14605.6 EPS27914.1 - 0.0003 20.7 1.4 11 6.1 0.0 4.3 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif YflT PF11181.8 EPS27914.1 - 0.0008 19.9 5.3 0.02 15.4 1.2 3.0 3 0 0 3 3 3 1 Heat induced stress protein YflT RRM_occluded PF16842.5 EPS27914.1 - 0.0034 17.2 0.2 2.3 8.1 0.0 3.3 3 0 0 3 3 3 1 Occluded RNA-recognition motif OB_RNB PF08206.11 EPS27914.1 - 0.028 14.1 1.2 15 5.3 0.0 3.6 3 0 0 3 3 3 0 Ribonuclease B OB domain Limkain-b1 PF11608.8 EPS27914.1 - 0.5 10.5 2.5 11 6.2 0.1 3.4 3 0 0 3 3 3 0 Limkain b1 HTH_37 PF13744.6 EPS27914.1 - 1.5 8.8 4.0 29 4.7 0.8 3.5 3 0 0 3 3 3 0 Helix-turn-helix domain Presenilin PF01080.17 EPS27914.1 - 8.4 5.0 11.2 14 4.3 11.2 1.4 1 0 0 1 1 1 0 Presenilin HECT PF00632.25 EPS27915.1 - 6.9e-84 281.9 0.0 1.1e-83 281.3 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 EPS27915.1 - 0.003 17.2 3.1 0.0093 15.7 3.1 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif MRP-L27 PF09809.9 EPS27916.1 - 2.7e-15 56.2 0.1 3.4e-15 55.8 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Utp14 PF04615.13 EPS27917.1 - 1.9e-208 694.7 79.6 1.9e-208 694.7 79.6 2.2 1 1 1 2 2 2 1 Utp14 protein DUF4054 PF13262.6 EPS27917.1 - 0.013 15.5 0.4 0.066 13.2 0.4 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4054) Glyco_hydro81C PF17652.1 EPS27918.1 - 3.4e-166 552.7 2.9 4.3e-166 552.4 2.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 EPS27918.1 - 7e-116 386.9 0.3 1.1e-115 386.3 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Metallophos PF00149.28 EPS27919.1 - 1.7e-07 32.0 0.3 2.1e-06 28.4 0.3 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EPS27919.1 - 4.2e-05 23.8 0.2 0.012 15.8 0.0 2.5 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Transp_inhibit PF18791.1 EPS27919.1 - 0.052 13.1 0.4 0.13 11.7 0.4 1.6 1 0 0 1 1 1 0 Transport inhibitor response 1 protein domain Ribosomal_S8e PF01201.22 EPS27920.1 - 6.3e-55 185.1 2.1 7.3e-55 184.9 2.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e DUF2470 PF10615.9 EPS27921.1 - 9.8e-20 71.0 0.1 1.3e-19 70.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DPM2 PF07297.12 EPS27921.1 - 0.78 10.1 6.0 9.5 6.6 0.0 2.4 2 1 0 2 2 2 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) TFIIF_alpha PF05793.12 EPS27922.1 - 0.56 8.7 22.5 0.61 8.6 22.5 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RXT2_N PF08595.11 EPS27922.1 - 0.93 9.5 13.6 1.7 8.6 13.6 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal FRQ PF09421.10 EPS27922.1 - 1.9 6.4 15.6 2.1 6.2 15.6 1.0 1 0 0 1 1 1 0 Frequency clock protein Pep1_7 PF17232.2 EPS27922.1 - 4.1 7.9 7.3 4.5 7.8 0.2 2.2 1 1 1 2 2 2 0 Elicitor peptide 1-7 SPX PF03105.19 EPS27924.1 - 8.1e-41 141.2 0.5 7e-28 98.6 0.1 2.1 1 1 1 2 2 2 2 SPX domain Na_sulph_symp PF00939.19 EPS27924.1 - 8.1e-31 107.6 39.1 1.2e-30 107.0 39.1 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 EPS27924.1 - 3.7e-27 95.3 60.8 1.3e-24 87.0 36.4 2.0 2 1 1 3 3 3 2 Citrate transporter Ribosomal_S7 PF00177.21 EPS27925.1 - 2.1e-29 102.1 0.0 4.8e-29 100.9 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein S7p/S5e DUF1687 PF07955.11 EPS27925.1 - 0.92 10.0 5.5 2 8.9 5.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1687) F-box-like PF12937.7 EPS27926.1 - 2.8e-06 27.1 0.1 6.9e-06 25.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EPS27926.1 - 1.6e-05 24.7 0.0 3.1e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 F-box domain SRP40_C PF05022.12 EPS27927.1 - 1.3e-18 67.6 0.9 5.9e-18 65.5 0.9 2.3 1 0 0 1 1 1 1 SRP40, C-terminal domain SOG2 PF10428.9 EPS27927.1 - 3.4 6.8 60.2 4.9 6.2 60.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Sec3_C PF09763.9 EPS27928.1 - 2.6e-214 713.7 0.0 3.3e-214 713.3 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 EPS27928.1 - 3.7e-28 97.5 0.0 7e-28 96.6 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.12 EPS27928.1 - 0.12 11.1 0.3 0.21 10.3 0.3 1.3 1 0 0 1 1 1 0 Vps52 / Sac2 family Sec3_C_2 PF15278.6 EPS27928.1 - 0.12 12.7 0.2 0.31 11.4 0.2 1.7 1 0 0 1 1 1 0 Sec3 exocyst complex subunit DOCK_N PF16172.5 EPS27929.1 - 2.5e-109 365.7 0.2 5.4e-109 364.6 0.0 1.7 2 0 0 2 2 2 1 DOCK N-terminus DOCK-C2 PF14429.6 EPS27929.1 - 2e-38 132.2 0.0 4.8e-38 130.9 0.0 1.7 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DHR-2 PF06920.13 EPS27929.1 - 2.3e-38 132.2 1.5 8.7e-38 130.2 1.5 1.9 1 1 0 1 1 1 1 Dock homology region 2 SH3_1 PF00018.28 EPS27929.1 - 6.6e-05 22.4 0.0 0.00013 21.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EPS27929.1 - 0.00016 21.5 0.0 0.0012 18.6 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain Ofd1_CTDD PF10637.9 EPS27929.1 - 0.1 11.9 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term Na_Ca_ex PF01699.24 EPS27931.1 - 4.1e-41 140.4 41.7 1.4e-22 80.2 16.3 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein p450 PF00067.22 EPS27932.1 - 1.5e-52 178.9 0.0 2e-52 178.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CHCH PF06747.13 EPS27933.1 - 0.016 15.4 0.8 0.023 14.9 0.8 1.3 1 0 0 1 1 1 0 CHCH domain Cmc1 PF08583.10 EPS27933.1 - 0.042 13.9 1.5 0.055 13.5 1.5 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF1992 PF09350.10 EPS27934.1 - 8.9e-21 73.8 0.5 2.6e-20 72.3 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1992) TauE PF01925.19 EPS27936.1 - 0.053 13.1 0.6 0.072 12.7 0.6 1.1 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE P5CR_dimer PF14748.6 EPS27937.1 - 5.7e-19 68.3 0.8 2.8e-18 66.1 0.3 2.1 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 EPS27937.1 - 8.1e-08 32.8 0.1 2.1e-07 31.5 0.1 1.8 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.15 EPS27938.1 - 4.3e-11 42.3 0.0 5.1e-10 38.8 0.0 2.6 2 1 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 EPS27938.1 - 4.2e-06 26.9 0.0 0.00021 21.4 0.0 2.5 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Acetyltransf_8 PF13523.6 EPS27939.1 - 9.4e-51 171.3 0.1 1.4e-50 170.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EPS27939.1 - 0.036 14.7 0.0 0.071 13.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain ERG2_Sigma1R PF04622.12 EPS27940.1 - 5e-97 323.3 0.3 6e-97 323.0 0.3 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein UCR_6-4kD PF08997.10 EPS27940.1 - 0.078 12.9 0.3 13 5.8 0.0 2.5 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein RACo_C_ter PF14574.6 EPS27941.1 - 0.17 10.9 0.0 5.3 6.0 0.0 2.0 1 1 1 2 2 2 0 C-terminal domain of RACo the ASKHA domain Glyco_hydro_12 PF01670.16 EPS27942.1 - 6.5e-46 157.0 9.0 7.4e-46 156.8 9.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 DUF5640 PF18692.1 EPS27942.1 - 0.049 13.7 0.3 0.13 12.3 0.1 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5640) zf-C2H2 PF00096.26 EPS27943.1 - 0.0032 17.9 0.0 0.006 17.0 0.0 1.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type OrsD PF12013.8 EPS27943.1 - 0.074 13.5 0.0 0.11 13.0 0.0 1.2 1 0 0 1 1 1 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2_4 PF13894.6 EPS27943.1 - 0.14 13.1 0.0 0.3 12.0 0.0 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger VP4_2 PF08935.10 EPS27944.1 - 0.077 13.6 0.1 0.094 13.3 0.1 1.1 1 0 0 1 1 1 0 Viral protein VP4 subunit Cyclin_N PF00134.23 EPS27945.1 - 8.8e-12 44.9 0.0 5.1e-11 42.4 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin PF08613.11 EPS27945.1 - 3.2e-07 30.8 0.0 5.9e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Cyclin Amidohydro_2 PF04909.14 EPS27946.1 - 4.2e-35 121.9 0.0 4.9e-35 121.7 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.21 EPS27946.1 - 0.0013 18.1 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 TatD related DNase Peptidase_C14 PF00656.22 EPS27947.1 - 0.0012 18.8 0.0 0.0016 18.5 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.6 EPS27947.1 - 0.088 12.8 0.6 0.48 10.4 0.6 2.2 1 1 0 1 1 1 0 Raptor N-terminal CASPase like domain zn-ribbon_14 PF16503.5 EPS27948.1 - 7.1e-20 70.2 10.6 8e-19 66.9 1.7 3.9 4 0 0 4 4 4 2 Zinc-ribbon ATP_bind_3 PF01171.20 EPS27948.1 - 8.3e-19 68.0 0.0 1.4e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 PP-loop family RecR PF02132.15 EPS27948.1 - 0.0014 18.1 1.9 0.0014 18.1 1.9 2.6 3 0 0 3 3 3 1 RecR protein tRNA_Me_trans PF03054.16 EPS27948.1 - 0.071 11.9 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase zf-UBR PF02207.20 EPS27948.1 - 1.7 8.9 6.2 8.9 6.6 0.8 2.6 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) RasGEF PF00617.19 EPS27949.1 - 2.9e-45 154.7 0.9 4.5e-45 154.0 0.9 1.3 1 0 0 1 1 1 1 RasGEF domain Complex1_LYR_2 PF13233.6 EPS27949.1 - 1.9e-21 76.6 0.0 5.2e-21 75.2 0.0 1.8 1 0 0 1 1 1 1 Complex1_LYR-like RasGEF_N PF00618.20 EPS27949.1 - 9.2e-14 51.6 0.0 2.4e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif GTP_EFTU PF00009.27 EPS27949.1 - 0.077 12.5 0.0 6.8 6.2 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain zf-HIT PF04438.16 EPS27951.1 - 2e-08 34.0 8.0 3.2e-08 33.3 8.0 1.3 1 0 0 1 1 1 1 HIT zinc finger HalX PF08663.10 EPS27951.1 - 0.091 13.1 1.6 0.15 12.4 1.6 1.3 1 0 0 1 1 1 0 HalX domain Nfu_N PF08712.11 EPS27952.1 - 3.9e-30 103.7 0.0 2.7e-29 101.1 0.0 2.2 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 EPS27952.1 - 5.6e-28 96.9 0.2 9.5e-28 96.1 0.2 1.4 1 0 0 1 1 1 1 NifU-like domain Pox_C4_C10 PF03336.13 EPS27952.1 - 0.083 12.0 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Poxvirus C4/C10 protein PSP1 PF04468.12 EPS27954.1 - 1.6e-27 95.6 2.8 2.5e-27 94.9 2.8 1.3 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Sugar_tr PF00083.24 EPS27955.1 - 9.4e-85 285.1 18.2 1.1e-84 284.9 18.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS27955.1 - 2.2e-33 115.6 46.8 3.1e-27 95.4 24.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EPS27955.1 - 4.4e-05 22.1 2.0 4.4e-05 22.1 2.0 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.18 EPS27956.1 - 5.6e-11 42.0 0.0 1.5e-10 40.5 0.0 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS27956.1 - 1.4e-09 37.9 10.2 2.5e-09 37.1 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_88 PF07470.13 EPS27957.1 - 1.3e-07 31.1 0.3 2.8e-07 30.0 0.3 1.5 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DUF2264 PF10022.9 EPS27958.1 - 3.5e-135 450.7 0.1 4.4e-135 450.3 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) FRG1 PF06229.12 EPS27959.1 - 1.8e-54 184.4 0.0 2.9e-54 183.7 0.0 1.3 1 0 0 1 1 1 1 FRG1-like domain Fascin PF06268.13 EPS27959.1 - 0.014 15.6 0.0 0.028 14.7 0.0 1.5 1 0 0 1 1 1 0 Fascin domain Glyco_hydro_3_C PF01915.22 EPS27960.1 - 1.6e-41 142.5 0.0 3.3e-41 141.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EPS27960.1 - 2.9e-40 138.6 0.0 4.7e-40 137.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EPS27960.1 - 1.6e-22 79.3 0.1 4.4e-22 78.0 0.1 1.8 2 0 0 2 2 2 1 Fibronectin type III-like domain HECT PF00632.25 EPS27961.1 - 2.2e-72 244.1 0.0 3e-72 243.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ribosomal_L15e PF00827.17 EPS27962.1 - 4.3e-89 297.3 10.5 5.2e-89 297.0 10.5 1.0 1 0 0 1 1 1 1 Ribosomal L15 zf-RING_2 PF13639.6 EPS27963.1 - 3.3e-12 46.5 8.1 3.3e-12 46.5 8.1 1.9 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 EPS27963.1 - 7.6e-10 38.9 6.1 1.6e-09 37.9 6.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EPS27963.1 - 7e-09 35.3 4.3 1.6e-08 34.1 4.3 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EPS27963.1 - 5e-08 32.6 7.9 1.1e-07 31.5 7.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPS27963.1 - 1.2e-05 25.1 6.0 2.4e-05 24.1 6.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EPS27963.1 - 3.1e-05 23.7 7.3 7.4e-05 22.5 7.3 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EPS27963.1 - 4.1e-05 23.4 5.3 4.1e-05 23.4 5.3 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPS27963.1 - 8.6e-05 22.5 2.7 0.00012 22.0 1.3 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EPS27963.1 - 0.00011 22.1 6.2 0.00025 21.0 6.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EPS27963.1 - 0.0018 18.3 4.1 0.0018 18.3 4.1 1.9 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H_2 PF13832.6 EPS27963.1 - 0.031 14.5 2.1 0.068 13.3 2.1 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain FNIP_M PF14637.6 EPS27963.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Folliculin-interacting protein middle domain Zn_ribbon_17 PF17120.5 EPS27963.1 - 0.85 9.3 13.1 0.059 13.0 8.0 1.7 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 EPS27963.1 - 1.1 9.5 6.5 2.3 8.4 6.5 1.6 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 EPS27963.1 - 1.2 9.4 6.6 6.7 7.0 6.6 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 EPS27963.1 - 1.2 9.5 6.7 3.6 8.0 6.3 2.1 1 1 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.6 EPS27963.1 - 1.2 9.3 10.4 0.1 12.7 4.5 2.3 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Ada3 PF10198.9 EPS27964.1 - 2.1e-47 160.6 1.3 2.1e-47 160.6 1.3 2.0 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 NPR2 PF06218.11 EPS27965.1 - 1.8e-132 442.2 0.0 2.6e-131 438.4 0.0 2.4 1 1 0 1 1 1 1 Nitrogen permease regulator 2 DUF4250 PF14056.6 EPS27965.1 - 0.068 13.1 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) NPR3 PF03666.13 EPS27965.1 - 0.15 10.9 0.0 1.3 7.7 0.0 2.0 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF1656 PF07869.12 EPS27966.1 - 0.13 12.3 2.7 0.23 11.5 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) Lactamase_B_2 PF12706.7 EPS27967.1 - 1.3e-07 31.3 0.0 3.4e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EPS27967.1 - 2.1e-07 31.1 0.0 4.6e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DRMBL PF07522.14 EPS27967.1 - 0.0033 17.6 0.0 0.087 13.0 0.0 2.5 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase Sporozoite_P67 PF05642.11 EPS27967.1 - 0.0038 15.4 6.1 0.0063 14.7 6.1 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen DNA_pol_phi PF04931.13 EPS27967.1 - 1.8 6.5 20.8 0.02 13.0 13.4 1.4 2 0 0 2 2 2 0 DNA polymerase phi TRAP_alpha PF03896.16 EPS27967.1 - 4.5 6.4 8.4 10 5.2 8.4 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.14 EPS27967.1 - 5.5 5.1 16.2 0.091 11.0 8.3 1.8 2 0 0 2 2 2 0 CDC45-like protein PBP1_TM PF14812.6 EPS27967.1 - 8.9 6.8 9.8 29 5.1 9.8 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nop14 PF04147.12 EPS27967.1 - 9.3 4.3 23.1 16 3.5 23.1 1.4 1 1 0 1 1 1 0 Nop14-like family Amidohydro_1 PF01979.20 EPS27968.1 - 1.1e-73 248.6 1.6 2.2e-73 247.6 1.0 1.7 2 0 0 2 2 2 1 Amidohydrolase family Urease_alpha PF00449.20 EPS27968.1 - 1.2e-56 190.3 0.9 2.1e-56 189.4 0.9 1.4 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.20 EPS27968.1 - 1.5e-40 137.2 0.2 1.1e-39 134.4 0.0 2.2 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.18 EPS27968.1 - 6.4e-35 119.4 0.1 1.5e-34 118.2 0.1 1.6 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_3 PF07969.11 EPS27968.1 - 1.3e-09 38.1 0.4 3.9e-06 26.6 0.0 2.8 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_2 PF04909.14 EPS27968.1 - 0.15 11.8 0.0 0.36 10.6 0.0 1.6 1 0 0 1 1 1 0 Amidohydrolase HMG_box PF00505.19 EPS27969.1 - 4e-11 43.2 2.8 8e-11 42.2 2.8 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EPS27969.1 - 2.5e-07 31.2 2.5 5.3e-07 30.1 2.5 1.6 1 0 0 1 1 1 1 HMG-box domain KRAB PF01352.27 EPS27969.1 - 0.0055 16.3 0.1 0.0096 15.6 0.1 1.3 1 0 0 1 1 1 1 KRAB box NAD_binding_1 PF00175.21 EPS27970.1 - 2.6e-32 111.7 0.0 3.9e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EPS27970.1 - 7.7e-24 83.9 0.0 1.8e-23 82.7 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EPS27970.1 - 1.9e-08 34.5 0.0 0.0001 22.4 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain B12D PF06522.11 EPS27970.1 - 0.0031 17.3 0.0 0.26 11.1 0.0 2.6 2 0 0 2 2 2 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Ribosomal_L18A PF01775.17 EPS27971.1 - 7.4e-54 181.0 0.2 9.8e-54 180.6 0.2 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A PCI PF01399.27 EPS27972.1 - 9.1e-11 42.2 0.0 1.9e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 PCI domain DUF433 PF04255.14 EPS27972.1 - 0.057 13.3 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF433) BTB PF00651.31 EPS27973.1 - 0.00015 22.0 0.0 0.00029 21.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain CLTH PF10607.9 EPS27974.1 - 2.9e-34 118.1 0.0 7.2e-34 116.8 0.0 1.7 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 EPS27974.1 - 9.4e-08 32.0 0.2 1.8e-07 31.1 0.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 EPS27974.1 - 8.6e-05 22.0 0.1 0.00016 21.1 0.1 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_5 PF14634.6 EPS27974.1 - 0.00012 21.9 0.4 0.00025 21.0 0.2 1.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 EPS27974.1 - 0.0017 18.7 0.4 0.003 17.8 0.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EPS27974.1 - 0.0087 15.9 0.8 0.018 14.9 0.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EPS27974.1 - 0.014 15.3 0.6 0.026 14.4 0.6 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EPS27974.1 - 0.02 14.7 0.4 0.036 13.9 0.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPS27974.1 - 0.034 14.0 0.4 0.064 13.1 0.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FAP206 PF12018.8 EPS27974.1 - 0.045 13.3 0.0 0.081 12.4 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function Corona_S2 PF01601.16 EPS27974.1 - 0.06 11.8 1.1 0.083 11.4 1.1 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Flagellin_C PF00700.21 EPS27974.1 - 0.12 12.8 0.6 0.34 11.3 0.6 1.8 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region Nsp1_C PF05064.13 EPS27975.1 - 0.011 15.5 0.6 0.03 14.1 0.2 1.9 2 0 0 2 2 2 0 Nsp1-like C-terminal region DUF2203 PF09969.9 EPS27975.1 - 0.064 14.0 0.5 11 6.8 0.1 3.2 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) EzrA PF06160.12 EPS27975.1 - 0.074 11.2 0.1 0.11 10.6 0.1 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA zf-Tim10_DDP PF02953.15 EPS27976.1 - 2.8e-22 78.1 1.3 3.3e-22 77.9 1.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger tRNA-synt_2 PF00152.20 EPS27977.1 - 7.1e-64 215.8 0.0 9.2e-64 215.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EPS27977.1 - 2.2e-10 40.4 0.0 3.9e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EPS27977.1 - 1.2e-06 28.2 0.0 0.00052 19.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti_2 PF13742.6 EPS27977.1 - 0.0094 16.1 0.0 0.086 13.0 0.0 2.1 1 1 1 2 2 2 2 OB-fold nucleic acid binding domain 2OG-FeII_Oxy PF03171.20 EPS27978.1 - 0.00027 21.4 0.0 0.00064 20.2 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EPS27978.1 - 0.064 14.0 0.0 0.11 13.2 0.0 1.4 1 0 0 1 1 1 0 non-haem dioxygenase in morphine synthesis N-terminal Clr2 PF10383.9 EPS27979.1 - 5.6e-31 108.3 0.0 1.1e-30 107.4 0.0 1.4 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 ABC_membrane_2 PF06472.15 EPS27980.1 - 3.6e-87 292.2 0.0 6.6e-87 291.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EPS27980.1 - 1.5e-13 51.4 0.0 2.8e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 EPS27980.1 - 0.016 15.8 0.2 1 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 EPS27980.1 - 0.017 14.8 0.0 0.06 13.1 0.0 1.9 3 0 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 EPS27980.1 - 0.045 13.1 0.1 0.078 12.4 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_29 PF13555.6 EPS27980.1 - 0.092 12.5 0.0 0.31 10.8 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain ALIX_LYPXL_bnd PF13949.6 EPS27980.1 - 0.12 11.6 0.1 0.2 10.9 0.1 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV AAA PF00004.29 EPS27980.1 - 0.18 12.3 0.0 0.54 10.7 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NIF PF03031.18 EPS27981.1 - 1.1e-54 184.4 0.2 1.5e-54 184.0 0.2 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase LRR_4 PF12799.7 EPS27982.1 - 6.3e-47 156.8 73.5 1.7e-08 34.6 0.8 7.3 1 1 11 12 12 12 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EPS27982.1 - 3.7e-21 74.7 32.8 2.4e-06 27.2 2.2 6.4 1 1 5 7 7 7 7 Leucine rich repeat LRR_9 PF14580.6 EPS27982.1 - 9.1e-16 57.8 17.8 1.5e-06 27.8 2.3 4.2 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 EPS27982.1 - 1.9e-06 27.5 21.0 0.15 12.1 0.2 7.7 7 1 1 8 8 8 3 Leucine Rich repeat LRR_1 PF00560.33 EPS27982.1 - 4.9e-06 26.4 24.7 10 7.1 0.1 9.4 10 0 0 10 10 10 3 Leucine Rich Repeat Aldo_ket_red PF00248.21 EPS27984.1 - 2.1e-42 145.3 0.0 2.6e-42 145.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family COX14 PF14880.6 EPS27986.1 - 0.11 12.4 0.1 0.3 11.0 0.0 1.7 2 0 0 2 2 2 0 Cytochrome oxidase c assembly TEA PF01285.18 EPS27987.1 - 1.6e-27 95.3 0.0 4.1e-27 94.0 0.0 1.7 1 0 0 1 1 1 1 TEA/ATTS domain RRM_1 PF00076.22 EPS27989.1 - 6e-73 240.6 0.6 8.6e-18 63.9 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EPS27989.1 - 3.1e-07 30.1 0.0 0.33 10.8 0.0 4.7 5 0 0 5 5 5 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EPS27989.1 - 2.2e-06 27.6 0.0 0.65 10.0 0.0 3.8 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 EPS27989.1 - 8.7e-06 25.3 0.0 0.045 13.3 0.0 3.7 3 1 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EPS27989.1 - 5.8e-05 23.1 0.0 3.8 7.7 0.0 3.7 3 0 0 3 3 3 2 RNA recognition motif Limkain-b1 PF11608.8 EPS27989.1 - 0.0062 16.6 0.6 26 5.0 0.0 4.6 5 0 0 5 5 5 0 Limkain b1 RNA_bind PF08675.11 EPS27989.1 - 0.016 15.2 0.0 1.6 8.8 0.0 3.1 3 0 0 3 3 3 0 RNA binding domain Dynein_light PF01221.18 EPS27990.1 - 3.3e-39 133.1 2.3 3.9e-39 132.9 2.3 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 zinc_ribbon_15 PF17032.5 EPS27991.1 - 0.0017 19.0 1.0 0.0025 18.5 1.0 1.3 1 0 0 1 1 1 1 zinc-ribbon family zf-LITAF-like PF10601.9 EPS27991.1 - 0.31 11.3 8.4 2.2 8.6 0.8 2.2 1 1 1 2 2 2 0 LITAF-like zinc ribbon domain SSF PF00474.17 EPS27992.1 - 3.7e-18 65.6 32.1 7.2e-18 64.6 32.1 1.5 1 0 0 1 1 1 1 Sodium:solute symporter family Sec61_beta PF03911.16 EPS27993.1 - 3.5e-17 62.1 0.4 5.7e-17 61.5 0.4 1.3 1 0 0 1 1 1 1 Sec61beta family SCIMP PF15050.6 EPS27994.1 - 0.32 11.5 5.9 0.8 10.2 0.0 3.5 4 0 0 4 4 4 0 SCIMP protein DUF4448 PF14610.6 EPS27994.1 - 0.65 9.7 3.2 0.68 9.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) FMN_dh PF01070.18 EPS27995.1 - 4.6e-104 348.2 0.0 5.3e-104 348.0 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 EPS27995.1 - 0.00034 19.7 0.5 0.00056 19.0 0.5 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 EPS27995.1 - 0.0023 17.1 0.3 0.0034 16.6 0.3 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.21 EPS27995.1 - 0.012 15.1 0.4 0.026 14.0 0.2 1.6 2 0 0 2 2 2 0 Histidine biosynthesis protein ThiG PF05690.14 EPS27995.1 - 0.05 12.9 1.0 0.24 10.7 0.6 2.2 2 1 0 2 2 2 0 Thiazole biosynthesis protein ThiG HRI1 PF16815.5 EPS27996.1 - 2.4e-30 105.9 1.7 6.3e-30 104.6 1.7 1.6 1 1 0 1 1 1 1 Protein HRI1 PCNA_C PF02747.15 EPS27998.1 - 4.3e-52 175.6 0.0 1.5e-51 173.9 0.0 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.18 EPS27998.1 - 3.1e-33 114.2 0.4 6.7e-33 113.1 0.4 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad1 PF02144.16 EPS27998.1 - 0.0021 17.2 0.3 0.0036 16.4 0.3 1.3 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 EPS27998.1 - 0.0036 16.8 0.0 0.0044 16.5 0.0 1.1 1 0 0 1 1 1 1 Rad9 Vezatin PF12632.7 EPS27999.1 - 8.8e-70 235.3 0.1 1.5e-68 231.2 0.0 2.1 2 0 0 2 2 2 2 Mysoin-binding motif of peroxisomes IQ PF00612.27 EPS28000.1 - 0.0053 16.4 0.4 0.012 15.3 0.4 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif 2OG-FeII_Oxy PF03171.20 EPS28001.1 - 2.5e-13 50.3 0.0 6e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EPS28001.1 - 1.8e-12 48.0 0.0 4.4e-12 46.8 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal DUF3336 PF11815.8 EPS28002.1 - 9e-46 155.0 3.7 1.4e-45 154.4 3.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EPS28002.1 - 5.8e-17 62.5 1.2 4.1e-16 59.8 0.1 2.9 3 2 1 4 4 4 1 Patatin-like phospholipase GHMP_kinases_C PF08544.13 EPS28002.1 - 0.21 12.0 0.3 1.3 9.4 0.0 2.5 3 0 0 3 3 3 0 GHMP kinases C terminal LRR_8 PF13855.6 EPS28003.1 - 4.2e-14 52.0 11.7 1.2e-08 34.6 3.3 4.0 2 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 EPS28003.1 - 5.2e-11 42.6 7.5 0.0083 16.5 0.1 4.4 2 1 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EPS28003.1 - 0.0022 17.5 0.8 0.099 12.1 0.4 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 EPS28003.1 - 0.0033 17.7 10.9 25 6.0 0.1 6.4 5 1 0 5 5 5 1 Leucine Rich Repeat LRR_6 PF13516.6 EPS28003.1 - 0.012 15.6 10.2 12 6.3 0.8 5.2 5 0 0 5 5 5 0 Leucine Rich repeat Metallophos PF00149.28 EPS28004.1 - 4e-40 138.5 0.1 5.2e-40 138.1 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EPS28004.1 - 1.1e-22 80.2 2.7 1.4e-22 79.8 1.8 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Arf PF00025.21 EPS28006.1 - 2.3e-64 216.1 0.0 2.5e-64 215.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EPS28006.1 - 1.1e-10 41.3 0.0 4.3e-07 29.4 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EPS28006.1 - 5.1e-08 32.6 0.0 6.7e-08 32.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EPS28006.1 - 9.2e-07 29.0 0.0 1.2e-06 28.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 EPS28006.1 - 1e-06 28.9 0.0 3e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EPS28006.1 - 3.9e-05 23.3 0.0 5.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EPS28006.1 - 0.00023 20.6 0.0 0.00025 20.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region cobW PF02492.19 EPS28006.1 - 0.028 14.0 0.0 1.9 8.0 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 EPS28006.1 - 0.13 11.8 0.0 3.3 7.2 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain DUF2457 PF10446.9 EPS28007.1 - 4.9e-159 530.4 27.5 4.9e-159 530.4 27.5 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF2457) VID27_N PF17748.1 EPS28007.1 - 0.037 13.9 7.1 0.07 13.0 7.1 1.4 1 0 0 1 1 1 0 VID27 N-terminal region TFIIA PF03153.13 EPS28007.1 - 0.12 12.3 14.5 0.3 11.1 14.5 1.7 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.12 EPS28007.1 - 1.1 7.4 21.5 1.7 6.8 21.5 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 EPS28007.1 - 4.3 6.7 17.8 8.9 5.6 17.8 1.6 1 0 0 1 1 1 0 SDA1 TPR_19 PF14559.6 EPS28009.1 - 3.1e-17 62.9 8.9 3e-05 24.4 0.0 7.5 5 2 3 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 EPS28009.1 - 5.4e-12 45.2 0.2 0.049 14.0 0.1 6.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 EPS28009.1 - 8.9e-12 44.2 18.7 0.0033 17.4 0.0 8.7 10 0 0 10 10 8 4 Tetratricopeptide repeat TPR_14 PF13428.6 EPS28009.1 - 1.3e-10 41.2 18.2 0.39 11.7 0.1 9.0 6 2 3 9 9 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 EPS28009.1 - 1.3e-10 40.6 11.2 0.094 12.6 0.0 8.6 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_8 PF13181.6 EPS28009.1 - 4e-09 36.0 6.5 0.084 13.1 0.1 7.0 6 0 0 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EPS28009.1 - 1.1e-07 32.0 10.6 0.04 14.1 0.2 6.6 5 1 1 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 EPS28009.1 - 2.2e-07 31.4 2.9 0.0064 17.1 0.0 4.9 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 EPS28009.1 - 1.6e-05 24.4 1.1 3.2 7.5 0.0 6.0 6 0 0 6 6 6 1 TPR repeat TPR_7 PF13176.6 EPS28009.1 - 2.2e-05 24.2 10.4 0.36 11.0 0.0 6.7 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 EPS28009.1 - 0.00053 20.2 15.0 0.14 12.4 0.1 6.1 6 2 1 7 7 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 EPS28009.1 - 0.0009 18.5 3.7 4.3 6.5 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat NARP1 PF12569.8 EPS28009.1 - 0.0092 14.9 0.4 1.8 7.4 0.0 2.9 3 1 0 3 3 3 1 NMDA receptor-regulated protein 1 TPR_9 PF13371.6 EPS28009.1 - 0.023 14.9 7.7 0.026 14.7 0.1 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.20 EPS28009.1 - 0.36 11.2 0.9 9.2 6.8 0.1 3.3 3 0 0 3 3 2 0 PPR repeat TPR_6 PF13174.6 EPS28009.1 - 0.78 10.5 7.1 29 5.6 0.0 6.2 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 EPS28009.1 - 5.3 8.0 10.0 22 6.0 0.1 5.8 7 0 0 7 7 6 0 Tetratricopeptide repeat SAM_2 PF07647.17 EPS28010.1 - 1.5e-08 34.6 0.1 4.2e-08 33.2 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EPS28010.1 - 0.00039 20.8 0.1 0.001 19.5 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4508 PF14969.6 EPS28010.1 - 0.074 13.3 0.2 0.16 12.3 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4508) MerR-DNA-bind PF09278.11 EPS28010.1 - 0.64 10.6 4.6 0.54 10.8 0.7 2.7 2 0 0 2 2 2 0 MerR, DNA binding Rab5ip PF07019.12 EPS28011.1 - 8.7e-22 77.5 5.3 1.3e-21 77.0 5.3 1.2 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Sulfate_transp PF00916.20 EPS28012.1 - 1.5e-108 363.0 20.5 2e-108 362.5 20.5 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EPS28012.1 - 4.9e-09 35.8 0.0 9.7e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EPS28012.1 - 0.0023 18.3 4.6 0.0023 18.3 4.6 3.4 2 2 1 3 3 3 1 Molybdate transporter of MFS superfamily YbjM PF11045.8 EPS28012.1 - 0.024 14.8 2.9 0.12 12.6 0.1 3.0 3 0 0 3 3 3 0 Putative inner membrane protein of Enterobacteriaceae SLATT_4 PF18186.1 EPS28012.1 - 0.11 12.1 0.0 0.37 10.4 0.0 1.9 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 SNN_transmemb PF09049.10 EPS28012.1 - 1.8 8.5 9.8 0.068 13.1 2.0 2.8 2 0 0 2 2 2 0 Stannin transmembrane CC PF04942.14 EPS28013.1 - 0.002 18.3 0.9 0.0043 17.2 0.9 1.6 1 0 0 1 1 1 1 CC domain Acetyltransf_1 PF00583.25 EPS28014.1 - 7.1e-09 35.9 0.0 1.1e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EPS28014.1 - 1.1e-06 28.6 0.0 1.6e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPS28014.1 - 2.8e-06 27.2 0.0 4.9e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EPS28014.1 - 3.4e-06 27.4 0.0 5.2e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EPS28014.1 - 0.024 14.7 0.1 0.04 14.0 0.1 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.16 EPS28015.1 - 1.9e-20 73.1 55.8 5.2e-14 51.9 36.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4808 PF16066.5 EPS28015.1 - 0.056 14.0 0.0 0.098 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4808) RNA_pol_Rpb6 PF01192.22 EPS28016.1 - 6.5e-17 61.2 0.1 1e-16 60.6 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 KOW PF00467.29 EPS28016.1 - 0.062 13.3 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 KOW motif zf-C2H2 PF00096.26 EPS28017.1 - 1.5e-30 104.0 63.6 5.8e-06 26.5 0.7 11.3 11 1 1 12 12 12 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPS28017.1 - 4e-18 64.6 61.9 0.029 15.2 0.1 11.4 11 0 0 11 11 11 7 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EPS28017.1 - 2.1e-15 56.3 54.0 0.0014 19.0 0.7 10.8 10 0 0 10 10 10 7 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EPS28017.1 - 5.7e-08 32.8 14.6 1.2 9.5 0.1 8.6 9 0 0 9 9 9 2 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 EPS28017.1 - 8.2e-05 22.8 30.1 0.029 14.7 0.7 6.2 3 1 5 8 8 8 4 C2H2-type zinc ribbon FOXP-CC PF16159.5 EPS28017.1 - 0.001 19.6 35.5 4.5 8.0 0.5 9.0 5 2 4 9 9 9 3 FOXP coiled-coil domain GAGA PF09237.11 EPS28017.1 - 0.0045 16.8 2.0 0.0045 16.8 2.0 2.9 3 0 0 3 3 3 1 GAGA factor zf-C2H2_aberr PF17017.5 EPS28017.1 - 0.11 12.6 0.3 0.11 12.6 0.3 5.9 5 1 2 7 7 7 0 Aberrant zinc-finger YdjO PF14169.6 EPS28017.1 - 0.31 10.8 6.9 4.8 7.0 0.0 4.3 4 0 0 4 4 4 0 Cold-inducible protein YdjO TLP1_add_C PF18313.1 EPS28018.1 - 7.2e-19 67.5 0.1 1.6e-18 66.4 0.1 1.6 1 0 0 1 1 1 1 Thiolase-like protein type 1 additional C-terminal domain ECH_1 PF00378.20 EPS28019.1 - 2.7e-45 154.6 0.0 3.3e-45 154.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EPS28019.1 - 2.1e-24 86.7 0.0 2.8e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 EPS28019.1 - 0.0047 16.9 0.0 0.028 14.4 0.0 2.0 2 0 0 2 2 2 1 Peptidase family S49 HRI1 PF16815.5 EPS28020.1 - 9.9e-29 100.7 0.4 7.6e-28 97.8 0.4 1.9 1 1 0 1 1 1 1 Protein HRI1 PH PF00169.29 EPS28021.1 - 3.5e-08 33.9 0.1 2.3e-07 31.3 0.0 2.5 2 1 0 2 2 2 1 PH domain PH_9 PF15410.6 EPS28021.1 - 0.087 13.2 0.1 0.28 11.6 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain COPIIcoated_ERV PF07970.12 EPS28022.1 - 7.6e-83 277.7 0.0 1.3e-82 277.0 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EPS28022.1 - 6.3e-31 106.6 0.1 6.1e-30 103.4 0.0 2.1 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) TAP_C PF03943.13 EPS28023.1 - 5.7e-18 64.3 0.7 1.4e-17 63.0 0.7 1.7 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.7 EPS28023.1 - 1.7e-05 25.1 10.9 0.00037 20.8 2.0 2.5 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) NTF2 PF02136.20 EPS28023.1 - 1.9e-05 25.2 0.0 4.2e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_8 PF13855.6 EPS28023.1 - 3.2e-05 23.6 1.1 6.4e-05 22.6 1.1 1.5 1 0 0 1 1 1 1 Leucine rich repeat LRR_9 PF14580.6 EPS28023.1 - 0.00025 20.6 0.1 0.00042 19.9 0.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeat RRM_9 PF18444.1 EPS28023.1 - 0.0051 16.6 0.0 0.015 15.2 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif LRR_6 PF13516.6 EPS28023.1 - 0.029 14.4 2.1 1.3 9.3 0.6 3.4 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 EPS28023.1 - 0.19 12.4 1.5 28 5.8 0.2 3.2 3 0 0 3 3 3 0 Leucine Rich Repeat Vps53_N PF04100.12 EPS28025.1 - 3e-106 355.6 5.7 3e-106 355.6 5.7 1.7 2 0 0 2 2 2 1 Vps53-like, N-terminal Vps54_N PF10475.9 EPS28025.1 - 1.9e-07 30.6 8.4 4.2e-07 29.5 8.4 1.5 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex RINT1_TIP1 PF04437.13 EPS28025.1 - 4.6e-06 25.8 1.5 4.6e-06 25.8 1.5 3.0 2 2 0 2 2 2 1 RINT-1 / TIP-1 family COG2 PF06148.11 EPS28025.1 - 2.8e-05 24.2 5.7 3.3e-05 24.0 3.2 2.5 3 0 0 3 3 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF2451 PF10474.9 EPS28025.1 - 0.00016 21.5 0.1 0.00016 21.5 0.1 2.1 2 1 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) Atg14 PF10186.9 EPS28025.1 - 0.013 14.6 5.7 0.032 13.3 5.7 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Sigma70_ner PF04546.13 EPS28025.1 - 0.027 14.4 3.5 0.081 12.8 3.5 1.8 1 0 0 1 1 1 0 Sigma-70, non-essential region NBD94 PF16830.5 EPS28025.1 - 0.23 11.9 2.4 0.59 10.6 2.4 1.6 1 0 0 1 1 1 0 Nucleotide-Binding Domain 94 of RH Syntaxin_2 PF14523.6 EPS28025.1 - 0.24 11.8 5.8 3.7 8.0 4.0 3.3 2 0 0 2 2 2 0 Syntaxin-like protein APG6_N PF17675.1 EPS28025.1 - 0.24 11.9 10.5 0.049 14.2 5.9 2.2 2 0 0 2 2 1 0 Apg6 coiled-coil region Spc7 PF08317.11 EPS28025.1 - 0.42 9.4 14.1 0.024 13.5 8.2 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF1515 PF07439.11 EPS28025.1 - 0.44 10.6 5.5 0.61 10.1 1.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) FapA PF03961.13 EPS28025.1 - 0.48 9.0 2.0 0.98 7.9 2.0 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A Baculo_PEP_C PF04513.12 EPS28025.1 - 0.59 10.2 8.1 0.69 10.0 5.3 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.11 EPS28025.1 - 1.2 9.2 8.5 0.51 10.4 1.6 3.2 2 1 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Sec8_exocyst PF04048.14 EPS28025.1 - 2.7 7.9 8.8 0.4 10.6 3.8 2.3 3 0 0 3 3 1 0 Sec8 exocyst complex component specific domain DUF5339 PF17274.2 EPS28025.1 - 4.9 8.1 9.1 11 7.0 0.3 3.3 2 1 1 3 3 3 0 Family of unknown function (DUF5339) DUF5082 PF16888.5 EPS28025.1 - 5.6 7.3 11.0 2.6 8.3 1.0 3.3 2 1 0 3 3 3 0 Domain of unknown function (DUF5082) DUF1664 PF07889.12 EPS28025.1 - 7.9 6.5 8.8 2.8 8.0 2.9 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Ribosomal_L10 PF00466.20 EPS28026.1 - 1.6e-23 82.7 0.4 3.3e-23 81.7 0.2 1.6 2 0 0 2 2 2 1 Ribosomal protein L10 RL10P_insert PF17777.1 EPS28026.1 - 7.2e-22 77.2 0.0 1.5e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 EPS28026.1 - 5.7e-19 68.5 3.0 5.7e-19 68.5 3.0 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein Sda PF08970.10 EPS28026.1 - 0.095 12.5 0.3 14 5.5 0.1 2.7 2 0 0 2 2 2 0 Sporulation inhibitor A Holin_SPP1 PF04688.13 EPS28026.1 - 0.13 12.5 0.1 0.4 10.9 0.1 1.9 2 0 0 2 2 2 0 SPP1 phage holin WD40 PF00400.32 EPS28027.1 - 0.013 16.3 0.8 0.4 11.6 0.5 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat Cuticle_1 PF08140.11 EPS28027.1 - 9 6.4 6.2 2.4 8.2 0.4 2.8 3 0 0 3 3 3 0 Crustacean cuticle protein repeat URO-D PF01208.17 EPS28028.1 - 1.1e-129 432.5 0.0 1.3e-129 432.4 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) dCMP_cyt_deam_1 PF00383.23 EPS28029.1 - 2.8e-23 81.7 0.0 3.6e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EPS28029.1 - 4.7e-20 71.7 0.0 5.5e-20 71.5 0.0 1.0 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 EPS28029.1 - 4e-05 23.7 0.7 0.14 12.2 1.0 2.2 1 1 1 2 2 2 2 Bd3614-like deaminase SNAD4 PF18750.1 EPS28029.1 - 0.00065 19.8 0.0 0.0032 17.6 0.0 1.9 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC_N PF08210.11 EPS28029.1 - 0.0091 15.9 0.1 0.019 14.8 0.1 1.5 1 1 0 1 1 1 1 APOBEC-like N-terminal domain NAD1 PF18778.1 EPS28029.1 - 0.014 15.5 0.0 0.064 13.4 0.0 1.8 2 0 0 2 2 2 0 Novel AID APOBEC clade 1 NAD2 PF18782.1 EPS28029.1 - 0.015 15.5 0.0 0.056 13.6 0.0 1.7 2 0 0 2 2 2 0 Novel AID APOBEC clade 2 APOBEC2 PF18772.1 EPS28029.1 - 0.021 14.9 0.1 0.084 12.9 0.0 1.8 1 1 1 2 2 2 0 APOBEC2 XOO_2897-deam PF14440.6 EPS28029.1 - 0.15 12.1 0.1 0.33 11.1 0.0 1.5 2 0 0 2 2 2 0 Xanthomonas XOO_2897-like deaminase DnaJ_C PF01556.18 EPS28030.1 - 1.3e-38 132.5 0.3 1.7e-38 132.0 0.3 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EPS28030.1 - 4.4e-25 87.6 1.7 7.7e-25 86.8 1.7 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EPS28030.1 - 3.6e-16 59.3 19.9 6.5e-16 58.5 19.9 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 EPS28030.1 - 1.4 8.9 10.9 0.87 9.6 2.6 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 EPS28030.1 - 3.9 7.5 18.8 0.092 12.7 3.1 2.5 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein DUF2614 PF11023.8 EPS28030.1 - 6.3 6.9 6.2 3.6 7.7 1.0 2.1 1 1 1 2 2 2 0 Zinc-ribbon containing domain Atg14 PF10186.9 EPS28031.1 - 0.046 12.8 1.7 0.08 12.0 1.7 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF5089 PF17002.5 EPS28031.1 - 0.12 12.2 0.6 0.21 11.5 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5089) PCI PF01399.27 EPS28032.1 - 6.5e-10 39.5 5.0 1.1e-09 38.8 0.0 3.5 3 0 0 3 3 3 1 PCI domain G-gamma PF00631.22 EPS28033.1 - 3.4e-24 84.6 0.0 3.9e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 GGL domain DUF3220 PF11516.8 EPS28033.1 - 0.061 13.5 0.0 0.082 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) Rdx PF10262.9 EPS28034.1 - 2.2e-31 107.9 0.0 3.4e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 Rdx family Het-C PF07217.11 EPS28034.1 - 0.049 12.2 0.0 0.06 11.9 0.0 1.0 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C CHZ PF09649.10 EPS28035.1 - 0.002 17.5 1.1 0.0035 16.8 0.1 2.0 2 0 0 2 2 2 1 Histone chaperone domain CHZ Sec3_C_2 PF15278.6 EPS28035.1 - 0.069 13.5 0.4 0.084 13.2 0.4 1.2 1 0 0 1 1 1 0 Sec3 exocyst complex subunit Heme_oxygenase PF01126.20 EPS28036.1 - 0.00019 21.3 0.0 0.14 11.9 0.0 2.8 3 0 0 3 3 3 2 Heme oxygenase DUF111 PF01969.17 EPS28036.1 - 0.063 12.4 0.2 0.11 11.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF111 PDEase_I PF00233.19 EPS28038.1 - 7.5e-71 238.6 0.0 1.1e-70 238.1 0.0 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase ADH_zinc_N PF00107.26 EPS28039.1 - 6.2e-26 90.9 0.1 9.9e-26 90.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPS28039.1 - 5.3e-18 66.4 0.0 8.5e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPS28039.1 - 2.7e-09 36.9 0.0 1.8e-07 31.0 0.0 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain zf-HC5HC2H_2 PF13832.6 EPS28040.1 - 9.4e-21 74.1 1.0 9.4e-21 74.1 1.0 4.2 4 0 0 4 4 4 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EPS28040.1 - 1.4e-18 66.9 1.9 1.4e-18 66.9 1.9 4.2 4 0 0 4 4 3 1 PHD-like zinc-binding domain BAH PF01426.18 EPS28040.1 - 3.2e-18 65.8 0.0 5.8e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 BAH domain PHD_2 PF13831.6 EPS28040.1 - 2.9e-09 36.3 3.0 2.9e-09 36.3 3.0 4.6 6 0 0 6 6 4 1 PHD-finger PHD PF00628.29 EPS28040.1 - 9.7e-09 35.0 46.4 1.1e-06 28.5 5.6 5.4 6 0 0 6 6 6 2 PHD-finger Myb_DNA-binding PF00249.31 EPS28040.1 - 5.2e-05 23.3 0.6 0.00029 21.0 0.0 2.5 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EPS28040.1 - 0.14 12.4 0.0 0.42 10.9 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain NIPSNAP PF07978.13 EPS28040.1 - 0.17 12.1 0.0 0.58 10.4 0.0 1.9 2 0 0 2 2 1 0 NIPSNAP C1_2 PF03107.16 EPS28040.1 - 0.58 10.5 29.3 0.18 12.1 0.3 5.4 5 0 0 5 5 5 0 C1 domain ELM2 PF01448.24 EPS28040.1 - 1.5 9.6 4.0 4 8.3 0.9 2.9 2 1 0 2 2 2 0 ELM2 domain UPF0547 PF10571.9 EPS28040.1 - 2.4 8.3 10.3 0.038 14.1 2.4 2.3 2 0 0 2 2 1 0 Uncharacterised protein family UPF0547 JTB PF05439.12 EPS28040.1 - 2.8 8.0 5.7 1.5 8.9 1.2 2.4 2 0 0 2 2 2 0 Jumping translocation breakpoint protein (JTB) DEAD PF00270.29 EPS28041.1 - 6.3e-17 61.9 0.4 2.7e-16 59.9 0.1 2.2 2 1 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EPS28041.1 - 2.2e-08 34.3 0.0 3.8e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EPS28041.1 - 7.3e-08 32.7 0.0 3.8e-07 30.4 0.0 2.3 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EPS28041.1 - 0.047 14.0 0.6 0.99 9.7 0.1 3.0 2 1 0 2 2 2 0 AAA domain DUF4332 PF14229.6 EPS28041.1 - 0.058 13.6 0.0 0.19 12.0 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) Vps8 PF12816.7 EPS28043.1 - 6.7e-63 211.8 0.0 1.6e-62 210.5 0.0 1.7 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 EPS28043.1 - 1.2e-05 25.2 0.0 0.095 12.6 0.0 3.3 2 0 0 2 2 2 2 Region in Clathrin and VPS zf-C3H2C3 PF17122.5 EPS28043.1 - 0.00015 21.7 0.5 0.00015 21.7 0.5 2.7 2 0 0 2 2 2 1 Zinc-finger Pox_D3 PF04580.13 EPS28043.1 - 0.0045 16.7 0.0 0.0081 15.8 0.0 1.3 1 0 0 1 1 1 1 Chordopoxvirinae D3 protein zf-C3HC4_2 PF13923.6 EPS28043.1 - 0.056 13.3 0.5 0.2 11.5 0.0 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EPS28043.1 - 0.1 12.4 2.3 0.082 12.7 0.2 2.0 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_5 PF14634.6 EPS28043.1 - 0.49 10.4 2.8 0.37 10.8 0.3 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-rbx1 PF12678.7 EPS28043.1 - 8.6 6.7 7.9 0.26 11.6 0.1 2.4 3 0 0 3 3 3 0 RING-H2 zinc finger domain Glyco_hydro_16 PF00722.21 EPS28044.1 - 5.7e-09 35.7 0.1 2e-08 33.9 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_transf_90 PF05686.12 EPS28045.1 - 4.8e-12 45.5 0.1 0.00013 21.0 0.0 3.4 3 1 0 3 3 3 3 Glycosyl transferase family 90 Osw5 PF17062.5 EPS28045.1 - 0.16 12.1 1.7 0.51 10.5 1.7 1.8 1 0 0 1 1 1 0 Outer spore wall 5 GNAT_acetyltr_2 PF13718.6 EPS28046.1 - 7.6e-98 326.4 0.0 1.4e-97 325.6 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 EPS28046.1 - 2e-94 315.7 0.0 3.3e-94 315.0 0.0 1.4 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 EPS28046.1 - 3.1e-66 222.6 0.0 1.6e-65 220.3 0.0 2.1 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 EPS28046.1 - 2.7e-34 117.0 0.0 7e-34 115.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) AAA_30 PF13604.6 EPS28046.1 - 0.00026 20.7 0.0 0.038 13.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EPS28046.1 - 0.02 15.2 0.0 0.066 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain Acetyltransf_1 PF00583.25 EPS28046.1 - 0.091 13.0 0.0 0.54 10.5 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family PAC3 PF10178.9 EPS28046.1 - 0.17 12.1 0.0 0.51 10.5 0.0 1.8 1 0 0 1 1 1 0 Proteasome assembly chaperone 3 Thioredoxin PF00085.20 EPS28047.1 - 1.3e-33 115.1 0.4 3.9e-26 91.0 0.1 2.4 2 0 0 2 2 2 2 Thioredoxin OST3_OST6 PF04756.13 EPS28047.1 - 2.7e-08 33.5 0.1 3.5e-06 26.6 0.0 2.1 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EPS28047.1 - 3.5e-08 33.8 1.1 0.0024 18.3 0.1 2.4 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EPS28047.1 - 0.00013 22.2 0.0 0.09 13.1 0.0 3.2 3 1 0 3 3 3 1 Thioredoxin-like Thioredoxin_6 PF13848.6 EPS28047.1 - 0.00036 20.5 0.0 0.0029 17.5 0.0 2.3 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EPS28047.1 - 0.0069 16.5 0.0 0.018 15.2 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 EPS28047.1 - 0.01 15.8 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family QSOX_Trx1 PF18108.1 EPS28047.1 - 0.055 13.7 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 QSOX Trx-like domain Thioredoxin_3 PF13192.6 EPS28047.1 - 0.078 13.0 0.4 4.2 7.5 0.2 2.4 2 0 0 2 2 2 0 Thioredoxin domain TraF PF13728.6 EPS28047.1 - 0.15 11.9 0.0 0.15 11.9 0.0 3.2 4 0 0 4 4 4 0 F plasmid transfer operon protein ATP-synt PF00231.19 EPS28048.1 - 2.2e-75 254.0 7.8 2.6e-75 253.7 7.8 1.0 1 0 0 1 1 1 1 ATP synthase Topoisom_I_N PF02919.15 EPS28049.1 - 3.6e-97 324.0 3.3 3.6e-97 324.0 3.3 3.6 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 EPS28049.1 - 9e-96 319.6 7.1 9e-96 319.6 7.1 2.2 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.6 EPS28049.1 - 6.7e-32 109.2 0.6 6.7e-32 109.2 0.6 2.4 2 0 0 2 2 2 1 C-terminal topoisomerase domain Epimerase PF01370.21 EPS28050.1 - 1.1e-19 70.9 0.0 2e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EPS28050.1 - 2.6e-09 36.5 0.0 1.2e-08 34.3 0.0 2.0 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EPS28050.1 - 7e-06 25.3 0.0 1.1e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EPS28050.1 - 0.00079 18.9 0.0 0.003 17.0 0.0 1.9 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 EPS28050.1 - 0.013 15.0 0.0 0.023 14.1 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.10 EPS28050.1 - 0.014 15.3 0.0 0.053 13.4 0.0 1.9 2 0 0 2 2 2 0 KR domain Ldh_1_N PF00056.23 EPS28050.1 - 0.041 14.0 0.0 0.089 12.9 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 EPS28050.1 - 0.066 13.5 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Dopey_N PF04118.14 EPS28051.1 - 0.096 11.8 0.3 0.15 11.2 0.3 1.2 1 0 0 1 1 1 0 Dopey, N-terminal ESR1_C PF12743.7 EPS28051.1 - 0.1 12.4 1.5 1.5 8.7 0.1 2.7 2 0 0 2 2 2 0 Oestrogen-type nuclear receptor final C-terminal Vta1 PF04652.16 EPS28052.1 - 6.1e-52 175.4 1.9 9.1e-52 174.9 1.9 1.3 1 0 0 1 1 1 1 Vta1 like Vta1_C PF18097.1 EPS28052.1 - 1.3e-16 60.0 0.1 2.9e-16 58.9 0.1 1.6 1 0 0 1 1 1 1 Vta1 C-terminal domain Peptidase_C2 PF00648.21 EPS28053.1 - 6e-27 94.4 0.0 2.3e-26 92.5 0.0 1.9 1 1 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 EPS28053.1 - 9.6e-06 25.9 0.0 0.0021 18.3 0.0 3.6 3 1 0 3 3 3 1 Calpain large subunit, domain III Mito_carr PF00153.27 EPS28054.1 - 2.7e-55 184.3 1.2 4.1e-20 71.5 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein IncD PF17628.2 EPS28054.1 - 0.03 14.1 0.3 0.086 12.6 0.0 1.8 2 0 0 2 2 2 0 Inclusion membrane protein D SNase PF00565.17 EPS28055.1 - 4.8e-21 75.3 0.1 6.8e-21 74.8 0.1 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue ADK PF00406.22 EPS28056.1 - 3.8e-35 121.2 0.0 3.5e-19 69.4 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.14 EPS28056.1 - 6.6e-14 51.6 0.0 1.1e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.6 EPS28056.1 - 9.6e-14 52.0 0.0 2.7e-09 37.6 0.0 2.5 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 EPS28056.1 - 0.00046 20.7 0.0 0.0048 17.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EPS28056.1 - 0.0031 17.7 0.0 0.032 14.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EPS28056.1 - 0.11 12.7 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EPS28056.1 - 0.15 12.3 0.1 0.5 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EPS28056.1 - 0.15 12.1 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF3446 PF11928.8 EPS28056.1 - 3 8.2 24.0 5.6 7.4 23.4 1.8 1 1 0 1 1 1 0 Early growth response N-terminal domain DNA_primase_lrg PF04104.14 EPS28057.1 - 2.1e-87 292.9 0.0 2.9e-87 292.5 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Sec23_trunk PF04811.15 EPS28058.1 - 7.3e-80 268.0 0.0 1e-79 267.5 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EPS28058.1 - 1.7e-29 102.4 0.0 3.4e-29 101.4 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 EPS28058.1 - 1.9e-24 85.4 0.0 5.2e-24 84.1 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 EPS28058.1 - 1.9e-15 56.6 3.4 3.6e-15 55.7 3.4 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EPS28058.1 - 2.7e-12 46.4 0.0 6.4e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 EPS28058.1 - 0.0086 15.5 1.3 0.014 14.8 0.2 1.8 2 0 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain Ribosomal_L11_N PF03946.14 EPS28059.1 - 2.3e-24 85.0 0.1 3.8e-24 84.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EPS28059.1 - 2.2e-15 56.9 0.2 3.2e-15 56.4 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Glyco_transf_41 PF13844.6 EPS28061.1 - 9.2e-104 347.5 0.0 4.5e-53 180.3 0.0 3.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_1 PF00515.28 EPS28061.1 - 6.6e-17 60.5 10.8 1.8e-05 24.4 0.1 6.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.6 EPS28061.1 - 4.2e-15 55.1 11.8 1.9e-05 24.2 0.3 6.1 3 2 3 6 6 6 3 TPR repeat TPR_8 PF13181.6 EPS28061.1 - 6.3e-14 50.9 4.6 0.00032 20.7 0.1 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EPS28061.1 - 7e-14 50.7 13.6 0.0027 17.7 0.1 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 EPS28061.1 - 2.5e-10 40.0 4.7 0.042 14.2 0.2 5.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 EPS28061.1 - 1.3e-09 38.5 7.7 8.9e-05 22.9 1.7 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 EPS28061.1 - 2.5e-08 34.0 11.2 0.0074 17.0 0.1 6.0 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 EPS28061.1 - 5.1e-08 32.5 14.9 0.0076 16.1 0.1 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 EPS28061.1 - 1.1e-07 32.1 9.9 0.0015 18.8 1.1 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 EPS28061.1 - 1.3e-07 32.1 15.3 0.0035 18.0 0.4 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 EPS28061.1 - 8.6e-06 25.4 6.6 0.23 11.6 0.0 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat BTAD PF03704.17 EPS28061.1 - 0.0016 18.9 2.4 0.15 12.5 0.0 3.1 3 0 0 3 3 3 1 Bacterial transcriptional activator domain TPR_15 PF13429.6 EPS28061.1 - 0.0016 17.7 2.2 0.033 13.4 0.1 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EPS28061.1 - 0.0052 17.0 1.3 0.029 14.6 0.1 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EPS28061.1 - 0.013 15.6 7.6 0.025 14.7 0.1 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.31 EPS28062.1 - 1.7e-27 95.3 2.3 2.4e-16 59.6 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EPS28062.1 - 1.2e-19 70.3 3.1 1.6e-15 57.1 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain DUF2774 PF11242.8 EPS28062.1 - 0.015 15.5 0.0 0.046 13.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) Myb_DNA-bind_4 PF13837.6 EPS28062.1 - 0.067 13.6 1.4 0.21 12.0 0.2 2.3 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain HTH_23 PF13384.6 EPS28062.1 - 0.16 11.8 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain Glyco_hydro_31 PF01055.26 EPS28064.1 - 1.1e-108 364.3 3.4 1.4e-108 363.9 3.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4968 PF16338.5 EPS28064.1 - 7e-05 23.1 0.0 0.00012 22.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) Gal_mutarotas_2 PF13802.6 EPS28064.1 - 0.00019 21.7 1.0 0.0017 18.7 0.2 2.9 2 1 0 2 2 2 1 Galactose mutarotase-like TetR_C_11 PF16859.5 EPS28064.1 - 0.09 13.1 0.0 0.2 12.0 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain NCBP3 PF10309.9 EPS28065.1 - 4.1e-23 81.0 0.1 6.3e-23 80.4 0.1 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 ANAPC4_WD40 PF12894.7 EPS28066.1 - 0.006 16.9 0.0 0.019 15.3 0.0 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EPS28066.1 - 1.2 10.1 5.8 16 6.6 0.1 4.2 4 0 0 4 4 4 0 WD domain, G-beta repeat Ribosomal_L29e PF01779.17 EPS28067.1 - 2.6e-21 75.7 8.9 4.5e-21 74.9 8.9 1.4 1 0 0 1 1 1 1 Ribosomal L29e protein family ATP-synt_DE_N PF02823.16 EPS28068.1 - 1.4e-17 63.3 0.1 2.1e-17 62.8 0.1 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Med25_NR-box PF11244.8 EPS28069.1 - 0.18 12.2 1.9 2.9 8.3 0.2 2.5 1 1 0 2 2 2 0 Mediator complex subunit 25 C-terminal NR box-containing Tetraspanin PF00335.20 EPS28071.1 - 0.0066 16.2 0.0 3 7.5 0.2 2.4 2 0 0 2 2 2 2 Tetraspanin family Cytochrom_B561 PF03188.16 EPS28071.1 - 0.011 15.9 9.0 0.026 14.6 9.0 1.7 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 MAP7 PF05672.11 EPS28071.1 - 7.9 6.1 36.5 0.054 13.2 4.8 3.6 4 0 0 4 4 4 0 MAP7 (E-MAP-115) family PQ-loop PF04193.14 EPS28072.1 - 2.5e-26 91.2 20.5 9e-17 60.6 1.6 3.4 3 0 0 3 3 3 2 PQ loop repeat MatE PF01554.18 EPS28072.1 - 0.015 14.9 0.8 0.03 14.0 0.8 1.6 1 0 0 1 1 1 0 MatE DUF5360 PF17314.2 EPS28072.1 - 0.43 10.7 10.3 0.5 10.4 3.4 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5360) FOXP-CC PF16159.5 EPS28074.1 - 0.011 16.4 3.8 0.05 14.2 0.0 2.7 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-C2H2 PF00096.26 EPS28074.1 - 0.031 14.7 8.4 0.034 14.6 0.1 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPS28074.1 - 0.072 14.0 9.8 0.32 12.0 0.1 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger NRho PF16733.5 EPS28075.1 - 0.1 12.7 0.0 0.93 9.6 0.0 2.2 2 0 0 2 2 2 0 Rhomboid N-terminal domain zf-C2H2 PF00096.26 EPS28077.1 - 7.9e-07 29.2 13.8 0.0062 16.9 2.0 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EPS28077.1 - 1.1e-05 25.7 7.9 0.8 10.2 0.2 4.4 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EPS28077.1 - 0.23 12.4 16.1 0.13 13.2 1.8 4.3 4 1 0 4 4 4 0 C2H2-type zinc finger zf-Di19 PF05605.12 EPS28077.1 - 0.66 10.3 7.4 0.34 11.2 1.1 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding GREB1 PF15782.5 EPS28077.1 - 0.82 6.7 1.6 1 6.4 1.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer dUTPase PF00692.19 EPS28080.1 - 4.7e-43 146.0 0.0 6.5e-43 145.5 0.0 1.1 1 0 0 1 1 1 1 dUTPase DCD PF06559.11 EPS28080.1 - 0.043 12.6 0.0 0.06 12.1 0.0 1.1 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) Phos_pyr_kin PF08543.12 EPS28081.1 - 1.1e-10 41.3 0.0 2.5e-10 40.2 0.0 1.5 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EPS28081.1 - 2.4e-05 23.8 1.6 3.8e-05 23.1 0.0 2.1 2 0 0 2 2 2 1 pfkB family carbohydrate kinase Mago-bind PF09282.10 EPS28081.1 - 0.73 9.8 1.8 2 8.3 1.8 1.7 1 0 0 1 1 1 0 Mago binding Afi1 PF07792.12 EPS28083.1 - 6.4e-46 156.1 0.4 1.4e-45 155.1 0.4 1.6 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.10 EPS28083.1 - 2.3e-38 130.6 0.0 3.7e-38 130.0 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 EPS28083.1 - 7.6e-09 34.7 0.0 0.0025 16.6 0.0 3.8 3 1 0 4 4 4 2 Transport protein Avl9 DUF2347 PF09804.9 EPS28083.1 - 0.029 14.0 0.0 0.1 12.1 0.0 1.9 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) DUF1168 PF06658.12 EPS28083.1 - 0.82 9.5 8.0 0.088 12.6 2.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) EF-hand_6 PF13405.6 EPS28084.1 - 5.4e-12 44.6 3.3 4.2e-05 23.1 0.1 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 EPS28084.1 - 9.5e-12 45.2 2.5 8e-09 35.8 0.8 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EPS28084.1 - 3.7e-11 41.7 3.2 4.2e-05 22.8 0.3 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EPS28084.1 - 4.5e-07 29.6 0.0 0.015 15.1 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EPS28084.1 - 5.6e-06 25.6 5.9 0.012 15.1 0.5 2.4 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 EPS28084.1 - 0.015 15.6 0.0 0.69 10.3 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain RabGAP-TBC PF00566.18 EPS28085.1 - 1.7e-27 96.5 0.0 2.5e-23 82.9 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain RRM_1 PF00076.22 EPS28086.1 - 1.9e-10 40.4 0.0 2.8e-07 30.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zinc_ribbon_9 PF14369.6 EPS28089.1 - 0.0024 18.1 1.7 0.04 14.2 0.4 2.3 2 0 0 2 2 2 1 zinc-ribbon HalOD2 PF18547.1 EPS28089.1 - 0.015 15.2 0.9 0.03 14.2 0.9 1.5 1 1 0 1 1 1 0 Halobacterial output domain 2 Zn_ribbon_SprT PF17283.2 EPS28089.1 - 0.037 13.9 5.2 3.3 7.7 6.8 2.1 1 1 1 2 2 2 0 SprT-like zinc ribbon domain E7 PF00527.18 EPS28089.1 - 0.046 13.9 1.1 0.27 11.5 1.4 1.9 1 1 1 2 2 2 0 E7 protein, Early protein zf_UBZ PF18439.1 EPS28089.1 - 0.073 12.7 1.9 1.4 8.5 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Yippee-Mis18 PF03226.14 EPS28089.1 - 0.17 12.1 3.7 4.4 7.6 3.7 2.0 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Glucosamine_iso PF01182.20 EPS28090.1 - 2.8e-68 230.1 0.0 3.3e-68 230.0 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DNA_pack_N PF02500.15 EPS28091.1 - 0.12 12.2 0.2 0.2 11.4 0.2 1.3 1 0 0 1 1 1 0 Probable DNA packing protein, N-terminus WD40 PF00400.32 EPS28092.1 - 2.2e-21 75.7 9.7 8.7e-06 26.4 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS28092.1 - 8.3e-05 22.8 0.0 0.031 14.6 0.0 3.7 2 2 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain DNA_pol_phi PF04931.13 EPS28092.1 - 2.1 6.4 15.7 3.2 5.7 15.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi SET PF00856.28 EPS28093.1 - 8e-09 36.1 0.0 3.9e-08 33.8 0.0 2.2 2 1 0 2 2 2 1 SET domain TPR_9 PF13371.6 EPS28093.1 - 0.0067 16.5 0.6 0.017 15.2 0.6 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat Phage_XkdX PF09693.10 EPS28093.1 - 0.17 11.9 1.2 0.43 10.7 1.2 1.6 1 0 0 1 1 1 0 Phage uncharacterised protein (Phage_XkdX) zf-MYND PF01753.18 EPS28093.1 - 6.8 6.9 11.4 0.2 11.8 4.6 2.0 2 0 0 2 2 2 0 MYND finger MA3 PF02847.17 EPS28094.1 - 4.6e-29 100.7 0.0 1.1e-28 99.4 0.0 1.7 1 0 0 1 1 1 1 MA3 domain DPM2 PF07297.12 EPS28095.1 - 1.9e-31 108.1 0.8 2.2e-31 108.0 0.8 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 EPS28095.1 - 0.00038 20.3 0.6 0.00047 20.1 0.6 1.1 1 0 0 1 1 1 1 PIG-P COX14 PF14880.6 EPS28095.1 - 0.011 15.6 1.3 0.07 13.0 0.0 2.0 2 0 0 2 2 2 0 Cytochrome oxidase c assembly DUF4229 PF14012.6 EPS28095.1 - 0.019 15.1 1.7 0.027 14.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) DUF1772 PF08592.11 EPS28095.1 - 0.029 14.7 1.0 0.031 14.6 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) LapA_dom PF06305.11 EPS28095.1 - 0.15 11.9 0.1 0.15 11.9 0.1 1.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Trypan_PARP PF05887.11 EPS28096.1 - 1.8 8.6 12.9 6.5 6.7 12.9 2.0 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) HD PF01966.22 EPS28097.1 - 1.2e-06 28.8 0.2 7.1e-06 26.3 0.1 2.2 2 1 0 2 2 2 1 HD domain PDEase_I PF00233.19 EPS28097.1 - 0.095 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase SpoIIIAH PF12685.7 EPS28098.1 - 0.15 11.9 7.0 0.22 11.3 7.0 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Menin PF05053.13 EPS28098.1 - 0.47 8.7 13.3 0.55 8.5 13.3 1.1 1 0 0 1 1 1 0 Menin PAP1 PF08601.10 EPS28098.1 - 5.8 6.5 21.9 5.4 6.6 20.9 1.3 1 1 0 1 1 1 0 Transcription factor PAP1 ResIII PF04851.15 EPS28099.1 - 2.8e-20 73.0 0.0 5.9e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EPS28099.1 - 7.6e-20 71.3 0.1 3e-19 69.4 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EPS28099.1 - 3.9e-16 59.3 0.0 9.8e-16 58.0 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EPS28099.1 - 0.0054 16.4 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 EPS28099.1 - 0.068 13.5 0.0 0.24 11.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain F_actin_cap_B PF01115.17 EPS28100.1 - 1.1e-106 355.8 0.0 1.3e-106 355.6 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Med11 PF10280.9 EPS28101.1 - 2.7e-41 141.2 0.0 3.4e-41 140.9 0.0 1.1 1 0 0 1 1 1 1 Mediator complex protein Med29 PF11568.8 EPS28101.1 - 0.11 12.7 0.0 0.19 12.0 0.0 1.4 1 1 0 1 1 1 0 Mediator complex subunit 29 WD40 PF00400.32 EPS28102.1 - 1.3e-45 152.5 18.6 2.3e-08 34.6 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 EPS28102.1 - 3e-40 137.5 0.1 4.4e-40 136.9 0.1 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 EPS28102.1 - 1.5e-11 44.4 0.2 0.035 14.4 0.1 5.2 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 EPS28102.1 - 5.7e-07 29.3 0.0 1.1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 LisH Nup160 PF11715.8 EPS28102.1 - 2.4e-06 26.5 0.6 0.018 13.7 0.1 3.1 3 0 0 3 3 3 2 Nucleoporin Nup120/160 DUF4550 PF15084.6 EPS28102.1 - 0.022 15.2 0.0 0.086 13.3 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4550) Nbas_N PF15492.6 EPS28102.1 - 0.037 13.3 0.6 1.6 8.0 0.2 2.5 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 EPS28102.1 - 0.05 12.6 0.3 11 4.8 0.0 3.4 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EPS28102.1 - 0.053 13.4 0.7 0.22 11.4 0.0 2.3 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A PALB2_WD40 PF16756.5 EPS28102.1 - 0.7 8.8 2.5 0.54 9.1 0.6 1.8 3 0 0 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Abhydrolase_6 PF12697.7 EPS28103.1 - 4.6e-22 79.7 0.9 7.6e-22 79.0 0.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EPS28103.1 - 1.1e-07 31.8 0.0 2.1e-07 30.9 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EPS28103.1 - 0.00081 18.7 0.1 0.0031 16.8 0.1 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 EPS28103.1 - 0.083 11.8 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Thioesterase PF00975.20 EPS28103.1 - 0.093 12.8 0.0 9.2 6.3 0.0 2.4 2 0 0 2 2 2 0 Thioesterase domain Abhydrolase_5 PF12695.7 EPS28103.1 - 0.14 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Cutinase PF01083.22 EPS28103.1 - 0.18 11.7 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Cutinase Pkinase PF00069.25 EPS28104.1 - 5.8e-12 45.5 0.0 1.9e-07 30.7 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain DUF2417 PF10329.9 EPS28105.1 - 9.1e-82 274.0 0.3 1.3e-81 273.5 0.3 1.1 1 0 0 1 1 1 1 Region of unknown function (DUF2417) NPL4 PF05021.15 EPS28106.1 - 5.6e-136 452.9 0.0 6.9e-136 452.6 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 EPS28106.1 - 5.4e-70 234.2 0.3 8.5e-70 233.5 0.3 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 EPS28106.1 - 0.0088 16.5 0.0 0.051 14.1 0.0 2.2 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 FMN_red PF03358.15 EPS28107.1 - 5.7e-07 29.4 0.0 7.7e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EPS28107.1 - 5.7e-07 29.4 0.0 7.3e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 EPS28107.1 - 0.001 19.3 0.1 0.011 16.0 0.1 2.2 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_5 PF12724.7 EPS28107.1 - 0.077 13.2 0.0 0.2 11.9 0.0 1.6 1 1 1 2 2 2 0 Flavodoxin domain zf-CCCH PF00642.24 EPS28108.1 - 2.1e-17 62.5 28.8 5.3e-07 29.4 1.0 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EPS28108.1 - 1.7e-13 51.2 25.0 9.1e-06 26.3 0.7 5.3 1 1 4 5 5 5 5 Torus domain zf_CCCH_4 PF18345.1 EPS28108.1 - 4.7e-13 48.7 30.9 9.2e-05 22.4 2.0 5.2 5 0 0 5 5 5 4 Zinc finger domain zf-CCCH_4 PF18044.1 EPS28108.1 - 2.3e-05 24.1 0.8 2.3e-05 24.1 0.8 4.7 5 0 0 5 5 5 1 CCCH-type zinc finger zf-C3H1 PF10650.9 EPS28108.1 - 0.013 15.2 7.1 0.097 12.4 0.1 3.8 4 0 0 4 4 4 0 Putative zinc-finger domain Glyco_hydro_18 PF00704.28 EPS28109.1 - 1.3e-69 235.4 0.0 1.4e-69 235.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 AidB_N PF18158.1 EPS28110.1 - 6.8e-16 58.6 0.0 1.2e-15 57.7 0.0 1.3 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_1 PF00441.24 EPS28110.1 - 3.7e-14 53.2 0.0 8.7e-14 52.0 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EPS28110.1 - 5.5e-12 45.7 0.0 4e-11 43.0 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EPS28110.1 - 0.0071 16.6 0.1 0.091 13.0 0.0 2.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain DUF3632 PF12311.8 EPS28111.1 - 3.5e-38 131.8 0.1 6.7e-38 130.9 0.1 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3632) Fungal_trans PF04082.18 EPS28112.1 - 9.3e-09 34.7 0.0 1.8e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain GCP_N_terminal PF17681.1 EPS28112.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Gamma tubulin complex component N-terminal ECH_1 PF00378.20 EPS28113.1 - 2.5e-39 135.1 0.9 9.4e-39 133.2 0.9 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EPS28113.1 - 2.8e-20 73.1 0.9 1.6e-19 70.6 0.9 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase PIG-F PF06699.11 EPS28114.1 - 2e-64 217.1 2.4 2.4e-64 216.8 2.4 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Gly-zipper_YMGG PF13441.6 EPS28114.1 - 0.14 11.9 3.6 0.62 9.8 3.6 1.9 1 1 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 EPS28114.1 - 0.31 11.1 6.8 3.1 7.9 0.2 2.2 2 0 0 2 2 2 0 Glycine zipper RhoGAP PF00620.27 EPS28115.1 - 1.3e-38 132.2 0.0 2.1e-38 131.5 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain DUF3678 PF12435.8 EPS28116.1 - 0.67 9.4 0.2 0.67 9.4 0.2 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3678) zf-Tim10_DDP PF02953.15 EPS28117.1 - 6.5e-19 67.3 9.4 9.3e-19 66.8 9.4 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 EPS28117.1 - 0.001 18.8 6.4 0.13 11.9 0.6 2.0 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) YqzH PF14164.6 EPS28117.1 - 0.032 14.3 0.7 0.22 11.6 0.1 2.1 1 1 1 2 2 2 0 YqzH-like protein TAF6_C PF07571.13 EPS28117.1 - 0.12 12.7 0.1 0.16 12.3 0.1 1.4 1 1 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain ADH_N PF08240.12 EPS28118.1 - 7e-25 87.0 1.8 7e-25 87.0 1.8 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPS28118.1 - 3.1e-18 66.0 0.7 3.1e-18 66.0 0.7 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPS28118.1 - 0.0047 18.0 0.0 0.0096 17.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EPS28118.1 - 0.016 14.5 1.4 0.03 13.6 1.4 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain PQQ PF01011.21 EPS28118.1 - 0.022 14.7 0.1 0.057 13.4 0.1 1.6 1 0 0 1 1 1 0 PQQ enzyme repeat Sacchrp_dh_NADP PF03435.18 EPS28118.1 - 0.035 14.4 0.1 0.063 13.5 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_5 PF07994.12 EPS28119.1 - 1.1e-145 485.1 0.0 1.3e-145 484.8 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 EPS28119.1 - 1.8e-45 153.7 0.5 3.5e-45 152.7 0.5 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase PepSY PF03413.19 EPS28119.1 - 0.38 11.4 1.7 1.2 9.7 0.6 2.2 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain zf-MYND PF01753.18 EPS28121.1 - 1.3e-07 31.6 10.4 2.5e-07 30.7 10.4 1.5 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 EPS28121.1 - 0.00035 20.8 5.9 0.00065 19.9 5.9 1.4 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-HIT PF04438.16 EPS28121.1 - 6.2 6.8 6.7 11 6.0 6.7 1.4 1 0 0 1 1 1 0 HIT zinc finger ADH_zinc_N PF00107.26 EPS28122.1 - 2.9e-24 85.5 0.3 4.9e-24 84.8 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPS28122.1 - 5.6e-21 74.5 0.8 9.4e-21 73.8 0.8 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EPS28122.1 - 6.8e-11 43.4 0.3 1.3e-10 42.4 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 EPS28122.1 - 0.00012 21.6 1.7 0.00027 20.4 0.5 2.2 3 1 0 3 3 3 1 short chain dehydrogenase Epimerase PF01370.21 EPS28122.1 - 0.019 14.4 0.2 0.029 13.8 0.2 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glucokinase PF02685.16 EPS28122.1 - 0.033 13.2 0.2 0.054 12.5 0.2 1.3 1 0 0 1 1 1 0 Glucokinase ACP_syn_III_C PF08541.10 EPS28122.1 - 0.047 13.9 0.2 0.13 12.5 0.2 1.6 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal NAD_binding_10 PF13460.6 EPS28122.1 - 0.069 13.0 0.3 0.13 12.1 0.3 1.4 1 0 0 1 1 1 0 NAD(P)H-binding ADH_N_2 PF16884.5 EPS28122.1 - 0.073 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Fer4_6 PF12837.7 EPS28122.1 - 0.096 12.8 0.4 0.19 11.8 0.4 1.5 1 0 0 1 1 1 0 4Fe-4S binding domain Arf PF00025.21 EPS28123.1 - 2e-73 245.5 0.1 2.3e-73 245.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EPS28123.1 - 4.3e-14 52.8 0.0 5.8e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EPS28123.1 - 5.1e-12 45.6 0.0 6.2e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EPS28123.1 - 6.7e-11 42.0 0.0 8e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EPS28123.1 - 7.9e-10 38.4 0.1 1.1e-05 24.9 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EPS28123.1 - 1.3e-08 34.5 0.0 1.8e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EPS28123.1 - 3.5e-06 27.1 0.0 6.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EPS28123.1 - 0.00068 19.2 0.0 0.054 13.0 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EPS28123.1 - 0.0081 15.7 0.5 0.035 13.6 0.5 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B Actin PF00022.19 EPS28124.1 - 1.2e-28 99.9 0.0 3e-18 65.6 0.0 2.5 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.13 EPS28124.1 - 3.5e-06 26.1 0.0 0.0003 19.7 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Actin_micro PF17003.5 EPS28124.1 - 0.0016 17.7 4.8 0.0034 16.6 0.2 2.4 3 0 0 3 3 3 1 Putative actin-like family FtsA PF14450.6 EPS28124.1 - 0.003 18.0 0.0 0.0079 16.6 0.0 1.8 1 0 0 1 1 1 1 Cell division protein FtsA DUF2114 PF09887.9 EPS28124.1 - 0.077 11.5 0.1 0.11 10.9 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2114) FYDLN_acid PF09538.10 EPS28124.1 - 9 7.0 14.4 1 10.1 7.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Paf1 PF03985.13 EPS28125.1 - 1.2e-50 172.8 0.0 2e-50 172.0 0.0 1.4 1 1 0 1 1 1 1 Paf1 DHO_dh PF01180.21 EPS28127.1 - 1e-65 221.9 0.1 5.2e-55 186.7 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase FMN_dh PF01070.18 EPS28127.1 - 0.04 12.9 1.2 0.9 8.5 1.5 2.4 2 1 0 2 2 2 0 FMN-dependent dehydrogenase PcrB PF01884.17 EPS28127.1 - 0.12 11.8 3.3 1.6 8.1 0.0 2.5 3 0 0 3 3 3 0 PcrB family TIM PF00121.18 EPS28128.1 - 1.7e-39 135.6 0.0 2.3e-39 135.2 0.0 1.2 1 0 0 1 1 1 1 Triosephosphate isomerase LacAB_rpiB PF02502.18 EPS28129.1 - 1.5e-41 141.6 0.0 1.7e-41 141.5 0.0 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase URO-D PF01208.17 EPS28129.1 - 0.075 12.2 0.1 0.17 11.0 0.0 1.5 2 0 0 2 2 2 0 Uroporphyrinogen decarboxylase (URO-D) Gly_rich_SFCGS PF14272.6 EPS28129.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Glycine-rich SFCGS U-box PF04564.15 EPS28130.1 - 1.2e-22 79.8 0.0 2.3e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 U-box domain TPR_2 PF07719.17 EPS28130.1 - 2.3e-07 30.4 0.6 0.032 14.4 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EPS28130.1 - 1.4e-06 28.7 0.3 0.03 14.8 0.5 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EPS28130.1 - 1.7e-06 28.6 2.1 0.062 14.0 0.0 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EPS28130.1 - 2.1e-06 27.9 0.2 0.0012 19.1 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EPS28130.1 - 2.5e-06 27.0 0.1 0.00076 19.2 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EPS28130.1 - 0.0033 17.7 0.0 4.6 7.9 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EPS28130.1 - 0.0034 18.1 0.8 0.54 11.2 0.5 3.3 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EPS28130.1 - 0.012 15.6 0.3 0.39 10.9 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 EPS28130.1 - 0.058 14.0 0.1 0.058 14.0 0.1 2.1 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_10 PF13374.6 EPS28130.1 - 0.059 13.3 0.1 0.94 9.4 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-NOSIP PF15906.5 EPS28130.1 - 0.062 13.5 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein CHIP_TPR_N PF18391.1 EPS28130.1 - 0.11 13.3 4.3 0.21 12.4 4.3 1.5 1 0 0 1 1 1 0 CHIP N-terminal tetratricopeptide repeat domain UPF0242 PF06785.11 EPS28130.1 - 0.38 10.8 3.5 0.56 10.3 3.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ACBP PF00887.19 EPS28131.1 - 1.9e-13 50.4 0.3 3.7e-13 49.5 0.3 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein Tyr-DNA_phospho PF06087.12 EPS28132.1 - 1.3e-139 465.8 0.0 1e-111 373.9 0.0 2.0 1 1 1 2 2 2 2 Tyrosyl-DNA phosphodiesterase DIE2_ALG10 PF04922.12 EPS28133.1 - 1.2e-124 416.6 3.2 1.7e-124 416.1 3.2 1.2 1 0 0 1 1 1 1 DIE2/ALG10 family Pex14_N PF04695.13 EPS28133.1 - 0.17 12.5 5.7 0.17 12.5 4.0 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sld5 PF05916.11 EPS28134.1 - 9.8e-36 122.5 0.0 1.7e-35 121.8 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein TFIIE_alpha PF02002.17 EPS28134.1 - 0.15 12.0 0.1 0.24 11.3 0.1 1.2 1 0 0 1 1 1 0 TFIIE alpha subunit CUE PF02845.16 EPS28135.1 - 3.2e-10 39.5 0.0 5.8e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 CUE domain G2BR PF18442.1 EPS28135.1 - 0.012 15.3 10.5 0.023 14.4 10.5 1.4 1 0 0 1 1 1 0 E3 gp78 Ube2g2-binding region (G2BR) Cue1_U7BR PF18499.1 EPS28135.1 - 0.025 14.6 1.8 0.052 13.6 1.8 1.6 1 0 0 1 1 1 0 Ubc7p-binding region of Cue1 SMC_N PF02463.19 EPS28136.1 - 7.6e-64 215.1 28.7 2.4e-61 207.0 28.7 3.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EPS28136.1 - 5.5e-21 75.0 2.2 8e-20 71.3 0.5 2.9 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 EPS28136.1 - 3e-12 47.4 11.0 3e-12 47.4 11.0 6.9 2 2 3 6 6 6 1 AAA domain AAA_21 PF13304.6 EPS28136.1 - 3.9e-10 40.0 5.9 0.00021 21.2 0.2 3.6 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EPS28136.1 - 0.00013 21.7 0.1 0.00032 20.4 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Spc7 PF08317.11 EPS28136.1 - 0.00054 18.9 25.0 0.00054 18.9 25.0 7.0 2 2 5 7 7 7 4 Spc7 kinetochore protein ABC_tran PF00005.27 EPS28136.1 - 0.069 13.7 0.0 0.069 13.7 0.0 5.9 3 2 1 4 4 4 0 ABC transporter SAM_Exu PF18609.1 EPS28136.1 - 0.24 11.5 0.1 0.24 11.5 0.1 4.4 5 0 0 5 5 5 0 Exuperantia SAM-like domain FDX-ACB PF03147.14 EPS28136.1 - 2.8 8.4 8.8 0.85 10.1 1.7 3.8 3 0 0 3 3 3 0 Ferredoxin-fold anticodon binding domain Methyltransf_25 PF13649.6 EPS28137.1 - 5.4e-15 55.9 0.0 1.2e-14 54.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS28137.1 - 5.1e-13 49.5 0.0 1.2e-12 48.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPS28137.1 - 2e-11 43.9 0.0 3e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPS28137.1 - 3.1e-10 40.7 0.0 7.7e-10 39.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPS28137.1 - 7.1e-10 38.6 0.0 1.2e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EPS28137.1 - 1.6e-06 28.1 0.0 2.2e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EPS28137.1 - 0.017 14.6 0.0 0.057 13.0 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain NOT2_3_5 PF04153.18 EPS28138.1 - 2.2e-27 95.7 1.2 5.9e-27 94.3 0.0 2.1 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family ORC6 PF05460.13 EPS28138.1 - 0.9 8.7 7.4 1.5 8.0 7.4 1.4 1 1 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) MRP-L47 PF06984.13 EPS28139.1 - 1.4e-19 70.0 0.1 2.1e-19 69.4 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Clc-like PF07062.12 EPS28139.1 - 0.094 12.2 0.7 0.15 11.5 0.7 1.3 1 0 0 1 1 1 0 Clc-like GDI PF00996.18 EPS28140.1 - 4.5e-186 618.6 0.0 5.1e-186 618.4 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor 4HBT PF03061.22 EPS28141.1 - 1.2e-12 47.9 0.1 2.3e-12 47.1 0.1 1.4 2 0 0 2 2 2 1 Thioesterase superfamily 4HBT_3 PF13622.6 EPS28141.1 - 0.0014 18.9 0.0 0.0017 18.6 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4442 PF14539.6 EPS28141.1 - 0.14 12.3 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) ORC4_C PF14629.6 EPS28142.1 - 6.8e-50 169.5 0.0 1e-49 168.9 0.0 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 EPS28142.1 - 6.6e-15 55.9 0.2 2.2e-14 54.2 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EPS28142.1 - 3.4e-08 34.0 0.0 1.4e-07 32.0 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EPS28142.1 - 6.5e-06 26.2 0.1 2.4e-05 24.3 0.1 2.0 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EPS28142.1 - 1.8e-05 25.1 0.0 3.8e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 EPS28142.1 - 0.00025 20.3 0.1 0.00042 19.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ATPase_2 PF01637.18 EPS28142.1 - 0.00042 20.3 0.0 0.0013 18.7 0.0 1.7 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea KAP_NTPase PF07693.14 EPS28142.1 - 0.0013 18.1 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain AAA_19 PF13245.6 EPS28142.1 - 0.0017 18.7 0.0 0.0031 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EPS28142.1 - 0.0056 16.2 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region ABC_tran PF00005.27 EPS28142.1 - 0.018 15.6 0.0 0.042 14.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter ATP-synt_ab PF00006.25 EPS28142.1 - 0.02 14.5 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.6 EPS28142.1 - 0.026 14.6 0.0 0.14 12.2 0.0 2.2 3 0 0 3 3 2 0 AAA domain NB-ARC PF00931.22 EPS28142.1 - 0.096 11.8 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Rad17 PF03215.15 EPS28142.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain RGS PF00615.19 EPS28146.1 - 9.8e-35 119.4 0.1 2.5e-34 118.1 0.1 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.21 EPS28146.1 - 5e-26 90.6 0.0 4.8e-20 71.4 0.0 3.5 3 0 0 3 3 3 3 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF1304 PF06993.12 EPS28146.1 - 0.078 13.0 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1304) CDC73_C PF05179.14 EPS28149.1 - 7e-56 188.3 0.0 1.2e-55 187.5 0.0 1.4 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal SET PF00856.28 EPS28150.1 - 3.5e-08 34.0 0.1 5.7e-07 30.1 0.0 2.6 2 1 0 2 2 2 1 SET domain PHD PF00628.29 EPS28150.1 - 1.8e-05 24.5 8.2 4e-05 23.4 8.2 1.6 1 0 0 1 1 1 1 PHD-finger DUF4524 PF15025.6 EPS28151.1 - 0.064 13.0 0.0 0.075 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4524) WD40 PF00400.32 EPS28152.1 - 4.8e-16 58.9 10.6 0.0014 19.4 0.3 4.9 4 0 0 4 4 4 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EPS28152.1 - 0.0079 15.2 0.2 6.3 5.7 0.0 3.0 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EPS28152.1 - 0.057 12.1 1.5 0.29 9.7 0.2 2.4 1 1 2 3 3 3 0 Nucleoporin Nup120/160 Glycos_transf_4 PF00953.21 EPS28153.1 - 2.8e-33 115.2 11.9 2.8e-33 115.2 11.9 2.5 3 1 0 3 3 3 1 Glycosyl transferase family 4 DUF4267 PF14087.6 EPS28154.1 - 3.1e-13 49.8 2.9 4.5e-13 49.2 2.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DUF3425 PF11905.8 EPS28155.1 - 1.1e-11 44.8 3.2 1.1e-10 41.5 3.2 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) Aconitase PF00330.20 EPS28156.1 - 1.1e-162 542.2 0.0 1.4e-162 541.9 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EPS28156.1 - 1.7e-38 131.9 0.0 3.4e-38 130.9 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Glyco_transf_5 PF08323.11 EPS28157.1 - 3e-12 46.7 0.2 5.3e-12 46.0 0.2 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Alpha-amylase PF00128.24 EPS28157.1 - 1.9e-08 34.3 1.4 1.9e-08 34.3 1.4 2.8 3 1 0 3 3 3 1 Alpha amylase, catalytic domain Glycos_transf_1 PF00534.20 EPS28157.1 - 0.00059 19.4 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EPS28157.1 - 0.0088 16.1 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Pribosyltran PF00156.27 EPS28158.1 - 2.1e-14 53.3 0.2 3.1e-14 52.8 0.2 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain MTHFR PF02219.17 EPS28159.1 - 7.1e-117 389.8 0.0 1e-116 389.3 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF2418 PF10332.9 EPS28161.1 - 2.2e-33 114.7 1.5 2.6e-33 114.4 0.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) ATP-synt_F PF01990.17 EPS28162.1 - 1.6e-33 114.9 0.1 1.8e-33 114.7 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit E1_DerP2_DerF2 PF02221.15 EPS28164.1 - 4e-28 98.5 0.2 5.1e-28 98.2 0.2 1.1 1 0 0 1 1 1 1 ML domain DUF1091 PF06477.13 EPS28164.1 - 0.092 13.2 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1091) Glyco_hydro_17 PF00332.18 EPS28166.1 - 2.3e-08 34.0 0.9 3.8e-08 33.3 0.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Thiolase_N PF00108.23 EPS28167.1 - 1.6e-63 214.5 0.6 2.4e-63 213.9 0.6 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EPS28167.1 - 6.7e-43 145.3 0.2 1.4e-42 144.2 0.2 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EPS28167.1 - 0.00095 18.8 0.3 0.0042 16.7 0.2 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EPS28167.1 - 0.0063 16.3 0.7 0.26 11.2 0.1 2.4 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.10 EPS28167.1 - 0.085 13.0 0.0 0.31 11.2 0.0 2.0 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal AMP-binding PF00501.28 EPS28168.1 - 2.2e-59 201.1 0.0 2.9e-59 200.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EPS28168.1 - 0.00031 21.7 0.1 0.00082 20.3 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF3918 PF13056.6 EPS28168.1 - 0.041 13.5 0.1 0.093 12.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) DIOX_N PF14226.6 EPS28170.1 - 8.7e-35 120.0 0.0 8.8e-33 113.6 0.0 2.3 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal Abhydrolase_6 PF12697.7 EPS28170.1 - 3.5e-14 53.9 0.0 6.5e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family 2OG-FeII_Oxy PF03171.20 EPS28170.1 - 2.3e-12 47.3 0.0 4.8e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Abhydrolase_1 PF00561.20 EPS28170.1 - 1.2e-09 38.3 0.0 2.1e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EPS28170.1 - 5.3e-09 35.7 0.0 1.4e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EPS28170.1 - 0.00018 21.7 0.0 0.00085 19.5 0.0 1.9 2 0 0 2 2 2 1 Thioesterase domain Lipase_3 PF01764.25 EPS28170.1 - 0.00031 20.6 0.0 0.00081 19.3 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) LIDHydrolase PF10230.9 EPS28170.1 - 0.0022 17.6 0.0 0.0042 16.7 0.0 1.4 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_3 PF07859.13 EPS28170.1 - 0.0098 15.8 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EPS28170.1 - 0.011 15.4 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Putative esterase PGAP1 PF07819.13 EPS28170.1 - 0.017 14.8 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_2 PF02230.16 EPS28170.1 - 0.1 12.4 0.0 0.65 9.8 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase APH PF01636.23 EPS28171.1 - 2e-18 67.2 0.0 6.4e-18 65.5 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 EPS28171.1 - 1.2e-05 24.7 0.2 0.0037 16.5 0.0 2.2 2 0 0 2 2 2 2 Fructosamine kinase ATG22 PF11700.8 EPS28172.1 - 9.2e-134 446.6 27.1 1.1e-133 446.4 27.1 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 EPS28172.1 - 1.1e-09 37.6 34.0 7.9e-05 21.7 10.6 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF2678 PF10856.8 EPS28172.1 - 0.12 12.3 5.6 1.6 8.7 0.9 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2678) VbhA PF18495.1 EPS28172.1 - 0.13 12.2 0.2 0.23 11.3 0.2 1.3 1 0 0 1 1 1 0 Antitoxin VbhA FAD_binding_3 PF01494.19 EPS28173.1 - 3.1e-73 247.0 0.0 4.4e-73 246.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EPS28173.1 - 0.00015 21.5 0.8 0.13 11.8 0.1 3.1 2 2 0 3 3 3 2 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EPS28173.1 - 0.0022 17.3 0.2 0.058 12.7 0.0 2.7 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 EPS28173.1 - 0.02 14.1 0.0 2.3 7.4 0.0 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPS28173.1 - 0.058 13.6 0.0 0.15 12.3 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EPS28173.1 - 0.11 11.7 0.1 5.3 6.2 0.0 2.1 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPS28173.1 - 0.15 12.6 0.0 2.8 8.5 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EPS28173.1 - 0.15 11.1 0.1 0.33 10.0 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain Sugar_tr PF00083.24 EPS28175.1 - 2.4e-129 432.2 18.0 2.7e-129 432.0 18.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS28175.1 - 4.4e-26 91.6 25.6 1.3e-19 70.4 10.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EPS28175.1 - 0.017 13.5 11.6 0.0088 14.5 1.8 2.1 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.7 EPS28175.1 - 0.22 10.3 17.4 0.99 8.2 0.4 3.3 2 2 1 3 3 3 0 MFS_1 like family KH_8 PF17903.1 EPS28176.1 - 2.6e-30 104.3 0.0 6.7e-30 103.0 0.0 1.7 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 EPS28176.1 - 0.011 15.6 0.0 0.034 14.0 0.0 1.9 2 1 0 2 2 2 0 KH domain Methyltransf_23 PF13489.6 EPS28177.1 - 5.4e-11 42.6 0.0 8.4e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPS28177.1 - 6.4e-11 42.8 0.0 2e-10 41.2 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS28177.1 - 1.6e-10 41.5 0.0 3.5e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPS28177.1 - 8.6e-07 29.6 0.0 2.2e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPS28177.1 - 0.00016 21.5 0.0 0.0016 18.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EPS28177.1 - 0.0073 15.6 0.0 0.024 13.9 0.0 1.8 2 0 0 2 2 2 1 O-methyltransferase domain Methyltransf_29 PF03141.16 EPS28177.1 - 0.1 11.2 0.0 0.32 9.5 0.0 1.7 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.18 EPS28177.1 - 0.14 11.5 0.0 0.77 9.0 0.0 2.1 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 EPS28177.1 - 0.16 11.5 0.0 0.89 9.0 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase GCP_N_terminal PF17681.1 EPS28179.1 - 1.8e-66 224.9 0.0 3.7e-66 223.9 0.0 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EPS28179.1 - 4.5e-59 200.4 6.2 7.4e-59 199.7 6.2 1.3 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal CLZ PF16526.5 EPS28179.1 - 7.7 7.0 7.4 1.3 9.4 0.7 3.1 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Proteasome PF00227.26 EPS28180.1 - 1.5e-57 194.1 0.1 1.9e-57 193.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EPS28180.1 - 1.5e-12 47.0 0.2 3.6e-12 45.7 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Fungal_trans PF04082.18 EPS28181.1 - 7.4e-16 58.0 1.6 1.1e-15 57.4 1.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_8 PF05148.15 EPS28182.1 - 1.3e-54 185.4 0.0 1.3e-52 178.9 0.0 2.7 3 0 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 EPS28182.1 - 4.1e-07 30.5 0.0 1.7e-06 28.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPS28182.1 - 3.2e-05 24.5 0.0 0.0013 19.4 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Fungal_trans_2 PF11951.8 EPS28183.1 - 4.6e-18 65.2 0.0 2.1e-16 59.8 0.0 2.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS28183.1 - 2.5e-06 27.5 8.4 5.2e-06 26.5 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BAR_2 PF10455.9 EPS28185.1 - 1e-62 211.9 3.0 1.4e-62 211.4 3.0 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 EPS28185.1 - 3e-22 79.4 8.3 6e-21 75.2 8.3 2.0 1 1 0 1 1 1 1 BAR domain ATP-synt_B PF00430.18 EPS28185.1 - 0.0066 16.5 4.5 0.027 14.6 4.5 2.0 1 0 0 1 1 1 1 ATP synthase B/B' CF(0) BAR_3 PF16746.5 EPS28185.1 - 0.007 16.1 3.9 0.0082 15.9 0.3 2.2 2 1 0 2 2 2 1 BAR domain of APPL family DUF4111 PF13427.6 EPS28185.1 - 0.063 13.5 0.2 0.21 11.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4111) CorA PF01544.18 EPS28185.1 - 0.33 10.2 2.8 9.3 5.5 0.2 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Mt_ATP-synt_B PF05405.14 EPS28185.1 - 0.81 9.3 5.9 6.9 6.3 0.2 2.4 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF4472 PF14739.6 EPS28185.1 - 1.2 9.9 8.2 1.3 9.8 0.6 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4472) ATP_synt_H PF05493.13 EPS28186.1 - 4.2e-24 84.8 3.1 4.7e-24 84.6 3.1 1.0 1 0 0 1 1 1 1 ATP synthase subunit H Git3 PF11710.8 EPS28186.1 - 0.024 14.4 0.3 0.027 14.2 0.3 1.0 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 Pox_A14 PF05767.12 EPS28186.1 - 0.033 14.4 0.8 0.037 14.2 0.8 1.1 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 YfhO PF09586.10 EPS28186.1 - 0.093 11.0 1.2 0.096 10.9 1.2 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF4131 PF13567.6 EPS28186.1 - 0.1 12.2 2.6 0.11 12.2 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) OppC_N PF12911.7 EPS28186.1 - 8.5 6.4 9.7 7e+02 0.3 9.7 2.3 1 1 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Arv1 PF04161.13 EPS28187.1 - 4.7e-60 203.3 0.0 1.3e-50 172.5 0.0 2.2 2 0 0 2 2 2 2 Arv1-like family NAT PF04768.13 EPS28188.1 - 1.5e-51 174.5 0.0 2.1e-50 170.7 0.0 2.1 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Sua5_yciO_yrdC PF01300.18 EPS28188.1 - 0.063 12.8 0.5 0.16 11.5 0.1 1.9 2 0 0 2 2 2 0 Telomere recombination PEP_mutase PF13714.6 EPS28188.1 - 0.069 12.6 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase Acetyltransf_1 PF00583.25 EPS28189.1 - 4.6e-13 49.4 0.0 7.4e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EPS28189.1 - 1e-12 48.1 0.0 1.4e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EPS28189.1 - 9.6e-10 38.8 0.0 1.7e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EPS28189.1 - 0.0031 17.6 0.0 0.0054 16.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPS28189.1 - 0.0059 16.5 0.0 0.0096 15.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 EPS28189.1 - 0.063 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase NOG1_N PF17835.1 EPS28190.1 - 3.4e-49 166.9 1.5 3.9e-49 166.7 0.0 1.9 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOGCT PF08155.11 EPS28190.1 - 3e-28 97.5 1.5 7.7e-28 96.3 1.5 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 EPS28190.1 - 3.8e-26 90.6 0.3 8.9e-26 89.4 0.3 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 EPS28190.1 - 6.1e-16 58.5 0.0 1.4e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EPS28190.1 - 1.8e-07 30.9 0.0 4.3e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EPS28190.1 - 0.0016 18.3 0.5 0.68 9.8 0.1 3.2 3 1 0 3 3 3 1 RsgA GTPase Sigma54_activ_2 PF14532.6 EPS28190.1 - 0.002 18.3 0.0 0.0045 17.1 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain Dynamin_N PF00350.23 EPS28190.1 - 0.0053 16.8 0.0 3.9 7.5 0.0 2.7 1 1 0 2 2 2 2 Dynamin family AAA_16 PF13191.6 EPS28190.1 - 0.085 13.2 2.0 0.2 12.1 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain Sugar_tr PF00083.24 EPS28194.1 - 8.9e-139 463.2 33.1 1e-138 463.0 33.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS28194.1 - 3.5e-25 88.7 59.3 7.3e-22 77.8 32.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.9 EPS28194.1 - 0.03 14.6 1.3 0.03 14.6 1.3 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2530) NAD_binding_2 PF03446.15 EPS28195.1 - 1.4e-30 106.5 0.1 2.1e-30 106.0 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EPS28195.1 - 3.4e-11 43.6 0.1 8.9e-11 42.2 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EPS28195.1 - 2.8e-09 37.2 0.0 6.9e-09 35.9 0.0 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_11 PF14833.6 EPS28195.1 - 4.7e-08 33.3 1.4 2e-07 31.2 0.3 2.5 2 1 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Semialdhyde_dh PF01118.24 EPS28195.1 - 0.0022 18.4 0.0 0.0041 17.6 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain OCD_Mu_crystall PF02423.15 EPS28195.1 - 0.0041 16.1 0.1 0.0061 15.5 0.1 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family IlvN PF07991.12 EPS28195.1 - 0.0055 16.3 0.1 0.026 14.1 0.0 1.9 1 1 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Sacchrp_dh_NADP PF03435.18 EPS28195.1 - 0.012 15.8 0.1 0.028 14.7 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain UDPG_MGDP_dh_N PF03721.14 EPS28195.1 - 0.02 14.5 0.1 0.33 10.5 0.0 2.3 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 EPS28195.1 - 0.068 12.5 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DSBA PF01323.20 EPS28197.1 - 4.6e-17 62.4 0.0 5.6e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain MFS_1 PF07690.16 EPS28198.1 - 8e-40 136.8 42.2 8e-40 136.8 42.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS28198.1 - 9.6e-06 24.7 16.0 9.6e-06 24.7 16.0 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter G0-G1_switch_2 PF15103.6 EPS28198.1 - 0.17 12.3 0.0 0.98 9.9 0.0 2.2 2 0 0 2 2 2 0 G0/G1 switch protein 2 DDRGK PF09756.9 EPS28199.1 - 0.11 12.1 29.9 0.12 12.0 29.9 1.1 1 0 0 1 1 1 0 DDRGK domain PTPRCAP PF15713.5 EPS28199.1 - 0.12 12.7 10.1 0.13 12.6 10.1 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Rrn6 PF10214.9 EPS28199.1 - 0.13 10.7 21.5 0.2 10.1 21.5 1.3 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor NST1 PF13945.6 EPS28199.1 - 0.17 12.0 30.6 0.25 11.5 30.6 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator TFIIF_alpha PF05793.12 EPS28199.1 - 0.31 9.6 27.3 0.31 9.6 27.3 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FAM76 PF16046.5 EPS28199.1 - 0.42 9.9 30.7 0.49 9.7 30.7 1.0 1 0 0 1 1 1 0 FAM76 protein LRIF1 PF15741.5 EPS28199.1 - 0.44 9.0 27.7 0.43 9.1 27.7 1.0 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 PEHE PF15275.6 EPS28199.1 - 0.83 10.3 15.1 1 10.0 15.1 1.2 1 0 0 1 1 1 0 PEHE domain MMR1 PF08505.10 EPS28199.1 - 0.91 9.8 22.7 0.96 9.7 22.7 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF4692 PF15763.5 EPS28199.1 - 1.1 9.7 14.5 1.2 9.6 14.5 1.1 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Vfa1 PF08432.10 EPS28199.1 - 1.2 9.5 29.9 1.3 9.3 29.9 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF3807 PF12720.7 EPS28199.1 - 1.5 9.1 30.4 1.9 8.8 30.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) CDC45 PF02724.14 EPS28199.1 - 1.5 7.0 24.9 1.7 6.8 24.9 1.0 1 0 0 1 1 1 0 CDC45-like protein Tim54 PF11711.8 EPS28199.1 - 1.6 7.4 17.5 1.7 7.4 17.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CPSF100_C PF13299.6 EPS28199.1 - 1.6 8.9 16.2 2.1 8.5 16.2 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Tir_receptor_N PF07490.11 EPS28199.1 - 1.7 8.4 6.7 2 8.2 6.7 1.1 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus SRP-alpha_N PF04086.13 EPS28199.1 - 1.7 8.5 27.4 1.9 8.3 27.4 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal PPL5 PF18168.1 EPS28199.1 - 1.9 7.7 16.4 2 7.6 16.4 1.2 1 0 0 1 1 1 0 Prim-pol family 5 YL1 PF05764.13 EPS28199.1 - 1.9 8.5 37.2 2.1 8.4 37.2 1.0 1 0 0 1 1 1 0 YL1 nuclear protein Connexin PF00029.19 EPS28199.1 - 3 7.6 19.0 3.2 7.5 19.0 1.2 1 0 0 1 1 1 0 Connexin RNA_pol_Rpc4 PF05132.14 EPS28199.1 - 3.7 8.0 18.8 4.5 7.7 18.8 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 RPN2_C PF18004.1 EPS28199.1 - 5.2 7.0 30.9 5.9 6.8 30.9 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain LicD PF04991.13 EPS28199.1 - 8.3 6.5 15.8 9 6.4 15.8 1.2 1 0 0 1 1 1 0 LicD family NPR3 PF03666.13 EPS28199.1 - 8.7 5.0 27.6 9.4 4.9 27.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4746 PF15928.5 EPS28199.1 - 9.2 5.6 13.8 9.1 5.6 13.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF2052 PF09747.9 EPS28199.1 - 9.7 6.3 19.2 10 6.2 19.2 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) GalP_UDP_transf PF01087.22 EPS28201.1 - 8.1e-70 235.0 0.5 1.9e-68 230.5 0.2 2.7 3 0 0 3 3 3 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.17 EPS28201.1 - 4.5e-60 202.2 0.1 1.2e-59 200.8 0.0 1.6 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DUF4921 PF16268.5 EPS28201.1 - 0.00041 19.3 0.0 0.1 11.4 0.0 2.5 2 1 0 2 2 2 2 Domain of unknown function (DUF4921) DcpS_C PF11969.8 EPS28201.1 - 0.15 12.6 0.0 0.36 11.3 0.0 1.6 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding WG_beta_rep PF14903.6 EPS28201.1 - 0.18 12.1 2.1 0.22 11.8 0.1 2.2 3 0 0 3 3 3 0 WG containing repeat DAO PF01266.24 EPS28202.1 - 6.6e-38 131.2 0.2 7.5e-38 131.0 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EPS28202.1 - 0.00074 18.7 0.1 0.0013 17.9 0.0 1.4 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EPS28202.1 - 0.00077 19.6 0.1 0.0021 18.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EPS28202.1 - 0.0032 16.7 0.1 0.015 14.6 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPS28202.1 - 0.0067 17.0 0.1 0.019 15.5 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EPS28202.1 - 0.026 13.8 0.1 0.054 12.7 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 EPS28202.1 - 0.036 13.3 0.0 0.054 12.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF1188 PF06690.11 EPS28202.1 - 0.04 13.5 0.2 4.1 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) NAD_binding_7 PF13241.6 EPS28202.1 - 0.04 14.4 0.0 0.054 13.9 0.0 1.5 1 1 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.20 EPS28202.1 - 0.041 14.0 0.2 0.09 12.8 0.1 1.7 2 0 0 2 2 1 0 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EPS28202.1 - 0.045 14.0 0.2 0.34 11.2 0.0 2.4 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain Glu_dehyd_C PF16912.5 EPS28202.1 - 0.054 13.0 0.0 0.97 8.9 0.0 2.2 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus ApbA PF02558.16 EPS28202.1 - 0.076 12.6 0.3 0.21 11.2 0.1 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 EPS28202.1 - 0.081 12.2 0.9 0.16 11.1 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain DUF1769 PF08588.10 EPS28202.1 - 0.086 13.1 0.1 0.27 11.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) Trp_halogenase PF04820.14 EPS28202.1 - 0.16 10.8 0.3 0.43 9.4 0.1 1.7 2 0 0 2 2 2 0 Tryptophan halogenase Erg28 PF03694.13 EPS28203.1 - 1.8e-35 121.6 0.8 2.2e-35 121.4 0.8 1.1 1 0 0 1 1 1 1 Erg28 like protein adh_short PF00106.25 EPS28204.1 - 2e-36 125.3 0.1 2e-36 125.3 0.1 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS28204.1 - 4.8e-23 81.9 0.0 6.4e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPS28204.1 - 0.00032 20.7 0.1 0.00061 19.7 0.1 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EPS28204.1 - 0.0029 16.8 0.1 0.0039 16.4 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Dicistro_VP4 PF11492.8 EPS28206.1 - 0.00049 20.0 0.8 11 6.1 0.1 4.5 3 1 1 4 4 4 3 Cricket paralysis virus, VP4 CoA_binding_2 PF13380.6 EPS28208.1 - 3.6e-28 98.4 0.0 4.4e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain Rad4 PF03835.15 EPS28209.1 - 9.6e-39 132.4 0.0 2.7e-38 131.0 0.0 1.8 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 EPS28209.1 - 1.3e-28 99.2 0.1 2.4e-28 98.3 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 EPS28209.1 - 3.6e-16 58.7 0.0 7.7e-16 57.7 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 EPS28209.1 - 6.2e-16 59.1 0.2 6.2e-16 59.1 0.2 4.6 5 0 0 5 5 5 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 EPS28209.1 - 0.0071 16.8 0.0 0.019 15.4 0.0 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF3420 PF11900.8 EPS28209.1 - 0.028 14.5 1.0 0.089 12.9 1.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3420) Colicin_Pyocin PF01320.18 EPS28209.1 - 0.06 13.5 0.1 0.15 12.2 0.1 1.7 1 0 0 1 1 1 0 Colicin immunity protein / pyocin immunity protein HAUS6_N PF14661.6 EPS28210.1 - 8.2e-44 149.9 1.0 8.2e-44 149.9 1.0 1.5 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 6 N-terminus HD_3 PF13023.6 EPS28211.1 - 5.1e-49 166.4 0.2 6e-49 166.1 0.2 1.0 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 EPS28211.1 - 1.5e-11 44.3 0.1 2e-11 44.0 0.1 1.1 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HIT PF01230.23 EPS28212.1 - 5.3e-24 84.8 0.1 7.9e-24 84.3 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EPS28212.1 - 1.1e-05 25.9 0.0 1.6e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding GalP_UDP_tr_C PF02744.17 EPS28212.1 - 0.05 13.3 0.0 0.074 12.8 0.0 1.2 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, C-terminal domain Mob1_phocein PF03637.17 EPS28213.1 - 4.9e-26 91.7 0.9 5.5e-26 91.6 0.0 1.4 2 0 0 2 2 2 1 Mob1/phocein family cobW PF02492.19 EPS28214.1 - 8.3e-49 165.5 0.1 1.1e-48 165.1 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 EPS28214.1 - 2.1e-05 24.5 0.1 0.12 12.3 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase CobW_C PF07683.14 EPS28214.1 - 7.6e-05 22.6 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_16 PF13191.6 EPS28214.1 - 0.0009 19.7 0.0 0.0027 18.1 0.0 1.7 2 0 0 2 2 1 1 AAA ATPase domain ATPase_2 PF01637.18 EPS28214.1 - 0.019 14.9 0.0 0.032 14.2 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 EPS28214.1 - 0.023 15.2 0.0 0.039 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 EPS28214.1 - 0.027 14.0 0.7 1.4 8.5 0.0 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EPS28214.1 - 0.037 14.1 0.0 0.083 13.0 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase MeaB PF03308.16 EPS28214.1 - 0.037 13.0 0.6 0.89 8.5 0.0 2.7 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_29 PF13555.6 EPS28214.1 - 0.041 13.6 0.1 0.17 11.6 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain T2SSE PF00437.20 EPS28214.1 - 0.057 12.5 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein TsaE PF02367.17 EPS28214.1 - 0.07 13.1 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 EPS28214.1 - 0.094 13.0 0.2 0.28 11.4 0.0 1.8 3 0 0 3 3 2 0 AAA domain ABC_tran PF00005.27 EPS28214.1 - 0.1 13.1 0.1 0.43 11.1 0.1 2.0 2 0 0 2 2 2 0 ABC transporter ATP_bind_1 PF03029.17 EPS28214.1 - 0.15 11.8 0.2 3.3 7.4 0.1 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.6 EPS28214.1 - 0.15 12.1 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EPS28214.1 - 0.17 12.5 0.2 0.64 10.6 0.1 2.0 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 EPS28214.1 - 0.17 11.8 0.4 0.42 10.5 0.4 1.7 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Septin PF00735.18 EPS28214.1 - 0.18 11.0 0.3 7.9 5.7 0.0 2.1 2 0 0 2 2 2 0 Septin Pkinase PF00069.25 EPS28215.1 - 3.8e-12 46.1 0.0 7e-11 42.0 0.0 2.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS28215.1 - 8.6e-11 41.6 0.0 1.2e-09 37.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Lon_C PF05362.13 EPS28216.1 - 1.2e-64 217.6 0.0 2.2e-64 216.8 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 EPS28216.1 - 7.2e-32 111.0 0.0 1.6e-31 109.8 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 EPS28216.1 - 7.6e-22 78.1 0.0 1.7e-21 77.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EPS28216.1 - 2.8e-07 30.6 0.0 5.7e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 EPS28216.1 - 1.5e-06 28.1 0.0 3.9e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.14 EPS28216.1 - 3.6e-06 27.2 0.1 1.2e-05 25.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EPS28216.1 - 6.1e-06 26.6 0.1 8.3e-05 22.9 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.11 EPS28216.1 - 1.4e-05 24.2 0.2 3.1e-05 23.1 0.0 1.6 2 0 0 2 2 2 1 PrkA AAA domain AAA_16 PF13191.6 EPS28216.1 - 0.00017 22.0 1.9 0.00067 20.1 0.1 2.7 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 EPS28216.1 - 0.00027 20.7 0.0 0.00097 18.9 0.0 1.9 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EPS28216.1 - 0.0072 16.9 1.0 0.041 14.4 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_14 PF13173.6 EPS28216.1 - 0.0079 16.2 0.0 0.018 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EPS28216.1 - 0.025 14.3 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EPS28216.1 - 0.04 13.8 0.2 0.47 10.3 0.0 2.6 1 1 1 2 2 2 0 NTPase DUF4276 PF14103.6 EPS28216.1 - 0.042 14.1 0.3 0.042 14.1 0.3 2.3 2 0 0 2 2 1 0 Domain of unknown function (DUF4276) IstB_IS21 PF01695.17 EPS28216.1 - 0.045 13.5 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein DNTTIP1_dimer PF18192.1 EPS28216.1 - 0.14 12.5 2.0 2.7 8.4 0.5 3.0 2 1 0 2 2 2 0 DNTTIP1 dimerisation domain RsgA_GTPase PF03193.16 EPS28216.1 - 0.15 12.0 0.0 0.4 10.6 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 EPS28216.1 - 0.15 11.6 0.5 0.31 10.5 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_helicase PF00910.22 EPS28216.1 - 0.17 12.3 0.0 0.47 10.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase DUF4551 PF15087.6 EPS28216.1 - 9.6 4.9 11.2 16 4.2 11.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DnaJ_C PF01556.18 EPS28217.1 - 1.7e-36 125.5 0.0 2.4e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EPS28217.1 - 8.6e-23 80.2 3.1 1.5e-22 79.5 3.1 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EPS28217.1 - 1.9e-09 37.8 19.0 4e-09 36.7 19.0 1.6 1 0 0 1 1 1 1 DnaJ central domain Cytochrome_C7 PF14522.6 EPS28217.1 - 0.3 11.1 7.3 1 9.4 0.5 2.7 2 1 0 2 2 2 0 Cytochrome c7 and related cytochrome c Anti-TRAP PF15777.5 EPS28217.1 - 0.85 9.6 15.2 0.12 12.3 1.5 3.1 2 1 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EPS28217.1 - 4.8 7.2 7.6 11 6.1 1.3 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA BRO1 PF03097.18 EPS28218.1 - 4.5e-131 437.2 6.3 4.5e-131 437.2 6.3 2.0 2 1 1 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EPS28218.1 - 1e-81 274.5 18.5 1.8e-81 273.7 18.5 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF416 PF04222.12 EPS28218.1 - 0.0047 16.4 3.3 1.4 8.3 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF416) DUF2383 PF09537.10 EPS28218.1 - 0.017 15.5 4.6 0.47 10.8 0.1 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF2383) DUF1664 PF07889.12 EPS28218.1 - 2.9 8.0 8.0 9.4 6.3 0.8 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 EPS28218.1 - 7 7.0 9.4 0.76 10.1 1.2 3.4 3 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 adh_short PF00106.25 EPS28219.1 - 2.2e-10 40.3 0.0 2.4e-06 27.2 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 EPS28219.1 - 2.1e-06 27.8 0.0 3.1e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EPS28219.1 - 0.031 14.2 0.0 0.29 11.0 0.0 2.4 3 0 0 3 3 3 0 NAD(P)H-binding NAD_binding_4 PF07993.12 EPS28219.1 - 0.062 12.5 0.0 0.089 11.9 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein SAP30_Sin3_bdg PF13867.6 EPS28220.1 - 6.4e-10 39.2 0.3 6.2e-09 36.1 0.0 2.2 2 0 0 2 2 2 1 Sin3 binding region of histone deacetylase complex subunit SAP30 zf-H2C2_2 PF13465.6 EPS28222.1 - 4.1e-08 33.3 18.8 5.9e-05 23.3 3.3 4.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.26 EPS28222.1 - 5.4e-08 32.9 17.1 0.00078 19.8 4.5 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPS28222.1 - 0.0019 18.9 15.8 0.055 14.3 3.0 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EPS28222.1 - 0.041 14.2 1.4 0.12 12.6 0.2 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 EPS28222.1 - 0.056 14.1 1.9 0.16 12.6 0.2 2.5 1 1 1 2 2 2 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 EPS28222.1 - 0.12 12.4 0.8 9.3 6.4 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EPS28223.1 - 1.1 9.8 5.6 0.54 10.8 1.9 2.2 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 EPS28223.1 - 2 9.5 5.8 18 6.5 0.8 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger LSM PF01423.22 EPS28224.1 - 2.9e-15 55.7 0.1 4.7e-15 55.0 0.1 1.3 1 0 0 1 1 1 1 LSM domain NUC173 PF08161.12 EPS28225.1 - 3.2e-80 268.6 0.1 1.1e-77 260.4 0.0 2.9 3 0 0 3 3 3 2 NUC173 domain HEAT_2 PF13646.6 EPS28225.1 - 0.074 13.4 0.1 0.73 10.3 0.1 2.8 1 0 0 1 1 1 0 HEAT repeats HEAT PF02985.22 EPS28225.1 - 0.12 12.7 0.2 21 5.7 0.0 3.9 3 0 0 3 3 3 0 HEAT repeat TPR_1 PF00515.28 EPS28231.1 - 5.5e-51 168.4 25.8 5.7e-08 32.2 0.1 11.3 10 2 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.17 EPS28231.1 - 1e-46 153.3 17.3 1.4e-05 24.8 0.0 10.9 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_8 PF13181.6 EPS28231.1 - 4.3e-38 126.3 17.0 9e-06 25.5 0.0 10.8 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_14 PF13428.6 EPS28231.1 - 6.6e-26 88.8 8.7 4.1e-05 24.0 0.1 8.8 4 3 6 10 10 10 7 Tetratricopeptide repeat TPR_17 PF13431.6 EPS28231.1 - 7.4e-26 88.6 17.1 0.00013 22.1 0.1 9.4 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_19 PF14559.6 EPS28231.1 - 5e-25 87.8 10.9 0.00029 21.3 0.1 7.3 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 EPS28231.1 - 2.1e-24 84.9 25.8 4.4e-05 23.1 1.5 9.5 6 2 3 9 9 9 7 TPR repeat TPR_16 PF13432.6 EPS28231.1 - 2.1e-24 85.9 4.9 6.2e-05 23.6 0.1 6.8 4 2 1 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 EPS28231.1 - 6e-22 77.7 18.9 8.6e-05 22.8 0.5 7.8 3 2 4 7 7 7 5 Tetratricopeptide repeat TPR_6 PF13174.6 EPS28231.1 - 5e-19 67.6 14.2 0.04 14.5 0.0 9.8 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_7 PF13176.6 EPS28231.1 - 5.5e-17 60.5 15.1 0.03 14.3 0.1 9.7 9 1 0 9 9 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 EPS28231.1 - 9.5e-17 60.9 9.5 0.0051 16.9 0.5 7.2 3 2 5 8 8 8 6 Tetratricopeptide repeat ANAPC3 PF12895.7 EPS28231.1 - 2.9e-12 46.7 9.2 1.7e-08 34.6 1.9 3.7 3 1 1 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 EPS28231.1 - 1.6e-08 34.1 9.4 0.0045 16.2 0.4 5.3 1 1 4 5 5 5 2 Tetratricopeptide repeat TPR_21 PF09976.9 EPS28231.1 - 2.4e-05 24.1 6.5 0.19 11.5 0.0 4.6 3 2 1 5 5 5 1 Tetratricopeptide repeat-like domain BTAD PF03704.17 EPS28231.1 - 3.6e-05 24.2 5.9 0.13 12.7 0.0 3.6 3 0 0 3 3 3 1 Bacterial transcriptional activator domain TPR_MalT PF17874.1 EPS28231.1 - 0.0022 17.4 4.9 0.079 12.3 0.0 3.5 2 2 2 4 4 4 1 MalT-like TPR region DUF2225 PF09986.9 EPS28231.1 - 0.0072 16.1 5.4 1.1 8.9 0.0 3.0 3 1 0 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_20 PF14561.6 EPS28231.1 - 0.023 15.0 0.6 1.8 8.9 0.1 3.7 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 EPS28231.1 - 5.6 7.0 18.9 30 4.7 0.2 6.7 10 0 0 10 10 7 0 Tetratricopeptide repeat Ribosomal_L3 PF00297.22 EPS28232.1 - 1e-183 610.4 10.5 1.2e-183 610.2 10.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 SKN1 PF03935.15 EPS28235.1 - 2.6e-215 715.5 1.3 4e-215 715.0 1.3 1.3 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Chorismate_bind PF00425.18 EPS28236.1 - 1.2e-65 221.7 0.0 5.8e-65 219.4 0.0 1.8 2 0 0 2 2 2 1 chorismate binding enzyme Methyltransf_31 PF13847.6 EPS28237.1 - 1.5e-09 37.8 0.0 5e-09 36.1 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPS28237.1 - 4.2e-08 33.9 0.0 1.1e-07 32.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPS28237.1 - 6.9e-08 33.1 0.0 1.6e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPS28237.1 - 1.3e-05 25.1 0.0 2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS28237.1 - 0.00012 22.6 0.0 0.00025 21.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPS28237.1 - 0.008 15.5 0.0 0.013 14.9 0.0 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family GCD14 PF08704.10 EPS28237.1 - 0.19 11.4 0.0 0.43 10.2 0.0 1.5 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit BCDHK_Adom3 PF10436.9 EPS28239.1 - 1e-73 246.5 0.0 1.4e-73 246.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EPS28239.1 - 8.9e-13 48.7 0.0 1.7e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EPS28239.1 - 0.092 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2948 PF11164.8 EPS28240.1 - 0.15 12.1 1.6 2.3 8.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2948) Lyase_1 PF00206.20 EPS28243.1 - 5.8e-22 78.5 0.0 1.2e-21 77.4 0.0 1.5 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 EPS28243.1 - 5.5e-17 62.1 0.1 2.3e-16 60.1 0.0 2.1 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus BLUF PF04940.12 EPS28243.1 - 0.091 12.9 0.1 0.46 10.6 0.0 2.2 3 0 0 3 3 3 0 Sensors of blue-light using FAD Exo70 PF03081.15 EPS28244.1 - 6e-79 265.8 0.0 2.2e-78 263.9 0.0 1.8 2 0 0 2 2 2 1 Exo70 exocyst complex subunit PLA2_B PF01735.18 EPS28245.1 - 3.4e-28 98.3 0.0 6e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 Lysophospholipase catalytic domain DSPc PF00782.20 EPS28246.1 - 2.1e-09 37.3 0.0 4.1e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EPS28246.1 - 2e-06 27.5 0.0 3.2e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EPS28246.1 - 0.024 14.6 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family PPR_3 PF13812.6 EPS28248.1 - 1.3e-07 31.5 0.0 0.0046 17.0 0.0 4.7 4 1 1 5 5 5 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 EPS28248.1 - 1.6e-07 31.4 0.0 0.0021 18.2 0.0 4.7 5 1 0 5 5 5 2 PPR repeat family PPR_long PF17177.4 EPS28248.1 - 2.1e-07 30.5 0.2 0.0046 16.4 0.1 3.4 1 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 EPS28248.1 - 0.0071 16.5 8.5 1.3 9.4 0.1 5.7 6 0 0 6 6 6 1 PPR repeat LSM PF01423.22 EPS28249.1 - 2.8e-18 65.3 0.0 4.1e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EPS28249.1 - 0.0024 18.0 0.0 0.0029 17.7 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Hat1_N PF10394.9 EPS28250.1 - 2.1e-52 177.6 0.0 3.6e-52 176.8 0.0 1.4 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus APH PF01636.23 EPS28252.1 - 8.5e-11 42.2 0.0 6e-10 39.5 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Cellulase PF00150.18 EPS28253.1 - 1.1e-18 67.7 1.2 1.4e-18 67.3 1.2 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Lsr2 PF11774.8 EPS28253.1 - 0.12 12.6 0.0 1.3 9.2 0.0 2.3 2 0 0 2 2 2 0 Lsr2 CFEM PF05730.11 EPS28254.1 - 7.8e-08 32.3 11.0 1.5e-07 31.4 11.0 1.4 1 0 0 1 1 1 1 CFEM domain STE2 PF02116.15 EPS28254.1 - 0.0076 15.6 9.0 0.018 14.4 9.0 1.5 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR Zip PF02535.22 EPS28255.1 - 4.6e-39 134.5 15.8 9.7e-31 107.2 7.1 3.0 2 1 0 2 2 2 2 ZIP Zinc transporter WD40 PF00400.32 EPS28256.1 - 2.3e-37 126.3 26.5 3.2e-07 30.9 0.1 8.3 9 0 0 9 9 9 6 WD domain, G-beta repeat F-box-like PF12937.7 EPS28256.1 - 2.4e-10 40.1 0.7 5.4e-10 39.0 0.7 1.6 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 EPS28256.1 - 2.1e-08 34.3 1.3 0.33 11.3 0.0 6.1 1 1 5 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EPS28256.1 - 3.8e-06 25.8 9.5 0.034 12.8 0.1 5.6 3 1 4 7 7 7 3 Nucleoporin Nup120/160 WD40_like PF17005.5 EPS28256.1 - 0.00048 19.5 0.0 0.16 11.3 0.0 2.9 1 1 2 3 3 3 2 WD40-like domain F-box PF00646.33 EPS28256.1 - 0.00093 19.0 1.0 0.0022 17.8 1.0 1.7 1 0 0 1 1 1 1 F-box domain PALB2_WD40 PF16756.5 EPS28256.1 - 0.027 13.4 3.3 14 4.5 0.0 4.0 2 1 1 4 4 4 0 Partner and localizer of BRCA2 WD40 domain Zn_clus PF00172.18 EPS28258.1 - 1.3e-07 31.6 8.7 2.5e-07 30.7 8.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_carr PF00153.27 EPS28259.1 - 5.4e-46 154.5 3.6 4e-16 58.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF155 PF02582.14 EPS28261.1 - 6.6e-53 179.4 0.1 1e-52 178.8 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.6 EPS28261.1 - 0.069 13.6 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 U3_snoRNA_assoc PF08297.11 EPS28262.1 - 1.6e-18 67.2 0.9 1.6e-18 67.2 0.9 4.1 2 1 1 3 3 3 1 U3 snoRNA associated CCDC71L PF15374.6 EPS28262.1 - 8.6 5.5 23.2 18 4.4 22.9 1.6 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 71L CTK3 PF12243.8 EPS28263.1 - 1.1e-50 170.8 0.1 1.6e-50 170.3 0.1 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.8 EPS28263.1 - 2.8e-16 59.4 9.0 2.8e-16 59.4 9.0 2.1 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus Voltage_CLC PF00654.20 EPS28264.1 - 1.7e-89 300.5 28.4 1.7e-89 300.5 28.4 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EPS28264.1 - 0.0077 16.7 0.0 5.4 7.6 0.0 2.5 2 0 0 2 2 2 2 CBS domain AAA_5 PF07728.14 EPS28265.1 - 2.8e-129 425.8 0.9 6.9e-22 77.9 0.0 9.7 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 EPS28265.1 - 4.4e-49 165.1 9.4 1.9e-17 63.4 0.0 5.4 5 0 0 5 5 4 4 Midasin AAA lid domain AAA_lid_5 PF17865.1 EPS28265.1 - 3.5e-32 110.6 0.1 1e-30 105.9 0.1 2.9 2 0 0 2 2 2 1 Midasin AAA lid domain AAA_7 PF12775.7 EPS28265.1 - 4.6e-32 111.0 1.7 7e-06 25.7 0.0 7.4 7 0 0 7 7 7 6 P-loop containing dynein motor region AAA_3 PF07726.11 EPS28265.1 - 2.3e-30 105.1 0.0 7.9e-11 41.9 0.0 7.5 7 0 0 7 7 7 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 EPS28265.1 - 2.7e-28 99.0 0.0 0.00016 22.1 0.0 7.1 6 0 0 6 6 6 6 ATPase family associated with various cellular activities (AAA) Dynein_heavy PF03028.15 EPS28265.1 - 2.7e-22 79.1 0.0 2.1e-05 24.6 0.0 8.4 8 1 0 8 8 8 4 Dynein heavy chain region D6 P-loop domain AAA_16 PF13191.6 EPS28265.1 - 1.1e-21 78.0 21.6 0.00017 22.0 0.4 9.8 8 2 0 8 8 7 5 AAA ATPase domain ABC_tran PF00005.27 EPS28265.1 - 1.4e-18 67.7 0.3 0.0026 18.3 0.0 7.0 6 0 0 6 6 6 3 ABC transporter AAA_33 PF13671.6 EPS28265.1 - 1.1e-17 64.5 0.1 0.0018 18.4 0.0 7.1 7 0 0 7 7 6 3 AAA domain AAA_14 PF13173.6 EPS28265.1 - 2.1e-17 63.4 0.0 0.011 15.7 0.0 7.4 7 0 0 7 7 6 2 AAA domain AAA_22 PF13401.6 EPS28265.1 - 2.5e-17 63.4 2.5 0.064 13.5 0.0 8.2 8 0 0 8 8 7 4 AAA domain AAA_30 PF13604.6 EPS28265.1 - 9.2e-17 61.4 0.0 0.0043 16.8 0.0 7.0 6 2 0 6 6 6 4 AAA domain AAA_18 PF13238.6 EPS28265.1 - 2.1e-16 60.6 0.6 0.14 12.7 0.0 7.0 6 0 0 6 6 6 3 AAA domain AAA_6 PF12774.7 EPS28265.1 - 4.9e-16 58.6 0.0 0.074 12.0 0.0 8.4 8 0 0 8 8 7 2 Hydrolytic ATP binding site of dynein motor region TsaE PF02367.17 EPS28265.1 - 5.4e-16 58.7 4.8 0.16 12.0 0.1 7.3 7 0 0 7 7 7 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 EPS28265.1 - 1.1e-15 57.7 0.0 0.018 14.8 0.0 6.1 6 0 0 6 6 5 3 Sigma-54 interaction domain Mg_chelatase PF01078.21 EPS28265.1 - 1.6e-13 50.5 1.3 1.3 8.3 0.0 9.1 9 1 0 9 9 9 2 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 EPS28265.1 - 3.8e-13 49.7 2.0 0.13 12.1 0.2 6.4 6 0 0 6 6 6 3 RsgA GTPase RNA_helicase PF00910.22 EPS28265.1 - 5.4e-13 49.3 1.1 0.88 10.0 0.0 6.8 7 0 0 7 7 6 4 RNA helicase Zeta_toxin PF06414.12 EPS28265.1 - 1e-12 47.8 1.1 1.2 8.3 0.0 7.2 7 0 0 7 7 7 3 Zeta toxin RuvB_N PF05496.12 EPS28265.1 - 4.7e-12 45.9 4.4 0.27 11.0 0.0 7.0 7 0 0 7 7 7 3 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 EPS28265.1 - 6.8e-12 45.6 6.7 0.15 12.0 0.1 5.6 5 0 0 5 5 5 4 NACHT domain SRP54 PF00448.22 EPS28265.1 - 7.3e-11 42.1 5.8 0.041 13.5 0.0 5.9 6 0 0 6 6 6 2 SRP54-type protein, GTPase domain Rad17 PF03215.15 EPS28265.1 - 3.8e-10 40.0 2.7 0.022 14.7 0.0 5.7 6 0 0 6 6 5 1 Rad17 P-loop domain ATPase_2 PF01637.18 EPS28265.1 - 7.6e-10 39.1 0.0 1.3 8.9 0.0 6.1 6 0 0 6 6 6 1 ATPase domain predominantly from Archaea AAA_28 PF13521.6 EPS28265.1 - 8.2e-10 39.2 5.2 0.28 11.4 0.0 6.6 6 0 0 6 6 6 2 AAA domain AAA_19 PF13245.6 EPS28265.1 - 1e-09 38.9 3.9 2.1 8.6 0.1 6.7 6 1 0 6 6 5 1 AAA domain MMR_HSR1 PF01926.23 EPS28265.1 - 1.6e-09 37.9 2.3 0.018 15.1 0.0 6.8 7 0 0 7 7 6 1 50S ribosome-binding GTPase T2SSE PF00437.20 EPS28265.1 - 3.6e-09 36.1 3.4 0.25 10.3 0.0 6.4 6 0 0 6 6 6 1 Type II/IV secretion system protein PduV-EutP PF10662.9 EPS28265.1 - 7.3e-09 35.5 6.4 0.094 12.5 0.0 6.0 6 0 0 6 6 6 2 Ethanolamine utilisation - propanediol utilisation Sigma54_activ_2 PF14532.6 EPS28265.1 - 1.4e-08 34.9 0.5 0.052 13.7 0.1 5.3 5 0 0 5 5 4 2 Sigma-54 interaction domain Roc PF08477.13 EPS28265.1 - 1.7e-08 34.7 2.3 6.8 6.9 0.1 6.3 6 0 0 6 6 6 0 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 EPS28265.1 - 2.6e-08 33.7 4.6 3 7.4 0.0 6.4 7 0 0 7 7 5 0 AAA domain DUF815 PF05673.13 EPS28265.1 - 3.8e-08 32.8 2.8 0.47 9.6 0.1 5.9 6 0 0 6 6 6 2 Protein of unknown function (DUF815) AAA_29 PF13555.6 EPS28265.1 - 7.8e-08 32.0 1.6 1 9.2 0.0 6.2 6 0 0 6 6 6 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 EPS28265.1 - 1.7e-07 31.1 0.0 1.3 8.7 0.0 5.5 5 0 0 5 5 5 1 IstB-like ATP binding protein TniB PF05621.11 EPS28265.1 - 1.7e-07 30.8 0.2 1.8 8.0 0.0 5.9 6 0 0 6 6 5 1 Bacterial TniB protein MCM PF00493.23 EPS28265.1 - 1.2e-06 27.8 0.8 0.98 8.5 0.0 5.2 6 0 0 6 6 5 1 MCM P-loop domain AAA_24 PF13479.6 EPS28265.1 - 1.7e-06 27.9 0.6 2.6 7.7 0.0 5.8 6 0 0 6 6 5 0 AAA domain ATP_bind_1 PF03029.17 EPS28265.1 - 3.2e-06 27.1 3.4 3.1 7.5 0.1 5.5 5 0 0 5 5 4 0 Conserved hypothetical ATP binding protein Bac_DnaA PF00308.18 EPS28265.1 - 4e-06 26.8 0.0 1.5 8.6 0.0 4.0 4 0 0 4 4 3 2 Bacterial dnaA protein Viral_helicase1 PF01443.18 EPS28265.1 - 4.6e-06 26.6 0.2 0.42 10.3 0.0 5.0 5 0 0 5 5 4 1 Viral (Superfamily 1) RNA helicase SRPRB PF09439.10 EPS28265.1 - 1e-05 25.0 4.9 2.8 7.3 0.0 6.0 6 0 0 6 6 6 0 Signal recognition particle receptor beta subunit AAA_9 PF12781.7 EPS28265.1 - 2.7e-05 23.4 0.0 0.21 10.7 0.0 4.2 4 0 0 4 4 4 1 ATP-binding dynein motor region cobW PF02492.19 EPS28265.1 - 5.9e-05 22.7 4.3 3.8 7.1 0.1 6.0 7 0 0 7 7 6 0 CobW/HypB/UreG, nucleotide-binding domain ResIII PF04851.15 EPS28265.1 - 7.7e-05 22.8 0.2 2.2 8.3 0.0 4.6 5 0 0 5 5 4 1 Type III restriction enzyme, res subunit NTPase_1 PF03266.15 EPS28265.1 - 0.00015 21.7 12.7 2.6 7.9 0.1 5.7 6 0 0 6 6 5 0 NTPase NB-ARC PF00931.22 EPS28265.1 - 0.00021 20.6 2.4 6.2 5.9 0.0 5.4 5 0 0 5 5 5 0 NB-ARC domain TIP49 PF06068.13 EPS28265.1 - 0.00036 19.8 4.5 0.58 9.3 0.0 4.6 5 0 0 5 5 5 1 TIP49 P-loop domain CbiA PF01656.23 EPS28265.1 - 0.00083 19.4 0.4 1.3 9.1 0.0 4.0 4 0 0 4 4 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain DAP3 PF10236.9 EPS28265.1 - 0.0016 17.7 1.8 0.44 9.7 0.0 4.0 4 0 0 4 4 4 1 Mitochondrial ribosomal death-associated protein 3 FeoB_N PF02421.18 EPS28265.1 - 0.0017 17.9 7.0 0.21 11.1 0.1 5.2 6 0 0 6 6 5 1 Ferrous iron transport protein B PhoH PF02562.16 EPS28265.1 - 0.0018 17.7 0.4 4.3 6.7 0.0 4.2 4 0 0 4 4 4 0 PhoH-like protein DnaB_C PF03796.15 EPS28265.1 - 0.002 17.5 3.0 1.9 7.8 0.1 4.6 5 0 0 5 5 4 1 DnaB-like helicase C terminal domain ATPase PF06745.13 EPS28265.1 - 0.0021 17.5 0.2 29 3.9 0.0 4.8 5 0 0 5 5 4 0 KaiC CPT PF07931.12 EPS28265.1 - 0.0056 16.5 0.7 4 7.3 0.0 4.7 4 1 0 4 4 3 0 Chloramphenicol phosphotransferase-like protein KTI12 PF08433.10 EPS28265.1 - 0.0079 15.7 0.3 19 4.6 0.0 4.7 5 0 0 5 5 4 0 Chromatin associated protein KTI12 G-alpha PF00503.20 EPS28265.1 - 0.021 14.0 2.0 8 5.5 0.0 4.9 6 0 0 6 6 5 0 G-protein alpha subunit MobB PF03205.14 EPS28265.1 - 0.021 14.7 9.8 26 4.7 0.2 5.9 6 0 0 6 6 6 0 Molybdopterin guanine dinucleotide synthesis protein B Ploopntkinase3 PF18751.1 EPS28265.1 - 0.028 14.3 0.5 36 4.2 0.0 4.4 5 0 0 5 5 4 0 P-loop Nucleotide Kinase3 Gtr1_RagA PF04670.12 EPS28265.1 - 0.052 12.9 0.0 34 3.7 0.0 4.0 4 0 0 4 4 3 0 Gtr1/RagA G protein conserved region Septin PF00735.18 EPS28265.1 - 0.053 12.8 1.9 7.1 5.8 0.1 4.1 6 0 0 6 6 4 0 Septin MeaB PF03308.16 EPS28265.1 - 0.11 11.5 4.6 2.6 6.9 0.2 3.2 4 0 0 4 4 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 EPS28265.1 - 0.14 12.2 1.0 36 4.4 0.0 3.8 3 0 0 3 3 2 0 Dynamin family dNK PF01712.19 EPS28265.1 - 0.14 11.9 5.6 6.9 6.5 0.0 4.5 5 0 0 5 5 4 0 Deoxynucleoside kinase DEAD PF00270.29 EPS28265.1 - 0.26 11.0 0.8 24 4.7 0.1 3.6 4 0 0 4 4 3 0 DEAD/DEAH box helicase Y_phosphatase PF00102.27 EPS28265.1 - 0.45 10.0 2.1 11 5.4 0.0 3.8 5 0 0 5 5 4 0 Protein-tyrosine phosphatase Arf PF00025.21 EPS28265.1 - 0.58 9.6 3.7 10 5.5 0.0 4.1 6 0 0 6 6 3 0 ADP-ribosylation factor family TrwB_AAD_bind PF10412.9 EPS28265.1 - 0.88 8.4 4.3 8.1 5.2 0.1 3.7 4 0 0 4 4 4 0 Type IV secretion-system coupling protein DNA-binding domain PRCC PF10253.9 EPS28266.1 - 2.9e-37 129.5 4.6 2.9e-37 129.5 4.6 2.8 2 0 0 2 2 2 1 Mitotic checkpoint regulator, MAD2B-interacting VWA PF00092.28 EPS28266.1 - 0.034 14.4 0.3 0.064 13.5 0.3 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain Pkinase PF00069.25 EPS28267.1 - 4.7e-71 239.3 0.0 6.4e-71 238.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS28267.1 - 1e-36 126.6 0.0 1.6e-36 125.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EPS28267.1 - 1.7e-06 27.6 0.0 3.5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EPS28267.1 - 0.029 14.3 1.6 0.042 13.8 0.6 1.9 2 1 0 2 2 2 0 Phosphotransferase enzyme family Ndc1_Nup PF09531.10 EPS28267.1 - 0.47 9.1 8.2 0.57 8.8 8.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFIIA PF03153.13 EPS28267.1 - 0.64 10.0 22.8 0.88 9.5 22.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCSAP PF15748.5 EPS28267.1 - 0.67 10.1 13.6 1.1 9.3 13.6 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated SOG2 PF10428.9 EPS28267.1 - 2.9 7.0 16.5 3.8 6.6 16.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF3408 PF11888.8 EPS28267.1 - 3.7 7.7 8.4 5.7 7.1 7.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3408) Suf PF05843.14 EPS28267.1 - 4.8 7.1 13.8 6.6 6.6 13.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Menin PF05053.13 EPS28267.1 - 9.9 4.4 8.2 13 4.0 8.2 1.1 1 0 0 1 1 1 0 Menin zf-Tim10_DDP PF02953.15 EPS28268.1 - 4e-23 80.9 1.0 5.2e-23 80.5 1.0 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Lectin_leg-like PF03388.13 EPS28269.1 - 1.6e-65 220.7 0.0 2.1e-65 220.3 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family CRIM PF16978.5 EPS28271.1 - 1.7e-41 141.6 0.0 3.4e-41 140.7 0.0 1.5 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 EPS28271.1 - 1.3e-24 86.5 0.8 2.3e-24 85.8 0.3 1.7 2 0 0 2 2 2 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology Glyco_hydro_28 PF00295.17 EPS28272.1 - 7.4e-117 390.0 20.4 8.6e-117 389.8 20.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 RFC1 PF08519.12 EPS28274.1 - 9.6e-60 201.3 0.3 2.3e-59 200.1 0.1 1.8 2 0 0 2 2 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 EPS28274.1 - 5.2e-14 52.4 0.0 1.8e-13 50.6 0.0 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 EPS28274.1 - 1.3e-09 38.6 0.1 3.9e-09 37.0 0.1 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EPS28274.1 - 3.1e-05 24.0 0.0 9.7e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_33 PF13671.6 EPS28274.1 - 0.00062 19.9 0.0 0.0024 18.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EPS28274.1 - 0.00092 19.5 0.0 0.0035 17.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EPS28274.1 - 0.0016 18.9 0.1 0.0099 16.3 0.1 2.3 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EPS28274.1 - 0.0022 17.8 0.0 0.0046 16.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 EPS28274.1 - 0.013 15.6 0.0 0.046 13.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EPS28274.1 - 0.015 15.9 0.1 0.074 13.6 0.1 2.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EPS28274.1 - 0.035 13.8 1.9 0.044 13.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EPS28274.1 - 0.06 13.3 0.3 0.68 9.8 0.1 2.3 1 1 1 2 2 2 0 NTPase AAA_28 PF13521.6 EPS28274.1 - 0.22 11.8 0.0 0.22 11.8 0.0 2.2 2 0 0 2 2 1 0 AAA domain AT_hook PF02178.19 EPS28274.1 - 0.43 10.6 5.9 0.095 12.6 0.6 3.1 2 0 0 2 2 1 0 AT hook motif DUF4889 PF16230.5 EPS28274.1 - 1.3 9.3 8.4 8.2 6.7 8.4 2.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4889) Ribosomal_L16 PF00252.18 EPS28275.1 - 4.8e-31 107.5 0.1 6.1e-31 107.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e B5 PF03484.15 EPS28275.1 - 0.16 12.2 0.0 0.28 11.5 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetase B5 domain DNA_pol3_delta2 PF13177.6 EPS28276.1 - 5.5e-11 42.5 0.1 1.2e-10 41.4 0.1 1.6 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 EPS28276.1 - 2.6e-06 27.9 0.1 5.7e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EPS28276.1 - 0.0002 21.6 0.2 0.00065 20.0 0.1 1.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EPS28276.1 - 0.0013 19.2 0.9 0.0095 16.3 0.3 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 EPS28276.1 - 0.01 15.6 0.4 0.025 14.3 0.4 1.6 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 EPS28276.1 - 0.01 15.8 0.0 0.044 13.7 0.0 2.0 2 0 0 2 2 2 0 Rad17 P-loop domain Rep_fac_C PF08542.11 EPS28276.1 - 0.03 14.7 0.1 0.26 11.7 0.0 2.2 2 0 0 2 2 2 0 Replication factor C C-terminal domain ABC_tran PF00005.27 EPS28276.1 - 0.032 14.8 0.0 0.062 13.8 0.0 1.5 1 1 0 1 1 1 0 ABC transporter T4SS-DNA_transf PF02534.14 EPS28276.1 - 0.13 11.1 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer CtaG_Cox11 PF04442.14 EPS28277.1 - 1.8e-60 203.3 0.0 2.6e-60 202.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 TMEM135_C_rich PF15982.5 EPS28278.1 - 7.8e-07 29.8 0.1 7.3e-05 23.4 0.1 2.7 2 1 0 2 2 2 1 N-terminal cysteine-rich region of Transmembrane protein 135 Cation_ATPase_C PF00689.21 EPS28278.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.6 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus HLH PF00010.26 EPS28279.1 - 6.1e-07 29.3 0.0 1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CENP-Q PF13094.6 EPS28280.1 - 2.7e-47 161.1 7.7 2.7e-47 161.1 7.7 1.6 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit YkyA PF10368.9 EPS28280.1 - 0.47 10.1 10.0 3.4 7.3 0.3 2.4 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein Macoilin PF09726.9 EPS28280.1 - 0.93 8.0 10.8 1.3 7.5 10.8 1.3 1 1 0 1 1 1 0 Macoilin family AATF-Che1 PF13339.6 EPS28280.1 - 1.8 9.2 9.0 0.37 11.5 2.3 2.3 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor COG2 PF06148.11 EPS28280.1 - 8 6.6 8.3 2.3 8.3 3.2 2.4 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 SPO22 PF08631.10 EPS28282.1 - 9.6e-10 38.4 0.6 4.7e-07 29.6 0.0 2.8 2 0 0 2 2 2 2 Meiosis protein SPO22/ZIP4 like Glyco_transf_7C PF02709.14 EPS28282.1 - 0.19 11.4 0.0 0.43 10.3 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase TPR_2 PF07719.17 EPS28282.1 - 4.3 7.7 10.6 0.85 9.9 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat WD40 PF00400.32 EPS28284.1 - 2.9e-17 62.7 4.5 0.0021 18.8 0.0 9.0 9 0 0 9 9 9 4 WD domain, G-beta repeat SGL PF08450.12 EPS28284.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region Neugrin PF06413.11 EPS28285.1 - 1.2e-13 51.6 0.5 2.1e-13 50.8 0.5 1.4 1 0 0 1 1 1 1 Neugrin MRP-L20 PF12824.7 EPS28285.1 - 4.9e-06 26.8 9.0 1.7e-05 25.0 9.0 1.8 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Rgp1 PF08737.10 EPS28286.1 - 2.6e-142 474.9 0.0 4.3e-142 474.2 0.0 1.4 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.29 EPS28286.1 - 3.5e-05 23.9 0.0 7.9e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EPS28286.1 - 0.015 15.8 0.0 0.14 12.6 0.0 2.6 3 0 0 3 3 3 0 Arrestin (or S-antigen), C-terminal domain Mob1_phocein PF03637.17 EPS28287.1 - 1.4e-73 246.5 0.0 1.6e-73 246.3 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family OSCP PF00213.18 EPS28288.1 - 2.2e-46 158.1 2.3 2.6e-46 157.9 2.3 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DUF1539 PF07560.11 EPS28288.1 - 0.06 13.4 0.3 7.4 6.7 0.0 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) Gasdermin_C PF17708.1 EPS28288.1 - 0.072 13.2 0.3 0.12 12.5 0.3 1.3 1 0 0 1 1 1 0 Gasdermin PUB domain Pox_A51 PF04948.13 EPS28288.1 - 0.14 11.0 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus A51 protein Glyco_hydro_63 PF03200.16 EPS28289.1 - 4.4e-05 22.4 11.9 9.7e-05 21.3 0.2 4.0 5 1 0 5 5 5 2 Glycosyl hydrolase family 63 C-terminal domain Fn3-like PF14310.6 EPS28289.1 - 0.14 12.2 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 Fibronectin type III-like domain SlyX PF04102.12 EPS28290.1 - 0.0017 18.9 1.4 0.0025 18.4 1.4 1.2 1 0 0 1 1 1 1 SlyX ADIP PF11559.8 EPS28290.1 - 0.0082 16.2 1.3 0.01 15.9 1.3 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DivIC PF04977.15 EPS28290.1 - 0.05 13.4 2.2 0.068 12.9 2.2 1.2 1 0 0 1 1 1 0 Septum formation initiator Bromodomain PF00439.25 EPS28291.1 - 3.1e-09 36.8 0.1 4.6e-06 26.6 0.0 3.0 3 0 0 3 3 3 2 Bromodomain DUF465 PF04325.13 EPS28291.1 - 0.28 11.2 1.2 0.55 10.3 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF465) Diphthamide_syn PF01866.17 EPS28292.1 - 3.5e-117 391.2 0.0 4.8e-117 390.7 0.0 1.2 1 0 0 1 1 1 1 Putative diphthamide synthesis protein HMGL-like PF00682.19 EPS28293.1 - 4.7e-44 150.9 0.6 1.6e-43 149.1 0.6 1.7 1 1 0 1 1 1 1 HMGL-like PE PF00934.20 EPS28293.1 - 0.13 12.6 2.9 0.35 11.2 0.3 2.5 2 1 0 2 2 2 0 PE family DUF1674 PF07896.12 EPS28294.1 - 5.5e-20 71.6 3.9 1.5e-19 70.2 3.9 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) Aminotran_3 PF00202.21 EPS28295.1 - 7.1e-114 380.6 0.0 9e-114 380.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EPS28295.1 - 2.2e-05 23.8 0.0 3.1e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II CLN3 PF02487.17 EPS28296.1 - 5.9e-162 539.3 1.7 6.7e-162 539.1 1.7 1.0 1 0 0 1 1 1 1 CLN3 protein Abhydrolase_3 PF07859.13 EPS28297.1 - 1.2e-35 123.3 0.4 2.1e-22 80.1 0.0 2.9 3 1 1 4 4 4 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EPS28297.1 - 0.038 12.9 0.0 0.062 12.2 0.0 1.3 1 0 0 1 1 1 0 Steryl acetyl hydrolase RAP1 PF07218.11 EPS28297.1 - 0.46 8.7 1.9 0.66 8.2 1.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MFS_1 PF07690.16 EPS28298.1 - 3.3e-31 108.5 20.3 3.3e-31 108.5 20.3 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS28298.1 - 2.1e-10 40.1 8.1 2.1e-10 40.1 8.1 3.4 2 1 1 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EPS28298.1 - 0.0012 17.4 3.2 0.0022 16.5 3.2 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Rxt3 PF08642.10 EPS28299.1 - 9.6e-41 139.5 0.0 2.9e-40 137.9 0.0 1.9 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.19 EPS28299.1 - 0.005 16.9 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 LCCL domain DUF3915 PF13054.6 EPS28299.1 - 1.1 9.2 2.6 2.7 8.0 2.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) Carn_acyltransf PF00755.20 EPS28300.1 - 7e-206 685.4 0.0 8e-206 685.2 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Atg14 PF10186.9 EPS28301.1 - 0.0017 17.5 1.9 0.0084 15.2 0.3 2.1 2 0 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2046 PF09755.9 EPS28301.1 - 0.0049 16.2 2.3 0.01 15.1 0.5 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) DMSP_lyase PF16867.5 EPS28301.1 - 0.022 14.4 0.5 0.022 14.4 0.5 1.8 2 0 0 2 2 2 0 Dimethlysulfonioproprionate lyase DivIC PF04977.15 EPS28301.1 - 0.04 13.7 0.7 0.04 13.7 0.7 2.3 2 0 0 2 2 2 0 Septum formation initiator TMCO5 PF14992.6 EPS28301.1 - 0.051 13.1 0.8 0.25 10.9 0.0 1.9 2 0 0 2 2 2 0 TMCO5 family BBS2_C PF14782.6 EPS28301.1 - 0.11 11.3 1.7 1.8 7.2 0.0 2.0 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, C-terminal SlyX PF04102.12 EPS28301.1 - 0.12 13.1 12.9 0.97 10.1 0.5 2.4 2 0 0 2 2 2 0 SlyX HSCB_C PF07743.13 EPS28301.1 - 0.23 11.9 5.7 6.8 7.3 0.2 2.2 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain DUF733 PF05306.11 EPS28301.1 - 0.29 11.5 6.3 1 9.7 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF733) DASH_Spc34 PF08657.10 EPS28301.1 - 0.51 10.1 5.3 1.8 8.3 3.4 2.1 2 0 0 2 2 2 0 DASH complex subunit Spc34 UPF0242 PF06785.11 EPS28301.1 - 1.9 8.6 8.2 11 6.1 5.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus MerR-DNA-bind PF09278.11 EPS28301.1 - 1.9 9.1 12.3 0.15 12.6 1.3 2.4 2 0 0 2 2 2 0 MerR, DNA binding DUF2968 PF11180.8 EPS28301.1 - 2 8.0 19.2 0.12 12.0 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Spc24 PF08286.11 EPS28301.1 - 3.9 7.8 6.6 29 5.0 0.1 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 FlaC_arch PF05377.11 EPS28301.1 - 4.7 7.7 4.8 5.9 7.4 0.1 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) TFIIA PF03153.13 EPS28301.1 - 7.1 6.5 14.7 10 6.0 14.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF5320 PF17253.2 EPS28301.1 - 8.4 7.5 6.9 1.1 10.3 0.2 2.5 2 1 0 2 2 2 0 Family of unknown function (DUF5320) MFS_1 PF07690.16 EPS28302.1 - 4.7e-25 88.3 28.8 2.9e-24 85.6 25.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4131 PF13567.6 EPS28302.1 - 0.48 10.1 0.0 0.48 10.1 0.0 3.6 4 2 0 4 4 4 0 Domain of unknown function (DUF4131) Phage_holin_3_6 PF07332.11 EPS28302.1 - 1.2 9.2 0.0 1.2 9.2 0.0 3.6 5 0 0 5 5 5 0 Putative Actinobacterial Holin-X, holin superfamily III Pterin_4a PF01329.19 EPS28303.1 - 8.5e-23 80.4 0.0 1.2e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Sec62 PF03839.16 EPS28305.1 - 2e-77 259.6 1.7 2e-77 259.6 1.7 1.7 2 0 0 2 2 2 1 Translocation protein Sec62 Lectin_C PF00059.21 EPS28306.1 - 0.083 13.6 0.1 0.18 12.5 0.1 1.6 1 0 0 1 1 1 0 Lectin C-type domain Me-amine-dh_L PF02975.14 EPS28306.1 - 0.15 12.6 0.3 5.6 7.5 0.0 3.2 4 0 0 4 4 4 0 Methylamine dehydrogenase, L chain FSA_C PF10479.9 EPS28306.1 - 0.39 8.8 1.9 0.68 8.0 1.9 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Pyr_redox_2 PF07992.14 EPS28308.1 - 1.9e-09 37.2 0.0 3.9e-09 36.2 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPS28308.1 - 0.00084 19.5 0.0 0.002 18.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EPS28308.1 - 0.018 13.7 0.0 0.031 13.0 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.6 EPS28308.1 - 0.024 14.6 0.1 0.075 13.0 0.0 1.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 EPS28308.1 - 0.2 12.2 0.0 8.1 7.1 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Cerato-platanin PF07249.12 EPS28309.1 - 1.2e-36 125.4 0.3 2.4e-36 124.4 0.1 1.5 1 1 1 2 2 2 1 Cerato-platanin Barwin PF00967.17 EPS28309.1 - 0.025 14.4 0.1 0.035 13.9 0.1 1.3 1 1 0 1 1 1 0 Barwin family Git3 PF11710.8 EPS28311.1 - 7.8e-23 81.3 9.3 7.8e-23 81.3 9.3 1.9 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 EPS28311.1 - 7e-12 45.3 1.0 7.2e-11 42.0 0.0 2.5 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Nterm_IS4 PF13006.7 EPS28311.1 - 0.099 12.9 0.1 0.37 11.0 0.1 2.0 1 0 0 1 1 1 0 Insertion element 4 transposase N-terminal ArenaCapSnatch PF17296.2 EPS28311.1 - 0.2 11.1 0.0 0.31 10.4 0.0 1.2 1 0 0 1 1 1 0 Arenavirus cap snatching domain CDH-cyt PF16010.5 EPS28312.1 - 3.2e-16 59.6 0.0 5.2e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 EPS28312.1 - 3.4e-09 37.0 10.7 7.9e-09 35.8 10.7 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 EPS28312.1 - 0.00041 20.1 1.4 0.0011 18.8 1.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) CD47 PF04549.14 EPS28312.1 - 0.037 14.2 0.8 0.037 14.2 0.8 1.9 2 0 0 2 2 2 0 CD47 transmembrane region DUF4199 PF13858.6 EPS28312.1 - 1.8 8.9 5.9 1.4 9.3 1.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Abhydrolase_3 PF07859.13 EPS28313.1 - 6.8e-44 150.3 0.1 5.9e-35 121.0 0.0 3.7 4 0 0 4 4 4 2 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EPS28313.1 - 4.2e-18 65.4 0.0 7e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 EPS28313.1 - 0.027 13.7 0.0 0.059 12.6 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 ParA PF10609.9 EPS28314.1 - 2.8e-85 285.7 0.0 9.6e-85 283.9 0.0 1.8 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EPS28314.1 - 1.8e-12 47.4 0.0 1.4e-09 38.1 0.0 2.2 2 0 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EPS28314.1 - 9.9e-09 35.3 2.6 1.2e-07 31.9 2.7 2.0 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 EPS28314.1 - 1.5e-05 24.5 0.1 2.5e-05 23.7 0.1 1.3 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 EPS28314.1 - 0.0011 18.2 1.0 0.0053 16.0 0.6 2.1 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_25 PF13481.6 EPS28314.1 - 0.0018 17.9 0.0 0.0033 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 EPS28314.1 - 0.0094 15.4 0.0 0.13 11.7 0.0 2.0 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF1610 PF07754.11 EPS28314.1 - 0.085 12.8 1.1 0.19 11.7 1.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) Ribosomal_S27e PF01667.17 EPS28314.1 - 0.086 12.6 0.2 0.18 11.5 0.2 1.5 1 0 0 1 1 1 0 Ribosomal protein S27 TRAUB PF08164.12 EPS28315.1 - 1.5e-29 102.3 2.7 2.2e-29 101.8 0.0 2.7 3 0 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.6 EPS28315.1 - 3.6e-28 99.0 1.0 3.6e-28 99.0 1.0 2.7 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor DUF4965 PF16335.5 EPS28316.1 - 8e-68 227.5 0.0 1.3e-67 226.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF5127 PF17168.4 EPS28316.1 - 8e-60 202.4 0.0 1.4e-59 201.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF1793 PF08760.11 EPS28316.1 - 4.9e-46 157.2 0.1 1e-45 156.2 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 EPS28316.1 - 2.9e-10 39.5 0.1 6e-10 38.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Glyco_hydr_116N PF12215.8 EPS28316.1 - 6.3e-05 22.6 0.0 0.00011 21.8 0.0 1.4 1 0 0 1 1 1 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term DUF2433 PF10360.9 EPS28317.1 - 5.1e-48 162.3 0.0 8.7e-48 161.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos PF00149.28 EPS28317.1 - 0.0008 20.0 0.0 0.002 18.7 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EPS28317.1 - 0.0009 19.5 0.0 0.0034 17.6 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PAP1 PF08601.10 EPS28318.1 - 2e-139 465.5 32.0 1e-138 463.1 17.0 2.5 2 1 1 3 3 3 2 Transcription factor PAP1 bZIP_1 PF00170.21 EPS28318.1 - 7.1e-08 32.4 11.2 1.5e-07 31.4 11.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor ERM PF00769.19 EPS28318.1 - 0.00019 21.4 2.2 0.00019 21.4 2.2 1.9 2 0 0 2 2 2 1 Ezrin/radixin/moesin family SHE3 PF17078.5 EPS28318.1 - 0.0024 17.6 4.1 0.0043 16.8 4.1 1.3 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 Spc29 PF17082.5 EPS28318.1 - 0.0053 16.6 3.3 0.0053 16.6 3.3 2.2 2 0 0 2 2 2 1 Spindle Pole Component 29 SlyX PF04102.12 EPS28318.1 - 0.0085 16.7 0.6 0.022 15.4 0.6 1.7 1 0 0 1 1 1 1 SlyX bZIP_Maf PF03131.17 EPS28318.1 - 0.014 15.9 10.7 0.037 14.5 10.7 1.7 1 0 0 1 1 1 0 bZIP Maf transcription factor TolA_bind_tri PF16331.5 EPS28318.1 - 0.079 13.1 2.7 0.26 11.4 2.7 1.9 1 0 0 1 1 1 0 TolA binding protein trimerisation MbeD_MobD PF04899.12 EPS28318.1 - 0.09 12.9 1.9 0.21 11.7 1.9 1.6 1 0 0 1 1 1 0 MbeD/MobD like DUF16 PF01519.16 EPS28318.1 - 0.15 12.5 3.7 0.084 13.4 1.4 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF16 HAUS-augmin3 PF14932.6 EPS28318.1 - 0.16 11.5 4.9 0.33 10.5 4.9 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 bZIP_2 PF07716.15 EPS28318.1 - 0.17 12.0 14.1 0.86 9.7 14.1 2.1 1 1 0 1 1 1 0 Basic region leucine zipper DUF2514 PF10721.9 EPS28318.1 - 0.42 10.6 3.9 0.8 9.7 3.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) EMP24_GP25L PF01105.24 EPS28318.1 - 1.3 9.0 3.1 0.88 9.5 1.3 1.6 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Tudor_3 PF18115.1 EPS28319.1 - 9.6e-09 35.0 0.0 1.7e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain LBR_tudor PF09465.10 EPS28319.1 - 0.00083 19.1 0.0 0.0024 17.6 0.0 1.8 2 0 0 2 2 2 1 Lamin-B receptor of TUDOR domain DUF4537 PF15057.6 EPS28319.1 - 0.0021 18.1 0.0 0.004 17.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) TUDOR PF00567.24 EPS28319.1 - 0.0056 16.7 0.0 0.11 12.5 0.0 2.2 2 0 0 2 2 2 1 Tudor domain Fis1_TPR_C PF14853.6 EPS28319.1 - 0.025 14.6 0.2 0.047 13.8 0.2 1.4 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat SKA1 PF07160.12 EPS28319.1 - 0.047 13.5 1.7 0.09 12.6 1.7 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DUF2730 PF10805.8 EPS28319.1 - 0.054 13.6 1.4 0.088 12.9 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) IL11 PF07400.11 EPS28319.1 - 0.13 11.9 0.8 0.22 11.2 0.1 1.7 2 0 0 2 2 2 0 Interleukin 11 NPC1_N PF16414.5 EPS28320.1 - 2.6e-84 282.6 1.9 3.7e-84 282.1 1.9 1.2 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Patched PF02460.18 EPS28320.1 - 1.8e-79 267.8 11.5 1.9e-78 264.4 11.5 2.0 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.8 EPS28320.1 - 1.4e-51 174.3 6.9 1.4e-51 174.3 6.9 3.2 3 1 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 EPS28320.1 - 1.1e-05 24.5 11.2 1.1e-05 24.5 11.2 3.7 3 1 0 3 3 3 1 MMPL family Folate_rec PF03024.14 EPS28320.1 - 0.0073 16.2 2.5 0.014 15.3 2.5 1.4 1 0 0 1 1 1 1 Folate receptor family HEAT_2 PF13646.6 EPS28321.1 - 9.6e-20 70.8 10.4 2.3e-05 24.7 0.0 8.4 7 2 2 9 9 8 6 HEAT repeats HEAT PF02985.22 EPS28321.1 - 3.2e-19 67.4 3.1 0.00026 21.0 0.1 10.2 11 0 0 11 11 10 3 HEAT repeat HEAT_EZ PF13513.6 EPS28321.1 - 4.9e-18 65.2 9.0 7.2e-08 32.8 0.0 9.0 9 1 0 10 10 9 2 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EPS28321.1 - 7.4e-13 48.9 0.1 0.21 12.2 0.0 6.7 5 1 1 6 6 6 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EPS28321.1 - 9.2e-12 45.3 0.8 0.0013 18.8 0.0 4.4 4 1 1 5 5 4 3 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 EPS28321.1 - 4.7e-11 42.4 0.7 1.7e-09 37.5 0.0 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain IFRD PF05004.13 EPS28321.1 - 2e-10 40.3 2.7 0.00033 19.9 1.4 4.0 3 1 1 4 4 4 2 Interferon-related developmental regulator (IFRD) CLASP_N PF12348.8 EPS28321.1 - 4.6e-07 29.6 0.1 0.0029 17.2 0.0 4.3 5 2 1 6 6 6 1 CLASP N terminal MMS19_C PF12460.8 EPS28321.1 - 1.1e-05 24.7 1.5 0.0057 15.8 0.0 3.6 3 0 0 3 3 3 1 RNAPII transcription regulator C-terminal RTP1_C1 PF10363.9 EPS28321.1 - 6.4e-05 23.1 0.9 3.7 7.8 0.0 5.3 4 1 1 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 UME PF08064.13 EPS28321.1 - 0.0001 22.2 0.0 0.062 13.2 0.1 4.5 3 2 1 4 4 4 1 UME (NUC010) domain Arm PF00514.23 EPS28321.1 - 0.00022 21.1 0.3 4.6 7.4 0.0 5.6 7 0 0 7 7 6 1 Armadillo/beta-catenin-like repeat RIX1 PF08167.12 EPS28321.1 - 0.001 18.9 0.0 0.14 11.9 0.0 3.5 3 1 0 3 3 3 1 rRNA processing/ribosome biogenesis Sec7_N PF12783.7 EPS28321.1 - 0.0018 18.2 0.1 0.029 14.3 0.0 3.0 2 1 1 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal ParcG PF10274.9 EPS28321.1 - 0.0022 18.2 0.8 0.054 13.6 0.3 3.1 3 0 0 3 3 3 1 Parkin co-regulated protein Adaptin_N PF01602.20 EPS28321.1 - 0.0024 16.5 0.8 0.58 8.6 0.0 3.7 3 1 0 3 3 3 1 Adaptin N terminal region DUF3535 PF12054.8 EPS28321.1 - 0.015 14.6 0.1 0.88 8.7 0.0 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF3535) NUC173 PF08161.12 EPS28321.1 - 0.034 13.8 1.8 24 4.5 0.0 5.6 7 1 0 7 7 7 0 NUC173 domain UNC45-central PF11701.8 EPS28321.1 - 0.042 13.8 2.6 0.37 10.7 1.0 3.3 2 1 1 3 3 3 0 Myosin-binding striated muscle assembly central DUF4042 PF13251.6 EPS28321.1 - 0.066 12.9 1.0 0.58 9.8 0.1 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4042) NopRA1 PF16201.5 EPS28321.1 - 0.073 12.6 0.1 8.7 5.9 0.0 3.5 2 1 1 3 3 3 0 Nucleolar pre-ribosomal-associated protein 1 Zn_clus PF00172.18 EPS28322.1 - 8.5e-09 35.4 12.8 1.7e-08 34.4 12.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPS28322.1 - 2.3e-07 30.1 0.8 7.3e-07 28.5 0.2 2.3 1 1 1 2 2 2 1 Fungal specific transcription factor domain Med7 PF05983.11 EPS28323.1 - 1.8e-62 210.9 5.1 2.3e-62 210.5 5.1 1.1 1 0 0 1 1 1 1 MED7 protein BRE1 PF08647.11 EPS28323.1 - 0.012 15.6 5.3 0.012 15.6 5.3 1.9 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase EcoEI_R_C PF08463.10 EPS28323.1 - 0.075 13.1 1.0 0.45 10.6 0.2 2.6 3 1 0 3 3 3 0 EcoEI R protein C-terminal PAP2 PF01569.21 EPS28324.1 - 4.3e-27 94.5 1.2 4.3e-27 94.5 1.2 1.8 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 EPS28324.1 - 0.014 15.1 8.6 0.069 12.8 8.6 2.2 1 1 0 1 1 1 0 PAP2 superfamily Fungal_trans_2 PF11951.8 EPS28325.1 - 4.1e-71 239.8 3.1 4.9e-71 239.6 3.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS28325.1 - 1.5e-07 31.4 8.5 3e-07 30.4 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2740 PF10872.8 EPS28325.1 - 0.15 11.9 0.0 0.4 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) F-actin_cap_A PF01267.17 EPS28327.1 - 1e-94 316.9 0.0 1.2e-94 316.7 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Endonuc-MspI PF09208.10 EPS28327.1 - 0.076 12.4 0.2 0.22 10.9 0.0 1.7 2 0 0 2 2 2 0 Restriction endonuclease MspI CCP_MauG PF03150.14 EPS28327.1 - 0.15 12.7 0.0 0.24 12.1 0.0 1.5 1 1 0 1 1 1 0 Di-haem cytochrome c peroxidase PEX11 PF05648.14 EPS28328.1 - 8.5e-38 130.0 0.0 9.7e-38 129.9 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) HET PF06985.11 EPS28329.1 - 0.00023 21.6 0.2 0.0063 16.9 0.2 2.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SET PF00856.28 EPS28334.1 - 0.0039 17.6 0.0 0.0045 17.4 0.0 1.2 1 0 0 1 1 1 1 SET domain 2-Hacid_dh_C PF02826.19 EPS28336.1 - 2.4e-46 157.3 0.0 4.4e-46 156.5 0.0 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EPS28336.1 - 3.1e-09 36.6 0.0 4.3e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EPS28336.1 - 0.03 14.5 0.0 0.067 13.4 0.0 1.6 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Acetyltransf_10 PF13673.7 EPS28337.1 - 1.1e-06 28.6 0.0 3.5e-06 27.0 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPS28337.1 - 3.4e-06 27.3 0.0 4.6e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EPS28337.1 - 3.7e-06 27.3 0.0 1e-05 25.8 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EPS28337.1 - 0.0027 17.8 0.0 0.0057 16.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPS28337.1 - 0.089 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Response_reg PF00072.24 EPS28340.1 - 7.1e-27 93.8 0.5 1.4e-26 92.8 0.5 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 EPS28340.1 - 1.5e-26 93.1 0.0 2.7e-26 92.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.25 EPS28340.1 - 1e-16 60.9 0.0 2.7e-10 40.2 0.0 2.6 2 0 0 2 2 2 2 PAS fold HisKA PF00512.25 EPS28340.1 - 2e-16 59.8 0.1 4.7e-16 58.6 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 EPS28340.1 - 8e-14 51.8 0.0 2.1e-12 47.2 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 EPS28340.1 - 2.1e-12 47.2 0.0 3.6e-07 30.4 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 EPS28340.1 - 0.0003 21.0 0.0 0.00075 19.7 0.0 1.7 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.7 EPS28340.1 - 0.0014 18.6 0.0 0.005 16.8 0.0 1.9 2 0 0 2 2 2 1 PAS domain MLTR_LBD PF17765.1 EPS28340.1 - 0.1 12.7 0.0 14 5.8 0.0 2.5 2 0 0 2 2 2 0 MmyB-like transcription regulator ligand binding domain Pro-kuma_activ PF09286.11 EPS28341.1 - 5.7e-46 156.4 0.0 1.1e-45 155.5 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EPS28341.1 - 3e-06 26.7 0.4 4.8e-06 26.0 0.4 1.2 1 0 0 1 1 1 1 Subtilase family AbiEi_3_N PF17194.4 EPS28341.1 - 0.21 11.6 0.1 0.65 10.1 0.0 1.8 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain Aldo_ket_red PF00248.21 EPS28342.1 - 3.2e-38 131.6 0.0 1.8e-37 129.1 0.0 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family Lipase_GDSL_2 PF13472.6 EPS28343.1 - 1.9e-15 57.7 2.1 2.4e-15 57.4 2.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EPS28343.1 - 2.8e-05 24.2 0.4 3.9e-05 23.7 0.4 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glyco_trans_2_3 PF13632.6 EPS28344.1 - 4.5e-52 176.8 1.5 4.5e-52 176.8 1.5 2.3 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EPS28344.1 - 0.008 16.0 0.1 0.025 14.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_hydro_16 PF00722.21 EPS28345.1 - 5.5e-17 61.8 4.2 9.1e-17 61.1 4.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 WSC PF01822.19 EPS28346.1 - 4.7e-33 113.2 27.2 6.7e-18 64.7 11.9 3.2 3 1 0 3 3 3 2 WSC domain Chitin_bind_1 PF00187.19 EPS28346.1 - 1.1e-07 32.2 23.9 1.1e-07 32.2 23.9 5.4 4 3 2 6 6 6 1 Chitin recognition protein Cutinase PF01083.22 EPS28348.1 - 2.9e-44 151.1 0.7 3.7e-44 150.8 0.7 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 EPS28348.1 - 0.0019 17.8 0.1 0.0034 17.0 0.1 1.4 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.11 EPS28348.1 - 0.0069 16.3 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) TPIP1 PF15338.6 EPS28348.1 - 0.024 14.7 0.1 0.051 13.6 0.1 1.5 1 0 0 1 1 1 0 p53-regulated apoptosis-inducing protein 1 Defensin_big PF14862.6 EPS28348.1 - 0.075 13.4 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 Big defensin CFEM PF05730.11 EPS28349.1 - 3.8e-13 49.3 6.4 4.4e-13 49.1 6.4 1.2 1 0 0 1 1 1 1 CFEM domain Glyco_hydro_25 PF01183.20 EPS28350.1 - 2e-41 142.2 0.2 2.3e-41 142.0 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Fungal_trans PF04082.18 EPS28352.1 - 1.9e-23 82.8 0.4 5.8e-23 81.3 0.0 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS28352.1 - 9.8e-10 38.4 9.5 1.9e-09 37.5 9.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2722 PF10846.8 EPS28352.1 - 0.061 12.3 6.6 0.096 11.6 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 EPS28352.1 - 3.1 7.7 15.9 5.6 6.9 15.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1993 PF09351.10 EPS28353.1 - 2.3e-60 203.4 0.1 2.6e-60 203.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) ETC_C1_NDUFA4 PF04800.12 EPS28353.1 - 0.11 12.7 0.1 2.9 8.2 0.1 2.2 2 0 0 2 2 2 0 ETC complex I subunit conserved region Amidohydro_1 PF01979.20 EPS28354.1 - 4.4e-58 197.2 0.0 5.4e-58 196.9 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EPS28354.1 - 5.9e-09 35.9 0.1 1.1e-05 25.1 0.0 2.3 2 1 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 EPS28354.1 - 0.0013 18.2 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase OPT PF03169.15 EPS28355.1 - 2.9e-165 551.4 51.9 3.3e-165 551.2 51.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein IQ PF00612.27 EPS28356.1 - 0.00085 18.9 1.2 0.0026 17.4 1.2 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif NAD_binding_4 PF07993.12 EPS28358.1 - 1.3e-32 113.0 0.0 3.2e-32 111.7 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.28 EPS28358.1 - 3.1e-32 111.7 0.0 6.7e-32 110.6 0.0 1.4 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 EPS28358.1 - 1.6e-13 50.7 0.0 2.6e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EPS28358.1 - 4.8e-08 33.2 0.0 1.4e-07 31.8 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.17 EPS28358.1 - 0.0029 16.7 0.0 0.077 12.1 0.0 2.3 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EPS28358.1 - 0.012 14.7 0.0 0.026 13.6 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EPS28358.1 - 0.027 13.5 0.0 0.049 12.6 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family YpjP PF14005.6 EPS28359.1 - 0.022 14.8 1.1 0.023 14.7 1.1 1.1 1 0 0 1 1 1 0 YpjP-like protein RseA_N PF03872.13 EPS28359.1 - 0.52 10.8 2.6 5.5 7.5 2.6 2.0 1 1 0 1 1 1 0 Anti sigma-E protein RseA, N-terminal domain DUF3439 PF11921.8 EPS28359.1 - 0.81 9.7 10.9 0.87 9.6 10.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 EPS28359.1 - 0.93 7.4 6.2 0.96 7.3 6.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mor PF08765.11 EPS28359.1 - 2.1 8.4 4.8 7.8 6.5 4.6 1.9 1 1 0 1 1 1 0 Mor transcription activator family NmrA PF05368.13 EPS28361.1 - 0.00062 19.4 0.1 0.00085 18.9 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family BNR PF02012.20 EPS28362.1 - 0.085 12.9 2.0 0.14 12.2 0.5 2.3 2 0 0 2 2 2 0 BNR/Asp-box repeat Sugar_tr PF00083.24 EPS28363.1 - 1.7e-88 297.5 26.2 2.1e-88 297.2 26.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS28363.1 - 1.4e-13 50.5 39.3 2.7e-13 49.6 25.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CBM_4_9 PF02018.17 EPS28364.1 - 0.0006 20.1 2.0 0.0012 19.1 0.2 2.0 2 0 0 2 2 2 1 Carbohydrate binding domain Sugar_tr PF00083.24 EPS28365.1 - 4.9e-114 381.7 20.4 6.4e-114 381.3 20.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS28365.1 - 5.2e-21 74.9 37.9 2.6e-14 52.9 20.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Acetyltransf_3 PF13302.7 EPS28366.1 - 1.7e-28 100.0 0.0 2.6e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPS28366.1 - 9.3e-05 22.6 0.0 0.00014 22.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Sugar_tr PF00083.24 EPS28367.1 - 4.6e-111 371.9 25.4 5.5e-111 371.6 25.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS28367.1 - 1.5e-20 73.4 28.0 1.5e-20 73.4 28.0 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily F-box-like PF12937.7 EPS28369.1 - 2.8e-06 27.1 0.5 6.5e-06 26.0 0.5 1.7 1 0 0 1 1 1 1 F-box-like F-box_5 PF18511.1 EPS28369.1 - 0.0034 16.9 0.0 0.0076 15.8 0.0 1.6 1 0 0 1 1 1 1 F-box Redoxin PF08534.10 EPS28370.1 - 3.8e-37 127.3 0.0 4.2e-37 127.1 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EPS28370.1 - 6.7e-12 45.4 0.0 8.6e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Stirrup PF09061.6 EPS28370.1 - 0.051 13.8 0.0 0.48 10.7 0.0 2.2 2 0 0 2 2 2 0 Stirrup ADH_N PF08240.12 EPS28371.1 - 1.6e-23 82.6 2.2 3e-23 81.8 2.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPS28371.1 - 2.4e-16 59.9 0.0 3.9e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EPS28371.1 - 7.5e-06 25.4 0.3 1.3e-05 24.6 0.3 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EPS28371.1 - 7.8e-05 22.1 0.3 0.00012 21.5 0.3 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EPS28371.1 - 0.014 15.3 0.1 0.021 14.7 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EPS28371.1 - 0.022 14.9 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.21 EPS28371.1 - 0.06 12.7 0.9 0.095 12.0 0.9 1.2 1 0 0 1 1 1 0 ThiF family NAD_binding_7 PF13241.6 EPS28371.1 - 0.062 13.8 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding GFO_IDH_MocA PF01408.22 EPS28371.1 - 0.15 12.9 0.0 0.3 11.9 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold MFS_1 PF07690.16 EPS28372.1 - 3.9e-30 105.0 35.9 2.7e-29 102.2 37.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 EPS28372.1 - 3.4e-05 23.3 15.5 0.00024 20.5 6.6 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Orf78 PF06024.12 EPS28372.1 - 0.0035 17.6 0.1 0.0077 16.5 0.1 1.5 1 0 0 1 1 1 1 Orf78 (ac78) DUF5367 PF17329.2 EPS28372.1 - 1.6 8.9 6.9 0.29 11.3 0.5 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5367) UL40 PF10682.9 EPS28373.1 - 1.3 8.7 4.4 29 4.2 0.2 2.9 1 1 2 3 3 3 0 Glycoprotein of human cytomegalovirus HHV-5 Pheromone PF08015.11 EPS28374.1 - 2.7 9.1 6.7 7.1 7.7 6.7 1.8 1 1 0 1 1 1 0 Fungal mating-type pheromone Pyr_redox_3 PF13738.6 EPS28376.1 - 6.5e-15 55.2 0.0 3.1e-14 52.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EPS28376.1 - 1.6e-12 46.7 0.0 4.2e-12 45.3 0.0 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EPS28376.1 - 5.6e-12 45.5 0.1 7.8e-11 41.7 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EPS28376.1 - 1.3e-08 34.4 0.0 1.9e-07 30.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPS28376.1 - 5.9e-06 26.4 0.1 1.7e-05 24.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EPS28376.1 - 0.00013 21.3 0.4 0.00028 20.2 0.1 1.7 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 EPS28376.1 - 0.0079 14.9 0.8 1.6 7.4 0.1 2.8 3 0 0 3 3 3 2 HI0933-like protein NAD_binding_9 PF13454.6 EPS28376.1 - 0.049 13.6 1.4 0.42 10.6 0.3 2.4 2 1 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 EPS28376.1 - 0.053 12.9 1.7 0.38 10.0 0.2 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EPS28376.1 - 0.084 11.9 0.3 1 8.4 0.2 2.1 2 0 0 2 2 2 0 FAD binding domain Bim_N PF06773.11 EPS28376.1 - 0.18 11.5 0.1 0.54 10.0 0.1 1.8 1 0 0 1 1 1 0 Bim protein N-terminus DUF4815 PF16075.5 EPS28377.1 - 0.062 11.6 0.0 0.14 10.4 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4815) DUF5385 PF17359.2 EPS28377.1 - 0.094 12.3 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5385) zf-C2H2 PF00096.26 EPS28378.1 - 9.2e-12 44.7 10.0 1.5e-05 25.1 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPS28378.1 - 8.6e-09 35.5 8.4 0.0011 19.6 0.4 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EPS28378.1 - 2.6e-07 30.7 9.8 2.4e-05 24.6 1.8 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-H2C2_5 PF13909.6 EPS28378.1 - 0.00022 20.9 6.7 0.064 13.0 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.6 EPS28378.1 - 0.0074 16.3 4.7 1.4 9.0 0.5 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EPS28378.1 - 0.0092 16.2 0.1 0.0092 16.2 0.1 3.1 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 EPS28378.1 - 0.068 13.6 7.3 1.6 9.2 1.4 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_11 PF16622.5 EPS28378.1 - 0.16 11.8 2.6 4.1 7.2 0.2 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-met PF12874.7 EPS28378.1 - 0.48 10.9 0.1 0.48 10.9 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type HNH_5 PF14279.6 EPS28378.1 - 0.85 9.5 3.3 4.1 7.3 0.2 2.4 2 0 0 2 2 2 0 HNH endonuclease zf-AN1 PF01428.16 EPS28378.1 - 6.2 7.1 7.8 18 5.6 1.8 2.3 1 1 1 2 2 2 0 AN1-like Zinc finger DLH PF01738.18 EPS28382.1 - 6.3e-16 58.6 0.0 7.5e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Zn_clus PF00172.18 EPS28385.1 - 3.5e-08 33.4 6.5 5.2e-08 32.9 6.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GATA PF00320.27 EPS28388.1 - 1.3e-16 59.9 2.3 3.3e-16 58.6 2.3 1.7 1 0 0 1 1 1 1 GATA zinc finger AreA_N PF07573.11 EPS28388.1 - 5.8e-15 55.7 4.1 5.8e-15 55.7 4.1 4.4 3 2 0 3 3 3 1 Nitrogen regulatory protein AreA N terminus DUF1752 PF08550.10 EPS28388.1 - 8.5e-13 47.9 2.4 1.7e-12 47.0 2.4 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) HSP9_HSP12 PF04119.12 EPS28390.1 - 0.00037 20.8 1.2 0.037 14.4 0.2 2.4 2 1 1 3 3 3 3 Heat shock protein 9/12 Ipi1_N PF12333.8 EPS28391.1 - 6.6e-27 94.1 0.2 2.7e-26 92.1 0.0 2.1 2 1 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation MMS19_C PF12460.8 EPS28391.1 - 0.0057 15.8 1.1 0.0088 15.2 0.3 1.7 1 1 0 1 1 1 1 RNAPII transcription regulator C-terminal HEAT_2 PF13646.6 EPS28391.1 - 0.044 14.2 0.2 0.12 12.8 0.2 1.7 1 0 0 1 1 1 0 HEAT repeats HEAT_EZ PF13513.6 EPS28391.1 - 0.24 12.0 4.6 5.5 7.6 0.3 3.2 3 0 0 3 3 3 0 HEAT-like repeat HEAT PF02985.22 EPS28391.1 - 0.25 11.7 2.5 3.4 8.2 0.2 3.3 3 0 0 3 3 3 0 HEAT repeat MFMR PF07777.11 EPS28391.1 - 0.35 11.4 1.2 0.73 10.4 0.0 2.1 2 0 0 2 2 2 0 G-box binding protein MFMR Transp_cyt_pur PF02133.15 EPS28393.1 - 3.4e-86 289.8 41.7 4.1e-86 289.5 41.7 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Pyrid_oxidase_2 PF13883.6 EPS28394.1 - 1.1e-33 116.6 0.0 1.5e-33 116.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Cyclin PF08613.11 EPS28395.1 - 2.3e-05 24.8 4.0 2.4e-05 24.8 0.0 2.5 3 0 0 3 3 3 1 Cyclin Cyclin_N PF00134.23 EPS28395.1 - 0.0066 16.2 0.1 0.013 15.2 0.1 1.5 1 1 0 1 1 1 1 Cyclin, N-terminal domain Aminotran_5 PF00266.19 EPS28398.1 - 3.1e-56 190.9 0.0 6.5e-56 189.9 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EPS28398.1 - 8e-09 35.1 0.0 1.4e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EPS28398.1 - 0.00012 20.8 0.0 0.00018 20.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme HTH_AsnC-type PF13404.6 EPS28398.1 - 0.048 13.5 0.1 4.3 7.2 0.0 3.4 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain DEAD_assoc PF08494.11 EPS28398.1 - 0.087 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 DEAD/H associated Glyco_hydro_47 PF01532.20 EPS28398.1 - 0.13 11.1 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 47 Robl_LC7 PF03259.17 EPS28399.1 - 1.3e-05 24.8 0.8 0.052 13.3 0.0 3.0 3 0 0 3 3 3 2 Roadblock/LC7 domain bZIP_2 PF07716.15 EPS28400.1 - 2.4 8.3 5.8 0.64 10.2 0.9 2.3 2 0 0 2 2 2 0 Basic region leucine zipper SEN1_N PF12726.7 EPS28401.1 - 5.8e-210 699.4 11.4 7.2e-210 699.0 11.4 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 EPS28401.1 - 8.9e-73 245.3 0.6 8.9e-73 245.3 0.6 2.1 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.6 EPS28401.1 - 2.1e-60 203.8 0.0 7.8e-60 201.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EPS28401.1 - 2e-11 43.9 0.0 1.2e-06 28.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.21 EPS28401.1 - 5.9e-08 32.6 0.4 2.4e-06 27.3 0.0 2.6 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 EPS28401.1 - 6.8e-08 33.0 0.0 4.9e-07 30.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EPS28401.1 - 9.6e-07 28.8 0.1 0.02 14.7 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 EPS28401.1 - 0.00037 20.3 0.1 0.0064 16.3 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EPS28401.1 - 0.0016 18.7 0.0 0.013 15.8 0.0 2.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EPS28401.1 - 0.006 15.7 0.2 0.031 13.3 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein ResIII PF04851.15 EPS28401.1 - 0.053 13.5 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_16 PF13191.6 EPS28401.1 - 0.058 13.8 0.1 0.24 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Helicase_RecD PF05127.14 EPS28401.1 - 0.061 13.2 0.0 1.5 8.6 0.0 2.6 2 0 0 2 2 2 0 Helicase FtsK_SpoIIIE PF01580.18 EPS28401.1 - 0.063 12.6 0.0 0.23 10.8 0.0 1.9 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.6 EPS28401.1 - 0.083 13.4 0.9 0.25 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EPS28401.1 - 0.095 12.5 0.2 0.25 11.1 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF1981 PF09324.10 EPS28401.1 - 0.15 11.9 0.1 0.53 10.2 0.0 2.0 2 0 0 2 2 1 0 Domain of unknown function (DUF1981) DUF863 PF05904.11 EPS28402.1 - 0.055 11.9 0.0 0.067 11.6 0.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF863) PhoLip_ATPase_C PF16212.5 EPS28403.1 - 1.5e-80 270.6 24.1 1.5e-80 270.6 24.1 2.3 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EPS28403.1 - 2e-19 69.0 1.9 6.2e-19 67.5 1.9 1.8 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EPS28403.1 - 4.9e-12 45.8 0.0 2.7e-11 43.4 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EPS28403.1 - 1.1e-10 42.2 3.2 6.4e-07 29.9 0.7 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EPS28403.1 - 0.0006 19.4 1.5 0.0074 15.8 0.0 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EPS28403.1 - 0.0086 15.8 0.3 0.028 14.2 0.3 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase FtsX PF02687.21 EPS28403.1 - 4.4 7.9 10.7 0.87 10.1 2.1 3.0 3 0 0 3 3 3 0 FtsX-like permease family AA_permease_C PF13906.6 EPS28403.1 - 7.6 6.7 10.7 1.1 9.4 5.6 2.4 2 0 0 2 2 2 0 C-terminus of AA_permease vATP-synt_E PF01991.18 EPS28405.1 - 1.3e-62 210.8 10.6 1.5e-62 210.6 10.6 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Med3 PF11593.8 EPS28405.1 - 0.027 13.7 0.2 0.031 13.5 0.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Bap31_Bap29_C PF18035.1 EPS28405.1 - 0.084 12.9 0.2 0.084 12.9 0.2 2.2 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Mg_trans_NIPA PF05653.14 EPS28406.1 - 6.3e-14 51.8 12.6 6.8e-09 35.2 3.4 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 EPS28406.1 - 4.1e-06 27.0 1.0 4.1e-06 27.0 1.0 2.9 3 0 0 3 3 3 2 EamA-like transporter family PUNUT PF16913.5 EPS28406.1 - 0.0023 17.2 4.9 0.0023 17.2 4.9 3.0 3 1 0 3 3 3 1 Purine nucleobase transmembrane transport Multi_Drug_Res PF00893.19 EPS28406.1 - 1.7 9.4 7.9 14 6.5 2.1 2.9 2 1 0 2 2 2 0 Small Multidrug Resistance protein SRF-TF PF00319.18 EPS28407.1 - 3.3e-21 74.5 0.1 4.9e-21 74.0 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF604 PF04646.12 EPS28408.1 - 7.3e-06 25.6 0.0 1.2e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.16 EPS28408.1 - 0.0013 18.3 0.0 0.0027 17.2 0.0 1.5 1 1 0 1 1 1 1 Fringe-like GDI PF00996.18 EPS28410.1 - 3.2e-25 88.6 0.0 5.7e-14 51.5 0.0 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor NAD_binding_8 PF13450.6 EPS28410.1 - 0.048 13.9 0.0 0.23 11.7 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain B9-C2 PF07162.11 EPS28410.1 - 0.054 13.7 0.0 0.097 12.9 0.0 1.4 1 0 0 1 1 1 0 Ciliary basal body-associated, B9 protein Pro_isomerase PF00160.21 EPS28411.1 - 2.5e-54 183.8 0.1 2.8e-54 183.7 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_A22B PF04258.13 EPS28412.1 - 2.4e-61 207.8 3.0 7.8e-61 206.1 3.0 1.7 1 1 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 EPS28412.1 - 3e-05 23.6 6.7 4.2e-05 23.2 2.7 2.4 2 1 0 2 2 2 1 Signal-peptide peptidase, presenilin aspartyl protease RNase_PH PF01138.21 EPS28413.1 - 3e-13 50.4 0.9 6.7e-12 46.0 0.9 2.3 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 DUF5529 PF17669.1 EPS28413.1 - 0.057 13.5 1.3 0.085 12.9 0.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5529) NAD_binding_6 PF08030.12 EPS28414.1 - 5.1e-24 85.2 0.0 7.2e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EPS28414.1 - 5.1e-17 62.2 10.5 6.2e-17 61.9 7.2 2.6 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EPS28414.1 - 1.1e-13 51.2 0.0 3e-13 49.8 0.0 1.8 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 EPS28414.1 - 0.025 15.2 0.0 1.7 9.3 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Acetyltransf_1 PF00583.25 EPS28415.1 - 1.6e-05 25.1 0.0 0.00021 21.5 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EPS28415.1 - 0.0027 18.1 0.0 0.0045 17.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Sgf11 PF08209.11 EPS28416.1 - 4.1e-09 35.9 0.3 4.1e-09 35.9 0.3 1.8 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) Sgf11_N PF18519.1 EPS28416.1 - 0.073 12.6 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 SAGA-associated factor 11 N-terminal domain zf-C2HC5 PF06221.13 EPS28418.1 - 3.2e-22 78.3 6.4 5.1e-22 77.6 6.4 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type p450 PF00067.22 EPS28419.1 - 9e-67 225.8 0.0 1.1e-66 225.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sdh_cyt PF01127.22 EPS28419.1 - 0.041 13.9 0.9 0.099 12.7 0.9 1.6 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Mpv17_PMP22 PF04117.12 EPS28420.1 - 4.8e-13 49.1 0.0 1.1e-12 48.0 0.0 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family MFS_1 PF07690.16 EPS28421.1 - 5.9e-38 130.7 57.5 5.9e-38 130.7 57.5 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily THDPS_M PF14789.6 EPS28422.1 - 0.15 12.2 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase middle Aldo_ket_red PF00248.21 EPS28423.1 - 8.6e-74 248.4 0.0 9.8e-74 248.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Hexokinase_2 PF03727.16 EPS28424.1 - 3.6e-80 268.9 0.0 4.6e-80 268.5 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EPS28424.1 - 1.1e-71 240.9 0.0 1.6e-71 240.3 0.0 1.3 1 0 0 1 1 1 1 Hexokinase DUF948 PF06103.11 EPS28424.1 - 0.073 13.3 0.2 6.2 7.2 0.0 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1690 PF07956.11 EPS28425.1 - 4.6e-39 134.0 6.2 3.4e-19 69.7 0.1 2.0 2 0 0 2 2 2 2 Protein of Unknown function (DUF1690) FAM184 PF15665.5 EPS28425.1 - 0.087 12.6 4.9 1.6 8.5 2.9 2.2 2 0 0 2 2 2 0 Family with sequence similarity 184, A and B DUF3040 PF11239.8 EPS28425.1 - 0.26 11.6 1.5 0.56 10.5 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) POP1 PF06978.11 EPS28426.1 - 2.1e-74 249.9 20.2 3.9e-74 249.1 20.2 1.5 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 EPS28426.1 - 6.2e-32 109.8 0.8 2.8e-31 107.7 0.8 2.2 1 0 0 1 1 1 1 POPLD (NUC188) domain TRI12 PF06609.13 EPS28427.1 - 1.7e-33 116.0 33.0 1.9e-33 115.8 32.0 1.4 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 EPS28427.1 - 4.7e-13 48.8 65.9 3.3e-12 46.0 60.3 3.1 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS28427.1 - 4.1e-08 32.5 9.6 4.1e-08 32.5 9.6 3.6 2 1 1 3 3 3 2 Sugar (and other) transporter Cation_ATPase_C PF00689.21 EPS28427.1 - 0.023 14.4 5.0 0.045 13.4 3.6 2.4 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus 4HBT PF03061.22 EPS28428.1 - 2.9e-06 27.5 0.1 5.1e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily UCH PF00443.29 EPS28429.1 - 9e-50 169.6 0.2 1.2e-49 169.1 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EPS28429.1 - 4.8e-12 46.1 11.6 2.5e-11 43.7 11.6 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 EPS28429.1 - 1e-10 41.2 0.0 2.7e-10 39.9 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family ARPC4 PF05856.12 EPS28430.1 - 2.1e-76 255.2 3.0 2.3e-76 255.0 3.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) RRM_1 PF00076.22 EPS28431.1 - 3e-05 23.8 0.0 6.2e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2461 PF09365.10 EPS28432.1 - 3.2e-74 249.4 0.0 4.5e-74 248.9 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) CDC45 PF02724.14 EPS28432.1 - 0.71 8.1 5.9 1.1 7.5 5.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Raftlin PF15250.6 EPS28432.1 - 0.91 8.2 3.7 1.3 7.7 3.7 1.1 1 0 0 1 1 1 0 Raftlin Presenilin PF01080.17 EPS28432.1 - 3.4 6.3 6.9 4.9 5.8 6.9 1.1 1 0 0 1 1 1 0 Presenilin Zn_clus PF00172.18 EPS28433.1 - 1.1e-08 35.0 7.8 1.6e-08 34.5 7.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Telomere_reg-2 PF10193.9 EPS28434.1 - 0.11 12.9 0.0 0.15 12.6 0.0 1.1 1 0 0 1 1 1 0 Telomere length regulation protein MerT PF02411.15 EPS28434.1 - 0.18 11.8 0.0 0.28 11.2 0.0 1.2 1 0 0 1 1 1 0 MerT mercuric transport protein Pkinase PF00069.25 EPS28435.1 - 2.4e-68 230.4 0.0 1.2e-67 228.1 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS28435.1 - 2.8e-38 131.7 0.0 2.1e-36 125.5 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Fungal_KA1 PF16797.5 EPS28435.1 - 9.2e-38 128.6 0.4 2.2e-37 127.4 0.4 1.7 1 0 0 1 1 1 1 Fungal kinase associated-1 domain APH PF01636.23 EPS28435.1 - 0.00017 21.6 0.1 0.0096 15.9 0.1 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EPS28435.1 - 0.00017 20.6 0.0 0.0005 19.1 0.0 1.7 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EPS28435.1 - 0.0033 16.8 0.0 0.0068 15.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EPS28435.1 - 0.0044 16.4 0.0 0.0083 15.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 EPS28435.1 - 0.022 14.3 0.0 0.058 13.0 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Redoxin PF08534.10 EPS28436.1 - 1.1e-34 119.2 0.0 1.2e-34 119.1 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EPS28436.1 - 6.3e-14 52.0 0.0 8.1e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family WD40 PF00400.32 EPS28437.1 - 1.8e-08 34.9 15.8 0.0051 17.6 0.1 5.8 5 0 0 5 5 5 3 WD domain, G-beta repeat zf-C3HC4 PF00097.25 EPS28437.1 - 0.0032 17.3 1.5 0.0032 17.3 1.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RWD PF05773.22 EPS28437.1 - 0.049 13.9 0.0 0.14 12.4 0.0 1.7 2 0 0 2 2 2 0 RWD domain Zn_ribbon_17 PF17120.5 EPS28437.1 - 0.12 12.0 20.7 0.042 13.5 14.9 2.8 2 1 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_14 PF17978.1 EPS28437.1 - 0.16 12.4 1.8 0.34 11.4 1.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 EPS28437.1 - 0.78 10.1 10.1 0.028 14.8 3.7 2.0 2 0 0 2 2 2 0 Ring finger domain UQ_con PF00179.26 EPS28438.1 - 7.3e-47 158.5 0.0 8.3e-47 158.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EPS28438.1 - 0.0003 20.5 0.0 0.00038 20.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EPS28438.1 - 0.014 15.3 0.0 0.026 14.4 0.0 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 EPS28438.1 - 0.14 12.5 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 RWD domain WH1 PF00568.23 EPS28439.1 - 2.6e-30 104.6 0.0 3.5e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 EPS28439.1 - 0.023 14.5 2.8 0.076 12.9 2.8 1.9 1 1 0 1 1 1 0 WH2 motif DCP1 PF06058.13 EPS28439.1 - 0.033 14.1 0.0 0.048 13.6 0.0 1.2 1 0 0 1 1 1 0 Dcp1-like decapping family ERCC4 PF02732.15 EPS28441.1 - 5.8e-18 65.6 0.0 2.8e-17 63.3 0.0 2.2 2 0 0 2 2 2 1 ERCC4 domain HHH_5 PF14520.6 EPS28441.1 - 0.0024 18.5 0.0 0.0097 16.5 0.0 2.1 1 1 0 1 1 1 1 Helix-hairpin-helix domain DUF4780 PF16012.5 EPS28441.1 - 0.0051 16.3 0.0 19 4.7 0.0 3.4 3 0 0 3 3 3 2 Domain of unknown function (DUF4780) Peptidase_S41 PF03572.18 EPS28442.1 - 5.1e-11 42.4 0.0 9.9e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 eIF-1a PF01176.19 EPS28443.1 - 4.2e-22 77.7 0.0 5.9e-22 77.2 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 fn3_2 PF16893.5 EPS28445.1 - 7.7e-39 131.7 0.1 1.3e-38 131.0 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 EPS28445.1 - 1.6e-24 85.6 0.4 3e-24 84.7 0.4 1.5 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus PTCB-BRCT PF12738.7 EPS28445.1 - 2.2e-12 46.7 0.0 4.3e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 EPS28445.1 - 6.8e-08 32.8 0.0 1.2e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.8 EPS28445.1 - 2.6e-05 24.4 0.0 5.8e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) BRCT_2 PF16589.5 EPS28445.1 - 0.00043 20.6 0.0 0.00079 19.8 0.0 1.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain fn3 PF00041.21 EPS28445.1 - 0.00058 20.2 0.1 0.0018 18.6 0.1 1.8 1 1 0 1 1 1 1 Fibronectin type III domain Aminotran_1_2 PF00155.21 EPS28446.1 - 1.8e-75 254.4 0.0 2e-75 254.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Abhydrolase_3 PF07859.13 EPS28447.1 - 6.6e-59 199.3 0.0 8.8e-59 198.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EPS28447.1 - 0.013 15.0 0.0 0.25 10.8 0.0 2.1 1 1 0 1 1 1 0 Prolyl oligopeptidase family Esterase_phd PF10503.9 EPS28447.1 - 0.1 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase Lyase_1 PF00206.20 EPS28448.1 - 4.2e-110 368.0 0.0 6.1e-110 367.5 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 EPS28448.1 - 1e-20 73.9 0.0 3e-20 72.4 0.0 1.9 1 0 0 1 1 1 1 Fumarase C C-terminus Acetyltransf_10 PF13673.7 EPS28450.1 - 6.3e-08 32.6 0.0 9.5e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPS28450.1 - 8e-08 32.5 0.1 1.1e-07 32.1 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EPS28450.1 - 7.9e-07 29.4 0.1 1.1e-06 28.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ribosomal_L24e PF01246.20 EPS28451.1 - 1.3e-28 99.0 0.1 3.2e-28 97.7 0.1 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e DUF775 PF05603.12 EPS28451.1 - 0.027 14.0 1.9 0.034 13.7 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Metallophos PF00149.28 EPS28453.1 - 4.4e-30 105.7 0.5 8.4e-30 104.8 0.5 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 EPS28453.1 - 4.4e-15 56.3 0.1 1.5e-14 54.5 0.1 2.0 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 EPS28453.1 - 6e-13 49.2 0.2 2.2e-12 47.4 0.2 2.0 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain PhoD_N PF16655.5 EPS28453.1 - 0.015 15.9 0.1 0.038 14.5 0.1 1.7 1 0 0 1 1 1 0 PhoD-like phosphatase, N-terminal domain CorA PF01544.18 EPS28454.1 - 5.4e-08 32.5 0.1 9.2e-08 31.7 0.1 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Sporozoite_P67 PF05642.11 EPS28454.1 - 0.011 13.9 0.6 0.013 13.6 0.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ApoL PF05461.11 EPS28454.1 - 0.032 13.6 0.6 0.032 13.6 0.6 2.1 2 0 0 2 2 2 0 Apolipoprotein L DDE_Tnp_ISL3 PF01610.17 EPS28454.1 - 0.063 13.0 0.1 0.099 12.3 0.1 1.2 1 0 0 1 1 1 0 Transposase Melibiase_2 PF16499.5 EPS28455.1 - 3e-63 213.7 9.3 2.4e-62 210.7 9.3 2.1 1 1 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 EPS28455.1 - 6.9e-12 45.3 1.2 1.7e-08 34.4 0.0 3.1 3 0 0 3 3 3 2 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 EPS28455.1 - 5.2e-08 32.2 0.1 1.5e-06 27.4 0.0 2.1 2 0 0 2 2 2 2 Melibiase AdoMet_MTase PF07757.13 EPS28456.1 - 3.1e-36 124.1 0.0 6.4e-36 123.1 0.0 1.5 1 1 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Sec15 PF04091.12 EPS28456.1 - 0.16 11.3 0.0 0.33 10.3 0.0 1.4 2 0 0 2 2 2 0 Exocyst complex subunit Sec15-like His_Phos_1 PF00300.22 EPS28457.1 - 1.8e-35 122.4 0.5 8e-34 117.0 0.5 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF1246 PF06849.12 EPS28457.1 - 0.045 13.7 0.0 0.073 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1246) DASH_Hsk3 PF08227.11 EPS28458.1 - 1.7e-20 73.1 3.5 2.6e-20 72.5 3.5 1.3 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like FlxA PF14282.6 EPS28458.1 - 0.11 12.5 4.2 0.16 11.9 4.2 1.3 1 0 0 1 1 1 0 FlxA-like protein ApbA PF02558.16 EPS28460.1 - 3.6e-26 91.6 0.0 5.3e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 EPS28460.1 - 1.9e-20 73.3 0.0 3.1e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DEAD PF00270.29 EPS28462.1 - 8.7e-36 123.3 0.0 1.6e-35 122.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPS28462.1 - 4.2e-26 91.5 0.0 6e-24 84.5 0.1 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 EPS28462.1 - 1.9e-07 31.2 0.0 4e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Rpr2 PF04032.16 EPS28463.1 - 3.1e-23 81.9 0.4 3.1e-23 81.9 0.4 1.8 2 1 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain RPN2_C PF18004.1 EPS28463.1 - 0.022 14.7 0.3 0.022 14.7 0.3 1.7 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain DUF3342 PF11822.8 EPS28463.1 - 0.033 14.4 0.1 0.058 13.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) DZR PF12773.7 EPS28463.1 - 0.059 13.4 0.8 0.2 11.7 0.8 1.9 1 1 0 1 1 1 0 Double zinc ribbon DUF1664 PF07889.12 EPS28463.1 - 0.18 11.8 0.4 0.35 10.9 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Clr2 PF10383.9 EPS28464.1 - 0.12 13.1 0.0 0.13 13.0 0.0 1.1 1 0 0 1 1 1 0 Transcription-silencing protein Clr2 T3SSipB PF16535.5 EPS28465.1 - 0.013 16.0 0.3 0.02 15.4 0.0 1.4 2 0 0 2 2 2 0 Type III cell invasion protein SipB DUF1664 PF07889.12 EPS28465.1 - 0.017 15.1 0.7 0.082 12.9 0.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 EPS28465.1 - 0.026 14.7 1.0 0.061 13.5 1.0 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Fzo_mitofusin PF04799.13 EPS28465.1 - 0.044 13.3 0.2 0.084 12.4 0.2 1.5 1 1 0 1 1 1 0 fzo-like conserved region SPATA24 PF15175.6 EPS28465.1 - 0.074 13.0 0.4 0.074 13.0 0.4 1.4 2 0 0 2 2 2 0 Spermatogenesis-associated protein 24 HSCB_C PF07743.13 EPS28465.1 - 0.08 13.4 0.5 0.86 10.1 0.0 2.2 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain PhaP_Bmeg PF09602.10 EPS28465.1 - 0.14 12.1 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Vps51 PF08700.11 EPS28465.1 - 0.16 12.1 1.5 7 6.8 0.8 2.8 1 1 1 2 2 2 0 Vps51/Vps67 TolA_bind_tri PF16331.5 EPS28465.1 - 4.5 7.4 13.6 2.1 8.5 0.7 3.3 3 1 0 3 3 3 0 TolA binding protein trimerisation Wbp11 PF09429.10 EPS28466.1 - 3.9e-21 75.2 14.8 3.9e-21 75.2 14.8 2.5 2 1 1 3 3 3 1 WW domain binding protein 11 ECH_1 PF00378.20 EPS28467.1 - 3.2e-50 170.8 0.0 3.9e-50 170.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EPS28467.1 - 7.7e-28 97.9 0.0 8.8e-25 87.9 0.1 2.4 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Acetyltransf_8 PF13523.6 EPS28468.1 - 5.9e-41 139.5 0.1 9.7e-41 138.8 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ABC_membrane PF00664.23 EPS28469.1 - 5.1e-93 311.7 22.5 5.2e-52 177.2 4.3 2.5 2 1 1 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 EPS28469.1 - 1.1e-60 204.1 0.0 1.7e-30 106.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EPS28469.1 - 2.3e-17 63.2 0.5 2.3e-05 24.0 0.0 4.4 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EPS28469.1 - 1.1e-08 35.7 2.0 0.0012 19.2 0.0 3.4 3 2 0 3 3 2 2 AAA ATPase domain AAA_29 PF13555.6 EPS28469.1 - 3.3e-08 33.2 0.2 0.0059 16.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EPS28469.1 - 1.1e-07 32.2 2.2 0.18 12.1 0.2 4.3 2 2 0 3 3 3 2 AAA domain AAA_30 PF13604.6 EPS28469.1 - 2.7e-05 24.0 0.9 0.058 13.1 0.0 3.7 3 1 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 EPS28469.1 - 5.3e-05 23.2 0.0 0.16 11.9 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 EPS28469.1 - 0.00013 22.6 0.6 0.93 10.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA PF00004.29 EPS28469.1 - 0.00013 22.4 1.7 2.6 8.5 0.3 4.3 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 EPS28469.1 - 0.00017 20.5 0.0 0.0036 16.1 0.0 2.3 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_25 PF13481.6 EPS28469.1 - 0.0002 21.0 0.2 1.5 8.3 0.0 3.9 4 0 0 4 4 4 2 AAA domain AAA_5 PF07728.14 EPS28469.1 - 0.00094 19.2 0.0 1.4 8.9 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EPS28469.1 - 0.0012 19.1 0.1 2.3 8.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.17 EPS28469.1 - 0.0013 18.9 0.0 0.39 10.8 0.0 2.5 2 0 0 2 2 2 1 Helicase HerA, central domain SbcCD_C PF13558.6 EPS28469.1 - 0.0038 17.4 0.2 5.2 7.4 0.0 3.3 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 EPS28469.1 - 0.0065 17.0 0.0 2.4 8.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EPS28469.1 - 0.0072 15.6 0.0 2.4 7.4 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_21 PF13304.6 EPS28469.1 - 0.0081 16.0 0.8 0.31 10.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_7 PF12775.7 EPS28469.1 - 0.011 15.3 0.0 4 6.9 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region APS_kinase PF01583.20 EPS28469.1 - 0.014 15.3 0.0 4.6 7.1 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase DEAD PF00270.29 EPS28469.1 - 0.016 15.0 0.1 0.25 11.1 0.0 2.7 3 1 0 3 3 3 0 DEAD/DEAH box helicase DUF3987 PF13148.6 EPS28469.1 - 0.029 13.4 0.0 2.6 7.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Cad PF03596.13 EPS28469.1 - 0.03 14.2 3.7 0.11 12.4 0.3 2.7 2 0 0 2 2 2 0 Cadmium resistance transporter G-alpha PF00503.20 EPS28469.1 - 0.032 13.4 0.0 4.3 6.4 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit TniB PF05621.11 EPS28469.1 - 0.037 13.5 0.0 37 3.6 0.0 3.9 4 0 0 4 4 4 0 Bacterial TniB protein NB-ARC PF00931.22 EPS28469.1 - 0.039 13.1 0.0 9.3 5.3 0.0 2.5 3 0 0 3 3 2 0 NB-ARC domain MMR_HSR1 PF01926.23 EPS28469.1 - 0.057 13.5 0.0 7.9 6.6 0.0 2.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_15 PF13175.6 EPS28469.1 - 0.068 12.9 0.0 4 7.0 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain SRP54 PF00448.22 EPS28469.1 - 0.075 12.7 0.2 19 4.8 0.0 3.0 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 EPS28469.1 - 0.098 12.4 0.1 10 5.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain KdpD PF02702.17 EPS28469.1 - 0.1 12.1 0.1 11 5.4 0.1 2.4 2 0 0 2 2 2 0 Osmosensitive K+ channel His kinase sensor domain AAA_17 PF13207.6 EPS28469.1 - 0.33 11.4 1.2 51 4.3 0.1 3.1 3 0 0 3 3 3 0 AAA domain DUF3671 PF12420.8 EPS28469.1 - 0.38 10.8 2.1 0.59 10.2 0.1 2.4 2 0 0 2 2 1 0 Protein of unknown function AMP-binding PF00501.28 EPS28470.1 - 2.4e-75 253.7 0.0 5.7e-67 226.1 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 EPS28470.1 - 9.7e-69 232.2 0.0 1.2e-34 119.8 0.0 2.5 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.25 EPS28470.1 - 1.3e-25 89.5 0.2 3.5e-12 46.5 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site Spore_III_AB PF09548.10 EPS28470.1 - 0.16 12.1 0.8 5.9 7.0 0.1 3.2 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) DUF1749 PF08538.10 EPS28471.1 - 1.1e-98 330.0 0.0 1.4e-98 329.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_1 PF00561.20 EPS28471.1 - 0.00043 20.0 0.2 0.00096 18.9 0.1 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPS28471.1 - 0.0009 19.9 0.0 0.0013 19.4 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPS28471.1 - 0.042 13.1 0.0 0.072 12.3 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF900 PF05990.12 EPS28471.1 - 0.054 13.0 0.0 0.13 11.7 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.13 EPS28471.1 - 0.088 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Pkinase PF00069.25 EPS28472.1 - 6.7e-55 186.3 2.6 9.6e-35 120.2 0.0 2.5 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EPS28472.1 - 1.5e-36 126.1 0.0 2e-25 89.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EPS28472.1 - 0.0052 16.1 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EPS28472.1 - 0.09 12.7 1.1 0.7 9.8 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF3896 PF13035.6 EPS28472.1 - 3.3 7.9 7.1 0.49 10.6 0.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3896) BTB PF00651.31 EPS28473.1 - 2.6e-26 92.0 0.0 7.6e-14 51.9 0.1 2.7 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.6 EPS28473.1 - 1.3e-07 32.0 0.0 1.6e-06 28.5 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EPS28473.1 - 1.4e-06 28.4 0.1 5.1e-06 26.7 0.1 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EPS28473.1 - 2.9e-06 27.8 0.1 7.1e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EPS28473.1 - 1.4e-05 25.3 0.0 0.0054 17.1 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat DUF3342 PF11822.8 EPS28473.1 - 0.0035 17.5 0.1 0.0086 16.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) Ank_3 PF13606.6 EPS28473.1 - 0.033 14.7 0.1 0.33 11.7 0.1 2.7 2 0 0 2 2 2 0 Ankyrin repeat Auxin_inducible PF02519.14 EPS28473.1 - 0.2 11.8 0.4 3.4 7.9 0.2 2.5 2 0 0 2 2 2 0 Auxin responsive protein MazG-like PF12643.7 EPS28474.1 - 0.011 16.0 0.2 0.014 15.7 0.2 1.1 1 0 0 1 1 1 0 MazG-like family DUF4446 PF14584.6 EPS28474.1 - 0.026 14.5 1.0 0.03 14.3 1.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) HTH_40 PF14493.6 EPS28474.1 - 0.039 14.4 0.4 0.046 14.2 0.4 1.1 1 0 0 1 1 1 0 Helix-turn-helix domain MMTV_SAg PF01054.17 EPS28474.1 - 0.1 12.1 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 Mouse mammary tumour virus superantigen DUF4224 PF13986.6 EPS28474.1 - 0.23 11.4 1.6 0.52 10.3 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4224) Osmo_CC PF08946.10 EPS28474.1 - 3 8.2 6.1 21 5.5 0.0 3.0 2 1 1 3 3 3 0 Osmosensory transporter coiled coil SMC_N PF02463.19 EPS28475.1 - 8.5e-23 80.9 0.0 5.6e-22 78.3 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EPS28475.1 - 2.9e-17 63.8 0.3 2.9e-17 63.8 0.3 4.7 2 2 1 4 4 3 1 AAA domain AAA_29 PF13555.6 EPS28475.1 - 6.2e-05 22.7 0.1 0.0002 21.0 0.0 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EPS28475.1 - 8.3e-05 22.5 1.8 0.035 13.9 0.0 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system APG6_N PF17675.1 EPS28475.1 - 0.005 17.4 1.3 0.005 17.4 1.3 6.9 3 2 3 6 6 4 1 Apg6 coiled-coil region UPF0242 PF06785.11 EPS28475.1 - 0.0072 16.5 5.7 0.0072 16.5 5.7 6.1 2 2 4 6 6 4 1 Uncharacterised protein family (UPF0242) N-terminus HIP1_clath_bdg PF16515.5 EPS28475.1 - 0.012 16.3 1.0 0.012 16.3 1.0 7.5 4 2 3 7 7 6 0 Clathrin-binding domain of Huntingtin-interacting protein 1 AAA_15 PF13175.6 EPS28475.1 - 0.061 13.0 27.7 0.0053 16.5 10.5 4.2 2 2 1 3 3 3 0 AAA ATPase domain UPF0184 PF03670.13 EPS28475.1 - 0.074 13.5 2.1 2.5 8.6 0.4 3.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) AAA_27 PF13514.6 EPS28475.1 - 0.089 12.4 0.0 0.089 12.4 0.0 4.7 4 1 0 4 4 4 0 AAA domain AAA_25 PF13481.6 EPS28475.1 - 0.19 11.3 1.5 0.5 9.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain TcpS PF17456.2 EPS28475.1 - 0.32 11.1 0.0 0.32 11.1 0.0 3.3 4 0 0 4 4 4 0 Toxin-coregulated pilus protein S Synaptonemal_3 PF15191.6 EPS28475.1 - 0.33 10.8 2.7 8.3 6.3 0.1 3.3 2 0 0 2 2 2 0 Synaptonemal complex central element protein 3 HAD_SAK_1 PF10307.9 EPS28475.1 - 2.4 7.9 13.7 1.5 8.6 0.0 3.7 3 1 1 4 4 4 0 HAD domain family 1 in Swiss Army Knife RNA repair proteins Spc7 PF08317.11 EPS28475.1 - 4.2 6.2 78.0 0.014 14.3 1.2 6.1 3 2 1 6 6 6 0 Spc7 kinetochore protein DUF3502 PF12010.8 EPS28475.1 - 5.6 7.6 12.8 4.6 7.9 3.7 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3502) Phlebovirus_NSM PF07246.11 EPS28475.1 - 9.3 5.5 16.6 0.99 8.7 0.4 3.1 2 0 0 2 2 2 0 Phlebovirus nonstructural protein NS-M zf-C2H2 PF00096.26 EPS28479.1 - 6.9e-06 26.2 17.5 0.0044 17.4 4.6 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EPS28479.1 - 0.0029 18.0 3.6 0.0029 18.0 3.6 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EPS28479.1 - 0.033 15.0 16.0 0.64 11.0 3.7 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.7 EPS28479.1 - 0.44 11.0 4.5 1 9.9 2.2 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-BED PF02892.15 EPS28479.1 - 4.2 7.5 9.2 3.6 7.7 3.1 2.5 1 1 1 2 2 2 0 BED zinc finger Lipase_3 PF01764.25 EPS28480.1 - 3.5e-14 52.9 0.2 1.1e-10 41.5 0.0 2.5 2 0 0 2 2 2 2 Lipase (class 3) Abhydrolase_6 PF12697.7 EPS28480.1 - 0.00039 21.1 1.7 0.0012 19.5 1.4 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family FMN_dh PF01070.18 EPS28481.1 - 5.9e-121 403.7 0.0 6.7e-121 403.6 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.14 EPS28481.1 - 7.7e-06 25.4 0.8 0.071 12.4 0.0 2.6 2 1 0 3 3 3 2 Thiazole biosynthesis protein ThiG NMO PF03060.15 EPS28481.1 - 6.1e-05 22.6 1.2 9.3e-05 22.0 1.2 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.17 EPS28481.1 - 0.00046 19.4 0.3 0.00079 18.7 0.3 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 EPS28481.1 - 0.0011 18.1 0.9 0.0023 17.0 0.5 1.7 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 EPS28481.1 - 0.022 14.2 0.3 2.3 7.6 0.1 2.6 1 1 1 2 2 2 0 Histidine biosynthesis protein MFS_1 PF07690.16 EPS28482.1 - 3.4e-34 118.3 29.2 4e-34 118.1 27.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Phage_holin_2_1 PF04971.12 EPS28482.1 - 0.13 12.3 11.2 0.68 10.0 0.1 3.4 3 0 0 3 3 3 0 Bacteriophage P21 holin S His_Phos_2 PF00328.22 EPS28483.1 - 5e-33 115.0 0.0 6.9e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) NAC PF01849.18 EPS28485.1 - 7.1e-23 80.4 0.1 1.4e-22 79.4 0.1 1.5 1 0 0 1 1 1 1 NAC domain T3SSipB PF16535.5 EPS28485.1 - 0.0056 17.2 0.4 0.17 12.4 0.0 2.1 2 0 0 2 2 2 1 Type III cell invasion protein SipB MAGI_u1 PF16663.5 EPS28485.1 - 0.017 15.2 0.0 0.037 14.1 0.0 1.6 1 0 0 1 1 1 0 Unstructured region on MAGI FSH1 PF03959.13 EPS28486.1 - 5.4e-36 124.2 0.0 6.7e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 EPS28486.1 - 1.9e-05 25.3 0.1 3e-05 24.7 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 EPS28486.1 - 0.0056 16.5 0.0 0.0084 15.9 0.0 1.4 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase PE-PPE PF08237.11 EPS28486.1 - 0.042 13.4 0.0 0.063 12.8 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain DUF3089 PF11288.8 EPS28486.1 - 0.045 13.3 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Abhydrolase_1 PF00561.20 EPS28486.1 - 0.045 13.4 0.0 0.064 12.9 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 EPS28486.1 - 0.064 13.4 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Glyco_trans_4_4 PF13579.6 EPS28486.1 - 0.11 12.9 0.0 0.14 12.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 EPS28486.1 - 0.15 12.0 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Abhydrolase_2 PF02230.16 EPS28487.1 - 7.6e-58 195.9 0.0 8.8e-58 195.7 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 EPS28487.1 - 2.1e-06 27.2 0.1 0.00086 18.6 0.0 2.8 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EPS28487.1 - 6.9e-06 25.7 0.1 0.00033 20.2 0.0 2.5 3 0 0 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EPS28487.1 - 1.7e-05 25.5 0.0 0.0075 16.9 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family FSH1 PF03959.13 EPS28487.1 - 0.00031 20.5 0.0 0.0013 18.4 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) BAAT_C PF08840.11 EPS28487.1 - 0.0039 17.1 0.0 0.026 14.4 0.0 2.0 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 EPS28487.1 - 0.029 14.2 0.0 0.086 12.7 0.0 1.7 1 1 0 2 2 2 0 alpha/beta hydrolase fold DLH PF01738.18 EPS28487.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.4 1 1 0 1 1 1 0 Dienelactone hydrolase family DUF2974 PF11187.8 EPS28487.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.20 EPS28487.1 - 0.28 10.8 1.1 5.3 6.6 1.2 2.6 1 1 1 2 2 2 0 alpha/beta hydrolase fold MARVEL PF01284.23 EPS28488.1 - 9.9e-05 22.4 13.2 0.00017 21.6 13.2 1.3 1 1 0 1 1 1 1 Membrane-associating domain DUF3611 PF12263.8 EPS28488.1 - 0.051 13.5 3.4 0.13 12.2 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3611) AATase PF07247.12 EPS28490.1 - 1.3e-15 56.9 0.0 7.9e-14 51.1 0.0 2.9 1 1 0 1 1 1 1 Alcohol acetyltransferase WES_acyltransf PF03007.16 EPS28490.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.5 1 1 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Condensation PF00668.20 EPS28490.1 - 0.26 9.9 0.0 5.3 5.6 0.0 2.1 2 0 0 2 2 2 0 Condensation domain MGC-24 PF05283.11 EPS28491.1 - 0.05 14.0 3.8 0.07 13.6 3.8 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin RAP1 PF07218.11 EPS28491.1 - 6 5.0 6.1 7.8 4.6 6.1 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ctr PF04145.15 EPS28492.1 - 6.5e-31 108.0 0.2 8.1e-31 107.6 0.2 1.1 1 0 0 1 1 1 1 Ctr copper transporter family PAP2 PF01569.21 EPS28492.1 - 4.3 7.1 12.9 58 3.5 12.9 2.1 1 1 0 1 1 1 0 PAP2 superfamily FAD_binding_8 PF08022.12 EPS28493.1 - 7.1e-21 74.3 0.0 1.9e-20 72.9 0.0 1.8 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.19 EPS28493.1 - 1.4e-20 73.6 10.4 2.7e-20 72.7 10.4 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EPS28493.1 - 6e-16 58.9 0.0 1.8e-15 57.4 0.0 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 EPS28493.1 - 0.066 13.9 0.0 22 5.7 0.0 2.5 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF3247 PF11607.8 EPS28493.1 - 0.13 12.6 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3247) DUF1687 PF07955.11 EPS28494.1 - 3.2e-25 89.1 0.0 3.9e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) Pkinase PF00069.25 EPS28495.1 - 6.7e-60 202.7 0.0 5.6e-59 199.6 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS28495.1 - 2.1e-28 99.3 0.2 5.9e-20 71.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EPS28495.1 - 5.8e-05 23.1 1.4 0.095 12.6 0.1 3.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 EPS28495.1 - 0.0011 18.3 0.6 0.005 16.2 0.0 2.2 3 0 0 3 3 3 1 Kinase-like Pkinase_C PF00433.24 EPS28495.1 - 0.0041 17.8 0.7 0.0041 17.8 0.7 2.1 2 1 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EPS28495.1 - 0.0092 15.0 0.0 0.017 14.1 0.0 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EPS28495.1 - 0.021 14.2 0.2 0.13 11.6 0.0 2.1 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Fungal_trans PF04082.18 EPS28496.1 - 2.5e-19 69.3 2.8 4.8e-19 68.4 2.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain TSC22 PF01166.18 EPS28496.1 - 0.16 12.3 0.2 0.37 11.1 0.2 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family Epimerase PF01370.21 EPS28497.1 - 3.9e-25 88.7 0.8 2.4e-24 86.1 0.8 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EPS28497.1 - 1.4e-15 57.5 0.0 3.4e-15 56.3 0.0 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EPS28497.1 - 4.8e-08 32.4 0.1 1.5e-07 30.7 0.1 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EPS28497.1 - 4.8e-08 32.4 0.0 1.3e-07 31.1 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EPS28497.1 - 1.9e-07 30.5 0.1 8.9e-06 25.1 0.0 2.1 1 1 0 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.6 EPS28497.1 - 3.7e-06 26.9 0.0 6.1e-06 26.2 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EPS28497.1 - 0.00039 19.6 0.0 0.0024 17.1 0.0 2.1 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 EPS28497.1 - 0.023 14.3 0.0 0.033 13.8 0.0 1.4 1 1 0 1 1 1 0 NmrA-like family KR PF08659.10 EPS28497.1 - 0.19 11.7 0.1 1.4 8.8 0.1 2.1 1 1 0 1 1 1 0 KR domain ILVD_EDD PF00920.21 EPS28498.1 - 2.7e-160 534.4 0.0 3.1e-160 534.2 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family Fungal_trans_2 PF11951.8 EPS28500.1 - 3.9e-10 39.1 0.1 4.9e-10 38.8 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain APH PF01636.23 EPS28503.1 - 2e-11 44.3 0.0 0.00012 22.1 0.1 2.2 1 1 0 2 2 2 2 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EPS28503.1 - 0.056 12.7 0.0 0.096 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Fructosamin_kin PF03881.14 EPS28503.1 - 0.097 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase TrkH PF02386.16 EPS28504.1 - 6.1e-127 424.1 3.2 3.7e-125 418.2 0.7 2.1 2 0 0 2 2 2 2 Cation transport protein ICL PF00463.21 EPS28505.1 - 1.1e-191 637.9 0.0 1.3e-191 637.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 EPS28505.1 - 6.8e-09 35.5 0.1 1.8e-08 34.2 0.0 1.6 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF2458 PF10454.9 EPS28505.1 - 0.11 12.2 0.4 0.28 10.8 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) Glyco_hydro_72 PF03198.14 EPS28506.1 - 8.5e-126 419.5 7.5 1.2e-125 419.0 7.5 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 EPS28506.1 - 1.5e-25 89.6 7.0 5e-25 88.0 7.0 2.0 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.18 EPS28506.1 - 3.4e-06 26.7 0.5 5.6e-06 26.0 0.5 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.17 EPS28506.1 - 0.12 11.4 2.5 0.54 9.3 2.5 2.1 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain MFS_1 PF07690.16 EPS28507.1 - 8.1e-38 130.2 48.1 9.2e-37 126.8 45.6 3.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EPS28507.1 - 9.5e-15 54.0 14.9 1.4e-14 53.4 14.9 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EPS28507.1 - 0.0039 15.6 2.5 0.0039 15.6 2.5 3.3 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family DUF3422 PF11902.8 EPS28507.1 - 0.14 11.3 0.4 0.2 10.7 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3422) E1-E2_ATPase PF00122.20 EPS28507.1 - 0.22 11.0 3.1 0.38 10.3 1.4 2.2 2 0 0 2 2 2 0 E1-E2 ATPase UPF0139 PF03669.13 EPS28507.1 - 3.4 7.6 6.9 17 5.3 0.0 3.8 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0139) FSH1 PF03959.13 EPS28508.1 - 8.3e-28 97.5 0.0 2.7e-27 95.8 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) ketoacyl-synt PF00109.26 EPS28509.1 - 6.9e-73 245.3 0.0 1.6e-72 244.1 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EPS28509.1 - 1.5e-50 172.5 0.6 2.6e-50 171.7 0.6 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 EPS28509.1 - 7.1e-45 153.5 0.0 1.3e-44 152.7 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 EPS28509.1 - 2.9e-44 151.1 0.6 6.3e-44 150.0 0.1 1.9 2 0 0 2 2 2 1 KR domain Ketoacyl-synt_C PF02801.22 EPS28509.1 - 3.5e-36 123.8 1.8 1e-35 122.3 0.0 2.7 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 EPS28509.1 - 3.8e-20 72.5 0.0 1.2e-19 70.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EPS28509.1 - 6.2e-17 62.1 0.0 1.6e-16 60.7 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 EPS28509.1 - 1.8e-16 60.2 6.0 2e-16 60.0 0.8 3.3 3 0 0 3 3 3 1 short chain dehydrogenase ADH_zinc_N PF00107.26 EPS28509.1 - 1.1e-15 57.8 0.3 1.5e-14 54.1 0.0 3.0 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 EPS28509.1 - 2.3e-13 50.3 0.0 5.2e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPS28509.1 - 6.5e-12 46.0 0.0 2.7e-11 44.0 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 EPS28509.1 - 1.1e-11 45.9 0.0 2.4e-09 38.3 0.0 3.8 4 0 0 4 4 3 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.12 EPS28509.1 - 4.8e-10 39.9 0.0 1.5e-09 38.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EPS28509.1 - 1.7e-08 34.7 1.4 4.5e-08 33.3 1.4 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.6 EPS28509.1 - 2.4e-07 30.6 0.0 7.4e-07 29.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain adh_short_C2 PF13561.6 EPS28509.1 - 2.4e-06 27.3 0.2 7e-06 25.8 0.2 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Thiolase_N PF00108.23 EPS28509.1 - 2.2e-05 24.0 0.2 0.00011 21.6 0.1 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain SAT PF16073.5 EPS28509.1 - 4.7e-05 23.2 2.0 0.00013 21.8 2.0 1.8 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Ubie_methyltran PF01209.18 EPS28509.1 - 6.7e-05 22.3 0.0 0.00016 21.1 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family ADH_N PF08240.12 EPS28509.1 - 0.0001 22.1 0.7 0.00033 20.5 0.7 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III PF08545.10 EPS28509.1 - 1.8 8.5 5.7 1.1 9.2 0.6 3.1 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF3237 PF11578.8 EPS28510.1 - 5.1e-35 120.5 0.0 7.6e-35 119.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) zf-BED PF02892.15 EPS28510.1 - 0.00013 21.9 3.9 0.08 13.0 0.3 2.4 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_2 PF12756.7 EPS28510.1 - 0.053 13.9 4.9 3.2 8.1 0.3 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Zn_Tnp_IS91 PF14319.6 EPS28510.1 - 0.64 10.1 11.5 0.79 9.8 2.2 2.2 2 0 0 2 2 2 0 Transposase zinc-binding domain PyrI_C PF02748.15 EPS28510.1 - 1.1 9.3 6.0 7.3 6.6 0.5 2.3 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Rad21_Rec8_N PF04825.13 EPS28511.1 - 1.8e-29 102.1 0.0 3.5e-29 101.2 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EPS28511.1 - 5.3e-07 28.8 0.0 1.3e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein NAT PF04768.13 EPS28512.1 - 2.8e-53 180.0 0.1 6.1e-53 179.0 0.0 1.6 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 EPS28512.1 - 5e-31 107.7 0.0 1.5e-30 106.1 0.0 1.9 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 EPS28512.1 - 1.9e-28 99.7 0.0 4.3e-28 98.5 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.20 EPS28512.1 - 0.071 13.2 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Synaptobrevin PF00957.21 EPS28513.1 - 1.2e-33 114.7 0.8 1.4e-33 114.5 0.8 1.0 1 0 0 1 1 1 1 Synaptobrevin AKNA PF12443.8 EPS28513.1 - 0.035 14.8 0.1 0.082 13.6 0.1 1.6 1 1 1 2 2 2 0 AT-hook-containing transcription factor Prominin PF05478.11 EPS28513.1 - 0.051 11.5 0.2 0.062 11.2 0.2 1.1 1 0 0 1 1 1 0 Prominin PRT_C PF08372.10 EPS28513.1 - 0.051 13.3 0.6 0.066 13.0 0.6 1.2 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal Fzo_mitofusin PF04799.13 EPS28513.1 - 0.066 12.8 0.5 0.083 12.4 0.3 1.2 1 1 0 1 1 1 0 fzo-like conserved region Orf78 PF06024.12 EPS28513.1 - 0.15 12.4 0.7 0.22 11.8 0.7 1.5 1 1 0 1 1 1 0 Orf78 (ac78) Sel1 PF08238.12 EPS28516.1 - 4e-42 141.7 33.4 1.8e-07 31.6 0.2 7.8 8 0 0 8 8 8 7 Sel1 repeat LigB PF02900.18 EPS28517.1 - 7.9e-35 120.2 0.0 1e-34 119.9 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase PGA_cap PF09587.10 EPS28517.1 - 0.1 12.1 0.0 0.52 9.7 0.0 2.0 1 1 1 2 2 2 0 Bacterial capsule synthesis protein PGA_cap L51_S25_CI-B8 PF05047.16 EPS28518.1 - 4.7e-13 48.8 0.0 6.2e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MPC PF03650.13 EPS28519.1 - 3.7e-50 168.7 0.8 5e-50 168.3 0.8 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers DUF2863 PF11062.8 EPS28519.1 - 0.0061 15.0 0.7 0.024 13.0 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2863) Glyco_hydro_28 PF00295.17 EPS28520.1 - 9.8e-53 179.3 12.1 1.6e-52 178.6 12.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Zn_clus PF00172.18 EPS28521.1 - 8.3e-08 32.2 5.8 8.3e-08 32.2 5.8 2.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 EPS28521.1 - 7.5e-06 26.1 15.1 0.0046 17.3 5.5 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type Fungal_trans PF04082.18 EPS28521.1 - 3.3e-05 23.1 1.3 4.3e-05 22.7 1.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.6 EPS28521.1 - 0.012 16.4 3.7 0.012 16.4 3.7 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger BolA PF01722.18 EPS28521.1 - 0.1 12.9 0.1 0.2 12.0 0.1 1.5 1 0 0 1 1 1 0 BolA-like protein zf-H2C2_2 PF13465.6 EPS28521.1 - 0.13 12.7 12.3 0.051 14.0 3.9 3.4 3 0 0 3 3 3 0 Zinc-finger double domain zf-met PF12874.7 EPS28521.1 - 0.55 10.7 0.1 0.55 10.7 0.1 2.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type NAD_binding_8 PF13450.6 EPS28522.1 - 8.6e-13 48.3 0.0 2.6e-12 46.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EPS28522.1 - 1.4e-09 37.6 0.0 7.8e-08 31.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EPS28522.1 - 2.7e-08 32.7 5.5 8.5e-08 31.1 1.7 3.2 3 1 0 3 3 3 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EPS28522.1 - 8.8e-07 28.4 0.2 0.0027 16.9 0.1 3.0 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EPS28522.1 - 1.1e-06 28.7 1.5 0.00017 21.6 0.0 3.9 4 1 0 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.24 EPS28522.1 - 1.2e-05 25.1 0.0 0.0086 15.7 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EPS28522.1 - 6.8e-05 22.3 0.7 0.32 10.2 0.1 3.8 2 2 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EPS28522.1 - 0.00034 19.9 0.1 0.0011 18.3 0.0 1.8 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 EPS28522.1 - 0.099 11.7 0.4 13 4.8 0.0 2.5 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 EPS28522.1 - 0.18 10.5 0.1 0.42 9.3 0.1 1.6 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 EPS28523.1 - 3.6e-75 253.4 0.0 6.8e-74 249.2 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EPS28523.1 - 1.5e-29 103.1 0.0 2.9e-29 102.3 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 EPS28523.1 - 0.0057 15.9 0.3 0.023 13.9 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EPS28523.1 - 0.046 12.8 0.0 0.11 11.5 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase HI0933_like PF03486.14 EPS28523.1 - 0.15 10.7 0.0 0.23 10.1 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Lactamase_B_2 PF12706.7 EPS28525.1 - 1.5e-16 60.5 0.0 2.1e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EPS28525.1 - 2.7e-12 46.9 0.0 3.8e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain BAALC_N PF06989.12 EPS28525.1 - 0.02 15.2 0.0 0.053 13.8 0.0 1.6 1 0 0 1 1 1 0 BAALC N-terminus Amnionless PF14828.6 EPS28526.1 - 0.0087 14.9 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 Amnionless EphA2_TM PF14575.6 EPS28526.1 - 0.017 16.0 0.0 0.061 14.2 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain VSP PF03302.13 EPS28526.1 - 0.38 9.6 5.1 0.23 10.3 3.0 1.6 2 0 0 2 2 2 0 Giardia variant-specific surface protein DDE_1 PF03184.19 EPS28527.1 - 3.8e-38 130.9 0.1 6.4e-37 126.9 0.0 2.3 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_ABP1_N PF18107.1 EPS28527.1 - 7e-25 86.5 1.7 2.8e-24 84.6 0.2 2.6 2 0 0 2 2 2 1 Fission yeast centromere protein N-terminal domain HTH_Tnp_Tc5 PF03221.16 EPS28527.1 - 1.3e-15 57.2 9.0 4.6e-14 52.2 0.4 3.3 3 0 0 3 3 3 2 Tc5 transposase DNA-binding domain Dioxygenase_C PF00775.21 EPS28528.1 - 6.7e-09 35.4 0.2 3.2e-08 33.2 0.0 2.0 2 1 0 2 2 2 1 Dioxygenase Sugar_tr PF00083.24 EPS28529.1 - 2.1e-125 419.1 28.3 2.4e-125 418.9 28.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS28529.1 - 5e-27 94.7 56.1 4.9e-24 84.9 29.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EPS28529.1 - 0.0042 15.6 0.7 0.0042 15.6 0.7 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PEMT PF04191.13 EPS28533.1 - 1.2e-11 44.9 1.2 1.2e-11 44.9 1.2 2.5 2 1 1 3 3 3 1 Phospholipid methyltransferase ICMT PF04140.14 EPS28533.1 - 1.1e-10 41.8 2.3 1.4e-09 38.3 0.7 2.7 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1295 PF06966.12 EPS28533.1 - 0.015 14.8 0.2 0.021 14.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) DUF4175 PF13779.6 EPS28533.1 - 0.085 10.8 0.0 0.12 10.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) AA_permease_2 PF13520.6 EPS28534.1 - 1.2e-53 182.5 58.0 1.5e-53 182.2 58.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPS28534.1 - 8.5e-11 41.1 52.4 1.9e-10 39.9 52.4 1.4 1 1 0 1 1 1 1 Amino acid permease Amino_oxidase PF01593.24 EPS28535.1 - 6.6e-61 207.0 0.3 6.4e-60 203.7 0.3 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EPS28535.1 - 5.6e-08 32.9 0.0 1.3e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EPS28535.1 - 0.0044 16.3 0.0 0.033 13.4 0.1 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EPS28535.1 - 0.0088 15.3 0.5 0.038 13.2 0.5 2.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPS28535.1 - 0.038 14.5 0.3 0.19 12.3 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EPS28535.1 - 0.049 13.0 0.1 0.085 12.2 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 EPS28535.1 - 0.062 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.17 EPS28535.1 - 0.091 12.0 0.1 0.17 11.1 0.1 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 EPS28535.1 - 0.13 11.3 0.3 0.2 10.7 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 EPS28535.1 - 0.13 11.4 0.0 0.65 9.2 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 EPS28535.1 - 0.73 9.4 3.3 0.67 9.5 0.2 2.4 3 1 0 3 3 3 0 FAD dependent oxidoreductase Malate_synthase PF01274.22 EPS28537.1 - 2.1e-232 772.0 0.0 2.4e-232 771.9 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Glyco_hydro_3_C PF01915.22 EPS28539.1 - 5.4e-47 160.4 0.0 9.4e-47 159.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EPS28539.1 - 7.9e-38 130.6 0.0 1.3e-37 129.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EPS28539.1 - 6.4e-23 80.7 0.1 1.5e-22 79.5 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain ABC_tran PF00005.27 EPS28540.1 - 7.4e-47 159.3 0.0 3.7e-25 89.0 0.0 4.1 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EPS28540.1 - 1.7e-15 57.7 0.2 0.00022 21.2 0.0 4.3 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EPS28540.1 - 2.4e-11 43.5 1.6 0.0066 15.9 0.0 4.5 4 1 0 4 4 3 2 RecF/RecN/SMC N terminal domain Chromo PF00385.24 EPS28540.1 - 2.2e-07 30.7 0.0 4.1e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.6 EPS28540.1 - 3.6e-07 30.9 1.2 0.013 16.0 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 EPS28540.1 - 2.2e-06 27.3 1.5 0.025 14.3 0.6 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EPS28540.1 - 4.8e-06 26.6 0.4 0.11 12.5 0.0 3.2 3 0 0 3 3 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EPS28540.1 - 2.7e-05 24.2 0.1 0.16 11.9 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 EPS28540.1 - 6.9e-05 22.7 0.5 0.097 12.4 0.8 2.3 2 0 0 2 2 2 2 AAA ATPase domain DUF87 PF01935.17 EPS28540.1 - 0.00068 19.8 0.5 0.26 11.4 0.2 3.1 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_28 PF13521.6 EPS28540.1 - 0.0012 19.1 0.0 1.2 9.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EPS28540.1 - 0.0021 18.3 0.0 0.63 10.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EPS28540.1 - 0.0023 18.3 0.0 1.4 9.4 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_13 PF13166.6 EPS28540.1 - 0.0027 16.4 0.0 0.17 10.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.6 EPS28540.1 - 0.0076 16.5 0.1 3.9 7.8 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 EPS28540.1 - 0.0092 15.9 0.2 0.66 9.9 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 EPS28540.1 - 0.012 15.3 0.4 7.9 6.1 0.1 3.3 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 EPS28540.1 - 0.017 15.2 0.1 2.6 8.1 0.0 3.0 2 1 0 2 2 2 0 Dynamin family AAA_33 PF13671.6 EPS28540.1 - 0.017 15.3 0.0 1.9 8.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EPS28540.1 - 0.033 13.9 0.2 3.8 7.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 EPS28540.1 - 0.039 12.9 0.2 4.3 6.2 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MukB PF04310.12 EPS28540.1 - 0.042 13.6 0.2 4.9 6.9 0.0 2.4 2 0 0 2 2 2 0 MukB N-terminal AAA_27 PF13514.6 EPS28540.1 - 0.056 13.0 0.1 7.5 6.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EPS28540.1 - 0.13 12.7 0.0 4.2 7.8 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EPS28540.1 - 0.13 12.8 0.0 26 5.4 0.0 3.1 3 0 0 3 3 2 0 AAA domain DUF815 PF05673.13 EPS28540.1 - 0.14 11.3 0.3 8.4 5.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Septin PF00735.18 EPS28540.1 - 0.17 11.2 0.0 18 4.5 0.0 2.3 2 0 0 2 2 2 0 Septin HEAT_EZ PF13513.6 EPS28540.1 - 0.17 12.4 0.3 5.5 7.6 0.0 3.4 3 0 0 3 3 2 0 HEAT-like repeat CLP1_P PF16575.5 EPS28540.1 - 0.17 11.6 0.8 14 5.4 0.0 3.0 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop ALF PF03752.13 EPS28540.1 - 1.9 8.5 7.2 6.8 6.7 0.2 3.4 3 1 0 3 3 3 0 Short repeats of unknown function HEAT_2 PF13646.6 EPS28540.1 - 2.1 8.8 6.6 6.5 7.2 0.0 4.3 3 2 2 5 5 5 0 HEAT repeats Citrate_synt PF00285.21 EPS28541.1 - 2.1e-96 323.1 0.0 2.6e-96 322.9 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain AMP-binding PF00501.28 EPS28542.1 - 6.2e-75 252.4 0.0 7.6e-75 252.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EPS28542.1 - 4.1e-06 27.7 0.0 1.2e-05 26.2 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain BP28CT PF08146.12 EPS28543.1 - 0.17 11.7 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 BP28CT (NUC211) domain BATS PF06968.13 EPS28544.1 - 1.6e-22 79.4 0.2 6.2e-22 77.5 0.0 2.0 2 1 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 EPS28544.1 - 4.5e-18 66.2 0.1 2e-16 60.8 0.1 2.5 3 0 0 3 3 3 1 Radical SAM superfamily IGPS PF00218.21 EPS28544.1 - 0.13 11.4 0.0 0.24 10.5 0.0 1.3 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase FA_hydroxylase PF04116.13 EPS28545.1 - 8.1e-24 84.5 16.5 8.1e-24 84.5 16.5 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Tautomerase_3 PF14832.6 EPS28546.1 - 5e-53 179.0 0.0 5.7e-53 178.8 0.0 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Tautomerase PF01361.21 EPS28546.1 - 0.023 14.6 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 Tautomerase enzyme DUF3433 PF11915.8 EPS28547.1 - 4.5e-19 68.7 21.6 2.4e-11 44.0 4.4 4.1 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) MFS_1 PF07690.16 EPS28548.1 - 5.3e-18 65.1 47.3 1.7e-09 37.1 19.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Aminotran_3 PF00202.21 EPS28549.1 - 2.7e-37 128.4 0.0 3.9e-19 68.6 0.0 3.1 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.6 EPS28549.1 - 9.4e-24 84.3 0.0 1.5e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain Aminotran_1_2 PF00155.21 EPS28550.1 - 5e-37 127.9 0.0 5.8e-37 127.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EPS28550.1 - 0.019 13.9 0.0 0.23 10.4 0.0 2.1 2 0 0 2 2 2 0 Aminotransferase class-V OKR_DC_1 PF01276.20 EPS28550.1 - 0.024 13.4 0.0 0.048 12.4 0.0 1.4 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Cys_Met_Meta_PP PF01053.20 EPS28550.1 - 0.043 12.3 0.0 0.057 11.9 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.21 EPS28550.1 - 0.23 10.1 0.0 0.28 9.8 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-III E1-E2_ATPase PF00122.20 EPS28551.1 - 1.8e-34 118.9 4.2 9e-29 100.3 0.0 3.8 3 1 1 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EPS28551.1 - 9.2e-25 87.4 7.9 9.2e-25 87.4 7.9 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.26 EPS28551.1 - 3.1e-19 68.4 0.1 3.1e-19 68.4 0.1 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 EPS28551.1 - 4.5e-18 66.3 0.0 1.6e-16 61.2 0.0 3.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EPS28551.1 - 1e-15 57.5 0.0 2e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EPS28551.1 - 0.00016 21.5 0.1 0.011 15.5 0.3 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DctM PF06808.12 EPS28551.1 - 0.0091 14.9 0.5 0.0091 14.9 0.5 2.8 3 0 0 3 3 3 1 Tripartite ATP-independent periplasmic transporter, DctM component DUF2463 PF09591.10 EPS28551.1 - 0.046 13.6 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2463) NVEALA PF14055.6 EPS28551.1 - 5.4 7.1 6.8 16 5.6 0.0 4.0 3 1 0 3 3 3 0 NVEALA protein zf-RING_2 PF13639.6 EPS28552.1 - 4.3e-08 33.4 5.5 5e-06 26.8 1.9 2.4 2 0 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.7 EPS28552.1 - 8.3e-08 32.4 1.0 8.3e-08 32.4 1.0 2.3 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EPS28552.1 - 1.4e-06 28.1 1.4 2.2e-05 24.2 0.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EPS28552.1 - 2.2e-06 27.4 3.7 4.1e-05 23.3 1.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EPS28552.1 - 1.6e-05 24.9 0.6 3.7e-05 23.7 0.2 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 EPS28552.1 - 1.8e-05 24.4 2.9 0.017 14.8 0.2 3.3 3 0 0 3 3 3 1 RING-like zinc finger Prok-RING_4 PF14447.6 EPS28552.1 - 8.6e-05 22.3 2.5 0.0013 18.5 0.3 2.3 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EPS28552.1 - 0.00048 19.9 3.2 0.0096 15.8 1.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EPS28552.1 - 0.00056 19.5 1.5 0.0012 18.4 1.5 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 EPS28552.1 - 0.00064 19.6 1.3 0.0035 17.3 0.3 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EPS28552.1 - 0.0021 18.1 10.2 0.026 14.5 1.2 3.2 2 1 1 3 3 3 2 RING-type zinc-finger Melittin PF01372.17 EPS28552.1 - 0.035 14.1 0.3 0.18 11.8 0.1 2.1 2 0 0 2 2 2 0 Melittin PHD PF00628.29 EPS28552.1 - 0.094 12.6 0.7 0.094 12.6 0.7 1.8 2 0 0 2 2 1 0 PHD-finger FANCL_C PF11793.8 EPS28552.1 - 0.098 12.8 6.6 3.1 8.0 6.3 2.7 2 1 0 2 2 2 0 FANCL C-terminal domain RINGv PF12906.7 EPS28552.1 - 0.22 11.7 5.4 0.38 10.9 2.6 2.4 2 1 1 3 3 3 0 RING-variant domain Prok-RING_1 PF14446.6 EPS28552.1 - 0.35 10.8 3.7 7.1 6.6 0.1 3.0 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-Nse PF11789.8 EPS28552.1 - 4.6 7.1 6.6 0.65 9.9 2.2 1.8 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit AA_permease_2 PF13520.6 EPS28554.1 - 1.6e-64 218.3 46.2 2e-64 218.0 46.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPS28554.1 - 5.7e-23 81.3 37.6 7.5e-23 80.9 37.6 1.1 1 0 0 1 1 1 1 Amino acid permease MmgE_PrpD PF03972.14 EPS28555.1 - 5.2e-147 489.9 0.1 6.1e-147 489.7 0.1 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DUF1266 PF06889.11 EPS28555.1 - 0.0022 18.0 0.3 0.076 13.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1266) DNA_methylase PF00145.17 EPS28556.1 - 1.5e-41 142.9 0.0 5.8e-28 98.2 0.0 2.3 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase GATase_6 PF13522.6 EPS28557.1 - 6.5e-14 52.3 0.0 2e-13 50.7 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EPS28557.1 - 2.4e-11 43.6 0.0 6.5e-11 42.2 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 EPS28557.1 - 3.4e-08 33.2 0.0 9.4e-08 31.7 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 EPS28557.1 - 0.00018 20.5 0.0 0.00056 18.9 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferases class-II PRTase_2 PF15609.6 EPS28557.1 - 0.062 12.8 0.0 0.16 11.5 0.0 1.6 1 1 0 1 1 1 0 Phosphoribosyl transferase HhH-GPD PF00730.25 EPS28558.1 - 1.3e-06 28.9 0.0 2.7e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EPS28558.1 - 0.019 14.8 0.0 0.058 13.3 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif FAM60A PF15396.6 EPS28558.1 - 0.44 10.5 17.0 0.86 9.6 0.0 3.0 3 0 0 3 3 3 0 Protein Family FAM60A Aldedh PF00171.22 EPS28559.1 - 2.8e-119 398.7 0.0 3.7e-119 398.3 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ADH_N PF08240.12 EPS28562.1 - 0.018 14.9 0.2 0.02 14.8 0.2 1.1 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Clostridium_P47 PF06597.11 EPS28562.1 - 0.31 9.7 1.4 0.33 9.6 1.4 1.0 1 0 0 1 1 1 0 Clostridium P-47 protein SseC PF04888.12 EPS28562.1 - 1.7 8.2 3.7 0.84 9.2 1.0 1.7 1 1 1 2 2 2 0 Secretion system effector C (SseC) like family Mt_ATP-synt_D PF05873.12 EPS28564.1 - 2.9e-22 79.2 1.1 3.5e-22 78.9 1.1 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Spectrin PF00435.21 EPS28564.1 - 0.19 12.2 3.0 3.8 8.1 0.8 2.2 1 1 0 2 2 2 0 Spectrin repeat NAC PF01849.18 EPS28565.1 - 1.6e-22 79.2 0.0 6.8e-22 77.2 0.0 1.9 2 0 0 2 2 2 1 NAC domain GST_C_4 PF14834.6 EPS28565.1 - 0.075 13.4 0.1 0.16 12.4 0.1 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain CDC45 PF02724.14 EPS28565.1 - 0.2 9.9 4.2 0.26 9.5 4.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Cytomega_UL84 PF06284.11 EPS28565.1 - 0.25 9.7 1.5 0.29 9.5 1.5 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein SelP_N PF04592.14 EPS28565.1 - 0.67 9.3 5.6 0.99 8.8 5.6 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Myc_N PF01056.18 EPS28565.1 - 1.5 8.7 7.7 0.87 9.4 5.9 1.4 1 1 0 1 1 1 0 Myc amino-terminal region Pes-10 PF07149.11 EPS28565.1 - 3.1 6.8 9.9 1.5 7.8 7.9 1.5 2 0 0 2 2 2 0 Pes-10 COPI_C PF06957.11 EPS28565.1 - 9.8 4.8 8.8 14 4.3 8.8 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Ribosomal_L14e PF01929.17 EPS28566.1 - 2.9e-28 98.2 0.1 4.7e-28 97.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 EPS28566.1 - 2.6e-07 30.3 0.3 4.9e-07 29.5 0.3 1.5 1 0 0 1 1 1 1 KOW motif YIF1 PF03878.15 EPS28567.1 - 1.6e-100 335.6 4.5 1.9e-100 335.3 4.5 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 EPS28567.1 - 0.0002 21.1 5.5 0.0002 21.1 5.5 1.7 2 0 0 2 2 2 1 Yip1 domain SRP-alpha_N PF04086.13 EPS28568.1 - 9.2e-79 265.4 0.0 1.2e-78 265.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.22 EPS28568.1 - 4.6e-49 166.7 0.0 7.8e-49 166.0 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 EPS28568.1 - 1.3e-09 38.2 0.0 3.1e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 EPS28568.1 - 1.8e-06 27.2 0.0 3.2e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_30 PF13604.6 EPS28568.1 - 0.00058 19.6 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EPS28568.1 - 0.018 15.4 0.0 0.039 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain CbiA PF01656.23 EPS28568.1 - 0.021 14.9 0.0 0.082 13.0 0.0 2.0 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 EPS28568.1 - 0.028 14.1 0.0 0.097 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 EPS28568.1 - 0.037 13.4 0.0 0.064 12.7 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Fer4_NifH PF00142.18 EPS28568.1 - 0.083 12.3 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_31 PF13614.6 EPS28568.1 - 0.1 12.5 0.0 0.64 9.9 0.0 2.0 1 1 1 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EPS28568.1 - 0.12 12.4 0.1 0.47 10.6 0.1 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 EPS28568.1 - 0.12 12.8 0.0 0.27 11.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter MFS_1 PF07690.16 EPS28570.1 - 9.5e-40 136.6 13.4 1.5e-26 93.2 5.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS28570.1 - 5.9e-13 48.5 5.5 2e-09 36.8 0.3 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 EPS28570.1 - 9.7e-07 28.0 1.5 9.7e-07 28.0 1.5 2.6 2 1 1 3 3 3 1 MFS_1 like family MFS_4 PF06779.14 EPS28570.1 - 0.0059 15.9 3.4 0.0059 15.9 3.4 2.8 3 0 0 3 3 3 2 Uncharacterised MFS-type transporter YbfB LacY_symp PF01306.19 EPS28570.1 - 0.011 14.6 2.7 1.9 7.2 0.7 2.5 2 1 0 2 2 2 0 LacY proton/sugar symporter DUF1453 PF07301.11 EPS28570.1 - 0.096 12.7 1.8 0.52 10.3 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1453) DUF2530 PF10745.9 EPS28570.1 - 0.85 9.9 6.5 0.25 11.6 1.2 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2530) Acetyltransf_1 PF00583.25 EPS28572.1 - 1e-10 41.9 0.0 1.4e-10 41.4 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EPS28572.1 - 1.6e-09 37.8 0.0 2.2e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EPS28572.1 - 6.8e-09 36.0 0.0 1e-08 35.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EPS28572.1 - 5e-08 33.1 0.0 2.1e-05 24.6 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EPS28572.1 - 0.003 17.6 0.0 0.0052 16.9 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 EPS28572.1 - 0.017 15.1 0.0 0.036 14.0 0.0 1.5 1 1 0 1 1 1 0 FR47-like protein GNAT_acetyltran PF12746.7 EPS28572.1 - 0.038 13.6 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase AA_permease_2 PF13520.6 EPS28574.1 - 5.7e-50 170.4 45.5 7e-50 170.1 45.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPS28574.1 - 3e-23 82.2 40.3 4.3e-23 81.7 40.3 1.1 1 0 0 1 1 1 1 Amino acid permease Mpv17_PMP22 PF04117.12 EPS28576.1 - 4.3e-16 58.9 2.7 1.1e-15 57.6 0.7 2.2 2 0 0 2 2 2 1 Mpv17 / PMP22 family DUF1270 PF06900.11 EPS28576.1 - 0.13 12.6 2.9 5.6 7.4 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1270) RabGAP-TBC PF00566.18 EPS28577.1 - 1.9e-41 142.1 0.3 4e-41 141.0 0.3 1.6 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 EPS28577.1 - 4.2e-07 29.6 0.0 0.0028 17.2 0.0 3.3 2 1 0 2 2 2 2 Rab-binding domain (RBD) zf-met2 PF12907.7 EPS28578.1 - 1.1e-17 63.8 1.1 1.6e-17 63.4 1.1 1.2 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 EPS28578.1 - 7.1e-07 30.0 10.4 7.1e-07 30.0 10.4 1.5 2 0 0 2 2 2 1 4F5 protein family DUF1005 PF06219.12 EPS28578.1 - 0.06 12.4 0.2 0.068 12.2 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1005) GAS2 PF02187.17 EPS28579.1 - 2.8e-06 27.3 0.0 6e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Hexokinase_2 PF03727.16 EPS28580.1 - 2e-71 240.2 0.0 2.6e-71 239.8 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EPS28580.1 - 2.8e-68 229.7 0.0 5.1e-68 228.9 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Tetrabrachion PF11401.8 EPS28580.1 - 0.084 12.9 1.3 1.5 8.9 0.0 2.9 3 0 0 3 3 3 0 Tetrabrachion Hus1 PF04005.12 EPS28581.1 - 8.8e-96 320.4 0.0 1e-95 320.2 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Sec16_C PF12931.7 EPS28582.1 - 4.5e-112 374.6 0.2 6.3e-112 374.1 0.2 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16_N PF12935.7 EPS28582.1 - 8.8e-45 153.7 24.9 8.8e-45 153.7 24.9 4.2 4 0 0 4 4 4 2 Vesicle coat trafficking protein Sec16 N-terminus Sec16 PF12932.7 EPS28582.1 - 2.2e-35 121.8 0.0 5.5e-35 120.5 0.0 1.7 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region DUF3499 PF12005.8 EPS28582.1 - 4.9 7.8 6.6 4.2 8.0 1.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3499) PhoLip_ATPase_C PF16212.5 EPS28583.1 - 4.7e-46 157.6 9.5 4.7e-46 157.6 9.5 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EPS28583.1 - 6.6e-17 61.0 0.8 1.4e-16 59.9 0.8 1.5 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EPS28583.1 - 3.7e-13 50.3 2.0 1.1e-07 32.4 0.6 3.1 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EPS28583.1 - 4.1e-08 33.2 0.1 1e-05 25.5 0.0 3.4 3 1 0 3 3 3 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EPS28583.1 - 1.4e-06 28.0 0.7 0.0048 16.4 0.1 2.9 2 0 0 2 2 2 2 E1-E2 ATPase Hydrolase_3 PF08282.12 EPS28583.1 - 0.0022 17.8 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Sugar_tr PF00083.24 EPS28584.1 - 5.4e-87 292.5 16.9 7e-87 292.2 16.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS28584.1 - 8e-27 94.1 26.3 1.8e-26 92.9 25.0 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EPS28584.1 - 5.4e-06 25.1 2.8 3e-05 22.7 1.0 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF4131 PF13567.6 EPS28584.1 - 1.5 8.4 6.1 1.4 8.5 0.4 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) DUF1772 PF08592.11 EPS28584.1 - 2.3 8.5 0.0 2.3 8.5 0.0 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF1772) Mso1_Sec1_bdg PF14475.6 EPS28587.1 - 1.4e-13 50.2 0.0 2.8e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Ribosomal_L28e PF01778.17 EPS28588.1 - 9e-39 132.8 1.3 1.6e-38 132.0 1.3 1.4 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.14 EPS28588.1 - 1.2e-31 109.2 10.4 1.2e-31 109.2 10.4 2.4 2 0 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 EPS28588.1 - 1.2e-06 28.2 13.2 1.5e-06 27.9 13.2 1.1 1 0 0 1 1 1 1 BUD22 PYC_OADA PF02436.18 EPS28588.1 - 0.04 13.7 0.3 0.078 12.7 0.2 1.5 1 1 0 1 1 1 0 Conserved carboxylase domain CxC6 PF18721.1 EPS28588.1 - 0.042 14.1 0.7 0.21 11.9 0.4 2.0 2 0 0 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases TFIIF_alpha PF05793.12 EPS28588.1 - 0.11 11.1 22.7 0.12 10.9 22.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Stm1_N PF09598.10 EPS28588.1 - 1.6 9.6 9.8 4.4 8.2 9.8 1.8 1 0 0 1 1 1 0 Stm1 Nop14 PF04147.12 EPS28588.1 - 2.8 6.0 23.3 3.5 5.7 23.3 1.1 1 0 0 1 1 1 0 Nop14-like family DUF3402 PF11882.8 EPS28589.1 - 1.5e-191 637.5 0.0 2.2e-191 637.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.13 EPS28589.1 - 2.6e-89 299.3 0.0 3.9e-89 298.7 0.0 1.3 1 0 0 1 1 1 1 N1221-like protein BP28CT PF08146.12 EPS28589.1 - 0.074 12.9 0.1 0.45 10.4 0.0 2.1 2 0 0 2 2 2 0 BP28CT (NUC211) domain TbpB_C PF17483.2 EPS28589.1 - 0.15 12.4 0.1 0.32 11.4 0.1 1.4 1 0 0 1 1 1 0 C-lobe handle domain of Tf-binding protein B PAP2 PF01569.21 EPS28590.1 - 6.8e-14 51.8 6.1 6.8e-14 51.8 6.1 2.3 1 1 1 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 EPS28590.1 - 0.00039 20.5 0.0 0.004 17.3 0.0 2.2 1 1 0 1 1 1 1 Divergent PAP2 family HRG PF16954.5 EPS28590.1 - 6.6 7.2 9.5 0.094 13.1 1.6 2.1 3 0 0 3 3 3 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene IBR PF01485.21 EPS28592.1 - 7.4e-20 70.9 37.0 4.4e-16 58.8 2.2 4.2 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain RWD PF05773.22 EPS28592.1 - 2.2e-17 63.4 0.0 3.5e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 RWD domain zf-RING_11 PF17123.5 EPS28592.1 - 0.0037 17.0 6.3 0.0037 17.0 6.3 2.4 3 0 0 3 3 3 1 RING-like zinc finger zf-RING_2 PF13639.6 EPS28592.1 - 0.01 16.1 10.5 0.01 16.1 10.5 3.9 3 1 0 3 3 3 0 Ring finger domain Peptidase_S15 PF02129.18 EPS28593.1 - 5.4e-45 154.1 0.0 9.1e-45 153.3 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 EPS28593.1 - 5e-27 95.3 0.0 6.7e-26 91.6 0.0 2.1 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain CRT10 PF08728.10 EPS28594.1 - 1.8e-19 69.4 0.0 4.9e-11 41.6 0.0 2.4 2 0 0 2 2 2 2 CRT10 MMtag PF10159.9 EPS28595.1 - 6.1e-34 116.2 4.7 6.1e-34 116.2 4.7 2.5 2 1 0 2 2 2 1 Multiple myeloma tumor-associated Glyco_hydro_63 PF03200.16 EPS28596.1 - 3.9e-171 570.1 6.5 4e-171 570.1 2.1 2.3 2 1 0 2 2 2 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 EPS28596.1 - 1.4e-81 273.9 0.0 4.1e-81 272.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 EPS28596.1 - 7e-05 21.8 0.5 0.00012 21.1 0.5 1.2 1 0 0 1 1 1 1 Trehalase DAO PF01266.24 EPS28597.1 - 6.1e-72 243.1 0.2 6.9e-72 242.9 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EPS28597.1 - 1.4e-06 28.4 0.1 3.3e-06 27.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EPS28597.1 - 1.6e-06 27.5 0.7 0.0058 15.9 0.1 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EPS28597.1 - 1.1e-05 24.8 0.3 0.1 11.7 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.14 EPS28597.1 - 0.00022 20.2 0.3 0.022 13.7 0.1 2.0 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.27 EPS28597.1 - 0.00074 20.0 0.5 0.04 14.5 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EPS28597.1 - 0.0026 17.8 0.4 0.44 10.5 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Mqo PF06039.15 EPS28597.1 - 0.0064 15.1 0.0 0.15 10.6 0.0 2.0 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) Thi4 PF01946.17 EPS28597.1 - 0.0069 15.6 0.7 0.018 14.3 0.2 1.8 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.22 EPS28597.1 - 0.011 14.9 0.2 1.7 7.7 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 EPS28597.1 - 0.019 14.3 0.7 0.17 11.2 0.7 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EPS28597.1 - 0.02 14.2 0.2 2.1 7.6 0.1 2.5 2 1 0 2 2 2 0 Flavin containing amine oxidoreductase Sacchrp_dh_NADP PF03435.18 EPS28597.1 - 0.03 14.6 0.2 0.13 12.6 0.1 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 EPS28597.1 - 0.067 12.4 0.0 1 8.5 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain GMC_oxred_N PF00732.19 EPS28597.1 - 0.083 12.3 0.1 1.9 7.8 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase MCRA PF06100.11 EPS28597.1 - 0.15 10.8 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 MCRA family SNRNP27 PF08648.12 EPS28598.1 - 3.6e-25 87.8 1.8 7.7e-25 86.7 1.8 1.5 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins Elong_Iki1 PF10483.9 EPS28599.1 - 6.9e-100 334.4 0.0 8e-100 334.2 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 Longin PF13774.6 EPS28600.1 - 1.7e-26 92.1 0.6 2.5e-26 91.5 0.6 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 EPS28600.1 - 1.6e-14 53.5 0.0 3.2e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 Synaptobrevin SLM4 PF16818.5 EPS28600.1 - 0.037 14.0 0.3 0.36 10.8 0.0 2.1 1 1 1 2 2 2 0 Protein SLM4 ASXH PF13919.6 EPS28601.1 - 8.4e-38 129.5 1.4 8.4e-38 129.5 1.4 1.8 2 0 0 2 2 2 1 Asx homology domain AT_hook PF02178.19 EPS28601.1 - 0.03 14.2 3.0 0.091 12.7 3.0 1.8 1 0 0 1 1 1 0 AT hook motif adh_short PF00106.25 EPS28602.1 - 2.5e-26 92.3 0.0 6.9e-26 90.9 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS28602.1 - 2.4e-18 66.5 0.0 6.8e-18 65.1 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPS28602.1 - 0.0005 20.0 0.0 0.00095 19.1 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EPS28602.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) CLPTM1 PF05602.12 EPS28603.1 - 8.1e-163 542.4 0.0 1.1e-162 542.0 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) CENP-I PF07778.11 EPS28604.1 - 7.3e-42 143.8 1.4 2.8e-41 141.8 1.4 1.8 1 1 0 1 1 1 1 Mis6 FANCF PF11107.8 EPS28604.1 - 0.00076 18.8 3.9 0.0014 17.9 2.6 2.0 2 0 0 2 2 2 1 Fanconi anemia group F protein (FANCF) Transcrip_reg PF01709.20 EPS28605.1 - 1.8e-69 233.8 0.1 2.1e-69 233.6 0.1 1.0 1 0 0 1 1 1 1 Transcriptional regulator HEAT_2 PF13646.6 EPS28606.1 - 8.9e-09 35.6 1.0 0.13 12.7 0.0 5.9 4 1 1 5 5 5 4 HEAT repeats Cnd1 PF12717.7 EPS28606.1 - 0.00058 19.9 0.5 6.8 6.7 0.0 5.1 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EPS28606.1 - 0.001 19.1 13.2 20 5.8 0.0 8.7 9 0 0 9 9 9 2 HEAT repeat HEAT_EZ PF13513.6 EPS28606.1 - 0.069 13.7 5.6 13 6.4 0.0 6.1 5 0 0 5 5 5 0 HEAT-like repeat DUF1640 PF07798.11 EPS28607.1 - 1.1e-38 133.1 6.6 1.9e-38 132.3 6.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) LCIB_C_CA PF18599.1 EPS28607.1 - 0.043 13.1 1.3 0.083 12.2 1.3 1.4 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases BUD22 PF09073.10 EPS28607.1 - 0.057 12.8 16.9 0.056 12.8 9.4 2.3 2 0 0 2 2 2 0 BUD22 DUF5305 PF17231.2 EPS28607.1 - 1.9 7.8 5.9 0.18 11.2 0.3 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5305) Tyrosinase PF00264.20 EPS28608.1 - 7.2e-53 180.1 0.6 8.5e-53 179.9 0.6 1.0 1 0 0 1 1 1 1 Common central domain of tyrosinase Vps51 PF08700.11 EPS28609.1 - 1.6e-13 50.5 0.0 7.1e-13 48.4 0.0 2.1 1 0 0 1 1 1 1 Vps51/Vps67 Vps53_N PF04100.12 EPS28609.1 - 0.011 14.8 0.2 0.011 14.8 0.2 1.8 2 0 0 2 2 2 0 Vps53-like, N-terminal Dor1 PF04124.12 EPS28609.1 - 0.028 13.1 1.9 0.28 9.8 0.1 2.4 2 0 0 2 2 2 0 Dor1-like family GlutR_dimer PF00745.20 EPS28609.1 - 0.085 13.3 0.1 4.1 7.9 0.0 3.5 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain Nexin_C PF08628.12 EPS28609.1 - 0.2 12.3 1.3 2.5 8.7 0.1 3.4 4 0 0 4 4 4 0 Sorting nexin C terminal Apolipoprotein PF01442.18 EPS28609.1 - 0.68 9.8 6.4 21 5.0 0.0 3.7 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain D123 PF07065.14 EPS28610.1 - 1.6e-111 372.4 0.1 2.2e-111 371.9 0.1 1.2 1 0 0 1 1 1 1 D123 ECH_1 PF00378.20 EPS28611.1 - 1.1e-26 93.7 0.0 1.4e-26 93.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EPS28611.1 - 7.5e-18 65.1 0.0 8.7e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Pet100 PF09803.9 EPS28612.1 - 3.6e-18 65.8 0.1 4.7e-18 65.5 0.1 1.1 1 0 0 1 1 1 1 Pet100 TMEM247 PF15444.6 EPS28612.1 - 0.077 13.0 1.2 0.091 12.8 1.2 1.1 1 0 0 1 1 1 0 Transmembrane protein 247 SPT_ssu-like PF11779.8 EPS28613.1 - 2.5e-24 84.6 2.8 4.4e-24 83.9 2.8 1.4 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like RF-1 PF00472.20 EPS28614.1 - 9.9e-25 86.7 4.3 1.5e-24 86.2 4.3 1.3 1 0 0 1 1 1 1 RF-1 domain Plasmodium_Vir PF05795.11 EPS28614.1 - 0.51 9.7 6.3 0.64 9.4 6.3 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CAS_CSE1 PF03378.15 EPS28615.1 - 4.8e-188 625.2 0.1 1.1e-187 624.0 0.1 1.6 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 EPS28615.1 - 1e-160 534.6 0.5 1.9e-160 533.7 0.5 1.4 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 EPS28615.1 - 8.9e-17 60.8 1.9 3.1e-16 59.0 0.5 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EPS28615.1 - 0.021 14.9 6.1 0.056 13.5 0.0 4.2 6 0 0 6 6 6 0 Exportin 1-like protein DUF1529 PF07485.11 EPS28615.1 - 0.062 13.2 0.0 0.63 9.9 0.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1259) HhH-GPD PF00730.25 EPS28615.1 - 0.16 12.4 0.0 6 7.4 0.0 2.8 2 0 0 2 2 2 0 HhH-GPD superfamily base excision DNA repair protein DUF3384 PF11864.8 EPS28616.1 - 2.9e-106 356.3 6.1 2.9e-106 356.3 6.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.15 EPS28616.1 - 2e-48 164.4 0.0 3.5e-48 163.6 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.16 EPS28616.1 - 3.9e-36 124.9 1.9 1.1e-32 113.6 0.0 3.4 3 0 0 3 3 3 3 Tuberin PAC3 PF10178.9 EPS28617.1 - 1.4e-05 25.2 0.0 2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 HA2 PF04408.23 EPS28618.1 - 1.4e-26 92.9 0.0 1.4e-26 92.9 0.0 3.3 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EPS28618.1 - 1.6e-12 47.8 0.0 9.4e-12 45.3 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EPS28618.1 - 1.5e-09 37.8 0.0 9.4e-09 35.3 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 EPS28618.1 - 2.5e-08 34.2 0.0 5.6e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_30 PF13604.6 EPS28618.1 - 0.0011 18.8 0.0 0.004 16.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EPS28618.1 - 0.0011 19.3 0.0 0.006 16.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EPS28618.1 - 0.0017 18.7 0.0 0.0042 17.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EPS28618.1 - 0.002 18.2 1.2 2.2 8.2 0.0 3.1 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit DUF2075 PF09848.9 EPS28618.1 - 0.016 14.4 1.2 0.02 14.1 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.6 EPS28618.1 - 0.03 14.8 0.0 0.03 14.8 0.0 4.2 4 0 0 4 4 4 0 AAA domain T2SSE PF00437.20 EPS28618.1 - 0.065 12.3 0.2 0.16 11.0 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_24 PF13479.6 EPS28618.1 - 0.084 12.6 0.0 0.24 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EPS28618.1 - 0.8 9.6 3.7 4.8 7.0 0.0 2.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea cwf21 PF08312.12 EPS28619.1 - 5.8e-17 61.6 17.8 5.8e-17 61.6 17.8 2.4 2 1 0 2 2 2 1 cwf21 domain GvpG PF05120.12 EPS28619.1 - 0.018 15.0 0.7 0.018 15.0 0.7 2.5 3 0 0 3 3 3 0 Gas vesicle protein G CAP_N PF01213.19 EPS28619.1 - 4 6.8 7.7 0.39 10.1 3.5 1.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal PUF PF00806.19 EPS28620.1 - 1.2e-60 197.9 11.0 1.7e-08 33.7 0.2 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat LOB PF03195.14 EPS28620.1 - 0.072 13.7 0.9 3 8.5 0.3 3.5 1 1 2 4 4 4 0 Lateral organ boundaries (LOB) domain CPL PF08144.11 EPS28620.1 - 0.2 12.0 4.4 31 4.9 2.0 4.0 1 1 2 5 5 5 0 CPL (NUC119) domain DUF234 PF03008.14 EPS28620.1 - 0.23 11.9 0.9 0.8 10.2 0.3 2.2 2 0 0 2 2 2 0 Archaea bacterial proteins of unknown function DUF4083 PF13314.6 EPS28623.1 - 0.017 15.1 0.9 0.027 14.4 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) Gram_pos_anchor PF00746.21 EPS28623.1 - 0.44 10.5 3.3 0.91 9.5 3.3 1.5 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Phosphodiest PF01663.22 EPS28624.1 - 5.1e-14 52.6 0.2 7.6e-14 52.1 0.2 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 EPS28624.1 - 2e-05 24.1 0.1 4.6e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 EPS28624.1 - 0.00019 21.0 0.1 0.00036 20.0 0.1 1.5 1 0 0 1 1 1 1 Sulfatase PglZ PF08665.12 EPS28624.1 - 0.012 15.7 0.4 1.9 8.5 0.1 2.2 2 0 0 2 2 2 0 PglZ domain Sugar_tr PF00083.24 EPS28625.1 - 1.8e-86 290.8 16.8 2.1e-86 290.6 16.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS28625.1 - 2.4e-18 66.2 42.6 5.5e-16 58.4 25.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_67M PF07488.12 EPS28626.1 - 2.4e-140 467.2 0.0 3.2e-140 466.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.12 EPS28626.1 - 3.3e-87 291.7 1.1 5.6e-87 291.0 1.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.14 EPS28626.1 - 1e-18 67.8 0.1 2.3e-16 60.2 0.1 2.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus DUF2135 PF09906.9 EPS28626.1 - 0.086 13.2 0.2 0.21 11.9 0.2 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2135) DRAT PF07357.11 EPS28626.1 - 0.16 11.2 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) Glyco_hydro_30C PF17189.4 EPS28627.1 - 1.2e-11 44.7 1.6 3.4e-11 43.2 1.6 1.9 1 0 0 1 1 1 1 Glycosyl hydrolase family 30 beta sandwich domain Glyco_hydr_30_2 PF14587.6 EPS28627.1 - 3.4e-11 43.4 1.3 3.3e-09 36.8 0.0 2.9 2 1 1 3 3 3 1 O-Glycosyl hydrolase family 30 Glyco_hydro_59 PF02057.15 EPS28627.1 - 2.4e-10 40.1 0.0 3.8e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 Glyco_hydro_30 PF02055.16 EPS28627.1 - 1.5e-08 34.1 0.3 1.5e-08 34.1 0.3 2.0 2 1 0 2 2 2 1 Glycosyl hydrolase family 30 TIM-barrel domain Alpha-L-AF_C PF06964.12 EPS28627.1 - 0.0043 17.2 0.4 0.0096 16.1 0.2 1.7 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase C-terminal domain Tyr-DNA_phospho PF06087.12 EPS28628.1 - 2.3e-85 287.1 0.0 3.1e-85 286.7 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 EPS28628.1 - 4.4e-05 23.4 0.0 0.064 13.1 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain UIM PF02809.20 EPS28628.1 - 0.0031 17.3 0.6 0.0075 16.1 0.6 1.7 1 0 0 1 1 1 1 Ubiquitin interaction motif ABC2_membrane PF01061.24 EPS28629.1 - 2.1e-80 269.1 57.0 5.1e-43 146.9 20.2 3.4 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 EPS28629.1 - 1.6e-40 138.8 0.6 2.5e-21 76.6 0.0 3.0 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 EPS28629.1 - 9.8e-28 95.9 10.6 4.4e-25 87.4 0.0 3.2 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 EPS28629.1 - 4.4e-16 59.3 0.5 4.4e-16 59.3 0.5 2.3 2 0 0 2 2 1 1 ABC-transporter N-terminal AAA_18 PF13238.6 EPS28629.1 - 3.4e-06 27.6 0.0 0.0004 20.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EPS28629.1 - 5.3e-06 26.9 0.0 0.0043 17.5 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EPS28629.1 - 1.2e-05 25.3 0.1 0.00066 19.6 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 EPS28629.1 - 1.4e-05 25.1 0.0 0.0078 16.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EPS28629.1 - 0.0001 22.3 0.1 0.11 12.6 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase ABC2_membrane_3 PF12698.7 EPS28629.1 - 0.00024 20.3 13.3 0.00024 20.3 13.3 3.4 3 1 0 3 3 2 1 ABC-2 family transporter protein AAA_29 PF13555.6 EPS28629.1 - 0.00026 20.7 0.2 0.5 10.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_24 PF13479.6 EPS28629.1 - 0.00036 20.3 0.1 0.1 12.3 0.2 3.1 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EPS28629.1 - 0.00036 20.7 0.9 0.012 15.8 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.6 EPS28629.1 - 0.00038 20.7 0.0 0.057 13.7 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 EPS28629.1 - 0.00046 19.8 0.1 0.4 10.2 0.1 2.9 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EPS28629.1 - 0.00076 19.8 0.8 0.0038 17.5 0.1 2.6 3 0 0 3 3 3 1 AAA domain cobW PF02492.19 EPS28629.1 - 0.0017 18.0 0.1 0.011 15.3 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 EPS28629.1 - 0.0036 17.2 0.2 0.19 11.7 0.2 2.5 2 0 0 2 2 2 1 NACHT domain SMC_N PF02463.19 EPS28629.1 - 0.0057 16.1 1.8 0.03 13.8 0.0 2.7 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain TsaE PF02367.17 EPS28629.1 - 0.033 14.2 0.2 0.34 10.9 0.2 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 EPS28629.1 - 0.036 14.5 0.1 9.3 6.7 0.1 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 EPS28629.1 - 0.037 13.2 0.1 2.5 7.2 0.1 2.6 2 0 0 2 2 2 0 NB-ARC domain Septin PF00735.18 EPS28629.1 - 0.078 12.2 0.1 0.42 9.9 0.1 2.1 2 0 0 2 2 2 0 Septin FtsK_SpoIIIE PF01580.18 EPS28629.1 - 0.11 11.8 0.3 6.3 6.1 0.1 2.7 3 0 0 3 3 2 0 FtsK/SpoIIIE family AAA_17 PF13207.6 EPS28629.1 - 0.19 12.1 1.0 1.6 9.2 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EPS28629.1 - 0.78 9.4 6.3 4.1 7.1 0.3 3.2 4 0 0 4 4 3 0 AAA domain CDP-OH_P_transf PF01066.21 EPS28631.1 - 8.8e-14 52.0 0.9 8.8e-14 52.0 0.9 1.8 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase ABC1 PF03109.16 EPS28633.1 - 2.2e-32 111.7 0.0 4.9e-32 110.6 0.0 1.6 1 0 0 1 1 1 1 ABC1 family UreF PF01730.16 EPS28634.1 - 7.8e-24 84.7 0.3 1.4e-23 83.9 0.3 1.4 1 0 0 1 1 1 1 UreF Ribosomal_L29 PF00831.23 EPS28634.1 - 0.13 12.2 0.1 0.26 11.3 0.1 1.4 1 0 0 1 1 1 0 Ribosomal L29 protein BRE1 PF08647.11 EPS28635.1 - 8.2e-29 99.5 12.7 8.2e-29 99.5 12.7 8.3 5 2 4 9 9 9 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 EPS28635.1 - 4.3e-10 39.3 7.8 7.5e-10 38.5 7.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EPS28635.1 - 2.1e-09 37.0 8.4 3.7e-09 36.3 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPS28635.1 - 5.8e-08 32.5 10.3 1e-07 31.7 10.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPS28635.1 - 8.2e-08 32.2 6.3 1.6e-07 31.2 6.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EPS28635.1 - 1.3e-07 31.3 8.3 2.2e-07 30.6 8.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EPS28635.1 - 1.5e-07 31.6 8.9 2.6e-07 30.9 8.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EPS28635.1 - 3.3e-06 27.0 10.5 5.5e-06 26.2 10.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EPS28635.1 - 0.00071 19.8 5.6 0.0039 17.4 5.0 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EPS28635.1 - 0.0019 18.3 6.7 0.0034 17.5 6.7 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DUF1272 PF06906.11 EPS28635.1 - 0.01 15.9 5.4 0.022 14.8 5.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_4 PF14570.6 EPS28635.1 - 0.025 14.3 7.4 0.2 11.5 8.1 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 EPS28635.1 - 0.053 13.7 6.6 0.12 12.6 6.6 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 TRAF_BIRC3_bd PF16673.5 EPS28635.1 - 0.08 12.8 0.4 0.08 12.8 0.4 5.3 4 2 2 6 6 5 0 TNF receptor-associated factor BIRC3 binding domain APG6_N PF17675.1 EPS28635.1 - 0.082 13.4 89.1 0.12 12.9 7.1 7.4 1 1 6 8 8 8 0 Apg6 coiled-coil region DUF3627 PF12299.8 EPS28635.1 - 0.14 12.3 3.9 1.4 9.0 1.0 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3627) ATG16 PF08614.11 EPS28635.1 - 0.3 11.3 90.3 0.11 12.7 24.7 5.2 2 2 2 4 4 4 0 Autophagy protein 16 (ATG16) zf-Nse PF11789.8 EPS28635.1 - 0.49 10.3 5.6 1.2 9.0 5.6 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Zn_ribbon_17 PF17120.5 EPS28635.1 - 0.5 10.0 4.8 0.96 9.1 4.8 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C2HC_2 PF13913.6 EPS28635.1 - 0.58 10.1 7.3 0.45 10.5 2.7 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Baculo_PEP_C PF04513.12 EPS28635.1 - 0.91 9.6 41.0 1.3 9.1 0.8 6.2 4 3 2 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-RING_6 PF14835.6 EPS28635.1 - 1.3 8.9 4.3 2.6 8.0 4.3 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein FYVE PF01363.21 EPS28635.1 - 1.6 8.9 12.1 22 5.3 11.3 2.4 1 1 1 2 2 2 0 FYVE zinc finger zf-C2H2_jaz PF12171.8 EPS28635.1 - 6.1 7.3 6.6 81 3.7 0.1 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Myb_DNA-bind_7 PF15963.5 EPS28636.1 - 3.1e-29 100.7 0.2 3.1e-29 100.7 0.2 2.2 1 1 1 2 2 2 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 EPS28636.1 - 2.9e-05 24.2 0.0 2.9e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain ANAPC15 PF15243.6 EPS28636.1 - 1.5 9.3 8.0 0.92 10.0 0.4 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 15 SARAF PF06682.12 EPS28637.1 - 4.6e-100 335.5 3.2 5.4e-100 335.3 3.2 1.0 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis MMM1 PF10296.9 EPS28638.1 - 2.1e-133 444.5 0.0 2.5e-133 444.2 0.0 1.0 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 ARD PF03079.14 EPS28639.1 - 6e-46 156.5 0.2 7.3e-46 156.2 0.2 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 EPS28639.1 - 1.5e-10 40.7 0.0 2.5e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EPS28639.1 - 1.8e-05 24.7 0.0 2.9e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 EPS28639.1 - 0.092 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Cupin GIDA PF01134.22 EPS28640.1 - 1.8e-154 514.6 0.0 2.3e-154 514.2 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 EPS28640.1 - 8.3e-67 225.4 0.1 1.2e-66 224.9 0.1 1.2 1 0 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 EPS28640.1 - 3.1e-06 26.8 1.3 5.2e-06 26.1 1.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPS28640.1 - 4e-06 26.3 0.4 7.8e-06 25.3 0.4 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EPS28640.1 - 0.0012 18.0 1.9 0.0012 18.0 1.9 2.0 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 EPS28640.1 - 0.0029 17.0 0.3 0.0073 15.6 0.3 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 EPS28640.1 - 0.033 12.9 0.7 0.31 9.7 0.5 2.1 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 EPS28640.1 - 0.039 13.0 0.0 0.073 12.1 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein DAO PF01266.24 EPS28640.1 - 0.061 12.9 3.2 1.4 8.5 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EPS28640.1 - 0.067 12.0 0.5 8.5 5.1 0.4 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Ammonium_transp PF00909.21 EPS28641.1 - 3.1e-115 385.0 30.5 3.6e-115 384.8 30.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family E1-E2_ATPase PF00122.20 EPS28643.1 - 3.3e-47 160.3 0.6 9.4e-47 158.9 0.6 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EPS28643.1 - 1.5e-43 148.7 2.9 2.9e-43 147.7 0.0 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EPS28643.1 - 2.4e-21 77.0 0.0 7.5e-21 75.4 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EPS28643.1 - 1.4e-17 63.1 0.0 2.8e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EPS28643.1 - 2.6e-13 49.9 0.0 4.8e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EPS28643.1 - 6.6e-05 22.8 1.3 0.00076 19.3 0.7 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Rad21_Rec8_N PF04825.13 EPS28644.1 - 3.3e-37 127.0 0.1 7e-37 126.0 0.1 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EPS28644.1 - 6.6e-08 31.7 0.4 1.5e-07 30.6 0.4 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein MFS_1 PF07690.16 EPS28645.1 - 2.3e-42 145.2 34.5 4.3e-42 144.3 27.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS28645.1 - 4.1e-12 45.7 4.6 4.1e-12 45.7 4.6 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EPS28645.1 - 3.8e-07 28.9 1.4 3.8e-07 28.9 1.4 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Bap31 PF05529.12 EPS28645.1 - 0.0052 16.6 0.1 0.023 14.6 0.1 2.1 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Hexokinase_2 PF03727.16 EPS28646.1 - 2.7e-79 266.0 0.0 4.2e-79 265.4 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 EPS28646.1 - 2.5e-73 246.3 0.0 3.2e-73 245.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase PLCC PF14466.6 EPS28646.1 - 0.067 13.3 0.0 0.49 10.5 0.0 2.1 2 0 0 2 2 2 0 PLAT/LH2 and C2-like Ca2+-binding lipoprotein SIR2 PF02146.17 EPS28647.1 - 1.3e-55 188.0 0.0 1.8e-55 187.6 0.0 1.2 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 EPS28647.1 - 0.025 14.3 0.0 0.27 11.0 0.0 2.1 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain COG4 PF08318.12 EPS28648.1 - 1.9e-126 421.7 0.0 2.6e-126 421.2 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein DUF4893 PF16233.5 EPS28648.1 - 0.094 12.3 0.0 0.26 10.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4893) Spc7 PF08317.11 EPS28648.1 - 0.25 10.2 0.5 0.51 9.2 0.5 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein TMF_TATA_bd PF12325.8 EPS28648.1 - 2.3 8.5 5.3 2.5 8.4 0.6 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Tom22 PF04281.13 EPS28649.1 - 0.052 13.3 0.0 0.056 13.2 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Gti1_Pac2 PF09729.9 EPS28657.1 - 1.1e-61 208.1 0.0 2e-61 207.2 0.0 1.5 2 0 0 2 2 2 1 Gti1/Pac2 family Mannosyl_trans3 PF11051.8 EPS28658.1 - 1.9e-63 214.4 0.0 1.7e-37 129.3 0.0 2.1 1 1 1 2 2 2 2 Mannosyltransferase putative Lin-8 PF03353.15 EPS28659.1 - 0.083 12.4 7.0 0.1 12.2 7.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Mem_trans PF03547.18 EPS28659.1 - 0.69 8.2 2.1 0.67 8.3 2.1 1.1 1 0 0 1 1 1 0 Membrane transport protein RR_TM4-6 PF06459.12 EPS28659.1 - 1.7 8.4 11.4 0.36 10.6 7.5 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 TP2 PF01254.18 EPS28659.1 - 2.6 8.7 26.8 1.2 9.8 11.9 2.2 1 1 1 2 2 2 0 Nuclear transition protein 2 Peptidase_S64 PF08192.11 EPS28659.1 - 3.1 6.2 8.8 3.5 6.0 8.8 1.0 1 0 0 1 1 1 0 Peptidase family S64 GREB1 PF15782.5 EPS28659.1 - 3.5 4.6 10.0 3.6 4.6 10.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SRP-alpha_N PF04086.13 EPS28659.1 - 5.2 6.9 14.6 6.7 6.5 14.6 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Hid1 PF12722.7 EPS28659.1 - 7.5 4.5 8.8 8.4 4.4 8.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FUSC PF04632.12 EPS28659.1 - 7.7 4.9 7.1 10 4.5 7.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Neur_chan_memb PF02932.16 EPS28659.1 - 8.1 6.4 10.8 11 6.0 10.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PAT1 PF09770.9 EPS28659.1 - 9 4.4 15.8 10 4.2 15.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ribophorin_I PF04597.14 EPS28660.1 - 4.9e-144 480.8 0.0 5.6e-144 480.6 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I ICAT PF06384.11 EPS28660.1 - 0.17 12.1 0.0 0.38 11.0 0.0 1.5 1 0 0 1 1 1 0 Beta-catenin-interacting protein ICAT Indigoidine_A PF04227.12 EPS28661.1 - 7.2e-118 393.2 0.1 1.1e-117 392.6 0.1 1.3 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.24 EPS28661.1 - 7.5e-18 64.9 0.0 1.7e-11 44.0 0.0 2.6 2 1 0 2 2 2 2 pfkB family carbohydrate kinase Flavokinase PF01687.17 EPS28663.1 - 2.9e-34 117.7 0.0 3.6e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Zn_clus PF00172.18 EPS28664.1 - 0.0083 16.2 9.2 0.017 15.2 9.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 EPS28664.1 - 0.17 11.9 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 PAS fold Aa_trans PF01490.18 EPS28666.1 - 7.7e-74 248.8 27.8 9e-74 248.6 27.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PilX_N PF14341.6 EPS28666.1 - 0.058 13.4 1.0 0.25 11.3 1.0 2.1 1 0 0 1 1 1 0 PilX N-terminal TatD_DNase PF01026.21 EPS28668.1 - 1e-51 175.8 0.0 1.2e-51 175.6 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase FMN_dh PF01070.18 EPS28669.1 - 4.3e-113 377.9 0.0 5.2e-113 377.6 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EPS28669.1 - 1.2e-17 63.8 0.0 2.4e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EPS28669.1 - 0.00015 21.1 0.0 0.00024 20.4 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 EPS28669.1 - 0.0043 16.1 0.2 0.015 14.3 0.1 1.7 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EPS28669.1 - 0.011 15.2 0.1 0.2 11.0 0.1 2.1 1 1 1 2 2 2 0 Nitronate monooxygenase ThiG PF05690.14 EPS28669.1 - 0.035 13.4 0.0 3.9 6.7 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Nup54_C PF18437.1 EPS28669.1 - 0.19 11.6 0.2 0.38 10.7 0.2 1.4 1 0 0 1 1 1 0 Nup54 C-terminal interacting domain SAP PF02037.27 EPS28670.1 - 7.6e-10 38.3 0.1 1.3e-09 37.6 0.1 1.4 1 0 0 1 1 1 1 SAP domain Asp PF00026.23 EPS28671.1 - 3.6e-66 223.7 3.2 4.4e-66 223.4 3.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EPS28671.1 - 9e-15 55.4 3.4 3.5e-11 43.6 4.2 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EPS28671.1 - 0.0004 21.0 0.0 0.48 11.1 0.0 3.1 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 EPS28671.1 - 0.0094 15.7 0.0 0.064 13.0 0.0 2.1 1 1 1 2 2 2 1 Xylanase inhibitor C-terminal Bac_rhamnosid6H PF17389.2 EPS28672.1 - 1.8e-15 57.0 0.0 3.2e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Glyco_hydro_2_N PF02837.18 EPS28672.1 - 0.014 15.4 0.0 0.033 14.1 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_36 PF17167.4 EPS28672.1 - 0.03 13.0 0.0 0.045 12.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain Bac_rhamnosid_N PF08531.10 EPS28672.1 - 0.048 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain 4HBT PF03061.22 EPS28673.1 - 0.00088 19.6 0.3 0.065 13.6 0.1 2.4 2 0 0 2 2 2 2 Thioesterase superfamily Imm61 PF15598.6 EPS28673.1 - 0.059 13.3 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 61 Methyltransf_2 PF00891.18 EPS28674.1 - 4.6e-15 55.5 0.0 6.8e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Rrf2 PF02082.20 EPS28674.1 - 0.031 14.6 0.0 0.075 13.4 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator MarR_2 PF12802.7 EPS28674.1 - 0.15 12.0 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 MarR family FAD_binding_3 PF01494.19 EPS28675.1 - 1.6e-09 37.5 0.0 1.8e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EPS28675.1 - 0.0048 17.1 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EPS28675.1 - 0.084 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Aminotran_1_2 PF00155.21 EPS28676.1 - 1.2e-42 146.5 0.0 1.4e-42 146.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.21 EPS28676.1 - 0.014 14.1 0.0 0.022 13.4 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-III LEM PF03020.15 EPS28676.1 - 0.11 12.1 0.0 0.84 9.3 0.0 2.4 2 0 0 2 2 2 0 LEM domain Beta_elim_lyase PF01212.21 EPS28676.1 - 0.16 11.2 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase p450 PF00067.22 EPS28677.1 - 7e-34 117.3 0.0 9.1e-34 117.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-C2H2 PF00096.26 EPS28678.1 - 0.0025 18.2 24.5 0.029 14.8 1.6 4.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EPS28678.1 - 0.04 14.4 0.4 0.04 14.4 0.4 3.5 3 0 0 3 3 3 0 Zinc-finger double domain PyrI_C PF02748.15 EPS28678.1 - 0.096 12.6 3.0 2 8.4 0.4 2.5 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_4 PF13894.6 EPS28678.1 - 0.1 13.5 21.3 0.38 11.7 1.0 4.9 4 0 0 4 4 4 0 C2H2-type zinc finger zf-MYST PF17772.1 EPS28678.1 - 0.29 10.8 1.8 6.5 6.4 0.3 2.5 2 0 0 2 2 2 0 MYST family zinc finger domain zf-CHCC PF10276.9 EPS28678.1 - 0.33 11.0 5.2 5.6 7.1 0.5 2.4 2 0 0 2 2 2 0 Zinc-finger domain zf-C2H2_jaz PF12171.8 EPS28678.1 - 4.3 7.7 21.4 0.53 10.6 4.9 4.7 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-FCS PF06467.14 EPS28678.1 - 4.5 7.3 7.8 7.1 6.7 0.1 2.7 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif DSPc PF00782.20 EPS28680.1 - 7.1e-26 90.6 0.0 1e-25 90.1 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EPS28680.1 - 0.0023 18.2 0.0 0.004 17.4 0.0 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 EPS28680.1 - 0.04 13.5 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase IBR PF01485.21 EPS28680.1 - 0.049 13.9 1.1 1 9.6 0.2 2.6 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain c-SKI_SMAD_bind PF08782.10 EPS28680.1 - 0.09 13.0 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 c-SKI Smad4 binding domain Vfa1 PF08432.10 EPS28682.1 - 1.6e-61 207.8 16.3 1.7e-61 207.7 16.3 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.14 EPS28682.1 - 0.017 13.5 9.3 0.015 13.6 9.3 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4228 PF14009.6 EPS28682.1 - 0.22 11.9 3.9 0.28 11.5 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) NPR3 PF03666.13 EPS28682.1 - 0.22 10.3 10.4 0.26 10.0 10.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF5093 PF17011.5 EPS28682.1 - 0.45 10.8 10.3 0.047 14.0 5.7 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF5093) DDHD PF02862.17 EPS28682.1 - 0.65 10.1 4.4 0.78 9.9 4.4 1.2 1 0 0 1 1 1 0 DDHD domain Neur_chan_memb PF02932.16 EPS28682.1 - 1.1 9.2 5.2 1.3 9.0 5.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PPL5 PF18168.1 EPS28682.1 - 2.2 7.5 10.0 2.7 7.2 10.0 1.2 1 0 0 1 1 1 0 Prim-pol family 5 DUF4775 PF16001.5 EPS28682.1 - 2.7 7.3 23.5 3.4 7.0 23.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) RR_TM4-6 PF06459.12 EPS28682.1 - 4.2 7.1 16.9 5.3 6.8 16.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 EPS28682.1 - 6.9 5.3 11.6 8.3 5.0 11.6 1.1 1 0 0 1 1 1 0 Presenilin Ycf1 PF05758.12 EPS28682.1 - 9.2 4.0 11.8 11 3.7 11.8 1.0 1 0 0 1 1 1 0 Ycf1 Ndc1_Nup PF09531.10 EPS28683.1 - 1.3e-184 615.3 5.0 3e-183 610.8 5.0 2.0 1 1 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Syntaxin_2 PF14523.6 EPS28684.1 - 1.4e-26 92.8 3.0 1.4e-26 92.8 3.0 2.6 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 EPS28684.1 - 3.6e-13 49.3 1.5 3.6e-13 49.3 1.5 1.9 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 EPS28684.1 - 1.6e-07 31.2 12.6 8.4e-07 28.9 12.6 1.9 1 1 0 1 1 1 1 Syntaxin Prominin PF05478.11 EPS28684.1 - 0.012 13.6 5.7 0.015 13.3 5.7 1.1 1 0 0 1 1 1 0 Prominin Synaptobrevin PF00957.21 EPS28684.1 - 0.072 12.9 2.5 0.16 11.8 1.5 2.1 2 1 0 2 2 2 0 Synaptobrevin T3SSipB PF16535.5 EPS28684.1 - 0.13 12.8 12.8 0.15 12.5 9.1 2.5 1 1 0 2 2 2 0 Type III cell invasion protein SipB Nre_C PF04895.12 EPS28684.1 - 0.15 12.0 2.3 0.24 11.3 0.0 2.3 3 0 0 3 3 3 0 Archaeal Nre, C-terminal DUF883 PF05957.13 EPS28684.1 - 0.31 11.7 12.3 0.38 11.4 0.1 3.0 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Cyto_heme_lyase PF01265.17 EPS28685.1 - 7.7e-39 134.0 3.3 4.5e-35 121.7 0.3 2.8 2 1 0 2 2 2 2 Cytochrome c/c1 heme lyase MDD_C PF18376.1 EPS28686.1 - 1e-66 224.2 0.0 1.4e-66 223.8 0.0 1.2 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 EPS28686.1 - 3.3e-09 36.8 0.5 3.3e-09 36.8 0.5 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain LIF_OSM PF01291.17 EPS28686.1 - 0.071 13.3 0.4 0.19 11.9 0.1 1.8 2 0 0 2 2 2 0 LIF / OSM family DUF1772 PF08592.11 EPS28687.1 - 6e-31 107.6 7.6 7.3e-31 107.3 7.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) NAD_binding_9 PF13454.6 EPS28688.1 - 1.1e-29 103.4 0.4 1e-26 93.8 0.0 3.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding Formyl_trans_N PF00551.19 EPS28688.1 - 9e-09 35.3 0.0 1.8e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase Pyr_redox_3 PF13738.6 EPS28688.1 - 4.5e-08 32.7 0.0 9e-06 25.2 0.0 3.2 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EPS28688.1 - 8.5e-07 28.5 0.0 0.0087 15.3 0.0 2.8 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EPS28688.1 - 6.7e-06 25.5 0.0 0.033 13.3 0.0 2.5 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EPS28688.1 - 1.5e-05 24.8 0.8 0.014 15.0 0.3 2.9 2 1 1 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EPS28688.1 - 8.2e-05 21.9 0.1 0.046 12.8 0.1 2.7 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.6 EPS28688.1 - 0.02 15.1 0.0 0.36 11.1 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EPS28688.1 - 0.22 10.2 0.1 3.3 6.3 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein MFS_1 PF07690.16 EPS28689.1 - 9.5e-21 74.1 49.5 9.5e-21 74.1 49.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pro-kuma_activ PF09286.11 EPS28690.1 - 1.9e-50 170.9 0.0 4.3e-50 169.7 0.0 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain IKI3 PF04762.12 EPS28691.1 - 0 1027.9 0.0 0 1027.7 0.0 1.1 1 0 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 EPS28691.1 - 0.007 16.6 0.3 27 5.2 0.0 4.5 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Gmad1 PF10647.9 EPS28691.1 - 0.052 13.3 0.0 7.2 6.3 0.0 2.5 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain TPR_1 PF00515.28 EPS28691.1 - 1.2 9.1 6.4 0.5 10.3 1.6 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat COX7C PF02935.16 EPS28692.1 - 3.9e-23 81.5 3.1 4.9e-23 81.2 3.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc rRNA_proc-arch PF13234.6 EPS28693.1 - 7.1e-87 291.8 0.0 1.7e-86 290.5 0.0 1.7 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.12 EPS28693.1 - 4.8e-56 188.9 1.9 9.5e-56 188.0 1.9 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 EPS28693.1 - 8e-18 64.8 0.2 2.2e-17 63.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPS28693.1 - 4.2e-06 27.1 0.0 1.3e-05 25.5 0.0 1.9 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPS28693.1 - 2.3e-05 24.5 0.0 5.1e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 EPS28693.1 - 0.006 15.7 0.0 0.015 14.3 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein ATPase_2 PF01637.18 EPS28693.1 - 0.029 14.3 0.0 0.096 12.6 0.0 1.9 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_22 PF13401.6 EPS28693.1 - 0.12 12.6 0.0 0.32 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain PmbA_TldD PF01523.16 EPS28693.1 - 0.14 12.0 0.1 0.43 10.4 0.1 1.8 1 0 0 1 1 1 0 Putative modulator of DNA gyrase Cut8 PF08559.10 EPS28694.1 - 2.1e-80 269.8 0.0 2.6e-80 269.5 0.0 1.0 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein DUF3984 PF13136.6 EPS28695.1 - 5.8e-113 377.6 23.3 7.3e-113 377.3 23.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3984) OTCace_N PF02729.21 EPS28696.1 - 1.9e-45 154.5 0.1 3.7e-45 153.6 0.1 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 EPS28696.1 - 2.1e-45 154.6 0.0 3.2e-45 154.0 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain LEA_2 PF03168.13 EPS28697.1 - 1e-11 45.3 1.2 0.00057 20.4 0.0 4.3 4 0 0 4 4 4 3 Late embryogenesis abundant protein ALS_ss_C PF10369.9 EPS28698.1 - 1e-15 57.7 0.0 1.8e-14 53.7 0.0 2.4 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.25 EPS28698.1 - 6.1e-13 48.3 0.1 1.2e-12 47.4 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 EPS28698.1 - 2.6e-08 33.6 0.0 4.6e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 ACT domain UPF0058 PF01893.16 EPS28698.1 - 0.013 15.8 0.3 0.023 15.0 0.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0058 MEIOC PF15189.6 EPS28698.1 - 0.017 14.7 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 Meiosis-specific coiled-coil domain-containing protein MEIOC ACT_6 PF13740.6 EPS28698.1 - 0.042 13.8 0.0 9.6 6.3 0.0 2.6 2 0 0 2 2 2 0 ACT domain Limkain-b1 PF11608.8 EPS28698.1 - 0.048 13.7 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Limkain b1 IF2_assoc PF08364.11 EPS28698.1 - 0.24 11.7 0.3 0.45 10.8 0.3 1.4 1 0 0 1 1 1 0 Bacterial translation initiation factor IF-2 associated region KH_1 PF00013.29 EPS28699.1 - 1.8e-08 34.1 0.1 3.2e-06 26.9 0.0 2.8 3 0 0 3 3 3 2 KH domain DEAD PF00270.29 EPS28700.1 - 2.8e-15 56.6 0.0 4.7e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPS28700.1 - 3.8e-12 46.5 0.0 1.7e-09 38.0 0.0 2.7 3 0 0 3 3 3 2 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 EPS28700.1 - 3.2e-07 31.0 0.9 5.6e-07 30.2 0.3 1.8 2 0 0 2 2 2 1 RecQ zinc-binding PPR_2 PF13041.6 EPS28701.1 - 6.8e-10 39.0 0.0 0.051 13.8 0.0 3.9 3 0 0 3 3 3 3 PPR repeat family PPR PF01535.20 EPS28701.1 - 0.00068 19.7 0.0 0.93 9.9 0.0 4.0 4 0 0 4 4 4 1 PPR repeat TPR_14 PF13428.6 EPS28701.1 - 0.27 12.2 6.3 1.8 9.6 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat MRP-S25 PF13741.6 EPS28702.1 - 2.4e-87 292.3 2.7 2.8e-87 292.1 2.7 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 EPS28702.1 - 0.0022 18.2 0.7 4.1 7.7 0.0 2.9 3 0 0 3 3 3 2 Mitochondrial ribosomal protein S23 SOG2 PF10428.9 EPS28703.1 - 4.9e-108 362.5 0.0 4.9e-108 362.5 0.0 4.8 4 1 0 4 4 4 1 RAM signalling pathway protein LRR_8 PF13855.6 EPS28703.1 - 2.8e-14 52.6 14.7 1.5e-07 31.0 1.0 2.7 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 EPS28703.1 - 1.3e-09 38.2 6.0 0.002 18.5 1.7 3.6 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EPS28703.1 - 0.0048 17.2 4.2 32 5.6 0.1 5.6 5 0 0 5 5 5 0 Leucine Rich Repeat Cytochrom_C_2 PF01322.20 EPS28703.1 - 0.21 12.5 0.2 14 6.6 0.1 2.6 2 0 0 2 2 2 0 Cytochrome C' LRR_6 PF13516.6 EPS28703.1 - 0.62 10.3 9.6 19 5.6 0.1 5.0 6 0 0 6 6 6 0 Leucine Rich repeat Peptidase_S10 PF00450.22 EPS28704.1 - 1.5e-58 199.2 0.0 1.4e-57 196.0 0.0 2.3 1 1 0 1 1 1 1 Serine carboxypeptidase Tcp11 PF05794.13 EPS28705.1 - 6.4e-115 384.7 2.4 7.8e-115 384.5 2.4 1.1 1 0 0 1 1 1 1 T-complex protein 11 Ydc2-catalyt PF09159.10 EPS28706.1 - 1.6e-82 277.4 0.0 2e-82 277.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.13 EPS28706.1 - 0.0011 19.1 0.0 3 7.9 0.0 3.3 3 0 0 3 3 3 1 Poxvirus A22 protein SAP PF02037.27 EPS28706.1 - 0.04 13.7 0.1 0.15 11.8 0.0 2.1 2 0 0 2 2 2 0 SAP domain Glypican PF01153.19 EPS28708.1 - 5.2 5.8 7.8 1.3 7.7 4.0 1.7 1 1 1 2 2 2 0 Glypican Zn_clus PF00172.18 EPS28709.1 - 0.03 14.4 14.8 0.41 10.8 9.4 2.5 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPS28710.1 - 2.4e-29 102.2 0.1 3.4e-29 101.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain EMP24_GP25L PF01105.24 EPS28711.1 - 2.7e-50 170.8 0.8 3.2e-50 170.6 0.8 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2721 PF11026.8 EPS28711.1 - 1.6 8.6 6.7 0.21 11.5 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) SANT_DAMP1_like PF16282.5 EPS28712.1 - 4.7e-31 106.8 4.5 8.6e-31 106.0 4.5 1.5 1 0 0 1 1 1 1 SANT/Myb-like domain of DAMP1 DMAP1 PF05499.12 EPS28712.1 - 2e-05 24.5 9.6 0.001 19.0 8.7 3.1 1 1 1 2 2 2 1 DNA methyltransferase 1-associated protein 1 (DMAP1) Myb_DNA-binding PF00249.31 EPS28712.1 - 0.0067 16.6 0.0 0.029 14.6 0.0 2.1 1 1 0 1 1 1 1 Myb-like DNA-binding domain DUF1704 PF08014.11 EPS28712.1 - 0.029 13.4 0.4 0.064 12.3 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1704) Meth_synt_2 PF01717.18 EPS28714.1 - 4.8e-149 496.0 0.0 5.5e-146 485.9 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EPS28714.1 - 4.7e-117 391.0 0.0 3.5e-109 365.1 0.0 2.7 3 0 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain Steroid_dh PF02544.16 EPS28715.1 - 9.9e-14 51.6 0.5 4.6e-05 23.4 0.1 3.6 3 1 0 3 3 3 3 3-oxo-5-alpha-steroid 4-dehydrogenase Ufd2P_core PF10408.9 EPS28716.1 - 3.5e-204 680.0 13.5 4.3e-204 679.7 13.5 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 EPS28716.1 - 6e-28 96.8 3.4 7.7e-28 96.5 0.9 2.6 2 0 0 2 2 2 1 U-box domain SgrT PF15894.5 EPS28716.1 - 0.084 12.9 0.6 0.35 10.9 0.2 2.2 2 0 0 2 2 2 0 Inhibitor of glucose uptake transporter SgrT EF-1_beta_acid PF10587.9 EPS28716.1 - 3.4 8.2 8.8 11 6.5 0.1 3.5 3 0 0 3 3 3 0 Eukaryotic elongation factor 1 beta central acidic region Bap31_Bap29_C PF18035.1 EPS28716.1 - 8.5 6.5 7.3 1.4 9.0 2.3 2.3 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF1977 PF09320.11 EPS28717.1 - 3.8e-31 107.5 0.0 6.7e-31 106.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.31 EPS28717.1 - 1.1e-22 79.9 1.2 1.9e-22 79.1 1.2 1.4 1 0 0 1 1 1 1 DnaJ domain Aim19 PF10315.9 EPS28718.1 - 3.2e-05 24.2 0.1 3.7e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 Altered inheritance of mitochondria protein 19 CTP_transf_like PF01467.26 EPS28719.1 - 4.4e-06 27.0 0.0 1.1e-05 25.6 0.0 1.7 2 1 0 2 2 2 1 Cytidylyltransferase-like vMSA PF00695.19 EPS28719.1 - 0.088 11.9 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Proteasome PF00227.26 EPS28720.1 - 1.7e-41 141.8 0.0 2e-41 141.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit TUG-UBL1 PF11470.8 EPS28721.1 - 9.9e-25 86.6 0.0 3.5e-24 84.8 0.1 2.0 2 0 0 2 2 2 1 TUG ubiquitin-like domain UBX PF00789.20 EPS28721.1 - 9.4e-05 22.5 0.0 0.00026 21.1 0.0 1.8 1 0 0 1 1 1 1 UBX domain FAM101 PF15068.6 EPS28721.1 - 0.098 12.6 0.9 0.17 11.8 0.9 1.4 1 0 0 1 1 1 0 FAM101 family Ribosomal_L36e PF01158.18 EPS28722.1 - 4.3e-38 129.5 6.1 4.8e-38 129.3 6.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e HTH_38 PF13936.6 EPS28722.1 - 0.029 14.1 0.8 0.29 10.9 0.2 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain NatB_MDM20 PF09797.9 EPS28723.1 - 3.1e-93 312.8 0.0 1.1e-92 310.9 0.0 1.9 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.6 EPS28723.1 - 0.015 15.8 4.2 1.6 9.3 0.0 4.1 6 0 0 6 6 6 0 Tetratricopeptide repeat MTCP1 PF08991.10 EPS28724.1 - 1.5e-05 25.1 1.7 2.1e-05 24.7 1.7 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 EPS28724.1 - 2.2e-05 24.4 6.9 3.7e-05 23.7 6.9 1.4 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.9 EPS28724.1 - 0.023 15.0 4.3 0.049 13.9 4.2 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 zf-C3HC4 PF00097.25 EPS28725.1 - 5.4e-09 35.8 4.2 5.4e-09 35.8 4.2 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EPS28725.1 - 2.3e-08 34.2 6.5 2.3e-08 34.2 6.5 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 EPS28725.1 - 3e-07 30.2 3.7 3e-07 30.2 3.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EPS28725.1 - 3e-07 30.2 5.9 3e-07 30.2 5.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EPS28725.1 - 6.6e-07 29.4 7.0 6.6e-07 29.4 7.0 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EPS28725.1 - 1.5e-06 28.1 5.8 1.5e-06 28.1 5.8 1.8 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EPS28725.1 - 7.7e-06 25.8 5.9 7.7e-06 25.8 5.9 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EPS28725.1 - 0.0049 16.9 2.4 0.0049 16.9 2.4 2.2 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 EPS28725.1 - 0.011 15.6 8.8 0.16 11.8 3.4 2.3 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 EPS28725.1 - 0.014 15.2 4.3 0.014 15.2 4.3 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EPS28725.1 - 0.015 15.6 6.1 0.015 15.6 6.1 2.4 2 1 0 2 2 2 0 RING-H2 zinc finger domain Baculo_IE-1 PF05290.11 EPS28725.1 - 0.22 11.5 1.5 0.37 10.7 1.5 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) IBR PF01485.21 EPS28725.1 - 1.2 9.4 8.5 5.3 7.3 2.5 2.8 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain DZR PF12773.7 EPS28725.1 - 1.8 8.7 13.1 5.5e+02 0.7 13.1 2.8 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_4 PF14570.6 EPS28725.1 - 5.9 6.8 13.3 0.054 13.3 2.5 2.7 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain Peptidase_S9 PF00326.21 EPS28726.1 - 2e-34 118.9 0.6 6.7e-34 117.2 0.0 2.0 3 0 0 3 3 3 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EPS28726.1 - 2.2e-06 27.1 0.2 0.015 14.5 0.0 2.3 2 0 0 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 EPS28726.1 - 2.5e-05 24.0 0.0 6.9e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 EPS28726.1 - 0.00024 21.0 0.0 0.0006 19.7 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 EPS28726.1 - 0.00064 19.8 0.0 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Peptidase_S15 PF02129.18 EPS28726.1 - 0.00076 19.1 0.2 0.24 11.0 0.8 2.4 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 EPS28726.1 - 0.00099 17.9 0.0 0.0028 16.4 0.0 1.9 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 EPS28726.1 - 0.0013 18.7 0.0 0.024 14.6 0.0 2.3 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.20 EPS28726.1 - 0.0027 17.4 0.4 0.53 9.9 0.0 2.7 2 1 1 3 3 3 1 alpha/beta hydrolase fold FSH1 PF03959.13 EPS28726.1 - 0.0046 16.6 0.0 0.0087 15.7 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) LIP PF03583.14 EPS28726.1 - 0.02 14.2 0.4 3.7 6.8 0.4 2.1 2 0 0 2 2 2 0 Secretory lipase COesterase PF00135.28 EPS28726.1 - 0.17 10.7 0.2 0.26 10.1 0.2 1.2 1 0 0 1 1 1 0 Carboxylesterase family WD40 PF00400.32 EPS28727.1 - 6.6e-21 74.2 10.2 6.1e-06 26.9 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS28727.1 - 0.0019 18.4 0.0 0.011 16.1 0.0 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EPS28727.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 WD40-like domain Proteasome PF00227.26 EPS28728.1 - 3.1e-37 127.9 0.0 4.2e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Sigma54_AID PF00309.20 EPS28728.1 - 0.13 12.2 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 factor, Activator interacting domain (AID) UCH PF00443.29 EPS28729.1 - 5.7e-25 88.3 0.2 5e-24 85.2 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EPS28729.1 - 1.6e-12 47.6 0.2 3.9e-12 46.3 0.1 1.7 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 EPS28729.1 - 0.0023 17.6 0.5 0.012 15.2 0.4 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TolA_bind_tri PF16331.5 EPS28730.1 - 0.076 13.1 1.3 0.22 11.6 1.3 1.8 1 0 0 1 1 1 0 TolA binding protein trimerisation WD40 PF00400.32 EPS28731.1 - 6.4e-54 178.7 11.9 3.4e-06 27.7 1.4 13.0 12 1 0 12 12 12 10 WD domain, G-beta repeat Utp13 PF08625.11 EPS28731.1 - 1.7e-49 167.4 0.2 2.8e-49 166.7 0.2 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 EPS28731.1 - 3.5e-13 49.7 5.3 0.14 12.4 0.1 8.0 5 4 1 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EPS28731.1 - 0.0014 17.5 4.5 1.9 7.1 0.2 4.9 3 2 1 4 4 4 2 Nup133 N terminal like Nup160 PF11715.8 EPS28731.1 - 0.0033 16.2 12.5 1.5 7.4 0.1 5.9 4 2 3 7 7 7 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EPS28731.1 - 0.0069 15.4 0.4 8.3 5.3 0.0 4.2 3 1 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EPS28731.1 - 0.011 15.1 0.0 6.4 6.0 0.0 2.9 3 0 0 3 3 3 0 WD40-like domain DUF1699 PF08004.11 EPS28731.1 - 0.037 13.7 0.0 0.23 11.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1699) Cytochrom_D1 PF02239.16 EPS28731.1 - 0.038 12.5 0.1 0.077 11.5 0.1 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain Frtz PF11768.8 EPS28731.1 - 0.042 12.2 0.0 0.19 10.0 0.0 1.9 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz G-patch_2 PF12656.7 EPS28732.1 - 2.8e-24 85.0 0.1 1.3e-23 82.9 0.1 2.3 1 0 0 1 1 1 1 G-patch domain G-patch PF01585.23 EPS28732.1 - 0.018 15.0 0.2 0.044 13.7 0.2 1.7 1 0 0 1 1 1 0 G-patch domain Myb_DNA-bind_6 PF13921.6 EPS28733.1 - 5.9e-17 61.7 0.1 1.8e-16 60.2 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain HSA PF07529.13 EPS28733.1 - 6e-11 42.5 1.0 6e-11 42.5 1.0 3.6 3 0 0 3 3 3 1 HSA Myb_DNA-binding PF00249.31 EPS28733.1 - 0.00022 21.3 0.2 0.0005 20.2 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain WD40 PF00400.32 EPS28734.1 - 3.6e-10 40.2 0.0 1.3 10.0 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2_C PF09173.11 EPS28735.1 - 1.4e-34 118.2 0.4 3.4e-34 117.0 0.4 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 EPS28735.1 - 2.5e-22 79.4 0.1 1.6e-21 76.8 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EPS28735.1 - 4.4e-13 49.4 0.0 9.5e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 EPS28735.1 - 0.0094 15.9 0.1 0.087 12.7 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 EPS28735.1 - 0.012 15.7 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Peptidase_M48_N PF16491.5 EPS28736.1 - 7.4e-65 218.3 7.0 7.4e-65 218.3 7.0 1.8 2 1 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 EPS28736.1 - 1.4e-43 148.9 0.4 2.3e-43 148.2 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M48 Peptidase_M56 PF05569.11 EPS28736.1 - 0.011 14.9 0.5 0.023 13.9 0.5 1.5 1 1 0 1 1 1 0 BlaR1 peptidase M56 DUF4538 PF15061.6 EPS28736.1 - 0.019 14.7 1.4 0.07 12.9 1.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) RNA_polI_A14 PF08203.11 EPS28737.1 - 0.0042 17.8 0.6 0.048 14.4 0.0 2.2 2 0 0 2 2 2 1 Yeast RNA polymerase I subunit RPA14 Rrn6 PF10214.9 EPS28737.1 - 0.029 12.9 2.7 0.023 13.2 2.7 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF3381 PF11861.8 EPS28737.1 - 0.34 10.7 13.6 0.48 10.2 13.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) PGA2 PF07543.12 EPS28737.1 - 1.3 9.0 12.3 1.8 8.5 12.3 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 Presenilin PF01080.17 EPS28737.1 - 7.9 5.1 4.9 7 5.3 4.9 1.1 1 0 0 1 1 1 0 Presenilin Ribosomal_L34 PF00468.17 EPS28738.1 - 6.9e-12 45.1 13.3 1e-11 44.6 13.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 LAT PF15234.6 EPS28738.1 - 1 9.1 4.4 1.3 8.7 4.4 1.3 1 1 0 1 1 1 0 Linker for activation of T-cells Peptidase_M16_C PF05193.21 EPS28739.1 - 2.6e-19 69.9 0.0 9.9e-16 58.3 0.0 2.8 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EPS28739.1 - 8.1e-07 29.1 0.2 9e-06 25.7 0.0 2.7 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) DNA_pol_phi PF04931.13 EPS28739.1 - 0.15 10.1 15.4 0.024 12.8 11.5 1.7 2 0 0 2 2 2 0 DNA polymerase phi PRESAN PF09687.10 EPS28739.1 - 0.28 11.7 2.1 0.99 10.0 1.0 2.2 2 0 0 2 2 2 0 Plasmodium RESA N-terminal POM121 PF15229.6 EPS28739.1 - 0.51 10.0 0.0 0.51 10.0 0.0 1.6 2 0 0 2 2 2 0 POM121 family Sigma70_ner PF04546.13 EPS28739.1 - 5.2 6.9 13.1 1.3 8.9 8.4 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region Zw10 PF06248.13 EPS28740.1 - 7.2e-09 34.8 3.1 1.6e-08 33.6 0.7 2.2 2 1 0 2 2 2 1 Centromere/kinetochore Zw10 Dsl1_C PF11989.8 EPS28740.1 - 1.5e-06 28.1 0.0 3.5e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal BUD22 PF09073.10 EPS28740.1 - 0.066 12.5 9.2 0.12 11.6 9.2 1.3 1 0 0 1 1 1 0 BUD22 YjcZ PF13990.6 EPS28740.1 - 0.11 11.9 2.5 0.21 11.0 2.5 1.4 1 0 0 1 1 1 0 YjcZ-like protein NPV_P10 PF05531.12 EPS28740.1 - 0.12 12.9 0.6 15 6.1 0.1 3.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Aurora-A_bind PF09041.10 EPS28740.1 - 0.14 12.2 0.2 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Aurora-A binding TMF_TATA_bd PF12325.8 EPS28740.1 - 0.89 9.8 4.8 0.42 10.8 0.7 2.7 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding WD40 PF00400.32 EPS28741.1 - 1.6e-21 76.2 21.2 3e-07 31.0 0.2 7.0 7 1 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.12 EPS28741.1 - 1.6e-20 73.3 0.3 3e-20 72.5 0.3 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 EPS28741.1 - 3.7e-05 22.6 0.3 0.0042 15.8 0.0 2.4 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Ribosomal_S13 PF00416.22 EPS28742.1 - 2.3e-21 76.5 0.2 3.9e-19 69.3 0.2 2.0 1 1 0 1 1 1 1 Ribosomal protein S13/S18 Ntox8 PF15545.6 EPS28742.1 - 0.023 14.8 0.1 0.034 14.2 0.1 1.4 1 0 0 1 1 1 0 Bacterial toxin 8 Pro_isomerase PF00160.21 EPS28743.1 - 2.7e-49 167.4 0.3 3.4e-49 167.1 0.3 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DEAD PF00270.29 EPS28744.1 - 1.6e-48 164.8 0.0 6.4e-48 162.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPS28744.1 - 1.1e-32 112.6 0.0 3.1e-32 111.2 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPS28744.1 - 0.019 14.9 0.0 0.036 14.1 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EPS28744.1 - 0.091 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 EPS28744.1 - 0.098 12.0 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Glyco_transf_28 PF03033.20 EPS28746.1 - 2.1e-21 76.4 0.0 4.4e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 EPS28746.1 - 0.0023 16.8 0.1 0.004 16.0 0.1 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase VPS13_C PF16909.5 EPS28746.1 - 0.004 16.9 2.1 0.007 16.2 0.4 2.2 3 0 0 3 3 3 1 Vacuolar-sorting-associated 13 protein C-terminal zf-Tim10_DDP PF02953.15 EPS28746.1 - 0.18 11.5 0.1 0.34 10.6 0.1 1.3 1 0 0 1 1 1 0 Tim10/DDP family zinc finger RTA1 PF04479.13 EPS28747.1 - 6e-57 192.6 14.9 6e-57 192.6 14.9 2.0 1 1 1 2 2 2 1 RTA1 like protein gpD PF02925.16 EPS28747.1 - 0.03 14.3 0.4 0.052 13.5 0.4 1.4 1 0 0 1 1 1 0 Bacteriophage scaffolding protein D Zn_clus PF00172.18 EPS28748.1 - 2.8e-09 36.9 12.1 6.5e-09 35.8 8.6 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EPS28748.1 - 6.5e-06 25.2 3.7 8.5e-06 24.8 3.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.13 EPS28749.1 - 1.7e-59 200.9 17.0 2.8e-59 200.2 17.0 1.3 1 0 0 1 1 1 1 RTA1 like protein gpD PF02925.16 EPS28749.1 - 0.007 16.3 0.4 0.012 15.6 0.4 1.3 1 0 0 1 1 1 1 Bacteriophage scaffolding protein D Thioesterase PF00975.20 EPS28750.1 - 0.00027 21.1 0.1 0.00053 20.2 0.1 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.7 EPS28750.1 - 0.0007 20.3 0.4 0.0012 19.5 0.4 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.12 EPS28750.1 - 0.0025 17.8 0.2 0.0049 16.8 0.2 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) PGAP1 PF07819.13 EPS28750.1 - 0.0048 16.6 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein DUF2974 PF11187.8 EPS28750.1 - 0.006 16.2 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.13 EPS28750.1 - 0.012 15.4 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EPS28750.1 - 0.024 13.9 0.0 0.044 13.0 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 TSSC4 PF15264.6 EPS28750.1 - 0.028 14.7 0.7 0.068 13.4 0.0 1.9 2 0 0 2 2 2 0 Tumour suppressing sub-chromosomal transferable candidate 4 Lipase_3 PF01764.25 EPS28750.1 - 0.061 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) ADH_zinc_N_2 PF13602.6 EPS28751.1 - 4.9e-12 47.1 0.0 1.7e-11 45.3 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EPS28751.1 - 2e-09 37.5 0.0 5.3e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPS28751.1 - 3.8e-09 36.4 0.1 7e-09 35.5 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Toxin_29 PF08116.11 EPS28752.1 - 0.0062 16.5 30.8 0.044 13.8 7.1 3.8 3 1 0 3 3 3 2 PhTx neurotoxin family UPF0506 PF11703.8 EPS28752.1 - 0.011 16.1 3.0 0.011 16.1 3.0 3.5 3 1 0 3 3 3 0 UPF0506 Colipase PF01114.18 EPS28752.1 - 0.015 15.0 2.9 0.015 15.0 2.9 3.3 3 0 0 3 3 3 0 Colipase, N-terminal domain INSIG PF07281.12 EPS28754.1 - 2.9e-76 255.8 2.2 4.3e-76 255.3 2.2 1.2 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) AICARFT_IMPCHas PF01808.18 EPS28755.1 - 2.6e-90 302.9 0.0 4.4e-90 302.1 0.0 1.4 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 EPS28755.1 - 9.4e-26 89.8 0.0 2.3e-25 88.6 0.0 1.7 1 0 0 1 1 1 1 MGS-like domain Beta-lactamase PF00144.24 EPS28756.1 - 1.2e-35 123.4 0.0 2e-35 122.6 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase DEAD PF00270.29 EPS28757.1 - 4.6e-38 130.7 0.2 9.1e-38 129.8 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPS28757.1 - 2.2e-23 82.7 0.0 1.1e-21 77.3 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EPS28757.1 - 6.3e-05 22.3 0.0 9.5e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 EPS28757.1 - 0.00015 21.8 0.0 0.00029 20.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EPS28757.1 - 0.00075 19.9 0.1 0.0017 18.7 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EPS28757.1 - 0.0077 16.0 0.1 0.015 15.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 EPS28757.1 - 0.17 11.3 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain BatA PF07584.11 EPS28759.1 - 0.13 12.6 0.2 0.25 11.7 0.2 1.4 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal Usp PF00582.26 EPS28760.1 - 3.7e-22 79.3 0.2 1.2e-21 77.8 0.0 2.0 2 0 0 2 2 2 1 Universal stress protein family MIF4G PF02854.19 EPS28761.1 - 4.5e-51 173.5 0.0 7.8e-51 172.7 0.0 1.4 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 EPS28761.1 - 1.7e-21 76.2 0.5 4.3e-21 74.9 0.5 1.7 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 TB2_DP1_HVA22 PF03134.19 EPS28763.1 - 2.8e-24 84.9 6.9 4.4e-24 84.2 6.9 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Bacteriocin_IIc PF10439.9 EPS28763.1 - 1.4 9.1 3.0 1.6 8.9 0.7 2.1 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide RCDG1 PF15725.5 EPS28763.1 - 3.5 8.1 7.4 7.3 7.1 7.4 1.5 1 0 0 1 1 1 0 Renal cancer differentiation gene 1 protein TANGO2 PF05742.12 EPS28764.1 - 1.4e-73 248.0 0.0 1.6e-73 247.9 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 PP2C_C PF07830.13 EPS28764.1 - 0.015 15.7 0.0 0.03 14.8 0.0 1.4 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain Cellulase PF00150.18 EPS28765.1 - 2.1e-54 184.9 2.4 2.7e-54 184.5 2.4 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 EPS28765.1 - 2.1e-13 50.0 7.7 2.1e-13 50.0 7.7 2.8 2 0 0 2 2 2 1 Fungal cellulose binding domain SSF PF00474.17 EPS28765.1 - 0.13 11.1 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 Sodium:solute symporter family Hyaluronidase_1 PF07212.11 EPS28766.1 - 0.18 11.0 0.1 0.21 10.8 0.1 1.0 1 0 0 1 1 1 0 Hyaluronidase protein (HylP) CYSTM PF12734.7 EPS28766.1 - 1.8 8.9 22.7 4.4 7.7 22.7 1.8 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance DUF1768 PF08719.11 EPS28768.1 - 1.9e-53 181.0 0.1 2.2e-53 180.8 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) BPL_N PF09825.9 EPS28769.1 - 5.1e-152 506.3 0.0 6.3e-152 506.0 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 EPS28769.1 - 1.3e-24 86.6 0.0 2e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family GATase_3 PF07685.14 EPS28769.1 - 0.053 13.1 0.1 0.096 12.3 0.1 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain CHCH PF06747.13 EPS28770.1 - 2.6e-07 30.6 8.0 3.9e-07 30.0 8.0 1.3 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 EPS28770.1 - 0.00057 19.8 1.7 0.11 12.5 0.3 2.4 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 EPS28770.1 - 0.0057 16.6 5.4 0.062 13.3 0.4 2.1 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like Mgm101p PF06420.12 EPS28771.1 - 1e-85 285.5 0.0 1.3e-85 285.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 MS_channel PF00924.18 EPS28772.1 - 4.1e-19 69.0 0.3 6.9e-19 68.2 0.3 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 EPS28772.1 - 0.0032 16.9 0.3 0.0085 15.6 0.3 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EPS28772.1 - 0.011 15.6 0.1 0.037 14.0 0.1 1.9 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.6 EPS28772.1 - 0.027 13.9 0.1 0.086 12.4 0.1 1.9 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 EPS28772.1 - 0.039 14.4 0.0 0.099 13.1 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair OAD_gamma PF04277.13 EPS28772.1 - 1.2 9.7 4.7 5.9 7.6 4.7 2.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain zf-RING_2 PF13639.6 EPS28776.1 - 6.4e-13 48.8 5.4 1.1e-12 48.1 5.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EPS28776.1 - 8.7e-10 38.2 2.9 1.6e-09 37.3 2.9 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EPS28776.1 - 2.2e-08 33.8 5.3 3.7e-08 33.1 5.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPS28776.1 - 8.1e-08 32.0 3.0 1.4e-07 31.3 3.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EPS28776.1 - 8.1e-06 26.0 8.3 3e-05 24.2 8.3 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EPS28776.1 - 0.00034 20.4 1.3 0.00065 19.5 1.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EPS28776.1 - 0.00036 20.3 9.5 0.00088 19.1 7.3 2.5 2 1 1 3 3 3 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EPS28776.1 - 0.00044 20.2 2.1 0.00085 19.2 2.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EPS28776.1 - 0.0005 20.1 1.2 0.0012 18.8 1.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EPS28776.1 - 0.0013 18.7 3.2 0.0013 18.7 3.2 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 EPS28776.1 - 0.019 14.7 3.2 0.019 14.7 3.2 1.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 EPS28776.1 - 0.15 12.4 1.4 0.26 11.6 1.4 1.4 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.6 EPS28776.1 - 0.33 11.2 4.3 1.1 9.5 4.4 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 EPS28776.1 - 5.3 7.3 5.7 39 4.5 5.7 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain Aminotran_1_2 PF00155.21 EPS28777.1 - 2.4e-85 286.9 0.0 3.5e-85 286.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Syntaxin-18_N PF10496.9 EPS28778.1 - 1.9e-11 44.1 1.2 2.1e-10 40.7 0.1 2.6 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 EPS28778.1 - 0.00018 21.5 0.1 0.00054 19.9 0.0 1.8 2 0 0 2 2 2 1 SNARE domain FAM104 PF15434.6 EPS28778.1 - 0.33 11.5 2.1 2 9.0 0.1 2.7 2 1 0 2 2 2 0 Family 104 BLOC1_2 PF10046.9 EPS28778.1 - 0.37 11.1 5.4 0.23 11.8 1.4 2.5 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.10 EPS28778.1 - 0.38 10.9 1.6 8.6 6.5 1.9 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family CENP-H PF05837.12 EPS28778.1 - 0.69 10.4 4.9 0.47 10.9 0.5 2.7 3 0 0 3 3 3 0 Centromere protein H (CENP-H) DUF16 PF01519.16 EPS28778.1 - 1.2 9.6 4.1 0.75 10.3 1.6 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF16 TPR_1 PF00515.28 EPS28779.1 - 5.1e-13 48.2 2.7 4.6e-06 26.2 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EPS28779.1 - 4.7e-12 45.0 4.0 0.0007 19.5 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EPS28779.1 - 1.7e-08 34.6 0.4 4.8e-05 23.6 0.1 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EPS28779.1 - 1.3e-07 31.3 0.1 0.00061 19.8 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EPS28779.1 - 5.6e-06 26.9 1.1 0.004 17.8 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EPS28779.1 - 1.9e-05 24.3 0.5 0.00094 19.0 0.1 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EPS28779.1 - 4.2e-05 23.9 0.4 3.1 8.6 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EPS28779.1 - 4.5e-05 23.0 0.3 0.00083 19.0 0.1 2.8 1 1 1 2 2 2 1 TPR repeat PB1 PF00564.24 EPS28779.1 - 0.0001 22.1 0.0 0.00018 21.4 0.0 1.4 1 0 0 1 1 1 1 PB1 domain TPR_9 PF13371.6 EPS28779.1 - 0.0034 17.5 0.1 2.5 8.3 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_4 PF07721.14 EPS28779.1 - 0.032 14.8 3.5 60 4.7 0.0 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 EPS28779.1 - 0.068 14.0 0.7 4.4 8.4 0.1 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EPS28779.1 - 0.34 10.8 4.0 2.8 7.9 0.1 3.8 4 1 1 5 5 4 0 Tetratricopeptide repeat AbiEii PF08843.11 EPS28780.1 - 9e-05 22.5 0.1 0.00016 21.7 0.1 1.4 1 1 0 1 1 1 1 Nucleotidyl transferase AbiEii toxin, Type IV TA system DUF2007 PF09413.10 EPS28781.1 - 0.0095 16.1 0.0 0.024 14.8 0.0 1.6 2 0 0 2 2 2 1 Putative prokaryotic signal transducing protein HMA PF00403.26 EPS28782.1 - 1.9e-15 57.0 0.1 3.8e-15 56.1 0.1 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.20 EPS28782.1 - 1.3e-09 38.3 0.0 2e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Pkinase PF00069.25 EPS28783.1 - 4.6e-62 209.8 0.0 6.3e-62 209.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS28783.1 - 4.4e-27 95.0 0.0 6.5e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EPS28783.1 - 0.0082 15.5 0.1 0.014 14.8 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EPS28783.1 - 0.024 14.0 0.0 0.1 11.9 0.0 1.8 1 1 0 2 2 2 0 Kinase-like Haspin_kinase PF12330.8 EPS28783.1 - 0.024 13.6 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EPS28783.1 - 0.081 12.8 0.1 0.081 12.8 0.1 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF3987 PF13148.6 EPS28783.1 - 1.5 7.7 5.8 2.1 7.3 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Rrn6 PF10214.9 EPS28783.1 - 2.2 6.7 9.3 2.9 6.3 9.3 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Peptidase_C14 PF00656.22 EPS28784.1 - 0.01 15.8 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Herpes_pp85 PF04637.12 EPS28784.1 - 0.011 14.2 1.2 0.016 13.7 1.2 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) HI0933_like PF03486.14 EPS28785.1 - 0.13 10.9 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein RFXA_RFXANK_bdg PF15289.6 EPS28785.1 - 0.18 12.1 3.2 0.084 13.2 0.8 1.7 2 0 0 2 2 2 0 Regulatory factor X-associated C-terminal binding domain Methyltransf_28 PF02636.17 EPS28786.1 - 1.3e-82 277.4 0.0 1.6e-82 277.1 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Rhodanese PF00581.20 EPS28787.1 - 1.7e-12 47.8 0.0 2.1e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Ribosomal_S21 PF01165.20 EPS28788.1 - 1.1e-08 34.6 0.3 1.9e-08 33.9 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 SOG2 PF10428.9 EPS28788.1 - 0.043 13.0 13.7 0.057 12.6 13.7 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Hamartin PF04388.12 EPS28788.1 - 0.081 11.6 12.0 0.12 11.1 12.0 1.1 1 0 0 1 1 1 0 Hamartin protein ORC6 PF05460.13 EPS28788.1 - 0.17 11.1 9.6 0.21 10.8 9.6 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Macoilin PF09726.9 EPS28788.1 - 0.2 10.2 5.7 0.23 10.0 5.7 1.1 1 0 0 1 1 1 0 Macoilin family Ndc1_Nup PF09531.10 EPS28788.1 - 0.26 10.0 7.6 0.26 9.9 7.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TPPII_N PF12583.8 EPS28788.1 - 0.32 11.6 10.7 0.52 10.9 10.7 1.2 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal DUF908 PF06012.12 EPS28788.1 - 0.53 9.7 10.8 0.78 9.1 10.8 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) GET2 PF08690.10 EPS28788.1 - 0.59 9.8 6.4 0.8 9.3 6.4 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Presenilin PF01080.17 EPS28788.1 - 0.75 8.5 2.2 0.87 8.3 2.2 1.1 1 0 0 1 1 1 0 Presenilin KAR9 PF08580.10 EPS28788.1 - 2.2 6.7 17.4 0.2 10.2 0.6 2.1 2 0 0 2 2 2 0 Yeast cortical protein KAR9 Nucleo_P87 PF07267.11 EPS28788.1 - 3.7 6.3 6.1 5 5.9 6.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 FAM53 PF15242.6 EPS28789.1 - 0.11 12.2 0.2 0.18 11.6 0.2 1.4 1 0 0 1 1 1 0 Family of FAM53 PGI PF00342.19 EPS28790.1 - 6.3e-240 796.8 0.2 7.4e-240 796.6 0.2 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase PWI PF01480.17 EPS28791.1 - 1.7e-16 60.2 1.2 5.7e-16 58.6 0.9 2.1 2 0 0 2 2 2 1 PWI domain RRM_1 PF00076.22 EPS28791.1 - 0.0066 16.2 0.0 0.018 14.9 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LCD1 PF09798.9 EPS28791.1 - 0.2 10.1 0.7 0.26 9.7 0.7 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein MR_MLE_C PF13378.6 EPS28792.1 - 5.2e-59 199.5 0.0 8.4e-59 198.8 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EPS28792.1 - 7.5e-06 26.2 0.0 1.6e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain TIM21 PF08294.11 EPS28793.1 - 3.4e-41 140.5 0.0 4.2e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.10 EPS28793.1 - 1.8e-05 24.4 0.0 6.7e-05 22.6 0.0 1.8 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 ArfGap PF01412.18 EPS28794.1 - 3.3e-34 117.5 0.2 5.2e-34 116.8 0.2 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Herpes_ICP4_N PF03584.15 EPS28794.1 - 0.052 13.4 0.1 0.14 12.0 0.1 1.7 1 0 0 1 1 1 0 Herpesvirus ICP4-like protein N-terminal region Fungal_trans PF04082.18 EPS28795.1 - 0.00081 18.5 1.3 0.0016 17.6 1.3 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Dmrt1 PF12374.8 EPS28795.1 - 0.18 12.3 2.5 0.42 11.1 2.5 1.7 1 0 0 1 1 1 0 Double-sex mab3 related transcription factor 1 FPN1 PF06963.12 EPS28796.1 - 3.5e-98 329.0 16.4 4.8e-98 328.6 16.4 1.2 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Kelch_3 PF13415.6 EPS28797.1 - 2.5e-28 97.8 5.8 1.1e-07 31.9 0.1 6.1 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.6 EPS28797.1 - 1.3e-26 92.3 14.6 1.9e-11 43.8 0.0 6.8 5 2 1 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 EPS28797.1 - 3.6e-16 58.8 5.5 0.0033 17.7 0.1 6.2 5 1 1 6 6 6 4 Kelch motif Kelch_1 PF01344.25 EPS28797.1 - 1.2e-14 53.5 8.1 2.1e-05 24.0 0.0 6.3 6 1 0 6 6 6 5 Kelch motif Kelch_5 PF13854.6 EPS28797.1 - 2.7e-13 49.6 0.6 0.0056 16.6 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 EPS28797.1 - 1.9e-11 43.4 9.3 0.00035 20.4 0.4 6.0 6 1 0 6 6 6 4 Kelch motif Pterin_bind PF00809.22 EPS28799.1 - 4.4e-82 275.4 0.0 5.5e-82 275.1 0.0 1.1 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 EPS28799.1 - 3e-36 124.3 0.0 6.3e-36 123.3 0.0 1.6 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) NMO PF03060.15 EPS28800.1 - 3.1e-54 184.6 2.6 4.4e-54 184.1 2.6 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EPS28800.1 - 1.2e-11 44.2 2.1 2.1e-11 43.4 2.1 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EPS28800.1 - 1.9e-07 30.5 2.4 3e-07 29.8 2.4 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 EPS28800.1 - 0.00036 19.8 2.4 0.0007 18.8 2.4 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 EPS28800.1 - 0.044 13.0 0.6 0.082 12.1 0.6 1.5 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Transp_cyt_pur PF02133.15 EPS28801.1 - 1.5e-45 155.8 33.0 1.8e-45 155.5 33.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Cation_efflux PF01545.21 EPS28802.1 - 1.4e-51 175.1 3.7 1.8e-51 174.7 3.7 1.1 1 0 0 1 1 1 1 Cation efflux family BPD_transp_2 PF02653.16 EPS28802.1 - 0.018 14.2 0.3 0.018 14.2 0.3 2.3 2 1 0 2 2 2 0 Branched-chain amino acid transport system / permease component Plant_vir_prot PF01307.17 EPS28802.1 - 0.067 13.4 2.2 0.25 11.6 0.4 2.7 2 0 0 2 2 2 0 Plant viral movement protein DUF4396 PF14342.6 EPS28803.1 - 2.4e-41 141.4 2.6 3.3e-40 137.7 2.6 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4396) HSP70 PF00012.20 EPS28805.1 - 0.0031 15.8 0.0 0.0045 15.2 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein Peptidase_M22 PF00814.25 EPS28805.1 - 0.084 12.6 0.0 0.12 12.0 0.0 1.4 1 1 0 1 1 1 0 Glycoprotease family eIF3g PF12353.8 EPS28806.1 - 4.1e-44 150.0 3.7 6.1e-44 149.4 3.7 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 EPS28806.1 - 1.4e-16 60.0 0.0 2.3e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_7 PF18586.1 EPS28806.1 - 0.02 15.2 0.5 0.058 13.7 0.2 1.8 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 Ribosomal_L27_C PF18471.1 EPS28806.1 - 0.082 12.3 0.6 0.14 11.6 0.6 1.3 1 0 0 1 1 1 0 Ribosomal L27 protein C-terminal domain Nup35_RRM_2 PF14605.6 EPS28806.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif NDT80_PhoG PF05224.12 EPS28808.1 - 2.3e-36 125.8 0.0 3.2e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family AMP-binding PF00501.28 EPS28811.1 - 9.3e-87 291.3 0.0 1.4e-86 290.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EPS28811.1 - 7e-05 23.7 0.1 0.00029 21.8 0.1 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Methyltransf_16 PF10294.9 EPS28812.1 - 7.4e-09 35.6 0.0 0.0019 18.0 0.0 2.9 2 1 1 3 3 3 2 Lysine methyltransferase SCO1-SenC PF02630.14 EPS28812.1 - 0.11 12.5 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 SCO1/SenC DUF2415 PF10313.9 EPS28813.1 - 1.4e-14 53.7 0.0 5.5e-14 51.8 0.0 2.1 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) HSP70 PF00012.20 EPS28814.1 - 2.3e-264 878.1 15.7 2.7e-264 877.9 15.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EPS28814.1 - 2.1e-14 53.1 4.6 2.1e-13 49.8 1.3 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 EPS28814.1 - 0.0028 17.4 0.0 0.0097 15.7 0.0 1.9 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF4363 PF14276.6 EPS28814.1 - 0.43 10.7 3.7 0.9 9.7 3.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) SUIM_assoc PF16619.5 EPS28814.1 - 3.4 7.8 9.2 4.1 7.5 6.6 2.5 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 FtsA PF14450.6 EPS28814.1 - 7 7.1 12.3 2.2 8.7 0.3 4.0 3 3 0 3 3 3 0 Cell division protein FtsA RRN3 PF05327.11 EPS28814.1 - 9.6 4.6 9.8 15 4.0 9.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 PRIMA1 PF16101.5 EPS28815.1 - 3.5 7.7 16.3 0.23 11.5 7.4 2.5 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 Mito_fiss_reg PF05308.11 EPS28815.1 - 5.3 7.1 9.1 12 5.9 7.1 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator DUF1682 PF07946.14 EPS28817.1 - 4.9 6.3 7.6 9.2 5.4 7.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DSHCT PF08148.12 EPS28818.1 - 3.1e-52 176.5 0.5 8.4e-52 175.1 0.5 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain Ski2_N PF17911.1 EPS28818.1 - 6.5e-40 136.1 0.1 1.3e-39 135.1 0.1 1.5 1 0 0 1 1 1 1 Ski2 N-terminal region rRNA_proc-arch PF13234.6 EPS28818.1 - 3.9e-20 72.9 0.0 6.9e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.29 EPS28818.1 - 3.2e-18 66.1 0.0 7e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPS28818.1 - 8.1e-06 26.2 0.0 1.9e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPS28818.1 - 2.1e-05 24.6 0.0 4.3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit IBN_N PF03810.19 EPS28819.1 - 6.7e-17 61.2 0.1 6.9e-14 51.5 0.0 3.6 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cse1 PF08506.10 EPS28819.1 - 1.3e-09 37.4 0.0 2.7e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Cse1 RTP1_C1 PF10363.9 EPS28819.1 - 0.00044 20.4 0.3 0.073 13.2 0.1 3.1 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 CAS_CSE1 PF03378.15 EPS28819.1 - 0.00087 17.9 0.2 0.57 8.6 0.0 2.9 3 0 0 3 3 3 2 CAS/CSE protein, C-terminus HEAT_2 PF13646.6 EPS28819.1 - 0.019 15.4 0.3 5.4 7.5 0.0 3.7 2 1 1 3 3 3 0 HEAT repeats Xpo1 PF08389.12 EPS28819.1 - 0.024 14.7 1.6 0.65 10.0 0.0 3.7 4 1 0 4 4 4 0 Exportin 1-like protein RIX1 PF08167.12 EPS28819.1 - 0.047 13.4 0.2 2.8 7.7 0.0 3.8 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis HEAT_EZ PF13513.6 EPS28819.1 - 0.26 11.8 2.0 25 5.5 0.6 4.5 4 1 0 4 4 4 0 HEAT-like repeat BUD22 PF09073.10 EPS28819.1 - 1.6 8.0 5.2 2.4 7.4 5.2 1.2 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 EPS28819.1 - 3.1 7.2 8.3 5.1 6.4 8.3 1.3 1 0 0 1 1 1 0 SDA1 DNA_pol_phi PF04931.13 EPS28819.1 - 7.7 4.5 14.6 19 3.2 14.6 1.6 1 0 0 1 1 1 0 DNA polymerase phi RRM_1 PF00076.22 EPS28821.1 - 3e-10 39.8 0.0 6.1e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EPS28821.1 - 5.1e-06 26.4 0.0 1.1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EPS28821.1 - 0.022 14.6 0.0 0.055 13.3 0.0 1.7 1 0 0 1 1 1 0 Occluded RNA-recognition motif DUF4651 PF15513.6 EPS28821.1 - 0.18 11.6 0.0 0.36 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4651) DUF2046 PF09755.9 EPS28822.1 - 0.0048 16.2 1.4 0.081 12.1 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) bZIP_2 PF07716.15 EPS28822.1 - 0.049 13.7 8.3 0.077 13.1 1.3 2.3 2 0 0 2 2 2 0 Basic region leucine zipper SlyX PF04102.12 EPS28822.1 - 0.064 13.9 3.2 5.1 7.8 0.2 2.5 2 0 0 2 2 2 0 SlyX AIP3 PF03915.13 EPS28822.1 - 0.11 11.5 2.9 0.53 9.3 0.2 2.1 2 0 0 2 2 2 0 Actin interacting protein 3 Dimerisation PF08100.11 EPS28822.1 - 0.12 12.4 0.4 0.34 11.0 0.1 1.9 2 0 0 2 2 2 0 Dimerisation domain FlaC_arch PF05377.11 EPS28822.1 - 0.25 11.7 3.0 0.31 11.4 0.3 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DivIC PF04977.15 EPS28822.1 - 0.3 10.9 4.1 1.8 8.4 1.2 2.2 2 0 0 2 2 2 0 Septum formation initiator PspB PF06667.12 EPS28822.1 - 0.92 9.6 3.0 0.36 10.9 0.3 1.8 2 0 0 2 2 2 0 Phage shock protein B CPSase_L_D2 PF02786.17 EPS28825.1 - 1.7e-107 357.7 0.0 9e-84 280.2 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 EPS28825.1 - 4.3e-41 140.1 0.1 1.2e-40 138.6 0.0 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Dala_Dala_lig_C PF07478.13 EPS28825.1 - 1.1e-17 64.3 0.4 2.2e-08 33.9 0.1 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EPS28825.1 - 7.5e-17 61.4 0.0 3.6e-07 29.9 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 EPS28825.1 - 3.8e-13 49.3 0.0 1.9e-05 24.4 0.0 2.9 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_5 PF13549.6 EPS28825.1 - 2.2e-05 24.0 0.3 0.057 12.9 0.0 3.1 3 0 0 3 3 3 2 ATP-grasp domain GARS_A PF01071.19 EPS28825.1 - 0.0019 18.0 0.0 0.15 11.8 0.0 2.6 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Peptidase_U40 PF10464.9 EPS28825.1 - 0.016 14.9 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Peptidase U40 SET PF00856.28 EPS28826.1 - 2e-16 60.9 0.0 4.1e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 EPS28826.1 - 8.5e-08 32.2 8.3 8.5e-08 32.2 8.3 2.0 2 0 0 2 2 2 1 MYND finger AAA PF00004.29 EPS28828.1 - 1.6e-54 183.9 0.0 2.8e-43 147.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 EPS28828.1 - 8.1e-29 99.9 0.6 1.9e-28 98.6 0.6 1.7 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 EPS28828.1 - 2.5e-15 56.0 0.6 1e-07 31.6 0.1 2.7 2 0 0 2 2 2 2 AAA+ lid domain NACHT PF05729.12 EPS28828.1 - 1.1e-07 31.9 0.6 0.0001 22.3 0.0 3.3 3 0 0 3 3 3 1 NACHT domain AAA_2 PF07724.14 EPS28828.1 - 1.4e-07 31.8 0.0 0.0089 16.2 0.0 2.8 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EPS28828.1 - 1.8e-06 28.5 12.6 0.026 14.9 0.1 5.2 2 2 3 6 6 6 2 AAA ATPase domain TsaE PF02367.17 EPS28828.1 - 2.2e-06 27.7 0.2 0.0048 16.9 0.1 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 EPS28828.1 - 1.1e-05 25.3 0.0 0.014 15.1 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 EPS28828.1 - 2.9e-05 23.9 0.3 0.024 14.4 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 EPS28828.1 - 0.00016 22.2 0.0 0.58 10.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 EPS28828.1 - 0.00038 20.5 0.1 1.6 8.7 0.0 3.2 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EPS28828.1 - 0.00044 20.5 2.6 1.5 9.1 0.2 4.0 2 2 1 3 3 3 2 AAA domain RNA_helicase PF00910.22 EPS28828.1 - 0.00064 20.1 0.0 1.1 9.7 0.0 2.7 2 0 0 2 2 2 2 RNA helicase Zeta_toxin PF06414.12 EPS28828.1 - 0.00067 19.0 0.1 0.2 10.9 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_14 PF13173.6 EPS28828.1 - 0.00079 19.5 0.0 1.1 9.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EPS28828.1 - 0.0021 18.2 0.0 0.19 11.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EPS28828.1 - 0.0024 17.4 0.6 0.12 11.9 0.0 2.8 3 0 0 3 3 2 1 P-loop containing dynein motor region AAA_28 PF13521.6 EPS28828.1 - 0.0035 17.6 0.2 1.7 8.9 0.0 3.0 3 0 0 3 3 3 1 AAA domain TIP49 PF06068.13 EPS28828.1 - 0.0044 16.3 0.1 1.1 8.4 0.0 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_19 PF13245.6 EPS28828.1 - 0.0074 16.6 0.2 0.091 13.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EPS28828.1 - 0.0096 15.5 3.8 1.5 8.4 0.1 3.6 2 2 0 3 3 3 1 AAA domain ABC_tran PF00005.27 EPS28828.1 - 0.012 16.1 0.0 7.4 7.1 0.1 2.8 2 0 0 2 2 2 0 ABC transporter Mg_chelatase PF01078.21 EPS28828.1 - 0.015 14.7 0.2 0.77 9.1 0.1 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.15 EPS28828.1 - 0.028 14.4 0.1 0.38 10.6 0.0 2.2 2 0 0 2 2 2 0 NTPase Sigma54_activat PF00158.26 EPS28828.1 - 0.035 13.8 0.0 2.2 7.9 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain PEX-2N PF09263.10 EPS28828.1 - 0.072 13.4 1.0 5.6 7.3 0.1 2.7 2 1 0 2 2 2 0 Peroxisome biogenesis factor 1, N-terminal KAP_NTPase PF07693.14 EPS28828.1 - 0.076 12.2 1.0 0.53 9.5 0.1 2.3 1 1 1 2 2 2 0 KAP family P-loop domain ATPase PF06745.13 EPS28828.1 - 0.083 12.2 0.2 13 5.1 0.0 2.3 2 0 0 2 2 2 0 KaiC Cytidylate_kin2 PF13189.6 EPS28828.1 - 0.083 13.0 0.1 6.8 6.8 0.0 3.0 3 0 0 3 3 3 0 Cytidylate kinase-like family DUF815 PF05673.13 EPS28828.1 - 0.12 11.5 0.0 1.6 7.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF2075 PF09848.9 EPS28828.1 - 0.21 10.8 0.0 9.1 5.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) MCM PF00493.23 EPS28829.1 - 4.1e-103 343.3 0.0 7e-103 342.5 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EPS28829.1 - 2.7e-31 108.1 1.2 4.8e-31 107.2 1.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EPS28829.1 - 2.1e-21 76.1 1.5 6e-21 74.7 1.5 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EPS28829.1 - 4.4e-20 72.2 2.6 1.2e-19 70.9 2.6 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EPS28829.1 - 2.2e-07 30.5 0.0 1.8e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EPS28829.1 - 1.8e-06 28.0 0.0 5.7e-06 26.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_2 PF17863.1 EPS28829.1 - 0.0099 15.7 0.1 0.026 14.3 0.1 1.7 1 0 0 1 1 1 1 AAA lid domain AAA_3 PF07726.11 EPS28829.1 - 0.017 14.9 0.0 0.074 12.9 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EPS28829.1 - 0.02 15.3 2.6 8.7 6.7 0.0 3.5 3 0 0 3 3 3 0 AAA ATPase domain Sigma54_activat PF00158.26 EPS28829.1 - 0.079 12.7 0.1 0.76 9.5 0.0 2.4 3 0 0 3 3 3 0 Sigma-54 interaction domain Mg_chelatase_C PF13335.6 EPS28829.1 - 0.11 13.2 1.2 0.41 11.3 0.3 2.6 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI C-terminal EGF_CA PF07645.15 EPS28830.1 - 1.5e-05 25.1 7.9 1.5e-05 25.1 7.9 2.1 2 1 0 2 2 2 1 Calcium-binding EGF domain Plasmod_Pvs28 PF06247.11 EPS28830.1 - 0.00017 21.8 2.1 0.00017 21.8 2.1 2.0 2 0 0 2 2 2 1 Pvs28 EGF domain EGF_3 PF12947.7 EPS28830.1 - 0.0004 20.5 6.5 0.0014 18.8 6.5 2.0 1 1 0 1 1 1 1 EGF domain cEGF PF12662.7 EPS28830.1 - 0.0056 16.6 0.0 0.0056 16.6 0.0 2.8 3 0 0 3 3 3 1 Complement Clr-like EGF-like FXa_inhibition PF14670.6 EPS28830.1 - 0.034 14.4 6.1 0.034 14.4 6.1 2.4 2 2 0 2 2 2 0 Coagulation Factor Xa inhibitory site Carb_kinase PF01256.17 EPS28831.1 - 1.7e-55 188.2 0.4 2e-54 184.6 0.4 2.0 1 1 0 1 1 1 1 Carbohydrate kinase SPT2 PF08243.11 EPS28832.1 - 3.2e-06 27.6 22.7 3.2e-06 27.6 22.7 2.7 2 1 0 2 2 2 1 SPT2 chromatin protein Ribosomal_60s PF00428.19 EPS28833.1 - 3.1e-27 95.0 9.4 3.6e-27 94.8 9.4 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein EF-hand_14 PF17959.1 EPS28833.1 - 0.11 12.9 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 EF-hand domain DUF3138 PF11336.8 EPS28833.1 - 0.2 10.3 1.9 0.19 10.3 1.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Ribosomal_S19 PF00203.21 EPS28834.1 - 1.7e-33 114.3 0.3 2.4e-33 113.9 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 AMP-binding PF00501.28 EPS28835.1 - 1.1e-94 317.4 0.0 1.3e-94 317.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EPS28835.1 - 1.8e-11 44.9 0.2 4.7e-11 43.5 0.1 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.6 EPS28836.1 - 7.8e-23 81.3 0.1 1.4e-22 80.4 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EPS28836.1 - 5.6e-06 26.0 0.0 7.8e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EPS28836.1 - 0.03 13.4 0.0 0.059 12.5 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Aldo_ket_red PF00248.21 EPS28840.1 - 6.2e-46 156.9 0.1 3.4e-38 131.5 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family MIOX PF05153.15 EPS28841.1 - 9.7e-125 415.1 1.5 1.2e-124 414.8 1.5 1.1 1 0 0 1 1 1 1 Myo-inositol oxygenase HD PF01966.22 EPS28841.1 - 0.011 16.0 0.1 0.4 10.9 0.1 2.6 1 1 0 1 1 1 0 HD domain DUF1796 PF08795.10 EPS28841.1 - 0.069 13.1 0.3 0.13 12.2 0.3 1.5 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) FAT PF02259.23 EPS28844.1 - 4.1e-131 437.3 1.2 4.1e-131 437.3 1.2 2.2 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 EPS28844.1 - 8.4e-71 238.7 0.1 1.6e-70 237.8 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 EPS28844.1 - 1.3e-66 223.5 3.5 7.3e-61 204.8 0.8 4.9 4 1 1 5 5 5 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 EPS28844.1 - 4.6e-42 142.4 6.3 6.1e-42 142.1 0.2 3.7 3 0 0 3 3 2 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 EPS28844.1 - 1.6e-14 54.1 5.9 0.017 15.5 0.0 8.7 8 1 1 9 9 8 3 HEAT repeats HEAT_EZ PF13513.6 EPS28844.1 - 2.3e-14 53.5 13.1 0.00027 21.4 0.0 11.2 10 2 2 12 12 12 2 HEAT-like repeat FATC PF02260.20 EPS28844.1 - 4.6e-13 48.7 1.0 1.1e-12 47.6 1.0 1.7 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 EPS28844.1 - 2.3e-09 36.7 18.4 0.006 16.7 0.0 11.3 13 0 0 13 13 11 2 HEAT repeat Cnd1 PF12717.7 EPS28844.1 - 6.6e-05 23.0 0.2 27 4.8 0.0 5.7 3 1 2 5 5 5 0 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EPS28844.1 - 0.00018 21.1 2.0 2.3 7.7 0.0 5.0 5 0 0 5 5 5 1 CLASP N terminal Tti2 PF10521.9 EPS28844.1 - 0.00024 20.7 0.7 1.8 8.0 0.2 4.7 3 1 0 4 4 4 1 Tti2 family MMS19_C PF12460.8 EPS28844.1 - 0.00032 19.9 9.0 0.23 10.5 0.0 4.7 4 1 0 4 4 4 2 RNAPII transcription regulator C-terminal UME PF08064.13 EPS28844.1 - 0.004 17.0 5.9 5.4 7.0 0.0 6.5 5 2 1 6 6 6 1 UME (NUC010) domain TPR_14 PF13428.6 EPS28844.1 - 0.088 13.7 10.5 1.2 10.1 0.1 6.3 4 2 2 6 6 6 0 Tetratricopeptide repeat Inhibitor_G39P PF11417.8 EPS28844.1 - 0.12 12.9 0.0 6.2 7.4 0.0 3.3 3 0 0 3 3 3 0 Loader and inhibitor of phage G40P Sec7_N PF12783.7 EPS28844.1 - 0.13 12.2 0.1 5.4 6.9 0.0 3.5 3 0 0 3 3 2 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Epimerase PF01370.21 EPS28845.1 - 8e-19 68.1 0.0 1.2e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EPS28845.1 - 4.8e-12 45.5 0.0 6.3e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EPS28845.1 - 7.9e-11 41.9 0.0 1.3e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EPS28845.1 - 3.1e-08 33.1 0.0 2.5e-07 30.1 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 EPS28845.1 - 1.1e-05 25.4 0.0 2.9e-05 24.0 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EPS28845.1 - 3.1e-05 23.3 0.0 0.00017 20.9 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.25 EPS28845.1 - 0.00042 19.8 0.0 0.00066 19.2 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 EPS28845.1 - 0.0038 16.8 0.2 0.0092 15.6 0.1 1.9 2 1 0 2 2 2 1 NmrA-like family KR PF08659.10 EPS28845.1 - 0.013 15.5 0.0 0.027 14.4 0.0 1.5 1 1 0 1 1 1 0 KR domain RmlD_sub_bind PF04321.17 EPS28845.1 - 0.11 11.6 0.1 0.52 9.4 0.0 2.1 2 1 0 2 2 2 0 RmlD substrate binding domain Mit_ribos_Mrp51 PF11709.8 EPS28846.1 - 3e-110 369.3 0.0 3.4e-110 369.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit Styelin PF17562.2 EPS28846.1 - 0.14 12.5 0.2 29 5.1 0.0 2.9 3 0 0 3 3 3 0 Styelin Ribosomal_S17e PF00833.18 EPS28847.1 - 1.2e-60 202.8 1.0 1.5e-60 202.5 1.0 1.1 1 0 0 1 1 1 1 Ribosomal S17 RPAP2_Rtr1 PF04181.13 EPS28848.1 - 5.9e-20 71.4 0.0 1.1e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family FAP PF07174.11 EPS28848.1 - 1.3 8.4 7.8 12 5.2 7.1 2.3 2 1 0 2 2 2 0 Fibronectin-attachment protein (FAP) SH3_9 PF14604.6 EPS28849.1 - 1.2e-09 37.8 1.2 1.8e-09 37.3 0.2 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.28 EPS28849.1 - 2e-09 36.9 0.9 3.4e-09 36.2 0.1 1.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 EPS28849.1 - 6.7e-07 28.9 0.0 1.4e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain CWC25 PF12542.8 EPS28850.1 - 2.6e-16 60.4 0.1 2.6e-16 60.4 0.1 3.4 3 1 0 3 3 3 1 Pre-mRNA splicing factor Adaptin_N PF01602.20 EPS28851.1 - 8.8e-119 397.4 9.5 1.1e-118 397.1 9.5 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EPS28851.1 - 6.1e-57 192.2 9.4 9.3e-56 188.3 0.3 3.7 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EPS28851.1 - 2.5e-13 50.2 8.2 0.00015 22.1 0.0 5.4 4 1 1 5 5 5 4 HEAT repeats HEAT PF02985.22 EPS28851.1 - 7.3e-11 41.4 6.6 0.002 18.2 0.0 6.2 7 0 0 7 7 7 3 HEAT repeat Atx10homo_assoc PF09759.9 EPS28851.1 - 3.4e-06 27.0 0.2 0.79 9.8 0.0 4.1 3 1 0 4 4 4 2 Spinocerebellar ataxia type 10 protein domain CLASP_N PF12348.8 EPS28851.1 - 0.00022 20.9 1.9 0.42 10.1 0.0 3.6 3 0 0 3 3 3 1 CLASP N terminal Arm PF00514.23 EPS28851.1 - 0.00081 19.3 3.0 4.8 7.4 0.0 5.9 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EPS28851.1 - 0.001 19.5 4.8 27 5.4 0.0 6.3 7 0 0 7 7 7 0 HEAT-like repeat TIP120 PF08623.10 EPS28851.1 - 0.016 15.0 0.8 11 5.7 0.0 3.3 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) DNA_alkylation PF08713.11 EPS28851.1 - 0.14 11.8 0.1 1.8 8.3 0.0 2.6 2 1 1 3 3 3 0 DNA alkylation repair enzyme RTP1_C1 PF10363.9 EPS28851.1 - 0.34 11.1 1.9 2.5 8.3 0.0 3.1 3 1 2 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF1077 PF06417.12 EPS28852.1 - 1.9e-51 173.0 2.4 2.4e-51 172.7 2.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Rubella_Capsid PF05750.11 EPS28852.1 - 1 8.9 7.5 1.4 8.5 7.5 1.1 1 0 0 1 1 1 0 Rubella capsid protein MFS_1 PF07690.16 EPS28853.1 - 7e-50 169.9 22.1 7e-50 169.9 22.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS28853.1 - 3.8e-14 52.4 10.7 1.9e-13 50.1 1.8 2.7 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.7 EPS28853.1 - 0.00017 20.6 0.5 0.00017 20.6 0.5 2.1 3 0 0 3 3 3 1 MFS_1 like family MFS_5 PF05631.14 EPS28853.1 - 0.0023 16.9 0.8 0.0023 16.9 0.8 1.9 2 0 0 2 2 2 1 Sugar-tranasporters, 12 TM Osw5 PF17062.5 EPS28853.1 - 0.0064 16.6 0.4 0.058 13.5 0.0 2.7 3 0 0 3 3 3 1 Outer spore wall 5 OATP PF03137.20 EPS28853.1 - 0.1 10.8 3.9 0.55 8.5 1.4 2.4 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family UPF0542 PF15086.6 EPS28853.1 - 0.15 12.0 0.0 0.39 10.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 CPP1-like PF11833.8 EPS28853.1 - 2.2 7.9 4.9 6.9 6.3 4.9 1.8 1 0 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Aminotran_5 PF00266.19 EPS28854.1 - 4.2e-13 49.0 0.0 6.3e-13 48.4 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EPS28854.1 - 0.012 14.2 0.0 0.016 13.8 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EPS28854.1 - 0.025 13.9 0.1 0.042 13.2 0.1 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family OKR_DC_1 PF01276.20 EPS28854.1 - 0.092 11.5 0.3 0.2 10.3 0.3 1.5 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Fe-S_biosyn PF01521.20 EPS28855.1 - 3.2e-10 40.2 0.0 3.2e-09 36.9 0.0 2.2 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF4380 PF14315.6 EPS28856.1 - 0.18 10.7 0.1 0.36 9.7 0.1 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4380) Paf67 PF10255.9 EPS28857.1 - 2.4e-160 534.0 0.0 2.8e-160 533.7 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.17 EPS28857.1 - 0.027 14.5 0.0 0.16 12.2 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TRAPPC-Trs85 PF12739.7 EPS28857.1 - 0.11 11.5 0.2 0.15 11.0 0.2 1.2 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit HNH_2 PF13391.6 EPS28858.1 - 6.2e-07 29.5 0.0 1.9e-06 27.9 0.0 2.0 1 0 0 1 1 1 1 HNH endonuclease Aminotran_4 PF01063.19 EPS28859.1 - 1.2e-23 84.2 0.0 2e-23 83.5 0.0 1.4 1 0 0 1 1 1 1 Amino-transferase class IV AAR2 PF05282.11 EPS28860.1 - 3.8e-100 335.7 0.0 4.5e-100 335.5 0.0 1.0 1 0 0 1 1 1 1 AAR2 protein DUF577 PF04510.12 EPS28860.1 - 0.027 14.4 0.9 0.14 12.1 0.0 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF577) Cryptochrome_C PF12546.8 EPS28860.1 - 0.11 13.1 0.0 0.23 12.1 0.0 1.5 1 0 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal Ribosomal_S11 PF00411.19 EPS28861.1 - 2.9e-46 156.4 1.4 3.8e-46 156.0 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 EPS28861.1 - 0.089 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) PDH PF02153.17 EPS28862.1 - 1.1e-14 54.0 0.0 1.5e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.15 EPS28862.1 - 2.1e-06 28.0 0.0 6.3e-06 26.5 0.0 1.8 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EPS28862.1 - 4.3e-06 27.2 0.0 1.2e-05 25.8 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 EPS28862.1 - 0.00021 20.7 0.0 0.00035 20.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 EPS28862.1 - 0.0016 18.1 0.0 0.004 16.8 0.0 1.8 2 1 0 2 2 2 1 Ketopantoate reductase PanE/ApbA ScsC_N PF18312.1 EPS28862.1 - 0.0035 17.1 0.2 0.0091 15.8 0.2 1.7 1 0 0 1 1 1 1 Copper resistance protein ScsC N-terminal domain 3HCDH_N PF02737.18 EPS28862.1 - 0.0065 16.4 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EPS28862.1 - 0.092 12.8 0.0 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ERAP1_C PF11838.8 EPS28862.1 - 0.094 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 ERAP1-like C-terminal domain TrkA_N PF02254.18 EPS28862.1 - 0.18 12.1 0.0 0.36 11.1 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain RICTOR_N PF14664.6 EPS28863.1 - 1.6e-129 432.2 0.1 3.5e-129 431.1 0.1 1.6 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RasGEF_N_2 PF14663.6 EPS28863.1 - 8.6e-39 132.3 0.0 1.3e-35 122.0 0.0 3.4 3 0 0 3 3 3 2 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_M PF14666.6 EPS28863.1 - 1e-37 128.0 3.2 2.1e-34 117.4 0.4 4.5 5 0 0 5 5 5 2 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V PF14668.6 EPS28863.1 - 3.2e-26 91.4 3.3 1.6e-25 89.1 0.3 3.7 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.16 EPS28863.1 - 1.5e-15 57.0 7.6 3.8e-15 55.8 7.6 1.7 1 0 0 1 1 1 1 Hr1 repeat Uds1 PF15456.6 EPS28863.1 - 0.11 12.7 4.1 0.25 11.5 4.1 1.6 1 0 0 1 1 1 0 Up-regulated During Septation DLP_helical PF18709.1 EPS28863.1 - 0.74 9.0 2.4 1.3 8.1 2.4 1.3 1 0 0 1 1 1 0 Dynamin-like helical domain LON_substr_bdg PF02190.16 EPS28864.1 - 1e-27 97.4 0.0 1.5e-27 96.9 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 EPS28864.1 - 2e-12 46.7 18.6 2.1e-11 43.4 10.0 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EPS28864.1 - 2.5e-10 40.1 15.8 1.8e-09 37.3 6.1 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPS28864.1 - 1e-09 38.2 22.0 1.7e-07 31.2 4.8 3.3 3 0 0 3 3 3 2 RING-type zinc-finger zf-RING_5 PF14634.6 EPS28864.1 - 2e-09 37.3 17.0 3.3e-06 26.9 7.3 2.5 2 0 0 2 2 2 2 zinc-RING finger domain zf-RING_2 PF13639.6 EPS28864.1 - 4.5e-09 36.5 18.5 1.5e-07 31.6 9.0 2.7 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4 PF00097.25 EPS28864.1 - 8.2e-09 35.2 16.7 1.8e-07 30.9 8.8 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EPS28864.1 - 2.5e-08 33.9 19.9 1.7e-05 24.9 7.9 2.8 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EPS28864.1 - 3.8e-06 26.6 16.8 3.8e-05 23.5 7.1 2.5 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EPS28864.1 - 0.00029 20.6 7.6 0.00087 19.0 3.6 2.7 2 1 1 3 3 3 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 EPS28864.1 - 0.0015 18.8 4.0 0.0041 17.4 4.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-P11 PF03854.14 EPS28864.1 - 0.0022 17.6 3.8 0.0022 17.6 3.8 2.9 4 0 0 4 4 4 1 P-11 zinc finger U-box PF04564.15 EPS28864.1 - 0.0082 16.3 0.0 0.029 14.5 0.0 1.9 1 0 0 1 1 1 1 U-box domain zf-RING_10 PF16685.5 EPS28864.1 - 0.011 15.9 7.3 0.011 15.9 7.3 2.6 2 0 0 2 2 2 0 zinc RING finger of MSL2 Ribosomal_L40e PF01020.17 EPS28864.1 - 3.3 7.7 5.0 14 5.7 1.6 2.6 2 0 0 2 2 2 0 Ribosomal L40e family GPCR_chapero_1 PF11904.8 EPS28865.1 - 0.044 13.2 0.0 0.15 11.5 0.0 1.7 1 1 0 2 2 2 0 GPCR-chaperone Metallophos PF00149.28 EPS28866.1 - 3.1e-09 37.6 0.0 5e-09 37.0 0.0 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EPS28866.1 - 4.9e-08 33.4 0.3 3.6e-07 30.5 0.4 2.3 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain FBPase_2 PF06874.11 EPS28866.1 - 0.012 14.0 0.1 0.017 13.4 0.1 1.2 1 0 0 1 1 1 0 Firmicute fructose-1,6-bisphosphatase Metallophos_3 PF14582.6 EPS28866.1 - 0.054 12.8 0.1 0.097 12.0 0.1 1.3 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily Rad9 PF04139.13 EPS28867.1 - 1.2e-51 175.6 0.9 1.5e-51 175.2 0.9 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.16 EPS28867.1 - 0.0003 20.0 0.7 0.0049 16.0 0.7 2.6 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 RCC1 PF00415.18 EPS28868.1 - 7.7e-30 103.3 18.3 3.7e-09 37.0 0.0 7.2 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EPS28868.1 - 4.2e-19 67.8 19.4 6.5e-07 29.0 0.1 5.7 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Abhydrolase_1 PF00561.20 EPS28869.1 - 3.5e-16 59.6 0.1 1.2e-14 54.6 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 EPS28869.1 - 7.8e-14 51.6 0.1 5.9e-13 48.8 0.0 2.4 2 0 0 2 2 2 1 TAP-like protein Sugar_tr PF00083.24 EPS28870.1 - 1.2e-23 83.7 21.2 1.8e-14 53.5 4.8 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter Cation_ATPase_C PF00689.21 EPS28870.1 - 3.5 7.3 11.9 1.4 8.6 2.4 2.6 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus SUR7 PF06687.12 EPS28873.1 - 1.9e-17 63.6 0.7 2.3e-17 63.4 0.7 1.0 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 EPS28873.1 - 0.43 10.5 6.9 0.8 9.6 6.9 1.4 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 Mannitol_dh_C PF08125.13 EPS28875.1 - 7.3e-44 150.1 0.1 1.6e-43 149.0 0.0 1.6 2 0 0 2 2 2 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.23 EPS28875.1 - 1.1e-19 71.1 0.9 1.7e-19 70.4 0.2 1.7 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain 3HCDH_N PF02737.18 EPS28875.1 - 0.00036 20.5 0.2 0.00078 19.4 0.2 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EPS28875.1 - 0.0061 16.1 0.4 0.012 15.1 0.4 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_2 PF07992.14 EPS28875.1 - 0.036 13.3 0.5 0.036 13.3 0.5 1.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EPS28875.1 - 0.06 13.6 1.9 3.9 7.8 0.1 3.8 3 2 1 4 4 4 0 TrkA-N domain F420_oxidored PF03807.17 EPS28875.1 - 0.12 13.0 0.2 1 10.0 0.2 2.4 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF1993 PF09351.10 EPS28877.1 - 3.5e-41 141.0 0.8 4e-41 140.8 0.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) Med29 PF11568.8 EPS28877.1 - 0.14 12.4 0.4 0.22 11.7 0.4 1.4 1 1 0 1 1 1 0 Mediator complex subunit 29 PHAT PF09246.10 EPS28877.1 - 0.14 12.0 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 PHAT ECH_1 PF00378.20 EPS28878.1 - 1.5e-52 178.4 0.0 2.9e-44 151.3 0.0 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EPS28878.1 - 1.3e-23 84.0 0.1 2.4e-21 76.6 0.0 2.3 2 1 0 2 2 2 2 Enoyl-CoA hydratase/isomerase Myb_DNA-binding PF00249.31 EPS28879.1 - 8.4e-10 38.7 0.0 3.1e-09 36.9 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 EPS28879.1 - 4e-09 36.1 5.9 6.9e-09 35.4 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.17 EPS28879.1 - 6.4e-09 36.0 0.0 2.7e-08 34.0 0.0 2.0 2 0 0 2 2 2 1 SWIRM domain Vasohibin PF14822.6 EPS28879.1 - 0.1 11.8 0.1 0.19 10.9 0.1 1.4 1 0 0 1 1 1 0 Vasohibin Pkinase PF00069.25 EPS28880.1 - 6.5e-71 238.8 0.0 8.4e-71 238.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS28880.1 - 3.2e-33 115.1 0.0 4.4e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EPS28880.1 - 5.6e-09 36.6 1.7 7.5e-09 36.2 0.2 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EPS28880.1 - 7.9e-07 28.3 0.0 1.3e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EPS28880.1 - 0.01 15.2 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Coatomer_WDAD PF04053.14 EPS28881.1 - 2.1e-169 564.3 0.0 1e-168 562.0 0.0 1.9 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 EPS28881.1 - 9.2e-37 124.4 9.6 1.3e-06 29.0 0.0 8.1 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS28881.1 - 1.2e-06 28.7 0.0 2.8 8.3 0.0 5.8 4 2 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EPS28881.1 - 3.1e-05 22.8 2.1 0.12 11.0 0.0 3.7 2 1 2 4 4 4 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 EPS28881.1 - 0.0064 16.5 0.0 17 5.5 0.0 4.2 1 1 3 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Astro_capsid_p PF12226.8 EPS28881.1 - 9.8 5.2 8.4 14 4.7 8.4 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein ETC_C1_NDUFA5 PF04716.14 EPS28882.1 - 5.2e-29 99.8 2.2 1.3e-26 92.2 0.1 2.5 2 0 0 2 2 2 2 ETC complex I subunit conserved region Ku_PK_bind PF08785.11 EPS28882.1 - 0.0055 16.9 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Ku C terminal domain like Thioredoxin PF00085.20 EPS28883.1 - 7.3e-43 144.8 0.0 5.2e-25 87.4 0.0 4.3 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 EPS28883.1 - 3e-10 40.3 0.0 0.00011 22.1 0.0 4.6 3 1 2 5 5 5 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 EPS28883.1 - 3.2e-07 30.8 0.3 0.059 13.8 0.0 3.9 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EPS28883.1 - 0.00047 20.4 0.0 1.8 8.9 0.0 4.2 3 2 1 4 4 4 1 Thioredoxin-like HyaE PF07449.11 EPS28883.1 - 0.0007 19.5 0.0 0.67 9.9 0.0 2.9 3 0 0 3 3 3 2 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.21 EPS28883.1 - 0.005 16.7 0.8 0.14 12.0 0.0 2.9 3 0 0 3 3 3 1 AhpC/TSA family OST3_OST6 PF04756.13 EPS28883.1 - 0.066 12.6 0.0 11 5.3 0.0 2.5 2 0 0 2 2 2 0 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 EPS28883.1 - 0.18 12.0 1.0 0.86 9.8 0.1 2.6 4 0 0 4 4 4 0 Thioredoxin-like TraF PF13728.6 EPS28883.1 - 0.2 11.4 5.1 0.22 11.3 0.1 3.3 3 1 1 4 4 4 0 F plasmid transfer operon protein QCR10 PF09796.9 EPS28884.1 - 9.9e-23 80.0 0.1 1.4e-22 79.5 0.1 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) AA_permease_2 PF13520.6 EPS28885.1 - 7.8e-67 225.9 45.2 1e-66 225.5 45.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPS28885.1 - 2.5e-14 52.8 37.1 3.4e-14 52.3 37.1 1.2 1 0 0 1 1 1 1 Amino acid permease zf-H2C2_2 PF13465.6 EPS28888.1 - 5.4e-06 26.6 12.1 1.6e-05 25.1 1.4 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-Di19 PF05605.12 EPS28888.1 - 0.00019 21.6 4.8 0.00033 20.9 4.8 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 EPS28888.1 - 0.00024 21.7 15.0 0.017 15.9 5.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EPS28888.1 - 0.0019 18.4 4.8 0.079 13.3 1.2 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 EPS28888.1 - 0.03 14.8 14.5 0.12 12.9 7.1 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-met PF12874.7 EPS28888.1 - 0.74 10.3 5.0 4.2 7.9 0.8 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type PAD_porph PF04371.15 EPS28892.1 - 4.9e-94 315.2 0.0 6e-94 314.9 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase APH PF01636.23 EPS28894.1 - 1.2e-07 31.9 0.5 1.4e-07 31.7 0.5 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPS28894.1 - 0.00014 21.5 0.0 0.00017 21.3 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.20 EPS28894.1 - 0.14 11.4 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase Uricase PF01014.18 EPS28895.1 - 1.4e-77 258.3 3.2 2.9e-41 140.8 0.8 2.0 2 0 0 2 2 2 2 Uricase Mob_Pre PF01076.19 EPS28895.1 - 0.045 13.6 1.0 0.1 12.4 0.0 2.0 2 0 0 2 2 2 0 Plasmid recombination enzyme Ribosomal_L13 PF00572.18 EPS28896.1 - 2.5e-42 144.1 0.0 2.9e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Ribosomal_S9 PF00380.19 EPS28897.1 - 2.6e-33 115.1 0.7 3e-33 114.9 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DNA_pol_B PF00136.21 EPS28898.1 - 8.2e-118 394.0 0.3 1.2e-117 393.5 0.3 1.2 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 EPS28898.1 - 2.8e-69 232.6 0.7 5.3e-69 231.7 0.7 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 EPS28898.1 - 4.9e-42 144.3 0.0 9.1e-42 143.4 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 EPS28898.1 - 1.2e-24 86.2 11.9 1e-23 83.2 6.1 3.1 2 0 0 2 2 2 2 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 EPS28898.1 - 0.0098 14.8 0.0 0.021 13.7 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral MFS_1 PF07690.16 EPS28899.1 - 3.4e-41 141.3 40.7 1.7e-31 109.5 38.9 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EPS28899.1 - 0.00035 19.5 26.5 0.0023 16.9 3.8 2.6 2 1 0 2 2 2 2 MFS_1 like family OATP PF03137.20 EPS28899.1 - 0.0012 17.3 1.4 0.0012 17.3 1.4 4.0 2 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family ApbA PF02558.16 EPS28900.1 - 2.6e-26 92.1 0.0 3.5e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 EPS28900.1 - 1.2e-24 86.9 0.0 1.9e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Sacchrp_dh_NADP PF03435.18 EPS28900.1 - 0.0011 19.2 0.1 0.0021 18.3 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Phos_pyr_kin PF08543.12 EPS28901.1 - 5.7e-81 271.5 0.6 7.4e-81 271.1 0.6 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 EPS28901.1 - 4.1e-52 177.1 0.1 7e-52 176.3 0.1 1.4 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Carb_kinase PF01256.17 EPS28901.1 - 2e-05 24.2 1.6 4.3e-05 23.1 0.3 1.9 2 0 0 2 2 2 1 Carbohydrate kinase PfkB PF00294.24 EPS28901.1 - 4.4e-05 22.9 0.2 0.0013 18.2 0.2 2.2 1 1 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.15 EPS28901.1 - 0.0003 20.3 0.6 0.0089 15.4 0.1 2.2 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family DEAD PF00270.29 EPS28902.1 - 5.3e-49 166.3 0.0 4.5e-48 163.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPS28902.1 - 2.7e-30 105.0 0.1 1.3e-29 102.7 0.1 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPS28902.1 - 0.0027 17.7 0.0 0.014 15.4 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EPS28902.1 - 0.0062 15.8 0.2 0.0088 15.3 0.2 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase AAA_19 PF13245.6 EPS28902.1 - 0.017 15.5 0.0 1.7 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF5335 PF17269.2 EPS28902.1 - 0.05 13.5 0.2 0.09 12.6 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5335) UTP25 PF06862.12 EPS28902.1 - 0.077 11.8 1.9 1.9 7.2 0.0 2.4 3 0 0 3 3 3 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DUF2443 PF10398.9 EPS28902.1 - 0.18 11.8 0.3 0.46 10.6 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) Lipase_GDSL PF00657.22 EPS28903.1 - 0.00033 20.7 0.0 0.00044 20.3 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase zf-C2H2 PF00096.26 EPS28906.1 - 0.21 12.1 0.2 0.39 11.3 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type PPR_2 PF13041.6 EPS28908.1 - 5.5e-20 71.3 0.0 2.2e-15 56.6 0.0 2.9 2 0 0 2 2 2 2 PPR repeat family PPR_3 PF13812.6 EPS28908.1 - 2.1e-09 37.3 0.0 0.00014 21.9 0.0 2.6 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR PF01535.20 EPS28908.1 - 1.2e-05 25.2 0.0 0.0018 18.4 0.0 3.7 3 0 0 3 3 3 1 PPR repeat PPR_long PF17177.4 EPS28908.1 - 0.00028 20.3 0.0 0.00065 19.1 0.0 1.6 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP TAF1_subA PF14929.6 EPS28908.1 - 0.11 11.9 0.4 0.18 11.2 0.4 1.2 1 0 0 1 1 1 0 TAF RNA Polymerase I subunit A TPR_14 PF13428.6 EPS28908.1 - 3.6 8.7 5.1 5.4 8.1 0.4 3.4 2 1 1 3 3 3 0 Tetratricopeptide repeat Yip1 PF04893.17 EPS28909.1 - 9.4e-12 45.0 17.4 1.6e-11 44.3 17.4 1.4 1 1 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 EPS28909.1 - 0.062 13.1 5.4 0.096 12.5 5.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) DUF2070 PF09843.9 EPS28909.1 - 8.3 4.6 10.8 10 4.3 10.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Ran_BP1 PF00638.18 EPS28910.1 - 7.8e-18 64.9 0.5 1.4e-17 64.1 0.0 1.6 2 0 0 2 2 2 1 RanBP1 domain Nucleo_P87 PF07267.11 EPS28910.1 - 0.11 11.4 3.4 0.2 10.5 3.4 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SOBP PF15279.6 EPS28910.1 - 3.2 8.3 8.2 4.8 7.7 8.2 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein CCSAP PF15748.5 EPS28910.1 - 3.2 7.9 19.7 5.7 7.0 19.7 1.5 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Methyltransf_25 PF13649.6 EPS28911.1 - 7.9e-13 48.9 0.0 1.9e-12 47.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS28911.1 - 5.9e-10 39.7 0.0 1.6e-09 38.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPS28911.1 - 5.3e-09 36.1 0.0 7.5e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPS28911.1 - 7.3e-09 35.6 0.0 1e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPS28911.1 - 3e-08 34.3 0.0 6.9e-08 33.1 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.14 EPS28911.1 - 7.3e-05 22.4 0.0 0.0001 21.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 EPS28911.1 - 0.0069 15.9 0.0 0.024 14.1 0.0 1.7 1 1 0 2 2 2 1 Putative methyltransferase Methyltransf_32 PF13679.6 EPS28911.1 - 0.015 15.3 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 EPS28911.1 - 0.015 15.4 0.0 0.03 14.4 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.19 EPS28911.1 - 0.02 14.6 0.0 0.043 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 EPS28911.1 - 0.025 13.9 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain CheR PF01739.18 EPS28911.1 - 0.049 13.1 0.0 0.65 9.4 0.0 2.1 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain DEAD PF00270.29 EPS28912.1 - 1.2e-26 93.5 0.0 2.2e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 EPS28912.1 - 1.5e-17 64.1 0.3 5.3e-17 62.3 0.3 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 EPS28912.1 - 2.5e-12 47.1 0.0 6.2e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPS28912.1 - 4.8e-05 23.4 0.0 8.9e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 EPS28912.1 - 0.00053 20.3 0.0 0.0011 19.3 0.0 1.5 1 0 0 1 1 1 1 DNA replication factor CDT1 like ACD PF16671.5 EPS28913.1 - 0.1 10.9 0.0 0.15 10.4 0.0 1.2 1 0 0 1 1 1 0 Actin cross-linking domain DUF4744 PF15918.5 EPS28913.1 - 1.2 10.0 4.1 7.9 7.4 4.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4744) Fungal_trans_2 PF11951.8 EPS28914.1 - 4.3e-11 42.2 0.5 4.3e-11 42.2 0.5 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS28914.1 - 4.6e-07 29.8 9.5 7.6e-07 29.2 9.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_16 PF10294.9 EPS28915.1 - 9.3e-08 32.0 0.0 1.4e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase DUF993 PF06187.11 EPS28915.1 - 0.055 12.4 0.1 0.078 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF993) Formyl_trans_N PF00551.19 EPS28916.1 - 8.9e-40 136.3 0.1 1e-39 136.1 0.1 1.0 1 0 0 1 1 1 1 Formyl transferase zf-RING_2 PF13639.6 EPS28917.1 - 1.7e-13 50.6 5.2 2.7e-13 50.0 5.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EPS28917.1 - 6.5e-10 39.2 3.9 1.2e-09 38.2 3.9 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EPS28917.1 - 6.3e-09 35.5 4.9 1.1e-08 34.8 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EPS28917.1 - 3.5e-08 33.0 2.8 6.6e-08 32.2 2.8 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 EPS28917.1 - 1.5e-07 31.1 4.8 2.3e-07 30.5 4.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EPS28917.1 - 9.1e-06 25.4 3.2 1.5e-05 24.8 3.2 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EPS28917.1 - 1.5e-05 25.0 0.6 3.2e-05 23.9 0.6 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EPS28917.1 - 4.4e-05 23.0 3.5 7e-05 22.4 3.5 1.2 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 EPS28917.1 - 4.5e-05 23.3 3.3 6.8e-05 22.7 3.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EPS28917.1 - 0.00033 20.5 2.5 0.00054 19.8 2.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPS28917.1 - 0.00041 20.3 3.9 0.00084 19.3 3.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger RINGv PF12906.7 EPS28917.1 - 0.0045 17.1 5.7 0.0071 16.4 5.7 1.3 1 0 0 1 1 1 1 RING-variant domain zf-Nse PF11789.8 EPS28917.1 - 0.021 14.7 1.9 0.042 13.7 1.9 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.11 EPS28917.1 - 0.052 13.9 3.5 0.088 13.1 3.5 1.4 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_5 PF17121.5 EPS28917.1 - 0.055 13.4 1.2 0.1 12.5 1.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 EPS28917.1 - 0.062 13.5 3.5 0.11 12.7 3.5 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-C3H2C3 PF17122.5 EPS28917.1 - 0.095 12.8 1.7 0.19 11.8 1.7 1.5 1 0 0 1 1 1 0 Zinc-finger zf-RING_4 PF14570.6 EPS28917.1 - 0.1 12.4 4.1 0.16 11.7 4.1 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_9 PF13901.6 EPS28917.1 - 1.1 9.2 3.3 1.7 8.5 3.3 1.2 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon PHD PF00628.29 EPS28917.1 - 3.2 7.7 4.6 5.3 7.0 4.6 1.4 1 0 0 1 1 1 0 PHD-finger RNA_pol_I_TF PF04090.12 EPS28918.1 - 4.4e-12 45.9 0.0 1.2e-10 41.2 0.0 2.3 1 1 0 1 1 1 1 RNA polymerase I specific initiation factor TPR_6 PF13174.6 EPS28918.1 - 0.36 11.5 2.1 1.2 9.9 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat ECM11 PF15463.6 EPS28919.1 - 1e-40 139.4 0.0 4.1e-40 137.4 0.0 2.1 1 0 0 1 1 1 1 Extracellular mutant protein 11 VPS9 PF02204.18 EPS28920.1 - 6.9e-28 96.9 0.1 1.6e-27 95.8 0.1 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain RED_N PF07808.13 EPS28922.1 - 7.9e-07 28.9 2.4 3e-06 27.0 2.4 2.0 1 1 0 1 1 1 1 RED-like protein N-terminal region GvpG PF05120.12 EPS28922.1 - 0.11 12.5 3.4 0.11 12.5 1.1 2.2 2 0 0 2 2 2 0 Gas vesicle protein G zf-UBR PF02207.20 EPS28923.1 - 6.9e-19 67.8 15.0 1.9e-18 66.4 15.0 1.8 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 EPS28923.1 - 0.00099 18.8 0.0 0.0023 17.7 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_5 PF14634.6 EPS28923.1 - 0.011 15.7 0.7 0.011 15.7 0.7 3.9 3 1 1 4 4 4 0 zinc-RING finger domain SDA1 PF05285.12 EPS28923.1 - 0.99 8.8 7.9 1.9 7.9 7.9 1.4 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 EPS28923.1 - 2.4 7.4 8.2 5.4 6.3 8.2 1.5 1 0 0 1 1 1 0 BUD22 YL1 PF05764.13 EPS28923.1 - 2.9 8.0 12.5 0.2 11.8 6.6 1.9 2 0 0 2 2 2 0 YL1 nuclear protein Nop14 PF04147.12 EPS28923.1 - 3.9 5.6 9.9 6.6 4.8 9.9 1.2 1 0 0 1 1 1 0 Nop14-like family UCR_UQCRX_QCR9 PF05365.12 EPS28924.1 - 1.2e-27 95.5 1.7 1.4e-27 95.4 1.7 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Mago-bind PF09282.10 EPS28925.1 - 1.7e-13 50.1 6.5 3.1e-13 49.3 6.5 1.4 1 0 0 1 1 1 1 Mago binding eIF-3c_N PF05470.12 EPS28925.1 - 0.58 8.4 5.6 0.71 8.1 5.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Presenilin PF01080.17 EPS28925.1 - 9.3 4.9 6.4 11 4.6 6.4 1.1 1 0 0 1 1 1 0 Presenilin Amino_oxidase PF01593.24 EPS28926.1 - 1.1e-22 80.9 0.0 1.7e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EPS28926.1 - 1.8e-13 50.5 0.0 5.6e-13 48.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EPS28926.1 - 5e-07 29.6 0.1 1.1e-06 28.5 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase MCRA PF06100.11 EPS28926.1 - 0.0027 16.6 0.0 0.0042 15.9 0.0 1.2 1 0 0 1 1 1 1 MCRA family NAD_binding_9 PF13454.6 EPS28926.1 - 0.0085 16.1 0.1 0.033 14.2 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EPS28926.1 - 0.051 12.8 0.0 0.31 10.2 0.0 2.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EPS28926.1 - 0.059 12.1 0.0 0.17 10.6 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein zf-CCCH_2 PF14608.6 EPS28927.1 - 3.4e-15 55.9 60.2 9.3e-06 25.9 13.8 5.4 5 0 0 5 5 5 5 RNA-binding, Nab2-type zinc finger Nab2 PF11517.8 EPS28927.1 - 0.0046 17.2 0.0 0.0083 16.4 0.0 1.3 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) PAM2 PF07145.15 EPS28927.1 - 0.014 15.1 0.3 0.063 13.0 0.3 2.3 1 0 0 1 1 1 0 Ataxin-2 C-terminal region TRAM_LAG1_CLN8 PF03798.16 EPS28928.1 - 1.7e-42 145.4 19.5 1.7e-42 145.4 19.5 1.6 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 EPS28928.1 - 3.7e-18 64.9 1.1 9.1e-18 63.7 0.0 2.3 2 0 0 2 2 2 1 TRAM1-like protein PMP22_Claudin PF00822.20 EPS28929.1 - 2.4 8.0 11.4 0.089 12.7 1.2 3.0 4 0 0 4 4 4 0 PMP-22/EMP/MP20/Claudin family 4F5 PF04419.14 EPS28930.1 - 1.1e-11 45.3 9.8 1.1e-11 45.3 9.8 2.3 2 1 0 2 2 2 1 4F5 protein family PPTA PF01239.22 EPS28931.1 - 0.0065 16.2 5.7 0.61 9.9 0.1 3.0 3 0 0 3 3 3 2 Protein prenyltransferase alpha subunit repeat CHD5 PF04420.14 EPS28932.1 - 1.6e-61 206.8 3.6 2.5e-61 206.2 3.6 1.3 1 0 0 1 1 1 1 CHD5-like protein RRM_1 PF00076.22 EPS28934.1 - 1.7e-13 50.2 0.0 3.4e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EPS28934.1 - 0.0037 17.2 0.1 0.0079 16.2 0.1 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif YoeB_toxin PF06769.14 EPS28934.1 - 0.038 14.0 1.0 0.038 14.0 1.0 2.0 2 0 0 2 2 2 0 YoeB-like toxin of bacterial type II toxin-antitoxin system SMN PF06003.12 EPS28935.1 - 7e-08 32.0 10.6 1.1e-05 24.8 2.6 2.1 1 1 1 2 2 2 2 Survival motor neuron protein (SMN) DUF3729 PF12526.8 EPS28935.1 - 0.029 15.9 4.5 0.041 15.5 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3729) FAM176 PF14851.6 EPS28936.1 - 0.071 12.8 0.0 0.094 12.4 0.0 1.1 1 0 0 1 1 1 0 FAM176 family DUF3408 PF11888.8 EPS28936.1 - 0.093 12.9 2.9 0.12 12.5 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Rrn6 PF10214.9 EPS28936.1 - 0.85 8.0 5.7 1 7.8 5.7 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor AAA_33 PF13671.6 EPS28938.1 - 3.9e-19 69.2 0.0 4.6e-19 69.0 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EPS28938.1 - 2.6e-11 44.2 0.0 3.3e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EPS28938.1 - 1.2e-07 31.2 0.0 1.5e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.6 EPS28938.1 - 2.8e-06 27.8 0.0 3.6e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 EPS28938.1 - 0.00012 22.0 0.0 0.00019 21.3 0.0 1.3 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein KTI12 PF08433.10 EPS28938.1 - 0.00036 20.1 0.0 0.00049 19.6 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 APS_kinase PF01583.20 EPS28938.1 - 0.0014 18.6 0.0 0.0081 16.1 0.0 1.9 1 1 0 1 1 1 1 Adenylylsulphate kinase SKI PF01202.22 EPS28938.1 - 0.021 14.9 0.0 0.1 12.7 0.0 1.9 1 1 0 1 1 1 0 Shikimate kinase NB-ARC PF00931.22 EPS28938.1 - 0.031 13.5 0.0 0.042 13.0 0.0 1.3 1 1 0 1 1 1 0 NB-ARC domain BRCT PF00533.26 EPS28938.1 - 0.035 14.5 0.0 0.55 10.7 0.0 2.3 2 1 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain dNK PF01712.19 EPS28938.1 - 0.13 12.1 0.0 1.3 8.8 0.0 2.1 2 0 0 2 2 2 0 Deoxynucleoside kinase G-alpha PF00503.20 EPS28938.1 - 0.16 11.1 0.0 0.16 11.1 0.0 1.2 1 1 0 1 1 1 0 G-protein alpha subunit DUF3431 PF11913.8 EPS28939.1 - 6.1e-69 232.1 0.0 8.3e-69 231.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Thiolase_N PF00108.23 EPS28940.1 - 8.2e-18 64.7 0.1 2.3e-17 63.2 0.0 1.8 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EPS28940.1 - 5.5e-12 45.4 0.6 1.7e-10 40.6 0.0 2.5 1 1 1 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.10 EPS28940.1 - 4.3e-07 29.7 0.2 4.8e-05 23.1 0.1 2.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.26 EPS28940.1 - 0.0014 18.2 0.4 0.0031 17.1 0.4 1.5 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.11 EPS28940.1 - 0.014 14.1 0.1 0.031 13.0 0.1 1.5 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) Peptidase_S49 PF01343.18 EPS28940.1 - 0.016 15.2 0.1 0.22 11.5 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 Mito_carr PF00153.27 EPS28941.1 - 2.2e-42 142.9 4.8 1.5e-16 60.0 0.1 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF3337 PF11816.8 EPS28942.1 - 7e-36 123.7 0.0 7.4e-34 117.1 0.0 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF3337) Ank_2 PF12796.7 EPS28944.1 - 1.8e-21 76.5 0.3 2.2e-07 31.3 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPS28944.1 - 1.2e-17 64.0 1.4 4.7e-06 27.0 0.1 4.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPS28944.1 - 3.7e-17 60.7 1.2 0.0075 16.7 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 EPS28944.1 - 2e-16 59.8 0.9 1.8e-08 34.5 0.0 4.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EPS28944.1 - 1.9e-13 50.2 3.8 0.00092 19.6 0.0 5.8 6 0 0 6 6 6 4 Ankyrin repeat BRO1 PF03097.18 EPS28946.1 - 1.2e-124 416.1 1.2 2.3e-124 415.1 0.0 2.1 3 0 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EPS28946.1 - 1e-84 284.4 13.4 2.3e-84 283.2 13.4 1.6 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV TRP PF06011.12 EPS28949.1 - 1.1e-110 370.3 30.7 1.4e-110 370.0 30.7 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EPS28949.1 - 4.9e-30 104.7 0.1 7.2e-30 104.2 0.1 1.3 1 0 0 1 1 1 1 ML-like domain Baculo_11_kDa PF06143.11 EPS28949.1 - 0.61 9.7 7.2 2.8 7.6 0.9 2.9 3 0 0 3 3 3 0 Baculovirus 11 kDa family F-box_4 PF15966.5 EPS28950.1 - 0.0017 18.2 0.0 0.0032 17.3 0.0 1.4 1 0 0 1 1 1 1 F-box F-box PF00646.33 EPS28950.1 - 0.034 14.0 0.1 0.034 14.0 0.1 1.9 2 0 0 2 2 2 0 F-box domain Metallophos PF00149.28 EPS28951.1 - 7.1e-36 124.6 0.3 9.6e-36 124.2 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EPS28951.1 - 2.4e-16 59.9 0.4 5.5e-16 58.7 0.2 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Zn_clus PF00172.18 EPS28952.1 - 8.5e-09 35.4 6.5 1.6e-08 34.5 6.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.22 EPS28953.1 - 8e-184 611.5 0.1 9.1e-184 611.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EPS28953.1 - 0.15 11.5 0.0 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Cu_amine_oxid PF01179.20 EPS28955.1 - 1.2e-153 511.9 0.0 1.4e-153 511.6 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 EPS28955.1 - 1.4e-19 70.3 0.0 3.3e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 EPS28955.1 - 6.4e-12 45.5 0.1 1.2e-11 44.7 0.1 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DUF4881 PF16222.5 EPS28955.1 - 0.098 12.5 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4881) RVT_3 PF13456.6 EPS28955.1 - 0.12 12.2 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 Reverse transcriptase-like VitD-bind_III PF09164.10 EPS28955.1 - 0.23 11.5 1.4 0.65 10.0 1.4 1.7 1 0 0 1 1 1 0 Vitamin D binding protein, domain III Zn_clus PF00172.18 EPS28957.1 - 1.4e-09 37.9 10.6 2.3e-09 37.2 10.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LysM PF01476.20 EPS28959.1 - 0.00015 21.7 0.0 0.00024 21.1 0.0 1.3 1 0 0 1 1 1 1 LysM domain Rer1 PF03248.13 EPS28960.1 - 1.8e-81 271.9 2.4 2.1e-81 271.7 2.4 1.0 1 0 0 1 1 1 1 Rer1 family ECH_1 PF00378.20 EPS28961.1 - 2.6e-76 256.3 0.0 2.9e-76 256.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EPS28961.1 - 4.9e-37 128.2 0.4 7.1e-34 117.8 0.3 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 EPS28961.1 - 0.097 12.6 0.4 1.2 9.1 0.1 2.1 2 0 0 2 2 2 0 Peptidase family S49 PAS_3 PF08447.12 EPS28962.1 - 5.5e-11 42.6 0.0 3.5e-08 33.6 0.0 2.3 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 EPS28962.1 - 8e-08 32.5 0.0 7.5e-05 22.9 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 EPS28962.1 - 1.4e-07 31.5 0.0 0.00061 19.8 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_11 PF14598.6 EPS28962.1 - 0.00067 19.8 0.0 0.0031 17.6 0.0 1.9 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 EPS28962.1 - 0.0037 17.5 0.0 0.21 11.8 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_12 PF18095.1 EPS28962.1 - 0.17 11.5 0.0 17 5.0 0.0 2.3 2 0 0 2 2 2 0 UPF0242 C-terminal PAS-like domain Sugar_tr PF00083.24 EPS28963.1 - 5.5e-88 295.8 17.6 6.5e-88 295.6 17.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS28963.1 - 8.1e-17 61.2 24.1 1.5e-13 50.4 18.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EPS28963.1 - 0.00095 18.1 6.1 0.00095 18.1 6.1 2.2 2 0 0 2 2 2 1 MFS_1 like family ATP_transf PF09830.9 EPS28964.1 - 9.5e-19 67.3 0.0 1.6e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase AKAP7_NLS PF10469.9 EPS28966.1 - 2.5e-15 56.9 0.0 5.9e-15 55.7 0.0 1.6 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Sec6 PF06046.13 EPS28967.1 - 9.3e-169 562.5 9.6 1.8e-168 561.5 9.6 1.4 1 0 0 1 1 1 1 Exocyst complex component Sec6 HEAT_2 PF13646.6 EPS28967.1 - 0.04 14.3 1.1 0.77 10.2 0.1 3.5 3 1 0 3 3 3 0 HEAT repeats Vps53_N PF04100.12 EPS28967.1 - 0.18 10.8 9.2 0.023 13.7 0.9 2.5 2 0 0 2 2 2 0 Vps53-like, N-terminal Ribosomal_L30 PF00327.20 EPS28968.1 - 1.6e-14 53.5 0.3 2.1e-14 53.2 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Pyridoxal_deC PF00282.19 EPS28969.1 - 2.4e-17 62.7 0.0 3.5e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EPS28969.1 - 2e-08 33.6 0.0 1.6e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EPS28969.1 - 3.1e-06 26.6 0.0 5.5e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EPS28969.1 - 0.00097 18.5 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EPS28969.1 - 0.046 12.2 0.0 0.07 11.7 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme HMGL-like PF00682.19 EPS28970.1 - 3.7e-80 269.3 0.3 5.1e-80 268.8 0.3 1.2 1 0 0 1 1 1 1 HMGL-like Endonuc-BglII PF09195.11 EPS28970.1 - 0.11 12.4 0.1 0.42 10.4 0.0 2.0 2 0 0 2 2 2 0 Restriction endonuclease BglII PTH2 PF01981.16 EPS28972.1 - 8.1e-41 139.0 0.1 1.1e-40 138.6 0.1 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 SART-1 PF03343.13 EPS28973.1 - 2.3e-192 640.9 66.5 2.7e-192 640.7 66.5 1.0 1 0 0 1 1 1 1 SART-1 family Aminotran_1_2 PF00155.21 EPS28974.1 - 9.9e-94 314.5 0.0 1.1e-93 314.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II ABC_tran PF00005.27 EPS28975.1 - 7.9e-50 168.9 0.0 9e-32 110.4 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EPS28975.1 - 2e-32 113.0 32.9 7.9e-24 84.8 9.4 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.6 EPS28975.1 - 1.8e-10 41.1 0.4 0.0016 18.3 0.0 4.2 2 2 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EPS28975.1 - 2e-06 27.4 1.7 0.00033 20.2 0.4 3.4 2 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_33 PF13671.6 EPS28975.1 - 2.1e-06 28.0 0.1 0.022 14.9 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EPS28975.1 - 6.3e-06 25.9 0.7 0.026 14.1 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 EPS28975.1 - 3.1e-05 24.3 0.0 0.3 11.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EPS28975.1 - 6.1e-05 23.6 0.0 0.097 13.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EPS28975.1 - 0.00019 21.1 2.0 0.54 10.0 0.2 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EPS28975.1 - 0.0022 17.9 0.5 0.43 10.5 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA PF00004.29 EPS28975.1 - 0.0055 17.1 0.0 0.35 11.3 0.0 3.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 EPS28975.1 - 0.0064 16.6 0.2 5.5 7.1 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase TsaE PF02367.17 EPS28975.1 - 0.01 15.8 0.7 0.1 12.6 0.1 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EPS28975.1 - 0.015 15.2 0.5 1.3 9.0 0.0 2.9 3 0 0 3 3 2 0 NACHT domain AAA_16 PF13191.6 EPS28975.1 - 0.022 15.1 0.0 3.4 8.0 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain Mg_chelatase PF01078.21 EPS28975.1 - 0.027 13.9 0.0 6.2 6.1 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EPS28975.1 - 0.029 14.8 0.0 6.3 7.3 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Rad17 PF03215.15 EPS28975.1 - 0.034 14.1 0.3 0.16 11.9 0.1 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_5 PF07728.14 EPS28975.1 - 0.069 13.2 2.0 3.6 7.6 0.2 2.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EPS28975.1 - 0.082 12.4 0.2 5.3 6.5 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 EPS28975.1 - 0.089 12.5 0.7 7.2 6.3 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_24 PF13479.6 EPS28975.1 - 0.093 12.4 0.3 6.4 6.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EPS28975.1 - 0.12 12.5 0.1 0.3 11.2 0.1 1.6 1 0 0 1 1 1 0 Helicase HerA, central domain PduV-EutP PF10662.9 EPS28975.1 - 0.14 11.9 0.6 1.6 8.5 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 EPS28975.1 - 0.2 12.2 3.8 12 6.3 0.3 2.4 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EPS28975.1 - 0.2 11.7 0.3 6.1 6.9 0.0 2.4 2 0 0 2 2 2 0 Dynamin family RuBisCO_large PF00016.20 EPS28976.1 - 0.012 14.8 4.3 8.2 5.5 0.1 3.6 1 1 6 7 7 7 0 Ribulose bisphosphate carboxylase large chain, catalytic domain CsgE PF10627.9 EPS28976.1 - 0.034 14.4 16.3 66 3.8 0.1 7.4 1 1 7 8 8 8 0 Curli assembly protein CsgE GTP_EFTU_D2 PF03144.25 EPS28976.1 - 0.14 12.5 0.0 51 4.4 0.0 3.4 2 1 1 4 4 4 0 Elongation factor Tu domain 2 DUF3328 PF11807.8 EPS28977.1 - 5.3e-42 144.1 3.4 6.8e-42 143.7 3.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.8 EPS28978.1 - 2.3e-42 145.3 0.1 3.2e-42 144.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) MFS_1 PF07690.16 EPS28979.1 - 9.8e-22 77.3 43.1 1.5e-17 63.5 20.5 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Carn_acyltransf PF00755.20 EPS28980.1 - 4.6e-116 388.8 0.0 1.1e-115 387.6 0.0 1.6 2 0 0 2 2 2 1 Choline/Carnitine o-acyltransferase ketoacyl-synt PF00109.26 EPS28980.1 - 1.1e-77 261.0 0.0 2.1e-77 260.1 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EPS28980.1 - 2.8e-52 178.2 0.8 5.9e-52 177.1 0.8 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 EPS28980.1 - 3.9e-52 176.8 0.0 1.2e-51 175.2 0.0 2.0 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 EPS28980.1 - 9.1e-48 163.0 0.0 1.6e-47 162.2 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 EPS28980.1 - 6.4e-38 129.4 0.2 2e-37 127.8 0.2 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 EPS28980.1 - 1.6e-17 64.8 0.0 3.9e-16 60.3 0.0 2.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EPS28980.1 - 1.4e-15 57.4 1.0 2.6e-14 53.3 0.0 3.5 4 0 0 4 4 4 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 EPS28980.1 - 2.4e-15 56.9 0.7 1.7e-14 54.2 0.7 2.5 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 EPS28980.1 - 1.4e-10 40.9 0.1 9.7e-10 38.2 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_12 PF08242.12 EPS28980.1 - 5.4e-10 39.9 0.0 1.9e-09 38.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPS28980.1 - 3.3e-07 30.2 0.0 9.4e-07 28.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPS28980.1 - 4.7e-07 30.4 0.0 2.1e-06 28.3 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EPS28980.1 - 5.8e-07 29.8 0.5 1.4e-06 28.5 0.5 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.6 EPS28980.1 - 1.3e-06 28.3 0.0 5.3e-06 26.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPS28980.1 - 1.4e-06 27.9 0.0 2.8e-05 23.6 0.0 2.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 EPS28980.1 - 2.3e-06 28.2 0.0 8.7e-06 26.3 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain adh_short_C2 PF13561.6 EPS28980.1 - 3.6e-06 26.7 0.0 7.6e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EPS28980.1 - 1.3e-05 24.8 0.0 2.6e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Thiolase_N PF00108.23 EPS28980.1 - 0.00078 18.9 0.5 0.0017 17.8 0.5 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain SAT PF16073.5 EPS28980.1 - 0.0023 17.7 0.7 0.0057 16.4 0.7 1.7 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis 3Beta_HSD PF01073.19 EPS28980.1 - 0.0059 15.6 0.0 0.013 14.5 0.0 1.6 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_16 PF10294.9 EPS28980.1 - 0.019 14.7 0.0 0.042 13.6 0.0 1.5 1 0 0 1 1 1 0 Lysine methyltransferase NAD_binding_10 PF13460.6 EPS28980.1 - 0.049 13.5 1.1 0.16 11.9 0.1 2.5 3 0 0 3 3 2 0 NAD(P)H-binding F420_oxidored PF03807.17 EPS28980.1 - 0.18 12.4 0.3 10 6.8 0.0 3.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent RTA1 PF04479.13 EPS28981.1 - 1.5e-70 237.0 12.1 1.5e-70 237.0 12.1 1.4 2 0 0 2 2 2 1 RTA1 like protein DUF3007 PF11460.8 EPS28981.1 - 0.0074 16.5 0.3 0.44 10.8 0.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3007) DUF3169 PF11368.8 EPS28981.1 - 0.023 14.2 7.1 0.18 11.3 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) PRA1 PF03208.19 EPS28981.1 - 6.1 6.5 17.1 2.1 8.0 5.2 2.8 2 1 0 2 2 2 0 PRA1 family protein Sulfotransfer_4 PF17784.1 EPS28982.1 - 1.1e-56 192.0 0.0 1.3e-56 191.8 0.0 1.1 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EPS28982.1 - 4.6e-06 27.2 0.6 4.5e-05 23.9 0.0 2.3 1 1 0 2 2 2 1 Sulfotransferase family MFS_1 PF07690.16 EPS28983.1 - 8.5e-37 126.9 45.7 1.3e-36 126.3 45.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Transferase PF02458.15 EPS28984.1 - 6.8e-13 48.1 0.0 1.6e-12 46.8 0.0 1.5 1 1 0 1 1 1 1 Transferase family DUF155 PF02582.14 EPS28985.1 - 2.9e-53 180.6 0.0 4.4e-53 180.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF2561 PF10812.8 EPS28985.1 - 0.0031 17.6 0.1 0.0097 16.0 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2561) Pex14_N PF04695.13 EPS28985.1 - 3.9 8.1 11.5 11 6.6 3.1 2.6 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CDC45 PF02724.14 EPS28985.1 - 9.8 4.3 11.0 9.4 4.4 6.3 2.1 2 0 0 2 2 2 0 CDC45-like protein ELL PF10390.9 EPS28986.1 - 0.0027 17.3 0.1 0.0027 17.3 0.1 2.2 2 1 0 2 2 2 1 RNA polymerase II elongation factor ELL UPF0506 PF11703.8 EPS28988.1 - 1.1 9.7 25.9 3.9 7.9 11.7 2.8 2 1 0 2 2 2 0 UPF0506 zf-C2H2 PF00096.26 EPS28990.1 - 9.7e-19 66.7 27.1 3.6e-05 24.0 1.7 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EPS28990.1 - 3e-17 62.2 25.9 1.4e-06 28.4 1.5 5.4 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EPS28990.1 - 8.6e-10 38.6 24.6 0.0041 17.8 1.3 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EPS28990.1 - 1e-05 25.7 2.3 0.66 10.3 0.1 4.2 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EPS28990.1 - 0.001 19.4 14.2 0.018 15.4 0.2 3.9 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf_UBZ PF18439.1 EPS28990.1 - 0.016 14.8 1.9 1.1 8.9 0.2 2.8 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_aberr PF17017.5 EPS28990.1 - 0.017 15.3 0.7 2.9 8.0 0.1 2.2 2 0 0 2 2 2 0 Aberrant zinc-finger zf-C2H2_11 PF16622.5 EPS28990.1 - 0.017 14.8 9.9 0.02 14.7 0.8 3.4 3 0 0 3 3 3 0 zinc-finger C2H2-type DDE_Tnp_1_6 PF13751.6 EPS28990.1 - 0.027 14.7 2.1 0.028 14.6 0.4 1.9 2 0 0 2 2 2 0 Transposase DDE domain FOXP-CC PF16159.5 EPS28990.1 - 0.032 14.9 10.6 0.23 12.1 0.8 3.6 3 1 1 4 4 4 0 FOXP coiled-coil domain Yippee-Mis18 PF03226.14 EPS28990.1 - 0.28 11.4 1.5 18 5.6 0.1 2.3 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HNH PF01844.23 EPS28990.1 - 2.5 8.4 8.6 7.9 6.7 0.1 3.8 4 0 0 4 4 4 0 HNH endonuclease DUF2256 PF10013.9 EPS28990.1 - 3.6 7.8 8.7 23 5.2 0.0 3.6 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2256) C1_4 PF07975.12 EPS28990.1 - 4.7 7.5 6.4 2.7 8.3 0.2 2.8 1 1 2 3 3 3 0 TFIIH C1-like domain Zn-ribbon_8 PF09723.10 EPS28990.1 - 4.9 7.4 8.2 16 5.7 1.3 3.1 1 1 3 4 4 4 0 Zinc ribbon domain Fringe PF02434.16 EPS28991.1 - 4.3e-12 46.0 0.1 1.1e-11 44.7 0.1 1.6 1 1 0 1 1 1 1 Fringe-like DUF604 PF04646.12 EPS28991.1 - 2.9e-10 40.0 0.0 5.1e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF604 PhoLip_ATPase_C PF16212.5 EPS28992.1 - 1.3e-72 244.6 21.7 1.3e-72 244.6 21.7 2.4 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EPS28992.1 - 2.2e-23 81.7 4.1 1.1e-22 79.5 1.0 2.5 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EPS28992.1 - 3.1e-13 50.5 1.5 0.00011 22.5 0.1 3.5 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EPS28992.1 - 2.5e-11 43.5 0.2 5.9e-10 39.1 0.0 3.1 3 1 1 4 4 4 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EPS28992.1 - 3e-11 43.2 0.1 3e-11 43.2 0.1 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EPS28992.1 - 0.0011 18.7 0.2 0.0035 17.1 0.2 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Sec34 PF04136.15 EPS28992.1 - 0.12 12.3 0.1 0.3 11.0 0.1 1.6 1 0 0 1 1 1 0 Sec34-like family DPBB_1 PF03330.18 EPS28992.1 - 0.12 12.7 0.0 0.38 11.0 0.0 1.8 1 0 0 1 1 1 0 Lytic transglycolase HCV_NS5a_1b PF08301.13 EPS28992.1 - 0.13 12.8 0.5 0.39 11.3 0.1 1.9 2 0 0 2 2 2 0 Hepatitis C virus non-structural 5a domain 1b vWA-TerF-like PF10138.9 EPS28993.1 - 0.00016 21.9 0.0 0.00026 21.1 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus GFO_IDH_MocA PF01408.22 EPS28994.1 - 0.00041 21.2 0.0 0.0011 19.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold SRP_TPR_like PF17004.5 EPS28995.1 - 6.6e-21 74.5 1.8 2.4e-20 72.7 1.1 2.3 2 0 0 2 2 2 1 Putative TPR-like repeat SRP72 PF08492.12 EPS28995.1 - 1e-15 57.9 4.0 1e-15 57.9 4.0 2.6 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_19 PF14559.6 EPS28995.1 - 1.8e-08 34.7 29.2 0.034 14.7 0.6 7.7 5 3 3 8 8 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EPS28995.1 - 1.1e-05 25.6 14.1 0.0014 18.8 2.8 4.6 4 1 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EPS28995.1 - 0.0002 21.1 7.8 0.16 12.1 0.0 5.3 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EPS28995.1 - 0.03 15.1 30.4 2.3 9.3 0.1 9.0 7 3 5 12 12 10 0 Tetratricopeptide repeat PPR PF01535.20 EPS28995.1 - 0.037 14.3 0.0 51 4.4 0.0 4.1 4 0 0 4 4 4 0 PPR repeat TPR_4 PF07721.14 EPS28995.1 - 0.08 13.6 16.6 2.4 9.0 0.0 5.3 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EPS28995.1 - 0.15 12.2 21.3 3.9 7.8 0.0 7.2 8 0 0 8 8 7 0 Tetratricopeptide repeat Endonuclease_1 PF04231.13 EPS28995.1 - 0.16 11.6 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 Endonuclease I TPR_8 PF13181.6 EPS28995.1 - 0.18 12.1 7.6 14 6.2 0.0 5.7 7 0 0 7 7 5 0 Tetratricopeptide repeat ELYS PF13934.6 EPS28995.1 - 0.34 10.8 2.9 0.45 10.5 0.2 2.4 3 0 0 3 3 3 0 Nuclear pore complex assembly TPR_1 PF00515.28 EPS28995.1 - 0.65 9.9 10.7 22 5.0 0.2 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 EPS28995.1 - 2.9 8.5 4.8 67 4.2 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EPS28995.1 - 6.4 6.8 8.4 1.4e+02 2.6 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Aminotran_3 PF00202.21 EPS28997.1 - 5.4e-87 292.1 0.0 6.5e-87 291.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EPS28997.1 - 0.00071 18.9 0.0 0.0016 17.7 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class I and II Homeodomain PF00046.29 EPS28999.1 - 1.3e-19 69.8 2.5 2.6e-19 68.8 2.5 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EPS28999.1 - 0.0011 18.8 1.4 0.0094 15.8 0.6 2.4 2 0 0 2 2 2 1 Homeobox KN domain PGP_phosphatase PF09419.10 EPS29000.1 - 2.6e-60 202.8 0.0 3.1e-60 202.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 EPS29000.1 - 0.00016 21.7 0.0 0.0003 20.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like LSM PF01423.22 EPS29001.1 - 4.5e-15 55.1 0.3 6e-15 54.7 0.3 1.2 1 0 0 1 1 1 1 LSM domain Adaptin_binding PF10199.9 EPS29002.1 - 1.6e-17 64.2 2.0 1.6e-17 64.2 2.0 1.9 2 0 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 PTPLA PF04387.14 EPS29003.1 - 3.1e-58 196.1 4.9 4.6e-58 195.6 4.9 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Hpt PF01627.23 EPS29006.1 - 1.1e-09 38.4 0.0 2.3e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Hpt domain Trypan_PARP PF05887.11 EPS29006.1 - 0.21 11.6 14.6 0.31 11.0 14.6 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PilP PF04351.13 EPS29006.1 - 0.23 11.4 7.2 4.2 7.3 0.0 2.2 2 0 0 2 2 2 0 Pilus assembly protein, PilP MCU PF04678.13 EPS29008.1 - 1.5e-26 93.5 0.1 1.5e-26 93.5 0.1 1.8 2 0 0 2 2 2 1 Mitochondrial calcium uniporter dsrm PF00035.26 EPS29009.1 - 9.4e-05 23.0 0.0 0.00019 22.1 0.0 1.5 2 0 0 2 2 2 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 EPS29009.1 - 0.011 16.0 0.4 0.029 14.6 0.4 1.7 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 p450 PF00067.22 EPS29010.1 - 6.5e-65 219.7 0.0 8.5e-65 219.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.6 EPS29011.1 - 1.1e-05 25.3 0.0 2.6e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPS29011.1 - 4.8e-05 24.0 0.0 0.0002 22.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPS29011.1 - 0.00036 21.2 0.0 0.0011 19.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS29011.1 - 0.014 16.0 0.0 0.043 14.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Prenyltrans PF00432.21 EPS29012.1 - 4.2e-37 125.6 33.0 4e-12 45.7 1.3 6.4 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 EPS29012.1 - 0.0075 15.4 0.2 0.43 9.6 0.0 2.4 1 1 1 2 2 2 2 Squalene-hopene cyclase N-terminal domain DUF4807 PF16065.5 EPS29013.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4807) Zn_clus PF00172.18 EPS29014.1 - 0.0039 17.3 7.7 0.0073 16.4 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ubiquitin PF00240.23 EPS29015.1 - 4.1e-124 404.5 22.1 3.1e-33 113.4 0.6 4.5 4 1 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 EPS29015.1 - 6e-59 195.8 19.1 1.9e-15 56.5 0.7 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EPS29015.1 - 2.4e-21 76.0 9.9 0.00041 20.8 0.1 5.4 4 3 0 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 EPS29015.1 - 1.4e-16 60.2 2.7 0.025 14.5 0.0 4.2 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EPS29015.1 - 6.4e-13 48.9 6.2 0.021 15.2 0.1 4.1 3 1 1 4 4 4 3 Ubiquitin-like domain DUF2407 PF10302.9 EPS29015.1 - 2.2e-12 47.4 1.0 0.35 11.5 0.0 4.2 1 1 2 4 4 4 4 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EPS29015.1 - 8.3e-12 45.2 3.4 0.12 12.5 0.0 5.0 3 3 1 4 4 4 3 Ubiquitin-2 like Rad60 SUMO-like Sde2_N_Ubi PF13019.6 EPS29015.1 - 1.2e-08 35.0 2.9 0.49 10.2 0.0 4.5 2 1 3 5 5 5 3 Silencing defective 2 N-terminal ubiquitin domain Ubiquitin_4 PF18036.1 EPS29015.1 - 3.1e-06 27.1 21.6 14 5.8 0.2 7.3 7 1 1 8 8 7 0 Ubiquitin-like domain DUF3861 PF12977.7 EPS29015.1 - 4.3e-06 26.8 2.9 12 6.1 0.0 4.2 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) Methyltrans_RNA PF04452.14 EPS29015.1 - 5e-06 26.0 0.2 1.8 7.8 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase ACT_5 PF13710.6 EPS29015.1 - 1e-05 25.3 4.7 9.7 6.1 0.0 4.3 4 0 0 4 4 4 0 ACT domain Big_7 PF17957.1 EPS29015.1 - 3.4e-05 24.5 0.3 44 5.0 0.0 4.1 4 0 0 4 4 4 0 Bacterial Ig domain DUF2870 PF11069.8 EPS29015.1 - 0.00032 21.0 0.0 28 5.2 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) YcgR_2 PF12945.7 EPS29015.1 - 0.00059 19.9 5.8 26 5.1 0.1 4.3 4 0 0 4 4 4 0 Flagellar protein YcgR DUF493 PF04359.14 EPS29015.1 - 0.0025 18.3 0.1 1.3e+02 3.2 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF493) Raf1_HTH PF18579.1 EPS29015.1 - 0.0031 17.2 0.0 99 2.7 0.0 4.1 4 0 0 4 4 4 0 Rubisco accumulation factor 1 helix turn helix domain UDP-g_GGTase PF06427.11 EPS29015.1 - 0.0036 17.4 3.2 6.7 6.9 0.0 3.9 4 0 0 4 4 4 0 UDP-glucose:Glycoprotein Glucosyltransferase ACT_4 PF13291.6 EPS29015.1 - 0.0044 17.6 1.0 1.3e+02 3.2 0.0 4.2 4 0 0 4 4 4 0 ACT domain DUF969 PF06149.12 EPS29015.1 - 0.022 14.2 0.0 22 4.4 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF969) ProRS-C_2 PF09181.10 EPS29015.1 - 0.093 12.9 5.8 1e+02 3.2 0.1 4.1 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal Tash_PEST PF07708.11 EPS29015.1 - 0.12 12.5 27.2 6 7.2 1.4 4.3 4 0 0 4 4 4 0 Tash protein PEST motif HAMP_N3 PF18575.1 EPS29015.1 - 0.2 11.2 1.5 1.9e+02 1.7 0.0 3.9 4 0 0 4 4 4 0 HAMP N-terminal domain 3 Myosin_N PF02736.19 EPS29015.1 - 0.23 11.3 6.3 1e+02 2.8 0.0 5.1 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain Plexin_cytopl PF08337.12 EPS29015.1 - 0.65 8.6 15.0 13 4.3 0.2 4.7 4 2 0 5 5 5 0 Plexin cytoplasmic RasGAP domain PI3K_p85B PF02192.16 EPS29015.1 - 1.7 8.5 9.3 92 2.9 0.1 4.2 4 0 0 4 4 4 0 PI3-kinase family, p85-binding domain FlgD_ig PF13860.6 EPS29015.1 - 8.1 6.4 9.1 1.7e+02 2.1 0.1 4.2 4 0 0 4 4 4 0 FlgD Ig-like domain BRAP2 PF07576.12 EPS29016.1 - 9.6e-34 115.6 0.0 1.6e-33 114.9 0.0 1.3 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 EPS29016.1 - 1.8e-19 69.8 6.2 5.9e-19 68.2 6.2 1.9 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 EPS29016.1 - 5e-08 33.1 9.5 5e-08 33.1 9.5 2.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EPS29016.1 - 1.6e-05 24.7 9.7 1.6e-05 24.7 9.7 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) TolA_bind_tri PF16331.5 EPS29016.1 - 0.00029 20.8 6.9 0.00074 19.5 1.1 2.9 2 1 1 3 3 3 1 TolA binding protein trimerisation zf-RING_UBOX PF13445.6 EPS29016.1 - 0.00036 20.5 6.1 0.0028 17.7 6.6 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 EPS29016.1 - 0.00074 19.8 7.1 0.00074 19.8 7.1 1.9 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EPS29016.1 - 0.00098 18.9 5.6 0.00098 18.9 5.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EPS29016.1 - 0.0011 18.6 5.7 0.0011 18.6 5.7 2.7 2 0 0 2 2 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 EPS29016.1 - 0.0013 18.5 8.8 0.0013 18.5 8.8 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EPS29016.1 - 0.0024 17.8 7.9 0.0024 17.8 7.9 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 EPS29016.1 - 0.0026 17.6 3.1 0.0079 16.0 3.1 1.8 1 0 0 1 1 1 1 zf-RING of BARD1-type protein T3SSipB PF16535.5 EPS29016.1 - 0.013 15.9 3.4 0.024 15.1 3.4 1.4 1 0 0 1 1 1 0 Type III cell invasion protein SipB zf-ANAPC11 PF12861.7 EPS29016.1 - 0.018 15.1 5.6 0.046 13.8 5.6 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Lectin_N PF03954.14 EPS29016.1 - 0.072 12.8 1.3 0.16 11.7 1.3 1.6 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain GAS PF13851.6 EPS29016.1 - 0.072 12.4 7.1 0.11 11.8 7.1 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding CCDC92 PF14916.6 EPS29016.1 - 0.08 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain of unknown function Exonuc_VII_L PF02601.15 EPS29016.1 - 0.18 11.3 4.6 0.31 10.5 4.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3584 PF12128.8 EPS29016.1 - 0.22 9.0 8.8 0.29 8.6 8.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Occludin_ELL PF07303.13 EPS29016.1 - 0.24 12.1 0.9 0.66 10.7 0.9 1.7 1 0 0 1 1 1 0 Occludin homology domain Med21 PF11221.8 EPS29016.1 - 0.27 11.5 3.8 0.66 10.2 3.8 1.5 1 0 0 1 1 1 0 Subunit 21 of Mediator complex HALZ PF02183.18 EPS29016.1 - 0.33 11.2 4.6 0.9 9.8 0.8 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper Prok-RING_4 PF14447.6 EPS29016.1 - 0.57 10.1 20.7 0.098 12.5 9.8 3.3 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 DUF1455 PF07306.11 EPS29016.1 - 0.7 9.9 6.0 0.072 13.1 0.9 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF1455) HAP1_N PF04849.13 EPS29016.1 - 0.87 8.7 11.8 1.3 8.1 11.8 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Rootletin PF15035.6 EPS29016.1 - 1.1 9.2 11.1 1.9 8.4 10.6 1.5 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DivIC PF04977.15 EPS29016.1 - 1.8 8.4 3.6 2.2 8.1 0.0 2.4 2 1 0 2 2 2 0 Septum formation initiator FapA PF03961.13 EPS29016.1 - 2.1 6.9 4.3 3.1 6.3 4.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A ALS2CR11 PF15729.5 EPS29016.1 - 2.7 7.0 5.1 1.2 8.1 0.1 2.0 1 1 1 2 2 2 0 Amyotrophic lateral sclerosis 2 candidate 11 JIP_LZII PF16471.5 EPS29016.1 - 2.8 8.2 13.0 0.15 12.3 1.0 2.8 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II bZIP_1 PF00170.21 EPS29016.1 - 3 8.0 9.0 0.48 10.6 1.5 2.5 1 1 2 3 3 3 0 bZIP transcription factor DUF4407 PF14362.6 EPS29016.1 - 3 7.1 9.8 22 4.3 8.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) zf-RING_4 PF14570.6 EPS29016.1 - 3.2 7.6 6.7 7.5 6.4 6.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Uso1_p115_C PF04871.13 EPS29016.1 - 4.6 7.6 18.7 0.31 11.4 5.9 2.2 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region TPR_MLP1_2 PF07926.12 EPS29016.1 - 4.9 7.2 19.2 1.2e+02 2.7 17.7 2.3 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 EPS29016.1 - 5.4 5.8 14.7 11 4.8 14.5 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein SPATA24 PF15175.6 EPS29016.1 - 6.7 6.6 8.3 17 5.3 5.8 2.1 1 1 1 2 2 2 0 Spermatogenesis-associated protein 24 Methyltransf_23 PF13489.6 EPS29017.1 - 2.7e-14 53.3 0.0 3.9e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS29017.1 - 2.7e-12 47.2 0.0 7e-10 39.4 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPS29017.1 - 2e-10 41.3 0.0 1.8e-09 38.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPS29017.1 - 3.1e-10 40.6 0.0 0.00071 20.2 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 EPS29017.1 - 1.4e-07 31.4 0.0 0.0036 17.1 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Fungal_trans PF04082.18 EPS29018.1 - 6.3e-13 48.4 0.1 9.4e-13 47.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS29018.1 - 1.4e-08 34.7 11.6 1.4e-08 34.7 11.6 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_31 PF01055.26 EPS29020.1 - 3.1e-154 514.4 3.5 4.6e-154 513.8 3.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 EPS29020.1 - 2.2e-34 118.1 0.0 4.1e-34 117.2 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 EPS29020.1 - 0.0011 19.2 0.9 0.0061 16.9 0.9 2.3 1 1 0 1 1 1 1 Galactose mutarotase-like Adeno_PV PF03910.13 EPS29020.1 - 0.36 9.5 0.9 0.61 8.7 0.9 1.2 1 0 0 1 1 1 0 Adenovirus minor core protein PV Zn_clus PF00172.18 EPS29021.1 - 2.1e-06 27.7 8.2 3.9e-06 26.9 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Homeobox_KN PF05920.11 EPS29024.1 - 8.9e-22 76.7 2.0 1.1e-21 76.5 0.2 2.0 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 EPS29024.1 - 2.4e-07 30.5 0.1 5.3e-07 29.4 0.1 1.6 1 0 0 1 1 1 1 Homeodomain FSIP2 PF15783.5 EPS29026.1 - 0.17 9.8 0.0 0.17 9.8 0.0 1.2 1 0 0 1 1 1 0 Fibrous sheath-interacting protein 2 P5CR_dimer PF14748.6 EPS29028.1 - 4.7e-35 119.9 1.5 1.2e-34 118.7 1.5 1.7 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 EPS29028.1 - 9.2e-18 64.6 0.2 2.3e-17 63.4 0.2 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 EPS29028.1 - 0.0028 17.7 0.2 0.0077 16.2 0.2 1.8 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 EPS29028.1 - 0.051 13.8 0.2 0.14 12.3 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 EPS29028.1 - 0.053 13.6 0.2 0.2 11.7 0.1 2.0 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ApbA PF02558.16 EPS29028.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA PDH PF02153.17 EPS29028.1 - 0.14 11.1 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase SinI PF08671.10 EPS29028.1 - 0.18 11.7 0.0 0.43 10.4 0.0 1.7 1 0 0 1 1 1 0 Anti-repressor SinI FAD_binding_1 PF00667.20 EPS29029.1 - 4.6e-43 147.3 0.0 6.7e-43 146.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EPS29029.1 - 7.7e-09 36.2 0.0 1.8e-08 35.0 0.0 1.6 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Peptidase_S64 PF08192.11 EPS29030.1 - 9.5e-07 27.7 0.0 1.5e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S64 Peptidase_S32 PF05579.13 EPS29030.1 - 0.041 13.1 0.1 0.065 12.4 0.1 1.2 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 bZIP_1 PF00170.21 EPS29031.1 - 0.011 15.8 10.1 0.038 14.1 4.0 2.2 1 1 1 2 2 2 0 bZIP transcription factor HAP1_N PF04849.13 EPS29031.1 - 0.022 14.0 2.3 0.033 13.4 2.3 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Fer4_23 PF18009.1 EPS29031.1 - 0.097 13.1 1.6 0.74 10.3 1.2 2.2 2 0 0 2 2 2 0 4Fe-4S iron-sulfur cluster binding domain bZIP_2 PF07716.15 EPS29031.1 - 4.5 7.4 9.7 6.2 7.0 7.7 2.0 1 1 1 2 2 2 0 Basic region leucine zipper Methyltransf_31 PF13847.6 EPS29032.1 - 7.9e-28 97.2 0.0 1.1e-27 96.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPS29032.1 - 4.5e-20 72.2 0.0 7.7e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS29032.1 - 1.9e-16 60.5 0.0 3.5e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPS29032.1 - 9.4e-13 48.0 0.0 1.6e-12 47.2 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EPS29032.1 - 2.1e-09 37.5 0.0 3e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPS29032.1 - 6e-08 33.3 0.0 1.1e-07 32.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EPS29032.1 - 1.2e-07 31.4 0.3 1.8e-07 30.9 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 EPS29032.1 - 2.4e-06 27.5 0.1 5.4e-06 26.3 0.1 1.6 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 EPS29032.1 - 0.0005 19.4 0.0 0.00073 18.9 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 EPS29032.1 - 0.0029 17.2 0.0 0.0045 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.18 EPS29032.1 - 0.0035 17.1 0.0 0.0056 16.4 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 DOT1 PF08123.13 EPS29032.1 - 0.0068 16.0 0.1 0.016 14.8 0.1 1.7 1 1 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_32 PF13679.6 EPS29032.1 - 0.057 13.4 0.0 0.083 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.15 EPS29032.1 - 0.075 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase Rsa3 PF14615.6 EPS29032.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Ribosome-assembly protein 3 Methyltransf_3 PF01596.17 EPS29032.1 - 0.12 11.5 0.0 0.31 10.2 0.0 1.7 1 1 0 1 1 1 0 O-methyltransferase Methyltransf_16 PF10294.9 EPS29032.1 - 0.21 11.3 0.1 0.37 10.5 0.1 1.3 1 0 0 1 1 1 0 Lysine methyltransferase LMWPc PF01451.21 EPS29033.1 - 1.4e-16 61.2 0.0 2.9e-16 60.1 0.0 1.5 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Myb_DNA-bind_6 PF13921.6 EPS29035.1 - 0.00012 22.2 0.0 0.00023 21.3 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EPS29035.1 - 0.0046 17.1 0.0 0.0081 16.3 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain AIF-MLS PF14962.6 EPS29035.1 - 0.12 12.3 2.7 0.26 11.2 2.7 1.5 1 0 0 1 1 1 0 Mitochondria Localisation Sequence Ses_B PF17046.5 EPS29036.1 - 0.0016 18.3 5.3 0.0041 17.0 5.3 1.7 1 0 0 1 1 1 1 SesB domain on fungal death-pathway protein CsiD PF08943.10 EPS29036.1 - 0.13 11.4 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 CsiD HHH PF00633.23 EPS29036.1 - 0.17 11.8 0.0 0.54 10.2 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif Ank_2 PF12796.7 EPS29038.1 - 3.5e-113 370.4 0.0 8.2e-16 58.4 0.0 9.1 2 2 7 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPS29038.1 - 1.6e-111 363.3 16.1 6.7e-13 48.9 0.0 16.0 3 2 13 16 16 16 14 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPS29038.1 - 9.4e-82 259.1 0.6 1.8e-05 24.8 0.0 16.2 16 0 0 16 16 15 14 Ankyrin repeat Ank PF00023.30 EPS29038.1 - 8.7e-81 263.1 0.2 2.4e-05 24.6 0.0 15.8 15 0 0 15 15 15 14 Ankyrin repeat Ank_5 PF13857.6 EPS29038.1 - 9.9e-65 213.8 6.4 1.4e-09 38.1 0.3 9.7 6 2 4 10 10 10 10 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.20 EPS29038.1 - 7e-06 25.5 0.0 1.4e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.12 EPS29038.1 - 1.4e-05 25.1 0.0 4.1e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EPS29038.1 - 0.0015 18.9 0.0 0.032 14.6 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EPS29038.1 - 0.0048 17.2 0.0 0.017 15.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain Mqo PF06039.15 EPS29038.1 - 0.078 11.5 0.0 82 1.6 0.0 4.2 3 3 4 7 7 7 0 Malate:quinone oxidoreductase (Mqo) RNA_helicase PF00910.22 EPS29038.1 - 0.1 13.0 0.0 0.28 11.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.6 EPS29038.1 - 0.14 11.9 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TM1506 PF08973.10 EPS29038.1 - 0.15 11.7 0.0 24 4.6 0.0 4.0 4 1 1 5 5 5 0 Domain of unknown function (DUF1893) AAA_10 PF12846.7 EPS29038.1 - 0.19 10.6 0.1 0.76 8.6 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain VWA_3_C PF18571.1 EPS29038.1 - 0.24 11.3 2.9 1.6e+02 2.2 0.0 5.8 9 0 0 9 9 9 0 von Willebrand factor type A C-terminal domain Exo_endo_phos_2 PF14529.6 EPS29039.1 - 2.1e-24 85.6 0.2 8.7e-24 83.7 0.2 2.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.27 EPS29039.1 - 4e-23 82.1 0.0 7.3e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.24 EPS29039.1 - 3.5e-09 37.0 0.1 8.9e-09 35.7 0.1 1.8 1 0 0 1 1 1 1 RNase H Exo_endo_phos PF03372.23 EPS29039.1 - 3.1e-06 26.9 0.3 4e-05 23.2 0.2 2.4 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family DivIC PF04977.15 EPS29039.1 - 0.044 13.6 2.4 0.13 12.0 2.4 1.8 1 0 0 1 1 1 0 Septum formation initiator CENP-H PF05837.12 EPS29039.1 - 0.056 13.9 6.4 0.61 10.5 0.4 3.2 2 0 0 2 2 2 0 Centromere protein H (CENP-H) DUF1664 PF07889.12 EPS29039.1 - 0.057 13.5 2.1 0.18 11.8 2.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) YabA PF06156.13 EPS29039.1 - 0.063 13.9 0.7 0.85 10.3 0.0 2.6 2 0 0 2 2 2 0 Initiation control protein YabA HALZ PF02183.18 EPS29039.1 - 0.081 13.2 0.6 0.2 11.9 0.6 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper Fez1 PF06818.15 EPS29039.1 - 0.17 12.3 6.5 0.49 10.8 0.1 2.5 2 0 0 2 2 2 0 Fez1 bZIP_2 PF07716.15 EPS29039.1 - 0.59 10.3 3.3 2.1 8.5 3.3 2.0 1 0 0 1 1 1 0 Basic region leucine zipper Golgin_A5 PF09787.9 EPS29039.1 - 0.78 9.1 6.1 0.1 12.1 0.9 2.0 2 0 0 2 2 2 0 Golgin subfamily A member 5 GAS PF13851.6 EPS29039.1 - 8.4 5.7 9.1 0.44 9.9 2.3 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding AAA_22 PF13401.6 EPS29040.1 - 0.0004 20.7 0.1 0.0042 17.4 0.0 2.7 2 1 0 3 3 3 1 AAA domain NACHT PF05729.12 EPS29040.1 - 0.0015 18.5 6.1 0.05 13.5 3.0 4.0 4 1 0 4 4 4 1 NACHT domain AAA_16 PF13191.6 EPS29040.1 - 0.0017 18.8 0.7 0.027 14.9 0.7 2.5 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 EPS29040.1 - 0.0056 15.9 0.0 0.051 12.8 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain KAP_NTPase PF07693.14 EPS29040.1 - 0.02 14.1 0.4 0.32 10.2 0.0 2.1 1 1 1 2 2 2 0 KAP family P-loop domain RNA_helicase PF00910.22 EPS29040.1 - 0.021 15.2 0.0 0.06 13.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 EPS29040.1 - 0.027 14.2 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoU_div PF01865.16 EPS29040.1 - 0.033 13.5 0.1 0.06 12.7 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF47 AAA_29 PF13555.6 EPS29040.1 - 0.04 13.6 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 EPS29040.1 - 0.073 13.6 0.0 0.24 11.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EPS29040.1 - 0.084 13.0 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EPS29040.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.9 EPS29041.1 - 0.051 12.5 0.1 0.07 12.0 0.1 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain APH PF01636.23 EPS29042.1 - 6e-12 46.0 0.0 1.8e-11 44.5 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family BCS1_N PF08740.11 EPS29046.1 - 8.5e-38 130.2 1.1 1.3e-37 129.7 1.1 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EPS29046.1 - 9.8e-17 61.6 0.0 2.3e-16 60.4 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) PPV_E1_C PF00519.17 EPS29046.1 - 0.0049 15.8 0.0 0.024 13.5 0.0 1.9 2 0 0 2 2 2 1 Papillomavirus helicase ATPase PF06745.13 EPS29046.1 - 0.016 14.6 0.0 0.033 13.5 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.6 EPS29046.1 - 0.022 14.3 0.0 0.047 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EPS29046.1 - 0.03 14.9 0.1 0.5 10.9 0.0 2.8 2 2 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EPS29046.1 - 0.06 13.3 0.1 0.32 11.0 0.0 2.2 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EPS29046.1 - 0.068 13.5 0.6 1.3 9.4 0.2 2.7 1 1 1 2 2 2 0 AAA ATPase domain AAA_33 PF13671.6 EPS29046.1 - 0.097 12.8 0.0 0.21 11.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EPS29046.1 - 0.12 12.6 0.0 1.6 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EPS29046.1 - 0.14 11.6 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EPS29046.1 - 0.15 11.7 0.1 0.5 10.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain IPT PF01745.16 EPS29046.1 - 0.17 11.3 0.0 0.37 10.1 0.0 1.6 1 0 0 1 1 1 0 Isopentenyl transferase HSDR_N_2 PF13588.6 EPS29047.1 - 0.081 12.9 0.0 0.83 9.7 0.0 2.4 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) Casc1_N PF15927.5 EPS29047.1 - 0.39 10.4 18.0 1.2 8.8 18.0 1.9 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus DUF1840 PF08895.11 EPS29047.1 - 6.5 7.1 6.2 22 5.5 6.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) Radial_spoke_3 PF06098.11 EPS29047.1 - 6.7 5.9 16.3 0.038 13.3 6.8 2.1 2 0 0 2 2 2 0 Radial spoke protein 3 Glu_dehyd_C PF16912.5 EPS29050.1 - 3 7.3 6.6 35 3.8 0.1 3.3 1 1 2 3 3 3 0 Glucose dehydrogenase C-terminus DUF1388 PF07142.12 EPS29050.1 - 6.3 6.9 6.1 11 6.0 1.2 2.4 2 0 0 2 2 2 0 Repeat of unknown function (DUF1388) DUF2247 PF10004.9 EPS29051.1 - 0.099 12.4 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) TPD PF14811.6 EPS29052.1 - 5e-19 68.5 0.0 9.3e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function TPD sequence-motif zf-C2H2_jaz PF12171.8 EPS29052.1 - 2.3e-12 46.9 5.7 3e-05 24.2 0.0 2.7 1 1 1 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EPS29052.1 - 1.5e-09 37.9 4.7 7.7e-05 23.0 0.0 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EPS29052.1 - 8.6e-05 23.1 4.4 0.26 12.2 0.0 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EPS29052.1 - 0.00014 22.1 6.6 0.038 14.4 0.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 EPS29052.1 - 0.0017 18.6 1.9 1 9.7 0.1 2.6 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 EPS29052.1 - 0.0031 17.5 1.9 0.11 12.6 0.0 2.4 1 1 1 2 2 2 1 C2H2-type zinc finger Sds3 PF08598.11 EPS29052.1 - 0.066 13.2 0.0 0.077 13.0 0.0 1.2 1 0 0 1 1 1 0 Sds3-like zf-DBF PF07535.12 EPS29052.1 - 0.076 13.1 5.0 1 9.5 3.4 2.4 1 1 1 2 2 2 0 DBF zinc finger WD40 PF00400.32 EPS29053.1 - 2e-56 186.6 31.2 2.7e-09 37.5 1.3 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS29053.1 - 1.9e-27 95.4 6.5 2.7e-05 24.4 0.1 7.1 2 1 5 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain NACHT PF05729.12 EPS29053.1 - 8.8e-23 81.0 0.0 1.6e-22 80.2 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Nup160 PF11715.8 EPS29053.1 - 2.2e-11 43.2 13.8 0.16 10.6 0.3 6.7 1 1 5 7 7 7 5 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EPS29053.1 - 1.7e-09 37.1 8.3 0.047 12.7 0.6 5.9 2 1 3 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_3 PF15911.5 EPS29053.1 - 0.00025 21.0 0.0 1.9 8.6 0.1 4.5 2 1 2 4 4 4 1 WD domain, G-beta repeat PD40 PF07676.12 EPS29053.1 - 0.00033 20.5 9.8 0.97 9.5 0.2 5.6 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 EPS29053.1 - 0.00079 18.8 8.0 11 5.2 0.1 5.3 1 1 4 6 6 6 1 Neuroblastoma-amplified sequence, N terminal AAA_16 PF13191.6 EPS29053.1 - 0.021 15.2 0.0 0.069 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain Coatomer_WDAD PF04053.14 EPS29053.1 - 0.026 13.6 2.9 3.1 6.7 0.1 2.8 1 1 0 2 2 2 0 Coatomer WD associated region AAA_19 PF13245.6 EPS29053.1 - 0.045 14.1 0.0 0.09 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain WD40_like PF17005.5 EPS29053.1 - 0.085 12.2 0.0 1.9 7.7 0.0 2.6 1 1 1 2 2 2 0 WD40-like domain RNA_helicase PF00910.22 EPS29053.1 - 0.094 13.1 0.0 1.2 9.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Ses_B PF17046.5 EPS29053.1 - 0.9 9.6 4.5 1.2 9.2 0.2 2.3 2 0 0 2 2 2 0 SesB domain on fungal death-pathway protein BIR PF00653.21 EPS29054.1 - 0.002 18.7 0.1 0.0033 18.0 0.1 1.4 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain Pkinase PF00069.25 EPS29056.1 - 1.3e-12 47.7 0.1 2.6e-12 46.7 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS29056.1 - 1.2e-08 34.6 0.0 2.1e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PNP_UDP_1 PF01048.20 EPS29056.1 - 0.0007 18.9 0.9 0.0049 16.2 0.9 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily WD40 PF00400.32 EPS29057.1 - 1.2e-33 114.5 15.1 3.4e-11 43.5 1.3 5.0 4 0 0 4 4 4 4 WD domain, G-beta repeat NACHT PF05729.12 EPS29057.1 - 6.6e-26 91.2 0.0 1.2e-25 90.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain ANAPC4_WD40 PF12894.7 EPS29057.1 - 1.8e-14 53.8 0.1 1.9e-05 24.9 0.0 4.3 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EPS29057.1 - 8.8e-08 31.9 9.6 0.38 10.7 0.0 4.5 4 0 0 4 4 4 4 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 EPS29057.1 - 0.00014 21.0 0.1 1.4 7.8 0.0 3.6 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Ses_B PF17046.5 EPS29057.1 - 0.006 16.5 0.2 0.006 16.5 0.2 2.0 2 0 0 2 2 2 1 SesB domain on fungal death-pathway protein eIF2A PF08662.11 EPS29057.1 - 0.0076 16.2 0.0 2.4 8.0 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EPS29057.1 - 0.014 14.1 0.1 0.93 8.1 0.1 2.9 1 1 2 3 3 3 0 Nucleoporin Nup120/160 AAA_16 PF13191.6 EPS29057.1 - 0.03 14.7 0.0 0.088 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain IKI3 PF04762.12 EPS29057.1 - 0.048 11.7 1.6 0.19 9.7 1.5 1.8 1 1 0 1 1 1 0 IKI3 family PALB2_WD40 PF16756.5 EPS29057.1 - 0.14 11.1 1.6 0.49 9.3 0.2 2.3 1 1 3 4 4 4 0 Partner and localizer of BRCA2 WD40 domain DUF4082 PF13313.6 EPS29057.1 - 0.27 11.3 4.6 4.3 7.4 0.0 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4082) DUF3435 PF11917.8 EPS29058.1 - 2.1e-142 474.9 4.7 3.1e-142 474.4 4.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Hexose_dehydrat PF03559.14 EPS29058.1 - 0.076 12.4 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 NDP-hexose 2,3-dehydratase Phage_int_SAM_4 PF13495.6 EPS29058.1 - 0.093 13.2 0.3 8.8 6.9 0.0 3.6 3 1 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain Collagen PF01391.18 EPS29059.1 - 0.039 13.7 0.6 0.063 13.0 0.6 1.2 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) MFS_1 PF07690.16 EPS29061.1 - 5.2e-35 121.0 40.9 8.8e-35 120.2 39.9 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EPS29061.1 - 2e-12 46.4 12.6 2.5e-12 46.0 12.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FtsH_ext PF06480.15 EPS29061.1 - 0.053 13.9 1.0 0.19 12.1 0.1 2.6 2 0 0 2 2 2 0 FtsH Extracellular Zn_clus PF00172.18 EPS29062.1 - 9.5e-05 22.4 11.0 0.00017 21.6 11.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UPF0506 PF11703.8 EPS29062.1 - 0.8 10.1 7.7 1.8 9.0 7.7 1.5 1 0 0 1 1 1 0 UPF0506 TERB2 PF15101.6 EPS29063.1 - 0.11 12.5 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 HLH PF00010.26 EPS29065.1 - 1.3e-09 37.8 0.6 1.3e-08 34.6 0.0 2.4 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain SPT16 PF08644.11 EPS29065.1 - 0.047 13.9 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) Helitron_like_N PF14214.6 EPS29066.1 - 2.3e-24 86.7 0.0 4e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.14 EPS29066.1 - 6.9e-16 58.4 0.0 1.1e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 EPS29066.1 - 2.6e-11 43.6 0.0 6.1e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EPS29066.1 - 2.4e-06 27.9 0.0 7.7e-06 26.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain p450 PF00067.22 EPS29067.1 - 9.6e-58 196.0 0.0 3.1e-49 168.0 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.22 EPS29068.1 - 5.1e-30 104.6 0.0 2.4e-29 102.4 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.28 EPS29069.1 - 5.1e-79 265.8 0.0 9.3e-79 265.0 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.26 EPS29069.1 - 1.7e-74 250.6 0.0 4e-74 249.4 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.20 EPS29069.1 - 3.3e-69 233.8 0.1 5.6e-69 233.0 0.1 1.3 1 0 0 1 1 1 1 Condensation domain KR PF08659.10 EPS29069.1 - 7.2e-51 172.7 0.1 4.9e-50 169.9 0.1 2.3 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 EPS29069.1 - 5.5e-48 163.7 0.1 1.4e-47 162.4 0.0 1.7 2 0 0 2 2 2 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 EPS29069.1 - 2.7e-44 152.0 2.7 2.7e-44 152.0 2.7 2.3 2 0 0 2 2 2 1 Acyl transferase domain NAD_binding_4 PF07993.12 EPS29069.1 - 2.8e-35 121.7 0.0 6.4e-33 114.0 0.0 2.8 1 1 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.22 EPS29069.1 - 9.6e-30 103.0 0.0 3.3e-29 101.3 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Epimerase PF01370.21 EPS29069.1 - 3.2e-19 69.3 0.0 4.2e-16 59.2 0.0 3.2 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family Methyltransf_12 PF08242.12 EPS29069.1 - 8.3e-19 68.2 0.5 6.7e-18 65.3 0.0 2.8 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPS29069.1 - 2.1e-16 60.2 0.0 8.1e-15 55.0 0.0 3.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPS29069.1 - 2.8e-15 56.8 0.1 6.4e-14 52.4 0.0 3.4 3 0 0 3 3 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EPS29069.1 - 2.9e-14 53.5 0.0 8.7e-14 51.9 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PP-binding PF00550.25 EPS29069.1 - 6.9e-13 48.8 4.7 4.7e-07 30.1 0.2 3.2 3 0 0 3 3 2 2 Phosphopantetheine attachment site Methyltransf_11 PF08241.12 EPS29069.1 - 7.2e-13 49.0 0.0 4.4e-12 46.5 0.0 2.6 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 EPS29069.1 - 7.7e-13 48.3 0.5 2.9e-10 39.9 0.1 2.7 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_31 PF13847.6 EPS29069.1 - 4.3e-11 42.8 0.0 7.5e-10 38.8 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPS29069.1 - 2.7e-09 36.7 0.0 6.2e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NAD_binding_10 PF13460.6 EPS29069.1 - 1.1e-06 28.7 0.0 0.0003 20.7 0.0 2.6 2 0 0 2 2 2 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EPS29069.1 - 4.2e-06 26.0 0.0 0.00023 20.3 0.0 2.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_16 PF10294.9 EPS29069.1 - 1.3e-05 25.0 0.0 3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase GDP_Man_Dehyd PF16363.5 EPS29069.1 - 3.8e-05 23.2 0.1 0.0035 16.8 0.0 2.3 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Thiolase_N PF00108.23 EPS29069.1 - 5.7e-05 22.6 0.0 0.00013 21.4 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain RrnaAD PF00398.20 EPS29069.1 - 0.003 16.7 0.0 0.0063 15.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.19 EPS29069.1 - 0.003 17.3 0.9 0.049 13.4 0.1 2.7 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Polysacc_synt_2 PF02719.15 EPS29069.1 - 0.013 14.6 0.1 1.3 8.1 0.0 2.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NodS PF05401.11 EPS29069.1 - 0.018 14.7 0.0 0.048 13.3 0.0 1.7 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_24 PF13578.6 EPS29069.1 - 0.02 15.9 0.0 0.11 13.6 0.0 2.4 1 0 0 1 1 1 0 Methyltransferase domain Sacchrp_dh_NADP PF03435.18 EPS29069.1 - 0.023 15.0 0.1 2.6 8.3 0.0 3.5 3 0 0 3 3 3 0 Saccharopine dehydrogenase NADP binding domain DREV PF05219.12 EPS29069.1 - 0.06 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase DUF2201 PF09967.9 EPS29069.1 - 0.14 12.3 0.1 3.5 7.8 0.0 2.9 2 0 0 2 2 2 0 VWA-like domain (DUF2201) Semialdhyde_dh PF01118.24 EPS29069.1 - 0.16 12.4 0.0 0.74 10.3 0.0 2.2 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 4HBT_2 PF13279.6 EPS29070.1 - 3.4e-07 30.8 0.0 6.4e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Thioesterase-like superfamily ADH_zinc_N_2 PF13602.6 EPS29071.1 - 7.9e-23 82.0 0.0 2e-22 80.6 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EPS29071.1 - 4.5e-08 33.1 0.0 8.9e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.6 EPS29072.1 - 1.3e-09 38.3 0.0 2.8e-09 37.1 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EPS29072.1 - 2.2e-09 37.2 0.0 5.5e-06 26.1 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family WD40 PF00400.32 EPS29073.1 - 2e-15 56.9 6.0 0.008 17.0 0.0 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS29073.1 - 8.2e-08 32.4 0.0 0.25 11.7 0.0 4.5 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EPS29073.1 - 0.074 12.0 0.8 11 4.9 0.0 3.3 2 2 2 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein FmdE PF02663.14 EPS29073.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Aminotran_4 PF01063.19 EPS29075.1 - 5.3e-25 88.6 0.0 8.6e-25 87.9 0.0 1.3 2 0 0 2 2 2 1 Amino-transferase class IV p450 PF00067.22 EPS29076.1 - 9e-74 248.9 0.0 1.1e-73 248.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1100 PF06500.11 EPS29078.1 - 6.3e-10 38.4 0.0 8.9e-10 37.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_6 PF12697.7 EPS29078.1 - 9.6e-08 32.9 3.6 9.6e-08 32.9 3.6 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPS29078.1 - 0.00014 21.2 0.2 0.00067 19.0 0.1 2.0 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 EPS29078.1 - 0.0009 19.0 0.2 0.0027 17.4 0.1 1.7 1 1 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 EPS29078.1 - 0.0014 18.2 0.1 0.0031 17.0 0.1 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.12 EPS29078.1 - 0.0037 16.0 0.1 0.043 12.5 0.1 2.1 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 EPS29078.1 - 0.019 14.7 0.1 0.29 10.7 0.1 2.2 1 1 0 2 2 2 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 EPS29078.1 - 0.026 13.4 0.0 0.039 12.9 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_3 PF07859.13 EPS29078.1 - 0.081 12.8 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Chlorophyllase PF07224.11 EPS29078.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Peptidase_S15 PF02129.18 EPS29078.1 - 0.12 12.0 0.4 4.8 6.7 0.2 2.5 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.11 EPS29078.1 - 0.12 12.3 0.0 0.33 10.8 0.0 1.6 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 EPS29078.1 - 0.18 11.3 0.0 0.52 9.8 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family ADH_zinc_N PF00107.26 EPS29079.1 - 6.7e-06 26.1 0.0 1.2e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPS29079.1 - 1.6e-05 26.0 0.0 2.5e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPS29079.1 - 0.0062 16.4 0.0 0.027 14.3 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Benyvirus_P25 PF05744.11 EPS29080.1 - 0.02 14.2 0.1 0.034 13.4 0.1 1.3 1 0 0 1 1 1 0 Benyvirus P25/P26 protein PALP PF00291.25 EPS29082.1 - 5.2e-67 226.3 0.0 6.7e-67 226.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 EPS29082.1 - 2.4e-12 47.1 0.0 3.5e-08 33.8 0.0 3.2 3 0 0 3 3 3 2 CBS domain adh_short PF00106.25 EPS29083.1 - 3.2e-23 82.2 0.0 1.3e-21 77.0 0.1 2.2 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS29083.1 - 2.8e-11 43.4 0.0 3.9e-10 39.7 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPS29083.1 - 2e-10 40.9 0.0 2.8e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EPS29083.1 - 0.0046 16.1 0.1 0.0069 15.6 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EPS29083.1 - 0.018 14.5 0.1 0.028 13.9 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EPS29083.1 - 0.053 12.9 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase RNA_helicase PF00910.22 EPS29083.1 - 0.18 12.2 0.0 2 8.8 0.0 2.2 2 0 0 2 2 2 0 RNA helicase SRPRB PF09439.10 EPS29084.1 - 1.2e-22 80.3 1.7 4.7e-21 75.0 1.7 2.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 EPS29084.1 - 0.00011 21.8 0.3 0.012 15.0 0.0 2.6 2 1 0 2 2 2 1 ADP-ribosylation factor family AAA_16 PF13191.6 EPS29084.1 - 0.0077 16.6 0.1 0.015 15.7 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activat PF00158.26 EPS29084.1 - 0.014 15.1 0.0 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_29 PF13555.6 EPS29084.1 - 0.048 13.4 0.1 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EPS29084.1 - 0.049 13.9 0.1 0.088 13.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EPS29084.1 - 0.085 12.8 0.1 0.15 12.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 EPS29084.1 - 0.1 12.5 1.1 1.3 8.9 0.5 2.3 2 0 0 2 2 2 0 RsgA GTPase ATP_bind_1 PF03029.17 EPS29084.1 - 0.21 11.4 0.2 10 5.8 0.0 2.4 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein GPI-anchored PF10342.9 EPS29085.1 - 8.8e-07 29.6 0.1 2.4e-06 28.2 0.0 1.7 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family KRE9 PF05390.11 EPS29085.1 - 0.14 12.9 5.2 0.38 11.5 5.2 1.7 1 1 0 1 1 1 0 Yeast cell wall synthesis protein KRE9/KNH1 AA_kinase PF00696.28 EPS29086.1 - 2.7e-40 138.5 0.6 3.4e-40 138.1 0.6 1.1 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 EPS29086.1 - 5.9e-19 67.8 0.1 8.4e-18 64.1 0.0 2.4 2 0 0 2 2 2 1 PUA domain Peptidase_M76 PF09768.9 EPS29087.1 - 5e-74 247.7 2.4 6e-74 247.5 2.4 1.1 1 0 0 1 1 1 1 Peptidase M76 family HNH_5 PF14279.6 EPS29087.1 - 0.04 13.8 0.5 0.4 10.6 0.0 2.4 2 0 0 2 2 2 0 HNH endonuclease SprT-like PF10263.9 EPS29087.1 - 0.058 13.3 2.7 0.064 13.1 1.1 1.7 1 1 1 2 2 2 0 SprT-like family Peptidase_M91 PF14891.6 EPS29087.1 - 0.095 13.0 0.1 0.16 12.3 0.1 1.4 1 0 0 1 1 1 0 Effector protein Pkinase PF00069.25 EPS29088.1 - 1.7e-70 237.4 0.0 2.2e-70 237.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS29088.1 - 1.1e-43 149.4 0.0 1.5e-43 149.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EPS29088.1 - 3.2e-07 29.9 0.0 1.2e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EPS29088.1 - 7.5e-05 22.2 0.2 0.00014 21.3 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EPS29088.1 - 0.0046 15.9 0.2 0.0073 15.3 0.2 1.4 1 1 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 EPS29088.1 - 0.055 13.1 0.0 0.2 11.2 0.0 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EPS29088.1 - 0.063 13.2 0.1 0.091 12.7 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 EPS29088.1 - 0.078 12.6 0.0 0.22 11.1 0.0 1.7 1 1 1 2 2 2 0 RIO1 family YrbL-PhoP_reg PF10707.9 EPS29088.1 - 0.12 11.9 0.1 0.29 10.6 0.1 1.8 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL TIP41 PF04176.13 EPS29089.1 - 2.4e-72 242.0 0.0 2.8e-72 241.8 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family DUF4279 PF14106.6 EPS29089.1 - 0.1 12.8 0.1 1.4 9.2 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4279) Orn_Arg_deC_N PF02784.16 EPS29090.1 - 6.6e-34 117.4 0.0 8e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EPS29090.1 - 1.2e-16 60.7 0.0 1.4e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain DUF3098 PF11297.8 EPS29090.1 - 0.071 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3098) Dak1 PF02733.17 EPS29091.1 - 5.6e-100 334.2 0.0 8.8e-100 333.6 0.0 1.3 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 EPS29091.1 - 1.3e-37 129.4 0.9 2.2e-37 128.7 0.9 1.4 1 0 0 1 1 1 1 DAK2 domain CitMHS PF03600.16 EPS29092.1 - 0.14 11.4 7.1 0.17 11.0 7.1 1.1 1 0 0 1 1 1 0 Citrate transporter Ubiq_cyt_C_chap PF03981.12 EPS29093.1 - 6.5e-36 123.5 0.1 2.5e-35 121.6 0.1 1.8 2 0 0 2 2 2 1 Ubiquinol-cytochrome C chaperone Peptidase_M1 PF01433.20 EPS29094.1 - 1.6e-47 161.9 0.6 2.2e-47 161.4 0.6 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 EPS29094.1 - 2.1e-35 121.2 0.0 4.2e-35 120.2 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 EPS29094.1 - 9e-30 104.2 0.3 1.5e-29 103.6 0.3 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_MA_2 PF13485.6 EPS29094.1 - 0.012 15.3 0.1 0.21 11.2 0.1 2.2 2 0 0 2 2 2 0 Peptidase MA superfamily Peptidase_M61 PF05299.12 EPS29094.1 - 0.31 11.4 2.1 8.4 6.8 2.1 2.7 1 1 0 1 1 1 0 M61 glycyl aminopeptidase MIT PF04212.18 EPS29096.1 - 4.6e-13 49.0 0.9 1.1e-12 47.8 0.9 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Zn_clus PF00172.18 EPS29097.1 - 2.3e-08 34.0 7.0 4e-08 33.2 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CAF1A PF12253.8 EPS29098.1 - 0.068 13.4 0.3 0.2 11.8 0.3 1.8 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A FlbD PF06289.11 EPS29098.1 - 0.086 12.5 0.5 0.14 11.8 0.5 1.3 1 0 0 1 1 1 0 Flagellar and Swarming motility proteins Peptidase_M24 PF00557.24 EPS29099.1 - 6.2e-55 186.1 0.1 9.1e-55 185.6 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EPS29099.1 - 4.7e-29 100.6 0.0 1e-28 99.5 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain BTB PF00651.31 EPS29100.1 - 0.00079 19.6 0.1 0.0038 17.4 0.0 2.1 2 1 0 2 2 2 1 BTB/POZ domain MBOAT PF03062.19 EPS29101.1 - 5e-53 180.7 22.1 1.2e-51 176.1 21.5 2.3 2 1 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family DLH PF01738.18 EPS29102.1 - 3.4e-31 108.5 0.0 3.9e-31 108.3 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 EPS29102.1 - 0.00079 20.1 0.2 0.00088 19.9 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 EPS29102.1 - 0.0081 15.9 0.0 0.17 11.6 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.11 EPS29102.1 - 0.012 15.0 0.0 0.33 10.2 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.20 EPS29102.1 - 0.11 12.1 0.0 0.34 10.5 0.0 1.8 1 1 1 2 2 2 0 alpha/beta hydrolase fold CH PF00307.31 EPS29103.1 - 1.1e-74 247.6 0.0 1.3e-21 76.8 0.1 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 EPS29103.1 - 4.7e-05 23.8 1.4 0.00049 20.5 0.2 2.9 3 0 0 3 3 3 1 EF-hand domain pair CAMSAP_CH PF11971.8 EPS29103.1 - 0.00041 20.1 0.0 0.3 10.9 0.0 3.4 3 0 0 3 3 3 1 CAMSAP CH domain EF-hand_6 PF13405.6 EPS29103.1 - 0.016 15.1 1.0 0.89 9.7 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain DDHD PF02862.17 EPS29104.1 - 6.9e-58 196.4 9.0 9e-58 196.1 0.0 3.5 2 1 0 2 2 2 1 DDHD domain PGAP1 PF07819.13 EPS29104.1 - 0.11 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein 4HBT PF03061.22 EPS29105.1 - 3.6e-13 49.7 0.1 5.3e-13 49.1 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 EPS29105.1 - 0.00057 20.0 0.0 0.00074 19.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT_3 PF13622.6 EPS29105.1 - 0.045 14.0 0.1 0.059 13.6 0.1 1.3 1 0 0 1 1 1 0 Thioesterase-like superfamily PXA PF02194.15 EPS29106.1 - 9.3e-35 120.2 0.8 2.3e-34 119.0 0.8 1.7 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 EPS29106.1 - 1.4e-24 86.9 0.1 7.1e-24 84.5 0.0 2.4 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 EPS29106.1 - 7.1e-09 35.6 0.4 9.5e-08 32.0 0.1 2.4 2 0 0 2 2 2 1 PX domain PC4 PF02229.16 EPS29107.1 - 1.1e-24 85.8 0.1 1.8e-24 85.1 0.1 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) DUF5386 PF17360.2 EPS29107.1 - 0.029 14.3 0.2 0.055 13.4 0.1 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5386) DUF4612 PF15389.6 EPS29107.1 - 0.063 14.3 1.4 0.12 13.4 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4612) Hydantoinase_B PF02538.14 EPS29108.1 - 6.3e-228 757.4 0.0 8.1e-228 757.0 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EPS29108.1 - 4.4e-101 338.0 0.0 4.4e-101 338.0 0.0 1.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EPS29108.1 - 1.1e-59 201.1 0.5 5.7e-58 195.6 0.0 2.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region RRM_1 PF00076.22 EPS29109.1 - 8.7e-12 44.7 0.0 1.2e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EPS29109.1 - 0.00061 19.7 0.0 0.00086 19.3 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Mito_carr PF00153.27 EPS29110.1 - 4.9e-75 247.6 2.4 1.8e-24 85.5 0.0 3.5 4 0 0 4 4 4 3 Mitochondrial carrier protein Serine_protease PF18405.1 EPS29110.1 - 0.001 18.3 0.2 0.022 13.9 0.0 2.8 2 1 2 4 4 4 1 Gammaproteobacterial serine protease Ribosomal_L18 PF17135.4 EPS29111.1 - 6.7e-93 309.3 3.4 7.5e-93 309.1 3.4 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 EPS29111.1 - 0.00079 20.1 0.2 0.00079 20.1 0.2 2.1 2 1 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A REC104 PF17378.2 EPS29111.1 - 0.18 11.6 0.0 0.24 11.2 0.0 1.1 1 0 0 1 1 1 0 Meiotic recombination protein REC104 Aldedh PF00171.22 EPS29112.1 - 8.3e-14 50.9 15.0 1.8e-12 46.5 10.2 2.7 2 1 0 2 2 2 2 Aldehyde dehydrogenase family E1_dh PF00676.20 EPS29112.1 - 0.048 12.6 0.0 0.082 11.8 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component URO-D PF01208.17 EPS29112.1 - 0.058 12.5 0.1 0.094 11.8 0.1 1.2 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) Polyoma_coat2 PF00761.20 EPS29112.1 - 0.061 13.0 2.6 4.7 6.8 0.3 2.2 2 0 0 2 2 2 0 Polyomavirus coat protein DUF1487 PF07368.11 EPS29112.1 - 0.064 12.7 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) PCI PF01399.27 EPS29113.1 - 0.001 19.5 0.0 0.0066 16.9 0.0 2.2 2 0 0 2 2 2 1 PCI domain Na_Ca_ex PF01699.24 EPS29116.1 - 3.7e-23 82.2 30.5 6.8e-14 52.1 7.8 2.3 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Archease PF01951.16 EPS29116.1 - 0.041 14.1 0.2 0.072 13.3 0.2 1.4 1 0 0 1 1 1 0 Archease protein family (MTH1598/TM1083) DUF3185 PF11381.8 EPS29116.1 - 0.18 11.8 3.0 1.5 8.8 0.5 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3185) MPS2 PF17060.5 EPS29117.1 - 0.00086 18.7 4.8 0.0019 17.5 4.8 1.5 1 0 0 1 1 1 1 Monopolar spindle protein 2 HAUS-augmin3 PF14932.6 EPS29117.1 - 0.0012 18.4 8.6 0.0012 18.4 8.6 2.6 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 3 DUF3606 PF12244.8 EPS29117.1 - 0.063 13.2 0.0 0.31 11.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) Striatin PF08232.12 EPS29117.1 - 0.35 11.5 11.7 0.026 15.1 6.1 1.9 2 0 0 2 2 2 0 Striatin family FAM76 PF16046.5 EPS29117.1 - 1.4 8.2 9.0 2.5 7.4 6.2 2.6 2 1 1 3 3 3 0 FAM76 protein V_ATPase_I PF01496.19 EPS29117.1 - 1.8 6.4 6.6 3.4 5.5 0.2 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DASH_Hsk3 PF08227.11 EPS29117.1 - 3.5 8.0 8.4 7.4 7.0 0.7 3.9 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like Cyclin PF08613.11 EPS29121.1 - 1.8e-34 119.5 0.0 2.3e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EPS29121.1 - 0.001 18.8 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain DHHC PF01529.20 EPS29122.1 - 2.7e-34 118.1 5.5 2.7e-34 118.1 5.5 2.4 2 1 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 EPS29122.1 - 3.3e-29 101.3 0.2 1.7e-11 44.6 0.0 3.8 2 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EPS29122.1 - 2.7e-23 81.7 2.7 9.5e-06 25.8 0.0 4.9 2 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPS29122.1 - 1.9e-20 70.8 2.4 3.8e-07 29.9 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 EPS29122.1 - 5e-19 67.8 1.5 1.5e-06 28.4 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 EPS29122.1 - 6.5e-17 61.7 1.4 0.0002 21.8 0.0 4.2 1 1 4 5 5 5 5 Ankyrin repeats (many copies) K_oxygenase PF13434.6 EPS29124.1 - 1.2e-113 379.8 0.0 1.4e-113 379.6 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EPS29124.1 - 5.8e-05 22.5 0.0 0.0014 17.9 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EPS29124.1 - 8.6e-05 21.9 0.1 0.0027 17.0 0.0 2.7 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Condensation PF00668.20 EPS29125.1 - 1.9e-204 679.5 1.3 4.9e-43 147.5 1.2 7.0 6 2 0 6 6 6 6 Condensation domain AMP-binding PF00501.28 EPS29125.1 - 3e-177 589.5 0.0 7.2e-83 278.5 0.0 4.3 4 0 0 4 4 4 4 AMP-binding enzyme PP-binding PF00550.25 EPS29125.1 - 2.9e-58 194.1 14.7 5.9e-11 42.6 0.2 7.4 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EPS29125.1 - 1.6e-08 35.4 0.0 5.7e-05 24.0 0.0 3.5 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain DUF4549 PF15082.6 EPS29125.1 - 0.16 11.8 0.0 0.43 10.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4549) Pkinase PF00069.25 EPS29126.1 - 9.7e-43 146.4 0.0 1.3e-41 142.8 0.0 2.1 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS29126.1 - 1.4e-26 93.4 0.0 2.4e-26 92.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase OB_NTP_bind PF07717.16 EPS29128.1 - 1.4e-21 76.7 0.0 5.9e-21 74.6 0.0 2.2 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EPS29128.1 - 1e-19 70.8 0.0 1e-19 70.8 0.0 3.9 4 1 0 4 4 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EPS29128.1 - 2.8e-13 50.2 0.0 7e-13 48.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EPS29128.1 - 4.6e-06 26.5 0.1 1.4e-05 24.9 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EPS29128.1 - 8.7e-05 22.8 0.1 0.00042 20.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EPS29128.1 - 0.00019 21.2 0.1 0.00051 19.8 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EPS29128.1 - 0.0003 21.1 0.1 0.0007 20.0 0.1 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EPS29128.1 - 0.00032 19.8 0.0 0.00069 18.8 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Sigma54_activ_2 PF14532.6 EPS29128.1 - 0.02 15.0 0.0 0.061 13.4 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain PWI PF01480.17 EPS29128.1 - 0.052 13.9 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 PWI domain AAA_23 PF13476.6 EPS29128.1 - 0.066 13.7 0.0 0.066 13.7 0.0 3.6 1 1 1 2 2 1 0 AAA domain SRP54 PF00448.22 EPS29128.1 - 0.11 12.1 0.1 0.24 11.0 0.1 1.7 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PsbU PF06514.11 EPS29128.1 - 0.14 12.2 0.0 2.7 8.1 0.0 2.6 2 0 0 2 2 2 0 Photosystem II 12 kDa extrinsic protein (PsbU) ABC_tran PF00005.27 EPS29128.1 - 0.38 11.3 1.4 0.86 10.1 0.1 2.3 1 1 1 2 2 2 0 ABC transporter Cyt-b5 PF00173.28 EPS29129.1 - 1.1e-22 80.0 0.1 1.2e-22 79.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain EFP_N PF08207.12 EPS29129.1 - 0.017 15.1 0.1 0.027 14.5 0.1 1.3 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain V-ATPase_H_C PF11698.8 EPS29129.1 - 0.043 13.9 0.0 0.053 13.6 0.0 1.2 1 0 0 1 1 1 0 V-ATPase subunit H Mcp5_PH PF12814.7 EPS29130.1 - 3.8e-45 152.9 0.0 7.9e-45 151.9 0.0 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology Fez1 PF06818.15 EPS29130.1 - 1.4e-06 28.9 15.4 3.1e-06 27.8 15.4 1.5 1 0 0 1 1 1 1 Fez1 TPR_MLP1_2 PF07926.12 EPS29130.1 - 0.0024 17.9 20.1 0.011 15.8 15.3 2.3 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein Exonuc_VII_L PF02601.15 EPS29130.1 - 0.078 12.5 8.3 0.14 11.7 8.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-F_leu_zip PF10473.9 EPS29130.1 - 0.17 11.9 12.5 0.3 11.1 12.5 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 STAT_alpha PF01017.20 EPS29130.1 - 0.56 10.1 6.1 1 9.2 6.1 1.4 1 0 0 1 1 1 0 STAT protein, all-alpha domain MIP-T3_C PF17749.1 EPS29130.1 - 0.67 9.9 9.2 1.4 8.9 9.2 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 C-terminal region Golgin_A5 PF09787.9 EPS29130.1 - 0.97 8.8 13.8 1.7 8.0 13.8 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 GAS PF13851.6 EPS29130.1 - 1.3 8.4 18.2 13 5.0 14.7 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding UPF0242 PF06785.11 EPS29130.1 - 4.4 7.4 9.0 7.5 6.6 9.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4407 PF14362.6 EPS29130.1 - 5.6 6.2 9.2 9.5 5.5 9.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF724 PF05266.14 EPS29130.1 - 7.4 6.3 12.3 0.16 11.8 5.4 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF724) Atg14 PF10186.9 EPS29130.1 - 8.9 5.3 12.3 2.3 7.2 6.9 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 HAD_2 PF13419.6 EPS29131.1 - 2.1e-09 37.7 0.0 3e-09 37.2 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EPS29131.1 - 3e-09 37.5 0.0 4.1e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EPS29131.1 - 2.6e-05 24.2 0.0 5.4e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like FKBP_C PF00254.28 EPS29132.1 - 8.3e-29 99.8 0.0 9.7e-29 99.5 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Ras PF00071.22 EPS29134.1 - 1.5e-51 174.2 0.9 1.3e-50 171.1 0.9 1.9 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EPS29134.1 - 2.5e-18 66.4 0.1 2.3e-17 63.3 0.1 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPS29134.1 - 0.00055 19.4 0.2 0.0041 16.6 0.1 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family FeoB_N PF02421.18 EPS29134.1 - 0.011 15.2 0.4 0.25 10.9 0.0 2.5 2 1 1 3 3 3 0 Ferrous iron transport protein B SRPRB PF09439.10 EPS29134.1 - 0.015 14.7 0.1 0.64 9.4 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EPS29134.1 - 0.093 12.6 0.0 9.3 6.1 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Septin PF00735.18 EPS29134.1 - 0.12 11.7 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_25 PF13481.6 EPS29134.1 - 0.12 11.9 0.1 0.32 10.5 0.1 1.7 2 1 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 EPS29134.1 - 0.2 11.2 0.3 4.4 6.8 0.1 2.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain I_LWEQ PF01608.17 EPS29135.1 - 0.042 14.1 0.0 0.054 13.7 0.0 1.2 1 0 0 1 1 1 0 I/LWEQ domain AMP-binding PF00501.28 EPS29136.1 - 2.2e-72 244.0 0.0 2.9e-72 243.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EPS29136.1 - 9.7e-17 60.6 0.1 2.9e-16 59.1 0.1 1.9 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 EPS29136.1 - 1e-13 52.0 0.0 3.2e-13 50.4 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GAF_2 PF13185.6 EPS29137.1 - 0.14 12.4 0.1 0.48 10.7 0.1 1.9 1 1 0 1 1 1 0 GAF domain Flocculin_t3 PF13928.6 EPS29139.1 - 0.0061 17.1 6.2 0.0061 17.1 6.2 3.3 1 1 2 3 3 3 1 Flocculin type 3 repeat Integrase_Zn PF02022.19 EPS29139.1 - 0.057 13.4 0.3 0.11 12.5 0.3 1.4 1 0 0 1 1 1 0 Integrase Zinc binding domain zf-C2H2 PF00096.26 EPS29140.1 - 2.2e-19 68.7 36.0 0.011 16.2 0.3 7.3 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPS29140.1 - 2.3e-16 59.1 30.2 0.057 14.3 1.0 7.4 7 0 0 7 7 7 6 C2H2-type zinc finger zf-met PF12874.7 EPS29140.1 - 3.8e-14 52.5 28.0 5.9e-05 23.3 2.5 6.4 6 0 0 6 6 6 5 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EPS29140.1 - 2.6e-11 43.5 24.5 1.5e-05 25.1 1.4 5.5 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EPS29140.1 - 1.4e-09 38.2 28.7 0.054 13.8 0.7 6.8 1 1 4 6 6 6 5 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 EPS29140.1 - 1.6e-09 37.4 15.1 0.0013 18.5 0.3 5.6 5 0 0 5 5 5 3 zinc-finger C2H2-type zf-C2H2_6 PF13912.6 EPS29140.1 - 2.7e-07 30.4 29.8 0.026 14.5 0.0 6.8 7 0 0 7 7 6 4 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EPS29140.1 - 5.2e-05 23.5 27.4 0.027 14.9 0.8 7.3 7 0 0 7 7 7 2 Zinc-finger double domain Rad50_zn_hook PF04423.14 EPS29140.1 - 0.12 12.2 10.2 1.1 9.1 0.0 4.7 4 1 1 5 5 5 0 Rad50 zinc hook motif zf-DBF PF07535.12 EPS29140.1 - 0.13 12.4 12.3 1.2 9.3 1.0 4.0 3 0 0 3 3 3 0 DBF zinc finger Zn-ribbon_8 PF09723.10 EPS29140.1 - 0.18 12.0 22.7 0.62 10.2 1.1 5.5 4 2 1 5 5 5 0 Zinc ribbon domain DUF1360 PF07098.11 EPS29140.1 - 1.1 9.3 3.2 7.2 6.6 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1360) C1_4 PF07975.12 EPS29140.1 - 1.4 9.2 21.7 6 7.2 2.3 4.4 2 1 3 5 5 5 0 TFIIH C1-like domain SHMT PF00464.19 EPS29141.1 - 3.3e-200 664.8 0.0 3.8e-200 664.6 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase MOSC PF03473.17 EPS29142.1 - 6.3e-31 107.1 0.0 1e-30 106.4 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 EPS29142.1 - 1.4e-15 57.3 0.0 3e-14 52.9 0.0 2.2 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain Patatin PF01734.22 EPS29143.1 - 1.6e-14 54.6 0.0 4.3e-14 53.2 0.0 1.7 1 1 0 1 1 1 1 Patatin-like phospholipase Corona_NS2A PF05213.12 EPS29143.1 - 0.083 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Coronavirus NS2A protein Mg_trans_NIPA PF05653.14 EPS29144.1 - 1e-89 300.6 28.0 1.4e-89 300.1 28.0 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.20 EPS29144.1 - 6.5e-06 26.4 5.9 6.5e-06 26.4 5.9 3.1 3 0 0 3 3 3 1 EamA-like transporter family BRCT_2 PF16589.5 EPS29145.1 - 7.9e-07 29.4 0.0 2.2e-06 28.0 0.0 1.8 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EPS29145.1 - 0.00083 19.7 0.0 0.0019 18.5 0.0 1.6 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF655 PF04919.12 EPS29145.1 - 0.24 11.3 0.0 0.38 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF655) PTCB-BRCT PF12738.7 EPS29145.1 - 0.29 11.1 0.9 0.91 9.5 0.0 2.1 2 0 0 2 2 2 0 twin BRCT domain KilA-N PF04383.13 EPS29146.1 - 0.00032 20.5 0.0 0.0079 16.0 0.0 2.3 1 1 0 1 1 1 1 KilA-N domain HA2 PF04408.23 EPS29148.1 - 1.2e-16 60.9 0.0 3.2e-16 59.5 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EPS29148.1 - 2.7e-14 53.4 0.3 1.2e-13 51.3 0.1 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 EPS29148.1 - 4.5e-11 42.8 0.1 1.2e-10 41.5 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EPS29148.1 - 1.9e-06 28.2 0.1 8.5e-06 26.1 0.1 2.1 1 0 0 1 1 1 1 AAA domain OB_NTP_bind PF07717.16 EPS29148.1 - 1.1e-05 25.7 0.0 2.4e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Gcn1_N PF12074.8 EPS29149.1 - 1.8e-117 392.6 5.0 7e-116 387.4 2.1 3.5 2 0 0 2 2 2 1 Generalcontrol nonderepressible 1 (Gcn1) N-terminal HEAT PF02985.22 EPS29149.1 - 1.3e-31 106.0 31.1 0.095 13.0 0.1 20.4 20 0 0 20 20 19 8 HEAT repeat HEAT_EZ PF13513.6 EPS29149.1 - 3.4e-31 107.3 43.5 7.2e-07 29.6 0.1 19.9 18 5 6 24 24 22 7 HEAT-like repeat HEAT_2 PF13646.6 EPS29149.1 - 1.1e-24 86.6 41.2 4.2e-07 30.3 1.9 14.1 11 4 3 15 15 14 7 HEAT repeats Cnd1 PF12717.7 EPS29149.1 - 4.3e-12 46.4 11.9 0.13 12.3 0.4 9.1 6 3 2 9 9 9 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EPS29149.1 - 7.1e-11 42.6 0.0 5.1 7.8 0.0 8.4 5 2 2 8 8 7 1 Vacuolar 14 Fab1-binding region ParcG PF10274.9 EPS29149.1 - 5.1e-09 36.5 3.7 0.023 14.8 0.0 6.2 5 1 1 6 6 6 2 Parkin co-regulated protein CLASP_N PF12348.8 EPS29149.1 - 4.2e-07 29.8 0.0 0.12 11.9 0.0 5.6 5 1 1 6 6 6 2 CLASP N terminal TIP120 PF08623.10 EPS29149.1 - 9.2e-07 28.8 0.1 0.0011 18.8 0.0 5.3 4 2 1 6 6 5 1 TATA-binding protein interacting (TIP20) IFRD PF05004.13 EPS29149.1 - 0.00043 19.5 21.8 0.28 10.3 3.3 6.1 8 0 0 8 8 8 3 Interferon-related developmental regulator (IFRD) FANCI_S2 PF14676.6 EPS29149.1 - 0.0022 18.3 0.8 0.081 13.2 0.2 3.7 2 1 0 2 2 2 1 FANCI solenoid 2 Tti2 PF10521.9 EPS29149.1 - 0.0042 16.7 0.9 4.4 6.7 0.0 5.4 5 0 0 5 5 5 1 Tti2 family Pes-10 PF07149.11 EPS29149.1 - 0.0052 15.9 0.5 0.018 14.1 0.1 2.0 2 0 0 2 2 2 1 Pes-10 Adaptin_N PF01602.20 EPS29149.1 - 0.0061 15.2 13.4 2.6 6.5 0.5 6.2 4 3 2 6 6 6 2 Adaptin N terminal region mRNA_stabil PF13929.6 EPS29149.1 - 0.01 14.8 0.1 0.036 13.1 0.0 1.9 2 0 0 2 2 2 0 mRNA stabilisation MnmE_helical PF12631.7 EPS29149.1 - 0.032 14.4 0.0 48 4.0 0.0 4.8 5 2 0 5 5 4 0 MnmE helical domain DUF937 PF06078.11 EPS29149.1 - 0.063 13.9 12.7 13 6.4 0.0 6.0 6 1 0 6 6 4 0 Bacterial protein of unknown function (DUF937) ADSL_C PF10397.9 EPS29149.1 - 0.14 12.8 4.1 21 5.8 0.0 5.5 5 0 0 5 5 4 0 Adenylosuccinate lyase C-terminus MMS19_C PF12460.8 EPS29149.1 - 0.23 10.5 19.6 1.6 7.7 0.5 7.3 8 0 0 8 8 8 0 RNAPII transcription regulator C-terminal Arm PF00514.23 EPS29149.1 - 0.51 10.4 12.5 25 5.1 0.0 8.3 9 1 1 10 10 10 0 Armadillo/beta-catenin-like repeat Ribosomal_L19e PF01280.20 EPS29150.1 - 2.5e-61 205.9 8.5 2.5e-61 205.9 8.5 1.6 2 0 0 2 2 2 1 Ribosomal protein L19e TRAP-gamma PF07074.12 EPS29150.1 - 2.2 7.8 3.6 3.2 7.3 3.6 1.2 1 0 0 1 1 1 0 Translocon-associated protein, gamma subunit (TRAP-gamma) Bys1 PF04681.12 EPS29152.1 - 1.4e-10 41.3 0.3 1.7e-10 41.1 0.3 1.1 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Zn_clus PF00172.18 EPS29153.1 - 2.5e-10 40.3 11.2 2.5e-10 40.3 11.2 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YppG PF14179.6 EPS29153.1 - 0.18 12.5 0.1 0.18 12.5 0.1 3.8 3 1 0 3 3 3 0 YppG-like protein TPR_10 PF13374.6 EPS29155.1 - 2.9e-35 119.1 5.3 8.9e-08 31.8 0.1 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 EPS29155.1 - 6.7e-35 119.2 9.0 9.9e-16 57.8 2.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 EPS29155.1 - 6.8e-23 79.5 5.2 0.00025 20.7 0.6 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 EPS29155.1 - 1.7e-18 65.2 4.8 0.0028 17.6 0.6 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 EPS29155.1 - 1.5e-17 62.2 3.5 0.0046 17.1 0.0 5.8 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 EPS29155.1 - 1.2e-15 56.2 7.7 0.0059 16.5 0.0 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_MalT PF17874.1 EPS29155.1 - 1.3e-12 47.8 4.5 2.6e-12 46.8 4.5 1.4 1 0 0 1 1 1 1 MalT-like TPR region TPR_14 PF13428.6 EPS29155.1 - 2e-12 46.8 3.3 0.12 13.3 0.0 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 EPS29155.1 - 4.8e-09 36.7 3.4 0.0027 18.3 0.2 4.7 4 1 0 4 4 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 EPS29155.1 - 1.9e-08 34.1 0.1 3 8.7 0.0 5.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EPS29155.1 - 0.00014 22.3 9.2 0.064 13.8 0.6 4.1 2 1 3 5 5 4 3 Tetratricopeptide repeat DUF3726 PF12525.8 EPS29155.1 - 0.0003 20.8 2.8 4.7 7.4 0.0 4.5 4 0 0 4 4 4 1 Protein of unknown function (DUF3726) NB-ARC PF00931.22 EPS29155.1 - 0.00058 19.1 0.0 0.00087 18.5 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_11 PF13414.6 EPS29155.1 - 0.0006 19.4 5.8 8.5 6.1 0.2 5.6 5 1 1 6 6 6 1 TPR repeat DNApol_Exo PF18136.1 EPS29155.1 - 0.0023 17.1 0.0 0.0039 16.4 0.0 1.3 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain TPR_17 PF13431.6 EPS29155.1 - 0.0042 17.4 4.6 3.5 8.2 0.1 4.9 7 1 0 7 7 4 1 Tetratricopeptide repeat TPR_21 PF09976.9 EPS29155.1 - 0.0093 15.7 4.1 3.6 7.3 0.1 3.7 1 1 3 4 4 4 2 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 EPS29155.1 - 0.52 11.1 8.3 1.4e+02 3.5 0.1 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat AMP-binding PF00501.28 EPS29156.1 - 7.9e-51 173.0 0.1 1.1e-50 172.5 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EPS29156.1 - 1.2e-07 32.6 0.0 2.4e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cys_Met_Meta_PP PF01053.20 EPS29157.1 - 1e-31 109.9 0.0 1.4e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme S-AdoMet_synt_M PF02772.16 EPS29157.1 - 0.14 12.4 0.0 0.3 11.4 0.0 1.5 1 0 0 1 1 1 0 S-adenosylmethionine synthetase, central domain Trp_halogenase PF04820.14 EPS29158.1 - 7.3e-29 100.9 0.0 8.5e-15 54.5 0.0 2.2 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.19 EPS29158.1 - 5e-08 32.6 0.8 5.5e-06 25.9 0.1 2.7 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 EPS29158.1 - 2.4e-06 27.7 0.1 1.5e-05 25.2 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EPS29158.1 - 0.00012 21.6 0.7 0.00024 20.6 0.7 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPS29158.1 - 0.00017 20.9 0.0 0.00024 20.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EPS29158.1 - 0.00083 19.0 1.1 0.002 17.8 0.7 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 EPS29158.1 - 0.0024 17.0 0.0 0.0037 16.4 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EPS29158.1 - 0.0029 16.7 0.3 0.0047 16.1 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EPS29158.1 - 0.0035 16.1 0.2 0.013 14.2 0.2 1.8 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 EPS29158.1 - 0.0097 15.2 0.0 0.66 9.2 0.1 2.4 2 0 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.6 EPS29158.1 - 0.14 12.6 0.0 1.6 9.2 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding Lycopene_cycl PF05834.12 EPS29158.1 - 0.18 10.8 0.1 0.39 9.7 0.1 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein Brr6_like_C_C PF10104.9 EPS29159.1 - 0.024 14.4 0.9 0.2 11.4 0.0 2.1 1 1 1 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain RNase_J_C PF17770.1 EPS29159.1 - 0.16 13.1 0.1 4.3 8.5 0.0 2.1 2 0 0 2 2 2 0 Ribonuclease J C-terminal domain Glyco_hydro_18 PF00704.28 EPS29160.1 - 2.7e-32 112.7 0.8 5.3e-18 65.8 0.2 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 Mid2 PF04478.12 EPS29163.1 - 0.0099 15.7 0.4 0.016 15.1 0.4 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor MLANA PF14991.6 EPS29163.1 - 0.031 14.6 0.1 0.17 12.2 0.0 2.0 2 0 0 2 2 2 0 Protein melan-A Amnionless PF14828.6 EPS29163.1 - 0.064 12.1 0.0 0.086 11.7 0.0 1.1 1 0 0 1 1 1 0 Amnionless adh_short PF00106.25 EPS29164.1 - 2.7e-37 128.1 0.2 3.8e-37 127.6 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS29164.1 - 2.5e-26 92.7 0.0 3.6e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPS29164.1 - 2.6e-07 30.8 3.6 1.4e-05 25.1 3.7 2.7 1 1 1 2 2 2 1 KR domain Epimerase PF01370.21 EPS29164.1 - 0.00011 21.8 0.1 0.00021 20.8 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family LytR_C PF13399.6 EPS29164.1 - 0.0061 17.5 0.2 1.1 10.3 0.0 3.2 2 1 1 3 3 3 1 LytR cell envelope-related transcriptional attenuator 3HCDH_N PF02737.18 EPS29164.1 - 0.029 14.3 0.3 0.19 11.6 0.1 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 EPS29164.1 - 0.09 12.7 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H-binding UPF0146 PF03686.13 EPS29164.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Gly-zipper_Omp PF13488.6 EPS29165.1 - 2.2e-06 27.6 17.9 0.0058 16.6 0.5 5.6 5 0 0 5 5 5 3 Glycine zipper DUF4235 PF14019.6 EPS29165.1 - 0.024 14.7 1.9 43 4.3 0.5 4.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4235) Tim17 PF02466.19 EPS29165.1 - 0.11 12.9 0.8 6.8 7.1 0.0 3.7 4 0 0 4 4 4 0 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_YMGG PF13441.6 EPS29165.1 - 0.33 10.7 29.8 0.067 12.9 2.7 5.0 5 0 0 5 5 5 0 YMGG-like Gly-zipper HIP1_clath_bdg PF16515.5 EPS29168.1 - 0.0028 18.2 9.1 0.0028 18.2 9.1 3.7 4 0 0 4 4 3 1 Clathrin-binding domain of Huntingtin-interacting protein 1 ADIP PF11559.8 EPS29168.1 - 0.0035 17.4 21.4 0.037 14.1 4.7 3.1 1 1 2 3 3 3 2 Afadin- and alpha -actinin-Binding TSC22 PF01166.18 EPS29168.1 - 0.0065 16.8 12.2 0.06 13.7 0.6 3.7 3 0 0 3 3 3 1 TSC-22/dip/bun family bZIP_1 PF00170.21 EPS29168.1 - 0.02 15.0 0.8 0.02 15.0 0.8 3.8 4 0 0 4 4 3 0 bZIP transcription factor Ku_PK_bind PF08785.11 EPS29168.1 - 0.03 14.4 1.9 0.61 10.2 0.1 2.8 1 1 1 2 2 2 0 Ku C terminal domain like FlaC_arch PF05377.11 EPS29168.1 - 0.044 14.2 1.7 0.044 14.2 1.7 3.7 5 0 0 5 5 3 0 Flagella accessory protein C (FlaC) CLZ PF16526.5 EPS29168.1 - 0.062 13.7 0.6 0.062 13.7 0.6 4.1 4 1 0 4 4 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Spidroin_N PF16763.5 EPS29168.1 - 0.083 12.9 5.2 3.3 7.8 0.0 3.4 2 1 1 3 3 3 0 Major ampullate spidroin 1, spider silk protein 1, N-term AKAP95 PF04988.12 EPS29168.1 - 0.11 12.8 0.6 0.24 11.6 0.6 1.5 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) DUF5082 PF16888.5 EPS29168.1 - 0.13 12.6 12.2 0.22 11.8 11.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) MAD PF05557.13 EPS29168.1 - 0.16 10.3 22.3 0.082 11.3 5.5 2.3 1 1 1 2 2 2 0 Mitotic checkpoint protein Bcr-Abl_Oligo PF09036.10 EPS29168.1 - 0.17 11.9 9.2 0.29 11.2 1.3 3.4 3 0 0 3 3 3 0 Bcr-Abl oncoprotein oligomerisation domain AAA_15 PF13175.6 EPS29168.1 - 0.19 11.4 1.0 0.31 10.7 1.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain UPF0242 PF06785.11 EPS29168.1 - 0.19 11.8 22.1 2.9 7.9 22.1 2.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF3584 PF12128.8 EPS29168.1 - 0.35 8.3 25.3 0.52 7.7 25.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_13 PF13166.6 EPS29168.1 - 0.5 9.0 13.7 0.88 8.1 13.7 1.3 1 0 0 1 1 1 0 AAA domain DUF641 PF04859.12 EPS29168.1 - 0.7 10.2 15.2 1.1 9.6 5.7 3.2 1 1 0 2 2 2 0 Plant protein of unknown function (DUF641) Csm1_N PF18504.1 EPS29168.1 - 0.7 10.3 19.5 2 8.8 4.0 4.6 4 1 0 4 4 4 0 Csm1 N-terminal domain TMF_TATA_bd PF12325.8 EPS29168.1 - 0.71 10.1 27.3 0.082 13.1 5.1 3.8 2 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 EPS29168.1 - 0.71 8.7 25.0 0.81 8.5 13.8 2.5 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4446 PF14584.6 EPS29168.1 - 0.83 9.6 8.3 0.27 11.2 1.9 2.7 2 1 1 3 3 2 0 Protein of unknown function (DUF4446) DUF812 PF05667.11 EPS29168.1 - 1.1 8.1 21.6 0.15 10.9 17.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF812) GAS PF13851.6 EPS29168.1 - 1.5 8.2 25.5 0.38 10.1 5.5 3.2 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding NPV_P10 PF05531.12 EPS29168.1 - 1.6 9.3 7.6 21 5.6 0.2 4.0 2 1 2 4 4 3 0 Nucleopolyhedrovirus P10 protein V_ATPase_I PF01496.19 EPS29168.1 - 2 6.2 14.9 2.5 5.9 7.7 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Fib_alpha PF08702.10 EPS29168.1 - 2.3 8.4 17.5 13 6.0 8.9 3.4 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Bap31_Bap29_C PF18035.1 EPS29168.1 - 3 7.9 13.8 1.8 8.7 0.5 3.6 3 0 0 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain DASH_Dam1 PF08653.10 EPS29168.1 - 3.6 7.4 6.0 4.1 7.3 0.1 3.3 3 0 0 3 3 3 0 DASH complex subunit Dam1 DUF1664 PF07889.12 EPS29168.1 - 4.2 7.4 12.8 9.9 6.2 2.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Allexi_40kDa PF05549.11 EPS29168.1 - 5 6.6 7.2 5.7 6.4 4.9 2.2 2 1 0 2 2 2 0 Allexivirus 40kDa protein ApoLp-III PF07464.11 EPS29168.1 - 5.2 7.2 14.5 0.51 10.4 4.1 3.0 2 1 1 3 3 3 0 Apolipophorin-III precursor (apoLp-III) Prominin PF05478.11 EPS29168.1 - 5.3 4.9 8.7 15 3.3 8.7 1.7 1 1 0 1 1 1 0 Prominin IZUMO PF15005.6 EPS29168.1 - 5.7 7.5 9.6 5.2 7.6 3.0 3.1 1 1 3 4 4 3 0 Izumo sperm-egg fusion, Ig domain-associated Baculo_PEP_C PF04513.12 EPS29168.1 - 6 6.9 10.4 1.1 9.3 2.3 2.7 2 1 1 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fez1 PF06818.15 EPS29168.1 - 6.3 7.2 26.9 7.4 7.0 22.6 2.7 2 1 1 3 3 3 0 Fez1 DUF948 PF06103.11 EPS29168.1 - 8.7 6.7 6.3 56 4.1 0.4 3.3 2 1 2 4 4 3 0 Bacterial protein of unknown function (DUF948) Uso1_p115_C PF04871.13 EPS29168.1 - 9.3 6.6 28.5 2.3 8.6 6.3 3.1 2 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region CorA PF01544.18 EPS29169.1 - 2e-39 135.7 0.4 3.9e-39 134.7 0.4 1.4 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Glyco_hydro_2_C PF02836.17 EPS29171.1 - 2.3e-102 342.2 0.7 3e-102 341.8 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 EPS29171.1 - 4.3e-58 196.8 0.0 7.7e-58 196.0 0.0 1.3 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 EPS29171.1 - 4e-42 144.0 0.3 8e-42 143.0 0.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain DUF4981 PF16353.5 EPS29171.1 - 2.4e-21 76.0 0.1 6.4e-21 74.6 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 EPS29171.1 - 2.9e-07 31.2 0.0 9.2e-07 29.5 0.0 2.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_72 PF03198.14 EPS29171.1 - 0.015 14.6 0.3 0.07 12.4 0.1 1.9 1 1 1 2 2 2 0 Glucanosyltransferase Vac7 PF12751.7 EPS29173.1 - 1.9e-159 531.2 0.3 1.9e-159 531.2 0.3 2.2 3 0 0 3 3 3 1 Vacuolar segregation subunit 7 Myb_DNA-bind_5 PF13873.6 EPS29174.1 - 0.095 12.8 0.3 0.14 12.3 0.3 1.3 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF3824 PF12868.7 EPS29175.1 - 2.4e-41 141.9 39.6 2.4e-41 141.9 39.6 8.9 3 1 6 9 9 9 3 Domain of unknwon function (DUF3824) CDH-cyt PF16010.5 EPS29178.1 - 1e-27 97.0 0.3 1e-27 97.0 0.3 1.7 2 0 0 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 EPS29178.1 - 2.9e-08 34.0 11.4 6e-08 32.9 11.4 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.17 EPS29178.1 - 0.00022 21.4 0.6 0.00045 20.4 0.1 1.7 2 0 0 2 2 2 1 DOMON domain DUF2427 PF10348.9 EPS29178.1 - 0.00067 19.4 5.6 0.00067 19.4 5.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) SdpI PF13630.6 EPS29178.1 - 0.0014 18.7 1.6 0.0014 18.7 1.6 2.9 2 1 0 2 2 2 1 SdpI/YhfL protein family DUF4448 PF14610.6 EPS29178.1 - 0.058 13.2 1.0 0.76 9.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) DUF4231 PF14015.6 EPS29178.1 - 0.26 11.8 3.1 1.9 9.0 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) TrbC PF04956.13 EPS29178.1 - 3.6 7.9 19.5 8.4 6.7 6.0 2.6 2 0 0 2 2 2 0 TrbC/VIRB2 family DUF4079 PF13301.6 EPS29178.1 - 4.7 7.4 10.5 12 6.0 6.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) Cu_bind_like PF02298.17 EPS29179.1 - 0.00051 20.0 0.2 0.0017 18.3 0.2 1.8 1 1 0 1 1 1 1 Plastocyanin-like domain Copper-bind PF00127.20 EPS29179.1 - 0.0025 18.2 0.1 0.034 14.6 0.1 2.2 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 EPS29179.1 - 0.02 15.0 0.0 0.12 12.5 0.0 1.9 2 0 0 2 2 2 0 Cupredoxin-like domain NdhS PF11623.8 EPS29179.1 - 0.09 12.5 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 NAD(P)H dehydrogenase subunit S Fungal_trans PF04082.18 EPS29180.1 - 1.7e-12 47.0 0.2 1.7e-12 47.0 0.2 2.3 1 1 2 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS29180.1 - 3.5e-07 30.2 7.1 6.4e-07 29.4 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MTA_R1 PF17226.2 EPS29180.1 - 0.056 13.6 0.3 0.13 12.4 0.3 1.7 1 0 0 1 1 1 0 MTA R1 domain Sugar_tr PF00083.24 EPS29182.1 - 3.2e-74 250.4 28.3 3.8e-74 250.2 28.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS29182.1 - 6.6e-26 91.1 25.3 1.2e-25 90.2 22.7 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Ribosomal_L44 PF00935.19 EPS29183.1 - 3.7e-36 123.4 13.1 6.7e-36 122.6 13.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L44 ubiquitin PF00240.23 EPS29184.1 - 1.1e-25 89.2 0.0 1.2e-25 89.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EPS29184.1 - 1.1e-13 50.8 0.0 1.2e-13 50.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EPS29184.1 - 0.00034 21.0 0.0 0.001 19.4 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EPS29184.1 - 0.012 15.5 0.0 0.014 15.3 0.0 1.1 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain Elongin_A PF06881.11 EPS29185.1 - 7e-27 94.0 0.2 1.1e-26 93.4 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A TBCA PF02970.16 EPS29186.1 - 2.6e-22 78.9 12.2 2.7e-22 78.9 11.6 1.4 1 1 0 1 1 1 1 Tubulin binding cofactor A SidE PF12252.8 EPS29186.1 - 0.0027 15.3 0.5 0.003 15.2 0.5 1.0 1 0 0 1 1 1 1 Dot/Icm substrate protein DUF87 PF01935.17 EPS29186.1 - 0.18 11.9 3.0 0.21 11.7 3.0 1.0 1 0 0 1 1 1 0 Helicase HerA, central domain Ribosomal_L29 PF00831.23 EPS29186.1 - 0.3 11.1 9.8 0.2 11.6 5.9 2.3 1 1 2 3 3 3 0 Ribosomal L29 protein DUF4404 PF14357.6 EPS29186.1 - 0.49 11.1 6.8 0.11 13.2 2.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) DUF2570 PF10828.8 EPS29186.1 - 0.84 9.5 6.5 0.83 9.5 5.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) HSP70 PF00012.20 EPS29186.1 - 3.4 5.7 10.5 3.9 5.5 10.5 1.0 1 0 0 1 1 1 0 Hsp70 protein THOC7 PF05615.13 EPS29187.1 - 5.4e-45 152.9 2.6 5.4e-45 152.9 2.6 2.1 1 1 1 2 2 2 1 Tho complex subunit 7 Mod_r PF07200.13 EPS29187.1 - 0.00062 19.9 9.2 0.0011 19.1 9.2 1.4 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Peroxin-13_N PF04088.13 EPS29187.1 - 0.054 13.8 0.1 0.094 13.0 0.1 1.5 1 0 0 1 1 1 0 Peroxin 13, N-terminal region FUSC PF04632.12 EPS29187.1 - 0.12 10.9 6.5 0.16 10.5 6.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family PilJ PF13675.6 EPS29187.1 - 0.29 11.2 5.9 0.44 10.6 4.9 1.9 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term APH PF01636.23 EPS29188.1 - 2.3e-08 34.3 0.1 4.2e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EPS29188.1 - 0.0011 18.3 0.1 0.022 14.1 0.0 2.2 2 0 0 2 2 2 1 Ecdysteroid kinase DUF1679 PF07914.11 EPS29188.1 - 0.018 13.9 0.0 0.052 12.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) MFS_1 PF07690.16 EPS29189.1 - 1.3e-47 162.4 39.4 1.5e-45 155.7 41.5 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EPS29189.1 - 2e-15 56.3 19.6 2.6e-15 55.9 19.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EPS29189.1 - 5.1e-09 35.5 14.5 5.1e-09 35.5 14.5 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter MRI PF15325.6 EPS29189.1 - 0.1 13.7 0.1 0.24 12.5 0.1 1.5 1 0 0 1 1 1 0 Modulator of retrovirus infection Fungal_trans PF04082.18 EPS29190.1 - 1.4e-30 106.3 0.6 2.2e-30 105.6 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS29190.1 - 2.6e-08 33.8 11.6 5e-08 32.9 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugarporin_N PF11471.8 EPS29190.1 - 0.011 15.7 1.8 0.03 14.3 1.8 1.7 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Iron_permease PF04120.12 EPS29191.1 - 1.6e-30 105.5 8.2 2.4e-14 53.2 0.0 3.4 3 0 0 3 3 3 3 Low affinity iron permease NicO PF03824.16 EPS29191.1 - 0.0003 20.2 0.6 0.0003 20.2 0.6 2.0 2 0 0 2 2 2 1 High-affinity nickel-transport protein EOS1 PF12326.8 EPS29191.1 - 0.092 12.7 1.8 0.29 11.0 0.1 2.2 2 0 0 2 2 2 0 N-glycosylation protein FAM167 PF11652.8 EPS29191.1 - 0.096 13.2 0.6 0.24 11.9 0.6 1.6 1 0 0 1 1 1 0 FAM167 HU-DNA_bdg PF14848.6 EPS29191.1 - 0.17 11.9 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 DNA-binding domain Oxidored_FMN PF00724.20 EPS29192.1 - 1.8e-42 145.9 0.0 3.1e-42 145.1 0.0 1.4 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Malic_M PF03949.15 EPS29193.1 - 3.2e-91 305.2 0.0 4.2e-91 304.8 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EPS29193.1 - 5.6e-63 212.0 0.0 9.8e-63 211.2 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF4449 PF14613.6 EPS29195.1 - 6e-07 29.7 1.0 6e-07 29.7 1.0 4.0 4 1 0 4 4 4 1 Protein of unknown function (DUF4449) Tricorn_C1 PF14684.6 EPS29195.1 - 0.0012 18.8 0.4 0.032 14.3 0.2 3.1 3 0 0 3 3 3 1 Tricorn protease C1 domain Casein PF00363.18 EPS29195.1 - 0.083 13.3 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 Casein PilO PF04350.13 EPS29195.1 - 0.23 11.6 1.6 1.4 9.1 0.7 2.5 2 0 0 2 2 2 0 Pilus assembly protein, PilO TPR_6 PF13174.6 EPS29195.1 - 0.28 11.9 3.1 0.58 10.9 0.1 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat SbsC_C PF18058.1 EPS29195.1 - 5.4 7.3 11.5 0.22 11.8 3.4 2.8 2 1 0 2 2 2 0 SbsC C-terminal domain DnaJ_C PF01556.18 EPS29196.1 - 3.2e-25 88.9 0.0 4.5e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EPS29196.1 - 4.8e-25 87.5 1.3 8.4e-25 86.7 1.3 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EPS29196.1 - 2.7e-15 56.5 14.7 4.2e-15 55.8 14.7 1.3 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EPS29196.1 - 3.6e-06 26.8 5.8 0.023 14.7 0.3 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein Lar_restr_allev PF14354.6 EPS29196.1 - 0.017 15.5 10.6 0.41 11.1 0.1 3.5 1 1 2 3 3 3 0 Restriction alleviation protein Lar HypA PF01155.19 EPS29196.1 - 0.02 14.9 8.0 1.1 9.3 0.7 2.2 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 EPS29196.1 - 0.071 12.8 7.1 0.97 9.1 0.3 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 zinc-ribbons_6 PF07191.12 EPS29196.1 - 6.2 6.9 10.8 2e+02 2.0 10.8 2.2 1 1 0 1 1 1 0 zinc-ribbons Ribosomal_S4 PF00163.19 EPS29197.1 - 1.8e-08 35.2 0.6 3.3e-08 34.3 0.6 1.6 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 EPS29197.1 - 1.9e-05 24.3 0.3 3.3e-05 23.5 0.3 1.4 1 0 0 1 1 1 1 S4 domain Alk_phosphatase PF00245.20 EPS29198.1 - 1.1e-68 232.1 0.6 2.7e-68 230.8 0.6 1.6 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.23 EPS29198.1 - 1.7e-07 30.9 0.5 3.2e-07 30.1 0.5 1.7 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EPS29198.1 - 1.8e-05 24.5 0.1 3.9e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 EPS29198.1 - 0.00044 19.0 0.3 0.00072 18.3 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.18 EPS29198.1 - 0.0017 17.8 0.2 0.0038 16.6 0.2 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF1501 PF07394.12 EPS29198.1 - 0.0066 15.5 0.1 0.011 14.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) Sugar_tr PF00083.24 EPS29201.1 - 3.9e-88 296.3 15.9 4.4e-88 296.1 15.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS29201.1 - 4.2e-17 62.1 55.0 4.4e-14 52.2 29.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EPS29201.1 - 1.4e-07 30.5 14.6 3.8e-05 22.4 4.4 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 EPS29201.1 - 0.12 11.3 16.5 0.057 12.3 5.6 2.2 2 0 0 2 2 2 0 MFS_1 like family DUF373 PF04123.13 EPS29201.1 - 6.5 6.1 6.5 0.66 9.4 1.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Alpha-amylase PF00128.24 EPS29202.1 - 8.4e-111 370.8 0.0 1.1e-110 370.4 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF3459 PF11941.8 EPS29202.1 - 2.6e-05 24.4 0.0 7.3e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3459) Alpha-amylase_C PF02806.18 EPS29202.1 - 0.0019 18.6 0.0 0.0063 17.0 0.0 1.9 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Malt_amylase_C PF16657.5 EPS29202.1 - 0.0021 18.1 0.0 0.024 14.8 0.0 2.7 3 0 0 3 3 3 1 Maltogenic Amylase, C-terminal domain Glyco_hydro_42C PF08533.10 EPS29202.1 - 0.0087 15.8 0.0 0.033 13.9 0.0 2.0 1 0 0 1 1 1 1 Beta-galactosidase C-terminal domain hDGE_amylase PF14701.6 EPS29202.1 - 0.011 14.8 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Zn_clus PF00172.18 EPS29203.1 - 8.4e-07 29.0 9.9 1.5e-06 28.3 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPS29203.1 - 0.0016 17.5 0.1 0.0027 16.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain LamB PF02264.15 EPS29204.1 - 0.19 11.6 0.0 0.2 11.5 0.0 1.0 1 0 0 1 1 1 0 LamB porin Glyco_hydro_114 PF03537.13 EPS29205.1 - 2.4e-82 275.7 5.2 5.7e-80 268.0 3.1 2.2 2 0 0 2 2 2 2 Glycoside-hydrolase family GH114 Hydrolase_6 PF13344.6 EPS29207.1 - 3.3e-22 78.5 0.0 6.6e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EPS29207.1 - 1.3e-18 66.9 0.0 2.8e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 EPS29207.1 - 0.07 13.2 0.0 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Gly_transf_sug PF04488.15 EPS29208.1 - 3.8e-08 33.9 0.0 8.3e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Virul_Fac PF10139.9 EPS29208.1 - 0.0031 15.8 0.0 0.0044 15.3 0.0 1.1 1 0 0 1 1 1 1 Putative bacterial virulence factor CAP59_mtransfer PF11735.8 EPS29209.1 - 3.4e-72 243.0 0.0 4.2e-72 242.7 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 PIG-L PF02585.17 EPS29210.1 - 1.1e-22 81.1 0.0 1.5e-22 80.6 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Gly_transf_sug PF04488.15 EPS29211.1 - 1.6e-11 44.7 0.0 3.7e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Nuc_sug_transp PF04142.15 EPS29212.1 - 7.5e-27 94.3 8.7 9.7e-27 94.0 8.7 1.0 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 EPS29212.1 - 4.4e-08 32.7 7.0 3.6e-07 29.7 4.8 2.3 1 1 1 2 2 2 1 UAA transporter family EamA PF00892.20 EPS29212.1 - 3.2e-06 27.4 20.4 0.0035 17.5 3.4 2.5 2 1 1 3 3 3 2 EamA-like transporter family PUNUT PF16913.5 EPS29212.1 - 7.5e-05 22.1 6.1 7.5e-05 22.1 6.1 1.4 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport EmrE PF13536.6 EPS29212.1 - 0.00019 21.1 10.9 0.00027 20.6 0.5 2.7 2 1 0 3 3 3 2 Putative multidrug resistance efflux transporter Glyco_hydro_28 PF00295.17 EPS29213.1 - 2.3e-104 349.0 22.6 2.9e-104 348.6 22.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 MFS_1 PF07690.16 EPS29216.1 - 1.3e-38 132.8 27.5 9e-38 130.1 25.7 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily FtsX PF02687.21 EPS29216.1 - 0.011 16.2 0.4 0.011 16.2 0.4 3.9 1 1 0 2 2 2 0 FtsX-like permease family Saf_2TM PF18303.1 EPS29216.1 - 0.032 13.8 0.3 6.2 6.4 0.1 2.7 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain Chitin_synth_1 PF01644.17 EPS29216.1 - 0.084 12.8 0.1 14 5.6 0.0 2.2 2 0 0 2 2 2 0 Chitin synthase DUF4381 PF14316.6 EPS29216.1 - 0.4 10.9 2.7 0.66 10.2 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Anoctamin PF04547.12 EPS29216.1 - 0.57 9.0 8.0 0.39 9.5 0.1 2.7 2 1 1 3 3 3 0 Calcium-activated chloride channel DUF1201 PF06716.11 EPS29216.1 - 8.1 6.6 8.7 0.17 11.9 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) OMPdecase PF00215.24 EPS29217.1 - 9.6e-78 260.8 0.0 1.1e-77 260.6 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family MAPEG PF01124.18 EPS29218.1 - 2.3e-26 92.2 0.7 2.6e-26 92.0 0.7 1.0 1 0 0 1 1 1 1 MAPEG family MBOAT PF03062.19 EPS29219.1 - 3.4e-24 85.9 16.4 7e-24 84.8 16.4 1.5 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 EPS29219.1 - 0.0034 17.6 3.5 0.012 15.9 3.5 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family WD40 PF00400.32 EPS29220.1 - 2e-29 101.2 29.0 1.6e-06 28.8 3.9 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS29220.1 - 7.2e-17 61.5 0.2 0.01 16.1 0.0 5.8 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EPS29220.1 - 0.0022 17.9 0.1 0.59 10.0 0.1 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Bacteroid_pep PF14406.6 EPS29220.1 - 0.094 13.1 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Bacteroidetes Tmemb_170 PF10190.9 EPS29221.1 - 2.8e-22 79.1 11.1 3.2e-22 78.9 11.1 1.0 1 0 0 1 1 1 1 Putative transmembrane protein 170 ICMT PF04140.14 EPS29223.1 - 4.5e-27 94.3 0.1 8.6e-27 93.4 0.1 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EPS29223.1 - 5.4e-11 42.8 1.9 5.4e-11 42.8 1.9 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 EPS29223.1 - 3.8e-05 23.3 0.5 5.1e-05 22.9 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Hexapep_2 PF14602.6 EPS29225.1 - 5.4e-12 45.2 4.6 3.9e-09 36.1 1.1 2.8 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 EPS29225.1 - 6.4e-12 44.7 5.2 4.4e-10 38.9 1.8 3.1 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Mac PF12464.8 EPS29225.1 - 6.6e-07 29.5 0.0 1.1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase DUF3517 PF12030.8 EPS29226.1 - 2.3e-97 326.0 0.0 6.8e-97 324.4 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3517) UCH PF00443.29 EPS29226.1 - 5.2e-41 140.8 0.1 1.9e-40 139.0 0.1 2.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EPS29226.1 - 4.9e-24 85.5 0.1 1e-23 84.5 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TRAPP PF04051.16 EPS29226.1 - 0.012 15.3 0.0 0.042 13.6 0.0 1.9 1 0 0 1 1 1 0 Transport protein particle (TRAPP) component TFIIE_alpha PF02002.17 EPS29228.1 - 9.6e-18 64.0 0.0 2.3e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.12 EPS29228.1 - 0.0069 15.9 1.2 0.018 14.6 1.2 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.11 EPS29228.1 - 0.088 12.7 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF2981 PF11200.8 EPS29228.1 - 0.32 10.7 5.8 0.48 10.1 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Zn-ribbon_8 PF09723.10 EPS29228.1 - 0.64 10.2 2.8 7 6.9 0.2 2.4 1 1 2 3 3 3 0 Zinc ribbon domain PseudoU_synth_1 PF01416.20 EPS29229.1 - 3.9e-11 43.4 0.0 1.8e-09 38.0 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase 2OG-FeII_Oxy_3 PF13640.6 EPS29230.1 - 6.4e-10 39.8 0.0 1.1e-09 39.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cutinase PF01083.22 EPS29233.1 - 9.4e-54 182.1 4.7 1.1e-53 181.9 4.7 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.11 EPS29233.1 - 6e-06 26.0 0.1 8.3e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 PE-PPE domain Hydrolase_4 PF12146.8 EPS29233.1 - 0.08 12.2 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 MFS_1 PF07690.16 EPS29235.1 - 5.5e-16 58.4 52.4 6.2e-09 35.2 17.7 3.0 1 1 2 3 3 3 2 Major Facilitator Superfamily Pox_A14 PF05767.12 EPS29235.1 - 1.2 9.3 5.9 0.89 9.7 0.3 3.1 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 Cupin_2 PF07883.11 EPS29236.1 - 2.8e-11 43.0 0.1 4.7e-11 42.2 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 EPS29236.1 - 6.8e-06 25.8 0.0 1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Cupin MannoseP_isomer PF01050.18 EPS29236.1 - 7e-06 26.0 0.0 1e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase EutQ PF06249.12 EPS29236.1 - 0.0015 18.3 0.0 0.0027 17.5 0.0 1.4 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ AraC_binding PF02311.19 EPS29236.1 - 0.0034 17.3 0.0 0.0052 16.7 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.12 EPS29236.1 - 0.025 14.2 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) DMSP_lyase PF16867.5 EPS29236.1 - 0.096 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase MIIP PF15734.5 EPS29236.1 - 0.19 11.2 0.1 0.27 10.7 0.1 1.1 1 0 0 1 1 1 0 Migration and invasion-inhibitory Nitroreductase PF00881.24 EPS29237.1 - 8.6e-16 58.5 0.0 1e-15 58.2 0.0 1.0 1 0 0 1 1 1 1 Nitroreductase family DUF4253 PF14062.6 EPS29237.1 - 0.031 14.4 0.0 0.051 13.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4253) Cation_ATPase_C PF00689.21 EPS29238.1 - 1.1e-42 145.8 3.5 1.1e-42 145.8 3.5 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EPS29238.1 - 4.3e-37 127.4 3.6 1.1e-36 126.1 2.1 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 EPS29238.1 - 6.4e-23 80.7 0.0 1.2e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EPS29238.1 - 1.2e-18 68.2 0.2 1.7e-08 35.0 0.1 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EPS29238.1 - 5.4e-08 32.4 0.0 1.2e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EPS29238.1 - 0.0013 18.6 0.2 0.0025 17.6 0.2 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PRRSV_2b PF07069.11 EPS29238.1 - 0.0051 17.3 1.0 0.018 15.5 1.0 1.9 1 0 0 1 1 1 1 Porcine reproductive and respiratory syndrome virus 2b HAD PF12710.7 EPS29238.1 - 0.075 13.4 0.0 9.3 6.6 0.0 2.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase TrkH PF02386.16 EPS29239.1 - 3.2e-108 362.4 5.3 1.1e-104 350.7 1.8 2.0 2 0 0 2 2 2 2 Cation transport protein LepB_GAP_C PF18227.1 EPS29239.1 - 0.013 16.0 0.0 10 6.7 0.0 2.5 2 0 0 2 2 2 0 LepB GAP domain C-terminal subdomain Chitin_bind_1 PF00187.19 EPS29240.1 - 1.8e-05 25.1 16.9 1.8e-05 25.1 16.9 3.0 2 1 0 2 2 2 1 Chitin recognition protein LysM PF01476.20 EPS29240.1 - 0.00054 20.0 0.0 0.00091 19.2 0.0 1.3 1 0 0 1 1 1 1 LysM domain fn3_PAP PF17808.1 EPS29240.1 - 0.08 13.1 0.1 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 Fn3-like domain from Purple Acid Phosphatase zf-MYND PF01753.18 EPS29241.1 - 4.3e-09 36.3 18.2 8.2e-09 35.4 18.2 1.5 1 0 0 1 1 1 1 MYND finger SoxD PF04267.12 EPS29241.1 - 0.012 15.7 0.1 0.034 14.3 0.0 1.8 2 0 0 2 2 2 0 Sarcosine oxidase, delta subunit family zf-C6H2 PF15801.5 EPS29241.1 - 0.32 11.3 15.2 0.64 10.4 15.2 1.5 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding DEAD PF00270.29 EPS29242.1 - 5.7e-32 110.9 0.0 9.8e-32 110.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPS29242.1 - 2.3e-18 66.6 0.2 8e-17 61.6 0.4 2.8 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPS29242.1 - 4.1e-07 30.1 0.0 2.8e-06 27.4 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PH PF00169.29 EPS29243.1 - 1.6e-07 31.8 0.0 5.6e-07 30.0 0.0 2.0 1 1 0 1 1 1 1 PH domain Anillin PF08174.11 EPS29243.1 - 3.8e-07 30.6 0.0 8.5e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Cell division protein anillin Transketolase_N PF00456.21 EPS29244.1 - 6.3e-18 64.8 1.8 1.6e-16 60.2 1.9 2.1 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.20 EPS29244.1 - 3.4e-13 49.6 0.0 1.2e-12 47.8 0.0 2.0 3 0 0 3 3 3 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.21 EPS29244.1 - 3.3e-06 27.0 1.4 1.3e-05 25.0 1.4 1.9 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transket_pyr PF02779.24 EPS29244.1 - 0.00014 21.6 0.2 0.00014 21.6 0.2 2.0 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 EPS29244.1 - 0.028 13.4 0.0 0.054 12.4 0.0 1.4 1 0 0 1 1 1 0 Dehydrogenase E1 component PFOR_II PF17147.4 EPS29244.1 - 0.075 13.3 0.0 0.24 11.7 0.0 1.9 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II COesterase PF00135.28 EPS29246.1 - 1.6e-70 238.5 0.0 1.9e-70 238.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EPS29246.1 - 5.1e-05 23.2 0.1 0.0027 17.6 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EPS29246.1 - 0.033 13.6 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family SET PF00856.28 EPS29247.1 - 2e-10 41.3 1.0 4.8e-09 36.8 0.0 2.9 2 2 0 3 3 3 1 SET domain Ribosomal_L14 PF00238.19 EPS29248.1 - 1.4e-45 154.3 3.5 1.6e-45 154.2 3.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Phage_antitermQ PF06530.12 EPS29248.1 - 0.052 13.5 0.1 0.12 12.3 0.1 1.7 1 1 0 1 1 1 0 Phage antitermination protein Q TFIIS_C PF01096.18 EPS29249.1 - 1.2e-14 53.9 1.3 1.2e-14 53.9 1.3 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EPS29249.1 - 4.4e-11 42.5 0.8 4.4e-11 42.5 0.8 3.1 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit GFA PF04828.14 EPS29249.1 - 0.037 14.4 9.2 2.2 8.7 0.0 2.6 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Lar_restr_allev PF14354.6 EPS29249.1 - 0.054 13.9 2.5 0.054 13.9 2.5 2.3 2 1 0 2 2 2 0 Restriction alleviation protein Lar DZR PF12773.7 EPS29249.1 - 0.24 11.4 13.1 4.7e+02 0.9 13.1 2.7 1 1 0 1 1 1 0 Double zinc ribbon zf-CHY PF05495.12 EPS29249.1 - 0.69 10.4 10.5 0.27 11.8 5.7 2.5 1 1 1 2 2 2 0 CHY zinc finger DUF3268 PF11672.8 EPS29249.1 - 1.7 9.0 6.8 1.5 9.1 2.1 2.2 2 0 0 2 2 2 0 zinc-finger-containing domain Rpr2 PF04032.16 EPS29249.1 - 2.3 8.5 9.4 1.4e+02 2.9 9.4 3.1 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain eIF3g PF12353.8 EPS29249.1 - 6.2 7.2 7.7 0.65 10.4 2.7 1.9 2 1 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Rotamase PF00639.21 EPS29250.1 - 1.6e-23 83.5 0.1 2.2e-23 83.0 0.1 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 EPS29250.1 - 1.3e-16 61.1 0.0 1.8e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 EPS29250.1 - 5.3e-10 39.2 1.6 5.3e-10 39.2 1.6 1.8 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.6 EPS29250.1 - 2.7e-05 25.0 0.0 3.5e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain TACC_C PF05010.14 EPS29253.1 - 0.085 12.6 0.6 0.21 11.3 0.6 1.7 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Seryl_tRNA_N PF02403.22 EPS29253.1 - 0.81 9.9 3.9 7.4 6.9 1.8 3.0 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF948 PF06103.11 EPS29253.1 - 0.98 9.7 2.8 2.3 8.5 0.0 2.8 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) RRM_1 PF00076.22 EPS29254.1 - 2.4e-16 59.3 0.0 3.3e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SNO PF01174.19 EPS29255.1 - 2.6e-52 177.4 0.0 1.3e-42 145.8 0.0 2.0 1 1 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 EPS29255.1 - 6.4e-10 39.0 0.0 3.2e-08 33.4 0.0 2.2 2 1 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 EPS29255.1 - 0.0014 18.4 0.0 0.02 14.7 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_S51 PF03575.17 EPS29255.1 - 0.0047 16.6 0.0 0.0068 16.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.24 EPS29255.1 - 0.0095 15.8 0.0 0.026 14.3 0.0 1.6 2 0 0 2 2 2 1 DJ-1/PfpI family GATase_5 PF13507.6 EPS29255.1 - 0.13 11.3 0.0 7 5.7 0.0 2.2 2 0 0 2 2 2 0 CobB/CobQ-like glutamine amidotransferase domain ACPS PF01648.20 EPS29256.1 - 3.6e-12 46.4 0.0 1.6e-11 44.3 0.0 2.2 2 1 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Acyltransferase PF01553.21 EPS29257.1 - 8.1e-34 116.1 0.0 1.4e-33 115.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Phage_holin_3_6 PF07332.11 EPS29257.1 - 2.2 8.4 6.5 4.4 7.4 6.5 1.5 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III TPR_1 PF00515.28 EPS29258.1 - 6.9e-43 142.8 11.9 4.6e-08 32.6 0.0 8.2 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_2 PF07719.17 EPS29258.1 - 2.8e-37 123.8 17.5 7.8e-05 22.5 0.0 9.9 10 0 0 10 10 9 7 Tetratricopeptide repeat ANAPC3 PF12895.7 EPS29258.1 - 6.4e-28 96.8 18.9 1.2e-19 70.3 0.5 4.1 5 0 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 EPS29258.1 - 1.4e-27 93.6 4.9 0.00024 21.0 0.0 9.3 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_11 PF13414.6 EPS29258.1 - 1.2e-25 88.8 4.4 9.7e-06 25.2 1.9 9.8 7 3 3 10 10 10 5 TPR repeat TPR_19 PF14559.6 EPS29258.1 - 9.2e-19 67.7 14.2 2.5e-07 31.1 0.1 7.9 8 1 0 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 EPS29258.1 - 3e-16 59.8 13.2 0.00025 21.6 0.1 8.2 6 2 2 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 EPS29258.1 - 3.7e-16 58.5 13.4 0.091 13.6 0.0 9.6 8 2 2 10 10 9 4 Tetratricopeptide repeat TPR_7 PF13176.6 EPS29258.1 - 7e-16 57.0 0.7 0.013 15.5 0.0 7.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 EPS29258.1 - 7e-15 55.1 16.2 0.0053 17.0 0.0 8.0 5 3 4 9 9 8 6 Tetratricopeptide repeat TPR_17 PF13431.6 EPS29258.1 - 1.7e-09 37.4 16.0 0.26 11.7 0.0 9.1 9 1 1 10 10 10 3 Tetratricopeptide repeat TPR_9 PF13371.6 EPS29258.1 - 1e-06 28.8 3.0 0.053 13.7 0.1 4.9 4 2 2 6 6 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 EPS29258.1 - 0.00025 21.5 12.0 9.7 7.1 0.2 8.7 10 0 0 10 10 9 0 Tetratricopeptide repeat Sel1 PF08238.12 EPS29258.1 - 0.00034 21.2 0.0 15 6.4 0.0 5.1 4 0 0 4 4 4 0 Sel1 repeat TPR_15 PF13429.6 EPS29258.1 - 0.00095 18.5 0.3 1.4 8.1 0.1 3.5 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 EPS29258.1 - 0.002 17.9 1.3 89 3.2 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF5113 PF17140.4 EPS29258.1 - 0.1 12.4 0.5 0.33 10.8 0.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF5113) ChAPs PF09295.10 EPS29258.1 - 0.23 10.4 0.6 17 4.3 0.1 2.5 1 1 2 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF2225 PF09986.9 EPS29258.1 - 1 9.0 4.4 9.7 5.9 0.0 3.2 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) TMEM208_SND2 PF05620.11 EPS29259.1 - 1e-54 184.8 0.0 1.2e-54 184.6 0.0 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 Glyco_tran_WecB PF03808.13 EPS29260.1 - 0.00022 21.2 2.4 2.7 7.9 0.0 4.6 2 1 1 4 4 4 1 Glycosyl transferase WecB/TagA/CpsF family Apolipoprotein PF01442.18 EPS29260.1 - 0.087 12.7 33.0 1.1 9.1 7.9 6.9 4 2 3 7 7 7 0 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 EPS29260.1 - 1.4 9.0 21.3 7.5 6.6 0.1 5.7 5 0 0 5 5 5 0 Apolipophorin-III precursor (apoLp-III) CorA PF01544.18 EPS29260.1 - 2 7.7 3.5 2.8 7.2 0.3 2.7 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein PrmC_N PF17827.1 EPS29260.1 - 7.9 7.1 11.6 2.5 8.8 0.1 4.1 4 0 0 4 4 4 0 PrmC N-terminal domain MHB PF16525.5 EPS29260.1 - 9.8 6.5 11.8 4.2 7.7 0.5 4.0 3 0 0 3 3 3 0 Haemophore, haem-binding RINGv PF12906.7 EPS29261.1 - 8.4e-17 61.0 9.9 1.4e-16 60.3 9.9 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 EPS29261.1 - 0.09 13.1 9.5 0.16 12.3 9.5 1.4 1 0 0 1 1 1 0 Ring finger domain DnaJ_CXXCXGXG PF00684.19 EPS29261.1 - 1.1 9.7 2.9 2.3 8.6 2.9 1.5 1 0 0 1 1 1 0 DnaJ central domain zf-ANAPC11 PF12861.7 EPS29261.1 - 1.1 9.3 3.8 2.3 8.3 3.8 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 EPS29261.1 - 1.5 9.0 6.0 2.9 8.1 6.0 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.6 EPS29261.1 - 2.9 7.8 6.2 4.9 7.0 6.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF3742 PF12553.8 EPS29261.1 - 3 8.0 6.1 0.75 9.9 1.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3742) HeLo PF14479.6 EPS29262.1 - 0.0024 17.7 0.9 0.17 11.7 0.9 2.3 1 1 0 1 1 1 1 Prion-inhibition and propagation Mur_ligase_M PF08245.12 EPS29263.1 - 5.8e-07 29.7 0.4 1.4e-06 28.4 0.4 1.4 1 1 0 1 1 1 1 Mur ligase middle domain Gp_dh_N PF00044.24 EPS29263.1 - 0.12 12.7 0.0 2.9 8.3 0.0 2.3 1 1 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain RNase_T PF00929.24 EPS29264.1 - 4.2e-18 66.4 0.0 3.3e-17 63.5 0.0 2.1 1 1 0 1 1 1 1 Exonuclease HATPase_c PF02518.26 EPS29265.1 - 3.1e-24 85.6 0.0 1.7e-23 83.3 0.0 2.1 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EPS29265.1 - 3.6e-24 85.1 1.4 9.5e-24 83.7 0.5 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 EPS29265.1 - 4.7e-15 55.4 0.0 2.1e-14 53.3 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 EPS29265.1 - 0.0002 21.7 1.4 0.094 13.1 0.0 2.6 2 0 0 2 2 2 2 HAMP domain CMD PF02627.20 EPS29267.1 - 1.8e-11 43.9 0.2 5.3e-09 36.0 0.1 2.3 1 1 0 2 2 2 2 Carboxymuconolactone decarboxylase family ThiF PF00899.21 EPS29268.1 - 5.6e-59 199.5 0.0 7.8e-59 199.0 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 EPS29268.1 - 2.9e-07 31.0 0.0 1.5e-06 28.7 0.0 2.3 3 0 0 3 3 3 1 Rhodanese-like domain ADIP PF11559.8 EPS29268.1 - 0.012 15.7 1.1 0.02 15.0 1.1 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Shikimate_DH PF01488.20 EPS29268.1 - 0.047 13.8 0.0 0.18 11.8 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase MRVI1 PF05781.12 EPS29268.1 - 0.11 11.1 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 MRVI1 protein NAD_binding_7 PF13241.6 EPS29268.1 - 0.14 12.6 0.0 0.38 11.2 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding SlyX PF04102.12 EPS29268.1 - 0.48 11.1 2.5 1.1 10.0 2.5 1.6 1 0 0 1 1 1 0 SlyX adh_short_C2 PF13561.6 EPS29269.1 - 2.3e-59 200.8 0.2 2.6e-59 200.6 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPS29269.1 - 1.3e-39 135.7 0.1 1.7e-39 135.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPS29269.1 - 1.9e-09 37.7 0.7 2.9e-09 37.1 0.7 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EPS29269.1 - 0.00019 21.4 0.1 0.00036 20.5 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 EPS29269.1 - 0.00099 19.8 0.0 0.0021 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain THF_DHG_CYH_C PF02882.19 EPS29269.1 - 0.0044 16.4 0.2 0.012 14.9 0.0 1.8 1 1 1 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ADH_zinc_N PF00107.26 EPS29269.1 - 0.0096 15.9 0.1 0.041 13.9 0.0 1.9 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Epimerase PF01370.21 EPS29269.1 - 0.011 15.2 0.1 0.016 14.7 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EPS29269.1 - 0.012 14.7 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EPS29269.1 - 0.017 15.0 2.7 0.031 14.2 0.7 2.2 2 1 0 2 2 2 0 NAD(P)H-binding RmlD_sub_bind PF04321.17 EPS29269.1 - 0.032 13.3 0.8 0.22 10.6 0.2 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain 3Beta_HSD PF01073.19 EPS29269.1 - 0.055 12.5 0.1 0.12 11.4 0.1 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Gln-synt_C PF00120.24 EPS29270.1 - 3e-80 269.8 0.0 3.7e-80 269.5 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain PALP PF00291.25 EPS29271.1 - 7e-68 229.2 0.1 8.2e-68 229.0 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF836 PF05768.14 EPS29272.1 - 2.6e-12 47.0 0.1 3.1e-12 46.7 0.1 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 EPS29272.1 - 0.082 13.1 0.1 0.11 12.7 0.1 1.5 1 1 0 1 1 1 0 Glutaredoxin Lipase_3 PF01764.25 EPS29273.1 - 2.1e-08 34.1 0.0 6.6e-08 32.5 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) Hydrolase_4 PF12146.8 EPS29273.1 - 0.0049 16.2 0.0 0.0087 15.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EPS29273.1 - 0.021 14.5 0.0 0.066 12.9 0.0 1.8 1 1 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.7 EPS29273.1 - 0.04 14.5 0.4 0.1 13.2 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family UPF0227 PF05728.12 EPS29273.1 - 0.085 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF2974 PF11187.8 EPS29273.1 - 0.17 11.5 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.7 EPS29273.1 - 0.22 11.3 0.0 0.4 10.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF4129 PF13559.6 EPS29274.1 - 0.00024 21.3 0.0 0.00076 19.7 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) NICE-3 PF07406.11 EPS29274.1 - 0.0032 17.5 0.0 0.022 14.7 0.0 1.9 2 0 0 2 2 2 1 NICE-3 protein NAD_binding_1 PF00175.21 EPS29275.1 - 5.4e-07 30.2 0.0 1.4e-06 28.9 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Putative_PNPOx PF01243.20 EPS29275.1 - 1e-05 25.6 0.0 0.048 13.9 0.0 3.3 3 0 0 3 3 3 2 Pyridoxamine 5'-phosphate oxidase NAD_binding_6 PF08030.12 EPS29275.1 - 0.00016 21.8 0.0 0.0027 17.8 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 EPS29275.1 - 0.039 14.3 0.0 1.5 9.2 0.0 2.4 1 1 0 1 1 1 0 Oxidoreductase FAD-binding domain Fungal_trans_2 PF11951.8 EPS29276.1 - 3e-05 23.0 3.9 0.00022 20.2 3.9 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain TPR_12 PF13424.6 EPS29277.1 - 2.6e-06 27.6 1.4 2.6e-06 27.6 1.4 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EPS29277.1 - 2.2e-05 24.1 4.2 0.062 13.2 0.0 3.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EPS29277.1 - 0.00012 21.9 0.7 0.63 10.3 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EPS29277.1 - 0.0013 18.6 0.0 0.38 10.9 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF4407 PF14362.6 EPS29277.1 - 0.0032 16.9 4.8 0.0043 16.4 4.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) SLATT_5 PF18160.1 EPS29277.1 - 0.12 11.7 0.1 0.22 10.8 0.1 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 TPR_17 PF13431.6 EPS29277.1 - 0.23 11.9 1.3 0.55 10.7 0.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EPS29277.1 - 0.35 11.6 2.2 85 4.1 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat RSN1_7TM PF02714.15 EPS29278.1 - 2.1e-80 269.9 23.0 4.7e-80 268.8 22.7 1.7 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate PHM7_cyt PF14703.6 EPS29278.1 - 1.3e-41 142.8 0.0 1.9e-41 142.2 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 EPS29278.1 - 6.3e-39 133.2 1.0 2.2e-38 131.5 0.5 2.3 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport p450 PF00067.22 EPS29279.1 - 4.6e-70 236.7 0.0 5.2e-70 236.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2205 PF10224.9 EPS29279.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Short coiled-coil protein Mito_carr PF00153.27 EPS29280.1 - 3.5e-66 219.2 1.0 4e-24 84.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Pept_tRNA_hydro PF01195.19 EPS29280.1 - 0.065 13.2 0.0 11 5.9 0.0 2.3 2 0 0 2 2 2 0 Peptidyl-tRNA hydrolase Antimicrobial_8 PF08103.11 EPS29280.1 - 0.13 12.4 1.8 17 5.8 0.0 3.1 3 0 0 3 3 3 0 Uperin family APH PF01636.23 EPS29281.1 - 1.3e-41 143.2 0.0 1.9e-41 142.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EPS29281.1 - 8e-05 22.1 0.0 0.00018 20.9 0.0 1.6 1 1 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 EPS29281.1 - 8.8e-05 22.2 0.0 0.00013 21.6 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.14 EPS29281.1 - 0.031 13.5 0.0 0.46 9.6 0.0 2.2 1 1 0 1 1 1 0 Fructosamine kinase Kdo PF06293.14 EPS29281.1 - 0.032 13.6 0.0 0.13 11.6 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EPS29281.1 - 0.084 12.5 0.0 8.1 6.0 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Ank_2 PF12796.7 EPS29282.1 - 2.4e-49 165.8 0.0 3.6e-11 43.5 0.0 7.0 3 2 3 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPS29282.1 - 1e-39 134.4 2.6 2e-08 34.6 0.0 9.9 4 2 8 12 12 12 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 EPS29282.1 - 2.6e-33 113.7 9.1 1.9e-06 28.0 0.1 9.4 5 1 6 11 11 11 8 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPS29282.1 - 1.9e-32 107.6 0.3 0.00015 21.9 0.0 12.0 13 0 0 13 13 13 7 Ankyrin repeat Ank PF00023.30 EPS29282.1 - 1.7e-25 88.3 3.9 0.0058 17.0 0.0 11.7 12 1 0 12 12 12 5 Ankyrin repeat F-box-like PF12937.7 EPS29282.1 - 0.098 12.6 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 F-box-like Porphobil_deam PF01379.20 EPS29283.1 - 3e-72 242.4 0.0 5.2e-72 241.6 0.0 1.4 2 0 0 2 2 2 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 EPS29283.1 - 4.4e-21 75.0 0.2 7.6e-21 74.3 0.2 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain UTRA PF07702.13 EPS29283.1 - 0.051 13.4 0.2 1 9.2 0.2 2.3 2 0 0 2 2 2 0 UTRA domain Ureidogly_lyase PF04115.12 EPS29284.1 - 1.9e-63 213.6 0.0 2.2e-63 213.4 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate lyase GTP_EFTU PF00009.27 EPS29285.1 - 4.1e-50 170.0 0.0 6.5e-50 169.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 EPS29285.1 - 4e-42 142.7 5.0 6.7e-42 142.0 5.0 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 EPS29285.1 - 1.4e-19 69.9 0.0 3.1e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus Ras PF00071.22 EPS29285.1 - 1.1e-05 25.1 0.0 2.9e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.23 EPS29285.1 - 1.8e-05 24.8 0.0 4.9e-05 23.4 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 EPS29285.1 - 7.7e-05 23.0 0.3 0.00037 20.8 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EPS29285.1 - 0.0002 21.4 0.0 0.00049 20.1 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II RF3_C PF16658.5 EPS29285.1 - 0.004 17.0 0.0 0.017 15.0 0.0 2.0 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain MMR_HSR1_Xtn PF16897.5 EPS29285.1 - 0.024 14.6 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain SRPRB PF09439.10 EPS29285.1 - 0.027 13.9 0.0 0.061 12.8 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF1882 PF08966.11 EPS29285.1 - 0.033 14.4 0.9 0.089 13.1 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1882) RsgA_GTPase PF03193.16 EPS29285.1 - 0.1 12.5 0.1 0.56 10.1 0.0 2.2 1 1 1 2 2 2 0 RsgA GTPase Roc PF08477.13 EPS29285.1 - 0.12 12.6 0.0 0.6 10.3 0.0 2.2 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Snurportin1 PF11538.8 EPS29285.1 - 2.6 8.3 6.1 0.58 10.4 2.3 1.9 2 0 0 2 2 2 0 Snurportin1 HORMA PF02301.18 EPS29286.1 - 1.1e-35 123.2 0.0 1.2e-35 123.0 0.0 1.0 1 0 0 1 1 1 1 HORMA domain bacHORMA_2 PF18173.1 EPS29286.1 - 0.056 13.3 0.1 0.12 12.2 0.0 1.6 2 0 0 2 2 2 0 Bacterial HORMA domain 2 DUF4760 PF15956.5 EPS29286.1 - 0.076 13.2 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4760) FlaG PF03646.15 EPS29286.1 - 3.3 7.9 7.4 10 6.3 0.8 2.9 2 1 0 2 2 2 0 FlaG protein DUF218 PF02698.17 EPS29287.1 - 4.3e-05 23.5 0.0 6.1e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain DUF4812 PF16071.5 EPS29288.1 - 0.11 12.3 0.2 0.16 11.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4812) Aldedh PF00171.22 EPS29289.1 - 9e-14 50.8 0.9 1.2e-08 33.9 0.1 2.3 2 1 0 2 2 2 2 Aldehyde dehydrogenase family DUF3810 PF12725.7 EPS29289.1 - 0.1 12.0 0.2 0.17 11.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Phage_GPL PF05926.11 EPS29289.1 - 0.15 12.1 2.2 0.34 10.9 0.6 2.5 2 0 0 2 2 2 0 Phage head completion protein (GPL) Cupin_2 PF07883.11 EPS29290.1 - 1.6e-09 37.3 0.0 3e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.12 EPS29290.1 - 0.012 15.3 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_1 PF00190.22 EPS29290.1 - 0.032 13.8 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 Cupin PepX_C PF08530.10 EPS29291.1 - 7.5e-44 150.3 0.0 1.2e-43 149.7 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 EPS29291.1 - 2.4e-40 138.8 0.7 3.4e-40 138.4 0.7 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 EPS29291.1 - 0.0071 15.6 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 FAD_binding_3 PF01494.19 EPS29292.1 - 3.3e-18 66.1 0.2 7.9e-17 61.5 0.2 2.4 1 1 0 1 1 1 1 FAD binding domain ADC PF06314.11 EPS29292.1 - 6e-12 45.6 0.0 1.2e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) NAD_binding_8 PF13450.6 EPS29292.1 - 2.9e-07 30.6 0.2 1e-06 28.9 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EPS29292.1 - 2.4e-06 27.0 1.9 4.5e-05 22.8 1.9 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EPS29292.1 - 3.1e-06 27.0 1.4 0.0014 18.3 0.8 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EPS29292.1 - 0.00013 21.1 0.3 0.00023 20.4 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 EPS29292.1 - 0.0017 17.3 0.3 0.33 9.8 0.2 2.4 2 0 0 2 2 2 2 Tryptophan halogenase FAD_oxidored PF12831.7 EPS29292.1 - 0.0031 16.9 0.2 0.006 16.0 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EPS29292.1 - 0.0051 15.6 0.1 0.0097 14.6 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 EPS29292.1 - 0.0055 15.8 0.1 0.0087 15.2 0.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 EPS29292.1 - 0.0098 15.2 0.2 3.2 6.9 0.1 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.6 EPS29292.1 - 0.012 15.6 0.2 0.032 14.2 0.2 1.8 1 1 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 EPS29292.1 - 0.021 15.4 1.6 0.033 14.7 0.3 2.1 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EPS29292.1 - 0.12 12.1 0.4 0.23 11.1 0.4 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA HpcH_HpaI PF03328.14 EPS29293.1 - 4.8e-42 143.6 0.0 6.7e-41 139.8 0.0 2.0 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 EPS29293.1 - 7.4e-13 48.4 0.0 2.7e-06 26.8 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold CBP4 PF07960.11 EPS29294.1 - 5.3e-27 94.2 1.5 8.7e-27 93.5 1.5 1.2 1 0 0 1 1 1 1 CBP4 NAM PF02365.15 EPS29294.1 - 0.036 15.0 0.8 0.05 14.5 0.8 1.2 1 0 0 1 1 1 0 No apical meristem (NAM) protein Herpes_UL56 PF04534.12 EPS29294.1 - 0.26 10.7 3.0 0.43 10.0 3.0 1.4 1 0 0 1 1 1 0 Herpesvirus UL56 protein FUSC PF04632.12 EPS29294.1 - 1.2 7.5 3.5 1.4 7.4 3.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family NAD_kinase PF01513.21 EPS29296.1 - 1.1e-45 156.1 0.0 2e-45 155.3 0.0 1.3 1 1 0 1 1 1 1 ATP-NAD kinase MaoC_dehydrat_N PF13452.6 EPS29297.1 - 0.019 15.1 0.0 2 8.6 0.0 2.4 2 1 0 2 2 2 0 N-terminal half of MaoC dehydratase Pyridoxal_deC PF00282.19 EPS29298.1 - 6.5e-103 344.3 0.0 7.7e-103 344.1 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 EPS29298.1 - 3.1e-05 23.4 0.1 4e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aa_trans PF01490.18 EPS29300.1 - 7.2e-47 160.0 31.1 8.3e-47 159.8 31.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EPS29300.1 - 0.0011 18.1 14.4 0.0011 18.1 14.4 3.0 2 1 0 3 3 3 1 Tryptophan/tyrosine permease family S1FA PF04689.13 EPS29300.1 - 7.4 6.8 6.7 5.8 7.1 0.0 3.0 3 0 0 3 3 3 0 DNA binding protein S1FA ATP11 PF06644.11 EPS29301.1 - 2.8e-99 332.3 0.0 3.2e-99 332.1 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein Glyco_hydro_3_C PF01915.22 EPS29302.1 - 5.7e-62 209.3 0.0 1e-61 208.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EPS29302.1 - 1.2e-50 172.7 0.0 2e-50 172.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EPS29302.1 - 5.5e-22 77.7 1.7 2.6e-21 75.5 1.4 2.2 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.12 EPS29302.1 - 6.1e-18 65.0 0.1 1.3e-17 64.0 0.1 1.5 1 0 0 1 1 1 1 PA14 domain GLEYA PF10528.9 EPS29302.1 - 0.0041 17.5 0.3 0.081 13.4 0.1 2.9 3 0 0 3 3 3 1 GLEYA domain DUF11 PF01345.18 EPS29302.1 - 0.057 13.7 0.2 0.24 11.7 0.2 2.1 1 0 0 1 1 1 0 Domain of unknown function DUF11 CARDB PF07705.11 EPS29302.1 - 0.13 12.5 0.1 0.44 10.8 0.0 1.9 2 0 0 2 2 2 0 CARDB ketoacyl-synt PF00109.26 EPS29303.1 - 3e-74 249.8 0.0 5.3e-74 249.0 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain AMP-binding PF00501.28 EPS29303.1 - 4.3e-74 249.6 0.0 7.2e-74 248.9 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EPS29303.1 - 1.9e-64 218.1 0.0 3e-64 217.4 0.0 1.3 1 0 0 1 1 1 1 Condensation domain PS-DH PF14765.6 EPS29303.1 - 1.1e-52 179.1 0.0 1.8e-52 178.4 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.10 EPS29303.1 - 4e-52 176.7 0.4 1.6e-50 171.5 0.1 2.7 3 0 0 3 3 2 1 KR domain Acyl_transf_1 PF00698.21 EPS29303.1 - 3.6e-41 141.7 0.4 6.4e-41 140.9 0.4 1.3 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.12 EPS29303.1 - 4.2e-36 124.4 0.0 2.2e-35 122.1 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.22 EPS29303.1 - 6.7e-30 103.5 0.0 1.8e-29 102.1 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 EPS29303.1 - 2.3e-17 63.1 0.9 2.7e-10 40.5 0.1 3.4 3 0 0 3 3 3 2 Phosphopantetheine attachment site adh_short PF00106.25 EPS29303.1 - 3.1e-17 62.7 0.0 2.1e-14 53.5 0.0 2.9 2 0 0 2 2 2 2 short chain dehydrogenase KAsynt_C_assoc PF16197.5 EPS29303.1 - 3.3e-15 56.5 0.0 6.3e-14 52.4 0.0 2.7 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 EPS29303.1 - 3.6e-13 50.1 0.1 1.4e-12 48.2 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Epimerase PF01370.21 EPS29303.1 - 1e-12 48.0 0.0 3.8e-12 46.2 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.6 EPS29303.1 - 1.3e-12 47.9 0.0 2.9e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPS29303.1 - 1.6e-12 47.5 0.0 4.8e-12 45.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPS29303.1 - 1.9e-11 44.5 0.0 7.6e-11 42.6 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS29303.1 - 3.7e-10 40.3 0.0 1.4e-09 38.5 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain 3Beta_HSD PF01073.19 EPS29303.1 - 1e-06 28.0 0.0 4.4e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ubie_methyltran PF01209.18 EPS29303.1 - 2.3e-05 23.8 0.0 4.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family AMP-binding_C PF13193.6 EPS29303.1 - 0.00013 22.9 0.0 0.00036 21.4 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltransf_16 PF10294.9 EPS29303.1 - 0.00059 19.6 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase GDP_Man_Dehyd PF16363.5 EPS29303.1 - 0.00082 18.9 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Thiolase_N PF00108.23 EPS29303.1 - 0.0014 18.0 0.0 0.0033 16.8 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain NAD_binding_10 PF13460.6 EPS29303.1 - 0.0026 17.7 0.0 0.0064 16.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H-binding MFS_1 PF07690.16 EPS29304.1 - 9.1e-36 123.5 24.6 9.1e-36 123.5 24.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily PgaD PF13994.6 EPS29304.1 - 0.15 12.1 1.6 1.9 8.5 0.0 2.7 3 0 0 3 3 3 0 PgaD-like protein DUF3140 PF11338.8 EPS29305.1 - 5.1e-36 123.0 0.3 5.9e-36 122.8 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3140) TauD PF02668.16 EPS29306.1 - 7.8e-07 29.2 0.0 7.7e-05 22.6 0.0 2.1 2 0 0 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family ADH_zinc_N PF00107.26 EPS29307.1 - 2e-09 37.5 0.4 3.3e-09 36.8 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPS29307.1 - 0.0013 18.5 0.0 0.0076 16.1 0.0 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EPS29307.1 - 0.12 13.5 0.0 0.22 12.6 0.0 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Cript PF10235.9 EPS29307.1 - 0.2 12.2 0.3 0.36 11.4 0.3 1.3 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT Zn_clus PF00172.18 EPS29308.1 - 0.00089 19.3 10.0 0.0017 18.4 10.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.24 EPS29309.1 - 8.4e-32 110.5 0.7 1.4e-31 109.7 0.7 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EPS29309.1 - 2.8e-21 75.5 0.1 4.4e-21 74.9 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EPS29309.1 - 1.6e-10 41.4 0.0 3e-10 40.5 0.0 1.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 EPS29309.1 - 2e-05 24.4 0.0 3.9e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Acyl-CoA_dh_N PF02771.16 EPS29309.1 - 2.2e-05 25.0 0.0 8e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain AA_permease PF00324.21 EPS29310.1 - 3.8e-126 421.5 48.6 5.1e-126 421.1 48.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EPS29310.1 - 1.8e-29 102.9 52.8 2.4e-29 102.4 52.8 1.1 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.16 EPS29312.1 - 2.6e-43 148.3 23.6 2.6e-43 148.3 23.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Zn_clus PF00172.18 EPS29313.1 - 4.2e-07 30.0 11.2 1e-06 28.7 11.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.13 EPS29314.1 - 5.5e-51 173.1 8.2 5.5e-51 173.1 8.2 1.9 1 1 1 2 2 2 1 RTA1 like protein OAD_gamma PF04277.13 EPS29314.1 - 0.26 11.9 5.5 60 4.3 0.0 4.4 4 0 0 4 4 4 0 Oxaloacetate decarboxylase, gamma chain DUF2992 PF11208.8 EPS29314.1 - 7.4 6.8 15.1 14 5.9 15.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Coilin_N PF15862.5 EPS29314.1 - 7.6 6.3 10.1 12 5.7 10.1 1.2 1 0 0 1 1 1 0 Coilin N-terminus FMO-like PF00743.19 EPS29315.1 - 3e-08 32.6 0.0 1.6e-05 23.5 0.0 3.5 4 0 0 4 4 4 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EPS29315.1 - 3.2e-06 26.5 0.0 0.0017 17.5 0.0 3.3 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.6 EPS29315.1 - 0.00017 20.9 0.0 0.0084 15.4 0.0 3.1 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPS29315.1 - 0.00049 20.3 0.4 1.3 9.3 0.0 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EPS29315.1 - 0.0026 17.1 0.0 1.8 7.7 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EPS29315.1 - 0.19 10.4 0.1 2.4 6.8 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein Rieske PF00355.26 EPS29316.1 - 7.5e-16 57.9 0.0 1.4e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Ring_hydroxyl_A PF00848.19 EPS29316.1 - 3.9e-05 23.7 0.0 0.00019 21.5 0.0 2.0 1 1 1 2 2 2 1 Ring hydroxylating alpha subunit (catalytic domain) BNIP3 PF06553.12 EPS29316.1 - 0.1 12.3 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 BNIP3 Zn_clus PF00172.18 EPS29317.1 - 3.6e-10 39.8 10.1 1e-09 38.4 10.1 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPS29317.1 - 2.9e-09 36.4 2.3 5.1e-09 35.5 2.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain AA_permease_2 PF13520.6 EPS29318.1 - 2.2e-46 158.6 55.5 2.7e-46 158.3 55.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPS29318.1 - 1.3e-20 73.5 46.3 1.8e-20 73.0 46.3 1.1 1 0 0 1 1 1 1 Amino acid permease PalH PF08733.10 EPS29318.1 - 3.7 6.5 9.4 7.9 5.4 9.4 1.5 1 0 0 1 1 1 0 PalH/RIM21 Arylsulfotran_2 PF14269.6 EPS29320.1 - 6.8e-58 196.4 1.2 9.8e-58 195.9 1.2 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 EPS29320.1 - 5.5e-15 55.2 1.3 2.6e-14 53.0 1.3 2.0 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) PQQ PF01011.21 EPS29320.1 - 0.089 12.8 0.0 24 5.1 0.0 3.4 3 0 0 3 3 3 0 PQQ enzyme repeat GMC_oxred_C PF05199.13 EPS29321.1 - 1.8e-30 106.4 0.0 3.1e-30 105.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EPS29321.1 - 1.9e-28 99.7 0.0 2.3e-18 66.6 0.0 3.2 3 0 0 3 3 3 3 GMC oxidoreductase NAD_binding_8 PF13450.6 EPS29321.1 - 0.00091 19.4 0.0 0.0022 18.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EPS29321.1 - 0.014 14.7 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HHH PF00633.23 EPS29321.1 - 0.052 13.4 0.2 5 7.2 0.0 3.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif Lycopene_cycl PF05834.12 EPS29321.1 - 0.072 12.1 0.3 0.11 11.5 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.24 EPS29321.1 - 0.092 11.8 0.3 0.15 11.1 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_binding_3 PF01494.19 EPS29321.1 - 0.14 11.4 0.2 0.22 10.7 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 EPS29321.1 - 0.2 10.9 0.0 15 4.7 0.0 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase CFEM PF05730.11 EPS29322.1 - 7.1e-14 51.7 14.3 1.4e-13 50.7 14.3 1.5 1 0 0 1 1 1 1 CFEM domain Peroxidase_2 PF01328.17 EPS29324.1 - 1.1e-41 143.4 0.0 1.5e-41 143.0 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 p450 PF00067.22 EPS29325.1 - 2.4e-71 240.9 0.0 2.9e-71 240.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 EPS29327.1 - 5.9e-27 94.5 62.4 1.1e-23 83.7 43.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRAPP PF04051.16 EPS29327.1 - 0.16 11.7 0.0 5.4 6.7 0.0 2.3 2 0 0 2 2 2 0 Transport protein particle (TRAPP) component adh_short PF00106.25 EPS29328.1 - 5.9e-22 78.1 0.1 9.4e-22 77.4 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS29328.1 - 5.5e-15 55.6 0.2 8.9e-15 54.9 0.2 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPS29328.1 - 2.1e-08 34.3 2.3 3.3e-08 33.6 0.7 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EPS29328.1 - 8.8e-05 22.1 0.1 0.00023 20.7 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EPS29328.1 - 0.011 15.7 0.5 0.016 15.1 0.5 1.4 1 0 0 1 1 1 0 NAD(P)H-binding NmrA PF05368.13 EPS29328.1 - 0.11 12.1 0.2 0.17 11.4 0.2 1.4 1 0 0 1 1 1 0 NmrA-like family RTA1 PF04479.13 EPS29330.1 - 5e-61 205.9 10.9 5e-61 205.9 10.9 1.3 2 0 0 2 2 2 1 RTA1 like protein bZIP_1 PF00170.21 EPS29331.1 - 0.00021 21.3 1.5 0.00045 20.3 1.5 1.5 1 0 0 1 1 1 1 bZIP transcription factor Pox_A_type_inc PF04508.12 EPS29331.1 - 0.041 13.7 0.5 0.041 13.7 0.5 2.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat bZIP_2 PF07716.15 EPS29331.1 - 0.053 13.6 0.8 0.12 12.5 0.8 1.6 1 0 0 1 1 1 0 Basic region leucine zipper adh_short PF00106.25 EPS29332.1 - 8.7e-43 146.1 1.1 1.2e-42 145.6 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS29332.1 - 2e-31 109.4 0.0 2.7e-31 108.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EPS29332.1 - 1.8e-06 28.0 0.2 3.5e-06 27.0 0.1 1.5 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EPS29332.1 - 3e-06 27.0 0.4 5e-06 26.2 0.4 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 EPS29332.1 - 3.5e-06 27.1 0.3 5.2e-06 26.5 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPS29332.1 - 0.00034 20.2 0.2 0.00052 19.5 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EPS29332.1 - 0.011 15.1 0.5 0.017 14.6 0.1 1.4 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 EPS29332.1 - 0.013 15.7 0.1 0.024 14.9 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain ADH_zinc_N PF00107.26 EPS29332.1 - 0.014 15.4 1.1 0.069 13.1 1.1 2.0 1 1 0 1 1 1 0 Zinc-binding dehydrogenase RmlD_sub_bind PF04321.17 EPS29332.1 - 0.058 12.5 0.0 0.079 12.0 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain ApbA PF02558.16 EPS29332.1 - 0.09 12.4 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DNA_pol_lambd_f PF10391.9 EPS29332.1 - 0.14 12.0 0.0 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda Antifungal_prot PF11402.8 EPS29334.1 - 2.9e-22 78.7 16.1 3.9e-22 78.2 16.1 1.2 1 0 0 1 1 1 1 Antifungal protein Spheroidin PF05541.12 EPS29334.1 - 0.042 11.7 3.1 0.044 11.6 3.1 1.0 1 0 0 1 1 1 0 Entomopoxvirus spheroidin protein DUF3970 PF13113.6 EPS29334.1 - 0.13 12.5 0.8 0.21 11.8 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3970) DUF3632 PF12311.8 EPS29335.1 - 1.7e-09 38.3 0.0 2e-08 34.9 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF3632) DUF3818 PF12825.7 EPS29336.1 - 0.091 11.8 0.5 0.14 11.1 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) Thiolase_C PF02803.18 EPS29337.1 - 0.19 11.4 5.3 0.031 13.9 1.6 1.7 2 0 0 2 2 2 0 Thiolase, C-terminal domain Cu_amine_oxid PF01179.20 EPS29340.1 - 1.5e-162 541.2 0.4 1.8e-162 540.9 0.4 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 EPS29340.1 - 5.1e-06 26.8 0.0 1.4e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 EPS29340.1 - 0.0031 17.7 0.2 0.0062 16.7 0.2 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DUF5026 PF16429.5 EPS29340.1 - 0.019 15.0 0.1 0.072 13.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5026) B_lectin PF01453.24 EPS29342.1 - 0.1 13.1 1.1 0.24 12.0 1.1 1.5 1 0 0 1 1 1 0 D-mannose binding lectin Aldolase_II PF00596.21 EPS29343.1 - 3.1e-49 167.4 0.1 4.1e-49 167.0 0.1 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Retrotrans_gag PF03732.17 EPS29344.1 - 0.0074 16.5 3.2 0.38 11.0 0.1 3.3 4 0 0 4 4 4 2 Retrotransposon gag protein Lipase_2 PF01674.18 EPS29345.1 - 9.1e-09 35.1 0.0 3.5e-08 33.2 0.0 1.9 1 1 0 1 1 1 1 Lipase (class 2) Abhydrolase_1 PF00561.20 EPS29345.1 - 1.9e-06 27.7 0.3 0.00019 21.1 0.3 3.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPS29345.1 - 0.00024 21.8 0.1 0.00031 21.4 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPS29345.1 - 0.0026 17.1 0.0 0.0039 16.5 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Palm_thioest PF02089.15 EPS29345.1 - 0.0047 16.8 0.0 0.02 14.7 0.0 1.8 2 0 0 2 2 2 1 Palmitoyl protein thioesterase DUF676 PF05057.14 EPS29345.1 - 0.006 16.1 0.0 0.01 15.4 0.0 1.3 1 1 0 1 1 1 1 Putative serine esterase (DUF676) DUF900 PF05990.12 EPS29345.1 - 0.098 12.2 0.0 0.42 10.1 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.13 EPS29345.1 - 0.1 12.3 0.1 0.22 11.2 0.1 1.5 1 1 0 1 1 1 0 PGAP1-like protein Abhydrolase_2 PF02230.16 EPS29345.1 - 0.11 12.2 0.1 6.3 6.5 0.0 2.3 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase DUF915 PF06028.11 EPS29345.1 - 0.14 11.5 0.0 0.97 8.7 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Zn_clus PF00172.18 EPS29346.1 - 1.6e-05 24.9 13.5 3.6e-05 23.8 13.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EPS29346.1 - 0.00045 19.2 0.0 0.0025 16.7 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.16 EPS29348.1 - 1.1e-33 116.6 30.4 1.7e-33 116.0 30.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily IATP PF04568.12 EPS29350.1 - 1.1e-20 73.9 1.1 1.2e-20 73.7 1.1 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP TMF_DNA_bd PF12329.8 EPS29350.1 - 0.019 15.0 6.2 0.028 14.4 6.2 1.4 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding RFamide_26RFa PF11109.8 EPS29350.1 - 0.046 14.2 1.7 0.053 14.0 1.7 1.1 1 0 0 1 1 1 0 Orexigenic neuropeptide Qrfp/P518 PPL5 PF18168.1 EPS29350.1 - 0.11 11.8 1.9 0.13 11.6 1.9 1.0 1 0 0 1 1 1 0 Prim-pol family 5 DUF3138 PF11336.8 EPS29350.1 - 0.19 10.3 0.4 0.29 9.7 0.1 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3138) GARP PF16731.5 EPS29350.1 - 0.19 11.4 4.1 3.3 7.4 3.8 2.0 1 1 1 2 2 2 0 Glutamic acid/alanine-rich protein of Trypanosoma DUF4446 PF14584.6 EPS29350.1 - 0.24 11.4 2.3 0.31 11.0 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) ABC2_membrane PF01061.24 EPS29351.1 - 1.1e-84 283.1 43.8 6.5e-48 162.9 17.0 2.3 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 EPS29351.1 - 6.3e-42 143.4 0.0 2.7e-19 70.0 0.0 3.4 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 EPS29351.1 - 6.6e-28 96.5 8.7 1.8e-26 91.9 0.0 3.5 3 0 0 3 3 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 EPS29351.1 - 9.4e-11 41.4 29.5 7.7e-08 31.8 9.3 2.5 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.6 EPS29351.1 - 0.00015 22.2 0.6 0.053 13.9 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EPS29351.1 - 0.00016 21.4 1.0 0.1 12.4 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_trans_N PF14510.6 EPS29351.1 - 0.00023 21.7 0.1 0.00023 21.7 0.1 1.9 2 0 0 2 2 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 EPS29351.1 - 0.00024 21.0 0.3 0.019 14.9 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_25 PF13481.6 EPS29351.1 - 0.001 18.7 0.2 0.011 15.3 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EPS29351.1 - 0.0017 18.7 0.8 0.86 9.9 0.2 3.3 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.6 EPS29351.1 - 0.0043 17.6 0.1 5.3 7.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EPS29351.1 - 0.006 16.8 0.7 2.3 8.4 0.2 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EPS29351.1 - 0.012 15.8 2.1 1.1 9.4 0.8 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EPS29351.1 - 0.037 14.1 0.3 9.6 6.3 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase DDHD PF02862.17 EPS29351.1 - 0.1 12.7 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 DDHD domain AAA_30 PF13604.6 EPS29351.1 - 0.11 12.2 0.6 6.3 6.5 0.4 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EPS29351.1 - 0.15 11.9 0.6 2.2 8.1 0.1 2.3 2 0 0 2 2 2 0 NACHT domain AAA_21 PF13304.6 EPS29351.1 - 0.16 11.7 0.0 5.3 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 EPS29351.1 - 0.96 9.0 3.5 2 8.0 0.4 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain XPA_N PF01286.18 EPS29352.1 - 0.52 10.4 4.4 11 6.2 0.2 2.4 2 0 0 2 2 2 0 XPA protein N-terminal TspO_MBR PF03073.15 EPS29353.1 - 1.3e-45 154.8 8.9 1.5e-45 154.5 8.9 1.1 1 0 0 1 1 1 1 TspO/MBR family ThrE PF06738.12 EPS29354.1 - 1.4e-78 263.6 16.9 7.3e-71 238.3 5.1 2.3 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 EPS29354.1 - 5.1e-13 49.3 9.8 5.1e-13 49.3 9.8 2.6 2 0 0 2 2 2 1 Threonine/Serine exporter, ThrE Asparaginase_II PF06089.12 EPS29355.1 - 4.4e-119 397.3 0.1 5e-119 397.1 0.1 1.0 1 0 0 1 1 1 1 L-asparaginase II HNH_2 PF13391.6 EPS29356.1 - 0.0048 17.0 0.0 0.0093 16.1 0.0 1.6 1 0 0 1 1 1 1 HNH endonuclease Ank_2 PF12796.7 EPS29357.1 - 1.7e-14 54.1 1.3 1.5e-07 31.9 0.3 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPS29357.1 - 6.1e-11 42.6 0.4 0.0035 17.9 0.0 4.0 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPS29357.1 - 6.5e-08 32.3 0.7 9.7 7.1 0.0 5.9 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 EPS29357.1 - 2.3e-07 30.9 0.6 0.00029 21.1 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EPS29357.1 - 0.043 14.3 3.5 22 5.7 0.1 4.2 4 0 0 4 4 4 0 Ankyrin repeat DDE_1 PF03184.19 EPS29358.1 - 5.7e-11 42.4 0.0 1.4e-10 41.1 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease Acetyltransf_7 PF13508.7 EPS29360.1 - 9.9e-07 29.1 0.0 1.5e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPS29360.1 - 9.3e-06 25.9 0.0 1.4e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EPS29360.1 - 2.1e-05 24.5 0.0 3.1e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPS29360.1 - 0.00017 21.5 0.0 0.00032 20.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EPS29360.1 - 0.00028 21.0 0.0 0.00045 20.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 EPS29360.1 - 0.0014 18.3 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 GNAT acetyltransferase DUF4416 PF14385.6 EPS29360.1 - 0.051 13.5 0.0 0.075 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4416) Acetyltransf_CG PF14542.6 EPS29360.1 - 0.064 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Cellulase PF00150.18 EPS29361.1 - 1.2e-15 57.7 7.9 1.8e-15 57.2 7.9 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) E3_UFM1_ligase PF09743.9 EPS29361.1 - 0.23 11.0 0.0 0.36 10.4 0.0 1.2 1 0 0 1 1 1 0 E3 UFM1-protein ligase 1 Zn_clus PF00172.18 EPS29362.1 - 2.5e-09 37.1 9.9 2.5e-09 37.1 9.9 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPS29362.1 - 4.8e-08 32.4 0.9 9e-08 31.5 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Mak10 PF04112.13 EPS29363.1 - 2.2e-65 219.3 0.0 3.6e-65 218.6 0.0 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase ATP-synt_Eps PF04627.13 EPS29364.1 - 1.6e-24 85.6 3.6 2.4e-24 85.0 3.6 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Cwf_Cwc_15 PF04889.12 EPS29365.1 - 0.0021 17.9 11.7 0.003 17.3 11.7 1.3 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein YL1 PF05764.13 EPS29365.1 - 0.031 14.4 11.1 0.046 13.8 11.1 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Myc_N PF01056.18 EPS29365.1 - 0.044 13.7 7.1 0.12 12.2 7.1 1.7 1 1 0 1 1 1 0 Myc amino-terminal region RNA_pol_3_Rpc31 PF11705.8 EPS29365.1 - 0.13 12.5 14.0 0.27 11.5 14.0 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CDC45 PF02724.14 EPS29365.1 - 0.42 8.9 14.0 0.56 8.4 14.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Astro_capsid_p PF12226.8 EPS29365.1 - 0.58 9.3 9.8 0.99 8.5 9.8 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DUF2457 PF10446.9 EPS29365.1 - 0.68 9.0 15.5 1.2 8.2 15.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RPN2_C PF18004.1 EPS29365.1 - 1 9.2 5.7 0.4 10.6 2.7 1.7 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain Nop14 PF04147.12 EPS29365.1 - 1.1 7.3 13.6 1.4 7.1 13.6 1.1 1 0 0 1 1 1 0 Nop14-like family Cpn60_TCP1 PF00118.24 EPS29366.1 - 1.2e-86 291.3 8.0 1.8e-86 290.7 8.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phosphoesterase PF04185.14 EPS29367.1 - 6.3e-33 114.4 3.6 1e-32 113.7 3.6 1.3 1 0 0 1 1 1 1 Phosphoesterase family HIF-1a_CTAD PF08778.10 EPS29367.1 - 0.073 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 HIF-1 alpha C terminal transactivation domain HATPase_c PF02518.26 EPS29368.1 - 1.6e-30 105.9 0.1 4.5e-30 104.4 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAMP PF00672.25 EPS29368.1 - 3.3e-30 104.2 12.3 1.2e-09 38.4 0.2 6.7 5 1 0 5 5 5 4 HAMP domain Response_reg PF00072.24 EPS29368.1 - 1.1e-26 93.2 0.7 3.1e-26 91.7 0.7 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EPS29368.1 - 1.8e-16 59.9 1.3 6.2e-16 58.2 0.2 2.7 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain DUF1843 PF08898.10 EPS29368.1 - 0.00036 21.0 0.3 22 5.6 0.0 5.2 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) DUF3829 PF12889.7 EPS29368.1 - 0.023 14.2 1.3 2.5 7.5 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3829) Syntaxin_2 PF14523.6 EPS29368.1 - 0.034 14.5 10.7 3.2 8.2 0.1 5.1 6 0 0 6 6 6 0 Syntaxin-like protein IcmF_C PF06744.12 EPS29368.1 - 0.067 12.8 0.9 0.96 9.0 0.0 2.8 3 0 0 3 3 3 0 Type VI secretion protein IcmF C-terminal DUF948 PF06103.11 EPS29368.1 - 0.072 13.4 32.8 0.21 11.9 1.3 7.2 6 3 0 7 7 5 0 Bacterial protein of unknown function (DUF948) DUF2200 PF09966.9 EPS29368.1 - 0.088 13.0 0.5 60 3.8 0.0 3.9 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2200) BORCS6 PF10157.9 EPS29368.1 - 0.32 11.2 5.2 13 5.9 0.0 4.2 4 1 0 4 4 4 0 BLOC-1-related complex sub-unit 6 Flagellin_C PF00700.21 EPS29368.1 - 0.35 11.2 6.1 12 6.4 0.4 4.0 3 0 0 3 3 3 0 Bacterial flagellin C-terminal helical region Filament PF00038.21 EPS29368.1 - 0.73 9.4 6.3 1.8 8.1 3.1 3.0 2 1 0 2 2 2 0 Intermediate filament protein BLOC1_2 PF10046.9 EPS29368.1 - 1.2 9.5 6.4 4.2 7.8 0.1 4.4 5 0 0 5 5 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DASH_Dad2 PF08654.10 EPS29368.1 - 3 8.3 12.5 16 6.0 0.1 5.0 4 1 0 4 4 4 0 DASH complex subunit Dad2 CRIC_ras_sig PF10534.9 EPS29368.1 - 3.7 7.8 6.8 4.3 7.6 0.2 4.0 4 0 0 4 4 4 0 Connector enhancer of kinase suppressor of ras Jnk-SapK_ap_N PF09744.9 EPS29368.1 - 4 7.7 9.0 3.7 7.8 1.3 3.4 4 0 0 4 4 4 0 JNK_SAPK-associated protein-1 HrpB7 PF09486.10 EPS29368.1 - 4.3 7.7 7.4 10 6.5 0.2 4.3 5 0 0 5 5 4 0 Bacterial type III secretion protein (HrpB7) CENP-F_leu_zip PF10473.9 EPS29368.1 - 6.6 6.8 14.7 99 2.9 2.2 6.0 5 3 2 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CorA PF01544.18 EPS29369.1 - 2.7e-09 36.8 0.5 2.7e-09 36.8 0.5 2.0 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF676 PF05057.14 EPS29369.1 - 8.6e-06 25.4 0.0 1.6e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 EPS29369.1 - 0.042 13.1 0.0 0.094 12.0 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Phage_holin_3_6 PF07332.11 EPS29369.1 - 0.14 12.2 0.1 0.31 11.1 0.1 1.5 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III INCA1 PF15142.6 EPS29369.1 - 0.96 9.4 4.3 7.7 6.5 0.1 3.1 3 0 0 3 3 3 0 INCA1 Mito_carr PF00153.27 EPS29370.1 - 3.9e-63 209.4 1.0 1e-20 73.4 0.0 4.1 4 0 0 4 4 4 4 Mitochondrial carrier protein Serine_protease PF18405.1 EPS29370.1 - 0.0076 15.4 0.1 0.17 11.0 0.0 2.2 2 0 0 2 2 2 2 Gammaproteobacterial serine protease F-box-like PF12937.7 EPS29371.1 - 2.3e-08 33.8 0.2 5.2e-08 32.7 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EPS29371.1 - 0.00014 21.6 0.0 0.00031 20.6 0.0 1.5 1 0 0 1 1 1 1 F-box domain TPR_2 PF07719.17 EPS29371.1 - 0.0022 17.9 0.3 1.1 9.6 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EPS29371.1 - 0.021 14.6 0.1 1.1 9.2 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 EPS29371.1 - 0.027 14.6 0.2 0.047 13.7 0.2 1.3 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Mucin PF01456.17 EPS29371.1 - 2.5 8.1 5.6 4.7 7.2 5.6 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Aa_trans PF01490.18 EPS29372.1 - 7e-40 137.0 34.4 8.1e-40 136.8 34.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Caveolin PF01146.17 EPS29372.1 - 0.67 9.9 0.0 0.67 9.9 0.0 3.2 2 1 1 3 3 3 0 Caveolin Pox_A14 PF05767.12 EPS29372.1 - 3.5 7.8 14.7 1.4 9.1 4.5 3.9 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 PAS_9 PF13426.7 EPS29373.1 - 1.2e-17 64.1 0.0 1.3e-14 54.3 0.0 2.4 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 EPS29373.1 - 1.2e-06 28.5 0.0 0.0039 17.2 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 EPS29373.1 - 0.0005 20.3 0.3 0.41 11.0 0.0 2.9 3 0 0 3 3 3 2 PAS fold PAS_4 PF08448.10 EPS29373.1 - 0.0044 17.2 0.0 1.9 8.8 0.0 2.7 3 0 0 3 3 3 2 PAS fold HA2 PF04408.23 EPS29374.1 - 2.6e-22 79.1 0.1 7.9e-22 77.6 0.1 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EPS29374.1 - 6e-14 52.2 0.0 1.4e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EPS29374.1 - 2.8e-12 46.9 0.0 6.6e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EPS29374.1 - 0.0012 19.2 0.0 0.004 17.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EPS29374.1 - 0.0046 16.7 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_24 PF13479.6 EPS29374.1 - 0.034 13.9 0.0 0.075 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EPS29374.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase ATPase PF06745.13 EPS29374.1 - 0.077 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.6 EPS29374.1 - 0.084 13.2 0.0 0.29 11.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 EPS29374.1 - 0.095 11.7 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 EPS29374.1 - 0.13 12.8 0.0 0.31 11.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AXIN1_TNKS_BD PF16646.5 EPS29374.1 - 0.65 11.0 7.5 17 6.4 0.1 3.3 2 1 0 2 2 2 0 Axin-1 tankyrase binding domain CFEM PF05730.11 EPS29377.1 - 1.6e-08 34.5 10.2 2.1e-08 34.2 10.2 1.2 1 0 0 1 1 1 1 CFEM domain Alpha_TIF PF02232.15 EPS29377.1 - 0.16 11.1 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 Alpha trans-inducing protein (Alpha-TIF) Ribosomal_L16 PF00252.18 EPS29378.1 - 1.9e-45 154.1 0.2 2.5e-45 153.7 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_L7Ae PF01248.26 EPS29379.1 - 3.8e-25 87.5 0.0 4.3e-25 87.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family FapA PF03961.13 EPS29380.1 - 3.1 6.3 8.9 7.4 5.1 8.9 1.6 1 0 0 1 1 1 0 Flagellar Assembly Protein A Bacillus_HBL PF05791.11 EPS29380.1 - 4 7.2 8.6 0.76 9.6 3.8 2.0 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DotU PF09850.9 EPS29380.1 - 9.7 5.8 9.1 48 3.6 8.2 2.5 1 1 1 2 2 2 0 Type VI secretion system protein DotU Clat_adaptor_s PF01217.20 EPS29381.1 - 3.8e-12 46.3 0.0 1.3e-10 41.4 0.1 2.0 2 0 0 2 2 2 2 Clathrin adaptor complex small chain NFACT-C PF11923.8 EPS29382.1 - 4.9e-40 135.7 0.1 4.9e-40 135.7 0.1 4.1 4 0 0 4 4 4 1 NFACT protein C-terminal domain FbpA PF05833.11 EPS29382.1 - 5.3e-33 114.5 19.8 5.3e-33 114.5 19.8 2.6 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 EPS29382.1 - 7.6e-27 94.1 0.0 2.6e-26 92.4 0.0 1.9 2 0 0 2 2 2 1 NFACT protein RNA binding domain Cas_TM1802 PF09484.10 EPS29382.1 - 0.011 14.5 0.0 0.094 11.4 0.0 2.0 1 1 0 1 1 1 0 CRISPR-associated protein TM1802 (cas_TM1802) DCA16 PF15349.6 EPS29382.1 - 3.4 7.2 5.2 14 5.1 0.0 2.6 2 0 0 2 2 2 0 DDB1- and CUL4-associated factor 16 Sua5_yciO_yrdC PF01300.18 EPS29383.1 - 4.6e-56 189.2 0.0 7.2e-56 188.5 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 EPS29383.1 - 5.1e-32 111.2 0.0 1e-31 110.2 0.0 1.5 2 0 0 2 2 2 1 Putative GTP-binding controlling metal-binding A_deaminase PF00962.22 EPS29384.1 - 2.3e-78 263.8 0.0 2.6e-78 263.7 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_1 PF01979.20 EPS29384.1 - 0.0017 17.7 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family 2Fe-2S_thioredx PF01257.19 EPS29386.1 - 6.7e-60 201.1 0.1 8.6e-60 200.8 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin SNF2_N PF00176.23 EPS29387.1 - 1.8e-18 66.4 0.0 6.9e-13 48.0 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.17 EPS29387.1 - 1.1e-13 51.3 0.0 2.5e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase zf-RING_UBOX PF13445.6 EPS29387.1 - 0.036 14.1 8.1 0.069 13.2 0.5 2.7 2 0 0 2 2 2 0 RING-type zinc-finger Helicase_C PF00271.31 EPS29387.1 - 0.056 13.8 0.0 0.19 12.0 0.0 1.9 1 1 0 1 1 1 0 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 EPS29387.1 - 0.39 10.7 15.6 0.36 10.8 4.7 2.8 2 0 0 2 2 2 0 zinc-RING finger domain CSTF2_hinge PF14327.6 EPS29388.1 - 1.7e-31 108.5 2.1 1.7e-31 108.5 2.1 2.3 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.22 EPS29388.1 - 1.5e-19 69.6 0.0 2.2e-19 69.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.6 EPS29388.1 - 1e-17 63.4 16.3 2.6e-17 62.1 11.6 2.9 2 0 0 2 2 2 1 Transcription termination and cleavage factor C-terminal RRM_7 PF16367.5 EPS29388.1 - 0.011 15.9 0.1 0.87 9.8 0.0 2.4 1 1 1 2 2 2 0 RNA recognition motif RRM_occluded PF16842.5 EPS29388.1 - 0.013 15.3 0.0 0.039 13.8 0.0 1.7 1 1 0 1 1 1 0 Occluded RNA-recognition motif Spo7_2_N PF15407.6 EPS29388.1 - 0.016 14.8 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 Sporulation protein family 7 RRM_Rrp7 PF17799.1 EPS29388.1 - 0.017 14.9 0.0 1.7 8.4 0.0 2.2 1 1 1 2 2 2 0 Rrp7 RRM-like N-terminal domain RRM_5 PF13893.6 EPS29388.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Band_7 PF01145.25 EPS29389.1 - 7.4e-24 84.7 4.0 1.1e-23 84.1 4.0 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Ank_2 PF12796.7 EPS29390.1 - 0.0074 16.8 0.1 0.83 10.3 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 EPS29390.1 - 0.0091 16.4 0.0 0.024 15.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat BUD22 PF09073.10 EPS29390.1 - 0.55 9.5 6.5 0.79 9.0 6.5 1.2 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 EPS29390.1 - 0.72 9.2 9.9 0.94 8.8 9.9 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EPS29390.1 - 0.94 7.6 7.7 1.1 7.4 7.7 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EPS29390.1 - 4.5 5.5 7.4 7 4.8 7.4 1.2 1 0 0 1 1 1 0 CDC45-like protein RSN1_7TM PF02714.15 EPS29391.1 - 8.5e-86 287.7 30.6 8.5e-86 287.7 30.6 1.5 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EPS29391.1 - 1.4e-46 158.1 0.2 1.4e-46 158.1 0.2 3.6 2 1 1 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EPS29391.1 - 1.4e-30 106.8 2.4 1.6e-17 64.3 0.7 2.7 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 EPS29391.1 - 8.2e-14 51.5 0.0 2.8e-13 49.8 0.0 1.9 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter MCM PF00493.23 EPS29392.1 - 1.9e-101 337.8 0.0 2.8e-101 337.3 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EPS29392.1 - 1.1e-38 132.0 0.8 2.5e-38 130.8 0.8 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EPS29392.1 - 4.8e-29 100.6 1.8 1.1e-28 99.4 1.8 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EPS29392.1 - 8.1e-18 64.9 0.0 2.7e-17 63.2 0.0 2.0 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 EPS29392.1 - 3.3e-05 23.9 0.0 8.7e-05 22.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EPS29392.1 - 3.9e-05 23.1 0.0 0.0014 18.0 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EPS29392.1 - 0.0034 17.3 0.0 0.011 15.6 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EPS29392.1 - 0.084 12.6 0.1 1.7 8.3 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain VTC PF09359.10 EPS29394.1 - 6.5e-101 337.3 0.1 6.5e-101 337.3 0.1 1.6 2 0 0 2 2 2 1 VTC domain DUF202 PF02656.15 EPS29394.1 - 3.6e-12 46.5 5.4 6.5e-12 45.7 4.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) SPX PF03105.19 EPS29394.1 - 3.8e-09 36.9 21.5 6.9e-05 22.9 0.4 3.6 3 1 1 4 4 4 3 SPX domain TMEM100 PF16311.5 EPS29394.1 - 0.1 12.2 0.1 0.21 11.2 0.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 100 RexA PF15969.5 EPS29394.1 - 0.16 11.5 0.1 0.32 10.5 0.1 1.5 1 0 0 1 1 1 0 Intracellular sensor of Lambda phage, Abi component YabA PF06156.13 EPS29396.1 - 0.0029 18.2 2.4 2.7 8.7 3.8 2.5 1 1 1 2 2 2 2 Initiation control protein YabA DUF4665 PF15679.5 EPS29396.1 - 0.038 14.6 1.2 0.093 13.4 0.2 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4665) Fez1 PF06818.15 EPS29396.1 - 0.065 13.7 5.7 0.093 13.2 5.7 1.2 1 0 0 1 1 1 0 Fez1 DUF641 PF04859.12 EPS29396.1 - 3.3 8.1 5.6 6.3 7.2 1.7 2.3 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) MCC-bdg_PDZ PF10506.9 EPS29396.1 - 3.8 7.6 6.4 7.7 6.6 0.1 2.8 3 1 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome SKA2 PF16740.5 EPS29397.1 - 5.4e-05 22.9 7.8 0.00035 20.3 4.7 2.0 1 1 1 2 2 2 1 Spindle and kinetochore-associated protein 2 FPP PF05911.11 EPS29397.1 - 0.00012 20.5 10.5 0.00013 20.4 10.5 1.0 1 0 0 1 1 1 1 Filament-like plant protein, long coiled-coil Spc7 PF08317.11 EPS29397.1 - 0.00063 18.7 11.7 0.00079 18.4 11.7 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein AIP3 PF03915.13 EPS29397.1 - 0.0058 15.8 5.2 0.0063 15.7 5.2 1.0 1 0 0 1 1 1 1 Actin interacting protein 3 SKA1 PF07160.12 EPS29397.1 - 0.0093 15.8 8.3 0.061 13.2 3.8 2.0 1 1 1 2 2 2 1 Spindle and kinetochore-associated protein 1 DUF948 PF06103.11 EPS29397.1 - 0.017 15.4 1.6 2.2 8.6 0.1 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FliD_C PF07195.12 EPS29397.1 - 0.029 13.8 2.3 2 7.7 1.0 2.0 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus TolA_bind_tri PF16331.5 EPS29397.1 - 0.03 14.4 5.5 0.048 13.8 2.1 2.7 1 1 2 3 3 3 0 TolA binding protein trimerisation DUF2405 PF10293.9 EPS29397.1 - 0.033 14.1 1.2 0.11 12.4 0.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2405) AstE_AspA PF04952.14 EPS29397.1 - 0.034 13.2 0.4 0.036 13.1 0.4 1.2 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family UPF0242 PF06785.11 EPS29397.1 - 0.067 13.3 11.1 0.17 12.0 11.1 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus NPV_P10 PF05531.12 EPS29397.1 - 0.069 13.6 3.2 2.6 8.6 1.6 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein ALMS_motif PF15309.6 EPS29397.1 - 0.085 13.3 4.8 0.12 12.8 4.8 1.2 1 0 0 1 1 1 0 ALMS motif Y_phosphatase3 PF13350.6 EPS29397.1 - 0.091 12.7 1.4 0.12 12.3 1.4 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family ETF_alpha PF00766.19 EPS29397.1 - 0.099 12.7 0.7 0.3 11.1 0.0 1.9 2 0 0 2 2 2 0 Electron transfer flavoprotein FAD-binding domain Phage_holin_7_1 PF16081.5 EPS29397.1 - 0.15 12.2 1.7 1.9 8.7 0.1 2.1 1 1 1 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family Leu_zip PF15294.6 EPS29397.1 - 0.16 11.5 10.5 0.76 9.2 9.9 1.9 1 1 1 2 2 2 0 Leucine zipper Fib_alpha PF08702.10 EPS29397.1 - 0.19 11.9 5.2 0.31 11.2 5.0 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4407 PF14362.6 EPS29397.1 - 0.19 11.0 8.8 0.26 10.6 8.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BshC PF10079.9 EPS29397.1 - 0.21 10.3 7.2 0.25 10.1 7.2 1.2 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC FAM76 PF16046.5 EPS29397.1 - 0.25 10.7 6.3 0.28 10.5 6.3 1.1 1 0 0 1 1 1 0 FAM76 protein CREPT PF16566.5 EPS29397.1 - 0.26 11.4 8.2 0.32 11.1 6.0 1.8 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF4404 PF14357.6 EPS29397.1 - 0.31 11.7 8.6 0.68 10.6 0.9 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) Baculo_PEP_C PF04513.12 EPS29397.1 - 0.33 11.0 4.1 13 5.8 4.1 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mt_ATP-synt_D PF05873.12 EPS29397.1 - 0.37 10.6 7.2 0.43 10.4 2.4 2.1 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Fzo_mitofusin PF04799.13 EPS29397.1 - 0.42 10.2 6.2 2.1 7.8 0.9 2.1 1 1 1 2 2 2 0 fzo-like conserved region ADIP PF11559.8 EPS29397.1 - 0.43 10.6 10.2 0.49 10.5 6.8 2.1 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding SlyX PF04102.12 EPS29397.1 - 0.48 11.1 10.2 0.64 10.7 0.7 2.7 1 1 2 3 3 3 0 SlyX End3 PF12761.7 EPS29397.1 - 0.55 10.4 8.1 0.71 10.0 8.1 1.1 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 TPR_MLP1_2 PF07926.12 EPS29397.1 - 0.56 10.3 17.4 1.8 8.6 17.3 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Phage_Mu_Gam PF07352.12 EPS29397.1 - 0.61 10.0 14.3 0.86 9.5 4.8 2.2 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein Spectrin PF00435.21 EPS29397.1 - 0.63 10.6 11.9 0.51 10.8 8.0 2.4 1 1 1 2 2 2 0 Spectrin repeat Exonuc_VII_L PF02601.15 EPS29397.1 - 0.7 9.4 5.8 0.86 9.1 5.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3450 PF11932.8 EPS29397.1 - 0.81 8.9 13.2 4 6.7 10.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF1664 PF07889.12 EPS29397.1 - 0.87 9.6 5.4 5.4 7.1 5.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) TBCA PF02970.16 EPS29397.1 - 1.1 9.6 13.5 1.8 8.9 4.8 2.4 1 1 2 3 3 3 0 Tubulin binding cofactor A FapA PF03961.13 EPS29397.1 - 1.4 7.5 10.3 4.1 5.9 10.5 1.6 1 1 0 1 1 1 0 Flagellar Assembly Protein A DUF1690 PF07956.11 EPS29397.1 - 1.5 9.2 9.7 2.6 8.4 9.7 1.4 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) GrpE PF01025.19 EPS29397.1 - 1.8 8.2 15.3 0.58 9.8 5.6 2.1 1 1 1 2 2 2 0 GrpE DUF1366 PF07104.11 EPS29397.1 - 2.2 8.0 8.6 4.5 7.0 2.4 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1366) DUF4200 PF13863.6 EPS29397.1 - 3.2 8.2 17.0 4.9 7.6 8.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) TMPIT PF07851.13 EPS29397.1 - 3.4 6.8 8.4 8.8 5.5 8.4 1.7 1 1 0 1 1 1 0 TMPIT-like protein CCDC-167 PF15188.6 EPS29397.1 - 3.6 8.0 8.6 3.4 8.1 6.0 2.3 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 DUF2203 PF09969.9 EPS29397.1 - 4.9 7.9 10.1 7.7 7.3 4.5 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Ax_dynein_light PF10211.9 EPS29397.1 - 5.4 6.9 12.8 21 5.0 12.8 1.8 1 1 0 1 1 1 0 Axonemal dynein light chain YabA PF06156.13 EPS29397.1 - 5.7 7.6 9.4 13 6.5 2.0 2.4 1 1 1 2 2 2 0 Initiation control protein YabA COG2 PF06148.11 EPS29397.1 - 6.4 6.9 10.0 11 6.1 2.1 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 HalX PF08663.10 EPS29397.1 - 7.6 6.9 10.5 5.7 7.3 2.8 3.4 1 1 2 3 3 3 0 HalX domain Cep57_CLD_2 PF14197.6 EPS29398.1 - 0.063 13.4 0.0 0.084 13.0 0.0 1.2 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 ParE_toxin PF05016.15 EPS29398.1 - 0.15 12.7 0.1 0.2 12.3 0.1 1.1 1 0 0 1 1 1 0 ParE toxin of type II toxin-antitoxin system, parDE MscS_porin PF12795.7 EPS29399.1 - 0.007 15.9 0.8 0.0082 15.7 0.8 1.0 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain Telomere_reg-2 PF10193.9 EPS29400.1 - 0.0058 17.1 0.2 0.0071 16.8 0.2 1.1 1 0 0 1 1 1 1 Telomere length regulation protein Tropomyosin_1 PF12718.7 EPS29400.1 - 0.014 15.5 0.8 0.016 15.4 0.8 1.1 1 0 0 1 1 1 0 Tropomyosin like DUF4135 PF13575.6 EPS29400.1 - 0.14 11.4 0.0 0.15 11.4 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) DUF3311 PF11755.8 EPS29401.1 - 0.0036 17.2 0.0 0.0054 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3311) XRN_N PF03159.18 EPS29402.1 - 0.016 14.7 1.9 0.02 14.3 1.9 1.2 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus Peptidase_S9 PF00326.21 EPS29403.1 - 2.9e-51 173.9 0.2 5.8e-51 173.0 0.2 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family PD40 PF07676.12 EPS29403.1 - 5e-05 23.1 0.3 0.099 12.6 0.0 3.6 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Peptidase_S9_N PF02897.15 EPS29403.1 - 0.046 12.5 0.0 0.1 11.4 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain DNA_ligase_A_M PF01068.21 EPS29404.1 - 2.3e-60 203.7 0.8 1.6e-57 194.5 0.8 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EPS29404.1 - 2.5e-42 145.1 0.0 5.2e-42 144.1 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EPS29404.1 - 1.4e-28 99.3 0.0 4.4e-28 97.8 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 EPS29404.1 - 1.6e-05 25.3 0.3 2.5e-05 24.7 0.3 1.3 1 0 0 1 1 1 1 RNA ligase Adeno_E1B_55K_N PF04623.12 EPS29404.1 - 0.033 14.9 0.0 0.033 14.9 0.0 2.3 2 0 0 2 2 2 0 Adenovirus E1B protein N-terminus PI3K_1B_p101 PF10486.9 EPS29404.1 - 0.26 9.0 2.9 0.42 8.3 2.9 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Ndc1_Nup PF09531.10 EPS29404.1 - 1 8.0 4.8 1.4 7.5 4.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Macoilin PF09726.9 EPS29404.1 - 7.6 5.0 9.8 12 4.4 9.8 1.2 1 0 0 1 1 1 0 Macoilin family DUF4288 PF14119.6 EPS29406.1 - 0.13 12.7 0.0 0.15 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) His_Phos_2 PF00328.22 EPS29407.1 - 6.9e-38 131.0 0.0 8e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) EI24 PF07264.11 EPS29409.1 - 7.8e-11 42.5 0.9 1.2e-10 41.9 0.9 1.3 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF3237 PF11578.8 EPS29410.1 - 7.1e-22 77.8 0.3 4.7e-16 59.0 0.2 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3237) eIF-5_eIF-2B PF01873.17 EPS29411.1 - 1.6e-39 134.4 0.0 3.5e-39 133.3 0.0 1.6 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 EPS29411.1 - 1.6e-22 79.4 0.2 5.1e-22 77.8 0.2 1.9 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon DUF1754 PF08555.10 EPS29411.1 - 6 7.7 16.7 0.32 11.8 10.7 2.1 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) HK PF02110.15 EPS29412.1 - 5.1e-73 245.5 0.0 1.2e-72 244.2 0.0 1.6 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 EPS29412.1 - 4.1e-60 202.2 2.6 6.6e-60 201.5 2.6 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase Carb_kinase PF01256.17 EPS29412.1 - 0.00096 18.7 0.0 0.0023 17.5 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate kinase NMO PF03060.15 EPS29412.1 - 0.0018 17.7 2.5 0.003 17.0 2.5 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase Phos_pyr_kin PF08543.12 EPS29412.1 - 0.019 14.4 0.5 0.23 10.8 0.0 2.8 2 2 1 3 3 3 0 Phosphomethylpyrimidine kinase Isochorismatase PF00857.20 EPS29413.1 - 9.8e-30 104.0 0.1 1.2e-29 103.7 0.1 1.1 1 0 0 1 1 1 1 Isochorismatase family Lipase_GDSL_2 PF13472.6 EPS29415.1 - 1e-27 97.7 0.1 2e-27 96.8 0.1 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EPS29415.1 - 5.9e-19 68.8 0.0 8.1e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Voltage_CLC PF00654.20 EPS29416.1 - 3.5e-90 302.8 21.8 3.5e-90 302.8 21.8 2.0 2 0 0 2 2 2 1 Voltage gated chloride channel PqiA PF04403.13 EPS29416.1 - 5.5e-05 23.1 2.2 0.00011 22.1 1.1 2.1 2 0 0 2 2 2 1 Paraquat-inducible protein A adh_short_C2 PF13561.6 EPS29417.1 - 7.4e-61 205.7 0.5 9.4e-61 205.3 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPS29417.1 - 8.1e-50 169.0 0.8 1.1e-49 168.6 0.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPS29417.1 - 5.7e-12 45.9 0.2 9.7e-12 45.1 0.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPS29417.1 - 0.00037 20.0 0.2 0.001 18.6 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EPS29417.1 - 0.017 14.2 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DHFR_1 PF00186.19 EPS29418.1 - 1.7e-16 60.3 0.0 3.4e-12 46.3 0.0 2.7 2 1 0 2 2 2 2 Dihydrofolate reductase Eno-Rase_NADH_b PF12242.8 EPS29418.1 - 0.11 12.2 0.1 0.3 10.9 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Med22 PF06179.12 EPS29419.1 - 7.1e-20 71.2 1.1 9.1e-20 70.8 1.1 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex RNase_3_N PF18497.1 EPS29419.1 - 0.065 13.5 0.2 0.084 13.1 0.2 1.2 1 0 0 1 1 1 0 Ribonuclease III N-terminal domain CTK3_C PF12350.8 EPS29419.1 - 0.64 10.2 5.0 0.17 12.0 0.8 2.2 2 1 1 3 3 3 0 CTD kinase subunit gamma CTK3 C-terminus Cwf_Cwc_15 PF04889.12 EPS29420.1 - 4.2e-87 292.0 19.5 4.8e-87 291.8 19.5 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Merozoite_SPAM PF07133.11 EPS29420.1 - 0.13 12.3 20.4 0.19 11.7 20.4 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) PA26 PF04636.13 EPS29420.1 - 0.55 9.1 4.5 0.61 8.9 4.5 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF3752 PF12572.8 EPS29420.1 - 0.72 10.4 20.9 1.1 9.8 20.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3752) Roughex PF06020.11 EPS29420.1 - 2.5 7.1 14.9 3.4 6.7 14.9 1.1 1 0 0 1 1 1 0 Drosophila roughex protein CDC45 PF02724.14 EPS29420.1 - 4.2 5.5 18.8 5.2 5.2 18.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Coilin_N PF15862.5 EPS29420.1 - 6.2 6.6 13.0 14 5.4 13.0 1.6 1 0 0 1 1 1 0 Coilin N-terminus RNase_PH PF01138.21 EPS29421.1 - 1.9e-18 67.2 0.0 3.1e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EPS29421.1 - 5.8e-06 26.3 0.0 1e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 PhoLip_ATPase_C PF16212.5 EPS29422.1 - 3.3e-81 272.7 20.2 3.3e-81 272.7 20.2 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EPS29422.1 - 8.2e-26 89.5 8.1 8.2e-26 89.5 8.1 2.0 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EPS29422.1 - 4.8e-13 49.9 0.1 2.9e-12 47.3 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EPS29422.1 - 1.1e-11 44.6 0.0 3.7e-11 43.0 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EPS29422.1 - 1.2e-05 24.9 0.0 3e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EPS29422.1 - 0.0066 16.2 0.0 0.02 14.6 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DNA_pol_B_thumb PF14791.6 EPS29423.1 - 4e-21 74.9 0.3 2.6e-20 72.3 0.6 2.2 3 0 0 3 3 3 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 EPS29423.1 - 1.9e-18 66.0 0.4 3.7e-18 65.1 0.4 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.6 EPS29423.1 - 3.3e-16 59.5 0.2 8.2e-16 58.2 0.2 1.6 1 1 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.6 EPS29423.1 - 9e-09 35.6 0.1 2.1e-08 34.4 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.6 EPS29423.1 - 0.025 15.2 0.0 0.14 12.7 0.0 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 EPS29423.1 - 0.049 13.9 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain NicO PF03824.16 EPS29424.1 - 9.8e-59 199.0 22.2 5.1e-58 196.7 5.7 2.4 3 0 0 3 3 3 2 High-affinity nickel-transport protein GMC_oxred_N PF00732.19 EPS29427.1 - 2.4e-52 178.2 0.0 3.1e-52 177.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EPS29427.1 - 1e-31 110.4 0.1 1.7e-31 109.7 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EPS29427.1 - 9.1e-05 21.7 0.0 0.00013 21.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 EPS29427.1 - 0.00019 21.1 0.0 0.072 12.7 0.0 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPS29427.1 - 0.0026 17.0 0.0 0.032 13.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPS29427.1 - 0.0032 17.7 0.1 0.013 15.7 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EPS29427.1 - 0.0049 16.2 0.0 1.4 8.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EPS29427.1 - 0.025 13.6 0.1 2 7.4 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EPS29427.1 - 0.076 12.1 0.0 0.31 10.1 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain ApbA_C PF08546.11 EPS29427.1 - 0.13 12.5 0.0 1.4 9.1 0.0 2.5 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA C terminal HI0933_like PF03486.14 EPS29427.1 - 0.16 10.7 0.0 2 7.0 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Mur_ligase_M PF08245.12 EPS29428.1 - 0.0001 22.4 0.0 0.00025 21.1 0.0 1.6 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 EPS29428.1 - 0.002 18.4 0.0 0.004 17.4 0.0 1.5 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain HAD_2 PF13419.6 EPS29429.1 - 9.5e-25 87.7 0.0 1.2e-24 87.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EPS29429.1 - 4.4e-12 46.7 0.5 6.6e-11 42.9 0.5 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EPS29429.1 - 9.4e-11 42.5 0.0 1.3e-10 42.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EPS29429.1 - 4.7e-09 36.2 0.0 1.1e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EPS29429.1 - 4.7e-05 23.4 0.0 0.0068 16.5 0.0 2.4 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EPS29429.1 - 0.041 13.6 0.0 0.68 9.6 0.0 2.3 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 EPS29429.1 - 0.14 11.7 0.1 0.32 10.6 0.0 1.8 1 1 0 1 1 1 0 Mitochondrial PGP phosphatase Glyco_hydro_71 PF03659.14 EPS29432.1 - 2.9e-140 467.4 6.8 2.9e-140 467.4 6.8 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 71 PAN_1 PF00024.26 EPS29434.1 - 1.2e-05 25.2 0.2 1.7e-05 24.7 0.2 1.4 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 EPS29434.1 - 0.0082 16.0 0.5 0.015 15.2 0.5 1.4 1 0 0 1 1 1 1 PAN domain Herpes_UL21 PF03252.13 EPS29435.1 - 0.062 12.0 0.0 0.094 11.5 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL21 Pkinase PF00069.25 EPS29436.1 - 6.8e-23 81.4 0.0 7.7e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS29436.1 - 1.9e-19 70.0 0.0 2.9e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EPS29436.1 - 0.00069 19.0 0.0 0.001 18.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EPS29436.1 - 0.033 13.8 0.0 0.044 13.4 0.0 1.2 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 EPS29436.1 - 0.041 13.8 0.0 0.058 13.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pyridox_oxase_2 PF12766.7 EPS29437.1 - 1.1e-27 96.6 0.0 1.7e-27 95.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Las1 PF04031.13 EPS29438.1 - 4.1e-48 163.4 0.3 7.9e-48 162.5 0.1 1.6 2 0 0 2 2 2 1 Las1-like Lactamase_B PF00753.27 EPS29439.1 - 3.2e-21 76.2 0.4 8.4e-20 71.6 0.4 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily HAGH_C PF16123.5 EPS29439.1 - 9.8e-21 74.1 0.2 1.6e-20 73.3 0.2 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B_2 PF12706.7 EPS29439.1 - 3.5e-05 23.4 0.9 0.00046 19.8 0.8 2.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EPS29439.1 - 0.0023 17.9 0.1 0.0059 16.5 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain BcrAD_BadFG PF01869.20 EPS29439.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.5 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DUF1275 PF06912.11 EPS29440.1 - 2e-47 161.6 10.2 2.3e-47 161.4 10.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF1422 PF07226.11 EPS29440.1 - 0.0088 16.0 1.8 0.19 11.7 0.8 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1422) WD40 PF00400.32 EPS29442.1 - 6.3e-43 143.9 12.1 1.4e-06 28.9 0.0 8.2 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.7 EPS29442.1 - 2.4e-13 49.7 0.5 4.7e-13 48.8 0.5 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 EPS29442.1 - 2.8e-10 39.5 4.8 0.024 13.3 0.1 5.1 3 1 2 5 5 5 5 Nucleoporin Nup120/160 F-box PF00646.33 EPS29442.1 - 5.3e-10 38.9 0.1 1.3e-09 37.7 0.1 1.7 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 EPS29442.1 - 3.8e-05 23.9 0.1 0.092 13.1 0.0 3.9 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 EPS29442.1 - 0.0015 18.4 0.1 0.013 15.4 0.0 2.5 2 0 0 2 2 2 1 F-box WD40_like PF17005.5 EPS29442.1 - 0.094 12.0 0.0 0.31 10.3 0.0 1.8 1 1 0 1 1 1 0 WD40-like domain Mannosyl_trans3 PF11051.8 EPS29443.1 - 0.14 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative YafO_toxin PF13957.6 EPS29443.1 - 0.17 11.9 0.1 0.4 10.8 0.1 1.5 1 0 0 1 1 1 0 Toxin YafO, type II toxin-antitoxin system Peptidase_M20 PF01546.28 EPS29444.1 - 2.2e-21 76.5 0.1 3.4e-21 75.9 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EPS29444.1 - 1e-13 51.1 0.1 3e-13 49.6 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain Glyco_hydro_16 PF00722.21 EPS29445.1 - 1.7e-06 27.6 0.0 3.7e-06 26.5 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 CNPase PF05881.12 EPS29445.1 - 0.032 13.8 0.0 0.054 13.1 0.0 1.3 1 0 0 1 1 1 0 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) TrkH PF02386.16 EPS29446.1 - 2.7e-148 494.5 5.6 2.7e-148 494.5 5.6 2.0 2 0 0 2 2 2 2 Cation transport protein Zn_clus PF00172.18 EPS29447.1 - 1.7e-07 31.2 10.3 1.7e-07 31.2 10.3 2.1 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPS29447.1 - 4.9e-05 22.5 0.0 0.0001 21.5 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain RGS PF00615.19 EPS29448.1 - 0.0023 18.2 0.0 0.0044 17.3 0.0 1.4 1 0 0 1 1 1 1 Regulator of G protein signaling domain CAP59_mtransfer PF11735.8 EPS29451.1 - 6.7e-75 251.9 0.0 8.6e-75 251.5 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 IF-2B PF01008.17 EPS29452.1 - 3.2e-70 236.6 0.3 3.7e-70 236.4 0.3 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family PQQ_3 PF13570.6 EPS29454.1 - 0.0062 17.0 0.5 1.3 9.6 0.1 2.9 2 0 0 2 2 2 2 PQQ-like domain Rhomboid PF01694.22 EPS29455.1 - 1.3e-21 77.2 8.1 1.3e-21 77.2 8.1 1.6 2 0 0 2 2 2 1 Rhomboid family Metallophos PF00149.28 EPS29456.1 - 5e-08 33.7 1.4 8.3e-08 33.0 1.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Med19 PF10278.9 EPS29456.1 - 7 6.5 12.0 3.6 7.5 1.6 2.3 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 Importin_rep_3 PF18806.1 EPS29457.1 - 5.2e-07 29.6 0.0 5.2e-06 26.4 0.0 2.6 2 0 0 2 2 2 1 Importin 13 repeat Importin_rep PF18773.1 EPS29457.1 - 7.7e-07 28.7 0.1 1.3e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 Importin 13 repeat EH_Signature PF15611.6 EPS29457.1 - 0.068 12.6 2.8 0.043 13.2 0.6 1.7 2 0 0 2 2 2 0 EH_Signature domain PKD PF00801.20 EPS29457.1 - 0.15 11.9 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 PKD domain Sec7_N PF12783.7 EPS29457.1 - 1.3 8.9 5.4 0.27 11.1 0.2 2.6 3 0 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal FAD_binding_3 PF01494.19 EPS29458.1 - 1.3e-81 274.6 0.0 2.7e-79 267.0 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EPS29458.1 - 2.7e-33 115.3 0.0 5.1e-33 114.5 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_2 PF00890.24 EPS29458.1 - 0.00016 20.9 0.2 0.00024 20.3 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EPS29458.1 - 0.00018 20.4 0.1 0.00032 19.5 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 EPS29458.1 - 0.00029 20.2 0.0 0.00047 19.5 0.0 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 EPS29458.1 - 0.0016 18.7 0.1 0.004 17.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EPS29458.1 - 0.002 17.4 0.1 0.0053 16.0 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EPS29458.1 - 0.0039 16.6 0.1 0.0057 16.1 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 EPS29458.1 - 0.01 15.5 0.1 0.025 14.2 0.1 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 EPS29458.1 - 0.01 14.9 0.1 0.015 14.4 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EPS29458.1 - 0.036 13.3 0.0 0.059 12.6 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EPS29458.1 - 0.12 11.6 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Zn_clus PF00172.18 EPS29459.1 - 1.2e-10 41.4 10.2 2.1e-10 40.6 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPS29459.1 - 1.9e-06 27.1 1.4 3.2e-06 26.4 0.3 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Glyco_transf_90 PF05686.12 EPS29460.1 - 2.2e-34 119.1 0.0 3.2e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 EPS29460.1 - 0.0015 18.9 0.0 0.0028 18.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Amidohydro_1 PF01979.20 EPS29461.1 - 1.2e-61 208.9 0.0 3.8e-52 177.7 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 EPS29461.1 - 7.1e-06 25.7 1.2 0.0015 18.1 0.0 2.8 2 1 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 EPS29461.1 - 0.0082 15.5 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Toxin_29 PF08116.11 EPS29461.1 - 0.08 12.9 0.5 0.15 12.1 0.5 1.4 1 0 0 1 1 1 0 PhTx neurotoxin family Fungal_trans PF04082.18 EPS29462.1 - 1.3e-16 60.4 0.0 2.3e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS29462.1 - 6.3e-07 29.4 8.9 1.2e-06 28.6 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.21 EPS29464.1 - 3.7e-74 250.3 0.0 5.1e-74 249.8 0.0 1.1 1 0 0 1 1 1 1 Amidase Isochorismatase PF00857.20 EPS29464.1 - 1.6e-41 142.4 0.1 3.9e-41 141.1 0.0 1.7 2 0 0 2 2 2 1 Isochorismatase family Transp_cyt_pur PF02133.15 EPS29465.1 - 7.8e-96 321.5 41.7 9.8e-96 321.2 41.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin ACC_central PF08326.12 EPS29466.1 - 4.9e-283 940.9 0.0 6.2e-283 940.5 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 EPS29466.1 - 7.9e-191 635.0 0.0 1.2e-190 634.4 0.0 1.3 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 EPS29466.1 - 2.3e-51 174.3 0.0 4.4e-51 173.4 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EPS29466.1 - 4.5e-28 98.0 0.1 9.2e-28 97.0 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EPS29466.1 - 2.9e-23 82.0 0.0 9.9e-20 70.7 0.0 3.7 4 0 0 4 4 4 2 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EPS29466.1 - 5.5e-18 64.6 0.2 1.4e-17 63.2 0.1 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 EPS29466.1 - 0.0012 19.0 0.0 0.0035 17.4 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EPS29466.1 - 0.004 16.7 0.0 0.01 15.4 0.0 1.7 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus GxGYxYP_N PF16216.5 EPS29466.1 - 0.074 13.2 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function N-terminal ATPgrasp_Ter PF15632.6 EPS29466.1 - 0.11 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.6 EPS29466.1 - 0.15 11.9 0.0 0.46 10.4 0.0 1.8 1 0 0 1 1 1 0 Biotin-lipoyl like R3H-assoc PF13902.6 EPS29466.1 - 0.22 11.9 0.9 0.56 10.6 0.5 1.8 2 0 0 2 2 2 0 R3H-associated N-terminal domain NUDE_C PF04880.13 EPS29469.1 - 2.4e-66 223.6 3.5 2.4e-66 223.6 3.5 4.5 2 1 2 4 4 2 1 NUDE protein, C-terminal conserved region ZapB PF06005.12 EPS29469.1 - 0.00027 21.3 6.0 0.00027 21.3 6.0 4.7 2 1 3 5 5 5 1 Cell division protein ZapB BAR_2 PF10455.9 EPS29469.1 - 0.017 14.3 8.3 0.029 13.5 8.3 1.3 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking PSII_Pbs27 PF13326.6 EPS29469.1 - 0.04 14.2 3.8 0.091 13.1 3.8 1.6 1 0 0 1 1 1 0 Photosystem II Pbs27 Golgin_A5 PF09787.9 EPS29469.1 - 0.12 11.8 18.2 0.25 10.8 18.2 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 ERM PF00769.19 EPS29469.1 - 0.13 12.1 24.3 0.27 11.0 24.3 1.5 1 0 0 1 1 1 0 Ezrin/radixin/moesin family ATG16 PF08614.11 EPS29469.1 - 0.18 12.0 32.6 0.04 14.1 14.1 3.1 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) LPP PF04728.13 EPS29469.1 - 0.5 10.8 3.5 1.6 9.2 0.4 3.1 3 1 0 3 3 3 0 Lipoprotein leucine-zipper Tropomyosin_1 PF12718.7 EPS29469.1 - 0.99 9.6 30.1 1.8 8.7 22.4 3.3 2 1 1 3 3 3 0 Tropomyosin like Filament PF00038.21 EPS29469.1 - 1 8.9 26.2 3.6 7.1 6.0 2.2 1 1 1 2 2 2 0 Intermediate filament protein DUF4407 PF14362.6 EPS29469.1 - 1.4 8.2 11.7 2.2 7.5 11.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GrpE PF01025.19 EPS29469.1 - 1.7 8.3 19.0 0.12 12.0 12.7 2.2 1 1 1 2 2 2 0 GrpE Fez1 PF06818.15 EPS29469.1 - 2.6 8.5 24.6 2.2 8.7 9.3 2.7 2 1 1 3 3 3 0 Fez1 DUF812 PF05667.11 EPS29469.1 - 3.1 6.6 19.4 4.7 6.0 19.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF745 PF05335.13 EPS29469.1 - 3.3 7.4 7.0 4.5 6.9 5.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF745) Fmp27_WPPW PF10359.9 EPS29469.1 - 3.4 6.4 16.5 1.3 7.8 13.0 1.8 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain ADIP PF11559.8 EPS29469.1 - 4.2 7.5 27.1 2.2 8.3 1.6 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding Uso1_p115_C PF04871.13 EPS29469.1 - 7 7.0 25.2 1.7 9.0 1.1 2.8 2 1 0 3 3 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Chibby PF14645.6 EPS29469.1 - 8.6 6.8 12.8 12 6.3 8.3 2.5 1 1 1 2 2 2 0 Chibby family Exonuc_VII_L PF02601.15 EPS29469.1 - 9.3 5.7 10.7 19 4.7 10.7 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Isochorismatase PF00857.20 EPS29470.1 - 1.6e-42 145.6 0.0 4.2e-42 144.3 0.0 1.7 2 0 0 2 2 2 1 Isochorismatase family FAR1 PF03101.15 EPS29470.1 - 2.7e-05 24.8 0.0 5.2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.11 EPS29470.1 - 0.018 15.4 0.0 0.033 14.6 0.0 1.3 1 0 0 1 1 1 0 Transcription factor AFT Sedlin_N PF04628.13 EPS29471.1 - 2.8e-43 147.2 0.0 3.2e-43 147.0 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 EPS29471.1 - 0.00043 20.2 0.0 0.0031 17.5 0.0 1.9 2 0 0 2 2 2 1 Sybindin-like family DUF2040 PF09745.9 EPS29472.1 - 1.2e-38 131.8 19.0 1.2e-38 131.8 19.0 4.3 4 1 1 5 5 5 1 Coiled-coil domain-containing protein 55 (DUF2040) BON PF04972.17 EPS29472.1 - 0.039 14.3 0.1 0.14 12.5 0.1 2.0 1 0 0 1 1 1 0 BON domain Ribosomal_S30 PF04758.14 EPS29473.1 - 2.3e-28 98.2 5.5 2.5e-28 98.0 5.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 NACHT PF05729.12 EPS29475.1 - 7.3e-07 29.3 0.1 3.2e-06 27.2 0.1 2.1 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EPS29475.1 - 8.2e-07 29.6 0.1 5.1e-05 23.7 0.0 3.4 2 0 0 2 2 2 1 AAA ATPase domain TPR_12 PF13424.6 EPS29475.1 - 5.5e-06 26.6 15.1 0.19 12.1 0.0 8.8 11 0 0 11 11 11 1 Tetratricopeptide repeat AAA_22 PF13401.6 EPS29475.1 - 3.1e-05 24.3 0.0 0.00022 21.5 0.0 2.5 1 1 1 2 2 2 1 AAA domain TPR_7 PF13176.6 EPS29475.1 - 0.00014 21.6 11.6 1.1 9.5 0.0 7.4 7 0 0 7 7 7 1 Tetratricopeptide repeat NB-ARC PF00931.22 EPS29475.1 - 0.00022 20.5 0.2 0.00063 19.0 0.2 1.7 1 0 0 1 1 1 1 NB-ARC domain TPR_14 PF13428.6 EPS29475.1 - 0.0018 18.9 7.8 24 6.1 0.1 7.0 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_19 PF14559.6 EPS29475.1 - 0.01 16.3 5.5 0.15 12.6 0.1 4.6 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 EPS29475.1 - 0.15 12.8 0.3 15 6.6 0.1 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 EPS29475.1 - 5 7.1 12.6 5.2 7.1 0.1 6.7 9 0 0 9 9 9 0 Tetratricopeptide repeat SIMPL PF04402.14 EPS29476.1 - 4.8e-43 148.0 0.3 5.5e-43 147.7 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Zip PF02535.22 EPS29477.1 - 4.7e-27 95.1 6.3 8.3e-17 61.4 4.4 2.2 2 0 0 2 2 2 2 ZIP Zinc transporter Tetraspanin PF00335.20 EPS29477.1 - 0.2 11.3 1.2 0.34 10.6 0.0 1.9 2 0 0 2 2 2 0 Tetraspanin family DUF2975 PF11188.8 EPS29477.1 - 0.36 10.7 7.9 0.11 12.3 3.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) Endonuclease_NS PF01223.23 EPS29478.1 - 3.1e-65 220.2 0.0 3.8e-65 219.9 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease zf-RING_UBOX PF13445.6 EPS29479.1 - 4.6e-07 29.7 8.5 3.2e-05 23.9 3.2 2.8 2 1 0 2 2 2 2 RING-type zinc-finger zf-NOSIP PF15906.5 EPS29479.1 - 0.00014 22.0 0.0 0.00031 20.8 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-C3HC4_2 PF13923.6 EPS29479.1 - 0.00021 21.1 10.7 0.00039 20.2 3.6 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EPS29479.1 - 0.00026 21.2 11.5 0.012 15.9 5.1 2.9 2 1 0 2 2 2 2 Ring finger domain zf-C3HC4 PF00097.25 EPS29479.1 - 0.00044 20.0 2.4 0.00044 20.0 2.4 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EPS29479.1 - 0.00059 19.7 5.5 0.00059 19.7 5.5 2.8 2 2 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EPS29479.1 - 0.00098 18.9 13.2 0.005 16.7 2.4 3.3 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 EPS29479.1 - 0.015 15.4 10.6 0.062 13.4 3.9 3.1 1 1 1 2 2 2 0 FYVE zinc finger zf-C3HC4_5 PF17121.5 EPS29479.1 - 0.048 13.6 2.1 0.14 12.1 2.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4407 PF14362.6 EPS29479.1 - 3.5 6.9 12.1 1.3 8.3 7.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) IBR PF01485.21 EPS29479.1 - 4.2 7.7 8.0 6.5 7.1 0.5 3.0 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain zf-C3HC4_4 PF15227.6 EPS29479.1 - 6.1 7.1 12.7 0.49 10.6 2.0 3.1 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING Sec7 PF01369.20 EPS29480.1 - 1e-33 116.6 0.0 1.7e-33 115.8 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.6 EPS29480.1 - 6.9e-07 29.7 0.1 1.4e-06 28.7 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EPS29480.1 - 2e-06 28.2 0.1 5.1e-06 26.9 0.1 1.7 1 0 0 1 1 1 1 PH domain DUF3439 PF11921.8 EPS29480.1 - 7.6 6.5 6.8 20 5.2 6.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Peptidase_M14 PF00246.24 EPS29481.1 - 6.2e-82 275.6 0.0 7.9e-82 275.3 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase AA_permease PF00324.21 EPS29482.1 - 5.3e-128 427.6 33.8 6.6e-128 427.3 33.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EPS29482.1 - 1.2e-33 116.6 37.8 1.5e-33 116.3 37.8 1.2 1 0 0 1 1 1 1 Amino acid permease Na_Ala_symp PF01235.17 EPS29482.1 - 0.04 13.2 13.2 0.63 9.3 4.1 2.5 2 0 0 2 2 2 0 Sodium:alanine symporter family AMP-binding PF00501.28 EPS29486.1 - 3.7e-24 85.1 0.0 5.6e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EPS29486.1 - 2.3e-21 76.1 0.0 3.8e-15 55.8 0.0 2.3 1 1 1 2 2 2 2 Male sterility protein PP-binding PF00550.25 EPS29486.1 - 2.1e-10 40.8 0.2 4.1e-10 39.9 0.2 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 EPS29486.1 - 0.034 13.6 0.0 1.5 8.2 0.0 2.5 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EPS29488.1 - 4.5e-34 117.8 0.0 8.1e-34 116.9 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EPS29488.1 - 6.2e-19 67.9 0.1 6.4e-15 54.7 0.0 3.4 3 1 0 4 4 4 2 AMP-binding enzyme Epimerase PF01370.21 EPS29488.1 - 4.6e-10 39.4 0.0 7e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EPS29488.1 - 1.9e-05 24.2 0.0 4.8e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase PP-binding PF00550.25 EPS29488.1 - 0.00012 22.4 0.0 0.0003 21.1 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site FSH1 PF03959.13 EPS29489.1 - 2.8e-25 89.2 0.0 1.3e-24 87.1 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) ADH_zinc_N PF00107.26 EPS29490.1 - 1.1e-09 38.4 0.2 3.6e-09 36.7 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPS29490.1 - 1.5e-05 24.8 2.6 4.2e-05 23.4 2.2 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ketoacyl-synt PF00109.26 EPS29491.1 - 4.1e-74 249.4 0.0 9.4e-74 248.2 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EPS29491.1 - 5.8e-55 186.0 0.1 1.2e-54 184.9 0.1 1.6 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 EPS29491.1 - 1.2e-50 172.5 0.3 2.6e-50 171.3 0.0 1.8 2 0 0 2 2 2 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 EPS29491.1 - 7.8e-49 166.9 0.1 1.4e-48 166.1 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EPS29491.1 - 8.3e-33 112.9 0.3 3.2e-32 111.0 0.1 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EPS29491.1 - 7.7e-17 61.8 0.0 2.2e-16 60.3 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension adh_short PF00106.25 EPS29491.1 - 6.6e-13 48.6 0.3 2.3e-12 46.8 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS29491.1 - 5.3e-07 29.4 0.1 1.2e-06 28.3 0.1 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase PP-binding PF00550.25 EPS29491.1 - 1.8e-06 28.2 0.1 1.2e-05 25.5 0.1 2.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 EPS29491.1 - 0.00017 21.0 0.0 0.00035 20.0 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.10 EPS29491.1 - 0.0051 16.6 0.1 0.062 13.2 0.2 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ADH_zinc_N PF00107.26 EPS29491.1 - 0.016 15.2 0.0 0.071 13.1 0.0 2.2 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Semialdhyde_dh PF01118.24 EPS29491.1 - 0.13 12.7 0.1 0.4 11.1 0.1 1.9 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Abhydrolase_3 PF07859.13 EPS29492.1 - 6.8e-11 42.4 0.7 3.5e-08 33.6 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EPS29492.1 - 9.8e-10 38.3 0.1 0.00012 21.6 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 EPS29492.1 - 3.6e-05 22.8 0.0 5.9e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 EPS29492.1 - 7e-05 22.0 0.0 0.0001 21.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_2 PF02230.16 EPS29492.1 - 0.00022 21.1 0.6 0.75 9.6 0.0 2.7 2 1 1 3 3 3 2 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 EPS29492.1 - 0.00039 20.1 0.1 0.0071 16.0 0.1 2.5 2 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.18 EPS29492.1 - 0.0025 17.4 0.0 0.15 11.6 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family AXE1 PF05448.12 EPS29492.1 - 0.0033 16.1 0.1 0.3 9.7 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 EPS29492.1 - 0.01 15.2 0.5 0.049 12.9 0.1 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DUF829 PF05705.14 EPS29492.1 - 0.13 12.1 0.0 0.3 10.9 0.0 1.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF829) F-box_4 PF15966.5 EPS29494.1 - 0.002 18.0 1.8 0.021 14.7 0.0 3.1 4 0 0 4 4 4 1 F-box F-box-like PF12937.7 EPS29494.1 - 0.0033 17.3 0.0 0.0089 15.9 0.0 1.8 1 0 0 1 1 1 1 F-box-like PP-binding PF00550.25 EPS29496.1 - 1.8e-06 28.2 0.1 2.7e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site HTH_51 PF18558.1 EPS29496.1 - 0.00011 21.9 0.0 0.00022 21.0 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Cation_ATPase_C PF00689.21 EPS29497.1 - 4.5e-37 127.5 3.1 4.5e-37 127.5 3.1 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EPS29497.1 - 2.4e-36 124.9 0.8 2.4e-36 124.9 0.8 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EPS29497.1 - 2.9e-22 80.0 0.1 1.4e-09 38.5 0.2 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EPS29497.1 - 5.9e-15 55.1 0.0 1.1e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EPS29497.1 - 9e-13 47.7 0.0 2.1e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EPS29497.1 - 7.6e-05 22.6 0.1 0.00017 21.5 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Bac_rhodopsin PF01036.18 EPS29498.1 - 2.3e-60 204.0 18.3 2.6e-60 203.8 18.3 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein MazE_antitoxin PF04014.18 EPS29498.1 - 0.03 14.2 0.0 0.058 13.4 0.0 1.4 1 0 0 1 1 1 0 Antidote-toxin recognition MazE, bacterial antitoxin DUF21 PF01595.20 EPS29498.1 - 0.15 11.8 3.5 0.3 10.8 3.5 1.5 1 0 0 1 1 1 0 Cyclin M transmembrane N-terminal domain DUF4131 PF13567.6 EPS29498.1 - 0.57 9.8 5.1 0.18 11.4 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF1772 PF08592.11 EPS29498.1 - 2.8 8.3 6.9 1.4 9.2 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) Zn_peptidase_2 PF04298.12 EPS29498.1 - 8 5.8 7.7 0.26 10.7 0.3 2.0 2 0 0 2 2 2 0 Putative neutral zinc metallopeptidase RPE65 PF03055.15 EPS29500.1 - 4.6e-108 362.4 0.0 5.3e-108 362.2 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein dCMP_cyt_deam_1 PF00383.23 EPS29501.1 - 0.00011 22.0 0.0 0.00014 21.7 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 EPS29501.1 - 0.025 14.2 1.2 1.2 8.7 1.2 2.4 1 1 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases Aldo_ket_red PF00248.21 EPS29502.1 - 6.3e-73 245.5 0.0 7.1e-73 245.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Phage_terminase PF10668.9 EPS29502.1 - 0.16 12.0 0.1 0.36 10.9 0.1 1.5 1 0 0 1 1 1 0 Phage terminase small subunit Oxidored_molyb PF00174.19 EPS29503.1 - 1.3e-55 187.7 0.0 1.8e-55 187.2 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EPS29503.1 - 4.7e-26 91.4 0.1 9.3e-26 90.5 0.1 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 EPS29503.1 - 2.8e-12 46.6 0.0 4.5e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Alpha-amylase PF00128.24 EPS29504.1 - 7.7e-117 390.6 1.5 1.3e-116 389.9 1.5 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 EPS29504.1 - 2.7e-09 37.0 0.0 7.3e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 Maltogenic Amylase, C-terminal domain Alpha-amylase_C PF02806.18 EPS29504.1 - 0.00033 21.1 0.1 0.0019 18.6 0.0 2.3 1 1 1 2 2 2 1 Alpha amylase, C-terminal all-beta domain DUF3459 PF11941.8 EPS29504.1 - 0.023 15.0 0.0 0.05 13.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) DUF1780 PF08682.10 EPS29504.1 - 0.064 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative endonuclease, protein of unknown function (DUF1780) Fungal_trans PF04082.18 EPS29505.1 - 3.2e-06 26.4 0.0 5.3e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 EPS29506.1 - 3.9e-23 81.9 21.9 5.6e-23 81.4 21.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TauD PF02668.16 EPS29507.1 - 4.2e-53 180.8 0.0 5.7e-53 180.4 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF4461 PF14688.6 EPS29507.1 - 0.072 12.9 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4461) TRI5 PF06330.11 EPS29508.1 - 0.1 11.4 0.1 0.28 10.0 0.1 1.7 1 1 0 1 1 1 0 Trichodiene synthase (TRI5) Glyco_hydro_28 PF00295.17 EPS29509.1 - 1.5e-97 326.6 12.1 1.5e-97 326.6 12.1 2.1 3 0 0 3 3 3 1 Glycosyl hydrolases family 28 Pectinesterase PF01095.19 EPS29509.1 - 5.9e-43 146.7 0.5 1.7e-42 145.2 0.5 1.8 2 0 0 2 2 2 1 Pectinesterase Sulfatase PF00884.23 EPS29510.1 - 2.6e-65 220.8 0.5 3.8e-65 220.3 0.5 1.2 1 0 0 1 1 1 1 Sulfatase DUF4976 PF16347.5 EPS29510.1 - 0.00042 20.5 0.1 0.00093 19.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) Phosphodiest PF01663.22 EPS29510.1 - 0.00079 19.1 2.2 0.004 16.8 2.3 1.8 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Antimicrobial18 PF08130.11 EPS29510.1 - 0.088 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Type A lantibiotic family Fungal_trans PF04082.18 EPS29511.1 - 1.5e-19 70.0 0.0 1.6e-18 66.7 0.0 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS29511.1 - 3.4e-09 36.7 10.8 6.5e-09 35.8 10.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_7 PF03441.14 EPS29512.1 - 1.5e-77 259.7 0.5 2.2e-77 259.1 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EPS29512.1 - 1.1e-39 136.1 0.1 2e-39 135.3 0.1 1.4 1 0 0 1 1 1 1 DNA photolyase Aminotran_4 PF01063.19 EPS29515.1 - 9.3e-25 87.8 0.0 1.1e-24 87.5 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Pkinase PF00069.25 EPS29517.1 - 1.6e-42 145.7 0.0 1.5e-41 142.5 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.12 EPS29517.1 - 7.7e-39 132.8 0.0 1.8e-38 131.6 0.0 1.7 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 EPS29517.1 - 3.3e-21 75.7 0.0 1.5e-20 73.6 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ PF01011.21 EPS29517.1 - 0.00062 19.6 0.0 0.49 10.4 0.0 3.0 2 0 0 2 2 2 2 PQQ enzyme repeat PQQ_2 PF13360.6 EPS29517.1 - 0.0007 19.3 0.2 0.0069 16.0 0.1 2.2 2 0 0 2 2 2 1 PQQ-like domain Pkinase_fungal PF17667.1 EPS29517.1 - 0.0042 15.9 0.0 0.011 14.5 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EPS29517.1 - 0.0066 15.8 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 EPS29517.1 - 0.015 14.9 0.0 0.025 14.1 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Glyco_hydro_76 PF03663.14 EPS29518.1 - 4e-139 464.2 20.1 4.6e-139 464.0 20.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Cloacin_immun PF03513.14 EPS29518.1 - 0.005 17.2 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 Cloacin immunity protein Cpn60_TCP1 PF00118.24 EPS29519.1 - 2e-144 481.9 11.8 2.3e-144 481.7 11.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 EPS29519.1 - 0.1 12.2 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat Pro_isomerase PF00160.21 EPS29520.1 - 5e-51 173.1 0.1 9.5e-51 172.2 0.1 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 EPS29520.1 - 5.8e-14 52.3 0.2 0.00016 22.3 0.0 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS29520.1 - 0.0072 16.6 0.0 1.3 9.4 0.0 3.1 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EPS29520.1 - 0.0087 15.1 0.2 0.2 10.6 0.0 2.5 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4381 PF14316.6 EPS29521.1 - 0.022 15.0 1.1 0.056 13.7 1.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Glycophorin_A PF01102.18 EPS29521.1 - 0.037 14.3 0.1 0.089 13.0 0.1 1.6 1 0 0 1 1 1 0 Glycophorin A TMEM154 PF15102.6 EPS29521.1 - 0.081 12.8 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 TMEM154 protein family DUF3619 PF12279.8 EPS29521.1 - 0.2 12.0 0.2 0.38 11.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) MFS_1 PF07690.16 EPS29523.1 - 3.8e-39 134.6 21.2 3.8e-39 134.6 21.2 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS29523.1 - 7.3e-09 35.0 2.2 7.3e-09 35.0 2.2 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EPS29523.1 - 0.0023 16.5 2.8 0.0038 15.7 2.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1129 PF06570.11 EPS29523.1 - 0.42 10.1 4.0 7.8 5.9 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) COX5A PF02284.16 EPS29524.1 - 0.17 11.9 0.0 19 5.3 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Va MGC-24 PF05283.11 EPS29524.1 - 8.6 6.8 10.6 0.62 10.5 5.6 1.6 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin MFS_1 PF07690.16 EPS29526.1 - 2.7e-33 115.4 30.3 3.4e-33 115.0 29.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_11 PF00457.17 EPS29528.1 - 3.6e-62 209.2 16.9 4.2e-62 208.9 16.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 SKG6 PF08693.10 EPS29529.1 - 1.9e-10 40.0 0.1 3.6e-10 39.1 0.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mid2 PF04478.12 EPS29529.1 - 0.011 15.6 0.1 0.032 14.1 0.1 1.7 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor DUF4448 PF14610.6 EPS29529.1 - 0.025 14.4 1.2 0.14 12.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) TrbC PF04956.13 EPS29529.1 - 0.06 13.6 0.5 0.14 12.4 0.5 1.6 1 0 0 1 1 1 0 TrbC/VIRB2 family Fungal_trans_2 PF11951.8 EPS29531.1 - 5.6e-50 170.3 0.7 8.4e-50 169.7 0.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS29531.1 - 6.8e-10 38.9 8.6 1.6e-09 37.7 8.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Opy2 PF09463.10 EPS29531.1 - 0.28 11.5 3.7 1.3 9.4 3.7 2.1 1 0 0 1 1 1 0 Opy2 protein Far-17a_AIG1 PF04750.14 EPS29532.1 - 1.6e-68 230.0 10.3 1.9e-68 229.8 10.3 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Pam17 PF08566.10 EPS29533.1 - 2.5e-67 225.9 0.0 3.3e-67 225.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 ECH_1 PF00378.20 EPS29534.1 - 2.8e-42 144.8 0.0 3.3e-42 144.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EPS29534.1 - 4.5e-24 85.5 0.0 1.3e-23 84.1 0.0 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ResIII PF04851.15 EPS29534.1 - 0.21 11.6 0.0 0.9 9.5 0.0 1.9 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit adh_short PF00106.25 EPS29537.1 - 2.8e-13 49.8 0.6 1.2e-11 44.5 0.4 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 EPS29537.1 - 1.1e-06 28.6 0.3 1.7e-06 28.1 0.3 1.2 1 0 0 1 1 1 1 KR domain BNR_2 PF13088.6 EPS29538.1 - 2.7e-09 36.7 0.1 4.5e-07 29.4 0.1 2.7 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.20 EPS29538.1 - 9.5e-06 24.9 19.4 0.28 11.3 0.5 5.7 7 0 0 7 7 7 4 BNR/Asp-box repeat DUF4185 PF13810.6 EPS29538.1 - 0.001 18.4 0.6 2.3 7.4 0.3 3.8 1 1 3 4 4 4 1 Domain of unknown function (DUF4185) BNR_4 PF15892.5 EPS29538.1 - 0.067 12.5 0.0 1.5 8.1 0.0 2.2 1 1 0 2 2 2 0 BNR repeat-containing family member Sortilin-Vps10 PF15902.5 EPS29538.1 - 0.089 11.6 0.2 3 6.5 0.1 2.6 1 1 0 2 2 2 0 Sortilin, neurotensin receptor 3, MFS_1 PF07690.16 EPS29539.1 - 6.5e-25 87.8 35.6 2.5e-24 85.9 32.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EPS29539.1 - 0.00029 19.4 4.7 0.00045 18.8 4.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) G_glu_transpept PF01019.21 EPS29540.1 - 1.3e-141 472.9 0.0 1.5e-141 472.7 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase FAA_hydrolase PF01557.18 EPS29541.1 - 2.4e-51 174.5 0.0 2.7e-51 174.3 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DHquinase_I PF01487.15 EPS29542.1 - 1.1e-29 104.3 0.0 1.8e-29 103.6 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 EPS29542.1 - 2.4e-18 66.7 0.4 5.3e-17 62.4 0.0 2.5 3 0 0 3 3 3 1 Shikimate kinase Shikimate_dh_N PF08501.11 EPS29542.1 - 6.3e-13 48.8 0.0 1.4e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.20 EPS29542.1 - 9.3e-09 35.5 0.0 2.2e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase SDH_C PF18317.1 EPS29542.1 - 4e-06 26.5 0.0 8.5e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain F420_oxidored PF03807.17 EPS29542.1 - 0.041 14.5 0.0 0.1 13.2 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent SLS PF14611.6 EPS29543.1 - 5e-36 124.6 0.1 9.5e-36 123.7 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator Ribosomal_L9_N PF01281.19 EPS29543.1 - 0.018 14.6 0.0 0.04 13.5 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L9, N-terminal domain DUF202 PF02656.15 EPS29544.1 - 1.7e-15 57.2 3.3 1.7e-15 57.2 3.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Fumarate_red_C PF02300.17 EPS29544.1 - 0.03 14.4 1.9 0.048 13.8 1.9 1.2 1 0 0 1 1 1 0 Fumarate reductase subunit C adh_short_C2 PF13561.6 EPS29545.1 - 1.4e-53 181.8 0.4 2.4e-53 181.1 0.4 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPS29545.1 - 4.6e-49 166.5 0.5 6.1e-49 166.1 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPS29545.1 - 9.8e-18 64.7 0.3 1.3e-17 64.2 0.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPS29545.1 - 0.00028 20.4 0.1 0.00051 19.6 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EPS29545.1 - 0.0039 17.1 0.2 0.0059 16.5 0.2 1.3 1 0 0 1 1 1 1 NAD(P)H-binding THF_DHG_CYH_C PF02882.19 EPS29545.1 - 0.0059 15.9 0.1 0.27 10.6 0.0 2.2 1 1 1 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GDP_Man_Dehyd PF16363.5 EPS29545.1 - 0.083 12.3 0.1 0.18 11.2 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase CoA_binding_2 PF13380.6 EPS29545.1 - 0.11 13.0 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain Scytalone_dh PF02982.14 EPS29546.1 - 5.6e-79 263.5 2.7 6.9e-79 263.2 2.7 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 EPS29546.1 - 3.5e-09 36.9 2.4 4.2e-09 36.6 2.4 1.1 1 0 0 1 1 1 1 SnoaL-like domain Abhydrolase_3 PF07859.13 EPS29547.1 - 1.5e-70 237.4 0.1 5.3e-70 235.6 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EPS29547.1 - 6.3e-11 42.2 0.0 1e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 EPS29547.1 - 2.2e-10 40.1 0.5 7.2e-10 38.3 0.5 1.6 1 1 0 1 1 1 1 Carboxylesterase family Say1_Mug180 PF10340.9 EPS29547.1 - 0.00061 18.7 0.0 0.003 16.5 0.0 2.1 3 0 0 3 3 3 1 Steryl acetyl hydrolase adh_short_C2 PF13561.6 EPS29548.1 - 5.5e-51 173.4 0.0 7.1e-51 173.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPS29548.1 - 1e-43 149.1 0.1 1.2e-43 148.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPS29548.1 - 4.1e-10 39.9 0.3 6.6e-10 39.2 0.3 1.3 1 0 0 1 1 1 1 KR domain MR_MLE_C PF13378.6 EPS29549.1 - 1.4e-41 142.5 0.0 1.9e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.16 EPS29549.1 - 1.5e-09 38.1 0.0 2.4e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DUF4149 PF13664.6 EPS29550.1 - 2.6e-22 79.1 0.8 2.6e-22 79.1 0.8 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) bZIP_1 PF00170.21 EPS29551.1 - 0.0051 16.9 6.6 0.0081 16.2 6.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor adh_short PF00106.25 EPS29552.1 - 1.3e-23 83.5 0.1 4.7e-21 75.1 0.1 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS29552.1 - 2.6e-11 43.6 0.1 1.7e-09 37.6 0.1 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPS29552.1 - 2.3e-08 34.1 0.1 1.1e-07 32.0 0.0 1.9 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 EPS29552.1 - 0.00096 18.4 0.0 0.0016 17.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 EPS29552.1 - 0.0075 16.5 0.1 0.019 15.2 0.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EPS29552.1 - 0.028 14.5 0.3 0.1 12.7 0.0 2.0 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase MatE PF01554.18 EPS29552.1 - 0.16 11.6 0.3 0.27 10.9 0.3 1.3 1 0 0 1 1 1 0 MatE Fungal_trans PF04082.18 EPS29553.1 - 1.7e-35 122.3 0.0 9.4e-35 119.9 0.0 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS29553.1 - 6.9e-08 32.5 8.7 1.2e-07 31.7 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_60s PF00428.19 EPS29553.1 - 0.00062 20.3 0.4 0.0018 18.8 0.4 1.8 1 0 0 1 1 1 1 60s Acidic ribosomal protein Hydrolase_6 PF13344.6 EPS29554.1 - 1.9e-30 104.9 0.0 3.9e-30 103.9 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EPS29554.1 - 7.7e-14 51.5 0.0 8e-13 48.3 0.0 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 EPS29554.1 - 8e-13 49.2 0.0 1.3e-05 25.6 0.0 2.9 1 1 2 3 3 3 3 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EPS29554.1 - 3.1e-05 24.1 0.1 0.13 12.4 0.0 2.5 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.14 EPS29554.1 - 0.024 14.2 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Hydrolase_3 PF08282.12 EPS29554.1 - 0.08 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Tyrosinase PF00264.20 EPS29555.1 - 7.3e-53 180.1 0.0 9.5e-53 179.7 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase OmdA PF13376.6 EPS29555.1 - 0.18 11.9 0.1 0.6 10.2 0.0 1.9 1 1 1 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated Lactonase PF10282.9 EPS29556.1 - 2.5e-86 290.1 0.1 3e-86 289.8 0.1 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller NFACT-R_1 PF05670.13 EPS29557.1 - 8.3e-40 135.8 0.0 1.3e-39 135.2 0.0 1.3 1 0 0 1 1 1 1 NFACT protein RNA binding domain TBCC PF07986.12 EPS29557.1 - 0.056 13.2 0.0 0.24 11.1 0.0 1.9 2 1 0 2 2 2 0 Tubulin binding cofactor C DUF3752 PF12572.8 EPS29558.1 - 4e-42 144.3 13.1 6.1e-42 143.7 13.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3752) Acetyltransf_1 PF00583.25 EPS29559.1 - 6.8e-14 52.1 0.0 8.5e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EPS29559.1 - 3e-10 40.4 0.0 3.8e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EPS29559.1 - 6.5e-09 35.8 0.0 8.3e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPS29559.1 - 3.8e-07 30.0 0.0 5.8e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_6 PF13480.7 EPS29559.1 - 0.00046 20.4 0.0 0.00062 19.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EPS29559.1 - 0.0035 17.4 0.0 0.0078 16.3 0.0 1.6 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase PanZ PF12568.8 EPS29559.1 - 0.013 15.2 0.1 0.02 14.6 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_9 PF13527.7 EPS29559.1 - 0.017 15.2 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain He_PIG PF05345.12 EPS29560.1 - 3.3e-17 62.4 4.2 0.0001 22.4 0.1 4.7 4 0 0 4 4 4 4 Putative Ig domain SKG6 PF08693.10 EPS29560.1 - 2.1e-06 27.1 1.1 4e-06 26.1 1.1 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DAG1 PF05454.11 EPS29560.1 - 0.011 15.1 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF4448 PF14610.6 EPS29560.1 - 0.016 15.0 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) DUF3602 PF12223.8 EPS29561.1 - 1.2e-17 64.3 8.1 4.1e-14 52.9 0.3 2.7 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) ATG16 PF08614.11 EPS29561.1 - 0.0065 16.7 1.3 0.0071 16.6 1.3 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Fungal_trans_2 PF11951.8 EPS29562.1 - 0.0081 15.0 1.7 0.0097 14.8 0.5 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF4965 PF16335.5 EPS29563.1 - 2.8e-66 222.5 0.5 4.9e-66 221.7 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4965) DUF5127 PF17168.4 EPS29563.1 - 1.5e-61 208.1 4.2 2.2e-61 207.5 4.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) DUF1793 PF08760.11 EPS29563.1 - 2.8e-40 138.5 0.2 2.8e-40 138.5 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4964 PF16334.5 EPS29563.1 - 7.8e-08 31.8 0.0 1.7e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4964) Velvet PF11754.8 EPS29566.1 - 1.6e-93 313.2 0.0 2.1e-93 312.9 0.0 1.1 1 0 0 1 1 1 1 Velvet factor Yip1 PF04893.17 EPS29567.1 - 0.013 15.3 4.6 0.014 15.2 4.6 1.1 1 0 0 1 1 1 0 Yip1 domain WD40 PF00400.32 EPS29570.1 - 1.4e-59 196.6 26.6 4.9e-11 43.0 0.1 9.1 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS29570.1 - 3.4e-20 72.1 4.2 0.00024 21.3 0.0 6.6 2 2 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EPS29570.1 - 7.1e-08 32.6 0.1 0.047 13.6 0.0 3.5 2 2 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EPS29570.1 - 6.8e-07 28.5 0.5 0.096 11.6 0.0 4.7 3 2 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EPS29570.1 - 2.8e-06 26.3 3.7 0.14 10.8 0.1 5.2 4 2 1 6 6 6 2 Nucleoporin Nup120/160 NLE PF08154.12 EPS29570.1 - 0.00023 21.6 0.0 0.00048 20.6 0.0 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain FAD_binding_9 PF08021.11 EPS29570.1 - 0.0092 16.2 0.1 0.41 10.9 0.0 2.6 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain WD40_like PF17005.5 EPS29570.1 - 0.029 13.7 0.0 25 4.1 0.0 3.7 4 1 1 5 5 5 0 WD40-like domain 120_Rick_ant PF12574.8 EPS29570.1 - 0.055 12.6 0.2 0.55 9.4 0.0 2.1 2 0 0 2 2 2 0 120 KDa Rickettsia surface antigen DUF4550 PF15084.6 EPS29570.1 - 0.11 12.9 0.0 0.74 10.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4550) TFIIIC_delta PF12657.7 EPS29570.1 - 0.15 12.0 1.2 2.7 7.9 0.1 3.0 3 1 0 3 3 3 0 Transcription factor IIIC subunit delta N-term SWIB PF02201.18 EPS29571.1 - 2.3e-29 101.1 0.1 5.4e-29 99.9 0.1 1.7 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.11 EPS29571.1 - 3.2e-15 55.8 0.4 6.6e-15 54.8 0.4 1.6 1 0 0 1 1 1 1 DEK C terminal domain Ndc1_Nup PF09531.10 EPS29571.1 - 0.86 8.2 6.0 1 8.0 6.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-C3HC4_3 PF13920.6 EPS29572.1 - 1.8e-07 30.9 8.2 1.8e-07 30.9 8.2 3.4 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EPS29572.1 - 0.011 15.6 10.3 0.011 15.6 10.3 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) MutS_V PF00488.21 EPS29573.1 - 4.8e-60 202.8 0.1 9.4e-60 201.9 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EPS29573.1 - 3.5e-33 115.4 2.8 6.2e-33 114.6 0.9 2.3 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 EPS29573.1 - 3.6e-12 46.5 0.0 7.4e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 EPS29573.1 - 7.2e-07 29.6 0.1 2.4e-06 27.9 0.1 1.9 1 1 0 1 1 1 1 MutS domain II AAA_30 PF13604.6 EPS29573.1 - 0.047 13.4 0.1 0.16 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 EPS29573.1 - 0.11 12.1 0.2 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain eIF2A PF08662.11 EPS29574.1 - 2.4e-37 128.7 6.8 1e-34 120.2 3.6 4.0 3 2 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 EPS29574.1 - 5.6e-07 29.3 0.0 1.3e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 EPS29574.1 - 0.016 16.1 0.6 4.4 8.3 0.0 4.2 4 0 0 4 4 4 0 WD domain, G-beta repeat Lyase_1 PF00206.20 EPS29574.1 - 0.12 11.7 0.1 0.21 11.0 0.1 1.3 1 0 0 1 1 1 0 Lyase CAP PF00188.26 EPS29575.1 - 2e-21 77.1 1.8 5.3e-21 75.8 1.8 1.8 1 1 0 1 1 1 1 Cysteine-rich secretory protein family Sec10 PF07393.11 EPS29576.1 - 4.5e-177 590.6 0.0 5.1e-177 590.5 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.7 EPS29576.1 - 3.1e-06 27.0 0.1 8.7e-06 25.5 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EPS29576.1 - 0.0002 21.2 0.0 0.00046 20.0 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EPS29576.1 - 0.033 14.1 0.0 0.079 12.8 0.0 1.5 1 0 0 1 1 1 0 F-box CDO_I PF05995.12 EPS29577.1 - 4.7e-39 133.4 0.1 5.9e-39 133.1 0.1 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I PCO_ADO PF07847.12 EPS29577.1 - 0.0009 18.7 0.3 0.0013 18.2 0.3 1.4 1 1 0 1 1 1 1 PCO_ADO Auxin_BP PF02041.16 EPS29577.1 - 0.013 15.2 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Auxin binding protein Fungal_trans PF04082.18 EPS29578.1 - 1.6e-09 37.2 0.1 2.9e-09 36.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MinC_N PF05209.13 EPS29578.1 - 0.17 11.9 0.0 0.61 10.1 0.0 1.8 2 0 0 2 2 2 0 Septum formation inhibitor MinC, N-terminal domain SLAC1 PF03595.17 EPS29579.1 - 6.3e-94 314.9 57.3 7.1e-94 314.7 57.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF5056 PF16479.5 EPS29579.1 - 0.034 14.4 3.7 0.18 12.1 0.5 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5056) Cytochrom_C1 PF02167.15 EPS29580.1 - 1.2e-90 303.0 0.0 1.6e-90 302.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 EPS29580.1 - 0.007 16.7 0.0 0.016 15.5 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 EPS29580.1 - 0.13 13.4 0.2 0.94 10.7 0.2 2.5 2 1 0 2 2 2 0 Cytochrome c AIG2_2 PF13772.6 EPS29581.1 - 5.9e-05 23.4 0.0 0.00027 21.3 0.0 2.0 2 0 0 2 2 2 1 AIG2-like family IMUP PF15761.5 EPS29582.1 - 0.00096 19.8 2.0 0.00096 19.8 2.0 3.2 3 0 0 3 3 3 1 Immortalisation up-regulated protein SIKE PF05769.11 EPS29582.1 - 0.13 12.1 6.6 0.32 10.9 6.6 1.5 1 0 0 1 1 1 0 SIKE family DUF2570 PF10828.8 EPS29582.1 - 0.54 10.1 7.0 0.75 9.6 5.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) DAHP_synth_1 PF00793.20 EPS29583.1 - 3.3e-104 347.6 0.0 4.2e-104 347.3 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family F-box-like PF12937.7 EPS29584.1 - 0.00059 19.7 0.4 0.0015 18.4 0.1 1.8 2 0 0 2 2 2 1 F-box-like hDGE_amylase PF14701.6 EPS29585.1 - 1.3e-181 604.6 0.0 1.6e-181 604.2 0.0 1.1 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 EPS29585.1 - 1e-118 396.6 0.0 3e-118 395.1 0.0 1.7 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 EPS29585.1 - 3.6e-86 288.9 0.0 6.5e-86 288.1 0.0 1.4 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 EPS29585.1 - 8.3e-30 102.8 0.0 1.9e-29 101.6 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 EPS29585.1 - 0.02 14.5 0.3 0.052 13.1 0.0 1.7 2 0 0 2 2 2 0 Alpha amylase, catalytic domain DUF2868 PF11067.8 EPS29586.1 - 0.096 12.2 0.2 0.11 11.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) NAD_Gly3P_dh_N PF01210.23 EPS29587.1 - 2.8e-47 160.6 0.1 6.2e-47 159.5 0.0 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 EPS29587.1 - 7.4e-45 152.7 0.1 1.2e-44 152.1 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 EPS29587.1 - 0.049 14.2 0.0 3.3 8.4 0.0 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent SLX9 PF15341.6 EPS29588.1 - 3.6e-33 114.8 10.2 4.2e-33 114.5 10.2 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 HrpJ PF07201.11 EPS29588.1 - 0.015 15.6 1.0 0.022 15.1 1.0 1.2 1 0 0 1 1 1 0 HrpJ-like domain NAD_binding_10 PF13460.6 EPS29589.1 - 8.6e-05 22.5 0.0 0.00012 22.1 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EPS29589.1 - 0.003 17.1 0.0 0.0038 16.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family FAD_binding_4 PF01565.23 EPS29590.1 - 4.9e-21 74.9 0.8 1.3e-20 73.6 0.8 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EPS29590.1 - 1.7e-10 40.8 0.1 3.2e-10 40.0 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like AAA_2 PF07724.14 EPS29591.1 - 6.1e-37 127.3 0.0 5.6e-36 124.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 EPS29591.1 - 1.2e-14 54.8 0.0 2.4e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EPS29591.1 - 3.2e-09 36.7 0.2 1.2e-08 34.8 0.0 2.0 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 EPS29591.1 - 4e-06 26.9 0.0 1.3e-05 25.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EPS29591.1 - 0.0002 21.6 0.3 0.0033 17.7 0.3 2.3 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EPS29591.1 - 0.00021 20.7 0.3 0.013 14.9 0.0 3.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EPS29591.1 - 0.00041 20.1 0.0 0.094 12.4 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.6 EPS29591.1 - 0.0025 18.2 0.4 0.014 15.8 0.2 2.2 1 1 1 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 EPS29591.1 - 0.0053 16.5 0.0 0.0095 15.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EPS29591.1 - 0.0063 16.3 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 EPS29591.1 - 0.0075 16.0 0.1 0.079 12.7 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain MCM PF00493.23 EPS29591.1 - 0.04 13.0 0.1 0.1 11.7 0.1 1.6 2 0 0 2 2 2 0 MCM P-loop domain RNA_helicase PF00910.22 EPS29591.1 - 0.046 14.1 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 EPS29591.1 - 0.073 13.6 0.0 0.16 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EPS29591.1 - 0.077 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 EPS29591.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EPS29591.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EPS29591.1 - 0.12 12.2 0.3 1.3 8.9 0.3 2.3 1 1 0 1 1 1 0 NACHT domain AAA_3 PF07726.11 EPS29591.1 - 0.13 12.1 0.0 0.34 10.8 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.6 EPS29591.1 - 0.13 12.3 0.0 0.61 10.2 0.0 2.1 2 1 0 2 2 2 0 Sigma-54 interaction domain Rad17 PF03215.15 EPS29591.1 - 0.17 11.8 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain Chromo PF00385.24 EPS29592.1 - 1.6e-09 37.6 0.3 3.2e-09 36.6 0.3 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 EPS29592.1 - 0.0042 17.2 0.2 0.012 15.8 0.2 1.7 1 0 0 1 1 1 1 Polycomb-like MTF2 factor 2 AMP-binding PF00501.28 EPS29593.1 - 1.6e-214 712.3 0.0 6e-76 255.7 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.20 EPS29593.1 - 2.5e-117 392.4 0.0 5.2e-31 107.8 0.0 9.6 8 2 0 8 8 8 8 Condensation domain PP-binding PF00550.25 EPS29593.1 - 4.8e-36 122.9 5.2 3.1e-12 46.6 0.1 3.9 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EPS29593.1 - 2.2e-13 51.0 0.0 0.0019 19.2 0.0 3.8 3 0 0 3 3 3 3 AMP-binding enzyme C-terminal domain GH3 PF03321.13 EPS29593.1 - 0.0016 17.4 0.8 0.071 12.0 0.0 3.5 4 0 0 4 4 4 1 GH3 auxin-responsive promoter DUF547 PF04784.14 EPS29593.1 - 0.062 13.3 0.2 5.5 7.1 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function, DUF547 MFS_1 PF07690.16 EPS29594.1 - 5.7e-41 140.6 49.9 9.8e-39 133.3 33.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS29594.1 - 1.6e-13 50.3 9.6 1.6e-13 50.3 9.6 2.6 2 1 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 EPS29594.1 - 9.1e-07 27.7 11.9 1.4e-06 27.0 8.6 2.4 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Na_Ala_symp PF01235.17 EPS29594.1 - 0.00051 19.5 4.3 0.00051 19.5 4.3 1.6 2 0 0 2 2 2 1 Sodium:alanine symporter family UL42 PF17638.2 EPS29594.1 - 0.0084 16.1 0.2 0.24 11.4 0.1 2.6 2 0 0 2 2 2 1 HCMV UL42 MFS_3 PF05977.13 EPS29594.1 - 0.011 14.1 4.9 0.01 14.3 3.5 1.6 1 1 0 1 1 1 0 Transmembrane secretion effector MFS_1 PF07690.16 EPS29595.1 - 2.4e-16 59.6 48.5 3.5e-16 59.1 35.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ras PF00071.22 EPS29596.1 - 1.3e-63 213.4 0.2 1.5e-63 213.2 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EPS29596.1 - 1.2e-35 122.3 0.2 1.7e-35 121.9 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPS29596.1 - 2.9e-13 49.6 0.1 3.7e-13 49.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EPS29596.1 - 5.5e-08 32.9 0.1 8.3e-08 32.3 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EPS29596.1 - 8e-05 22.6 0.2 0.015 15.2 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 EPS29596.1 - 0.00044 19.7 0.1 0.00068 19.1 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EPS29596.1 - 0.00045 19.8 0.1 0.0018 17.9 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 EPS29596.1 - 0.0029 17.9 0.0 0.02 15.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EPS29596.1 - 0.012 16.0 0.1 0.019 15.3 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 EPS29596.1 - 0.013 15.6 0.2 0.04 14.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.10 EPS29596.1 - 0.017 14.6 0.0 0.029 13.8 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 EPS29596.1 - 0.022 15.3 0.1 0.033 14.7 0.1 1.4 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.6 EPS29596.1 - 0.027 14.2 0.1 0.06 13.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 EPS29596.1 - 0.059 12.8 0.0 0.17 11.3 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein AAA_21 PF13304.6 EPS29596.1 - 0.095 12.5 0.8 0.14 12.0 0.6 1.5 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system FeoB_N PF02421.18 EPS29596.1 - 0.098 12.2 0.1 0.23 11.0 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B MCM PF00493.23 EPS29596.1 - 0.11 11.6 0.0 0.23 10.6 0.0 1.5 1 1 0 1 1 1 0 MCM P-loop domain AAA_7 PF12775.7 EPS29596.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AEP1 PF17049.5 EPS29596.1 - 0.12 11.4 0.1 0.16 11.0 0.1 1.1 1 0 0 1 1 1 0 ATPase expression protein 1 Brix PF04427.18 EPS29597.1 - 7.8e-31 107.7 0.0 1.1e-30 107.3 0.0 1.2 1 0 0 1 1 1 1 Brix domain DUF688 PF05097.12 EPS29597.1 - 0.14 11.3 1.1 0.2 10.8 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF688) PfkB PF00294.24 EPS29598.1 - 5e-16 58.9 0.0 1.2e-15 57.6 0.0 1.6 1 1 0 1 1 1 1 pfkB family carbohydrate kinase DUF4820 PF16091.5 EPS29600.1 - 0.071 12.5 1.6 0.084 12.2 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Bro-N PF02498.17 EPS29600.1 - 0.14 12.9 0.1 0.22 12.2 0.1 1.5 1 0 0 1 1 1 0 BRO family, N-terminal domain Abp2 PF09441.10 EPS29602.1 - 5.7e-88 293.4 0.0 9.8e-88 292.6 0.0 1.4 1 0 0 1 1 1 1 ARS binding protein 2 DUF3022 PF11226.8 EPS29602.1 - 0.071 13.6 0.0 0.2 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3022) ARID PF01388.21 EPS29602.1 - 0.087 13.5 0.1 0.21 12.3 0.1 1.6 1 0 0 1 1 1 0 ARID/BRIGHT DNA binding domain Med9 PF07544.13 EPS29602.1 - 0.13 12.4 0.4 0.38 10.9 0.4 1.8 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 BESS PF02944.20 EPS29603.1 - 0.049 13.5 1.5 0.95 9.3 0.0 3.2 3 0 0 3 3 3 0 BESS motif F-box-like PF12937.7 EPS29603.1 - 0.094 12.6 0.9 0.23 11.4 0.9 1.7 1 0 0 1 1 1 0 F-box-like LRR_4 PF12799.7 EPS29603.1 - 0.17 12.4 3.8 3.4 8.2 0.3 3.8 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) WW PF00397.26 EPS29604.1 - 2.3e-05 24.4 2.4 7.4e-05 22.7 2.4 2.0 1 0 0 1 1 1 1 WW domain Quaking_NLS PF16551.5 EPS29604.1 - 0.017 14.8 0.1 0.23 11.1 0.0 2.4 2 0 0 2 2 2 0 Putative nuclear localisation signal of quaking Pox_A12 PF04651.13 EPS29607.1 - 0.034 14.2 0.9 0.044 13.8 0.9 1.1 1 0 0 1 1 1 0 Poxvirus A12 protein MAP65_ASE1 PF03999.12 EPS29607.1 - 0.13 10.9 3.1 0.15 10.7 3.1 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) ORC6 PF05460.13 EPS29607.1 - 0.25 10.6 5.2 0.28 10.4 5.2 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Fungal_trans PF04082.18 EPS29609.1 - 5.3e-08 32.2 0.1 1.6e-07 30.7 0.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EPS29609.1 - 9.6e-06 25.8 15.3 0.00085 19.7 0.7 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPS29609.1 - 0.00013 22.5 14.8 0.0047 17.6 0.8 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EPS29609.1 - 0.00021 21.5 14.3 0.00047 20.4 5.0 3.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EPS29609.1 - 0.0095 16.2 3.4 3.6 8.0 0.8 3.4 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EPS29609.1 - 0.61 10.6 4.1 1.3 9.5 0.5 3.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-Paramyx-P PF13008.7 EPS29609.1 - 1.7 8.2 4.4 4.3 6.9 4.4 1.7 1 0 0 1 1 1 0 Zinc-binding domain of Paramyxoviridae V protein FAA_hydrolase PF01557.18 EPS29610.1 - 5.7e-53 179.8 0.0 7.5e-53 179.4 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family B12-binding PF02310.19 EPS29611.1 - 0.001 19.1 0.1 0.0015 18.6 0.1 1.2 1 0 0 1 1 1 1 B12 binding domain Lant_dehydr_N PF04738.13 EPS29611.1 - 0.072 11.2 0.0 0.08 11.0 0.0 1.0 1 0 0 1 1 1 0 Lantibiotic dehydratase, N terminus ETX_MTX2 PF03318.13 EPS29613.1 - 7.3e-12 45.5 7.4 1e-11 45.1 7.4 1.2 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Aerolysin PF01117.20 EPS29613.1 - 1.5e-06 27.7 1.2 1.9e-06 27.4 1.2 1.1 1 0 0 1 1 1 1 Aerolysin toxin Urocanase_C PF17392.2 EPS29613.1 - 0.017 14.6 0.1 0.022 14.2 0.1 1.2 1 0 0 1 1 1 0 Urocanase C-terminal domain NmrA PF05368.13 EPS29614.1 - 6.3e-12 45.6 0.0 1.4e-11 44.4 0.0 1.5 1 1 1 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 EPS29614.1 - 1.3e-10 41.5 0.1 1.8e-10 41.0 0.1 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 EPS29614.1 - 0.0091 16.4 0.1 0.014 15.8 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 EPS29614.1 - 0.042 14.0 0.2 0.22 11.6 0.2 2.1 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.22 EPS29614.1 - 0.044 14.6 0.0 0.082 13.7 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Epimerase PF01370.21 EPS29614.1 - 0.093 12.2 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family KR PF08659.10 EPS29614.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 KR domain EHN PF06441.12 EPS29616.1 - 5.8e-34 116.7 2.6 2.2e-33 114.8 0.2 2.2 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_1 PF00561.20 EPS29616.1 - 2.9e-07 30.4 0.2 5.6e-07 29.5 0.2 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 EPS29617.1 - 6.4e-23 81.7 0.0 1e-21 77.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPS29617.1 - 5.4e-14 53.3 0.0 7.3e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPS29617.1 - 2.2e-10 40.2 0.0 3.4e-10 39.6 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EPS29617.1 - 6e-09 36.0 0.2 8.5e-07 28.9 0.2 2.1 1 1 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 EPS29617.1 - 4.9e-08 33.4 0.0 7.9e-08 32.7 0.0 1.4 1 1 0 1 1 1 1 Thioesterase domain Ndr PF03096.14 EPS29617.1 - 0.0012 17.6 0.0 0.002 16.9 0.0 1.4 1 1 0 1 1 1 1 Ndr family Esterase PF00756.20 EPS29617.1 - 0.0071 16.0 0.0 0.017 14.8 0.0 1.7 2 0 0 2 2 2 1 Putative esterase Ser_hydrolase PF06821.13 EPS29617.1 - 0.011 15.6 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_5 PF12695.7 EPS29617.1 - 0.012 15.4 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 EPS29617.1 - 0.018 14.9 0.0 0.025 14.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF676 PF05057.14 EPS29617.1 - 0.022 14.3 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Lipase_3 PF01764.25 EPS29617.1 - 0.027 14.3 0.0 0.053 13.4 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF915 PF06028.11 EPS29617.1 - 0.049 13.0 0.0 4.7 6.5 0.0 3.0 4 0 0 4 4 4 0 Alpha/beta hydrolase of unknown function (DUF915) Palm_thioest PF02089.15 EPS29617.1 - 0.059 13.2 0.0 0.087 12.6 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_2 PF02230.16 EPS29617.1 - 0.064 13.1 0.0 0.52 10.1 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Chlorophyllase2 PF12740.7 EPS29617.1 - 0.11 11.4 0.0 0.29 10.0 0.0 1.7 2 0 0 2 2 2 0 Chlorophyllase enzyme LIDHydrolase PF10230.9 EPS29617.1 - 0.16 11.5 0.0 0.33 10.5 0.0 1.6 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase LCAT PF02450.15 EPS29617.1 - 0.16 11.1 0.1 0.25 10.5 0.1 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase NPV_P10 PF05531.12 EPS29618.1 - 0.00017 22.0 16.7 1 9.9 0.1 6.9 5 1 2 7 7 7 2 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 EPS29618.1 - 0.017 15.1 22.8 2 8.5 0.7 6.1 4 3 2 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 EPS29618.1 - 0.025 14.8 13.9 8.3 6.7 3.7 6.0 4 2 0 4 4 4 0 Bacterial protein of unknown function (DUF948) CHASE6_C PF17150.4 EPS29618.1 - 0.034 14.8 0.3 0.29 11.8 0.1 2.8 2 0 0 2 2 2 0 C-terminal domain of two-partite extracellular sensor domain DUF16 PF01519.16 EPS29618.1 - 0.071 13.6 0.2 0.071 13.6 0.2 6.7 4 2 1 5 5 5 0 Protein of unknown function DUF16 FtsQ PF03799.15 EPS29618.1 - 0.58 11.0 5.7 5.5 7.8 0.1 3.9 3 2 0 3 3 3 0 Cell division protein FtsQ DASH_Dam1 PF08653.10 EPS29618.1 - 3.8 7.4 7.4 33 4.4 0.0 5.3 5 0 0 5 5 5 0 DASH complex subunit Dam1 RPW8 PF05659.11 EPS29618.1 - 4.1 7.1 12.4 0.93 9.2 0.2 4.2 4 1 1 5 5 5 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 FlaC_arch PF05377.11 EPS29618.1 - 4.4 7.8 21.4 4.5 7.7 0.5 7.4 8 1 1 9 9 9 0 Flagella accessory protein C (FlaC) Plasmid_RAQPRD PF09686.10 EPS29618.1 - 4.8 7.5 9.7 2.5 8.4 0.0 4.4 4 0 0 4 4 4 0 Plasmid protein of unknown function (Plasmid_RAQPRD) TIP49 PF06068.13 EPS29619.1 - 1.8e-154 514.2 3.2 2.8e-154 513.6 3.2 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EPS29619.1 - 7.6e-21 74.0 0.4 2.7e-20 72.3 0.4 2.0 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 EPS29619.1 - 1.5e-08 35.1 2.0 1.7e-05 25.3 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EPS29619.1 - 4.7e-08 32.9 0.4 4.3e-05 23.3 0.1 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 EPS29619.1 - 1.7e-06 27.6 1.3 3.4e-06 26.6 1.3 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 EPS29619.1 - 4e-06 27.3 0.5 1.2e-05 25.8 0.1 2.1 2 1 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 EPS29619.1 - 0.0024 17.3 1.0 0.033 13.6 0.6 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EPS29619.1 - 0.0039 17.2 0.2 0.5 10.4 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EPS29619.1 - 0.0053 17.0 0.0 0.54 10.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 EPS29619.1 - 0.006 16.3 0.1 3.1 7.5 0.1 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.6 EPS29619.1 - 0.013 15.1 0.1 0.026 14.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EPS29619.1 - 0.014 15.7 1.8 0.23 11.8 1.9 2.6 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EPS29619.1 - 0.033 14.0 0.8 0.13 12.0 0.8 2.1 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EPS29619.1 - 0.058 13.5 0.0 0.16 12.2 0.0 1.7 2 0 0 2 2 1 0 AAA domain Parvo_NS1 PF01057.17 EPS29619.1 - 0.075 12.1 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 EPS29619.1 - 0.077 12.5 0.3 0.31 10.5 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_28 PF13521.6 EPS29619.1 - 0.12 12.6 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain GYF PF02213.16 EPS29620.1 - 9.7e-13 47.6 1.2 2.5e-12 46.3 1.2 1.7 1 0 0 1 1 1 1 GYF domain C12orf66_like PF09404.10 EPS29620.1 - 0.02 13.8 0.0 0.027 13.3 0.0 1.1 1 0 0 1 1 1 0 KICSTOR complex C12orf66 like UFD1 PF03152.14 EPS29621.1 - 6.7e-75 250.3 0.0 8.5e-75 250.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.17 EPS29621.1 - 0.014 15.2 0.0 0.2 11.5 0.0 2.3 1 1 1 2 2 2 0 Cell division protein 48 (CDC48), domain 2 DUF829 PF05705.14 EPS29622.1 - 2.9e-57 194.3 0.1 3.4e-57 194.1 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DUF4246 PF14033.6 EPS29623.1 - 9.2e-128 427.2 0.0 1.2e-127 426.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) RNA_pol_Rpb2_6 PF00562.28 EPS29624.1 - 1.4e-124 416.1 0.4 4.1e-124 414.6 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EPS29624.1 - 8.8e-55 185.4 0.2 1.4e-54 184.7 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 EPS29624.1 - 7.8e-33 112.7 0.3 2e-32 111.5 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 EPS29624.1 - 8.3e-29 100.6 1.9 1.7e-28 99.6 1.9 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 EPS29624.1 - 8.2e-24 83.7 0.4 2.1e-23 82.4 0.4 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 EPS29624.1 - 1.7e-19 69.8 0.0 4.2e-19 68.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 EPS29624.1 - 8.3e-11 42.3 1.0 2.6e-10 40.7 1.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 NRDD PF13597.6 EPS29624.1 - 0.08 11.7 0.2 0.13 11.0 0.2 1.2 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase PUF PF00806.19 EPS29625.1 - 1e-58 191.8 6.5 9.5e-07 28.2 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 EPS29625.1 - 0.00057 20.3 0.5 0.31 11.4 0.0 4.0 1 1 1 4 4 4 1 CPL (NUC119) domain ORC5_C PF14630.6 EPS29626.1 - 5.9e-86 288.5 0.0 7.5e-86 288.2 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 EPS29626.1 - 1.4e-16 61.4 0.1 3.4e-16 60.1 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EPS29626.1 - 0.0076 16.7 0.0 0.015 15.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ORC2 PF04084.14 EPS29626.1 - 0.042 12.8 0.0 0.069 12.0 0.0 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 2 AAA_33 PF13671.6 EPS29626.1 - 0.069 13.3 0.2 0.22 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 EPS29626.1 - 0.19 10.9 0.0 0.32 10.2 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain EF-hand_4 PF12763.7 EPS29628.1 - 4.8e-36 122.9 0.0 2.2e-13 50.1 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 EPS29628.1 - 8.7e-09 35.7 0.0 0.0015 18.9 0.0 4.5 4 0 0 4 4 4 1 EF-hand domain pair UBA PF00627.31 EPS29628.1 - 7e-08 32.2 0.0 1.3e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_1 PF00036.32 EPS29628.1 - 8.6e-08 31.2 0.0 0.0029 17.0 0.0 4.8 5 0 0 5 5 5 1 EF hand EF-hand_6 PF13405.6 EPS29628.1 - 2.2e-05 24.0 0.5 3.5 7.8 0.0 5.4 5 0 0 5 5 5 1 EF-hand domain GAS PF13851.6 EPS29628.1 - 0.00015 21.2 23.3 0.0081 15.5 9.3 2.2 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding EF-hand_8 PF13833.6 EPS29628.1 - 0.00053 19.8 0.0 0.4 10.6 0.0 3.9 4 0 0 4 4 4 1 EF-hand domain pair DUF3450 PF11932.8 EPS29628.1 - 0.0051 16.2 12.5 0.0051 16.2 12.5 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF3450) Spc7 PF08317.11 EPS29628.1 - 0.0083 15.0 27.2 0.091 11.6 13.1 2.1 1 1 1 2 2 2 2 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 EPS29628.1 - 0.018 14.6 7.0 0.029 14.0 7.0 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit TPR_MLP1_2 PF07926.12 EPS29628.1 - 0.028 14.5 29.9 0.12 12.5 16.9 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein TMF_TATA_bd PF12325.8 EPS29628.1 - 0.15 12.3 23.7 0.11 12.7 3.8 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Myosin_tail_1 PF01576.19 EPS29628.1 - 0.26 9.0 23.9 0.39 8.4 23.9 1.2 1 0 0 1 1 1 0 Myosin tail ATG16 PF08614.11 EPS29628.1 - 0.27 11.4 31.2 0.27 11.5 14.1 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF3584 PF12128.8 EPS29628.1 - 0.4 8.1 22.4 0.55 7.7 22.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FUSC PF04632.12 EPS29628.1 - 0.93 7.9 10.7 1.4 7.3 10.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family zf-C4H2 PF10146.9 EPS29628.1 - 1.2 9.4 20.8 2.3e+02 2.0 20.8 3.1 1 1 0 1 1 1 0 Zinc finger-containing protein COG2 PF06148.11 EPS29628.1 - 1.9 8.6 10.1 2.4 8.2 0.9 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Macoilin PF09726.9 EPS29628.1 - 2.1 6.8 13.2 0.064 11.8 7.2 1.5 2 0 0 2 2 2 0 Macoilin family AAA_13 PF13166.6 EPS29628.1 - 3.4 6.2 16.2 6.3 5.3 16.2 1.4 1 0 0 1 1 1 0 AAA domain LPP PF04728.13 EPS29628.1 - 3.7 8.0 10.1 9.5 6.7 1.2 2.9 2 1 0 2 2 2 0 Lipoprotein leucine-zipper CENP-F_leu_zip PF10473.9 EPS29628.1 - 7.8 6.5 23.0 0.33 11.0 5.4 2.5 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tubulin PF00091.25 EPS29629.1 - 4e-67 226.2 0.0 8.6e-67 225.2 0.0 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EPS29629.1 - 1.1e-49 167.7 0.0 2.6e-49 166.6 0.0 1.6 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EPS29629.1 - 0.0023 17.7 0.0 0.0048 16.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Pga1 PF10333.9 EPS29630.1 - 0.00072 19.5 0.3 0.002 18.0 0.0 1.8 2 0 0 2 2 2 1 GPI-Mannosyltransferase II co-activator Abdominal-A PF12407.8 EPS29630.1 - 0.44 10.2 3.9 0.68 9.6 3.9 1.3 1 0 0 1 1 1 0 Homeobox protein tRNA-synt_2 PF00152.20 EPS29631.1 - 2.9e-72 243.4 0.0 4.6e-72 242.8 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.9 EPS29631.1 - 1.8e-17 63.3 0.0 2.5e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) tRNA_anti-codon PF01336.25 EPS29631.1 - 0.0018 18.2 0.0 0.0035 17.3 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EPS29631.1 - 0.0058 16.1 0.1 1 8.8 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) MCM_N PF14551.6 EPS29631.1 - 0.093 13.3 0.0 0.3 11.7 0.0 1.9 1 0 0 1 1 1 0 MCM N-terminal domain Abhydrolase_3 PF07859.13 EPS29633.1 - 6.4e-44 150.3 0.1 1.1e-43 149.5 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EPS29633.1 - 0.00024 20.1 0.3 0.00084 18.3 0.3 1.7 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 EPS29633.1 - 0.017 14.6 0.3 1.5 8.2 0.1 2.4 2 1 0 2 2 2 0 Prolyl oligopeptidase family DUF2974 PF11187.8 EPS29633.1 - 0.07 12.7 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) RRN3 PF05327.11 EPS29634.1 - 1.4e-171 571.9 0.0 1.4e-171 571.9 0.0 1.9 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 Hamartin PF04388.12 EPS29635.1 - 1.2 7.7 9.2 1.3 7.5 9.2 1.1 1 0 0 1 1 1 0 Hamartin protein Fungal_trans PF04082.18 EPS29636.1 - 4.4e-21 75.1 0.3 2.1e-20 72.9 0.2 2.2 2 1 0 2 2 2 1 Fungal specific transcription factor domain Iso_dh PF00180.20 EPS29637.1 - 2.1e-85 286.9 0.0 2.4e-85 286.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Gp_dh_C PF02800.20 EPS29638.1 - 3.5e-57 192.4 0.0 5e-57 191.9 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EPS29638.1 - 1e-32 112.4 0.0 2.2e-32 111.4 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 EPS29638.1 - 0.0048 16.3 0.0 0.0093 15.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DapB_N PF01113.20 EPS29638.1 - 0.03 14.5 0.3 0.1 12.7 0.0 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus WD40 PF00400.32 EPS29639.1 - 1e-16 61.0 8.1 0.0058 17.5 0.7 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS29639.1 - 4.5e-07 30.1 0.1 0.062 13.6 0.1 5.1 4 1 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EPS29639.1 - 9.7e-07 27.8 1.6 5.2e-05 22.1 0.3 2.4 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EPS29639.1 - 0.012 14.4 0.0 2.3 6.8 0.0 2.7 2 1 1 3 3 3 0 Nup133 N terminal like Cmc1 PF08583.10 EPS29640.1 - 5.5e-18 64.8 3.4 7e-18 64.4 3.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Fcf1 PF04900.12 EPS29641.1 - 1.7e-19 70.0 0.3 5.7e-11 42.7 0.0 2.3 2 0 0 2 2 2 2 Fcf1 DUF4551 PF15087.6 EPS29641.1 - 0.38 9.5 7.2 0.49 9.2 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) SpoIIE PF07228.12 EPS29642.1 - 0.00013 21.9 0.0 0.00068 19.6 0.0 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 EPS29642.1 - 0.00058 19.6 0.1 0.83 9.2 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C P34-Arc PF04045.14 EPS29644.1 - 1.1e-108 362.5 0.2 1.3e-108 362.2 0.2 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc WD40 PF00400.32 EPS29645.1 - 6.2e-52 172.4 23.7 2e-07 31.6 0.2 11.9 12 0 0 12 12 12 9 WD domain, G-beta repeat Utp12 PF04003.12 EPS29645.1 - 3.6e-20 72.3 0.4 7.5e-20 71.2 0.4 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 EPS29645.1 - 1.7e-19 69.9 4.9 0.034 14.4 0.0 9.2 7 3 3 10 10 10 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EPS29645.1 - 6.4e-06 25.3 2.7 4.3 6.2 0.0 5.7 3 2 2 6 6 6 4 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EPS29645.1 - 1.7e-05 23.7 3.5 0.82 8.2 0.0 5.5 4 2 1 6 6 6 2 Nucleoporin Nup120/160 RAB3GAP2_N PF14655.6 EPS29645.1 - 0.0004 19.8 0.3 1.3 8.2 0.0 3.7 4 0 0 4 4 4 2 Rab3 GTPase-activating protein regulatory subunit N-terminus Frtz PF11768.8 EPS29645.1 - 0.00062 18.2 0.0 0.019 13.3 0.0 2.6 2 1 0 2 2 2 1 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 EPS29645.1 - 0.0011 18.4 0.0 0.87 8.9 0.0 3.6 4 0 0 4 4 4 1 WD40-like domain PALB2_WD40 PF16756.5 EPS29645.1 - 0.0034 16.4 2.2 2 7.2 0.0 3.5 4 0 0 4 4 4 2 Partner and localizer of BRCA2 WD40 domain PQQ_2 PF13360.6 EPS29645.1 - 0.0095 15.5 0.9 3.3 7.2 0.1 2.9 2 1 0 2 2 2 2 PQQ-like domain Nucleoporin_N PF08801.11 EPS29645.1 - 0.01 14.6 0.4 0.3 9.8 0.0 3.4 3 1 1 4 4 4 0 Nup133 N terminal like WLM PF08325.10 EPS29646.1 - 3.7e-66 222.9 0.2 5.9e-66 222.2 0.2 1.3 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.18 EPS29646.1 - 8.7e-05 21.8 5.3 8.7e-05 21.8 5.3 3.3 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others DZR PF12773.7 EPS29646.1 - 0.0022 18.0 9.3 0.24 11.4 0.5 2.4 2 0 0 2 2 2 2 Double zinc ribbon DUF45 PF01863.17 EPS29646.1 - 0.014 15.5 2.9 0.014 15.5 2.9 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF45 C1_1 PF00130.22 EPS29646.1 - 0.016 15.1 2.9 0.016 15.1 2.9 2.6 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SprT-like PF10263.9 EPS29646.1 - 0.046 13.6 0.1 0.095 12.6 0.1 1.5 1 0 0 1 1 1 0 SprT-like family zf-ribbon_3 PF13248.6 EPS29646.1 - 0.53 9.8 8.8 0.069 12.6 1.8 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DUF1776 PF08643.10 EPS29647.1 - 2.6e-101 338.9 0.0 3.2e-101 338.6 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short PF00106.25 EPS29647.1 - 0.0013 18.2 0.0 0.011 15.1 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase Sel1 PF08238.12 EPS29650.1 - 1.7e-10 41.2 7.0 0.025 15.3 0.9 3.8 4 0 0 4 4 4 3 Sel1 repeat DNA_binding_2 PF13724.6 EPS29650.1 - 0.029 14.8 1.4 0.18 12.3 1.4 2.5 1 0 0 1 1 1 0 DNA-binding domain Phage_Gp17 PF17549.2 EPS29650.1 - 0.047 13.7 0.3 0.086 12.9 0.3 1.4 1 0 0 1 1 1 0 Gene Product 17 CENP-B_dimeris PF09026.10 EPS29650.1 - 3 8.3 7.2 6.5 7.2 7.2 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain GRDP-like PF07173.12 EPS29651.1 - 0.0067 17.1 0.0 0.0086 16.7 0.0 1.2 1 0 0 1 1 1 1 Glycine-rich domain-containing protein-like HCMV_UL139 PF12507.8 EPS29651.1 - 0.024 15.0 0.7 0.037 14.4 0.7 1.3 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein AARP2CN PF08142.12 EPS29651.1 - 0.16 12.1 0.4 0.26 11.4 0.4 1.3 1 0 0 1 1 1 0 AARP2CN (NUC121) domain Pim PF16765.5 EPS29651.1 - 0.17 12.1 0.2 6.4 7.0 0.2 2.2 1 1 0 1 1 1 0 Pesticin immunity protein DUF3712 PF12505.8 EPS29652.1 - 9.7e-36 122.8 0.2 2.4e-35 121.5 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) Gmad2 PF10648.9 EPS29652.1 - 0.0023 18.1 0.1 0.017 15.4 0.0 2.4 3 0 0 3 3 3 1 Immunoglobulin-like domain of bacterial spore germination LEA_2 PF03168.13 EPS29652.1 - 0.021 15.3 0.7 6.3 7.4 0.1 2.4 2 0 0 2 2 2 0 Late embryogenesis abundant protein NADH_dehy_S2_C PF06444.11 EPS29652.1 - 0.14 12.7 0.1 0.39 11.3 0.1 1.8 1 0 0 1 1 1 0 NADH dehydrogenase subunit 2 C-terminus MFS_1 PF07690.16 EPS29653.1 - 4.9e-29 101.4 40.1 2.7e-24 85.8 17.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.25 EPS29654.1 - 6.4e-29 100.8 0.0 8.4e-29 100.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS29654.1 - 2.8e-26 92.5 0.0 4.3e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPS29654.1 - 1.4e-05 25.1 0.1 0.00018 21.5 0.0 2.5 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 EPS29654.1 - 0.09 12.2 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family FAD_binding_3 PF01494.19 EPS29655.1 - 1.5e-13 50.8 5.1 4.3e-12 45.9 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EPS29655.1 - 0.00054 20.1 1.2 0.0016 18.6 1.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EPS29655.1 - 0.00094 18.5 0.1 0.015 14.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EPS29655.1 - 0.013 14.5 0.0 0.71 8.9 0.0 2.2 2 0 0 2 2 2 0 Squalene epoxidase DAO PF01266.24 EPS29655.1 - 0.017 14.7 3.8 0.028 14.0 2.4 1.9 1 1 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EPS29655.1 - 0.046 13.7 0.9 2.1 8.3 0.3 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.14 EPS29655.1 - 0.82 8.4 2.8 1.5 7.6 0.1 2.2 2 1 0 2 2 2 0 Tryptophan halogenase FKBP26_C PF18046.1 EPS29656.1 - 0.14 12.3 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 FKBP26_C-terminal AAA_11 PF13086.6 EPS29659.1 - 3.3e-62 210.6 1.0 6.2e-62 209.7 1.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 EPS29659.1 - 2.5e-56 190.5 0.0 8.8e-56 188.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EPS29659.1 - 1.3e-13 51.1 0.3 6.7e-12 45.5 0.3 2.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EPS29659.1 - 1.1e-10 42.0 0.1 3.5e-10 40.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EPS29659.1 - 3.2e-08 33.6 0.1 0.023 14.5 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 EPS29659.1 - 1.4e-06 27.8 0.5 1.1e-05 24.8 0.5 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 EPS29659.1 - 3.2e-06 27.3 0.0 9.1e-06 25.8 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.16 EPS29659.1 - 3.5e-06 26.6 0.1 0.027 13.9 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein Helicase_RecD PF05127.14 EPS29659.1 - 9.4e-06 25.6 0.0 0.011 15.6 0.0 2.4 2 0 0 2 2 2 2 Helicase UvrD-helicase PF00580.21 EPS29659.1 - 1.1e-05 25.1 1.2 2.7e-05 23.9 0.1 2.0 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 EPS29659.1 - 3.3e-05 24.2 0.2 0.00024 21.4 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EPS29659.1 - 0.0017 18.1 0.0 0.0034 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 EPS29659.1 - 0.0018 18.0 0.2 0.021 14.6 0.2 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase Flavi_DEAD PF07652.14 EPS29659.1 - 0.0024 17.9 1.7 0.0074 16.3 0.1 2.5 3 0 0 3 3 3 1 Flavivirus DEAD domain T2SSE PF00437.20 EPS29659.1 - 0.0024 17.0 0.0 0.0048 16.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.29 EPS29659.1 - 0.0078 16.6 0.3 0.053 14.0 0.3 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.9 EPS29659.1 - 0.0078 15.2 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain UvrD_C_2 PF13538.6 EPS29659.1 - 0.009 15.8 0.0 0.24 11.2 0.0 2.4 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_5 PF07728.14 EPS29659.1 - 0.011 15.7 0.0 0.094 12.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_10 PF12846.7 EPS29659.1 - 0.011 14.6 0.1 0.018 14.0 0.1 1.2 1 0 0 1 1 1 0 AAA-like domain IstB_IS21 PF01695.17 EPS29659.1 - 0.012 15.4 0.1 0.063 13.0 0.0 2.2 2 1 0 2 2 2 0 IstB-like ATP binding protein AAA_16 PF13191.6 EPS29659.1 - 0.012 16.0 0.0 0.03 14.7 0.0 1.9 1 1 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 EPS29659.1 - 0.025 13.9 0.8 2.4 7.4 0.0 2.7 2 1 1 3 3 3 0 FtsK/SpoIIIE family AAA_25 PF13481.6 EPS29659.1 - 0.026 14.1 0.0 0.15 11.6 0.0 2.3 2 1 0 2 2 2 0 AAA domain UvrD_C PF13361.6 EPS29659.1 - 0.035 13.5 0.0 15 4.8 0.0 2.9 3 0 0 3 3 3 0 UvrD-like helicase C-terminal domain AAA_31 PF13614.6 EPS29659.1 - 0.049 13.6 0.0 4.4 7.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.14 EPS29659.1 - 0.051 12.7 0.0 4.2 6.4 0.0 2.4 2 1 0 2 2 2 0 PIF1-like helicase NTPase_1 PF03266.15 EPS29659.1 - 0.095 12.6 0.4 3.7 7.4 0.0 2.5 2 0 0 2 2 2 0 NTPase SRP54 PF00448.22 EPS29659.1 - 0.11 12.1 0.1 7 6.2 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain HEM4 PF02602.15 EPS29659.1 - 0.11 11.8 0.1 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Uroporphyrinogen-III synthase HemD ABC_tran PF00005.27 EPS29659.1 - 0.12 12.9 0.0 0.27 11.8 0.0 1.7 1 1 0 1 1 1 0 ABC transporter TK PF00265.18 EPS29659.1 - 0.12 12.2 0.1 3.2 7.6 0.0 2.5 2 1 0 2 2 2 0 Thymidine kinase Rad17 PF03215.15 EPS29659.1 - 0.19 11.7 0.1 6 6.7 0.0 2.3 1 1 1 2 2 2 0 Rad17 P-loop domain 4HB_MCP_1 PF12729.7 EPS29659.1 - 0.32 10.5 1.6 0.29 10.6 0.2 1.6 2 0 0 2 2 1 0 Four helix bundle sensory module for signal transduction HhH-GPD PF00730.25 EPS29660.1 - 1.5e-17 64.0 0.0 6.1e-17 62.0 0.0 2.0 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EPS29660.1 - 1e-07 31.4 0.0 4.6e-07 29.4 0.0 2.2 2 0 0 2 2 2 1 Helix-hairpin-helix motif UQ_con PF00179.26 EPS29661.1 - 8.9e-42 142.1 0.0 9.9e-42 141.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EPS29661.1 - 2.5e-05 24.0 0.0 4.1e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Prokaryotic E2 family B UFC1 PF08694.11 EPS29661.1 - 0.031 13.9 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.22 EPS29661.1 - 0.14 12.4 0.1 0.22 11.8 0.1 1.3 1 0 0 1 1 1 0 RWD domain Apt1 PF10351.9 EPS29662.1 - 3.7 6.3 12.5 5.2 5.8 12.5 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Tyrosinase PF00264.20 EPS29664.1 - 3.5e-50 171.3 2.0 4.1e-50 171.1 2.0 1.0 1 0 0 1 1 1 1 Common central domain of tyrosinase PBP PF01161.20 EPS29665.1 - 1.3e-17 64.3 0.0 1.7e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein FA_hydroxylase PF04116.13 EPS29666.1 - 7.8e-23 81.3 18.2 1.2e-22 80.6 15.7 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily HPS6 PF15702.5 EPS29666.1 - 0.017 13.2 0.0 0.019 13.0 0.0 1.1 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 6 protein Glyco_hydro_72 PF03198.14 EPS29668.1 - 1.4e-136 454.9 3.8 1.8e-136 454.6 3.8 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 EPS29668.1 - 3.3e-06 26.7 0.1 4.1e-05 23.2 0.1 2.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) HMGL-like PF00682.19 EPS29669.1 - 4.5e-44 151.0 0.0 5.7e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 HMGL-like RPN2_C PF18004.1 EPS29669.1 - 2.1 8.2 8.7 3.3 7.6 8.7 1.2 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Copper-fist PF00649.18 EPS29671.1 - 1.2e-22 79.0 3.3 2e-22 78.4 3.3 1.3 1 0 0 1 1 1 1 Copper fist DNA binding domain PAP1 PF08601.10 EPS29671.1 - 0.12 12.0 16.2 0.17 11.6 16.2 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 SH3_9 PF14604.6 EPS29672.1 - 4.4e-24 84.1 0.7 2.2e-13 49.8 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.23 EPS29672.1 - 2.7e-23 82.1 0.0 2.7e-23 82.1 0.0 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 EPS29672.1 - 3.6e-18 64.9 0.9 1.1e-08 34.6 0.0 2.7 3 0 0 3 3 3 2 SH3 domain C1_1 PF00130.22 EPS29672.1 - 2.6e-15 56.1 5.0 4.3e-15 55.3 5.0 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_2 PF07653.17 EPS29672.1 - 6.4e-06 25.8 0.1 0.028 14.1 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_10 PF17902.1 EPS29672.1 - 0.00011 22.2 0.1 0.23 11.6 0.0 3.2 3 0 0 3 3 3 2 SH3 domain FAM184 PF15665.5 EPS29672.1 - 0.0059 16.4 6.9 0.0059 16.4 6.9 2.5 3 0 0 3 3 3 1 Family with sequence similarity 184, A and B C1_2 PF03107.16 EPS29672.1 - 0.01 16.1 4.1 0.018 15.3 4.1 1.4 1 0 0 1 1 1 0 C1 domain SH3_3 PF08239.11 EPS29672.1 - 0.054 13.8 1.4 0.4 11.0 0.2 2.8 3 0 0 3 3 3 0 Bacterial SH3 domain DUF3496 PF12001.8 EPS29672.1 - 1.2 9.5 9.3 3.9 7.9 1.9 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3496) DEAD PF00270.29 EPS29674.1 - 1.3e-29 103.2 0.0 3.6e-29 101.8 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPS29674.1 - 6.8e-22 77.9 0.1 1.5e-21 76.8 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 EPS29674.1 - 0.042 13.5 0.1 0.34 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 EPS29674.1 - 0.067 12.6 0.0 0.21 11.0 0.0 1.8 1 0 0 1 1 1 0 Bacterial TniB protein GABP-alpha PF11620.8 EPS29674.1 - 0.15 12.3 0.0 0.54 10.5 0.0 1.9 2 0 0 2 2 2 0 GA-binding protein alpha chain Fungal_trans PF04082.18 EPS29676.1 - 7.9e-09 34.9 0.1 1.5e-08 34.0 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS29676.1 - 3.5e-07 30.2 7.9 6.7e-07 29.3 7.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GTP_CH_N PF12471.8 EPS29677.1 - 1.9e-90 301.8 0.0 2.7e-90 301.3 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.20 EPS29677.1 - 1.7e-17 63.5 0.0 2.4e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II NTP_transf_9 PF04248.12 EPS29677.1 - 0.15 12.0 0.0 0.37 10.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF427) adh_short PF00106.25 EPS29678.1 - 3e-32 111.7 0.0 4.3e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS29678.1 - 6.3e-19 68.5 0.0 8.1e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPS29678.1 - 3.2e-06 27.2 0.0 5.3e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 EPS29678.1 - 0.00047 20.4 0.1 0.001 19.3 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 EPS29678.1 - 0.0017 18.9 0.0 0.0031 18.1 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EPS29678.1 - 0.0028 17.7 0.0 0.0045 17.0 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.21 EPS29678.1 - 0.0045 16.5 0.0 0.053 13.0 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EPS29678.1 - 0.016 15.1 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding DUF1776 PF08643.10 EPS29678.1 - 0.027 13.8 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NAD_binding_2 PF03446.15 EPS29678.1 - 0.12 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Eno-Rase_NADH_b PF12242.8 EPS29678.1 - 0.13 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ApbA PF02558.16 EPS29678.1 - 0.14 11.8 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ADH_zinc_N PF00107.26 EPS29679.1 - 4.7e-13 49.3 0.0 4.8e-12 46.0 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPS29679.1 - 6.7e-06 26.0 0.1 6.4e-05 22.8 0.1 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EPS29679.1 - 0.0004 21.4 0.0 0.0012 19.8 0.0 1.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase Abhydrolase_3 PF07859.13 EPS29680.1 - 1.3e-15 57.8 0.0 1.6e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EPS29680.1 - 4.3e-08 32.4 0.0 7.6e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 EPS29680.1 - 0.0028 17.1 0.0 0.016 14.7 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.13 EPS29681.1 - 1.3e-32 113.2 0.0 3.9e-32 111.6 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Ferric_reduct PF01794.19 EPS29682.1 - 6.2e-21 74.8 11.5 1.8e-20 73.3 11.5 1.9 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EPS29682.1 - 1.1e-15 58.1 0.0 2.6e-15 56.9 0.0 1.7 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EPS29682.1 - 5.1e-11 42.6 0.0 2e-06 27.8 0.0 2.6 2 0 0 2 2 2 2 FAD-binding domain DUF2014 PF09427.10 EPS29683.1 - 3.9e-103 344.4 1.0 5.5e-103 343.9 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.26 EPS29683.1 - 2.2e-18 65.9 0.4 6.5e-18 64.4 0.4 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ZapB PF06005.12 EPS29683.1 - 0.036 14.5 1.1 0.1 13.1 0.1 2.1 2 0 0 2 2 2 0 Cell division protein ZapB TSC22 PF01166.18 EPS29683.1 - 0.37 11.1 2.0 1 9.7 0.6 2.1 2 0 0 2 2 2 0 TSC-22/dip/bun family PRKG1_interact PF15898.5 EPS29683.1 - 0.9 10.5 5.0 15 6.5 5.0 2.5 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain E1-E2_ATPase PF00122.20 EPS29684.1 - 2.2e-42 144.6 8.5 2e-31 108.9 0.0 3.5 2 1 1 3 3 3 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EPS29684.1 - 3.9e-27 95.1 2.1 3.9e-27 95.1 2.1 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EPS29684.1 - 3.1e-18 66.8 0.0 2e-17 64.2 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EPS29684.1 - 2.4e-17 62.4 0.1 6.7e-17 60.9 0.1 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EPS29684.1 - 6.8e-12 45.3 0.0 1.4e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EPS29684.1 - 3.3e-07 30.3 1.6 5e-06 26.4 0.8 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EPS29684.1 - 0.01 16.3 0.1 0.022 15.2 0.1 1.6 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF2463 PF09591.10 EPS29684.1 - 0.065 13.1 1.7 0.22 11.4 1.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2463) RNase_PH PF01138.21 EPS29685.1 - 0.011 16.2 0.0 0.016 15.7 0.0 1.3 1 0 0 1 1 1 0 3' exoribonuclease family, domain 1 NAD_kinase PF01513.21 EPS29687.1 - 2e-78 263.5 0.0 2.7e-78 263.2 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase GAF_2 PF13185.6 EPS29688.1 - 5.8e-13 49.3 0.0 8.6e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 EPS29688.1 - 5.2e-09 36.8 0.0 6.1e-09 36.6 0.0 1.4 1 1 0 1 1 1 1 GAF domain GAF_3 PF13492.6 EPS29688.1 - 7.6e-05 23.1 0.0 0.0001 22.6 0.0 1.2 1 0 0 1 1 1 1 GAF domain AA_permease_2 PF13520.6 EPS29690.1 - 5.4e-58 196.8 46.8 6.7e-58 196.5 46.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPS29690.1 - 9.2e-19 67.4 43.2 1.2e-18 67.0 43.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF5362 PF17319.2 EPS29690.1 - 0.0049 16.7 0.3 0.0049 16.7 0.3 3.6 4 0 0 4 4 4 1 Family of unknown function (DUF5362) Epiglycanin_C PF14654.6 EPS29690.1 - 0.56 10.3 4.2 0.52 10.4 0.2 2.6 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region Phage_holin_1 PF04531.13 EPS29690.1 - 2.3 8.8 6.6 3.6 8.2 0.0 3.7 3 1 1 4 4 4 0 Bacteriophage holin adh_short PF00106.25 EPS29691.1 - 2.4e-54 183.8 0.3 3.2e-54 183.4 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS29691.1 - 1.8e-52 178.2 1.0 2.1e-52 178.0 1.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPS29691.1 - 1.2e-14 54.6 0.1 1.9e-14 54.0 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPS29691.1 - 9.4e-06 25.3 0.0 1.3e-05 24.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 EPS29691.1 - 1.2e-05 25.3 0.0 2.4e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EPS29691.1 - 0.00024 20.2 0.0 0.00033 19.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EPS29691.1 - 0.0012 18.0 0.0 0.0016 17.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EPS29691.1 - 0.0021 17.5 0.0 0.0032 16.9 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase THF_DHG_CYH_C PF02882.19 EPS29691.1 - 0.003 16.9 0.1 0.016 14.5 0.1 1.9 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TrkA_N PF02254.18 EPS29691.1 - 0.0065 16.7 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain Methyltransf_12 PF08242.12 EPS29691.1 - 0.008 16.9 0.0 0.015 16.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain F420_oxidored PF03807.17 EPS29691.1 - 0.0089 16.6 0.1 0.018 15.6 0.1 1.6 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.17 EPS29691.1 - 0.011 14.8 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Methyltransf_25 PF13649.6 EPS29691.1 - 0.017 15.8 0.0 0.035 14.8 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain NAD_binding_7 PF13241.6 EPS29691.1 - 0.022 15.2 0.0 0.038 14.4 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.16 EPS29691.1 - 0.031 13.9 0.0 0.059 13.0 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AdoHcyase_NAD PF00670.21 EPS29691.1 - 0.04 14.0 0.9 0.087 12.9 0.1 1.9 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_10 PF13460.6 EPS29691.1 - 0.099 12.5 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Shikimate_DH PF01488.20 EPS29691.1 - 0.14 12.2 0.2 0.51 10.4 0.1 2.0 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase UPF0561 PF10573.9 EPS29692.1 - 0.094 12.8 0.4 0.094 12.8 0.4 2.5 3 1 0 3 3 3 0 Uncharacterised protein family UPF0561 Mito_carr PF00153.27 EPS29693.1 - 3.4e-39 132.7 0.4 9.1e-20 70.4 0.0 2.5 2 0 0 2 2 2 2 Mitochondrial carrier protein Anp1 PF03452.14 EPS29694.1 - 1.4e-105 352.5 0.0 1.7e-105 352.2 0.0 1.1 1 0 0 1 1 1 1 Anp1 DUF2615 PF11027.8 EPS29694.1 - 0.031 14.4 0.0 0.062 13.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) Zip PF02535.22 EPS29695.1 - 8e-60 202.8 8.4 2e-59 201.5 8.4 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter DUF456 PF04306.13 EPS29695.1 - 2.2 8.5 17.0 20 5.5 11.1 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF456) Nop16 PF09420.10 EPS29696.1 - 3e-69 233.3 13.9 3.4e-69 233.1 13.9 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Pex24p PF06398.11 EPS29697.1 - 2.4e-86 290.0 0.0 3.1e-86 289.6 0.0 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3292 PF11696.8 EPS29697.1 - 0.081 11.3 2.1 0.61 8.4 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3292) Pkinase PF00069.25 EPS29698.1 - 9.8e-54 182.5 0.0 1.4e-53 182.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS29698.1 - 2e-18 66.6 0.0 3.3e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EPS29698.1 - 0.052 13.5 0.0 0.48 10.3 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family COPIIcoated_ERV PF07970.12 EPS29700.1 - 3.8e-36 125.0 0.0 7.8e-36 124.0 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EPS29700.1 - 3e-25 88.4 0.0 6.8e-25 87.2 0.0 1.6 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Filament PF00038.21 EPS29701.1 - 2.3e-06 27.5 30.6 2.3e-06 27.5 30.6 4.3 4 2 0 4 4 4 1 Intermediate filament protein ATG16 PF08614.11 EPS29701.1 - 0.0015 18.8 28.3 0.0015 18.8 28.3 6.3 3 2 2 5 5 5 1 Autophagy protein 16 (ATG16) DUF4200 PF13863.6 EPS29701.1 - 0.0028 18.1 14.4 0.0028 18.1 14.4 6.8 4 2 1 5 5 5 1 Domain of unknown function (DUF4200) PRKG1_interact PF15898.5 EPS29701.1 - 0.0031 18.4 6.2 0.0031 18.4 6.2 6.1 3 1 4 7 7 7 1 cGMP-dependent protein kinase interacting domain ADIP PF11559.8 EPS29701.1 - 0.015 15.4 7.6 0.015 15.4 7.6 6.6 4 2 3 7 7 7 0 Afadin- and alpha -actinin-Binding FAM76 PF16046.5 EPS29701.1 - 0.37 10.1 39.1 0.068 12.5 0.4 4.1 3 1 1 4 4 4 0 FAM76 protein TSC22 PF01166.18 EPS29701.1 - 0.86 10.0 0.0 0.86 10.0 0.0 5.8 6 0 0 6 6 6 0 TSC-22/dip/bun family DUF812 PF05667.11 EPS29701.1 - 1.2 7.9 40.2 0.0066 15.4 29.5 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF812) TMP_2 PF06791.13 EPS29701.1 - 7.9 6.1 9.2 0.84 9.3 3.8 2.2 2 0 0 2 2 2 0 Prophage tail length tape measure protein SOGA PF11365.8 EPS29701.1 - 8.8 7.5 47.4 0.11 13.6 6.7 5.9 4 2 3 7 7 7 0 Protein SOGA BSP PF04450.12 EPS29702.1 - 0.002 18.0 0.0 0.0034 17.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase of plants and bacteria PDZ_6 PF17820.1 EPS29702.1 - 0.0043 16.9 0.1 0.0087 15.9 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EPS29702.1 - 0.016 15.5 0.0 0.051 13.9 0.0 1.8 2 0 0 2 2 2 0 PDZ domain Peptidase_M61 PF05299.12 EPS29702.1 - 0.11 12.9 0.1 1.1 9.6 0.1 2.3 1 1 0 1 1 1 0 M61 glycyl aminopeptidase DUF2268 PF10026.9 EPS29702.1 - 0.19 11.3 0.0 0.31 10.6 0.0 1.2 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) Vitelline_membr PF10542.9 EPS29704.1 - 0.12 12.2 0.1 0.22 11.4 0.1 1.3 1 0 0 1 1 1 0 Vitelline membrane cysteine-rich region Asparaginase_II PF06089.12 EPS29706.1 - 1.3e-56 192.0 0.1 1.6e-56 191.7 0.1 1.0 1 0 0 1 1 1 1 L-asparaginase II Maf1 PF09174.10 EPS29707.1 - 2.8e-60 203.4 0.0 3.7e-60 203.1 0.0 1.1 1 0 0 1 1 1 1 Maf1 regulator Clat_adaptor_s PF01217.20 EPS29708.1 - 7.2e-53 178.3 1.1 8.5e-53 178.1 1.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PulA_N1 PF17999.1 EPS29708.1 - 0.054 14.2 0.2 0.11 13.2 0.2 1.5 1 1 0 1 1 1 0 Pullulanase N1-terminal domain Fungal_trans_2 PF11951.8 EPS29708.1 - 0.1 11.4 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain PPR_3 PF13812.6 EPS29709.1 - 0.013 15.6 0.0 0.033 14.3 0.0 1.7 1 0 0 1 1 1 0 Pentatricopeptide repeat domain DUF2745 PF10922.8 EPS29709.1 - 0.12 12.6 0.3 0.48 10.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2745) Sugar_tr PF00083.24 EPS29710.1 - 6.9e-20 71.3 27.3 7.4e-18 64.6 27.3 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS29710.1 - 1.8e-12 46.9 18.5 1.5e-07 30.7 2.2 2.9 3 0 0 3 3 3 2 Major Facilitator Superfamily PRELI PF04707.14 EPS29711.1 - 1.6e-24 86.5 0.0 5e-21 75.2 0.0 2.2 2 0 0 2 2 2 2 PRELI-like family Beta-lactamase2 PF13354.6 EPS29711.1 - 0.079 12.5 0.0 0.12 11.9 0.0 1.4 1 1 0 1 1 1 0 Beta-lactamase enzyme family PA_decarbox PF05870.11 EPS29714.1 - 2.9e-10 40.0 0.0 3.4e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) Hydrophobin PF01185.18 EPS29715.1 - 0.32 11.7 9.9 1.4 9.6 1.1 2.2 1 1 1 2 2 2 0 Fungal hydrophobin Metallophos PF00149.28 EPS29716.1 - 1.7e-07 32.0 1.7 3.4e-07 31.0 1.7 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MARVEL PF01284.23 EPS29717.1 - 5.6e-27 94.5 15.6 6.6e-27 94.3 15.6 1.0 1 0 0 1 1 1 1 Membrane-associating domain MgtE PF01769.16 EPS29717.1 - 4.1 7.8 10.8 1.9 8.9 7.2 2.0 2 0 0 2 2 2 0 Divalent cation transporter Pex24p PF06398.11 EPS29718.1 - 7.4e-06 25.2 5.8 1.3e-05 24.4 5.8 1.4 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF4476 PF14771.6 EPS29718.1 - 0.00037 20.7 0.1 0.00086 19.6 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4476) Mis14 PF08641.12 EPS29719.1 - 1.7e-29 102.8 5.1 1.8e-29 102.8 2.5 2.4 3 1 0 3 3 3 1 Kinetochore protein Mis14 like RP-C_C PF11800.8 EPS29719.1 - 0.055 13.5 5.4 0.085 12.9 5.4 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Nbl1_Borealin_N PF10444.9 EPS29719.1 - 0.13 12.0 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal LPP PF04728.13 EPS29719.1 - 0.19 12.1 1.7 2 8.9 0.1 2.9 2 1 0 2 2 2 0 Lipoprotein leucine-zipper CDC45 PF02724.14 EPS29719.1 - 0.45 8.8 11.1 0.61 8.3 11.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 EPS29719.1 - 2.5 6.1 3.6 2.5 6.1 3.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CRAL_TRIO PF00650.20 EPS29720.1 - 1.4e-35 122.4 0.0 2.2e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EPS29720.1 - 7.9e-08 32.4 0.1 1.8e-07 31.2 0.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EPS29720.1 - 0.00074 19.7 0.0 0.0014 18.8 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RasGAP PF00616.19 EPS29721.1 - 2.4e-59 200.6 0.0 2.4e-59 200.6 0.0 2.3 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 EPS29721.1 - 3e-31 108.4 2.7 3e-31 108.4 2.7 2.5 2 0 0 2 2 2 1 RasGAP C-terminus MarR PF01047.22 EPS29721.1 - 0.11 12.5 0.1 0.53 10.2 0.1 2.2 2 0 0 2 2 2 0 MarR family Promethin PF16015.5 EPS29724.1 - 3.6e-13 49.3 13.9 6.2e-13 48.6 13.9 1.3 1 0 0 1 1 1 1 Promethin Acetyltransf_1 PF00583.25 EPS29725.1 - 7.4e-19 68.1 0.0 1e-18 67.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EPS29725.1 - 9.9e-12 44.9 0.0 1.4e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPS29725.1 - 1.6e-11 44.0 0.0 2.9e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EPS29725.1 - 1.1e-10 41.8 0.0 1.7e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EPS29725.1 - 6.6e-08 33.3 0.0 8.9e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EPS29725.1 - 3.3e-06 26.9 0.0 4.8e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EPS29725.1 - 8.5e-06 25.9 0.0 1.8e-05 24.8 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EPS29725.1 - 0.00078 19.6 0.0 0.001 19.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EPS29725.1 - 0.0028 17.8 0.0 0.0057 16.8 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase PanZ PF12568.8 EPS29725.1 - 0.0046 16.7 0.1 0.007 16.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ LCAT PF02450.15 EPS29726.1 - 2.1e-106 356.4 0.0 2.5e-106 356.2 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF900 PF05990.12 EPS29726.1 - 0.016 14.7 0.0 0.026 14.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Lipase_2 PF01674.18 EPS29726.1 - 0.031 13.8 0.0 0.07 12.6 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 2) PAP2_3 PF14378.6 EPS29727.1 - 3.9e-24 85.4 14.1 3.9e-24 85.4 14.1 2.0 1 1 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 EPS29727.1 - 4.8e-11 42.6 2.4 4.8e-11 42.6 2.4 2.1 2 0 0 2 2 2 1 PAP2 superfamily Fungal_trans PF04082.18 EPS29728.1 - 1.3e-09 37.5 0.0 3.6e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS29728.1 - 5e-07 29.7 10.5 1e-06 28.7 10.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amino_oxidase PF01593.24 EPS29729.1 - 9.2e-52 176.8 0.3 1.1e-51 176.6 0.3 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EPS29729.1 - 1.4e-12 47.6 0.3 9.2e-12 45.0 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EPS29729.1 - 8.4e-08 32.2 0.1 2e-07 30.9 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EPS29729.1 - 1.8e-05 24.3 0.1 0.00017 21.1 0.0 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPS29729.1 - 2.3e-05 23.8 0.0 4.1e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EPS29729.1 - 2.4e-05 23.7 0.1 4.6e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 EPS29729.1 - 0.00013 21.2 0.2 0.00023 20.4 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EPS29729.1 - 0.00082 18.2 0.0 0.0016 17.2 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 EPS29729.1 - 0.00098 18.5 0.2 0.0056 16.0 0.3 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 EPS29729.1 - 0.0043 17.6 0.1 0.01 16.3 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EPS29729.1 - 0.0071 15.4 0.1 0.012 14.7 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein GIDA PF01134.22 EPS29729.1 - 0.0078 15.3 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A UDPG_MGDP_dh_N PF03721.14 EPS29729.1 - 0.14 11.7 0.2 0.27 10.8 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain VIT1 PF01988.19 EPS29730.1 - 6.4e-61 206.0 3.1 8.5e-61 205.6 3.1 1.2 1 0 0 1 1 1 1 VIT family PAC2 PF09754.9 EPS29730.1 - 0.073 13.1 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 PAC2 family SLATT_fungal PF18142.1 EPS29730.1 - 0.12 12.3 1.0 0.22 11.5 0.1 1.9 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain FIST PF08495.10 EPS29730.1 - 0.3 11.1 2.3 1.5 8.8 0.0 2.2 1 1 1 2 2 2 0 FIST N domain Phosphoesterase PF04185.14 EPS29731.1 - 2.8e-62 211.0 6.6 5.8e-62 209.9 6.6 1.5 1 1 0 1 1 1 1 Phosphoesterase family GPI-anchored PF10342.9 EPS29732.1 - 4.5e-20 72.2 4.6 4.5e-20 72.2 4.6 2.5 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family fn3 PF00041.21 EPS29732.1 - 0.0018 18.5 0.5 0.0057 17.0 0.5 1.8 1 0 0 1 1 1 1 Fibronectin type III domain PBP3 PF18056.1 EPS29732.1 - 0.29 11.3 0.0 0.29 11.3 0.0 2.9 2 1 0 2 2 2 0 Penicillin Binding Protein 3 Domain Activator_LAG-3 PF11498.8 EPS29732.1 - 0.39 9.6 4.7 0.54 9.2 4.7 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF4614 PF15391.6 EPS29732.1 - 7 6.6 18.9 2.6 8.0 15.4 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4614) SOG2 PF10428.9 EPS29732.1 - 8.5 5.5 21.0 10 5.2 21.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Alpha-amylase PF00128.24 EPS29733.1 - 2.6e-20 73.3 0.0 7.2e-20 71.8 0.0 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 EPS29733.1 - 1.4e-05 23.5 0.0 0.02 13.1 0.0 3.0 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 DUF1939 PF09154.10 EPS29733.1 - 0.11 12.6 2.1 0.15 12.3 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1939) Alpha-amylase PF00128.24 EPS29734.1 - 1.4e-48 166.2 2.9 1.9e-48 165.7 2.9 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.11 EPS29734.1 - 2.8e-32 110.9 0.2 5.2e-32 110.0 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) GHL10 PF02638.15 EPS29734.1 - 0.024 13.7 0.3 0.038 13.1 0.3 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase-like 10 Glyco_transf_5 PF08323.11 EPS29735.1 - 3.8e-16 59.5 0.1 7.2e-16 58.6 0.1 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Alpha-amylase PF00128.24 EPS29735.1 - 6.7e-15 55.5 1.5 3.4e-14 53.2 1.5 2.2 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_trans_1_4 PF13692.6 EPS29735.1 - 7.3e-06 26.5 0.0 1.5e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EPS29735.1 - 2.4e-05 24.0 0.0 5.1e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EPS29735.1 - 0.0071 16.4 0.0 0.023 14.7 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase Family 4 DC_STAMP PF07782.13 EPS29736.1 - 0.004 17.0 0.0 0.0043 16.9 0.0 1.1 1 0 0 1 1 1 1 DC-STAMP-like protein SARAF PF06682.12 EPS29736.1 - 0.012 15.2 0.0 0.012 15.2 0.0 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis AsnA PF03590.15 EPS29736.1 - 0.034 13.9 0.2 0.039 13.7 0.2 1.0 1 0 0 1 1 1 0 Aspartate-ammonia ligase DUF1449 PF07290.11 EPS29736.1 - 0.042 13.5 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) DUF4330 PF14221.6 EPS29736.1 - 0.044 14.0 0.1 0.053 13.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) DUF4199 PF13858.6 EPS29736.1 - 0.061 13.7 0.0 0.07 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Consortin_C PF15281.6 EPS29736.1 - 0.065 13.2 0.2 0.094 12.7 0.1 1.4 1 1 0 1 1 1 0 Consortin C-terminus Pilin_N PF07790.11 EPS29736.1 - 0.073 14.0 0.1 0.1 13.6 0.1 1.2 1 0 0 1 1 1 0 Archaeal Type IV pilin, N-terminal FeoB_associated PF12669.7 EPS29736.1 - 0.074 13.5 1.6 0.13 12.7 1.6 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Chordopox_A13L PF05961.11 EPS29736.1 - 0.079 13.2 2.0 0.11 12.7 2.0 1.4 1 1 0 1 1 1 0 Chordopoxvirus A13L protein LapA_dom PF06305.11 EPS29736.1 - 0.093 12.6 0.5 0.17 11.7 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain AMPK1_CBM PF16561.5 EPS29737.1 - 3.8e-15 55.9 0.2 7.6e-15 54.9 0.2 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM53 PF16760.5 EPS29737.1 - 0.047 14.3 0.3 0.11 13.1 0.3 1.6 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) cNMP_binding PF00027.29 EPS29738.1 - 4.8e-39 132.3 0.0 2.9e-20 72.1 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain 2OG-FeII_Oxy_3 PF13640.6 EPS29739.1 - 5.9e-10 39.9 0.0 9.6e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 EPS29739.1 - 0.017 15.6 0.0 0.032 14.7 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Forkhead PF00250.18 EPS29740.1 - 6.8e-18 64.7 0.0 1.4e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 EPS29740.1 - 2.6e-06 27.7 0.0 4.9e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 FHA domain Cyclin PF08613.11 EPS29742.1 - 4.7e-15 56.3 0.2 9.4e-15 55.3 0.2 1.5 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EPS29742.1 - 0.0016 18.2 0.0 0.0016 18.2 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain BORG_CEP PF14957.6 EPS29742.1 - 0.26 12.5 2.1 0.46 11.7 0.5 2.0 2 0 0 2 2 2 0 Cdc42 effector SelP_N PF04592.14 EPS29742.1 - 4 6.8 11.4 7.4 5.9 11.4 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region TFIIA PF03153.13 EPS29742.1 - 5.8 6.8 10.6 0.26 11.2 5.2 1.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit His_Phos_1 PF00300.22 EPS29743.1 - 6.4e-31 107.6 0.0 1.5e-30 106.3 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 EPS29743.1 - 0.00053 19.4 0.0 0.0013 18.2 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) P5-ATPase PF12409.8 EPS29743.1 - 0.068 13.3 0.1 0.068 13.3 0.1 2.3 2 1 0 2 2 2 0 P5-type ATPase cation transporter GCP5-Mod21 PF14609.6 EPS29743.1 - 0.16 10.3 1.8 0.23 9.8 1.8 1.1 1 0 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 Dor1 PF04124.12 EPS29744.1 - 4e-56 190.1 4.3 2e-44 151.7 2.6 2.4 1 1 0 2 2 2 2 Dor1-like family Vps51 PF08700.11 EPS29744.1 - 5.9e-05 23.1 0.8 0.00019 21.5 0.8 2.0 1 0 0 1 1 1 1 Vps51/Vps67 LPP PF04728.13 EPS29744.1 - 0.035 14.5 0.1 0.035 14.5 0.1 2.5 3 0 0 3 3 3 0 Lipoprotein leucine-zipper GAS PF13851.6 EPS29744.1 - 0.061 12.7 1.3 0.09 12.1 0.2 1.8 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-H PF05837.12 EPS29744.1 - 0.82 10.1 4.0 0.71 10.3 0.8 2.6 3 0 0 3 3 3 0 Centromere protein H (CENP-H) Fez1 PF06818.15 EPS29744.1 - 1.3 9.5 4.8 0.32 11.4 0.8 1.9 2 1 0 2 2 2 0 Fez1 EAF PF09816.9 EPS29745.1 - 1.1e-20 73.9 0.3 2.1e-20 73.0 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Cyclin_N PF00134.23 EPS29746.1 - 1.3e-14 54.0 2.1 1.9e-14 53.5 0.8 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EPS29746.1 - 0.00024 21.2 0.1 0.0022 18.1 0.0 2.3 2 1 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_C_2 PF16899.5 EPS29746.1 - 0.086 13.2 0.0 0.28 11.6 0.0 1.9 2 0 0 2 2 2 0 Cyclin C-terminal domain DUF1422 PF07226.11 EPS29746.1 - 0.21 11.6 0.1 0.37 10.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1422) TFIIB PF00382.19 EPS29746.1 - 0.3 11.1 4.3 2.2 8.4 0.9 2.6 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Pkinase PF00069.25 EPS29747.1 - 2.3e-66 223.9 0.0 2.8e-66 223.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS29747.1 - 9.3e-29 100.5 0.0 1.4e-28 99.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EPS29747.1 - 0.012 14.4 0.1 0.016 14.0 0.1 1.5 1 1 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 EPS29747.1 - 0.013 14.4 0.3 0.025 13.6 0.3 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Kinase-like PF14531.6 EPS29747.1 - 0.086 12.1 0.3 0.4 9.9 0.0 2.0 1 1 0 2 2 2 0 Kinase-like FolB PF02152.18 EPS29748.1 - 2e-25 89.5 0.0 2.3e-21 76.4 0.2 2.3 2 0 0 2 2 2 2 Dihydroneopterin aldolase RRM_1 PF00076.22 EPS29749.1 - 3.6e-24 84.4 0.1 2.3e-13 49.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EPS29749.1 - 0.00071 19.4 0.0 0.012 15.4 0.0 2.1 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_3 PF08777.11 EPS29749.1 - 0.016 15.2 0.0 0.86 9.7 0.0 2.1 2 0 0 2 2 2 0 RNA binding motif DbpA PF03880.15 EPS29749.1 - 0.21 11.6 0.1 1.6 8.7 0.0 2.1 2 0 0 2 2 2 0 DbpA RNA binding domain ETF_QO PF05187.13 EPS29750.1 - 2.3e-48 162.6 0.7 3.6e-48 162.0 0.7 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 EPS29750.1 - 2.2e-07 30.8 0.5 0.00051 19.7 0.5 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EPS29750.1 - 8.3e-07 29.2 0.0 3e-06 27.4 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EPS29750.1 - 2.3e-06 26.9 0.3 0.0019 17.3 0.7 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EPS29750.1 - 4.9e-06 26.0 0.0 0.00014 21.2 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPS29750.1 - 1.7e-05 25.2 0.1 0.031 14.9 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EPS29750.1 - 4.1e-05 23.1 0.0 6.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EPS29750.1 - 0.00042 19.7 0.0 0.00069 19.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EPS29750.1 - 0.0005 18.9 0.4 0.00076 18.3 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.6 EPS29750.1 - 0.00084 19.4 0.2 0.0035 17.3 0.2 2.1 2 1 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 EPS29750.1 - 0.0023 17.2 0.0 0.0057 15.9 0.1 1.5 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 EPS29750.1 - 0.0068 15.7 0.5 0.01 15.1 0.5 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EPS29750.1 - 0.0084 15.0 0.1 0.24 10.2 0.1 2.1 1 1 1 2 2 2 1 Tryptophan halogenase Fer4_7 PF12838.7 EPS29750.1 - 0.014 16.0 1.0 0.034 14.7 1.0 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Amino_oxidase PF01593.24 EPS29750.1 - 0.033 13.5 0.0 0.069 12.4 0.0 1.5 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.12 EPS29750.1 - 0.083 11.9 0.4 0.12 11.4 0.4 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 EPS29750.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EPS29750.1 - 0.13 11.3 0.1 0.2 10.7 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Fer4_2 PF12797.7 EPS29750.1 - 0.16 12.2 0.7 0.39 10.9 0.7 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain TBP PF00352.21 EPS29752.1 - 2.7e-67 222.7 0.1 9.3e-33 112.0 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 EPS29752.1 - 5.2e-05 23.3 0.0 0.23 11.6 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 EPS29752.1 - 0.13 12.1 0.1 0.69 9.8 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) DAO PF01266.24 EPS29753.1 - 2.6e-43 149.0 1.3 3e-43 148.7 1.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPS29753.1 - 2.1e-06 27.2 0.0 0.07 12.4 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EPS29753.1 - 5.9e-05 23.1 0.1 0.21 11.5 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EPS29753.1 - 7.9e-05 22.8 0.0 0.00023 21.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 EPS29753.1 - 8.2e-05 21.6 0.1 0.0044 15.9 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase GIDA PF01134.22 EPS29753.1 - 0.00029 20.1 0.0 0.00084 18.5 0.0 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EPS29753.1 - 0.001 18.3 0.9 0.012 14.7 0.9 2.1 1 1 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 EPS29753.1 - 0.015 14.5 0.0 2.1 7.5 0.0 2.3 2 1 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.12 EPS29753.1 - 0.018 14.1 0.1 0.84 8.6 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.27 EPS29753.1 - 0.031 14.8 0.0 0.072 13.7 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EPS29753.1 - 0.075 12.3 0.0 0.52 9.5 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EPS29753.1 - 0.16 11.1 0.1 0.8 8.8 0.0 1.9 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EPS29753.1 - 0.16 11.2 0.0 0.33 10.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.18 EPS29753.1 - 0.17 12.2 0.0 0.43 10.9 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain Methyltransf_23 PF13489.6 EPS29754.1 - 1.2e-37 129.3 0.0 1.8e-37 128.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPS29754.1 - 2.1e-07 31.6 0.0 4.6e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPS29754.1 - 4.9e-07 30.4 0.1 4.3e-06 27.3 0.1 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS29754.1 - 3.5e-05 24.4 0.0 0.00081 20.0 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPS29754.1 - 0.00015 21.6 0.0 0.00037 20.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain DUF3235 PF11574.8 EPS29754.1 - 1.9 9.4 4.5 15 6.5 1.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3235) YnfE PF17452.2 EPS29755.1 - 0.18 12.1 0.0 2.4 8.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized YnfE-like Fungal_trans PF04082.18 EPS29756.1 - 6.4e-19 68.0 0.1 1.1e-18 67.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS29756.1 - 2.5e-07 30.7 10.3 4.4e-07 29.9 10.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3864 PF12980.7 EPS29757.1 - 0.0082 16.4 0.0 0.025 14.9 0.0 1.8 1 0 0 1 1 1 1 Domain of Unknown Function with PDB structure (DUF3864) HTH_IclR PF09339.10 EPS29757.1 - 0.024 14.5 0.4 1.8 8.4 0.0 3.4 3 0 0 3 3 3 0 IclR helix-turn-helix domain Ndc80_HEC PF03801.13 EPS29759.1 - 1.5e-59 200.0 0.0 3.3e-59 198.9 0.0 1.6 1 0 0 1 1 1 1 HEC/Ndc80p family DUF16 PF01519.16 EPS29759.1 - 0.0027 18.2 6.5 0.0027 18.2 6.5 4.2 3 1 1 4 4 4 1 Protein of unknown function DUF16 DUF812 PF05667.11 EPS29759.1 - 0.019 13.9 38.4 0.2 10.5 22.0 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF812) FlaC_arch PF05377.11 EPS29759.1 - 0.063 13.7 0.4 0.063 13.7 0.4 6.7 6 3 2 8 8 8 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.12 EPS29759.1 - 0.084 13.3 15.4 0.68 10.4 0.8 4.3 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Filament PF00038.21 EPS29759.1 - 0.16 11.5 47.1 0.69 9.4 22.3 2.8 2 1 0 2 2 2 0 Intermediate filament protein Cep57_CLD PF14073.6 EPS29759.1 - 0.22 11.5 39.6 0.04 13.9 19.1 2.4 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 Spc7 PF08317.11 EPS29759.1 - 2.9 6.7 48.0 0.13 11.1 14.1 3.4 2 2 1 3 3 3 0 Spc7 kinetochore protein MtrG PF04210.13 EPS29759.1 - 9.4 6.2 8.4 2.4 8.1 0.3 3.1 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G Pex14_N PF04695.13 EPS29760.1 - 1.2e-42 146.2 0.1 1.2e-42 146.2 0.1 3.3 2 1 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3450 PF11932.8 EPS29760.1 - 0.0037 16.6 1.8 0.0037 16.6 1.8 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3450) Baculo_PEP_C PF04513.12 EPS29760.1 - 0.0039 17.3 0.5 0.012 15.7 0.5 1.8 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Myosin_tail_1 PF01576.19 EPS29760.1 - 0.016 13.0 5.8 0.021 12.6 5.8 1.1 1 0 0 1 1 1 0 Myosin tail DUF3584 PF12128.8 EPS29760.1 - 0.028 12.0 5.9 0.038 11.5 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Tropomyosin PF00261.20 EPS29760.1 - 0.053 12.9 7.1 0.075 12.4 7.1 1.2 1 0 0 1 1 1 0 Tropomyosin FlgN PF05130.12 EPS29760.1 - 0.064 13.8 4.2 0.11 13.0 4.2 1.3 1 0 0 1 1 1 0 FlgN protein EamA PF00892.20 EPS29760.1 - 0.17 12.1 0.0 0.26 11.5 0.0 1.2 1 0 0 1 1 1 0 EamA-like transporter family Golgin_A5 PF09787.9 EPS29760.1 - 0.18 11.2 1.2 0.27 10.6 1.2 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF812 PF05667.11 EPS29760.1 - 0.64 8.8 3.6 1.2 8.0 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF1664 PF07889.12 EPS29760.1 - 5.8 7.0 5.4 0.89 9.6 0.9 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) zf-C4H2 PF10146.9 EPS29760.1 - 10 6.4 9.6 0.48 10.7 2.5 2.3 2 1 0 2 2 2 0 Zinc finger-containing protein Acetyltransf_3 PF13302.7 EPS29762.1 - 1.9e-14 54.5 0.0 2.6e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPS29762.1 - 1.8e-07 31.4 0.0 2.4e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 EPS29762.1 - 0.001 19.2 0.0 0.0014 18.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PrpF PF04303.13 EPS29763.1 - 1.3e-105 353.4 1.0 1.5e-105 353.2 1.0 1.0 1 0 0 1 1 1 1 PrpF protein TTL PF03133.15 EPS29764.1 - 9.2e-56 189.1 0.0 1.4e-55 188.5 0.0 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.17 EPS29764.1 - 1.2e-50 172.0 0.0 1.8e-50 171.4 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.6 EPS29764.1 - 0.0017 17.7 0.0 0.0048 16.2 0.0 1.7 2 0 0 2 2 2 1 YheC/D like ATP-grasp Glyco_trans_4_4 PF13579.6 EPS29764.1 - 0.016 15.7 0.0 0.035 14.5 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Seipin PF06775.14 EPS29765.1 - 1.6e-60 204.6 0.1 2.8e-60 203.8 0.1 1.4 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Not1 PF04054.15 EPS29766.1 - 1.4e-139 465.1 1.2 2.6e-139 464.2 1.2 1.5 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 EPS29766.1 - 4.3e-95 317.4 0.2 1e-94 316.1 0.2 1.7 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 EPS29766.1 - 7.9e-52 175.1 1.2 2e-51 173.8 1.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_TTP_bind PF16417.5 EPS29766.1 - 2.1e-41 141.2 0.0 5.1e-41 139.9 0.0 1.6 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 EPS29766.1 - 1.1e-31 109.9 0.1 3.9e-31 108.2 0.1 2.0 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat Surp PF01805.20 EPS29769.1 - 3.2e-11 43.1 0.0 6.2e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Surp module TMA7 PF09072.10 EPS29770.1 - 7.1e-25 87.6 20.4 7.9e-25 87.5 20.4 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 AGH PF17558.2 EPS29770.1 - 0.12 12.5 0.0 0.13 12.4 0.0 1.0 1 0 0 1 1 1 0 Androgenic gland hormone NTF2 PF02136.20 EPS29771.1 - 2.9e-32 111.7 0.2 3.3e-32 111.6 0.2 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 EPS29771.1 - 0.00092 19.6 0.0 0.0011 19.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Imm58 PF15581.6 EPS29771.1 - 0.062 13.4 0.0 0.075 13.1 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 58 PQ-loop PF04193.14 EPS29772.1 - 3.9e-17 61.8 21.8 4.1e-10 39.3 1.6 3.3 3 1 1 4 4 4 2 PQ loop repeat Ish1 PF10281.9 EPS29773.1 - 7e-89 291.8 21.5 2.4e-14 53.4 0.0 7.5 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein HeH PF12949.7 EPS29773.1 - 2.2e-12 46.4 0.6 0.038 13.7 0.2 5.9 7 0 0 7 7 7 4 HeH/LEM domain SAP PF02037.27 EPS29773.1 - 1.1e-11 44.2 0.0 0.28 11.0 0.0 6.5 6 1 0 6 6 6 3 SAP domain ANAPC2 PF08672.11 EPS29773.1 - 6.9e-05 23.3 0.5 40 4.8 0.0 5.6 6 0 0 6 6 5 0 Anaphase promoting complex (APC) subunit 2 Thymopoietin PF08198.11 EPS29773.1 - 0.00051 19.6 0.1 4.3 7.0 0.1 3.6 3 0 0 3 3 3 1 Thymopoietin protein CPSase_sm_chain PF00988.22 EPS29773.1 - 0.0017 18.2 0.5 5.6 6.8 0.0 4.9 5 1 1 6 6 6 1 Carbamoyl-phosphate synthase small chain, CPSase domain Slx4 PF09494.10 EPS29773.1 - 0.0026 17.7 2.6 92 3.1 0.0 5.8 6 0 0 6 6 6 0 Slx4 endonuclease Phasin PF05597.11 EPS29773.1 - 0.0043 17.1 11.2 1.2 9.1 0.1 4.5 4 1 0 4 4 4 2 Poly(hydroxyalcanoate) granule associated protein (phasin) SAM_2 PF07647.17 EPS29773.1 - 0.05 13.7 4.1 30 4.8 0.3 4.9 5 0 0 5 5 5 0 SAM domain (Sterile alpha motif) YtxH PF12732.7 EPS29773.1 - 0.051 14.1 13.3 4.3 7.9 0.3 4.7 4 1 0 4 4 4 0 YtxH-like protein TilS PF09179.11 EPS29773.1 - 0.18 12.3 4.5 8.4 7.0 0.1 3.9 4 0 0 4 4 4 0 TilS substrate binding domain Cyt-b5 PF00173.28 EPS29774.1 - 8.9e-16 57.8 0.0 1.2e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4519 PF15012.6 EPS29774.1 - 0.12 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Pkinase PF00069.25 EPS29776.1 - 2.3e-52 178.0 0.0 3.1e-52 177.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS29776.1 - 9.7e-25 87.3 0.0 2e-24 86.3 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 EPS29776.1 - 0.053 12.5 0.1 0.084 11.8 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 EPS29776.1 - 0.057 12.2 0.0 0.12 11.1 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase DUF3187 PF11383.8 EPS29778.1 - 0.1 11.8 0.3 0.12 11.6 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3187) Pkinase PF00069.25 EPS29781.1 - 2.5e-53 181.1 0.0 3.2e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS29781.1 - 9.8e-33 113.5 0.0 1.2e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EPS29781.1 - 0.0008 18.8 0.0 0.0021 17.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EPS29781.1 - 0.00091 19.2 0.0 0.01 15.8 0.0 2.3 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EPS29781.1 - 0.033 13.6 0.0 0.05 12.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EPS29781.1 - 0.21 11.1 0.1 0.3 10.6 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase adh_short_C2 PF13561.6 EPS29782.1 - 2.5e-48 164.7 5.0 2.9e-39 135.0 5.8 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPS29782.1 - 8.1e-44 149.4 4.6 9.9e-44 149.1 4.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPS29782.1 - 1.8e-15 57.3 0.8 2.4e-15 56.9 0.8 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EPS29782.1 - 0.0012 18.8 1.1 0.0019 18.1 1.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 EPS29782.1 - 0.027 14.6 2.6 0.047 13.8 2.2 1.5 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Polysacc_synt_2 PF02719.15 EPS29782.1 - 0.031 13.4 0.0 0.044 12.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 2-Hacid_dh_C PF02826.19 EPS29782.1 - 0.053 12.9 0.1 0.084 12.2 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GSIII_N PF12437.8 EPS29782.1 - 0.058 13.1 0.1 0.17 11.6 0.0 1.7 2 0 0 2 2 2 0 Glutamine synthetase type III N terminal Shikimate_DH PF01488.20 EPS29782.1 - 0.1 12.6 0.1 0.2 11.7 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 EPS29782.1 - 0.11 12.0 0.2 0.18 11.3 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ADH_zinc_N PF00107.26 EPS29782.1 - 0.23 11.4 2.8 0.48 10.4 1.5 2.2 2 0 0 2 2 2 0 Zinc-binding dehydrogenase 3HCDH_RFF PF18321.1 EPS29782.1 - 6.5 7.3 7.1 0.56 10.7 2.1 1.8 2 0 0 2 2 2 0 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain Zn_clus PF00172.18 EPS29783.1 - 2.7e-07 30.6 8.1 2.7e-07 30.6 8.1 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3665 PF12427.8 EPS29783.1 - 3.3 7.5 4.9 0.47 10.2 0.5 1.9 2 0 0 2 2 2 0 Branched-chain amino acid aminotransferase HlyIII PF03006.20 EPS29784.1 - 1e-63 215.1 6.7 1.2e-63 214.8 6.7 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF998 PF06197.13 EPS29784.1 - 0.17 11.5 12.6 0.047 13.3 5.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF998) DUF3325 PF11804.8 EPS29784.1 - 1.3 9.2 5.7 0.5 10.5 1.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3325) TssN PF17555.2 EPS29784.1 - 3 7.2 5.0 1.3 8.4 0.2 2.3 2 1 1 3 3 3 0 Type VI secretion system, TssN CSN8_PSD8_EIF3K PF10075.9 EPS29785.1 - 0.00079 19.4 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 EPS29785.1 - 0.02 14.3 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 SAC3/GANP family TPR_19 PF14559.6 EPS29786.1 - 5.2e-07 30.1 6.7 0.00093 19.7 0.6 3.0 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 EPS29786.1 - 0.00046 20.8 3.2 4 8.5 0.0 4.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EPS29786.1 - 0.0015 18.5 0.5 4.9 7.5 0.2 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat Nup84_Nup100 PF04121.13 EPS29786.1 - 0.0032 15.7 0.6 0.0032 15.7 0.6 1.5 2 0 0 2 2 2 1 Nuclear pore protein 84 / 107 Coatomer_E PF04733.14 EPS29786.1 - 0.0049 16.3 0.4 0.0078 15.7 0.4 1.3 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_6 PF13174.6 EPS29786.1 - 0.01 16.4 0.8 48 4.9 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 EPS29786.1 - 0.011 16.0 2.3 0.31 11.3 0.2 3.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_21 PF09976.9 EPS29786.1 - 0.033 13.9 3.3 0.85 9.3 0.6 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain SRP_TPR_like PF17004.5 EPS29786.1 - 0.05 13.6 0.0 0.2 11.7 0.0 1.8 1 1 1 2 2 2 0 Putative TPR-like repeat TPR_4 PF07721.14 EPS29786.1 - 0.051 14.2 8.8 3.8 8.4 0.2 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EPS29786.1 - 0.061 13.5 0.8 6.3 7.1 0.5 2.5 1 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 EPS29786.1 - 0.12 12.2 1.4 6.9 6.7 0.2 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 EPS29786.1 - 0.13 12.5 0.3 73 4.0 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EPS29786.1 - 0.22 11.1 3.3 2.6 7.7 1.6 2.8 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_16 PF13432.6 EPS29786.1 - 0.37 11.5 6.5 6.4 7.5 0.7 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat Glycos_transf_2 PF00535.26 EPS29787.1 - 3.7e-34 118.0 0.0 4.5e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EPS29787.1 - 2.7e-12 47.1 0.0 3.4e-12 46.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EPS29787.1 - 2.9e-06 27.0 0.0 4e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EPS29787.1 - 0.00018 21.0 0.0 0.00027 20.5 0.0 1.3 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 EPS29787.1 - 0.055 13.4 0.0 0.071 13.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family group 2 Glyco_tranf_2_4 PF13704.6 EPS29787.1 - 0.057 13.9 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF1749 PF08538.10 EPS29788.1 - 5.8e-101 337.5 0.0 7.1e-101 337.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Nop14 PF04147.12 EPS29789.1 - 1.8 6.6 17.6 2.5 6.2 17.6 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EPS29789.1 - 2.4 6.4 17.8 3.5 5.8 17.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.22 EPS29789.1 - 6.2 5.9 5.8 9.8 5.3 5.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter BUD22 PF09073.10 EPS29789.1 - 9 5.5 24.3 17 4.6 24.3 1.3 1 0 0 1 1 1 0 BUD22 FCH PF00611.23 EPS29791.1 - 6.7e-15 55.1 1.2 2.9e-14 53.1 0.0 2.6 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 EPS29791.1 - 7.6e-12 44.7 0.0 1.6e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EPS29791.1 - 9.8e-11 41.3 0.0 1.9e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EPS29791.1 - 1.5e-10 40.6 0.0 3.1e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Rapsyn_N PF10579.9 EPS29791.1 - 0.041 14.0 0.1 0.087 12.9 0.1 1.5 1 0 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region DASH_Duo1 PF08651.10 EPS29792.1 - 9e-32 108.7 2.7 2e-31 107.6 2.7 1.6 1 0 0 1 1 1 1 DASH complex subunit Duo1 DASH_Dad2 PF08654.10 EPS29792.1 - 0.69 10.4 4.9 1.2 9.5 4.9 1.5 1 0 0 1 1 1 0 DASH complex subunit Dad2 DUF745 PF05335.13 EPS29792.1 - 1.1 8.9 8.9 2 8.1 8.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) zf-primase PF09329.11 EPS29794.1 - 5.6e-18 64.5 1.6 1.3e-17 63.3 1.6 1.7 1 0 0 1 1 1 1 Primase zinc finger RNase_H2-Ydr279 PF09468.10 EPS29795.1 - 9.3e-43 146.2 0.0 9.3e-43 146.2 0.0 1.9 2 0 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 EPS29795.1 - 5.2e-19 68.3 0.1 1.1e-18 67.2 0.1 1.6 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain GalKase_gal_bdg PF10509.9 EPS29796.1 - 8.2e-20 70.1 0.0 1.6e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 EPS29796.1 - 3.8e-15 55.9 1.4 9.4e-15 54.6 1.4 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EPS29796.1 - 1.6e-13 50.8 0.0 4e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal Sigma70_r3 PF04539.16 EPS29796.1 - 0.1 12.7 0.5 0.58 10.3 0.2 2.3 2 0 0 2 2 2 0 Sigma-70 region 3 PP2C_C PF07830.13 EPS29796.1 - 0.25 11.8 2.2 30 5.2 0.0 2.7 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain TPP_enzyme_N PF02776.18 EPS29798.1 - 1.5e-55 187.5 0.1 4e-53 179.5 0.0 2.7 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EPS29798.1 - 4.8e-48 162.8 0.1 9.7e-47 158.6 0.0 2.7 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EPS29798.1 - 2.1e-41 140.8 0.1 4.3e-41 139.9 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Vps35 PF03635.17 EPS29799.1 - 0 1029.4 1.7 0 1029.2 1.7 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 UPF0561 PF10573.9 EPS29799.1 - 0.23 11.6 1.2 0.5 10.5 1.2 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 Vfa1 PF08432.10 EPS29799.1 - 3.6 7.9 6.7 6.3 7.1 6.7 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 NST1 PF13945.6 EPS29801.1 - 4.9e-70 235.5 1.5 4.9e-70 235.5 1.5 4.4 2 2 2 4 4 4 1 Salt tolerance down-regulator Ras PF00071.22 EPS29803.1 - 5.3e-48 162.7 0.0 6.2e-48 162.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EPS29803.1 - 7.2e-22 77.9 0.0 1.3e-21 77.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPS29803.1 - 2.6e-07 30.3 0.0 3.4e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EPS29803.1 - 0.0033 16.9 0.0 0.0077 15.7 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EPS29803.1 - 0.011 15.2 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 EPS29803.1 - 0.097 12.4 0.0 2.6 7.8 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ADH_zinc_N PF00107.26 EPS29803.1 - 0.14 12.2 0.0 18 5.3 0.0 2.2 2 0 0 2 2 2 0 Zinc-binding dehydrogenase MMR_HSR1 PF01926.23 EPS29803.1 - 0.17 12.0 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_21 PF13304.6 EPS29803.1 - 0.23 11.3 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system MRP-L28 PF09812.9 EPS29804.1 - 1.6e-06 28.4 0.0 2.1e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Mfp-3 PF04202.13 EPS29804.1 - 0.061 13.7 0.6 0.52 10.7 0.1 2.1 2 0 0 2 2 2 0 Foot protein 3 DUF4337 PF14235.6 EPS29804.1 - 0.19 11.8 0.2 0.27 11.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) RINGv PF12906.7 EPS29805.1 - 1.6e-05 24.9 6.2 3.1e-05 24.0 6.2 1.5 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 EPS29805.1 - 6.6e-05 23.0 2.7 0.00013 22.1 2.7 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 EPS29805.1 - 0.057 13.8 5.1 0.14 12.6 5.1 1.7 1 0 0 1 1 1 0 Ring finger domain Transthyretin PF00576.21 EPS29806.1 - 2.9e-32 111.6 0.0 3.6e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 HIUase/Transthyretin family ArsA_ATPase PF02374.15 EPS29807.1 - 2e-115 385.2 0.0 2.2e-115 385.0 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 EPS29807.1 - 2.2e-13 50.5 0.3 1e-12 48.3 0.0 2.2 2 2 0 2 2 2 1 AAA domain CbiA PF01656.23 EPS29807.1 - 9.3e-13 48.4 0.0 1.4e-12 47.8 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 EPS29807.1 - 2.5e-06 27.2 0.0 5.4e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 EPS29807.1 - 1.9e-05 24.3 2.3 0.00012 21.6 0.1 2.4 3 0 0 3 3 3 1 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 EPS29807.1 - 4.4e-05 23.2 0.0 0.00083 19.0 0.1 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain CBP_BcsQ PF06564.12 EPS29807.1 - 9.4e-05 22.0 0.0 0.00024 20.6 0.0 1.6 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ PhoH PF02562.16 EPS29807.1 - 0.01 15.3 0.1 0.033 13.6 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein A1_Propeptide PF07966.12 EPS29807.1 - 0.069 13.0 0.0 0.37 10.7 0.0 2.4 1 0 0 1 1 1 0 A1 Propeptide AAA_25 PF13481.6 EPS29807.1 - 0.078 12.6 0.0 0.2 11.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain RecG_N PF17190.4 EPS29807.1 - 0.09 13.5 0.9 0.43 11.3 0.2 2.4 2 0 0 2 2 2 0 RecG N-terminal helical domain AAA_24 PF13479.6 EPS29807.1 - 0.13 12.0 0.1 0.84 9.3 0.1 2.2 1 1 0 1 1 1 0 AAA domain VirC1 PF07015.11 EPS29807.1 - 0.15 11.3 0.1 0.98 8.7 0.0 2.0 2 0 0 2 2 2 0 VirC1 protein ABC_tran_CTD PF16326.5 EPS29807.1 - 0.23 11.7 1.3 1.2 9.4 0.0 2.7 4 0 0 4 4 3 0 ABC transporter C-terminal domain Amidase PF01425.21 EPS29808.1 - 9.3e-53 179.8 0.4 1.6e-51 175.7 0.4 2.6 1 1 0 1 1 1 1 Amidase HMD PF03201.16 EPS29808.1 - 0.044 14.0 0.0 0.22 11.8 0.0 2.1 2 0 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase eIF3_N PF09440.10 EPS29810.1 - 1.6e-52 177.5 1.6 3.7e-52 176.3 1.6 1.7 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 EPS29810.1 - 1.5e-14 54.4 0.0 4.2e-14 52.9 0.0 1.8 1 0 0 1 1 1 1 PCI domain Img2 PF05046.14 EPS29811.1 - 7.7e-26 90.2 0.0 1.2e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SBP PF03110.14 EPS29811.1 - 0.0048 17.2 0.9 0.009 16.3 0.9 1.5 1 0 0 1 1 1 1 SBP domain Flavoprotein PF02441.19 EPS29812.1 - 3.5e-43 147.1 0.0 7.5e-43 146.0 0.0 1.5 1 1 0 1 1 1 1 Flavoprotein ARID PF01388.21 EPS29813.1 - 8.1e-21 74.5 0.1 4.8e-20 72.0 0.1 2.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain DUF4720 PF15846.5 EPS29813.1 - 0.027 14.3 0.1 0.072 12.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4720) AAA PF00004.29 EPS29814.1 - 3.3e-46 157.0 0.6 8.5e-46 155.7 0.0 2.0 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EPS29814.1 - 1.2e-10 41.2 0.1 7.6e-10 38.6 0.0 2.2 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 EPS29814.1 - 5.1e-09 36.5 0.0 1e-08 35.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EPS29814.1 - 7e-09 35.8 0.6 2.2e-08 34.2 0.1 2.1 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EPS29814.1 - 1e-07 32.5 0.3 2.5e-05 24.7 0.0 2.9 2 2 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EPS29814.1 - 2.2e-05 24.7 1.1 0.0055 17.0 0.1 2.7 1 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 EPS29814.1 - 6.5e-05 22.2 0.0 0.00013 21.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_lid_3 PF17862.1 EPS29814.1 - 0.00019 21.2 0.0 0.00045 20.0 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_14 PF13173.6 EPS29814.1 - 0.00021 21.3 0.0 0.00074 19.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 EPS29814.1 - 0.00027 20.9 0.0 0.021 14.8 0.0 2.3 1 1 1 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RuvB_N PF05496.12 EPS29814.1 - 0.00029 20.6 0.0 0.00087 19.1 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 EPS29814.1 - 0.00059 19.4 0.0 0.0067 16.0 0.1 2.4 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_18 PF13238.6 EPS29814.1 - 0.0011 19.5 0.0 0.0035 17.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain NTPase_1 PF03266.15 EPS29814.1 - 0.0013 18.7 0.0 0.0048 16.8 0.0 1.9 2 0 0 2 2 2 1 NTPase RNA_helicase PF00910.22 EPS29814.1 - 0.0015 18.9 0.0 0.0031 17.9 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 EPS29814.1 - 0.002 18.3 0.0 0.0045 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 EPS29814.1 - 0.0035 16.6 0.0 0.0069 15.6 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain NACHT PF05729.12 EPS29814.1 - 0.0045 16.9 0.3 0.11 12.4 0.0 2.9 3 0 0 3 3 3 1 NACHT domain AAA_3 PF07726.11 EPS29814.1 - 0.0047 16.8 0.0 0.014 15.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EPS29814.1 - 0.0074 16.5 0.0 0.018 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EPS29814.1 - 0.0077 15.6 0.0 0.018 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 EPS29814.1 - 0.0086 15.8 0.6 0.03 14.0 0.1 2.2 2 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 EPS29814.1 - 0.0095 15.7 0.1 0.23 11.1 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain TniB PF05621.11 EPS29814.1 - 0.011 15.2 0.0 0.54 9.6 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein AAA_24 PF13479.6 EPS29814.1 - 0.012 15.3 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EPS29814.1 - 0.012 15.3 0.0 0.051 13.3 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_11 PF13086.6 EPS29814.1 - 0.044 13.6 0.1 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 EPS29814.1 - 0.049 13.0 0.9 0.56 9.5 0.0 2.4 3 0 0 3 3 2 0 KaiC ATPase_2 PF01637.18 EPS29814.1 - 0.049 13.5 1.1 0.35 10.7 0.1 2.5 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea Bac_DnaA PF00308.18 EPS29814.1 - 0.067 13.0 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_25 PF13481.6 EPS29814.1 - 0.079 12.5 1.3 0.22 11.1 0.1 2.2 2 1 1 3 3 3 0 AAA domain Zeta_toxin PF06414.12 EPS29814.1 - 0.09 12.0 0.0 0.24 10.7 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.6 EPS29814.1 - 0.1 13.1 0.3 2.5 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EPS29814.1 - 0.13 12.0 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EPS29814.1 - 0.13 12.8 0.1 0.56 10.7 0.0 2.2 3 0 0 3 3 2 0 ABC transporter AAA_19 PF13245.6 EPS29814.1 - 0.14 12.5 0.1 0.4 11.0 0.1 1.7 1 0 0 1 1 1 0 AAA domain Viral_Hsp90 PF03225.14 EPS29814.1 - 0.17 10.4 0.0 0.27 9.7 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue Parvo_NS1 PF01057.17 EPS29814.1 - 0.2 10.7 0.0 0.37 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Ank_2 PF12796.7 EPS29815.1 - 3.7e-39 133.2 4.1 8.5e-13 48.7 0.4 5.2 2 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EPS29815.1 - 2.3e-34 117.0 10.3 9.5e-07 29.0 0.1 8.6 4 1 5 9 9 9 7 Ankyrin repeats (many copies) Ank_4 PF13637.6 EPS29815.1 - 2e-33 114.3 7.8 6e-06 26.7 0.1 8.4 5 2 4 9 9 8 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPS29815.1 - 5.9e-27 90.8 7.6 0.0051 17.2 0.0 10.2 10 0 0 10 10 10 5 Ankyrin repeat Ank PF00023.30 EPS29815.1 - 4.8e-22 77.4 14.2 0.0022 18.4 0.1 9.7 9 0 0 9 9 9 6 Ankyrin repeat NACHT PF05729.12 EPS29815.1 - 1.9e-07 31.1 0.1 3.7e-07 30.2 0.1 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EPS29815.1 - 1.8e-06 28.4 0.6 6.9e-06 26.5 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EPS29815.1 - 0.0007 19.9 0.0 0.0024 18.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EPS29815.1 - 0.0017 18.9 0.0 0.0067 17.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain Ploopntkinase3 PF18751.1 EPS29815.1 - 0.0087 16.0 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 P-loop Nucleotide Kinase3 RNA_helicase PF00910.22 EPS29815.1 - 0.0098 16.3 0.0 0.022 15.1 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_29 PF13555.6 EPS29815.1 - 0.014 15.1 0.0 0.039 13.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Med14 PF08638.11 EPS29815.1 - 0.031 13.7 0.0 0.06 12.8 0.0 1.4 1 0 0 1 1 1 0 Mediator complex subunit MED14 AAA_33 PF13671.6 EPS29815.1 - 0.055 13.6 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT_sigma PF17106.5 EPS29815.1 - 0.088 13.0 15.2 0.23 11.6 15.2 1.6 1 0 0 1 1 1 0 Sigma domain on NACHT-NTPases SesA PF17107.5 EPS29816.1 - 6.7e-42 142.5 0.0 8.6e-42 142.2 0.0 1.1 1 0 0 1 1 1 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NACHT_sigma PF17106.5 EPS29816.1 - 1.1e-14 54.3 16.4 1.6e-14 53.8 16.4 1.2 1 0 0 1 1 1 1 Sigma domain on NACHT-NTPases SLATT_4 PF18186.1 EPS29816.1 - 0.0017 18.0 0.0 0.0021 17.7 0.0 1.2 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain family 4 Helo_like_N PF17111.5 EPS29816.1 - 0.0082 15.5 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins DUF2802 PF10975.8 EPS29816.1 - 0.11 12.7 0.6 5.8 7.1 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2802) SesA PF17107.5 EPS29817.1 - 7.4e-33 113.3 0.6 1.1e-32 112.7 0.3 1.4 2 0 0 2 2 2 1 N-terminal domain on NACHT_NTPase and P-loop NTPases NACHT_sigma PF17106.5 EPS29817.1 - 9.6e-09 35.2 22.0 1.9e-08 34.3 22.0 1.5 2 0 0 2 2 2 1 Sigma domain on NACHT-NTPases Asp PF00026.23 EPS29818.1 - 2.7e-105 352.3 0.0 3.9e-105 351.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EPS29818.1 - 8.9e-16 58.6 2.4 2e-13 51.0 1.8 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EPS29818.1 - 1.4e-05 25.6 0.2 0.072 13.7 0.0 3.5 3 2 0 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.6 EPS29818.1 - 0.00011 22.7 0.0 0.2 12.2 0.0 2.9 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 EPS29818.1 - 0.0082 15.9 0.0 0.11 12.3 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal NIF PF03031.18 EPS29819.1 - 2.9e-27 95.4 0.0 6.5e-27 94.2 0.0 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.7 EPS29819.1 - 1.6e-07 31.1 0.3 3.6e-07 30.0 0.3 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 EPS29819.1 - 3.3e-07 30.6 0.0 7.5e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EPS29819.1 - 0.00029 21.2 0.1 0.0052 17.2 0.0 2.4 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EPS29819.1 - 0.032 14.5 0.1 0.073 13.4 0.1 1.6 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain RTT107_BRCT_5 PF16770.5 EPS29819.1 - 0.047 13.6 0.0 0.089 12.7 0.0 1.4 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 EPS29819.1 - 0.12 12.4 0.2 0.35 11.0 0.2 1.7 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain zf-C2H2_11 PF16622.5 EPS29820.1 - 0.034 13.9 0.8 0.056 13.2 0.8 1.3 1 0 0 1 1 1 0 zinc-finger C2H2-type Arginase PF00491.21 EPS29822.1 - 1.6e-77 260.7 0.5 1.9e-77 260.5 0.5 1.0 1 0 0 1 1 1 1 Arginase family GatB_N PF02934.15 EPS29823.1 - 3.2e-96 321.9 0.0 4.1e-96 321.6 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 EPS29823.1 - 8.1e-27 93.9 0.1 1.5e-26 93.1 0.1 1.4 1 0 0 1 1 1 1 GatB domain DUF1117 PF06547.12 EPS29825.1 - 0.33 11.5 1.3 0.75 10.4 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1117) IMUP PF15761.5 EPS29825.1 - 3.2 8.5 18.8 0.12 13.1 7.6 2.6 2 0 0 2 2 2 0 Immortalisation up-regulated protein COG4 PF08318.12 EPS29826.1 - 0.0023 17.1 0.2 0.008 15.3 0.2 1.9 1 0 0 1 1 1 1 COG4 transport protein ECH_1 PF00378.20 EPS29828.1 - 2.5e-38 131.8 0.0 5.8e-38 130.6 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EPS29828.1 - 5.1e-27 95.2 0.0 5.7e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase LmjF365940-deam PF14421.6 EPS29828.1 - 0.16 11.6 0.1 0.21 11.2 0.1 1.2 1 0 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases Abhydrolase_6 PF12697.7 EPS29829.1 - 2.5e-05 25.0 0.0 3.7e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 EPS29829.1 - 7.5e-05 22.3 0.2 0.00041 19.9 0.1 1.9 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Cutinase PF01083.22 EPS29829.1 - 0.0083 16.1 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 Cutinase PGAP1 PF07819.13 EPS29829.1 - 0.014 15.1 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.8 EPS29829.1 - 0.034 13.4 0.1 0.12 11.6 0.0 1.9 2 0 0 2 2 2 0 Serine aminopeptidase, S33 NB-ARC PF00931.22 EPS29830.1 - 4.9e-12 45.6 0.0 7.4e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 EPS29830.1 - 2.8e-05 24.6 0.0 6.3e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EPS29830.1 - 0.0003 21.1 0.0 0.0012 19.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 EPS29830.1 - 0.00052 19.4 0.0 0.00097 18.5 0.0 1.4 1 0 0 1 1 1 1 KaiC NACHT PF05729.12 EPS29830.1 - 0.00063 19.7 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Zeta_toxin PF06414.12 EPS29830.1 - 0.0026 17.1 0.0 0.0058 15.9 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 EPS29830.1 - 0.015 15.9 0.0 0.042 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EPS29830.1 - 0.02 15.0 0.0 0.048 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EPS29830.1 - 0.087 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EPS29830.1 - 0.1 12.3 0.0 0.28 10.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 EPS29830.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.26 EPS29830.1 - 0.19 11.4 0.0 0.32 10.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain adh_short PF00106.25 EPS29831.1 - 1.6e-06 27.7 0.0 2.3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPS29831.1 - 1e-05 25.5 0.0 1.6e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Zn_clus PF00172.18 EPS29832.1 - 0.00025 21.1 14.5 0.00025 21.1 14.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-MYST PF17772.1 EPS29832.1 - 0.044 13.4 1.5 0.068 12.8 0.7 1.8 2 0 0 2 2 2 0 MYST family zinc finger domain APH PF01636.23 EPS29835.1 - 1e-11 45.2 0.3 1.6e-11 44.6 0.3 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.11 EPS29835.1 - 0.00099 18.1 0.0 0.081 11.8 0.0 2.2 2 1 0 2 2 2 2 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 EPS29835.1 - 0.02 14.5 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 EPS29835.1 - 0.049 13.2 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 RIO1 family DUF883 PF05957.13 EPS29836.1 - 0.0013 19.2 9.7 0.003 18.1 5.5 2.1 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF883) YbjQ_1 PF01906.17 EPS29836.1 - 0.0098 16.5 1.9 0.015 15.9 1.5 1.6 1 1 0 1 1 1 1 Putative heavy-metal-binding CdvA PF18822.1 EPS29836.1 - 0.048 13.5 3.9 0.053 13.4 1.8 2.0 1 1 2 3 3 3 0 CdvA-like coiled-coil domain CtnDOT_TraJ PF07863.11 EPS29836.1 - 0.17 12.5 0.8 0.17 12.5 0.8 2.1 2 0 0 2 2 2 0 Homologues of TraJ from Bacteroides conjugative transposon CsbD PF05532.12 EPS29836.1 - 3.1 7.8 26.6 1.4 8.9 10.0 3.4 2 1 1 3 3 3 0 CsbD-like YtxH PF12732.7 EPS29836.1 - 3.8 8.1 13.9 4.8e+02 1.4 13.9 2.2 1 1 0 1 1 1 0 YtxH-like protein FHA PF00498.26 EPS29837.1 - 3.3e-14 53.0 0.5 7.5e-14 51.8 0.0 1.9 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 EPS29837.1 - 0.062 13.6 0.0 1.5 9.2 0.0 2.3 1 1 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain DnaJ PF00226.31 EPS29838.1 - 1.7e-09 37.6 0.4 1.7e-09 37.6 0.4 1.9 2 0 0 2 2 2 1 DnaJ domain Abhydrolase_3 PF07859.13 EPS29839.1 - 3.8e-43 147.8 0.1 6.9e-42 143.7 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EPS29839.1 - 1.3e-08 34.2 0.0 2.8e-08 33.0 0.0 1.5 1 1 0 1 1 1 1 Steryl acetyl hydrolase DUF3367 PF11847.8 EPS29840.1 - 2.4 5.9 5.3 0.22 9.4 0.4 1.6 2 0 0 2 2 2 0 Alpha-(1->3)-arabinofuranosyltransferase ATG11 PF10377.9 EPS29842.1 - 8.8e-46 155.1 0.1 8.8e-46 155.1 0.1 4.3 5 0 0 5 5 5 1 Autophagy-related protein 11 APG17 PF04108.12 EPS29842.1 - 3e-09 36.5 0.8 1.2e-06 28.0 1.0 5.3 3 2 1 4 4 4 2 Autophagy protein Apg17 DUF1664 PF07889.12 EPS29842.1 - 2.3 8.2 45.1 0.034 14.2 2.9 8.1 7 2 1 9 9 9 0 Protein of unknown function (DUF1664) Exonuc_VII_L PF02601.15 EPS29842.1 - 2.5 7.6 52.8 0.011 15.4 10.9 5.3 5 1 0 5 5 5 0 Exonuclease VII, large subunit CENP-H PF05837.12 EPS29843.1 - 5.8e-31 107.2 8.5 5.8e-31 107.2 8.5 2.1 2 0 0 2 2 2 2 Centromere protein H (CENP-H) NCD1 PF04904.13 EPS29843.1 - 0.016 15.2 0.6 4.7 7.3 0.1 2.6 1 1 1 2 2 2 0 NAB conserved region 1 (NCD1) DUF410 PF04190.13 EPS29843.1 - 0.033 14.0 0.4 0.033 14.0 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF410) PRKG1_interact PF15898.5 EPS29843.1 - 0.44 11.5 15.7 3 8.8 0.1 3.1 2 1 0 2 2 2 0 cGMP-dependent protein kinase interacting domain THP2 PF09432.10 EPS29843.1 - 1.5 8.9 14.1 0.17 11.9 1.7 3.0 1 1 1 3 3 3 0 Tho complex subunit THP2 HMG_box PF00505.19 EPS29845.1 - 1.2e-25 89.7 2.0 1.2e-25 89.7 2.0 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EPS29845.1 - 9.1e-18 64.6 3.0 9.1e-18 64.6 3.0 1.6 2 0 0 2 2 2 1 HMG-box domain Ccdc124 PF06244.12 EPS29845.1 - 0.00085 19.9 0.0 0.00085 19.9 0.0 2.1 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 CHDNT PF08073.12 EPS29845.1 - 0.015 15.3 0.0 0.023 14.6 0.0 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain Homoserine_dh PF00742.19 EPS29849.1 - 2.5e-52 177.3 0.0 3.5e-52 176.8 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 EPS29849.1 - 1.1e-15 58.4 0.0 2e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF4078 PF13300.6 EPS29850.1 - 1.9e-24 85.8 12.9 1.9e-24 85.8 12.9 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4078) ARGLU PF15346.6 EPS29850.1 - 1.3 8.9 17.5 0.1 12.5 11.8 2.0 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 RSN1_7TM PF02714.15 EPS29851.1 - 2.2e-80 269.9 22.3 2.2e-80 269.9 22.3 1.7 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EPS29851.1 - 1.7e-40 138.4 1.3 1.7e-40 138.4 1.3 2.5 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EPS29851.1 - 1.4e-37 129.6 0.0 2.1e-37 129.1 0.0 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter F_bP_aldolase PF01116.20 EPS29852.1 - 3.9e-92 308.7 0.0 4.4e-92 308.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II UCH PF00443.29 EPS29854.1 - 6e-39 134.1 0.0 7.3e-34 117.4 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EPS29854.1 - 2.6e-10 40.4 0.5 1.5e-08 34.6 0.5 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase AlaDh_PNT_N PF05222.15 EPS29855.1 - 6.3e-29 101.0 0.0 1e-28 100.3 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 EPS29855.1 - 0.00087 18.6 0.0 0.011 15.1 0.0 2.3 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FancD2 PF14631.6 EPS29856.1 - 9.4 3.5 6.7 13 3.0 6.7 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease CUE PF02845.16 EPS29858.1 - 9.1e-12 44.4 0.0 1.4e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 CUE domain PRP38_assoc PF12871.7 EPS29858.1 - 4.8 7.9 13.5 0.14 12.8 1.0 3.7 3 0 0 3 3 3 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Oxysterol_BP PF01237.18 EPS29859.1 - 6.4e-61 206.2 6.1 2.8e-54 184.4 0.1 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein MFS_1 PF07690.16 EPS29860.1 - 1.8e-42 145.5 35.0 1.8e-42 145.5 35.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS29860.1 - 9.2e-09 34.7 8.8 9.2e-09 34.7 8.8 2.6 2 1 0 3 3 3 1 Sugar (and other) transporter OATP PF03137.20 EPS29860.1 - 0.15 10.3 4.4 0.084 11.1 1.5 2.1 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family ATG22 PF11700.8 EPS29861.1 - 2.3e-117 392.6 20.9 2.7e-117 392.4 20.9 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 EPS29861.1 - 6.5e-10 38.5 10.3 6.5e-10 38.5 10.3 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_1 PF07690.16 EPS29862.1 - 1.1e-38 133.1 59.6 2.4e-38 132.0 56.5 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EPS29862.1 - 2.7e-10 39.3 32.4 1e-09 37.4 32.4 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_3 PF00933.21 EPS29863.1 - 2.1e-84 283.6 0.0 2.7e-84 283.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.25 EPS29863.1 - 7.3e-14 52.0 0.0 7e-06 26.3 0.0 2.8 3 0 0 3 3 3 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EPS29863.1 - 6.9e-11 42.2 0.0 1.7e-07 31.2 0.0 2.6 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EPS29863.1 - 1.3e-10 41.5 0.0 0.00032 21.1 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Glyco_hydro_3_C PF01915.22 EPS29863.1 - 0.0046 16.9 0.0 0.011 15.8 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_9 PF13527.7 EPS29863.1 - 0.012 15.7 0.0 0.097 12.8 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Antibiotic_NAT PF02522.14 EPS29863.1 - 0.17 11.7 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Aminoglycoside 3-N-acetyltransferase MiaE_2 PF13794.6 EPS29864.1 - 0.049 13.3 0.0 0.071 12.8 0.0 1.2 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like GST_N PF02798.20 EPS29865.1 - 5.2e-16 58.7 0.0 1.3e-15 57.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EPS29865.1 - 7.8e-15 55.0 0.0 1.4e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EPS29865.1 - 4.2e-14 52.5 0.0 6.7e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EPS29865.1 - 3.4e-10 40.1 0.0 6.3e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EPS29865.1 - 4.1e-10 39.7 0.0 8.4e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EPS29865.1 - 1.8e-06 27.9 0.0 4.7e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EPS29865.1 - 0.043 13.6 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain RNase_T PF00929.24 EPS29867.1 - 1.8e-28 100.2 0.0 2e-28 100.0 0.0 1.0 1 0 0 1 1 1 1 Exonuclease PGM_PMM_I PF02878.16 EPS29868.1 - 6e-32 110.2 0.0 8.9e-32 109.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EPS29868.1 - 1.2e-26 93.1 0.0 2.4e-26 92.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EPS29868.1 - 5e-17 62.4 0.1 1e-16 61.4 0.1 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EPS29868.1 - 1.4e-07 31.6 0.0 3.4e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain GFO_IDH_MocA PF01408.22 EPS29869.1 - 4.7e-12 46.8 0.4 5.7e-11 43.3 0.4 2.3 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EPS29869.1 - 0.001 19.0 0.0 0.0023 17.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Whib PF02467.16 EPS29869.1 - 0.073 13.7 0.1 0.22 12.1 0.1 1.8 1 0 0 1 1 1 0 Transcription factor WhiB Sugar_tr PF00083.24 EPS29870.1 - 3.3e-83 280.1 27.1 4.1e-83 279.7 27.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS29870.1 - 4.5e-28 98.2 45.0 1.9e-22 79.7 17.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EPS29870.1 - 0.0046 15.9 7.1 0.0046 15.9 7.1 2.3 2 1 1 3 3 3 1 MFS_1 like family CRM1_repeat_3 PF18787.1 EPS29870.1 - 0.053 13.6 0.2 0.15 12.2 0.2 1.7 1 0 0 1 1 1 0 CRM1 / Exportin repeat 3 PsbJ PF01788.17 EPS29870.1 - 0.16 11.9 1.7 0.89 9.5 0.1 2.9 2 0 0 2 2 2 0 PsbJ DUF4212 PF13937.6 EPS29870.1 - 1.3 9.5 12.9 0.42 11.0 2.5 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4212) K_oxygenase PF13434.6 EPS29871.1 - 3.9e-14 52.6 0.0 2.6e-08 33.4 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EPS29871.1 - 4.7e-05 23.1 0.5 0.55 9.8 0.0 3.8 3 1 0 4 4 4 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EPS29871.1 - 8.2e-05 22.0 0.2 0.028 13.7 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EPS29871.1 - 8.7e-05 21.9 0.1 0.4 9.8 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EPS29871.1 - 0.0012 18.9 0.0 0.45 10.5 0.0 3.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 EPS29871.1 - 0.0029 16.9 0.1 0.025 13.9 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 EPS29871.1 - 0.0065 15.6 0.2 0.017 14.2 0.1 1.7 1 1 0 1 1 1 1 Lycopene cyclase protein Shikimate_DH PF01488.20 EPS29871.1 - 0.01 15.9 0.1 0.4 10.8 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 EPS29871.1 - 0.018 14.1 0.0 0.043 12.9 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 EPS29871.1 - 0.022 13.5 0.1 0.11 11.1 0.0 2.1 3 0 0 3 3 3 0 HI0933-like protein FAD_binding_3 PF01494.19 EPS29871.1 - 0.043 13.0 0.2 0.16 11.2 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.6 EPS29871.1 - 0.072 13.3 0.2 0.75 10.1 0.0 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Malic_M PF03949.15 EPS29871.1 - 0.085 12.1 0.4 2.2 7.5 0.0 2.7 3 0 0 3 3 3 0 Malic enzyme, NAD binding domain HMG_CoA_synt_C PF08540.10 EPS29873.1 - 4.2e-106 354.6 1.3 5.4e-106 354.3 1.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 EPS29873.1 - 1.8e-97 324.2 0.1 2.7e-97 323.7 0.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Ribosomal_L22e PF01776.17 EPS29875.1 - 2.9e-47 159.5 0.4 3.6e-47 159.2 0.4 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF676 PF05057.14 EPS29877.1 - 6e-50 169.8 0.0 8.9e-50 169.2 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 EPS29877.1 - 3.2e-06 27.1 0.0 1.5e-05 24.9 0.0 1.9 1 1 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 EPS29877.1 - 3.6e-05 23.7 0.0 5.8e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.7 EPS29877.1 - 0.0006 20.5 0.0 0.0017 19.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.15 EPS29877.1 - 0.0072 15.5 0.0 0.0093 15.2 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase PE-PPE PF08237.11 EPS29877.1 - 0.066 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain DUF915 PF06028.11 EPS29877.1 - 0.12 11.7 0.0 0.57 9.5 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_2 PF01674.18 EPS29877.1 - 0.12 11.9 0.1 0.34 10.4 0.1 1.7 1 1 0 1 1 1 0 Lipase (class 2) tRNA_SAD PF07973.14 EPS29878.1 - 2.3e-10 40.4 0.3 4.2e-10 39.6 0.3 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 EPS29878.1 - 5.1e-10 38.5 0.0 6.2e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) Hydrolase_6 PF13344.6 EPS29879.1 - 4.1e-22 78.2 0.0 7.4e-22 77.4 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EPS29879.1 - 1.9e-10 40.7 0.0 1.4e-09 37.9 0.0 2.3 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 EPS29879.1 - 0.017 15.4 0.0 7.6 6.8 0.0 2.8 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Lipase_3 PF01764.25 EPS29879.1 - 0.18 11.6 0.0 0.53 10.1 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) CFEM PF05730.11 EPS29880.1 - 0.00031 20.8 4.8 0.00059 19.9 4.8 1.4 1 0 0 1 1 1 1 CFEM domain Mid2 PF04478.12 EPS29880.1 - 0.0096 15.8 0.4 0.021 14.7 0.4 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor TMEM154 PF15102.6 EPS29880.1 - 0.47 10.4 9.1 3.2 7.6 9.1 2.1 1 1 0 1 1 1 0 TMEM154 protein family Pmp3 PF01679.17 EPS29881.1 - 2.1e-24 85.4 8.1 2.4e-24 85.3 8.1 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator ATP-synt_C PF00137.21 EPS29883.1 - 8.2e-36 122.2 33.2 4.5e-22 78.2 15.3 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF1713 PF08213.11 EPS29884.1 - 3.6e-10 39.6 22.1 7.1e-10 38.6 22.1 1.5 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.10 EPS29884.1 - 0.099 13.4 0.6 0.28 11.9 0.0 2.1 2 1 1 3 3 3 0 Mitochondrial protein Pet20 G-alpha PF00503.20 EPS29885.1 - 1.9e-106 356.3 0.1 2.2e-106 356.0 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EPS29885.1 - 5.2e-14 52.1 0.1 3.7e-09 36.3 0.0 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EPS29885.1 - 9.1e-08 31.7 0.2 7.6e-05 22.2 0.1 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 EPS29885.1 - 0.004 17.4 0.1 1.2 9.4 0.0 2.7 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EPS29885.1 - 0.0081 16.2 0.0 3.6 7.7 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 EPS29885.1 - 0.018 14.4 0.0 0.15 11.4 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family GTP_EFTU PF00009.27 EPS29885.1 - 0.059 12.9 0.0 0.94 9.0 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 EPS29885.1 - 0.061 13.1 0.2 0.13 12.0 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EPS29885.1 - 0.12 12.7 0.0 0.28 11.6 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain Peptidase_M13_N PF05649.13 EPS29887.1 - 7.7e-92 308.9 0.0 1.2e-91 308.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.21 EPS29887.1 - 1.4e-61 207.7 0.0 2.2e-61 207.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 RasGEF PF00617.19 EPS29889.1 - 9.4e-45 153.0 0.5 1.7e-44 152.1 0.5 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EPS29889.1 - 9.6e-13 48.3 0.2 2.2e-12 47.1 0.2 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif DIL PF01843.19 EPS29890.1 - 6.8e-31 106.6 1.3 1.4e-30 105.6 1.3 1.6 1 0 0 1 1 1 1 DIL domain Ank_2 PF12796.7 EPS29890.1 - 6.5e-15 55.5 0.0 3e-14 53.4 0.0 2.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EPS29890.1 - 1.2e-11 44.6 0.0 9.3e-06 25.8 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EPS29890.1 - 9.7e-10 38.8 0.1 0.0017 18.9 0.0 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EPS29890.1 - 3.1e-09 36.9 0.1 0.0089 16.4 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 EPS29890.1 - 7.3e-07 29.0 1.8 0.0094 16.4 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat SDA1 PF05285.12 EPS29892.1 - 0.93 8.9 18.6 1.8 7.9 17.2 1.9 2 0 0 2 2 2 0 SDA1 MFS_1 PF07690.16 EPS29893.1 - 4.8e-36 124.4 30.3 6.2e-36 124.0 30.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily YesK PF14150.6 EPS29893.1 - 1.9 8.7 11.2 0.18 12.0 1.7 3.5 4 0 0 4 4 4 0 YesK-like protein MFS_1_like PF12832.7 EPS29893.1 - 8.5 5.1 14.3 0.048 12.5 1.1 2.8 3 0 0 3 3 3 0 MFS_1 like family 3HCDH_N PF02737.18 EPS29894.1 - 1.2e-33 116.5 0.0 2.1e-33 115.7 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EPS29894.1 - 3.9e-14 53.0 0.0 8.4e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EPS29894.1 - 7.6e-06 26.2 0.1 1.6e-05 25.2 0.1 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 EPS29894.1 - 8.6e-06 26.2 0.3 2.9e-05 24.6 0.3 1.9 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 EPS29894.1 - 0.00073 19.5 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.19 EPS29894.1 - 0.0038 16.6 0.0 0.0079 15.6 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 EPS29894.1 - 0.0071 16.0 0.0 0.015 14.9 0.0 1.5 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 EPS29894.1 - 0.038 13.2 0.0 0.049 12.9 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EPS29894.1 - 0.042 14.3 0.0 0.08 13.4 0.0 1.5 1 1 0 1 1 1 0 Putative NAD(P)-binding PglD_N PF17836.1 EPS29894.1 - 0.049 14.3 0.0 0.1 13.3 0.0 1.5 1 0 0 1 1 1 0 PglD N-terminal domain Shikimate_DH PF01488.20 EPS29894.1 - 0.07 13.2 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.25 EPS29894.1 - 0.087 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase IlvN PF07991.12 EPS29894.1 - 0.14 11.8 0.0 0.39 10.3 0.0 1.7 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain RabGAP-TBC PF00566.18 EPS29895.1 - 2.5e-34 118.8 0.0 3.9e-34 118.2 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Mo25 PF08569.11 EPS29896.1 - 6.1e-133 443.2 0.4 6.9e-133 443.0 0.4 1.0 1 0 0 1 1 1 1 Mo25-like Methyltransf_25 PF13649.6 EPS29897.1 - 2.8e-11 43.9 0.0 9.2e-11 42.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS29897.1 - 2.1e-09 37.9 0.0 5.4e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPS29897.1 - 6.8e-09 35.7 0.0 1.5e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EPS29897.1 - 6e-08 32.4 0.1 1.3e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 EPS29897.1 - 1.2e-05 25.2 0.0 2.5e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EPS29897.1 - 5.5e-05 23.1 0.1 0.00012 22.1 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EPS29897.1 - 8.6e-05 22.1 0.1 0.00016 21.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.14 EPS29897.1 - 0.001 18.5 0.1 0.0018 17.7 0.1 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_9 PF08003.11 EPS29897.1 - 0.0034 16.4 0.0 0.0052 15.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.12 EPS29897.1 - 0.0098 16.6 0.0 0.031 15.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EPS29897.1 - 0.02 14.2 0.0 0.042 13.1 0.0 1.5 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase PCMT PF01135.19 EPS29897.1 - 0.022 14.5 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 EPS29897.1 - 0.027 15.5 0.0 0.074 14.1 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain RasGAP_C PF03836.15 EPS29897.1 - 0.06 13.5 0.3 0.15 12.2 0.3 1.6 1 0 0 1 1 1 0 RasGAP C-terminus Ubie_methyltran PF01209.18 EPS29897.1 - 0.062 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 EPS29897.1 - 0.078 12.3 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase domain CLZ PF16526.5 EPS29897.1 - 0.12 12.7 2.4 0.29 11.5 2.4 1.7 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Methyltransf_32 PF13679.6 EPS29897.1 - 0.18 11.8 0.5 1.8 8.6 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Cir_N PF10197.9 EPS29898.1 - 5.6e-06 26.4 4.0 5.6e-06 26.4 4.0 4.2 4 1 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR YaiA PF16362.5 EPS29898.1 - 2.9 8.1 6.8 0.76 9.9 1.7 2.3 2 0 0 2 2 2 0 YaiA protein AAA PF00004.29 EPS29899.1 - 1e-53 181.3 0.0 1e-38 132.8 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EPS29899.1 - 3e-11 43.0 0.2 1e-10 41.2 0.0 2.0 2 0 0 2 2 1 1 AAA+ lid domain AAA_22 PF13401.6 EPS29899.1 - 2e-10 41.1 0.0 0.00023 21.5 0.0 3.8 3 1 0 3 3 3 2 AAA domain CDC48_2 PF02933.17 EPS29899.1 - 2e-10 40.3 0.3 5.5e-09 35.7 0.1 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_16 PF13191.6 EPS29899.1 - 8.4e-09 36.0 0.3 0.0061 16.9 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 EPS29899.1 - 1.9e-08 34.4 0.0 0.0013 18.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EPS29899.1 - 4.7e-08 32.7 0.1 0.0045 16.4 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EPS29899.1 - 2.4e-07 31.0 0.0 0.0043 17.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.14 EPS29899.1 - 4.3e-07 30.2 0.0 0.00013 22.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EPS29899.1 - 6.2e-07 29.3 0.1 0.056 13.2 0.0 2.9 2 1 1 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EPS29899.1 - 1.7e-06 27.5 0.0 0.026 13.8 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_18 PF13238.6 EPS29899.1 - 2.1e-06 28.3 0.0 0.091 13.3 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_24 PF13479.6 EPS29899.1 - 2.9e-06 27.1 0.0 0.018 14.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 EPS29899.1 - 5.8e-06 26.4 0.0 0.13 12.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EPS29899.1 - 1.9e-05 25.0 0.0 0.066 13.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase CDC48_N PF02359.18 EPS29899.1 - 2.6e-05 24.3 0.0 5.8e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_7 PF12775.7 EPS29899.1 - 5.7e-05 22.7 0.1 0.044 13.3 0.0 3.1 4 0 0 4 4 3 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 EPS29899.1 - 6.8e-05 22.7 0.0 0.19 11.4 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein TsaE PF02367.17 EPS29899.1 - 0.00019 21.4 0.0 0.43 10.6 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 EPS29899.1 - 0.0002 21.4 0.8 17 5.2 0.0 4.1 3 1 1 4 4 4 0 ATPase domain predominantly from Archaea ATPase PF06745.13 EPS29899.1 - 0.00028 20.3 0.1 0.076 12.3 0.1 2.4 2 0 0 2 2 2 1 KaiC NACHT PF05729.12 EPS29899.1 - 0.0003 20.8 0.2 0.18 11.7 0.0 2.7 3 0 0 3 3 2 1 NACHT domain AAA_25 PF13481.6 EPS29899.1 - 0.00053 19.6 0.2 0.87 9.1 0.0 2.8 2 1 0 2 2 2 2 AAA domain ABC_tran PF00005.27 EPS29899.1 - 0.00065 20.2 0.2 0.057 13.9 0.1 2.6 2 0 0 2 2 2 1 ABC transporter AAA_28 PF13521.6 EPS29899.1 - 0.00072 19.8 0.0 1.5 9.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.6 EPS29899.1 - 0.00082 19.2 0.0 0.68 9.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 EPS29899.1 - 0.00083 18.9 0.2 0.83 9.1 0.1 2.3 2 0 0 2 2 2 2 PhoH-like protein NB-ARC PF00931.22 EPS29899.1 - 0.0011 18.3 0.2 1.5 7.9 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain Sigma54_activat PF00158.26 EPS29899.1 - 0.0012 18.6 0.0 1.2 8.8 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_17 PF13207.6 EPS29899.1 - 0.0017 18.8 0.1 0.88 10.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EPS29899.1 - 0.0017 18.7 0.2 0.75 10.1 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_3 PF07726.11 EPS29899.1 - 0.0019 18.1 0.0 0.52 10.2 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EPS29899.1 - 0.0042 16.8 0.1 0.71 9.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 EPS29899.1 - 0.0099 15.2 0.1 1.8 7.8 0.1 2.4 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Parvo_NS1 PF01057.17 EPS29899.1 - 0.024 13.7 0.0 0.94 8.5 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 AAA_29 PF13555.6 EPS29899.1 - 0.035 13.8 0.3 3.6 7.4 0.0 2.8 2 1 0 2 2 2 0 P-loop containing region of AAA domain TniB PF05621.11 EPS29899.1 - 0.042 13.3 0.0 4 6.8 0.0 3.0 2 1 1 3 3 3 0 Bacterial TniB protein Rad17 PF03215.15 EPS29899.1 - 0.048 13.6 0.0 2 8.3 0.0 2.8 3 0 0 3 3 2 0 Rad17 P-loop domain ResIII PF04851.15 EPS29899.1 - 0.059 13.4 0.0 3.5 7.6 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit KTI12 PF08433.10 EPS29899.1 - 0.15 11.5 0.1 6.2 6.2 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Sigma54_activ_2 PF14532.6 EPS29899.1 - 0.16 12.1 0.0 29 4.8 0.0 3.1 4 0 0 4 4 3 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 EPS29899.1 - 0.17 11.1 0.1 5.4 6.2 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin KxDL PF10241.9 EPS29900.1 - 2e-32 111.3 0.3 2.6e-32 110.9 0.3 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein DAZAP2 PF11029.8 EPS29902.1 - 0.2 12.6 1.1 0.36 11.8 0.1 1.8 2 0 0 2 2 2 0 DAZ associated protein 2 (DAZAP2) HATPase_c PF02518.26 EPS29904.1 - 4.3e-22 78.7 0.8 1.1e-21 77.4 0.2 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EPS29904.1 - 3.3e-21 75.5 0.2 1.2e-20 73.7 0.1 2.0 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 EPS29904.1 - 1.5e-16 60.2 0.1 5.2e-16 58.4 0.1 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 EPS29904.1 - 1.9e-12 47.3 0.7 0.00049 20.3 0.1 4.0 3 1 1 4 4 4 3 PAS fold PAS_4 PF08448.10 EPS29904.1 - 8.4e-09 35.7 0.1 1.5e-06 28.5 0.0 3.3 3 0 0 3 3 3 1 PAS fold PAS PF00989.25 EPS29904.1 - 3.2e-06 27.1 0.0 0.043 13.8 0.0 2.9 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 EPS29904.1 - 1.2e-05 25.5 0.0 0.2 11.9 0.0 3.5 3 1 0 3 3 3 2 PAS domain Ins_allergen_rp PF06757.13 EPS29904.1 - 0.08 12.9 0.5 12 5.8 0.0 2.9 3 0 0 3 3 3 0 Insect allergen related repeat, nitrile-specifier detoxification MotA_ExbB PF01618.16 EPS29904.1 - 0.099 12.4 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 MotA/TolQ/ExbB proton channel family HATPase_c PF02518.26 EPS29906.1 - 1.7e-30 105.8 0.0 5.2e-30 104.2 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EPS29906.1 - 4.1e-20 72.0 0.0 1.3e-19 70.4 0.0 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EPS29906.1 - 6.8e-19 67.7 0.0 2.3e-18 66.0 0.0 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 EPS29906.1 - 4.7e-12 46.4 0.0 1.3e-11 44.9 0.0 1.9 1 0 0 1 1 1 1 GAF domain AAA_16 PF13191.6 EPS29906.1 - 4.8e-10 40.1 0.0 1.9e-09 38.1 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain GAF PF01590.26 EPS29906.1 - 6.6e-07 30.0 0.0 1.5e-06 28.9 0.0 1.6 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 EPS29906.1 - 1.8e-05 25.1 0.0 4.3e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 GAF domain NB-ARC PF00931.22 EPS29906.1 - 2.8e-05 23.4 0.1 0.004 16.4 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain Pkinase PF00069.25 EPS29906.1 - 3.3e-05 23.4 0.0 0.00023 20.6 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain HATPase_c_3 PF13589.6 EPS29906.1 - 0.0029 17.4 0.0 0.0061 16.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_16 PF13432.6 EPS29906.1 - 0.0078 16.8 0.5 0.99 10.1 0.0 3.6 2 1 1 3 3 3 1 Tetratricopeptide repeat DUF2514 PF10721.9 EPS29906.1 - 0.011 15.8 0.3 0.023 14.7 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) ComR_TPR PF18710.1 EPS29906.1 - 0.099 12.2 0.5 9.9 5.6 0.2 2.7 2 0 0 2 2 2 0 ComR tetratricopeptide TPR_8 PF13181.6 EPS29906.1 - 0.13 12.5 0.3 5.7 7.4 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Sugar_tr PF00083.24 EPS29907.1 - 2.2e-62 211.4 29.6 2.6e-62 211.2 29.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS29907.1 - 5.3e-25 88.1 29.0 7.4e-25 87.6 29.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hyd_65N_2 PF14498.6 EPS29908.1 - 3.4e-62 210.4 0.0 4.9e-62 209.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_1 PF00232.18 EPS29909.1 - 3.9e-143 477.1 0.7 4.7e-143 476.9 0.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Cytochrom_B561 PF03188.16 EPS29911.1 - 2.7e-17 63.2 5.4 2.7e-17 63.2 5.4 1.7 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 YqhR PF11085.8 EPS29911.1 - 0.022 14.7 0.6 0.022 14.7 0.6 1.8 2 1 0 2 2 2 0 Conserved membrane protein YqhR DUF3784 PF12650.7 EPS29911.1 - 0.16 12.2 7.6 0.25 11.6 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3784) DUF4271 PF14093.6 EPS29911.1 - 0.72 9.7 7.4 0.25 11.3 4.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4271) SHP PF03579.13 EPS29911.1 - 1.1 9.3 4.3 3.5 7.6 0.6 2.4 1 1 1 2 2 2 0 Small hydrophobic protein DUF4079 PF13301.6 EPS29911.1 - 1.3 9.1 18.0 10 6.3 8.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) DUF202 PF02656.15 EPS29911.1 - 6.9 7.2 16.4 1.9 9.0 3.6 3.8 3 2 0 3 3 3 0 Domain of unknown function (DUF202) tRNA-synt_2b PF00587.25 EPS29912.1 - 2.9e-18 66.5 0.0 6.2e-18 65.4 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EPS29912.1 - 3.8e-08 33.5 6.3 4e-07 30.2 6.3 2.1 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain PRKG1_interact PF15898.5 EPS29912.1 - 0.0037 18.1 4.0 0.0037 18.1 4.0 1.8 2 0 0 2 2 1 1 cGMP-dependent protein kinase interacting domain BLOC1_2 PF10046.9 EPS29912.1 - 0.02 15.2 0.5 0.02 15.2 0.5 2.2 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SOGA PF11365.8 EPS29912.1 - 0.055 14.6 1.2 0.37 12.0 0.1 2.3 2 0 0 2 2 2 0 Protein SOGA CENP-F_leu_zip PF10473.9 EPS29912.1 - 0.097 12.7 8.7 2 8.5 2.1 2.3 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Uso1_p115_C PF04871.13 EPS29912.1 - 0.16 12.3 7.2 0.36 11.2 7.2 1.5 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region JIP_LZII PF16471.5 EPS29912.1 - 0.49 10.6 3.6 12 6.2 0.4 2.4 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II FapA PF03961.13 EPS29912.1 - 0.53 8.8 3.1 0.77 8.3 3.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Exonuc_VII_L PF02601.15 EPS29912.1 - 0.92 9.0 6.0 1.5 8.4 6.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Csm1_N PF18504.1 EPS29912.1 - 1.3 9.4 8.0 0.24 11.7 1.2 2.8 2 1 1 3 3 3 0 Csm1 N-terminal domain TPR_MLP1_2 PF07926.12 EPS29912.1 - 1.5 8.9 11.0 2.3 8.3 10.3 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.8 EPS29912.1 - 2.5 8.1 7.2 0.32 11.0 2.1 2.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Jnk-SapK_ap_N PF09744.9 EPS29912.1 - 3.8 7.7 9.0 3 8.1 2.4 1.9 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 ATG16 PF08614.11 EPS29912.1 - 7.2 6.8 18.5 1e+02 3.1 18.4 2.2 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Bromodomain PF00439.25 EPS29913.1 - 1.7e-17 63.3 0.1 6e-17 61.5 0.1 2.0 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 EPS29913.1 - 9.2e-10 38.4 0.0 2.7e-09 36.9 0.0 1.8 1 0 0 1 1 1 1 Bromodomain associated Bromo_TP_like PF17027.5 EPS29913.1 - 0.0037 17.4 0.0 0.0082 16.3 0.0 1.6 1 0 0 1 1 1 1 Histone-fold protein Inhibitor_I53 PF11714.8 EPS29913.1 - 6.3 7.1 8.4 0.78 10.0 3.7 2.0 2 0 0 2 2 2 0 Thrombin inhibitor Madanin VanZ PF04892.12 EPS29914.1 - 5.8e-07 30.2 1.1 1.1e-06 29.3 1.1 1.4 1 1 0 1 1 1 1 VanZ like family TrkH PF02386.16 EPS29914.1 - 0.055 11.9 0.1 0.51 8.7 0.0 2.0 2 0 0 2 2 2 0 Cation transport protein DUF4131 PF13567.6 EPS29914.1 - 10 5.8 6.6 29 4.3 4.4 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Y_phosphatase PF00102.27 EPS29915.1 - 4.1e-50 170.6 0.0 1.5e-49 168.7 0.0 1.8 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EPS29915.1 - 0.0093 16.0 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 EPS29915.1 - 0.015 15.5 0.0 0.041 14.0 0.0 1.7 2 0 0 2 2 2 0 Inositol hexakisphosphate DSPc PF00782.20 EPS29915.1 - 0.029 14.2 2.1 0.28 11.0 2.2 2.2 1 1 1 2 2 2 0 Dual specificity phosphatase, catalytic domain BTB PF00651.31 EPS29916.1 - 0.026 14.8 0.0 0.1 12.8 0.0 1.9 2 0 0 2 2 2 0 BTB/POZ domain Piwi PF02171.17 EPS29917.1 - 6.2e-67 226.0 0.0 1e-66 225.3 0.0 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 EPS29917.1 - 2e-11 43.8 0.0 4.2e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 EPS29917.1 - 1e-07 31.5 0.0 3e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoMid PF16487.5 EPS29917.1 - 3e-07 30.6 0.0 9.1e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 Mid domain of argonaute ArgoL2 PF16488.5 EPS29917.1 - 7.1e-07 29.5 0.0 1.6e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 2 domain Suf PF05843.14 EPS29918.1 - 3.7e-94 316.0 0.0 3.7e-94 316.0 0.0 4.3 5 1 0 5 5 5 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 EPS29918.1 - 0.00024 21.7 2.8 0.35 11.8 0.5 4.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EPS29918.1 - 0.002 18.8 0.3 0.016 15.9 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat ASF1_hist_chap PF04729.13 EPS29919.1 - 1.6e-72 242.5 0.0 2.3e-72 242.0 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Nop14 PF04147.12 EPS29919.1 - 0.0085 14.4 26.0 0.012 13.9 26.0 1.0 1 0 0 1 1 1 1 Nop14-like family Lgl_C PF08596.10 EPS29920.1 - 6e-133 443.3 0.0 1.9e-132 441.7 0.0 1.7 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 EPS29920.1 - 2.6e-06 27.7 0.0 0.73 10.2 0.0 5.1 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EPS29920.1 - 4.5e-06 27.3 2.3 0.75 10.8 0.0 5.2 7 0 0 7 7 7 2 WD domain, G-beta repeat APH PF01636.23 EPS29921.1 - 1.2e-07 31.9 0.0 2.1e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family THUMP PF02926.17 EPS29922.1 - 1.9e-14 53.9 0.3 3.1e-14 53.3 0.3 1.3 1 0 0 1 1 1 1 THUMP domain Cwf_Cwc_15 PF04889.12 EPS29922.1 - 0.043 13.5 2.7 0.067 12.9 2.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TPP_enzyme_N PF02776.18 EPS29923.1 - 2.8e-34 118.2 0.0 5.2e-34 117.3 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EPS29923.1 - 1.3e-21 76.8 0.0 2.9e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EPS29923.1 - 3.1e-16 59.5 0.0 6.2e-16 58.5 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 EPS29923.1 - 0.0029 16.6 0.0 0.0053 15.7 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Pkinase PF00069.25 EPS29924.1 - 3.5e-62 210.2 0.0 4.9e-62 209.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS29924.1 - 6e-44 150.3 0.0 8.8e-44 149.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EPS29924.1 - 3.8e-09 36.3 0.0 1.1e-06 28.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EPS29924.1 - 0.0019 17.0 0.0 0.004 16.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EPS29924.1 - 0.0094 15.3 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EPS29924.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sec34 PF04136.15 EPS29925.1 - 5.1e-50 169.2 0.5 1e-49 168.2 0.5 1.5 1 0 0 1 1 1 1 Sec34-like family Exo70 PF03081.15 EPS29925.1 - 0.074 12.1 1.5 1.5 7.8 0.0 2.9 4 0 0 4 4 4 0 Exo70 exocyst complex subunit RCC1 PF00415.18 EPS29926.1 - 6.2e-28 97.2 4.6 5.4e-07 30.1 0.0 7.0 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EPS29926.1 - 1.7e-19 69.1 13.5 7.8e-14 51.0 0.1 5.8 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat adh_short PF00106.25 EPS29927.1 - 3.7e-22 78.8 0.0 5.5e-21 74.9 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS29927.1 - 1.5e-14 54.1 0.0 1.5e-13 50.8 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPS29927.1 - 1.5e-05 25.0 0.0 2e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 KR domain PUF PF00806.19 EPS29928.1 - 2.5e-11 42.6 0.0 0.86 9.4 0.0 7.1 7 0 0 7 7 7 4 Pumilio-family RNA binding repeat DUF488 PF04343.13 EPS29928.1 - 0.13 12.9 0.7 1.7 9.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF488 Pectate_lyase22 PF14583.6 EPS29928.1 - 0.17 10.5 0.0 0.27 9.8 0.0 1.2 1 0 0 1 1 1 0 Oligogalacturonate lyase Whi5 PF08528.11 EPS29929.1 - 0.0023 17.5 0.1 0.0046 16.5 0.1 1.5 1 0 0 1 1 1 1 Whi5 like Metallopep PF12044.8 EPS29931.1 - 5.9e-168 558.9 0.0 7.3e-168 558.6 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_5 PF13688.6 EPS29931.1 - 0.0056 16.8 0.1 0.01 16.0 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 EPS29931.1 - 0.092 13.3 0.2 0.23 12.0 0.2 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like MRG PF05712.13 EPS29931.1 - 0.2 10.9 0.0 0.36 10.1 0.0 1.3 1 0 0 1 1 1 0 MRG Reprolysin_2 PF13574.6 EPS29931.1 - 0.53 10.1 2.3 1.7 8.5 2.3 1.9 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like AP3D1 PF06375.11 EPS29932.1 - 0.021 15.1 7.4 0.024 14.9 7.4 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 AIF_C PF14721.6 EPS29932.1 - 0.043 14.2 1.9 0.055 13.8 1.9 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Atrophin-1 PF03154.15 EPS29932.1 - 0.34 9.2 11.6 0.41 8.9 11.6 1.1 1 0 0 1 1 1 0 Atrophin-1 family MFS_3 PF05977.13 EPS29932.1 - 0.48 8.7 0.9 0.56 8.5 0.9 1.0 1 0 0 1 1 1 0 Transmembrane secretion effector Connexin PF00029.19 EPS29932.1 - 1.4 8.7 4.2 1.5 8.5 4.2 1.1 1 0 0 1 1 1 0 Connexin Cytomega_UL84 PF06284.11 EPS29932.1 - 5.5 5.3 6.2 6.4 5.1 6.2 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein CP2 PF04516.15 EPS29934.1 - 8.1e-78 260.9 0.0 1.3e-77 260.2 0.0 1.3 1 0 0 1 1 1 1 CP2 transcription factor Par3_HAL_N_term PF12053.8 EPS29934.1 - 0.21 11.8 0.3 0.43 10.8 0.3 1.5 1 0 0 1 1 1 0 N-terminal of Par3 and HAL proteins ubiquitin PF00240.23 EPS29934.1 - 0.22 11.3 0.6 29 4.5 0.0 2.8 2 0 0 2 2 2 0 Ubiquitin family DNA_ligase_A_M PF01068.21 EPS29937.1 - 3.1e-51 173.9 0.1 2.4e-48 164.5 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EPS29937.1 - 4.2e-38 131.4 0.1 9.9e-38 130.2 0.1 1.7 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EPS29937.1 - 1.7e-19 70.2 0.0 5.3e-19 68.7 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RINT1_TIP1 PF04437.13 EPS29938.1 - 1.9e-181 604.3 0.0 4.1e-181 603.2 0.0 1.5 2 0 0 2 2 2 1 RINT-1 / TIP-1 family HSR PF03172.13 EPS29938.1 - 0.029 14.5 0.1 0.8 9.9 0.0 2.5 2 0 0 2 2 2 0 HSR domain WASH-7_mid PF14744.6 EPS29938.1 - 0.045 12.8 0.8 0.074 12.1 0.8 1.2 1 0 0 1 1 1 0 WASH complex subunit 7 Efg1 PF10153.9 EPS29938.1 - 0.063 13.6 5.6 0.15 12.4 5.6 1.6 1 0 0 1 1 1 0 rRNA-processing protein Efg1 CRISPR_Cse2 PF09485.10 EPS29938.1 - 0.39 11.3 7.2 1.1 9.7 6.6 2.2 1 1 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) Acyl-CoA_dh_C PF12806.7 EPS29938.1 - 0.54 10.4 3.8 26 5.0 1.6 3.4 3 0 0 3 3 3 0 Acetyl-CoA dehydrogenase C-terminal like Pyridoxal_deC PF00282.19 EPS29939.1 - 5e-78 262.4 0.0 6.8e-77 258.7 0.0 2.1 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EPS29939.1 - 3.6e-05 22.9 0.0 5.5e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EPS29939.1 - 0.0036 16.6 0.0 0.0064 15.8 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Trp_syntA PF00290.20 EPS29940.1 - 1.2e-94 316.0 0.0 2e-94 315.3 0.0 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 EPS29940.1 - 9.5e-47 159.8 2.6 1.7e-46 159.0 2.6 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Clathrin PF00637.20 EPS29941.1 - 1e-21 77.3 0.2 1.1e-19 70.7 0.2 2.8 3 0 0 3 3 3 1 Region in Clathrin and VPS Vps39_1 PF10366.9 EPS29941.1 - 0.015 15.6 0.7 0.032 14.5 0.1 1.8 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 TPR_2 PF07719.17 EPS29941.1 - 0.088 13.0 0.2 4.1 7.8 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat BSP_II PF05432.11 EPS29941.1 - 0.14 11.8 6.2 0.24 11.1 6.2 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) zf-RING_5 PF14634.6 EPS29941.1 - 0.17 11.9 0.2 0.33 10.9 0.2 1.4 1 0 0 1 1 1 0 zinc-RING finger domain DUF913 PF06025.12 EPS29941.1 - 0.23 10.4 0.9 0.33 9.9 0.2 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) BUD22 PF09073.10 EPS29941.1 - 1.9 7.8 8.3 3.3 6.9 8.3 1.3 1 0 0 1 1 1 0 BUD22 RXT2_N PF08595.11 EPS29941.1 - 3.7 7.5 6.4 8.2 6.4 6.4 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal DNA_pol_phi PF04931.13 EPS29941.1 - 9.3 4.2 16.9 14 3.6 16.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF155 PF02582.14 EPS29942.1 - 8.2e-48 162.8 0.0 1.1e-47 162.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 FeoB_associated PF12669.7 EPS29942.1 - 0.077 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Ribonuclease_T2 PF00445.18 EPS29943.1 - 2.1e-42 145.4 1.1 3.3e-42 144.8 0.1 1.7 2 1 0 2 2 2 1 Ribonuclease T2 family GT-D PF08759.11 EPS29943.1 - 0.0064 16.2 0.1 0.01 15.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase GT-D fold GFO_IDH_MocA PF01408.22 EPS29944.1 - 1e-19 71.5 0.0 1.7e-19 70.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EPS29944.1 - 3e-05 24.0 0.0 5.7e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DUF1115 PF06544.12 EPS29945.1 - 1.4e-11 44.7 0.0 3.3e-11 43.5 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1115) Rgp1 PF08737.10 EPS29945.1 - 0.14 11.3 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Rgp1 zf-H2C2_2 PF13465.6 EPS29946.1 - 5.8e-11 42.3 3.7 0.00021 21.6 0.2 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 EPS29946.1 - 3.5e-07 30.3 16.9 0.00083 19.7 2.8 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPS29946.1 - 1.3e-06 28.8 13.2 0.0018 18.9 2.1 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EPS29946.1 - 2.6e-06 27.3 4.2 0.0065 16.4 2.4 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EPS29946.1 - 0.022 15.1 1.1 0.057 13.7 0.6 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 EPS29946.1 - 0.13 12.1 0.8 2.5 8.0 0.3 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HE PF16278.5 EPS29946.1 - 0.17 12.4 4.7 0.12 12.8 1.9 2.2 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger ubiquitin PF00240.23 EPS29947.1 - 4.3e-34 116.1 0.6 7.9e-34 115.2 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 EPS29947.1 - 1.2e-26 92.6 1.8 1.2e-26 92.6 1.8 1.8 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 EPS29947.1 - 2.7e-16 59.2 0.7 4.9e-16 58.3 0.7 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EPS29947.1 - 2.7e-05 24.6 0.4 0.00013 22.4 0.1 2.1 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EPS29947.1 - 0.0013 18.8 0.6 0.0029 17.7 0.6 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 EPS29947.1 - 0.0042 17.4 0.9 0.0079 16.5 0.0 1.8 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EPS29947.1 - 0.0054 16.6 0.0 0.0082 16.1 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 EPS29947.1 - 0.013 16.0 0.7 0.019 15.5 0.7 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 EPS29947.1 - 0.021 14.9 1.0 5.9 7.0 0.2 2.3 2 0 0 2 2 2 0 Ubiquitin-like domain IBR PF01485.21 EPS29947.1 - 0.028 14.6 0.2 0.048 13.9 0.2 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Glyco_hydro_18 PF00704.28 EPS29948.1 - 1.2e-81 274.8 0.0 1.4e-81 274.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Proteasome PF00227.26 EPS29950.1 - 4.9e-50 169.7 0.2 6.9e-50 169.2 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EPS29950.1 - 5.2e-13 48.4 0.3 8.3e-13 47.8 0.3 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Amidase_5 PF05382.13 EPS29950.1 - 0.058 13.3 0.1 2.8 7.9 0.0 2.4 2 0 0 2 2 2 0 Bacteriophage peptidoglycan hydrolase Ribophorin_II PF05817.14 EPS29950.1 - 0.095 11.2 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II DUF2373 PF10180.9 EPS29951.1 - 6.6e-20 70.7 0.1 2.2e-19 69.0 0.1 2.0 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2373) Cwf_Cwc_15 PF04889.12 EPS29951.1 - 0.0016 18.2 26.5 0.0016 18.2 26.5 2.8 2 1 1 3 3 3 1 Cwf15/Cwc15 cell cycle control protein Na_trans_assoc PF06512.13 EPS29951.1 - 0.014 15.7 10.1 0.014 15.7 10.1 2.7 3 0 0 3 3 3 0 Sodium ion transport-associated GCP_C_terminal PF04130.13 EPS29952.1 - 6.1e-102 341.2 0.1 1.6e-101 339.8 0.1 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EPS29952.1 - 1.2e-84 284.6 0.0 7.1e-84 282.0 0.0 2.0 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal Aft1_HRA PF11786.8 EPS29953.1 - 4.7e-25 87.7 9.2 4.7e-25 87.7 9.2 3.4 2 1 1 3 3 3 1 Aft1 HRA domain Aft1_OSA PF11785.8 EPS29953.1 - 1.1e-21 77.1 9.3 1.1e-21 77.1 9.3 3.4 3 0 0 3 3 3 1 Aft1 osmotic stress response (OSM) domain Aft1_HRR PF11787.8 EPS29953.1 - 2.7e-19 70.1 4.6 2.7e-19 70.1 4.6 3.5 3 1 0 3 3 3 1 Aft1 HRR domain bZIP_1 PF00170.21 EPS29953.1 - 1e-12 47.9 4.6 1.8e-12 47.2 4.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EPS29953.1 - 1.2e-05 25.2 5.7 2.6e-05 24.2 5.7 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 EPS29953.1 - 0.0027 18.2 2.1 0.0027 18.2 2.1 1.8 2 0 0 2 2 2 1 bZIP Maf transcription factor FAM76 PF16046.5 EPS29953.1 - 3.3 7.0 12.2 0.23 10.8 6.6 1.7 1 1 1 2 2 2 0 FAM76 protein Cg6151-P PF10233.9 EPS29954.1 - 2.6e-42 143.7 14.7 3e-42 143.5 14.7 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P COPI_assoc PF08507.10 EPS29954.1 - 0.68 10.0 11.6 1.6 8.8 11.7 1.6 1 1 0 1 1 1 0 COPI associated protein LMBR1 PF04791.16 EPS29954.1 - 0.82 8.5 8.0 1.5 7.6 8.0 1.5 1 1 0 1 1 1 0 LMBR1-like membrane protein Cthe_2159 PF14262.6 EPS29955.1 - 0.084 12.2 0.0 0.084 12.2 0.0 1.1 1 0 0 1 1 1 0 Carbohydrate-binding domain-containing protein Cthe_2159 DUF4969 PF16339.5 EPS29955.1 - 0.13 12.6 0.1 0.16 12.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4969) Aim21 PF11489.8 EPS29956.1 - 7e-237 788.9 72.5 7e-237 788.9 72.5 2.1 2 0 0 2 2 2 1 Altered inheritance of mitochondria protein 21 ATP_sub_h PF10775.9 EPS29957.1 - 4.3e-28 97.1 1.7 6.4e-28 96.5 1.7 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h TFIIB PF00382.19 EPS29958.1 - 2.9e-36 123.3 0.0 1.2e-18 66.9 0.1 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 EPS29958.1 - 1.8e-09 37.0 1.0 1.8e-09 37.0 1.0 1.8 2 0 0 2 2 2 1 TFIIB zinc-binding Cyclin_N PF00134.23 EPS29958.1 - 0.00025 20.8 0.0 0.87 9.3 0.0 2.2 2 0 0 2 2 2 2 Cyclin, N-terminal domain RB_B PF01857.20 EPS29958.1 - 0.00067 19.7 0.0 0.0024 17.9 0.0 1.8 2 0 0 2 2 2 1 Retinoblastoma-associated protein B domain Sigma70_r4_2 PF08281.12 EPS29958.1 - 0.025 14.3 0.0 0.055 13.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 Cyclin_C PF02984.19 EPS29958.1 - 0.032 14.3 0.0 5 7.2 0.0 2.4 2 1 0 2 2 2 0 Cyclin, C-terminal domain HTH_Tnp_ISL3 PF13542.6 EPS29958.1 - 0.035 13.5 0.0 0.086 12.3 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_23 PF13384.6 EPS29958.1 - 0.038 13.8 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 Homeodomain-like domain GerE PF00196.19 EPS29958.1 - 0.18 11.4 0.0 0.36 10.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family zf-ribbon_3 PF13248.6 EPS29958.1 - 3.7 7.1 8.6 1.1 8.8 3.2 2.7 2 1 0 2 2 2 0 zinc-ribbon domain eIF-5_eIF-2B PF01873.17 EPS29958.1 - 5.4 6.9 5.9 1.5 8.7 0.2 2.5 2 1 0 3 3 3 0 Domain found in IF2B/IF5 RAG2_PHD PF13341.6 EPS29959.1 - 0.018 15.0 0.2 0.033 14.2 0.2 1.3 1 0 0 1 1 1 0 RAG2 PHD domain DUF1765 PF08578.10 EPS29960.1 - 3.3e-44 150.4 4.7 3.3e-44 150.4 4.7 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) TPP_enzyme_N PF02776.18 EPS29961.1 - 2e-32 112.2 0.2 3.2e-32 111.5 0.2 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EPS29961.1 - 2.2e-19 69.6 0.0 4.8e-19 68.4 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EPS29961.1 - 3.5e-16 59.3 1.5 2.3e-14 53.5 0.0 3.3 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Zn_clus PF00172.18 EPS29962.1 - 8.6e-06 25.8 10.2 1.6e-05 24.9 10.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPS29962.1 - 0.0024 17.0 0.7 0.013 14.5 0.0 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain But2 PF09792.9 EPS29963.1 - 7.5e-59 198.2 2.8 1.5e-58 197.3 2.8 1.5 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain MFS_1 PF07690.16 EPS29964.1 - 5.2e-31 107.8 40.2 5.2e-31 107.8 40.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Cutinase PF01083.22 EPS29965.1 - 1.6e-43 148.7 1.6 1.6e-43 148.7 1.6 1.5 2 0 0 2 2 2 1 Cutinase PE-PPE PF08237.11 EPS29965.1 - 0.0024 17.4 0.3 0.0043 16.6 0.3 1.4 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_2 PF02230.16 EPS29965.1 - 0.017 15.0 0.0 0.028 14.2 0.0 1.4 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 EPS29965.1 - 0.017 14.4 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EPS29965.1 - 0.018 14.7 0.1 0.033 13.9 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold TFR_dimer PF04253.15 EPS29966.1 - 1.8e-37 128.1 0.1 3.3e-37 127.3 0.1 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 EPS29966.1 - 9.2e-17 61.4 0.0 3.1e-16 59.7 0.0 1.9 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 EPS29966.1 - 4.9e-15 55.3 0.0 1e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 PA domain DIM1 PF02966.16 EPS29967.1 - 4.6e-70 233.6 0.3 5.1e-70 233.4 0.3 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 EPS29967.1 - 0.0047 16.9 0.0 0.006 16.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DUF3192 PF11399.8 EPS29967.1 - 0.077 13.0 0.1 0.099 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3192) Translin PF01997.16 EPS29968.1 - 6.5e-50 170.0 0.0 7.5e-50 169.8 0.0 1.0 1 0 0 1 1 1 1 Translin family DUF5631 PF18645.1 EPS29968.1 - 0.029 14.8 0.5 0.067 13.6 0.5 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5631) FRQ PF09421.10 EPS29968.1 - 0.22 9.5 0.1 0.27 9.2 0.1 1.0 1 0 0 1 1 1 0 Frequency clock protein Rx_N PF18052.1 EPS29968.1 - 0.24 11.7 1.6 18 5.7 0.7 3.2 2 1 0 2 2 2 0 Rx N-terminal domain GSHPx PF00255.19 EPS29969.1 - 8.1e-38 128.3 0.0 1e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 EPS29969.1 - 0.0052 16.7 0.0 0.009 15.9 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Pcc1 PF09341.10 EPS29970.1 - 4.8e-33 113.1 0.1 6e-33 112.8 0.1 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 DUF2336 PF10098.9 EPS29970.1 - 0.036 13.5 0.1 0.042 13.3 0.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2336) DSPn PF14671.6 EPS29972.1 - 9.1e-43 146.1 0.0 1.1e-40 139.3 0.0 2.7 2 1 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EPS29972.1 - 4.8e-16 58.8 0.0 1.5e-15 57.2 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EPS29972.1 - 1.8e-05 24.4 0.0 4.3e-05 23.2 0.0 1.5 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Fungal_trans_2 PF11951.8 EPS29973.1 - 0.0001 21.3 0.4 0.00014 20.8 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_1 PF00561.20 EPS29975.1 - 1.1e-19 71.1 0.3 2e-19 70.2 0.3 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EPS29975.1 - 5.1e-16 58.7 0.1 9.1e-16 57.8 0.1 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EPS29975.1 - 5.8e-16 59.8 0.6 7.5e-16 59.4 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 EPS29975.1 - 1.1e-05 24.2 0.0 1.7e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Ndr family DUF915 PF06028.11 EPS29975.1 - 0.00041 19.8 0.1 0.00057 19.3 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Eno-Rase_NADH_b PF12242.8 EPS29975.1 - 0.00047 19.9 0.0 0.0011 18.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PGAP1 PF07819.13 EPS29975.1 - 0.0016 18.2 0.0 0.0023 17.7 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Say1_Mug180 PF10340.9 EPS29975.1 - 0.0026 16.7 0.1 0.0063 15.4 0.1 1.5 1 1 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_5 PF12695.7 EPS29975.1 - 0.0034 17.2 0.0 0.0064 16.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 EPS29975.1 - 0.0052 16.3 0.0 0.0084 15.6 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Chlorophyllase2 PF12740.7 EPS29975.1 - 0.012 14.6 0.0 0.069 12.0 0.0 2.1 2 1 0 2 2 2 0 Chlorophyllase enzyme Chlorophyllase PF07224.11 EPS29975.1 - 0.027 13.5 0.0 0.099 11.6 0.0 1.9 2 1 0 2 2 2 0 Chlorophyllase Esterase PF00756.20 EPS29975.1 - 0.029 14.0 0.0 0.043 13.5 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.13 EPS29975.1 - 0.037 13.9 0.5 0.12 12.2 0.5 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 EPS29975.1 - 0.069 13.0 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF900 PF05990.12 EPS29975.1 - 0.13 11.8 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Lipase_2 PF01674.18 EPS29975.1 - 0.13 11.8 0.0 0.27 10.7 0.0 1.4 1 1 0 1 1 1 0 Lipase (class 2) DUF1057 PF06342.12 EPS29975.1 - 0.23 10.5 0.0 0.35 9.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Fungal_trans PF04082.18 EPS29977.1 - 2.7e-09 36.4 0.1 4.7e-09 35.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS29977.1 - 8.9e-06 25.7 11.2 1.8e-05 24.7 11.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-RING_2 PF13639.6 EPS29978.1 - 8.4e-12 45.2 7.3 1.2e-11 44.7 7.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EPS29978.1 - 3e-09 36.6 5.0 4.6e-09 36.0 5.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EPS29978.1 - 5.1e-09 35.7 2.0 5.1e-09 35.7 2.0 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 EPS29978.1 - 4.6e-08 32.8 4.6 7e-08 32.2 4.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPS29978.1 - 2.7e-07 30.5 0.4 2.7e-07 30.5 0.4 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EPS29978.1 - 3.4e-05 23.7 6.7 5.6e-05 23.0 6.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EPS29978.1 - 6.3e-05 23.2 8.3 0.00016 21.9 8.3 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EPS29978.1 - 0.00034 20.4 10.1 0.0018 18.1 3.2 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EPS29978.1 - 0.0014 18.5 4.7 0.0023 17.8 4.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SKG6 PF08693.10 EPS29978.1 - 0.0081 15.5 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Zn_ribbon_17 PF17120.5 EPS29978.1 - 0.0094 15.6 10.9 0.01 15.5 8.6 2.1 2 1 0 2 2 2 1 Zinc-ribbon, C4HC2 type Mid2 PF04478.12 EPS29978.1 - 0.019 14.8 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor zf-ANAPC11 PF12861.7 EPS29978.1 - 0.036 14.1 4.3 0.065 13.3 4.3 1.4 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_Tnp_IS1595 PF12760.7 EPS29978.1 - 0.041 13.9 6.4 0.092 12.7 1.1 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-RING_4 PF14570.6 EPS29978.1 - 0.07 12.9 4.9 0.15 11.9 4.8 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF2730 PF10805.8 EPS29978.1 - 0.081 13.0 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) PhnA_Zn_Ribbon PF08274.12 EPS29978.1 - 0.099 12.6 1.2 1.2 9.2 0.2 2.3 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Rtf2 PF04641.12 EPS29978.1 - 0.11 11.8 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger zf-C3HC4_4 PF15227.6 EPS29978.1 - 0.12 12.6 6.4 7.2 6.9 5.8 2.3 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Elf1 PF05129.13 EPS29978.1 - 0.46 10.6 3.6 2.2 8.4 0.3 2.3 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-RING-like PF08746.11 EPS29978.1 - 0.56 10.6 5.3 0.88 9.9 5.3 1.3 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.8 EPS29978.1 - 0.62 10.3 8.2 5.8 7.2 8.2 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.8 EPS29978.1 - 0.77 9.6 3.2 1.2 9.0 3.2 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit RINGv PF12906.7 EPS29978.1 - 2.5 8.3 11.6 0.13 12.4 6.4 1.6 2 0 0 2 2 1 0 RING-variant domain Zf_RING PF16744.5 EPS29978.1 - 2.9 8.1 8.1 1.5 9.0 5.4 1.8 1 1 1 2 2 2 0 KIAA1045 RING finger PHD PF00628.29 EPS29978.1 - 4.3 7.3 7.8 14 5.6 7.9 1.9 1 1 0 1 1 1 0 PHD-finger zf-HYPF PF07503.12 EPS29978.1 - 6.5 6.6 8.9 0.43 10.4 0.4 2.5 3 0 0 3 3 2 0 HypF finger Pap_E4 PF02711.14 EPS29979.1 - 2.7 9.0 11.9 0.83 10.7 6.8 2.1 1 1 1 2 2 2 0 E4 protein DUF2457 PF10446.9 EPS29979.1 - 5 6.2 8.7 6.2 5.9 8.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Homeodomain PF00046.29 EPS29981.1 - 4.1e-15 55.4 3.4 9.3e-15 54.2 3.4 1.6 1 0 0 1 1 1 1 Homeodomain Uma2 PF05685.12 EPS29982.1 - 0.0036 16.9 0.0 0.0052 16.3 0.0 1.4 1 1 0 1 1 1 1 Putative restriction endonuclease Amino_oxidase PF01593.24 EPS29983.1 - 7.6e-43 147.4 3.3 8e-41 140.8 3.3 2.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EPS29983.1 - 9.4e-15 54.6 1.4 2.2e-14 53.4 1.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EPS29983.1 - 3.2e-05 23.3 0.3 5.8e-05 22.5 0.3 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPS29983.1 - 0.00019 21.9 0.3 0.00033 21.2 0.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EPS29983.1 - 0.012 14.4 0.5 0.018 13.8 0.5 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 EPS29983.1 - 0.013 14.8 0.6 0.022 14.0 0.6 1.2 1 0 0 1 1 1 0 FAD binding domain AlaDh_PNT_C PF01262.21 EPS29983.1 - 0.019 14.3 0.1 0.029 13.7 0.1 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 EPS29983.1 - 0.02 14.2 0.5 0.033 13.4 0.5 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.24 EPS29983.1 - 0.026 13.6 2.1 0.044 12.9 2.1 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 EPS29983.1 - 0.046 13.7 0.4 0.21 11.6 0.2 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.24 EPS29983.1 - 0.058 13.0 3.9 0.22 11.1 4.0 2.1 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EPS29983.1 - 0.099 12.0 1.7 0.15 11.4 1.7 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 EPS29983.1 - 0.16 11.8 0.2 0.28 11.0 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 EPS29983.1 - 0.45 9.5 1.3 0.65 9.0 1.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF2235 PF09994.9 EPS29985.1 - 1.2e-102 343.2 0.0 1.9e-102 342.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) An_peroxidase PF03098.15 EPS29986.1 - 7.5e-38 130.4 0.0 1.8e-20 73.1 0.0 3.2 1 1 2 3 3 3 3 Animal haem peroxidase PilP PF04351.13 EPS29986.1 - 0.098 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Pilus assembly protein, PilP Hexapep PF00132.24 EPS29987.1 - 5.9e-09 35.3 8.2 9.5e-05 22.0 1.9 4.6 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EPS29987.1 - 0.00019 21.1 0.2 0.00019 21.1 0.2 2.6 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase Glycos_transf_1 PF00534.20 EPS29988.1 - 1.4e-18 67.0 0.0 4.9e-18 65.2 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EPS29988.1 - 8.7e-14 52.1 0.0 1.7e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EPS29988.1 - 2.4e-06 27.8 0.0 5.3e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Ribosomal_S14 PF00253.21 EPS29989.1 - 6.7e-22 77.0 0.4 1.4e-21 76.0 0.4 1.6 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Synaphin PF05835.12 EPS29989.1 - 0.032 14.5 0.3 0.042 14.1 0.3 1.2 1 0 0 1 1 1 0 Synaphin protein DJ-1_PfpI PF01965.24 EPS29991.1 - 1.3e-08 34.9 0.0 5.8e-08 32.7 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family Prefoldin PF02996.17 EPS29992.1 - 1.2e-29 102.6 0.3 1.5e-29 102.3 0.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 EPS29992.1 - 0.001 19.0 0.4 0.0022 17.9 0.1 1.7 2 1 0 2 2 2 1 Prefoldin subunit DUF1128 PF06569.11 EPS29992.1 - 0.0014 18.6 0.0 0.0051 16.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1128) DUF4201 PF13870.6 EPS29992.1 - 0.016 15.0 0.2 0.091 12.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) FlaC_arch PF05377.11 EPS29992.1 - 0.042 14.2 0.3 1.6 9.1 0.1 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Vma12 PF11712.8 EPS29993.1 - 2.4e-40 137.8 0.0 3.6e-40 137.3 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Amidohydro_1 PF01979.20 EPS29994.1 - 2.1e-26 93.0 0.0 1.2e-25 90.6 0.0 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EPS29994.1 - 7.6e-13 48.7 0.0 6.1e-08 32.6 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family 5-nucleotidase PF06189.12 EPS29994.1 - 0.22 10.4 0.0 0.37 9.7 0.0 1.2 1 0 0 1 1 1 0 5'-nucleotidase GRAM PF02893.20 EPS29996.1 - 6.4e-35 119.5 2.1 1.4e-22 79.7 0.0 3.5 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.20 EPS29996.1 - 3.9e-26 91.8 0.0 7.3e-26 90.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.29 EPS29996.1 - 4.5e-15 56.0 0.1 1.8e-13 50.9 0.0 3.0 3 0 0 3 3 3 1 PH domain PH_11 PF15413.6 EPS29996.1 - 5.5e-07 30.0 0.1 2.2e-06 28.0 0.1 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 EPS29996.1 - 1.5e-05 25.1 0.0 5.5e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 EPS29996.1 - 0.0013 18.8 0.0 0.0034 17.5 0.0 1.6 1 0 0 1 1 1 1 PH domain UDPGT PF00201.18 EPS29996.1 - 0.026 13.3 0.1 0.062 12.1 0.1 1.6 1 1 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase DUF4785 PF16024.5 EPS29996.1 - 0.082 11.6 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4785) RNA_polI_A34 PF08208.11 EPS29997.1 - 2.3e-43 148.7 17.1 2.3e-43 148.7 17.1 2.4 2 1 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 Serglycin PF04360.12 EPS29997.1 - 3 7.8 8.5 5.9 6.8 7.9 1.8 2 0 0 2 2 2 0 Serglycin SR-25 PF10500.9 EPS29997.1 - 3.9 7.0 41.8 4.4 6.9 20.5 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CLP1_P PF16575.5 EPS29998.1 - 1.3e-25 90.3 0.0 2.9e-25 89.2 0.0 1.6 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_33 PF13671.6 EPS29998.1 - 0.015 15.4 0.7 0.074 13.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EPS29998.1 - 0.048 14.2 0.0 0.31 11.6 0.0 2.4 3 0 0 3 3 3 0 AAA domain G-alpha PF00503.20 EPS29998.1 - 0.22 10.6 0.0 0.39 9.8 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit Prenylcys_lyase PF07156.14 EPS30000.1 - 5.2e-94 315.3 0.0 6.3e-94 315.1 0.0 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.6 EPS30000.1 - 1.3e-12 47.7 0.1 3.5e-12 46.4 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EPS30000.1 - 5.5e-08 32.5 0.0 1.2e-07 31.4 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.24 EPS30000.1 - 9.5e-06 25.4 0.5 0.00042 20.0 0.5 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EPS30000.1 - 0.0081 16.2 0.1 0.022 14.8 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EPS30000.1 - 0.013 14.8 0.0 0.074 12.3 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPS30000.1 - 0.063 13.8 0.3 1.8 9.2 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PDCD2_C PF04194.13 EPS30001.1 - 8.8e-43 146.4 0.0 1.2e-41 142.7 0.0 2.1 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain APH PF01636.23 EPS30002.1 - 4.7e-07 30.0 0.2 1.9e-06 28.0 0.2 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPS30002.1 - 8.3e-05 22.3 0.0 0.00013 21.6 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase CSN8_PSD8_EIF3K PF10075.9 EPS30003.1 - 9.1e-48 161.9 0.1 1.3e-47 161.4 0.1 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Folliculin PF11704.8 EPS30004.1 - 1.1e-51 175.4 0.0 1.5e-51 174.9 0.0 1.2 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport SGT1 PF07093.11 EPS30007.1 - 9.6e-95 318.2 18.5 7.1e-85 285.6 0.1 2.0 1 1 1 2 2 2 2 SGT1 protein IreB PF06135.12 EPS30007.1 - 0.11 12.8 0.0 2 8.7 0.0 2.4 2 0 0 2 2 2 0 IreB regulatory phosphoprotein Cnn_1N PF07989.11 EPS30008.1 - 2.7e-24 85.1 6.6 2.7e-24 85.1 6.6 15.4 3 3 11 14 14 14 1 Centrosomin N-terminal motif 1 PACT_coil_coil PF10495.9 EPS30008.1 - 1.6e-21 76.7 4.0 1.6e-21 76.7 4.0 4.3 2 0 0 2 2 2 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Fez1 PF06818.15 EPS30008.1 - 0.00023 21.7 19.6 0.00023 21.7 19.6 8.2 1 1 3 5 5 5 3 Fez1 Bacillus_HBL PF05791.11 EPS30008.1 - 0.00037 20.4 3.7 0.00037 20.4 3.7 7.9 3 2 6 11 11 11 1 Bacillus haemolytic enterotoxin (HBL) DUF4200 PF13863.6 EPS30008.1 - 0.004 17.6 13.8 0.004 17.6 13.8 12.8 5 4 4 12 12 12 1 Domain of unknown function (DUF4200) Spc110_C PF18520.1 EPS30008.1 - 0.12 12.0 2.5 0.31 10.7 0.3 3.0 2 0 0 2 2 2 0 Spindle pole body component 110 C-terminal domain Halo_GVPC PF05465.13 EPS30008.1 - 6.6 7.1 6.7 8 6.8 0.6 3.5 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat AAA PF00004.29 EPS30009.1 - 8.7e-42 142.7 0.0 1.6e-41 141.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EPS30009.1 - 2.7e-29 100.9 0.0 1e-28 99.1 0.1 2.1 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 EPS30009.1 - 4.6e-24 84.3 2.7 4.6e-24 84.3 2.7 1.9 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 EPS30009.1 - 1.4e-06 28.0 0.1 8.9e-06 25.4 0.0 2.4 3 0 0 3 3 2 1 AAA+ lid domain AAA_16 PF13191.6 EPS30009.1 - 6.6e-06 26.6 0.1 0.0015 18.9 0.0 2.6 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EPS30009.1 - 6.7e-06 25.9 0.0 1.5e-05 24.8 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 EPS30009.1 - 4e-05 22.9 0.0 0.00088 18.5 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 EPS30009.1 - 4.9e-05 23.3 0.0 0.00023 21.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EPS30009.1 - 5.9e-05 22.9 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 EPS30009.1 - 6.5e-05 23.3 0.0 0.012 15.9 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_22 PF13401.6 EPS30009.1 - 6.7e-05 23.2 0.1 0.02 15.2 0.0 2.7 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 EPS30009.1 - 0.00015 21.1 0.0 0.00026 20.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 EPS30009.1 - 0.00034 20.6 0.0 0.00068 19.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 EPS30009.1 - 0.00048 20.3 0.0 0.011 15.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 EPS30009.1 - 0.00063 20.3 0.1 0.0026 18.3 0.0 2.1 2 1 0 2 2 1 1 AAA domain AAA_33 PF13671.6 EPS30009.1 - 0.0017 18.6 0.0 0.0053 16.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EPS30009.1 - 0.0028 17.4 0.0 0.0095 15.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EPS30009.1 - 0.0055 16.3 0.1 0.64 9.6 0.1 2.9 2 1 1 3 3 3 1 AAA domain USP8_dimer PF08969.11 EPS30009.1 - 0.009 16.2 3.2 0.022 15.0 3.2 1.7 1 0 0 1 1 1 1 USP8 dimerisation domain Mg_chelatase PF01078.21 EPS30009.1 - 0.017 14.5 0.2 0.069 12.5 0.1 2.1 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EPS30009.1 - 0.021 14.3 0.1 0.12 11.9 0.0 2.2 2 1 0 2 2 2 0 P-loop containing dynein motor region Torsin PF06309.11 EPS30009.1 - 0.025 14.7 0.1 0.096 12.8 0.0 1.9 2 0 0 2 2 2 0 Torsin Parvo_NS1 PF01057.17 EPS30009.1 - 0.061 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_17 PF13207.6 EPS30009.1 - 0.061 13.7 0.0 0.061 13.7 0.0 2.4 3 0 0 3 3 1 0 AAA domain NACHT PF05729.12 EPS30009.1 - 0.071 13.0 0.0 0.69 9.8 0.0 2.2 1 1 1 2 2 2 0 NACHT domain PhoH PF02562.16 EPS30009.1 - 0.076 12.5 0.1 0.16 11.4 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein ATPase_2 PF01637.18 EPS30009.1 - 0.086 12.7 1.5 1.2 9.0 0.0 2.7 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea AFG1_ATPase PF03969.16 EPS30009.1 - 0.16 10.8 0.0 0.28 10.0 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase Cytidylate_kin PF02224.18 EPS30009.1 - 0.22 11.2 1.1 0.51 10.0 0.0 2.1 2 1 1 3 3 3 0 Cytidylate kinase Prefoldin_2 PF01920.20 EPS30010.1 - 5.2e-22 77.8 17.0 6.8e-22 77.4 17.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.6 EPS30010.1 - 0.00081 19.4 6.8 0.0011 18.9 6.8 1.2 1 0 0 1 1 1 1 Prefoldin subunit DUF3727 PF12527.8 EPS30010.1 - 0.0013 19.0 5.6 0.23 11.7 0.9 2.5 1 1 2 3 3 3 2 Protein of unknown function (DUF3727) Spc7 PF08317.11 EPS30010.1 - 0.004 16.1 17.5 0.0053 15.7 17.5 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein Prefoldin PF02996.17 EPS30010.1 - 0.0083 16.0 16.8 0.035 14.0 16.8 1.9 1 1 0 1 1 1 1 Prefoldin subunit PHM7_cyt PF14703.6 EPS30010.1 - 0.03 14.6 8.9 0.047 13.9 8.9 1.3 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter betaPIX_CC PF16523.5 EPS30010.1 - 0.034 14.0 12.3 0.68 9.8 3.7 2.2 2 0 0 2 2 2 0 betaPIX coiled coil ANAPC_CDC26 PF10471.9 EPS30010.1 - 0.052 14.4 2.8 0.052 14.4 2.8 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 FliJ PF02050.16 EPS30010.1 - 0.056 13.7 18.3 0.12 12.6 4.9 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein CENP-F_leu_zip PF10473.9 EPS30010.1 - 0.063 13.3 20.5 0.19 11.8 4.2 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Occludin_ELL PF07303.13 EPS30010.1 - 0.1 13.3 1.1 0.1 13.3 1.1 2.2 2 0 0 2 2 2 0 Occludin homology domain DHR10 PF18595.1 EPS30010.1 - 0.15 12.2 19.5 0.066 13.3 4.7 2.1 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain KxDL PF10241.9 EPS30010.1 - 0.16 12.3 0.2 0.16 12.3 0.2 3.1 2 2 1 3 3 3 0 Uncharacterized conserved protein Spc24 PF08286.11 EPS30010.1 - 0.19 12.0 17.1 0.029 14.6 4.6 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF5082 PF16888.5 EPS30010.1 - 0.23 11.7 14.9 2.7 8.3 14.9 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) HAP1_N PF04849.13 EPS30010.1 - 0.24 10.6 18.3 0.53 9.4 12.5 2.0 1 1 1 2 2 2 0 HAP1 N-terminal conserved region TPR_MLP1_2 PF07926.12 EPS30010.1 - 0.26 11.3 18.2 0.58 10.2 4.3 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Siah-Interact_N PF09032.11 EPS30010.1 - 0.32 11.3 13.3 1.9 8.9 1.9 2.3 2 0 0 2 2 2 0 Siah interacting protein, N terminal CREPT PF16566.5 EPS30010.1 - 0.38 10.9 9.3 0.24 11.6 7.3 1.6 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF1779 PF08680.10 EPS30010.1 - 0.44 10.7 8.1 0.45 10.7 8.1 1.0 1 0 0 1 1 1 0 TATA-box binding DASH_Dam1 PF08653.10 EPS30010.1 - 0.45 10.4 4.9 0.2 11.5 1.1 2.2 3 0 0 3 3 3 0 DASH complex subunit Dam1 ERp29 PF07749.12 EPS30010.1 - 0.55 11.2 8.1 1.7 9.6 8.1 1.9 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain APG6_N PF17675.1 EPS30010.1 - 0.78 10.3 23.4 1.6 9.3 8.3 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF4407 PF14362.6 EPS30010.1 - 0.86 8.9 10.4 1.1 8.6 10.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ABC_tran_CTD PF16326.5 EPS30010.1 - 0.91 9.8 17.2 1.6 9.0 1.1 2.9 2 1 0 2 2 2 0 ABC transporter C-terminal domain Rx_N PF18052.1 EPS30010.1 - 0.95 9.8 12.5 0.6 10.4 2.4 2.1 1 1 1 2 2 2 0 Rx N-terminal domain DivIC PF04977.15 EPS30010.1 - 0.98 9.2 21.2 0.3 10.9 2.0 3.3 2 1 1 3 3 3 0 Septum formation initiator NPV_P10 PF05531.12 EPS30010.1 - 1 9.9 9.1 1.8 9.1 4.1 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein bZIP_1 PF00170.21 EPS30010.1 - 1.4 9.1 12.3 1.4 9.1 0.8 3.0 2 1 1 3 3 3 0 bZIP transcription factor XhlA PF10779.9 EPS30010.1 - 2.1 8.6 7.3 0.81 9.9 2.0 2.2 2 0 0 2 2 2 0 Haemolysin XhlA UPF0242 PF06785.11 EPS30010.1 - 2.7 8.0 22.5 6.9 6.7 22.5 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FlaC_arch PF05377.11 EPS30010.1 - 2.8 8.4 12.7 19 5.8 3.4 3.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) BRE1 PF08647.11 EPS30010.1 - 2.9 8.0 18.6 4.8 7.3 6.9 2.5 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Uso1_p115_C PF04871.13 EPS30010.1 - 3.9 7.8 19.0 42 4.5 19.0 2.1 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region YabA PF06156.13 EPS30010.1 - 4.4 8.0 14.5 1.5 9.5 1.6 2.1 2 0 0 2 2 2 0 Initiation control protein YabA CorA PF01544.18 EPS30010.1 - 4.5 6.5 8.8 3.5 6.9 1.1 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Fib_alpha PF08702.10 EPS30010.1 - 5.5 7.2 14.6 20 5.4 14.6 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Com_YlbF PF06133.11 EPS30010.1 - 5.6 7.6 23.4 0.22 12.1 7.7 2.2 1 1 1 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA OmpH PF03938.14 EPS30010.1 - 6 7.2 27.6 7.1e+02 0.5 27.2 2.1 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4140 PF13600.6 EPS30010.1 - 6.1 7.4 12.3 3.6 8.1 3.5 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF1664 PF07889.12 EPS30010.1 - 6.5 6.8 12.7 7.7 6.6 3.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Allexi_40kDa PF05549.11 EPS30010.1 - 8.1 5.9 6.6 6.5 6.2 0.6 1.9 1 1 1 2 2 2 0 Allexivirus 40kDa protein FliD_N PF02465.18 EPS30010.1 - 9.7 7.0 15.9 16 6.3 4.9 2.9 1 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus iPGM_N PF06415.13 EPS30011.1 - 2.4e-76 255.9 0.0 3.7e-76 255.3 0.0 1.3 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Metalloenzyme PF01676.18 EPS30011.1 - 9.6e-68 228.2 0.0 1.1e-67 228.0 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 EPS30011.1 - 2.3e-07 30.7 0.0 3.6e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EPS30011.1 - 7.1e-05 22.3 0.0 0.00012 21.6 0.0 1.5 1 0 0 1 1 1 1 Sulfatase Alk_phosphatase PF00245.20 EPS30011.1 - 0.083 11.8 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Alkaline phosphatase Methyltransf_31 PF13847.6 EPS30011.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Med9 PF07544.13 EPS30012.1 - 2.1e-19 69.4 0.0 5e-19 68.2 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 Med21 PF11221.8 EPS30012.1 - 0.009 16.3 4.0 0.013 15.8 4.0 1.5 1 1 0 1 1 1 1 Subunit 21 of Mediator complex GP41 PF00517.17 EPS30012.1 - 0.018 15.0 0.1 0.025 14.5 0.1 1.2 1 0 0 1 1 1 0 Retroviral envelope protein DUF1843 PF08898.10 EPS30012.1 - 0.18 12.4 0.7 0.34 11.5 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) ATG16 PF08614.11 EPS30012.1 - 0.53 10.5 2.5 0.91 9.7 2.5 1.3 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) SHMT PF00464.19 EPS30013.1 - 4e-209 694.1 0.0 4.6e-209 693.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 EPS30013.1 - 3.4e-07 29.8 0.0 6.7e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EPS30013.1 - 0.0047 16.3 0.0 0.0074 15.6 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EPS30013.1 - 0.05 12.1 0.0 0.081 11.4 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme AMMECR1 PF01871.17 EPS30014.1 - 8.8e-41 139.3 0.0 1.4e-40 138.6 0.0 1.3 1 0 0 1 1 1 1 AMMECR1 PI3K_1B_p101 PF10486.9 EPS30014.1 - 0.51 8.0 1.9 0.66 7.7 1.9 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RAP1 PF07218.11 EPS30014.1 - 1.5 7.0 8.0 2.1 6.5 8.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pkinase PF00069.25 EPS30015.1 - 4.3e-73 245.9 0.0 5.4e-73 245.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS30015.1 - 2.7e-30 105.5 0.0 3.5e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EPS30015.1 - 1.4e-07 31.1 0.0 2e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EPS30015.1 - 6.5e-05 21.9 0.0 0.00011 21.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EPS30015.1 - 0.00012 21.5 0.0 0.00021 20.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EPS30015.1 - 0.00041 20.3 0.1 0.00067 19.7 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1744 PF08490.12 EPS30016.1 - 7.4e-151 502.3 0.0 1.2e-150 501.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 EPS30016.1 - 5.4e-83 278.9 0.5 9.3e-83 278.1 0.5 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 EPS30016.1 - 8.2e-15 54.4 0.2 4e-13 48.9 0.2 2.8 1 1 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 EPS30016.1 - 1.7e-08 34.4 0.0 4.6e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 EPS30016.1 - 3.9e-05 23.7 0.0 0.00016 21.7 0.0 2.1 1 0 0 1 1 1 1 RNase_H superfamily DUF3767 PF12597.8 EPS30017.1 - 3.4e-34 116.7 0.1 6.3e-34 115.8 0.0 1.4 1 1 1 2 2 2 1 Protein of unknown function (DUF3767) Jak1_Phl PF17887.1 EPS30017.1 - 0.13 12.3 1.3 0.21 11.6 1.3 1.3 1 0 0 1 1 1 0 Jak1 pleckstrin homology-like domain PBP-Tp47_c PF14888.6 EPS30019.1 - 0.084 12.8 0.3 0.15 12.0 0.3 1.4 1 1 0 1 1 1 0 Penicillin-binding protein Tp47 domain C Nop PF01798.18 EPS30020.1 - 1.5e-88 296.1 0.1 1.5e-88 296.1 0.1 1.7 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EPS30020.1 - 9.1e-19 67.6 0.1 9.1e-19 67.6 0.1 2.4 2 0 0 2 2 2 1 NOP5NT (NUC127) domain AAA_25 PF13481.6 EPS30020.1 - 0.095 12.3 0.3 0.19 11.3 0.3 1.4 1 0 0 1 1 1 0 AAA domain CDC45 PF02724.14 EPS30020.1 - 7.1 4.8 22.0 11 4.2 22.0 1.2 1 0 0 1 1 1 0 CDC45-like protein RNA_polI_A34 PF08208.11 EPS30020.1 - 8.2 6.5 34.6 15 5.6 34.6 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Cpn60_TCP1 PF00118.24 EPS30021.1 - 1.5e-161 538.4 0.7 1.7e-161 538.2 0.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family MOZ_SAS PF01853.18 EPS30022.1 - 2.8e-62 209.5 0.0 4.2e-62 209.0 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EPS30022.1 - 4.9e-17 61.3 1.2 9.5e-17 60.4 1.2 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain RRM_1 PF00076.22 EPS30023.1 - 2.2e-12 46.6 0.0 3.9e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Herpes_DNAp_acc PF04929.12 EPS30023.1 - 3.6 6.5 5.7 7.2 5.5 5.7 1.4 1 0 0 1 1 1 0 Herpes DNA replication accessory factor tRNA-synt_2 PF00152.20 EPS30024.1 - 4.6e-65 219.7 0.0 2.5e-64 217.3 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EPS30024.1 - 2.4e-06 27.4 0.0 3.8e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Gti1_Pac2 PF09729.9 EPS30028.1 - 2e-44 151.9 1.0 5.4e-37 127.6 0.1 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family DUF2442 PF10387.9 EPS30031.1 - 0.076 13.3 0.0 8.7 6.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2442) Fungal_trans_2 PF11951.8 EPS30032.1 - 1.6e-62 211.6 0.0 2.1e-62 211.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS30032.1 - 2.4e-09 37.2 10.4 3.7e-09 36.5 10.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2385 PF09539.10 EPS30032.1 - 0.064 13.8 0.0 24 5.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) AT_hook PF02178.19 EPS30032.1 - 0.41 10.7 6.8 1.2 9.2 6.8 1.9 1 0 0 1 1 1 0 AT hook motif HpcH_HpaI PF03328.14 EPS30033.1 - 9e-35 119.8 0.0 1.1e-34 119.5 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family ABC_tran PF00005.27 EPS30034.1 - 1e-51 175.0 0.0 2.1e-25 89.8 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 EPS30034.1 - 9.4e-51 172.2 29.9 7.6e-29 100.6 10.9 2.3 2 0 0 2 2 2 2 ABC-2 type transporter AAA_21 PF13304.6 EPS30034.1 - 8.2e-14 52.1 0.0 0.0095 15.8 0.0 4.4 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EPS30034.1 - 5.2e-10 40.0 0.1 0.0017 18.8 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EPS30034.1 - 2.4e-09 37.3 0.3 0.0029 17.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 EPS30034.1 - 3.1e-08 34.4 0.1 0.00055 20.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 EPS30034.1 - 4e-08 33.0 0.4 0.0029 17.1 0.1 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EPS30034.1 - 7.3e-07 28.8 1.2 0.038 13.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EPS30034.1 - 3e-06 27.5 0.1 0.03 14.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 EPS30034.1 - 4.5e-05 23.4 0.1 0.044 13.7 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_25 PF13481.6 EPS30034.1 - 4.8e-05 23.0 0.0 0.38 10.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EPS30034.1 - 0.00011 22.2 1.8 0.29 11.2 0.2 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase cobW PF02492.19 EPS30034.1 - 0.00013 21.6 0.5 0.19 11.3 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 EPS30034.1 - 0.00019 21.4 0.0 0.013 15.4 0.0 2.2 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 EPS30034.1 - 0.00043 20.1 0.1 0.5 10.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 EPS30034.1 - 0.00051 20.5 0.1 0.53 10.7 0.0 2.8 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EPS30034.1 - 0.00062 20.1 1.0 0.56 10.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 EPS30034.1 - 0.0007 18.7 0.2 0.035 13.2 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein RNA_helicase PF00910.22 EPS30034.1 - 0.0011 19.3 0.1 0.38 11.2 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_15 PF13175.6 EPS30034.1 - 0.0017 18.1 0.0 2.5 7.7 0.1 2.9 3 0 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.6 EPS30034.1 - 0.0018 18.5 0.1 0.74 10.0 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 EPS30034.1 - 0.0025 17.6 0.1 2.9 7.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 EPS30034.1 - 0.0026 17.8 0.2 0.4 10.7 0.0 2.7 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) Roc PF08477.13 EPS30034.1 - 0.004 17.4 0.2 3.9 7.7 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 EPS30034.1 - 0.0089 16.6 0.0 0.42 11.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EPS30034.1 - 0.011 16.1 0.1 5.6 7.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EPS30034.1 - 0.011 15.8 1.6 0.86 9.6 0.1 2.3 2 0 0 2 2 2 0 Dynamin family NTPase_1 PF03266.15 EPS30034.1 - 0.019 14.9 0.1 3 7.7 0.0 2.9 3 0 0 3 3 3 0 NTPase ATP_bind_1 PF03029.17 EPS30034.1 - 0.021 14.6 0.1 7.7 6.2 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DnaB_C PF03796.15 EPS30034.1 - 0.029 13.7 0.8 0.82 9.0 0.0 2.5 3 0 0 3 3 2 0 DnaB-like helicase C terminal domain PRK PF00485.18 EPS30034.1 - 0.043 13.6 1.1 8.6 6.0 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 EPS30034.1 - 0.046 13.0 0.6 6.7 5.9 0.3 2.3 2 0 0 2 2 2 0 Zeta toxin ATP-synt_ab PF00006.25 EPS30034.1 - 0.05 13.3 0.0 5.1 6.7 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain KAP_NTPase PF07693.14 EPS30034.1 - 0.056 12.7 0.0 3.6 6.7 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain MobB PF03205.14 EPS30034.1 - 0.06 13.3 0.2 14 5.6 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.9 EPS30034.1 - 0.075 12.8 0.5 8.2 6.2 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PhoH PF02562.16 EPS30034.1 - 0.079 12.4 0.1 9.8 5.6 0.1 2.3 2 0 0 2 2 2 0 PhoH-like protein FtsK_SpoIIIE PF01580.18 EPS30034.1 - 0.088 12.1 0.1 4.9 6.4 0.2 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family SRPRB PF09439.10 EPS30034.1 - 0.1 12.0 0.3 7.6 5.9 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 EPS30034.1 - 0.11 12.0 0.7 7.6 6.0 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Septin PF00735.18 EPS30034.1 - 0.14 11.4 0.2 9.9 5.3 0.0 2.3 2 0 0 2 2 2 0 Septin TsaE PF02367.17 EPS30034.1 - 0.15 12.0 0.1 12 5.9 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cytidylate_kin PF02224.18 EPS30034.1 - 0.24 11.1 2.9 0.97 9.1 0.0 2.5 3 0 0 3 3 2 0 Cytidylate kinase DUF2075 PF09848.9 EPS30034.1 - 0.25 10.5 0.2 3.7 6.7 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_35 PF14516.6 EPS30034.1 - 0.29 9.9 0.6 3 6.6 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain Pox_A32 PF04665.12 EPS30034.1 - 0.37 10.2 2.2 13 5.1 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein DUF2627 PF11118.8 EPS30034.1 - 7.7 7.2 8.7 4.8 7.8 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2627) Sec23_trunk PF04811.15 EPS30038.1 - 7.6e-52 176.3 0.0 2.9e-51 174.4 0.0 1.8 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EPS30038.1 - 1.8e-25 88.7 0.0 5e-25 87.3 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EPS30038.1 - 7e-18 65.2 0.0 1.3e-17 64.3 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EPS30038.1 - 1.7e-15 56.7 4.6 3.7e-15 55.7 4.6 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EPS30038.1 - 3.9e-09 36.3 0.0 7.5e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Gelsolin repeat DUF1678 PF07913.11 EPS30038.1 - 0.048 13.4 0.0 0.09 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1678) SLS PF14611.6 EPS30038.1 - 0.18 11.6 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial inner-membrane-bound regulator AA_permease_2 PF13520.6 EPS30039.1 - 7e-54 183.3 45.4 8.2e-54 183.0 45.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPS30039.1 - 5.4e-22 78.0 39.7 7.1e-22 77.6 39.7 1.0 1 0 0 1 1 1 1 Amino acid permease Peptidase_M56 PF05569.11 EPS30039.1 - 2.3 7.3 7.1 0.24 10.5 2.0 1.9 2 0 0 2 2 2 0 BlaR1 peptidase M56 Fungal_trans PF04082.18 EPS30040.1 - 4.7e-21 75.0 0.3 9.6e-21 74.0 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Big_9 PF17963.1 EPS30040.1 - 0.12 13.1 1.2 1.6 9.5 0.2 2.2 2 0 0 2 2 2 0 Bacterial Ig domain DUF2802 PF10975.8 EPS30040.1 - 0.16 12.1 4.8 0.48 10.6 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2802) Hydrolase PF00702.26 EPS30041.1 - 0.00042 20.7 0.0 0.0018 18.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EPS30041.1 - 0.0014 18.8 0.0 0.0019 18.3 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EPS30041.1 - 0.028 14.5 0.0 0.47 10.6 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase AA_permease PF00324.21 EPS30042.1 - 8.4e-100 334.6 47.1 1e-99 334.3 47.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EPS30042.1 - 3.3e-26 92.1 47.7 4.5e-26 91.6 47.7 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3392 PF11872.8 EPS30042.1 - 0.066 13.5 19.5 1.9 8.8 0.5 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3392) DAO PF01266.24 EPS30043.1 - 2.8e-47 162.0 0.3 3.3e-47 161.8 0.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EPS30043.1 - 5.3e-06 25.9 0.1 0.012 14.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EPS30043.1 - 1.7e-05 24.2 0.1 0.00047 19.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPS30043.1 - 3.1e-05 24.1 0.3 9.5e-05 22.6 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain MCRA PF06100.11 EPS30043.1 - 0.0001 21.3 0.1 0.00038 19.4 0.1 1.8 2 0 0 2 2 2 1 MCRA family HI0933_like PF03486.14 EPS30043.1 - 0.00037 19.3 0.3 0.48 9.1 0.0 2.1 1 1 1 2 2 2 2 HI0933-like protein NAD_binding_9 PF13454.6 EPS30043.1 - 0.00038 20.5 0.4 0.0099 15.9 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 EPS30043.1 - 0.00038 19.8 0.0 0.00083 18.7 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 EPS30043.1 - 0.011 16.3 0.2 1.1 9.8 0.1 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EPS30043.1 - 0.047 12.8 0.0 0.13 11.4 0.0 1.7 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 EPS30043.1 - 0.15 11.1 1.6 0.26 10.3 0.9 1.7 2 0 0 2 2 2 0 FAD binding domain Lactamase_B_6 PF16661.5 EPS30044.1 - 1.4e-65 220.4 0.0 2.6e-65 219.5 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 EPS30044.1 - 5.1e-46 157.0 0.0 5.1e-46 157.0 0.0 2.4 3 0 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.8 EPS30044.1 - 4.9e-15 55.8 0.0 2.3e-14 53.6 0.0 2.2 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.12 EPS30044.1 - 2.7e-10 40.0 0.1 8.7e-10 38.4 0.0 1.9 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 EPS30044.1 - 0.083 12.9 0.1 0.19 11.7 0.1 1.6 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily Frag1 PF10277.9 EPS30046.1 - 8.4e-41 139.9 7.4 8.4e-41 139.9 7.4 2.6 2 1 0 2 2 2 1 Frag1/DRAM/Sfk1 family U3_assoc_6 PF08640.11 EPS30047.1 - 2.9e-28 97.7 1.6 2.9e-28 97.7 1.6 1.8 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 EPS30047.1 - 0.00024 21.7 0.0 2.5 9.1 0.0 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat NRDE-2 PF08424.10 EPS30047.1 - 0.018 14.2 0.4 0.043 12.9 0.4 1.6 1 1 0 1 1 1 0 NRDE-2, necessary for RNA interference Suf PF05843.14 EPS30047.1 - 0.17 11.9 1.6 6.8 6.6 0.1 2.6 3 0 0 3 3 3 0 Suppressor of forked protein (Suf) RF-1 PF00472.20 EPS30048.1 - 1.1e-13 51.2 7.5 3e-13 49.7 7.5 1.6 1 1 0 1 1 1 1 RF-1 domain RRM_1 PF00076.22 EPS30049.1 - 3e-09 36.6 0.0 4.9e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EPS30049.1 - 2e-07 30.6 0.0 7.3e-07 28.8 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) COX6B PF02297.17 EPS30050.1 - 3e-23 81.8 4.5 4.1e-23 81.4 4.5 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 EPS30050.1 - 0.0056 17.0 0.9 0.011 16.0 0.9 1.5 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Prolamin_like PF05617.11 EPS30050.1 - 0.017 15.3 0.3 0.021 15.0 0.3 1.2 1 0 0 1 1 1 0 Prolamin-like UBA_2 PF08587.11 EPS30050.1 - 0.057 13.5 4.0 4 7.6 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) SYS1 PF09801.9 EPS30051.1 - 4.7e-53 179.2 7.0 5.5e-53 179.0 7.0 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DUF4199 PF13858.6 EPS30051.1 - 4.4 7.7 10.0 20 5.5 7.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) Amidase PF01425.21 EPS30052.1 - 7.3e-120 401.0 0.0 9.1e-120 400.7 0.0 1.1 1 0 0 1 1 1 1 Amidase Aldolase_II PF00596.21 EPS30053.1 - 5.1e-46 157.0 0.2 6.8e-46 156.6 0.2 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain COG5 PF10392.9 EPS30054.1 - 2.5e-39 134.5 0.3 2.5e-39 134.5 0.3 2.9 4 0 0 4 4 4 1 Golgi transport complex subunit 5 zf-C2H2 PF00096.26 EPS30056.1 - 1.2e-05 25.4 12.0 0.0046 17.4 1.8 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EPS30056.1 - 0.0003 21.1 3.8 0.0003 21.1 3.8 2.2 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EPS30056.1 - 0.001 19.7 11.3 0.081 13.8 2.9 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger TylF PF05711.11 EPS30056.1 - 0.27 10.5 0.0 0.43 9.8 0.0 1.2 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) zf-H2C2_5 PF13909.6 EPS30056.1 - 1.8 8.4 5.6 2.7 7.8 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Apolipoprotein PF01442.18 EPS30057.1 - 9.8e-05 22.3 4.0 0.00014 21.8 4.0 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 EPS30057.1 - 0.00053 20.5 4.7 0.0014 19.2 4.3 1.9 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF883) DUF5339 PF17274.2 EPS30057.1 - 0.11 13.4 0.4 0.11 13.4 0.4 1.9 2 1 0 2 2 2 0 Family of unknown function (DUF5339) PI3K_C2 PF00792.24 EPS30057.1 - 0.18 11.7 0.1 0.23 11.3 0.1 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 RRF PF01765.19 EPS30057.1 - 0.19 11.7 5.4 0.23 11.4 5.4 1.2 1 0 0 1 1 1 0 Ribosome recycling factor MT0933_antitox PF14013.6 EPS30057.1 - 1.3 9.4 9.8 0.98 9.8 1.7 2.6 2 1 0 2 2 2 0 MT0933-like antitoxin protein ATP-synt_B PF00430.18 EPS30057.1 - 2.2 8.4 8.7 3.2 7.8 8.7 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) CDT1_C PF16679.5 EPS30058.1 - 4.7e-23 81.5 0.0 1e-22 80.4 0.0 1.6 1 0 0 1 1 1 1 DNA replication factor Cdt1 C-terminal domain MutS_V PF00488.21 EPS30059.1 - 1.4e-81 273.0 0.6 4.3e-81 271.4 0.1 2.0 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 EPS30059.1 - 6.1e-39 134.2 0.5 6.1e-39 134.2 0.5 2.1 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 EPS30059.1 - 5.2e-17 62.4 0.5 3.2e-16 59.8 0.0 2.4 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 EPS30059.1 - 1.2e-16 60.8 0.6 1.2e-16 60.8 0.6 2.6 3 0 0 3 3 3 1 MutS family domain IV MutS_I PF01624.20 EPS30059.1 - 7e-16 58.5 0.0 6.8e-15 55.3 0.0 2.4 2 0 0 2 2 2 1 MutS domain I SUR7 PF06687.12 EPS30059.1 - 0.16 11.6 0.0 0.51 9.9 0.0 1.8 2 1 0 2 2 2 0 SUR7/PalI family Gpi1 PF05024.15 EPS30060.1 - 5e-78 261.5 9.0 9e-78 260.6 9.0 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) DAGK_prokar PF01219.19 EPS30060.1 - 0.22 11.4 0.1 0.22 11.4 0.1 2.1 2 0 0 2 2 2 0 Prokaryotic diacylglycerol kinase UPF0203 PF05254.12 EPS30061.1 - 1.4e-27 95.7 3.8 1.6e-27 95.5 3.8 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) COX17 PF05051.13 EPS30061.1 - 2.1e-05 24.8 1.5 4.5e-05 23.7 1.5 1.5 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 EPS30061.1 - 0.00015 21.7 3.2 0.027 14.5 0.1 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.16 EPS30061.1 - 0.009 16.2 2.2 0.019 15.2 2.2 1.5 1 1 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein DUF5339 PF17274.2 EPS30061.1 - 0.62 10.9 5.5 0.8 10.6 1.3 2.5 2 1 0 2 2 2 0 Family of unknown function (DUF5339) DNA_pol_A_exo1 PF01612.20 EPS30062.1 - 3.2e-39 134.4 0.3 5.1e-39 133.8 0.3 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 EPS30062.1 - 1.2e-28 99.6 0.4 2.7e-28 98.5 0.4 1.6 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.23 EPS30062.1 - 6e-12 45.4 0.3 1.5e-11 44.1 0.0 1.9 2 0 0 2 2 2 1 HRDC domain PGA2 PF07543.12 EPS30062.1 - 0.12 12.3 2.5 0.26 11.3 2.5 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 BCIP PF13862.6 EPS30062.1 - 0.14 11.9 3.5 0.32 10.8 0.0 2.6 3 0 0 3 3 3 0 p21-C-terminal region-binding protein tRNA-synt_1b PF00579.25 EPS30063.1 - 4.6e-16 59.0 0.0 1.5e-15 57.3 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Aminotran_4 PF01063.19 EPS30064.1 - 6e-33 114.6 0.0 7.4e-33 114.3 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV TPR_1 PF00515.28 EPS30065.1 - 2.4e-39 131.6 23.3 6.8e-07 28.8 0.0 11.6 10 1 1 11 11 11 8 Tetratricopeptide repeat TPR_2 PF07719.17 EPS30065.1 - 2.5e-36 120.8 24.9 2.8e-05 23.9 0.0 11.2 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_16 PF13432.6 EPS30065.1 - 1.3e-23 83.3 18.7 5.6e-06 26.9 0.2 7.8 7 2 1 9 9 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 EPS30065.1 - 3.6e-20 70.4 18.5 0.00042 20.3 0.0 9.6 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.6 EPS30065.1 - 4.7e-20 71.0 21.2 1.8e-06 27.5 0.0 8.8 6 1 2 8 8 8 5 TPR repeat TPR_17 PF13431.6 EPS30065.1 - 6.9e-19 66.8 2.1 0.026 14.9 0.0 8.0 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 EPS30065.1 - 3.7e-15 55.8 12.9 1.5e-05 25.0 0.1 6.0 4 1 3 7 7 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 EPS30065.1 - 5.6e-14 52.4 23.4 2.4e-05 24.7 0.9 6.8 6 1 0 7 7 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 EPS30065.1 - 3e-13 49.8 32.0 0.00064 20.0 2.6 8.8 4 3 4 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 EPS30065.1 - 1.7e-12 47.0 19.4 0.0058 17.3 0.1 9.0 5 3 5 10 10 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 EPS30065.1 - 1.5e-11 43.4 20.2 0.029 14.4 0.2 8.5 7 1 1 8 8 8 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EPS30065.1 - 6.6e-08 32.7 13.3 0.024 14.8 0.6 5.5 2 2 3 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 EPS30065.1 - 2.6e-07 30.3 19.6 0.23 11.4 0.4 8.6 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EPS30065.1 - 0.00013 21.4 4.4 0.00058 19.3 3.3 2.5 1 1 0 1 1 1 1 MalT-like TPR region SHNi-TPR PF10516.9 EPS30065.1 - 0.00039 19.8 9.4 0.36 10.3 0.1 4.9 5 0 0 5 5 4 2 SHNi-TPR TPR_6 PF13174.6 EPS30065.1 - 0.004 17.7 24.1 6.7 7.6 0.0 9.0 11 0 0 11 11 9 0 Tetratricopeptide repeat AP3D1 PF06375.11 EPS30065.1 - 0.005 17.1 5.2 0.01 16.1 5.2 1.5 1 0 0 1 1 1 1 AP-3 complex subunit delta-1 Sigma70_ner PF04546.13 EPS30065.1 - 0.014 15.3 3.0 0.049 13.5 3.0 1.9 1 0 0 1 1 1 0 Sigma-70, non-essential region MAS20 PF02064.15 EPS30065.1 - 0.03 14.4 10.6 0.21 11.7 1.3 4.2 4 1 1 5 5 4 0 MAS20 protein import receptor PPP4R2 PF09184.11 EPS30065.1 - 0.077 12.6 7.2 1.8 8.1 3.3 2.4 3 0 0 3 3 2 0 PPP4R2 DDHD PF02862.17 EPS30065.1 - 0.11 12.6 1.1 0.24 11.5 1.1 1.6 1 0 0 1 1 1 0 DDHD domain GPCR_chapero_1 PF11904.8 EPS30065.1 - 0.14 11.5 4.3 0.27 10.6 4.3 1.4 1 0 0 1 1 1 0 GPCR-chaperone RNA_pol_Rpc4 PF05132.14 EPS30065.1 - 0.16 12.4 4.0 0.35 11.3 4.0 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Sel1 PF08238.12 EPS30065.1 - 0.16 12.7 6.1 0.9 10.3 0.2 4.2 4 0 0 4 4 3 0 Sel1 repeat NARP1 PF12569.8 EPS30065.1 - 0.35 9.7 25.1 0.46 9.3 0.1 4.8 3 1 0 4 4 4 0 NMDA receptor-regulated protein 1 ANAPC5 PF12862.7 EPS30065.1 - 0.59 10.2 10.5 13 5.9 0.1 4.7 3 2 1 4 4 3 0 Anaphase-promoting complex subunit 5 NPR3 PF03666.13 EPS30065.1 - 0.7 8.6 5.8 0.13 11.1 2.1 1.5 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF1682 PF07946.14 EPS30065.1 - 0.71 9.0 7.6 1.3 8.1 7.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) STAC2_u1 PF16664.5 EPS30065.1 - 0.98 9.9 8.2 2.2 8.8 8.2 1.5 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 BCIP PF13862.6 EPS30065.1 - 4 7.2 6.8 2.9 7.6 0.0 2.5 2 0 0 2 2 2 0 p21-C-terminal region-binding protein FHA PF00498.26 EPS30066.1 - 8.9e-12 45.2 0.0 1.8e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EPS30066.1 - 0.0086 16.4 0.0 0.019 15.3 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain TSGA13 PF14994.6 EPS30066.1 - 0.14 11.5 0.2 0.25 10.7 0.2 1.3 1 0 0 1 1 1 0 Testis-specific gene 13 protein GCIP PF13324.6 EPS30066.1 - 1.8 8.1 6.2 3.9 7.0 6.2 1.5 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting SDA1 PF05285.12 EPS30066.1 - 8 5.8 15.9 2.1 7.7 10.0 2.2 2 1 0 2 2 2 0 SDA1 MFS_1 PF07690.16 EPS30067.1 - 3.5e-34 118.3 24.5 5.7e-34 117.6 24.5 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EPS30067.1 - 3.7e-05 22.4 3.0 6e-05 21.7 3.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.6 EPS30067.1 - 0.00029 19.5 5.5 0.00029 19.5 5.5 3.7 2 2 1 3 3 3 2 MFS/sugar transport protein FAD_binding_3 PF01494.19 EPS30069.1 - 1.1e-20 74.2 0.0 5.4e-20 71.9 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EPS30069.1 - 1.4e-08 34.8 5.1 0.00035 20.3 0.0 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPS30069.1 - 1.7e-07 30.8 1.7 0.0026 17.0 1.0 2.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPS30069.1 - 5.8e-06 26.8 0.8 0.014 16.0 0.4 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EPS30069.1 - 2.6e-05 23.1 2.3 0.0037 16.0 2.5 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 EPS30069.1 - 3.7e-05 23.0 1.0 5.9e-05 22.3 1.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EPS30069.1 - 0.00026 21.2 0.6 0.0008 19.6 0.6 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EPS30069.1 - 0.00039 19.9 3.2 0.00062 19.2 3.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 EPS30069.1 - 0.00046 19.4 0.1 0.00058 19.0 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 EPS30069.1 - 0.0013 17.7 1.2 0.0016 17.4 0.2 1.5 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_3 PF13738.6 EPS30069.1 - 0.011 15.0 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EPS30069.1 - 0.021 13.9 0.0 0.25 10.4 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase 3HCDH_N PF02737.18 EPS30069.1 - 0.05 13.5 0.1 0.081 12.8 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.17 EPS30069.1 - 0.14 11.3 0.8 0.22 10.7 0.8 1.2 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 EPS30069.1 - 0.26 10.5 1.3 0.43 9.8 1.3 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GST_N_3 PF13417.6 EPS30070.1 - 8.8e-09 35.7 0.0 1.5e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EPS30070.1 - 9.6e-09 35.5 0.0 4.4e-08 33.3 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EPS30070.1 - 2.6e-07 30.9 0.0 5e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EPS30070.1 - 5.1e-07 29.8 0.0 1.2e-06 28.6 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EPS30070.1 - 1.5e-06 28.3 0.0 2.6e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EPS30070.1 - 0.00095 19.1 0.1 0.0023 17.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EPS30070.1 - 0.13 12.8 0.0 0.26 11.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Fungal_trans PF04082.18 EPS30071.1 - 1.6e-13 50.3 3.3 1.7e-13 50.2 0.7 2.2 2 1 1 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS30071.1 - 1.9e-09 37.5 12.7 3.5e-09 36.7 12.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tmemb_cc2 PF10267.9 EPS30071.1 - 0.05 12.7 0.1 0.075 12.2 0.1 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Cupin_2 PF07883.11 EPS30072.1 - 1.8e-14 53.2 0.6 1.1e-07 31.5 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 EPS30072.1 - 0.00015 21.4 0.2 0.015 15.0 0.1 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF861) Cupin_1 PF00190.22 EPS30072.1 - 0.0071 16.0 0.3 3.1 7.4 0.1 2.4 2 0 0 2 2 2 2 Cupin AraC_binding PF02311.19 EPS30072.1 - 0.015 15.2 0.1 0.71 9.8 0.1 2.3 2 0 0 2 2 2 0 AraC-like ligand binding domain cNMP_binding PF00027.29 EPS30072.1 - 0.016 15.3 0.0 3.3 7.9 0.0 3.0 2 1 1 3 3 3 0 Cyclic nucleotide-binding domain Cupin_4 PF08007.12 EPS30072.1 - 0.1 12.0 0.4 0.33 10.4 0.1 1.8 2 0 0 2 2 2 0 Cupin superfamily protein EutQ PF06249.12 EPS30072.1 - 0.1 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ MannoseP_isomer PF01050.18 EPS30072.1 - 0.13 12.2 0.0 7.2 6.5 0.0 2.2 2 0 0 2 2 2 0 Mannose-6-phosphate isomerase DUF3500 PF12006.8 EPS30073.1 - 6.8e-113 377.1 0.0 8.7e-113 376.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) L_HMGIC_fpl PF10242.9 EPS30074.1 - 3.6e-05 24.0 4.9 7.5e-05 23.0 4.9 1.5 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein ABC2_membrane PF01061.24 EPS30074.1 - 0.042 13.3 4.5 0.091 12.2 2.3 2.0 2 0 0 2 2 2 0 ABC-2 type transporter DUF4405 PF14358.6 EPS30074.1 - 0.081 13.5 4.3 3.8 8.1 0.1 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4405) SPC12 PF06645.13 EPS30074.1 - 0.2 11.8 0.2 0.2 11.8 0.2 3.1 4 0 0 4 4 4 0 Microsomal signal peptidase 12 kDa subunit (SPC12) RRM_1 PF00076.22 EPS30075.1 - 3e-47 158.3 0.0 1.9e-12 46.8 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EPS30075.1 - 5.8e-37 125.4 0.0 8.5e-31 105.6 0.0 4.1 4 0 0 4 4 4 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EPS30075.1 - 2.5e-07 30.6 0.0 0.6 10.1 0.0 4.0 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif Lsm_interact PF05391.11 EPS30075.1 - 0.019 14.5 0.1 0.054 13.0 0.1 1.8 1 0 0 1 1 1 0 Lsm interaction motif Nup35_RRM PF05172.13 EPS30075.1 - 0.019 14.9 0.0 0.19 11.7 0.0 2.6 2 1 1 3 3 3 0 Nup53/35/40-type RNA recognition motif SET PF00856.28 EPS30075.1 - 0.2 12.0 1.4 1.2 9.5 0.2 2.6 2 0 0 2 2 2 0 SET domain NST1 PF13945.6 EPS30075.1 - 6.6 6.8 17.7 5 7.2 3.1 2.4 2 0 0 2 2 2 0 Salt tolerance down-regulator Ribosomal_L22 PF00237.19 EPS30076.1 - 3e-30 104.5 0.0 6.4e-30 103.4 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e His_Phos_1 PF00300.22 EPS30077.1 - 1.2e-11 44.7 0.4 7.5e-11 42.1 0.4 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) GST_N_3 PF13417.6 EPS30079.1 - 9.2e-15 54.8 0.0 1.9e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EPS30079.1 - 5.6e-14 52.2 0.0 1.1e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EPS30079.1 - 5.1e-12 45.9 0.0 1.2e-11 44.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EPS30079.1 - 2e-11 44.0 0.0 3.8e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EPS30079.1 - 3.2e-11 43.3 0.0 5.2e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EPS30079.1 - 9.7e-09 35.1 0.6 1.5e-08 34.5 0.1 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EPS30079.1 - 0.15 11.9 0.0 0.35 10.7 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SF1-HH PF16275.5 EPS30080.1 - 6.9e-44 148.8 1.6 1.8e-43 147.5 1.6 1.7 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain zf-CCHC PF00098.23 EPS30080.1 - 6.7e-12 44.9 11.1 1.3e-05 25.0 0.8 2.3 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.29 EPS30080.1 - 6.5e-08 32.3 0.1 1.2e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.6 EPS30080.1 - 9.7e-07 28.6 5.3 0.0013 18.6 2.8 2.6 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.6 EPS30080.1 - 0.00098 18.9 6.4 0.35 10.7 0.5 2.8 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 EPS30080.1 - 0.0014 18.3 5.0 0.42 10.4 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.6 EPS30080.1 - 0.014 15.2 0.5 0.014 15.2 0.5 2.4 2 0 0 2 2 2 0 Zinc knuckle eIF3g PF12353.8 EPS30080.1 - 0.46 10.9 7.1 5.6 7.4 0.4 3.3 2 1 1 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G HCO3_cotransp PF00955.21 EPS30081.1 - 6.7e-84 282.5 11.2 1.6e-46 159.2 4.9 2.2 1 1 1 2 2 2 2 HCO3- transporter family RSRP PF17069.5 EPS30081.1 - 0.59 9.7 17.5 0.88 9.1 17.5 1.1 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 TMEM171 PF15471.6 EPS30081.1 - 5.5 5.9 6.7 8.4 5.3 6.7 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 DEAD PF00270.29 EPS30082.1 - 8.5e-42 142.9 0.0 2.1e-41 141.6 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPS30082.1 - 7.6e-30 103.5 0.0 3.3e-29 101.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPS30082.1 - 8.6e-07 29.1 0.0 1.6e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 EPS30082.1 - 0.019 14.7 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 SWI2/SNF2 ATPase SNF2_N PF00176.23 EPS30082.1 - 0.05 12.3 0.0 0.075 11.7 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain DUF1793 PF08760.11 EPS30084.1 - 3.6e-70 235.7 0.1 3.6e-70 235.7 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) DUF4965 PF16335.5 EPS30084.1 - 1.8e-63 213.3 2.4 1.7e-50 171.1 0.0 2.7 3 0 0 3 3 3 2 Domain of unknown function (DUF4965) DUF5127 PF17168.4 EPS30084.1 - 2.3e-45 155.1 0.0 4.7e-45 154.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5127) Glyco_hydr_116N PF12215.8 EPS30084.1 - 0.01 15.3 0.0 0.026 14.0 0.0 1.5 1 1 0 1 1 1 0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term DUF4964 PF16334.5 EPS30084.1 - 0.017 14.7 0.1 0.042 13.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4964) Arf PF00025.21 EPS30084.1 - 0.16 11.4 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family Stm1_N PF09598.10 EPS30085.1 - 8.7e-17 61.7 5.9 8.7e-17 61.7 5.9 5.7 4 1 0 4 4 4 1 Stm1 bZIP_1 PF00170.21 EPS30086.1 - 3.8e-05 23.7 9.5 7.6e-05 22.7 9.5 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EPS30086.1 - 0.0052 16.8 9.8 0.015 15.4 9.8 1.8 1 0 0 1 1 1 1 Basic region leucine zipper DUF4407 PF14362.6 EPS30086.1 - 0.043 13.2 2.6 0.51 9.6 3.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 EPS30086.1 - 0.052 13.7 2.0 0.083 13.1 2.0 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Pex19 PF04614.12 EPS30087.1 - 6e-74 248.9 1.1 7.5e-74 248.6 1.1 1.1 1 0 0 1 1 1 1 Pex19 protein family Toprim_C_rpt PF13368.6 EPS30087.1 - 0.048 13.7 0.0 0.096 12.7 0.0 1.5 1 0 0 1 1 1 0 Topoisomerase C-terminal repeat T2SSF PF00482.23 EPS30087.1 - 0.13 12.3 0.1 0.48 10.4 0.1 2.0 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F RecX PF02631.16 EPS30087.1 - 0.16 12.4 0.2 18 5.8 0.1 2.6 3 0 0 3 3 3 0 RecX family Isochorismatase PF00857.20 EPS30089.1 - 1.6e-36 126.1 0.1 1.9e-36 125.9 0.1 1.0 1 0 0 1 1 1 1 Isochorismatase family Mid2 PF04478.12 EPS30090.1 - 2.7e-09 37.0 0.4 2.7e-09 37.0 0.4 2.7 1 1 2 4 4 4 1 Mid2 like cell wall stress sensor Ndc1_Nup PF09531.10 EPS30090.1 - 0.013 14.2 8.0 0.014 14.1 8.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Endomucin PF07010.12 EPS30090.1 - 0.069 13.1 34.5 0.086 12.8 34.5 1.1 1 0 0 1 1 1 0 Endomucin ORC6 PF05460.13 EPS30090.1 - 0.16 11.2 12.0 0.18 11.0 12.0 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) TFIIA PF03153.13 EPS30090.1 - 0.17 11.8 4.5 0.2 11.6 4.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase_fungal PF17667.1 EPS30090.1 - 0.26 10.0 0.7 0.34 9.6 0.7 1.1 1 0 0 1 1 1 0 Fungal protein kinase GCOM2 PF15328.6 EPS30090.1 - 0.34 11.2 8.9 0.49 10.7 8.9 1.3 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 Apt1 PF10351.9 EPS30090.1 - 4 6.2 6.1 4.4 6.1 6.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Mrx7 PF10906.8 EPS30092.1 - 1.5e-10 41.2 0.1 3.1e-10 40.1 0.1 1.6 1 1 0 1 1 1 1 MIOREX complex component 7 Fungal_trans_2 PF11951.8 EPS30093.1 - 4.8e-28 98.0 1.4 2.2e-27 95.9 1.4 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS30093.1 - 1.7e-06 28.0 8.0 3.3e-06 27.1 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 EPS30094.1 - 5.1e-66 222.7 0.0 6.7e-66 222.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS30094.1 - 3.4e-31 108.5 0.0 3.4e-30 105.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 EPS30094.1 - 0.00064 19.4 0.1 0.21 11.2 0.0 2.3 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EPS30094.1 - 0.00065 19.1 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EPS30094.1 - 0.0025 17.2 0.0 0.012 14.9 0.0 2.0 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EPS30094.1 - 0.0064 15.5 0.1 0.011 14.8 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EPS30094.1 - 0.071 12.7 0.1 0.18 11.4 0.1 1.6 1 1 0 1 1 1 0 RIO1 family APH PF01636.23 EPS30094.1 - 0.098 12.6 0.1 0.24 11.3 0.1 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family ANAPC_CDC26 PF10471.9 EPS30095.1 - 7.2e-05 23.5 2.8 7.4e-05 23.5 1.3 1.9 2 1 0 2 2 2 1 Anaphase-promoting complex APC subunit CDC26 NAD_binding_8 PF13450.6 EPS30096.1 - 8e-09 35.6 0.0 1.8e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EPS30096.1 - 3.4e-06 26.6 0.0 6e-06 25.8 0.0 1.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 EPS30096.1 - 0.0015 17.8 0.3 0.019 14.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EPS30096.1 - 0.0049 16.2 0.1 0.0085 15.4 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EPS30096.1 - 0.0058 15.9 0.1 0.012 14.9 0.1 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 EPS30096.1 - 0.0076 15.5 0.1 0.012 14.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EPS30096.1 - 0.018 14.4 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF1344 PF07076.11 EPS30096.1 - 0.024 14.5 0.2 0.25 11.3 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1344) DAO PF01266.24 EPS30096.1 - 0.039 13.5 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EPS30096.1 - 0.051 12.3 0.0 0.078 11.7 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein TrkA_N PF02254.18 EPS30096.1 - 0.063 13.5 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Lycopene_cycl PF05834.12 EPS30096.1 - 0.074 12.1 0.3 0.17 10.9 0.1 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.6 EPS30096.1 - 0.15 12.1 0.3 0.81 9.7 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding TPT PF03151.16 EPS30098.1 - 1.9e-23 83.2 26.9 2.5e-23 82.8 26.9 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 EPS30098.1 - 0.084 12.1 27.5 0.18 11.0 27.5 1.5 1 1 0 1 1 1 0 UAA transporter family TFIIB PF00382.19 EPS30100.1 - 3.4e-31 107.1 0.4 2.7e-16 59.4 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 EPS30100.1 - 7e-27 93.7 0.3 2e-26 92.2 0.1 1.9 2 0 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 EPS30100.1 - 0.0001 21.7 2.3 0.00024 20.5 2.3 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 EPS30100.1 - 0.032 14.0 0.0 3.5 7.4 0.0 2.3 2 0 0 2 2 2 0 Cyclin, N-terminal domain DUF3667 PF12412.8 EPS30100.1 - 0.17 11.4 0.0 1.2 8.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3667) IBR PF01485.21 EPS30100.1 - 0.4 10.9 1.1 0.82 10.0 1.1 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain E1-E2_ATPase PF00122.20 EPS30101.1 - 8e-51 172.1 0.4 2.9e-50 170.3 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EPS30101.1 - 4.8e-34 118.5 0.0 1.4e-33 117.0 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EPS30101.1 - 2.5e-30 104.7 1.7 6.9e-13 48.8 0.1 3.6 3 0 0 3 3 3 3 Heavy-metal-associated domain Hydrolase_3 PF08282.12 EPS30101.1 - 2.5e-08 34.0 0.1 0.0011 18.8 0.1 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EPS30101.1 - 0.0011 19.4 0.0 0.0043 17.5 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CmcI PF04989.12 EPS30101.1 - 0.0081 15.9 0.0 0.043 13.5 0.0 2.1 2 0 0 2 2 2 1 Cephalosporin hydroxylase DUF2336 PF10098.9 EPS30101.1 - 0.028 13.9 0.1 4 6.8 0.0 2.7 3 0 0 3 3 3 0 Uncharacterised protein conserved in bacteria (DUF2336) DUF4052 PF13261.6 EPS30101.1 - 0.044 13.6 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4052) Hydrolase_6 PF13344.6 EPS30101.1 - 0.13 12.4 0.0 0.52 10.5 0.0 2.0 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF4231 PF14015.6 EPS30101.1 - 0.18 12.3 6.1 3.3 8.2 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) ERCC4 PF02732.15 EPS30102.1 - 3.5e-24 85.8 0.0 5.8e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain DUF4364 PF14277.6 EPS30102.1 - 0.0027 17.5 0.0 0.0055 16.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) Epimerase PF01370.21 EPS30103.1 - 1.4e-20 73.8 0.0 1.7e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EPS30103.1 - 2.4e-14 53.5 0.0 6e-14 52.2 0.0 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EPS30103.1 - 3.2e-13 49.3 0.0 3.9e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EPS30103.1 - 1.1e-06 28.0 0.1 0.048 12.8 0.0 2.6 1 1 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 EPS30103.1 - 2.7e-06 26.7 0.0 5.4e-06 25.7 0.0 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EPS30103.1 - 7.6e-05 22.7 0.0 0.00011 22.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EPS30103.1 - 0.0023 17.1 0.0 0.006 15.8 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 EPS30103.1 - 0.0075 16.2 0.1 2.2 8.1 0.1 2.3 1 1 0 2 2 2 2 KR domain Ldh_1_N PF00056.23 EPS30103.1 - 0.014 15.5 0.0 0.021 14.9 0.0 1.4 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain adh_short PF00106.25 EPS30103.1 - 0.097 12.1 0.0 0.21 11.0 0.0 1.7 2 1 0 2 2 2 0 short chain dehydrogenase Zn_clus PF00172.18 EPS30104.1 - 3.3e-06 27.1 10.6 5.3e-06 26.5 10.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPS30104.1 - 6.9e-06 25.3 0.5 1.3e-05 24.4 0.2 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain ChAPs PF09295.10 EPS30106.1 - 8.4e-155 515.6 0.0 1.1e-154 515.2 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_1 PF00515.28 EPS30106.1 - 5.2e-05 22.9 0.2 2.1 8.3 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EPS30106.1 - 7.3e-05 22.6 0.8 0.15 12.2 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EPS30106.1 - 0.00011 22.7 0.1 0.1 13.1 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EPS30106.1 - 0.00044 20.9 4.0 0.81 10.7 0.1 4.2 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 EPS30106.1 - 0.0057 15.9 2.5 0.46 9.6 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EPS30106.1 - 0.006 16.9 2.4 3.6 8.0 0.3 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EPS30106.1 - 0.014 15.4 1.5 11 6.3 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EPS30106.1 - 0.022 14.9 0.1 11 6.5 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 EPS30107.1 - 0.32 10.7 5.6 3.1 7.5 2.6 3.0 3 0 0 3 3 3 0 TPR repeat Kinesin PF00225.23 EPS30108.1 - 2.9e-61 207.2 0.0 4.2e-61 206.7 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EPS30108.1 - 9.3e-15 54.9 0.0 2.5e-12 47.0 0.0 2.4 2 0 0 2 2 2 2 Microtubule binding PspA_IM30 PF04012.12 EPS30108.1 - 0.014 15.0 3.2 1.1 8.8 0.1 2.3 2 0 0 2 2 2 0 PspA/IM30 family CCDC144C PF14915.6 EPS30108.1 - 0.014 14.5 1.4 3.5 6.6 0.2 2.2 2 0 0 2 2 2 0 CCDC144C protein coiled-coil region CENP-F_leu_zip PF10473.9 EPS30108.1 - 0.022 14.8 6.4 0.22 11.6 0.2 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cnn_1N PF07989.11 EPS30108.1 - 0.063 13.4 1.2 0.23 11.6 0.1 2.2 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 bZIP_2 PF07716.15 EPS30108.1 - 0.063 13.4 4.8 0.055 13.6 2.5 2.2 2 0 0 2 2 2 0 Basic region leucine zipper EzrA PF06160.12 EPS30108.1 - 0.83 7.8 5.3 6.1 4.9 0.5 2.2 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA CENP-H PF05837.12 EPS30108.1 - 1.8 9.0 6.7 10 6.5 0.3 2.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Ax_dynein_light PF10211.9 EPS30108.1 - 5.4 6.9 9.8 1.3 8.9 0.6 2.2 1 1 1 2 2 2 0 Axonemal dynein light chain GAS PF13851.6 EPS30108.1 - 8.5 5.7 8.1 3.7 6.8 1.6 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding MFS_1 PF07690.16 EPS30109.1 - 3.4e-33 115.0 26.0 3.4e-33 115.0 26.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS30109.1 - 7.1e-17 61.4 8.8 7.1e-17 61.4 8.8 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter DUF5463 PF17551.2 EPS30109.1 - 0.042 13.8 0.0 0.042 13.8 0.0 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5463) DUF5489 PF17592.2 EPS30109.1 - 0.54 10.8 6.9 0.13 12.8 1.7 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5489) Peptidase_S24 PF00717.23 EPS30110.1 - 6.5e-08 32.4 0.1 1.2e-07 31.6 0.1 1.5 1 1 0 1 1 1 1 Peptidase S24-like UQ_con PF00179.26 EPS30111.1 - 1.2e-40 138.4 0.0 1.4e-40 138.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EPS30111.1 - 6.3e-05 22.7 0.0 0.00011 21.9 0.0 1.4 1 1 0 1 1 1 1 Prokaryotic E2 family B RabGAP-TBC PF00566.18 EPS30113.1 - 6.6e-37 127.2 0.0 1.7e-36 125.9 0.0 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Peptidase_M64 PF09471.10 EPS30113.1 - 0.099 12.2 0.1 0.18 11.3 0.1 1.4 1 0 0 1 1 1 0 IgA Peptidase M64 Choline_transpo PF04515.12 EPS30114.1 - 2.8e-80 270.0 26.2 2.8e-80 270.0 26.2 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter WRW PF10206.9 EPS30114.1 - 0.073 13.4 3.3 0.37 11.2 3.3 2.2 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f CFEM PF05730.11 EPS30115.1 - 0.12 12.5 10.2 0.099 12.7 7.2 2.1 2 0 0 2 2 2 0 CFEM domain Pkinase PF00069.25 EPS30116.1 - 4.3e-23 82.0 0.0 9.3e-15 54.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EPS30116.1 - 1e-08 34.8 0.0 3.5e-06 26.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase BCS1_N PF08740.11 EPS30118.1 - 1.8e-49 168.3 0.6 2.5e-49 167.8 0.6 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EPS30118.1 - 4.8e-18 65.9 0.0 9.5e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EPS30118.1 - 2.7e-05 24.6 0.2 0.00021 21.7 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 EPS30118.1 - 0.00047 19.4 0.0 0.00082 18.6 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 EPS30118.1 - 0.0084 16.1 0.0 0.024 14.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EPS30118.1 - 0.0087 15.6 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 EPS30118.1 - 0.011 16.3 0.0 0.023 15.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EPS30118.1 - 0.013 15.9 0.0 0.047 14.1 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_25 PF13481.6 EPS30118.1 - 0.013 15.1 0.0 0.29 10.7 0.0 2.7 2 1 1 3 3 3 0 AAA domain ABC_tran PF00005.27 EPS30118.1 - 0.013 16.0 0.0 0.043 14.3 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_21 PF13304.6 EPS30118.1 - 0.014 15.3 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_24 PF13479.6 EPS30118.1 - 0.014 15.1 0.0 0.071 12.8 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.6 EPS30118.1 - 0.021 14.6 0.0 0.055 13.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EPS30118.1 - 0.025 14.9 0.0 0.086 13.1 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EPS30118.1 - 0.041 14.0 0.0 0.12 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain ATPase PF06745.13 EPS30118.1 - 0.069 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 KaiC MMR_HSR1 PF01926.23 EPS30118.1 - 0.083 13.0 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_11 PF13086.6 EPS30118.1 - 0.1 12.3 0.0 0.34 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EPS30118.1 - 0.11 12.4 0.0 0.42 10.5 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase PPV_E1_C PF00519.17 EPS30118.1 - 0.12 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase RuvB_N PF05496.12 EPS30118.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Lactamase_B_2 PF12706.7 EPS30119.1 - 1.3e-30 106.4 0.1 1.6e-29 102.9 0.1 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EPS30119.1 - 3.3e-10 40.1 0.0 2.4e-09 37.3 0.0 2.1 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EPS30119.1 - 2.8e-05 24.2 4.0 0.0069 16.4 0.7 3.1 2 2 0 2 2 2 2 Metallo-beta-lactamase superfamily Cpn60_TCP1 PF00118.24 EPS30120.1 - 1.3e-173 578.2 0.4 1.5e-173 578.0 0.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1168 PF06658.12 EPS30121.1 - 3.8e-39 133.6 9.0 5.8e-39 133.0 9.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) Lyase_catalyt PF09093.11 EPS30121.1 - 0.045 12.9 0.0 0.064 12.4 0.0 1.1 1 0 0 1 1 1 0 Lyase, catalytic RR_TM4-6 PF06459.12 EPS30121.1 - 1.6 8.5 6.7 1.8 8.3 6.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Presenilin PF01080.17 EPS30121.1 - 6 5.5 4.1 5.9 5.5 4.1 1.1 1 0 0 1 1 1 0 Presenilin Peptidase_S49_N PF08496.10 EPS30121.1 - 6.3 6.8 6.2 11 6.1 6.2 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal zf-PARP PF00645.18 EPS30122.1 - 1.2e-21 77.3 0.7 1.2e-21 77.3 0.7 2.2 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DUF3712 PF12505.8 EPS30123.1 - 0.0042 17.3 0.1 0.015 15.5 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3712) BTB PF00651.31 EPS30125.1 - 4.7e-06 26.8 0.0 1.2e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain B3_4 PF03483.17 EPS30125.1 - 0.056 13.1 0.1 8.4 6.0 0.0 2.2 2 0 0 2 2 2 0 B3/4 domain BT1 PF03092.16 EPS30126.1 - 0.0014 16.9 0.0 0.0021 16.4 0.0 1.2 1 0 0 1 1 1 1 BT1 family DUF2852 PF11014.8 EPS30126.1 - 0.11 12.6 0.0 2.1 8.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) SHS2_FTSA PF02491.20 EPS30126.1 - 0.12 12.7 0.1 0.29 11.5 0.1 1.6 1 0 0 1 1 1 0 SHS2 domain inserted in FTSA DUF2752 PF10825.8 EPS30126.1 - 1.2 9.3 3.8 1.9 8.6 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) CRF1 PF10380.9 EPS30128.1 - 0.021 15.2 0.2 0.021 15.2 0.2 2.4 2 1 1 3 3 3 0 Transcription factor CRF1 Pkinase PF00069.25 EPS30129.1 - 0.00023 20.6 0.0 0.00052 19.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS30129.1 - 0.00031 20.1 0.4 0.0039 16.5 0.4 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Glyco_hydro_18 PF00704.28 EPS30131.1 - 1.6e-48 166.1 0.0 1.6e-48 166.1 0.0 2.2 2 1 0 2 2 2 1 Glycosyl hydrolases family 18 LysM PF01476.20 EPS30131.1 - 7.4e-10 38.7 0.0 0.00036 20.5 0.0 2.8 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.19 EPS30131.1 - 6.1e-05 23.4 10.6 6.1e-05 23.4 10.6 3.4 3 1 0 3 3 3 1 Chitin recognition protein CFEM PF05730.11 EPS30132.1 - 0.00037 20.5 5.5 0.00037 20.5 5.5 2.8 2 0 0 2 2 2 1 CFEM domain Tme5_EGF_like PF09064.10 EPS30132.1 - 0.13 12.2 1.9 0.48 10.3 1.9 2.0 1 0 0 1 1 1 0 Thrombomodulin like fifth domain, EGF-like Pkinase PF00069.25 EPS30133.1 - 2.3e-09 37.0 0.0 5.8e-08 32.4 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS30133.1 - 1.7e-06 27.6 0.0 6.3e-06 25.7 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EPS30133.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Glyco_hydro_72 PF03198.14 EPS30134.1 - 9.3e-97 324.1 0.5 1.3e-96 323.6 0.5 1.2 1 0 0 1 1 1 1 Glucanosyltransferase Peripla_BP_4 PF13407.6 EPS30134.1 - 0.21 11.1 3.2 2.4 7.6 0.0 3.1 4 0 0 4 4 4 0 Periplasmic binding protein domain Sds3 PF08598.11 EPS30140.1 - 5.5e-46 157.3 4.2 1.2e-44 153.0 4.2 2.1 1 1 0 1 1 1 1 Sds3-like CMD PF02627.20 EPS30144.1 - 0.011 15.8 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family 2-oxogl_dehyd_N PF16078.5 EPS30144.1 - 0.052 13.2 0.1 0.099 12.3 0.1 1.5 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase N-terminus Aldose_epim PF01263.20 EPS30147.1 - 4.1e-46 157.7 0.5 5.5e-46 157.2 0.5 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase ACOX PF01756.19 EPS30148.1 - 9.4e-40 136.1 1.1 4.8e-39 133.8 0.0 2.4 3 0 0 3 3 3 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 EPS30148.1 - 5.4e-22 78.7 1.7 1.2e-21 77.5 1.7 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 EPS30148.1 - 1e-07 32.0 0.0 2.6e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EPS30148.1 - 0.094 12.9 0.5 0.34 11.1 0.5 2.0 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain AMP-binding PF00501.28 EPS30149.1 - 1.8e-48 165.2 0.0 2.2e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EPS30149.1 - 5.3e-11 43.3 0.0 1.1e-10 42.3 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ECH_1 PF00378.20 EPS30150.1 - 3.4e-23 82.2 0.0 3.9e-23 82.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EPS30150.1 - 1e-11 45.0 0.0 1.2e-11 44.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Actin PF00022.19 EPS30151.1 - 1.9e-20 72.9 0.0 3.5e-13 49.0 0.0 3.4 3 1 0 3 3 3 3 Actin XPG_I PF00867.18 EPS30152.1 - 3.1e-23 81.9 0.0 8.7e-23 80.5 0.0 1.8 1 0 0 1 1 1 1 XPG I-region GEN1_C PF18380.1 EPS30152.1 - 4.7e-21 75.7 0.2 1.4e-20 74.1 0.2 1.9 1 0 0 1 1 1 1 Holliday junction resolvase Gen1 C-terminal domain XPG_N PF00752.17 EPS30152.1 - 0.00016 22.1 0.0 0.00037 20.9 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain Peptidase_S28 PF05577.12 EPS30153.1 - 9.4e-50 169.7 3.4 2e-49 168.6 3.4 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase S28 DEAD PF00270.29 EPS30154.1 - 6.7e-38 130.2 0.0 1.7e-37 128.9 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPS30154.1 - 5.2e-24 84.7 0.0 1.3e-23 83.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EPS30154.1 - 4.3e-22 78.1 0.1 8.6e-22 77.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) AAA_22 PF13401.6 EPS30154.1 - 0.018 15.3 1.6 0.079 13.2 0.1 2.5 2 1 0 2 2 2 0 AAA domain TPPK_C PF12555.8 EPS30155.1 - 0.016 15.3 0.1 0.016 15.3 0.1 3.3 3 0 0 3 3 3 0 Thiamine pyrophosphokinase C terminal Ribosomal_S15 PF00312.22 EPS30157.1 - 1.2e-25 89.5 2.1 4.7e-25 87.6 0.1 2.7 3 0 0 3 3 3 1 Ribosomal protein S15 Ribosomal_S2 PF00318.20 EPS30158.1 - 8.7e-26 90.5 0.1 1.2e-14 54.1 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 EPS30158.1 - 1.5e-07 32.6 13.6 3.3e-07 31.5 13.6 1.6 1 0 0 1 1 1 1 40S ribosomal protein SA C-terminus Ras PF00071.22 EPS30159.1 - 1.1e-16 60.8 0.0 2.7e-16 59.6 0.0 1.6 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EPS30159.1 - 0.00014 22.0 0.0 0.00036 20.7 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPS30159.1 - 0.0012 18.3 0.0 0.018 14.5 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EPS30159.1 - 0.0026 17.0 0.0 0.0026 17.0 0.0 1.2 1 0 0 1 1 1 1 G-protein alpha subunit ABC_tran PF00005.27 EPS30159.1 - 0.0049 17.4 0.0 0.0066 17.0 0.0 1.4 1 1 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.23 EPS30159.1 - 0.0062 16.6 0.0 0.013 15.5 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EPS30159.1 - 0.01 16.1 0.0 0.017 15.4 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EPS30159.1 - 0.01 16.2 0.1 0.017 15.5 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EPS30159.1 - 0.013 15.3 0.3 0.027 14.2 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 EPS30159.1 - 0.015 15.2 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain RsgA_GTPase PF03193.16 EPS30159.1 - 0.022 14.7 0.1 0.051 13.5 0.1 1.6 2 0 0 2 2 2 0 RsgA GTPase Septin PF00735.18 EPS30159.1 - 0.045 13.0 0.0 0.056 12.7 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_25 PF13481.6 EPS30159.1 - 0.05 13.2 0.2 3.9 7.0 0.1 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EPS30159.1 - 0.051 14.0 0.1 0.17 12.3 0.1 1.8 1 1 0 1 1 1 0 RNA helicase Rad17 PF03215.15 EPS30159.1 - 0.056 13.4 0.0 0.083 12.8 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_24 PF13479.6 EPS30159.1 - 0.062 13.0 0.1 0.11 12.2 0.0 1.3 1 1 0 1 1 1 0 AAA domain PRK PF00485.18 EPS30159.1 - 0.072 12.8 0.0 0.09 12.5 0.0 1.3 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EPS30159.1 - 0.12 12.9 0.0 0.18 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain MCM PF00493.23 EPS30159.1 - 0.21 10.7 0.0 0.3 10.2 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain PseudoU_synth_1 PF01416.20 EPS30160.1 - 5.3e-34 116.9 0.0 1.7e-32 112.1 0.0 2.5 2 0 0 2 2 2 1 tRNA pseudouridine synthase ubiquitin PF00240.23 EPS30161.1 - 0.0021 17.8 0.0 0.003 17.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.10 EPS30161.1 - 0.0025 18.5 0.0 0.0039 17.9 0.0 1.3 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD DUF4661 PF15576.6 EPS30161.1 - 1.1 9.1 7.9 6.4 6.6 7.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4661) NPR3 PF03666.13 EPS30161.1 - 4 6.1 6.1 4.8 5.9 6.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Pribosyl_synth PF14572.6 EPS30162.1 - 5.6e-39 134.1 2.5 2.6e-34 118.9 0.7 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 EPS30162.1 - 1e-32 112.5 0.0 2.9e-32 111.0 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 EPS30162.1 - 6.5e-14 51.8 0.4 1.2e-13 50.9 0.4 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EPS30162.1 - 0.0013 18.2 0.2 0.0022 17.5 0.2 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase vATP-synt_AC39 PF01992.16 EPS30163.1 - 2.9e-106 355.8 0.0 3.2e-106 355.6 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Nop PF01798.18 EPS30164.1 - 9.9e-84 280.4 0.2 1.7e-83 279.7 0.2 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EPS30164.1 - 2.6e-22 79.0 1.0 2.6e-22 79.0 1.0 2.5 2 0 0 2 2 2 1 NOP5NT (NUC127) domain DALR_2 PF09190.11 EPS30164.1 - 0.016 15.7 0.0 0.53 10.8 0.0 3.3 2 0 0 2 2 2 0 DALR domain HWE_HK PF07536.14 EPS30164.1 - 0.044 14.5 1.2 7.8 7.3 0.1 3.5 3 0 0 3 3 3 0 HWE histidine kinase RNA_pol_Rpb4 PF03874.16 EPS30165.1 - 5.9e-07 29.8 0.2 0.0035 17.7 0.0 2.7 2 1 0 2 2 2 2 RNA polymerase Rpb4 FUSC-like PF12805.7 EPS30166.1 - 0.2 10.7 0.0 0.37 9.8 0.0 1.3 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS 2CSK_N PF08521.10 EPS30167.1 - 0.012 15.7 0.1 0.024 14.7 0.1 1.4 1 0 0 1 1 1 0 Two-component sensor kinase N-terminal SKA1 PF07160.12 EPS30167.1 - 0.046 13.6 0.3 0.1 12.4 0.3 1.6 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 CHDCT2 PF08074.11 EPS30167.1 - 0.052 13.7 0.5 0.37 11.0 0.1 2.3 3 0 0 3 3 3 0 CHDCT2 (NUC038) domain Band_7 PF01145.25 EPS30168.1 - 3e-29 102.3 3.4 5.3e-29 101.5 3.4 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 EPS30168.1 - 0.031 14.0 0.2 0.055 13.2 0.2 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family Acetyltransf_1 PF00583.25 EPS30169.1 - 5.6e-08 33.0 0.0 7.2e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EPS30169.1 - 6.4e-07 29.7 0.0 1.2e-06 28.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EPS30169.1 - 5.5e-05 23.1 0.0 6.4e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPS30169.1 - 0.0082 16.1 0.0 0.03 14.3 0.0 1.9 1 1 0 1 1 1 1 FR47-like protein adh_short PF00106.25 EPS30171.1 - 4.5e-17 62.1 0.0 6.2e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS30171.1 - 3.1e-12 46.5 0.0 4.3e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPS30171.1 - 0.0011 18.9 0.0 0.0066 16.4 0.0 1.9 1 1 0 1 1 1 1 KR domain F-box-like PF12937.7 EPS30172.1 - 3.6e-06 26.8 0.7 7.9e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EPS30172.1 - 6.3e-05 22.7 0.0 0.00014 21.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain CENP-L PF13092.6 EPS30173.1 - 1.5e-41 142.4 0.2 2.1e-41 141.8 0.2 1.2 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 Sulfate_transp PF00916.20 EPS30175.1 - 1.4e-77 261.0 16.3 2e-77 260.5 16.3 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EPS30175.1 - 4e-17 61.9 0.0 6.5e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 EPS30175.1 - 3.2e-05 24.2 0.0 6.6e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EPS30175.1 - 0.0013 19.1 13.2 0.0014 19.0 4.0 2.8 2 1 0 2 2 2 2 Molybdate transporter of MFS superfamily EIF_2_alpha PF07541.12 EPS30176.1 - 7e-38 129.3 0.1 1.4e-37 128.3 0.1 1.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 EPS30176.1 - 8.3e-13 48.5 0.5 1.7e-12 47.5 0.5 1.6 1 0 0 1 1 1 1 S1 RNA binding domain Troponin PF00992.20 EPS30176.1 - 0.031 14.6 0.7 0.072 13.4 0.7 1.6 1 0 0 1 1 1 0 Troponin DUF4265 PF14085.6 EPS30176.1 - 0.086 12.8 0.0 1.7 8.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4265) PKD_channel PF08016.12 EPS30177.1 - 0.0011 17.8 20.5 0.0058 15.4 19.6 2.2 1 1 0 1 1 1 1 Polycystin cation channel E1-E2_ATPase PF00122.20 EPS30178.1 - 5.9e-19 68.3 0.0 1.7e-18 66.8 0.0 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EPS30178.1 - 7.6e-15 55.8 1.6 2.1e-08 34.7 0.9 3.2 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EPS30178.1 - 0.0014 18.5 0.1 0.01 15.6 0.0 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EPS30178.1 - 0.002 18.2 0.2 0.12 12.5 0.0 3.1 3 0 0 3 3 3 1 Cation transport ATPase (P-type) S6PP PF05116.13 EPS30178.1 - 0.15 11.5 0.6 0.45 10.0 0.0 2.0 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase DUF4059 PF13268.6 EPS30178.1 - 3.6 8.1 6.7 29 5.2 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4059) Aldo_ket_red PF00248.21 EPS30179.1 - 5.9e-42 143.9 0.0 1.6e-31 109.6 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Aldo_ket_red PF00248.21 EPS30180.1 - 5.2e-12 45.6 0.0 7.5e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Kdo PF06293.14 EPS30181.1 - 9.5e-13 48.0 0.0 4.4e-12 45.8 0.0 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EPS30181.1 - 5.4e-09 36.3 0.1 0.00038 20.5 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 EPS30181.1 - 2.9e-08 33.4 0.0 4.1e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EPS30181.1 - 0.0015 17.4 0.0 0.002 17.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 EPS30181.1 - 0.0031 16.9 0.0 0.0038 16.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EPS30181.1 - 0.014 15.0 0.0 0.84 9.2 0.0 2.7 2 1 0 2 2 2 0 RIO1 family Choline_kinase PF01633.20 EPS30181.1 - 0.036 13.6 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.20 EPS30181.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Ferric_reduct PF01794.19 EPS30182.1 - 8.5e-19 67.9 13.6 8.7e-19 67.9 11.5 2.2 1 1 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EPS30182.1 - 1.5e-18 67.4 0.0 2.8e-16 60.0 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EPS30182.1 - 5.8e-14 52.1 0.0 5.1e-12 45.9 0.0 2.4 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 EPS30182.1 - 0.073 13.7 0.0 0.19 12.4 0.0 1.7 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain CLU PF13236.6 EPS30184.1 - 4.9e-75 252.2 0.0 8.8e-75 251.3 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 EPS30184.1 - 9.8e-55 185.3 0.1 2.9e-54 183.8 0.0 1.9 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 EPS30184.1 - 4.4e-26 91.0 7.2 1.7e-12 47.4 0.1 4.0 3 1 1 4 4 4 3 Tetratricopeptide repeat CLU_N PF15044.6 EPS30184.1 - 1.1e-25 89.8 0.1 3.2e-25 88.3 0.1 1.9 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.6 EPS30184.1 - 2.5e-21 74.8 1.0 9.6e-06 25.3 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EPS30184.1 - 4.4e-05 23.3 3.9 0.38 11.0 0.2 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EPS30184.1 - 0.0029 17.7 5.9 0.069 13.4 0.7 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF727 PF05303.12 EPS30184.1 - 0.0066 16.5 0.0 0.02 15.0 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_17 PF13431.6 EPS30184.1 - 0.45 11.0 4.6 3.3e+02 2.0 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat CPSF100_C PF13299.6 EPS30184.1 - 2.3 8.4 6.0 1.2 9.2 2.4 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal AAA_16 PF13191.6 EPS30185.1 - 7.3e-07 29.7 0.5 3.6e-06 27.5 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 EPS30185.1 - 0.0032 17.4 0.0 0.0069 16.3 0.0 1.5 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_25 PF13481.6 EPS30185.1 - 0.021 14.4 0.0 0.21 11.1 0.0 2.5 3 0 0 3 3 3 0 AAA domain Glycos_transf_2 PF00535.26 EPS30185.1 - 0.023 14.5 0.2 13 5.6 0.0 3.4 3 0 0 3 3 3 0 Glycosyl transferase family 2 AAA_7 PF12775.7 EPS30185.1 - 0.041 13.4 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Meiosis_expr PF15163.6 EPS30185.1 - 0.075 13.7 0.0 0.23 12.2 0.0 1.8 1 0 0 1 1 1 0 Meiosis-expressed ATPase PF06745.13 EPS30185.1 - 0.091 12.1 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.6 EPS30185.1 - 0.13 12.5 0.1 0.39 11.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain RTA1 PF04479.13 EPS30187.1 - 6.7e-73 244.7 7.8 9.5e-73 244.2 7.8 1.2 1 0 0 1 1 1 1 RTA1 like protein Deltaretro_Tax PF05599.11 EPS30187.1 - 0.13 12.8 0.1 2.5 8.7 0.0 2.6 3 0 0 3 3 3 0 Deltaretrovirus Tax protein XFP_N PF09364.10 EPS30188.1 - 4.9e-151 502.7 0.0 6.6e-151 502.2 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP_C PF09363.10 EPS30188.1 - 5.4e-78 261.1 0.0 7.9e-78 260.6 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain XFP PF03894.15 EPS30188.1 - 4.5e-77 257.7 0.0 7e-77 257.1 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase TPP_enzyme_C PF02775.21 EPS30188.1 - 0.036 13.9 0.1 0.097 12.5 0.1 1.7 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transket_pyr PF02779.24 EPS30188.1 - 0.15 11.7 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 Transketolase, pyrimidine binding domain Acetate_kinase PF00871.17 EPS30189.1 - 7.9e-90 301.4 0.0 9.4e-90 301.1 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family Ras PF00071.22 EPS30193.1 - 2.2e-56 189.9 0.0 2.9e-56 189.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EPS30193.1 - 9.1e-35 119.5 0.0 2.1e-34 118.3 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPS30193.1 - 3.8e-14 52.5 0.0 5.9e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EPS30193.1 - 4.1e-05 23.6 0.1 9.2e-05 22.5 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EPS30193.1 - 7.5e-05 22.2 0.0 0.0001 21.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EPS30193.1 - 0.00016 21.3 0.0 0.00024 20.7 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EPS30193.1 - 0.0003 21.2 0.1 0.0005 20.5 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EPS30193.1 - 0.12 12.3 0.0 2 8.3 0.0 2.3 3 0 0 3 3 3 0 RsgA GTPase Ribosomal_S7e PF01251.18 EPS30194.1 - 2e-83 278.7 0.8 2.4e-83 278.4 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Dynactin_p62 PF05502.13 EPS30195.1 - 6.9e-192 638.5 0.0 1.1e-191 637.8 0.0 1.2 1 0 0 1 1 1 1 Dynactin p62 family Trm112p PF03966.16 EPS30195.1 - 0.11 13.1 1.5 10 6.8 0.0 3.2 3 0 0 3 3 3 0 Trm112p-like protein Mu-like_Com PF10122.9 EPS30195.1 - 3.8 7.0 7.0 3.7 7.1 1.6 3.0 2 0 0 2 2 2 0 Mu-like prophage protein Com Pox_Ag35 PF03286.14 EPS30195.1 - 5.4 6.8 6.5 1.6 8.5 2.0 2.0 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Methyltransf_11 PF08241.12 EPS30196.1 - 2.2e-11 44.3 0.0 5.2e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPS30196.1 - 2.7e-10 40.3 0.0 4.2e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPS30196.1 - 1.2e-08 35.6 0.0 2.3e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPS30196.1 - 4.5e-08 33.7 0.0 1.5e-07 32.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPS30196.1 - 9.5e-06 25.5 0.0 2.1e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPS30196.1 - 0.0068 15.8 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family P16-Arc PF04699.14 EPS30197.1 - 4.6e-48 163.5 0.0 5.3e-48 163.3 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) 2-Hacid_dh_C PF02826.19 EPS30198.1 - 4.3e-39 133.7 0.0 6.2e-39 133.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EPS30198.1 - 8.2e-18 64.4 0.0 9.3e-18 64.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 EPS30198.1 - 0.05 13.7 0.1 0.93 9.5 0.0 2.7 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Ysc84 PF04366.12 EPS30199.1 - 4e-35 120.4 0.1 6.7e-35 119.6 0.1 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator Cation_ATPase_C PF00689.21 EPS30200.1 - 3.8e-49 166.9 8.6 3.8e-49 166.9 8.6 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EPS30200.1 - 3.9e-38 130.8 0.1 3.9e-38 130.8 0.1 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 EPS30200.1 - 4.8e-20 71.4 0.0 9.1e-20 70.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EPS30200.1 - 1.1e-16 61.8 0.7 3.3e-16 60.2 0.7 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EPS30200.1 - 1.5e-08 34.2 0.1 1.1e-07 31.4 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EPS30200.1 - 0.00038 20.3 0.0 0.0028 17.4 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF2227 PF09988.9 EPS30200.1 - 0.072 13.0 1.8 0.8 9.6 1.2 2.6 2 0 0 2 2 2 0 Uncharacterized metal-binding protein (DUF2227) DUF1774 PF08611.10 EPS30200.1 - 0.11 12.9 0.1 0.11 12.9 0.1 3.0 3 0 0 3 3 3 0 Fungal protein of unknown function (DUF1774) Adeno_E3_CR2 PF02439.15 EPS30202.1 - 0.0015 18.3 0.1 0.0035 17.1 0.1 1.6 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 SKG6 PF08693.10 EPS30202.1 - 0.2 11.1 0.9 0.5 9.8 0.9 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Plasmodium_Vir PF05795.11 EPS30202.1 - 0.26 10.7 1.7 0.36 10.2 1.7 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein EB1 PF03271.17 EPS30204.1 - 6.5e-17 61.5 1.8 1.5e-16 60.4 1.8 1.6 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 EPS30204.1 - 3.1e-06 27.3 0.2 5.3e-06 26.6 0.2 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Herpes_UL6 PF01763.16 EPS30204.1 - 0.0061 15.1 0.1 0.011 14.3 0.0 1.4 2 0 0 2 2 2 1 Herpesvirus UL6 like CH_2 PF06294.11 EPS30204.1 - 0.013 15.6 0.1 0.021 14.9 0.1 1.4 1 0 0 1 1 1 0 CH-like domain in sperm protein WD40 PF00400.32 EPS30205.1 - 1.1e-28 98.9 12.3 4.4e-05 24.2 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.7 EPS30205.1 - 3e-08 33.4 0.1 6.4e-08 32.4 0.1 1.6 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 EPS30205.1 - 2e-05 24.8 0.8 0.74 10.2 0.0 4.8 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EPS30205.1 - 0.00052 19.7 0.1 0.38 10.3 0.0 2.4 1 1 1 2 2 2 2 PQQ-like domain F-box PF00646.33 EPS30205.1 - 0.00055 19.7 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 F-box domain PQQ PF01011.21 EPS30205.1 - 0.0046 16.8 0.1 8.5 6.5 0.1 3.2 3 0 0 3 3 3 2 PQQ enzyme repeat WD40_like PF17005.5 EPS30205.1 - 0.0083 15.5 0.0 0.076 12.3 0.0 2.1 2 0 0 2 2 2 1 WD40-like domain Elongin_A PF06881.11 EPS30205.1 - 0.0089 16.5 0.0 0.017 15.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box_4 PF15966.5 EPS30205.1 - 0.013 15.4 0.0 0.032 14.1 0.0 1.7 1 0 0 1 1 1 0 F-box PQQ_3 PF13570.6 EPS30205.1 - 0.062 13.8 3.0 2.2 8.9 0.1 4.0 3 1 1 4 4 4 0 PQQ-like domain ADH_zinc_N PF00107.26 EPS30206.1 - 3.3e-17 62.7 0.1 1.4e-16 60.7 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPS30206.1 - 2.8e-15 56.1 6.9 1.4e-13 50.6 6.9 2.3 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.19 EPS30206.1 - 9.4e-05 21.8 0.3 0.00016 21.0 0.3 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 EPS30206.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DHDPS PF00701.22 EPS30207.1 - 1.1e-30 106.4 0.0 3.1e-22 78.6 0.0 2.0 2 0 0 2 2 2 2 Dihydrodipicolinate synthetase family GFO_IDH_MocA PF01408.22 EPS30208.1 - 6.3e-10 39.9 0.2 1.7e-09 38.5 0.2 1.9 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold PHD PF00628.29 EPS30209.1 - 2.5e-05 24.1 10.0 4.8e-05 23.2 10.0 1.5 1 0 0 1 1 1 1 PHD-finger ING PF12998.7 EPS30209.1 - 0.00065 20.2 0.0 0.0013 19.3 0.0 1.5 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding zf-HC5HC2H PF13771.6 EPS30209.1 - 0.039 14.2 2.0 0.076 13.3 2.0 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain DUF4226 PF10774.9 EPS30210.1 - 0.076 13.3 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4226) TENA_THI-4 PF03070.16 EPS30211.1 - 3.3e-11 43.4 0.0 3.4e-05 23.7 0.0 3.2 4 0 0 4 4 4 2 TENA/THI-4/PQQC family Peroxidase_2 PF01328.17 EPS30211.1 - 0.13 12.8 0.0 1.3 9.5 0.0 2.2 2 0 0 2 2 2 0 Peroxidase, family 2 Forkhead PF00250.18 EPS30212.1 - 1e-35 121.8 1.0 1.8e-35 121.0 1.0 1.4 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 EPS30212.1 - 2.1e-07 31.2 0.0 5.3e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 FHA domain DUF2071 PF09844.9 EPS30212.1 - 0.14 11.7 0.1 0.31 10.7 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (COG2071) zf-C2H2 PF00096.26 EPS30213.1 - 6.6e-08 32.6 13.6 3.5e-05 24.0 2.8 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EPS30213.1 - 1.2e-05 25.4 6.4 2.7e-05 24.4 3.3 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EPS30213.1 - 0.00011 22.7 1.7 0.00011 22.7 1.7 3.3 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_8 PF15909.5 EPS30213.1 - 0.00088 19.5 2.1 0.0021 18.3 2.1 1.7 1 0 0 1 1 1 1 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 EPS30213.1 - 0.0027 17.6 1.3 0.0084 16.1 1.3 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EPS30213.1 - 0.0033 17.7 2.1 0.0039 17.4 0.7 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.18 EPS30213.1 - 0.016 15.9 3.8 0.32 11.7 2.5 2.4 2 0 0 2 2 2 0 TRAF-type zinc finger FOXP-CC PF16159.5 EPS30213.1 - 0.05 14.2 7.3 1.5 9.5 0.3 3.3 1 1 2 3 3 3 0 FOXP coiled-coil domain 2OG-FeII_Oxy_3 PF13640.6 EPS30214.1 - 6.5e-12 46.2 0.1 1.1e-11 45.4 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.18 EPS30216.1 - 1.1e-26 93.4 0.0 2.2e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS30216.1 - 1.2e-10 41.4 12.9 2.1e-10 40.6 12.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EPS30217.1 - 0.00073 18.6 1.5 0.0009 18.3 1.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS30218.1 - 2.3e-108 363.0 23.2 2.6e-108 362.8 23.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS30218.1 - 1.1e-28 100.2 46.0 3.7e-27 95.2 29.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3899 PF13038.6 EPS30218.1 - 0.27 11.8 2.2 1.1 9.7 2.2 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) Fungal_trans_2 PF11951.8 EPS30219.1 - 2e-06 26.9 0.4 3.4e-06 26.1 0.4 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Sigma70_r2 PF04542.14 EPS30219.1 - 0.0077 16.0 0.0 0.027 14.2 0.0 1.9 1 0 0 1 1 1 1 Sigma-70 region 2 APH PF01636.23 EPS30220.1 - 5e-07 29.9 0.0 8.1e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family PHD PF00628.29 EPS30221.1 - 2.2e-10 40.3 7.2 2.2e-10 40.3 7.2 2.1 2 0 0 2 2 2 1 PHD-finger APH PF01636.23 EPS30221.1 - 0.018 15.0 2.0 0.042 13.8 0.0 2.4 2 1 0 2 2 2 0 Phosphotransferase enzyme family ORC6 PF05460.13 EPS30221.1 - 0.21 10.8 10.0 0.41 9.9 10.0 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Meth_synt_2 PF01717.18 EPS30225.1 - 1.5e-09 37.6 0.0 1.8e-06 27.5 0.0 2.4 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain DUF4790 PF16037.5 EPS30225.1 - 0.087 13.3 0.0 11 6.6 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4790) Hva1_TUDOR PF11160.8 EPS30226.1 - 2.2e-19 69.3 2.3 2.5e-19 69.2 2.3 1.0 1 0 0 1 1 1 1 Hypervirulence associated proteins TUDOR domain Arf PF00025.21 EPS30227.1 - 5.2e-71 237.7 0.2 6e-71 237.5 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EPS30227.1 - 3.9e-16 59.4 0.1 5.4e-16 58.9 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EPS30227.1 - 5.3e-14 52.1 0.0 5.9e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EPS30227.1 - 1.4e-13 50.8 1.0 2.9e-09 36.6 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EPS30227.1 - 2.2e-12 46.8 0.1 2.8e-12 46.5 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EPS30227.1 - 2.7e-10 40.0 0.0 3.2e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EPS30227.1 - 1e-05 25.6 0.0 1.3e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EPS30227.1 - 0.011 15.3 0.3 0.018 14.6 0.2 1.5 1 1 0 1 1 1 0 Ferrous iron transport protein B 6PF2K PF01591.18 EPS30227.1 - 0.016 14.5 0.2 0.029 13.7 0.2 1.6 1 1 0 1 1 1 0 6-phosphofructo-2-kinase Ribosomal_S8 PF00410.19 EPS30229.1 - 4e-17 62.3 0.0 5.7e-16 58.6 0.0 2.2 1 1 0 1 1 1 1 Ribosomal protein S8 3Beta_HSD PF01073.19 EPS30230.1 - 3.1e-53 180.6 0.0 4e-53 180.2 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EPS30230.1 - 9.4e-41 139.9 0.0 1.1e-40 139.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EPS30230.1 - 5.3e-19 68.8 0.0 8.4e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EPS30230.1 - 1.6e-17 63.5 0.0 2.2e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EPS30230.1 - 5.3e-15 55.3 0.0 5.7e-12 45.4 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 EPS30230.1 - 2.5e-11 43.8 0.0 3.4e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EPS30230.1 - 4e-09 36.0 0.0 1.4e-08 34.3 0.0 1.9 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 EPS30230.1 - 5.7e-07 29.6 0.0 1.9e-06 27.9 0.0 1.8 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 EPS30230.1 - 2.6e-06 27.0 0.0 4.6e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 EPS30230.1 - 0.00023 21.5 0.0 0.00042 20.6 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 EPS30230.1 - 0.00066 19.9 0.0 0.0016 18.6 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain adh_short_C2 PF13561.6 EPS30230.1 - 0.00093 18.8 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 EPS30230.1 - 0.0054 16.3 0.0 0.011 15.3 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 EPS30230.1 - 0.17 12.3 0.0 0.3 11.5 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain AAA_lid_8 PF17868.1 EPS30231.1 - 2.9 7.9 5.0 1.8 8.5 0.0 2.9 3 1 1 4 4 4 0 AAA lid domain STIL_N PF15253.6 EPS30232.1 - 0.5 9.3 3.3 0.84 8.5 3.3 1.3 1 0 0 1 1 1 0 SCL-interrupting locus protein N-terminus Iso_dh PF00180.20 EPS30233.1 - 4.3e-98 328.7 0.0 7e-98 328.0 0.0 1.3 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF1769 PF08588.10 EPS30234.1 - 8.2e-27 93.2 0.3 2.4e-26 91.7 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1769) VGPC1_C PF16799.5 EPS30235.1 - 0.064 13.2 2.7 0.18 11.8 0.1 2.9 3 0 0 3 3 3 0 C-terminal membrane-localisation domain of ion-channel, VCN1 TACC_C PF05010.14 EPS30235.1 - 0.16 11.8 26.7 0.21 11.4 16.5 3.6 3 1 1 4 4 4 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal GAS PF13851.6 EPS30235.1 - 0.42 9.9 30.8 0.21 10.9 16.1 4.6 3 1 2 5 5 5 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 EPS30235.1 - 0.57 10.2 13.2 0.12 12.4 3.9 3.8 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) Tup_N PF08581.10 EPS30235.1 - 1.6 9.0 28.2 0.1 12.9 1.1 5.4 5 1 1 6 6 6 0 Tup N-terminal Fib_alpha PF08702.10 EPS30235.1 - 2.2 8.5 19.7 0.43 10.8 5.9 4.6 3 1 2 6 6 6 0 Fibrinogen alpha/beta chain family BLOC1_2 PF10046.9 EPS30235.1 - 6 7.2 19.0 2.2 8.6 3.1 4.7 2 1 2 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Filament PF00038.21 EPS30235.1 - 6.5 6.2 38.4 0.19 11.3 6.7 3.4 3 1 1 4 4 4 0 Intermediate filament protein DUF3506 PF12014.8 EPS30236.1 - 4.1e-53 179.1 0.0 9.8e-53 177.9 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3506) F-box-like PF12937.7 EPS30236.1 - 5.3e-10 39.0 0.1 1.2e-09 38.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EPS30236.1 - 4.3e-06 26.5 0.1 1e-05 25.3 0.1 1.7 1 0 0 1 1 1 1 F-box domain DUF1748 PF08520.10 EPS30237.1 - 5.2e-37 125.6 0.1 5.8e-37 125.4 0.1 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Peptidase_S15 PF02129.18 EPS30237.1 - 0.022 14.4 0.4 0.023 14.3 0.4 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) PK PF00224.21 EPS30238.1 - 6.5e-175 581.0 3.1 8.1e-175 580.7 3.1 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EPS30238.1 - 1.2e-38 131.9 0.0 3.1e-38 130.6 0.0 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EPS30238.1 - 0.00029 20.1 0.2 0.0008 18.6 0.1 1.7 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.25 EPS30238.1 - 0.028 13.4 0.2 0.22 10.5 0.0 2.0 2 0 0 2 2 2 0 IMP dehydrogenase / GMP reductase domain KH_5 PF13184.6 EPS30238.1 - 0.074 13.2 0.4 0.21 11.7 0.4 1.7 1 0 0 1 1 1 0 NusA-like KH domain PIP5K PF01504.18 EPS30239.1 - 4.1e-34 118.0 0.1 1.1e-25 90.4 0.1 2.8 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 EPS30239.1 - 9.6e-28 97.0 0.0 1.6e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 EPS30239.1 - 2.9e-14 53.0 5.1 2.9e-14 53.0 5.1 2.0 2 0 0 2 2 2 1 FYVE zinc finger C1_1 PF00130.22 EPS30239.1 - 0.0041 17.0 4.1 0.011 15.6 4.1 1.7 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) XPC-binding PF09280.11 EPS30239.1 - 0.38 10.5 2.5 1.2 9.0 2.5 1.8 1 0 0 1 1 1 0 XPC-binding domain SUR7 PF06687.12 EPS30241.1 - 2.3e-52 177.7 11.6 2.9e-52 177.4 11.6 1.1 1 0 0 1 1 1 1 SUR7/PalI family OPT PF03169.15 EPS30241.1 - 1.9e-05 23.5 2.5 2.8e-05 23.0 2.5 1.3 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF373 PF04123.13 EPS30241.1 - 0.1 12.0 4.3 0.16 11.4 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) SLATT_4 PF18186.1 EPS30241.1 - 0.81 9.3 1.9 9.8 5.8 2.4 2.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 Cellulase PF00150.18 EPS30243.1 - 6.6e-57 193.1 2.9 8.4e-57 192.7 2.9 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Lipase_GDSL PF00657.22 EPS30244.1 - 4.2e-09 36.7 0.0 5.1e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 EPS30244.1 - 4.6e-06 27.1 0.1 5.8e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family WD40 PF00400.32 EPS30245.1 - 1.4e-13 51.0 24.8 6.8e-07 29.9 0.7 9.5 10 0 0 10 10 10 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS30245.1 - 0.0059 16.9 0.0 1.4 9.3 0.0 4.3 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain XPG_N PF00752.17 EPS30246.1 - 1.6e-35 121.6 0.0 4.5e-35 120.2 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EPS30246.1 - 7.3e-25 87.1 0.0 2.4e-24 85.5 0.0 2.0 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 EPS30246.1 - 0.0011 19.5 0.0 0.0067 17.0 0.0 2.2 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold UIM PF02809.20 EPS30246.1 - 0.03 14.2 0.4 0.03 14.2 0.4 3.6 3 0 0 3 3 3 0 Ubiquitin interaction motif Cauli_DNA-bind PF03310.13 EPS30246.1 - 0.055 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Caulimovirus DNA-binding protein Pil1 PF13805.6 EPS30247.1 - 3.1e-124 413.7 0.1 4.2e-124 413.3 0.1 1.2 1 0 0 1 1 1 1 Eisosome component PIL1 Methyltransf_25 PF13649.6 EPS30248.1 - 2.4e-18 66.6 0.0 4.5e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS30248.1 - 2.9e-16 59.9 0.0 4.8e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPS30248.1 - 1e-11 45.4 0.0 1.9e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPS30248.1 - 6.2e-10 39.1 0.0 9e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPS30248.1 - 6.5e-09 35.8 0.0 8.5e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 EPS30248.1 - 2.7e-06 26.8 0.0 3.7e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain MTS PF05175.14 EPS30248.1 - 2.6e-05 23.8 0.0 4.5e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 EPS30248.1 - 0.0005 19.5 0.0 0.00075 18.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EPS30248.1 - 0.00052 19.4 0.0 0.00071 18.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase CheR PF01739.18 EPS30248.1 - 0.092 12.2 0.0 3.2 7.2 0.0 2.3 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_33 PF10017.9 EPS30248.1 - 0.17 11.0 0.0 0.39 9.8 0.0 1.6 1 1 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent bZIP_2 PF07716.15 EPS30249.1 - 2.9e-13 49.7 13.5 5.4e-13 48.8 13.5 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EPS30249.1 - 0.0049 16.9 11.9 0.0095 16.0 11.9 1.5 1 0 0 1 1 1 1 bZIP transcription factor DUF3552 PF12072.8 EPS30249.1 - 0.024 14.1 6.6 0.037 13.4 6.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF4094 PF13334.6 EPS30249.1 - 0.03 14.7 0.4 0.059 13.8 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) FPP PF05911.11 EPS30249.1 - 0.057 11.6 5.6 0.078 11.2 5.6 1.0 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Fungal_trans PF04082.18 EPS30250.1 - 2.6e-17 62.7 0.2 4.3e-17 62.0 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Spc7_N PF15402.6 EPS30251.1 - 0 1030.7 86.7 1e-204 682.6 49.5 3.8 2 1 2 4 4 4 2 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.11 EPS30251.1 - 4.2e-125 416.7 8.6 9.4e-125 415.6 8.6 1.6 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF3027 PF11228.8 EPS30251.1 - 0.23 11.5 1.2 0.44 10.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3027) GvpL_GvpF PF06386.11 EPS30251.1 - 6.9 6.5 20.7 0.22 11.4 10.5 2.7 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF Ribosomal_S17_N PF16205.5 EPS30252.1 - 1.2e-34 118.5 1.2 2e-34 117.8 1.2 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 EPS30252.1 - 7.7e-28 96.4 0.8 7.7e-28 96.4 0.8 1.7 2 0 0 2 2 2 1 Ribosomal protein S17 ANTH PF07651.16 EPS30253.1 - 2.2e-62 210.6 0.2 2.8e-62 210.2 0.2 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 EPS30253.1 - 1.4e-08 34.8 0.1 7.6e-08 32.4 0.0 1.9 2 0 0 2 2 2 1 ENTH domain Fungal_trans_2 PF11951.8 EPS30256.1 - 5.1e-08 32.1 0.9 1.9e-07 30.3 0.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain PAP1 PF08601.10 EPS30256.1 - 0.15 11.8 7.8 0.21 11.3 7.8 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 FAM199X PF15814.5 EPS30256.1 - 0.25 10.4 3.8 0.41 9.7 3.8 1.2 1 0 0 1 1 1 0 Protein family FAM199X Methyltransf_23 PF13489.6 EPS30257.1 - 3.6e-14 52.9 0.0 5e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPS30257.1 - 2.3e-08 34.6 0.0 9.7e-08 32.6 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPS30257.1 - 2.2e-05 25.1 0.0 0.00022 21.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS30257.1 - 8.1e-05 23.2 0.0 0.00018 22.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EPS30257.1 - 0.0017 17.8 0.0 0.0041 16.6 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.6 EPS30257.1 - 0.0021 17.8 0.0 0.047 13.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EPS30257.1 - 0.032 13.8 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.18 EPS30257.1 - 0.07 12.4 0.0 0.19 11.0 0.0 1.8 1 1 0 1 1 1 0 O-methyltransferase domain CheR PF01739.18 EPS30257.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain CMAS PF02353.20 EPS30257.1 - 0.19 11.0 0.0 0.65 9.2 0.0 1.9 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Epimerase PF01370.21 EPS30258.1 - 5.1e-20 72.0 0.0 7.9e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EPS30258.1 - 6.8e-17 61.4 0.0 8.7e-17 61.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EPS30258.1 - 6.5e-10 39.2 0.0 8.9e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EPS30258.1 - 3.3e-09 36.6 0.0 5.4e-07 29.3 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EPS30258.1 - 2.9e-07 29.9 0.0 7e-07 28.7 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.13 EPS30258.1 - 2.6e-06 27.2 0.0 8.7e-06 25.5 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 EPS30258.1 - 0.0028 17.2 0.0 0.0052 16.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 EPS30258.1 - 0.0045 16.2 0.0 0.037 13.1 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Glyco_hydro_11 PF00457.17 EPS30259.1 - 3e-79 264.8 19.5 3.5e-79 264.6 19.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 DUF4635 PF15466.6 EPS30260.1 - 0.058 12.9 0.6 0.058 12.9 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4635) Pro_Al_protease PF02983.14 EPS30260.1 - 0.15 12.1 0.1 0.41 10.8 0.0 1.9 2 1 0 2 2 2 0 Alpha-lytic protease prodomain ING PF12998.7 EPS30260.1 - 0.28 11.8 4.3 0.28 11.8 1.5 2.0 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding POTRA_TamA_1 PF17243.2 EPS30260.1 - 0.34 11.0 2.5 0.3 11.2 0.5 1.9 2 0 0 2 2 2 0 POTRA domain TamA domain 1 Gpr1_Fun34_YaaH PF01184.19 EPS30261.1 - 4.8e-93 310.5 22.0 6e-93 310.2 22.0 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family MFS_1 PF07690.16 EPS30263.1 - 9.4e-35 120.2 17.4 1.4e-34 119.6 17.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 EPS30263.1 - 0.0022 17.3 3.3 0.0022 17.3 3.3 2.2 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB Wzy_C PF04932.15 EPS30263.1 - 0.015 14.9 0.7 0.55 9.9 0.3 2.6 2 1 0 2 2 2 0 O-Antigen ligase Phage_holin_2_4 PF16082.5 EPS30263.1 - 0.016 14.9 0.3 4.9 7.0 0.0 3.1 2 1 0 2 2 2 0 Bacteriophage holin family, superfamily II-like DUF2723 PF11028.8 EPS30263.1 - 7.6 6.4 12.1 0.36 10.7 0.6 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2723) Oxidored_FMN PF00724.20 EPS30264.1 - 2.2e-94 316.5 0.0 2.6e-94 316.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Tautomerase PF01361.21 EPS30264.1 - 0.055 13.4 0.0 0.43 10.5 0.0 2.2 2 0 0 2 2 2 0 Tautomerase enzyme YabA PF06156.13 EPS30265.1 - 0.092 13.4 3.2 0.32 11.6 3.2 2.0 1 0 0 1 1 1 0 Initiation control protein YabA WD40 PF00400.32 EPS30267.1 - 1.1e-19 70.4 12.9 0.00023 21.9 0.1 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS30267.1 - 3.8e-17 62.4 0.0 3.9e-06 27.1 0.0 5.5 4 2 2 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EPS30267.1 - 4.2e-05 23.5 0.3 0.02 14.8 0.0 2.7 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A HIRA_B PF09453.10 EPS30267.1 - 7.6e-05 22.5 0.2 0.00032 20.4 0.2 2.2 1 0 0 1 1 1 1 HIRA B motif Ge1_WD40 PF16529.5 EPS30267.1 - 0.023 13.7 0.0 56 2.5 0.0 3.8 2 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EPS30267.1 - 0.041 13.8 5.7 7.6 6.6 0.3 4.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat WD40_like PF17005.5 EPS30267.1 - 0.26 10.6 0.0 0.96 8.7 0.0 1.8 2 0 0 2 2 2 0 WD40-like domain Glyco_transf_20 PF00982.21 EPS30268.1 - 4e-147 490.7 0.0 5.3e-147 490.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EPS30268.1 - 6.8e-21 74.5 0.0 1.1e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase MBA1 PF07961.11 EPS30268.1 - 0.013 14.6 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 MBA1-like protein Pkinase PF00069.25 EPS30269.1 - 2e-05 24.1 0.0 0.00059 19.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Rad4 PF03835.15 EPS30270.1 - 1.4e-14 54.1 2.3 2.9e-14 53.0 2.3 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 EPS30270.1 - 5.5e-13 49.4 1.6 1.3e-12 48.2 1.6 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily CAP_N PF01213.19 EPS30270.1 - 4.5 6.7 6.6 7.1 6.0 6.6 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Glyco_hydro_71 PF03659.14 EPS30272.1 - 3.8e-130 434.0 6.9 4.5e-130 433.8 6.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF4434 PF14488.6 EPS30272.1 - 0.074 13.1 0.1 0.15 12.1 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4434) PAP2_3 PF14378.6 EPS30273.1 - 1.4e-21 77.1 25.9 9.3e-19 67.8 5.5 2.9 3 0 0 3 3 3 2 PAP2 superfamily PAP2 PF01569.21 EPS30273.1 - 0.01 15.6 4.6 0.01 15.6 4.6 2.2 1 1 0 2 2 2 0 PAP2 superfamily PAP2_C PF14360.6 EPS30273.1 - 0.031 14.8 7.3 0.031 14.8 7.3 3.3 4 1 0 4 4 4 0 PAP2 superfamily C-terminal DUF4233 PF14017.6 EPS30273.1 - 0.043 14.1 4.6 0.11 12.9 4.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4233) Memo PF01875.17 EPS30274.1 - 1.2e-62 211.6 0.0 1.4e-62 211.3 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein LSM PF01423.22 EPS30276.1 - 1.9e-07 30.7 0.0 4.2e-07 29.6 0.0 1.5 1 1 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EPS30276.1 - 0.00016 21.7 0.0 0.00025 21.1 0.0 1.5 1 1 0 1 1 1 1 Ataxin 2 SM domain DCR PF14047.6 EPS30276.1 - 0.039 14.2 0.0 0.073 13.3 0.0 1.5 2 0 0 2 2 2 0 Dppa2/4 conserved region Gemin6 PF06372.12 EPS30276.1 - 0.1 12.2 0.0 0.14 11.7 0.0 1.3 1 1 0 1 1 1 0 Gemin6 protein DUF2380 PF09533.10 EPS30276.1 - 0.16 11.6 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) Metallophos PF00149.28 EPS30277.1 - 4.5e-37 128.5 0.1 6.8e-37 127.9 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EPS30277.1 - 5e-17 62.1 0.1 8.6e-17 61.3 0.1 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain GREB1 PF15782.5 EPS30278.1 - 5.1 4.1 9.9 6.3 3.8 9.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer RabGAP-TBC PF00566.18 EPS30279.1 - 8.1e-32 110.6 4.1 1.5e-31 109.8 4.1 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF4407 PF14362.6 EPS30279.1 - 0.57 9.5 3.9 0.87 8.9 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pkinase PF00069.25 EPS30280.1 - 2.6e-56 190.9 0.0 3.9e-56 190.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS30280.1 - 1.3e-19 70.5 0.0 2e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EPS30280.1 - 0.00074 18.6 0.0 0.0012 17.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EPS30280.1 - 0.00096 18.6 0.1 0.0017 17.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EPS30280.1 - 0.0016 17.8 0.0 0.0032 16.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EPS30280.1 - 0.0028 17.6 0.1 0.026 14.4 0.1 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.22 EPS30280.1 - 0.021 14.4 1.4 0.035 13.7 0.1 2.0 3 0 0 3 3 3 0 RIO1 family Pkinase_fungal PF17667.1 EPS30280.1 - 0.041 12.6 0.0 0.072 11.9 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Choline_kinase PF01633.20 EPS30280.1 - 0.23 11.0 0.1 0.39 10.2 0.1 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase LRR_6 PF13516.6 EPS30282.1 - 8.7e-14 50.3 0.4 0.058 13.5 0.0 6.5 6 0 0 6 6 6 3 Leucine Rich repeat F-box-like PF12937.7 EPS30282.1 - 2.3e-11 43.4 0.3 2.3e-11 43.4 0.3 2.6 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 EPS30282.1 - 1.7e-08 34.2 0.2 6.7e-08 32.2 0.2 2.1 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 EPS30282.1 - 3.4e-06 27.3 5.3 3.6 8.1 0.0 5.4 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) p47_phox_C PF08944.11 EPS30282.1 - 0.0024 17.2 0.2 0.0066 15.8 0.2 1.7 1 0 0 1 1 1 1 NADPH oxidase subunit p47Phox, C terminal domain LRR_1 PF00560.33 EPS30282.1 - 0.092 13.3 13.6 8.9 7.3 0.1 5.7 7 0 0 7 7 7 0 Leucine Rich Repeat Dehyd-heme_bind PF09098.10 EPS30283.1 - 0.0079 15.8 0.3 0.0094 15.6 0.3 1.3 1 0 0 1 1 1 1 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding Efg1 PF10153.9 EPS30285.1 - 8.3e-33 113.2 10.2 8.3e-33 113.2 10.2 2.8 3 0 0 3 3 3 1 rRNA-processing protein Efg1 zinc_ribbon_16 PF17034.5 EPS30286.1 - 5.5e-24 84.7 9.5 1.1e-23 83.8 9.5 1.5 1 0 0 1 1 1 1 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 EPS30286.1 - 0.00026 20.6 6.1 0.00026 20.6 6.1 2.9 3 0 0 3 3 3 1 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 EPS30286.1 - 0.0075 16.5 4.8 0.031 14.6 4.8 2.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EPS30286.1 - 0.78 10.1 10.1 0.37 11.2 4.0 2.8 2 0 0 2 2 2 0 Ring finger domain PTS_2-RNA PF01885.16 EPS30287.1 - 1.3e-67 227.3 0.0 1.6e-67 227.1 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Tir_receptor_C PF07489.11 EPS30287.1 - 5.3 6.9 15.3 0.31 11.0 9.8 1.6 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) C-terminus Dioxygenase_C PF00775.21 EPS30288.1 - 2.3e-47 160.8 0.0 3e-47 160.4 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 EPS30288.1 - 1.9e-27 94.9 0.1 2.8e-27 94.4 0.1 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 EPS30288.1 - 9.5e-05 22.6 0.0 0.00049 20.3 0.0 2.0 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain SpaA PF17802.1 EPS30288.1 - 0.03 14.7 0.0 0.059 13.7 0.0 1.5 1 0 0 1 1 1 0 Prealbumin-like fold domain Lipase_C PF18067.1 EPS30288.1 - 0.03 14.9 0.0 0.057 14.0 0.0 1.4 1 0 0 1 1 1 0 Lipase C-terminal domain DUF4198 PF10670.9 EPS30288.1 - 0.051 13.9 0.0 0.085 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) CarbopepD_reg_2 PF13715.6 EPS30288.1 - 0.15 12.0 0.0 2.9 8.0 0.0 2.6 3 0 0 3 3 3 0 CarboxypepD_reg-like domain Abhydrolase_1 PF00561.20 EPS30289.1 - 1.9e-23 83.4 0.1 2e-20 73.5 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EPS30289.1 - 5.4e-19 68.4 0.0 9e-19 67.7 0.0 1.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EPS30289.1 - 1.4e-15 58.5 0.1 1.9e-15 58.1 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 EPS30289.1 - 5.6e-07 28.6 0.0 7.9e-07 28.0 0.0 1.2 1 0 0 1 1 1 1 Ndr family Esterase PF00756.20 EPS30289.1 - 8.8e-05 22.3 0.3 0.0031 17.2 0.0 2.1 1 1 0 2 2 2 1 Putative esterase DLH PF01738.18 EPS30289.1 - 0.00013 21.6 0.0 0.33 10.5 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 EPS30289.1 - 0.00041 20.2 0.2 0.16 11.7 0.0 2.9 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Ser_hydrolase PF06821.13 EPS30289.1 - 0.0016 18.3 0.1 0.0097 15.8 0.0 2.1 1 1 0 2 2 2 1 Serine hydrolase Abhydrolase_5 PF12695.7 EPS30289.1 - 0.0074 16.1 0.0 0.073 12.8 0.1 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EPS30289.1 - 0.0083 15.6 0.0 1 8.8 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Thioesterase PF00975.20 EPS30289.1 - 0.021 15.0 0.0 0.036 14.2 0.0 1.5 1 1 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.13 EPS30289.1 - 0.029 14.1 0.5 0.045 13.5 0.5 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.14 EPS30289.1 - 0.067 12.7 0.1 0.17 11.4 0.1 1.6 1 1 0 1 1 1 0 Putative serine esterase (DUF676) BAAT_C PF08840.11 EPS30289.1 - 0.085 12.8 0.2 0.58 10.0 0.2 2.0 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Aldo_ket_red PF00248.21 EPS30291.1 - 1.2e-40 139.5 0.0 2.3e-28 99.3 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family Dev_Cell_Death PF10539.9 EPS30291.1 - 0.18 11.7 0.0 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 Development and cell death domain eRF1_1 PF03463.15 EPS30292.1 - 6.5e-47 158.8 0.0 1e-46 158.1 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 EPS30292.1 - 1.8e-19 70.3 0.0 3.6e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 EPS30292.1 - 9e-19 68.1 0.0 1.5e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 Uricase PF01014.18 EPS30292.1 - 0.12 12.7 0.1 3.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Uricase DUF413 PF04219.12 EPS30293.1 - 0.1 12.6 0.1 0.21 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF ER_lumen_recept PF00810.18 EPS30294.1 - 2.3e-43 148.5 8.4 4.3e-43 147.6 8.4 1.5 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 EPS30294.1 - 0.034 13.9 0.0 0.034 13.9 0.0 4.0 5 0 0 5 5 5 0 PQ loop repeat Myb_DNA-binding PF00249.31 EPS30295.1 - 8e-15 54.8 3.0 2e-09 37.5 0.7 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EPS30295.1 - 3e-08 33.8 1.3 4e-06 27.0 0.1 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EPS30295.1 - 0.024 14.5 1.2 0.031 14.2 1.2 1.2 1 0 0 1 1 1 0 Myb DNA-binding like Transp_cyt_pur PF02133.15 EPS30296.1 - 7.4e-18 64.5 39.4 1.1e-17 63.9 39.4 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin COX5B PF01215.19 EPS30297.1 - 7.3e-54 180.9 0.0 9.1e-54 180.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb LysM PF01476.20 EPS30298.1 - 0.00014 21.9 0.0 0.00044 20.3 0.0 1.9 2 0 0 2 2 2 1 LysM domain Chitin_bind_1 PF00187.19 EPS30298.1 - 0.07 13.6 7.9 0.32 11.5 7.9 2.2 1 0 0 1 1 1 0 Chitin recognition protein DUF2235 PF09994.9 EPS30299.1 - 4.7e-79 265.7 0.0 8.4e-79 264.9 0.0 1.4 2 0 0 2 2 2 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Myb_DNA-bind_6 PF13921.6 EPS30300.1 - 2.1e-11 43.9 0.2 2.6e-07 30.8 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EPS30300.1 - 3.1e-11 43.3 0.1 4.2e-05 23.6 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain PROCN PF08083.11 EPS30301.1 - 1.1e-234 778.6 8.3 1.1e-234 778.6 8.3 2.0 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 EPS30301.1 - 1.9e-126 420.3 1.4 3.6e-126 419.4 1.4 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 EPS30301.1 - 4.9e-85 283.3 1.5 9.1e-58 194.7 0.2 2.9 2 0 0 2 2 2 2 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 EPS30301.1 - 1.7e-80 268.3 2.2 4.8e-80 266.9 2.2 1.8 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 EPS30301.1 - 5.6e-71 236.9 0.1 1.2e-70 235.8 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 EPS30301.1 - 2.8e-48 162.9 0.0 9.8e-48 161.1 0.0 2.0 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.9 EPS30301.1 - 1.5e-47 159.9 0.4 4.2e-47 158.4 0.4 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 Hom_end_hint PF05203.16 EPS30301.1 - 1.1e-10 41.9 0.4 2.7e-10 40.6 0.0 1.8 2 0 0 2 2 2 1 Hom_end-associated Hint Ribosomal_L34e PF01199.18 EPS30302.1 - 4.5e-43 145.5 1.7 5.9e-43 145.1 1.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e Vps36-NZF-N PF16988.5 EPS30302.1 - 0.027 13.9 0.0 0.046 13.1 0.0 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Forkhead PF00250.18 EPS30303.1 - 5.2e-19 68.3 0.0 9.3e-19 67.5 0.0 1.3 1 0 0 1 1 1 1 Forkhead domain Cactin_mid PF10312.9 EPS30305.1 - 2.1e-64 216.9 5.5 3.4e-64 216.2 5.5 1.3 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.9 EPS30305.1 - 2.3e-58 195.5 5.4 3.9e-58 194.8 5.4 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein DUF1087 PF06465.13 EPS30305.1 - 0.024 14.6 1.5 0.057 13.5 0.3 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) SF3A2 PF16835.5 EPS30305.1 - 0.029 14.7 0.0 0.095 13.1 0.0 1.9 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) XLF PF09302.11 EPS30306.1 - 3.6e-51 173.9 0.0 6.6e-51 173.0 0.0 1.4 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component Sec39 PF08314.11 EPS30306.1 - 0.077 11.4 0.2 0.12 10.8 0.2 1.2 1 0 0 1 1 1 0 Secretory pathway protein Sec39 WD40 PF00400.32 EPS30307.1 - 4.2e-15 55.9 11.9 4.7e-05 24.1 0.1 6.8 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS30307.1 - 1.7e-07 31.4 0.1 2 8.7 0.0 5.2 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Zn_ribbon_17 PF17120.5 EPS30307.1 - 3.7 7.2 12.6 2.2 7.9 9.7 2.1 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 EPS30307.1 - 3.8 7.5 10.1 0.21 11.5 0.8 2.4 2 0 0 2 2 2 0 PHD-finger ABC_membrane PF00664.23 EPS30309.1 - 3.9e-33 115.3 7.2 9e-33 114.1 7.2 1.6 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EPS30309.1 - 1.2e-32 113.3 0.0 5.6e-32 111.1 0.0 2.1 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EPS30309.1 - 4e-07 29.7 1.2 1.2e-05 24.8 0.2 2.7 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EPS30309.1 - 0.0024 18.3 0.1 0.0064 16.9 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EPS30309.1 - 0.013 15.8 0.4 0.13 12.6 0.4 2.3 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EPS30309.1 - 0.014 15.1 0.0 0.031 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 EPS30309.1 - 0.019 15.2 0.4 0.42 10.9 0.4 2.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 EPS30309.1 - 0.039 13.7 0.2 0.13 12.0 0.2 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EPS30309.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase DUF498 PF04430.14 EPS30310.1 - 2e-28 98.6 0.0 6.3e-28 97.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF498/DUF598) DUF1131 PF06572.12 EPS30310.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1131) Alk_phosphatase PF00245.20 EPS30311.1 - 4.9e-110 368.3 0.2 6.3e-110 368.0 0.2 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 EPS30311.1 - 7.8e-05 22.2 0.1 0.00038 19.9 0.0 2.0 1 1 0 2 2 2 1 Metalloenzyme superfamily Glyco_hydro_16 PF00722.21 EPS30312.1 - 1.9e-44 151.3 8.6 3.3e-44 150.5 8.6 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.19 EPS30312.1 - 0.36 11.3 15.9 0.78 10.3 15.9 1.5 1 0 0 1 1 1 0 Chitin recognition protein Herpes_capsid PF06112.11 EPS30312.1 - 5.9 6.9 25.7 13 5.8 25.7 1.7 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Fungal_trans_2 PF11951.8 EPS30313.1 - 0.0047 15.8 0.1 0.006 15.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MIT PF04212.18 EPS30313.1 - 0.039 14.0 0.1 4.1 7.5 0.0 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain PMSR PF01625.21 EPS30314.1 - 1.3e-60 204.0 0.5 1.6e-60 203.8 0.5 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Kinesin PF00225.23 EPS30315.1 - 5.1e-116 387.2 0.0 8.6e-116 386.5 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EPS30315.1 - 1e-26 93.7 0.2 3.5e-26 91.9 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding AAA_33 PF13671.6 EPS30315.1 - 0.0022 18.2 0.5 0.18 12.0 0.0 3.6 3 0 0 3 3 3 1 AAA domain DUF5424 PF17462.2 EPS30315.1 - 0.076 12.9 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5424) Tim17 PF02466.19 EPS30317.1 - 0.011 16.1 1.1 0.022 15.1 1.0 1.5 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family cNMPbd_u2 PF16643.5 EPS30318.1 - 5.5e-40 137.4 2.1 1.8e-39 135.7 2.1 1.9 1 0 0 1 1 1 1 Unstructured region on cNMP-binding protein cNMP_binding PF00027.29 EPS30318.1 - 2.4e-34 117.3 0.0 8.4e-21 73.9 0.0 2.9 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.6 EPS30318.1 - 2.2e-09 36.6 5.0 0.83 9.9 0.0 7.8 9 0 0 9 9 9 3 Leucine Rich repeat LRR_4 PF12799.7 EPS30318.1 - 1e-07 32.1 0.0 0.29 11.6 0.0 5.5 5 1 2 7 7 7 3 Leucine Rich repeats (2 copies) F-box PF00646.33 EPS30318.1 - 1.4e-05 24.8 0.5 4e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EPS30318.1 - 1.7e-05 24.6 0.1 6.2e-05 22.8 0.1 1.9 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.33 EPS30318.1 - 0.00026 21.1 3.9 68 4.6 0.0 7.3 6 1 1 7 7 7 0 Leucine Rich Repeat Cupin_3 PF05899.12 EPS30318.1 - 0.042 13.5 0.1 1.9 8.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF861) SAM_Ste50p PF09235.10 EPS30318.1 - 0.074 13.3 0.4 6.6 7.1 0.2 3.1 2 1 0 2 2 2 0 Ste50p, sterile alpha motif PapG_N PF03627.13 EPS30319.1 - 0.16 11.6 0.0 0.16 11.6 0.0 1.0 1 0 0 1 1 1 0 PapG carbohydrate binding domain Slx4 PF09494.10 EPS30320.1 - 7e-26 90.0 0.1 1.4e-25 89.0 0.1 1.5 1 0 0 1 1 1 1 Slx4 endonuclease TP2 PF01254.18 EPS30321.1 - 8.7 7.0 13.8 10 6.7 9.9 2.3 1 1 1 2 2 2 0 Nuclear transition protein 2 Zn_clus PF00172.18 EPS30323.1 - 2.1e-05 24.6 10.9 3.8e-05 23.7 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TMF_DNA_bd PF12329.8 EPS30323.1 - 0.0069 16.4 5.1 0.63 10.1 1.6 2.5 2 0 0 2 2 2 2 TATA element modulatory factor 1 DNA binding MAD PF05557.13 EPS30323.1 - 0.01 14.2 8.5 0.17 10.2 8.7 2.1 1 1 0 1 1 1 0 Mitotic checkpoint protein DUF2205 PF10224.9 EPS30323.1 - 0.017 15.1 2.1 0.15 12.1 0.8 2.3 2 0 0 2 2 2 0 Short coiled-coil protein TSC22 PF01166.18 EPS30323.1 - 0.024 15.0 2.1 3.2 8.2 0.0 2.4 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF4618 PF15397.6 EPS30323.1 - 0.061 12.7 5.1 3.4 7.0 1.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) DivIC PF04977.15 EPS30323.1 - 0.082 12.7 9.6 2.1 8.2 0.6 2.4 2 0 0 2 2 2 0 Septum formation initiator DUF5082 PF16888.5 EPS30323.1 - 0.12 12.7 6.4 0.41 10.9 0.9 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF5082) DUF4407 PF14362.6 EPS30323.1 - 0.14 11.5 2.9 0.23 10.8 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PEP-utilisers_N PF05524.13 EPS30323.1 - 0.26 11.4 5.5 2.9 8.1 5.5 2.2 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal SlyX PF04102.12 EPS30323.1 - 0.48 11.1 12.3 7.5 7.2 5.2 3.3 3 0 0 3 3 3 0 SlyX SOGA PF11365.8 EPS30323.1 - 0.54 11.4 5.4 0.14 13.3 1.6 2.1 2 1 0 2 2 1 0 Protein SOGA ABC_tran_CTD PF16326.5 EPS30323.1 - 0.57 10.5 5.5 0.5 10.6 0.6 2.5 2 0 0 2 2 2 0 ABC transporter C-terminal domain MCC-bdg_PDZ PF10506.9 EPS30323.1 - 0.59 10.2 5.1 1.2 9.2 0.7 2.4 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF3450 PF11932.8 EPS30323.1 - 0.68 9.2 8.1 4.5 6.5 4.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) YabA PF06156.13 EPS30323.1 - 1 10.0 6.6 6.6 7.4 0.9 2.7 3 0 0 3 3 2 0 Initiation control protein YabA SF1-HH PF16275.5 EPS30323.1 - 1 9.7 8.1 0.17 12.2 1.5 2.4 2 0 0 2 2 2 0 Splicing factor 1 helix-hairpin domain Myb_CC_LHEQLE PF14379.6 EPS30323.1 - 1.1 9.1 10.6 1.8 8.3 4.6 2.7 2 1 0 2 2 2 0 MYB-CC type transfactor, LHEQLE motif HALZ PF02183.18 EPS30323.1 - 1.1 9.5 5.2 8 6.8 0.2 2.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper JIP_LZII PF16471.5 EPS30323.1 - 1.2 9.4 6.3 1.8 8.8 2.5 2.3 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II DUF16 PF01519.16 EPS30323.1 - 2.2 8.8 6.4 0.52 10.8 1.7 2.3 3 0 0 3 3 3 0 Protein of unknown function DUF16 K-box PF01486.17 EPS30323.1 - 2.4 8.4 9.2 8.4 6.6 0.3 2.8 3 0 0 3 3 3 0 K-box region ADIP PF11559.8 EPS30323.1 - 2.7 8.1 11.8 3.2 7.8 0.1 2.7 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding Spc24 PF08286.11 EPS30323.1 - 2.7 8.3 6.7 26 5.1 0.1 2.4 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF4140 PF13600.6 EPS30323.1 - 6.2 7.3 10.3 8 7.0 0.2 3.0 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Csm1_N PF18504.1 EPS30323.1 - 8.7 6.8 9.6 12 6.3 0.1 3.0 3 0 0 3 3 3 0 Csm1 N-terminal domain CGI-121 PF08617.10 EPS30324.1 - 1.6e-53 181.2 0.0 1.8e-53 181.0 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Bax1-I PF01027.20 EPS30325.1 - 5.7e-34 117.8 10.7 8.9e-34 117.1 10.7 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 RRM_1 PF00076.22 EPS30326.1 - 1.1e-16 60.4 0.0 1.6e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EPS30326.1 - 4.6e-05 23.0 0.0 6.5e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EPS30326.1 - 0.013 15.5 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif RRM_occluded PF16842.5 EPS30326.1 - 0.032 14.1 0.0 0.063 13.1 0.0 1.4 1 1 0 1 1 1 0 Occluded RNA-recognition motif IATP PF04568.12 EPS30327.1 - 3.6e-31 107.5 0.3 4e-31 107.3 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP HAUS5 PF14817.6 EPS30327.1 - 0.0085 14.9 0.1 0.0094 14.8 0.1 1.0 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 DUF4140 PF13600.6 EPS30327.1 - 0.073 13.5 1.0 0.15 12.5 0.6 1.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4349 PF14257.6 EPS30327.1 - 0.075 12.5 1.7 0.097 12.1 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) PCSK9_C1 PF18459.1 EPS30328.1 - 0.046 13.9 0.0 0.062 13.5 0.0 1.3 1 0 0 1 1 1 0 Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain 14-3-3 PF00244.20 EPS30329.1 - 3.1e-105 350.6 5.3 3.7e-105 350.4 5.3 1.1 1 0 0 1 1 1 1 14-3-3 protein Orbi_VP5 PF00901.17 EPS30329.1 - 0.074 11.4 2.6 0.12 10.8 2.6 1.3 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 DUF2205 PF10224.9 EPS30331.1 - 9.9e-34 115.2 2.5 9.9e-34 115.2 2.5 1.9 2 0 0 2 2 2 1 Short coiled-coil protein TPR_MLP1_2 PF07926.12 EPS30331.1 - 0.004 17.2 2.8 0.0062 16.6 2.8 1.3 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein bZIP_1 PF00170.21 EPS30331.1 - 0.012 15.7 2.7 0.024 14.7 2.7 1.6 1 0 0 1 1 1 0 bZIP transcription factor YabA PF06156.13 EPS30331.1 - 0.016 15.9 2.4 0.023 15.3 2.4 1.3 1 0 0 1 1 1 0 Initiation control protein YabA DUF2884 PF11101.8 EPS30331.1 - 0.021 14.4 1.4 0.028 13.9 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) DivIC PF04977.15 EPS30331.1 - 0.034 13.9 1.9 0.053 13.3 1.9 1.3 1 0 0 1 1 1 0 Septum formation initiator HALZ PF02183.18 EPS30331.1 - 0.036 14.3 4.4 0.14 12.4 0.3 2.3 1 1 1 2 2 2 0 Homeobox associated leucine zipper DUF5320 PF17253.2 EPS30331.1 - 0.2 12.8 2.7 0.37 11.9 1.6 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5320) Glyco_hydro_76 PF03663.14 EPS30335.1 - 1.1e-21 77.8 0.2 2.2e-14 53.7 0.0 2.8 3 0 0 3 3 3 2 Glycosyl hydrolase family 76 Nsp1_C PF05064.13 EPS30336.1 - 1.3e-42 144.3 2.8 3.1e-42 143.0 2.8 1.6 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.6 EPS30336.1 - 5.2e-05 24.0 33.3 5.2e-05 24.0 33.3 6.3 1 1 3 4 4 3 3 Nucleoporin FG repeat region Laminin_II PF06009.12 EPS30336.1 - 0.15 12.1 10.8 3 7.9 3.2 2.6 1 1 2 3 3 3 0 Laminin Domain II DUF1664 PF07889.12 EPS30336.1 - 0.15 12.1 7.1 0.51 10.4 0.7 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) IFT57 PF10498.9 EPS30336.1 - 0.16 10.9 9.7 0.046 12.7 2.2 2.0 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 ParB PF08775.10 EPS30336.1 - 0.16 12.4 3.2 0.082 13.4 0.6 1.8 2 0 0 2 2 2 0 ParB family DUF4200 PF13863.6 EPS30336.1 - 0.63 10.5 10.7 0.61 10.5 3.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF948 PF06103.11 EPS30336.1 - 0.77 10.1 6.2 1.4 9.2 1.1 3.2 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) AAA_13 PF13166.6 EPS30336.1 - 1.1 7.8 6.6 2.2 6.8 6.5 1.4 1 1 0 1 1 1 0 AAA domain TACC_C PF05010.14 EPS30336.1 - 2.1 8.1 9.5 0.53 10.0 3.8 2.1 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal CK2S PF15011.6 EPS30336.1 - 2.3 8.1 4.9 1.3e+02 2.4 4.9 2.5 1 1 0 1 1 1 0 Casein Kinase 2 substrate DUF3450 PF11932.8 EPS30336.1 - 2.7 7.2 12.7 1.6 8.0 4.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) MscS_porin PF12795.7 EPS30336.1 - 3.1 7.3 11.2 5.3 6.5 1.4 2.2 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain FlaC_arch PF05377.11 EPS30336.1 - 3.6 8.1 4.0 3.8 8.0 0.6 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Prominin PF05478.11 EPS30336.1 - 3.6 5.4 3.9 4.2 5.2 2.7 1.4 1 1 0 1 1 1 0 Prominin DUF4407 PF14362.6 EPS30336.1 - 3.8 6.8 6.6 6.8 6.0 6.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF16 PF01519.16 EPS30336.1 - 4.8 7.7 8.3 18 5.9 5.0 2.6 1 1 2 3 3 3 0 Protein of unknown function DUF16 Snapin_Pallidin PF14712.6 EPS30336.1 - 5.3 7.5 5.0 3.5 8.1 0.9 2.4 1 1 1 2 2 2 0 Snapin/Pallidin HIP1_clath_bdg PF16515.5 EPS30336.1 - 5.5 7.7 10.3 19 5.9 3.6 2.6 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 V-SNARE PF05008.15 EPS30336.1 - 7.3 7.0 9.1 2.6 8.5 0.5 3.1 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus LMBR1 PF04791.16 EPS30336.1 - 7.4 5.4 6.6 0.68 8.8 0.4 1.9 1 1 1 2 2 2 0 LMBR1-like membrane protein DUF5102 PF17104.5 EPS30337.1 - 2.1e-105 352.9 1.1 2.1e-105 352.9 1.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF5102) zf-MIZ PF02891.20 EPS30338.1 - 9.4e-12 44.5 0.2 1.9e-11 43.5 0.2 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 EPS30338.1 - 0.024 14.4 0.2 0.083 12.7 0.2 2.0 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit YccJ PF13993.6 EPS30338.1 - 0.11 12.9 0.1 0.25 11.7 0.1 1.6 1 0 0 1 1 1 0 YccJ-like protein SH3_9 PF14604.6 EPS30339.1 - 3.3e-14 52.5 0.1 6.6e-14 51.5 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.29 EPS30339.1 - 4.8e-13 49.5 0.0 1.6e-12 47.8 0.0 1.9 1 1 0 1 1 1 1 PH domain SH3_1 PF00018.28 EPS30339.1 - 1.3e-09 37.5 0.1 2.8e-09 36.4 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SAM_2 PF07647.17 EPS30339.1 - 2.8e-08 33.8 0.1 4.7e-08 33.0 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 EPS30339.1 - 7.6e-06 25.5 0.1 1.8e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.30 EPS30339.1 - 0.0032 17.9 0.1 0.0059 17.0 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.6 EPS30339.1 - 0.0043 17.5 0.0 0.01 16.3 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 EPS30339.1 - 0.13 12.6 0.0 0.36 11.1 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain Ribosomal_L14 PF00238.19 EPS30341.1 - 2.2e-34 118.2 0.0 2.6e-34 117.9 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Endonuc-FokI_C PF09254.11 EPS30341.1 - 0.039 13.2 0.0 0.055 12.7 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease FokI, C terminal Hist_deacetyl PF00850.19 EPS30342.1 - 1.2e-82 277.8 0.0 2.2e-82 277.0 0.0 1.4 2 0 0 2 2 2 1 Histone deacetylase domain JAB PF01398.21 EPS30343.1 - 1.1e-33 115.6 0.0 2.5e-33 114.5 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EPS30343.1 - 1.9e-12 47.6 1.1 3.3e-12 46.8 1.1 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 EPS30343.1 - 1.4e-07 31.3 0.0 4.6e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 EPS30343.1 - 0.045 13.8 0.2 0.23 11.5 0.0 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0172) F-box-like_2 PF13013.6 EPS30344.1 - 0.026 14.5 0.1 0.052 13.5 0.1 1.5 1 1 0 1 1 1 0 F-box-like domain NIF PF03031.18 EPS30345.1 - 1.2e-41 142.1 0.1 1.7e-41 141.6 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Mucin PF01456.17 EPS30345.1 - 7.3 6.6 7.7 12 5.9 7.7 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Fungal_trans PF04082.18 EPS30346.1 - 1e-15 57.5 0.0 1.8e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS30346.1 - 9.7e-07 28.8 6.8 2.1e-06 27.7 6.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.7 EPS30347.1 - 0.0061 16.4 0.3 0.013 15.3 0.3 1.6 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 EPS30347.1 - 0.01 16.1 0.0 5.2 7.4 0.0 3.6 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain GRDP-like PF07173.12 EPS30348.1 - 1.4e-16 61.4 2.0 2.1e-14 54.4 0.3 2.5 2 0 0 2 2 2 2 Glycine-rich domain-containing protein-like Fungal_trans PF04082.18 EPS30349.1 - 2.3e-09 36.7 0.3 3.7e-09 36.0 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS30349.1 - 3.8e-06 26.9 10.7 3.8e-06 26.9 10.7 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 EPS30353.1 - 1.3e-68 231.3 0.0 2.1e-68 230.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS30353.1 - 1.2e-32 113.2 0.0 3.8e-31 108.3 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EPS30353.1 - 0.012 14.9 0.2 4.2 6.6 0.0 2.5 2 0 0 2 2 2 0 Kinase-like Peptidase_S10 PF00450.22 EPS30354.1 - 2.6e-90 303.8 0.6 3.4e-90 303.4 0.6 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase MFS_1 PF07690.16 EPS30357.1 - 2.3e-29 102.4 46.9 2.3e-29 102.4 46.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS30357.1 - 1.4e-06 27.5 11.3 1.4e-06 27.5 11.3 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EPS30358.1 - 4.9e-30 104.7 38.1 3.7e-19 68.9 26.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS30358.1 - 1.3e-21 77.0 18.2 2.9e-21 75.9 18.2 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 EPS30358.1 - 0.00088 18.2 4.5 0.0033 16.4 3.1 2.3 2 1 0 2 2 2 1 MFS_1 like family Nucleoside_tran PF01733.18 EPS30358.1 - 0.075 12.4 5.0 3.2 7.0 0.1 2.5 2 0 0 2 2 2 0 Nucleoside transporter CN_hydrolase PF00795.22 EPS30359.1 - 2e-36 125.7 0.0 2.3e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Vac17 PF17321.2 EPS30361.1 - 0.84 9.0 7.4 1.1 8.6 6.9 1.6 1 1 0 1 1 1 0 Vacuole-related protein 17 HAMP PF00672.25 EPS30362.1 - 2e-43 146.5 15.7 1.3e-08 35.0 0.4 7.3 6 0 0 6 6 6 5 HAMP domain HATPase_c PF02518.26 EPS30362.1 - 9.5e-33 113.0 0.2 3.6e-32 111.2 0.2 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EPS30362.1 - 3.6e-26 91.5 0.4 1.6e-25 89.4 0.4 2.3 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EPS30362.1 - 1.1e-16 60.6 3.8 3.1e-16 59.1 0.2 3.7 4 0 0 4 4 4 1 His Kinase A (phospho-acceptor) domain APG17 PF04108.12 EPS30362.1 - 5.1e-13 48.9 5.8 0.0073 15.5 0.2 5.6 1 1 2 4 4 4 4 Autophagy protein Apg17 Syntaxin_2 PF14523.6 EPS30362.1 - 1.7e-05 25.1 19.6 1.1 9.6 0.1 7.1 3 2 2 6 6 6 2 Syntaxin-like protein DUF4279 PF14106.6 EPS30362.1 - 0.00048 20.3 0.5 8.3 6.7 0.0 5.4 6 1 0 6 6 5 1 Domain of unknown function (DUF4279) DUF1843 PF08898.10 EPS30362.1 - 0.00062 20.2 7.4 16 6.1 0.1 6.6 6 1 0 6 6 6 0 Domain of unknown function (DUF1843) DUF948 PF06103.11 EPS30362.1 - 0.0046 17.2 56.5 1.1 9.5 0.2 9.9 4 2 2 6 6 6 2 Bacterial protein of unknown function (DUF948) Gp-FAR-1 PF05823.12 EPS30362.1 - 0.0084 16.5 4.7 21 5.4 0.1 5.0 1 1 3 5 5 5 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Fib_alpha PF08702.10 EPS30362.1 - 0.03 14.5 34.3 0.48 10.6 0.5 7.3 6 1 1 7 7 7 0 Fibrinogen alpha/beta chain family DUF3829 PF12889.7 EPS30362.1 - 0.032 13.7 14.3 0.3 10.5 0.7 4.9 3 3 2 5 5 5 0 Protein of unknown function (DUF3829) SpoIIID PF12116.8 EPS30362.1 - 0.032 14.3 4.6 24 5.1 0.0 5.2 5 0 0 5 5 5 0 Stage III sporulation protein D NOD PF06816.13 EPS30362.1 - 0.051 13.2 0.0 6.5 6.5 0.0 2.7 2 0 0 2 2 2 0 NOTCH protein IcmF_C PF06744.12 EPS30362.1 - 0.082 12.5 0.1 0.31 10.6 0.1 2.0 1 0 0 1 1 1 0 Type VI secretion protein IcmF C-terminal DUF4795 PF16043.5 EPS30362.1 - 0.084 12.5 24.9 0.22 11.1 2.9 4.9 1 1 4 5 5 5 0 Domain of unknown function (DUF4795) CMD PF02627.20 EPS30362.1 - 0.12 12.4 1.1 17 5.6 0.0 4.1 5 0 0 5 5 4 0 Carboxymuconolactone decarboxylase family BORCS6 PF10157.9 EPS30362.1 - 0.53 10.5 14.6 6 7.1 0.1 5.7 3 2 1 5 5 5 0 BLOC-1-related complex sub-unit 6 WXG100 PF06013.12 EPS30362.1 - 0.56 10.5 28.3 2 8.7 0.3 8.2 5 3 4 9 9 9 0 Proteins of 100 residues with WXG ImcF-related_N PF14331.6 EPS30362.1 - 3.7 6.8 7.1 5.7 6.2 0.2 4.2 4 1 3 7 7 7 0 ImcF-related N-terminal domain Mer2 PF09074.10 EPS30362.1 - 5.1 6.8 37.7 3.3 7.5 3.6 5.9 3 1 3 6 6 6 0 Mer2 tRNA-synt_2d PF01409.20 EPS30363.1 - 1.1e-88 296.9 0.0 1.4e-88 296.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 EPS30363.1 - 1.4e-15 57.3 0.4 1.4e-15 57.3 0.4 1.8 2 0 0 2 2 2 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 EPS30363.1 - 1.6e-08 34.2 0.0 0.00028 20.4 0.0 2.4 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain PheRS_DBD2 PF18554.1 EPS30363.1 - 0.00039 20.3 1.2 0.0026 17.7 1.8 2.2 2 0 0 2 2 2 1 PheRS DNA binding domain 2 tRNA-synt_2 PF00152.20 EPS30363.1 - 0.00041 19.5 0.1 0.0097 15.0 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 EPS30363.1 - 0.045 13.7 0.0 0.087 12.8 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) Ribosomal_S21e PF01249.18 EPS30364.1 - 9.3e-42 141.0 0.1 1e-41 140.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e NUDIX PF00293.28 EPS30365.1 - 1.5e-06 28.2 0.0 4.2e-06 26.8 0.0 1.9 1 1 0 1 1 1 1 NUDIX domain PD-C2-AF1 PF09310.10 EPS30365.1 - 0.073 12.5 0.3 1.6 8.0 0.1 2.3 2 1 0 2 2 2 0 POU domain, class 2, associating factor 1 GHL6 PF14871.6 EPS30365.1 - 0.14 12.3 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 IMPDH PF00478.25 EPS30366.1 - 1.7e-128 428.5 3.1 2.1e-128 428.2 3.1 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 EPS30366.1 - 2.3e-17 63.2 0.0 4.9e-09 36.5 0.0 2.5 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 EPS30366.1 - 1e-06 28.0 2.0 3.9e-06 26.1 0.9 2.1 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 EPS30366.1 - 0.00011 21.7 9.6 0.015 14.7 7.2 2.5 2 1 0 2 2 2 2 Nitronate monooxygenase His_biosynth PF00977.21 EPS30366.1 - 0.0011 18.5 1.4 0.0035 16.9 1.4 1.7 1 1 0 1 1 1 1 Histidine biosynthesis protein Aldolase PF01081.19 EPS30366.1 - 0.01 15.3 0.6 0.091 12.2 0.1 2.3 1 1 1 2 2 2 0 KDPG and KHG aldolase DUF952 PF06108.12 EPS30367.1 - 3.2e-20 71.9 0.0 4e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) RasGAP_C PF03836.15 EPS30368.1 - 2.1e-47 160.7 4.0 2.1e-47 160.7 4.0 2.9 3 0 0 3 3 3 1 RasGAP C-terminus RasGAP PF00616.19 EPS30368.1 - 6e-45 153.5 0.0 1.8e-44 152.0 0.0 1.9 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CH PF00307.31 EPS30368.1 - 9e-12 45.1 0.0 3.1e-11 43.4 0.0 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain IQ PF00612.27 EPS30368.1 - 1.7e-10 39.7 50.9 0.54 10.2 0.1 14.6 15 0 0 15 15 15 6 IQ calmodulin-binding motif CAMSAP_CH PF11971.8 EPS30368.1 - 0.093 12.6 0.0 0.3 11.0 0.0 1.8 1 0 0 1 1 1 0 CAMSAP CH domain MCM_lid PF17855.1 EPS30368.1 - 0.66 10.4 5.2 0.35 11.3 0.9 2.9 3 0 0 3 3 3 0 MCM AAA-lid domain ENTH PF01417.20 EPS30369.1 - 4e-44 149.6 0.1 5.6e-44 149.2 0.1 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 EPS30369.1 - 0.00022 20.3 0.0 0.00032 19.8 0.0 1.2 1 0 0 1 1 1 1 ANTH domain SH3_9 PF14604.6 EPS30370.1 - 6.7e-11 41.9 0.1 1.3e-10 40.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EPS30370.1 - 1e-10 41.0 0.0 1.7e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EPS30370.1 - 1.6e-08 34.1 0.0 2.7e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain RHINO PF15319.6 EPS30372.1 - 0.028 14.5 3.4 0.05 13.6 3.4 1.4 1 0 0 1 1 1 0 RAD9, RAD1, HUS1-interacting nuclear orphan protein HMG-CoA_red PF00368.18 EPS30373.1 - 1.6e-137 458.5 4.3 2.1e-137 458.1 4.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 EPS30373.1 - 1.6e-55 187.2 0.2 2.9e-55 186.4 0.2 1.4 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 EPS30373.1 - 3.2e-12 46.5 2.8 1.3e-11 44.6 2.8 2.0 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.18 EPS30373.1 - 0.00039 18.6 1.8 0.00059 18.1 1.8 1.1 1 0 0 1 1 1 1 Patched family GIT_SHD PF08518.11 EPS30374.1 - 2e-24 84.9 9.3 5.7e-14 51.4 1.4 2.7 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT GIT1_C PF12205.8 EPS30374.1 - 0.0013 18.8 0.3 0.0013 18.8 0.3 3.1 3 2 2 5 5 5 1 G protein-coupled receptor kinase-interacting protein 1 C term AAA_32 PF13654.6 EPS30374.1 - 0.068 11.9 11.5 0.19 10.4 11.5 1.8 1 0 0 1 1 1 0 AAA domain DUF3719 PF12516.8 EPS30374.1 - 0.14 11.9 0.5 0.65 9.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3719) DUF327 PF03885.13 EPS30374.1 - 0.14 12.1 0.0 0.14 12.1 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF327) DUF4407 PF14362.6 EPS30374.1 - 1.2 8.4 16.8 6.8 5.9 16.7 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) THP2 PF09432.10 EPS30374.1 - 3 7.9 8.3 0.45 10.6 2.6 2.4 1 1 1 2 2 2 0 Tho complex subunit THP2 GrpE PF01025.19 EPS30374.1 - 3.7 7.2 23.2 81 2.8 3.8 4.5 2 1 1 3 3 3 0 GrpE BRE1 PF08647.11 EPS30374.1 - 6.2 7.0 25.4 6.6 6.9 10.0 4.7 2 1 2 4 4 4 0 BRE1 E3 ubiquitin ligase SlyX PF04102.12 EPS30374.1 - 7.2 7.3 27.3 1.1 9.9 2.3 5.2 4 1 1 5 5 5 0 SlyX Glyco_transf_8 PF01501.20 EPS30375.1 - 1.4e-11 44.5 0.0 2.4e-11 43.7 0.0 1.3 1 1 0 1 1 1 1 Glycosyl transferase family 8 Pro_isomerase PF00160.21 EPS30376.1 - 1.4e-44 152.1 0.0 1.7e-44 151.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ctr PF04145.15 EPS30377.1 - 3.5e-40 138.0 0.0 4.6e-40 137.6 0.0 1.2 1 0 0 1 1 1 1 Ctr copper transporter family Oxidored_q3 PF00499.20 EPS30377.1 - 0.023 14.4 2.7 0.099 12.4 3.2 1.7 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 LapA_dom PF06305.11 EPS30377.1 - 0.18 11.6 1.0 0.4 10.5 0.2 1.9 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain RNase_PH PF01138.21 EPS30378.1 - 2e-32 112.5 0.5 9.7e-32 110.2 0.3 1.9 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 SNF2_N PF00176.23 EPS30379.1 - 8e-51 172.8 0.2 1.8e-50 171.7 0.2 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.6 EPS30379.1 - 9.5e-25 86.5 0.0 3.3e-24 84.8 0.0 2.1 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.31 EPS30379.1 - 3.9e-21 75.5 0.0 1.1e-18 67.6 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPS30379.1 - 2.7e-08 34.0 0.0 1.4e-07 31.7 0.0 2.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EPS30379.1 - 3.1e-07 29.8 0.0 8.8e-07 28.4 0.0 1.7 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Ssu72 PF04722.13 EPS30380.1 - 2e-82 275.4 0.0 2.3e-82 275.2 0.0 1.1 1 0 0 1 1 1 1 Ssu72-like protein Mito_fiss_reg PF05308.11 EPS30380.1 - 2 8.4 5.9 3.2 7.8 5.9 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Isochorismatase PF00857.20 EPS30381.1 - 8.7e-21 74.9 0.2 1.8e-20 73.8 0.2 1.5 1 1 0 1 1 1 1 Isochorismatase family DUF3605 PF12239.8 EPS30382.1 - 9e-57 191.7 1.3 1.3e-56 191.1 1.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) Oxysterol_BP PF01237.18 EPS30383.1 - 6.4e-91 305.0 0.0 3.8e-88 295.9 0.0 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein Hist_deacetyl PF00850.19 EPS30384.1 - 5.7e-77 259.2 0.1 7.2e-77 258.9 0.1 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Zn_clus PF00172.18 EPS30385.1 - 3.5e-09 36.6 11.5 7.7e-09 35.5 11.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PEP_mutase PF13714.6 EPS30386.1 - 6.2e-48 163.3 0.5 7.2e-48 163.1 0.5 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 EPS30386.1 - 1.9e-19 69.6 0.2 2.5e-19 69.2 0.2 1.1 1 0 0 1 1 1 1 Isocitrate lyase family DUF3433 PF11915.8 EPS30389.1 - 1.3e-30 105.7 9.8 8.3e-20 71.1 2.3 4.0 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) Tom37 PF10568.9 EPS30390.1 - 5.5e-41 139.8 0.0 7.3e-40 136.2 0.0 2.2 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_C_6 PF17171.4 EPS30390.1 - 1.8e-08 34.0 0.0 8e-08 32.0 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EPS30390.1 - 5.1e-07 30.3 0.0 4.2e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain Lipase_GDSL PF00657.22 EPS30391.1 - 4.1e-15 56.3 0.0 5.3e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.6 EPS30391.1 - 1.3e-07 32.1 2.5 8.3e-07 29.6 2.5 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family PRP9_N PF16958.5 EPS30395.1 - 0.0067 16.5 0.2 0.016 15.2 0.0 1.7 2 0 0 2 2 2 1 Pre-mRNA-splicing factor PRP9 N-terminus Saw1 PF11561.8 EPS30395.1 - 0.097 12.2 0.1 0.35 10.4 0.1 1.8 2 0 0 2 2 2 0 Single strand annealing-weakened 1 Zip PF02535.22 EPS30396.1 - 1.3e-65 221.9 13.8 1.4e-65 221.7 13.8 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Sugar_tr PF00083.24 EPS30397.1 - 1.1e-52 179.5 27.7 2.7e-51 174.8 27.7 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS30397.1 - 2.2e-15 56.5 38.1 2.5e-07 30.0 17.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EPS30397.1 - 0.0064 15.1 1.1 0.0064 15.1 1.1 3.2 2 2 1 3 3 3 3 MFS/sugar transport protein DMT_YdcZ PF04657.13 EPS30397.1 - 0.055 13.8 19.6 0.13 12.6 2.9 3.5 3 0 0 3 3 3 0 Putative inner membrane exporter, YdcZ FKBP_C PF00254.28 EPS30398.1 - 1.2e-33 115.3 0.0 1.4e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Cyt-b5 PF00173.28 EPS30399.1 - 5.8e-14 52.0 0.0 9e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PP2C PF00481.21 EPS30400.1 - 1.8e-42 145.8 0.0 2e-42 145.6 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EPS30400.1 - 5.9e-10 39.1 0.0 2.1e-09 37.3 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EPS30400.1 - 0.0035 17.3 0.0 0.82 9.6 0.0 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) MIT PF04212.18 EPS30401.1 - 0.065 13.3 0.0 0.092 12.8 0.0 1.2 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain FmdA_AmdA PF03069.15 EPS30402.1 - 3.9e-55 187.2 0.0 3e-31 108.6 0.0 2.2 1 1 1 2 2 2 2 Acetamidase/Formamidase family UvrD-helicase PF00580.21 EPS30403.1 - 4.7e-63 213.6 0.1 1.2e-61 209.0 0.1 2.2 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 EPS30403.1 - 7.5e-57 193.3 0.0 1.5e-53 182.4 0.0 2.4 2 1 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 EPS30403.1 - 5.7e-31 107.8 0.0 1.2e-30 106.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 EPS30403.1 - 1.6e-13 50.2 0.0 3.4e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 EPS30403.1 - 2.6e-08 33.8 0.9 0.00049 19.9 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_12 PF13087.6 EPS30403.1 - 1.1e-05 25.2 0.0 0.00094 18.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 EPS30403.1 - 2.7e-05 24.0 0.4 0.094 12.4 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 EPS30403.1 - 0.0016 18.3 0.1 0.0076 16.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EPS30403.1 - 0.018 15.3 1.0 1.4 9.2 1.0 2.7 1 1 0 1 1 1 0 AAA domain PolyA_pol_RNAbd PF12627.7 EPS30403.1 - 0.14 11.9 0.0 0.42 10.4 0.0 1.7 1 0 0 1 1 1 0 Probable RNA and SrmB- binding site of polymerase A ATPgrasp_Ter PF15632.6 EPS30403.1 - 0.16 11.7 0.1 0.35 10.6 0.1 1.4 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Cyclin_N PF00134.23 EPS30406.1 - 1.3e-34 118.7 0.2 3e-34 117.5 0.2 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EPS30406.1 - 2.1e-11 44.0 0.3 7.5e-11 42.2 0.3 2.0 1 0 0 1 1 1 1 Cyclin, C-terminal domain WD40 PF00400.32 EPS30410.1 - 1.9e-11 44.3 0.4 0.096 13.6 0.0 8.2 9 0 0 9 9 9 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS30410.1 - 4.4e-07 30.1 0.2 0.81 10.0 0.0 6.3 4 2 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EPS30410.1 - 5.4e-06 26.2 0.1 0.11 12.1 0.0 3.7 3 1 1 4 4 4 3 PQQ-like domain Ge1_WD40 PF16529.5 EPS30410.1 - 0.084 11.8 0.0 0.95 8.4 0.0 2.7 4 0 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EPS30410.1 - 0.1 11.2 0.0 4.6 5.8 0.0 2.5 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Rxt3 PF08642.10 EPS30410.1 - 0.47 11.2 2.3 0.37 11.6 0.1 1.9 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 TAT_ubiq PF07706.12 EPS30410.1 - 0.64 10.3 3.9 0.68 10.2 0.2 2.8 3 0 0 3 3 3 0 Aminotransferase ubiquitination site Yippee-Mis18 PF03226.14 EPS30411.1 - 8e-19 67.8 0.4 8.9e-19 67.6 0.4 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 EPS30411.1 - 0.0023 18.1 0.5 0.0034 17.6 0.5 1.2 1 0 0 1 1 1 1 C-terminal domain of RIG-I DUF2039 PF10217.9 EPS30411.1 - 0.021 15.2 0.6 0.1 12.9 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) Evr1_Alr PF04777.13 EPS30411.1 - 0.11 13.0 0.6 1.4 9.4 0.1 2.1 1 1 1 2 2 2 0 Erv1 / Alr family ADH_N PF08240.12 EPS30412.1 - 3.6e-30 104.0 2.1 6e-30 103.3 2.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPS30412.1 - 1.6e-16 60.5 0.0 3e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EPS30412.1 - 1e-05 25.2 0.0 1.9e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EPS30412.1 - 0.0029 18.7 0.0 0.0068 17.5 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EPS30412.1 - 0.0052 16.1 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 EPS30412.1 - 0.032 14.5 0.0 0.06 13.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain KH_1 PF00013.29 EPS30413.1 - 2.7e-41 139.2 7.1 4.2e-16 58.5 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EPS30413.1 - 9.7e-09 34.9 10.4 0.0045 16.8 0.9 3.4 3 1 0 3 3 3 3 KH domain KH_4 PF13083.6 EPS30413.1 - 5.4e-08 32.6 3.5 0.047 13.6 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 EPS30413.1 - 0.00038 20.5 6.2 0.33 11.1 0.1 3.3 3 0 0 3 3 3 2 NusA-like KH domain MOEP19 PF16005.5 EPS30413.1 - 0.025 14.6 0.0 30 4.7 0.0 3.1 3 0 0 3 3 3 0 KH-like RNA-binding domain DSPc PF00782.20 EPS30418.1 - 3.3e-23 81.9 0.0 1.9e-20 73.0 0.0 2.2 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Methyltransf_31 PF13847.6 EPS30419.1 - 1.5e-14 54.1 0.0 2.2e-07 30.8 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 EPS30419.1 - 4.6e-11 42.8 0.0 6.9e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS30419.1 - 8.1e-09 36.0 0.0 0.00011 22.8 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 EPS30419.1 - 9.3e-08 32.7 0.0 4.4e-06 27.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPS30419.1 - 2.7e-06 28.0 0.1 1.2e-05 26.0 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EPS30419.1 - 0.012 15.2 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain MetW PF07021.12 EPS30419.1 - 0.024 14.2 0.0 0.073 12.7 0.0 1.7 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 EPS30419.1 - 0.045 13.7 0.0 0.068 13.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 EPS30419.1 - 0.19 11.0 0.0 0.98 8.7 0.0 1.8 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Caskin-Pro-rich PF16907.5 EPS30419.1 - 0.22 12.0 0.2 0.22 12.0 0.2 2.2 2 0 0 2 2 2 0 Proline rich region of Caskin proteins FAM176 PF14851.6 EPS30419.1 - 0.78 9.4 4.5 0.67 9.6 1.3 2.0 2 0 0 2 2 2 0 FAM176 family RXT2_N PF08595.11 EPS30419.1 - 4.3 7.3 5.9 0.92 9.5 0.9 1.9 2 0 0 2 2 2 0 RXT2-like, N-terminal zf-C2H2 PF00096.26 EPS30420.1 - 0.37 11.3 2.8 1.1 9.8 2.8 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type Aegerolysin PF06355.13 EPS30422.1 - 1.7e-16 60.5 0.0 3.2e-08 33.7 0.0 2.1 2 0 0 2 2 2 2 Aegerolysin CDH-cyt PF16010.5 EPS30423.1 - 8.5e-22 77.7 0.3 1.4e-21 77.0 0.3 1.3 1 0 0 1 1 1 1 Cytochrome domain of cellobiose dehydrogenase Cytochrom_B561 PF03188.16 EPS30423.1 - 2.6e-10 40.6 9.4 5.4e-10 39.5 9.4 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 EPS30423.1 - 1.5e-07 31.2 3.1 1.7e-07 31.0 1.7 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) DUF998 PF06197.13 EPS30423.1 - 0.0026 17.4 11.5 0.0098 15.5 1.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF998) DUF4079 PF13301.6 EPS30423.1 - 0.024 14.8 9.1 0.08 13.1 3.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) MHYT PF03707.16 EPS30423.1 - 2.2 8.5 12.1 4.2 7.6 0.0 4.3 3 1 2 5 5 5 0 Bacterial signalling protein N terminal repeat VSP PF03302.13 EPS30423.1 - 3.4 6.4 5.4 6.8 5.4 5.4 1.4 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF1129 PF06570.11 EPS30423.1 - 5.2 6.5 7.3 2.7 7.4 4.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) Ribosomal_L24e PF01246.20 EPS30424.1 - 8.8e-28 96.3 8.1 9e-28 96.3 6.0 2.1 2 0 0 2 2 2 1 Ribosomal protein L24e Pam16 PF03656.13 EPS30425.1 - 7.5e-08 32.4 0.0 8.3e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.31 EPS30425.1 - 5.6e-05 23.2 0.1 9e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Fungal_trans PF04082.18 EPS30427.1 - 2.2e-24 85.9 0.0 5.7e-24 84.6 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS30427.1 - 8.4e-10 38.6 13.1 1.5e-09 37.8 13.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OPT PF03169.15 EPS30428.1 - 1.1e-170 569.3 51.4 1.3e-170 569.1 51.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Peptidase_M41 PF01434.18 EPS30429.1 - 1.7e-66 223.7 0.0 4.7e-66 222.3 0.0 1.8 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EPS30429.1 - 3e-43 147.4 0.0 6.3e-43 146.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.15 EPS30429.1 - 2.6e-13 50.3 1.2 7.7e-13 48.8 0.0 2.2 2 0 0 2 2 2 1 FtsH Extracellular AAA_lid_3 PF17862.1 EPS30429.1 - 1.4e-12 47.2 0.2 3.3e-12 46.0 0.2 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EPS30429.1 - 0.0013 18.7 0.0 0.0044 17.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EPS30429.1 - 0.0028 18.1 0.2 0.15 12.4 0.2 2.8 1 1 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 EPS30429.1 - 0.0096 15.2 0.1 0.021 14.0 0.1 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 EPS30429.1 - 0.012 15.9 0.1 1.1 9.5 0.1 2.9 3 0 0 3 3 3 0 AAA domain RuvB_N PF05496.12 EPS30429.1 - 0.014 15.2 0.0 0.037 13.8 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain DDHD PF02862.17 EPS30429.1 - 0.045 13.9 1.1 0.078 13.1 1.1 1.3 1 0 0 1 1 1 0 DDHD domain IstB_IS21 PF01695.17 EPS30429.1 - 0.076 12.7 0.0 0.21 11.3 0.0 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.14 EPS30429.1 - 0.19 11.8 2.4 0.21 11.7 0.0 2.2 2 1 0 2 2 1 0 AAA domain (Cdc48 subfamily) AAA_11 PF13086.6 EPS30429.1 - 0.41 10.4 8.6 8.4 6.1 0.1 2.3 2 0 0 2 2 2 0 AAA domain DUF3381 PF11861.8 EPS30429.1 - 0.58 9.9 13.6 0.14 11.9 10.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) CCDC53 PF10152.9 EPS30429.1 - 0.59 10.5 7.9 8.6 6.8 5.7 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF5327 PF17261.2 EPS30429.1 - 0.66 10.8 7.5 1.4 9.7 7.5 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5327) Presenilin PF01080.17 EPS30429.1 - 5.2 5.7 5.7 7.5 5.2 5.7 1.2 1 0 0 1 1 1 0 Presenilin DUF908 PF06012.12 EPS30429.1 - 7.9 5.8 6.1 12 5.2 6.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) DUF1295 PF06966.12 EPS30430.1 - 6e-43 147.1 11.3 8.2e-43 146.6 11.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 EPS30430.1 - 0.065 13.7 0.0 0.065 13.7 0.0 3.1 3 0 0 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Topoisom_bac PF01131.20 EPS30431.1 - 1.3e-101 340.6 0.0 1.6e-101 340.3 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 EPS30431.1 - 6.2e-19 68.1 0.0 4.7e-18 65.3 0.0 2.3 2 0 0 2 2 2 1 Toprim domain SIP1 PF04938.12 EPS30434.1 - 0.0004 20.2 0.0 0.45 10.2 0.0 2.4 2 0 0 2 2 2 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) PX PF00787.24 EPS30435.1 - 8.5e-16 57.9 0.0 1.7e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 PX domain T3SS_needle_E PF08988.10 EPS30435.1 - 0.25 11.5 0.1 0.25 11.5 0.1 2.7 3 0 0 3 3 3 0 Type III secretion system, cytoplasmic E component of needle Ku_PK_bind PF08785.11 EPS30436.1 - 7.4e-35 119.7 0.0 2.1e-34 118.2 0.0 1.8 1 0 0 1 1 1 1 Ku C terminal domain like Ku PF02735.16 EPS30436.1 - 4.2e-32 111.5 0.0 9.8e-32 110.3 0.0 1.6 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 EPS30436.1 - 1.2e-11 44.8 0.0 2e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain VWA PF00092.28 EPS30436.1 - 0.0002 21.7 0.1 0.0019 18.5 0.1 2.5 3 0 0 3 3 3 1 von Willebrand factor type A domain DUF4149 PF13664.6 EPS30437.1 - 1.2e-28 99.4 3.3 1.9e-28 98.8 2.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) DUF1772 PF08592.11 EPS30437.1 - 0.016 15.5 0.4 0.021 15.1 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) DUF2615 PF11027.8 EPS30437.1 - 0.052 13.7 0.0 0.084 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) tRNA-synt_2 PF00152.20 EPS30438.1 - 4.3e-72 242.9 0.1 5.8e-72 242.4 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EPS30438.1 - 4.2e-06 26.6 0.1 7.3e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Hydrolase_6 PF13344.6 EPS30439.1 - 8.6e-25 86.8 0.0 1.7e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EPS30439.1 - 1.1e-17 63.8 0.0 4.3e-17 62.0 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 EPS30439.1 - 1e-05 25.9 0.0 0.023 15.0 0.1 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EPS30439.1 - 0.039 14.1 0.0 10 6.2 0.0 2.5 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase HAD PF12710.7 EPS30439.1 - 0.069 13.5 0.0 1.5 9.2 0.0 2.8 3 1 1 4 4 4 0 haloacid dehalogenase-like hydrolase DAGK_cat PF00781.24 EPS30439.1 - 0.16 11.6 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain F-box-like PF12937.7 EPS30440.1 - 3.7e-06 26.7 0.9 9e-06 25.5 0.1 2.1 2 0 0 2 2 2 1 F-box-like Adaptin_N PF01602.20 EPS30441.1 - 2.7e-114 382.6 0.4 3.6e-114 382.2 0.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 EPS30441.1 - 5.2e-58 195.5 1.6 1.3e-57 194.2 1.6 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 EPS30441.1 - 1e-34 119.1 0.6 5.3e-34 116.8 0.2 2.5 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 EPS30441.1 - 3.2e-18 65.9 0.7 7.8e-12 45.4 0.0 5.4 4 1 1 5 5 5 3 HEAT repeats Cnd1 PF12717.7 EPS30441.1 - 3.2e-09 37.0 8.1 0.0017 18.4 0.1 5.2 4 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EPS30441.1 - 0.00029 20.8 4.0 1.3 9.4 0.1 5.9 6 0 0 6 6 6 1 HEAT repeat HEAT_PBS PF03130.16 EPS30441.1 - 0.0087 16.6 5.5 5.8 7.9 0.0 5.3 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 EPS30441.1 - 0.83 10.2 3.1 1.4 9.6 0.2 2.9 4 0 0 4 4 4 0 HEAT-like repeat Phosducin PF02114.16 EPS30442.1 - 1.3e-12 47.2 0.1 1.7e-12 46.9 0.1 1.2 1 0 0 1 1 1 1 Phosducin bZIP_1 PF00170.21 EPS30443.1 - 1.4e-09 37.9 10.6 2.4e-09 37.2 10.6 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EPS30443.1 - 0.00036 20.6 11.5 0.00053 20.0 10.8 1.7 1 1 0 1 1 1 1 Basic region leucine zipper PAP1 PF08601.10 EPS30443.1 - 0.0015 18.3 10.1 0.0055 16.5 0.0 2.1 2 0 0 2 2 2 1 Transcription factor PAP1 PGBA_C PF15437.6 EPS30443.1 - 0.0025 18.1 4.5 0.0051 17.1 4.5 1.5 1 0 0 1 1 1 1 Plasminogen-binding protein pgbA C-terminal SHE3 PF17078.5 EPS30443.1 - 0.0031 17.3 4.6 0.0046 16.7 4.6 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 V_ATPase_I PF01496.19 EPS30443.1 - 0.0094 13.9 1.4 0.012 13.6 1.4 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family bZIP_Maf PF03131.17 EPS30443.1 - 0.011 16.3 9.1 0.017 15.6 9.1 1.3 1 0 0 1 1 1 0 bZIP Maf transcription factor MIS13 PF08202.11 EPS30443.1 - 0.025 13.9 5.1 0.034 13.4 5.1 1.1 1 0 0 1 1 1 0 Mis12-Mtw1 protein family YabA PF06156.13 EPS30443.1 - 0.052 14.2 1.4 0.079 13.6 0.8 1.5 1 1 0 1 1 1 0 Initiation control protein YabA DivIC PF04977.15 EPS30443.1 - 0.071 12.9 3.3 0.079 12.7 2.4 1.5 1 1 0 1 1 1 0 Septum formation initiator PGA2 PF07543.12 EPS30443.1 - 0.13 12.3 4.3 0.22 11.5 4.3 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 Adaptin_binding PF10199.9 EPS30443.1 - 0.13 12.8 7.2 0.22 12.1 7.2 1.3 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 TSC22 PF01166.18 EPS30443.1 - 0.18 12.1 1.2 2.3 8.6 0.3 2.4 1 1 1 2 2 2 0 TSC-22/dip/bun family FlaC_arch PF05377.11 EPS30443.1 - 0.19 12.2 0.3 0.33 11.4 0.3 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) PSI_PsaF PF02507.15 EPS30443.1 - 0.29 10.9 0.9 0.5 10.2 0.9 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit III ADIP PF11559.8 EPS30443.1 - 0.65 10.1 12.0 0.082 13.0 4.0 1.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding GvpL_GvpF PF06386.11 EPS30443.1 - 0.72 9.7 5.8 1.1 9.1 5.8 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF5094 PF17015.5 EPS30443.1 - 0.75 9.9 8.4 1.1 9.3 8.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) UPF0242 PF06785.11 EPS30443.1 - 1.7 8.7 5.7 2.6 8.1 5.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ZapB PF06005.12 EPS30443.1 - 2.4 8.7 10.1 0.093 13.2 3.2 1.9 1 1 1 2 2 2 0 Cell division protein ZapB Pkinase PF00069.25 EPS30444.1 - 4.4e-26 91.8 0.0 5.9e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS30444.1 - 6.2e-14 51.9 0.0 8.6e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EPS30444.1 - 4.5e-09 35.6 0.0 6.4e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EPS30444.1 - 0.00013 21.9 0.2 0.0015 18.5 0.0 2.4 2 1 0 3 3 3 1 Phosphotransferase enzyme family Kelch_3 PF13415.6 EPS30445.1 - 9.7e-34 115.0 7.6 5.6e-07 29.7 0.1 6.0 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_4 PF13418.6 EPS30445.1 - 4.6e-33 113.0 9.8 3.6e-08 33.3 0.9 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 EPS30445.1 - 1.3e-30 104.8 3.3 2.3e-07 30.6 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.25 EPS30445.1 - 1.5e-28 98.1 0.2 1.2e-10 40.8 0.1 6.0 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 EPS30445.1 - 6e-28 96.2 4.8 1.3e-10 41.1 0.1 6.4 4 1 2 6 6 6 5 Kelch motif Kelch_2 PF07646.15 EPS30445.1 - 7.9e-23 79.5 3.6 5.1e-10 38.9 0.2 6.6 6 0 0 6 6 6 4 Kelch motif TPR_MLP1_2 PF07926.12 EPS30445.1 - 0.007 16.4 14.5 0.007 16.4 14.5 7.5 6 2 2 8 8 8 2 TPR/MLP1/MLP2-like protein RAG2 PF03089.14 EPS30445.1 - 0.11 11.4 0.0 2.3 7.1 0.0 2.9 3 1 0 3 3 3 0 Recombination activating protein 2 Papilin_u7 PF16626.5 EPS30446.1 - 0.17 12.5 4.6 0.3 11.7 4.6 1.4 1 0 0 1 1 1 0 Linking region between Kunitz_BPTI and I-set on papilin Raptor_N PF14538.6 EPS30447.1 - 2.3e-63 212.6 0.0 4.9e-63 211.5 0.0 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 EPS30447.1 - 1.2e-05 25.9 7.2 0.51 11.3 0.1 6.3 5 1 0 5 5 5 2 WD domain, G-beta repeat BBS2_Mid PF14783.6 EPS30447.1 - 0.012 15.7 0.5 2.6 8.1 0.1 3.0 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region HEAT PF02985.22 EPS30447.1 - 0.03 14.6 0.8 19 5.8 0.1 3.6 3 0 0 3 3 3 0 HEAT repeat DUF908 PF06012.12 EPS30447.1 - 0.36 10.2 0.0 0.36 10.2 0.0 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) zf-RING_2 PF13639.6 EPS30449.1 - 5e-13 49.2 5.4 7.8e-13 48.5 5.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EPS30449.1 - 2.3e-09 36.8 2.2 2.3e-09 36.8 2.2 1.7 2 0 0 2 2 2 1 RING-like zinc finger PA PF02225.22 EPS30449.1 - 2.6e-09 37.0 0.0 6.7e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.6 EPS30449.1 - 5.2e-09 35.8 4.4 8.5e-09 35.1 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EPS30449.1 - 1.3e-08 35.0 2.8 2.4e-08 34.1 2.8 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EPS30449.1 - 1.4e-08 34.4 3.6 2.3e-08 33.8 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EPS30449.1 - 2e-07 30.9 2.9 3.1e-07 30.3 2.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EPS30449.1 - 4.9e-06 26.3 3.1 7.4e-06 25.7 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPS30449.1 - 6.5e-06 26.1 1.9 1.3e-05 25.2 0.4 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EPS30449.1 - 0.00053 20.0 0.3 0.001 19.1 0.3 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EPS30449.1 - 0.0027 17.5 2.9 0.0046 16.8 2.9 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EPS30449.1 - 0.043 14.0 2.7 0.11 12.7 2.7 1.7 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 EPS30449.1 - 0.059 13.0 2.9 0.11 12.2 2.9 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 EPS30449.1 - 0.068 13.4 2.7 0.16 12.1 2.7 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.7 EPS30449.1 - 0.37 10.9 4.1 0.7 10.1 4.1 1.5 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.29 EPS30449.1 - 0.48 10.3 2.8 0.86 9.5 2.8 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.6 EPS30449.1 - 0.59 10.0 3.1 1.1 9.1 3.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 EPS30449.1 - 1.7 9.0 3.6 3.1 8.2 3.6 1.4 1 0 0 1 1 1 0 RING-like domain FHA PF00498.26 EPS30450.1 - 4.9e-16 58.8 0.1 1.1e-15 57.7 0.1 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EPS30450.1 - 0.00037 20.8 0.0 0.00098 19.4 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain YhfZ_C PF14503.6 EPS30450.1 - 0.0026 17.3 0.0 0.0049 16.4 0.0 1.3 1 0 0 1 1 1 1 YhfZ C-terminal domain EzrA PF06160.12 EPS30450.1 - 0.095 10.9 20.4 0.0085 14.3 15.2 1.6 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DUF812 PF05667.11 EPS30450.1 - 2.4 7.0 26.3 1.3 7.9 2.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF812) YabA PF06156.13 EPS30450.1 - 2.9 8.6 20.1 0.048 14.3 5.9 3.3 3 0 0 3 3 3 0 Initiation control protein YabA Romo1 PF10247.9 EPS30451.1 - 1.6e-28 98.9 16.1 2e-28 98.6 16.1 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 EPS30451.1 - 0.0084 16.5 5.1 0.011 16.1 5.1 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family MAP65_ASE1 PF03999.12 EPS30453.1 - 1.2 7.8 5.0 1.3 7.6 5.0 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) LRR_8 PF13855.6 EPS30454.1 - 1.1e-10 41.0 9.1 1.8e-10 40.4 4.7 2.9 3 0 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 EPS30454.1 - 1.8e-09 37.7 12.1 2.6e-06 27.7 1.8 4.2 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EPS30454.1 - 0.00034 20.1 0.5 0.00056 19.5 0.5 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_1 PF00560.33 EPS30454.1 - 0.14 12.8 7.9 26 5.9 0.1 4.9 5 0 0 5 5 5 0 Leucine Rich Repeat Rpp20 PF12328.8 EPS30455.1 - 2.7e-50 169.9 10.3 4.2e-50 169.3 10.3 1.3 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 EPS30455.1 - 6.2e-19 67.6 0.6 1.3e-18 66.6 0.6 1.6 1 0 0 1 1 1 1 Alba RR_TM4-6 PF06459.12 EPS30455.1 - 9.4 6.0 10.3 13 5.5 10.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3583 PF12126.8 EPS30458.1 - 1.1 8.7 7.1 0.28 10.6 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3583) Glyco_transf_24 PF18404.1 EPS30459.1 - 8.2e-147 487.7 0.4 1.3e-146 487.1 0.4 1.3 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 EPS30459.1 - 4e-65 220.3 0.0 1.9e-63 214.8 0.0 2.7 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 EPS30459.1 - 7.7e-50 169.4 0.8 1.6e-49 168.4 0.1 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_15 PF18403.1 EPS30459.1 - 1.3e-48 165.8 0.0 7.6e-47 160.0 0.1 2.3 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 EPS30459.1 - 1.7e-48 163.9 2.2 1.2e-46 158.0 0.2 3.1 3 0 0 3 3 3 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 EPS30459.1 - 5.4e-43 145.5 0.0 1.1e-42 144.5 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.20 EPS30459.1 - 0.0028 17.2 0.0 0.0049 16.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Myb_DNA-binding PF00249.31 EPS30460.1 - 2.8e-15 56.2 5.8 8.4e-09 35.5 0.0 3.5 3 1 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EPS30460.1 - 3.1e-13 49.8 7.1 3.5e-09 36.8 0.1 3.4 4 0 0 4 4 4 2 Myb-like DNA-binding domain KH_6 PF15985.5 EPS30461.1 - 3.8e-17 62.4 0.1 7.7e-17 61.4 0.1 1.5 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 EPS30461.1 - 5.2e-11 42.3 0.5 1.4e-10 40.9 0.5 1.8 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain HSP70 PF00012.20 EPS30462.1 - 6.1e-86 288.9 0.8 6.1e-86 288.9 0.8 1.3 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EPS30462.1 - 1e-10 41.0 0.2 1.5e-10 40.4 0.2 1.3 1 0 0 1 1 1 1 MreB/Mbl protein Peripla_BP_6 PF13458.6 EPS30462.1 - 0.0049 16.6 1.1 0.05 13.3 0.4 2.3 2 0 0 2 2 2 1 Periplasmic binding protein SUR7 PF06687.12 EPS30463.1 - 8.3e-43 146.5 7.1 9.6e-43 146.3 7.1 1.0 1 0 0 1 1 1 1 SUR7/PalI family Amastin PF07344.11 EPS30463.1 - 0.032 14.1 8.7 0.022 14.6 6.9 1.6 2 0 0 2 2 2 0 Amastin surface glycoprotein Clc-like PF07062.12 EPS30463.1 - 0.037 13.5 3.1 0.061 12.8 3.1 1.4 1 0 0 1 1 1 0 Clc-like DUF4491 PF14898.6 EPS30463.1 - 0.31 11.5 3.3 1.1 9.7 0.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4491) Fig1 PF12351.8 EPS30463.1 - 0.53 10.2 9.7 1.3 9.0 9.7 1.6 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 Rogdi_lz PF10259.9 EPS30464.1 - 6.9e-82 274.9 0.0 7.9e-82 274.7 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein DUF4715 PF15835.5 EPS30464.1 - 0.024 14.7 0.0 0.044 13.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4715) Rsm22 PF09243.10 EPS30465.1 - 3.4e-33 115.1 0.0 1.3e-30 106.7 0.0 2.9 2 1 0 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 DASH_Spc19 PF08287.11 EPS30466.1 - 1.5e-51 174.4 8.2 1.9e-51 174.0 8.2 1.2 1 0 0 1 1 1 1 Spc19 Mur_ligase_M PF08245.12 EPS30466.1 - 0.027 14.5 0.0 0.029 14.4 0.0 1.3 1 1 0 1 1 1 0 Mur ligase middle domain Glyco_hydro_63 PF03200.16 EPS30466.1 - 0.099 11.4 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 63 C-terminal domain COG5 PF10392.9 EPS30466.1 - 1.4 9.1 9.1 1.9 8.7 0.4 3.0 2 1 1 3 3 3 0 Golgi transport complex subunit 5 ATP-synt_J PF04911.12 EPS30467.1 - 9.7e-25 85.9 0.1 1e-24 85.8 0.1 1.0 1 0 0 1 1 1 1 ATP synthase j chain HNH_2 PF13391.6 EPS30468.1 - 7.1e-05 22.9 0.0 0.00013 22.1 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease EF-hand_1 PF00036.32 EPS30469.1 - 6.2e-12 44.2 5.4 5.5e-05 22.4 0.2 3.4 3 0 0 3 3 3 2 EF hand ZZ PF00569.17 EPS30469.1 - 2.7e-11 43.1 4.1 2.7e-11 43.1 4.1 1.6 2 0 0 2 2 2 1 Zinc finger, ZZ type EF-hand_6 PF13405.6 EPS30469.1 - 1.5e-09 37.0 2.7 0.00015 21.5 0.1 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EPS30469.1 - 2.7e-09 37.4 2.3 5.9e-09 36.3 1.3 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 EPS30469.1 - 8.9e-05 22.3 5.8 0.063 13.1 0.1 3.1 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 EPS30469.1 - 0.00045 19.6 5.2 0.12 11.9 0.2 3.0 3 0 0 3 3 3 2 EF hand C1_2 PF03107.16 EPS30469.1 - 0.009 16.3 3.8 0.016 15.5 3.8 1.3 1 0 0 1 1 1 1 C1 domain DUF4685 PF15737.5 EPS30469.1 - 0.22 12.0 4.7 0.15 12.5 1.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4685) MFS_1 PF07690.16 EPS30470.1 - 1.5e-44 152.4 55.1 1.5e-44 152.4 55.1 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS30470.1 - 3.1e-16 59.3 6.9 3.1e-16 59.3 6.9 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter Meth_synt_2 PF01717.18 EPS30471.1 - 4e-09 36.2 0.0 5.6e-07 29.1 0.0 2.3 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EPS30471.1 - 0.02 14.4 0.0 0.085 12.3 0.0 1.9 2 0 0 2 2 2 0 Cobalamin-independent synthase, N-terminal domain Peptidase_M24 PF00557.24 EPS30472.1 - 1.3e-47 162.2 0.1 1.7e-47 161.8 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 EPS30472.1 - 4.1e-19 68.6 7.9 4.1e-19 68.6 7.9 2.1 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 EPS30472.1 - 0.00052 20.0 4.4 0.00052 20.0 4.4 2.3 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.16 EPS30472.1 - 0.25 11.3 3.3 0.52 10.2 3.3 1.6 1 0 0 1 1 1 0 HIT zinc finger FAD_binding_3 PF01494.19 EPS30473.1 - 5.5e-14 52.2 0.0 1.8e-13 50.5 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EPS30473.1 - 6.3e-05 22.3 0.0 0.0001 21.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPS30473.1 - 0.00035 21.1 0.0 0.0055 17.2 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EPS30473.1 - 0.0016 17.2 0.1 0.0024 16.7 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 EPS30473.1 - 0.002 17.8 0.4 0.0055 16.3 0.2 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EPS30473.1 - 0.0037 17.5 0.9 0.016 15.4 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 EPS30473.1 - 0.0095 15.2 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EPS30473.1 - 0.0099 15.0 0.1 0.024 13.7 0.1 1.6 1 1 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 EPS30473.1 - 0.012 15.0 5.3 0.05 12.9 1.8 2.7 2 1 0 2 2 2 0 FAD dependent oxidoreductase WD40 PF00400.32 EPS30474.1 - 4.8e-32 109.5 8.0 7.9e-08 32.9 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS30474.1 - 4.4e-13 49.4 0.0 0.0021 18.3 0.0 4.9 3 2 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EPS30474.1 - 0.0039 16.8 0.0 0.013 15.1 0.0 2.0 1 1 0 1 1 1 1 PQQ-like domain Cornichon PF03311.14 EPS30475.1 - 2.1e-49 166.9 13.8 2.4e-49 166.7 13.8 1.0 1 0 0 1 1 1 1 Cornichon protein ABC2_membrane PF01061.24 EPS30476.1 - 2.9e-37 128.2 21.9 2.9e-37 128.2 21.9 1.8 2 0 0 2 2 1 1 ABC-2 type transporter ABC_tran PF00005.27 EPS30476.1 - 5.2e-24 85.3 0.4 1.1e-23 84.2 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EPS30476.1 - 5.7e-05 23.1 0.0 0.42 10.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EPS30476.1 - 0.0054 17.1 0.0 0.011 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EPS30476.1 - 0.012 15.8 0.0 0.029 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EPS30476.1 - 0.014 15.1 0.4 0.034 13.9 0.4 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 EPS30476.1 - 0.037 14.6 0.0 0.084 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EPS30476.1 - 0.043 13.7 0.0 0.069 13.1 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 EPS30476.1 - 0.047 13.6 0.2 0.092 12.6 0.2 1.4 1 0 0 1 1 1 0 RsgA GTPase SMC_N PF02463.19 EPS30476.1 - 0.1 12.0 0.0 2.3 7.6 0.0 2.4 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EPS30476.1 - 0.14 12.6 2.4 0.16 12.5 0.4 1.9 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EPS30476.1 - 0.14 12.2 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EPS30476.1 - 0.18 11.9 0.0 0.39 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC2_membrane_3 PF12698.7 EPS30476.1 - 0.29 10.2 30.8 1 8.4 30.9 1.9 1 1 0 1 1 1 0 ABC-2 family transporter protein AAA_25 PF13481.6 EPS30476.1 - 0.54 9.8 2.3 0.62 9.6 0.1 2.1 3 0 0 3 3 3 0 AAA domain Aminotran_1_2 PF00155.21 EPS30477.1 - 5.2e-41 141.0 0.0 6.5e-41 140.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EPS30477.1 - 5.1e-07 29.0 0.0 7.9e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EPS30477.1 - 5.7e-07 28.4 0.0 7.9e-07 27.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_MocR PF12897.7 EPS30477.1 - 5.2e-06 25.5 0.0 7.1e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Beta_elim_lyase PF01212.21 EPS30477.1 - 1.6e-05 24.3 0.0 2.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EPS30477.1 - 0.0034 16.7 0.0 0.0051 16.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family AMP-binding PF00501.28 EPS30478.1 - 9.3e-62 209.0 0.0 1.2e-61 208.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EPS30478.1 - 2.5e-07 31.6 0.0 6.8e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fungal_trans PF04082.18 EPS30479.1 - 3.8e-14 52.4 0.5 7.7e-14 51.4 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS30479.1 - 0.0034 17.5 2.6 0.0069 16.5 2.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Polyketide_cyc PF03364.20 EPS30480.1 - 1.5e-22 80.2 0.0 7e-22 78.0 0.0 1.8 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 EPS30480.1 - 0.00036 20.8 0.1 0.43 10.8 0.0 2.2 2 0 0 2 2 2 2 Polyketide cyclase / dehydrase and lipid transport Sod_Fe_C PF02777.18 EPS30481.1 - 3.5e-18 65.6 0.1 2.1e-10 40.7 0.2 2.4 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EPS30481.1 - 0.049 14.1 0.1 0.08 13.4 0.1 1.4 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain Granulin PF00396.18 EPS30482.1 - 2.1 8.8 26.7 2 8.8 4.8 3.5 2 1 1 3 3 3 0 Granulin PIG-S PF10510.9 EPS30483.1 - 5e-184 612.9 0.0 5.7e-184 612.7 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein FmiP_Thoc5 PF09766.9 EPS30484.1 - 1.8e-31 109.8 13.1 2.1e-31 109.6 13.1 1.1 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 SPATA1_C PF15743.5 EPS30484.1 - 0.0051 16.9 2.6 0.0051 16.9 2.6 2.1 2 0 0 2 2 2 1 Spermatogenesis-associated C-terminus Casc1_N PF15927.5 EPS30484.1 - 0.022 14.4 7.4 0.022 14.4 7.4 1.7 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus DUF4200 PF13863.6 EPS30484.1 - 0.047 14.1 13.9 0.27 11.7 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF1664 PF07889.12 EPS30484.1 - 0.16 12.0 3.9 1.3 9.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) YabA PF06156.13 EPS30484.1 - 0.4 11.3 7.8 6.7 7.4 0.2 2.2 2 0 0 2 2 2 0 Initiation control protein YabA ATG16 PF08614.11 EPS30484.1 - 0.43 10.8 14.5 2.5 8.3 2.0 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Mod_r PF07200.13 EPS30484.1 - 0.49 10.5 16.4 1.2 9.2 6.6 2.8 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein APG6_N PF17675.1 EPS30484.1 - 0.69 10.4 15.7 4 8.0 0.7 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF3450 PF11932.8 EPS30484.1 - 0.79 9.0 10.8 1.2 8.4 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF349 PF03993.12 EPS30484.1 - 4.1 7.8 12.3 0.48 10.8 7.0 2.1 2 1 0 2 2 2 0 Domain of Unknown Function (DUF349) HlyIII PF03006.20 EPS30485.1 - 4.4e-62 209.7 23.3 5.5e-62 209.4 23.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related 7TMR-HDED PF07697.11 EPS30485.1 - 0.016 15.3 0.5 0.024 14.8 0.5 1.1 1 0 0 1 1 1 0 7TM-HD extracellular SPC12 PF06645.13 EPS30485.1 - 0.025 14.6 0.3 0.025 14.6 0.3 2.3 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Asr PF06392.11 EPS30485.1 - 0.06 13.7 1.0 0.13 12.7 1.0 1.5 1 0 0 1 1 1 0 Acid shock protein repeat SKA2 PF16740.5 EPS30485.1 - 0.33 10.8 1.8 13 5.6 0.0 2.3 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Methyltransf_25 PF13649.6 EPS30486.1 - 6.5e-15 55.6 0.0 2.2e-14 53.9 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPS30486.1 - 1.6e-13 51.2 0.0 4.8e-13 49.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS30486.1 - 2e-12 47.6 0.0 6.1e-12 46.0 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPS30486.1 - 5.3e-12 45.9 0.0 1e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPS30486.1 - 5.8e-08 32.7 0.0 9.7e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPS30486.1 - 1.9e-07 30.7 0.0 2.7e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 EPS30486.1 - 0.00022 22.2 0.0 0.0006 20.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EPS30486.1 - 0.0044 16.2 0.0 0.26 10.5 0.0 2.2 1 1 1 2 2 2 1 NNMT/PNMT/TEMT family MTS PF05175.14 EPS30486.1 - 0.0089 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.15 EPS30486.1 - 0.02 14.7 0.0 0.44 10.4 0.0 2.2 1 1 0 1 1 1 0 Hypothetical methyltransferase DUF3419 PF11899.8 EPS30486.1 - 0.033 13.4 0.0 0.054 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) Methyltransf_32 PF13679.6 EPS30486.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CS PF04969.16 EPS30488.1 - 3.4e-18 66.4 0.3 7.2e-18 65.4 0.0 1.7 2 0 0 2 2 2 1 CS domain Diphthamide_syn PF01866.17 EPS30492.1 - 6e-86 288.6 0.0 1.2e-85 287.6 0.0 1.5 1 1 0 1 1 1 1 Putative diphthamide synthesis protein ANAPC4_WD40 PF12894.7 EPS30493.1 - 9.9e-06 25.8 0.0 0.011 16.0 0.0 3.1 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EPS30493.1 - 0.048 14.5 8.5 1.6 9.7 0.0 4.8 5 1 0 5 5 5 0 WD domain, G-beta repeat RAB3GAP2_N PF14655.6 EPS30493.1 - 0.082 12.2 0.0 4.1 6.5 0.0 2.7 3 1 1 4 4 4 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF3245 PF11595.8 EPS30493.1 - 2.3 8.7 9.3 0.75 10.3 3.4 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3245) Glyco_hydro_7 PF00840.20 EPS30494.1 - 3.9e-208 691.5 17.8 4.4e-208 691.3 17.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Abhydrolase_1 PF00561.20 EPS30495.1 - 8.4e-11 42.0 0.6 4.1e-10 39.7 0.2 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPS30495.1 - 9.3e-11 42.8 1.0 1.6e-10 41.9 1.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPS30495.1 - 6.7e-10 38.6 0.0 2.1e-09 37.0 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 DLH PF01738.18 EPS30495.1 - 0.0002 21.0 0.5 0.75 9.3 0.0 3.2 3 0 0 3 3 3 3 Dienelactone hydrolase family Pax2_C PF12403.8 EPS30496.1 - 0.044 13.9 2.2 0.048 13.7 2.2 1.1 1 0 0 1 1 1 0 Paired-box protein 2 C terminal Aldedh PF00171.22 EPS30496.1 - 0.09 11.3 0.0 0.099 11.1 0.0 1.0 1 0 0 1 1 1 0 Aldehyde dehydrogenase family Abhydrolase_3 PF07859.13 EPS30497.1 - 9.2e-38 130.2 0.0 1.1e-37 129.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EPS30497.1 - 6.4e-06 25.3 0.0 9e-05 21.5 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 EPS30497.1 - 0.00025 20.6 0.0 0.012 15.1 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 EPS30497.1 - 0.0025 16.8 0.0 0.004 16.1 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 EPS30497.1 - 0.0034 16.4 0.0 0.0066 15.5 0.0 1.5 1 1 0 1 1 1 1 Chlorophyllase DLH PF01738.18 EPS30497.1 - 0.0096 15.5 0.0 0.083 12.4 0.0 2.0 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 EPS30497.1 - 0.012 15.4 0.0 0.028 14.2 0.0 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase AXE1 PF05448.12 EPS30497.1 - 0.039 12.6 0.0 0.12 11.0 0.0 1.6 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DUF2974 PF11187.8 EPS30497.1 - 0.046 13.3 0.0 0.071 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) BAAT_C PF08840.11 EPS30497.1 - 0.054 13.4 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.20 EPS30497.1 - 0.059 13.0 0.0 0.09 12.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPS30497.1 - 0.071 13.7 0.0 0.091 13.3 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Esterase_phd PF10503.9 EPS30497.1 - 0.098 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase Cutinase PF01083.22 EPS30497.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Cutinase APG5 PF04106.12 EPS30498.1 - 4.7e-65 219.4 0.0 6.3e-65 219.0 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Apg5 Spike_torovirin PF17072.5 EPS30498.1 - 0.035 11.3 0.0 0.046 10.9 0.0 1.0 1 0 0 1 1 1 0 Torovirinae spike glycoprotein Ank_4 PF13637.6 EPS30499.1 - 3.6e-50 167.7 19.0 1e-09 38.7 0.1 11.2 2 2 8 11 11 11 10 Ankyrin repeats (many copies) Ank_2 PF12796.7 EPS30499.1 - 1.7e-47 159.9 15.0 3.2e-14 53.3 0.5 6.6 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EPS30499.1 - 5.4e-41 133.9 14.8 6.5e-05 23.0 0.2 12.9 12 0 0 12 12 12 8 Ankyrin repeat Ank PF00023.30 EPS30499.1 - 2.1e-37 125.9 28.7 2.4e-06 27.7 0.2 12.1 12 0 0 12 12 12 9 Ankyrin repeat Ank_5 PF13857.6 EPS30499.1 - 3.2e-34 116.6 11.8 9.7e-07 29.0 0.0 8.4 6 2 3 9 9 9 6 Ankyrin repeats (many copies) AAA_22 PF13401.6 EPS30499.1 - 1.7e-11 44.6 0.0 5.8e-11 42.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EPS30499.1 - 8e-08 32.4 0.2 3.8e-07 30.2 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 EPS30499.1 - 6.1e-06 26.7 0.3 3.9e-05 24.1 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 EPS30499.1 - 0.00012 21.4 0.0 0.00022 20.5 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain ATPase_2 PF01637.18 EPS30499.1 - 0.001 19.0 0.0 0.0022 17.9 0.0 1.5 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA PF00004.29 EPS30499.1 - 0.0011 19.4 0.0 0.0036 17.7 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EPS30499.1 - 0.0026 17.8 0.2 0.48 10.5 0.0 3.0 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.6 EPS30499.1 - 0.021 15.0 0.4 0.16 12.1 0.0 2.6 3 0 0 3 3 3 0 AAA domain IcmF_C PF06744.12 EPS30499.1 - 0.2 11.3 0.3 0.79 9.3 0.0 2.0 2 0 0 2 2 2 0 Type VI secretion protein IcmF C-terminal SAM_2 PF07647.17 EPS30500.1 - 2.3e-13 50.0 0.1 5.8e-13 48.7 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EPS30500.1 - 5.7e-12 45.9 0.1 1.2e-11 44.9 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.29 EPS30500.1 - 9.1e-07 29.3 0.1 2.7e-06 27.9 0.1 1.9 1 1 0 1 1 1 1 PH domain SAM_Ste50p PF09235.10 EPS30500.1 - 0.00032 20.9 0.0 0.00062 20.0 0.0 1.5 1 0 0 1 1 1 1 Ste50p, sterile alpha motif SAM_3 PF18016.1 EPS30500.1 - 0.00062 19.5 0.0 0.0056 16.5 0.0 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SLX9 PF15341.6 EPS30500.1 - 0.031 14.7 1.3 0.7 10.3 0.4 2.4 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 PH_9 PF15410.6 EPS30500.1 - 0.11 12.9 0.4 0.3 11.5 0.2 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain Fungal_trans_2 PF11951.8 EPS30502.1 - 3.1e-90 302.8 0.6 3.8e-90 302.5 0.6 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS30502.1 - 4e-07 30.0 8.3 7.7e-07 29.1 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF569 PF04601.13 EPS30504.1 - 0.055 13.2 0.0 0.09 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF569) SHR3_chaperone PF08229.11 EPS30505.1 - 2.4e-79 264.7 0.0 2.7e-79 264.5 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 TcpE PF12648.7 EPS30505.1 - 9.2 6.9 6.7 3.5 8.2 2.9 2.1 2 1 0 2 2 2 0 TcpE family Arrestin_N PF00339.29 EPS30506.1 - 7.5e-14 52.0 0.0 7.7e-13 48.7 0.0 2.4 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EPS30506.1 - 1.2e-09 38.7 0.0 6.9e-07 29.8 0.0 2.6 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Mnd1 PF03962.15 EPS30507.1 - 2.7e-23 82.0 0.0 1.4e-22 79.8 0.0 2.0 2 0 0 2 2 2 1 Mnd1 HTH domain LZ3wCH PF18517.1 EPS30507.1 - 0.0021 18.1 0.0 0.0044 17.1 0.0 1.5 1 0 0 1 1 1 1 Leucine zipper with capping helix domain DUF4094 PF13334.6 EPS30507.1 - 0.11 12.9 0.2 0.29 11.6 0.0 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) UAF_Rrn10 PF05234.11 EPS30508.1 - 0.0005 20.3 0.0 0.0011 19.2 0.0 1.6 1 1 0 1 1 1 1 UAF complex subunit Rrn10 MRI PF15325.6 EPS30508.1 - 0.042 14.9 0.9 0.089 13.9 0.5 1.8 1 1 0 1 1 1 0 Modulator of retrovirus infection DUF1195 PF06708.11 EPS30508.1 - 0.043 13.6 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1195) WD40 PF00400.32 EPS30509.1 - 3.6e-19 68.7 20.1 2.5e-05 25.0 0.6 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS30509.1 - 8.5e-09 35.6 0.1 0.04 14.2 0.0 4.4 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain MacB_PCD PF12704.7 EPS30512.1 - 0.16 12.3 2.0 0.47 10.8 2.1 1.6 2 0 0 2 2 2 0 MacB-like periplasmic core domain MFS_1 PF07690.16 EPS30513.1 - 7.8e-32 110.6 44.3 7.8e-32 110.6 44.3 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EPS30513.1 - 2.1e-17 62.8 25.3 2.7e-17 62.5 25.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EPS30513.1 - 3e-11 42.9 11.0 3e-11 42.9 11.0 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.13 EPS30513.1 - 0.0014 17.1 5.0 0.0014 17.1 5.0 2.2 2 0 0 2 2 2 1 Transmembrane secretion effector Zip PF02535.22 EPS30514.1 - 1.5e-38 132.9 14.5 1.5e-38 132.9 14.5 2.4 2 1 0 2 2 2 2 ZIP Zinc transporter BSP_II PF05432.11 EPS30514.1 - 0.0037 17.0 5.4 0.0062 16.3 5.4 1.3 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) CDC45 PF02724.14 EPS30514.1 - 2.3 6.4 4.0 2.3 6.4 3.0 1.4 2 0 0 2 2 2 0 CDC45-like protein VIT PF08487.10 EPS30515.1 - 5.4e-28 97.4 0.0 1.2e-27 96.3 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 EPS30515.1 - 3.1e-26 92.2 0.0 5.9e-26 91.3 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EPS30515.1 - 2.1e-12 47.7 0.0 5.6e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 EPS30515.1 - 5.9e-11 42.9 0.0 1.1e-10 42.1 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 EPS30515.1 - 1e-06 28.5 0.0 2.7e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.14 EPS30515.1 - 0.0024 17.3 0.0 0.004 16.6 0.0 1.2 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein NIR_SIR_ferr PF03460.17 EPS30516.1 - 0.096 12.6 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Nitrite/Sulfite reductase ferredoxin-like half domain Pox_A28 PF04584.14 EPS30516.1 - 0.13 12.4 0.0 0.19 11.9 0.0 1.3 1 1 0 1 1 1 0 Poxvirus A28 family Pyr_redox_3 PF13738.6 EPS30518.1 - 1.6e-19 70.3 0.0 1.7e-16 60.4 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EPS30518.1 - 1e-15 57.7 0.0 4.3e-13 49.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EPS30518.1 - 4.4e-12 45.2 0.2 4.6e-09 35.2 0.1 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.6 EPS30518.1 - 6.7e-09 35.3 0.1 8.6e-07 28.4 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EPS30518.1 - 2.7e-06 27.5 0.0 1e-05 25.7 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EPS30518.1 - 3.5e-05 23.2 0.0 0.00015 21.2 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 EPS30518.1 - 0.0002 21.9 0.4 1.9 9.1 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EPS30518.1 - 0.00023 20.5 0.0 0.29 10.3 0.0 2.4 2 0 0 2 2 2 2 Thi4 family FAD_binding_2 PF00890.24 EPS30518.1 - 0.0005 19.3 0.5 0.0012 18.0 0.4 1.7 2 0 0 2 2 2 1 FAD binding domain 2-Hacid_dh_C PF02826.19 EPS30518.1 - 0.0018 17.6 0.1 0.14 11.5 0.1 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 EPS30518.1 - 0.0045 15.7 0.2 0.014 14.1 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.22 EPS30518.1 - 0.0055 15.8 0.8 0.35 9.9 0.1 2.6 3 0 0 3 3 3 1 Glucose inhibited division protein A IlvN PF07991.12 EPS30518.1 - 0.018 14.6 0.1 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain SnoaL_2 PF12680.7 EPS30518.1 - 0.02 15.6 0.2 0.43 11.3 0.0 3.1 3 0 0 3 3 3 0 SnoaL-like domain AlaDh_PNT_C PF01262.21 EPS30518.1 - 0.025 13.9 0.1 0.074 12.3 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 EPS30518.1 - 0.054 13.4 0.1 0.9 9.4 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 EPS30518.1 - 0.18 11.1 1.0 0.67 9.2 1.0 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase Sugar_tr PF00083.24 EPS30521.1 - 3.2e-34 118.6 21.0 2.7e-24 85.8 6.2 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EPS30521.1 - 8e-26 90.8 26.4 8e-26 90.8 26.4 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF4231 PF14015.6 EPS30521.1 - 6.6 7.3 9.6 3.2 8.3 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF4231) MOSC PF03473.17 EPS30524.1 - 6.8e-32 110.2 0.0 1.3e-31 109.3 0.0 1.5 1 0 0 1 1 1 1 MOSC domain Aminotran_5 PF00266.19 EPS30524.1 - 3.2e-31 108.6 0.0 4.8e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.16 EPS30524.1 - 1.5e-28 99.1 0.0 3e-28 98.1 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Mitoc_mL59 PF18126.1 EPS30525.1 - 5.2e-48 162.6 2.4 7.2e-48 162.1 2.4 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein mL59 Suf PF05843.14 EPS30526.1 - 1.5e-07 31.8 6.2 0.00069 19.7 0.4 3.4 2 2 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 EPS30526.1 - 1.1e-05 25.8 12.7 0.27 12.1 0.0 8.0 6 2 4 10 10 10 2 Tetratricopeptide repeat TPR_19 PF14559.6 EPS30526.1 - 0.00038 20.9 0.1 4.3 7.9 0.0 4.1 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EPS30526.1 - 0.017 15.4 1.6 1.3 9.4 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat FAT PF02259.23 EPS30526.1 - 0.018 14.3 1.5 0.11 11.7 0.4 2.6 1 1 2 3 3 3 0 FAT domain DUF4810 PF16068.5 EPS30526.1 - 0.15 12.6 0.7 5.4 7.6 0.0 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF4810) HAT PF02184.16 EPS30526.1 - 0.2 11.6 16.1 13 5.8 0.1 6.1 6 0 0 6 6 6 0 HAT (Half-A-TPR) repeat DEAD PF00270.29 EPS30527.1 - 4.2e-47 160.2 0.0 3.8e-46 157.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPS30527.1 - 1e-29 103.1 0.1 8.3e-29 100.2 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF2986 PF11661.8 EPS30527.1 - 0.0023 18.4 4.9 0.01 16.3 4.9 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2986) ResIII PF04851.15 EPS30527.1 - 0.0028 17.7 0.0 0.0065 16.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3334 PF11813.8 EPS30527.1 - 0.055 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) ERAP1_C PF11838.8 EPS30528.1 - 8.7e-91 304.7 0.0 9.3e-90 301.4 0.0 2.2 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 EPS30528.1 - 2.7e-84 282.1 0.4 4.1e-84 281.5 0.4 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EPS30528.1 - 1.8e-57 194.6 1.6 2.5e-57 194.1 0.7 1.7 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain DUF2808 PF10989.8 EPS30528.1 - 0.00018 21.5 0.1 0.00042 20.3 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2808) AA_permease_2 PF13520.6 EPS30529.1 - 1e-90 304.6 33.0 1.3e-90 304.3 33.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPS30529.1 - 3.6e-18 65.4 30.4 5.3e-18 64.9 30.4 1.2 1 0 0 1 1 1 1 Amino acid permease DUF3543 PF12063.8 EPS30530.1 - 1.1e-95 319.8 0.0 1.9e-95 319.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 EPS30530.1 - 3.8e-62 210.0 0.0 7.3e-62 209.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS30530.1 - 6.8e-42 143.5 0.0 1.2e-41 142.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase T2SSF PF00482.23 EPS30532.1 - 0.026 14.5 0.1 0.062 13.3 0.1 1.7 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F DHHC PF01529.20 EPS30532.1 - 0.099 12.7 0.5 0.31 11.1 0.5 1.8 1 0 0 1 1 1 0 DHHC palmitoyltransferase Diphthami_syn_2 PF01902.17 EPS30533.1 - 4.3e-19 68.9 0.0 1.9e-11 43.9 0.0 3.9 2 1 0 3 3 3 3 Diphthamide synthase Ribonuc_L-PSP PF01042.21 EPS30533.1 - 2.1e-16 60.0 0.1 1.3e-07 31.7 0.0 3.4 3 0 0 3 3 3 2 Endoribonuclease L-PSP Cwf_Cwc_15 PF04889.12 EPS30533.1 - 0.091 12.5 2.2 0.14 11.9 0.1 2.0 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein zf-C2H2 PF00096.26 EPS30534.1 - 1.7e-12 47.1 11.8 2e-06 28.0 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPS30534.1 - 5.9e-08 32.9 10.0 0.0023 18.6 0.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EPS30534.1 - 3.4e-07 30.4 11.5 7e-07 29.4 4.1 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EPS30534.1 - 1.7e-05 25.0 3.2 0.01 16.1 0.5 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EPS30534.1 - 4.9e-05 23.6 4.5 0.007 16.7 0.3 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EPS30534.1 - 0.00016 21.6 9.2 0.0072 16.3 0.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 EPS30534.1 - 0.0029 17.2 3.1 1.2 8.8 0.1 2.6 1 1 1 2 2 2 2 Zinc-fingers and homeoboxes C2H2 finger domain Lactamase_B_6 PF16661.5 EPS30534.1 - 0.084 12.3 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain zf-LYAR PF08790.11 EPS30534.1 - 0.14 12.1 1.7 16 5.5 0.1 2.6 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-BED PF02892.15 EPS30534.1 - 0.14 12.2 5.4 0.056 13.5 1.6 2.1 1 1 1 2 2 2 0 BED zinc finger zf-C2H2_11 PF16622.5 EPS30534.1 - 0.46 10.3 7.8 9.3 6.1 0.0 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2HE PF16278.5 EPS30534.1 - 0.89 10.0 7.0 5.2 7.6 0.7 2.6 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_2 PF12756.7 EPS30534.1 - 0.97 9.8 3.7 10 6.6 0.4 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) PITH PF06201.13 EPS30540.1 - 4.2e-36 124.4 0.0 6.9e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.20 EPS30540.1 - 1.4e-26 92.4 0.0 2.9e-26 91.4 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EPS30540.1 - 7e-06 26.4 0.0 2e-05 25.0 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 EPS30540.1 - 3.4e-05 23.6 0.0 5.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EPS30540.1 - 0.0003 21.1 0.0 0.064 13.6 0.0 2.4 1 1 1 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 EPS30540.1 - 0.0015 18.0 0.0 0.0066 15.8 0.0 1.8 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 EPS30540.1 - 0.024 14.6 0.1 0.18 11.7 0.1 2.2 1 1 0 1 1 1 0 AhpC/TSA family HyaE PF07449.11 EPS30540.1 - 0.094 12.7 0.0 0.32 11.0 0.0 1.9 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE zf-CSL PF05207.13 EPS30541.1 - 1.1e-20 73.1 3.4 1.8e-20 72.4 3.4 1.4 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 EPS30541.1 - 6.7e-12 45.4 2.2 4.9e-07 29.8 0.6 2.3 2 0 0 2 2 2 2 DnaJ domain peroxidase PF00141.23 EPS30542.1 - 1.3e-50 172.3 0.0 2e-50 171.6 0.0 1.2 1 0 0 1 1 1 1 Peroxidase ArfGap PF01412.18 EPS30545.1 - 3.7e-36 123.8 0.1 8.5e-36 122.6 0.1 1.7 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Glyco_transf_22 PF03901.17 EPS30546.1 - 1.6e-80 271.4 16.3 2.1e-80 271.0 16.3 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Aminotran_3 PF00202.21 EPS30547.1 - 4.8e-118 394.4 0.0 5.5e-118 394.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EPS30547.1 - 0.084 12.0 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II ABC_membrane PF00664.23 EPS30548.1 - 9.7e-54 182.9 39.8 1.6e-33 116.6 19.7 3.2 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.27 EPS30548.1 - 2.7e-47 160.7 0.0 1.4e-25 90.4 0.0 2.9 2 0 0 2 2 2 2 ABC transporter MMR_HSR1 PF01926.23 EPS30548.1 - 8.3e-07 29.1 0.4 0.023 14.8 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.19 EPS30548.1 - 2.8e-06 27.0 0.8 0.23 10.9 0.0 3.7 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 EPS30548.1 - 4.9e-06 26.0 0.0 0.007 15.7 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin RsgA_GTPase PF03193.16 EPS30548.1 - 0.0001 22.3 1.0 0.05 13.5 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 EPS30548.1 - 0.00027 20.9 3.2 0.28 10.9 0.0 3.8 3 1 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EPS30548.1 - 0.0003 20.5 0.8 0.45 10.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EPS30548.1 - 0.00048 20.6 0.9 0.79 10.1 0.1 3.2 2 1 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.23 EPS30548.1 - 0.0011 19.1 0.7 0.29 11.2 0.0 2.7 2 0 0 2 2 2 1 Dynamin family MeaB PF03308.16 EPS30548.1 - 0.0058 15.6 1.8 1.6 7.7 0.0 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_23 PF13476.6 EPS30548.1 - 0.0059 17.1 4.9 0.41 11.1 0.1 3.6 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.6 EPS30548.1 - 0.0073 16.8 0.4 20 5.7 0.0 3.6 3 0 0 3 3 3 0 AAA domain AAA_15 PF13175.6 EPS30548.1 - 0.012 15.4 0.8 1.3 8.7 0.2 2.6 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.17 EPS30548.1 - 0.027 14.6 1.5 0.28 11.3 0.3 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_22 PF13401.6 EPS30548.1 - 0.043 14.1 3.9 7.9 6.8 0.1 3.9 4 0 0 4 4 4 0 AAA domain AAA_28 PF13521.6 EPS30548.1 - 0.26 11.5 1.6 1.6 8.9 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EPS30548.1 - 0.35 10.6 2.5 4.3 7.0 0.1 2.9 3 0 0 3 3 3 0 AAA domain NB-ARC PF00931.22 EPS30548.1 - 0.4 9.8 1.2 6.4 5.9 0.2 2.5 2 0 0 2 2 2 0 NB-ARC domain Coilin_N PF15862.5 EPS30548.1 - 1.4 8.8 4.0 0.4 10.5 0.2 2.0 2 0 0 2 2 2 0 Coilin N-terminus FMN_red PF03358.15 EPS30549.1 - 5e-29 101.0 0.0 7.9e-29 100.4 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EPS30549.1 - 8.2e-09 35.4 0.0 1.3e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Jacalin PF01419.17 EPS30550.1 - 0.004 17.1 0.1 0.0091 15.9 0.1 1.6 1 1 0 1 1 1 1 Jacalin-like lectin domain DUF2244 PF10003.9 EPS30551.1 - 0.16 11.6 0.1 0.16 11.6 0.1 2.4 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) BacA PF02673.18 EPS30551.1 - 0.8 9.4 10.4 0.78 9.4 8.3 1.9 2 0 0 2 2 2 0 Bacitracin resistance protein BacA YbhQ PF11076.8 EPS30551.1 - 3.8 7.5 7.5 5.9 6.9 0.7 2.7 1 1 1 3 3 3 0 Putative inner membrane protein YbhQ RseC_MucC PF04246.12 EPS30551.1 - 9 6.3 6.8 3.1 7.8 3.6 1.8 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC PAP2 PF01569.21 EPS30554.1 - 9e-29 100.0 1.8 2.5e-28 98.5 0.2 2.3 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 EPS30554.1 - 0.031 14.0 3.1 0.13 11.9 3.1 2.0 1 1 0 1 1 1 0 PAP2 superfamily DZR PF12773.7 EPS30555.1 - 0.0027 17.7 45.6 0.52 10.4 6.8 5.2 1 1 3 4 4 4 4 Double zinc ribbon BLM_N PF16202.5 EPS30556.1 - 0.034 13.3 2.2 0.048 12.8 2.2 1.1 1 0 0 1 1 1 0 N-terminal region of Bloom syndrome protein NGP1NT PF08153.12 EPS30557.1 - 5.2e-50 168.9 0.2 8.1e-50 168.3 0.2 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 EPS30557.1 - 1.4e-17 63.8 0.0 2.1e-13 50.3 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EPS30557.1 - 8.1e-06 25.4 0.1 4e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EPS30557.1 - 0.00019 21.6 0.3 0.76 9.8 0.0 3.4 2 1 1 3 3 3 2 Dynamin family Arf PF00025.21 EPS30557.1 - 0.00061 19.3 0.1 0.15 11.5 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EPS30557.1 - 0.0014 18.6 0.0 0.003 17.5 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase Pkinase PF00069.25 EPS30558.1 - 3.4e-42 144.6 0.0 1.1e-41 143.0 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS30558.1 - 1.7e-29 102.9 0.0 2.6e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EPS30558.1 - 8e-05 21.6 0.0 0.00013 20.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EPS30558.1 - 0.0044 16.4 0.0 0.012 15.0 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EPS30558.1 - 0.006 15.9 0.0 0.025 13.9 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EPS30558.1 - 0.029 14.3 0.3 0.51 10.2 0.3 2.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Prefoldin_3 PF13758.6 EPS30559.1 - 1.2e-34 118.4 2.7 2.9e-34 117.1 2.7 1.7 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.7 EPS30559.1 - 3.3e-26 91.9 0.2 3.3e-26 91.9 0.2 5.5 6 2 0 6 6 6 2 Domain of unknown function (DUF3835) RRP36 PF06102.12 EPS30559.1 - 0.39 10.7 6.4 0.23 11.4 1.2 2.5 2 0 0 2 2 2 0 rRNA biogenesis protein RRP36 SlyX PF04102.12 EPS30559.1 - 1.1 9.9 4.4 45 4.8 0.1 3.6 3 0 0 3 3 3 0 SlyX MAT1 PF06391.13 EPS30560.1 - 7.9e-41 140.1 17.5 1e-40 139.8 17.5 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 EPS30560.1 - 3.7e-32 110.0 8.5 5.8e-32 109.4 8.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EPS30560.1 - 5.8e-05 22.9 5.7 0.00013 21.8 5.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPS30560.1 - 0.00011 21.9 3.4 0.00031 20.5 3.5 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EPS30560.1 - 0.00021 21.1 3.8 0.00044 20.0 3.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EPS30560.1 - 0.0021 18.4 6.2 0.0041 17.4 6.2 1.5 1 0 0 1 1 1 1 Ring finger domain Zn_ribbon_17 PF17120.5 EPS30560.1 - 0.0035 16.9 1.5 0.0087 15.7 1.5 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 EPS30560.1 - 0.006 16.4 6.4 0.046 13.5 2.0 2.4 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 EPS30560.1 - 0.012 15.5 7.9 0.12 12.4 8.2 2.2 1 1 1 2 2 2 0 zinc-RING finger domain DUF3797 PF12677.7 EPS30560.1 - 0.078 12.9 2.5 0.19 11.6 2.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3797) CEBP_ZZ PF16366.5 EPS30560.1 - 0.1 12.9 2.6 0.21 11.9 2.6 1.4 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zf-RING_UBOX PF13445.6 EPS30560.1 - 0.16 12.0 6.5 0.34 11.0 6.5 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 EPS30560.1 - 0.23 11.3 8.3 4.5 7.2 8.8 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Cep57_MT_bd PF06657.13 EPS30561.1 - 2.2e-29 101.7 0.9 2.2e-29 101.7 0.9 5.0 7 0 0 7 7 7 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.6 EPS30561.1 - 8.7e-21 73.8 11.4 8.7e-21 73.8 11.4 4.6 6 0 0 6 6 6 2 Centrosome localisation domain of PPC89 HALZ PF02183.18 EPS30561.1 - 0.035 14.3 9.2 0.042 14.1 2.4 3.0 2 0 0 2 2 2 0 Homeobox associated leucine zipper FlaC_arch PF05377.11 EPS30561.1 - 4.7 7.7 12.9 11 6.5 0.2 5.2 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) TSC22 PF01166.18 EPS30561.1 - 4.8 7.6 10.8 3.3 8.1 1.5 4.0 3 0 0 3 3 3 0 TSC-22/dip/bun family Glyco_hydro_64 PF16483.5 EPS30563.1 - 7e-138 459.9 0.6 8.3e-138 459.7 0.6 1.1 1 0 0 1 1 1 1 Beta-1,3-glucanase SWM_repeat PF13753.6 EPS30563.1 - 0.012 15.7 0.1 0.033 14.3 0.1 1.8 1 0 0 1 1 1 0 Putative flagellar system-associated repeat DUF4512 PF14975.6 EPS30563.1 - 0.24 12.2 1.7 0.45 11.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) DUF3682 PF12446.8 EPS30563.1 - 1.6 9.2 10.7 0.045 14.2 3.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) Abhydrolase_6 PF12697.7 EPS30564.1 - 1.6e-13 51.7 1.4 1.9e-13 51.5 1.4 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family ABC_membrane PF00664.23 EPS30565.1 - 1.1e-80 271.2 26.8 7.6e-46 157.0 9.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EPS30565.1 - 6.7e-56 188.6 0.0 1.6e-26 93.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EPS30565.1 - 8.8e-17 61.3 0.7 1.9e-06 27.5 0.0 4.5 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EPS30565.1 - 6.4e-12 45.9 0.5 0.061 13.1 0.0 4.3 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EPS30565.1 - 1.1e-07 31.5 1.2 0.0043 16.8 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EPS30565.1 - 2.5e-06 28.0 0.3 0.23 11.8 0.2 3.6 2 2 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EPS30565.1 - 2.6e-06 27.8 0.5 0.16 12.2 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.6 EPS30565.1 - 4.4e-05 24.1 0.2 0.0099 16.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EPS30565.1 - 0.0001 22.2 0.1 0.33 10.9 0.0 3.1 3 0 0 3 3 3 2 RsgA GTPase AAA_15 PF13175.6 EPS30565.1 - 0.00019 21.3 0.2 0.13 12.0 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.6 EPS30565.1 - 0.00064 19.3 0.0 1.1 8.8 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 EPS30565.1 - 0.00071 20.1 0.0 0.5 10.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.9 EPS30565.1 - 0.0012 17.8 0.1 0.16 10.7 0.1 3.4 3 1 0 3 3 3 1 Predicted ATPase of the ABC class AAA_33 PF13671.6 EPS30565.1 - 0.0041 17.3 0.1 2.3 8.4 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EPS30565.1 - 0.0061 16.6 0.0 5.6 7.0 0.0 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 EPS30565.1 - 0.0062 16.3 0.9 1 9.0 0.1 3.4 3 1 1 4 4 3 1 AAA domain IstB_IS21 PF01695.17 EPS30565.1 - 0.0072 16.1 0.1 4 7.1 0.0 3.8 4 0 0 4 4 4 1 IstB-like ATP binding protein NACHT PF05729.12 EPS30565.1 - 0.012 15.6 0.3 1.5 8.7 0.1 2.7 2 0 0 2 2 2 0 NACHT domain SbcCD_C PF13558.6 EPS30565.1 - 0.015 15.5 0.1 12 6.2 0.0 3.7 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF3987 PF13148.6 EPS30565.1 - 0.044 12.8 0.1 1.4 7.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_24 PF13479.6 EPS30565.1 - 0.053 13.3 1.5 10 5.8 0.0 2.9 2 1 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EPS30565.1 - 0.058 13.1 0.0 3.8 7.2 0.0 2.6 3 0 0 3 3 2 0 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.18 EPS30565.1 - 0.071 12.5 0.0 4.3 6.6 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.17 EPS30565.1 - 0.073 13.2 3.6 0.29 11.2 0.1 2.6 3 0 0 3 3 2 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 EPS30565.1 - 0.081 13.0 0.1 2.4 8.3 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.22 EPS30565.1 - 0.1 13.0 0.0 31 5.0 0.0 2.9 2 0 0 2 2 2 0 RNA helicase NB-ARC PF00931.22 EPS30565.1 - 0.11 11.6 0.6 4.2 6.5 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Gtr1_RagA PF04670.12 EPS30565.1 - 0.12 11.7 0.0 7.6 5.8 0.0 2.6 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region APS_kinase PF01583.20 EPS30565.1 - 0.18 11.7 0.1 20 5.0 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase CbiA PF01656.23 EPS30565.1 - 0.26 11.3 1.8 24 5.0 0.3 2.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain PhoH PF02562.16 EPS30565.1 - 0.44 10.0 2.1 34 3.8 0.3 3.1 3 0 0 3 3 3 0 PhoH-like protein ATPase PF06745.13 EPS30565.1 - 1 8.7 7.4 1.5 8.1 0.3 3.3 4 0 0 4 4 4 0 KaiC Polysacc_synt_4 PF04669.13 EPS30566.1 - 1.6e-20 73.5 1.8 4.6e-19 68.7 1.8 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis Ric8 PF10165.9 EPS30567.1 - 7.3e-116 387.9 0.0 8.4e-116 387.7 0.0 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Rif1_N PF12231.8 EPS30568.1 - 9.9e-139 462.5 1.7 1.5e-138 461.9 1.7 1.3 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Aldo_ket_red PF00248.21 EPS30569.1 - 5.6e-47 160.4 0.0 6.9e-47 160.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PUA PF01472.20 EPS30569.1 - 0.039 13.9 0.1 0.086 12.8 0.1 1.6 1 0 0 1 1 1 0 PUA domain Aldose_epim PF01263.20 EPS30570.1 - 5.9e-40 137.4 0.1 7.4e-40 137.1 0.1 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase CARDB PF07705.11 EPS30570.1 - 0.0083 16.4 1.7 0.011 16.0 0.8 1.6 2 0 0 2 2 2 1 CARDB AA_permease_2 PF13520.6 EPS30571.1 - 1.5e-50 172.3 45.9 1.9e-50 172.0 45.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPS30571.1 - 1e-18 67.2 37.3 1.5e-18 66.7 37.3 1.1 1 0 0 1 1 1 1 Amino acid permease Bac_thur_toxin PF01338.18 EPS30572.1 - 0.092 12.2 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 Bacillus thuringiensis toxin Glyco_hydro_15 PF00723.21 EPS30575.1 - 2.8e-97 326.3 0.0 3.3e-97 326.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 EPS30575.1 - 1.7e-26 91.9 0.0 3.4e-26 91.0 0.0 1.5 1 0 0 1 1 1 1 Starch binding domain UBA_4 PF14555.6 EPS30576.1 - 0.009 15.8 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain DNApol_Exo PF18136.1 EPS30576.1 - 0.077 12.1 1.2 0.095 11.8 1.2 1.1 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain DAHP_synth_2 PF01474.16 EPS30577.1 - 1.9e-201 669.3 0.0 2.2e-201 669.1 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family DUF5583 PF17821.1 EPS30578.1 - 0.0041 17.1 0.1 0.0041 17.1 0.1 2.9 3 0 0 3 3 3 1 Family of unknown function (DUF5583) SWIRM-assoc_2 PF16496.5 EPS30578.1 - 0.51 9.1 0.0 0.51 9.1 0.0 3.4 4 1 0 4 4 4 0 SWIRM-associated domain at the N-terminal adh_short PF00106.25 EPS30579.1 - 7.1e-23 81.1 0.0 3.5e-22 78.8 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS30579.1 - 5.4e-14 52.3 0.0 9.8e-14 51.5 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EPS30579.1 - 2e-07 30.7 0.0 5.7e-07 29.2 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EPS30579.1 - 0.00023 20.7 0.1 0.00058 19.4 0.1 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase KR PF08659.10 EPS30579.1 - 0.01 15.8 0.1 0.019 14.9 0.1 1.3 1 0 0 1 1 1 0 KR domain adh_short_C2 PF13561.6 EPS30580.1 - 2.2e-58 197.6 0.2 2.6e-58 197.3 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPS30580.1 - 2.9e-49 167.2 1.1 3.8e-49 166.8 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPS30580.1 - 5.7e-14 52.4 0.5 7.8e-14 52.0 0.5 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPS30580.1 - 0.00011 21.7 0.0 0.00014 21.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 EPS30580.1 - 0.019 14.3 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 EPS30580.1 - 0.022 14.2 0.0 0.072 12.5 0.0 1.8 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase NAD_binding_7 PF13241.6 EPS30580.1 - 0.048 14.1 0.0 0.09 13.2 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding PTR2 PF00854.21 EPS30582.1 - 3.5e-81 273.1 5.6 4.7e-81 272.6 5.6 1.1 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 EPS30582.1 - 6.6e-08 31.9 20.3 3.3e-07 29.5 19.5 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily PASTA PF03793.19 EPS30582.1 - 0.098 12.5 0.1 7.6 6.5 0.0 2.8 3 0 0 3 3 3 0 PASTA domain SR-25 PF10500.9 EPS30583.1 - 0.74 9.4 6.3 1.2 8.6 6.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RVT_2 PF07727.14 EPS30584.1 - 5e-07 29.6 0.0 6.6e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PLA2_B PF01735.18 EPS30585.1 - 8.3e-201 667.6 2.7 9.8e-201 667.4 2.7 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain IBR PF01485.21 EPS30585.1 - 0.054 13.7 1.2 0.099 12.9 1.2 1.3 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain mRNA_triPase PF02940.15 EPS30586.1 - 6.9e-63 212.3 0.2 1e-62 211.7 0.2 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Acyl_transf_3 PF01757.22 EPS30587.1 - 5e-33 114.6 39.7 8.9e-33 113.8 39.7 1.4 1 1 0 1 1 1 1 Acyltransferase family UPF0182 PF03699.13 EPS30587.1 - 0.11 10.6 2.7 0.14 10.2 2.4 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0182) WD40 PF00400.32 EPS30588.1 - 4.3e-14 52.7 7.4 1.4e-05 25.7 0.0 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat CTP_transf_like PF01467.26 EPS30589.1 - 1.5e-06 28.5 0.0 3.6e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 Cytidylyltransferase-like F-box-like PF12937.7 EPS30591.1 - 0.0037 17.1 0.0 0.016 15.1 0.0 2.2 1 1 0 1 1 1 1 F-box-like His_Phos_2 PF00328.22 EPS30592.1 - 3.3e-79 267.0 0.0 4e-79 266.7 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF16 PF01519.16 EPS30593.1 - 0.071 13.6 2.1 0.12 12.8 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 UPF0449 PF15136.6 EPS30593.1 - 0.071 13.6 1.9 0.2 12.1 1.9 1.8 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 zf-C4H2 PF10146.9 EPS30593.1 - 0.11 12.8 0.2 0.11 12.8 0.2 2.6 2 0 0 2 2 2 0 Zinc finger-containing protein Remorin_C PF03763.13 EPS30593.1 - 0.12 12.3 7.0 0.21 11.5 7.0 1.3 1 0 0 1 1 1 0 Remorin, C-terminal region NAPRTase_N PF17767.1 EPS30593.1 - 0.27 11.6 1.8 0.43 11.0 1.8 1.2 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Nucleo_P87 PF07267.11 EPS30593.1 - 0.39 9.5 4.8 0.2 10.5 2.8 1.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 bZIP_2 PF07716.15 EPS30593.1 - 1.3 9.2 14.8 1.9 8.6 13.9 1.7 1 1 0 1 1 1 0 Basic region leucine zipper SlyX PF04102.12 EPS30593.1 - 2.8 8.6 9.3 0.79 10.4 3.3 2.6 2 0 0 2 2 2 0 SlyX SGL PF08450.12 EPS30595.1 - 1.2e-77 260.9 0.0 1.4e-77 260.6 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Aldedh PF00171.22 EPS30596.1 - 2.5e-186 619.7 0.4 2.8e-186 619.6 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EPS30596.1 - 0.00085 18.8 0.0 0.0018 17.8 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) DUF5133 PF17196.4 EPS30596.1 - 0.64 10.3 4.5 7.6 6.8 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF5133) EVE PF01878.18 EPS30597.1 - 1.3e-48 164.7 0.1 2e-48 164.1 0.1 1.3 1 0 0 1 1 1 1 EVE domain AT_hook PF02178.19 EPS30597.1 - 1.1e-08 34.0 66.8 0.05 13.5 5.0 7.1 6 0 0 6 6 6 6 AT hook motif AhpC-TSA PF00578.21 EPS30598.1 - 8.4e-32 109.7 0.0 1.6e-31 108.8 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EPS30598.1 - 6.9e-14 51.8 0.0 9e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EPS30598.1 - 3.3e-13 49.2 0.5 5.3e-13 48.6 0.5 1.3 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Kelch_4 PF13418.6 EPS30599.1 - 2.8e-18 65.6 0.5 1.6e-06 28.0 0.0 5.3 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_3 PF13415.6 EPS30599.1 - 4.1e-15 55.6 4.2 3.2e-09 36.9 0.0 5.6 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EPS30599.1 - 3.2e-13 49.4 6.6 1.4e-05 24.9 0.0 4.5 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 EPS30599.1 - 4.5e-12 45.4 0.2 0.021 14.4 0.0 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.6 EPS30599.1 - 2e-10 40.6 5.9 0.094 13.0 0.0 5.5 4 1 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 EPS30599.1 - 9.1e-10 38.1 0.1 0.005 16.8 0.0 4.5 3 1 0 3 3 3 3 Kelch motif BTB PF00651.31 EPS30599.1 - 0.076 13.3 0.0 4.3 7.6 0.0 2.3 2 0 0 2 2 2 0 BTB/POZ domain Ribophorin_II PF05817.14 EPS30602.1 - 4.7e-27 94.8 0.1 6e-27 94.5 0.1 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II DUF5377 PF17347.2 EPS30602.1 - 0.07 13.5 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5377) ADH_N PF08240.12 EPS30604.1 - 5.3e-19 68.1 6.4 9.8e-19 67.2 6.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPS30604.1 - 4.1e-13 49.4 0.0 6.7e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EPS30604.1 - 0.0001 21.8 0.1 0.00017 21.0 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EPS30604.1 - 0.0011 18.3 0.0 0.0019 17.5 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 EPS30604.1 - 0.028 14.3 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.21 EPS30604.1 - 0.17 11.2 1.0 0.29 10.5 1.0 1.2 1 0 0 1 1 1 0 ThiF family Sulfatase PF00884.23 EPS30606.1 - 3.8e-19 69.2 0.5 5.9e-19 68.6 0.5 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EPS30606.1 - 1.1e-07 31.8 0.0 1.9e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 EPS30606.1 - 0.00014 20.6 0.1 0.00019 20.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Fungal_trans_2 PF11951.8 EPS30607.1 - 6.8e-08 31.7 1.6 1.7e-05 23.9 0.2 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain MFS_1 PF07690.16 EPS30609.1 - 1.3e-26 93.4 24.7 1.3e-26 93.4 24.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS30609.1 - 7.7e-14 51.4 8.0 7.7e-14 51.4 8.0 3.1 2 2 1 3 3 3 2 Sugar (and other) transporter DUF3237 PF11578.8 EPS30610.1 - 4.5e-33 114.2 0.0 5.3e-33 114.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Amidase PF01425.21 EPS30611.1 - 1.8e-99 333.8 0.0 2.3e-99 333.4 0.0 1.1 1 0 0 1 1 1 1 Amidase NAD_binding_4 PF07993.12 EPS30612.1 - 2.6e-37 128.4 0.0 3.7e-37 127.9 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EPS30612.1 - 1.9e-30 105.8 0.0 4.8e-30 104.5 0.0 1.5 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.21 EPS30612.1 - 1e-14 54.6 0.0 1.7e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EPS30612.1 - 1.1e-05 25.0 0.0 2.3e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase PP-binding PF00550.25 EPS30612.1 - 2.6e-05 24.5 0.3 6e-05 23.3 0.3 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 EPS30612.1 - 0.00031 19.8 0.0 0.00053 19.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 EPS30612.1 - 0.0092 15.6 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family DapB_N PF01113.20 EPS30612.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.6 EPS30612.1 - 0.12 12.3 0.1 0.29 11.0 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H-binding KR PF08659.10 EPS30612.1 - 0.15 12.0 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 KR domain CTD PF12815.7 EPS30613.1 - 1.9e-34 118.1 48.8 1e-20 74.1 17.7 4.1 1 1 3 4 4 4 3 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5-NGN PF03439.13 EPS30613.1 - 1.3e-18 66.6 0.0 2.2e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 EPS30613.1 - 4.3e-17 62.9 10.9 4.3e-17 62.9 10.9 3.7 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.29 EPS30613.1 - 1.2e-11 44.1 7.3 0.0019 18.1 0.0 4.9 5 0 0 5 5 5 3 KOW motif DUF3912 PF13051.6 EPS30613.1 - 0.1 12.9 0.9 5.3 7.4 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3912) TFIIF_alpha PF05793.12 EPS30613.1 - 4.9 5.6 36.5 7.2 5.1 36.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Acyl-CoA_dh_1 PF00441.24 EPS30614.1 - 1.6e-41 142.0 0.6 2.3e-41 141.5 0.6 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EPS30614.1 - 9.5e-22 77.0 0.1 1.7e-21 76.2 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.28 EPS30614.1 - 3.9e-19 68.6 0.3 7.6e-19 67.6 0.3 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.16 EPS30614.1 - 1.1e-18 67.9 0.0 2.4e-18 66.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EPS30614.1 - 1.3e-08 35.2 0.0 2.1e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain RPN2_C PF18004.1 EPS30616.1 - 1.2e-54 184.6 6.4 1.2e-54 184.6 6.4 2.1 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 EPS30616.1 - 3e-36 122.0 26.0 7.9e-10 38.7 0.1 9.1 9 0 0 9 9 9 7 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EPS30616.1 - 3.7e-21 75.3 0.5 1.6e-14 54.1 0.0 5.2 4 1 2 6 6 6 4 HEAT repeats HEAT_EZ PF13513.6 EPS30616.1 - 3e-07 30.8 0.1 6.2e-05 23.4 0.1 4.6 3 1 1 4 4 4 2 HEAT-like repeat HEAT PF02985.22 EPS30616.1 - 2.8e-05 24.0 0.1 5.5 7.5 0.0 5.0 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 EPS30616.1 - 0.0031 17.6 0.4 0.21 11.6 0.0 3.2 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_PBS PF03130.16 EPS30616.1 - 0.075 13.7 2.0 1.1 10.2 0.0 3.9 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat LMBR1 PF04791.16 EPS30617.1 - 0.012 14.5 1.4 0.016 14.2 1.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein MSC PF09402.10 EPS30617.1 - 0.087 12.3 0.6 0.14 11.6 0.3 1.4 1 1 0 1 1 1 0 Man1-Src1p-C-terminal domain Jnk-SapK_ap_N PF09744.9 EPS30617.1 - 0.24 11.6 8.8 13 6.0 8.5 2.8 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 TPR_MLP1_2 PF07926.12 EPS30617.1 - 0.32 11.1 10.0 2.8 8.0 3.9 2.8 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Seryl_tRNA_N PF02403.22 EPS30617.1 - 0.33 11.2 6.2 1.3 9.3 1.9 2.8 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF724 PF05266.14 EPS30617.1 - 0.37 10.6 4.6 0.71 9.7 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) CENP-H PF05837.12 EPS30617.1 - 0.42 11.0 10.9 0.075 13.4 1.7 3.3 2 1 1 3 3 3 0 Centromere protein H (CENP-H) CEP209_CC5 PF16574.5 EPS30617.1 - 0.81 9.9 8.5 18 5.5 0.7 3.4 2 1 1 3 3 3 0 Coiled-coil region of centrosome protein CE290 DUF465 PF04325.13 EPS30617.1 - 1.2 9.2 7.1 4.8 7.3 0.3 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF465) APG6_N PF17675.1 EPS30617.1 - 3.4 8.2 16.8 0.76 10.3 3.3 3.2 2 1 1 3 3 3 0 Apg6 coiled-coil region Fib_alpha PF08702.10 EPS30617.1 - 4.7 7.4 5.2 2.2 8.5 0.2 2.5 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family Abhydrolase_1 PF00561.20 EPS30618.1 - 0.0077 15.9 0.5 1.5 8.4 0.9 2.5 2 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EPS30618.1 - 0.026 13.8 0.3 0.071 12.4 0.2 1.6 2 1 0 2 2 2 0 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 EPS30618.1 - 0.045 13.3 0.0 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF3336 PF11815.8 EPS30619.1 - 2e-33 115.0 0.4 4.3e-33 113.9 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EPS30619.1 - 1.6e-21 77.4 0.2 6.3e-21 75.5 0.0 2.0 2 0 0 2 2 2 1 Patatin-like phospholipase PilS PF08805.11 EPS30619.1 - 0.17 11.7 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 PilS N terminal PMI_typeI PF01238.21 EPS30621.1 - 2.3e-69 234.4 0.0 6.4e-68 229.6 0.0 2.0 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 EPS30621.1 - 0.00062 19.4 0.0 0.12 12.1 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Glyphos_transf PF04464.14 EPS30621.1 - 0.095 11.7 0.0 0.29 10.1 0.0 1.7 2 0 0 2 2 2 0 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase Cupin_3 PF05899.12 EPS30621.1 - 0.2 11.3 0.3 15 5.4 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF861) YL1 PF05764.13 EPS30625.1 - 0.058 13.5 0.9 0.08 13.0 0.9 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Med8 PF10232.9 EPS30627.1 - 5.6e-57 193.0 0.0 6.2e-57 192.9 0.0 1.0 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 YPEB PF14620.6 EPS30627.1 - 0.0063 15.9 0.0 0.0078 15.6 0.0 1.2 1 0 0 1 1 1 1 YpeB sporulation NOA36 PF06524.12 EPS30627.1 - 0.58 9.4 2.7 0.74 9.1 2.7 1.1 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 EPS30627.1 - 2.2 6.3 3.5 3 5.9 3.5 1.2 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 EPS30627.1 - 7 7.1 9.7 13 6.2 9.7 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PQ-loop PF04193.14 EPS30628.1 - 7.3e-20 70.5 8.4 6.6e-11 41.8 1.0 2.9 3 0 0 3 3 3 2 PQ loop repeat DUF4383 PF14325.6 EPS30628.1 - 0.0069 16.7 6.3 0.0085 16.4 4.6 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4383) DoxX_3 PF13781.6 EPS30628.1 - 0.13 13.0 3.4 0.23 12.1 2.1 2.0 2 0 0 2 2 2 0 DoxX-like family UbiA PF01040.18 EPS30629.1 - 7e-56 189.3 19.3 7e-56 189.3 19.3 1.3 1 1 0 1 1 1 1 UbiA prenyltransferase family tRNA-synt_2 PF00152.20 EPS30630.1 - 1.1e-92 310.5 0.0 1.5e-92 310.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EPS30630.1 - 0.00068 19.6 0.0 0.0017 18.3 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.25 EPS30630.1 - 0.0092 16.0 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ALC PF17527.2 EPS30630.1 - 0.097 12.3 0.0 0.41 10.3 0.0 1.9 2 0 0 2 2 2 0 Phage ALC protein ABC_tran PF00005.27 EPS30631.1 - 1.3e-46 158.5 0.0 9.7e-30 103.9 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 EPS30631.1 - 3.8e-39 135.0 33.7 9.5e-28 97.6 12.9 3.0 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.19 EPS30631.1 - 8.1e-10 38.5 0.7 0.032 13.7 0.1 4.9 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 EPS30631.1 - 0.00013 21.1 0.0 0.065 12.3 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein MMR_HSR1 PF01926.23 EPS30631.1 - 0.00027 21.0 0.1 0.062 13.4 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.6 EPS30631.1 - 0.00048 19.8 0.3 0.5 10.2 0.1 3.0 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EPS30631.1 - 0.00049 20.4 0.2 3.4 7.9 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EPS30631.1 - 0.00088 19.7 6.0 0.13 12.7 0.2 3.8 2 1 1 3 3 3 1 AAA ATPase domain DUF87 PF01935.17 EPS30631.1 - 0.0015 18.7 3.0 0.45 10.6 0.0 3.3 3 0 0 3 3 3 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 EPS30631.1 - 0.0036 17.2 0.0 3.8 7.4 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase DUF2075 PF09848.9 EPS30631.1 - 0.013 14.8 0.2 0.24 10.6 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 EPS30631.1 - 0.015 15.0 0.5 31 4.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 EPS30631.1 - 0.032 14.0 0.2 0.48 10.1 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_25 PF13481.6 EPS30631.1 - 0.039 13.5 0.0 3.2 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 EPS30631.1 - 0.046 13.4 0.0 0.25 11.1 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.7 EPS30631.1 - 0.09 11.7 0.1 0.71 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain MeaB PF03308.16 EPS30631.1 - 0.1 11.5 0.1 0.23 10.4 0.1 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 EPS30631.1 - 0.11 12.5 0.9 1.9 8.6 0.0 2.9 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain NB-ARC PF00931.22 EPS30631.1 - 0.12 11.5 0.1 7.6 5.6 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain AAA_7 PF12775.7 EPS30631.1 - 0.21 11.1 0.2 6.4 6.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region OMP_b-brl_2 PF13568.6 EPS30631.1 - 0.22 11.6 0.0 0.43 10.6 0.0 1.5 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain AAA_23 PF13476.6 EPS30631.1 - 0.25 11.8 7.8 0.64 10.5 0.0 3.6 4 0 0 4 4 4 0 AAA domain CPSF100_C PF13299.6 EPS30631.1 - 0.53 10.4 2.1 13 5.9 0.0 2.8 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DUF4834 PF16118.5 EPS30631.1 - 0.8 10.7 2.5 2.9 8.9 0.0 3.2 3 0 0 3 3 1 0 Domain of unknown function (DUF4834) LigD_N PF13298.6 EPS30632.1 - 8.5e-36 122.4 0.1 1.9e-35 121.3 0.1 1.6 1 0 0 1 1 1 1 DNA polymerase Ligase (LigD) FAD_binding_4 PF01565.23 EPS30633.1 - 1.2e-27 96.4 2.1 1.8e-27 95.8 2.1 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EPS30633.1 - 1.4e-11 44.2 0.0 4.1e-11 42.8 0.0 1.8 2 0 0 2 2 2 1 Berberine and berberine like Sulf_transp PF04143.14 EPS30634.1 - 4.5e-05 23.2 4.7 4.5e-05 23.2 4.7 2.9 2 1 0 2 2 2 2 Sulphur transport Peptidase_M28 PF04389.17 EPS30635.1 - 1.6e-32 112.8 0.1 2.1e-32 112.4 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 Sigma70_r4_2 PF08281.12 EPS30637.1 - 0.1 12.3 0.3 0.21 11.3 0.3 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 DUF5549 PF17703.1 EPS30638.1 - 0.026 14.2 2.6 0.036 13.7 2.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5549) FoP_duplication PF13865.6 EPS30638.1 - 0.072 13.7 7.2 0.13 12.8 7.2 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 FXMRP1_C_core PF12235.8 EPS30638.1 - 0.65 10.7 6.8 0.96 10.1 6.7 1.4 1 1 0 1 1 1 0 Fragile X-related 1 protein core C terminal MutS_V PF00488.21 EPS30639.1 - 1.6e-66 223.9 0.3 3e-66 223.1 0.3 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EPS30639.1 - 5e-39 134.5 0.0 1.1e-38 133.4 0.0 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EPS30639.1 - 2.5e-32 111.4 0.0 5.3e-32 110.4 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.18 EPS30639.1 - 2.2e-13 50.3 0.4 4.8e-13 49.3 0.4 1.6 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 EPS30639.1 - 9.5e-12 45.4 0.0 2.3e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 MutS domain II AAA_29 PF13555.6 EPS30639.1 - 0.061 13.1 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EPS30639.1 - 0.37 11.3 3.7 0.64 10.5 0.0 2.7 3 0 0 3 3 3 0 AAA domain Shugoshin_C PF07557.11 EPS30639.1 - 2.2 8.2 6.6 0.11 12.3 0.8 1.9 2 0 0 2 2 2 0 Shugoshin C terminus DEAD PF00270.29 EPS30640.1 - 2.7e-18 66.4 0.0 5.1e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EPS30640.1 - 2.2e-11 44.1 0.0 5.7e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EPS30640.1 - 1.9e-07 31.4 0.0 5.8e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.16 EPS30640.1 - 0.031 13.7 0.0 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein T2SSE PF00437.20 EPS30640.1 - 0.11 11.5 0.0 0.36 9.9 0.0 1.8 1 0 0 1 1 1 0 Type II/IV secretion system protein tRNA-synt_1b PF00579.25 EPS30641.1 - 1.4e-73 247.8 0.0 1.8e-73 247.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 EPS30641.1 - 1.6e-49 166.7 0.0 3.5e-49 165.6 0.0 1.6 2 0 0 2 2 2 1 Tyrosyl-tRNA synthetase C-terminal domain Raffinose_syn PF05691.12 EPS30642.1 - 1.8e-49 168.3 1.3 7.8e-48 162.8 2.0 2.3 2 1 0 2 2 2 1 Raffinose synthase or seed imbibition protein Sip1 Chordopox_A33R PF05966.12 EPS30642.1 - 0.066 12.5 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Chordopoxvirus A33R protein Acetyltransf_1 PF00583.25 EPS30643.1 - 5.9e-15 55.5 0.0 8.7e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EPS30643.1 - 4.1e-08 33.2 0.0 6.8e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EPS30643.1 - 1.6e-06 28.5 0.1 2.2e-06 28.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPS30643.1 - 7.1e-06 25.9 0.0 1.2e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 EPS30643.1 - 0.059 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PIG-U PF06728.13 EPS30644.1 - 2.7e-120 401.9 20.6 3.1e-120 401.8 20.6 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Mannosyl_trans PF05007.13 EPS30644.1 - 7.3e-05 22.8 1.5 0.00013 21.9 1.1 1.6 1 1 0 1 1 1 1 Mannosyltransferase (PIG-M) 8TM_micro PF17028.5 EPS30644.1 - 0.76 9.4 9.2 0.68 9.6 7.1 1.9 2 1 0 2 2 2 0 8TM Microsporidial transmembrane domain Pescadillo_N PF06732.11 EPS30645.1 - 4.7e-125 416.6 0.2 4.7e-125 416.6 0.2 1.7 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 EPS30645.1 - 5.7e-05 23.4 0.0 0.00042 20.7 0.0 2.3 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EPS30645.1 - 0.035 14.5 0.0 0.24 11.8 0.0 2.4 2 1 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 EPS30645.1 - 0.062 13.6 0.0 0.19 12.0 0.0 1.9 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain RRN9 PF10680.9 EPS30646.1 - 1.2e-15 57.5 2.5 1.2e-15 57.5 2.5 2.3 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor Macoilin PF09726.9 EPS30646.1 - 0.73 8.3 10.1 0.13 10.8 4.8 1.9 2 0 0 2 2 2 0 Macoilin family zf-C2H2 PF00096.26 EPS30646.1 - 2 9.0 3.9 6.2 7.5 3.1 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type Hid1 PF12722.7 EPS30646.1 - 8.4 4.4 5.4 11 4.0 5.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Aldedh PF00171.22 EPS30647.1 - 1.8e-168 560.9 0.6 2e-168 560.7 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family bZIP_1 PF00170.21 EPS30650.1 - 1.5e-07 31.4 3.9 3.2e-07 30.4 3.9 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EPS30650.1 - 0.00048 20.2 3.2 0.00088 19.3 3.2 1.4 1 0 0 1 1 1 1 Basic region leucine zipper YARHG PF13308.6 EPS30650.1 - 0.17 11.8 0.1 0.52 10.2 0.0 1.8 2 0 0 2 2 2 0 YARHG domain Pkinase PF00069.25 EPS30651.1 - 9.9e-69 231.6 0.0 1.2e-68 231.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS30651.1 - 3.9e-34 118.1 0.0 5.1e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EPS30651.1 - 2e-06 27.0 0.1 2.7e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EPS30651.1 - 4.3e-05 23.0 0.2 8.1e-05 22.1 0.2 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EPS30651.1 - 0.00059 19.2 0.1 0.002 17.5 0.0 1.8 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EPS30651.1 - 0.003 17.5 0.2 0.007 16.3 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EPS30651.1 - 0.013 15.2 0.1 0.026 14.1 0.1 1.5 1 1 0 1 1 1 0 RIO1 family FTA2 PF13095.6 EPS30651.1 - 0.013 15.2 0.0 0.039 13.6 0.0 1.7 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 EPS30651.1 - 0.12 12.0 0.2 0.2 11.2 0.2 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase MARVEL PF01284.23 EPS30652.1 - 1.2e-11 44.9 15.6 1.5e-11 44.5 15.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain HIG_1_N PF04588.13 EPS30653.1 - 1e-26 92.9 0.6 1.4e-26 92.4 0.6 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF2514 PF10721.9 EPS30653.1 - 0.0059 16.6 6.5 0.0088 16.1 6.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2514) MAS20 PF02064.15 EPS30653.1 - 0.034 14.2 1.4 0.077 13.1 1.4 1.6 1 0 0 1 1 1 0 MAS20 protein import receptor PALP PF00291.25 EPS30654.1 - 4.6e-76 256.0 0.1 6.2e-76 255.6 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 EPS30654.1 - 6.2e-43 144.5 0.0 3.3e-20 71.6 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Ribosomal_L36 PF00444.18 EPS30655.1 - 1.3e-20 73.3 9.4 1.8e-20 72.8 9.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L36 GTP_EFTU PF00009.27 EPS30656.1 - 5.7e-58 195.7 0.4 9.9e-58 194.9 0.4 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 EPS30656.1 - 4e-33 113.4 0.0 8.3e-33 112.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 EPS30656.1 - 6.1e-33 113.2 0.1 1.1e-32 112.4 0.1 1.4 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 EPS30656.1 - 9.5e-24 83.3 0.0 2.9e-23 81.7 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EPS30656.1 - 1.7e-13 50.7 0.1 4.3e-13 49.4 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EPS30656.1 - 1.6e-06 28.0 0.0 4.1e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain Mitofilin PF09731.9 EPS30659.1 - 1.6e-159 532.7 33.7 4.1e-131 438.8 26.7 2.0 1 1 1 2 2 2 2 Mitochondrial inner membrane protein YqhG PF11079.8 EPS30659.1 - 0.034 13.1 2.4 0.072 12.0 2.4 1.5 1 0 0 1 1 1 0 Bacterial protein YqhG of unknown function Sld5 PF05916.11 EPS30659.1 - 2.2 8.8 12.2 1.9 9.0 1.9 2.7 1 1 1 2 2 2 0 GINS complex protein F_actin_bind PF08919.10 EPS30659.1 - 2.8 8.1 7.7 3.9 7.6 1.4 2.7 1 1 2 3 3 3 0 F-actin binding Ras PF00071.22 EPS30660.1 - 5.4e-59 198.4 0.2 6.2e-59 198.2 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EPS30660.1 - 1.7e-36 125.1 0.1 3.5e-36 124.1 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPS30660.1 - 1.6e-14 53.7 0.0 2e-14 53.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EPS30660.1 - 2.8e-07 30.2 0.0 3.3e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EPS30660.1 - 1.2e-06 28.6 0.0 1.9e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EPS30660.1 - 2.2e-06 27.4 0.0 3.1e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EPS30660.1 - 2.2e-05 24.4 1.0 0.16 11.9 0.1 2.4 1 1 2 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 EPS30660.1 - 0.0094 16.3 0.2 0.021 15.2 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EPS30660.1 - 0.025 14.8 0.0 2.3 8.5 0.0 2.4 1 1 0 2 2 2 0 AAA domain Syja_N PF02383.18 EPS30661.1 - 4e-93 312.3 0.0 5e-93 311.9 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain TraQ PF09679.10 EPS30661.1 - 0.057 13.3 1.6 0.12 12.3 1.6 1.4 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin chaperone (TraQ) Mur_ligase_M PF08245.12 EPS30662.1 - 3.2e-07 30.5 0.3 0.00029 20.9 0.2 3.0 1 1 1 2 2 2 2 Mur ligase middle domain DUF2188 PF09954.9 EPS30662.1 - 0.15 12.2 0.7 0.5 10.5 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) NMT_C PF02799.15 EPS30663.1 - 6.6e-90 300.2 0.0 1.1e-89 299.5 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 EPS30663.1 - 1.2e-75 252.7 0.1 2.5e-74 248.5 0.0 2.1 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.7 EPS30663.1 - 3.5e-06 27.1 0.0 0.00018 21.6 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPS30663.1 - 0.023 14.9 0.0 0.042 14.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DUF3024 PF11225.8 EPS30663.1 - 0.11 12.8 1.0 7.1 7.0 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3024) TLD PF07534.16 EPS30664.1 - 4.1e-23 82.1 0.0 6.5e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 TLD Mito_fiss_reg PF05308.11 EPS30666.1 - 0.1 12.7 5.4 0.11 12.6 5.4 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 EPS30666.1 - 0.2 11.1 8.3 0.22 10.9 8.3 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 EPS30666.1 - 3.8 7.6 11.4 5.3 7.1 11.4 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Abhydrolase_6 PF12697.7 EPS30667.1 - 9.6e-08 32.9 1.0 1.4e-07 32.4 1.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPS30667.1 - 4.3e-06 26.2 0.1 1.8e-05 24.1 0.1 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EPS30667.1 - 0.00023 20.9 0.0 0.00037 20.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EPS30667.1 - 0.0041 17.0 0.0 0.0068 16.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Na_Pi_cotrans PF02690.15 EPS30667.1 - 0.0083 16.2 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 Na+/Pi-cotransporter DSBA PF01323.20 EPS30669.1 - 1.8e-18 67.0 0.0 2.1e-18 66.8 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain DUF4050 PF13259.6 EPS30670.1 - 0.17 12.2 8.1 0.22 11.8 8.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Pol_alpha_B_N PF08418.10 EPS30670.1 - 0.26 11.2 9.7 0.37 10.7 9.7 1.3 1 1 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Macoilin PF09726.9 EPS30670.1 - 5.8 5.3 10.3 6.8 5.1 10.3 1.0 1 0 0 1 1 1 0 Macoilin family cobW PF02492.19 EPS30671.1 - 2.2e-41 141.4 0.0 3.1e-41 140.9 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 EPS30671.1 - 0.0023 17.8 0.0 0.0065 16.4 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CobW_C PF07683.14 EPS30671.1 - 0.0031 17.4 0.0 0.31 11.0 0.0 2.7 3 0 0 3 3 3 1 Cobalamin synthesis protein cobW C-terminal domain AAA_22 PF13401.6 EPS30671.1 - 0.022 15.1 0.0 0.048 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EPS30671.1 - 0.064 13.0 0.0 1.1 9.1 0.0 2.6 3 0 0 3 3 3 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 EPS30671.1 - 0.067 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 EPS30671.1 - 0.13 12.7 0.0 0.34 11.3 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain ATPase_2 PF01637.18 EPS30671.1 - 0.21 11.5 0.0 1.4 8.8 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Orn_Arg_deC_N PF02784.16 EPS30672.1 - 6.7e-82 274.6 0.0 8.6e-82 274.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EPS30672.1 - 7.3e-20 71.0 0.0 1.2e-19 70.4 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Methyltransf_16 PF10294.9 EPS30673.1 - 2.1e-51 174.1 0.0 3.4e-51 173.4 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EPS30673.1 - 0.00012 21.9 0.0 0.0002 21.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPS30673.1 - 0.0017 19.0 0.0 0.0046 17.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EPS30673.1 - 0.0085 15.7 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EPS30673.1 - 0.033 13.6 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 EPS30673.1 - 0.096 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_12 PF08242.12 EPS30673.1 - 0.13 13.0 0.0 0.26 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Zn_clus PF00172.18 EPS30675.1 - 9.9e-06 25.6 10.9 1.6e-05 24.9 10.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain M16C_assoc PF08367.11 EPS30676.1 - 1.9e-73 246.7 0.2 2.8e-73 246.1 0.2 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 EPS30676.1 - 2.7e-21 76.4 0.0 1.4e-15 57.8 0.0 2.8 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EPS30676.1 - 6e-10 39.3 0.0 6.7e-09 35.9 0.0 2.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) ComX PF05952.12 EPS30676.1 - 0.085 12.8 0.1 12 6.0 0.1 3.5 3 0 0 3 3 3 0 Bacillus competence pheromone ComX Taxilin PF09728.9 EPS30677.1 - 2.3e-92 309.5 50.4 2.3e-92 309.5 50.4 1.7 1 1 1 2 2 2 1 Myosin-like coiled-coil protein DUF4201 PF13870.6 EPS30677.1 - 7.2e-05 22.6 14.4 7.2e-05 22.6 14.4 3.8 2 2 1 3 3 3 1 Domain of unknown function (DUF4201) ERM PF00769.19 EPS30677.1 - 0.012 15.4 17.8 0.012 15.4 17.8 2.7 1 1 0 2 2 2 0 Ezrin/radixin/moesin family UPF0242 PF06785.11 EPS30677.1 - 0.33 11.0 52.3 0.19 11.8 14.3 3.6 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus SLATT_4 PF18186.1 EPS30677.1 - 2.3 7.8 15.6 0.43 10.2 1.7 3.3 2 1 1 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 4 TMF_TATA_bd PF12325.8 EPS30677.1 - 2.6 8.3 50.8 4.7 7.5 1.5 4.3 2 2 2 4 4 4 0 TATA element modulatory factor 1 TATA binding Laminin_II PF06009.12 EPS30677.1 - 3 7.8 35.0 3.6 7.6 6.3 4.1 1 1 3 4 4 4 0 Laminin Domain II DUF3450 PF11932.8 EPS30677.1 - 6.2 6.0 45.2 0.3 10.4 9.3 4.0 2 2 2 4 4 4 0 Protein of unknown function (DUF3450) DUF4298 PF14131.6 EPS30677.1 - 9.5 6.3 19.6 0.052 13.5 2.8 4.4 2 2 2 4 4 4 0 Domain of unknown function (DUF4298) Exonuc_VII_L PF02601.15 EPS30677.1 - 9.7 5.7 38.2 2 7.9 16.6 2.2 1 1 0 2 2 2 0 Exonuclease VII, large subunit NMO PF03060.15 EPS30678.1 - 3.2e-53 181.3 1.4 4.4e-53 180.8 1.4 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EPS30678.1 - 2.6e-08 33.2 0.3 3.4e-07 29.6 0.3 2.2 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EPS30678.1 - 0.0046 16.0 2.5 0.0077 15.3 2.5 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DNA_pol_E_B PF04042.16 EPS30679.1 - 4.4e-43 147.1 0.0 6.1e-43 146.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 EPS30679.1 - 2.7e-37 127.8 0.0 3.9e-37 127.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain Abhydrolase_6 PF12697.7 EPS30679.1 - 0.0044 17.6 0.5 0.01 16.5 0.5 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Acetyltransf_3 PF13302.7 EPS30680.1 - 1.1e-21 77.9 0.0 1.5e-21 77.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EPS30680.1 - 0.00026 20.7 1.4 1.1 8.9 0.0 2.9 3 0 0 3 3 3 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPS30680.1 - 0.024 14.6 0.1 0.58 10.2 0.0 2.2 2 0 0 2 2 2 0 FR47-like protein Glyco_hydro_61 PF03443.14 EPS30681.1 - 1.5e-69 234.0 0.2 1.9e-69 233.7 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 GSu_C4xC__C2xCH PF09698.10 EPS30681.1 - 4.8 8.0 7.3 1.5 9.6 0.8 3.1 3 0 0 3 3 3 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) DAGK_prokar PF01219.19 EPS30682.1 - 0.076 12.9 1.7 0.085 12.7 0.1 1.7 2 0 0 2 2 2 0 Prokaryotic diacylglycerol kinase HemY_N PF07219.13 EPS30682.1 - 0.21 11.8 5.1 0.22 11.7 0.5 2.1 2 0 0 2 2 2 0 HemY protein N-terminus Ribosomal_L38e PF01781.18 EPS30683.1 - 4.5e-32 109.9 2.4 5.4e-32 109.7 2.4 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family HipN PF18253.1 EPS30683.1 - 0.13 12.0 0.2 0.72 9.6 0.0 2.0 2 0 0 2 2 2 0 Hsp70-interacting protein N N-terminal domain Ish1 PF10281.9 EPS30685.1 - 4.2e-09 36.6 0.5 6.8e-09 35.9 0.5 1.4 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein SAP PF02037.27 EPS30685.1 - 0.061 13.1 1.0 0.53 10.1 1.0 2.1 1 1 0 1 1 1 0 SAP domain NTF2 PF02136.20 EPS30686.1 - 8.3e-06 26.4 0.1 2.6e-05 24.7 0.1 1.7 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 EPS30686.1 - 6.5e-05 22.9 0.1 0.00046 20.2 0.1 2.0 1 1 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 tRNA-synt_1g PF09334.11 EPS30687.1 - 3.2e-95 319.2 1.1 1.4e-93 313.7 0.7 2.5 2 1 0 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EPS30687.1 - 1.6e-23 82.8 0.1 2.4e-11 42.6 0.0 3.0 2 1 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 EPS30687.1 - 8.2e-12 45.1 0.0 1.9e-06 27.5 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 EPS30687.1 - 0.001 19.0 0.0 0.0022 18.0 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA PALP PF00291.25 EPS30688.1 - 2.2e-47 161.9 9.7 8.4e-46 156.7 7.8 2.5 2 1 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme PPTA PF01239.22 EPS30689.1 - 9.6e-32 107.8 23.6 6e-08 32.2 1.3 5.6 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat DUF1266 PF06889.11 EPS30689.1 - 0.013 15.6 1.0 0.037 14.1 1.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) TPR_14 PF13428.6 EPS30689.1 - 0.11 13.4 0.3 0.61 11.1 0.0 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF4269 PF14091.6 EPS30689.1 - 0.13 12.4 0.1 0.23 11.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4269) DUF924 PF06041.11 EPS30690.1 - 3.2e-55 187.1 0.1 4e-55 186.7 0.1 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Fungal_trans_2 PF11951.8 EPS30691.1 - 1.3e-27 96.6 1.4 1.8e-18 66.5 0.3 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS30691.1 - 2.5e-08 33.9 7.8 4.5e-08 33.1 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GHMP_kinases_N PF00288.26 EPS30692.1 - 1.2e-15 57.4 0.0 2.7e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EPS30692.1 - 6.9e-06 26.3 0.0 3.4e-05 24.1 0.0 2.2 3 0 0 3 3 3 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.9 EPS30692.1 - 0.00066 19.2 0.1 0.0013 18.3 0.1 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature AA_permease PF00324.21 EPS30693.1 - 4e-61 207.1 31.0 4.9e-61 206.8 31.0 1.1 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 EPS30693.1 - 8.8e-21 74.4 0.3 2e-08 33.7 0.1 3.3 3 0 0 3 3 3 3 Solute carrier family 12 Aa_trans PF01490.18 EPS30694.1 - 6.4e-81 272.1 28.6 7.6e-81 271.9 28.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MPC PF03650.13 EPS30695.1 - 3.3e-36 123.8 0.1 4e-36 123.5 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers MtN3_slv PF03083.16 EPS30695.1 - 0.1 12.7 0.4 0.13 12.3 0.4 1.2 1 0 0 1 1 1 0 Sugar efflux transporter for intercellular exchange LSM PF01423.22 EPS30696.1 - 2.2e-19 68.9 0.0 2.7e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain Ribosomal_L5_C PF00673.21 EPS30697.1 - 4.8e-22 77.9 0.0 7.2e-22 77.4 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EPS30697.1 - 2.4e-20 72.6 0.0 7.5e-20 71.0 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 HTH_ABP1_N PF18107.1 EPS30697.1 - 0.11 12.2 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain CPSase_L_D2 PF02786.17 EPS30699.1 - 1.4e-80 269.8 0.2 2.2e-80 269.1 0.2 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 EPS30699.1 - 2.6e-68 229.7 0.0 4.5e-68 228.9 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 EPS30699.1 - 8e-39 132.6 0.0 1.6e-38 131.6 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EPS30699.1 - 6.7e-31 106.6 0.0 1.6e-30 105.4 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 EPS30699.1 - 1e-27 97.4 0.0 1.8e-27 96.5 0.0 1.4 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 EPS30699.1 - 1.4e-17 63.2 3.8 1.7e-17 63.0 1.2 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EPS30699.1 - 8.3e-11 41.6 0.9 8.7e-05 22.3 0.0 3.5 2 1 1 3 3 3 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 EPS30699.1 - 5.9e-10 39.0 0.0 1.2e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EPS30699.1 - 1.4e-07 31.3 0.1 2.8e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EPS30699.1 - 3.3e-05 24.0 0.0 7.2e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 EPS30699.1 - 0.00051 19.7 0.0 0.0011 18.6 0.0 1.5 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 EPS30699.1 - 0.0034 17.0 0.0 0.0079 15.8 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 EPS30699.1 - 0.0069 15.6 0.0 0.23 10.7 0.0 2.3 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 EPS30699.1 - 0.0091 16.7 0.3 13 6.5 0.0 3.9 4 0 0 4 4 4 0 HlyD family secretion protein GARS_A PF01071.19 EPS30699.1 - 0.043 13.6 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Clathrin PF00637.20 EPS30700.1 - 3.6e-198 649.4 34.1 1.7e-31 109.0 0.5 7.4 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 EPS30700.1 - 3.2e-40 134.5 0.2 1.2e-08 34.8 0.1 6.7 6 0 0 6 6 6 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 EPS30700.1 - 5.2e-31 106.4 1.1 2.8e-30 104.0 0.1 2.9 2 0 0 2 2 2 1 Clathrin-H-link TPR_14 PF13428.6 EPS30700.1 - 0.00057 20.5 4.5 5.2 8.2 0.0 6.8 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_8 PF13181.6 EPS30700.1 - 0.0029 17.7 3.0 1.8 9.0 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 EPS30700.1 - 0.0047 16.9 2.4 48 4.3 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 EPS30700.1 - 0.067 13.5 0.7 40 4.6 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EPS30700.1 - 0.17 12.1 1.3 17 5.8 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Coatomer_WDAD PF04053.14 EPS30700.1 - 0.33 9.9 7.6 0.18 10.8 0.4 3.7 4 0 0 4 4 4 0 Coatomer WD associated region MFS_1 PF07690.16 EPS30701.1 - 1.1e-32 113.3 47.5 3.2e-31 108.6 24.3 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS30701.1 - 5.5e-29 101.3 25.6 5.6e-28 98.0 25.6 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter Cation_ATPase_C PF00689.21 EPS30701.1 - 4.9 6.8 9.7 7.1 6.3 1.7 2.8 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus TPMT PF05724.11 EPS30702.1 - 6.6e-27 94.6 0.0 9e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 EPS30702.1 - 3.2e-06 27.8 0.0 1.8e-05 25.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPS30702.1 - 2e-05 24.4 0.0 0.013 15.3 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 EPS30702.1 - 2.4e-05 24.2 0.0 3.4e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS30702.1 - 3.6e-05 24.3 0.0 0.0002 22.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPS30702.1 - 0.0024 18.6 0.0 0.0096 16.7 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain N2227 PF07942.12 EPS30702.1 - 0.19 10.9 0.0 0.27 10.4 0.0 1.1 1 0 0 1 1 1 0 N2227-like protein Aegerolysin PF06355.13 EPS30703.1 - 1.5e-41 141.5 0.2 1.8e-41 141.3 0.2 1.0 1 0 0 1 1 1 1 Aegerolysin DUF3425 PF11905.8 EPS30704.1 - 5.4e-20 71.6 0.2 1e-19 70.7 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) LysM PF01476.20 EPS30705.1 - 4e-10 39.6 0.2 7.2e-10 38.8 0.1 1.5 2 0 0 2 2 2 1 LysM domain Aldo_ket_red PF00248.21 EPS30705.1 - 0.028 13.6 0.0 0.037 13.2 0.0 1.0 1 0 0 1 1 1 0 Aldo/keto reductase family NmrA PF05368.13 EPS30706.1 - 3.8e-12 46.3 0.0 6e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPS30706.1 - 1.5e-11 44.6 0.0 2.5e-11 43.8 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EPS30706.1 - 7.8e-06 25.5 0.1 4.1e-05 23.2 0.0 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EPS30706.1 - 8.3e-05 22.6 0.1 0.00015 21.7 0.1 1.5 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.24 EPS30706.1 - 9.5e-05 22.8 0.2 0.00055 20.4 0.1 2.1 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.12 EPS30706.1 - 0.001 18.3 0.0 0.0014 17.9 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 EPS30706.1 - 0.0014 18.1 0.0 0.035 13.5 0.0 2.2 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 EPS30706.1 - 0.0025 17.3 0.1 0.015 14.8 0.1 2.1 2 1 0 2 2 2 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 EPS30706.1 - 0.0032 17.7 0.1 0.0064 16.7 0.1 1.6 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 EPS30706.1 - 0.0078 16.3 0.6 0.11 12.6 0.2 2.3 1 1 1 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.15 EPS30706.1 - 0.011 14.9 0.1 0.018 14.2 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein CbiA PF01656.23 EPS30706.1 - 0.45 10.6 1.4 1.3 9.1 1.4 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Med27 PF11571.8 EPS30709.1 - 2.8e-20 72.5 0.0 5.1e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 27 RuBisCO_large_N PF02788.16 EPS30709.1 - 0.16 12.2 0.0 0.35 11.0 0.0 1.6 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain PqqD PF05402.12 EPS30711.1 - 0.18 12.1 0.1 5.9 7.3 0.0 2.3 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) Apt1 PF10351.9 EPS30711.1 - 1.2 7.9 3.8 1.4 7.7 3.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF4470 PF14737.6 EPS30714.1 - 1.5e-19 69.9 0.1 2.7e-19 69.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 EPS30714.1 - 3.5e-08 33.4 12.4 6.3e-08 32.6 12.4 1.4 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 EPS30714.1 - 1.9 8.4 10.6 3.6 7.5 10.6 1.4 1 0 0 1 1 1 0 HIT zinc finger SNF2_N PF00176.23 EPS30715.1 - 4.9e-68 229.4 0.0 8.8e-68 228.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EPS30715.1 - 3.8e-19 69.1 0.0 1.4e-18 67.2 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPS30715.1 - 3.6e-05 23.8 0.0 0.00011 22.3 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Baculo_PEP_C PF04513.12 EPS30715.1 - 0.095 12.7 0.2 0.22 11.6 0.2 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pkinase PF00069.25 EPS30716.1 - 9.3e-49 166.2 0.1 3.5e-48 164.3 0.1 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS30716.1 - 2.1e-21 76.4 0.0 4e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EPS30716.1 - 0.00068 19.6 0.1 0.0017 18.3 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EPS30716.1 - 0.013 15.1 0.7 0.066 12.8 0.7 2.0 1 1 0 1 1 1 0 RIO1 family Kdo PF06293.14 EPS30716.1 - 0.12 11.7 0.4 0.67 9.3 0.0 2.2 2 1 1 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family MLANA PF14991.6 EPS30716.1 - 0.13 12.5 5.6 0.32 11.3 5.6 1.6 1 0 0 1 1 1 0 Protein melan-A eIF-3c_N PF05470.12 EPS30717.1 - 1.7e-180 601.3 22.4 1.7e-180 601.3 22.4 2.4 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 EPS30717.1 - 1.7e-12 47.8 4.2 3.5e-12 46.8 0.0 3.4 3 2 1 4 4 4 1 PCI domain DUF1385 PF07136.11 EPS30717.1 - 0.018 14.3 0.0 0.038 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1385) DUF4337 PF14235.6 EPS30717.1 - 0.76 9.9 8.3 2.8 8.0 8.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) ADH_zinc_N_2 PF13602.6 EPS30720.1 - 2.1e-21 77.4 0.0 3.2e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EPS30720.1 - 1.4e-18 67.1 0.5 1.8e-17 63.5 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 EPS30720.1 - 0.0084 15.9 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) Epimerase PF01370.21 EPS30720.1 - 0.011 15.2 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ELFV_dehydrog PF00208.21 EPS30720.1 - 0.015 15.0 0.3 0.023 14.4 0.3 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DapB_N PF01113.20 EPS30720.1 - 0.072 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus TerD PF02342.18 EPS30721.1 - 0.04 13.4 0.0 0.051 13.0 0.0 1.1 1 0 0 1 1 1 0 TerD domain IBR PF01485.21 EPS30722.1 - 6.6e-05 23.1 3.2 6.6e-05 23.1 3.2 4.5 4 1 0 4 4 4 2 IBR domain, a half RING-finger domain adh_short PF00106.25 EPS30723.1 - 1.3e-82 276.0 10.9 1.5e-44 151.8 0.7 2.6 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 EPS30723.1 - 3.6e-67 226.3 5.7 7.3e-36 123.9 0.3 2.4 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 EPS30723.1 - 6e-33 113.0 0.0 1.1e-32 112.1 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 EPS30723.1 - 2.8e-28 99.0 3.9 1.8e-13 50.8 0.1 2.4 2 0 0 2 2 2 2 KR domain THF_DHG_CYH_C PF02882.19 EPS30723.1 - 4.9e-05 22.7 0.1 0.0012 18.2 0.2 2.6 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.21 EPS30723.1 - 0.013 14.9 1.0 1 8.7 0.1 2.4 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Ldh_1_N PF00056.23 EPS30723.1 - 0.031 14.3 0.9 11 6.1 0.7 2.9 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EPS30723.1 - 0.72 9.7 4.7 3.7 7.4 0.9 2.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PRK PF00485.18 EPS30724.1 - 0.0099 15.6 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 EPS30724.1 - 0.02 15.3 0.1 0.038 14.4 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain SRP54 PF00448.22 EPS30724.1 - 0.027 14.1 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 EPS30724.1 - 0.033 13.5 0.0 0.08 12.2 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin MeaB PF03308.16 EPS30724.1 - 0.041 12.9 0.0 0.34 9.9 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MobB PF03205.14 EPS30724.1 - 0.093 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SRP_SPB PF02978.19 EPS30724.1 - 0.17 12.5 0.0 0.36 11.5 0.0 1.6 1 0 0 1 1 1 0 Signal peptide binding domain EAP30 PF04157.16 EPS30725.1 - 8.1e-71 238.0 0.1 9.2e-71 237.9 0.1 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family HTH_6 PF01418.17 EPS30725.1 - 0.0026 17.7 0.1 0.025 14.5 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain, rpiR family Peptidase_M50 PF02163.22 EPS30725.1 - 0.026 13.8 0.0 0.035 13.4 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M50 HTH_27 PF13463.6 EPS30725.1 - 0.041 14.4 0.1 0.11 13.0 0.0 1.8 2 0 0 2 2 2 0 Winged helix DNA-binding domain TrmB PF01978.19 EPS30725.1 - 0.055 13.3 0.3 7.7 6.5 0.1 3.0 2 1 1 3 3 3 0 Sugar-specific transcriptional regulator TrmB Ribosomal_L30_N PF08079.12 EPS30726.1 - 2e-28 98.4 16.4 3.6e-28 97.6 16.4 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 EPS30726.1 - 1.4e-17 63.3 1.9 3.4e-17 62.1 1.9 1.7 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e DNA_gyraseB_C PF00986.21 EPS30727.1 - 0.013 15.6 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 DNA gyrase B subunit, carboxyl terminus F-box-like_2 PF13013.6 EPS30728.1 - 0.003 17.5 1.1 1.1 9.3 0.3 2.6 2 1 0 2 2 2 2 F-box-like domain Zn_clus PF00172.18 EPS30729.1 - 1.9e-08 34.3 9.4 3.6e-08 33.4 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EPS30729.1 - 8.4e-06 24.8 0.7 1.2e-05 24.3 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.13 EPS30730.1 - 7.9e-71 237.9 11.8 7.9e-71 237.9 11.8 1.8 1 1 1 2 2 2 1 RTA1 like protein RTA1 PF04479.13 EPS30731.1 - 2.6e-71 239.5 12.2 3.4e-71 239.1 12.2 1.1 1 0 0 1 1 1 1 RTA1 like protein LHC PF00556.20 EPS30731.1 - 1.7 8.9 6.7 3 8.1 0.1 2.7 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit ABA_GPCR PF12430.8 EPS30731.1 - 4.6 7.0 8.9 0.34 10.6 0.8 2.7 2 1 0 2 2 2 0 Abscisic acid G-protein coupled receptor DUF4271 PF14093.6 EPS30732.1 - 0.0072 16.3 2.2 0.0096 15.9 2.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4271) MARVEL PF01284.23 EPS30732.1 - 0.065 13.3 7.5 0.093 12.8 7.5 1.2 1 0 0 1 1 1 0 Membrane-associating domain MENTAL PF10457.9 EPS30732.1 - 0.08 12.7 3.5 0.15 11.9 3.5 1.7 1 1 0 1 1 1 0 Cholesterol-capturing domain DUF2663 PF10864.8 EPS30732.1 - 0.3 11.5 2.6 0.29 11.5 0.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2663) Yip1 PF04893.17 EPS30732.1 - 0.88 9.3 9.8 1.2 8.9 9.8 1.2 1 0 0 1 1 1 0 Yip1 domain DUF3043 PF11241.8 EPS30732.1 - 1.3 9.1 3.3 0.67 10.0 0.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3043) DUF202 PF02656.15 EPS30732.1 - 2.9 8.4 8.2 2.1 8.9 1.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF4282 PF14110.6 EPS30732.1 - 4.4 8.1 11.1 0.94 10.3 4.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) Cys_Met_Meta_PP PF01053.20 EPS30735.1 - 2.7e-142 473.8 0.0 3.1e-142 473.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EPS30735.1 - 3e-06 26.7 0.0 4.6e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EPS30735.1 - 1.8e-05 23.9 0.0 3.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.11 EPS30735.1 - 5.8e-05 21.8 0.0 0.00055 18.6 0.0 2.0 1 1 0 1 1 1 1 Methionine gamma-lyase DegT_DnrJ_EryC1 PF01041.17 EPS30735.1 - 0.0022 17.4 0.1 0.0068 15.8 0.0 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 EPS30735.1 - 0.047 13.0 0.0 0.15 11.3 0.0 1.7 2 0 0 2 2 2 0 Beta-eliminating lyase PigN PF04987.14 EPS30736.1 - 6.2e-166 552.8 34.5 6.2e-166 552.8 34.5 1.5 2 0 0 2 2 2 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 EPS30736.1 - 5.3e-10 39.4 2.1 2e-08 34.3 1.7 2.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EPS30736.1 - 5.9e-09 35.8 0.2 9.5e-09 35.1 0.2 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 EPS30736.1 - 0.0022 17.4 0.0 0.0037 16.7 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily PsaF PF17550.2 EPS30736.1 - 0.016 14.7 1.0 0.78 9.2 0.0 2.8 2 0 0 2 2 2 0 Family of unknown function Csm1 PF12539.8 EPS30737.1 - 5.6e-31 107.0 0.4 1.4e-30 105.7 0.2 1.8 2 0 0 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 AAA_13 PF13166.6 EPS30737.1 - 0.026 13.2 6.0 0.036 12.7 6.0 1.2 1 0 0 1 1 1 0 AAA domain DUF3450 PF11932.8 EPS30737.1 - 0.068 12.5 12.3 0.15 11.4 7.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF5094 PF17015.5 EPS30737.1 - 0.11 12.6 0.1 0.11 12.6 0.1 3.7 3 2 0 3 3 3 0 Domain of unknown function (DUF5094) GAS PF13851.6 EPS30737.1 - 0.14 11.5 10.3 0.079 12.3 3.6 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Spc42p PF11544.8 EPS30737.1 - 0.18 11.8 1.4 0.33 11.0 0.2 2.1 2 0 0 2 2 2 0 Spindle pole body component Spc42p FlxA PF14282.6 EPS30737.1 - 0.26 11.3 11.3 1.5 8.9 11.3 2.4 1 0 0 1 1 1 0 FlxA-like protein ADIP PF11559.8 EPS30737.1 - 0.54 10.3 14.2 1 9.4 12.8 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding USP8_interact PF08941.10 EPS30737.1 - 0.6 9.9 3.8 0.2 11.5 0.3 1.9 2 0 0 2 2 2 0 USP8 interacting DUF3138 PF11336.8 EPS30737.1 - 0.63 8.6 6.2 1.2 7.7 6.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) COG2 PF06148.11 EPS30737.1 - 0.67 10.1 5.7 2.9 8.0 5.1 2.2 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Pep1_7 PF17232.2 EPS30737.1 - 1 9.9 4.1 8.8 6.9 0.3 3.0 2 0 0 2 2 2 0 Elicitor peptide 1-7 KxDL PF10241.9 EPS30737.1 - 1.1 9.6 7.0 2.4 8.5 3.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein SKA2 PF16740.5 EPS30737.1 - 1.7 8.5 10.8 1.7 8.5 3.8 3.1 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 2 Spc7 PF08317.11 EPS30737.1 - 3.3 6.5 13.8 5.5 5.8 13.1 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF4200 PF13863.6 EPS30737.1 - 3.4 8.1 10.2 36 4.8 10.2 2.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) APG6_N PF17675.1 EPS30737.1 - 5.8 7.5 17.4 0.53 10.8 12.1 2.0 2 0 0 2 2 1 0 Apg6 coiled-coil region AAA PF00004.29 EPS30738.1 - 2.8e-37 128.1 0.0 7.3e-37 126.8 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EPS30738.1 - 2.3e-07 30.5 0.0 5.6e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EPS30738.1 - 3e-05 24.5 0.3 0.00088 19.7 0.1 2.6 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EPS30738.1 - 3.1e-05 23.8 0.0 7e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 EPS30738.1 - 3.6e-05 23.8 0.0 8.6e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EPS30738.1 - 8.7e-05 22.5 0.2 0.001 19.1 0.2 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EPS30738.1 - 0.00013 22.2 0.0 0.00033 20.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 EPS30738.1 - 0.00014 22.4 0.0 0.0005 20.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EPS30738.1 - 0.00035 20.9 0.1 0.011 15.9 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 EPS30738.1 - 0.00039 20.6 0.0 0.00084 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EPS30738.1 - 0.00084 18.8 0.1 0.0016 17.9 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EPS30738.1 - 0.0012 19.2 0.0 0.0033 17.8 0.0 1.9 1 1 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 EPS30738.1 - 0.0013 18.5 0.0 0.0031 17.3 0.0 1.6 2 0 0 2 2 1 1 IstB-like ATP binding protein TniB PF05621.11 EPS30738.1 - 0.0016 17.9 0.0 1.7 8.0 0.0 2.6 2 1 1 3 3 3 2 Bacterial TniB protein AAA_25 PF13481.6 EPS30738.1 - 0.0026 17.4 0.1 0.048 13.2 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EPS30738.1 - 0.0054 17.0 0.0 0.016 15.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain NACHT PF05729.12 EPS30738.1 - 0.0054 16.7 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_24 PF13479.6 EPS30738.1 - 0.01 15.6 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 EPS30738.1 - 0.023 14.8 0.0 0.052 13.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 EPS30738.1 - 0.024 13.7 0.0 0.04 13.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Guanylate_kin PF00625.21 EPS30738.1 - 0.026 14.2 0.0 1.8 8.2 0.0 3.2 3 1 0 4 4 4 0 Guanylate kinase Sigma54_activat PF00158.26 EPS30738.1 - 0.031 14.0 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Rad17 PF03215.15 EPS30738.1 - 0.032 14.2 0.1 0.088 12.7 0.1 1.6 1 1 1 2 2 2 0 Rad17 P-loop domain ABC_tran PF00005.27 EPS30738.1 - 0.042 14.4 0.0 0.12 12.9 0.0 1.8 1 1 0 1 1 1 0 ABC transporter ATPase_2 PF01637.18 EPS30738.1 - 0.047 13.6 0.0 0.2 11.6 0.0 1.9 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 EPS30738.1 - 0.05 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region CPT PF07931.12 EPS30738.1 - 0.063 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein DUF815 PF05673.13 EPS30738.1 - 0.064 12.4 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TsaE PF02367.17 EPS30738.1 - 0.1 12.6 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE COesterase PF00135.28 EPS30740.1 - 3.5e-82 276.9 0.0 1.8e-81 274.5 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EPS30740.1 - 2.1e-05 24.5 0.0 0.00014 21.8 0.0 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EPS30740.1 - 0.00084 18.9 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family tRNA_SAD PF07973.14 EPS30741.1 - 2.3e-06 27.6 1.0 3.7e-06 26.9 1.0 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 EPS30741.1 - 7.2e-05 21.5 0.0 0.0001 21.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) FKBP_C PF00254.28 EPS30742.1 - 6.3e-26 90.5 0.0 7.4e-26 90.3 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PHP PF02811.19 EPS30743.1 - 5.3e-14 52.9 0.0 9e-14 52.1 0.0 1.4 1 1 0 1 1 1 1 PHP domain ACPS PF01648.20 EPS30744.1 - 7.6e-12 45.4 0.0 4.3e-11 43.0 0.0 1.9 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 EPS30744.1 - 0.036 14.2 0.1 7.3 6.8 0.1 2.4 2 0 0 2 2 2 0 4'-phosphopantetheinyl transferase N-terminal domain ATP19 PF11022.8 EPS30745.1 - 4.2e-26 91.1 0.2 4.7e-26 90.9 0.2 1.0 1 0 0 1 1 1 1 ATP synthase subunit K MTP18 PF10558.9 EPS30746.1 - 5.2e-82 273.9 0.0 7.6e-82 273.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) EAP30 PF04157.16 EPS30751.1 - 4.4e-43 147.3 0.4 5.7e-43 146.9 0.4 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36-NZF-N PF16988.5 EPS30751.1 - 2.8e-24 84.3 3.0 2.8e-24 84.3 3.0 2.9 3 1 0 3 3 3 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain Vps36_ESCRT-II PF11605.8 EPS30751.1 - 4.9e-24 84.3 0.0 8.1e-24 83.6 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-Sec23_Sec24 PF04810.15 EPS30751.1 - 0.0004 20.4 5.7 0.0052 16.8 0.6 2.4 2 0 0 2 2 2 2 Sec23/Sec24 zinc finger zf-RanBP PF00641.18 EPS30751.1 - 0.0044 16.3 1.2 0.0044 16.3 1.2 2.7 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others GRAM PF02893.20 EPS30751.1 - 0.0045 16.9 0.0 0.0088 15.9 0.0 1.4 1 0 0 1 1 1 1 GRAM domain DUF3646 PF12362.8 EPS30751.1 - 0.093 13.1 0.1 0.53 10.6 0.1 2.2 2 0 0 2 2 2 0 DNA polymerase III gamma and tau subunits C terminal zf-C2H2_4 PF13894.6 EPS30751.1 - 0.3 12.0 5.5 21 6.3 0.0 3.5 2 1 1 3 3 3 0 C2H2-type zinc finger DZR PF12773.7 EPS30751.1 - 0.3 11.1 5.0 0.42 10.7 0.4 2.4 2 0 0 2 2 2 0 Double zinc ribbon RecR PF02132.15 EPS30751.1 - 2 8.1 3.9 5.5 6.7 0.9 2.6 2 0 0 2 2 2 0 RecR protein SAC3_GANP PF03399.16 EPS30752.1 - 2.4e-25 89.5 1.2 3e-23 82.6 1.2 2.1 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 EPS30752.1 - 2.6e-05 24.2 0.6 0.00016 21.7 0.1 2.1 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family Agouti PF05039.12 EPS30752.1 - 0.34 11.6 1.2 1.5 9.6 0.1 2.5 3 0 0 3 3 3 0 Agouti protein SH3_1 PF00018.28 EPS30754.1 - 6.2e-25 86.6 0.0 4.1e-11 42.3 0.0 2.8 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.6 EPS30754.1 - 4.3e-14 52.1 0.1 2.4e-06 27.3 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.24 EPS30754.1 - 5.1e-13 49.0 0.0 1e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 PX domain PB1 PF00564.24 EPS30754.1 - 4.4e-09 36.2 0.2 1e-08 35.0 0.2 1.6 1 0 0 1 1 1 1 PB1 domain SH3_2 PF07653.17 EPS30754.1 - 5.3e-09 35.6 0.0 1.7e-05 24.4 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain GH97_C PF14509.6 EPS30754.1 - 0.095 12.9 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation AFG1_ATPase PF03969.16 EPS30755.1 - 5.7e-93 311.7 0.0 2.9e-88 296.2 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 EPS30755.1 - 0.00016 22.1 0.2 0.79 10.1 0.0 3.3 2 1 0 3 3 3 2 AAA ATPase domain AAA_14 PF13173.6 EPS30755.1 - 0.0056 16.7 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EPS30755.1 - 0.015 15.6 0.0 0.077 13.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA PF00004.29 EPS30755.1 - 0.017 15.6 0.0 0.049 14.1 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.18 EPS30755.1 - 0.041 13.7 0.1 2.4 7.9 0.0 2.4 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_5 PF07728.14 EPS30755.1 - 0.049 13.6 0.0 0.094 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EPS30755.1 - 0.065 13.6 0.0 0.23 11.9 0.0 2.0 2 0 0 2 2 2 0 RNA helicase Catalase PF00199.19 EPS30756.1 - 3e-168 559.8 0.1 3.9e-168 559.5 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EPS30756.1 - 1.1e-17 64.0 0.2 2.8e-17 62.7 0.2 1.8 2 0 0 2 2 2 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.24 EPS30756.1 - 6.4e-10 39.1 0.1 1.1e-09 38.3 0.1 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Catalase_C PF18011.1 EPS30756.1 - 2e-08 34.0 1.0 4.4e-08 32.9 1.0 1.6 1 0 0 1 1 1 1 C-terminal domain found in long catalases Potyvirid-P3 PF13608.6 EPS30756.1 - 0.083 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein Amidase PF01425.21 EPS30757.1 - 5.9e-100 335.4 0.0 9.8e-100 334.6 0.0 1.3 1 1 0 1 1 1 1 Amidase Chitin_synth_1 PF01644.17 EPS30758.1 - 2.1e-78 261.9 0.1 3.1e-78 261.4 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EPS30758.1 - 9.1e-27 92.8 0.3 2.1e-26 91.7 0.3 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EPS30758.1 - 9.5e-22 77.3 4.7 2.3e-19 69.4 0.0 2.5 2 1 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EPS30758.1 - 1.4e-05 25.1 0.5 1.4e-05 25.1 0.5 2.0 2 1 0 2 2 2 1 Glycosyl transferase family group 2 DUF1774 PF08611.10 EPS30759.1 - 9.8e-36 122.0 2.2 9.8e-36 122.0 2.2 2.2 2 1 0 2 2 2 1 Fungal protein of unknown function (DUF1774) Inositol_P PF00459.25 EPS30760.1 - 7e-37 127.4 0.3 2.1e-36 125.8 0.3 1.6 1 1 0 1 1 1 1 Inositol monophosphatase family DUF2264 PF10022.9 EPS30761.1 - 2.4e-144 480.8 0.2 5.9e-144 479.5 0.1 1.6 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2264) Cofilin_ADF PF00241.20 EPS30762.1 - 3.9e-21 75.1 0.1 4.3e-21 74.9 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein zf-AN1 PF01428.16 EPS30763.1 - 1.7e-23 82.5 25.6 8e-12 45.1 10.4 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger zf-C5HC2 PF02928.16 EPS30763.1 - 0.00011 22.5 7.7 0.1 13.0 1.4 2.5 2 0 0 2 2 2 2 C5HC2 zinc finger Transp_Tc5_C PF04236.15 EPS30763.1 - 0.012 15.9 12.6 0.084 13.2 4.6 2.3 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain zf-RING_5 PF14634.6 EPS30763.1 - 0.049 13.6 0.5 0.049 13.6 0.5 2.6 3 0 0 3 3 3 0 zinc-RING finger domain IBR PF01485.21 EPS30763.1 - 0.15 12.3 21.5 0.56 10.5 7.8 2.8 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain C1_4 PF07975.12 EPS30763.1 - 0.3 11.4 17.9 1.4 9.2 7.6 3.0 2 2 0 2 2 2 0 TFIIH C1-like domain Zn-ribbon_8 PF09723.10 EPS30763.1 - 1.5 9.0 11.2 1 9.6 3.0 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_5 PF13719.6 EPS30763.1 - 2.7 7.8 6.3 2.6 7.9 1.0 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Tmemb_55A PF09788.9 EPS30763.1 - 5.2 6.1 10.7 5.5 6.0 1.6 2.2 2 0 0 2 2 2 0 Transmembrane protein 55A zf-LITAF-like PF10601.9 EPS30763.1 - 6.9 7.0 11.6 9.1 6.6 0.8 2.4 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain Thymidylat_synt PF00303.19 EPS30764.1 - 1.5e-104 348.8 0.0 1.8e-104 348.7 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase TGT PF01702.18 EPS30765.1 - 7.3e-147 489.1 0.0 8.6e-147 488.9 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase MFS_1 PF07690.16 EPS30766.1 - 2.6e-28 99.0 30.1 3.5e-28 98.5 30.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily CRA PF06589.11 EPS30767.1 - 0.0046 17.0 0.5 0.0065 16.6 0.5 1.2 1 0 0 1 1 1 1 Circumsporozoite-related antigen (CRA) DUF1492 PF07374.11 EPS30767.1 - 0.0088 16.2 0.0 0.0096 16.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1492) SAC3 PF12209.8 EPS30767.1 - 0.018 15.2 0.3 0.023 14.8 0.3 1.2 1 0 0 1 1 1 0 Leucine permease transcriptional regulator helical domain dsrm PF00035.26 EPS30769.1 - 0.00094 19.9 0.1 0.002 18.8 0.1 1.6 1 1 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.7 EPS30769.1 - 0.0011 19.2 0.2 0.0086 16.3 0.2 2.0 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 RPA_interact_N PF14766.6 EPS30769.1 - 0.11 12.1 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 Replication protein A interacting N-terminal dsRBD2 PF17842.1 EPS30769.1 - 0.14 12.3 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 R3H-assoc PF13902.6 EPS30774.1 - 8e-22 78.1 7.0 8e-22 78.1 7.0 2.4 2 1 0 2 2 2 1 R3H-associated N-terminal domain R3H PF01424.22 EPS30774.1 - 0.0029 17.6 0.4 0.049 13.6 0.1 2.7 2 1 0 2 2 2 1 R3H domain Peptidase_M28 PF04389.17 EPS30775.1 - 1.1e-28 100.3 0.1 1.9e-28 99.5 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EPS30775.1 - 1.1e-05 25.3 0.0 2.1e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Ala_racemase_N PF01168.20 EPS30776.1 - 4.2e-27 95.2 0.1 5.2e-27 94.9 0.1 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.6 EPS30776.1 - 1.1e-21 77.3 0.0 3.2e-21 75.8 0.0 1.9 2 0 0 2 2 2 1 Putative serine dehydratase domain SDH_alpha PF03313.15 EPS30776.1 - 0.00067 19.4 0.4 0.0067 16.1 0.0 2.3 2 0 0 2 2 2 1 Serine dehydratase alpha chain GTP_CH_N PF12471.8 EPS30776.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 GTP cyclohydrolase N terminal Pribosyltran PF00156.27 EPS30778.1 - 6.5e-06 25.7 0.0 1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain PTRF_SDPR PF15237.6 EPS30778.1 - 0.13 11.8 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 PTRF/SDPR family DPM3 PF08285.11 EPS30779.1 - 1.3e-33 115.1 0.1 1.4e-33 114.9 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Phage_holin_3_6 PF07332.11 EPS30779.1 - 0.18 11.9 2.3 0.98 9.5 2.4 1.8 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III KAP PF05804.12 EPS30780.1 - 0.002 16.4 0.2 0.037 12.2 0.0 2.1 2 0 0 2 2 2 2 Kinesin-associated protein (KAP) 3HCDH_N PF02737.18 EPS30781.1 - 1.2e-52 178.4 0.9 1.7e-52 177.9 0.9 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EPS30781.1 - 1.8e-33 115.0 0.1 5.3e-33 113.5 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EPS30781.1 - 3.7e-06 27.2 0.1 9.4e-06 25.9 0.1 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 EPS30781.1 - 0.00025 21.3 0.1 0.00044 20.5 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DAO PF01266.24 EPS30781.1 - 0.0047 16.6 0.0 0.0067 16.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPS30781.1 - 0.011 15.0 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 EPS30781.1 - 0.015 14.7 0.4 0.052 12.9 0.1 1.9 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EPS30781.1 - 0.019 14.5 0.1 0.038 13.6 0.1 1.5 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TIMELESS PF04821.14 EPS30782.1 - 4.9e-88 295.0 0.3 4.9e-88 295.0 0.3 2.3 3 0 0 3 3 3 1 Timeless protein TIMELESS_C PF05029.13 EPS30782.1 - 1.4e-54 186.3 30.4 2.9e-53 181.9 0.5 4.2 2 1 1 3 3 3 2 Timeless protein C terminal region PhzC-PhzF PF02567.16 EPS30783.1 - 1.2e-39 136.5 0.1 1.5e-39 136.1 0.1 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein DUF1857 PF08982.11 EPS30784.1 - 2.1e-46 157.4 0.0 2.4e-46 157.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) Acetyltransf_7 PF13508.7 EPS30785.1 - 6.9e-06 26.4 0.0 1.1e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPS30785.1 - 4.1e-05 23.8 0.0 5.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EPS30785.1 - 0.00085 19.3 0.0 0.0013 18.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPS30785.1 - 0.052 13.5 0.0 0.11 12.4 0.0 1.5 1 1 0 1 1 1 0 FR47-like protein DUF1180 PF06679.12 EPS30786.1 - 4.8 7.6 7.7 7.9 6.9 7.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Zn_clus PF00172.18 EPS30788.1 - 7.9e-09 35.5 13.1 7.9e-09 35.5 13.1 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S64 PF08192.11 EPS30788.1 - 0.15 10.6 0.0 0.25 9.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S64 Homeodomain PF00046.29 EPS30789.1 - 8.6e-17 60.7 4.1 2.5e-16 59.3 4.1 1.8 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EPS30789.1 - 0.1 12.5 0.2 0.24 11.3 0.2 1.6 1 0 0 1 1 1 0 Homeobox KN domain efThoc1 PF11957.8 EPS30792.1 - 3.4e-149 497.7 0.0 4.3e-149 497.3 0.0 1.1 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Wap1 PF16997.5 EPS30792.1 - 0.13 11.4 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Wap1 domain Aquarius_N PF16399.5 EPS30793.1 - 0 1090.1 0.0 0 1089.8 0.0 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 EPS30793.1 - 1.3e-25 90.2 0.0 2.4e-25 89.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EPS30793.1 - 3.3e-22 79.5 0.0 9.1e-22 78.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EPS30793.1 - 3.6e-07 30.4 0.0 8.5e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EPS30793.1 - 1e-06 28.6 0.0 0.0004 20.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EPS30793.1 - 2.3e-06 28.0 0.0 5.1e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EPS30793.1 - 0.00014 21.7 0.0 0.11 12.2 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA PF00004.29 EPS30793.1 - 0.00044 20.7 0.0 0.0018 18.7 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.15 EPS30793.1 - 0.0006 19.2 0.1 0.025 13.9 0.0 2.7 3 0 0 3 3 3 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 EPS30793.1 - 0.005 17.2 0.0 0.031 14.7 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain DEAD PF00270.29 EPS30793.1 - 0.0055 16.5 0.0 0.028 14.2 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase UvrD_C_2 PF13538.6 EPS30793.1 - 0.0086 15.9 0.9 0.037 13.9 0.5 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.6 EPS30793.1 - 0.012 15.9 0.0 0.053 13.8 0.0 2.1 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EPS30793.1 - 0.035 13.3 1.0 0.069 12.4 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 EPS30793.1 - 0.048 13.6 0.0 0.096 12.6 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea SMC_N PF02463.19 EPS30793.1 - 0.049 13.1 0.0 0.074 12.5 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_5 PF07728.14 EPS30793.1 - 0.052 13.6 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) UvrD-helicase PF00580.21 EPS30793.1 - 0.067 12.7 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain RuvB_N PF05496.12 EPS30793.1 - 0.12 12.2 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_25 PF13481.6 EPS30793.1 - 0.13 11.9 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Adeno_IVa2 PF02456.15 EPS30793.1 - 0.15 10.8 0.0 0.29 9.9 0.0 1.4 1 0 0 1 1 1 0 Adenovirus IVa2 protein 4HBT PF03061.22 EPS30794.1 - 4.6e-13 49.3 0.1 6.6e-13 48.8 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 EPS30794.1 - 0.035 14.2 0.0 0.049 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) Tfb2 PF03849.14 EPS30795.1 - 2.1e-136 454.6 0.0 3.5e-136 453.8 0.0 1.3 2 0 0 2 2 2 1 Transcription factor Tfb2 Tfb2_C PF18307.1 EPS30795.1 - 9.3e-24 83.6 0.8 1.9e-23 82.7 0.8 1.6 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 EPS30795.1 - 5e-06 26.7 0.0 0.00012 22.2 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4006 PF13179.6 EPS30796.1 - 0.067 13.1 1.6 0.07 13.0 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF4006) DUF3431 PF11913.8 EPS30797.1 - 2.8e-69 233.2 0.1 3.6e-69 232.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Adaptin_N PF01602.20 EPS30799.1 - 9.6e-126 420.4 3.3 1.4e-125 419.9 3.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 EPS30799.1 - 5.1e-44 149.1 0.0 1.1e-43 147.9 0.0 1.6 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 EPS30799.1 - 4.8e-16 59.0 0.0 1.2e-15 57.8 0.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain RTP1_C1 PF10363.9 EPS30799.1 - 0.063 13.5 0.3 0.48 10.6 0.1 2.6 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Ala_racemase_N PF01168.20 EPS30800.1 - 1.4e-23 83.7 0.0 2.3e-23 83.0 0.0 1.3 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain Hist_deacetyl PF00850.19 EPS30803.1 - 8.7e-52 176.5 0.0 1.4e-51 175.8 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain RTP801_C PF07809.11 EPS30803.1 - 0.0073 16.2 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 RTP801 C-terminal region MTP18 PF10558.9 EPS30804.1 - 0.2 11.6 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial 18 KDa protein (MTP18) SLAC1 PF03595.17 EPS30805.1 - 3.6e-78 263.1 48.9 4.2e-78 262.9 48.9 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel CaKB PF03185.15 EPS30805.1 - 0.043 13.5 0.9 0.043 13.5 0.9 1.9 3 0 0 3 3 3 0 Calcium-activated potassium channel, beta subunit APH PF01636.23 EPS30806.1 - 2.4e-22 80.1 0.0 3.2e-10 40.3 0.0 2.9 2 1 0 2 2 2 2 Phosphotransferase enzyme family zf-AN1 PF01428.16 EPS30806.1 - 6.6e-07 29.4 29.4 0.0014 18.8 8.3 2.4 2 0 0 2 2 2 2 AN1-like Zinc finger Haspin_kinase PF12330.8 EPS30806.1 - 0.013 14.5 0.0 1.2 8.0 0.0 2.4 2 0 0 2 2 2 0 Haspin like kinase domain Transp_Tc5_C PF04236.15 EPS30806.1 - 0.33 11.3 22.1 0.53 10.7 4.4 2.6 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain DUF3435 PF11917.8 EPS30807.1 - 4.6e-14 52.2 1.9 4.9e-14 52.1 1.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) DUF812 PF05667.11 EPS30807.1 - 0.0059 15.6 1.1 0.0065 15.4 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) RRF PF01765.19 EPS30807.1 - 0.045 13.7 1.5 0.053 13.5 1.5 1.1 1 0 0 1 1 1 0 Ribosome recycling factor DUF3435 PF11917.8 EPS30808.1 - 1.5e-09 37.3 0.1 1.6e-09 37.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) adh_short PF00106.25 EPS30809.1 - 1.5e-44 151.8 0.1 2e-44 151.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS30809.1 - 7.3e-30 104.2 0.0 9e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 EPS30809.1 - 1.5e-05 24.5 0.0 0.00012 21.6 0.0 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.13 EPS30809.1 - 0.00014 21.5 0.3 0.0024 17.4 0.1 2.1 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.6 EPS30809.1 - 0.0053 16.7 0.0 0.0088 16.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EPS30809.1 - 0.026 14.0 0.0 0.042 13.3 0.0 1.4 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family HAUS2 PF15003.6 EPS30809.1 - 0.18 11.5 0.0 0.33 10.7 0.0 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 ATP-grasp_2 PF08442.10 EPS30810.1 - 2.2e-76 255.9 0.8 2.2e-76 255.9 0.8 1.7 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 EPS30810.1 - 2.8e-25 88.9 0.3 6.3e-25 87.8 0.3 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 EPS30810.1 - 1.8e-06 27.6 0.8 3.5e-06 26.6 0.3 1.7 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 EPS30810.1 - 0.00021 21.1 2.2 0.0058 16.4 0.3 2.9 2 1 1 3 3 3 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain VID27_N PF17748.1 EPS30810.1 - 0.053 13.4 0.6 0.11 12.3 0.6 1.5 1 0 0 1 1 1 0 VID27 N-terminal region Succ_CoA_lig PF13607.6 EPS30810.1 - 0.11 12.3 0.2 18 5.1 0.0 2.6 1 1 1 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain F-box PF00646.33 EPS30811.1 - 1.2e-07 31.4 2.1 3.2e-07 30.0 2.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EPS30811.1 - 7.1e-05 22.6 1.3 0.00017 21.4 1.3 1.6 1 0 0 1 1 1 1 F-box-like Med3 PF11593.8 EPS30811.1 - 0.0028 16.9 4.0 0.0042 16.3 4.0 1.2 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal DUF5421 PF17458.2 EPS30811.1 - 0.0032 16.9 1.9 0.0044 16.4 1.9 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5421) Spt20 PF12090.8 EPS30811.1 - 0.016 14.9 9.1 0.024 14.2 9.1 1.2 1 0 0 1 1 1 0 Spt20 family CIAPIN1 PF05093.13 EPS30811.1 - 0.074 13.6 0.2 0.16 12.5 0.2 1.5 1 0 0 1 1 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis CBP_BcsF PF11120.8 EPS30811.1 - 0.097 12.8 0.6 0.2 11.8 0.6 1.5 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsF Transposase_22 PF02994.14 EPS30811.1 - 0.14 12.3 0.4 0.34 11.1 0.4 1.6 1 0 0 1 1 1 0 L1 transposable element RBD-like domain TFIIA PF03153.13 EPS30811.1 - 1.2 9.1 12.9 0.04 13.9 6.8 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Androgen_recep PF02166.16 EPS30811.1 - 1.4 7.7 7.7 2.1 7.1 7.7 1.2 1 0 0 1 1 1 0 Androgen receptor HSF_DNA-bind PF00447.17 EPS30812.1 - 1.9e-29 102.1 0.4 3.2e-29 101.4 0.4 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding DUF3245 PF11595.8 EPS30813.1 - 1.2e-48 165.3 8.6 1.2e-48 165.3 8.6 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF3245) Vps51 PF08700.11 EPS30813.1 - 0.077 13.1 0.3 0.2 11.7 0.1 2.0 2 1 0 2 2 2 0 Vps51/Vps67 Myc_N PF01056.18 EPS30813.1 - 0.31 10.9 4.8 0.081 12.8 0.8 1.8 1 1 0 2 2 2 0 Myc amino-terminal region Helicase_C PF00271.31 EPS30814.1 - 2e-12 47.4 0.0 1.5e-11 44.6 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HA2 PF04408.23 EPS30814.1 - 1.8e-09 37.8 0.0 4.1e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) DEAD PF00270.29 EPS30814.1 - 3.3e-08 33.5 0.0 7.2e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.16 EPS30814.1 - 0.02 15.2 0.0 0.058 13.8 0.0 1.9 1 0 0 1 1 1 0 Oligonucleotide/oligosaccharide-binding (OB)-fold Oxidored-like PF09791.9 EPS30815.1 - 2.1e-23 81.7 3.9 4.1e-23 80.8 3.9 1.5 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DUF5522 PF17653.1 EPS30815.1 - 0.037 14.0 2.3 0.079 12.9 2.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5522) Actin PF00022.19 EPS30817.1 - 2.4e-105 352.5 0.0 1.3e-104 350.1 0.0 1.8 1 1 0 1 1 1 1 Actin GCIP PF13324.6 EPS30819.1 - 1e-23 84.3 4.5 2.4e-23 83.1 4.5 1.6 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting PEX11 PF05648.14 EPS30819.1 - 0.0072 15.8 0.1 0.086 12.3 0.0 2.4 2 0 0 2 2 2 1 Peroxisomal biogenesis factor 11 (PEX11) OHCU_decarbox PF09349.10 EPS30819.1 - 0.11 12.9 0.0 0.36 11.3 0.0 1.8 1 0 0 1 1 1 0 OHCU decarboxylase DUF4611 PF15387.6 EPS30819.1 - 0.12 12.6 10.7 0.35 11.1 2.5 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4611) Med11 PF10280.9 EPS30819.1 - 4.2 7.8 7.4 6 7.3 0.8 3.5 3 1 1 4 4 4 0 Mediator complex protein LRR_8 PF13855.6 EPS30820.1 - 3.8e-28 97.0 40.2 5.1e-09 35.8 0.8 8.6 6 1 0 8 8 8 7 Leucine rich repeat LRR_4 PF12799.7 EPS30820.1 - 3e-26 91.0 50.3 0.00047 20.5 1.7 10.8 5 4 5 11 11 11 11 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EPS30820.1 - 6.1e-05 22.6 18.0 0.07 12.6 0.5 5.2 2 2 3 5 5 5 4 Leucine-rich repeat LRR_1 PF00560.33 EPS30820.1 - 9.1e-05 22.5 46.2 2.5 9.0 0.1 12.4 12 3 0 12 12 12 4 Leucine Rich Repeat Importin_rep_2 PF18786.1 EPS30820.1 - 0.022 14.6 0.4 3.2 7.7 0.0 3.2 2 0 0 2 2 2 0 Importin 13 repeat LRR_6 PF13516.6 EPS30820.1 - 3.3 8.0 43.4 10 6.4 0.4 11.6 13 0 0 13 13 13 0 Leucine Rich repeat TFIIA PF03153.13 EPS30820.1 - 7.7 6.4 11.4 12 5.8 11.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3984 PF13136.6 EPS30821.1 - 0.0065 15.9 4.8 0.0065 15.9 4.8 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3984) YqbF PF14553.6 EPS30821.1 - 0.23 11.3 0.1 0.5 10.3 0.1 1.5 1 0 0 1 1 1 0 YqbF, hypothetical protein domain Ribosomal_L13e PF01294.18 EPS30822.1 - 9e-77 257.0 5.3 9e-77 257.0 5.3 1.3 2 0 0 2 2 2 1 Ribosomal protein L13e Vasohibin PF14822.6 EPS30824.1 - 0.11 11.6 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Vasohibin zf-C2H2 PF00096.26 EPS30825.1 - 0.028 14.9 0.7 7.1 7.3 0.2 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2HC_2 PF13913.6 EPS30825.1 - 0.095 12.6 1.6 0.25 11.3 1.6 1.8 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.6 EPS30825.1 - 8.5 7.5 6.6 7.3 7.7 0.1 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger ABC1 PF03109.16 EPS30828.1 - 3.1e-19 69.3 0.0 2e-09 37.6 0.0 2.9 3 0 0 3 3 3 2 ABC1 family Raf1_HTH PF18579.1 EPS30828.1 - 0.0016 18.1 0.0 0.0033 17.1 0.0 1.5 1 0 0 1 1 1 1 Rubisco accumulation factor 1 helix turn helix domain POTRA_TamA_1 PF17243.2 EPS30828.1 - 0.021 14.9 0.0 0.11 12.7 0.0 2.1 2 0 0 2 2 2 0 POTRA domain TamA domain 1 RIO1 PF01163.22 EPS30828.1 - 0.062 12.9 0.0 0.32 10.6 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Cyto_heme_lyase PF01265.17 EPS30829.1 - 1.1e-129 432.2 1.3 1.3e-129 432.0 1.3 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Fungal_trans_2 PF11951.8 EPS30831.1 - 1.6e-13 50.3 0.2 2.3e-13 49.7 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tricorn_C1 PF14684.6 EPS30831.1 - 0.047 13.8 1.4 0.11 12.6 1.4 1.6 1 0 0 1 1 1 0 Tricorn protease C1 domain SBF2 PF12335.8 EPS30831.1 - 0.094 12.3 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Myotubularin protein cwf18 PF08315.12 EPS30831.1 - 0.23 12.1 4.0 0.42 11.3 4.0 1.3 1 0 0 1 1 1 0 cwf18 pre-mRNA splicing factor UQ_con PF00179.26 EPS30832.1 - 1.1e-19 70.5 0.1 1.6e-19 69.9 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Bac_surface_Ag PF01103.23 EPS30833.1 - 2.5e-41 142.2 0.0 3.1e-41 141.9 0.0 1.1 1 0 0 1 1 1 1 Surface antigen Yip1 PF04893.17 EPS30834.1 - 0.00027 20.7 23.4 0.0052 16.5 23.4 2.4 1 1 0 1 1 1 1 Yip1 domain UFD1 PF03152.14 EPS30835.1 - 1.5e-26 92.9 0.0 7.4e-15 54.8 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin fusion degradation protein UFD1 AZUL PF16558.5 EPS30835.1 - 1.5e-06 28.3 0.1 4.5e-06 26.8 0.1 1.8 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A TF_Zn_Ribbon PF08271.12 EPS30835.1 - 1.5 8.4 0.0 1.5 8.4 0.0 2.9 3 1 0 3 3 3 0 TFIIB zinc-binding IMUP PF15761.5 EPS30836.1 - 0.011 16.4 1.8 0.025 15.2 1.8 1.6 1 0 0 1 1 1 0 Immortalisation up-regulated protein F-box-like PF12937.7 EPS30836.1 - 0.031 14.2 0.0 0.081 12.8 0.0 1.7 1 0 0 1 1 1 0 F-box-like AAA PF00004.29 EPS30838.1 - 2.9e-43 147.5 0.0 4.8e-43 146.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EPS30838.1 - 4.3e-14 52.0 0.0 1e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EPS30838.1 - 1.9e-07 31.2 0.0 5.1e-07 29.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EPS30838.1 - 2.6e-07 30.9 0.0 4.9e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EPS30838.1 - 1.6e-06 28.6 0.0 8.1e-05 23.1 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain Prot_ATP_ID_OB PF16450.5 EPS30838.1 - 8.4e-06 25.7 2.0 2e-05 24.5 2.0 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 EPS30838.1 - 2.2e-05 24.7 0.2 0.0081 16.4 0.0 2.4 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 EPS30838.1 - 0.0001 22.1 0.0 0.0002 21.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EPS30838.1 - 0.00026 21.5 0.0 0.019 15.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 EPS30838.1 - 0.0013 18.0 0.0 0.0026 17.0 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 EPS30838.1 - 0.0016 18.6 0.0 0.0031 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EPS30838.1 - 0.0026 17.5 0.0 0.0046 16.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 EPS30838.1 - 0.0054 16.6 0.0 0.015 15.2 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 EPS30838.1 - 0.0066 15.8 0.0 0.02 14.3 0.0 1.7 2 0 0 2 2 2 1 KaiC Mg_chelatase PF01078.21 EPS30838.1 - 0.0068 15.8 0.1 0.018 14.4 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EPS30838.1 - 0.011 16.0 0.0 0.019 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EPS30838.1 - 0.016 15.2 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 EPS30838.1 - 0.023 13.8 0.0 0.041 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.26 EPS30838.1 - 0.025 14.3 0.0 0.11 12.2 0.0 2.0 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_24 PF13479.6 EPS30838.1 - 0.031 14.0 0.0 0.079 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EPS30838.1 - 0.032 13.7 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 EPS30838.1 - 0.032 13.7 0.0 0.14 11.6 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein HR1 PF02185.16 EPS30838.1 - 0.037 14.1 0.8 0.095 12.8 0.8 1.7 1 0 0 1 1 1 0 Hr1 repeat Prot_ATP_OB_N PF17758.1 EPS30838.1 - 0.04 13.6 0.3 0.14 11.8 0.1 2.1 2 0 0 2 2 1 0 Proteasomal ATPase OB N-terminal domain RNA_helicase PF00910.22 EPS30838.1 - 0.042 14.3 0.0 0.079 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.6 EPS30838.1 - 0.047 13.7 0.0 0.079 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EPS30838.1 - 0.054 13.1 0.0 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 EPS30838.1 - 0.062 12.4 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF2072 PF09845.9 EPS30838.1 - 0.078 13.2 0.1 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein Zeta_toxin PF06414.12 EPS30838.1 - 0.1 11.9 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.6 EPS30838.1 - 0.15 12.4 0.0 0.61 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Na_Ca_ex PF01699.24 EPS30839.1 - 1.2e-22 80.5 26.0 3.5e-15 56.3 13.3 3.9 5 0 0 5 5 5 2 Sodium/calcium exchanger protein YccF PF03733.13 EPS30839.1 - 8.7e-15 55.2 7.5 8.7e-15 55.2 7.5 4.4 5 0 0 5 5 5 2 Inner membrane component domain FGGY_C PF02782.16 EPS30840.1 - 4.9e-52 176.5 0.2 7.4e-52 176.0 0.2 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EPS30840.1 - 1e-21 77.6 0.0 2.3e-20 73.2 0.0 2.3 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 EPS30840.1 - 0.066 12.7 0.0 0.2 11.1 0.0 1.8 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family DEDD_Tnp_IS110 PF01548.17 EPS30840.1 - 0.092 12.6 0.9 1.9 8.3 0.1 2.3 2 0 0 2 2 2 0 Transposase GST_N_5 PF18485.1 EPS30841.1 - 0.19 12.1 0.1 0.38 11.1 0.1 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain F-box PF00646.33 EPS30842.1 - 0.00032 20.5 0.2 0.00072 19.4 0.2 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EPS30842.1 - 0.026 14.4 0.3 0.061 13.2 0.3 1.6 1 0 0 1 1 1 0 F-box-like Y_phosphatase PF00102.27 EPS30843.1 - 2.4e-59 200.8 0.0 1.9e-58 197.8 0.0 2.1 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 EPS30843.1 - 3.5e-08 33.9 0.0 1.1e-07 32.3 0.0 1.9 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.20 EPS30843.1 - 0.0075 16.1 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EPS30843.1 - 0.011 15.8 0.1 0.033 14.1 0.0 1.8 2 0 0 2 2 2 0 Tyrosine phosphatase family COX16 PF14138.6 EPS30844.1 - 6.5e-31 106.7 0.1 8.4e-31 106.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Arc_PepC_II PF06847.11 EPS30844.1 - 0.11 13.1 0.0 0.38 11.3 0.0 1.8 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II Nic96 PF04097.14 EPS30845.1 - 6.4e-221 735.1 0.0 8.3e-221 734.7 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.6 EPS30845.1 - 2.8e-07 31.3 34.9 2.8e-07 31.3 34.9 3.3 3 1 0 3 3 3 1 Nucleoporin FG repeat region RibD_C PF01872.17 EPS30846.1 - 1.2e-31 110.1 0.0 1.6e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 RibD C-terminal domain RCC1 PF00415.18 EPS30847.1 - 1.3e-55 185.8 3.2 8.3e-10 39.1 0.0 8.0 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EPS30847.1 - 3.9e-34 115.7 34.6 9.3e-09 34.9 1.5 6.6 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Presenilin PF01080.17 EPS30847.1 - 4.6 5.9 8.1 6.3 5.4 8.1 1.1 1 0 0 1 1 1 0 Presenilin Swi3 PF07962.12 EPS30848.1 - 2.2e-35 120.5 0.9 3.5e-35 119.8 0.9 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 NADH-u_ox-rdase PF10785.9 EPS30849.1 - 7.5e-30 103.4 0.1 1.3e-29 102.7 0.1 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.7 EPS30849.1 - 9.1e-26 89.7 0.0 1.2e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit dCMP_cyt_deam_1 PF00383.23 EPS30850.1 - 2.1e-25 88.5 0.0 3.5e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EPS30850.1 - 1.5e-21 76.6 0.0 2.1e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase XOO_2897-deam PF14440.6 EPS30850.1 - 0.0029 17.7 0.0 0.0058 16.7 0.0 1.5 1 0 0 1 1 1 1 Xanthomonas XOO_2897-like deaminase SNAD4 PF18750.1 EPS30850.1 - 0.0051 16.9 0.0 0.0082 16.3 0.0 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC3 PF18771.1 EPS30850.1 - 0.015 15.4 0.0 0.024 14.8 0.0 1.2 1 0 0 1 1 1 0 APOBEC3 APOBEC4_like PF18774.1 EPS30850.1 - 0.026 14.5 0.0 0.043 13.8 0.0 1.3 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase APOBEC2 PF18772.1 EPS30850.1 - 0.078 13.0 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 APOBEC2 NAD1 PF18778.1 EPS30850.1 - 0.13 12.4 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 NAD2 PF18782.1 EPS30850.1 - 0.19 11.9 0.0 0.27 11.3 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 Bd3614-deam PF14439.6 EPS30850.1 - 0.21 11.7 0.8 0.56 10.3 0.2 1.8 1 1 1 2 2 2 0 Bd3614-like deaminase PI3_PI4_kinase PF00454.27 EPS30851.1 - 2.1e-51 175.1 0.1 4.3e-51 174.2 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 EPS30851.1 - 1.1e-40 139.9 0.1 9.7e-40 136.8 0.0 2.4 2 0 0 2 2 2 1 FAT domain UME PF08064.13 EPS30851.1 - 9.4e-37 125.0 0.3 5.5e-36 122.6 0.3 2.5 1 0 0 1 1 1 1 UME (NUC010) domain FATC PF02260.20 EPS30851.1 - 3.9e-14 52.2 0.0 9.3e-14 51.0 0.0 1.7 1 0 0 1 1 1 1 FATC domain TPR_7 PF13176.6 EPS30851.1 - 0.0032 17.4 0.6 7.7 6.8 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EPS30851.1 - 0.0041 17.8 1.8 10 7.3 0.3 4.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EPS30851.1 - 0.0048 17.4 0.2 1 9.9 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EPS30851.1 - 0.05 13.3 2.6 0.48 10.1 0.5 3.1 3 0 0 3 3 3 0 TPR repeat RTP1_C1 PF10363.9 EPS30851.1 - 0.07 13.3 1.0 2.2 8.5 0.0 3.5 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 ApoLp-III PF07464.11 EPS30851.1 - 0.12 12.5 0.5 0.58 10.2 0.5 2.2 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) RRM_1 PF00076.22 EPS30852.1 - 3.8e-14 52.2 0.0 5.4e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EPS30852.1 - 0.0037 16.8 0.0 0.0059 16.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EPS30852.1 - 0.014 15.5 0.0 0.022 14.8 0.0 1.2 1 0 0 1 1 1 0 RNA binding motif RRM_7 PF16367.5 EPS30852.1 - 0.17 12.0 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif AAA PF00004.29 EPS30853.1 - 1.3e-65 219.8 0.0 1.2e-41 142.2 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EPS30853.1 - 2.9e-17 62.2 1.2 4.1e-11 42.5 0.4 2.9 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EPS30853.1 - 7.1e-12 46.0 1.3 0.0056 17.1 0.0 4.9 3 2 1 5 5 4 2 AAA ATPase domain AAA_5 PF07728.14 EPS30853.1 - 8.2e-09 35.6 0.4 0.0047 16.9 0.2 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Bac_DnaA PF00308.18 EPS30853.1 - 4.6e-08 33.2 0.0 1.2e-06 28.6 0.0 2.6 2 2 0 2 2 2 1 Bacterial dnaA protein AAA_22 PF13401.6 EPS30853.1 - 1.8e-07 31.5 2.2 0.2 11.9 0.0 4.3 2 2 2 4 4 4 2 AAA domain RuvB_N PF05496.12 EPS30853.1 - 4.7e-07 29.7 0.0 0.016 14.9 0.0 4.1 4 0 0 4 4 4 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 EPS30853.1 - 5.4e-07 29.3 0.0 0.008 15.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region Rad17 PF03215.15 EPS30853.1 - 1.2e-06 28.6 0.1 0.0003 20.8 0.0 3.0 2 1 1 3 3 3 1 Rad17 P-loop domain AAA_25 PF13481.6 EPS30853.1 - 3.8e-06 26.6 0.5 0.46 10.0 0.0 4.4 3 1 1 4 4 4 1 AAA domain AAA_14 PF13173.6 EPS30853.1 - 6e-06 26.3 0.0 0.049 13.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 EPS30853.1 - 3e-05 24.3 0.0 0.16 12.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 EPS30853.1 - 4.3e-05 22.9 0.6 0.037 13.2 0.0 2.7 3 0 0 3 3 3 2 TIP49 P-loop domain AAA_2 PF07724.14 EPS30853.1 - 6.4e-05 23.1 0.0 0.0078 16.3 0.0 2.9 2 2 0 2 2 2 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 EPS30853.1 - 0.00022 21.0 0.0 0.28 10.9 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.22 EPS30853.1 - 0.00025 21.4 0.0 1.4 9.4 0.0 2.6 2 0 0 2 2 2 2 RNA helicase DUF815 PF05673.13 EPS30853.1 - 0.00034 19.9 0.0 0.32 10.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) ATPase_2 PF01637.18 EPS30853.1 - 0.00035 20.6 0.6 0.036 14.0 0.0 3.2 2 2 1 3 3 3 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EPS30853.1 - 0.0018 18.0 0.0 0.15 11.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 EPS30853.1 - 0.005 16.8 0.0 1.9 8.5 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 EPS30853.1 - 0.0059 16.0 0.1 3 7.2 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI TniB PF05621.11 EPS30853.1 - 0.012 15.0 0.0 5.5 6.3 0.0 3.1 3 0 0 3 3 3 0 Bacterial TniB protein AAA_18 PF13238.6 EPS30853.1 - 0.012 16.1 0.0 2 8.9 0.0 3.0 3 0 0 3 3 2 0 AAA domain Vps4_C PF09336.10 EPS30853.1 - 0.016 15.2 0.0 0.25 11.3 0.0 2.9 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain NACHT PF05729.12 EPS30853.1 - 0.017 15.1 1.6 0.28 11.1 0.2 3.1 2 2 1 3 3 3 0 NACHT domain AAA_33 PF13671.6 EPS30853.1 - 0.028 14.6 0.0 13 6.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EPS30853.1 - 0.033 14.0 0.1 3 7.6 0.0 2.6 3 0 0 3 3 2 0 AAA domain MCM PF00493.23 EPS30853.1 - 0.035 13.2 0.0 5.1 6.1 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain AAA_30 PF13604.6 EPS30853.1 - 0.045 13.5 0.5 2 8.1 0.0 2.8 3 0 0 3 3 2 0 AAA domain ABC_tran PF00005.27 EPS30853.1 - 0.069 13.7 0.1 8.6 6.9 0.0 2.8 2 0 0 2 2 2 0 ABC transporter AAA_19 PF13245.6 EPS30853.1 - 0.12 12.8 0.0 24 5.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EPS30853.1 - 0.12 12.9 0.0 0.37 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EPS30853.1 - 0.17 11.2 0.7 8 5.7 0.1 2.8 2 2 0 2 2 2 0 KaiC Viral_helicase1 PF01443.18 EPS30853.1 - 0.18 11.5 0.2 41 3.8 0.0 3.0 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Ras PF00071.22 EPS30854.1 - 1.8e-65 219.5 0.1 2.1e-65 219.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EPS30854.1 - 6.8e-34 116.7 0.1 9.6e-34 116.2 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPS30854.1 - 4e-14 52.5 0.0 5.2e-14 52.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EPS30854.1 - 3.1e-06 26.9 0.0 5.5e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EPS30854.1 - 9.3e-05 21.9 0.0 0.00011 21.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EPS30854.1 - 0.00048 20.1 0.1 0.48 10.3 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EPS30854.1 - 0.0032 17.5 0.0 0.0061 16.6 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EPS30854.1 - 0.022 14.3 0.0 0.1 12.1 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B SRPRB PF09439.10 EPS30854.1 - 0.024 14.1 0.0 0.029 13.8 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 EPS30854.1 - 0.14 12.4 0.1 0.48 10.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EPS30854.1 - 0.16 12.4 0.0 8.4 6.8 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NCA2 PF08637.10 EPS30855.1 - 1.1e-103 346.5 0.2 2e-103 345.5 0.2 1.5 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 FA_hydroxylase PF04116.13 EPS30856.1 - 4.1e-26 91.9 17.0 7.5e-26 91.0 17.0 1.4 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily zf-CCHC PF00098.23 EPS30858.1 - 0.17 12.0 2.8 0.36 11.0 2.8 1.6 1 0 0 1 1 1 0 Zinc knuckle rve PF00665.26 EPS30859.1 - 2.3e-15 56.8 0.0 4.4e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain RT_RNaseH_2 PF17919.1 EPS30859.1 - 2.3e-08 34.0 0.0 0.00027 20.9 0.0 2.5 1 1 1 2 2 2 2 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 EPS30859.1 - 6e-05 23.3 0.0 0.00012 22.3 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase rve_3 PF13683.6 EPS30859.1 - 0.029 14.2 0.0 0.083 12.7 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain Mto2_bdg PF12808.7 EPS30859.1 - 0.059 13.7 0.6 0.17 12.2 0.6 1.7 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region RVT_1 PF00078.27 EPS30859.1 - 0.082 12.4 0.0 4.6 6.7 0.0 2.2 1 1 1 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) ATP-cone PF03477.16 EPS30860.1 - 0.075 13.6 0.0 0.24 12.0 0.0 1.8 1 0 0 1 1 1 0 ATP cone domain PPR_1 PF12854.7 EPS30861.1 - 0.039 13.6 0.2 0.057 13.1 0.2 1.4 1 0 0 1 1 1 0 PPR repeat Sigma_1s PF02454.16 EPS30862.1 - 0.1 12.6 0.1 0.3 11.1 0.0 1.8 2 0 0 2 2 2 0 Sigma 1s protein HD_4 PF13328.6 EPS30862.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 HD domain HTH_psq PF05225.16 EPS30863.1 - 7.1e-06 25.7 0.0 1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 helix-turn-helix, Psq domain CHASE6_C PF17150.4 EPS30864.1 - 0.07 13.8 0.2 0.075 13.7 0.2 1.0 1 0 0 1 1 1 0 C-terminal domain of two-partite extracellular sensor domain HK97-gp10_like PF04883.12 EPS30864.1 - 0.49 11.4 3.2 0.59 11.2 3.0 1.3 1 1 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component DUF3439 PF11921.8 EPS30864.1 - 0.76 9.8 8.0 0.8 9.7 8.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) YpjP PF14005.6 EPS30865.1 - 0.0081 16.2 0.4 0.009 16.1 0.4 1.1 1 0 0 1 1 1 1 YpjP-like protein Mor PF08765.11 EPS30865.1 - 0.097 12.7 3.1 0.78 9.7 0.6 2.1 1 1 1 2 2 2 0 Mor transcription activator family Arm-DNA-bind_2 PF12167.8 EPS30865.1 - 1.4 8.9 6.7 13 5.8 6.7 2.3 1 1 0 1 1 1 0 Arm DNA-binding domain FGF-BP1 PF06473.12 EPS30866.1 - 0.045 13.6 0.1 0.045 13.6 0.1 2.2 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) RNA_pol_N PF01194.17 EPS30867.1 - 7.9e-31 106.1 1.7 9.4e-31 105.9 1.7 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit WD40 PF00400.32 EPS30868.1 - 0.0018 19.0 13.4 0.013 16.4 0.3 6.2 7 1 0 7 7 7 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS30868.1 - 0.0073 16.6 0.1 15 5.9 0.0 3.7 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Kelch_6 PF13964.6 EPS30868.1 - 0.13 12.6 0.2 0.94 9.9 0.1 2.5 2 0 0 2 2 2 0 Kelch motif Clr5 PF14420.6 EPS30869.1 - 2.9e-20 72.2 3.4 4.7e-20 71.5 1.5 2.5 2 0 0 2 2 2 1 Clr5 domain 4HBT_3 PF13622.6 EPS30869.1 - 2.7 8.2 5.6 5.6 7.1 5.6 1.5 1 0 0 1 1 1 0 Thioesterase-like superfamily Mito_fiss_reg PF05308.11 EPS30869.1 - 2.9 7.9 15.9 0.23 11.5 9.3 2.3 2 1 0 2 2 2 0 Mitochondrial fission regulator Het-C PF07217.11 EPS30872.1 - 6.6e-246 817.2 0.0 8.5e-246 816.9 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Gly-zipper_Omp PF13488.6 EPS30872.1 - 3.4 7.7 13.5 7.3 6.7 13.5 1.5 1 0 0 1 1 1 0 Glycine zipper FAD_binding_4 PF01565.23 EPS30873.1 - 1.6e-38 131.6 0.0 3.3e-38 130.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.19 EPS30873.1 - 1.8e-35 122.8 0.1 3e-35 122.1 0.1 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Serinc PF03348.15 EPS30873.1 - 0.19 10.6 0.5 0.27 10.1 0.5 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) ADH_N PF08240.12 EPS30874.1 - 3.5e-35 120.2 0.4 9.6e-35 118.8 0.4 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPS30874.1 - 7.7e-22 77.7 0.2 1.2e-21 77.0 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EPS30874.1 - 3.2e-10 39.8 0.2 5.4e-10 39.1 0.2 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus UDPG_MGDP_dh_N PF03721.14 EPS30874.1 - 0.00021 21.0 0.0 0.00034 20.3 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ADH_zinc_N_2 PF13602.6 EPS30874.1 - 0.0011 20.0 0.0 0.0023 19.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EPS30874.1 - 0.0014 17.9 0.6 0.0026 17.1 0.6 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 EPS30874.1 - 0.002 17.4 0.3 0.0064 15.8 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EPS30874.1 - 0.02 14.1 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_25 PF13649.6 EPS30874.1 - 0.023 15.4 0.0 0.05 14.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain HI0933_like PF03486.14 EPS30874.1 - 0.035 12.8 0.2 0.051 12.3 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein 2-Hacid_dh_C PF02826.19 EPS30874.1 - 0.071 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 EPS30874.1 - 0.089 13.4 0.3 2.2 8.9 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Ras PF00071.22 EPS30875.1 - 3.9e-39 133.8 0.0 5.6e-39 133.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EPS30875.1 - 1.8e-26 92.7 0.0 2.6e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPS30875.1 - 7.5e-11 41.8 0.0 9.4e-10 38.2 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EPS30875.1 - 0.0029 17.7 0.0 0.0048 17.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EPS30875.1 - 0.0037 16.6 0.0 0.0051 16.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_33 PF13671.6 EPS30875.1 - 0.058 13.6 0.0 0.098 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EPS30875.1 - 0.058 13.3 0.0 0.24 11.3 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 EPS30875.1 - 0.1 13.1 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 EPS30875.1 - 0.11 12.9 0.0 0.68 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.6 EPS30875.1 - 0.16 12.2 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 EPS30875.1 - 0.23 10.9 0.0 0.4 10.1 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit V_ATPase_I PF01496.19 EPS30879.1 - 0.26 9.1 1.1 0.4 8.5 1.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Glyco_tranf_2_3 PF13641.6 EPS30883.1 - 8.3e-32 110.9 0.0 1.1e-31 110.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EPS30883.1 - 2.4e-09 37.2 0.0 4e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EPS30883.1 - 5.8e-06 25.9 0.0 3.7e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 21 ATP12 PF07542.11 EPS30884.1 - 3.8e-45 153.1 0.2 8.2e-45 152.0 0.2 1.6 2 0 0 2 2 2 1 ATP12 chaperone protein AP2 PF00847.20 EPS30884.1 - 0.028 14.7 0.1 0.1 12.9 0.0 1.9 2 0 0 2 2 2 0 AP2 domain Oxysterol_BP PF01237.18 EPS30885.1 - 2.6e-134 447.8 0.1 5.7e-133 443.3 0.0 2.4 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.7 EPS30885.1 - 9e-16 58.2 0.7 9.4e-08 32.5 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EPS30885.1 - 2.3e-13 50.1 1.2 1.7e-07 31.3 0.2 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EPS30885.1 - 7.9e-13 48.2 0.2 0.0013 19.1 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat PH PF00169.29 EPS30885.1 - 8.8e-11 42.3 0.5 2e-10 41.1 0.5 1.7 1 0 0 1 1 1 1 PH domain Ank_4 PF13637.6 EPS30885.1 - 2.2e-10 40.9 0.1 1.1e-05 25.9 0.0 3.8 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPS30885.1 - 5.2e-10 38.7 0.1 0.012 16.1 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat PH_8 PF15409.6 EPS30885.1 - 2.9e-06 27.5 0.8 8.1e-06 26.0 0.8 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 EPS30885.1 - 6e-05 23.4 2.3 6e-05 23.4 2.3 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain LLC1 PF14945.6 EPS30885.1 - 0.11 13.1 1.4 0.41 11.2 1.4 1.9 1 0 0 1 1 1 0 Normal lung function maintenance, Low in Lung Cancer 1 protein zf-Mss51 PF13824.6 EPS30886.1 - 4.4e-28 97.1 6.3 9.5e-28 96.1 6.3 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 EPS30886.1 - 0.035 14.2 0.5 0.035 14.2 0.5 2.1 2 0 0 2 2 2 0 MYND finger DUF3011 PF11218.8 EPS30886.1 - 0.061 13.3 0.0 0.099 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3011) zf-HIT PF04438.16 EPS30886.1 - 0.11 12.4 2.2 2 8.4 0.3 2.5 2 0 0 2 2 2 0 HIT zinc finger ADH_zinc_N PF00107.26 EPS30887.1 - 1.1e-29 103.0 0.9 1.1e-29 103.0 0.9 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPS30887.1 - 2.8e-10 41.3 0.1 5.1e-10 40.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPS30887.1 - 1.1e-05 25.2 0.0 0.0001 22.1 0.0 2.5 3 1 1 4 4 4 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 EPS30887.1 - 0.003 17.1 0.4 0.0049 16.4 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase TrkA_N PF02254.18 EPS30887.1 - 0.0064 16.7 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.21 EPS30887.1 - 0.02 14.2 0.4 0.035 13.4 0.4 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short_C2 PF13561.6 EPS30887.1 - 0.04 13.5 1.0 0.067 12.7 1.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase HupF_HypC PF01455.18 EPS30887.1 - 0.08 13.1 0.4 0.3 11.3 0.1 2.1 2 0 0 2 2 2 0 HupF/HypC family Clr5 PF14420.6 EPS30888.1 - 1.3e-12 47.7 1.8 1.3e-12 47.7 1.8 2.1 2 0 0 2 2 2 1 Clr5 domain MEF2_binding PF09047.10 EPS30889.1 - 0.74 9.7 3.6 0.69 9.8 1.2 2.2 2 1 0 2 2 2 0 MEF2 binding SNF2_N PF00176.23 EPS30892.1 - 6.9e-65 219.1 0.2 1.1e-64 218.3 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EPS30892.1 - 5.3e-19 68.6 0.0 1.5e-18 67.1 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPS30892.1 - 3.5e-10 40.1 0.0 8e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HSA PF07529.13 EPS30892.1 - 9.4e-08 32.3 8.9 1e-07 32.2 6.9 2.2 2 0 0 2 2 2 1 HSA DEAD PF00270.29 EPS30892.1 - 0.00036 20.4 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF5045 PF16464.5 EPS30892.1 - 0.029 14.7 0.0 0.082 13.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5045) DEAD_2 PF06733.15 EPS30892.1 - 0.046 13.4 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 DEAD_2 NDUF_B8 PF05821.11 EPS30893.1 - 9.1e-09 35.4 0.3 1.5e-08 34.7 0.3 1.3 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Membr_traf_MHD PF10540.9 EPS30894.1 - 5.3e-21 75.4 0.3 3.2e-10 40.4 0.4 3.7 2 1 1 3 3 3 2 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 EPS30894.1 - 7.1e-15 55.2 0.0 1.5e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 C2 domain AIG2_2 PF13772.6 EPS30895.1 - 0.0015 18.9 0.7 0.014 15.8 0.1 2.4 2 1 0 2 2 2 1 AIG2-like family Pribosyltran PF00156.27 EPS30896.1 - 5.3e-14 52.0 0.0 7.5e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Thi4 PF01946.17 EPS30896.1 - 0.01 15.1 0.3 0.016 14.5 0.3 1.2 1 0 0 1 1 1 0 Thi4 family UPRTase PF14681.6 EPS30896.1 - 0.06 12.8 0.0 0.081 12.3 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Ribonuc_L-PSP PF01042.21 EPS30898.1 - 4.1e-41 139.8 0.1 4.6e-41 139.6 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Glyco_hydro_47 PF01532.20 EPS30899.1 - 1.9e-114 383.1 0.0 2.6e-114 382.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 WD40 PF00400.32 EPS30901.1 - 9.3e-40 133.9 7.0 7e-07 29.8 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS30901.1 - 1e-10 41.7 0.1 0.056 13.7 0.0 5.0 2 2 5 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EPS30901.1 - 0.0031 16.9 0.0 0.71 9.1 0.0 3.2 2 1 1 3 3 3 1 WD40-like domain Nucleoporin_N PF08801.11 EPS30901.1 - 0.067 11.9 0.3 1.8 7.2 0.1 2.6 2 1 1 3 3 3 0 Nup133 N terminal like PQQ_2 PF13360.6 EPS30901.1 - 0.081 12.5 0.1 2 7.9 0.0 2.7 2 1 0 3 3 3 0 PQQ-like domain TRAPP PF04051.16 EPS30902.1 - 1.5e-35 122.1 0.0 1.8e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF4250 PF14056.6 EPS30902.1 - 0.014 15.3 0.1 0.032 14.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) PNGaseA PF12222.8 EPS30902.1 - 0.022 13.6 0.0 0.027 13.4 0.0 1.1 1 0 0 1 1 1 0 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A LisH PF08513.11 EPS30904.1 - 3.2e-05 23.7 0.2 5.9e-05 22.9 0.2 1.4 1 0 0 1 1 1 1 LisH PEGSRP PF07623.11 EPS30904.1 - 0.1 12.4 2.8 19 5.2 2.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1584) SUZ PF12752.7 EPS30905.1 - 4 8.3 8.9 5.4 7.9 8.9 1.3 1 0 0 1 1 1 0 SUZ domain RRM_1 PF00076.22 EPS30908.1 - 6.1e-46 154.1 0.0 7.5e-17 60.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EPS30908.1 - 7.6e-06 25.8 0.1 0.0015 18.5 0.0 3.0 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EPS30908.1 - 9.7e-05 22.2 0.0 0.057 13.3 0.0 2.9 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_3 PF08777.11 EPS30908.1 - 0.00013 22.0 0.0 0.0012 18.8 0.0 2.3 3 0 0 3 3 3 1 RNA binding motif RRM_7 PF16367.5 EPS30908.1 - 0.00062 19.8 0.1 0.051 13.7 0.0 2.8 3 1 0 3 3 3 1 RNA recognition motif RRM_5 PF13893.6 EPS30908.1 - 0.0076 15.8 0.0 0.055 13.1 0.0 2.3 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 EPS30908.1 - 0.1 12.8 0.1 13 5.9 0.0 3.4 3 1 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter UPF0154 PF03672.13 EPS30908.1 - 0.21 11.7 1.6 0.43 10.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) TFB6 PF17110.5 EPS30910.1 - 2.8e-29 102.0 0.0 4.6e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 Subunit 11 of the general transcription factor TFIIH RRP7 PF12923.7 EPS30911.1 - 2.3e-27 95.5 11.9 2.3e-27 95.5 11.9 1.5 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 EPS30911.1 - 8.7e-27 93.9 0.0 1.7e-26 93.0 0.0 1.4 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain Dak1_2 PF13684.6 EPS30911.1 - 0.029 13.4 0.7 0.077 12.1 0.3 1.7 2 0 0 2 2 2 0 Dihydroxyacetone kinase family ORC_WH_C PF18137.1 EPS30911.1 - 0.17 12.0 2.8 0.37 10.9 2.8 1.5 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal Rad51 PF08423.11 EPS30912.1 - 1.2e-113 378.6 0.0 1.5e-113 378.3 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 EPS30912.1 - 1.3e-10 41.3 0.0 1.7e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 EPS30912.1 - 4e-08 33.7 1.5 6.8e-08 33.0 0.5 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 EPS30912.1 - 1.9e-07 30.7 0.0 4.6e-07 29.4 0.0 1.7 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 EPS30912.1 - 1.3e-05 24.9 0.0 1.8e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.15 EPS30912.1 - 0.023 14.0 0.1 0.18 11.1 0.0 2.1 1 1 1 2 2 2 0 DnaB-like helicase C terminal domain PAXNEB PF05625.11 EPS30912.1 - 0.14 11.3 0.0 1.2 8.2 0.0 2.0 2 0 0 2 2 2 0 PAXNEB protein RNA_pol_A_CTD PF03118.15 EPS30912.1 - 0.16 11.8 0.1 0.34 10.7 0.1 1.5 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain zf-CCHC PF00098.23 EPS30913.1 - 3.4e-46 153.3 57.4 2.2e-07 30.7 3.4 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 EPS30913.1 - 1.2e-09 37.7 39.5 0.042 13.6 0.4 7.1 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.6 EPS30913.1 - 3.5e-07 30.1 40.6 0.024 14.6 0.1 7.0 4 2 2 6 6 6 4 Zinc knuckle zf-CCHC_5 PF14787.6 EPS30913.1 - 0.00026 20.6 40.9 0.021 14.6 0.9 7.1 4 2 3 7 7 7 5 GAG-polyprotein viral zinc-finger DUF5401 PF17380.2 EPS30913.1 - 2.3 6.2 3.0 2.8 5.9 3.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) UDPGP PF01704.18 EPS30914.1 - 2.5e-54 184.5 0.0 3.3e-54 184.1 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Pro_isomerase PF00160.21 EPS30915.1 - 1.5e-33 116.3 0.0 2.2e-33 115.7 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 EPS30915.1 - 1.3e-15 57.0 0.0 3e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Zn_clus PF00172.18 EPS30917.1 - 1.6e-08 34.5 6.8 3.1e-08 33.6 6.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S24e PF01282.19 EPS30918.1 - 1.4e-35 121.1 0.3 2.2e-35 120.4 0.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e RRXRR PF14239.6 EPS30918.1 - 0.0072 16.2 2.1 0.0094 15.8 2.0 1.4 1 1 0 1 1 1 1 RRXRR protein FAD_binding_4 PF01565.23 EPS30918.1 - 0.02 14.6 0.0 0.027 14.2 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain Methyltransf_16 PF10294.9 EPS30919.1 - 2.2e-17 63.4 0.0 3.4e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Met_10 PF02475.16 EPS30919.1 - 0.0002 21.2 0.0 0.00033 20.5 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.6 EPS30919.1 - 0.011 15.5 0.0 0.024 14.4 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 EPS30919.1 - 0.012 15.0 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EPS30919.1 - 0.014 15.0 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.6 EPS30919.1 - 0.015 16.0 0.0 0.041 14.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 EPS30919.1 - 0.016 15.0 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF938 PF06080.12 EPS30919.1 - 0.051 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) FPP PF05911.11 EPS30920.1 - 0.5 8.5 28.0 0.099 10.8 22.1 2.0 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil Fez1 PF06818.15 EPS30920.1 - 2.9 8.3 29.3 9.7 6.6 22.7 2.6 2 1 0 2 2 2 0 Fez1 Bacillus_HBL PF05791.11 EPS30920.1 - 3.1 7.6 6.5 5 6.9 0.3 2.5 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DivIVA PF05103.13 EPS30920.1 - 9 6.4 26.2 8.2 6.5 3.4 3.3 2 1 1 3 3 3 0 DivIVA protein CLTH PF10607.9 EPS30922.1 - 1.1e-32 113.0 0.0 1.7e-32 112.4 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 EPS30922.1 - 2.4e-25 89.0 0.1 3.8e-25 88.3 0.1 1.3 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 EPS30922.1 - 0.013 15.5 0.4 0.035 14.1 0.1 2.0 2 0 0 2 2 2 0 LisH INO80_Ies4 PF08193.11 EPS30923.1 - 1.4e-64 218.4 15.9 1.7e-64 218.1 15.9 1.2 1 0 0 1 1 1 1 INO80 complex subunit Ies4 DnaJ PF00226.31 EPS30925.1 - 2.2e-16 59.8 0.0 4.2e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain RPA43_OB PF17875.1 EPS30926.1 - 1.1e-38 132.7 0.0 1.1e-38 132.7 0.0 2.8 3 0 0 3 3 3 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 EPS30926.1 - 5.8e-06 26.6 0.0 1.4e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Coilin_N PF15862.5 EPS30926.1 - 0.0095 15.7 9.7 0.0095 15.7 9.7 2.3 2 0 0 2 2 2 1 Coilin N-terminus DDHD PF02862.17 EPS30926.1 - 1.5 8.9 6.6 6.9 6.8 3.4 2.2 2 0 0 2 2 2 0 DDHD domain SR-25 PF10500.9 EPS30926.1 - 2.5 7.6 29.3 0.077 12.6 13.6 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Presenilin PF01080.17 EPS30926.1 - 2.7 6.6 8.5 3.4 6.3 5.5 2.0 2 0 0 2 2 2 0 Presenilin GAGA_bind PF06217.12 EPS30926.1 - 7.1 6.8 13.4 0.34 11.2 5.4 2.0 2 0 0 2 2 2 0 GAGA binding protein-like family Pyr_redox_2 PF07992.14 EPS30927.1 - 1.1e-50 172.6 0.3 1.3e-50 172.3 0.3 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.26 EPS30927.1 - 1.6e-16 60.0 0.1 3.6e-16 58.9 0.1 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.27 EPS30927.1 - 7.5e-14 52.0 4.4 4.7e-12 46.3 0.4 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 EPS30927.1 - 2.1e-08 34.6 0.0 1.3e-07 32.1 0.0 2.2 2 0 0 2 2 2 1 Reductase C-terminal NAD_binding_9 PF13454.6 EPS30927.1 - 2.8e-05 24.2 0.4 0.36 10.8 0.0 3.2 3 0 0 3 3 3 2 FAD-NAD(P)-binding Rieske_2 PF13806.6 EPS30927.1 - 0.00015 21.7 0.0 0.00046 20.1 0.0 1.9 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain DUF1188 PF06690.11 EPS30927.1 - 0.00026 20.6 0.0 0.00046 19.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1188) K_oxygenase PF13434.6 EPS30927.1 - 0.00066 18.9 0.1 0.87 8.7 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.18 EPS30927.1 - 0.0073 16.6 1.5 2.2 8.6 0.1 3.0 3 0 0 3 3 3 2 TrkA-N domain AMPK1_CBM PF16561.5 EPS30929.1 - 0.00016 21.9 0.0 0.00027 21.1 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Spc7_N PF15402.6 EPS30929.1 - 0.97 7.6 8.8 1.2 7.3 8.8 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Fungal_trans PF04082.18 EPS30930.1 - 3.1e-19 69.0 0.1 5.1e-19 68.3 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_3 PF07859.13 EPS30931.1 - 1.1e-15 58.1 0.0 9.4e-09 35.4 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EPS30931.1 - 5.4e-10 39.1 0.0 1.4e-05 24.6 0.0 2.5 2 1 0 2 2 2 2 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EPS30931.1 - 2.2e-07 30.8 0.0 8.3e-07 28.9 0.0 1.9 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) COesterase PF00135.28 EPS30931.1 - 4.4e-06 25.8 0.3 7.9e-06 25.0 0.0 1.4 2 0 0 2 2 2 1 Carboxylesterase family Esterase PF00756.20 EPS30931.1 - 4.4e-06 26.5 0.0 0.036 13.7 0.0 2.2 2 0 0 2 2 2 2 Putative esterase Abhydrolase_1 PF00561.20 EPS30931.1 - 5.4e-06 26.2 0.1 1.1e-05 25.2 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EPS30931.1 - 0.00039 20.3 0.0 0.21 11.4 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase DLH PF01738.18 EPS30931.1 - 0.00095 18.8 0.0 0.93 9.0 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Hydrolase_4 PF12146.8 EPS30931.1 - 0.00099 18.4 0.0 0.023 14.0 0.0 2.5 1 1 1 2 2 2 1 Serine aminopeptidase, S33 LIP PF03583.14 EPS30931.1 - 0.0017 17.7 0.0 0.12 11.7 0.0 2.3 2 0 0 2 2 2 1 Secretory lipase Say1_Mug180 PF10340.9 EPS30931.1 - 0.011 14.7 0.0 0.023 13.6 0.0 1.5 1 1 0 1 1 1 0 Steryl acetyl hydrolase AXE1 PF05448.12 EPS30931.1 - 0.038 12.6 0.0 0.56 8.8 0.0 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) IDO PF01231.18 EPS30932.1 - 2.8e-30 105.5 0.1 3.8e-29 101.8 0.0 2.1 1 1 0 2 2 2 1 Indoleamine 2,3-dioxygenase Cyt-b5 PF00173.28 EPS30932.1 - 1.6e-15 57.0 0.0 3.4e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Helicase_Sgs1 PF11408.8 EPS30932.1 - 0.1 12.7 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 Sgs1 RecQ helicase p450 PF00067.22 EPS30933.1 - 2.5e-71 240.8 0.0 2.8e-71 240.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Trm56 PF01994.16 EPS30933.1 - 0.12 12.3 0.0 2.4 8.1 0.0 2.4 2 0 0 2 2 2 0 tRNA ribose 2'-O-methyltransferase, aTrm56 NiFe_hyd_3_EhaA PF17367.2 EPS30934.1 - 0.54 10.4 4.9 2.4 8.4 4.9 2.2 1 1 0 1 1 1 0 NiFe-hydrogenase-type-3 Eha complex subunit A Trp_DMAT PF11991.8 EPS30935.1 - 2.2e-08 33.9 0.1 5.9e-08 32.5 0.1 1.7 1 1 0 1 1 1 1 Tryptophan dimethylallyltransferase Glyco_hydro_18 PF00704.28 EPS30936.1 - 1.6e-05 24.8 0.0 1.7e-05 24.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Nucleopor_Nup85 PF07575.13 EPS30939.1 - 1.4e-26 93.3 0.0 1e-16 60.7 0.0 3.3 3 1 0 3 3 3 2 Nup85 Nucleoporin GCIP PF13324.6 EPS30939.1 - 0.032 13.8 0.0 0.077 12.6 0.0 1.6 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Fungal_trans_2 PF11951.8 EPS30942.1 - 1.6e-11 43.6 0.2 2.2e-11 43.2 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS30942.1 - 4.1e-09 36.4 10.2 7.3e-09 35.6 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.12 EPS30943.1 - 2.7e-22 78.7 1.1 4.5e-22 78.0 1.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPS30943.1 - 5.8e-20 71.6 0.0 1e-19 70.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPS30943.1 - 4.1e-08 34.3 0.0 6.6e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EPS30943.1 - 0.00063 19.1 0.1 0.001 18.4 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EPS30943.1 - 0.00087 18.7 0.2 0.0015 17.9 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain KR PF08659.10 EPS30943.1 - 0.065 13.1 0.3 0.12 12.3 0.3 1.4 1 0 0 1 1 1 0 KR domain NMO PF03060.15 EPS30943.1 - 0.071 12.5 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase AP_endonuc_2 PF01261.24 EPS30944.1 - 0.05 13.0 0.0 0.056 12.9 0.0 1.1 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel DnaJ PF00226.31 EPS30946.1 - 1.4e-07 31.6 3.9 2.9e-07 30.5 3.9 1.5 1 0 0 1 1 1 1 DnaJ domain Ctr PF04145.15 EPS30947.1 - 2.3e-38 132.1 3.3 3.1e-38 131.7 3.3 1.2 1 0 0 1 1 1 1 Ctr copper transporter family Bac_export_2 PF01312.19 EPS30947.1 - 0.04 13.1 1.2 0.055 12.7 0.2 1.7 2 0 0 2 2 2 0 FlhB HrpN YscU SpaS Family Sensor PF13796.6 EPS30947.1 - 0.15 12.1 4.6 2.8 8.0 0.1 2.0 1 1 1 2 2 2 0 Putative sensor DUF2530 PF10745.9 EPS30947.1 - 0.44 10.8 2.9 4.5 7.6 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) LapA_dom PF06305.11 EPS30947.1 - 5.9 6.8 5.9 27 4.7 0.1 2.5 2 1 0 2 2 2 0 Lipopolysaccharide assembly protein A domain SnoaL_2 PF12680.7 EPS30948.1 - 0.00059 20.4 0.0 0.00086 19.9 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF3261 PF11659.8 EPS30948.1 - 0.1 12.4 0.1 0.22 11.3 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3261) ADIP PF11559.8 EPS30951.1 - 3.3e-42 144.1 9.5 3.3e-42 144.1 9.5 3.5 4 0 0 4 4 4 1 Afadin- and alpha -actinin-Binding FlaC_arch PF05377.11 EPS30951.1 - 0.6 10.6 4.6 1.9 9.0 0.4 3.7 3 1 0 4 4 4 0 Flagella accessory protein C (FlaC) LRR_4 PF12799.7 EPS30952.1 - 9.8e-07 29.0 10.2 3.1 8.4 0.4 7.1 6 1 2 9 9 9 3 Leucine Rich repeats (2 copies) TPR_2 PF07719.17 EPS30952.1 - 4.6e-06 26.3 6.1 0.02 15.0 0.7 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat F-box-like PF12937.7 EPS30952.1 - 0.00023 21.0 0.1 0.00052 19.8 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EPS30952.1 - 0.00051 19.9 0.3 0.0016 18.3 0.3 1.9 1 0 0 1 1 1 1 F-box domain LRR_8 PF13855.6 EPS30952.1 - 0.0038 17.0 5.2 4.1 7.2 0.0 4.8 4 1 0 5 5 5 2 Leucine rich repeat TPR_19 PF14559.6 EPS30952.1 - 0.0067 16.9 0.1 0.33 11.5 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat LRR_1 PF00560.33 EPS30952.1 - 0.0072 16.7 2.3 26 5.9 0.2 5.6 5 1 0 5 5 4 0 Leucine Rich Repeat TPR_11 PF13414.6 EPS30952.1 - 0.022 14.4 0.1 0.052 13.2 0.1 1.6 1 0 0 1 1 1 0 TPR repeat TPR_12 PF13424.6 EPS30952.1 - 0.041 14.2 1.3 21 5.5 0.1 3.1 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EPS30952.1 - 0.053 13.4 8.3 0.094 12.6 0.6 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EPS30952.1 - 0.072 13.9 0.3 17 6.6 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat IDO PF01231.18 EPS30953.1 - 3.8e-35 121.5 0.0 5.6e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF5343 PF17278.2 EPS30953.1 - 0.19 11.8 0.0 0.49 10.5 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5343) PET117 PF15786.5 EPS30954.1 - 4.4e-23 81.3 1.0 5.2e-23 81.1 1.0 1.1 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial RPA_interact_M PF14767.6 EPS30954.1 - 0.0065 17.0 3.9 0.0091 16.6 3.9 1.1 1 0 0 1 1 1 1 Replication protein A interacting middle DUF3824 PF12868.7 EPS30954.1 - 0.056 14.1 0.1 0.061 14.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) EF-1_beta_acid PF10587.9 EPS30954.1 - 1.4 9.4 6.0 0.75 10.3 3.6 1.8 1 1 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region V-ATPase_G PF03179.15 EPS30955.1 - 6e-33 113.5 20.6 6.9e-33 113.3 20.6 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 EPS30955.1 - 0.051 13.7 24.7 0.042 13.9 13.1 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) DUF3552 PF12072.8 EPS30955.1 - 0.18 11.2 23.5 0.041 13.3 12.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) HOIP-UBA PF16678.5 EPS30955.1 - 0.26 11.3 8.0 0.5 10.4 8.0 1.3 1 1 0 1 1 1 0 HOIP UBA domain pair V-ATPase_G_2 PF16999.5 EPS30955.1 - 0.28 11.6 19.3 0.46 10.9 19.3 1.4 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit DUF2203 PF09969.9 EPS30955.1 - 0.31 11.8 7.6 0.4 11.4 7.6 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) OmpH PF03938.14 EPS30955.1 - 0.4 11.0 19.9 0.44 10.9 19.9 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3435 PF11917.8 EPS30955.1 - 2.2 7.1 8.9 2.5 6.9 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) RRF PF01765.19 EPS30955.1 - 5 7.1 16.8 7 6.6 16.5 1.4 1 1 0 1 1 1 0 Ribosome recycling factor SAPS PF04499.15 EPS30955.1 - 5.1 5.8 9.6 5.9 5.6 9.6 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Arrestin_N PF00339.29 EPS30957.1 - 1.3e-10 41.5 0.1 2.5e-08 34.1 0.0 3.0 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain HNH_2 PF13391.6 EPS30959.1 - 0.0031 17.6 0.8 0.013 15.7 0.8 2.0 1 0 0 1 1 1 1 HNH endonuclease RNA_pol_Rpb2_6 PF00562.28 EPS30960.1 - 2.1e-123 412.2 0.1 3.5e-123 411.5 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EPS30960.1 - 4.5e-59 199.4 0.0 8.3e-59 198.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 EPS30960.1 - 1e-46 159.0 0.0 1.9e-46 158.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 EPS30960.1 - 1e-33 115.6 0.0 2.7e-33 114.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 EPS30960.1 - 2.3e-25 88.5 0.4 7.2e-25 87.0 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 EPS30960.1 - 4.1e-25 87.8 0.9 1.2e-24 86.3 0.9 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 EPS30960.1 - 1.8e-22 79.7 2.1 2.9e-22 79.0 0.4 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 MRNIP PF15749.5 EPS30960.1 - 0.5 11.1 1.3 0.61 10.8 0.0 1.8 2 0 0 2 2 2 0 MRN-interacting protein CTNNBL PF08216.11 EPS30961.1 - 3e-40 136.6 1.2 8.2e-40 135.2 0.3 2.3 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.23 EPS30961.1 - 0.0033 17.4 0.0 2.1 8.5 0.0 3.1 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Mo25 PF08569.11 EPS30961.1 - 0.0042 16.5 4.5 0.011 15.2 4.2 1.8 1 1 0 1 1 1 1 Mo25-like Drf_GBD PF06371.13 EPS30961.1 - 0.017 14.7 0.5 0.11 12.1 0.1 2.5 1 1 0 2 2 2 0 Diaphanous GTPase-binding Domain MMS19_C PF12460.8 EPS30961.1 - 0.031 13.4 2.5 0.93 8.5 0.3 2.5 2 0 0 2 2 2 0 RNAPII transcription regulator C-terminal SpecificRecomb PF10136.9 EPS30961.1 - 0.069 11.4 0.7 0.11 10.8 0.7 1.3 1 0 0 1 1 1 0 Site-specific recombinase Tom6 PF17112.5 EPS30962.1 - 0.00012 21.5 0.2 0.00016 21.1 0.2 1.2 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom6, fungal Tantalus PF15386.6 EPS30962.1 - 0.15 12.1 0.0 0.19 11.9 0.0 1.1 1 0 0 1 1 1 0 Drosophila Tantalus-like ING PF12998.7 EPS30963.1 - 2.7e-21 76.0 4.8 5.8e-21 75.0 4.8 1.6 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EPS30963.1 - 4.1e-05 23.4 9.8 7.4e-05 22.6 9.8 1.4 1 0 0 1 1 1 1 PHD-finger Cwf_Cwc_15 PF04889.12 EPS30963.1 - 0.0014 18.4 5.8 0.0026 17.6 5.8 1.5 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein zf-HC5HC2H PF13771.6 EPS30963.1 - 0.047 13.9 0.8 0.14 12.5 0.8 1.8 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_2 PF13831.6 EPS30963.1 - 0.32 10.6 4.6 0.68 9.5 4.6 1.6 1 0 0 1 1 1 0 PHD-finger TFIIA PF03153.13 EPS30963.1 - 2.9 7.8 15.5 6.6 6.6 15.5 1.6 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NAPRTase PF04095.16 EPS30964.1 - 1.1e-54 185.6 0.9 9.9e-29 100.6 1.2 2.1 1 1 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 EPS30964.1 - 3.5e-35 121.1 0.1 6.1e-35 120.3 0.1 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Fungal_trans PF04082.18 EPS30965.1 - 1e-21 77.2 1.5 1e-21 77.2 1.5 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain RNA_pol_Rpc34 PF05158.12 EPS30966.1 - 8.2e-113 377.2 0.0 9.1e-113 377.0 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.12 EPS30966.1 - 0.051 13.7 0.1 0.11 12.7 0.1 1.5 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC RPA_C PF08784.11 EPS30966.1 - 0.2 12.3 0.0 0.5 11.0 0.0 1.6 1 0 0 1 1 1 0 Replication protein A C terminal TPR_1 PF00515.28 EPS30967.1 - 9.4e-45 148.7 23.0 4.7e-06 26.2 0.0 8.7 9 0 0 9 9 9 8 Tetratricopeptide repeat STI1 PF17830.1 EPS30967.1 - 2.9e-36 123.2 9.0 1.6e-19 69.5 0.0 2.8 2 0 0 2 2 2 2 STI1 domain TPR_2 PF07719.17 EPS30967.1 - 8.3e-34 113.0 22.0 0.00046 20.1 0.1 9.5 8 1 1 9 9 9 6 Tetratricopeptide repeat TPR_8 PF13181.6 EPS30967.1 - 5.7e-21 72.9 24.3 0.00012 22.0 0.1 7.8 6 1 1 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.6 EPS30967.1 - 2.6e-20 72.5 17.2 8.7e-09 35.6 0.1 6.6 4 3 2 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 EPS30967.1 - 2e-17 62.6 27.9 1.1e-05 25.0 2.2 8.2 6 2 3 9 9 9 5 TPR repeat TPR_19 PF14559.6 EPS30967.1 - 8.3e-15 55.0 12.9 0.049 14.2 0.1 6.8 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.6 EPS30967.1 - 4e-14 53.0 17.8 0.00033 21.2 0.0 6.6 4 1 1 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 EPS30967.1 - 2.2e-11 43.6 13.2 1.3 10.0 0.3 8.7 4 3 5 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.6 EPS30967.1 - 2.6e-11 42.7 10.6 0.015 15.2 0.0 7.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_10 PF13374.6 EPS30967.1 - 1.8e-10 40.3 13.9 0.0022 17.8 0.1 6.8 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 EPS30967.1 - 2.1e-09 37.4 7.8 0.0057 16.8 0.1 5.4 2 2 4 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 EPS30967.1 - 3.5e-09 36.4 5.7 0.023 15.1 0.1 7.1 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 EPS30967.1 - 1.3e-06 28.7 16.6 0.78 10.5 0.0 8.5 8 0 0 8 8 8 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EPS30967.1 - 2.4e-05 24.3 2.2 0.14 12.3 0.0 4.9 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat RPN7 PF10602.9 EPS30967.1 - 0.004 16.9 10.9 0.43 10.3 0.2 4.9 3 3 2 6 6 6 2 26S proteasome subunit RPN7 SHNi-TPR PF10516.9 EPS30967.1 - 0.0098 15.3 4.0 12 5.5 0.0 4.6 4 0 0 4 4 4 0 SHNi-TPR TPR_20 PF14561.6 EPS30967.1 - 0.013 15.8 0.1 0.013 15.8 0.1 5.2 5 1 1 6 6 6 0 Tetratricopeptide repeat NARP1 PF12569.8 EPS30967.1 - 0.018 14.0 0.3 0.018 14.0 0.3 3.7 3 1 0 4 4 3 0 NMDA receptor-regulated protein 1 ANAPC3 PF12895.7 EPS30967.1 - 0.11 12.8 9.9 5.2 7.4 0.0 4.7 2 2 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Alkyl_sulf_dimr PF14863.6 EPS30967.1 - 0.22 12.0 0.0 0.22 12.0 0.0 4.1 3 3 1 4 4 4 0 Alkyl sulfatase dimerisation MIT PF04212.18 EPS30967.1 - 0.4 10.8 18.5 7.7 6.7 0.5 6.3 6 1 0 6 6 6 0 MIT (microtubule interacting and transport) domain C2 PF00168.30 EPS30968.1 - 4.7e-79 261.3 0.2 1.2e-22 80.1 0.0 5.5 5 0 0 5 5 5 5 C2 domain SMP_LBD PF17047.5 EPS30968.1 - 0.00029 20.3 0.0 0.00052 19.5 0.0 1.4 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain FKBP_C PF00254.28 EPS30968.1 - 0.15 12.4 0.0 0.52 10.7 0.0 1.9 1 0 0 1 1 1 0 FKBP-type peptidyl-prolyl cis-trans isomerase UDPGP PF01704.18 EPS30970.1 - 7.7e-192 637.5 0.1 8.9e-192 637.2 0.1 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase PilO PF04350.13 EPS30970.1 - 0.0049 17.0 0.1 0.017 15.3 0.0 1.8 2 0 0 2 2 2 1 Pilus assembly protein, PilO Fungal_trans PF04082.18 EPS30971.1 - 2.4e-18 66.1 1.5 4.5e-18 65.2 1.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS30971.1 - 1.2e-06 28.5 9.2 2.1e-06 27.7 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPS30972.1 - 8.6e-13 47.9 1.7 8.6e-13 47.9 1.7 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS30972.1 - 1.8e-08 34.4 11.2 1.8e-08 34.4 11.2 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SPX PF03105.19 EPS30972.1 - 2.3 8.0 10.2 0.24 11.3 1.0 2.2 2 0 0 2 2 2 0 SPX domain AT_hook PF02178.19 EPS30973.1 - 1e-06 27.9 24.3 0.037 13.9 2.9 4.1 3 0 0 3 3 3 3 AT hook motif FAM25 PF15825.5 EPS30975.1 - 0.44 10.9 3.6 1.5 9.2 0.3 2.2 1 1 1 2 2 2 0 FAM25 family MFS_1 PF07690.16 EPS30976.1 - 1.5e-21 76.8 36.9 1.8e-16 60.0 18.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS30976.1 - 6.2e-16 58.3 17.1 9.6e-16 57.7 16.7 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2755 PF10954.8 EPS30976.1 - 4 7.4 7.6 2.6 8.0 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2755) Glyco_hydro_28 PF00295.17 EPS30977.1 - 3.3e-30 105.3 6.5 4.1e-30 105.0 6.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.7 EPS30977.1 - 2.5e-06 27.5 15.1 5.2e-06 26.4 0.0 3.3 1 1 1 3 3 3 2 Pectate lyase superfamily protein Ribosomal_L7Ae PF01248.26 EPS30978.1 - 1.4e-27 95.3 0.0 1.6e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 EPS30978.1 - 7.5e-06 26.1 0.1 7.9e-06 26.0 0.1 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.6 EPS30978.1 - 2.8e-05 23.9 0.0 4.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain Metallophos PF00149.28 EPS30979.1 - 4.3e-10 40.4 0.0 5.3e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EPS30979.1 - 2e-06 28.1 0.0 2.4e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 EPS30979.1 - 0.2 11.0 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily HNH_2 PF13391.6 EPS30980.1 - 3.5e-12 46.3 0.0 6.6e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease Glyoxalase PF00903.25 EPS30981.1 - 6.9e-10 39.2 0.0 1.4e-09 38.2 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EPS30981.1 - 0.0014 18.9 0.0 0.0019 18.5 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 EPS30981.1 - 0.0095 15.9 0.0 0.025 14.5 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase-like domain Prim-Pol PF09250.11 EPS30981.1 - 0.06 13.7 0.0 0.49 10.7 0.0 1.9 1 1 1 2 2 2 0 Bifunctional DNA primase/polymerase, N-terminal Glyoxalase_3 PF13468.6 EPS30981.1 - 0.075 13.1 0.1 0.15 12.2 0.1 1.7 1 1 0 1 1 1 0 Glyoxalase-like domain BTB PF00651.31 EPS30982.1 - 0.012 15.9 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain MFS_1 PF07690.16 EPS30983.1 - 7.7e-32 110.6 30.3 7.7e-32 110.6 30.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3522 PF12036.8 EPS30983.1 - 0.046 14.0 0.0 0.046 14.0 0.0 3.2 3 2 0 3 3 3 0 Protein of unknown function (DUF3522) DUF202 PF02656.15 EPS30983.1 - 0.053 14.0 0.3 0.053 14.0 0.3 4.7 4 1 1 5 5 5 0 Domain of unknown function (DUF202) PSDC PF12588.8 EPS30984.1 - 4.1e-54 182.4 0.0 6.4e-54 181.7 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.15 EPS30984.1 - 7.6e-38 130.1 0.0 4.7e-37 127.5 0.0 1.9 2 0 0 2 2 2 1 Phosphatidylserine decarboxylase XPC-binding PF09280.11 EPS30984.1 - 0.1 12.4 0.4 0.54 10.0 0.4 2.1 2 0 0 2 2 2 0 XPC-binding domain Ank_4 PF13637.6 EPS30985.1 - 4.3e-16 59.1 0.3 0.023 15.3 0.0 5.9 6 1 0 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPS30985.1 - 1.8e-15 55.5 5.5 0.011 16.1 0.0 7.6 7 1 1 8 8 8 2 Ankyrin repeat Ank_2 PF12796.7 EPS30985.1 - 4.8e-14 52.7 0.0 0.0014 19.1 0.0 3.6 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EPS30985.1 - 1.2e-12 47.7 1.3 0.053 14.0 0.0 6.0 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 EPS30985.1 - 1.8e-08 34.5 1.0 0.36 11.2 0.0 5.3 5 2 1 6 6 6 3 Ankyrin repeats (many copies) DiS_P_DiS PF06750.13 EPS30985.1 - 0.075 13.2 0.0 3.7 7.7 0.0 2.4 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain S1-P1_nuclease PF02265.16 EPS30987.1 - 5.2e-68 229.6 0.0 6.1e-68 229.4 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease VWA_2 PF13519.6 EPS30988.1 - 0.0043 17.7 0.0 0.017 15.7 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain UBA_4 PF14555.6 EPS30988.1 - 0.017 14.9 2.9 0.096 12.5 0.2 2.5 2 0 0 2 2 2 0 UBA-like domain FAD_binding_3 PF01494.19 EPS30989.1 - 7.8e-30 104.3 0.1 2e-29 102.9 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 EPS30989.1 - 0.00017 20.8 1.3 0.035 13.2 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.6 EPS30989.1 - 0.00042 20.5 0.1 0.0011 19.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EPS30989.1 - 0.0023 17.6 0.0 0.0041 16.8 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPS30989.1 - 0.093 11.9 1.2 1.4 8.1 0.3 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EPS30989.1 - 0.23 10.7 0.3 5 6.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF3148 PF11347.8 EPS30990.1 - 0.2 11.5 0.0 0.41 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3148) Metallophos PF00149.28 EPS30992.1 - 3.3e-15 57.1 0.5 4.5e-15 56.7 0.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase BTB PF00651.31 EPS30993.1 - 5.1e-06 26.7 0.0 1.1e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Orthoreo_P10 PF07204.11 EPS30995.1 - 0.0097 15.9 11.1 0.56 10.2 0.3 5.0 4 1 0 4 4 4 3 Orthoreovirus membrane fusion protein p10 Acetyltransf_2 PF00797.17 EPS30997.1 - 2.1e-43 148.8 0.2 2.9e-42 145.1 0.2 2.1 1 1 0 1 1 1 1 N-acetyltransferase Transglut_core PF01841.19 EPS30997.1 - 2.2e-05 24.9 0.1 4.7e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily FAD_binding_3 PF01494.19 EPS30998.1 - 1.2e-21 77.4 0.3 5.3e-21 75.2 0.3 2.0 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 EPS30998.1 - 0.00034 20.1 0.2 0.09 12.1 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EPS30998.1 - 0.0012 19.1 0.4 0.0033 17.6 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain OAD_beta PF03977.13 EPS30998.1 - 0.0033 16.5 0.1 0.0051 15.9 0.1 1.2 1 0 0 1 1 1 1 Na+-transporting oxaloacetate decarboxylase beta subunit Pyr_redox_2 PF07992.14 EPS30998.1 - 0.0094 15.2 1.4 0.15 11.2 0.6 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EPS30998.1 - 0.015 14.9 1.1 0.063 12.8 0.5 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase SE PF08491.10 EPS30998.1 - 0.019 14.1 0.0 0.024 13.7 0.0 1.3 1 1 0 1 1 1 0 Squalene epoxidase FAD_binding_2 PF00890.24 EPS30998.1 - 0.027 13.6 0.6 0.044 12.9 0.6 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.6 EPS30998.1 - 0.11 11.7 0.3 3.6 6.7 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Cren7 PF11520.8 EPS30998.1 - 0.18 11.8 0.0 2.1 8.3 0.0 2.2 1 1 1 2 2 2 0 Chromatin protein Cren7 Myb_CC_LHEQLE PF14379.6 EPS30998.1 - 0.19 11.4 1.3 0.48 10.2 1.3 1.7 1 0 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif HI0933_like PF03486.14 EPS30998.1 - 0.29 9.8 2.7 0.9 8.2 1.2 2.0 2 0 0 2 2 2 0 HI0933-like protein Acetyltransf_10 PF13673.7 EPS30999.1 - 1.5e-12 47.5 0.0 2e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPS30999.1 - 1.5e-07 31.7 0.0 1.8e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EPS30999.1 - 2.2e-07 31.2 0.0 3.4e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EPS30999.1 - 0.16 12.1 0.0 0.19 11.8 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NAD_binding_10 PF13460.6 EPS31000.1 - 8.2e-09 35.6 0.0 1.1e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EPS31000.1 - 5.4e-06 26.1 0.0 2.4e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.21 EPS31000.1 - 0.00092 18.7 0.0 0.0075 15.8 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family APH PF01636.23 EPS31004.1 - 7.3e-10 39.2 0.0 1.8e-09 37.9 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPS31004.1 - 1.5e-07 31.2 0.0 3e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.25 EPS31004.1 - 0.15 11.4 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain DUF3040 PF11239.8 EPS31005.1 - 0.0024 18.1 0.0 0.0043 17.3 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3040) DUF2207 PF09972.9 EPS31005.1 - 0.019 13.8 0.1 0.02 13.7 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TarH PF02203.15 EPS31005.1 - 0.054 13.4 0.1 0.081 12.9 0.1 1.2 1 0 0 1 1 1 0 Tar ligand binding domain homologue MgtE PF01769.16 EPS31005.1 - 0.061 13.7 0.1 0.081 13.3 0.1 1.2 1 0 0 1 1 1 0 Divalent cation transporter DUF3341 PF11821.8 EPS31005.1 - 0.071 12.8 0.0 0.077 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) DUF3671 PF12420.8 EPS31005.1 - 0.16 12.0 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function Amidase PF01425.21 EPS31006.1 - 3.6e-86 289.9 0.0 5e-86 289.5 0.0 1.2 1 0 0 1 1 1 1 Amidase MFS_1 PF07690.16 EPS31007.1 - 1.1e-10 41.0 22.4 1.1e-10 41.0 22.4 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily TMEM208_SND2 PF05620.11 EPS31007.1 - 0.13 12.0 3.3 0.091 12.5 0.4 2.3 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 Fungal_trans_2 PF11951.8 EPS31008.1 - 1.7e-09 37.0 2.1 2.5e-08 33.2 0.3 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS31008.1 - 2.1e-06 27.8 8.5 3.9e-06 26.9 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.18 EPS31009.1 - 1.3e-07 31.6 11.4 2.4e-07 30.8 11.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPS31009.1 - 0.0033 16.5 1.0 0.0041 16.2 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain FYVE PF01363.21 EPS31010.1 - 1.4e-20 73.2 1.0 1.4e-20 73.2 1.0 3.1 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 EPS31010.1 - 1.1e-07 32.0 3.8 1.1e-07 32.0 3.8 3.4 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 EPS31010.1 - 4.5e-05 23.2 3.7 4.5e-05 23.2 3.7 3.8 3 1 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EPS31010.1 - 0.00039 20.1 3.6 0.00039 20.1 3.6 2.5 3 0 0 3 3 2 1 RING-like zinc finger zf-rbx1 PF12678.7 EPS31010.1 - 0.0025 18.1 3.0 0.0025 18.1 3.0 3.2 3 1 1 4 4 3 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EPS31010.1 - 0.0026 17.6 3.7 0.0026 17.6 3.7 3.5 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPS31010.1 - 0.0052 16.8 3.1 0.0052 16.8 3.1 3.7 3 0 0 3 3 3 1 RING-type zinc-finger Rad50_zn_hook PF04423.14 EPS31010.1 - 0.013 15.3 0.4 1.5 8.7 0.1 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif FYVE_2 PF02318.16 EPS31010.1 - 0.046 13.9 0.3 0.046 13.9 0.3 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger TF_Zn_Ribbon PF08271.12 EPS31010.1 - 0.64 9.6 8.4 1.6 8.3 4.6 2.7 2 0 0 2 2 2 0 TFIIB zinc-binding DZR PF12773.7 EPS31010.1 - 1.4 9.0 9.4 5.2 7.2 4.1 2.9 3 0 0 3 3 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 EPS31010.1 - 5.4 7.2 9.1 74 3.6 5.3 3.3 2 1 0 2 2 2 0 Zinc ribbon domain FANCL_C PF11793.8 EPS31010.1 - 8.1 6.7 13.3 0.043 14.0 3.6 2.1 2 0 0 2 2 1 0 FANCL C-terminal domain TRP PF06011.12 EPS31011.1 - 2.9e-37 128.4 20.3 1.3e-34 119.7 20.3 2.2 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EPS31011.1 - 9.3e-20 71.4 0.2 1.4e-19 70.8 0.2 1.2 1 0 0 1 1 1 1 ML-like domain Importin_rep_2 PF18786.1 EPS31011.1 - 0.26 11.1 0.8 0.53 10.2 0.8 1.4 1 0 0 1 1 1 0 Importin 13 repeat DUF3770 PF12603.8 EPS31013.1 - 0.088 12.3 0.6 0.29 10.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3770) Cys_Met_Meta_PP PF01053.20 EPS31014.1 - 1.5e-61 208.1 0.0 3.2e-61 207.0 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EPS31014.1 - 2.4e-05 23.7 0.0 4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EPS31014.1 - 0.0059 15.6 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EPS31014.1 - 0.2 10.9 0.0 9 5.5 0.0 2.7 3 0 0 3 3 3 0 DegT/DnrJ/EryC1/StrS aminotransferase family MFS_1 PF07690.16 EPS31015.1 - 8.8e-37 126.8 28.8 8.8e-37 126.8 28.8 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MWFE PF15879.5 EPS31015.1 - 0.05 13.8 1.1 0.13 12.5 0.0 2.3 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit ThiS PF02597.20 EPS31016.1 - 6.9e-08 33.0 0.0 7.8e-08 32.8 0.0 1.0 1 0 0 1 1 1 1 ThiS family MARVEL PF01284.23 EPS31017.1 - 0.015 15.4 11.6 0.021 14.8 11.6 1.3 1 0 0 1 1 1 0 Membrane-associating domain FAD_binding_4 PF01565.23 EPS31019.1 - 2.9e-20 72.4 1.2 4.6e-20 71.8 1.2 1.3 1 0 0 1 1 1 1 FAD binding domain DUF2922 PF11148.8 EPS31019.1 - 0.04 13.6 0.1 0.095 12.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) RNB PF00773.19 EPS31020.1 - 3e-51 174.7 0.0 1.7e-48 165.6 0.0 2.8 2 1 0 2 2 2 1 RNB domain AMP-binding PF00501.28 EPS31021.1 - 6e-67 226.1 0.0 1e-66 225.3 0.0 1.3 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EPS31021.1 - 5.4e-13 49.7 0.0 1.5e-12 48.3 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain BolA PF01722.18 EPS31022.1 - 1e-30 105.8 3.4 1.3e-30 105.5 3.4 1.1 1 0 0 1 1 1 1 BolA-like protein SNARE PF05739.19 EPS31023.1 - 1.9e-11 43.8 1.5 6.9e-11 42.0 0.3 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 EPS31023.1 - 6.9e-10 38.9 9.5 6.9e-10 38.9 9.5 1.9 2 1 0 2 2 2 1 Syntaxin Use1 PF09753.9 EPS31023.1 - 0.0013 18.5 11.7 0.015 15.1 11.7 2.0 1 1 0 1 1 1 1 Membrane fusion protein Use1 Bac_export_3 PF01313.19 EPS31023.1 - 0.091 12.7 0.2 0.091 12.7 0.2 2.6 3 0 0 3 3 3 0 Bacterial export proteins, family 3 GTP-bdg_M PF16360.5 EPS31023.1 - 0.18 12.4 0.3 0.18 12.4 0.3 3.2 3 2 0 3 3 3 0 GTP-binding GTPase Middle Region HisKA_3 PF07730.13 EPS31023.1 - 1.3 9.5 7.3 5.6 7.6 0.5 3.0 2 1 1 3 3 3 0 Histidine kinase COG5 PF10392.9 EPS31023.1 - 1.6 8.9 11.0 0.24 11.6 2.4 3.0 3 1 0 3 3 3 0 Golgi transport complex subunit 5 CD225 PF04505.12 EPS31023.1 - 2.7 8.2 6.3 0.16 12.1 0.9 1.7 2 0 0 2 2 2 0 Interferon-induced transmembrane protein PTR2 PF00854.21 EPS31024.1 - 9.5e-93 311.1 8.5 1.4e-92 310.5 8.5 1.3 1 0 0 1 1 1 1 POT family p450 PF00067.22 EPS31026.1 - 5.6e-41 140.8 0.0 7.1e-41 140.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1707 PF08044.11 EPS31026.1 - 0.0058 16.7 0.1 0.012 15.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1707) IF4E PF01652.18 EPS31027.1 - 2.2e-53 180.3 0.1 2.7e-53 180.0 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Mpv17_PMP22 PF04117.12 EPS31028.1 - 2.2e-23 82.3 1.1 2.2e-23 82.3 1.1 1.6 2 0 0 2 2 2 1 Mpv17 / PMP22 family Ribosomal_S5 PF00333.20 EPS31029.1 - 1e-25 89.5 1.5 2.5e-25 88.2 0.8 2.0 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 EPS31029.1 - 6.1e-23 80.1 0.0 1.1e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.6 EPS31029.1 - 0.68 10.5 11.9 1.5 9.4 11.9 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 FXMRP1_C_core PF12235.8 EPS31029.1 - 5.2 7.7 9.2 9.4 6.9 9.2 1.4 1 0 0 1 1 1 0 Fragile X-related 1 protein core C terminal Bac_rhodopsin PF01036.18 EPS31032.1 - 2.2e-30 105.9 13.7 2.7e-30 105.6 13.7 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein TIC20 PF16166.5 EPS31032.1 - 0.0062 16.3 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 Chloroplast import apparatus Tic20-like DUF485 PF04341.12 EPS31032.1 - 6.4 6.8 9.6 1.2 9.2 0.9 2.8 2 1 0 2 2 2 0 Protein of unknown function, DUF485 tRNA-synt_1 PF00133.22 EPS31033.1 - 1.8e-166 554.9 0.0 2.4e-166 554.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EPS31033.1 - 3.5e-20 72.1 0.0 4.8e-13 48.6 0.0 3.5 3 1 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EPS31033.1 - 4.2e-20 72.3 0.3 8.1e-20 71.3 0.3 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA zf-FPG_IleRS PF06827.14 EPS31033.1 - 0.0038 17.1 1.6 0.066 13.1 0.3 2.4 2 0 0 2 2 2 1 Zinc finger found in FPG and IleRS tRNA-synt_1e PF01406.19 EPS31033.1 - 0.037 13.4 0.0 3.9 6.7 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.6 EPS31033.1 - 0.041 13.4 0.0 0.071 12.6 0.0 1.3 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 UPF0183 PF03676.14 EPS31034.1 - 6.2e-52 177.2 0.0 1.3e-34 120.2 0.0 2.9 2 1 0 2 2 2 2 Uncharacterised protein family (UPF0183) Kinesin PF00225.23 EPS31035.1 - 1.7e-111 372.4 2.0 1.7e-111 372.4 2.0 2.1 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EPS31035.1 - 3.5e-24 85.5 0.1 3.5e-24 85.5 0.1 2.9 3 0 0 3 3 3 1 Microtubule binding Microtub_bind PF13931.6 EPS31035.1 - 5e-07 30.2 0.1 5e-07 30.2 0.1 4.5 4 1 0 4 4 4 1 Kinesin-associated microtubule-binding Baculo_PEP_C PF04513.12 EPS31035.1 - 0.054 13.5 26.8 0.078 13.0 0.0 5.9 3 2 2 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sacchrp_dh_C PF16653.5 EPS31035.1 - 0.072 13.2 0.2 0.16 12.1 0.2 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase C-terminal domain Filament PF00038.21 EPS31035.1 - 1.1 8.8 56.7 3.8 7.0 9.3 3.6 2 1 0 3 3 3 0 Intermediate filament protein DUF1117 PF06547.12 EPS31035.1 - 1.5 9.4 4.2 53 4.4 0.5 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1117) ECSIT_C PF14784.6 EPS31035.1 - 2 8.8 5.4 0.59 10.5 0.6 2.7 2 0 0 2 2 2 0 C-terminal domain of the ECSIT protein DUF3138 PF11336.8 EPS31035.1 - 3.1 6.3 9.7 0.089 11.4 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) zf-ANAPC11 PF12861.7 EPS31037.1 - 3.4e-46 155.2 11.1 4e-46 155.0 11.1 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EPS31037.1 - 2.2e-21 75.9 10.4 2.8e-21 75.5 10.4 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EPS31037.1 - 6.9e-09 35.9 15.5 1.7e-07 31.4 15.2 2.5 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EPS31037.1 - 3.3e-05 23.6 4.4 3.3e-05 23.6 4.4 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPS31037.1 - 4.1e-05 23.5 9.1 0.0001 22.3 4.3 2.4 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.6 EPS31037.1 - 0.00057 19.6 11.2 0.035 13.9 8.1 2.7 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 EPS31037.1 - 0.0008 19.2 13.0 0.0034 17.2 13.0 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EPS31037.1 - 0.00083 19.2 12.3 0.046 13.6 12.5 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EPS31037.1 - 0.0017 18.4 1.5 0.0017 18.4 1.5 2.4 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 EPS31037.1 - 0.0032 17.6 15.7 0.096 12.9 15.7 3.2 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_5 PF14634.6 EPS31037.1 - 0.01 15.8 15.1 0.082 12.9 15.3 2.5 1 1 1 2 2 2 0 zinc-RING finger domain Zn_ribbon_17 PF17120.5 EPS31037.1 - 0.046 13.3 13.1 0.073 12.7 10.8 2.1 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 EPS31037.1 - 0.11 12.4 13.6 8.1 6.4 13.9 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Rad50_zn_hook PF04423.14 EPS31037.1 - 0.14 12.0 1.6 1.9 8.4 0.0 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-Nse PF11789.8 EPS31037.1 - 0.29 11.0 4.1 0.57 10.1 4.1 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit PHD PF00628.29 EPS31037.1 - 0.7 9.8 13.4 3.6 7.6 13.4 2.1 1 1 0 1 1 1 0 PHD-finger zf-Di19 PF05605.12 EPS31037.1 - 0.85 10.0 11.4 39 4.7 7.7 3.0 1 1 1 2 2 1 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_11 PF17123.5 EPS31037.1 - 0.88 9.4 13.4 1.1 9.1 9.9 2.7 2 1 0 2 2 2 0 RING-like zinc finger zf-RING-like PF08746.11 EPS31037.1 - 1 9.8 12.0 7.2 7.0 12.1 2.3 1 1 0 1 1 1 0 RING-like domain Opy2 PF09463.10 EPS31037.1 - 1.3 9.4 8.1 4.6 7.6 4.8 2.6 2 1 1 3 3 3 0 Opy2 protein TerY_C PF15616.6 EPS31037.1 - 1.3 9.1 7.5 1.9 8.6 7.5 1.4 1 1 0 1 1 1 0 TerY-C metal binding domain zf-C2H2_9 PF16293.5 EPS31037.1 - 1.6 8.6 7.8 4.5 7.2 0.1 3.2 2 1 0 2 2 2 0 C2H2 type zinc-finger (1 copy) RINGv PF12906.7 EPS31037.1 - 2.2 8.5 13.6 2.6 8.2 11.0 2.4 1 1 1 2 2 2 0 RING-variant domain Zf_RING PF16744.5 EPS31037.1 - 3.8 7.7 9.3 1.4e+02 2.7 9.3 2.3 1 1 0 1 1 1 0 KIAA1045 RING finger Pellino PF04710.14 EPS31037.1 - 5.4 5.6 6.9 0.78 8.3 1.8 1.8 1 1 0 2 2 2 0 Pellino zf-HIT PF04438.16 EPS31037.1 - 7 6.6 9.7 3.8 7.5 4.9 2.4 2 1 0 2 2 2 0 HIT zinc finger Prok-RING_1 PF14446.6 EPS31037.1 - 8.2 6.4 15.8 11 6.0 0.1 3.1 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 Rhodanese PF00581.20 EPS31038.1 - 5.1e-16 59.1 0.0 6e-09 36.4 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain PIN_4 PF13638.6 EPS31039.1 - 2.2e-05 24.7 0.0 0.0039 17.5 0.0 2.4 1 1 0 1 1 1 1 PIN domain RPEL PF02755.15 EPS31041.1 - 1.3e-26 91.5 13.0 2.2e-09 36.7 1.0 3.6 3 0 0 3 3 3 3 RPEL repeat Rotamase_3 PF13616.6 EPS31041.1 - 0.045 14.3 0.3 0.62 10.6 0.1 2.0 1 1 1 2 2 2 0 PPIC-type PPIASE domain Translin PF01997.16 EPS31042.1 - 1.6e-70 237.3 0.2 1.9e-70 237.0 0.2 1.0 1 0 0 1 1 1 1 Translin family ADH_N PF08240.12 EPS31043.1 - 1.4e-23 82.9 0.9 2.3e-23 82.2 0.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPS31043.1 - 9.7e-22 77.3 0.0 1.4e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPS31043.1 - 7.7e-05 23.8 0.0 0.00012 23.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Fer4_2 PF12797.7 EPS31043.1 - 0.99 9.6 4.1 0.48 10.6 0.9 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain Mannosidase_ig PF17786.1 EPS31044.1 - 7.8e-18 64.9 0.1 2.6e-17 63.2 0.0 2.0 2 0 0 2 2 2 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 EPS31044.1 - 4.1e-14 53.2 0.0 9.7e-14 52.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.17 EPS31044.1 - 0.0059 15.8 0.1 0.015 14.4 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Ig_mannosidase PF17753.1 EPS31044.1 - 0.006 16.3 0.0 0.04 13.7 0.0 2.4 2 0 0 2 2 2 1 Ig-fold domain Fungal_trans PF04082.18 EPS31045.1 - 5.9e-18 64.8 0.1 1e-17 64.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS31045.1 - 3.9e-06 26.9 14.2 7.3e-06 26.0 14.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mannosyl_trans PF05007.13 EPS31046.1 - 7.2e-76 255.5 12.8 9.4e-76 255.1 12.8 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 EPS31046.1 - 1.1e-09 37.8 17.0 3.5e-09 36.2 17.0 1.7 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U GT87 PF09594.10 EPS31046.1 - 0.0014 18.4 31.1 0.0014 18.4 31.1 3.0 2 1 0 3 3 3 1 Glycosyltransferase family 87 DUF4307 PF14155.6 EPS31046.1 - 0.47 10.3 1.5 1.1 9.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4307) TM_helix PF05552.12 EPS31046.1 - 3.2 7.8 11.1 6.3 6.9 0.5 3.9 3 0 0 3 3 3 0 Conserved TM helix NIBRIN_BRCT_II PF16508.5 EPS31047.1 - 4.9e-36 123.6 0.0 1.6e-35 122.0 0.0 1.9 2 0 0 2 2 2 1 Second BRCT domain on Nijmegen syndrome breakage protein FHA PF00498.26 EPS31047.1 - 0.0047 17.3 0.1 0.011 16.1 0.1 1.6 1 0 0 1 1 1 1 FHA domain RTT107_BRCT_5 PF16770.5 EPS31047.1 - 0.096 12.6 0.1 0.34 10.8 0.0 1.9 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain IMS PF00817.20 EPS31048.1 - 1e-42 145.7 0.4 1.9e-42 144.8 0.4 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 EPS31048.1 - 9.2e-16 58.6 0.1 3.5e-15 56.7 0.1 2.0 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 EPS31048.1 - 2.5e-05 24.3 0.0 7.2e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif PsiA PF06952.11 EPS31049.1 - 0.062 12.5 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 PsiA protein PhyH PF05721.13 EPS31050.1 - 1.9e-05 25.0 0.4 8.2e-05 22.9 0.4 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 EPS31050.1 - 0.0002 20.2 0.0 0.88 8.3 0.1 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_3 PF13640.6 EPS31050.1 - 0.041 14.8 0.0 0.089 13.7 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 EPS31050.1 - 0.058 13.8 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase FAD_binding_3 PF01494.19 EPS31051.1 - 2.9e-19 69.5 2.6 1.2e-18 67.5 2.6 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EPS31051.1 - 4e-08 32.8 2.3 0.00031 20.1 0.3 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EPS31051.1 - 8.9e-08 32.1 3.1 3e-05 23.8 1.0 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EPS31051.1 - 2.5e-07 29.9 0.2 0.016 14.0 0.1 2.8 3 0 0 3 3 3 2 Tryptophan halogenase NAD_binding_8 PF13450.6 EPS31051.1 - 1.7e-05 25.0 0.1 4.1e-05 23.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EPS31051.1 - 2.2e-05 23.7 0.5 6.1e-05 22.3 0.5 1.7 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EPS31051.1 - 0.00039 19.6 0.0 0.00054 19.2 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EPS31051.1 - 0.0012 18.2 0.2 0.0081 15.4 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EPS31051.1 - 0.0016 17.8 0.9 0.1 11.9 0.1 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 EPS31051.1 - 0.002 16.9 1.1 0.003 16.3 0.3 1.6 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 EPS31051.1 - 0.0025 17.2 0.1 0.007 15.7 0.0 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 EPS31051.1 - 0.0036 16.4 4.4 0.0089 15.1 2.9 2.4 2 1 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.27 EPS31051.1 - 0.0048 17.4 0.6 0.011 16.3 0.2 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EPS31051.1 - 0.011 15.7 3.0 0.73 9.8 0.1 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding SE PF08491.10 EPS31051.1 - 0.026 13.6 0.0 1.5 7.8 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Thi4 PF01946.17 EPS31051.1 - 0.057 12.6 0.2 0.16 11.2 0.1 1.7 2 0 0 2 2 2 0 Thi4 family CzcE PF16986.5 EPS31051.1 - 0.15 12.4 0.1 0.53 10.6 0.1 1.9 1 0 0 1 1 1 0 Heavy-metal resistance protein CzcE FAD_oxidored PF12831.7 EPS31051.1 - 0.21 10.9 3.5 0.28 10.5 3.5 1.4 1 1 0 1 1 1 0 FAD dependent oxidoreductase Fungal_trans PF04082.18 EPS31052.1 - 1.1e-08 34.4 1.0 1.9e-08 33.7 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EPS31052.1 - 1.4e-08 34.8 10.8 0.00048 20.4 0.2 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EPS31052.1 - 7.5e-07 29.3 6.2 0.00053 20.3 0.4 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EPS31052.1 - 1.3e-06 28.7 9.3 0.0064 17.2 0.2 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 EPS31052.1 - 0.00011 22.5 2.0 0.084 13.3 0.0 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EPS31052.1 - 0.00013 22.2 2.4 0.28 11.5 0.0 2.8 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding Zn_clus PF00172.18 EPS31052.1 - 0.0018 18.3 11.0 0.0047 17.0 11.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-Di19 PF05605.12 EPS31052.1 - 0.0021 18.3 5.0 0.0048 17.2 5.0 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.6 EPS31052.1 - 0.0098 15.8 5.7 0.058 13.3 0.2 2.8 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 EPS31052.1 - 0.61 10.2 6.5 1.2 9.2 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger DUF2225 PF09986.9 EPS31052.1 - 0.76 9.5 2.3 0.68 9.6 0.6 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) MFS_1 PF07690.16 EPS31053.1 - 1.1e-22 80.5 34.0 1.1e-22 80.5 34.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily GATase PF00117.28 EPS31056.1 - 1e-36 126.5 0.0 1.6e-36 125.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.22 EPS31056.1 - 6.5e-35 119.1 0.0 1.2e-34 118.2 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.17 EPS31056.1 - 2.5e-07 30.1 0.0 9e-05 21.7 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 EPS31056.1 - 2.2e-06 27.6 0.0 4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.16 EPS31056.1 - 0.0038 16.1 0.0 0.0078 15.0 0.0 1.4 1 0 0 1 1 1 1 tRNA methyl transferase QueC PF06508.13 EPS31056.1 - 0.057 12.9 0.0 0.14 11.6 0.0 1.6 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC DUF2732 PF10809.8 EPS31056.1 - 0.17 11.8 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2732) MARVEL PF01284.23 EPS31057.1 - 5.5e-08 33.0 16.1 7.8e-08 32.5 16.1 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF2678 PF10856.8 EPS31057.1 - 0.093 12.7 0.4 0.093 12.7 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) DUF2569 PF10754.9 EPS31057.1 - 0.71 10.3 10.2 1.6 9.2 8.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) Trep_Strep PF09605.10 EPS31057.1 - 4.2 7.3 15.4 0.2 11.6 9.9 1.5 2 0 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) MotB_plug PF13677.6 EPS31057.1 - 5.5 6.7 6.3 1.4 8.6 1.3 2.3 2 1 0 2 2 2 0 Membrane MotB of proton-channel complex MotA/MotB DnaJ-X PF14308.6 EPS31058.1 - 4.3e-76 255.0 6.9 4.3e-76 255.0 6.9 3.3 4 1 0 4 4 4 1 X-domain of DnaJ-containing DnaJ PF00226.31 EPS31058.1 - 2.8e-25 88.2 0.2 7.5e-25 86.8 0.2 1.8 1 0 0 1 1 1 1 DnaJ domain OrfB_IS605 PF01385.19 EPS31058.1 - 5.4 7.3 7.0 0.81 9.9 2.5 1.9 2 0 0 2 2 2 0 Probable transposase SQS_PSY PF00494.19 EPS31059.1 - 6.5e-37 127.4 0.0 8.3e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Peptidase_A4 PF01828.17 EPS31060.1 - 4.3e-67 225.6 10.9 5.3e-67 225.3 10.9 1.1 1 0 0 1 1 1 1 Peptidase A4 family FAD_binding_4 PF01565.23 EPS31061.1 - 2.7e-28 98.4 0.4 4.1e-28 97.9 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EPS31061.1 - 0.0071 16.4 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like TauD PF02668.16 EPS31063.1 - 5.4e-52 177.2 1.0 6.3e-52 177.0 1.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family AA_permease PF00324.21 EPS31064.1 - 2.9e-115 385.6 41.6 3.5e-115 385.4 41.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EPS31064.1 - 3.9e-29 101.7 44.4 4.8e-29 101.4 44.4 1.0 1 0 0 1 1 1 1 Amino acid permease ADH_N PF08240.12 EPS31066.1 - 3.4e-28 97.7 1.3 3.4e-28 97.7 1.3 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPS31066.1 - 2.3e-22 79.4 0.0 4.1e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPS31066.1 - 5.9e-08 33.8 0.0 1.4e-07 32.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EPS31066.1 - 1.5e-05 24.4 0.1 2.9e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Glu_dehyd_C PF16912.5 EPS31066.1 - 9e-05 22.1 0.2 0.00023 20.7 0.2 1.6 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus Pyr_redox_2 PF07992.14 EPS31066.1 - 0.03 13.6 0.1 0.063 12.5 0.1 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_25 PF13649.6 EPS31066.1 - 0.1 13.3 0.1 0.2 12.4 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain ADH_N_assoc PF13823.6 EPS31066.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated AA_permease_2 PF13520.6 EPS31068.1 - 2.3e-48 165.1 53.1 2.9e-48 164.8 53.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPS31068.1 - 3.4e-30 105.1 45.5 4.7e-30 104.6 45.5 1.0 1 0 0 1 1 1 1 Amino acid permease GAPT PF11770.8 EPS31068.1 - 0.035 14.0 0.4 0.075 12.9 0.4 1.5 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) uDENN PF03456.18 EPS31068.1 - 0.14 12.9 0.1 0.55 11.0 0.0 1.9 2 0 0 2 2 2 0 uDENN domain DUF3810 PF12725.7 EPS31068.1 - 0.35 10.2 0.0 0.35 10.2 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3810) CTV_P6 PF06706.11 EPS31068.1 - 3 7.6 8.5 0.47 10.2 0.1 3.4 3 0 0 3 3 3 0 Citrus tristeza virus 6-kDa protein Cellulase PF00150.18 EPS31069.1 - 2.7e-19 69.7 0.7 4e-19 69.1 0.7 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 EPS31069.1 - 1.2e-12 47.6 17.1 3.8e-12 45.9 17.1 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_2_C PF02836.17 EPS31069.1 - 7.7e-05 21.9 0.1 0.00014 21.1 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.15 EPS31069.1 - 0.017 14.5 0.1 0.032 13.6 0.1 1.4 1 0 0 1 1 1 0 Beta-galactosidase Mucin PF01456.17 EPS31069.1 - 1.5 8.8 30.3 0.057 13.4 24.4 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein Sugar_tr PF00083.24 EPS31071.1 - 4.2e-146 487.4 24.0 4.9e-146 487.2 24.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS31071.1 - 2.2e-23 82.8 33.7 1.5e-16 60.3 10.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_75 PF07335.11 EPS31072.1 - 7.3e-64 214.9 0.7 1e-63 214.5 0.7 1.2 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 AMP-binding PF00501.28 EPS31073.1 - 1.2e-92 310.8 0.1 1.6e-92 310.3 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EPS31073.1 - 4.1e-14 53.3 0.0 8.3e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PTPLA PF04387.14 EPS31074.1 - 7.4e-47 159.1 12.7 1.1e-46 158.6 12.7 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA DUF2183 PF09949.9 EPS31075.1 - 1.6e-21 76.5 0.1 3e-21 75.6 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Methyltransf_23 PF13489.6 EPS31076.1 - 4.4e-18 65.7 0.0 5.7e-18 65.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS31076.1 - 2e-16 60.4 0.0 5.3e-16 59.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPS31076.1 - 2.2e-16 60.3 0.0 6.4e-16 58.8 0.0 1.8 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPS31076.1 - 1.4e-15 57.9 0.0 2.9e-15 56.8 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPS31076.1 - 4.6e-15 55.7 0.0 7.5e-15 55.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPS31076.1 - 3.5e-07 29.8 0.0 1.3e-06 27.9 0.0 1.8 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 EPS31076.1 - 8.6e-06 25.6 0.0 1.8e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 Lysine methyltransferase NodS PF05401.11 EPS31076.1 - 1.5e-05 24.7 0.0 0.00019 21.1 0.0 2.0 2 0 0 2 2 2 1 Nodulation protein S (NodS) RrnaAD PF00398.20 EPS31076.1 - 0.00012 21.3 0.0 0.00018 20.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PrmA PF06325.13 EPS31076.1 - 0.00073 19.0 0.0 0.001 18.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DREV PF05219.12 EPS31076.1 - 0.0033 16.5 0.0 0.0075 15.4 0.0 1.5 2 0 0 2 2 2 1 DREV methyltransferase PCMT PF01135.19 EPS31076.1 - 0.004 16.9 0.0 0.011 15.5 0.0 1.7 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 EPS31076.1 - 0.027 14.0 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 EPS31076.1 - 0.041 13.3 0.0 0.62 9.5 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase Pox_MCEL PF03291.16 EPS31076.1 - 0.074 12.1 0.0 0.12 11.5 0.0 1.4 1 1 0 1 1 1 0 mRNA capping enzyme TehB PF03848.14 EPS31076.1 - 0.092 12.1 0.0 2.4 7.6 0.0 2.4 3 0 0 3 3 3 0 Tellurite resistance protein TehB Methyltransf_18 PF12847.7 EPS31076.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.12 EPS31076.1 - 0.14 11.9 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_9 PF08003.11 EPS31076.1 - 0.14 11.0 0.0 0.42 9.5 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) Peptidase_S10 PF00450.22 EPS31077.1 - 1.9e-104 350.4 8.8 2.3e-104 350.1 8.8 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF4246 PF14033.6 EPS31078.1 - 7.1e-127 424.3 0.4 1.1e-126 423.7 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) NPP1 PF05630.11 EPS31080.1 - 3.6e-61 206.7 0.2 4.9e-61 206.3 0.2 1.2 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Myb_DNA-bind_6 PF13921.6 EPS31083.1 - 5e-05 23.5 0.1 0.00011 22.4 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EPS31083.1 - 0.0027 17.9 0.1 0.005 17.0 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain AAA PF00004.29 EPS31085.1 - 1.4e-13 51.4 0.0 2e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EPS31085.1 - 0.0041 17.1 0.1 0.0072 16.3 0.1 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EPS31085.1 - 0.087 13.2 0.6 0.27 11.6 0.6 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 EPS31085.1 - 0.099 12.3 0.5 0.27 10.9 0.5 1.6 1 1 0 1 1 1 0 AAA domain Ank_2 PF12796.7 EPS31086.1 - 2.7e-13 50.3 0.0 5.2e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EPS31086.1 - 4e-13 49.3 0.0 1.3e-06 28.5 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPS31086.1 - 6.8e-12 44.5 0.0 0.00027 21.1 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 EPS31086.1 - 2.3e-11 43.6 0.0 0.0002 21.6 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EPS31086.1 - 8.9e-11 42.1 0.0 1.6e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) GATase_7 PF13537.6 EPS31086.1 - 0.012 15.5 0.0 0.47 10.4 0.0 2.6 3 0 0 3 3 3 0 Glutamine amidotransferase domain Peroxidase_2 PF01328.17 EPS31088.1 - 2e-44 152.4 0.0 2.6e-44 152.0 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 RicinB_lectin_2 PF14200.6 EPS31089.1 - 0.00023 21.8 0.0 0.012 16.4 0.1 2.5 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like VCBS PF13517.6 EPS31089.1 - 1.6 9.4 5.6 1.1 9.9 0.2 2.3 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Asp PF00026.23 EPS31090.1 - 7.6e-38 130.7 4.2 1.5e-18 67.3 0.2 3.0 1 1 2 3 3 3 3 Eukaryotic aspartyl protease TAXi_N PF14543.6 EPS31090.1 - 2.3e-07 31.2 0.3 0.024 14.9 0.0 2.3 2 0 0 2 2 2 2 Xylanase inhibitor N-terminal SLATT_fungal PF18142.1 EPS31091.1 - 1e-30 106.1 0.2 1.5e-30 105.6 0.2 1.2 1 0 0 1 1 1 1 SMODS and SLOG-associating 2TM effector domain Phage_holin_3_6 PF07332.11 EPS31091.1 - 0.02 15.0 0.6 0.029 14.4 0.6 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III VCPO_N PF17897.1 EPS31092.1 - 1.2e-12 48.2 0.1 2.1e-12 47.3 0.1 1.4 1 0 0 1 1 1 1 Vanadium chloroperoxidase N-terminal domain PAP2 PF01569.21 EPS31092.1 - 6.5e-11 42.1 0.3 1.5e-10 41.0 0.3 1.5 1 1 0 1 1 1 1 PAP2 superfamily DUF4953 PF16313.5 EPS31093.1 - 7.2e-06 25.4 0.0 1.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Met-zincin Peptidase_M57 PF12388.8 EPS31093.1 - 7.7e-06 25.7 0.0 1.4e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Reprolysin_5 PF13688.6 EPS31093.1 - 1.9e-05 24.9 0.0 3e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 EPS31093.1 - 0.00012 21.8 0.0 0.00024 20.8 0.0 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.24 EPS31093.1 - 0.0016 18.3 0.3 0.0039 17.0 0.3 1.7 1 1 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.9 EPS31093.1 - 0.0047 15.9 0.1 0.0074 15.3 0.1 1.2 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_3 PF13582.6 EPS31093.1 - 0.016 15.7 0.0 0.028 14.9 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M43 PF05572.13 EPS31093.1 - 0.019 14.9 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Reprolysin_2 PF13574.6 EPS31093.1 - 0.025 14.5 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Astacin PF01400.24 EPS31093.1 - 0.047 13.3 0.0 0.08 12.6 0.0 1.3 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Peptidase_M64 PF09471.10 EPS31093.1 - 0.13 11.7 0.0 0.61 9.6 0.0 1.9 2 0 0 2 2 2 0 IgA Peptidase M64 Peptidase_M6 PF05547.11 EPS31095.1 - 3.1e-27 95.2 8.3 5.2e-23 81.3 3.7 2.7 1 1 1 2 2 2 2 Immune inhibitor A peptidase M6 FAD_binding_4 PF01565.23 EPS31096.1 - 2.8e-06 27.1 0.4 6.9e-06 25.8 0.4 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EPS31096.1 - 2.8e-05 24.1 0.0 6.2e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like GMC_oxred_C PF05199.13 EPS31097.1 - 5.2e-06 27.0 0.1 1.8e-05 25.3 0.1 1.9 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.19 EPS31097.1 - 8.2e-06 25.4 0.0 5.3e-05 22.7 0.0 2.3 2 1 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EPS31097.1 - 0.0033 16.6 0.1 0.0061 15.7 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EPS31097.1 - 0.0048 16.2 0.0 0.012 14.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EPS31097.1 - 0.065 12.6 0.1 0.097 12.0 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Acetyltransf_1 PF00583.25 EPS31099.1 - 1.2e-09 38.4 0.0 2.1e-09 37.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EPS31099.1 - 1.1e-08 35.3 0.0 2.2e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EPS31099.1 - 1.5e-07 31.4 0.0 5.9e-07 29.5 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EPS31099.1 - 0.00015 21.8 0.0 0.0039 17.2 0.0 2.5 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain PyrBI_leader PF08052.11 EPS31099.1 - 0.14 12.1 0.1 0.55 10.2 0.1 1.9 2 0 0 2 2 2 0 PyrBI operon leader peptide DUF3632 PF12311.8 EPS31101.1 - 1.4e-36 126.5 5.0 1.9e-36 126.1 5.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) DUF4347 PF14252.6 EPS31101.1 - 0.048 13.5 0.2 2.3 8.1 0.3 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4347) FliN_N PF16973.5 EPS31101.1 - 1.6 8.7 6.7 5.9 6.8 0.4 3.2 3 1 0 3 3 3 0 Flagellar motor switch protein FliN N-terminal Fungal_trans PF04082.18 EPS31102.1 - 2.8e-09 36.4 0.2 4.6e-09 35.7 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS31102.1 - 0.0002 21.4 1.7 0.0004 20.4 1.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydr_30_2 PF14587.6 EPS31103.1 - 1.1e-16 61.5 5.2 2.6e-16 60.2 5.2 1.6 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_hydro_59 PF02057.15 EPS31103.1 - 1.1e-06 28.1 0.1 1.7e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 59 AMP-binding PF00501.28 EPS31104.1 - 2.9e-82 276.5 0.0 3.7e-82 276.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EPS31104.1 - 3.2e-14 53.7 0.1 8.2e-14 52.3 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TFIID_20kDa PF03847.13 EPS31105.1 - 0.053 14.0 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A HSP70 PF00012.20 EPS31105.1 - 0.4 8.8 0.7 19 3.3 0.0 2.6 3 0 0 3 3 3 0 Hsp70 protein DUF573 PF04504.14 EPS31106.1 - 0.17 12.6 2.1 4.6 8.0 1.2 2.7 2 1 1 3 3 3 0 Protein of unknown function, DUF573 PEP_mutase PF13714.6 EPS31107.1 - 8.1e-43 146.6 0.0 9.5e-43 146.4 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 EPS31107.1 - 1.5e-21 76.5 0.1 2e-21 76.1 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family DUF1275 PF06912.11 EPS31109.1 - 3.1e-51 174.0 6.5 3.6e-51 173.8 6.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Glyco_hydro_43 PF04616.14 EPS31112.1 - 2.9e-50 171.2 5.9 2.9e-50 171.2 5.9 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 CBM_6 PF03422.15 EPS31112.1 - 3.2e-38 130.9 4.0 9.1e-38 129.4 4.0 1.8 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) DUF5010_C PF18099.1 EPS31112.1 - 4.7e-07 29.9 0.2 1.1e-06 28.7 0.2 1.6 1 0 0 1 1 1 1 DUF5010 C-terminal domain Glyco_hydro_32N PF00251.20 EPS31112.1 - 0.00039 20.1 2.5 0.00093 18.9 2.5 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Pec_lyase_C PF00544.19 EPS31113.1 - 4.9e-46 157.0 13.2 6.7e-46 156.5 13.2 1.3 1 0 0 1 1 1 1 Pectate lyase FAD_binding_3 PF01494.19 EPS31114.1 - 1.4e-15 57.4 0.0 2.7e-15 56.5 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EPS31114.1 - 3e-07 30.4 0.3 2.1e-06 27.6 0.2 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EPS31114.1 - 8.2e-06 26.0 0.0 2.5e-05 24.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EPS31114.1 - 2.2e-05 23.9 0.4 0.0057 15.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EPS31114.1 - 7.2e-05 22.8 0.1 0.0052 16.8 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 EPS31114.1 - 0.0035 16.3 0.4 0.065 12.1 0.1 2.6 3 0 0 3 3 3 1 Tryptophan halogenase Thi4 PF01946.17 EPS31114.1 - 0.01 15.1 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family MFS_1 PF07690.16 EPS31116.1 - 1.1e-19 70.6 39.1 9e-17 61.0 17.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4440 PF14534.6 EPS31117.1 - 1.7e-11 44.5 0.0 1.9e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 EPS31117.1 - 0.017 15.7 0.0 0.024 15.3 0.0 1.3 1 1 0 1 1 1 0 SnoaL-like domain DUF1348 PF07080.11 EPS31119.1 - 9.6e-57 190.5 2.1 1.1e-56 190.3 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 EPS31119.1 - 4.7e-08 33.6 0.5 6.5e-08 33.2 0.5 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 EPS31119.1 - 5.8e-06 26.7 0.3 7.3e-06 26.3 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.12 EPS31119.1 - 0.005 16.6 0.1 0.008 16.0 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase NUP PF06516.11 EPS31120.1 - 2.2e-135 450.9 0.0 2.5e-135 450.7 0.0 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) adh_short PF00106.25 EPS31121.1 - 2.9e-32 111.7 0.0 3.7e-32 111.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS31121.1 - 6.2e-27 94.7 0.0 8e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPS31121.1 - 0.0011 19.0 0.1 0.0018 18.2 0.1 1.4 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 EPS31121.1 - 0.0013 18.2 0.0 0.0019 17.7 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Glyco_hydro_4 PF02056.16 EPS31121.1 - 0.057 13.0 0.0 0.11 12.0 0.0 1.5 1 1 0 1 1 1 0 Family 4 glycosyl hydrolase Epimerase PF01370.21 EPS31121.1 - 0.12 11.8 0.1 0.66 9.4 0.1 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.16 EPS31122.1 - 4.3e-34 118.0 28.7 1.5e-33 116.2 28.6 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 EPS31122.1 - 4.3e-05 23.0 0.5 0.0001 21.7 0.5 1.5 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB BT1 PF03092.16 EPS31122.1 - 0.037 12.3 5.9 0.038 12.2 0.8 2.8 3 1 1 4 4 4 0 BT1 family ADH_zinc_N PF00107.26 EPS31124.1 - 2.4e-26 92.2 0.0 3.7e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPS31124.1 - 4.9e-23 82.6 0.0 1.1e-22 81.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPS31124.1 - 2e-10 40.5 1.4 6.8e-10 38.8 0.6 2.1 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.21 EPS31124.1 - 0.038 13.3 0.1 0.065 12.5 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GDPD PF03009.17 EPS31125.1 - 7e-31 107.9 0.0 1.3e-30 107.0 0.0 1.4 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 EPS31125.1 - 3.5e-07 30.5 1.0 1.2e-06 28.8 1.0 2.0 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family HNH_2 PF13391.6 EPS31126.1 - 2.3e-05 24.5 0.1 6.6e-05 23.0 0.1 1.8 1 0 0 1 1 1 1 HNH endonuclease DUF4569 PF15133.6 EPS31126.1 - 0.032 13.9 0.3 0.065 13.0 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) CENP-F_leu_zip PF10473.9 EPS31126.1 - 0.12 12.4 1.1 0.26 11.3 1.1 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MFS_1 PF07690.16 EPS31127.1 - 1.7e-39 135.7 28.7 1.7e-39 135.7 28.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS31127.1 - 1.6e-11 43.7 9.5 1.6e-11 43.7 9.5 3.9 1 1 2 5 5 5 1 Sugar (and other) transporter DUF2304 PF10066.9 EPS31127.1 - 4.3 7.6 6.4 6.3 7.1 0.2 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) Lactamase_B PF00753.27 EPS31128.1 - 0.0044 17.0 0.1 0.0053 16.8 0.1 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Skp1_POZ PF03931.15 EPS31128.1 - 0.11 12.7 0.0 16 5.7 0.0 2.1 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain FAD_binding_3 PF01494.19 EPS31129.1 - 6.3e-05 22.4 1.4 0.00013 21.3 0.2 1.7 1 1 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EPS31129.1 - 0.00075 19.7 0.0 0.0015 18.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EPS31129.1 - 0.018 14.3 0.0 0.035 13.3 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Fungal_trans PF04082.18 EPS31130.1 - 8.9e-10 38.0 0.0 1.4e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS31130.1 - 3.3e-06 27.1 13.9 6.3e-06 26.2 13.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LIM PF00412.22 EPS31131.1 - 6.9e-18 64.6 16.9 1.7e-11 44.2 1.7 3.1 3 0 0 3 3 3 2 LIM domain DUF4674 PF15719.5 EPS31131.1 - 0.034 14.2 0.2 0.034 14.2 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4674) zf_C2HC_14 PF18574.1 EPS31131.1 - 0.62 9.9 5.3 7.5 6.4 0.9 2.6 2 0 0 2 2 2 0 C2HC Zing finger domain Paired_CXXCH_1 PF09699.10 EPS31131.1 - 6.5 6.6 7.1 24 4.8 7.1 2.0 1 0 0 1 1 1 0 Doubled CXXCH motif (Paired_CXXCH_1) DUF3419 PF11899.8 EPS31132.1 - 2.8e-159 530.4 0.0 3.8e-159 530.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.6 EPS31132.1 - 5.7e-15 55.5 0.0 1.9e-12 47.3 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPS31132.1 - 2.3e-09 37.2 0.0 9.3e-08 32.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPS31132.1 - 7e-09 36.3 0.0 1.8e-07 31.8 0.0 3.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPS31132.1 - 2.4e-08 34.6 0.0 1.1e-07 32.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS31132.1 - 1.7e-07 31.8 0.0 6.5e-06 26.7 0.0 3.3 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPS31132.1 - 6.8e-06 25.6 0.0 1.9e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EPS31132.1 - 0.00013 21.8 0.0 0.00031 20.5 0.0 1.6 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.18 EPS31132.1 - 0.055 12.8 0.0 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 O-methyltransferase domain Methyltransf_32 PF13679.6 EPS31132.1 - 0.058 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Fungal_trans PF04082.18 EPS31133.1 - 3.4e-16 59.1 0.0 5.9e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS31133.1 - 3e-05 24.0 17.5 7.2e-05 22.8 17.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ndc1_Nup PF09531.10 EPS31133.1 - 4.8 5.8 12.7 0.088 11.5 0.4 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup SBP_bac_8 PF13416.6 EPS31134.1 - 0.0072 16.2 0.8 0.011 15.5 0.7 1.3 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein Cu-oxidase_2 PF07731.14 EPS31135.1 - 1e-21 77.1 0.0 1.7e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.22 EPS31135.1 - 1.2e-11 45.0 0.0 2.9e-11 43.7 0.0 1.5 1 1 0 1 1 1 1 Multicopper oxidase Ferric_reduct PF01794.19 EPS31136.1 - 3.5e-19 69.2 19.8 3.5e-19 69.2 19.8 2.4 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EPS31136.1 - 6.5e-11 42.3 0.0 1.3e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 EPS31136.1 - 4.7e-09 36.6 0.0 3.7e-08 33.6 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 EPS31136.1 - 0.094 13.4 0.0 2.8 8.6 0.0 2.4 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain TMEM214 PF10151.9 EPS31136.1 - 0.12 10.8 0.5 0.18 10.2 0.5 1.1 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator DUF4405 PF14358.6 EPS31136.1 - 7.7 7.2 21.4 0.069 13.7 3.9 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4405) Ctr PF04145.15 EPS31138.1 - 4.3e-33 115.0 0.0 5.6e-33 114.7 0.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF4448 PF14610.6 EPS31138.1 - 0.31 10.8 0.0 0.31 10.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) DIT1_PvcA PF05141.12 EPS31139.1 - 1.3e-60 205.2 0.0 2.4e-60 204.3 0.0 1.4 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein AMP-binding PF00501.28 EPS31139.1 - 2e-23 82.7 0.0 3.6e-23 81.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Transferase PF02458.15 EPS31139.1 - 1.1e-11 44.0 0.0 0.00014 20.7 0.1 3.0 2 1 0 2 2 2 2 Transferase family PP-binding PF00550.25 EPS31139.1 - 4.1e-06 27.0 0.1 1.1e-05 25.7 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site MFS_1 PF07690.16 EPS31140.1 - 4.4e-42 144.3 57.6 1.7e-39 135.8 57.6 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.13 EPS31140.1 - 1.3e-05 23.8 21.0 7.4e-05 21.4 21.0 2.1 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2178 PF09946.9 EPS31140.1 - 0.06 13.5 0.0 0.06 13.5 0.0 3.8 5 1 0 5 5 5 0 Predicted membrane protein (DUF2178) MFS_1 PF07690.16 EPS31141.1 - 4.8e-22 78.4 59.0 1.4e-13 50.5 32.9 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DHquinase_I PF01487.15 EPS31145.1 - 6.5e-46 157.4 0.0 8.8e-46 157.0 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase zf-RING_2 PF13639.6 EPS31146.1 - 1.3e-06 28.6 5.2 1.3e-06 28.6 5.2 1.8 2 0 0 2 2 1 1 Ring finger domain FANCL_C PF11793.8 EPS31146.1 - 0.0019 18.3 7.9 0.0028 17.8 4.6 2.2 2 0 0 2 2 2 1 FANCL C-terminal domain Prok-RING_1 PF14446.6 EPS31146.1 - 0.0022 17.9 4.7 0.0056 16.6 4.7 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 zf-ANAPC11 PF12861.7 EPS31146.1 - 0.0029 17.6 2.3 0.0029 17.6 2.3 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.29 EPS31146.1 - 0.012 15.5 5.7 0.024 14.5 5.7 1.5 1 0 0 1 1 1 0 PHD-finger SWIM PF04434.17 EPS31146.1 - 0.029 14.0 0.1 0.055 13.1 0.1 1.5 1 0 0 1 1 1 0 SWIM zinc finger zf-RING_UBOX PF13445.6 EPS31146.1 - 0.041 13.9 3.3 0.11 12.6 3.3 1.8 1 0 0 1 1 1 0 RING-type zinc-finger RINGv PF12906.7 EPS31146.1 - 0.56 10.4 6.5 1.3 9.2 6.5 1.6 1 0 0 1 1 1 0 RING-variant domain KcnmB2_inactiv PF09303.10 EPS31146.1 - 0.92 9.4 2.4 6.9 6.6 0.2 2.8 2 0 0 2 2 2 0 KCNMB2, ball and chain domain zf-RING_5 PF14634.6 EPS31146.1 - 1.8 8.6 10.9 0.23 11.4 5.5 2.2 2 0 0 2 2 2 0 zinc-RING finger domain C1_1 PF00130.22 EPS31146.1 - 3.4 7.6 7.0 0.75 9.7 2.9 2.0 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF974 PF06159.13 EPS31147.1 - 5.6e-80 268.7 0.0 6.8e-80 268.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) PhaC_N PF07167.13 EPS31147.1 - 9e-05 22.2 0.1 0.0017 18.0 0.0 2.4 2 1 1 3 3 3 1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus ASH PF15780.5 EPS31147.1 - 0.048 13.9 0.0 5.8 7.2 0.0 2.7 2 0 0 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DENN PF02141.21 EPS31148.1 - 1.8e-56 191.1 0.1 3.1e-56 190.3 0.1 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 EPS31148.1 - 5.9e-13 49.4 0.0 1.6e-12 48.0 0.0 1.8 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 EPS31148.1 - 3.7e-12 46.0 0.5 3.7e-12 46.0 0.5 2.3 2 0 0 2 2 2 1 dDENN domain C1_2 PF03107.16 EPS31148.1 - 1.9e-05 24.9 1.8 4.3e-05 23.7 1.8 1.6 1 0 0 1 1 1 1 C1 domain C1_1 PF00130.22 EPS31148.1 - 2.7e-05 24.0 6.8 5e-05 23.1 6.8 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF4042 PF13251.6 EPS31148.1 - 0.082 12.6 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4042) zf-HC5HC2H_2 PF13832.6 EPS31148.1 - 0.16 12.1 8.1 0.094 12.9 4.8 2.0 2 0 0 2 2 2 0 PHD-zinc-finger like domain PHD PF00628.29 EPS31148.1 - 0.43 10.5 8.4 0.98 9.4 7.8 1.9 1 1 1 2 2 2 0 PHD-finger Zn_ribbon_17 PF17120.5 EPS31148.1 - 0.95 9.1 6.4 1.9 8.2 6.4 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Zf_RING PF16744.5 EPS31148.1 - 5.5 7.2 7.7 17 5.6 7.7 1.8 1 1 0 1 1 1 0 KIAA1045 RING finger CENP-N PF05238.13 EPS31149.1 - 4e-137 457.9 0.0 4.5e-137 457.7 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like bZIP_2 PF07716.15 EPS31150.1 - 5.5e-13 48.8 12.2 2e-12 47.0 12.2 2.0 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EPS31150.1 - 0.00094 19.2 9.7 0.001 19.1 7.0 2.4 2 0 0 2 2 2 1 bZIP transcription factor DDRGK PF09756.9 EPS31150.1 - 0.38 10.3 11.5 0.62 9.6 11.5 1.2 1 0 0 1 1 1 0 DDRGK domain APC_u14 PF16635.5 EPS31150.1 - 0.48 11.0 7.3 1.5 9.4 7.3 1.8 1 0 0 1 1 1 0 Unstructured region on APC between SAMP and APC_crr NAD_binding_8 PF13450.6 EPS31152.1 - 7.4e-16 58.1 0.0 1.5e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 EPS31152.1 - 7.9e-10 38.6 0.0 8.2e-05 22.1 0.0 3.1 3 0 0 3 3 3 3 Flavin containing amine oxidoreductase DAO PF01266.24 EPS31152.1 - 3.1e-07 30.3 0.2 8.1e-05 22.4 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPS31152.1 - 4.7e-07 29.3 0.0 0.0015 17.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EPS31152.1 - 0.0087 15.2 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 EPS31152.1 - 0.0098 15.9 0.1 0.072 13.1 0.0 2.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding Semialdhyde_dh PF01118.24 EPS31152.1 - 0.01 16.3 0.1 0.69 10.4 0.0 2.3 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain K_oxygenase PF13434.6 EPS31152.1 - 0.02 14.1 0.1 0.36 9.9 0.0 2.5 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 EPS31152.1 - 0.027 13.3 0.0 0.04 12.8 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_3 PF01494.19 EPS31152.1 - 0.028 13.7 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 EPS31152.1 - 0.034 14.7 0.0 0.25 11.9 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.17 EPS31152.1 - 0.075 13.6 0.1 13 6.4 0.0 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Glu_dehyd_C PF16912.5 EPS31152.1 - 0.1 12.1 0.1 0.27 10.7 0.0 1.7 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus HI0933_like PF03486.14 EPS31152.1 - 0.21 10.2 0.0 0.36 9.5 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Glyco_hydro_115 PF15979.5 EPS31153.1 - 0.045 13.2 0.1 0.063 12.7 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 115 HATPase_c_3 PF13589.6 EPS31156.1 - 1.5e-16 60.4 0.0 2.8e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 EPS31156.1 - 1.2e-07 31.6 0.0 2.7e-06 27.2 0.0 2.6 3 0 0 3 3 3 1 MutL C terminal dimerisation domain HATPase_c PF02518.26 EPS31156.1 - 0.0025 18.3 0.0 0.0053 17.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RasGEF PF00617.19 EPS31157.1 - 1.6e-49 168.5 0.1 3.7e-49 167.3 0.1 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EPS31157.1 - 2.8e-15 56.4 0.0 8.2e-15 54.9 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.6 EPS31157.1 - 1.4e-06 28.1 0.0 3e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EPS31157.1 - 1.8e-05 24.2 0.0 3.6e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EPS31157.1 - 0.017 14.8 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain Med5 PF08689.10 EPS31160.1 - 4e-155 518.4 0.0 7.8e-153 510.8 0.0 3.2 1 1 0 1 1 1 1 Mediator complex subunit Med5 ELFV_dehydrog PF00208.21 EPS31162.1 - 3e-84 282.6 2.7 3.7e-84 282.2 2.7 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 EPS31162.1 - 2.3e-51 173.1 0.0 4.2e-51 172.2 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain MFS_1 PF07690.16 EPS31166.1 - 1.5e-10 40.5 30.5 1.5e-10 40.5 30.5 3.6 2 2 1 3 3 3 2 Major Facilitator Superfamily DUF997 PF06196.12 EPS31166.1 - 1.7 8.7 9.4 3.5 7.7 0.2 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF997) LapA_dom PF06305.11 EPS31166.1 - 3 7.7 4.6 28 4.6 0.4 4.0 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain Metallophos PF00149.28 EPS31167.1 - 5.3e-12 46.7 0.8 8.5e-12 46.0 0.8 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ank_2 PF12796.7 EPS31168.1 - 1.3e-46 157.1 9.5 5.6e-11 42.9 0.0 6.7 3 2 3 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EPS31168.1 - 2.1e-31 104.4 10.0 0.23 12.1 0.0 13.2 13 0 0 13 13 12 8 Ankyrin repeat Ank_4 PF13637.6 EPS31168.1 - 2.3e-28 98.2 7.0 0.0044 17.6 0.0 9.0 5 1 5 10 10 10 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 EPS31168.1 - 2e-14 53.4 15.7 0.01 16.1 0.0 10.1 5 2 6 11 11 11 3 Ankyrin repeats (many copies) Ank PF00023.30 EPS31168.1 - 1.4e-12 47.5 15.5 5.6 7.6 0.0 11.3 11 0 0 11 11 11 1 Ankyrin repeat NACHT PF05729.12 EPS31168.1 - 3.2e-10 40.2 0.2 6.1e-09 36.0 0.0 2.6 2 0 0 2 2 2 1 NACHT domain DUF3447 PF11929.8 EPS31168.1 - 1.2e-09 38.0 0.0 0.59 10.1 0.0 7.0 3 2 4 7 7 7 2 Domain of unknown function (DUF3447) AAA_16 PF13191.6 EPS31168.1 - 3.1e-06 27.7 0.5 1.5e-05 25.5 0.0 2.4 2 1 1 3 3 2 1 AAA ATPase domain NACHT_N PF17100.5 EPS31168.1 - 9e-06 25.7 2.0 2.5e-05 24.3 0.1 2.3 2 0 0 2 2 2 1 N-terminal domain of NWD NACHT-NTPase AAA_22 PF13401.6 EPS31168.1 - 8.9e-05 22.8 0.0 0.0003 21.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EPS31168.1 - 0.0068 16.8 0.0 0.07 13.5 0.0 2.4 2 0 0 2 2 2 1 RNA helicase PIF1 PF05970.14 EPS31168.1 - 0.0081 15.4 0.1 0.021 14.0 0.0 1.7 2 0 0 2 2 2 1 PIF1-like helicase AAA PF00004.29 EPS31168.1 - 0.03 14.8 0.1 0.13 12.7 0.1 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EPS31168.1 - 0.039 14.3 0.0 0.15 12.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EPS31168.1 - 0.049 13.6 0.0 0.16 11.9 0.0 1.9 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Shigella_OspC PF06128.11 EPS31168.1 - 0.087 12.5 0.9 13 5.4 0.0 3.9 3 1 1 4 4 4 0 Shigella flexneri OspC protein AAA_30 PF13604.6 EPS31168.1 - 0.11 12.2 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain CelTOS PF18659.1 EPS31168.1 - 0.12 12.9 0.5 0.81 10.1 0.3 2.6 3 0 0 3 3 2 0 Cell-traversal protein for ookinetes and sporozoites NAD_Gly3P_dh_N PF01210.23 EPS31168.1 - 0.21 11.6 2.8 8.9 6.3 0.0 4.6 5 1 1 6 6 6 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AAA_11 PF13086.6 EPS31168.1 - 1.5 8.5 7.8 0.3 10.9 2.0 2.4 2 1 0 2 2 2 0 AAA domain Cullin PF00888.22 EPS31168.1 - 2.3 6.7 7.7 0.23 10.0 2.9 1.6 2 0 0 2 2 2 0 Cullin family SLT PF01464.20 EPS31169.1 - 0.0005 19.7 0.1 0.0013 18.4 0.1 1.7 1 0 0 1 1 1 1 Transglycosylase SLT domain LysM PF01476.20 EPS31169.1 - 0.0014 18.6 0.2 0.0051 16.8 0.0 2.0 2 0 0 2 2 2 1 LysM domain HrpF PF06266.12 EPS31169.1 - 0.13 12.6 0.1 0.41 11.0 0.1 1.8 1 0 0 1 1 1 0 HrpF protein SOG2 PF10428.9 EPS31169.1 - 8 5.5 11.1 11 5.1 11.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DPBB_1 PF03330.18 EPS31170.1 - 0.0045 17.2 0.1 0.013 15.7 0.1 2.0 1 1 0 1 1 1 1 Lytic transglycolase DUF3275 PF11679.8 EPS31170.1 - 1.1 9.3 6.9 1.7 8.6 6.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Macoilin PF09726.9 EPS31170.1 - 1.3 7.5 3.9 1.5 7.3 3.9 1.1 1 0 0 1 1 1 0 Macoilin family SOG2 PF10428.9 EPS31170.1 - 5.5 6.1 17.0 8.1 5.5 17.0 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Ribonuc_red_lgC PF02867.15 EPS31172.1 - 1.3e-183 611.4 0.0 1.8e-183 610.9 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EPS31172.1 - 5.1e-23 80.9 0.0 1.1e-22 79.8 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 EPS31172.1 - 3.7e-16 59.5 0.1 1e-15 58.0 0.1 1.8 1 0 0 1 1 1 1 ATP cone domain Ribosomal_60s PF00428.19 EPS31172.1 - 2.5 8.7 8.2 8.7 7.0 8.2 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein PRK PF00485.18 EPS31174.1 - 3.7e-07 30.1 0.0 5.2e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EPS31174.1 - 0.00019 22.0 0.0 0.0011 19.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 EPS31174.1 - 0.00064 19.4 0.0 0.47 10.1 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_16 PF13191.6 EPS31174.1 - 0.0025 18.2 0.0 0.0038 17.6 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 EPS31174.1 - 0.0059 16.8 0.0 0.31 11.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EPS31174.1 - 0.019 15.3 0.1 0.13 12.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EPS31174.1 - 0.026 15.0 0.0 0.15 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EPS31174.1 - 0.026 13.8 0.0 0.064 12.5 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin NB-ARC PF00931.22 EPS31174.1 - 0.034 13.3 0.0 0.049 12.8 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain dNK PF01712.19 EPS31174.1 - 0.037 13.9 0.0 0.076 12.9 0.0 1.6 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_28 PF13521.6 EPS31174.1 - 0.1 12.8 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EPS31174.1 - 0.13 11.5 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 EPS31174.1 - 0.17 11.0 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein KTI12 PF08433.10 EPS31174.1 - 0.17 11.3 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NACHT PF05729.12 EPS31174.1 - 0.17 11.8 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Viral_helicase1 PF01443.18 EPS31174.1 - 0.17 11.6 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.14 EPS31174.1 - 0.2 11.7 0.0 0.42 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Pkinase PF00069.25 EPS31176.1 - 2.7e-72 243.3 0.0 8.4e-72 241.7 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS31176.1 - 2.8e-50 171.0 0.0 6.4e-50 169.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase DUF383 PF04063.14 EPS31176.1 - 0.0004 20.1 0.6 0.00099 18.8 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF383) Pkinase_fungal PF17667.1 EPS31176.1 - 0.0019 17.1 0.0 0.0038 16.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase DUF913 PF06025.12 EPS31176.1 - 0.025 13.5 2.3 5.9 5.8 0.0 3.5 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) Kinase-like PF14531.6 EPS31176.1 - 0.032 13.5 0.0 0.41 9.9 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Arm PF00514.23 EPS31176.1 - 0.086 12.9 0.0 20 5.4 0.0 3.9 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 EPS31176.1 - 0.79 8.2 7.6 0.22 10.0 2.6 2.1 2 1 0 3 3 3 0 Adaptin N terminal region ABC1 PF03109.16 EPS31177.1 - 1.4e-34 118.8 0.0 2.3e-34 118.1 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Ig_mannosidase PF17753.1 EPS31177.1 - 0.0057 16.4 0.0 2.7 7.8 0.0 2.6 2 0 0 2 2 2 2 Ig-fold domain NifU_N PF01592.16 EPS31178.1 - 2.4e-54 182.9 0.1 3.2e-54 182.5 0.1 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain Mito_carr PF00153.27 EPS31180.1 - 2.5e-64 213.2 2.5 5.9e-22 77.4 0.1 3.4 2 2 1 3 3 3 3 Mitochondrial carrier protein TsaE PF02367.17 EPS31180.1 - 0.05 13.6 0.0 0.09 12.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE UCR_14kD PF02271.16 EPS31181.1 - 6e-44 148.1 0.2 6.9e-44 147.9 0.2 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Ferritin PF00210.24 EPS31181.1 - 0.044 13.7 0.0 0.23 11.4 0.0 1.9 1 1 0 1 1 1 0 Ferritin-like domain HhH-GPD PF00730.25 EPS31182.1 - 2.1e-13 50.6 0.0 3.5e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HMG14_17 PF01101.18 EPS31182.1 - 8.9 7.3 12.7 34 5.5 12.5 2.0 1 1 1 2 2 2 0 HMG14 and HMG17 Ecm33 PF12454.8 EPS31183.1 - 1.8e-14 53.6 2.9 1.8e-14 53.6 2.9 2.4 2 0 0 2 2 2 1 GPI-anchored cell wall organization protein LRR_5 PF13306.6 EPS31183.1 - 4.1e-06 26.8 0.1 0.12 12.3 0.0 2.7 1 1 0 2 2 2 2 BspA type Leucine rich repeat region (6 copies) SR-25 PF10500.9 EPS31183.1 - 3.6 7.1 9.3 5.1 6.7 9.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3450 PF11932.8 EPS31184.1 - 0.0068 15.7 4.0 0.011 15.0 4.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Terpene_synth_C PF03936.16 EPS31184.1 - 0.061 12.7 0.1 0.088 12.1 0.1 1.1 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain VPS28 PF03997.12 EPS31184.1 - 0.064 12.9 0.9 0.11 12.2 0.9 1.3 1 0 0 1 1 1 0 VPS28 protein Peptidase_S30 PF01577.16 EPS31184.1 - 0.077 12.6 0.3 0.13 11.9 0.3 1.2 1 0 0 1 1 1 0 Potyvirus P1 protease DivIC PF04977.15 EPS31184.1 - 0.27 11.0 2.2 0.57 10.0 2.2 1.6 1 0 0 1 1 1 0 Septum formation initiator YabA PF06156.13 EPS31184.1 - 1.9 9.2 5.6 1.6 9.4 2.7 2.1 2 0 0 2 2 2 0 Initiation control protein YabA QWRF PF04484.12 EPS31185.1 - 2.4 7.9 6.0 3.5 7.3 6.0 1.2 1 0 0 1 1 1 0 QWRF family NUDE_C PF04880.13 EPS31185.1 - 6.2 7.3 8.2 11 6.5 8.2 1.3 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Anp1 PF03452.14 EPS31186.1 - 4.4e-109 364.0 0.0 5.4e-109 363.7 0.0 1.1 1 0 0 1 1 1 1 Anp1 YCII PF03795.14 EPS31187.1 - 1.5e-09 38.1 0.0 1.9e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Peptidase_M24 PF00557.24 EPS31188.1 - 2.2e-43 148.4 0.1 2.8e-43 148.0 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Glyco_hydro_35 PF01301.19 EPS31188.1 - 0.13 11.9 0.6 0.45 10.1 0.2 1.9 2 0 0 2 2 2 0 Glycosyl hydrolases family 35 CCDC106 PF15794.5 EPS31188.1 - 0.16 11.7 2.3 0.27 10.9 2.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DnaJ PF00226.31 EPS31189.1 - 1e-21 76.8 1.0 1.7e-21 76.1 1.0 1.4 1 0 0 1 1 1 1 DnaJ domain Porin_3 PF01459.22 EPS31190.1 - 2.1e-77 260.2 4.8 2.3e-77 260.1 4.8 1.0 1 0 0 1 1 1 1 Eukaryotic porin Asn_synthase PF00733.21 EPS31191.1 - 3.7e-96 322.9 0.4 1e-55 189.9 0.1 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 EPS31191.1 - 1.2e-38 131.7 0.0 2.1e-38 131.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EPS31191.1 - 9.5e-29 100.3 0.0 1.9e-28 99.3 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EPS31191.1 - 5.5e-06 26.0 0.0 1.2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 EPS31191.1 - 0.0019 17.4 0.1 0.0077 15.4 0.0 2.1 2 1 0 2 2 2 1 NAD synthase UQ_con PF00179.26 EPS31192.1 - 3.4e-49 166.1 0.0 3.9e-49 165.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EPS31192.1 - 2.2e-05 24.2 0.0 3.3e-05 23.6 0.0 1.4 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EPS31192.1 - 0.1 12.9 3.2 0.31 11.3 3.2 1.8 1 1 0 1 1 1 0 RWD domain G-patch PF01585.23 EPS31193.1 - 1.5e-08 34.4 1.9 3.1e-08 33.4 1.9 1.5 1 0 0 1 1 1 1 G-patch domain RRM_1 PF00076.22 EPS31193.1 - 1.7e-05 24.5 0.0 4.4e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FA_desaturase PF00487.24 EPS31194.1 - 2.3e-24 86.6 12.7 3.1e-24 86.2 12.7 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 EPS31194.1 - 4.3e-18 64.5 0.2 7.5e-18 63.7 0.2 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Motile_Sperm PF00635.26 EPS31195.1 - 2.7e-26 91.6 0.4 6.5e-26 90.3 0.3 1.7 1 1 1 2 2 2 1 MSP (Major sperm protein) domain FixG_C PF11614.8 EPS31195.1 - 0.026 14.8 0.1 0.04 14.1 0.1 1.3 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase ASH PF15780.5 EPS31195.1 - 0.048 13.9 0.1 0.14 12.4 0.1 1.8 2 0 0 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF756 PF05506.12 EPS31195.1 - 0.13 13.2 0.0 0.26 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF756) NUP50 PF08911.11 EPS31195.1 - 0.18 12.5 1.5 0.67 10.7 0.1 2.4 2 0 0 2 2 2 0 NUP50 (Nucleoporin 50 kDa) UBA PF00627.31 EPS31196.1 - 1e-05 25.3 0.6 3e-05 23.8 0.1 2.1 2 0 0 2 2 2 1 UBA/TS-N domain UBX PF00789.20 EPS31196.1 - 0.00024 21.2 0.6 0.00056 20.1 0.1 2.0 2 0 0 2 2 2 1 UBX domain zf-C2H2_2 PF12756.7 EPS31196.1 - 0.11 12.9 0.6 0.11 12.9 0.6 2.0 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 EPS31196.1 - 0.18 12.4 0.2 0.33 11.5 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type Crystallin PF00525.18 EPS31196.1 - 0.21 11.8 0.0 0.35 11.1 0.0 1.3 1 0 0 1 1 1 0 Alpha crystallin A chain, N terminal Exonuc_VII_L PF02601.15 EPS31196.1 - 0.46 10.0 13.6 0.58 9.7 13.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit ACR_tran PF00873.19 EPS31196.1 - 1.5 6.4 7.8 1.8 6.1 7.8 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family V_ATPase_I PF01496.19 EPS31196.1 - 2.4 6.0 11.2 2.7 5.8 11.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF5401 PF17380.2 EPS31196.1 - 3.5 5.6 28.5 4.2 5.3 28.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) RR_TM4-6 PF06459.12 EPS31196.1 - 4.7 7.0 28.3 7 6.4 28.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GAGA_bind PF06217.12 EPS31196.1 - 6 7.1 14.3 9.4 6.4 14.3 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family GREB1 PF15782.5 EPS31196.1 - 8.6 3.3 14.4 9.6 3.2 14.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Rad52_Rad22 PF04098.15 EPS31197.1 - 9e-60 201.0 0.1 1.2e-59 200.7 0.1 1.1 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Terpene_synth_C PF03936.16 EPS31199.1 - 2.2e-08 33.8 0.9 1.4e-07 31.1 0.7 2.0 2 0 0 2 2 2 1 Terpene synthase family, metal binding domain adh_short PF00106.25 EPS31200.1 - 5.2e-36 123.9 0.0 6.6e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS31200.1 - 3.1e-26 92.4 0.0 4.4e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPS31200.1 - 3.1e-07 30.5 0.0 6.8e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 KR domain RHS PF03527.14 EPS31200.1 - 0.042 13.6 0.4 0.11 12.2 0.1 1.8 2 0 0 2 2 2 0 RHS protein GlgS PF08971.11 EPS31200.1 - 0.076 13.0 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Glycogen synthesis protein NAD_binding_10 PF13460.6 EPS31200.1 - 0.19 11.6 0.0 0.26 11.1 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding Glyco_hydro_32N PF00251.20 EPS31201.1 - 1.2e-43 149.8 5.0 1.2e-42 146.6 5.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 EPS31201.1 - 1e-32 113.4 0.1 1.7e-32 112.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal DUF4975 PF16346.5 EPS31201.1 - 2.1e-05 24.7 0.5 3.3e-05 24.0 0.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4975) BNR PF02012.20 EPS31201.1 - 0.01 15.7 0.2 0.061 13.3 0.2 2.5 1 0 0 1 1 1 0 BNR/Asp-box repeat CHB_HEX_C PF03174.13 EPS31201.1 - 0.15 12.1 0.1 0.72 9.9 0.1 2.1 1 0 0 1 1 1 0 Chitobiase/beta-hexosaminidase C-terminal domain Big_9 PF17963.1 EPS31201.1 - 0.16 12.7 2.7 1.1 10.0 0.1 3.0 2 0 0 2 2 2 0 Bacterial Ig domain MCRA PF06100.11 EPS31202.1 - 2.8e-158 527.8 0.0 3.2e-158 527.6 0.0 1.0 1 0 0 1 1 1 1 MCRA family Cas9-BH PF16593.5 EPS31202.1 - 0.6 9.9 3.3 18 5.2 2.7 2.9 2 0 0 2 2 2 0 Bridge helix of CRISPR-associated endonuclease Cas9 JHD PF17811.1 EPS31203.1 - 1.2e-09 38.6 0.2 2.5e-09 37.6 0.2 1.5 1 0 0 1 1 1 1 Jumonji helical domain JmjC PF02373.22 EPS31203.1 - 5.5e-09 36.5 0.0 9.2e-08 32.5 0.0 2.7 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 EPS31203.1 - 1e-08 35.2 0.0 3e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Cupin-like domain PHD PF00628.29 EPS31203.1 - 2e-08 34.0 5.0 2e-08 34.0 5.0 2.6 3 0 0 3 3 3 1 PHD-finger PHD_Oberon PF07227.11 EPS31203.1 - 0.012 15.5 1.6 0.029 14.3 1.6 1.5 1 0 0 1 1 1 0 PHD - plant homeodomain finger protein PHD_2 PF13831.6 EPS31203.1 - 0.029 13.9 3.1 0.044 13.4 1.4 2.3 2 0 0 2 2 2 0 PHD-finger Zn_clus PF00172.18 EPS31203.1 - 9.3 6.5 30.9 0.41 10.8 6.1 3.5 3 1 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.22 EPS31205.1 - 3.2e-19 68.5 0.2 5.5e-19 67.8 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EPS31205.1 - 2.7e-06 27.0 0.1 3.1e-06 26.8 0.1 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EPS31205.1 - 0.0042 16.9 0.0 0.0063 16.4 0.0 1.2 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_8 PF11835.8 EPS31205.1 - 0.077 13.2 0.0 0.095 12.9 0.0 1.2 1 0 0 1 1 1 0 RRM-like domain STIMATE PF12400.8 EPS31206.1 - 1.5e-39 135.4 3.4 2.3e-39 134.8 3.4 1.3 1 0 0 1 1 1 1 STIMATE family DUF4229 PF14012.6 EPS31206.1 - 0.091 12.9 0.1 0.34 11.0 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) ANAPC4_WD40 PF12894.7 EPS31208.1 - 2.7e-05 24.4 0.1 11 6.4 0.0 4.7 5 2 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EPS31208.1 - 0.04 14.8 2.3 78 4.4 0.0 5.4 6 0 0 6 6 6 0 WD domain, G-beta repeat Vps62 PF06101.11 EPS31209.1 - 5.2e-11 41.6 0.7 1.1e-10 40.5 0.7 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 62 ELK PF03789.13 EPS31209.1 - 0.46 10.6 3.2 0.82 9.8 3.2 1.4 1 0 0 1 1 1 0 ELK domain TFIIIC_sub6 PF10419.9 EPS31211.1 - 3.8e-24 84.4 0.1 1.6e-23 82.3 0.0 2.0 2 0 0 2 2 2 1 TFIIIC subunit triple barrel domain DUF3198 PF11433.8 EPS31213.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3198) ELFV_dehydrog PF00208.21 EPS31216.1 - 4.2e-68 229.7 0.0 6.4e-68 229.1 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 EPS31216.1 - 1.8e-17 62.3 0.0 3.9e-13 47.9 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 EPS31216.1 - 0.0067 16.3 0.0 0.025 14.5 0.0 1.9 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DUF2204 PF09970.9 EPS31217.1 - 0.0014 18.3 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF2204) PolyA_pol PF01743.20 EPS31217.1 - 0.092 13.2 0.1 0.36 11.3 0.0 1.9 2 0 0 2 2 2 0 Poly A polymerase head domain Glycos_transf_1 PF00534.20 EPS31217.1 - 0.16 11.5 0.0 0.22 11.1 0.0 1.3 1 1 0 1 1 1 0 Glycosyl transferases group 1 Metallophos PF00149.28 EPS31218.1 - 4.5e-13 50.2 0.8 6.8e-13 49.6 0.8 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EPS31218.1 - 3.6e-06 27.3 0.0 2.8e-05 24.4 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MFS_1 PF07690.16 EPS31221.1 - 1.5e-21 76.8 27.1 5.3e-21 74.9 18.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS31221.1 - 1.9e-16 60.0 1.4 1.9e-16 60.0 1.4 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EPS31221.1 - 0.0023 16.4 2.9 0.0038 15.7 2.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Tmemb_170 PF10190.9 EPS31221.1 - 0.026 14.9 3.5 0.026 14.9 3.5 3.2 4 2 1 5 5 5 0 Putative transmembrane protein 170 DUF3112 PF11309.8 EPS31221.1 - 0.18 11.2 4.2 0.73 9.2 4.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3112) PhyH PF05721.13 EPS31222.1 - 1.8e-07 31.7 0.1 4e-07 30.5 0.1 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 EPS31222.1 - 0.00051 18.9 0.0 0.3 9.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_5 PF13759.6 EPS31222.1 - 0.13 12.7 0.0 0.28 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Peptidase_S15 PF02129.18 EPS31224.1 - 8.3e-43 146.9 1.6 9.2e-41 140.2 0.1 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.10 EPS31224.1 - 1.8e-33 116.4 0.0 2.7e-33 115.8 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S9 PF00326.21 EPS31224.1 - 0.0049 16.4 0.3 0.0049 16.4 0.3 2.1 3 1 0 3 3 3 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EPS31224.1 - 0.012 14.9 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 AXE1 PF05448.12 EPS31224.1 - 0.078 11.6 0.1 3 6.4 0.0 2.5 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) Fungal_trans PF04082.18 EPS31225.1 - 8.4e-19 67.6 0.3 4.7e-18 65.2 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS31225.1 - 6.2e-09 35.8 12.3 1.1e-08 35.1 12.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UL2 PF08196.11 EPS31225.1 - 0.24 11.4 0.5 35 4.4 0.0 2.5 2 0 0 2 2 2 0 UL2 protein LOR PF04525.12 EPS31226.1 - 0.00016 21.3 0.1 0.04 13.5 0.0 2.3 2 0 0 2 2 2 2 LURP-one-related ThrE PF06738.12 EPS31228.1 - 3.8e-69 232.7 18.3 3.2e-61 206.8 5.9 2.2 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 EPS31228.1 - 1.9e-12 47.4 8.3 1.9e-12 47.4 8.3 2.7 3 0 0 3 3 3 1 Threonine/Serine exporter, ThrE Tom5 PF10642.9 EPS31228.1 - 0.038 14.0 1.0 0.27 11.3 0.1 2.5 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase DUF2934 PF11154.8 EPS31228.1 - 0.045 13.4 0.2 0.081 12.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2934) Auxin_repressed PF05564.12 EPS31228.1 - 1.1 10.0 5.5 0.74 10.5 2.9 2.2 2 0 0 2 2 2 0 Dormancy/auxin associated protein Sugar_tr PF00083.24 EPS31229.1 - 3.7e-73 246.9 23.2 4.4e-73 246.7 23.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS31229.1 - 4e-13 49.0 44.4 1.8e-07 30.4 19.0 2.8 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.7 EPS31229.1 - 0.29 9.9 18.0 0.13 11.1 3.5 2.7 2 1 0 3 3 3 0 MFS_1 like family PPR_2 PF13041.6 EPS31230.1 - 0.00029 21.0 0.0 28 5.0 0.0 6.0 6 1 2 8 8 8 1 PPR repeat family PPR PF01535.20 EPS31230.1 - 0.0017 18.5 0.5 22 5.6 0.1 5.0 4 0 0 4 4 4 1 PPR repeat PPR_long PF17177.4 EPS31230.1 - 0.0075 15.7 1.6 0.044 13.1 0.9 2.6 3 1 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 EPS31230.1 - 0.0084 16.2 0.7 25 5.1 0.0 4.5 6 0 0 6 6 6 1 Pentatricopeptide repeat domain Glyco_hydro_67C PF07477.12 EPS31230.1 - 0.017 14.7 0.5 0.072 12.6 0.1 2.1 2 1 0 2 2 2 0 Glycosyl hydrolase family 67 C-terminus TPR_14 PF13428.6 EPS31230.1 - 0.099 13.5 0.0 63 4.8 0.0 4.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_S18 PF01084.20 EPS31231.1 - 1.5e-13 50.7 0.0 3.4e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S18 DUF963 PF06131.11 EPS31232.1 - 7.9e-12 44.4 61.2 6.7e-11 41.4 25.5 6.1 5 1 1 6 6 6 2 Schizosaccharomyces pombe repeat of unknown function (DUF963) PAN_1 PF00024.26 EPS31232.1 - 1.5e-05 24.9 0.6 6.7e-05 22.8 0.6 2.1 1 0 0 1 1 1 1 PAN domain WD40 PF00400.32 EPS31233.1 - 5.3e-28 96.7 35.2 2.3e-05 25.1 0.5 10.7 9 2 1 10 10 10 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS31233.1 - 2e-19 69.7 7.1 5.5e-07 29.8 0.0 7.4 3 3 5 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EPS31233.1 - 3.3e-07 30.4 0.0 0.23 11.3 0.0 3.9 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EPS31233.1 - 0.0014 17.6 1.8 0.96 8.3 0.0 4.3 4 2 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein RAB3GAP2_N PF14655.6 EPS31233.1 - 0.0032 16.8 0.0 0.018 14.3 0.0 2.0 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus PD40 PF07676.12 EPS31233.1 - 0.0045 16.9 0.8 26 4.9 0.0 4.8 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat WD40_3 PF15911.5 EPS31233.1 - 0.082 12.9 0.0 4.9 7.2 0.0 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat Nup160 PF11715.8 EPS31233.1 - 0.11 11.2 0.1 0.25 9.9 0.1 1.6 1 1 1 2 2 2 0 Nucleoporin Nup120/160 IRF PF00605.17 EPS31233.1 - 0.21 11.9 1.4 21 5.5 0.2 2.5 2 0 0 2 2 2 0 Interferon regulatory factor transcription factor FUSC_2 PF13515.6 EPS31234.1 - 1.3e-30 106.1 8.5 1.3e-30 106.1 8.5 2.6 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 EPS31234.1 - 5.4e-06 26.4 2.7 6.1e-06 26.2 0.8 2.1 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 ALMT PF11744.8 EPS31234.1 - 0.00034 19.6 18.0 0.66 8.7 0.0 4.1 3 1 0 3 3 3 2 Aluminium activated malate transporter Phage_holin_Dp1 PF16938.5 EPS31234.1 - 0.021 15.0 2.4 0.25 11.6 0.0 3.4 4 0 0 4 4 4 0 Putative phage holin Dp-1 RCS1 PF07326.11 EPS31234.1 - 0.056 13.4 0.1 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Regulator of chromosome segregation 1 Phage_holin_3_1 PF05106.12 EPS31234.1 - 2.2 8.8 8.7 0.53 10.8 3.1 2.9 2 1 1 3 3 3 0 Phage holin family (Lysis protein S) SAGA-Tad1 PF12767.7 EPS31235.1 - 4.4e-57 193.5 0.0 5.8e-57 193.1 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit PRP1_N PF06424.12 EPS31237.1 - 5e-53 179.5 8.8 1.3e-52 178.1 8.8 1.8 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 EPS31237.1 - 2e-29 99.8 35.0 0.00035 21.2 0.0 13.8 5 3 9 14 14 13 9 Tetratricopeptide repeat TPR_19 PF14559.6 EPS31237.1 - 2.8e-29 101.4 14.8 2.5e-07 31.1 0.2 9.7 6 3 2 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 EPS31237.1 - 5.2e-12 46.2 27.4 0.0093 16.6 0.0 8.6 5 2 6 11 11 11 5 Tetratricopeptide repeat TPR_2 PF07719.17 EPS31237.1 - 5e-11 41.8 13.9 0.1 12.8 0.0 9.0 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_11 PF13414.6 EPS31237.1 - 5.2e-11 42.1 0.1 0.43 10.3 0.0 7.5 7 1 1 8 8 7 2 TPR repeat TPR_8 PF13181.6 EPS31237.1 - 1.3e-08 34.4 0.7 0.89 9.9 0.0 6.9 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 EPS31237.1 - 7.5e-07 29.1 4.0 14 6.3 0.0 8.3 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_1 PF00515.28 EPS31237.1 - 1.3e-06 27.9 1.3 0.075 12.9 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_21 PF09976.9 EPS31237.1 - 1.8e-05 24.5 13.5 0.015 15.0 2.0 4.4 2 1 1 4 4 4 2 Tetratricopeptide repeat-like domain TPR_15 PF13429.6 EPS31237.1 - 2.9e-05 23.4 8.4 2.9e-05 23.4 8.4 5.0 4 2 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EPS31237.1 - 0.00059 20.1 3.4 0.86 9.9 0.0 6.4 5 2 2 7 7 7 1 Tetratricopeptide repeat NARP1 PF12569.8 EPS31237.1 - 0.00061 18.8 11.7 0.48 9.3 0.0 5.4 3 1 1 5 5 5 1 NMDA receptor-regulated protein 1 ANAPC3 PF12895.7 EPS31237.1 - 0.0012 19.0 0.4 8.5 6.7 0.0 4.4 3 1 0 4 4 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EPS31237.1 - 0.019 15.0 0.1 74 3.7 0.0 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat ZNRF_3_ecto PF18212.1 EPS31237.1 - 0.028 14.4 0.1 20 5.2 0.0 4.3 6 0 0 6 6 5 0 ZNRF-3 Ectodomain DUF3808 PF10300.9 EPS31237.1 - 0.056 12.2 3.0 3.5 6.3 0.0 3.9 5 0 0 5 5 5 0 Protein of unknown function (DUF3808) PTPRCAP PF15713.5 EPS31237.1 - 0.084 13.2 7.0 0.36 11.1 7.0 2.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Suf PF05843.14 EPS31237.1 - 0.19 11.6 3.8 23 4.9 0.2 3.8 4 1 0 4 4 4 0 Suppressor of forked protein (Suf) TPR_9 PF13371.6 EPS31237.1 - 0.26 11.5 11.6 6.7 6.9 0.0 5.6 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 EPS31237.1 - 0.68 10.7 14.9 2.2e+02 2.8 0.0 8.6 9 0 0 9 9 9 0 Tetratricopeptide repeat RrnaAD PF00398.20 EPS31238.1 - 6e-63 212.4 0.0 8.5e-63 211.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EPS31238.1 - 2.5e-08 34.5 0.0 5.2e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS31238.1 - 4.3e-06 27.3 0.0 9.3e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPS31238.1 - 0.0002 22.0 0.0 0.00044 20.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPS31238.1 - 0.00057 19.7 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EPS31238.1 - 0.0012 18.6 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EPS31238.1 - 0.0027 17.5 0.0 0.0084 15.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 EPS31238.1 - 0.0056 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 EPS31238.1 - 0.0064 16.0 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 EPS31238.1 - 0.0074 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Met_10 PF02475.16 EPS31238.1 - 0.02 14.7 0.0 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein AAA_lid_4 PF17864.1 EPS31238.1 - 0.027 14.2 0.0 0.1 12.3 0.0 1.9 2 0 0 2 2 2 0 RuvB AAA lid domain Methyltransf_18 PF12847.7 EPS31238.1 - 0.058 13.3 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_28 PF02636.17 EPS31238.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase RabGAP-TBC PF00566.18 EPS31239.1 - 9.3e-52 175.8 0.0 2.9e-51 174.2 0.0 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Cwf_Cwc_15 PF04889.12 EPS31239.1 - 0.087 12.5 1.1 0.14 11.9 1.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Med13_C PF06333.12 EPS31239.1 - 0.14 11.4 0.5 0.23 10.7 0.5 1.3 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain CENP-B_dimeris PF09026.10 EPS31239.1 - 0.19 12.1 6.2 0.4 11.1 6.2 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 EPS31239.1 - 0.41 9.9 0.9 0.64 9.3 0.9 1.2 1 0 0 1 1 1 0 NOA36 protein SelP_N PF04592.14 EPS31240.1 - 0.2 11.0 5.0 0.2 11.0 5.0 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF1180 PF06679.12 EPS31240.1 - 2.9 8.3 6.2 3.6 8.0 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) RRM_1 PF00076.22 EPS31241.1 - 2.9e-35 119.9 0.2 1e-16 60.5 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EPS31241.1 - 4.9e-10 39.4 0.2 0.0014 18.7 0.1 2.9 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 EPS31241.1 - 0.0016 18.4 0.0 2.1 8.4 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EPS31241.1 - 0.0039 17.2 0.0 4.1 7.5 0.0 2.8 2 0 0 2 2 2 2 RNA binding motif Pkinase_fungal PF17667.1 EPS31242.1 - 8.3e-127 423.3 0.0 1e-126 423.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EPS31242.1 - 0.065 13.2 0.0 0.17 11.8 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 EPS31242.1 - 0.091 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain MauJ PF17419.2 EPS31242.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Methylamine utilization protein MauJ TRP PF06011.12 EPS31243.1 - 2.5e-139 464.7 16.3 3.3e-139 464.3 16.3 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EPS31243.1 - 4.8e-40 137.1 1.6 8.2e-40 136.4 1.6 1.4 1 0 0 1 1 1 1 ML-like domain HemY_N PF07219.13 EPS31243.1 - 0.13 12.5 4.3 2.8 8.2 1.4 3.4 3 0 0 3 3 3 0 HemY protein N-terminus ETRAMP PF09716.10 EPS31243.1 - 0.69 10.0 0.0 0.69 10.0 0.0 3.4 4 0 0 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) FA_desaturase PF00487.24 EPS31243.1 - 2 8.2 10.0 0.029 14.2 0.9 2.3 1 1 0 2 2 2 0 Fatty acid desaturase DUF2663 PF10864.8 EPS31243.1 - 2 8.8 8.0 1.2 9.6 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2663) CSTF1_dimer PF16699.5 EPS31244.1 - 0.14 11.9 0.0 0.14 11.9 0.0 1.1 1 0 0 1 1 1 0 Cleavage stimulation factor subunit 1, dimerisation domain Hep_59 PF07052.11 EPS31245.1 - 4.5e-14 53.1 0.1 4.5e-14 53.1 0.1 4.1 3 3 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 Actin PF00022.19 EPS31246.1 - 3.7e-150 500.1 0.0 4.2e-150 499.9 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EPS31246.1 - 0.0037 16.1 0.0 4.3 6.1 0.0 3.0 3 0 0 3 3 3 2 MreB/Mbl protein FtsA PF14450.6 EPS31246.1 - 0.091 13.2 0.0 0.23 11.9 0.0 2.0 2 1 0 2 2 2 0 Cell division protein FtsA MFS_1 PF07690.16 EPS31247.1 - 1.2e-31 110.0 51.8 1.2e-31 110.0 51.8 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Dabb PF07876.12 EPS31248.1 - 3.2e-08 34.1 0.0 4.8e-08 33.5 0.0 1.3 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain Thioredoxin_2 PF13098.6 EPS31248.1 - 0.11 13.0 0.0 16 6.0 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like domain Fungal_trans PF04082.18 EPS31249.1 - 1.7e-09 37.1 0.8 2.6e-08 33.2 0.5 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS31249.1 - 8.9e-08 32.1 7.6 2.1e-07 30.9 7.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 EPS31249.1 - 1.1e-07 31.9 15.5 0.00041 20.6 1.8 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EPS31249.1 - 6.2e-07 29.6 15.9 7.2e-06 26.2 1.3 3.7 3 1 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EPS31249.1 - 2.5e-05 24.7 16.2 0.00071 20.2 1.3 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EPS31249.1 - 0.094 13.0 0.4 0.094 13.0 0.4 2.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 EPS31249.1 - 1.3 9.3 7.1 0.31 11.4 2.7 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding AMP-binding PF00501.28 EPS31251.1 - 4e-153 510.0 0.0 2.2e-81 273.6 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 EPS31251.1 - 8e-97 324.8 6.6 6.7e-39 133.8 0.0 5.2 4 1 0 4 4 4 4 Condensation domain PP-binding PF00550.25 EPS31251.1 - 6e-14 52.2 0.2 3.9e-06 27.1 0.0 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EPS31251.1 - 1.9e-08 35.2 0.1 0.0029 18.6 0.0 2.7 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Peptidase_C74 PF12387.8 EPS31254.1 - 0.015 14.8 0.4 0.021 14.3 0.4 1.2 1 0 0 1 1 1 0 Pestivirus NS2 peptidase Cache_3-Cache_2 PF17201.4 EPS31254.1 - 0.14 11.4 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Cache 3/Cache 2 fusion domain zf-C4_Topoisom PF01396.19 EPS31255.1 - 0.022 14.5 0.0 0.056 13.2 0.0 1.7 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger Fungal_trans PF04082.18 EPS31258.1 - 7e-08 31.8 0.0 1.3e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain UDG PF03167.19 EPS31259.1 - 1.6e-22 80.2 0.2 4.1e-22 78.8 0.1 1.7 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily ABC_trans_N PF14510.6 EPS31259.1 - 0.1 13.2 1.5 7.7 7.2 0.1 2.6 2 0 0 2 2 2 0 ABC-transporter N-terminal Thioredoxin PF00085.20 EPS31260.1 - 1.8e-65 217.4 4.7 2.3e-32 111.1 0.1 4.2 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 EPS31260.1 - 2e-47 161.5 2.3 2.9e-35 121.8 0.3 3.5 2 1 1 3 3 3 3 Thioredoxin-like domain Calsequestrin PF01216.17 EPS31260.1 - 4.1e-10 39.3 3.5 2.3e-09 36.8 0.2 2.4 1 1 1 2 2 2 1 Calsequestrin Thioredoxin_7 PF13899.6 EPS31260.1 - 2.6e-08 33.9 0.1 0.0022 18.1 0.0 3.0 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EPS31260.1 - 1e-07 32.4 2.0 0.02 15.3 0.0 3.4 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EPS31260.1 - 6.5e-07 29.6 0.1 0.17 12.2 0.0 4.2 3 1 1 4 4 4 2 Thioredoxin-like OST3_OST6 PF04756.13 EPS31260.1 - 1.2e-06 28.1 0.4 0.0084 15.5 0.0 3.3 2 1 1 3 3 3 2 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 EPS31260.1 - 1.7e-06 27.9 0.1 0.0051 16.7 0.0 2.7 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.10 EPS31260.1 - 2.4e-05 24.1 1.3 0.23 11.2 0.0 3.4 3 0 0 3 3 3 2 Redoxin ERp29_N PF07912.13 EPS31260.1 - 5.2e-05 23.4 0.4 0.27 11.4 0.0 3.9 4 0 0 4 4 4 2 ERp29, N-terminal domain Thioredoxin_4 PF13462.6 EPS31260.1 - 0.11 12.7 0.1 0.11 12.7 0.1 3.6 4 2 0 4 4 4 0 Thioredoxin ATG22 PF11700.8 EPS31262.1 - 1e-204 680.6 8.9 1.2e-204 680.4 8.9 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 EPS31262.1 - 1.5e-07 30.6 19.3 1.5e-07 30.6 19.3 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Pkinase PF00069.25 EPS31263.1 - 9.2e-11 41.6 0.0 1.2e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EPS31263.1 - 3.4e-06 27.1 0.0 5.1e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EPS31263.1 - 2e-05 24.0 0.0 2.6e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EPS31263.1 - 0.00025 20.5 0.0 0.00038 19.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EPS31263.1 - 0.00093 18.8 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 EPS31263.1 - 0.0052 16.4 0.0 0.0077 15.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.6 EPS31263.1 - 0.036 13.4 0.0 0.055 12.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 EPS31263.1 - 0.088 11.6 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Med14 PF08638.11 EPS31264.1 - 3.6e-64 215.7 0.0 5.6e-64 215.1 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit MED14 DNA_pol_E_B PF04042.16 EPS31265.1 - 1.1e-50 171.9 0.1 1.5e-50 171.5 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B SLAIN PF15301.6 EPS31265.1 - 1.4 8.1 3.9 0.51 9.5 1.0 1.7 2 0 0 2 2 2 0 SLAIN motif-containing family SHNi-TPR PF10516.9 EPS31266.1 - 3.5e-15 55.2 1.6 5e-15 54.7 0.1 2.1 2 0 0 2 2 2 1 SHNi-TPR TPR_11 PF13414.6 EPS31266.1 - 0.0035 17.0 2.5 11 5.9 0.1 3.9 4 0 0 4 4 4 1 TPR repeat DUF3232 PF11554.8 EPS31266.1 - 0.012 15.9 2.2 0.03 14.7 2.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3232) MIT PF04212.18 EPS31266.1 - 0.44 10.7 5.6 0.099 12.7 1.1 2.3 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain GREB1 PF15782.5 EPS31266.1 - 7 3.6 13.6 13 2.8 13.6 1.3 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Yippee-Mis18 PF03226.14 EPS31267.1 - 4.7e-21 75.0 0.2 6.9e-21 74.4 0.2 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Transp_Tc5_C PF04236.15 EPS31267.1 - 0.048 14.0 1.2 0.16 12.3 0.4 2.0 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain RIG-I_C-RD PF11648.8 EPS31267.1 - 0.18 12.1 0.8 4.4 7.6 0.0 2.2 2 0 0 2 2 2 0 C-terminal domain of RIG-I Ribosomal_S27e PF01667.17 EPS31267.1 - 0.8 9.5 4.0 3.9 7.2 0.9 2.3 2 0 0 2 2 2 0 Ribosomal protein S27 AgrB PF04647.15 EPS31267.1 - 9.1 5.5 6.3 14 4.9 0.1 2.1 2 0 0 2 2 2 0 Accessory gene regulator B ODC_AZ PF02100.17 EPS31268.1 - 9e-38 128.8 0.0 1.3e-37 128.2 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme DWNN PF08783.11 EPS31269.1 - 3.7e-33 113.6 0.1 1.3e-32 111.9 0.1 1.9 2 0 0 2 2 2 1 DWNN domain zf-CCHC_2 PF13696.6 EPS31269.1 - 3.7e-08 33.0 5.0 6.7e-08 32.2 5.0 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EPS31269.1 - 0.002 18.1 0.7 0.0043 17.1 0.7 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.6 EPS31269.1 - 0.0026 17.6 8.2 0.0052 16.6 8.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EPS31269.1 - 0.33 10.8 5.8 0.79 9.6 5.8 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 EPS31269.1 - 0.35 11.2 6.9 0.75 10.2 6.9 1.6 1 0 0 1 1 1 0 Ring finger domain zf-Nse PF11789.8 EPS31269.1 - 0.4 10.5 4.1 0.84 9.5 4.1 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF3987 PF13148.6 EPS31269.1 - 1.8 7.5 6.3 1.2 8.1 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) zf-RING_5 PF14634.6 EPS31269.1 - 3.7 7.6 11.1 0.22 11.5 4.9 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.25 EPS31269.1 - 3.8 7.5 8.2 8.2 6.4 8.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EPS31269.1 - 4.3 7.6 9.3 11 6.3 9.3 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF2654 PF10849.8 EPS31270.1 - 0.055 13.7 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2654) His_biosynth PF00977.21 EPS31271.1 - 1e-46 159.3 0.5 2.4e-46 158.0 0.5 1.7 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 EPS31271.1 - 1.7e-21 76.8 0.0 2.7e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 EPS31271.1 - 2.6e-10 40.4 0.0 1.1e-08 35.2 0.0 2.3 2 0 0 2 2 2 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 EPS31271.1 - 4.3e-08 33.0 0.0 9.3e-08 31.9 0.0 1.5 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 EPS31271.1 - 0.0006 19.6 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 NMO PF03060.15 EPS31271.1 - 0.052 12.9 0.8 0.17 11.2 0.2 1.9 2 0 0 2 2 2 0 Nitronate monooxygenase dCMP_cyt_deam_1 PF00383.23 EPS31272.1 - 4.3e-28 97.2 0.5 7.2e-28 96.4 0.5 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EPS31272.1 - 4.3e-11 42.7 0.1 7.6e-11 41.9 0.1 1.4 1 0 0 1 1 1 1 MafB19-like deaminase CoaE PF01121.20 EPS31272.1 - 0.011 15.4 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA_18 PF13238.6 EPS31272.1 - 0.02 15.4 0.0 0.14 12.7 0.0 2.3 1 1 0 1 1 1 0 AAA domain ATG7_N PF16420.5 EPS31273.1 - 4.4e-108 361.5 0.0 5.8e-108 361.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 EPS31273.1 - 3.6e-45 154.2 0.0 5.2e-45 153.7 0.0 1.1 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 EPS31273.1 - 0.0072 16.4 0.2 0.032 14.3 0.0 2.0 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Flagellin_C PF00700.21 EPS31273.1 - 0.027 14.8 0.2 0.057 13.8 0.2 1.4 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region 2-Hacid_dh_C PF02826.19 EPS31273.1 - 0.073 12.4 0.0 0.38 10.1 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FtsJ PF01728.19 EPS31274.1 - 5.3e-55 186.3 0.0 6.2e-55 186.0 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 EPS31274.1 - 0.003 17.4 0.0 0.0081 16.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPS31274.1 - 0.084 12.7 0.0 4.9 6.9 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 EPS31274.1 - 0.15 12.8 0.0 1.2 9.9 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain OST3_OST6 PF04756.13 EPS31276.1 - 3.5e-105 351.6 0.0 4e-105 351.3 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 EPS31276.1 - 0.004 17.1 0.0 0.01 15.8 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin DUF2649 PF10854.8 EPS31276.1 - 0.089 13.1 0.1 0.25 11.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2649) HXXEE PF13787.6 EPS31276.1 - 2.6 8.9 7.1 0.33 11.8 1.0 2.2 1 1 0 2 2 2 0 Protein of unknown function with HXXEE motif Fig1 PF12351.8 EPS31276.1 - 9.1 6.2 8.5 2.6 7.9 0.5 2.2 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Rft-1 PF04506.13 EPS31277.1 - 3.9e-142 474.6 12.6 4.3e-142 474.5 12.6 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt PF01943.17 EPS31277.1 - 2.5e-08 33.7 3.7 2.5e-08 33.7 3.7 3.3 3 1 1 4 4 4 2 Polysaccharide biosynthesis protein DEAD PF00270.29 EPS31278.1 - 6.9e-48 162.7 0.0 1.5e-47 161.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPS31278.1 - 1.9e-29 102.2 0.0 7.6e-29 100.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPS31278.1 - 8.1e-09 35.7 0.3 7.8e-08 32.5 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EPS31278.1 - 6.2e-06 25.7 9.3 0.0055 16.1 0.0 2.5 2 0 0 2 2 2 2 U3-containing 90S pre-ribosomal complex subunit DUF4887 PF16228.5 EPS31278.1 - 0.02 15.1 10.3 0.034 14.3 10.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) DUF1687 PF07955.11 EPS31278.1 - 0.39 11.2 4.9 10 6.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1687) Peptidase_S49_N PF08496.10 EPS31278.1 - 4.4 7.3 7.6 8.9 6.4 7.6 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CPSF100_C PF13299.6 EPS31278.1 - 9.2 6.4 9.5 51 4.0 7.4 2.5 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal Rep_fac-A_C PF08646.10 EPS31279.1 - 2.1e-53 180.0 2.1 6.7e-52 175.1 1.1 2.4 2 0 0 2 2 2 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 EPS31279.1 - 1.3e-35 121.2 0.1 4.9e-35 119.4 0.1 2.0 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 EPS31279.1 - 1.7e-22 79.3 0.0 4.1e-22 78.1 0.0 1.7 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 EPS31279.1 - 1.1e-12 47.7 0.0 1.1e-07 31.7 0.0 3.5 3 0 0 3 3 3 2 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 EPS31279.1 - 0.0019 18.0 0.3 0.011 15.5 0.2 2.2 3 0 0 3 3 3 1 Cell division control protein 24, OB domain 3 DUF4503 PF14951.6 EPS31279.1 - 0.084 11.3 0.1 0.13 10.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) UCH PF00443.29 EPS31280.1 - 6.6e-38 130.7 0.0 9e-38 130.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 EPS31280.1 - 1.9e-25 88.4 1.4 7.1e-24 83.3 0.1 2.5 2 0 0 2 2 2 1 Variant UBP zinc finger zf-UBP PF02148.19 EPS31280.1 - 2.1e-23 82.4 17.0 2.4e-19 69.4 2.7 3.1 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.31 EPS31280.1 - 1.4e-21 76.0 0.1 1.7e-10 40.6 0.0 2.7 3 0 0 3 3 3 2 UBA/TS-N domain UCH_1 PF13423.6 EPS31280.1 - 1.3e-16 61.1 2.0 2.6e-15 56.8 1.0 3.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.6 EPS31280.1 - 0.0022 17.8 0.0 0.005 16.6 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain zf-RING_UBOX PF13445.6 EPS31280.1 - 0.63 10.1 6.0 18 5.5 2.2 3.6 3 0 0 3 3 3 0 RING-type zinc-finger TerY_C PF15616.6 EPS31280.1 - 2 8.6 6.3 3.2 7.9 0.2 2.8 2 0 0 2 2 2 0 TerY-C metal binding domain SH3BGR PF04908.15 EPS31281.1 - 0.013 15.6 0.7 0.023 14.9 0.7 1.3 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein Ank_2 PF12796.7 EPS31282.1 - 1.3e-12 48.1 0.0 8.9e-06 26.2 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EPS31282.1 - 3.3e-12 46.4 0.2 4.2e-05 23.7 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EPS31282.1 - 9.7e-11 41.6 0.0 0.19 12.2 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EPS31282.1 - 3.2e-09 36.3 0.0 0.0081 16.6 0.0 4.4 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.6 EPS31282.1 - 1.3e-08 35.2 0.1 0.049 14.2 0.0 3.9 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Zn_clus PF00172.18 EPS31283.1 - 3.8e-07 30.1 7.1 3.8e-07 30.1 7.1 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EPS31283.1 - 3.5e-06 26.1 0.0 7.5e-06 25.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4327 PF14217.6 EPS31283.1 - 0.094 12.9 0.1 0.23 11.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4327) RTA1 PF04479.13 EPS31284.1 - 2.1e-40 138.6 6.4 1.9e-37 128.9 6.4 2.0 1 1 0 1 1 1 1 RTA1 like protein HCO3_cotransp PF00955.21 EPS31285.1 - 8.8e-73 245.9 10.7 2.8e-40 138.6 6.8 2.1 1 1 1 2 2 2 2 HCO3- transporter family SET PF00856.28 EPS31287.1 - 1.4e-09 38.5 0.1 6.6e-09 36.4 0.1 1.9 1 1 0 1 1 1 1 SET domain Innate_immun PF12782.7 EPS31290.1 - 0.069 12.6 0.2 0.087 12.3 0.2 1.1 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family TPR_10 PF13374.6 EPS31291.1 - 1.8e-77 253.3 4.5 3.5e-12 45.8 0.0 7.7 7 1 0 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.6 EPS31291.1 - 1.8e-72 239.6 15.4 1.4e-15 57.3 0.1 6.8 2 1 5 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.6 EPS31291.1 - 1.5e-27 93.6 0.8 0.00037 20.3 0.0 6.3 6 0 0 6 6 6 6 Tetratricopeptide repeat Ank PF00023.30 EPS31291.1 - 1.3e-26 91.8 1.7 0.00061 20.1 0.0 5.8 6 0 0 6 6 5 5 Ankyrin repeat Ank_2 PF12796.7 EPS31291.1 - 1.1e-24 86.8 0.0 2.3e-11 44.1 0.0 4.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) TPR_16 PF13432.6 EPS31291.1 - 5.7e-23 81.3 0.0 0.073 13.7 0.0 6.4 4 1 2 6 6 6 6 Tetratricopeptide repeat TPR_2 PF07719.17 EPS31291.1 - 6.2e-23 79.0 0.2 0.0052 16.8 0.0 6.4 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.28 EPS31291.1 - 9e-22 75.9 2.5 0.056 13.3 0.0 6.4 6 0 0 6 6 6 6 Tetratricopeptide repeat Ank_5 PF13857.6 EPS31291.1 - 5.8e-21 74.3 0.1 0.00075 19.7 0.0 5.5 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPS31291.1 - 1.1e-20 71.5 0.0 0.0041 17.5 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat TPR_4 PF07721.14 EPS31291.1 - 3.6e-20 70.5 0.0 0.12 13.1 0.0 6.6 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_17 PF13431.6 EPS31291.1 - 2.1e-18 65.3 4.3 0.093 13.2 0.1 6.4 6 0 0 6 6 6 5 Tetratricopeptide repeat Ank_4 PF13637.6 EPS31291.1 - 2.2e-18 66.3 0.0 2.7e-06 27.8 0.0 4.3 2 2 3 5 5 5 4 Ankyrin repeats (many copies) TPR_19 PF14559.6 EPS31291.1 - 1e-17 64.4 0.3 0.25 11.9 0.0 6.4 3 2 3 6 6 6 6 Tetratricopeptide repeat PPR PF01535.20 EPS31291.1 - 1.2e-11 44.0 3.2 2.4 8.6 0.0 6.5 6 0 0 6 6 6 3 PPR repeat TPR_MalT PF17874.1 EPS31291.1 - 5.3e-11 42.5 7.2 2.2e-07 30.6 4.8 2.6 1 1 1 2 2 2 2 MalT-like TPR region ANAPC3 PF12895.7 EPS31291.1 - 2e-09 37.6 0.6 0.027 14.7 0.0 5.7 1 1 5 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 EPS31291.1 - 1.1e-08 34.6 8.1 0.26 11.6 0.1 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_20 PF14561.6 EPS31291.1 - 5.5e-08 33.0 0.4 22 5.5 0.0 6.2 1 1 5 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 EPS31291.1 - 1.5e-07 31.7 1.2 55 5.0 0.0 6.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 EPS31291.1 - 2.6e-05 24.6 9.7 1.2 9.9 0.0 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat Rapsyn_N PF10579.9 EPS31291.1 - 7.3e-05 22.8 0.5 0.85 9.8 0.1 4.3 2 1 2 4 4 4 1 Rapsyn N-terminal myristoylation and linker region A2M PF00207.22 EPS31291.1 - 0.00045 20.0 4.4 3.4 7.6 0.1 4.8 1 1 5 6 6 6 1 Alpha-2-macroglobulin family PPR_1 PF12854.7 EPS31291.1 - 0.0015 18.2 0.0 37 4.1 0.0 5.5 6 0 0 6 6 6 0 PPR repeat BTAD PF03704.17 EPS31291.1 - 0.002 18.6 1.2 6.5 7.2 0.0 3.9 1 1 1 3 3 3 0 Bacterial transcriptional activator domain PPR_2 PF13041.6 EPS31291.1 - 0.003 17.7 3.3 42 4.5 0.0 5.5 6 0 0 6 6 6 0 PPR repeat family SnoaL_4 PF13577.6 EPS31291.1 - 0.0034 17.5 1.7 0.46 10.6 0.6 3.4 1 1 2 3 3 3 1 SnoaL-like domain TPR_11 PF13414.6 EPS31291.1 - 0.0055 16.4 3.2 1.7 8.4 0.1 4.9 6 0 0 6 6 6 1 TPR repeat RPN6_N PF18055.1 EPS31291.1 - 0.014 15.7 3.3 10 6.5 0.1 3.4 1 1 4 5 5 5 0 26S proteasome regulatory subunit RPN6 N-terminal domain Spore_YpjB PF09577.10 EPS31291.1 - 0.051 13.4 3.6 12 5.6 0.1 3.4 3 1 1 4 4 4 0 Sporulation protein YpjB (SpoYpjB) TPR_3 PF07720.12 EPS31291.1 - 0.07 13.1 0.0 12 6.0 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3435 PF11917.8 EPS31294.1 - 1.1e-38 133.3 1.6 4.2e-17 62.2 0.1 3.0 1 1 2 3 3 3 3 Protein of unknown function (DUF3435) RVT_2 PF07727.14 EPS31296.1 - 6.3e-17 62.0 0.0 9.1e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 EPS31297.1 - 5.9e-13 49.1 0.0 1.7e-12 47.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 EPS31297.1 - 0.0042 16.9 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain RAMP4 PF06624.12 EPS31298.1 - 3.1e-23 81.6 0.0 3.6e-23 81.4 0.0 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 MarC PF01914.17 EPS31298.1 - 0.055 12.9 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 MarC family integral membrane protein Adaptin_N PF01602.20 EPS31299.1 - 2.6e-87 293.6 0.0 3.1e-86 290.0 0.0 2.1 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EPS31299.1 - 2.4e-06 27.7 0.0 0.00045 20.3 0.0 2.5 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EPS31299.1 - 6.4e-06 26.0 1.9 0.15 12.4 0.0 5.0 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.6 EPS31299.1 - 0.0001 22.6 4.0 0.58 10.6 0.4 3.9 3 0 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 EPS31299.1 - 0.0089 16.5 5.1 11 6.7 0.1 4.7 4 0 0 4 4 4 1 HEAT-like repeat TPR_17 PF13431.6 EPS31300.1 - 3.9e-07 30.0 0.0 0.17 12.3 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EPS31300.1 - 2.2e-06 28.1 10.5 0.00011 22.7 0.8 4.1 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EPS31300.1 - 6.2e-06 26.0 0.5 0.0062 16.7 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EPS31300.1 - 6.5e-06 26.5 11.8 0.018 15.8 0.1 5.4 5 2 2 7 7 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 EPS31300.1 - 0.00013 21.6 0.3 1.5 8.6 0.0 3.7 4 0 0 4 4 4 2 TPR repeat TPR_1 PF00515.28 EPS31300.1 - 0.00048 19.8 0.4 0.012 15.4 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 EPS31300.1 - 0.00096 19.3 1.0 0.00096 19.3 1.0 2.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EPS31300.1 - 0.0016 18.4 6.2 0.036 14.2 0.0 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat SRP54_N PF02881.19 EPS31300.1 - 0.061 13.5 0.0 0.19 12.0 0.0 1.8 1 0 0 1 1 1 0 SRP54-type protein, helical bundle domain Wzy_C_2 PF11846.8 EPS31300.1 - 0.066 13.1 1.6 2.6 7.9 0.2 2.9 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal DUF4704 PF15787.5 EPS31300.1 - 0.17 11.1 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4704) TPR_12 PF13424.6 EPS31300.1 - 0.21 11.9 5.8 0.95 9.8 0.5 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EPS31300.1 - 0.32 11.7 2.7 41 5.1 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat AAA_11 PF13086.6 EPS31302.1 - 0.059 13.1 12.3 0.1 12.4 12.3 1.2 1 0 0 1 1 1 0 AAA domain U79_P34 PF03064.16 EPS31302.1 - 0.18 11.1 2.2 0.49 9.7 2.2 1.7 1 0 0 1 1 1 0 HSV U79 / HCMV P34 TFIIA PF03153.13 EPS31302.1 - 0.25 11.3 10.8 0.63 10.0 10.8 1.7 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Syja_N PF02383.18 EPS31303.1 - 6.7e-75 252.4 0.0 9e-75 251.9 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 EPS31303.1 - 2.1e-10 40.5 0.1 4.1e-10 39.6 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family G-patch PF01585.23 EPS31304.1 - 2.3e-05 24.2 0.0 0.00021 21.1 0.0 2.3 1 1 0 1 1 1 1 G-patch domain SRP-alpha_N PF04086.13 EPS31304.1 - 0.0023 17.9 22.4 0.0032 17.4 22.4 1.3 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal TFIIF_alpha PF05793.12 EPS31304.1 - 0.022 13.4 32.5 0.029 13.0 32.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF572 PF04502.13 EPS31304.1 - 0.042 13.5 22.3 0.059 13.0 22.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Apt1 PF10351.9 EPS31304.1 - 0.054 12.4 21.6 0.067 12.0 21.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC45 PF02724.14 EPS31304.1 - 0.11 10.8 23.1 0.15 10.3 23.1 1.2 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.11 EPS31304.1 - 0.12 12.0 21.8 0.17 11.4 21.8 1.2 1 0 0 1 1 1 0 PPP4R2 Macoilin PF09726.9 EPS31304.1 - 0.14 10.7 17.1 0.16 10.5 17.1 1.1 1 0 0 1 1 1 0 Macoilin family SAPS PF04499.15 EPS31304.1 - 0.19 10.5 13.2 0.24 10.1 13.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein RR_TM4-6 PF06459.12 EPS31304.1 - 0.41 10.4 19.3 0.67 9.7 19.3 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Raftlin PF15250.6 EPS31304.1 - 0.47 9.2 12.1 0.57 8.9 12.1 1.1 1 0 0 1 1 1 0 Raftlin GREB1 PF15782.5 EPS31304.1 - 0.48 7.5 13.4 0.55 7.3 13.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer G-patch_2 PF12656.7 EPS31304.1 - 0.68 10.1 0.0 0.68 10.1 0.0 3.1 2 1 0 2 2 1 0 G-patch domain FAM60A PF15396.6 EPS31304.1 - 1.1 9.2 18.9 1.8 8.5 18.9 1.3 1 0 0 1 1 1 0 Protein Family FAM60A NPR3 PF03666.13 EPS31304.1 - 1.3 7.7 23.1 1.8 7.3 23.1 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FancD2 PF14631.6 EPS31304.1 - 1.9 5.8 15.1 2.3 5.5 15.1 1.1 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease Bud13 PF09736.9 EPS31304.1 - 2.3 8.6 20.7 0.74 10.2 17.9 1.7 2 0 0 2 2 1 0 Pre-mRNA-splicing factor of RES complex SLC12 PF03522.15 EPS31304.1 - 3.1 6.7 18.0 4.3 6.2 18.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF4551 PF15087.6 EPS31304.1 - 3.2 6.5 13.8 3.8 6.2 13.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) ORC6 PF05460.13 EPS31304.1 - 3.2 6.9 23.0 4.6 6.4 23.0 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Presenilin PF01080.17 EPS31304.1 - 3.8 6.2 22.4 5.2 5.7 22.4 1.1 1 0 0 1 1 1 0 Presenilin Menin PF05053.13 EPS31304.1 - 4.9 5.4 13.2 6.2 5.1 13.2 1.2 1 0 0 1 1 1 0 Menin SOBP PF15279.6 EPS31304.1 - 6.1 7.3 18.2 8.7 6.9 18.2 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Paramyxo_ncap PF00973.19 EPS31304.1 - 6.8 5.5 10.6 8.3 5.2 10.6 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Dsh_C PF12316.8 EPS31304.1 - 7.7 6.9 21.5 13 6.1 21.5 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal NOA36 PF06524.12 EPS31304.1 - 9.1 5.5 17.1 13 5.0 17.1 1.1 1 0 0 1 1 1 0 NOA36 protein DAGAT PF03982.13 EPS31305.1 - 2.6e-91 305.7 0.0 3.2e-91 305.3 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DUF4020 PF13212.6 EPS31305.1 - 0.098 12.5 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4020) Rer1 PF03248.13 EPS31305.1 - 0.19 11.5 6.5 0.21 11.3 5.3 1.5 1 1 0 1 1 1 0 Rer1 family Kinesin PF00225.23 EPS31306.1 - 1.6e-95 319.8 0.0 2.9e-95 319.0 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EPS31306.1 - 4.4e-22 78.6 0.0 9e-22 77.6 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding PKcGMP_CC PF16808.5 EPS31306.1 - 0.00038 20.2 4.6 0.0066 16.3 0.9 3.9 4 0 0 4 4 4 1 Coiled-coil N-terminus of cGMP-dependent protein kinase Lebercilin PF15619.6 EPS31306.1 - 0.0044 16.7 2.4 0.0044 16.7 2.4 2.9 2 1 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease Lzipper-MIP1 PF14389.6 EPS31306.1 - 0.25 11.7 11.2 1.8 8.9 0.5 3.6 2 2 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 DUF1627 PF07789.12 EPS31306.1 - 0.68 9.6 3.2 15 5.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1627) XLF PF09302.11 EPS31306.1 - 0.84 9.8 4.3 15 5.7 0.2 3.2 3 0 0 3 3 3 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component DUF2205 PF10224.9 EPS31306.1 - 6.7 6.8 7.4 8.9 6.4 2.7 2.9 3 0 0 3 3 3 0 Short coiled-coil protein Pkinase PF00069.25 EPS31308.1 - 3e-63 213.6 0.0 3.6e-63 213.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS31308.1 - 3.9e-34 118.1 0.0 5.2e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EPS31308.1 - 0.0019 17.6 0.0 0.0087 15.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EPS31308.1 - 0.11 12.3 0.1 0.59 10.0 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family IGR PF09597.10 EPS31309.1 - 8.6e-24 83.4 0.4 1.6e-23 82.6 0.4 1.5 1 0 0 1 1 1 1 IGR protein motif p450 PF00067.22 EPS31310.1 - 3.1e-73 247.1 0.0 3.8e-73 246.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 EPS31312.1 - 2.4e-77 259.9 0.0 3.2e-77 259.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS31312.1 - 1.8e-36 125.8 0.0 2.6e-36 125.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EPS31312.1 - 4.2e-15 55.9 0.1 9e-15 54.8 0.1 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 EPS31312.1 - 3.8e-10 39.6 0.0 2.7e-08 33.5 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Yop-YscD_cpl PF16697.5 EPS31312.1 - 2.5e-06 27.7 0.0 5.4e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Pkinase_fungal PF17667.1 EPS31312.1 - 2.6e-06 26.5 0.0 4.6e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EPS31312.1 - 0.00068 19.6 0.2 0.0036 17.2 0.2 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EPS31312.1 - 0.0074 15.7 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EPS31312.1 - 0.014 15.0 0.0 0.49 10.0 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 EPS31312.1 - 0.077 12.5 0.0 0.18 11.3 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Haspin_kinase PF12330.8 EPS31312.1 - 0.2 10.6 0.1 0.31 9.9 0.1 1.2 1 0 0 1 1 1 0 Haspin like kinase domain PI3_PI4_kinase PF00454.27 EPS31313.1 - 7.8e-38 130.7 0.0 1.5e-35 123.2 0.0 2.4 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EPS31313.1 - 1.9e-24 86.1 0.0 4.4e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) LRR_6 PF13516.6 EPS31314.1 - 3.3e-05 23.6 4.0 5.5 7.3 0.0 5.8 6 0 0 6 6 6 3 Leucine Rich repeat DUF4428 PF14471.6 EPS31314.1 - 0.079 12.9 0.8 0.22 11.5 0.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) Zn_ribbon_recom PF13408.6 EPS31314.1 - 0.2 12.2 1.7 3.6 8.2 0.7 2.4 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain SNF2_N PF00176.23 EPS31315.1 - 1e-51 175.7 0.3 3e-50 170.9 0.1 2.6 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EPS31315.1 - 1.7e-16 60.5 0.0 6.7e-16 58.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPS31315.1 - 3.9e-08 33.5 0.0 1.1e-07 32.0 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 EPS31315.1 - 1.3e-06 28.2 6.9 1.3e-06 28.2 6.9 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 EPS31315.1 - 0.00027 20.8 0.0 0.00061 19.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_3 PF13920.6 EPS31315.1 - 0.00055 19.7 6.8 0.00055 19.7 6.8 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) AAA_34 PF13872.6 EPS31315.1 - 0.0014 17.6 0.0 0.0032 16.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 zf-C3HC4_2 PF13923.6 EPS31315.1 - 0.0022 17.8 6.7 0.0022 17.8 6.7 2.6 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EPS31315.1 - 0.0051 16.9 6.2 0.0051 16.9 6.2 2.4 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 EPS31315.1 - 0.0063 16.8 8.0 0.0063 16.8 8.0 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 EPS31315.1 - 0.013 15.5 3.2 0.013 15.5 3.2 2.8 2 1 0 2 2 2 0 RING-type zinc-finger Zn_Tnp_IS91 PF14319.6 EPS31315.1 - 0.3 11.1 14.6 0.026 14.5 2.6 2.6 2 0 0 2 2 2 0 Transposase zinc-binding domain DUF778 PF05608.12 EPS31315.1 - 5.8 7.2 5.8 6.7 7.0 0.2 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF778) C2 PF00168.30 EPS31316.1 - 5.2e-10 39.5 0.0 1e-09 38.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain DUF4122 PF13498.6 EPS31316.1 - 0.072 12.8 0.2 0.13 12.0 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4122) ArfGap PF01412.18 EPS31319.1 - 1.3e-32 112.3 0.0 1.3e-32 112.3 0.0 2.6 4 0 0 4 4 4 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 EPS31319.1 - 3.2e-23 82.7 19.6 5.4e-23 81.9 19.6 1.2 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 EPS31319.1 - 1.3e-11 44.9 2.0 1.4e-11 44.8 0.2 2.0 2 0 0 2 2 2 1 PH domain TF_Zn_Ribbon PF08271.12 EPS31319.1 - 0.22 11.1 0.0 0.53 9.9 0.0 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding YTH PF04146.15 EPS31321.1 - 9.9e-60 201.2 0.0 1.6e-59 200.5 0.0 1.4 1 0 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.22 EPS31321.1 - 2.1e-07 30.7 0.0 3.8e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1970 PF09301.10 EPS31321.1 - 0.0057 16.9 0.3 0.018 15.3 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1970) Cytomega_UL20A PF05984.12 EPS31321.1 - 0.054 13.8 0.5 0.17 12.2 0.5 1.9 1 0 0 1 1 1 0 Cytomegalovirus UL20A protein RRM_occluded PF16842.5 EPS31321.1 - 0.083 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif APH PF01636.23 EPS31325.1 - 6.3e-08 32.8 0.0 1.5e-06 28.4 0.0 2.0 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pirin PF02678.16 EPS31326.1 - 7e-31 106.4 0.1 1.6e-30 105.2 0.1 1.6 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 EPS31326.1 - 5.8e-25 87.6 0.0 3.5e-24 85.1 0.0 2.1 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 EPS31326.1 - 1.4e-05 24.7 3.1 6.9e-05 22.5 1.1 2.4 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.12 EPS31326.1 - 0.12 12.1 0.0 0.53 10.0 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF861) PRKCSH PF07915.13 EPS31327.1 - 6.2e-20 72.0 0.3 6.2e-20 72.0 0.3 2.3 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 EPS31327.1 - 0.017 14.8 0.1 0.055 13.2 0.1 1.9 1 1 0 1 1 1 0 Glucosidase II beta subunit-like protein YolD PF08863.10 EPS31327.1 - 0.11 12.6 0.4 0.52 10.4 0.3 2.1 1 1 1 2 2 2 0 YolD-like protein CDC45 PF02724.14 EPS31327.1 - 8.7 4.5 8.2 13 3.9 8.2 1.2 1 0 0 1 1 1 0 CDC45-like protein SHD1 PF03983.12 EPS31328.1 - 3.8e-33 113.1 0.1 6.5e-33 112.4 0.1 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.28 EPS31328.1 - 1.5e-32 111.0 6.6 6.1e-12 45.0 0.0 4.3 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.6 EPS31328.1 - 4.4e-29 100.1 8.0 4.5e-11 42.4 0.3 3.9 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.17 EPS31328.1 - 1.3e-22 79.2 0.4 5.7e-07 29.1 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain SH3_10 PF17902.1 EPS31328.1 - 0.00015 21.8 0.1 0.48 10.5 0.0 3.9 4 0 0 4 4 4 1 SH3 domain SAM_4 PF18017.1 EPS31328.1 - 0.00017 21.5 0.0 0.00067 19.6 0.0 1.9 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SH3_3 PF08239.11 EPS31328.1 - 0.00064 20.0 3.7 0.079 13.3 0.3 3.0 3 0 0 3 3 3 2 Bacterial SH3 domain DUF1720 PF08226.11 EPS31328.1 - 0.0019 18.6 50.0 0.0019 18.6 50.0 7.0 2 1 4 7 7 7 4 Domain of unknown function (DUF1720) SAM_1 PF00536.30 EPS31328.1 - 0.19 12.2 0.0 0.37 11.2 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) PAP2_3 PF14378.6 EPS31330.1 - 8.1e-34 117.0 16.6 2.1e-16 60.2 0.1 3.5 4 0 0 4 4 4 3 PAP2 superfamily PAP2 PF01569.21 EPS31330.1 - 0.019 14.8 0.8 0.019 14.8 0.8 2.7 2 1 1 3 3 3 0 PAP2 superfamily PWWP PF00855.17 EPS31331.1 - 8.4e-15 55.0 0.0 8.4e-15 55.0 0.0 4.1 2 1 0 3 3 3 1 PWWP domain SpoIIE PF07228.12 EPS31332.1 - 3.5e-11 43.4 0.1 8.1e-11 42.2 0.1 1.6 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 EPS31332.1 - 1.4e-07 31.4 0.0 0.0037 16.9 0.1 2.4 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 EPS31332.1 - 9.7e-07 28.6 0.1 2.4e-06 27.4 0.1 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C WD40 PF00400.32 EPS31333.1 - 6.4e-32 109.1 20.0 6.1e-07 30.0 0.1 7.7 8 0 0 8 8 8 5 WD domain, G-beta repeat PRP4 PF08799.11 EPS31333.1 - 2.7e-13 49.2 6.0 2.7e-13 49.2 6.0 1.8 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 EPS31333.1 - 2.4e-09 37.3 0.0 0.014 15.7 0.0 5.0 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EPS31333.1 - 0.063 12.6 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 WD40-like domain HSCB_C PF07743.13 EPS31334.1 - 4.3e-20 72.0 0.2 8.9e-19 67.8 0.0 2.2 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 EPS31334.1 - 3.1e-07 30.4 0.0 6.7e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain SLAC1 PF03595.17 EPS31338.1 - 2.1e-86 290.1 38.6 2.5e-86 289.9 38.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel RTC_insert PF05189.13 EPS31339.1 - 7.5e-29 100.3 0.0 1.3e-28 99.6 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.21 EPS31339.1 - 1.9e-25 89.4 0.0 2.3e-25 89.1 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase 3-HAO PF06052.12 EPS31340.1 - 2e-55 186.6 0.0 2.4e-55 186.3 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 EPS31340.1 - 0.00033 20.3 0.0 0.00053 19.6 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 EPS31340.1 - 0.00065 19.3 0.1 0.001 18.7 0.1 1.3 1 0 0 1 1 1 1 Cupin DZR PF12773.7 EPS31340.1 - 0.0024 17.8 1.8 0.0054 16.7 1.8 1.6 1 0 0 1 1 1 1 Double zinc ribbon AraC_binding PF02311.19 EPS31340.1 - 0.1 12.5 0.1 0.16 11.9 0.1 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain FYVE PF01363.21 EPS31340.1 - 0.38 10.9 3.8 0.82 9.9 3.8 1.6 1 1 0 1 1 1 0 FYVE zinc finger Rubredoxin_2 PF18073.1 EPS31340.1 - 0.93 9.3 5.1 9.2 6.1 0.5 2.5 2 0 0 2 2 2 0 Rubredoxin metal binding domain Zn-ribbon_8 PF09723.10 EPS31340.1 - 2.7 8.2 7.1 0.26 11.4 0.4 2.5 3 0 0 3 3 3 0 Zinc ribbon domain CAP_GLY PF01302.25 EPS31342.1 - 6.3e-15 54.9 0.6 1.1e-14 54.1 0.6 1.4 1 0 0 1 1 1 1 CAP-Gly domain CLIP1_ZNF PF16641.5 EPS31342.1 - 6.7e-11 41.8 10.7 4.7e-05 23.2 0.9 2.5 2 0 0 2 2 2 2 CLIP1 zinc knuckle FAM76 PF16046.5 EPS31342.1 - 0.00069 19.1 3.2 0.00069 19.1 3.2 2.9 2 2 1 3 3 3 1 FAM76 protein DUF812 PF05667.11 EPS31342.1 - 0.0063 15.5 15.4 0.0063 15.5 15.4 3.2 1 1 2 3 3 3 2 Protein of unknown function (DUF812) Fez1 PF06818.15 EPS31342.1 - 0.028 14.9 47.3 0.099 13.1 18.4 3.3 1 1 2 3 3 3 0 Fez1 YPEB PF14620.6 EPS31342.1 - 0.1 11.9 19.5 0.22 10.8 1.4 2.8 2 1 1 3 3 3 0 YpeB sporulation YajC PF02699.15 EPS31342.1 - 0.25 11.2 0.1 0.25 11.2 0.1 2.5 3 0 0 3 3 3 0 Preprotein translocase subunit Pox_A_type_inc PF04508.12 EPS31342.1 - 0.38 10.7 21.6 0.38 10.7 2.6 4.8 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat DUF1664 PF07889.12 EPS31342.1 - 0.67 10.0 26.4 0.33 11.0 3.1 3.8 1 1 2 4 4 4 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.12 EPS31342.1 - 0.88 10.1 15.6 2.6 8.6 0.7 3.8 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein EzrA PF06160.12 EPS31342.1 - 1.2 7.3 31.2 0.64 8.1 10.1 3.3 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA AAA_13 PF13166.6 EPS31342.1 - 1.5 7.4 33.3 0.16 10.6 14.7 2.6 1 1 0 2 2 2 0 AAA domain Phage_GP20 PF06810.11 EPS31342.1 - 2.4 8.0 30.2 1.6 8.5 3.2 3.5 2 1 1 3 3 3 0 Phage minor structural protein GP20 Tnp_22_trimer PF17489.2 EPS31342.1 - 2.5 8.1 10.1 0.83 9.7 3.2 3.0 2 0 0 2 2 2 0 L1 transposable element trimerization domain Spc7 PF08317.11 EPS31342.1 - 2.8 6.7 48.5 0.16 10.8 10.0 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein BLOC1_2 PF10046.9 EPS31342.1 - 4.3 7.7 29.9 0.57 10.5 4.6 4.1 3 1 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tropomyosin PF00261.20 EPS31342.1 - 4.7 6.5 48.3 0.084 12.2 4.9 3.2 2 1 1 3 3 3 0 Tropomyosin DUF4407 PF14362.6 EPS31342.1 - 7 5.9 36.0 2.1 7.6 12.8 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) Cauli_AT PF03233.13 EPS31342.1 - 9.1 6.2 16.5 10 6.0 1.9 3.4 2 1 1 3 3 3 0 Aphid transmission protein Pkinase PF00069.25 EPS31343.1 - 2.7e-37 128.6 0.0 1.6e-20 73.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EPS31343.1 - 5.6e-14 52.0 0.0 4.7e-06 26.1 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EPS31343.1 - 0.00077 18.9 0.0 0.24 10.7 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 EPS31343.1 - 0.0018 18.2 0.1 0.004 17.1 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family CVNH PF08881.10 EPS31348.1 - 0.062 14.0 0.5 1.4 9.7 0.1 2.7 2 1 0 2 2 2 0 CVNH domain MFS_1 PF07690.16 EPS31350.1 - 1.4e-18 67.0 31.0 6.6e-16 58.2 24.3 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_43 PF04616.14 EPS31351.1 - 9.2e-25 87.5 5.2 5e-16 58.8 1.6 2.4 2 1 0 2 2 2 2 Glycosyl hydrolases family 43 Peptidase_S9 PF00326.21 EPS31353.1 - 8.2e-52 175.7 0.1 1.9e-51 174.6 0.1 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.12 EPS31353.1 - 0.00035 19.4 0.1 0.0045 15.7 0.1 2.1 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Esterase PF00756.20 EPS31353.1 - 0.013 15.1 0.2 0.029 14.0 0.2 1.6 1 1 0 1 1 1 0 Putative esterase Sec63 PF02889.16 EPS31354.1 - 4e-165 547.2 0.1 1.3e-92 309.6 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EPS31354.1 - 1.1e-48 165.3 3.6 2.6e-26 92.5 0.0 4.1 5 0 0 5 5 5 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 EPS31354.1 - 1.3e-31 109.1 0.1 4.4e-31 107.3 0.1 2.0 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 EPS31354.1 - 1.4e-24 87.0 0.0 1.6e-12 47.8 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EPS31354.1 - 7.4e-11 42.4 0.0 4e-07 30.4 0.0 3.8 2 1 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 EPS31354.1 - 6.4e-06 26.5 2.7 0.021 15.1 0.1 3.6 3 2 0 3 3 3 2 AAA domain AAA_30 PF13604.6 EPS31354.1 - 4.8e-05 23.2 0.0 0.0062 16.3 0.1 2.8 3 0 0 3 3 3 1 AAA domain T2SSE PF00437.20 EPS31354.1 - 0.0011 18.1 0.0 1.3 8.0 0.0 2.7 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_19 PF13245.6 EPS31354.1 - 0.0028 18.0 0.3 2 8.8 0.0 3.1 2 1 0 2 2 2 1 AAA domain PhoH PF02562.16 EPS31354.1 - 0.014 14.9 0.0 1.1 8.7 0.0 2.9 2 0 0 2 2 2 0 PhoH-like protein UvrD-helicase PF00580.21 EPS31354.1 - 0.11 12.0 0.0 1.4 8.4 0.0 2.4 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain MutS_V PF00488.21 EPS31355.1 - 2.8e-72 242.7 0.0 6.3e-72 241.6 0.0 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EPS31355.1 - 2.5e-43 148.5 4.4 5.6e-43 147.4 4.4 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 EPS31355.1 - 7.6e-19 68.0 0.0 2.3e-18 66.5 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EPS31355.1 - 4.4e-06 27.0 0.0 1.2e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 MutS domain II AAA_14 PF13173.6 EPS31355.1 - 0.057 13.5 0.0 1.3 9.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EPS31355.1 - 0.06 13.1 0.0 0.18 11.5 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EPS31355.1 - 0.19 12.2 0.0 0.56 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain US10 PF17617.2 EPS31356.1 - 0.048 13.7 0.2 0.11 12.5 0.0 1.6 2 0 0 2 2 2 0 Viral unique short region 10 RNase_P_p30 PF01876.16 EPS31357.1 - 2.2e-65 220.1 0.0 3.4e-65 219.5 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit p30 Pkinase PF00069.25 EPS31358.1 - 6.9e-65 219.0 0.1 8e-65 218.8 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS31358.1 - 2.6e-18 66.3 0.0 3.5e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EPS31358.1 - 3e-07 30.6 0.5 0.0001 22.3 0.1 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EPS31358.1 - 0.0031 16.4 0.0 0.0058 15.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EPS31358.1 - 0.0082 15.5 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EPS31358.1 - 0.011 15.1 0.1 0.023 14.0 0.1 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EPS31358.1 - 0.024 14.2 0.9 0.046 13.3 0.1 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase tRNA-synt_1 PF00133.22 EPS31359.1 - 4.7e-223 741.8 0.0 7.3e-222 737.9 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EPS31359.1 - 6.9e-31 107.3 1.6 6.9e-31 107.3 1.6 2.5 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EPS31359.1 - 1.8e-14 53.3 0.0 5.5e-07 28.7 0.0 4.3 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 EPS31359.1 - 1.4e-07 31.2 3.5 6.6e-05 22.5 0.0 3.0 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 EPS31359.1 - 0.035 13.5 0.0 0.34 10.2 0.0 2.4 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain DASH_Dad4 PF08650.10 EPS31359.1 - 0.1 12.5 0.9 9.2 6.3 0.2 2.8 3 0 0 3 3 3 0 DASH complex subunit Dad4 PepSY PF03413.19 EPS31359.1 - 0.25 11.9 0.0 0.25 11.9 0.0 3.0 2 1 0 2 2 2 0 Peptidase propeptide and YPEB domain Brix PF04427.18 EPS31360.1 - 1.7e-34 119.6 0.0 2.4e-34 119.2 0.0 1.2 1 0 0 1 1 1 1 Brix domain Tim17 PF02466.19 EPS31361.1 - 3.5e-14 53.1 1.1 5.3e-14 52.5 1.1 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF3716 PF12511.8 EPS31362.1 - 3.1e-12 46.4 8.8 5e-12 45.7 8.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) DUF3431 PF11913.8 EPS31364.1 - 1.1e-87 293.4 0.0 1.4e-87 293.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Mito_carr PF00153.27 EPS31365.1 - 2.3e-66 219.8 1.9 1.1e-21 76.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-rbx1 PF12678.7 EPS31366.1 - 7.9e-11 42.1 1.3 2.3e-10 40.6 1.3 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EPS31366.1 - 3.5e-08 33.6 2.5 3.5e-08 33.6 2.5 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EPS31366.1 - 4.1e-07 29.8 0.5 9.4e-07 28.6 0.5 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EPS31366.1 - 7.3e-06 25.7 3.0 1.7e-05 24.5 3.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPS31366.1 - 1.9e-05 24.6 0.5 4.3e-05 23.5 0.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EPS31366.1 - 2.9e-05 23.8 5.2 8.7e-05 22.3 1.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EPS31366.1 - 9.7e-05 21.9 1.1 0.00023 20.7 1.1 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 EPS31366.1 - 0.00017 21.5 1.7 0.0009 19.2 0.3 2.2 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EPS31366.1 - 0.0024 17.7 1.2 0.0059 16.5 1.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EPS31366.1 - 0.0075 16.3 4.2 0.11 12.5 4.2 2.4 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 EPS31366.1 - 0.058 13.6 0.8 0.13 12.4 0.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 EPS31366.1 - 0.32 11.4 2.2 0.67 10.3 2.2 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_11 PF17123.5 EPS31366.1 - 5.9 6.7 5.8 0.39 10.5 0.2 1.9 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_4 PF14570.6 EPS31366.1 - 6 6.8 5.5 1.1 9.2 1.7 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Ceramidase PF05875.12 EPS31367.1 - 4.4e-82 275.4 3.8 5.3e-82 275.2 3.8 1.0 1 0 0 1 1 1 1 Ceramidase Leader_Trp PF08255.11 EPS31367.1 - 0.24 11.5 2.4 0.73 9.9 2.4 1.8 1 0 0 1 1 1 0 Trp-operon Leader Peptide E1-E2_ATPase PF00122.20 EPS31367.1 - 9.1 5.8 8.1 1.7 8.1 1.8 2.5 3 0 0 3 3 3 0 E1-E2 ATPase TolA_bind_tri PF16331.5 EPS31368.1 - 0.0055 16.8 0.5 0.011 15.7 0.5 1.5 1 0 0 1 1 1 1 TolA binding protein trimerisation DUF16 PF01519.16 EPS31368.1 - 0.0088 16.5 0.4 0.018 15.5 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF16 Fib_alpha PF08702.10 EPS31368.1 - 0.013 15.7 1.4 0.025 14.8 1.4 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family 2-ph_phosp PF04029.14 EPS31368.1 - 0.019 14.1 0.0 0.03 13.5 0.0 1.3 1 0 0 1 1 1 0 2-phosphosulpholactate phosphatase BST2 PF16716.5 EPS31368.1 - 0.1 13.2 0.2 0.2 12.2 0.2 1.4 1 0 0 1 1 1 0 Bone marrow stromal antigen 2 UPF0242 PF06785.11 EPS31368.1 - 0.11 12.6 0.5 0.17 12.0 0.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus MFS_1 PF07690.16 EPS31369.1 - 2.1e-24 86.1 25.1 6.9e-12 45.0 0.9 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.7 EPS31369.1 - 1.9e-06 27.0 6.2 0.016 14.1 0.1 3.8 3 1 1 4 4 4 3 MFS_1 like family MFS_2 PF13347.6 EPS31369.1 - 3.9e-06 25.7 17.0 4.4e-06 25.5 3.2 3.1 4 0 0 4 4 4 2 MFS/sugar transport protein Wzy_C PF04932.15 EPS31369.1 - 3.8 7.1 8.2 14 5.3 2.2 3.6 3 1 0 3 3 3 0 O-Antigen ligase p450 PF00067.22 EPS31372.1 - 5.9e-66 223.1 0.0 7.4e-66 222.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.6 EPS31373.1 - 2.3e-22 79.6 0.0 4.4e-22 78.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPS31373.1 - 6.9e-12 45.9 0.0 2.9e-11 43.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS31373.1 - 7e-09 36.2 0.0 4e-08 33.8 0.0 2.3 4 0 0 4 4 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPS31373.1 - 1.4e-08 35.4 0.0 1.1e-07 32.5 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPS31373.1 - 1e-07 31.9 0.0 2.1e-06 27.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EPS31373.1 - 0.0019 18.0 0.0 0.0041 16.9 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_4 PF02390.17 EPS31373.1 - 0.002 17.6 0.0 0.025 14.1 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.14 EPS31373.1 - 0.0029 17.2 0.0 0.036 13.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_2 PF00891.18 EPS31373.1 - 0.0061 15.9 0.0 0.015 14.6 0.0 1.6 2 0 0 2 2 2 1 O-methyltransferase domain PrmA PF06325.13 EPS31373.1 - 0.013 15.0 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.19 EPS31373.1 - 0.025 14.7 0.0 0.046 13.8 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase GidB PF02527.15 EPS31373.1 - 0.05 12.9 0.0 0.6 9.4 0.0 2.1 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G UPF0146 PF03686.13 EPS31373.1 - 0.064 13.1 0.0 3.1 7.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0146) Ubie_methyltran PF01209.18 EPS31373.1 - 0.15 11.3 0.0 1.1 8.6 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EPS31373.1 - 0.17 11.1 0.0 0.33 10.2 0.0 1.5 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ras PF00071.22 EPS31374.1 - 1.6e-05 24.6 0.0 2.2e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Glyco_hydro_71 PF03659.14 EPS31375.1 - 1.4e-132 442.1 3.2 1.4e-132 442.1 3.2 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 71 Peptidase_S8 PF00082.22 EPS31375.1 - 4.3e-06 26.2 0.0 8.2e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Subtilase family PilS PF08805.11 EPS31375.1 - 0.21 11.4 5.1 0.28 11.0 0.8 3.0 3 0 0 3 3 3 0 PilS N terminal RPN7 PF10602.9 EPS31376.1 - 1.1e-51 175.0 0.7 1.8e-51 174.3 0.1 1.7 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 EPS31376.1 - 5e-10 39.8 0.3 3.1e-09 37.3 0.1 2.3 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 EPS31376.1 - 0.0019 18.2 3.6 1.3 9.3 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EPS31376.1 - 0.089 13.7 1.0 28 5.9 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EPS31376.1 - 0.17 11.7 1.4 18 5.4 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat MHC_I_C PF06623.11 EPS31376.1 - 0.23 11.4 1.2 0.71 9.8 1.2 1.8 1 1 0 1 1 1 0 MHC_I C-terminus TPR_16 PF13432.6 EPS31376.1 - 2.2 9.0 6.0 6.2 7.6 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat adh_short PF00106.25 EPS31377.1 - 7.6e-25 87.5 0.1 8.1e-17 61.3 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EPS31377.1 - 2.1e-20 73.3 0.1 1.9e-18 66.9 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPS31377.1 - 0.0007 19.6 0.0 0.0011 18.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Peptidase_S26 PF10502.9 EPS31377.1 - 0.0034 17.2 0.1 0.01 15.6 0.0 1.8 2 0 0 2 2 2 1 Signal peptidase, peptidase S26 Ntox5 PF15543.6 EPS31378.1 - 0.049 13.5 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial toxin 5 PX PF00787.24 EPS31381.1 - 5.4e-18 65.0 0.0 1.2e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 PX domain DUF2156 PF09924.9 EPS31382.1 - 2.1e-29 102.5 0.0 3e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2156) Phosphoesterase PF04185.14 EPS31385.1 - 1e-62 212.4 0.1 1.4e-62 212.0 0.1 1.2 1 0 0 1 1 1 1 Phosphoesterase family Zn_clus PF00172.18 EPS31387.1 - 6e-08 32.7 8.5 1.1e-07 31.9 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EPS31387.1 - 8.5e-07 28.1 0.1 1.4e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sulfatase PF00884.23 EPS31390.1 - 5.7e-15 55.5 1.6 1.2e-14 54.5 1.6 1.5 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EPS31390.1 - 6.9e-05 22.6 0.2 0.00013 21.7 0.2 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase MFS_1 PF07690.16 EPS31391.1 - 1.9e-54 184.9 50.9 8.9e-40 136.7 24.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EPS31391.1 - 4.2e-07 28.6 0.2 0.00026 19.4 0.5 2.9 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 EPS31391.1 - 6.8e-06 25.2 16.9 0.0011 18.0 3.3 3.1 1 1 2 3 3 3 3 MFS_1 like family DUF1688 PF07958.11 EPS31392.1 - 2.3e-165 550.4 0.0 2.5e-165 550.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Q_salvage PF10343.9 EPS31392.1 - 0.0019 17.9 0.0 0.38 10.3 0.0 2.1 2 0 0 2 2 2 2 Potential Queuosine, Q, salvage protein family Aldedh PF00171.22 EPS31393.1 - 2.8e-141 471.2 0.1 3.4e-141 470.9 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EPS31393.1 - 2.3e-05 23.7 0.0 3.7e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 EPS31393.1 - 0.0016 17.9 0.1 0.34 10.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) FeS_assembly_P PF01883.19 EPS31393.1 - 0.023 14.8 0.1 0.082 13.1 0.1 1.9 2 0 0 2 2 2 0 Iron-sulfur cluster assembly protein AAA_12 PF13087.6 EPS31394.1 - 2.3e-35 122.0 0.0 4.8e-35 121.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EPS31394.1 - 5.6e-19 68.9 0.0 2.5e-18 66.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EPS31394.1 - 5e-08 33.4 0.1 1.6e-05 25.3 0.0 3.2 3 1 0 3 3 3 1 AAA domain DUF2075 PF09848.9 EPS31394.1 - 9.8e-07 28.3 0.3 0.0049 16.2 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) zf-CCCH_4 PF18044.1 EPS31394.1 - 1.8e-06 27.6 6.4 6.3e-06 25.9 6.4 2.0 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 EPS31394.1 - 6.4e-06 26.0 4.6 2.1e-05 24.3 4.6 2.0 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EPS31394.1 - 4.2e-05 23.5 9.0 4.2e-05 23.5 9.0 2.4 2 0 0 2 2 2 1 Zinc finger domain Torus PF16131.5 EPS31394.1 - 0.0003 21.5 0.6 0.0003 21.5 0.6 2.2 2 0 0 2 2 2 1 Torus domain AAA_30 PF13604.6 EPS31394.1 - 0.02 14.6 0.3 0.57 9.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF2373 PF10180.9 EPS31395.1 - 0.021 14.7 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) DUF3659 PF12396.8 EPS31396.1 - 2.2e-168 546.3 91.4 6.1e-21 74.1 1.2 9.5 9 0 0 9 9 9 9 Protein of unknown function (DUF3659) RPW8 PF05659.11 EPS31396.1 - 0.088 12.5 1.9 0.098 12.3 0.6 1.7 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Syntaxin_2 PF14523.6 EPS31396.1 - 0.49 10.8 7.4 7.9 6.9 0.6 3.1 3 0 0 3 3 3 0 Syntaxin-like protein 2C_adapt PF08793.10 EPS31396.1 - 0.6 10.3 2.2 1.2 9.4 0.0 2.6 4 0 0 4 4 4 0 2-cysteine adaptor domain DUF948 PF06103.11 EPS31396.1 - 7.6 6.9 19.0 9.8 6.5 0.1 5.5 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF948) Acetyltransf_1 PF00583.25 EPS31397.1 - 0.0003 21.0 0.0 0.00055 20.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EPS31397.1 - 0.0088 16.5 0.0 0.017 15.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EPS31397.1 - 0.013 15.5 0.0 0.046 13.7 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Mito_carr PF00153.27 EPS31398.1 - 3.6e-64 212.7 2.8 2.4e-20 72.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 EPS31398.1 - 0.11 12.8 0.0 9.5 6.5 0.0 2.5 2 0 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Serine_protease PF18405.1 EPS31398.1 - 0.31 10.2 1.1 1.7 7.7 0.2 2.6 2 1 1 3 3 3 0 Gammaproteobacterial serine protease TauD PF02668.16 EPS31399.1 - 1.7e-49 169.1 0.1 3e-49 168.2 0.1 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.12 EPS31399.1 - 8.2e-06 26.4 0.1 2.1e-05 25.1 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF971) CsiD PF08943.10 EPS31399.1 - 0.00018 20.8 0.1 0.0016 17.6 0.0 2.1 2 0 0 2 2 2 1 CsiD FeoB_Cyto PF17910.1 EPS31399.1 - 0.15 12.6 0.0 0.29 11.7 0.0 1.4 1 0 0 1 1 1 0 FeoB cytosolic helical domain Glutaredoxin PF00462.24 EPS31400.1 - 3.3e-20 72.1 0.0 2.2e-17 63.0 0.0 2.6 2 0 0 2 2 2 2 Glutaredoxin Thioredoxin PF00085.20 EPS31400.1 - 6.6e-12 45.3 0.0 1.6e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EPS31400.1 - 0.0019 18.5 0.0 0.013 15.8 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like YAcAr PF10686.9 EPS31400.1 - 0.079 12.9 0.0 0.35 10.9 0.0 2.0 2 0 0 2 2 2 0 YspA, cpYpsA-related SLOG family RNase_T PF00929.24 EPS31401.1 - 1.3e-08 35.5 0.0 8.1e-08 33.0 0.0 2.0 1 1 0 1 1 1 1 Exonuclease DUF1825 PF08855.10 EPS31401.1 - 0.2 11.6 0.0 0.41 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1825) MFS_1 PF07690.16 EPS31402.1 - 3.3e-20 72.3 85.0 4.5e-15 55.4 51.6 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EPS31402.1 - 6.4e-05 22.4 20.1 0.0001 21.8 20.1 1.4 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB MWFE PF15879.5 EPS31402.1 - 0.015 15.4 1.6 0.14 12.3 0.2 2.8 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase MWFE subunit zf-C2H2_3rep PF18868.1 EPS31403.1 - 4.6 7.9 5.9 0.45 11.2 0.3 2.2 3 0 0 3 3 3 0 Zinc finger C2H2-type, 3 repeats Beta_elim_lyase PF01212.21 EPS31404.1 - 6.3e-70 235.7 0.0 7.4e-70 235.5 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EPS31404.1 - 0.00023 19.8 0.0 0.00039 19.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.20 EPS31404.1 - 0.092 11.5 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Pkinase PF00069.25 EPS31405.1 - 4.3e-69 232.8 0.0 8.3e-69 231.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS31405.1 - 1.5e-32 112.9 0.0 2.4e-32 112.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EPS31405.1 - 4.1e-10 39.9 0.2 2.3e-09 37.5 0.2 2.3 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.6 EPS31405.1 - 1.9e-05 24.2 0.0 3.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EPS31405.1 - 0.00024 21.1 0.2 0.13 12.2 0.3 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Yop-YscD_cpl PF16697.5 EPS31405.1 - 0.00041 20.6 0.0 0.00096 19.4 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 EPS31405.1 - 0.003 17.0 0.1 0.0055 16.1 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EPS31405.1 - 0.053 13.2 0.1 0.096 12.3 0.1 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EPS31405.1 - 0.13 11.0 0.0 0.32 9.7 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase CaMBD PF02888.16 EPS31405.1 - 0.15 12.3 0.2 0.37 11.0 0.2 1.6 1 0 0 1 1 1 0 Calmodulin binding domain Glyco_transf_34 PF05637.12 EPS31406.1 - 2.6e-64 217.2 0.4 3.3e-64 216.9 0.4 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family NDUFB10 PF10249.9 EPS31407.1 - 0.016 15.7 0.0 0.018 15.6 0.0 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 BRO1 PF03097.18 EPS31408.1 - 9.4e-07 28.0 0.0 2.2e-06 26.8 0.0 1.7 1 1 0 1 1 1 1 BRO1-like domain SDH_alpha PF03313.15 EPS31408.1 - 0.07 12.8 0.1 0.26 10.9 0.1 1.8 2 0 0 2 2 2 0 Serine dehydratase alpha chain MFS_1 PF07690.16 EPS31409.1 - 2.4e-37 128.7 23.3 3.2e-37 128.3 23.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS31409.1 - 1.6e-07 30.6 4.9 1.6e-07 30.6 4.9 2.8 2 1 1 3 3 3 2 Sugar (and other) transporter AtpR PF12966.7 EPS31409.1 - 0.13 12.7 2.7 0.13 12.7 0.4 2.3 2 0 0 2 2 2 0 N-ATPase, AtpR subunit Bromo_TP PF07524.13 EPS31410.1 - 9e-07 28.8 0.0 1.3e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 EPS31410.1 - 0.046 13.8 0.0 0.072 13.2 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CEBP1_N PF16368.5 EPS31410.1 - 0.084 12.4 0.4 1.9 7.9 0.3 2.1 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein 1 N-terminus TAFII55_N PF04658.13 EPS31411.1 - 8e-53 178.4 0.2 2e-52 177.2 0.0 1.7 2 0 0 2 2 2 1 TAFII55 protein conserved region FAM76 PF16046.5 EPS31411.1 - 6.4 6.0 5.9 2.7 7.3 3.3 1.6 2 0 0 2 2 2 0 FAM76 protein Vir_act_alpha_C PF10400.9 EPS31412.1 - 8.9 7.1 8.9 0.43 11.3 0.4 2.5 2 1 0 2 2 2 0 Virulence activator alpha C-term Abhydrolase_1 PF00561.20 EPS31413.1 - 1.6e-16 60.7 0.1 3.8e-16 59.5 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPS31413.1 - 1.9e-15 58.1 1.0 3e-15 57.4 1.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.11 EPS31413.1 - 7.2e-06 25.2 0.0 1e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Hydrolase_4 PF12146.8 EPS31413.1 - 0.0012 18.2 0.1 0.0018 17.6 0.1 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 EPS31413.1 - 0.0071 15.3 0.1 0.011 14.7 0.1 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme AXE1 PF05448.12 EPS31413.1 - 0.073 11.7 0.0 0.22 10.2 0.0 1.7 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) EHN PF06441.12 EPS31413.1 - 0.11 12.8 0.3 0.22 11.9 0.3 1.5 1 0 0 1 1 1 0 Epoxide hydrolase N terminus ECH_1 PF00378.20 EPS31414.1 - 2.8e-22 79.3 0.0 3.2e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EPS31414.1 - 0.0035 16.9 0.0 0.004 16.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Ofd1_CTDD PF10637.9 EPS31417.1 - 1.5e-99 332.5 0.2 1.8e-95 319.2 0.2 2.1 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 EPS31417.1 - 1.6e-26 92.8 0.0 3.6e-26 91.7 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 EPS31417.1 - 7.9e-14 52.3 0.0 1.8e-13 51.2 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Tub_N PF16322.5 EPS31417.1 - 0.13 12.6 10.1 0.44 10.9 10.1 1.8 1 0 0 1 1 1 0 Tubby N-terminal DUF4746 PF15928.5 EPS31417.1 - 0.24 10.8 10.1 0.57 9.6 10.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Nop14 PF04147.12 EPS31417.1 - 2.9 6.0 11.1 4.8 5.3 11.1 1.3 1 0 0 1 1 1 0 Nop14-like family HLH PF00010.26 EPS31420.1 - 1.8e-15 56.6 1.1 4.2e-15 55.4 1.1 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Fzo_mitofusin PF04799.13 EPS31420.1 - 0.047 13.2 2.5 0.068 12.7 2.5 1.2 1 0 0 1 1 1 0 fzo-like conserved region CCDC32 PF14989.6 EPS31420.1 - 0.072 13.1 0.6 0.14 12.2 0.6 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing 32 SLX9 PF15341.6 EPS31420.1 - 0.5 10.8 4.2 1.4 9.3 4.2 1.7 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 Glyco_transf_4 PF13439.6 EPS31421.1 - 0.23 11.5 1.7 0.4 10.7 0.1 1.9 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Phosphodiest PF01663.22 EPS31424.1 - 1.7e-88 297.6 0.1 2.4e-88 297.1 0.1 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EPS31424.1 - 1.6e-05 24.4 0.0 0.045 13.1 0.0 2.3 1 1 1 2 2 2 2 Sulfatase RRN3 PF05327.11 EPS31424.1 - 0.35 9.4 11.1 0.81 8.2 11.1 1.5 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Med13_C PF06333.12 EPS31424.1 - 1.9 7.7 4.7 3.4 6.8 4.7 1.3 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain BCS1_N PF08740.11 EPS31425.1 - 1e-45 156.0 5.5 1.6e-45 155.4 5.5 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EPS31425.1 - 3.8e-17 63.0 0.0 5e-07 30.2 0.0 2.6 1 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EPS31425.1 - 0.0035 17.7 0.0 0.0086 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EPS31425.1 - 0.005 17.4 0.0 0.015 15.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 EPS31425.1 - 0.006 15.8 0.0 0.013 14.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 EPS31425.1 - 0.0087 15.8 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 EPS31425.1 - 0.038 13.3 0.0 0.073 12.4 0.0 1.4 1 0 0 1 1 1 0 KaiC Cytidylate_kin PF02224.18 EPS31425.1 - 0.043 13.6 0.5 0.21 11.3 0.1 2.3 3 0 0 3 3 3 0 Cytidylate kinase TIP49 PF06068.13 EPS31425.1 - 0.059 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_29 PF13555.6 EPS31425.1 - 0.1 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 EPS31425.1 - 0.11 12.5 0.0 0.37 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Kinesin PF00225.23 EPS31426.1 - 1e-111 373.1 0.0 1.6e-111 372.5 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.8 EPS31426.1 - 7.5e-45 153.3 0.0 2.2e-44 151.8 0.0 1.9 1 0 0 1 1 1 1 Kinesin protein Kinesin_assoc PF16183.5 EPS31426.1 - 2.2e-38 132.2 9.4 2.1e-31 109.4 0.6 3.2 2 1 1 3 3 3 2 Kinesin-associated Microtub_bd PF16796.5 EPS31426.1 - 8.7e-24 84.2 0.0 2.3e-23 82.8 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding KIF1B PF12423.8 EPS31426.1 - 2e-08 34.5 0.2 9e-08 32.4 0.2 2.2 1 0 0 1 1 1 1 Kinesin protein 1B PH PF00169.29 EPS31426.1 - 3.7e-06 27.4 0.0 1.4e-05 25.5 0.0 2.0 2 0 0 2 2 2 1 PH domain FHA PF00498.26 EPS31426.1 - 2.1e-05 24.7 0.1 0.00018 21.8 0.1 2.7 3 0 0 3 3 3 1 FHA domain UPF0242 PF06785.11 EPS31426.1 - 0.28 11.3 10.2 0.11 12.6 0.6 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Adaptin_binding PF10199.9 EPS31426.1 - 2.3 8.8 9.1 20 5.8 0.2 3.0 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Spore_III_AB PF09548.10 EPS31426.1 - 8.8 6.4 6.9 24 5.0 0.6 2.8 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) CBFB_NFYA PF02045.15 EPS31428.1 - 1.8e-28 98.9 4.6 3.1e-28 98.2 4.6 1.4 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Hus1 PF04005.12 EPS31428.1 - 0.018 14.2 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 Hus1-like protein TFIIA PF03153.13 EPS31428.1 - 0.021 14.8 15.9 0.024 14.7 15.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3546 PF12066.8 EPS31430.1 - 6e-31 106.9 1.3 6e-31 106.9 1.3 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3546) DUF4187 PF13821.6 EPS31430.1 - 9.3e-13 47.8 0.5 1.9e-12 46.8 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.13 EPS31430.1 - 2.3e-11 44.4 0.2 2.3e-11 44.4 0.2 2.7 2 1 1 3 3 3 1 Arsenite-resistance protein 2 bZIP_1 PF00170.21 EPS31432.1 - 8.2e-05 22.6 10.0 0.00017 21.6 10.0 1.4 1 0 0 1 1 1 1 bZIP transcription factor TEX13 PF15186.6 EPS31432.1 - 0.0055 16.4 7.5 0.0089 15.7 7.5 1.2 1 0 0 1 1 1 1 Testis-expressed sequence 13 protein family bZIP_2 PF07716.15 EPS31432.1 - 0.016 15.3 5.6 0.016 15.3 5.6 2.2 2 0 0 2 2 2 0 Basic region leucine zipper DUF5082 PF16888.5 EPS31432.1 - 0.072 13.4 4.8 0.11 12.7 4.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) zf-C2H2_aberr PF17017.5 EPS31432.1 - 0.14 12.3 0.3 0.25 11.5 0.3 1.3 1 0 0 1 1 1 0 Aberrant zinc-finger YscJ_FliF PF01514.17 EPS31432.1 - 0.27 10.9 1.9 2.4 7.8 1.9 2.1 2 0 0 2 2 2 0 Secretory protein of YscJ/FliF family bZIP_Maf PF03131.17 EPS31432.1 - 4.7 7.8 12.0 8.5 7.0 12.0 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor eIF-3_zeta PF05091.12 EPS31433.1 - 1.8e-205 683.8 0.0 2.3e-205 683.5 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Keratin_2_head PF16208.5 EPS31433.1 - 0.019 15.1 12.8 0.035 14.2 12.8 1.3 1 0 0 1 1 1 0 Keratin type II head Cupin_1 PF00190.22 EPS31434.1 - 6.8e-39 132.9 0.1 2.2e-19 69.6 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 EPS31434.1 - 8.7e-24 83.0 0.2 1.1e-12 47.5 0.1 2.5 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 EPS31434.1 - 1.8e-08 34.4 0.1 2.5e-05 24.2 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_3 PF05899.12 EPS31434.1 - 1.9e-08 33.9 0.0 0.0059 16.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_6 PF12852.7 EPS31434.1 - 0.00028 20.7 0.0 0.17 11.6 0.0 2.3 2 0 0 2 2 2 2 Cupin Cupin_4 PF08007.12 EPS31434.1 - 0.00041 19.9 0.0 0.021 14.3 0.0 2.2 2 0 0 2 2 2 1 Cupin superfamily protein MannoseP_isomer PF01050.18 EPS31434.1 - 0.00074 19.4 0.0 0.024 14.5 0.0 2.2 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase 3-HAO PF06052.12 EPS31434.1 - 0.063 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase DUF1971 PF09313.11 EPS31434.1 - 0.086 12.9 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1971) Abhydro_lipase PF04083.16 EPS31439.1 - 1.1e-20 73.0 0.0 4.8e-20 70.9 0.0 2.1 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 EPS31439.1 - 2e-06 27.7 0.8 5.2e-05 23.0 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EPS31439.1 - 0.0067 15.7 0.0 0.024 13.9 0.0 1.9 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Aa_trans PF01490.18 EPS31441.1 - 5.4e-54 183.5 39.2 6.1e-54 183.3 39.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Sugar_tr PF00083.24 EPS31442.1 - 2.2e-129 432.3 25.4 2.5e-129 432.1 25.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS31442.1 - 1.5e-21 76.7 36.8 1.2e-14 54.0 13.6 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EPS31442.1 - 1.4e-06 27.4 0.0 1.1e-05 24.5 0.0 2.6 1 1 0 1 1 1 1 MFS_1 like family Ilm1 PF10311.9 EPS31442.1 - 0.24 11.0 2.2 0.18 11.5 0.6 1.6 2 0 0 2 2 2 0 Increased loss of mitochondrial DNA protein 1 Metallophos PF00149.28 EPS31443.1 - 1.5e-08 35.4 0.0 5.2e-08 33.6 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Cation_efflux PF01545.21 EPS31444.1 - 1.2e-52 178.5 0.3 2.2e-52 177.7 0.3 1.4 1 1 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EPS31444.1 - 0.039 14.1 0.3 0.039 14.1 0.3 2.3 2 0 0 2 2 2 0 Dimerisation domain of Zinc Transporter Glyco_hydro_3 PF00933.21 EPS31445.1 - 1.4e-58 198.8 0.0 1.7e-58 198.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Abhydrolase_1 PF00561.20 EPS31446.1 - 1e-25 90.8 0.0 2e-24 86.7 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPS31446.1 - 7.1e-16 59.5 0.0 1.1e-15 58.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPS31446.1 - 1.3e-11 44.2 0.1 2e-11 43.6 0.1 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EPS31446.1 - 7.7e-07 29.4 0.0 9.9e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 EPS31446.1 - 4.5e-06 26.5 0.1 6.8e-06 25.9 0.1 1.3 1 1 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 EPS31446.1 - 5.6e-06 26.2 0.3 0.0021 17.8 0.3 2.2 1 1 0 1 1 1 1 PGAP1-like protein Ser_hydrolase PF06821.13 EPS31446.1 - 0.0029 17.5 0.0 0.004 17.0 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase UPF0227 PF05728.12 EPS31446.1 - 0.016 15.2 0.1 0.027 14.4 0.1 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) Palm_thioest PF02089.15 EPS31446.1 - 0.047 13.5 0.0 0.056 13.3 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF915 PF06028.11 EPS31446.1 - 0.049 13.0 0.0 4.2 6.6 0.0 2.1 1 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF2048 PF09752.9 EPS31446.1 - 0.055 12.6 0.0 0.58 9.2 0.0 2.0 2 0 0 2 2 2 0 Abhydrolase domain containing 18 Nipped-B_C PF12830.7 EPS31446.1 - 0.16 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus MFS_1 PF07690.16 EPS31447.1 - 2.5e-38 131.9 58.2 2.7e-36 125.2 54.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EPS31447.1 - 4.7e-08 31.9 20.3 4.7e-08 31.9 20.3 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SLATT_5 PF18160.1 EPS31447.1 - 1.1 8.6 2.8 0.65 9.3 0.5 1.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 Sugar_tr PF00083.24 EPS31447.1 - 1.1 8.0 49.4 0.012 14.5 19.2 3.1 1 1 3 4 4 4 0 Sugar (and other) transporter Metallophos PF00149.28 EPS31448.1 - 1.3e-13 52.0 0.5 2.1e-13 51.3 0.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase His_Phos_2 PF00328.22 EPS31449.1 - 9.5e-06 25.2 0.0 0.025 13.9 0.0 2.1 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Glyco_transf_28 PF03033.20 EPS31451.1 - 1.1e-18 67.7 0.3 7.3e-14 52.0 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 EPS31451.1 - 4.1e-07 29.2 0.0 6.1e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.11 EPS31451.1 - 1.5e-06 28.5 0.0 5e-06 26.8 0.0 1.9 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Glyco_tran_28_C PF04101.16 EPS31451.1 - 0.0014 18.6 0.0 0.0029 17.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain DHHC PF01529.20 EPS31452.1 - 2.7e-31 108.5 6.5 2.7e-31 108.5 6.5 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase DNA_mis_repair PF01119.19 EPS31453.1 - 1.9e-10 40.4 0.0 3.9e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.26 EPS31453.1 - 4.4e-10 40.1 0.1 1.4e-09 38.5 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EPS31453.1 - 5.7e-09 35.9 0.0 1.4e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Kelch_5 PF13854.6 EPS31454.1 - 3.5e-14 52.4 0.7 1.2e-13 50.7 0.6 2.0 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.25 EPS31454.1 - 2.4e-05 23.8 1.1 0.0063 16.1 0.1 3.0 2 1 0 2 2 2 2 Kelch motif Kelch_4 PF13418.6 EPS31454.1 - 0.0022 18.0 1.1 0.02 14.9 0.0 3.0 3 1 0 3 3 3 1 Galactose oxidase, central domain Kelch_6 PF13964.6 EPS31454.1 - 0.015 15.5 2.2 0.18 12.2 0.1 2.9 2 1 0 2 2 2 0 Kelch motif DUF2207 PF09972.9 EPS31454.1 - 0.06 12.1 0.0 0.095 11.5 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Kelch_2 PF07646.15 EPS31454.1 - 0.069 13.2 0.0 2.2 8.4 0.1 2.8 2 1 0 2 2 2 0 Kelch motif DUF4381 PF14316.6 EPS31454.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Peptidase_Mx1 PF15890.5 EPS31455.1 - 0.013 15.0 0.4 0.026 14.0 0.4 1.4 1 0 0 1 1 1 0 Putative zinc-binding metallo-peptidase EthD PF07110.11 EPS31456.1 - 9.5e-16 58.7 0.3 1.5e-15 58.1 0.3 1.3 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 EPS31456.1 - 0.045 14.2 0.1 0.055 13.9 0.1 1.3 1 1 0 1 1 1 0 Methylmuconolactone methyl-isomerase DUF1295 PF06966.12 EPS31457.1 - 5.8e-33 114.4 0.0 8.1e-33 113.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 EPS31457.1 - 9.3e-05 22.4 0.0 0.00078 19.4 0.0 2.2 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 EPS31457.1 - 0.0017 18.7 0.3 0.0036 17.7 0.0 1.7 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EPS31457.1 - 0.0047 17.3 0.0 0.013 15.9 0.0 1.7 1 0 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.17 EPS31457.1 - 0.006 15.4 0.0 0.0091 14.8 0.0 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Epimerase PF01370.21 EPS31459.1 - 1.6e-09 37.6 0.4 0.00065 19.2 0.3 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EPS31459.1 - 1.1e-07 31.9 1.8 2.4e-07 30.8 1.8 1.6 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 EPS31459.1 - 9e-07 29.4 0.1 2.8e-06 27.8 0.1 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 EPS31459.1 - 1.4e-05 24.8 0.4 2.3e-05 24.1 0.4 1.3 1 0 0 1 1 1 1 NmrA-like family DXP_reductoisom PF02670.16 EPS31459.1 - 0.0002 22.1 0.1 0.00037 21.2 0.1 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase 3Beta_HSD PF01073.19 EPS31459.1 - 0.00073 18.6 0.0 0.0039 16.3 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EPS31459.1 - 0.065 12.6 0.1 1 8.6 0.0 2.3 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EPS31459.1 - 0.2 10.7 0.0 0.37 9.9 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein MFS_1 PF07690.16 EPS31460.1 - 8.6e-46 156.5 58.7 4e-44 151.0 60.2 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EPS31460.1 - 3e-25 88.7 27.3 4.5e-25 88.1 27.0 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EPS31460.1 - 1.3e-11 44.1 14.2 1.3e-11 44.1 14.2 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter SLATT_4 PF18186.1 EPS31460.1 - 0.081 12.6 0.5 16 5.1 0.0 2.4 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 OATP PF03137.20 EPS31460.1 - 3.1 6.0 18.0 0.037 12.3 2.9 3.3 3 2 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Pkinase PF00069.25 EPS31461.1 - 3.2e-71 239.8 0.0 5.1e-71 239.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS31461.1 - 1.7e-45 155.3 0.0 2.8e-45 154.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 EPS31461.1 - 6.7e-08 32.6 0.1 0.012 15.7 0.0 2.8 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 EPS31461.1 - 4.4e-06 26.2 0.0 1e-05 25.0 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EPS31461.1 - 0.014 14.4 0.0 0.023 13.6 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain OPA3 PF07047.12 EPS31462.1 - 1.3e-48 163.9 4.3 1.9e-48 163.4 4.3 1.2 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) BatD PF13584.6 EPS31462.1 - 0.0012 17.8 1.5 0.0017 17.3 1.5 1.2 1 0 0 1 1 1 1 Oxygen tolerance DUF4472 PF14739.6 EPS31462.1 - 0.39 11.5 0.1 0.39 11.5 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4472) Myosin_head PF00063.21 EPS31463.1 - 1.6e-242 806.6 1.3 2e-242 806.3 1.3 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 EPS31463.1 - 1.7e-53 181.1 0.0 3e-53 180.3 0.0 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 EPS31463.1 - 6.7e-13 48.0 0.1 1.4e-12 47.0 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EPS31463.1 - 6e-08 32.4 0.0 1.8e-07 30.9 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EPS31463.1 - 1.5e-07 31.0 0.0 4.2e-07 29.5 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain AAA_16 PF13191.6 EPS31463.1 - 0.041 14.3 0.0 0.14 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Hpr_kinase_C PF07475.12 EPS31463.1 - 0.041 13.4 0.8 8.5 5.9 0.1 2.9 3 0 0 3 3 3 0 HPr Serine kinase C-terminal domain IQ PF00612.27 EPS31463.1 - 0.048 13.5 10.0 1.4 8.9 1.2 2.6 2 0 0 2 2 2 0 IQ calmodulin-binding motif AAA_22 PF13401.6 EPS31463.1 - 0.051 13.8 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EPS31463.1 - 0.092 12.7 0.0 0.29 11.0 0.0 1.8 2 0 0 2 2 2 0 NACHT domain DUF3613 PF12266.8 EPS31464.1 - 0.19 11.5 1.6 0.25 11.1 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3613) DUF3759 PF12585.8 EPS31464.1 - 0.46 10.6 8.2 0.03 14.4 2.5 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3759) WD40 PF00400.32 EPS31465.1 - 4.4e-05 24.2 3.1 0.00017 22.3 0.2 3.4 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF2415 PF10313.9 EPS31465.1 - 0.054 13.4 0.0 0.18 11.7 0.0 1.9 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) Chitin_synth_2 PF03142.15 EPS31466.1 - 1.4e-289 961.1 0.1 2.1e-289 960.5 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 EPS31466.1 - 7.9e-12 45.5 5.5 3.3e-11 43.5 5.5 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EPS31466.1 - 5e-09 36.4 0.3 5.3e-08 33.0 0.0 2.7 3 1 0 3 3 3 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EPS31466.1 - 0.0003 20.6 0.1 0.025 14.4 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EPS31466.1 - 0.0021 17.5 0.1 0.0084 15.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 21 Abhydrolase_6 PF12697.7 EPS31467.1 - 1.3e-11 45.6 7.8 1.7e-11 45.1 7.3 1.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EPS31467.1 - 7.8e-11 42.1 0.4 1.1e-10 41.7 0.4 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EPS31467.1 - 3.3e-05 23.3 0.0 5.2e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 EPS31467.1 - 0.00051 20.2 0.1 0.0007 19.8 0.1 1.2 1 0 0 1 1 1 1 Thioesterase domain ADH_N PF08240.12 EPS31468.1 - 6e-06 26.1 0.0 1.5e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPS31468.1 - 0.042 13.8 0.1 0.094 12.7 0.1 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF1859 PF08948.10 EPS31469.1 - 0.081 12.9 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1859) Sde2_N_Ubi PF13019.6 EPS31470.1 - 2.9 7.7 12.4 0.028 14.2 1.7 2.6 2 1 0 2 2 2 0 Silencing defective 2 N-terminal ubiquitin domain Sel1 PF08238.12 EPS31473.1 - 1.9e-40 136.4 25.5 2.2e-06 28.1 0.1 7.4 7 0 0 7 7 7 7 Sel1 repeat PARP PF00644.20 EPS31474.1 - 1.7e-58 197.5 0.3 1.7e-57 194.2 0.0 2.3 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 EPS31474.1 - 5.1e-43 146.4 0.1 1e-42 145.5 0.1 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 EPS31474.1 - 2.1e-23 82.2 0.1 2.1e-23 82.2 0.1 2.2 2 0 0 2 2 2 1 WGR domain BRCT PF00533.26 EPS31474.1 - 4.6e-09 36.5 0.0 1.2e-08 35.3 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EPS31474.1 - 1.2e-06 28.3 0.1 2.4e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 EPS31474.1 - 0.00096 19.5 0.0 0.0028 18.0 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Ndc1_Nup PF09531.10 EPS31474.1 - 0.34 9.5 3.4 0.49 9.0 3.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup LicD PF04991.13 EPS31474.1 - 0.38 10.9 5.0 0.36 10.9 3.0 2.0 2 0 0 2 2 2 0 LicD family Toprim_2 PF13155.6 EPS31474.1 - 0.62 10.5 2.9 5.2 7.6 1.1 3.0 2 1 0 2 2 2 0 Toprim-like Hid1 PF12722.7 EPS31474.1 - 7.1 4.6 9.0 11 4.0 9.0 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PfkB PF00294.24 EPS31475.1 - 1e-38 133.4 5.9 1.3e-38 133.0 5.9 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Zn_clus PF00172.18 EPS31476.1 - 5.5e-09 36.0 10.6 1e-08 35.1 10.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 EPS31477.1 - 6.8e-21 74.8 0.0 1.3e-20 73.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS31477.1 - 1.8e-08 34.0 0.3 1.5e-07 31.0 0.0 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EPS31477.1 - 0.0041 16.5 0.2 0.18 11.1 0.1 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EPS31477.1 - 0.0056 16.6 0.6 0.019 14.9 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EPS31477.1 - 0.055 12.8 0.0 0.087 12.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sugar_tr PF00083.24 EPS31478.1 - 6.5e-112 374.7 28.0 1.2e-111 373.8 28.0 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS31478.1 - 1.3e-23 83.6 58.7 4.8e-15 55.4 25.2 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 EPS31478.1 - 2.3 6.6 36.5 0.1 11.1 11.3 3.6 2 2 0 2 2 2 0 MFS/sugar transport protein Fungal_trans_2 PF11951.8 EPS31479.1 - 2.4e-09 36.5 0.1 3.4e-09 36.0 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Aa_trans PF01490.18 EPS31480.1 - 9.8e-40 136.5 35.3 1.2e-39 136.2 35.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2649 PF10854.8 EPS31480.1 - 7.6 6.9 11.5 7.4 7.0 0.4 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2649) Phage_holin_1 PF04531.13 EPS31480.1 - 9.3 6.9 9.3 2.4 8.8 3.7 3.0 2 1 0 2 2 2 0 Bacteriophage holin SIN1 PF05422.12 EPS31481.1 - 0.05 14.1 2.9 0.055 14.0 2.9 1.1 1 0 0 1 1 1 0 Stress-activated map kinase interacting protein 1 (SIN1) Ank_2 PF12796.7 EPS31482.1 - 3.9e-45 152.3 0.6 8.7e-16 58.3 0.2 4.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPS31482.1 - 2.9e-36 123.4 4.6 4.2e-10 40.0 0.0 5.8 1 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPS31482.1 - 1.1e-32 108.4 0.3 0.00039 20.7 0.1 7.3 7 0 0 7 7 7 6 Ankyrin repeat Ank PF00023.30 EPS31482.1 - 2.2e-31 106.9 11.0 0.0001 22.6 0.1 7.0 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 EPS31482.1 - 4.1e-18 65.2 9.8 5e-05 23.5 0.2 6.7 2 2 5 7 7 7 5 Ankyrin repeats (many copies) FA PF08736.11 EPS31482.1 - 0.01 15.9 3.5 2.5 8.3 0.1 4.1 4 0 0 4 4 4 0 FERM adjacent (FA) DUF2384 PF09722.10 EPS31482.1 - 1.2 9.3 6.9 23 5.1 0.0 4.2 6 0 0 6 6 6 0 Protein of unknown function (DUF2384) Glyco_hydro_26 PF02156.15 EPS31483.1 - 1.3e-80 271.1 1.5 1.7e-80 270.8 1.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 CBM_1 PF00734.18 EPS31483.1 - 2.4e-11 43.4 12.0 2.4e-11 43.4 12.0 3.2 3 0 0 3 3 3 1 Fungal cellulose binding domain Glyco_hydro_12 PF01670.16 EPS31484.1 - 2.9e-80 269.3 12.9 3.3e-80 269.1 12.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Glyco_hydro_17 PF00332.18 EPS31486.1 - 0.0073 15.9 0.2 0.043 13.4 0.2 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 AcetylCoA_hydro PF02550.15 EPS31489.1 - 1.1e-49 169.2 0.0 1.6e-49 168.6 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 EPS31489.1 - 1.4e-41 141.9 0.0 2.5e-41 141.2 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Sin3a_C PF16879.5 EPS31490.1 - 3.6e-74 250.1 4.5 3.6e-74 250.1 4.5 3.7 4 0 0 4 4 4 2 C-terminal domain of Sin3a protein PAH PF02671.21 EPS31490.1 - 1.8e-42 143.2 5.2 1.3e-17 63.6 0.0 3.9 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.12 EPS31490.1 - 1.9e-39 133.7 0.0 6.7e-39 131.9 0.0 2.0 1 0 0 1 1 1 1 Sin3 family co-repressor WD40 PF00400.32 EPS31491.1 - 4.7e-13 49.4 4.2 0.064 14.2 0.3 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS31491.1 - 0.0067 16.7 0.2 2.8 8.3 0.0 3.9 4 2 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain AhpC-TSA_2 PF13911.6 EPS31494.1 - 1.3e-07 31.7 0.0 1.8e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 EPS31494.1 - 6.1e-07 29.4 0.0 8.1e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EPS31494.1 - 3.2e-05 23.7 0.0 4.4e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin FAD_binding_2 PF00890.24 EPS31495.1 - 4e-84 283.1 1.1 5e-84 282.8 1.1 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.28 EPS31495.1 - 1.4e-21 76.4 0.1 3e-20 72.1 0.0 2.9 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.24 EPS31495.1 - 1.5e-12 47.8 2.4 4.6e-12 46.2 2.4 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EPS31495.1 - 4e-08 33.0 1.9 1.3e-07 31.3 1.9 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPS31495.1 - 1e-07 31.5 1.3 1.4e-06 27.7 0.9 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPS31495.1 - 5e-07 29.9 3.7 1.1e-06 28.8 0.6 2.9 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EPS31495.1 - 4.4e-06 26.2 0.1 0.036 13.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EPS31495.1 - 1.3e-05 24.2 4.3 0.0043 15.8 0.2 3.1 3 0 0 3 3 3 2 HI0933-like protein FAD_binding_3 PF01494.19 EPS31495.1 - 5.3e-05 22.6 0.1 7.8e-05 22.1 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EPS31495.1 - 5.6e-05 22.5 1.2 0.01 15.1 0.3 2.3 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 EPS31495.1 - 0.0013 17.9 2.5 0.16 11.0 0.6 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Amino_oxidase PF01593.24 EPS31495.1 - 0.004 16.5 0.6 3 7.0 0.0 2.9 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.21 EPS31495.1 - 0.064 12.5 0.4 0.14 11.5 0.4 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 EPS31495.1 - 0.07 13.7 1.9 13 6.4 0.3 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Bac_rhamnosid6H PF17389.2 EPS31496.1 - 4.2e-132 440.5 0.1 9.8e-132 439.3 0.0 1.6 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain Bac_rhamnosid_N PF08531.10 EPS31496.1 - 2.8e-57 193.3 0.0 4.9e-57 192.5 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Bac_rhamnosid PF05592.11 EPS31496.1 - 2.7e-23 81.9 0.0 4.8e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase concanavalin-like domain Bac_rhamnosid_C PF17390.2 EPS31496.1 - 4.6e-21 74.4 0.4 1.2e-20 73.1 0.4 1.7 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase C-terminal domain Nucleo_P87 PF07267.11 EPS31496.1 - 0.055 12.3 0.0 0.079 11.8 0.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 MBD PF01429.19 EPS31496.1 - 0.094 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Methyl-CpG binding domain Ion_trans_2 PF07885.16 EPS31497.1 - 1.9e-26 91.8 21.7 1.4e-16 60.2 8.4 3.9 5 0 0 5 5 5 2 Ion channel SLC3A2_N PF16028.5 EPS31497.1 - 0.094 12.3 0.4 0.41 10.2 0.4 2.1 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus Lig_chan PF00060.26 EPS31497.1 - 7.3 6.4 12.6 2.8 7.8 6.2 2.7 2 1 0 2 2 2 0 Ligand-gated ion channel PCI PF01399.27 EPS31498.1 - 1.5e-13 51.2 0.0 3.8e-13 49.8 0.0 1.7 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.9 EPS31498.1 - 3.1e-05 23.8 0.1 6.7e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN7 DUF4012 PF13196.6 EPS31498.1 - 0.092 13.2 0.0 18 5.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4012) TPR_14 PF13428.6 EPS31498.1 - 0.66 11.0 3.9 55 5.0 0.0 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat TFIIF_beta_N PF17683.1 EPS31499.1 - 3.4e-30 105.5 0.6 3.4e-30 105.5 0.6 1.7 2 0 0 2 2 2 1 TFIIF, beta subunit N-terminus TFIIF_beta PF02270.15 EPS31499.1 - 9.2e-30 102.6 0.6 1.6e-29 101.8 0.6 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain Tau95 PF09734.9 EPS31499.1 - 0.037 14.8 5.8 0.19 12.6 5.8 2.1 1 1 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain zf-CCCH PF00642.24 EPS31500.1 - 4.5e-13 48.7 29.1 3.3e-05 23.7 1.2 5.2 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EPS31500.1 - 2.8e-09 36.7 29.0 0.04 14.0 1.5 6.1 5 1 0 5 5 5 4 Zinc finger domain zf-CCCH_3 PF15663.5 EPS31500.1 - 0.0005 20.3 16.3 0.0053 17.0 0.8 3.8 3 1 1 4 4 4 3 Zinc-finger containing family zf-C3H1 PF10650.9 EPS31500.1 - 0.0023 17.6 7.4 0.073 12.8 0.0 4.2 4 0 0 4 4 4 1 Putative zinc-finger domain zf-CCCH_4 PF18044.1 EPS31500.1 - 0.0055 16.5 27.9 0.037 13.8 0.0 5.4 6 1 0 6 6 6 2 CCCH-type zinc finger Torus PF16131.5 EPS31500.1 - 0.0058 17.3 26.2 0.091 13.5 0.4 4.8 2 1 3 5 5 5 3 Torus domain Ribosomal_60s PF00428.19 EPS31500.1 - 0.032 14.8 3.0 0.12 13.0 3.0 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein zf-CCCH_2 PF14608.6 EPS31500.1 - 0.98 10.0 33.5 0.076 13.5 2.2 4.8 5 0 0 5 5 5 0 RNA-binding, Nab2-type zinc finger Cwf_Cwc_15 PF04889.12 EPS31500.1 - 2.7 7.6 11.9 2.3 7.9 6.3 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein bZIP_2 PF07716.15 EPS31503.1 - 4.7e-08 33.0 22.0 1.1e-07 31.8 11.1 2.9 1 1 0 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.21 EPS31503.1 - 5.9e-07 29.5 21.8 2.3e-06 27.6 17.2 2.4 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.17 EPS31503.1 - 4.4e-06 27.1 14.5 4.4e-06 27.1 14.5 2.3 1 1 1 2 2 2 1 bZIP Maf transcription factor DUF1657 PF07870.11 EPS31503.1 - 0.032 14.1 0.5 0.09 12.7 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1657) FapA PF03961.13 EPS31503.1 - 6.1 5.3 11.9 10 4.6 11.9 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A Exonuc_VII_L PF02601.15 EPS31503.1 - 8.7 5.8 13.1 15 5.0 13.1 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit F-box-like PF12937.7 EPS31504.1 - 1.2e-08 34.7 0.7 4.8e-08 32.8 0.7 2.2 1 0 0 1 1 1 1 F-box-like DUF3760 PF12586.8 EPS31504.1 - 0.09 13.0 0.3 0.23 11.7 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3760) PAN_4 PF14295.6 EPS31505.1 - 0.00011 22.1 1.2 0.00021 21.1 1.2 1.5 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 EPS31505.1 - 0.00041 20.3 0.6 0.00056 19.8 0.6 1.3 1 0 0 1 1 1 1 PAN domain zf-primase PF09329.11 EPS31505.1 - 0.044 13.6 1.2 0.2 11.5 0.8 2.3 2 1 0 2 2 2 0 Primase zinc finger SecIII_SopE_N PF05364.14 EPS31505.1 - 0.099 12.7 0.6 0.2 11.7 0.6 1.5 1 0 0 1 1 1 0 Salmonella type III secretion SopE effector N-terminus Zip PF02535.22 EPS31506.1 - 9.8e-59 199.2 1.5 1.2e-58 198.9 1.5 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter SKG6 PF08693.10 EPS31507.1 - 0.00018 20.8 0.0 0.00032 20.0 0.0 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Sel1 PF08238.12 EPS31508.1 - 1.3e-15 57.5 7.2 7.5e-05 23.3 0.1 3.8 4 0 0 4 4 4 3 Sel1 repeat TPR_6 PF13174.6 EPS31508.1 - 0.0016 18.9 4.6 4.4 8.2 0.1 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat Mt_ATP-synt_B PF05405.14 EPS31509.1 - 9.6e-53 178.1 6.4 1.2e-52 177.8 6.4 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Taxilin PF09728.9 EPS31509.1 - 0.085 12.0 9.0 0.11 11.7 9.0 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein CBF PF03914.17 EPS31510.1 - 3.6e-37 128.0 0.5 8.6e-37 126.8 0.5 1.7 1 0 0 1 1 1 1 CBF/Mak21 family GPI-anchored PF10342.9 EPS31511.1 - 3.6e-15 56.5 0.1 3.6e-15 56.5 0.1 2.4 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF5031 PF16434.5 EPS31511.1 - 0.0029 16.8 0.0 0.006 15.8 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF5031) DUF4689 PF15755.5 EPS31511.1 - 1.1 8.8 8.6 0.55 9.8 5.9 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4689) TFIIA PF03153.13 EPS31511.1 - 4.4 7.2 7.6 5.2 7.0 7.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SHE3 PF17078.5 EPS31512.1 - 4.8e-10 39.5 23.1 9.5e-10 38.6 23.1 1.5 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 Filament PF00038.21 EPS31512.1 - 0.17 11.4 32.6 9.5 5.7 30.7 2.5 1 1 0 1 1 1 0 Intermediate filament protein ADIP PF11559.8 EPS31512.1 - 9 6.4 34.2 1.3 9.1 11.0 3.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding BAT2_N PF07001.11 EPS31513.1 - 0.017 15.6 0.3 0.022 15.2 0.3 1.1 1 0 0 1 1 1 0 BAT2 N-terminus HCV_env PF01539.17 EPS31513.1 - 0.15 11.7 0.8 0.21 11.3 0.2 1.5 2 0 0 2 2 2 0 Hepatitis C virus envelope glycoprotein E1 MMS19_C PF12460.8 EPS31515.1 - 9.5e-119 397.2 18.9 4.5e-118 395.0 9.1 4.2 3 2 0 4 4 4 2 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 EPS31515.1 - 1.4e-94 316.5 0.9 3.4e-93 312.0 0.0 3.1 3 0 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II Cnd1 PF12717.7 EPS31515.1 - 3e-07 30.6 5.4 1.1 9.3 0.0 5.2 4 1 1 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EPS31515.1 - 3e-06 27.5 6.7 0.17 12.3 0.1 6.0 5 2 0 5 5 5 2 HEAT repeats RTP1_C1 PF10363.9 EPS31515.1 - 0.00011 22.3 9.2 0.1 12.8 0.0 4.7 5 0 0 5 5 5 2 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 EPS31515.1 - 0.002 18.6 9.0 1.9 9.1 0.3 5.9 6 0 0 6 6 6 1 HEAT-like repeat HEAT PF02985.22 EPS31515.1 - 0.0048 17.0 14.1 6.6 7.3 0.2 7.5 9 0 0 9 9 9 1 HEAT repeat Arm PF00514.23 EPS31515.1 - 0.38 10.9 7.2 15 5.8 0.0 5.1 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Fasciclin PF02469.22 EPS31516.1 - 1.7e-05 25.1 0.0 3.6e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 Fasciclin domain EMC3_TMCO1 PF01956.16 EPS31517.1 - 2.3e-53 180.4 0.3 3.5e-53 179.8 0.3 1.3 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like DUF4405 PF14358.6 EPS31517.1 - 0.87 10.2 4.9 6.1 7.5 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) SPC25 PF06703.11 EPS31518.1 - 2.5e-49 167.2 0.1 2.9e-49 167.0 0.1 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) MBD PF01429.19 EPS31518.1 - 0.0024 17.5 0.1 0.0049 16.5 0.1 1.4 1 0 0 1 1 1 1 Methyl-CpG binding domain THF_DHG_CYH PF00763.23 EPS31519.1 - 5.8e-26 91.0 0.1 8.4e-26 90.5 0.1 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 EPS31519.1 - 1.5e-12 47.2 0.0 1.3e-10 40.8 0.0 2.6 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF3143 PF11341.8 EPS31519.1 - 0.054 13.9 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3143) CdiI_N PF18228.1 EPS31519.1 - 0.14 12.0 0.1 0.27 11.1 0.1 1.4 1 0 0 1 1 1 0 CdiI N-terminal domain ATP-synt_ab PF00006.25 EPS31521.1 - 6.6e-73 244.9 0.0 9.5e-73 244.4 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 EPS31521.1 - 2e-48 163.8 0.5 3.5e-48 163.1 0.5 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 EPS31521.1 - 8.3e-15 55.1 3.2 2.4e-14 53.6 3.2 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF4404 PF14357.6 EPS31521.1 - 0.12 13.0 0.7 0.4 11.3 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) DUF962 PF06127.11 EPS31522.1 - 7e-25 86.9 1.1 9.7e-25 86.5 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF962) Asr PF06392.11 EPS31522.1 - 0.63 10.5 3.6 1 9.8 3.6 1.3 1 0 0 1 1 1 0 Acid shock protein repeat SHS2_Rpb7-N PF03876.17 EPS31523.1 - 1.1e-14 54.6 0.0 2e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 EPS31523.1 - 2.9e-10 40.3 0.0 4.6e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain Piwi PF02171.17 EPS31527.1 - 6.4e-71 239.1 0.0 9.5e-71 238.5 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 EPS31527.1 - 3.1e-22 79.7 0.0 7.7e-22 78.4 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL2 PF16488.5 EPS31527.1 - 2.3e-14 53.5 0.2 1.2e-13 51.2 0.1 2.3 2 0 0 2 2 2 1 Argonaute linker 2 domain ArgoL1 PF08699.10 EPS31527.1 - 2.8e-10 39.7 0.0 6.8e-10 38.5 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 EPS31527.1 - 8.9e-10 38.5 0.0 2.5e-09 37.0 0.0 1.8 2 0 0 2 2 2 1 PAZ domain ArgoMid PF16487.5 EPS31527.1 - 0.00033 20.9 0.1 0.00072 19.8 0.1 1.6 1 0 0 1 1 1 1 Mid domain of argonaute Fungal_trans PF04082.18 EPS31528.1 - 2.4e-13 49.8 0.1 4.4e-13 48.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS31528.1 - 1.8e-07 31.1 12.2 3.3e-07 30.3 12.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PRCH PF03967.13 EPS31528.1 - 0.021 15.1 0.0 0.048 13.9 0.0 1.5 1 0 0 1 1 1 0 Photosynthetic reaction centre, H-chain N-terminal region HSBP1 PF06825.12 EPS31528.1 - 0.06 13.2 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 RRM_1 PF00076.22 EPS31529.1 - 3.2e-33 113.4 0.3 9.9e-19 66.9 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TRAPPC-Trs85 PF12739.7 EPS31529.1 - 0.0025 16.9 0.5 0.0034 16.4 0.5 1.3 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit RRM_7 PF16367.5 EPS31529.1 - 0.015 15.4 0.0 3.1 8.0 0.0 2.7 2 0 0 2 2 2 0 RNA recognition motif SET_assoc PF11767.8 EPS31529.1 - 0.13 11.9 0.0 0.42 10.3 0.0 1.9 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated Mo25 PF08569.11 EPS31529.1 - 0.16 11.3 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Mo25-like PAPA-1 PF04795.12 EPS31529.1 - 8 7.3 0.0 8 7.3 0.0 3.0 3 0 0 3 3 3 0 PAPA-1-like conserved region TPR_2 PF07719.17 EPS31530.1 - 7.9e-23 78.7 3.1 1.7e-07 30.8 0.1 6.0 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 EPS31530.1 - 1.5e-22 78.4 3.3 2.7e-08 33.3 0.1 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 EPS31530.1 - 7.6e-19 67.1 3.0 5e-09 35.7 0.1 5.0 4 1 1 5 5 5 3 TPR repeat TPR_16 PF13432.6 EPS31530.1 - 1.3e-17 64.2 2.5 3.8e-06 27.4 0.3 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 EPS31530.1 - 2.4e-17 62.1 1.7 7.7e-05 23.2 0.0 5.8 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 EPS31530.1 - 6.8e-15 55.3 3.1 0.00045 20.7 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 EPS31530.1 - 3e-14 52.3 1.0 0.0073 16.6 0.1 5.0 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_8 PF13181.6 EPS31530.1 - 1.2e-13 50.1 1.4 2.6e-06 27.2 0.0 4.8 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_20 PF14561.6 EPS31530.1 - 5.9e-11 42.6 0.6 0.0057 17.0 0.0 4.8 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EPS31530.1 - 6.7e-11 42.3 3.3 8.4e-07 29.2 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EPS31530.1 - 1.2e-10 40.6 1.1 0.0065 16.4 0.0 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 EPS31530.1 - 1.3e-09 38.0 1.1 0.0021 18.2 0.0 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 EPS31530.1 - 1.8e-06 28.2 0.9 1.2 10.0 0.0 5.9 6 0 0 6 6 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EPS31530.1 - 1.1e-05 25.5 2.8 0.00041 20.5 0.7 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 EPS31530.1 - 0.00017 21.5 0.1 0.15 12.1 0.0 2.8 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 EPS31530.1 - 0.00022 20.6 0.4 0.41 9.8 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat MIT PF04212.18 EPS31530.1 - 0.00066 19.7 0.1 4.6 7.4 0.1 4.2 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 EPS31530.1 - 0.022 14.6 6.5 0.06 13.2 0.9 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF1641 PF07849.11 EPS31530.1 - 0.042 13.7 0.4 0.16 11.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1641) TOM20_plant PF06552.12 EPS31530.1 - 0.067 12.9 0.1 2.4 7.9 0.0 3.0 3 1 1 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 DUF3987 PF13148.6 EPS31530.1 - 1.4 7.8 4.3 0.3 10.0 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Methyltransf_28 PF02636.17 EPS31531.1 - 1.3e-39 136.4 0.0 1.8e-39 135.9 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PALP PF00291.25 EPS31532.1 - 3.4e-61 207.2 0.5 4.6e-61 206.8 0.5 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF108 PF01958.18 EPS31532.1 - 0.12 12.8 0.0 0.35 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF108 Scm3 PF10384.9 EPS31533.1 - 3.6e-20 71.4 0.1 8.2e-20 70.3 0.1 1.7 1 0 0 1 1 1 1 Centromere protein Scm3 Myb_DNA-binding PF00249.31 EPS31533.1 - 0.0003 20.9 0.1 0.89 9.8 0.0 3.3 3 0 0 3 3 3 2 Myb-like DNA-binding domain APG6 PF04111.12 EPS31534.1 - 3.7e-73 245.3 0.0 5.7e-73 244.7 0.0 1.3 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 EPS31534.1 - 9.8e-39 132.9 9.3 1.5e-38 132.4 9.3 1.3 1 0 0 1 1 1 1 Apg6 coiled-coil region KASH_CCD PF14662.6 EPS31534.1 - 0.038 13.8 7.9 0.19 11.5 6.5 2.1 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF3829 PF12889.7 EPS31534.1 - 0.22 11.0 2.6 0.31 10.5 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) MbeD_MobD PF04899.12 EPS31534.1 - 0.44 10.7 3.9 1.9 8.6 3.8 2.1 1 1 0 1 1 1 0 MbeD/MobD like HIP1_clath_bdg PF16515.5 EPS31534.1 - 0.64 10.7 7.0 0.11 13.1 1.9 2.2 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DivIC PF04977.15 EPS31534.1 - 0.73 9.6 4.2 1.7 8.4 4.2 1.7 1 0 0 1 1 1 0 Septum formation initiator ERM PF00769.19 EPS31534.1 - 1.6 8.5 10.2 2.7 7.8 10.2 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Seryl_tRNA_N PF02403.22 EPS31534.1 - 1.7 8.9 6.0 2.8 8.2 5.7 1.5 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Jnk-SapK_ap_N PF09744.9 EPS31534.1 - 1.9 8.7 10.4 3.6 7.8 10.4 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF4164 PF13747.6 EPS31534.1 - 2.6 8.4 13.7 0.64 10.3 7.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) CCDC-167 PF15188.6 EPS31534.1 - 5.7 7.4 7.9 1.9 8.9 4.0 2.1 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Spc24 PF08286.11 EPS31534.1 - 6.5 7.1 6.0 15 5.9 6.0 1.6 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 ZapB PF06005.12 EPS31534.1 - 8.7 6.9 14.4 33 5.0 14.3 2.0 1 1 0 1 1 1 0 Cell division protein ZapB Clr5 PF14420.6 EPS31537.1 - 1.9e-15 56.8 4.5 4.8e-15 55.5 4.5 1.7 1 0 0 1 1 1 1 Clr5 domain LysM PF01476.20 EPS31540.1 - 0.0002 21.3 0.0 0.0028 17.7 0.0 2.5 2 0 0 2 2 2 1 LysM domain Glyco_hydro_18 PF00704.28 EPS31542.1 - 5.8e-60 203.6 0.3 1.3e-59 202.5 0.2 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 DNase_NucA_NucB PF14040.6 EPS31542.1 - 0.021 15.2 1.0 0.075 13.4 0.7 2.0 2 0 0 2 2 2 0 Deoxyribonuclease NucA/NucB Prenyltrans PF00432.21 EPS31542.1 - 0.058 13.1 1.1 3.2 7.6 0.1 2.8 2 0 0 2 2 2 0 Prenyltransferase and squalene oxidase repeat LysM PF01476.20 EPS31543.1 - 2.7e-22 78.5 0.5 7.9e-06 25.9 0.0 3.2 3 0 0 3 3 3 3 LysM domain HTH_23 PF13384.6 EPS31543.1 - 0.00039 20.1 0.1 4.4 7.2 0.0 3.2 3 0 0 3 3 3 2 Homeodomain-like domain HTH_28 PF13518.6 EPS31543.1 - 0.051 13.7 0.0 24 5.1 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain Monellin PF09200.10 EPS31543.1 - 0.2 11.6 0.0 38 4.2 0.0 2.6 2 0 0 2 2 2 0 Monellin DNA_ligase_C PF17879.1 EPS31543.1 - 2.4 8.3 5.1 45 4.2 0.2 3.1 3 0 0 3 3 3 0 DNA ligase C-terminal domain Peroxin-13_N PF04088.13 EPS31544.1 - 8.6e-54 181.8 0.3 1.3e-53 181.2 0.3 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.17 EPS31544.1 - 3.1e-09 36.4 0.0 5.5e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EPS31544.1 - 3.1e-08 33.1 0.0 5.2e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EPS31544.1 - 1e-05 25.3 0.1 1.8e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.11 EPS31544.1 - 0.12 12.7 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain hSH3 PF14603.6 EPS31544.1 - 0.13 12.7 0.0 0.22 12.0 0.0 1.3 1 0 0 1 1 1 0 Helically-extended SH3 domain ERO1 PF04137.15 EPS31546.1 - 6.3e-138 459.8 0.0 7.8e-138 459.5 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Pal1 PF08316.11 EPS31549.1 - 2.9e-12 47.5 0.7 4.3e-12 47.0 0.2 1.6 2 0 0 2 2 2 1 Pal1 cell morphology protein HVSL PF09749.9 EPS31551.1 - 9.3e-85 283.9 0.1 1.1e-84 283.7 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein DUF3807 PF12720.7 EPS31552.1 - 1.8e-39 135.9 0.4 2.8e-39 135.3 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) Aa_trans PF01490.18 EPS31553.1 - 3.3e-42 144.6 41.4 4e-42 144.4 41.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SAS4 PF15460.6 EPS31554.1 - 5.5e-30 103.4 8.6 1.4e-29 102.1 8.6 1.7 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 DHDPS PF00701.22 EPS31555.1 - 3.4e-49 167.1 0.0 4e-49 166.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Glyco_hydro_20 PF00728.22 EPS31556.1 - 1e-102 344.1 0.2 1.3e-102 343.8 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 EPS31556.1 - 4.3e-32 111.6 0.1 1e-31 110.5 0.1 1.6 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 EPS31556.1 - 3.6e-05 24.5 0.1 7.2e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Pkinase PF00069.25 EPS31557.1 - 1.6e-28 99.8 0.0 7.3e-28 97.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS31557.1 - 6.1e-08 32.3 1.0 1.7e-06 27.5 1.0 2.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EPS31557.1 - 0.011 14.6 0.1 0.016 14.0 0.1 1.4 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EPS31557.1 - 0.12 12.3 0.1 0.32 10.9 0.1 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family zf-C2H2 PF00096.26 EPS31562.1 - 0.0009 19.6 21.5 0.64 10.6 1.0 5.5 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-met PF12874.7 EPS31562.1 - 0.096 13.1 3.4 2.3 8.8 0.6 3.5 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EPS31562.1 - 0.32 12.0 18.6 1.1 10.2 0.6 5.2 4 1 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EPS31562.1 - 2.1 8.7 8.4 3.7 8.0 0.8 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding ADK_lid PF05191.14 EPS31562.1 - 3.4 7.7 5.3 4.6 7.3 1.9 2.7 2 0 0 2 2 2 0 Adenylate kinase, active site lid ATP_transf PF09830.9 EPS31563.1 - 2.7e-23 81.9 0.0 4.5e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase LtrA PF06772.11 EPS31565.1 - 5.6e-18 65.3 21.7 5.6e-18 65.3 21.7 2.0 2 0 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) HIP1_clath_bdg PF16515.5 EPS31566.1 - 0.045 14.4 1.0 0.045 14.4 1.0 2.8 3 0 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4061 PF13270.6 EPS31566.1 - 1.2 9.5 5.9 26 5.2 0.8 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4061) LSM PF01423.22 EPS31567.1 - 5.2e-22 77.3 0.3 5.8e-22 77.2 0.3 1.0 1 0 0 1 1 1 1 LSM domain Peptidase_M1_N PF17900.1 EPS31568.1 - 0.00023 21.4 0.0 0.58 10.3 0.0 2.4 2 0 0 2 2 2 2 Peptidase M1 N-terminal domain Peptidase_M1 PF01433.20 EPS31568.1 - 0.026 14.1 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M1 domain CDP-OH_P_transf PF01066.21 EPS31569.1 - 1.8e-16 60.6 0.2 1.8e-16 60.6 0.2 3.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase EP400_N PF15790.5 EPS31569.1 - 0.3 9.9 0.0 0.42 9.4 0.0 1.1 1 0 0 1 1 1 0 E1A-binding protein p400, N-terminal ABC_tran PF00005.27 EPS31570.1 - 1.7e-42 145.2 0.0 4.4e-23 82.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EPS31570.1 - 9.6e-33 114.0 25.2 1.8e-27 96.7 9.8 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EPS31570.1 - 1.5e-12 47.5 1.2 0.016 14.7 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EPS31570.1 - 6.8e-08 32.7 4.7 0.58 9.9 0.0 4.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 EPS31570.1 - 1.7e-06 27.3 0.0 0.016 14.3 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.6 EPS31570.1 - 3.4e-06 26.7 0.3 0.013 15.3 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EPS31570.1 - 1.8e-05 25.0 2.2 0.058 13.7 0.0 3.3 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EPS31570.1 - 6.2e-05 23.0 0.1 0.099 12.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase IstB_IS21 PF01695.17 EPS31570.1 - 0.0001 22.1 1.6 0.28 10.9 0.0 3.3 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_33 PF13671.6 EPS31570.1 - 0.00017 21.7 0.4 0.99 9.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EPS31570.1 - 0.00025 21.5 0.0 0.3 11.5 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 EPS31570.1 - 0.00033 20.2 0.0 1.2 8.6 0.0 2.7 3 0 0 3 3 2 2 P-loop containing dynein motor region AAA_23 PF13476.6 EPS31570.1 - 0.0007 20.2 0.2 0.25 11.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 EPS31570.1 - 0.00077 19.5 2.9 0.012 15.7 0.4 2.4 2 0 0 2 2 2 1 Dynamin family AAA_24 PF13479.6 EPS31570.1 - 0.00094 19.0 0.1 0.26 11.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EPS31570.1 - 0.0017 18.9 1.6 5.1 7.7 0.1 3.3 3 0 0 3 3 3 1 AAA domain cobW PF02492.19 EPS31570.1 - 0.0022 17.6 1.1 0.17 11.4 0.1 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 EPS31570.1 - 0.0097 15.7 0.9 3.4 7.4 0.1 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 EPS31570.1 - 0.015 15.0 0.3 1.6 8.4 0.1 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EPS31570.1 - 0.018 14.3 0.1 0.2 10.8 0.0 2.6 2 1 0 2 2 2 0 NB-ARC domain PRK PF00485.18 EPS31570.1 - 0.018 14.8 0.8 0.51 10.0 0.1 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family TsaE PF02367.17 EPS31570.1 - 0.021 14.8 0.1 3.2 7.8 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 EPS31570.1 - 0.021 15.2 0.2 11 6.5 0.1 3.4 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EPS31570.1 - 0.023 14.3 0.1 7.9 6.0 0.0 3.1 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 EPS31570.1 - 0.031 14.4 0.4 1.2 9.3 0.1 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Pox_A32 PF04665.12 EPS31570.1 - 0.04 13.4 0.7 0.35 10.3 0.1 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein NACHT PF05729.12 EPS31570.1 - 0.045 13.7 0.3 11 5.8 0.0 3.1 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.15 EPS31570.1 - 0.051 13.5 1.5 6 6.7 0.0 2.8 3 0 0 3 3 2 0 NTPase SbcCD_C PF13558.6 EPS31570.1 - 0.062 13.5 0.6 15 5.9 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Roc PF08477.13 EPS31570.1 - 0.064 13.5 0.2 16 5.8 0.0 3.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase ATPase_2 PF01637.18 EPS31570.1 - 0.073 13.0 0.4 3.1 7.6 0.0 2.7 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea AAA_11 PF13086.6 EPS31570.1 - 0.14 11.9 0.0 2.4 7.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 EPS31570.1 - 0.15 11.9 0.4 17 5.3 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SOG2 PF10428.9 EPS31572.1 - 0.54 9.4 14.4 0.61 9.2 14.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Miga PF10265.9 EPS31572.1 - 1.4 7.8 4.4 1.6 7.6 4.4 1.1 1 0 0 1 1 1 0 Mitoguardin Macoilin PF09726.9 EPS31572.1 - 1.4 7.4 4.5 1.4 7.4 4.5 1.1 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 EPS31572.1 - 8 5.2 6.8 9.1 5.0 6.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain MS_channel PF00924.18 EPS31573.1 - 2.4e-23 82.8 1.7 4.3e-23 81.9 1.7 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_5 PF13202.6 EPS31573.1 - 0.00048 19.5 0.0 0.0011 18.4 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 EPS31573.1 - 0.0011 18.4 0.2 0.0024 17.3 0.2 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EPS31573.1 - 0.0019 18.0 0.0 0.0049 16.7 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.6 EPS31573.1 - 0.019 15.4 0.3 0.046 14.2 0.3 1.6 1 0 0 1 1 1 0 EF-hand domain pair OmdA PF13376.6 EPS31573.1 - 2.2 8.4 5.6 8.9 6.4 0.9 2.9 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated Pkinase PF00069.25 EPS31576.1 - 1.7e-57 194.8 0.0 9.1e-39 133.4 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EPS31576.1 - 3.6e-28 98.6 0.0 4.8e-20 71.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 EPS31576.1 - 5.2e-12 45.9 0.0 1.1e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 EPS31576.1 - 1e-07 31.6 0.0 1.7e-05 24.3 0.0 2.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EPS31576.1 - 0.00012 22.1 0.1 0.0055 16.6 0.2 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EPS31576.1 - 0.0057 16.0 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EPS31576.1 - 0.0066 15.4 0.0 0.015 14.2 0.0 1.6 1 0 0 1 1 1 1 Haspin like kinase domain PAS_9 PF13426.7 EPS31576.1 - 0.036 14.3 0.0 0.099 12.9 0.0 1.7 1 0 0 1 1 1 0 PAS domain PAS PF00989.25 EPS31576.1 - 0.051 13.6 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 PAS fold RIO1 PF01163.22 EPS31576.1 - 0.094 12.3 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 EPS31576.1 - 0.12 11.4 0.1 0.21 10.6 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 EPS31576.1 - 0.16 11.6 0.0 19 4.8 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 GMC_oxred_N PF00732.19 EPS31577.1 - 3.1e-39 135.1 0.0 7.4e-39 133.9 0.0 1.6 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EPS31577.1 - 4.1e-37 127.9 0.0 6.3e-37 127.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EPS31577.1 - 8.2e-07 28.4 1.9 0.00015 21.0 2.1 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EPS31577.1 - 2.7e-06 27.2 0.8 0.00021 21.0 0.6 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPS31577.1 - 3e-06 26.7 0.1 8.6e-06 25.2 0.2 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EPS31577.1 - 2.1e-05 23.8 0.5 4.8e-05 22.6 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EPS31577.1 - 0.00061 20.0 2.5 0.0019 18.4 2.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EPS31577.1 - 0.0021 16.8 0.2 0.0031 16.3 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 EPS31577.1 - 0.0024 18.4 0.9 0.0074 16.8 0.9 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EPS31577.1 - 0.0028 16.9 0.1 0.13 11.5 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EPS31577.1 - 0.0042 16.5 1.2 0.0082 15.5 1.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EPS31577.1 - 0.0046 16.2 0.4 0.0084 15.4 0.4 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 EPS31577.1 - 0.0056 15.8 1.5 0.0092 15.1 1.5 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EPS31577.1 - 0.037 13.3 0.3 0.063 12.5 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 EPS31577.1 - 0.2 10.5 1.7 0.3 9.9 1.7 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Sugar_tr PF00083.24 EPS31578.1 - 3e-107 359.3 20.6 3.4e-107 359.1 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS31578.1 - 3.2e-25 88.8 21.5 2.6e-24 85.8 14.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 EPS31578.1 - 7.9 6.2 12.5 3.1 7.5 0.7 2.9 3 0 0 3 3 3 0 Ion channel regulatory protein UNC-93 3Beta_HSD PF01073.19 EPS31579.1 - 3e-45 154.4 0.0 5.8e-41 140.3 0.0 2.0 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EPS31579.1 - 1.4e-21 77.1 0.4 9e-21 74.4 0.4 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EPS31579.1 - 2.5e-14 53.4 0.5 2.2e-12 47.1 0.1 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EPS31579.1 - 1.7e-11 43.8 0.0 1.7e-10 40.5 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 EPS31579.1 - 9e-07 28.3 0.1 2.7e-06 26.7 0.1 1.8 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EPS31579.1 - 0.088 11.9 0.0 0.55 9.3 0.0 2.1 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein UQ_con PF00179.26 EPS31580.1 - 1e-32 112.7 0.0 2.5e-13 49.9 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin-conjugating enzyme UEV PF05743.13 EPS31580.1 - 0.00063 19.6 0.1 0.04 13.8 0.0 2.5 2 0 0 2 2 2 1 UEV domain Prok-E2_B PF14461.6 EPS31580.1 - 0.027 14.2 0.0 1.4 8.6 0.0 2.7 2 0 0 2 2 2 0 Prokaryotic E2 family B RhoGAP PF00620.27 EPS31582.1 - 7.4e-36 123.3 0.1 1.4e-35 122.3 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 EPS31582.1 - 2.6e-25 88.4 46.1 1.9e-11 44.0 5.4 4.7 5 0 0 5 5 5 4 LIM domain Desulfoferrod_N PF06397.12 EPS31582.1 - 0.53 10.0 2.4 0.46 10.2 0.3 2.0 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain Nbl1_Borealin_N PF10444.9 EPS31584.1 - 1.2e-19 69.7 2.8 1.9e-19 69.0 2.8 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal DUF5398 PF17376.2 EPS31584.1 - 0.17 12.6 0.1 0.45 11.2 0.0 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5398) VWA_2 PF13519.6 EPS31585.1 - 2.2e-21 76.5 0.1 7.5e-21 74.8 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.14 EPS31585.1 - 3.9e-05 23.5 0.1 5.4e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.28 EPS31585.1 - 7.7e-05 23.0 0.6 0.00012 22.4 0.6 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.20 EPS31585.1 - 0.028 14.3 0.1 0.11 12.4 0.1 2.1 1 0 0 1 1 1 0 Ubiquitin interaction motif PDH PF02153.17 EPS31585.1 - 0.093 11.7 0.1 0.14 11.1 0.1 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase Sybindin PF04099.12 EPS31586.1 - 2.3e-46 157.3 0.0 3.4e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 EPS31586.1 - 1.2e-07 31.9 0.0 1.7e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region ABC2_membrane PF01061.24 EPS31587.1 - 1.7e-91 305.3 59.9 1.1e-46 158.9 27.5 2.6 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 EPS31587.1 - 1.2e-34 119.7 0.0 4.4e-16 59.6 0.0 3.4 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 EPS31587.1 - 4.1e-32 109.9 6.7 8.7e-30 102.5 0.0 3.7 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 EPS31587.1 - 2.8e-18 66.3 0.1 8.4e-18 64.8 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 EPS31587.1 - 8.1e-06 25.2 14.1 8.1e-06 25.2 14.1 2.8 3 0 0 3 3 2 1 ABC-2 family transporter protein AAA_25 PF13481.6 EPS31587.1 - 0.00013 21.6 0.0 0.0011 18.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EPS31587.1 - 0.00038 20.4 0.0 0.043 13.7 0.0 2.8 3 0 0 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 EPS31587.1 - 0.0005 20.5 0.8 0.68 10.3 0.0 2.7 3 0 0 3 3 2 2 AAA ATPase domain AAA_18 PF13238.6 EPS31587.1 - 0.00096 19.7 0.0 0.008 16.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EPS31587.1 - 0.0015 18.7 0.1 0.1 12.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EPS31587.1 - 0.0016 18.1 0.3 0.13 12.1 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.6 EPS31587.1 - 0.0044 17.4 0.2 0.21 12.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EPS31587.1 - 0.0068 16.7 0.2 1.8 8.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.6 EPS31587.1 - 0.012 15.5 0.1 2.9 7.6 0.1 2.7 2 1 1 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 EPS31587.1 - 0.012 15.5 4.2 3.4 7.6 0.2 4.0 4 0 0 4 4 4 0 NACHT domain cobW PF02492.19 EPS31587.1 - 0.012 15.2 1.0 0.1 12.2 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.19 EPS31587.1 - 0.067 12.6 0.0 1.3 8.4 0.0 2.5 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EPS31587.1 - 0.11 12.5 0.0 15 5.7 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.6 EPS31587.1 - 0.12 12.0 1.1 3.9 7.1 0.5 2.4 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EPS31587.1 - 0.21 12.1 0.1 0.43 11.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain DUF3340 PF11818.8 EPS31590.1 - 0.44 10.7 6.1 0.9 9.7 6.1 1.4 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) Alpha-L-AF_C PF06964.12 EPS31591.1 - 4.2e-25 88.8 0.0 1.1e-24 87.4 0.0 1.7 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase C-terminal domain Gmad2 PF10648.9 EPS31591.1 - 0.17 12.1 0.2 0.73 10.1 0.1 2.1 2 0 0 2 2 2 0 Immunoglobulin-like domain of bacterial spore germination CYSTM PF12734.7 EPS31593.1 - 0.076 13.3 75.0 0.37 11.1 54.9 4.6 1 1 1 2 2 2 0 Cysteine-rich TM module stress tolerance zf-BED PF02892.15 EPS31595.1 - 1.1 9.3 5.6 12 6.1 0.5 2.5 2 0 0 2 2 2 0 BED zinc finger F-box PF00646.33 EPS31600.1 - 4.2e-07 29.7 4.8 2.7e-05 23.9 0.2 3.4 3 0 0 3 3 3 2 F-box domain F-box-like PF12937.7 EPS31600.1 - 0.023 14.6 0.6 0.023 14.6 0.6 2.0 2 0 0 2 2 2 0 F-box-like DUF261 PF03196.13 EPS31600.1 - 0.93 9.6 3.1 5.4 7.1 0.2 2.4 1 1 0 2 2 2 0 Protein of unknown function, DUF261 SH3BGR PF04908.15 EPS31601.1 - 0.0006 19.9 0.1 0.0018 18.4 0.0 1.9 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein Ribul_P_3_epim PF00834.19 EPS31602.1 - 6e-61 205.3 0.0 8e-60 201.6 0.0 2.1 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family ThiG PF05690.14 EPS31602.1 - 0.036 13.4 0.1 0.054 12.8 0.1 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Methyltransf_11 PF08241.12 EPS31603.1 - 9.9e-07 29.3 0.0 2.1e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPS31603.1 - 0.0046 17.6 0.0 0.01 16.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Colicin_immun PF09204.10 EPS31603.1 - 0.13 12.8 0.0 0.26 11.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial self-protective colicin-like immunity Methyltransf_12 PF08242.12 EPS31603.1 - 0.19 12.5 0.0 0.43 11.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF2040 PF09745.9 EPS31603.1 - 2.7 8.1 4.9 1.7 8.7 0.1 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 55 (DUF2040) LSM PF01423.22 EPS31604.1 - 4e-17 61.7 0.6 5.1e-17 61.3 0.6 1.1 1 0 0 1 1 1 1 LSM domain LRR_9 PF14580.6 EPS31604.1 - 0.0026 17.3 0.1 0.0033 17.0 0.1 1.2 1 0 0 1 1 1 1 Leucine-rich repeat Hfq PF17209.3 EPS31604.1 - 0.026 14.2 0.1 0.04 13.6 0.1 1.3 1 0 0 1 1 1 0 Hfq protein SM-ATX PF14438.6 EPS31604.1 - 0.038 14.1 0.0 0.048 13.8 0.0 1.3 1 1 0 1 1 1 0 Ataxin 2 SM domain NTP_transf_2 PF01909.23 EPS31604.1 - 0.05 13.9 0.0 0.089 13.1 0.0 1.4 1 1 0 1 1 1 0 Nucleotidyltransferase domain DRMBL PF07522.14 EPS31605.1 - 5.2e-34 116.7 0.0 9.8e-34 115.9 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 EPS31605.1 - 6.4e-06 25.8 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain p450 PF00067.22 EPS31606.1 - 2.6e-99 333.1 0.0 3.2e-99 332.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 OPT PF03169.15 EPS31607.1 - 9.8e-185 615.7 54.3 1.1e-184 615.5 54.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Glyco_hydro_18 PF00704.28 EPS31611.1 - 1.4e-66 225.4 0.1 2.4e-66 224.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 EPS31611.1 - 1.2e-11 44.8 18.3 1.2e-11 44.8 18.3 3.9 4 0 0 4 4 4 2 Chitin recognition protein Glyco_hydro_85 PF03644.13 EPS31611.1 - 0.053 12.9 0.0 0.082 12.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 Chitin_bind_1 PF00187.19 EPS31612.1 - 2.2e-16 60.0 77.0 2.5e-06 27.8 22.4 4.8 4 0 0 4 4 4 3 Chitin recognition protein LysM PF01476.20 EPS31612.1 - 8.8e-09 35.3 0.4 0.0075 16.3 0.0 2.9 3 0 0 3 3 3 2 LysM domain DNA_pol_A_exo1 PF01612.20 EPS31613.1 - 1.1e-10 41.5 0.0 2.6e-10 40.3 0.0 1.6 1 1 0 1 1 1 1 3'-5' exonuclease DNA_pol_B_2 PF03175.13 EPS31613.1 - 0.039 12.8 0.0 0.057 12.3 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral SMP PF04927.12 EPS31614.1 - 2.7e-10 40.6 6.2 6.2e-05 23.4 2.0 3.3 3 0 0 3 3 3 3 Seed maturation protein GFA PF04828.14 EPS31616.1 - 3.2e-25 88.3 0.0 4.6e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.7 EPS31616.1 - 0.17 11.9 4.1 0.96 9.5 0.3 2.5 2 1 0 2 2 2 0 Double zinc ribbon Zn_clus PF00172.18 EPS31617.1 - 6.4e-09 35.8 10.1 2e-08 34.2 10.1 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSDR_N_2 PF13588.6 EPS31619.1 - 0.0014 18.6 0.2 0.0065 16.5 0.2 2.0 1 1 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) ATG22 PF11700.8 EPS31620.1 - 1.4e-180 601.1 9.1 1.6e-180 600.9 9.1 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 EPS31620.1 - 1.6e-06 27.3 45.1 2.9e-06 26.5 21.5 2.8 2 1 0 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 EPS31620.1 - 0.00033 19.3 11.8 0.00033 19.3 11.8 3.0 3 0 0 3 3 3 1 MFS/sugar transport protein Tr-sialidase_C PF11052.8 EPS31620.1 - 4.1 7.6 8.6 1.8 8.7 4.9 2.5 2 0 0 2 2 2 0 Trans-sialidase of Trypanosoma hydrophobic C-terminal Sugar_tr PF00083.24 EPS31621.1 - 2.1e-83 280.7 22.6 2.5e-83 280.5 22.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS31621.1 - 3.3e-24 85.5 32.4 2.6e-21 76.0 26.8 2.6 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.7 EPS31621.1 - 0.0026 16.7 4.1 0.0026 16.7 4.1 2.3 2 0 0 2 2 2 1 MFS_1 like family OppC_N PF12911.7 EPS31621.1 - 3.1 7.8 10.1 13 5.9 3.1 3.7 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C DUF2654 PF10849.8 EPS31622.1 - 0.011 15.9 0.7 0.037 14.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2654) DUF735 PF05246.11 EPS31622.1 - 0.027 14.4 0.0 0.037 14.0 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF735) Glyco_hydro_57 PF03065.15 EPS31622.1 - 0.11 11.7 0.1 0.1 11.8 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 DDE_1 PF03184.19 EPS31623.1 - 8.9e-13 48.3 0.0 1.6e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 EPS31623.1 - 6.3e-11 42.1 3.0 7.6e-11 41.9 0.4 2.3 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.16 EPS31623.1 - 4.3e-05 23.2 1.8 5.3e-05 22.9 0.1 2.0 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_28 PF13518.6 EPS31623.1 - 0.14 12.3 0.1 0.14 12.3 0.1 2.7 4 0 0 4 4 4 0 Helix-turn-helix domain BTB PF00651.31 EPS31624.1 - 0.16 12.2 0.0 0.49 10.7 0.0 1.8 1 1 1 2 2 2 0 BTB/POZ domain TPR_12 PF13424.6 EPS31628.1 - 1.3e-89 294.6 23.6 2.5e-17 62.9 0.2 6.5 2 1 6 8 8 7 7 Tetratricopeptide repeat TPR_10 PF13374.6 EPS31628.1 - 1.2e-69 228.5 0.5 2e-11 43.4 0.0 7.7 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_1 PF00515.28 EPS31628.1 - 4.1e-35 118.2 16.8 2.6e-05 23.8 1.2 7.8 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.6 EPS31628.1 - 2.8e-31 105.2 8.9 7.1e-05 22.6 0.1 9.0 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_MalT PF17874.1 EPS31628.1 - 2e-25 89.9 1.7 3.5e-12 46.4 0.2 3.5 1 1 2 3 3 3 3 MalT-like TPR region TPR_2 PF07719.17 EPS31628.1 - 6.7e-25 85.2 15.2 0.0016 18.4 0.4 8.5 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 EPS31628.1 - 4.4e-21 73.3 12.2 0.028 14.6 0.2 8.2 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 EPS31628.1 - 1.8e-19 68.7 6.1 0.23 12.4 0.0 8.8 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 EPS31628.1 - 5.9e-13 49.2 16.0 0.00016 22.3 1.4 7.9 6 2 1 7 7 5 3 Tetratricopeptide repeat NB-ARC PF00931.22 EPS31628.1 - 2.2e-12 46.7 0.0 3.7e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 EPS31628.1 - 5.6e-07 30.1 0.0 2.4e-06 28.0 0.0 2.2 2 0 0 2 2 1 1 AAA ATPase domain TPR_19 PF14559.6 EPS31628.1 - 5.8e-07 29.9 8.5 0.1 13.1 0.1 6.0 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 EPS31628.1 - 2.6e-06 27.4 1.7 6.7 7.3 0.0 5.7 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF2225 PF09986.9 EPS31628.1 - 5.8e-06 26.2 0.2 0.27 11.0 0.0 3.6 1 1 1 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) 14-3-3 PF00244.20 EPS31628.1 - 2e-05 24.2 0.1 1.9 7.9 0.0 4.2 2 1 1 4 4 4 1 14-3-3 protein PNP_UDP_1 PF01048.20 EPS31628.1 - 3e-05 23.4 0.1 7.9e-05 22.0 0.1 1.7 1 0 0 1 1 1 1 Phosphorylase superfamily TPR_4 PF07721.14 EPS31628.1 - 3.7e-05 23.9 2.4 4.5 8.2 0.0 5.3 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EPS31628.1 - 0.00068 19.3 14.7 1.3 8.8 1.2 6.0 6 0 0 6 6 6 1 TPR repeat TPR_21 PF09976.9 EPS31628.1 - 0.0013 18.5 7.3 5.8 6.6 1.7 5.1 2 1 0 3 3 3 1 Tetratricopeptide repeat-like domain DUF4810 PF16068.5 EPS31628.1 - 0.0033 17.9 6.2 16 6.1 0.2 5.2 3 1 2 5 5 5 0 Domain of unknown function (DUF4810) ATPase_2 PF01637.18 EPS31628.1 - 0.01 15.8 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ANAPC3 PF12895.7 EPS31628.1 - 0.01 16.0 0.1 2.1 8.7 0.0 4.0 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EPS31628.1 - 0.027 15.1 22.4 5.2 7.9 0.3 8.0 8 0 0 8 8 7 0 Tetratricopeptide repeat SNAP PF14938.6 EPS31628.1 - 0.045 13.2 2.2 0.21 11.0 0.4 2.6 3 1 0 3 3 3 0 Soluble NSF attachment protein, SNAP Ubiq_cyt_C_chap PF03981.12 EPS31628.1 - 0.079 13.0 0.1 0.97 9.5 0.0 2.5 1 1 1 2 2 2 0 Ubiquinol-cytochrome C chaperone MIT PF04212.18 EPS31628.1 - 0.17 12.0 4.0 65 3.7 0.0 4.3 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.12 EPS31628.1 - 10 6.3 13.1 0.43 10.6 0.3 4.7 7 0 0 7 7 5 0 Tetratricopeptide repeat GH131_N PF18271.1 EPS31630.1 - 6e-65 219.5 0.6 6e-65 219.5 0.6 1.6 2 0 0 2 2 2 1 Glycoside hydrolase 131 catalytic N-terminal domain PPP4R2 PF09184.11 EPS31630.1 - 0.047 13.3 10.0 0.057 13.0 10.0 1.1 1 0 0 1 1 1 0 PPP4R2 CDC27 PF09507.10 EPS31630.1 - 0.98 8.7 12.5 1.3 8.4 12.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 NOA36 PF06524.12 EPS31630.1 - 1.1 8.5 5.5 2 7.7 5.5 1.5 1 0 0 1 1 1 0 NOA36 protein Nucleo_P87 PF07267.11 EPS31630.1 - 1.6 7.5 9.7 2.3 7.0 9.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 adh_short_C2 PF13561.6 EPS31631.1 - 8.7e-63 212.0 0.2 1e-62 211.8 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPS31631.1 - 2.8e-43 147.6 0.3 3.4e-43 147.4 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPS31631.1 - 2.3e-15 57.0 0.2 3.4e-15 56.4 0.2 1.2 1 0 0 1 1 1 1 KR domain MFS_1 PF07690.16 EPS31635.1 - 6.2e-28 97.7 39.1 8.6e-27 94.0 33.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS31635.1 - 3.1e-06 26.3 16.4 3.1e-06 26.3 16.4 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EPS31635.1 - 4.9e-05 22.0 2.5 8.3e-05 21.2 2.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2208 PF09973.9 EPS31635.1 - 0.15 11.7 1.6 0.25 10.9 0.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) DUF1275 PF06912.11 EPS31636.1 - 1e-44 152.7 16.4 1.2e-44 152.5 16.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) 7TMR-DISM_7TM PF07695.11 EPS31636.1 - 0.21 11.5 11.3 0.027 14.3 3.0 2.2 1 1 1 2 2 2 0 7TM diverse intracellular signalling zf-CCHC PF00098.23 EPS31639.1 - 0.096 12.8 4.7 0.16 12.1 4.7 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_4 PF14392.6 EPS31639.1 - 0.38 10.5 3.4 0.78 9.5 3.4 1.5 1 0 0 1 1 1 0 Zinc knuckle Cupin_1 PF00190.22 EPS31640.1 - 3.6e-39 133.8 0.0 4.4e-19 68.6 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 EPS31640.1 - 1.3e-23 82.5 0.5 8.2e-11 41.5 0.1 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.12 EPS31640.1 - 4.6e-09 35.8 0.0 4e-05 23.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.19 EPS31640.1 - 3.5e-06 27.0 0.1 0.0034 17.3 0.1 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_6 PF12852.7 EPS31640.1 - 0.051 13.3 0.0 14 5.4 0.0 2.4 2 1 0 2 2 2 0 Cupin CENP-C_C PF11699.8 EPS31640.1 - 0.064 13.5 0.0 3.3 8.0 0.0 2.9 3 0 0 3 3 3 0 Mif2/CENP-C like Peptidase_M50B PF13398.6 EPS31641.1 - 4.7e-60 202.7 22.8 5.7e-60 202.4 22.8 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.22 EPS31641.1 - 0.0064 15.8 0.2 0.015 14.6 0.2 1.6 1 0 0 1 1 1 1 Peptidase family M50 Peptidase_M41 PF01434.18 EPS31641.1 - 0.26 11.1 0.1 0.4 10.5 0.1 1.2 1 0 0 1 1 1 0 Peptidase family M41 Patched PF02460.18 EPS31641.1 - 2.5 6.1 6.9 3.9 5.4 6.9 1.2 1 0 0 1 1 1 0 Patched family RTA1 PF04479.13 EPS31642.1 - 4.2e-57 193.1 12.0 4.2e-57 193.1 12.0 1.3 2 0 0 2 2 2 1 RTA1 like protein Retrotran_gag_2 PF14223.6 EPS31644.1 - 7.5e-07 28.9 0.0 1.3e-06 28.1 0.0 1.4 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UDPGT PF00201.18 EPS31645.1 - 5.6e-07 28.7 0.0 9.4e-07 28.0 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UIM PF02809.20 EPS31645.1 - 4.2e-06 26.3 1.8 1.8e-05 24.3 1.8 2.2 1 0 0 1 1 1 1 Ubiquitin interaction motif ATG_C PF09333.11 EPS31645.1 - 0.00099 19.4 0.0 0.004 17.5 0.0 2.0 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Glyco_transf_28 PF03033.20 EPS31645.1 - 0.0081 16.2 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_tran_28_C PF04101.16 EPS31645.1 - 0.01 15.8 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain VPS13_C PF16909.5 EPS31645.1 - 0.12 12.1 1.3 0.32 10.7 0.4 2.1 2 0 0 2 2 2 0 Vacuolar-sorting-associated 13 protein C-terminal rve PF00665.26 EPS31647.1 - 7.4e-05 22.9 0.1 0.00014 22.0 0.1 1.4 1 0 0 1 1 1 1 Integrase core domain REV PF00424.18 EPS31647.1 - 0.046 13.7 0.3 0.095 12.7 0.3 1.6 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) RVT_2 PF07727.14 EPS31648.1 - 3e-20 72.9 0.0 5.2e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cons_hypoth95 PF03602.15 EPS31652.1 - 0.063 12.9 0.0 0.086 12.5 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Pkinase PF00069.25 EPS31654.1 - 8e-32 110.6 0.1 2.2e-28 99.4 0.2 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EPS31654.1 - 9.1e-14 51.4 0.0 1.3e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EPS31654.1 - 3.9e-07 30.3 0.0 0.03 14.3 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EPS31654.1 - 1e-05 25.0 0.0 1.6e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EPS31654.1 - 0.0021 17.7 1.4 0.023 14.3 0.5 2.1 1 1 0 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.22 EPS31654.1 - 0.017 14.7 3.6 0.065 12.8 3.6 1.9 1 1 0 1 1 1 0 RIO1 family CblD PF07434.11 EPS31654.1 - 0.097 11.6 0.0 0.3 10.0 0.0 1.6 2 0 0 2 2 2 0 CblD like pilus biogenesis initiator Kinase-like PF14531.6 EPS31654.1 - 0.1 11.9 0.2 0.29 10.4 0.0 1.6 2 1 0 2 2 2 0 Kinase-like Haspin_kinase PF12330.8 EPS31654.1 - 0.22 10.4 1.6 0.2 10.6 0.2 1.5 2 0 0 2 2 2 0 Haspin like kinase domain Ntox1 PF15500.6 EPS31655.1 - 0.16 12.3 0.0 0.17 12.3 0.0 1.1 1 0 0 1 1 1 0 Putative RNase-like toxin, toxin_1 2OG-FeII_Oxy_3 PF13640.6 EPS31656.1 - 9.9e-10 39.2 0.1 1.7e-08 35.2 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Peptidase_M3 PF01432.20 EPS31657.1 - 1e-109 367.9 0.0 1.4e-109 367.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 YcaO_C PF18381.1 EPS31657.1 - 0.012 15.6 0.3 0.023 14.6 0.3 1.4 1 0 0 1 1 1 0 YcaO cyclodehydratase C-terminal domain Peptidase_M91 PF14891.6 EPS31657.1 - 0.26 11.6 0.7 0.86 9.9 0.1 2.0 2 0 0 2 2 2 0 Effector protein Aldo_ket_red PF00248.21 EPS31658.1 - 1e-11 44.6 0.0 2.6e-11 43.3 0.0 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 EPS31659.1 - 2.1e-14 53.4 0.0 2.3e-14 53.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MIP PF00230.20 EPS31662.1 - 5.6e-45 153.8 6.2 7.1e-45 153.5 6.2 1.1 1 0 0 1 1 1 1 Major intrinsic protein FAM76 PF16046.5 EPS31663.1 - 0.32 10.3 5.2 0.39 10.0 5.2 1.0 1 0 0 1 1 1 0 FAM76 protein Glyco_hydro_71 PF03659.14 EPS31664.1 - 2.4e-127 424.8 0.9 2.4e-127 424.8 0.9 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 71 Sde2_N_Ubi PF13019.6 EPS31664.1 - 2.2 8.1 5.3 3.9 7.3 5.3 1.3 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain SSFA2_C PF14723.6 EPS31664.1 - 3.8 7.4 5.1 7 6.5 5.1 1.3 1 0 0 1 1 1 0 Sperm-specific antigen 2 C-terminus FAM220 PF15487.6 EPS31665.1 - 9.1 5.8 12.4 0.063 12.9 0.5 2.7 3 0 0 3 3 3 0 FAM220 family ADH_N PF08240.12 EPS31666.1 - 2.8e-23 81.9 0.1 5.3e-23 81.0 0.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPS31666.1 - 5.5e-15 55.5 0.0 7.9e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EPS31666.1 - 1.5e-06 27.8 0.0 2.5e-06 27.2 0.0 1.3 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus DUF3433 PF11915.8 EPS31667.1 - 1.9e-32 111.5 15.1 9.5e-18 64.5 3.7 4.0 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) Pyr_redox_2 PF07992.14 EPS31668.1 - 2.4e-13 50.0 0.0 4.5e-13 49.1 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EPS31668.1 - 0.0022 17.2 0.0 0.18 10.9 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EPS31668.1 - 0.0091 16.0 0.2 3 7.8 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding HI0933_like PF03486.14 EPS31668.1 - 0.031 13.0 0.0 0.076 11.7 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.22 EPS31668.1 - 0.049 12.7 0.0 5.5 5.9 0.0 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.17 EPS31668.1 - 0.055 12.7 0.1 0.1 11.8 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Methyltransf_2 PF00891.18 EPS31670.1 - 4.1e-20 72.0 0.0 7.1e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 EPS31670.1 - 0.071 13.1 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Dimerisation domain Dimerisation PF08100.11 EPS31670.1 - 0.22 11.6 2.3 0.52 10.4 0.7 2.5 2 2 0 2 2 2 0 Dimerisation domain AP_endonuc_2 PF01261.24 EPS31671.1 - 1.7e-27 96.2 0.4 2.4e-27 95.7 0.4 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel AMP-binding PF00501.28 EPS31673.1 - 1.8e-31 109.2 0.0 3.5e-31 108.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EPS31673.1 - 8.6e-30 103.7 0.0 1.4e-29 103.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EPS31673.1 - 7e-14 51.9 0.0 1.1e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EPS31673.1 - 9.9e-06 25.8 0.1 2.3e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 EPS31673.1 - 0.0001 21.8 0.0 0.00083 18.8 0.0 2.4 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EPS31673.1 - 0.02 14.1 0.0 0.037 13.2 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein KR PF08659.10 EPS31673.1 - 0.022 14.7 0.1 0.097 12.6 0.1 2.0 1 1 0 1 1 1 0 KR domain DapB_N PF01113.20 EPS31673.1 - 0.041 14.0 0.0 0.19 11.9 0.0 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.13 EPS31673.1 - 0.081 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.17 EPS31673.1 - 0.099 11.7 0.0 5.9 5.9 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain NAD_binding_10 PF13460.6 EPS31673.1 - 0.13 12.2 0.0 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 NAD(P)H-binding Semialdhyde_dh PF01118.24 EPS31673.1 - 0.14 12.6 0.0 0.4 11.1 0.0 1.8 2 0 0 2 2 1 0 Semialdehyde dehydrogenase, NAD binding domain STAT6_C PF14596.6 EPS31673.1 - 0.15 12.1 0.0 0.31 11.0 0.0 1.4 1 0 0 1 1 1 0 STAT6 C-terminal Glyco_hydro_16 PF00722.21 EPS31674.1 - 2.4e-06 27.1 0.4 7.2e-06 25.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Hemerythrin PF01814.23 EPS31676.1 - 2.9e-12 47.3 0.8 3.7e-12 47.0 0.8 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Zn_clus PF00172.18 EPS31678.1 - 0.00036 20.6 7.9 0.00067 19.7 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Opy2 PF09463.10 EPS31678.1 - 1.7 9.0 9.6 0.58 10.5 3.9 2.4 1 1 1 2 2 2 0 Opy2 protein PRK PF00485.18 EPS31679.1 - 2e-07 31.0 0.0 2e-06 27.7 0.0 2.0 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.6 EPS31679.1 - 2.1e-06 28.0 0.0 0.00023 21.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EPS31679.1 - 1.7e-05 25.4 0.0 9.5e-05 23.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EPS31679.1 - 0.00019 21.9 0.1 0.00024 21.6 0.1 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EPS31679.1 - 0.00025 21.4 0.0 0.00043 20.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EPS31679.1 - 0.00042 20.7 0.0 0.00061 20.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 EPS31679.1 - 0.00054 19.3 0.0 0.0014 18.0 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.12 EPS31679.1 - 0.0018 18.2 0.0 0.0028 17.6 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_17 PF13207.6 EPS31679.1 - 0.0019 18.6 0.0 0.016 15.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EPS31679.1 - 0.0024 17.6 0.1 0.0043 16.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 EPS31679.1 - 0.0041 17.0 0.0 0.05 13.5 0.0 2.2 2 0 0 2 2 2 1 Adenylylsulphate kinase T2SSE PF00437.20 EPS31679.1 - 0.0043 16.2 0.0 0.0066 15.5 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 EPS31679.1 - 0.0074 16.6 0.0 0.014 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 EPS31679.1 - 0.0079 15.7 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Viral_helicase1 PF01443.18 EPS31679.1 - 0.013 15.2 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.22 EPS31679.1 - 0.013 14.7 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain SRP54 PF00448.22 EPS31679.1 - 0.024 14.3 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF2075 PF09848.9 EPS31679.1 - 0.035 13.4 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MeaB PF03308.16 EPS31679.1 - 0.037 13.0 0.0 0.052 12.5 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 EPS31679.1 - 0.04 13.8 0.0 0.065 13.1 0.0 1.3 1 0 0 1 1 1 0 NTPase ABC_tran PF00005.27 EPS31679.1 - 0.041 14.4 0.0 0.13 12.8 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Thymidylate_kin PF02223.17 EPS31679.1 - 0.042 13.5 0.1 0.29 10.8 0.0 2.0 2 0 0 2 2 2 0 Thymidylate kinase AAA_11 PF13086.6 EPS31679.1 - 0.059 13.2 0.0 0.077 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 EPS31679.1 - 0.089 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DnaB_C PF03796.15 EPS31679.1 - 0.11 11.8 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain TsaE PF02367.17 EPS31679.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 EPS31679.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 EPS31679.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain ATP_bind_1 PF03029.17 EPS31679.1 - 0.15 11.8 0.0 0.37 10.5 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 EPS31679.1 - 0.18 11.3 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region GFA PF04828.14 EPS31680.1 - 4.7e-20 71.7 1.0 7.3e-20 71.1 1.0 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DUF333 PF03891.15 EPS31680.1 - 0.1 12.8 1.7 0.19 12.0 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF333) RNA_POL_M_15KD PF02150.16 EPS31680.1 - 0.61 10.0 5.9 4.9 7.1 0.7 2.5 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit IF-2B PF01008.17 EPS31681.1 - 2.2e-22 79.6 0.0 5.1e-22 78.4 0.0 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family NUDIX PF00293.28 EPS31681.1 - 6.4e-13 48.9 0.1 1.1e-12 48.1 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain Abhydrolase_1 PF00561.20 EPS31682.1 - 4.4e-21 75.7 0.0 2.7e-19 69.8 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPS31682.1 - 8.4e-11 42.9 0.2 1.2e-10 42.4 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPS31682.1 - 6.9e-09 35.3 0.0 2.6e-08 33.4 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Esterase PF00756.20 EPS31682.1 - 0.0015 18.3 0.0 0.0021 17.7 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 EPS31682.1 - 0.01 16.0 0.0 0.075 13.1 0.0 2.1 1 1 0 1 1 1 0 Thioesterase domain Ndr PF03096.14 EPS31682.1 - 0.028 13.1 0.0 0.24 10.1 0.0 1.9 2 0 0 2 2 2 0 Ndr family Abhydrolase_3 PF07859.13 EPS31682.1 - 0.043 13.7 0.0 0.093 12.6 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF915 PF06028.11 EPS31682.1 - 0.063 12.6 0.0 0.095 12.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Palm_thioest PF02089.15 EPS31682.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Kinesin PF00225.23 EPS31683.1 - 3.3e-105 351.7 0.3 3.3e-105 351.7 0.3 2.5 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 EPS31683.1 - 6.2e-61 204.7 0.1 3.3e-60 202.3 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding Cnn_1N PF07989.11 EPS31683.1 - 0.011 15.8 2.9 0.011 15.8 2.9 4.6 3 1 1 4 4 4 0 Centrosomin N-terminal motif 1 AAA_16 PF13191.6 EPS31683.1 - 0.4 11.1 0.0 0.4 11.1 0.0 2.9 2 1 0 3 3 3 0 AAA ATPase domain TSC22 PF01166.18 EPS31683.1 - 0.48 10.8 7.1 0.092 13.1 1.4 2.9 2 1 1 3 3 3 0 TSC-22/dip/bun family Mt_ATP-synt_D PF05873.12 EPS31683.1 - 1.5 8.6 8.6 2.9 7.7 7.1 2.2 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Stm1_N PF09598.10 EPS31683.1 - 4.3 8.2 5.8 9.9 7.1 0.0 2.7 2 0 0 2 2 2 0 Stm1 TPR_MLP1_2 PF07926.12 EPS31683.1 - 7.6 6.6 40.7 2.6 8.1 12.1 3.8 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein DUF1899 PF08953.11 EPS31685.1 - 4.6e-34 116.1 0.0 1.1e-33 114.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 EPS31685.1 - 7e-21 73.9 0.5 1.4e-20 72.9 0.5 1.5 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 EPS31685.1 - 1.7e-16 60.3 7.7 0.00033 21.4 0.2 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS31685.1 - 1.7e-06 28.2 0.0 0.072 13.4 0.1 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EPS31685.1 - 0.0017 17.1 0.4 0.28 9.8 0.3 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 SlyX PF04102.12 EPS31685.1 - 0.081 13.6 1.2 0.19 12.4 1.2 1.6 1 0 0 1 1 1 0 SlyX PNTB PF02233.16 EPS31688.1 - 0.53 9.1 5.3 0.65 8.9 5.3 1.0 1 0 0 1 1 1 0 NAD(P) transhydrogenase beta subunit Oxidored_q3 PF00499.20 EPS31691.1 - 0.034 13.9 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Baculo_11_kDa PF06143.11 EPS31691.1 - 0.035 13.7 0.5 0.082 12.5 0.5 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family CBM_1 PF00734.18 EPS31692.1 - 8.4e-10 38.4 15.9 8.4e-10 38.4 15.9 3.2 3 0 0 3 3 3 1 Fungal cellulose binding domain Peptidase_S9 PF00326.21 EPS31692.1 - 1.3e-07 31.3 0.1 2.7e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 EPS31692.1 - 0.00017 21.3 0.6 0.00048 19.8 0.6 1.7 1 1 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 EPS31692.1 - 0.00018 21.4 0.0 0.0003 20.7 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase_phd PF10503.9 EPS31692.1 - 0.00019 21.0 0.0 0.0003 20.3 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_1 PF00561.20 EPS31692.1 - 0.0017 18.0 0.1 0.0036 17.0 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Rhodanese PF00581.20 EPS31693.1 - 2.3e-17 63.5 0.0 1.8e-11 44.5 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain Zn_clus PF00172.18 EPS31694.1 - 1.8e-11 43.9 7.4 3.7e-11 42.9 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPS31694.1 - 3.6e-10 39.3 0.4 6.3e-10 38.5 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Metallophos PF00149.28 EPS31695.1 - 7.6e-10 39.6 0.2 9.6e-10 39.3 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Elicitin PF00964.17 EPS31695.1 - 0.11 12.6 1.3 3.9 7.6 0.1 2.3 2 0 0 2 2 2 0 Elicitin zf-C3HC4_3 PF13920.6 EPS31696.1 - 0.00078 19.3 12.1 0.0013 18.5 12.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ribosomal_S20p PF01649.18 EPS31696.1 - 0.046 14.4 2.0 0.22 12.2 2.0 2.2 1 0 0 1 1 1 0 Ribosomal protein S20 CBFD_NFYB_HMF PF00808.23 EPS31697.1 - 1.6e-15 57.1 2.5 2.6e-15 56.5 2.5 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EPS31697.1 - 5.8e-06 26.7 0.1 1.1e-05 25.7 0.1 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 RAI16-like PF10257.9 EPS31698.1 - 3.2e-86 289.4 0.0 4.9e-86 288.9 0.0 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein MFS_1 PF07690.16 EPS31699.1 - 1.5e-15 57.0 22.3 1.5e-15 57.0 22.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EPS31699.1 - 0.0054 15.1 0.1 0.0054 15.1 0.1 2.1 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Acyltransferase PF01553.21 EPS31700.1 - 0.0062 16.2 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase ILVD_EDD PF00920.21 EPS31701.1 - 1.6e-208 693.5 0.6 1.9e-208 693.3 0.6 1.0 1 0 0 1 1 1 1 Dehydratase family 5_nucleotid_C PF02872.18 EPS31701.1 - 0.037 14.2 0.1 0.11 12.7 0.0 1.8 2 0 0 2 2 2 0 5'-nucleotidase, C-terminal domain Pkinase PF00069.25 EPS31702.1 - 1.4e-44 152.4 0.0 4.2e-43 147.6 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS31702.1 - 8.1e-27 94.1 0.0 1.4e-26 93.4 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EPS31702.1 - 0.00062 18.7 0.0 0.001 17.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EPS31702.1 - 0.0073 15.6 0.0 0.019 14.3 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Fungal_trans_2 PF11951.8 EPS31703.1 - 1.4e-41 142.6 1.6 2.2e-41 141.9 1.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS31703.1 - 7.5e-11 42.0 6.7 1.4e-10 41.1 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tim17 PF02466.19 EPS31704.1 - 1.4e-25 89.8 5.6 1.9e-25 89.4 5.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF2428 PF10350.9 EPS31705.1 - 5e-65 219.5 0.0 1e-64 218.5 0.0 1.6 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 EPS31705.1 - 0.0061 16.7 5.0 5 7.7 0.1 5.9 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.6 EPS31705.1 - 0.017 15.5 2.9 6.6 7.2 0.1 4.5 4 1 0 4 4 4 0 HEAT repeats HEAT_EZ PF13513.6 EPS31705.1 - 0.05 14.1 5.5 3.2 8.3 0.0 5.3 5 0 0 5 5 5 0 HEAT-like repeat PX PF00787.24 EPS31707.1 - 1.4e-19 70.1 0.1 3.6e-18 65.6 0.0 2.7 2 1 0 2 2 2 1 PX domain Vps5 PF09325.10 EPS31707.1 - 1.9e-06 27.6 10.8 0.0057 16.2 1.4 2.2 2 0 0 2 2 2 2 Vps5 C terminal like Peptidase_C10 PF01640.17 EPS31707.1 - 0.012 16.0 0.0 0.037 14.3 0.0 1.7 2 0 0 2 2 2 0 Peptidase C10 family Glyco_hydro_43 PF04616.14 EPS31708.1 - 3.1e-36 125.2 0.4 4.5e-36 124.6 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 UCH PF00443.29 EPS31709.1 - 7e-63 212.5 0.0 9.9e-63 212.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EPS31709.1 - 3.2e-13 50.1 0.0 8.5e-13 48.7 0.0 1.8 1 0 0 1 1 1 1 DUSP domain UCH_1 PF13423.6 EPS31709.1 - 3.2e-08 33.5 0.0 0.00056 19.6 0.0 2.9 2 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Zn_clus PF00172.18 EPS31710.1 - 0.4 10.8 27.4 0.97 9.6 0.1 4.6 3 1 1 4 4 4 0 Fungal Zn(2)-Cys(6) binuclear cluster domain APG17 PF04108.12 EPS31711.1 - 4.1e-136 454.2 5.9 4.8e-136 454.0 5.9 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 FliD_N PF02465.18 EPS31711.1 - 0.092 13.5 1.5 3.6 8.3 0.5 3.1 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus YkyA PF10368.9 EPS31711.1 - 0.42 10.3 4.0 1.8 8.2 0.3 2.9 2 1 0 2 2 2 0 Putative cell-wall binding lipoprotein Seryl_tRNA_N PF02403.22 EPS31711.1 - 0.58 10.4 5.2 4.7 7.5 1.0 2.9 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HisKA_2 PF07568.12 EPS31711.1 - 0.82 9.8 5.1 1 9.5 0.4 3.1 3 1 0 3 3 3 0 Histidine kinase ERM PF00769.19 EPS31711.1 - 1 9.1 10.5 0.31 10.8 3.2 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF4795 PF16043.5 EPS31711.1 - 1.3 8.6 4.9 1 8.9 0.3 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) AATF-Che1 PF13339.6 EPS31711.1 - 1.6 9.4 4.2 4.3 8.0 1.1 2.6 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor RasGAP_C PF03836.15 EPS31711.1 - 6 7.0 9.8 15 5.7 1.0 3.8 3 2 1 4 4 4 0 RasGAP C-terminus RIO1 PF01163.22 EPS31712.1 - 2e-73 246.0 0.0 2e-73 246.0 0.0 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 EPS31712.1 - 0.0026 17.7 0.0 0.065 13.1 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EPS31712.1 - 0.011 15.1 0.3 0.2 11.0 0.3 2.3 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SMC_N PF02463.19 EPS31713.1 - 1.8e-72 243.3 0.8 3.2e-72 242.5 0.8 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EPS31713.1 - 4.2e-32 110.9 0.0 1.8e-31 108.9 0.0 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 EPS31713.1 - 8.6e-19 68.8 4.1 8.6e-19 68.8 4.1 7.1 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.6 EPS31713.1 - 2.2e-17 63.8 4.6 1.1e-09 38.6 0.0 3.4 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EPS31713.1 - 8.4e-17 61.9 40.5 1.2e-11 44.9 7.7 4.0 2 2 0 3 3 3 2 AAA ATPase domain APG6_N PF17675.1 EPS31713.1 - 0.0048 17.4 12.9 0.0048 17.4 12.9 8.7 2 2 5 8 8 8 3 Apg6 coiled-coil region AAA_29 PF13555.6 EPS31713.1 - 0.0055 16.4 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MeaB PF03308.16 EPS31713.1 - 0.73 8.8 4.6 0.74 8.7 1.2 2.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 EPS31713.1 - 2.9 7.9 0.0 2.9 7.9 0.0 6.8 3 2 1 4 4 4 0 Helicase HerA, central domain DUF3605 PF12239.8 EPS31714.1 - 4.7e-58 195.9 0.0 6e-58 195.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) APOBEC_N PF08210.11 EPS31714.1 - 0.085 12.7 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain FAD_binding_6 PF00970.24 EPS31715.1 - 1.5e-33 115.1 0.0 2.3e-33 114.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EPS31715.1 - 1.3e-27 96.5 0.0 3.7e-27 95.1 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EPS31715.1 - 3.2e-06 27.3 0.0 0.00066 19.8 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 EPS31715.1 - 0.049 13.9 0.0 0.09 13.0 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain MFS_1 PF07690.16 EPS31717.1 - 9.9e-17 60.9 56.3 5.4e-16 58.5 48.7 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EPS31717.1 - 2e-12 46.3 16.8 2e-12 46.3 16.8 1.6 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF3176 PF11374.8 EPS31717.1 - 0.66 10.2 15.4 2.8 8.2 0.8 4.7 2 2 2 4 4 4 0 Protein of unknown function (DUF3176) Pox_A14 PF05767.12 EPS31717.1 - 9.7 6.4 16.4 0.17 12.1 1.7 3.9 2 2 2 4 4 4 0 Poxvirus virion envelope protein A14 PIP5K PF01504.18 EPS31721.1 - 5e-40 137.4 0.0 1.3e-37 129.5 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase PHF12_MRG_bd PF16737.5 EPS31721.1 - 0.073 12.8 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 PHD finger protein 12 MRG binding domain tRNA-synt_1d PF00750.19 EPS31722.1 - 5e-98 328.3 5.3 2.7e-97 325.8 5.3 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 EPS31722.1 - 5.6e-27 94.3 0.2 5.6e-27 94.3 0.2 1.8 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 EPS31722.1 - 7.5e-09 36.1 0.2 2.8e-08 34.2 0.0 2.1 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain ABC2_membrane PF01061.24 EPS31723.1 - 2.3e-28 99.0 28.8 3.6e-28 98.4 28.8 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EPS31723.1 - 4.5e-26 92.0 0.0 8.2e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 EPS31723.1 - 4e-06 26.8 0.2 4.3e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EPS31723.1 - 9.9e-06 26.0 0.1 1.7e-05 25.3 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 EPS31723.1 - 0.0004 20.3 0.2 0.36 10.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 EPS31723.1 - 0.00069 19.6 0.0 0.0015 18.5 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_25 PF13481.6 EPS31723.1 - 0.0007 19.2 0.5 0.0012 18.4 0.0 1.6 2 0 0 2 2 1 1 AAA domain SMC_N PF02463.19 EPS31723.1 - 0.0031 17.0 0.0 0.027 13.9 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 EPS31723.1 - 0.0035 17.6 0.1 0.0066 16.7 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EPS31723.1 - 0.0046 17.2 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EPS31723.1 - 0.0063 16.7 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EPS31723.1 - 0.0075 16.7 0.1 0.054 13.9 0.1 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EPS31723.1 - 0.015 15.8 0.0 0.03 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EPS31723.1 - 0.024 14.4 0.1 0.048 13.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EPS31723.1 - 0.024 14.6 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 EPS31723.1 - 0.026 14.3 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein MMR_HSR1 PF01926.23 EPS31723.1 - 0.028 14.5 0.1 0.065 13.3 0.1 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.12 EPS31723.1 - 0.04 13.8 0.0 0.094 12.6 0.0 1.6 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 EPS31723.1 - 0.053 13.4 0.0 0.099 12.5 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea SRP54 PF00448.22 EPS31723.1 - 0.069 12.8 0.1 0.16 11.5 0.1 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_29 PF13555.6 EPS31723.1 - 0.07 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 EPS31723.1 - 0.071 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain CEP170_C PF15308.6 EPS31723.1 - 0.085 11.4 0.4 0.14 10.7 0.4 1.2 1 0 0 1 1 1 0 CEP170 C-terminus RNA_helicase PF00910.22 EPS31723.1 - 0.096 13.1 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_13 PF13166.6 EPS31723.1 - 0.1 11.2 0.1 0.25 9.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain MeaB PF03308.16 EPS31723.1 - 0.1 11.5 0.1 0.18 10.8 0.1 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_14 PF13173.6 EPS31723.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EPS31723.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 EPS31723.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 EPS31723.1 - 0.17 11.6 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC2_membrane_3 PF12698.7 EPS31723.1 - 0.19 10.8 24.2 0.36 9.9 24.2 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein Epimerase PF01370.21 EPS31726.1 - 1.1e-19 70.8 0.0 2e-19 70.0 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EPS31726.1 - 1e-12 48.1 0.0 2.5e-12 46.8 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EPS31726.1 - 1.5e-12 47.2 0.0 2e-08 33.7 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.19 EPS31726.1 - 5.2e-12 45.4 0.0 9.7e-12 44.5 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EPS31726.1 - 2.4e-07 30.8 0.1 4.6e-07 29.9 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 EPS31726.1 - 6.2e-06 25.9 0.0 1.7e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 EPS31726.1 - 0.00025 20.3 0.0 0.00055 19.2 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EPS31726.1 - 0.036 13.2 0.0 0.37 9.8 0.0 2.2 1 1 0 1 1 1 0 RmlD substrate binding domain adh_short PF00106.25 EPS31726.1 - 0.063 12.7 0.1 0.17 11.4 0.0 1.9 2 1 0 2 2 2 0 short chain dehydrogenase KR PF08659.10 EPS31726.1 - 0.066 13.1 1.1 11 5.9 0.1 2.4 2 1 0 2 2 2 0 KR domain Lin-8 PF03353.15 EPS31728.1 - 0.0081 15.8 6.1 0.046 13.3 6.5 1.8 1 1 1 2 2 2 1 Ras-mediated vulval-induction antagonist DUF2165 PF09933.9 EPS31728.1 - 0.15 12.1 1.2 0.23 11.5 1.2 1.2 1 0 0 1 1 1 0 Predicted small integral membrane protein (DUF2165) FixS PF03597.15 EPS31728.1 - 8.4 6.2 5.8 16 5.3 5.8 1.4 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type Retrotran_gag_2 PF14223.6 EPS31729.1 - 1.1e-05 25.2 0.0 1.7e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Acetyltransf_2 PF00797.17 EPS31730.1 - 1.8e-34 119.6 0.0 2.2e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase Methyltr_RsmF_N PF17125.5 EPS31730.1 - 0.11 13.0 0.0 0.21 12.1 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of 16S rRNA methyltransferase RsmF MWFE PF15879.5 EPS31731.1 - 7.2e-28 96.5 0.3 8.9e-28 96.2 0.3 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit MOZ_SAS PF01853.18 EPS31732.1 - 2e-73 245.9 0.0 3.2e-73 245.2 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EPS31732.1 - 6.5e-21 73.7 4.2 6.5e-21 73.7 4.2 1.7 2 0 0 2 2 2 1 MYST family zinc finger domain PHD_4 PF16866.5 EPS31732.1 - 5.5e-10 39.2 9.6 1.4e-09 37.9 9.6 1.7 1 0 0 1 1 1 1 PHD-finger PHD PF00628.29 EPS31732.1 - 0.0057 16.5 11.1 0.0057 16.5 11.1 2.1 2 0 0 2 2 2 1 PHD-finger Acetyltransf_7 PF13508.7 EPS31732.1 - 0.14 12.6 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-DNL PF05180.12 EPS31732.1 - 0.17 11.8 0.9 0.42 10.6 0.9 1.6 1 0 0 1 1 1 0 DNL zinc finger zf-RING_9 PF13901.6 EPS31732.1 - 0.19 11.7 6.3 0.36 10.8 6.3 1.3 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon DEADboxA PF12343.8 EPS31733.1 - 0.78 10.3 9.0 1.7 9.3 4.1 2.4 1 1 1 2 2 2 0 Cold shock protein DEAD box A Velvet PF11754.8 EPS31735.1 - 2.5e-41 142.3 5.9 1.1e-31 110.7 0.4 3.4 2 2 1 3 3 3 2 Velvet factor AAA_18 PF13238.6 EPS31737.1 - 0.00066 20.2 0.0 0.001 19.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain PRK PF00485.18 EPS31737.1 - 0.0025 17.6 0.4 0.004 16.9 0.4 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family ABC_tran PF00005.27 EPS31737.1 - 0.0074 16.8 0.1 0.079 13.5 0.1 2.2 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 EPS31737.1 - 0.017 15.5 0.3 0.027 14.8 0.3 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 EPS31737.1 - 0.043 14.1 0.2 0.085 13.1 0.2 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EPS31737.1 - 0.053 13.4 0.0 0.083 12.8 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain CPT PF07931.12 EPS31737.1 - 0.054 13.3 0.3 0.094 12.6 0.3 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_23 PF13476.6 EPS31737.1 - 0.17 12.4 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain zf-met PF12874.7 EPS31738.1 - 1.7e-09 37.7 13.7 0.00038 20.7 0.1 4.7 4 0 0 4 4 4 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EPS31738.1 - 3.2e-06 27.3 20.7 0.0037 17.5 0.1 5.1 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EPS31738.1 - 0.00039 21.0 22.2 3.4 8.7 1.0 6.1 6 0 0 6 6 6 4 C2H2-type zinc finger zf-C2H2_2 PF12756.7 EPS31738.1 - 0.012 16.0 21.7 1.1 9.7 0.1 5.0 2 2 2 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 EPS31738.1 - 0.17 12.4 33.0 1.6 9.3 0.2 6.0 6 1 0 6 6 6 0 Zinc finger, C2H2 type VATC PF18716.1 EPS31738.1 - 0.69 9.8 0.1 0.69 9.8 0.1 4.0 3 2 1 4 4 4 0 Vms1-associating treble clef domain zf-C2H2 PF00096.26 EPS31739.1 - 1.1e-06 28.8 24.2 0.19 12.3 2.3 4.8 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPS31739.1 - 0.0002 21.9 22.6 0.51 11.3 0.2 5.3 4 1 1 5 5 5 3 C2H2-type zinc finger zf-Di19 PF05605.12 EPS31739.1 - 0.00081 19.6 0.2 0.00081 19.6 0.2 3.5 4 0 0 4 4 4 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 EPS31739.1 - 0.00085 19.6 12.9 0.27 11.6 0.0 3.9 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EPS31739.1 - 0.0028 17.9 10.9 1.1 9.6 1.5 4.1 3 1 1 4 4 4 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 EPS31739.1 - 0.0035 17.7 8.2 3.4 8.2 0.0 3.5 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.6 EPS31739.1 - 0.0049 16.7 4.2 0.0076 16.1 0.1 2.9 3 0 0 3 3 2 1 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.10 EPS31739.1 - 0.011 15.9 0.9 0.011 15.9 0.9 3.0 3 0 0 3 3 3 0 Zinc ribbon domain DUF4187 PF13821.6 EPS31739.1 - 0.066 13.0 2.8 0.21 11.4 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4187) zf-C2H2_6 PF13912.6 EPS31739.1 - 0.14 12.2 20.0 2.3 8.3 2.0 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger DZR PF12773.7 EPS31739.1 - 0.44 10.6 5.0 2.3 8.3 1.0 2.6 2 1 0 2 2 2 0 Double zinc ribbon zf-C2H2_8 PF15909.5 EPS31739.1 - 0.47 10.8 4.7 5.5 7.3 0.3 2.7 2 1 0 2 2 2 0 C2H2-type zinc ribbon zinc_ribbon_9 PF14369.6 EPS31739.1 - 1.2 9.4 0.0 1.2 9.4 0.0 3.5 4 0 0 4 4 4 0 zinc-ribbon DUF2256 PF10013.9 EPS31739.1 - 2.5 8.3 7.0 20 5.4 0.3 3.4 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) FOXP-CC PF16159.5 EPS31739.1 - 2.9 8.6 7.2 71 4.1 0.5 3.6 2 2 1 3 3 3 0 FOXP coiled-coil domain zf_UBZ PF18439.1 EPS31739.1 - 3 7.5 8.6 4.3 7.0 1.3 3.2 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-H2C2_2 PF13465.6 EPS31739.1 - 3.5 8.2 14.7 9.9 6.8 0.4 4.6 4 0 0 4 4 4 0 Zinc-finger double domain zf-CHCC PF10276.9 EPS31739.1 - 5.5 7.1 7.2 8.4 6.5 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger domain zf-C2H2_9 PF16293.5 EPS31739.1 - 8.9 6.2 12.3 11 5.9 0.7 4.1 4 1 0 4 4 4 0 C2H2 type zinc-finger (1 copy) SNF2_N PF00176.23 EPS31740.1 - 6.6e-37 127.0 0.0 3.7e-33 114.7 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EPS31740.1 - 1e-07 32.3 0.0 2.6e-07 30.9 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Integrin_alpha PF00357.20 EPS31740.1 - 0.11 12.6 0.0 0.32 11.1 0.0 1.9 1 0 0 1 1 1 0 Integrin alpha cytoplasmic region HMG_box PF00505.19 EPS31741.1 - 2e-21 76.2 0.9 3.4e-21 75.4 0.9 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EPS31741.1 - 2.5e-08 34.4 0.5 5.5e-08 33.3 0.5 1.5 1 0 0 1 1 1 1 HMG-box domain COX4 PF02936.14 EPS31741.1 - 0.086 12.9 0.3 0.17 11.9 0.3 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV MATalpha_HMGbox PF04769.12 EPS31741.1 - 0.19 11.0 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box Ribosomal_S6e PF01092.19 EPS31746.1 - 2.9e-55 185.6 0.0 5.7e-55 184.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e Protocadherin PF08374.11 EPS31746.1 - 0.88 9.5 3.8 1.3 9.0 3.8 1.2 1 0 0 1 1 1 0 Protocadherin Pribosyltran_N PF13793.6 EPS31747.1 - 2.5e-46 156.4 1.1 8e-45 151.5 0.1 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EPS31747.1 - 1.5e-42 145.7 1.9 8.1e-36 123.8 0.8 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EPS31747.1 - 6.9e-19 67.9 0.9 7.2e-18 64.6 0.5 2.2 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EPS31747.1 - 0.00011 21.7 0.2 0.00022 20.7 0.2 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF913 PF06025.12 EPS31748.1 - 1.5e-129 432.2 0.0 1.5e-129 432.2 0.0 6.7 7 1 0 7 7 7 2 Domain of Unknown Function (DUF913) DUF908 PF06012.12 EPS31748.1 - 9e-115 383.9 6.5 9e-115 383.9 6.5 3.8 5 0 0 5 5 5 1 Domain of Unknown Function (DUF908) HECT PF00632.25 EPS31748.1 - 3.5e-96 322.3 0.0 8.6e-96 321.0 0.0 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) UBM PF14377.6 EPS31748.1 - 1.8e-29 100.3 24.7 7.7e-11 41.1 3.2 4.1 3 0 0 3 3 3 3 Ubiquitin binding region HAMP PF00672.25 EPS31748.1 - 0.021 15.2 0.0 0.072 13.5 0.0 2.0 1 0 0 1 1 1 0 HAMP domain UBA PF00627.31 EPS31748.1 - 0.1 12.5 0.2 0.31 11.0 0.2 1.9 1 0 0 1 1 1 0 UBA/TS-N domain DNA_pol3_a_NII PF11490.8 EPS31748.1 - 1.2 9.1 8.9 4.5 7.2 8.9 2.0 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II An_peroxidase PF03098.15 EPS31749.1 - 4.2e-40 137.8 0.1 1.4e-25 89.9 0.0 3.4 1 1 2 3 3 3 3 Animal haem peroxidase p450 PF00067.22 EPS31749.1 - 9e-11 41.2 0.4 9.7e-10 37.8 0.0 2.4 3 0 0 3 3 3 1 Cytochrome P450 Steroid_dh PF02544.16 EPS31752.1 - 9.4e-32 110.1 1.6 1.2e-31 109.7 1.6 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 EPS31752.1 - 1.7e-05 24.5 2.3 2.4e-05 24.0 2.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 EPS31752.1 - 0.0043 17.4 0.2 0.011 16.1 0.2 1.8 1 0 0 1 1 1 1 Phospholipid methyltransferase Glyco_transf_34 PF05637.12 EPS31753.1 - 3.5e-57 193.9 0.0 4.4e-57 193.6 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Ribosomal_L28 PF00830.19 EPS31754.1 - 9.5e-17 61.0 1.4 1.8e-16 60.1 1.4 1.3 1 0 0 1 1 1 1 Ribosomal L28 family TIP49 PF06068.13 EPS31755.1 - 3.4e-167 556.0 0.1 4.1e-167 555.8 0.1 1.0 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EPS31755.1 - 3.3e-22 78.4 0.0 9.5e-22 76.9 0.0 1.8 2 0 0 2 2 1 1 TIP49 AAA-lid domain AAA PF00004.29 EPS31755.1 - 3.3e-11 43.7 0.2 3.8e-07 30.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EPS31755.1 - 3.1e-10 40.0 0.2 8.5e-07 28.8 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EPS31755.1 - 8.2e-06 26.1 0.1 0.042 14.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EPS31755.1 - 0.00013 22.3 0.8 0.064 13.6 0.3 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EPS31755.1 - 0.00014 22.3 0.1 0.0019 18.6 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EPS31755.1 - 0.00075 19.5 0.2 0.19 11.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EPS31755.1 - 0.00084 19.6 0.1 0.002 18.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EPS31755.1 - 0.0012 18.5 0.1 1.1 8.9 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Zeta_toxin PF06414.12 EPS31755.1 - 0.0052 16.1 0.4 0.016 14.5 0.3 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.6 EPS31755.1 - 0.0082 15.7 0.1 0.019 14.6 0.1 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EPS31755.1 - 0.013 14.9 0.1 0.58 9.5 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 EPS31755.1 - 0.043 13.1 0.7 0.15 11.3 0.1 2.0 2 0 0 2 2 2 0 KaiC DnaB_C PF03796.15 EPS31755.1 - 0.05 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_18 PF13238.6 EPS31755.1 - 0.053 14.1 0.1 0.29 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EPS31755.1 - 0.058 13.1 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.9 EPS31755.1 - 0.067 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.6 EPS31755.1 - 0.1 12.3 0.2 1.4 8.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EPS31755.1 - 0.11 12.0 0.1 0.43 10.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region TetR_C_30 PF17939.1 EPS31755.1 - 0.16 12.2 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain V-SNARE PF05008.15 EPS31756.1 - 1.4e-21 76.6 7.7 1.4e-21 76.6 7.7 1.8 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 EPS31756.1 - 1.5e-13 50.8 2.1 1.5e-13 50.8 2.1 2.8 3 1 0 3 3 2 1 Snare region anchored in the vesicle membrane C-terminus DUF3510 PF12022.8 EPS31756.1 - 0.02 15.2 0.9 0.034 14.5 0.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3510) DUF349 PF03993.12 EPS31756.1 - 0.067 13.5 7.1 1.5 9.2 0.2 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) Fusion_gly PF00523.18 EPS31756.1 - 0.14 10.3 3.5 0.37 9.0 0.3 2.2 2 0 0 2 2 2 0 Fusion glycoprotein F0 zf-C4H2 PF10146.9 EPS31756.1 - 0.87 9.9 7.6 3.5 7.9 7.6 2.0 1 1 0 1 1 1 0 Zinc finger-containing protein Exonuc_VII_L PF02601.15 EPS31756.1 - 0.99 8.9 10.5 1.7 8.1 10.5 1.5 1 1 0 1 1 1 0 Exonuclease VII, large subunit TBCA PF02970.16 EPS31756.1 - 1 9.7 8.5 0.45 10.9 3.4 2.3 2 1 0 2 2 2 0 Tubulin binding cofactor A DUF2408 PF10303.9 EPS31756.1 - 1.1 9.9 5.7 0.99 10.0 3.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) FAM184 PF15665.5 EPS31756.1 - 1.2 8.8 11.3 0.53 10.0 6.2 2.2 1 1 2 3 3 3 0 Family with sequence similarity 184, A and B SKA2 PF16740.5 EPS31756.1 - 2.1 8.2 8.6 13 5.7 0.2 3.0 1 1 2 3 3 3 0 Spindle and kinetochore-associated protein 2 End3 PF12761.7 EPS31756.1 - 2.3 8.3 11.1 1.6 8.9 8.7 1.9 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 SNARE PF05739.19 EPS31756.1 - 3.7 7.6 6.2 0.37 10.8 0.6 2.3 3 0 0 3 3 3 0 SNARE domain DUF4083 PF13314.6 EPS31756.1 - 6 6.9 9.9 21 5.1 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Synaptobrevin PF00957.21 EPS31756.1 - 9.7 6.1 9.9 0.3 10.9 0.6 2.9 4 0 0 4 4 4 0 Synaptobrevin DUF2407_C PF13373.6 EPS31757.1 - 3.7e-42 143.8 1.0 4.7e-42 143.5 0.1 1.6 2 0 0 2 2 2 1 DUF2407 C-terminal domain DUF2407 PF10302.9 EPS31757.1 - 3.5e-34 117.5 0.0 6.9e-34 116.5 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 EPS31757.1 - 0.0048 16.6 0.0 0.0099 15.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF5130 PF17174.4 EPS31757.1 - 0.087 13.0 0.1 0.19 11.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5130) Fe-S_biosyn PF01521.20 EPS31759.1 - 1.3e-17 64.0 0.0 1.7e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Med3 PF11593.8 EPS31759.1 - 0.29 10.3 10.7 0.35 10.0 10.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF1741 PF08427.10 EPS31760.1 - 6.8e-93 310.6 0.0 1.1e-92 310.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) MRG PF05712.13 EPS31761.1 - 1.2e-53 181.4 0.5 1.8e-53 180.8 0.5 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 EPS31761.1 - 2e-09 37.2 2.5 3.8e-09 36.3 2.5 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 EPS31761.1 - 0.016 15.1 1.9 0.035 14.0 1.9 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Cnl2_NKP2 PF09447.10 EPS31762.1 - 2e-27 95.1 0.8 5e-27 93.8 0.8 1.7 1 0 0 1 1 1 1 Cnl2/NKP2 family protein DUF1887 PF09002.11 EPS31762.1 - 0.021 13.5 0.8 0.024 13.3 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1887) GlutR_dimer PF00745.20 EPS31762.1 - 0.022 15.2 2.0 0.04 14.4 1.2 2.0 2 0 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain DUF948 PF06103.11 EPS31762.1 - 0.035 14.3 0.1 0.1 12.9 0.0 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CRISPR_Cse1 PF09481.10 EPS31762.1 - 0.042 12.9 0.2 0.049 12.7 0.2 1.1 1 0 0 1 1 1 0 CRISPR-associated protein Cse1 (CRISPR_cse1) Nsp1_C PF05064.13 EPS31762.1 - 0.11 12.3 2.8 0.56 10.0 1.0 2.2 1 1 1 2 2 2 0 Nsp1-like C-terminal region APG6_N PF17675.1 EPS31762.1 - 1.6 9.3 10.2 1.5 9.4 0.1 2.5 2 1 1 3 3 3 0 Apg6 coiled-coil region FUSC PF04632.12 EPS31762.1 - 2.9 6.3 7.3 9.5 4.6 7.5 1.5 1 1 0 1 1 1 0 Fusaric acid resistance protein family Ctf8 PF09696.10 EPS31763.1 - 2e-45 154.6 0.4 1.8e-44 151.6 0.4 1.9 1 1 0 1 1 1 1 Ctf8 Dabb PF07876.12 EPS31764.1 - 6.3e-12 46.0 0.0 6.9e-12 45.8 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain PocR PF10114.9 EPS31764.1 - 0.015 15.1 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Sensory domain found in PocR DUF1687 PF07955.11 EPS31764.1 - 0.032 14.7 0.0 0.041 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1687) RabGAP-TBC PF00566.18 EPS31765.1 - 5.1e-53 179.9 0.2 1.8e-52 178.1 0.2 2.0 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF812 PF05667.11 EPS31765.1 - 0.0039 16.2 12.0 0.0039 16.2 12.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF812) Cnn_1N PF07989.11 EPS31765.1 - 1 9.5 18.9 1.7 8.8 7.0 3.2 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 Z1 PF10593.9 EPS31765.1 - 1.8 8.0 6.9 3.8 7.0 6.9 1.6 1 0 0 1 1 1 0 Z1 domain YabA PF06156.13 EPS31765.1 - 7 7.4 19.6 0.36 11.5 2.8 3.4 2 1 1 3 3 3 0 Initiation control protein YabA DUF1664 PF07889.12 EPS31765.1 - 8.6 6.4 8.9 8 6.5 6.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) KapB PF08810.10 EPS31765.1 - 9.1 6.5 6.4 2.9 8.1 1.7 2.3 1 1 1 2 2 2 0 Kinase associated protein B PPTA PF01239.22 EPS31766.1 - 7e-35 117.8 14.0 4.8e-07 29.3 1.0 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat Caroten_synth PF04240.12 EPS31766.1 - 0.025 14.4 0.1 0.14 12.0 0.0 2.0 1 1 1 2 2 2 0 Carotenoid biosynthesis protein WD40 PF00400.32 EPS31767.1 - 4.6e-08 33.6 3.1 0.094 13.6 0.0 5.9 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS31767.1 - 1.1e-06 28.9 0.0 0.025 14.9 0.0 4.5 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 EPS31768.1 - 5.4e-24 84.6 0.1 1.2e-23 83.5 0.1 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family Na_trans_assoc PF06512.13 EPS31768.1 - 0.0093 16.3 3.8 0.0093 16.3 3.8 2.6 2 0 0 2 2 2 1 Sodium ion transport-associated Bromodomain PF00439.25 EPS31770.1 - 9.1e-39 131.4 0.1 6.2e-19 67.9 0.0 2.8 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 EPS31770.1 - 1.2e-19 70.2 1.4 3.7e-19 68.7 1.4 1.9 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation DUF3573 PF12097.8 EPS31770.1 - 0.08 11.8 4.2 0.14 11.0 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) HAUS4 PF14735.6 EPS31772.1 - 0.0086 15.8 2.9 0.027 14.2 1.6 2.1 2 0 0 2 2 2 1 HAUS augmin-like complex subunit 4 ZapB PF06005.12 EPS31772.1 - 0.049 14.1 8.6 0.48 10.9 1.0 3.3 3 0 0 3 3 3 0 Cell division protein ZapB GA-like PF17573.2 EPS31772.1 - 0.11 12.4 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 GA-like domain PARG_cat PF05028.14 EPS31773.1 - 3e-43 148.4 0.0 5.1e-25 88.5 0.0 2.1 1 1 1 2 2 2 2 Poly (ADP-ribose) glycohydrolase (PARG) AKAP_110 PF05716.13 EPS31773.1 - 0.029 12.6 0.0 0.041 12.1 0.0 1.1 1 0 0 1 1 1 0 A-kinase anchor protein 110 kDa (AKAP 110) zf-CSL PF05207.13 EPS31774.1 - 1e-21 76.4 0.3 1.3e-21 76.1 0.3 1.1 1 0 0 1 1 1 1 CSL zinc finger NAD_binding_8 PF13450.6 EPS31776.1 - 3.1e-12 46.6 0.0 6.7e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EPS31776.1 - 1.5e-09 37.8 0.0 2.3e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EPS31776.1 - 1.9e-07 30.6 0.2 4.7e-07 29.2 0.2 1.6 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EPS31776.1 - 9e-07 28.8 0.0 2.3e-06 27.4 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EPS31776.1 - 1.3e-06 27.4 0.3 4e-06 25.8 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.24 EPS31776.1 - 3e-05 23.5 0.0 4.9e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 EPS31776.1 - 3.3e-05 23.3 0.0 0.00015 21.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPS31776.1 - 0.00023 21.7 0.1 0.00043 20.8 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EPS31776.1 - 0.00037 19.8 0.1 0.00068 19.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 EPS31776.1 - 0.0043 16.2 0.0 0.007 15.5 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 EPS31776.1 - 0.005 15.8 0.1 0.0069 15.3 0.1 1.1 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_3 PF13738.6 EPS31776.1 - 0.012 14.9 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EPS31776.1 - 0.013 14.7 0.1 0.023 13.9 0.1 1.3 1 0 0 1 1 1 0 Thi4 family IlvN PF07991.12 EPS31776.1 - 0.038 13.5 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain ApbA PF02558.16 EPS31776.1 - 0.075 12.7 0.1 0.17 11.5 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.6 EPS31776.1 - 0.14 12.2 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Frataxin_Cyay PF01491.16 EPS31778.1 - 7.7e-34 116.0 0.0 9.6e-34 115.7 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain His_Phos_2 PF00328.22 EPS31779.1 - 1.4e-27 97.1 0.1 1.8e-27 96.7 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Lactamase_B PF00753.27 EPS31781.1 - 1.4e-10 41.5 0.1 1.6e-10 41.3 0.1 1.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EPS31781.1 - 0.00043 19.9 0.1 0.0033 16.9 0.0 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EPS31781.1 - 0.013 15.4 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain MFS_1 PF07690.16 EPS31782.1 - 7.3e-25 87.6 69.1 7.1e-16 58.1 30.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TPP_enzyme_N PF02776.18 EPS31783.1 - 3.2e-56 189.6 0.0 6.8e-56 188.6 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EPS31783.1 - 4.2e-42 143.5 0.1 1.2e-39 135.5 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EPS31783.1 - 1.4e-30 105.8 0.0 2.3e-30 105.1 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain AAL_decarboxy PF03306.13 EPS31784.1 - 8.5e-72 241.0 0.3 9.6e-72 240.9 0.3 1.0 1 0 0 1 1 1 1 Alpha-acetolactate decarboxylase Cellulase PF00150.18 EPS31785.1 - 6.3e-13 48.8 0.0 9.2e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF202 PF02656.15 EPS31786.1 - 3.9e-14 52.8 8.3 1.2e-13 51.3 5.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF5134 PF17197.4 EPS31786.1 - 0.025 14.5 0.1 0.031 14.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5134) CoA_binding_3 PF13727.6 EPS31786.1 - 0.06 13.4 1.4 0.074 13.1 1.4 1.3 1 0 0 1 1 1 0 CoA-binding domain DUF5337 PF17272.2 EPS31786.1 - 0.17 11.7 8.4 0.41 10.5 5.7 2.5 2 1 0 2 2 2 0 Family of unknown function (DUF5337) DUF4131 PF13567.6 EPS31786.1 - 1.6 8.3 6.8 1.8 8.2 4.5 2.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) GMC_oxred_N PF00732.19 EPS31787.1 - 2e-60 204.7 0.0 2.6e-60 204.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EPS31787.1 - 5.7e-32 111.2 0.7 1.3e-31 110.1 0.7 1.7 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.12 EPS31787.1 - 0.0004 19.5 0.1 0.00067 18.8 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.17 EPS31787.1 - 0.0011 18.3 1.3 0.014 14.6 0.1 2.8 3 0 0 3 3 3 1 Thi4 family DAO PF01266.24 EPS31787.1 - 0.004 16.8 2.4 0.013 15.1 1.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EPS31787.1 - 0.014 14.2 0.0 0.088 11.6 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase FAD_binding_2 PF00890.24 EPS31787.1 - 0.018 14.1 0.4 0.079 12.0 0.2 2.0 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.6 EPS31787.1 - 0.023 14.9 0.0 0.061 13.6 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EPS31787.1 - 0.054 12.7 0.0 0.18 11.0 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 EPS31788.1 - 2.9e-17 62.6 38.0 2.9e-17 62.6 38.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 EPS31788.1 - 1.2e-06 28.4 7.7 1.2e-06 28.4 7.7 2.6 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 MKRN1_C PF15815.5 EPS31789.1 - 0.056 13.8 0.3 0.056 13.8 0.3 1.8 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase makorin-1, C-terminal zf-C2H2_3rep PF18868.1 EPS31789.1 - 0.24 12.1 2.3 6 7.6 0.0 2.7 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats BIR PF00653.21 EPS31789.1 - 0.55 10.9 5.0 5.2 7.8 0.1 2.9 2 1 0 2 2 2 0 Inhibitor of Apoptosis domain Methyltransf_PK PF05891.12 EPS31790.1 - 2.9e-68 229.7 0.0 3.4e-68 229.4 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.6 EPS31790.1 - 1.1e-05 25.3 0.0 1.7e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPS31790.1 - 1.2e-05 25.9 0.0 2.3e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS31790.1 - 4.5e-05 24.0 0.0 7.5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CitG PF01874.16 EPS31790.1 - 0.033 13.9 0.0 0.046 13.4 0.0 1.1 1 0 0 1 1 1 0 ATP:dephospho-CoA triphosphoribosyl transferase Methyltransf_12 PF08242.12 EPS31790.1 - 0.08 13.7 0.0 0.18 12.5 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.18 EPS31790.1 - 0.082 12.2 0.1 0.14 11.4 0.1 1.5 1 1 0 1 1 1 0 O-methyltransferase domain GFA PF04828.14 EPS31791.1 - 0.0045 17.3 0.0 0.0058 17.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Zn_ribbon_recom PF13408.6 EPS31791.1 - 0.056 14.0 0.0 0.1 13.1 0.0 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain FAD_binding_4 PF01565.23 EPS31792.1 - 2e-18 66.5 0.7 3.5e-18 65.7 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EPS31792.1 - 3.8e-07 30.1 0.1 8.7e-07 29.0 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like DAO PF01266.24 EPS31793.1 - 4e-36 125.3 1.8 4.5e-36 125.1 1.8 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EPS31793.1 - 0.0002 20.6 0.0 0.00027 20.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EPS31793.1 - 0.00026 20.3 0.0 0.0065 15.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPS31793.1 - 0.0022 18.5 0.1 0.006 17.1 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPS31793.1 - 0.0027 17.9 1.9 0.0055 16.9 0.1 2.4 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EPS31793.1 - 0.011 15.8 0.1 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.17 EPS31793.1 - 0.011 15.0 0.5 0.046 12.9 0.1 2.2 2 0 0 2 2 2 0 Thi4 family Pyr_redox_3 PF13738.6 EPS31793.1 - 0.018 14.3 0.0 0.12 11.6 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EPS31793.1 - 0.036 14.5 0.0 0.095 13.2 0.0 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding ApbA PF02558.16 EPS31793.1 - 0.1 12.2 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.19 EPS31793.1 - 0.13 11.5 0.2 0.29 10.3 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain Ldh_1_N PF00056.23 EPS31793.1 - 0.19 11.8 0.1 16 5.6 0.0 2.3 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain FA_desaturase PF00487.24 EPS31794.1 - 3.4e-26 92.6 25.4 6.8e-26 91.6 25.4 1.4 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 EPS31794.1 - 0.065 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) NIF PF03031.18 EPS31795.1 - 5.3e-58 195.2 0.0 9.8e-58 194.3 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase IF-2B PF01008.17 EPS31796.1 - 7.7e-61 205.8 0.7 5.5e-37 127.5 0.1 2.7 2 1 0 2 2 2 2 Initiation factor 2 subunit family Ribosom_S12_S23 PF00164.25 EPS31797.1 - 2.8e-21 75.2 0.0 4.2e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 DUF5315 PF17242.2 EPS31798.1 - 9.8e-25 86.2 4.2 2.4e-24 84.9 4.2 1.6 1 0 0 1 1 1 1 Disordered region of unknown function (DUF5315) HH_signal PF01085.18 EPS31798.1 - 0.064 12.9 0.3 0.1 12.3 0.3 1.3 1 0 0 1 1 1 0 Hedgehog amino-terminal signalling domain AIM5 PF17050.5 EPS31799.1 - 6.6e-12 46.1 1.5 9.1e-12 45.6 1.5 1.2 1 0 0 1 1 1 1 Altered inheritance of mitochondria 5 Mn_catalase PF05067.12 EPS31799.1 - 0.072 12.1 0.1 0.24 10.4 0.1 1.7 1 1 0 1 1 1 0 Manganese containing catalase Ribosomal_L17 PF01196.19 EPS31800.1 - 3e-29 101.8 0.1 2.2e-27 95.8 0.0 2.4 2 0 0 2 2 2 2 Ribosomal protein L17 SUZ PF12752.7 EPS31801.1 - 5.4e-12 46.3 9.1 5.4e-12 46.3 9.1 5.3 5 1 0 5 5 5 1 SUZ domain R3H PF01424.22 EPS31801.1 - 8.7e-08 32.0 0.0 2.3e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 R3H domain zf-CCHC_3 PF13917.6 EPS31802.1 - 3e-18 65.5 4.2 6.9e-18 64.3 4.2 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 EPS31802.1 - 0.045 13.5 0.5 0.12 12.2 0.5 1.7 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.23 EPS31802.1 - 0.15 12.2 1.3 0.27 11.4 1.3 1.4 1 0 0 1 1 1 0 Zinc knuckle cwf18 PF08315.12 EPS31803.1 - 2.6e-45 154.4 7.9 4e-45 153.8 7.9 1.3 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor SAA PF00277.18 EPS31803.1 - 0.076 13.5 1.0 0.33 11.5 0.0 2.1 2 0 0 2 2 2 0 Serum amyloid A protein PPR_2 PF13041.6 EPS31804.1 - 2e-11 43.9 5.7 8.3e-05 22.7 0.1 5.6 3 2 2 5 5 5 3 PPR repeat family PPR_3 PF13812.6 EPS31804.1 - 6.1e-09 35.8 0.0 0.1 12.7 0.1 3.8 3 0 0 3 3 3 3 Pentatricopeptide repeat domain PPR PF01535.20 EPS31804.1 - 6.7e-05 22.9 0.0 0.2 12.0 0.0 4.1 4 0 0 4 4 4 1 PPR repeat DUF4070 PF13282.6 EPS31804.1 - 0.017 15.3 0.3 0.12 12.5 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4070) PPR_1 PF12854.7 EPS31804.1 - 0.021 14.5 0.4 0.38 10.5 0.0 3.3 5 0 0 5 5 5 0 PPR repeat PPR_long PF17177.4 EPS31804.1 - 0.074 12.4 0.4 7.7 5.8 0.0 2.5 2 0 0 2 2 2 0 Pentacotripeptide-repeat region of PRORP DUF4817 PF16087.5 EPS31804.1 - 0.19 11.6 0.8 0.49 10.2 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain (DUF4817) DUF1242 PF06842.12 EPS31805.1 - 5.8e-18 64.4 0.2 9e-18 63.8 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) TFIID-18kDa PF02269.16 EPS31806.1 - 2.8e-24 85.0 0.0 4.7e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-S PF15630.6 EPS31806.1 - 0.00011 22.4 0.0 0.00021 21.6 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein Histone PF00125.24 EPS31806.1 - 0.00057 20.3 0.0 0.00057 20.3 0.0 2.2 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 EPS31806.1 - 0.0022 18.1 0.0 0.0042 17.2 0.0 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-T_C PF15511.6 EPS31806.1 - 0.0051 16.9 0.1 0.0087 16.2 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 EPS31806.1 - 0.0065 16.4 0.0 0.011 15.7 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.13 EPS31806.1 - 0.0085 16.6 0.0 0.017 15.6 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 EPS31806.1 - 0.011 16.0 3.4 0.012 15.9 0.1 2.4 3 0 0 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EPS31806.1 - 0.015 15.4 0.0 0.02 15.0 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit zf-P11 PF03854.14 EPS31807.1 - 0.21 11.3 3.2 0.37 10.5 3.2 1.3 1 0 0 1 1 1 0 P-11 zinc finger JAB PF01398.21 EPS31808.1 - 5.2e-20 71.6 0.0 9.4e-20 70.8 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EPS31808.1 - 3.7e-19 69.2 0.3 6e-19 68.5 0.3 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function UPF0172 PF03665.13 EPS31808.1 - 0.0012 19.0 0.0 0.0032 17.5 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0172) DUF3232 PF11554.8 EPS31808.1 - 0.11 12.8 0.2 0.21 12.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3232) UTP25 PF06862.12 EPS31809.1 - 4.3e-190 632.5 0.0 5.5e-190 632.1 0.0 1.1 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 EPS31809.1 - 0.075 12.8 0.1 11 5.8 0.0 3.0 3 0 0 3 3 3 0 DEAD/DEAH box helicase Rotamase_2 PF13145.6 EPS31809.1 - 0.29 12.0 4.6 1.1 10.1 3.3 2.5 2 1 0 2 2 2 0 PPIC-type PPIASE domain Glyco_hydro_61 PF03443.14 EPS31810.1 - 2.6e-46 158.1 0.5 4.6e-46 157.3 0.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 EamA PF00892.20 EPS31811.1 - 2.4e-20 73.1 32.1 9.1e-14 51.8 11.0 2.5 2 1 0 2 2 2 2 EamA-like transporter family DMT_YdcZ PF04657.13 EPS31811.1 - 5.3 7.3 22.9 1.6 9.0 7.0 3.2 3 0 0 3 3 3 0 Putative inner membrane exporter, YdcZ Glyco_hydro_127 PF07944.12 EPS31812.1 - 1.4e-140 469.3 0.2 1.6e-140 469.1 0.2 1.0 1 0 0 1 1 1 1 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_88 PF07470.13 EPS31812.1 - 0.0026 16.9 0.5 0.74 8.8 0.0 2.6 1 1 3 4 4 4 4 Glycosyl Hydrolase Family 88 CTP_transf_like PF01467.26 EPS31813.1 - 5.4e-30 104.5 0.0 8.9e-30 103.8 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like FAD_binding_4 PF01565.23 EPS31814.1 - 1.8e-13 50.4 3.9 5.3e-13 48.9 3.4 2.1 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.12 EPS31814.1 - 2.7e-12 46.6 0.1 5.4e-12 45.6 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Glyco_hydro_28 PF00295.17 EPS31814.1 - 0.02 14.0 2.9 0.033 13.3 2.9 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 28 PP2C PF00481.21 EPS31816.1 - 3.4e-82 275.9 0.1 7.3e-82 274.9 0.0 1.5 2 0 0 2 2 2 1 Protein phosphatase 2C S_100 PF01023.19 EPS31817.1 - 0.094 12.4 0.0 3.9 7.3 0.0 2.2 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain MOZART1 PF12554.8 EPS31818.1 - 7e-24 83.4 1.8 8.7e-24 83.1 1.8 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated DUF1844 PF08899.11 EPS31818.1 - 0.017 15.4 0.1 0.031 14.6 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1844) SRP54_N PF02881.19 EPS31818.1 - 0.027 14.7 0.4 0.044 14.0 0.4 1.4 1 1 0 1 1 1 0 SRP54-type protein, helical bundle domain WXG100 PF06013.12 EPS31818.1 - 0.064 13.5 0.1 5 7.4 0.1 2.1 2 0 0 2 2 2 0 Proteins of 100 residues with WXG CUE PF02845.16 EPS31819.1 - 3.5e-13 49.0 0.0 5.4e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 CUE domain UBA_4 PF14555.6 EPS31819.1 - 0.013 15.3 0.2 0.023 14.5 0.2 1.4 1 0 0 1 1 1 0 UBA-like domain AFOR_C PF01314.18 EPS31819.1 - 0.047 12.7 0.1 0.075 12.0 0.1 1.2 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 HA2 PF04408.23 EPS31820.1 - 5.9e-17 61.9 0.1 1.2e-16 61.0 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EPS31820.1 - 1.2e-12 48.0 0.0 2.7e-12 46.9 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EPS31820.1 - 3.7e-12 46.6 0.0 8.3e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EPS31820.1 - 2.3e-05 24.2 0.1 4.5e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EPS31820.1 - 5.6e-05 23.4 0.1 0.00019 21.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EPS31820.1 - 8.4e-05 22.4 0.1 0.00017 21.4 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EPS31820.1 - 0.00091 19.6 0.1 0.0024 18.2 0.1 1.7 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 EPS31820.1 - 0.0054 16.3 0.1 0.17 11.5 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 EPS31820.1 - 0.027 13.5 0.0 0.059 12.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.6 EPS31820.1 - 0.045 13.8 0.3 2.8 8.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 EPS31820.1 - 0.14 11.4 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PITH PF06201.13 EPS31821.1 - 5.8e-44 150.0 0.0 6.9e-44 149.7 0.0 1.1 1 0 0 1 1 1 1 PITH domain Snf7 PF03357.21 EPS31822.1 - 7.3e-35 120.1 7.0 9.7e-35 119.7 7.0 1.1 1 0 0 1 1 1 1 Snf7 dUTPase PF00692.19 EPS31822.1 - 0.075 12.7 0.1 0.2 11.3 0.1 1.7 1 1 0 1 1 1 0 dUTPase AAA PF00004.29 EPS31823.1 - 1.5e-88 294.0 0.0 1.3e-43 148.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EPS31823.1 - 4.9e-22 77.5 1.5 1e-09 38.0 0.2 2.9 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 EPS31823.1 - 4.4e-14 52.5 0.0 1.2e-06 28.3 0.0 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EPS31823.1 - 2.2e-13 50.9 1.3 0.00014 22.2 0.2 4.5 2 2 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 EPS31823.1 - 4.8e-12 46.3 0.5 0.013 15.8 0.0 5.1 2 2 3 5 5 5 2 AAA domain AAA_5 PF07728.14 EPS31823.1 - 4.9e-11 42.8 0.2 0.00053 20.0 0.1 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EPS31823.1 - 1.2e-10 41.8 0.0 0.00011 22.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EPS31823.1 - 3.6e-10 40.2 0.0 0.00011 22.4 0.0 2.8 3 0 0 3 3 2 2 AAA domain TIP49 PF06068.13 EPS31823.1 - 1.2e-08 34.6 0.0 0.00015 21.1 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain RNA_helicase PF00910.22 EPS31823.1 - 1.3e-07 32.0 0.0 0.0068 16.8 0.0 2.6 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 EPS31823.1 - 3.1e-07 30.0 0.3 0.022 14.1 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EPS31823.1 - 3.5e-07 30.3 0.0 0.0096 16.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EPS31823.1 - 5.9e-07 30.1 0.0 0.013 16.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 EPS31823.1 - 6.5e-07 29.7 0.0 0.0079 16.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 EPS31823.1 - 8.9e-07 28.8 0.2 0.048 13.4 0.0 2.7 2 1 0 2 2 2 2 IstB-like ATP binding protein Zeta_toxin PF06414.12 EPS31823.1 - 2.3e-06 27.0 0.0 0.061 12.6 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_3 PF07726.11 EPS31823.1 - 2.3e-06 27.5 0.0 0.0085 15.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 EPS31823.1 - 8.2e-06 25.8 0.0 0.048 13.7 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EPS31823.1 - 1.1e-05 25.4 0.3 0.14 12.1 0.0 3.4 4 0 0 4 4 3 2 NACHT domain AAA_25 PF13481.6 EPS31823.1 - 1.3e-05 24.9 0.8 0.92 9.1 0.0 4.0 2 1 0 3 3 3 2 AAA domain Rad17 PF03215.15 EPS31823.1 - 1.6e-05 24.9 0.0 0.095 12.6 0.0 2.7 2 1 0 2 2 2 2 Rad17 P-loop domain AAA_7 PF12775.7 EPS31823.1 - 1.7e-05 24.4 0.0 0.073 12.6 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region ATPase PF06745.13 EPS31823.1 - 2e-05 24.0 0.0 0.34 10.2 0.0 3.1 2 1 0 2 2 2 2 KaiC Cytidylate_kin2 PF13189.6 EPS31823.1 - 2.1e-05 24.7 0.0 0.0029 17.8 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family ABC_tran PF00005.27 EPS31823.1 - 7.9e-05 23.2 0.0 0.49 10.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter Sigma54_activat PF00158.26 EPS31823.1 - 8.3e-05 22.4 0.0 0.24 11.1 0.0 2.9 3 0 0 3 3 2 2 Sigma-54 interaction domain AAA_17 PF13207.6 EPS31823.1 - 0.00016 22.1 0.1 0.34 11.3 0.1 3.1 2 1 0 2 2 2 1 AAA domain PhoH PF02562.16 EPS31823.1 - 0.00025 20.6 0.0 0.36 10.2 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein NB-ARC PF00931.22 EPS31823.1 - 0.00025 20.3 0.0 1 8.5 0.0 3.1 3 0 0 3 3 3 2 NB-ARC domain TniB PF05621.11 EPS31823.1 - 0.00027 20.4 0.0 0.23 10.8 0.0 3.4 4 0 0 4 4 3 1 Bacterial TniB protein AFG1_ATPase PF03969.16 EPS31823.1 - 0.00036 19.5 0.1 0.1 11.5 0.0 2.7 2 1 0 2 2 2 1 AFG1-like ATPase SKI PF01202.22 EPS31823.1 - 0.00079 19.6 0.0 0.85 9.7 0.0 2.8 2 0 0 2 2 2 1 Shikimate kinase AAA_11 PF13086.6 EPS31823.1 - 0.00089 19.1 0.0 1.3 8.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 EPS31823.1 - 0.00093 19.0 0.0 0.98 9.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.17 EPS31823.1 - 0.0012 18.0 0.0 1.5 7.8 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.6 EPS31823.1 - 0.0013 18.9 0.0 2.6 8.2 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain ATPase_2 PF01637.18 EPS31823.1 - 0.003 17.5 0.0 1.9 8.3 0.0 3.2 2 2 1 3 3 3 1 ATPase domain predominantly from Archaea DUF815 PF05673.13 EPS31823.1 - 0.0031 16.7 0.0 0.067 12.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Viral_helicase1 PF01443.18 EPS31823.1 - 0.0041 16.9 0.0 2.3 7.9 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 EPS31823.1 - 0.014 15.8 1.6 4.6 7.6 0.2 3.0 2 1 0 2 2 2 0 AAA domain CPT PF07931.12 EPS31823.1 - 0.015 15.1 0.0 0.39 10.6 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein ResIII PF04851.15 EPS31823.1 - 0.026 14.5 0.0 13 5.7 0.0 2.8 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit IPT PF01745.16 EPS31823.1 - 0.031 13.7 0.0 3.5 6.9 0.0 2.5 2 0 0 2 2 2 0 Isopentenyl transferase DUF2075 PF09848.9 EPS31823.1 - 0.05 12.8 0.0 3.7 6.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.15 EPS31823.1 - 0.051 13.5 0.0 6.8 6.6 0.0 2.8 2 1 1 3 3 2 0 NTPase AAA_30 PF13604.6 EPS31823.1 - 0.085 12.6 0.0 16 5.2 0.0 2.6 3 0 0 3 3 2 0 AAA domain Glyco_hydro_76 PF03663.14 EPS31824.1 - 3.6e-137 457.8 14.8 4.6e-137 457.4 14.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_127 PF07944.12 EPS31824.1 - 0.031 12.8 0.1 3.4 6.0 0.0 2.6 1 1 2 3 3 3 0 Beta-L-arabinofuranosidase, GH127 Glyco_hydro_88 PF07470.13 EPS31824.1 - 0.033 13.3 12.2 0.084 11.9 2.2 3.1 2 1 0 3 3 3 0 Glycosyl Hydrolase Family 88 BOP1NT PF08145.12 EPS31825.1 - 8.7e-105 350.3 5.8 1.3e-104 349.7 5.8 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 EPS31825.1 - 1.3e-23 82.8 5.9 8.9e-10 39.0 0.2 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS31825.1 - 2e-06 28.0 0.0 0.0056 17.0 0.0 3.7 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain ORF_2_N PF18492.1 EPS31825.1 - 0.059 13.6 0.3 0.9 9.8 0.0 2.3 2 0 0 2 2 2 0 Open reading frame 2 N-terminal domain Zn_clus PF00172.18 EPS31826.1 - 6.6e-08 32.5 7.0 1.9e-07 31.1 7.0 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L37ae PF01780.19 EPS31826.1 - 0.0092 16.0 2.2 3.4 7.8 0.6 2.3 2 0 0 2 2 2 2 Ribosomal L37ae protein family INO80_Ies4 PF08193.11 EPS31826.1 - 0.034 14.1 0.2 0.079 12.9 0.2 1.6 1 0 0 1 1 1 0 INO80 complex subunit Ies4 Rep_fac-A_C PF08646.10 EPS31826.1 - 0.94 9.2 6.4 7.3 6.3 0.0 2.2 2 0 0 2 2 2 0 Replication factor-A C terminal domain Leo1 PF04004.13 EPS31827.1 - 9.6e-28 97.1 0.1 3.9e-27 95.1 0.1 1.9 1 1 0 1 1 1 1 Leo1-like protein Bac_luciferase PF00296.20 EPS31827.1 - 0.15 11.4 6.2 0.32 10.4 6.2 1.6 1 1 0 1 1 1 0 Luciferase-like monooxygenase Mob1_phocein PF03637.17 EPS31828.1 - 4.4e-50 170.0 0.4 4.2e-49 166.8 0.4 2.0 1 1 0 1 1 1 1 Mob1/phocein family GCD14_N PF14801.6 EPS31829.1 - 0.038 13.8 0.0 0.072 12.9 0.0 1.4 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N-term B2 PF11473.8 EPS31830.1 - 0.091 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA binding protein B2 PhoD PF09423.10 EPS31831.1 - 1.2e-08 34.4 2.1 0.00023 20.3 0.5 2.8 2 1 0 2 2 2 2 PhoD-like phosphatase AA_permease_2 PF13520.6 EPS31832.1 - 3.7e-40 138.0 53.1 4.8e-40 137.7 53.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPS31832.1 - 1.5e-24 86.4 48.0 2e-24 86.0 48.0 1.0 1 0 0 1 1 1 1 Amino acid permease PetN PF03742.14 EPS31832.1 - 0.66 9.9 9.4 5.5 7.0 0.4 4.1 3 0 0 3 3 3 0 PetN DUF3336 PF11815.8 EPS31833.1 - 4.4e-37 126.9 0.3 1.1e-35 122.4 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EPS31833.1 - 6.8e-12 46.0 2.1 1e-11 45.4 0.1 2.2 3 0 0 3 3 3 1 Patatin-like phospholipase TAFH PF07531.14 EPS31833.1 - 0.092 12.9 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 NHR1 homology to TAF Sm_multidrug_ex PF06695.11 EPS31833.1 - 0.14 12.8 1.1 0.27 11.9 0.2 2.0 3 0 0 3 3 3 0 Putative small multi-drug export protein Ribosomal_L6 PF00347.23 EPS31834.1 - 6.9e-23 81.1 3.9 5.3e-11 43.0 1.7 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Glutaredoxin PF00462.24 EPS31835.1 - 6.1e-13 48.8 0.0 1.2e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin HupH_C PF04809.13 EPS31835.1 - 0.05 13.3 0.0 0.78 9.5 0.0 2.2 1 1 1 2 2 2 0 HupH hydrogenase expression protein, C-terminal conserved region Abhydrolase_1 PF00561.20 EPS31836.1 - 2.3e-08 34.0 0.0 8e-08 32.2 0.0 2.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EPS31836.1 - 5.2e-07 29.2 0.0 2.7e-05 23.5 0.0 2.9 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Tmemb_cc2 PF10267.9 EPS31836.1 - 1.1 8.4 4.4 2.1 7.4 4.4 1.4 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Gryzun PF07919.12 EPS31837.1 - 1.6e-240 799.9 0.0 1.9e-240 799.7 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.8 EPS31837.1 - 1.9e-105 352.1 0.5 2.4e-95 319.1 0.5 2.4 2 0 0 2 2 2 2 Foie gras liver health family 1 Gryzun-like PF12742.7 EPS31837.1 - 0.011 15.8 0.0 0.022 14.8 0.0 1.5 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking Reprolysin_4 PF13583.6 EPS31837.1 - 0.072 12.7 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like RXT2_N PF08595.11 EPS31838.1 - 4e-42 143.9 0.1 4e-42 143.9 0.1 3.2 2 1 1 3 3 3 1 RXT2-like, N-terminal SH3_3 PF08239.11 EPS31839.1 - 0.00016 21.9 0.1 0.00038 20.7 0.1 1.7 1 1 0 1 1 1 1 Bacterial SH3 domain PEMT PF04191.13 EPS31840.1 - 1.2e-33 115.6 1.6 1.2e-33 115.6 1.6 1.6 2 0 0 2 2 2 1 Phospholipid methyltransferase YrhK PF14145.6 EPS31840.1 - 0.14 12.0 6.8 0.12 12.3 3.8 2.5 2 1 0 2 2 2 0 YrhK-like protein PXA PF02194.15 EPS31841.1 - 1.9e-49 168.1 1.1 7.6e-49 166.1 0.2 2.5 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.12 EPS31841.1 - 4.8e-24 85.1 0.1 3.1e-23 82.5 0.0 2.5 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 EPS31841.1 - 1.6e-21 76.4 0.2 3.8e-21 75.2 0.2 1.7 1 0 0 1 1 1 1 PX domain RGS PF00615.19 EPS31841.1 - 2.9e-09 37.2 0.1 7.5e-09 35.9 0.1 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF3759 PF12585.8 EPS31844.1 - 3.5e-37 126.3 2.6 4.1e-37 126.1 2.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Stm1_N PF09598.10 EPS31845.1 - 0.034 15.0 0.3 0.097 13.5 0.3 1.9 1 1 0 1 1 1 0 Stm1 DUF3475 PF11961.8 EPS31845.1 - 0.16 12.0 0.3 0.4 10.8 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3475) WD40 PF00400.32 EPS31846.1 - 8.4e-19 67.6 4.1 0.00067 20.4 0.2 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS31846.1 - 1.5e-08 34.8 0.0 0.0018 18.5 0.0 5.3 1 1 5 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EPS31846.1 - 0.00033 20.1 0.0 0.0006 19.2 0.0 1.4 1 0 0 1 1 1 1 WD40-like domain Ge1_WD40 PF16529.5 EPS31846.1 - 0.0069 15.4 0.1 0.045 12.7 0.0 2.3 2 2 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein FliC_SP PF12613.8 EPS31846.1 - 0.018 15.5 3.4 4.2 7.9 0.1 2.5 2 0 0 2 2 2 0 Flagellin structural protein tRNA-synt_1g PF09334.11 EPS31847.1 - 1.3e-149 498.3 0.0 1.6e-149 498.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EPS31847.1 - 4.5e-08 31.8 0.0 3.1e-05 22.4 0.0 3.1 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EPS31847.1 - 0.0058 16.6 0.8 0.0089 16.0 0.0 1.7 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA Yae1_N PF09811.9 EPS31848.1 - 1e-07 31.5 2.2 1.5e-07 30.9 2.2 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Fib_alpha PF08702.10 EPS31848.1 - 0.075 13.2 0.0 0.098 12.8 0.0 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family UPF0160 PF03690.13 EPS31849.1 - 1.1e-125 419.5 0.0 1.2e-125 419.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) ICE2 PF08426.10 EPS31850.1 - 1e-153 512.3 10.5 1.2e-153 512.1 10.5 1.0 1 0 0 1 1 1 1 ICE2 MHYT PF03707.16 EPS31850.1 - 1.1 9.5 0.0 1.1 9.5 0.0 3.8 4 0 0 4 4 4 0 Bacterial signalling protein N terminal repeat Endosulfine PF04667.17 EPS31852.1 - 1.2e-28 99.1 0.1 2e-28 98.3 0.1 1.4 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region RNA_Me_trans PF04252.13 EPS31853.1 - 1.4e-82 276.1 0.0 1.6e-82 276.0 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Peptidase_S10 PF00450.22 EPS31854.1 - 9.9e-114 381.0 0.0 1.3e-113 380.6 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Lipase_3 PF01764.25 EPS31855.1 - 4.8e-37 127.0 0.2 1.3e-36 125.6 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) Lipase3_N PF03893.16 EPS31855.1 - 3.9e-05 23.6 0.3 7.8e-05 22.6 0.3 1.5 1 0 0 1 1 1 1 Lipase 3 N-terminal region Hydrolase_4 PF12146.8 EPS31855.1 - 8.2e-05 22.0 0.0 0.00013 21.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EPS31855.1 - 0.00067 20.3 0.1 0.0009 19.9 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 EPS31855.1 - 0.00082 19.1 0.1 0.0013 18.4 0.1 1.4 1 0 0 1 1 1 1 Putative esterase DUF2974 PF11187.8 EPS31855.1 - 0.0045 16.6 1.9 0.086 12.4 0.3 2.9 1 1 1 2 2 2 1 Protein of unknown function (DUF2974) Thioesterase PF00975.20 EPS31855.1 - 0.0076 16.4 0.1 0.014 15.5 0.1 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.20 EPS31855.1 - 0.012 15.2 0.1 0.018 14.7 0.1 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 EPS31855.1 - 0.064 13.0 0.0 0.098 12.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Phosphoesterase PF04185.14 EPS31856.1 - 3.1e-23 82.5 8.6 4.2e-23 82.1 7.3 1.8 1 1 1 2 2 2 1 Phosphoesterase family WD40 PF00400.32 EPS31857.1 - 8.3e-29 99.3 16.2 8.8e-06 26.4 0.0 8.2 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS31857.1 - 7.9e-11 42.1 1.5 0.049 13.9 0.0 4.9 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain NRN1 PF15056.6 EPS31857.1 - 0.003 17.6 0.9 0.0092 16.0 0.1 2.1 2 0 0 2 2 2 1 Neuritin protein family Pox_Ag35 PF03286.14 EPS31858.1 - 0.014 15.2 10.3 0.016 15.0 10.3 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RNA_pol_3_Rpc31 PF11705.8 EPS31858.1 - 0.015 15.5 10.5 0.018 15.3 10.5 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 SWIRM-assoc_2 PF16496.5 EPS31858.1 - 0.031 13.1 7.2 0.035 13.0 7.2 1.0 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Afi1 PF07792.12 EPS31858.1 - 0.051 14.1 2.2 0.065 13.7 2.2 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Myc_N PF01056.18 EPS31858.1 - 0.056 13.3 6.6 0.062 13.2 6.6 1.1 1 0 0 1 1 1 0 Myc amino-terminal region TRAP_alpha PF03896.16 EPS31858.1 - 0.061 12.5 1.8 0.065 12.4 1.8 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Paf1 PF03985.13 EPS31858.1 - 0.076 12.0 11.2 0.088 11.8 11.2 1.1 1 0 0 1 1 1 0 Paf1 Prothymosin PF03247.14 EPS31858.1 - 0.086 13.3 21.0 0.12 12.9 21.0 1.1 1 0 0 1 1 1 0 Prothymosin/parathymosin family DUF4746 PF15928.5 EPS31858.1 - 0.17 11.3 12.4 0.2 11.0 12.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF5427 PF10310.9 EPS31858.1 - 0.19 10.6 10.1 0.2 10.6 10.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5427) TLP-20 PF06088.11 EPS31858.1 - 0.24 11.3 2.7 0.27 11.1 2.7 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) FAM176 PF14851.6 EPS31858.1 - 0.25 11.0 8.4 0.28 10.8 8.4 1.2 1 0 0 1 1 1 0 FAM176 family NPR3 PF03666.13 EPS31858.1 - 0.38 9.5 5.9 0.42 9.4 5.9 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Nucleo_P87 PF07267.11 EPS31858.1 - 0.67 8.7 4.2 0.72 8.6 4.2 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 V_ATPase_I PF01496.19 EPS31858.1 - 1.2 7.0 4.6 1.3 6.9 4.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NOA36 PF06524.12 EPS31858.1 - 1.5 8.1 7.1 1.6 8.0 7.1 1.1 1 0 0 1 1 1 0 NOA36 protein DUF913 PF06025.12 EPS31858.1 - 2.3 7.1 4.8 2.6 6.9 4.8 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 EPS31858.1 - 3.4 7.4 12.5 3.7 7.3 12.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Connexin PF00029.19 EPS31858.1 - 5.3 6.7 4.6 6.6 6.4 4.6 1.3 1 0 0 1 1 1 0 Connexin eIF3_subunit PF08597.10 EPS31858.1 - 6.9 6.5 22.6 8.5 6.2 22.6 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit PBP1_TM PF14812.6 EPS31858.1 - 9 6.7 10.1 17 5.9 10.1 1.6 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PBP_sp32 PF07222.12 EPS31858.1 - 9.8 5.6 12.6 11 5.4 12.6 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Tcp11 PF05794.13 EPS31859.1 - 2.3e-113 379.6 0.1 2.3e-113 379.6 0.1 2.7 3 0 0 3 3 3 1 T-complex protein 11 HTH_13 PF11972.8 EPS31859.1 - 0.11 12.6 0.0 0.44 10.7 0.0 2.1 1 0 0 1 1 1 0 HTH DNA binding domain zinc_ribbon_6 PF14599.6 EPS31860.1 - 4.2e-25 87.5 0.6 4.2e-25 87.5 0.6 3.7 4 0 0 4 4 4 1 Zinc-ribbon zf-CHY PF05495.12 EPS31860.1 - 3.9e-19 68.9 22.2 3.9e-19 68.9 22.2 3.6 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 EPS31860.1 - 2.3e-08 34.2 8.7 2.3e-08 34.2 8.7 5.2 3 2 2 5 5 5 1 Ring finger domain zf-RING_UBOX PF13445.6 EPS31860.1 - 1.3e-06 28.3 5.5 1.3e-06 28.3 5.5 3.7 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EPS31860.1 - 4.2e-05 23.3 6.7 4.2e-05 23.3 6.7 4.7 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EPS31860.1 - 0.0011 19.0 7.0 0.0011 19.0 7.0 4.8 4 1 1 5 5 5 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EPS31860.1 - 0.016 15.0 8.8 0.016 15.0 8.8 5.3 4 1 1 5 5 5 0 Prokaryotic RING finger family 4 DUF1180 PF06679.12 EPS31860.1 - 2.1 8.8 5.1 0.62 10.5 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) Complex1_LYR PF05347.15 EPS31861.1 - 0.0068 16.4 0.2 0.016 15.2 0.2 1.7 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EPS31861.1 - 0.02 15.7 0.2 0.068 13.9 0.2 1.9 1 1 0 1 1 1 0 Complex1_LYR-like DUF2293 PF10056.9 EPS31862.1 - 3.2e-30 104.2 0.3 7.9e-30 102.9 0.3 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) HMA PF00403.26 EPS31863.1 - 1.1e-15 57.8 0.3 1.3e-15 57.6 0.3 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Fer2_BFD PF04324.15 EPS31863.1 - 0.028 14.8 0.2 0.13 12.6 0.1 2.0 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain Rrn6 PF10214.9 EPS31864.1 - 2.2e-235 784.1 0.1 2.7e-235 783.8 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Spindle_Spc25 PF08234.12 EPS31865.1 - 1.2e-21 76.7 0.0 3e-21 75.4 0.0 1.7 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Filament PF00038.21 EPS31865.1 - 0.06 12.9 19.2 0.2 11.2 19.2 1.8 1 1 0 1 1 1 0 Intermediate filament protein Hom_end_hint PF05203.16 EPS31865.1 - 0.12 12.3 0.9 0.14 12.1 0.9 1.2 1 0 0 1 1 1 0 Hom_end-associated Hint WD40 PF00400.32 EPS31866.1 - 4e-22 78.1 14.8 1.2e-07 32.3 0.4 6.4 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS31866.1 - 7.1e-13 48.7 1.0 0.0047 17.2 1.1 4.1 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EPS31866.1 - 7.4e-05 21.6 1.3 0.0011 17.8 0.2 2.5 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 EPS31866.1 - 0.00086 17.9 0.1 0.42 9.1 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain Hira PF07569.11 EPS31866.1 - 0.0012 18.7 0.4 0.56 9.9 0.0 2.7 2 1 1 3 3 3 2 TUP1-like enhancer of split Lactonase PF10282.9 EPS31866.1 - 0.0017 17.7 0.0 1.3 8.2 0.0 2.4 1 1 1 2 2 2 2 Lactonase, 7-bladed beta-propeller Coatomer_WDAD PF04053.14 EPS31866.1 - 0.11 11.6 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region PD40 PF07676.12 EPS31866.1 - 0.35 10.9 1.3 3.1 7.9 0.0 3.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Ribosomal_L32p PF01783.23 EPS31867.1 - 1.3e-14 54.2 7.2 1.5e-14 54.0 7.2 1.1 1 0 0 1 1 1 1 Ribosomal L32p protein family zf-ribbon_3 PF13248.6 EPS31867.1 - 0.0086 15.5 2.2 0.012 15.0 2.2 1.3 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 EPS31867.1 - 0.074 13.1 2.0 0.59 10.2 2.1 1.8 1 1 1 2 2 2 0 Double zinc ribbon Zn-ribbon_8 PF09723.10 EPS31867.1 - 2.2 8.5 5.2 4.4 7.5 0.5 2.2 1 1 1 2 2 2 0 Zinc ribbon domain Septin PF00735.18 EPS31868.1 - 3.4e-113 377.6 0.7 4e-113 377.4 0.7 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EPS31868.1 - 9.6e-08 32.1 0.0 1.9e-07 31.2 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EPS31868.1 - 9.8e-06 25.0 0.0 1.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 EPS31868.1 - 0.00011 21.8 0.9 0.021 14.4 0.1 2.4 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EPS31868.1 - 0.00012 22.0 0.6 0.00086 19.2 0.1 2.2 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 EPS31868.1 - 0.00056 20.0 0.4 1.6 8.8 0.0 2.6 1 1 1 2 2 2 2 Dynamin family AAA_7 PF12775.7 EPS31868.1 - 0.0011 18.5 0.1 0.0065 16.0 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_16 PF13191.6 EPS31868.1 - 0.0015 18.9 0.0 0.0048 17.3 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.22 EPS31868.1 - 0.0051 16.0 0.1 0.0091 15.2 0.1 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.6 EPS31868.1 - 0.013 15.8 0.0 0.034 14.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EPS31868.1 - 0.013 16.0 0.5 0.032 14.7 0.2 1.8 1 1 0 1 1 1 0 ABC transporter Gtr1_RagA PF04670.12 EPS31868.1 - 0.021 14.2 0.1 0.42 9.9 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region G-alpha PF00503.20 EPS31868.1 - 0.032 13.4 0.5 0.29 10.3 0.1 1.8 1 1 1 2 2 2 0 G-protein alpha subunit FtsK_SpoIIIE PF01580.18 EPS31868.1 - 0.037 13.4 0.0 0.071 12.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Roc PF08477.13 EPS31868.1 - 0.04 14.1 0.0 0.08 13.2 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 EPS31868.1 - 0.13 12.8 0.0 0.24 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EPS31868.1 - 0.14 11.9 0.0 8.9 6.0 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Guanylate_kin PF00625.21 EPS31869.1 - 2.7e-63 213.0 0.0 3.2e-63 212.7 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 EPS31869.1 - 3e-08 34.2 0.4 9.4e-08 32.6 0.4 1.7 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 EPS31869.1 - 3.2e-05 24.4 0.0 4.3e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_18 PF13238.6 EPS31869.1 - 4e-05 24.2 0.8 0.00018 22.0 0.3 2.3 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 EPS31869.1 - 5.1e-05 23.6 0.0 0.00061 20.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 EPS31869.1 - 0.0001 22.3 0.0 0.00013 22.0 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_28 PF13521.6 EPS31869.1 - 0.00019 21.7 0.2 0.0013 19.0 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EPS31869.1 - 0.00021 21.5 0.2 0.0018 18.4 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EPS31869.1 - 0.0006 19.8 0.0 0.0013 18.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 EPS31869.1 - 0.00061 19.8 0.1 0.0012 18.9 0.1 1.8 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea MMR_HSR1 PF01926.23 EPS31869.1 - 0.00099 19.2 0.0 0.0024 17.9 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 EPS31869.1 - 0.001 19.4 0.0 0.0019 18.5 0.0 1.7 1 1 0 1 1 1 1 RNA helicase NACHT PF05729.12 EPS31869.1 - 0.0017 18.3 0.0 0.0037 17.2 0.0 1.5 1 0 0 1 1 1 1 NACHT domain RsgA_GTPase PF03193.16 EPS31869.1 - 0.0028 17.6 0.0 0.0052 16.7 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_24 PF13479.6 EPS31869.1 - 0.0034 17.1 0.0 0.29 10.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 EPS31869.1 - 0.0047 16.7 0.0 0.0071 16.1 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA PF00004.29 EPS31869.1 - 0.0089 16.5 0.1 0.028 14.9 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 EPS31869.1 - 0.011 15.0 0.0 0.42 9.8 0.0 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.6 EPS31869.1 - 0.012 16.1 0.1 0.37 11.2 0.0 2.4 2 1 0 2 2 2 0 AAA domain dNK PF01712.19 EPS31869.1 - 0.016 15.1 0.3 0.35 10.7 0.0 2.6 2 1 1 3 3 3 0 Deoxynucleoside kinase AAA_29 PF13555.6 EPS31869.1 - 0.019 14.7 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 EPS31869.1 - 0.02 14.4 0.0 0.04 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 EPS31869.1 - 0.02 15.4 0.1 0.099 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EPS31869.1 - 0.021 14.9 0.3 0.12 12.4 0.0 2.2 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 EPS31869.1 - 0.021 14.8 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 NTPase Adeno_IVa2 PF02456.15 EPS31869.1 - 0.039 12.8 0.0 0.06 12.1 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein cobW PF02492.19 EPS31869.1 - 0.045 13.3 0.0 0.24 11.0 0.0 1.9 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 EPS31869.1 - 0.059 12.5 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.6 EPS31869.1 - 0.075 12.7 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF3987 PF13148.6 EPS31869.1 - 0.15 11.1 0.5 0.32 10.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) T2SSE PF00437.20 EPS31869.1 - 0.18 10.9 0.0 0.46 9.5 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein GRAB PF10375.9 EPS31870.1 - 3.3e-09 36.3 0.1 9.1e-09 34.9 0.1 1.8 1 0 0 1 1 1 1 GRIP-related Arf-binding domain SIKE PF05769.11 EPS31870.1 - 0.00046 20.2 15.0 0.00046 20.2 15.0 2.8 1 1 0 2 2 1 1 SIKE family Spc7 PF08317.11 EPS31870.1 - 0.0022 16.9 54.2 0.0089 14.9 29.8 2.6 1 1 1 2 2 2 2 Spc7 kinetochore protein Lectin_N PF03954.14 EPS31870.1 - 0.013 15.2 5.2 0.013 15.2 5.2 3.8 1 1 1 2 2 1 0 Hepatic lectin, N-terminal domain Baculo_PEP_C PF04513.12 EPS31870.1 - 0.043 13.9 15.6 0.25 11.4 1.4 3.2 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Golgin_A5 PF09787.9 EPS31870.1 - 0.16 11.4 58.9 0.034 13.6 20.1 3.4 1 1 2 3 3 3 0 Golgin subfamily A member 5 DUF1664 PF07889.12 EPS31870.1 - 0.2 11.7 29.8 0.46 10.5 6.7 4.2 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) FUSC PF04632.12 EPS31870.1 - 0.53 8.7 26.9 0.12 10.9 9.4 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein family HALZ PF02183.18 EPS31870.1 - 0.54 10.5 0.0 0.54 10.5 0.0 4.9 5 1 1 6 6 5 0 Homeobox associated leucine zipper FlaC_arch PF05377.11 EPS31870.1 - 0.89 10.0 26.2 1.9 8.9 2.4 6.3 4 2 2 6 6 6 0 Flagella accessory protein C (FlaC) TMF_TATA_bd PF12325.8 EPS31870.1 - 1 9.6 52.8 1.5 9.1 5.7 4.7 1 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding CdvA PF18822.1 EPS31870.1 - 1 9.2 41.2 1.2 8.9 1.8 6.1 1 1 4 6 6 6 0 CdvA-like coiled-coil domain Fib_alpha PF08702.10 EPS31870.1 - 1.1 9.5 30.7 5.5 7.2 3.1 4.1 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family NPV_P10 PF05531.12 EPS31870.1 - 2.9 8.4 20.8 3 8.4 0.4 5.2 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.6 EPS31870.1 - 3.2 7.0 55.2 0.33 10.3 15.9 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Syntaxin_2 PF14523.6 EPS31870.1 - 9.1 6.7 33.8 0.22 11.9 10.0 3.7 2 1 1 3 3 3 0 Syntaxin-like protein Laminin_I PF06008.14 EPS31870.1 - 9.7 5.8 50.9 2.9 7.5 7.6 4.2 1 1 2 4 4 4 0 Laminin Domain I Fanconi_A_N PF15865.5 EPS31871.1 - 0.061 12.7 0.0 0.072 12.5 0.0 1.0 1 0 0 1 1 1 0 Fanconi anaemia group A protein N terminus DUF5056 PF16479.5 EPS31872.1 - 0.093 13.0 3.6 1.6 9.0 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5056) DAO PF01266.24 EPS31873.1 - 3.3e-50 171.7 0.0 4.6e-50 171.2 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 EPS31873.1 - 6.8e-44 148.8 0.1 1.1e-43 148.1 0.1 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 EPS31873.1 - 2.4e-09 36.8 0.3 6.7e-09 35.3 0.3 1.7 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EPS31873.1 - 0.00031 20.2 0.3 0.00059 19.3 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPS31873.1 - 0.002 17.4 0.0 0.0046 16.2 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPS31873.1 - 0.0085 16.3 0.2 0.0085 16.3 0.2 2.5 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 EPS31873.1 - 0.013 15.4 0.2 0.025 14.4 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 EPS31873.1 - 0.031 13.0 0.3 0.062 12.0 0.3 1.5 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.6 EPS31873.1 - 0.051 12.8 0.0 0.13 11.5 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPS31873.1 - 0.059 13.9 0.2 0.18 12.4 0.2 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EPS31873.1 - 0.097 11.7 0.6 0.35 9.9 0.6 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Sacchrp_dh_NADP PF03435.18 EPS31873.1 - 0.19 12.0 0.0 0.41 10.9 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Ecl1 PF12855.7 EPS31876.1 - 1.2e-08 36.4 20.8 3.6e-08 34.8 20.8 1.6 1 1 0 1 1 1 1 ECL1/2/3 zinc binding proteins CCDC106 PF15794.5 EPS31876.1 - 3.8 7.2 8.5 4.4 7.0 8.5 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 DASH_Dad2 PF08654.10 EPS31879.1 - 2.4e-26 92.1 4.7 3e-25 88.5 1.5 2.1 1 1 1 2 2 2 2 DASH complex subunit Dad2 DASH_Duo1 PF08651.10 EPS31879.1 - 0.054 13.3 0.1 0.076 12.8 0.1 1.1 1 0 0 1 1 1 0 DASH complex subunit Duo1 CK2S PF15011.6 EPS31879.1 - 0.061 13.2 0.1 0.068 13.1 0.1 1.1 1 0 0 1 1 1 0 Casein Kinase 2 substrate Shugoshin_N PF07558.11 EPS31880.1 - 4.8e-18 64.8 3.0 9e-18 63.9 3.0 1.5 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 EPS31880.1 - 1.3e-10 40.9 6.2 1.3e-10 40.9 6.2 3.0 2 0 0 2 2 2 1 Shugoshin C terminus DivIC PF04977.15 EPS31880.1 - 0.0093 15.7 0.4 0.063 13.0 0.3 2.4 2 0 0 2 2 2 1 Septum formation initiator HAP1_N PF04849.13 EPS31880.1 - 0.023 13.9 0.4 0.041 13.1 0.4 1.3 1 0 0 1 1 1 0 HAP1 N-terminal conserved region bZIP_2 PF07716.15 EPS31880.1 - 0.034 14.2 0.7 0.034 14.2 0.7 2.7 4 0 0 4 4 4 0 Basic region leucine zipper Snapin_Pallidin PF14712.6 EPS31880.1 - 0.052 14.0 0.6 0.11 12.9 0.6 1.6 1 0 0 1 1 1 0 Snapin/Pallidin GAS PF13851.6 EPS31880.1 - 0.067 12.5 0.7 0.14 11.5 0.7 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.21 EPS31880.1 - 0.074 13.2 0.5 0.074 13.2 0.5 3.0 3 0 0 3 3 3 0 bZIP transcription factor GIT_CC PF16559.5 EPS31880.1 - 1.6 8.7 6.2 0.33 10.8 0.6 2.7 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor PPI_Ypi1 PF07491.11 EPS31881.1 - 5.3e-26 90.2 4.2 1.3e-25 89.0 4.2 1.7 1 1 0 1 1 1 1 Protein phosphatase inhibitor CRM1_C PF08767.11 EPS31882.1 - 2.5e-136 454.0 7.8 2.5e-136 454.0 7.8 3.1 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 EPS31882.1 - 2.7e-41 141.1 5.9 2.7e-41 141.1 5.9 4.1 4 1 1 5 5 5 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 EPS31882.1 - 4e-34 116.1 4.3 2.4e-33 113.6 4.4 2.4 2 0 0 2 2 2 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 EPS31882.1 - 7.8e-30 102.7 1.6 1.8e-29 101.6 0.6 2.3 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 EPS31882.1 - 1.7e-19 69.1 0.6 3.4e-19 68.0 0.6 1.6 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 EPS31882.1 - 4.1e-12 45.8 0.0 2.1e-11 43.5 0.0 2.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.8 EPS31882.1 - 0.0011 18.9 1.0 0.13 12.2 0.0 4.2 4 1 0 4 4 4 1 Domain of unknown function (DUF3385) Hemocyanin_M PF00372.19 EPS31882.1 - 0.027 13.6 0.5 0.089 12.0 0.1 2.0 2 0 0 2 2 2 0 Hemocyanin, copper containing domain BID PF06393.11 EPS31882.1 - 0.053 13.1 0.1 0.18 11.3 0.1 1.9 1 0 0 1 1 1 0 BH3 interacting domain (BID) DRE2_N PF16803.5 EPS31882.1 - 0.075 13.3 0.1 0.51 10.6 0.0 2.5 2 0 0 2 2 2 0 Fe-S cluster assembly protein DRE2 N-terminus HD_assoc PF13286.6 EPS31882.1 - 0.25 11.9 2.0 29 5.3 0.2 4.4 4 1 1 5 5 4 0 Phosphohydrolase-associated domain Mac_assoc PF16628.5 EPS31885.1 - 1.1e-74 250.7 12.3 1.1e-74 250.7 12.3 2.4 2 0 0 2 2 2 1 Unstructured region on maltose acetyltransferase Mac PF12464.8 EPS31885.1 - 9.5e-13 48.2 0.1 1.9e-12 47.2 0.1 1.5 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.6 EPS31885.1 - 7.8e-11 41.5 4.9 2e-05 24.2 0.2 2.7 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Zn_clus PF00172.18 EPS31885.1 - 1.2e-09 38.1 8.2 2.3e-09 37.2 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexapep PF00132.24 EPS31885.1 - 1.3e-08 34.2 5.1 0.0018 17.9 0.2 3.3 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) DUF4907 PF16250.5 EPS31885.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4907) NmrA PF05368.13 EPS31886.1 - 2.9e-06 27.0 0.0 6.1e-06 26.0 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family Zn_clus PF00172.18 EPS31887.1 - 2.1e-08 34.2 11.6 2.1e-08 34.2 11.6 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPS31887.1 - 3e-05 23.2 0.3 0.00024 20.2 0.1 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EPS31887.1 - 0.0022 18.3 0.8 0.0022 18.3 0.8 4.0 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPS31887.1 - 0.0025 18.5 17.1 0.01 16.6 0.6 4.6 5 0 0 5 5 5 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EPS31887.1 - 0.0091 16.4 7.8 0.2 12.1 1.2 2.9 2 0 0 2 2 2 2 Zinc-finger double domain Fungal_trans PF04082.18 EPS31888.1 - 3.2e-07 29.6 0.1 4.8e-07 29.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EPS31889.1 - 1.6e-06 28.2 10.3 0.011 16.1 3.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_3rep PF18868.1 EPS31889.1 - 0.01 16.5 0.7 0.21 12.3 0.3 2.4 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_4 PF13894.6 EPS31889.1 - 0.011 16.6 11.9 0.3 12.0 2.7 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EPS31889.1 - 0.011 16.1 10.6 0.088 13.3 2.5 3.4 3 0 0 3 3 3 0 Zinc-finger double domain PHP_C PF13263.6 EPS31889.1 - 0.14 12.0 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 PHP-associated Ribonuc_L-PSP PF01042.21 EPS31890.1 - 7.6e-19 67.9 0.0 9.6e-19 67.6 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP ALAD PF00490.21 EPS31891.1 - 2.3e-121 404.8 0.0 2.7e-121 404.6 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase A_deaminase PF00962.22 EPS31897.1 - 5.2e-122 407.3 0.0 7.1e-122 406.8 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Dynamin_M PF01031.20 EPS31899.1 - 1.8e-109 365.4 0.0 2.9e-109 364.7 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EPS31899.1 - 1.3e-54 184.7 0.0 2.8e-54 183.7 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 EPS31899.1 - 1.1e-31 108.8 0.6 1.1e-31 108.8 0.6 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EPS31899.1 - 0.00014 21.9 0.1 0.0028 17.7 0.2 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EPS31899.1 - 0.042 13.4 0.1 3.2 7.3 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B UAA PF08449.11 EPS31900.1 - 2e-85 286.7 10.4 1.1e-84 284.3 10.4 1.8 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 EPS31900.1 - 1 9.6 29.5 0.32 11.2 9.3 3.5 2 1 0 2 2 2 0 EamA-like transporter family Rad17 PF03215.15 EPS31901.1 - 2.1e-29 102.8 0.0 3.4e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 EPS31901.1 - 5.4e-05 23.6 0.0 0.00017 22.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 EPS31901.1 - 0.0079 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EPS31901.1 - 0.01 16.3 0.0 0.022 15.2 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EPS31901.1 - 0.012 15.5 0.1 0.86 9.5 0.0 3.1 3 0 0 3 3 3 0 NACHT domain AAA_18 PF13238.6 EPS31901.1 - 0.025 15.1 0.0 0.056 14.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EPS31901.1 - 0.032 14.5 0.0 0.082 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EPS31901.1 - 0.078 13.1 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EPS31901.1 - 0.097 11.7 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.22 EPS31901.1 - 0.11 12.9 0.0 0.25 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 EPS31901.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE dNK PF01712.19 EPS31901.1 - 0.19 11.5 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Deoxynucleoside kinase DUF4177 PF13783.6 EPS31901.1 - 0.2 12.0 0.0 0.55 10.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4177) ELMO_CED12 PF04727.13 EPS31902.1 - 1.7e-49 168.3 0.0 2.8e-49 167.6 0.0 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family PH_12 PF16457.5 EPS31902.1 - 2.3e-32 112.3 0.4 7.1e-32 110.7 0.4 1.9 1 1 0 1 1 1 1 Pleckstrin homology domain DUF3361 PF11841.8 EPS31902.1 - 1.9e-15 57.2 0.0 4.5e-15 55.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) SprA-related PF12118.8 EPS31902.1 - 0.91 8.6 5.5 1.7 7.7 5.5 1.4 1 0 0 1 1 1 0 SprA-related family DUF1752 PF08550.10 EPS31903.1 - 2.2e-11 43.4 4.5 4.3e-11 42.4 4.5 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) SUI1 PF01253.22 EPS31906.1 - 2.5e-24 85.6 0.3 5e-24 84.6 0.3 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 Img2 PF05046.14 EPS31906.1 - 0.0081 16.4 0.5 0.014 15.6 0.3 1.7 1 1 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) TnpV PF14198.6 EPS31906.1 - 0.035 14.1 0.1 0.065 13.2 0.1 1.5 1 0 0 1 1 1 0 Transposon-encoded protein TnpV Spc7 PF08317.11 EPS31907.1 - 0.042 12.7 3.2 0.065 12.1 3.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein GAS PF13851.6 EPS31907.1 - 0.055 12.8 5.7 0.022 14.1 2.9 1.6 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Syntaxin-6_N PF09177.11 EPS31907.1 - 0.055 14.0 9.3 2.8 8.6 1.4 3.7 3 1 1 4 4 3 0 Syntaxin 6, N-terminal Baculo_PEP_C PF04513.12 EPS31907.1 - 0.065 13.3 1.3 0.24 11.5 1.0 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FUSC PF04632.12 EPS31907.1 - 0.083 11.4 4.8 0.13 10.7 4.8 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF2207 PF09972.9 EPS31907.1 - 0.087 11.6 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF5623 PF18536.1 EPS31907.1 - 0.1 12.9 0.4 1.4 9.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5623) HsbA PF12296.8 EPS31907.1 - 0.12 12.8 0.1 0.29 11.6 0.1 1.6 1 0 0 1 1 1 0 Hydrophobic surface binding protein A DUF1664 PF07889.12 EPS31907.1 - 0.12 12.4 0.2 0.67 10.0 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) AAA_13 PF13166.6 EPS31907.1 - 0.12 10.9 1.9 0.17 10.5 1.9 1.1 1 0 0 1 1 1 0 AAA domain Snf7 PF03357.21 EPS31907.1 - 0.19 11.3 2.3 0.35 10.4 2.3 1.4 1 0 0 1 1 1 0 Snf7 Fzo_mitofusin PF04799.13 EPS31907.1 - 0.2 11.2 1.0 0.72 9.4 0.8 1.9 1 1 1 2 2 2 0 fzo-like conserved region TMPIT PF07851.13 EPS31907.1 - 0.32 10.2 0.4 0.55 9.4 0.4 1.3 1 0 0 1 1 1 0 TMPIT-like protein CENP-F_leu_zip PF10473.9 EPS31907.1 - 0.43 10.6 7.2 0.23 11.5 4.4 1.9 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Exonuc_VII_L PF02601.15 EPS31907.1 - 0.63 9.6 3.9 1.1 8.8 3.9 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spectrin PF00435.21 EPS31907.1 - 1.1 9.8 6.8 19 5.8 3.1 2.5 1 1 1 2 2 2 0 Spectrin repeat DUF3552 PF12072.8 EPS31907.1 - 1.2 8.5 6.0 0.24 10.8 2.6 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Jnk-SapK_ap_N PF09744.9 EPS31907.1 - 1.3 9.2 9.6 0.54 10.5 5.7 2.1 1 1 0 2 2 2 0 JNK_SAPK-associated protein-1 Snapin_Pallidin PF14712.6 EPS31907.1 - 1.8 9.0 6.7 0.35 11.3 1.2 2.5 3 0 0 3 3 2 0 Snapin/Pallidin TPR_MLP1_2 PF07926.12 EPS31907.1 - 2 8.5 9.2 0.48 10.5 5.5 1.8 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein ZapB PF06005.12 EPS31907.1 - 2.3 8.7 12.1 3.7 8.1 0.3 3.3 3 0 0 3 3 3 0 Cell division protein ZapB DHR10 PF18595.1 EPS31907.1 - 4.1 7.5 9.5 0.82 9.7 2.9 2.7 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain Csm1_N PF18504.1 EPS31907.1 - 8.4 6.8 6.1 0.74 10.2 0.5 2.1 2 1 1 3 3 2 0 Csm1 N-terminal domain Cgr1 PF03879.14 EPS31908.1 - 4.7e-33 113.8 31.0 5.3e-33 113.6 31.0 1.0 1 0 0 1 1 1 1 Cgr1 family Y2_Tnp PF04986.13 EPS31908.1 - 0.13 12.3 5.3 0.16 12.1 5.3 1.0 1 0 0 1 1 1 0 Putative transposase RRT14 PF17075.5 EPS31908.1 - 0.46 10.6 14.3 0.57 10.3 14.3 1.1 1 0 0 1 1 1 0 Regular of rDNA transcription protein 14 CDC27 PF09507.10 EPS31908.1 - 1.2 8.4 19.1 1.4 8.2 19.1 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF4192 PF13830.6 EPS31908.1 - 1.3 9.0 7.2 1.5 8.8 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) VIT1 PF01988.19 EPS31908.1 - 3 7.6 6.9 4 7.3 6.9 1.1 1 0 0 1 1 1 0 VIT family RR_TM4-6 PF06459.12 EPS31908.1 - 4 7.2 13.8 4.2 7.1 13.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM176 PF14851.6 EPS31908.1 - 4.8 6.8 12.5 6.2 6.5 12.5 1.1 1 0 0 1 1 1 0 FAM176 family Pannexin_like PF12534.8 EPS31908.1 - 9.9 5.1 8.4 12 4.9 8.4 1.0 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Mito_carr PF00153.27 EPS31909.1 - 5.6e-63 208.9 0.6 1.5e-21 76.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein dCMP_cyt_deam_1 PF00383.23 EPS31910.1 - 3.9e-13 49.1 0.5 4.7e-13 48.9 0.5 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 EPS31910.1 - 1.1e-10 41.8 1.9 2.7e-08 34.1 0.3 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 EPS31910.1 - 0.00096 18.8 0.4 1.1 8.8 0.1 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases Sortilin-Vps10 PF15902.5 EPS31911.1 - 5.9e-270 895.4 11.1 7.6e-140 466.6 3.4 2.1 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 EPS31911.1 - 2.2e-90 301.5 15.8 2.3e-46 158.2 6.4 2.4 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 EPS31911.1 - 4.1e-07 29.0 29.0 0.73 10.1 0.1 10.3 10 0 0 10 10 10 3 BNR/Asp-box repeat BNR_2 PF13088.6 EPS31911.1 - 0.00017 21.0 4.7 1.3 8.2 0.0 6.0 6 1 1 7 7 7 2 BNR repeat-like domain DUF2167 PF09935.9 EPS31911.1 - 0.026 13.7 0.1 0.28 10.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2167) Sec10 PF07393.11 EPS31915.1 - 1.1e-232 774.4 0.0 1.3e-232 774.2 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 MarR_2 PF12802.7 EPS31915.1 - 0.014 15.3 0.2 2.5 8.0 0.0 3.0 2 0 0 2 2 2 0 MarR family Baculo_PEP_C PF04513.12 EPS31915.1 - 0.21 11.6 3.0 8 6.5 0.1 3.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prenyltransf PF01255.19 EPS31916.1 - 0.086 12.4 0.0 0.4 10.2 0.0 1.9 2 0 0 2 2 2 0 Putative undecaprenyl diphosphate synthase HSP33 PF01430.19 EPS31916.1 - 0.1 12.0 0.0 0.43 10.0 0.1 1.7 1 1 1 2 2 2 0 Hsp33 protein Whib PF02467.16 EPS31917.1 - 0.048 14.3 0.0 0.048 14.3 0.0 2.2 2 1 0 2 2 2 0 Transcription factor WhiB Fungal_trans PF04082.18 EPS31919.1 - 8e-20 71.0 0.0 1.3e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS31919.1 - 3.3e-07 30.3 12.8 5.6e-07 29.6 12.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fringe PF02434.16 EPS31920.1 - 5.8e-08 32.5 0.6 7.4e-05 22.3 0.2 3.1 2 1 0 2 2 2 2 Fringe-like PAN_1 PF00024.26 EPS31920.1 - 5.1e-05 23.2 0.1 0.00011 22.1 0.1 1.5 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 EPS31920.1 - 0.00064 19.6 0.7 0.0015 18.4 0.7 1.6 1 0 0 1 1 1 1 PAN domain MASE2 PF05230.11 EPS31920.1 - 0.16 12.1 0.2 0.39 10.8 0.2 1.6 1 0 0 1 1 1 0 MASE2 domain MFS_1 PF07690.16 EPS31921.1 - 4.5e-23 81.7 62.1 1e-21 77.3 45.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EPS31921.1 - 0.0026 16.1 0.5 0.0026 16.1 0.5 2.8 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Methyltransf_2 PF00891.18 EPS31922.1 - 1.3e-11 44.3 0.0 2.6e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 O-methyltransferase domain Rep_1B PF17873.1 EPS31923.1 - 0.72 9.8 4.0 1.6 8.7 0.7 2.5 2 0 0 2 2 2 0 Replicase polyprotein 1ab MFS_1 PF07690.16 EPS31925.1 - 9.1e-34 116.9 33.2 1.8e-32 112.7 33.2 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Holin_BhlA PF10960.8 EPS31925.1 - 0.008 16.1 0.0 0.019 14.9 0.0 1.6 1 0 0 1 1 1 1 BhlA holin family ESSS PF10183.9 EPS31925.1 - 0.011 15.9 0.2 0.25 11.5 0.0 3.1 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF3619 PF12279.8 EPS31925.1 - 0.14 12.4 0.0 0.32 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3619) FAD_binding_3 PF01494.19 EPS31928.1 - 1.2e-13 51.0 0.0 0.0014 18.0 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.6 EPS31928.1 - 3e-06 27.4 0.0 9.1e-06 25.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EPS31928.1 - 9.9e-05 21.7 0.0 0.35 10.1 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EPS31928.1 - 0.0052 16.1 0.0 0.0097 15.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 EPS31928.1 - 0.013 16.1 0.0 0.5 11.0 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EPS31928.1 - 0.03 13.6 0.1 3.9 6.6 0.0 2.6 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase DAO PF01266.24 EPS31928.1 - 0.058 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EPS31928.1 - 0.15 10.7 0.0 3.7 6.1 0.0 2.4 2 0 0 2 2 2 0 HI0933-like protein Fungal_trans PF04082.18 EPS31929.1 - 1.8e-23 82.9 1.2 3.1e-23 82.1 1.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS31929.1 - 2.1e-07 30.9 8.0 4.7e-07 29.8 8.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RIC3 PF15361.6 EPS31929.1 - 0.098 13.1 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 ALIX_LYPXL_bnd PF13949.6 EPS31929.1 - 0.12 11.7 3.1 0.079 12.2 0.4 2.0 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV Na_H_Exchanger PF00999.21 EPS31930.1 - 3.6e-36 124.8 12.1 4.6e-36 124.4 12.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.6 EPS31930.1 - 0.0068 16.5 0.8 0.019 15.0 0.2 2.1 2 0 0 2 2 2 1 YrhC-like protein MAPEG PF01124.18 EPS31931.1 - 5.9e-15 55.3 1.6 9.6e-15 54.6 1.6 1.3 1 1 0 1 1 1 1 MAPEG family Glyco_hydro_28 PF00295.17 EPS31932.1 - 7.7e-54 182.9 4.7 1.1e-53 182.5 4.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF4528 PF15031.6 EPS31932.1 - 0.029 14.4 0.1 0.078 13.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4528) YabP PF07873.11 EPS31932.1 - 0.067 13.0 0.7 0.28 11.0 0.1 2.4 3 0 0 3 3 3 0 YabP family MFS_1 PF07690.16 EPS31933.1 - 9.9e-32 110.2 33.7 9.9e-32 110.2 33.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS31933.1 - 6.8e-09 35.1 14.5 6.8e-09 35.1 14.5 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.13 EPS31933.1 - 1.3e-05 23.8 6.5 1.3e-05 23.8 6.5 2.3 2 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF4668 PF15701.5 EPS31933.1 - 0.003 17.4 0.0 0.054 13.3 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4668) MMPL PF03176.15 EPS31933.1 - 0.039 12.9 0.3 0.039 12.9 0.3 2.3 2 0 0 2 2 2 0 MMPL family p450 PF00067.22 EPS31935.1 - 1.7e-70 238.0 0.0 2.4e-70 237.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 EPS31936.1 - 1.8e-37 128.7 0.1 6.9e-37 126.8 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS31936.1 - 1e-26 94.0 0.0 1.5e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPS31936.1 - 3.8e-07 30.2 0.4 0.025 14.5 0.0 2.4 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 EPS31936.1 - 0.00031 20.3 0.0 0.00052 19.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family UPF0146 PF03686.13 EPS31936.1 - 0.0096 15.8 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0146) 2-Hacid_dh_C PF02826.19 EPS31936.1 - 0.079 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Abhydrolase_3 PF07859.13 EPS31937.1 - 1.2e-22 80.8 0.0 1.8e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EPS31937.1 - 4.5e-15 55.4 0.0 7e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 EPS31937.1 - 0.025 14.1 0.0 0.048 13.1 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2974 PF11187.8 EPS31937.1 - 0.026 14.1 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF1609 PF07753.11 EPS31937.1 - 0.19 11.3 0.0 0.26 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1609) FMO-like PF00743.19 EPS31938.1 - 1.3e-20 73.3 0.0 1.4e-18 66.7 0.0 2.2 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EPS31938.1 - 2.9e-15 56.3 0.1 6.6e-15 55.2 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EPS31938.1 - 2.3e-12 46.8 0.0 2.3e-10 40.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPS31938.1 - 3.8e-11 43.1 0.0 1.6e-07 31.5 0.0 3.4 4 0 0 4 4 4 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EPS31938.1 - 1.5e-09 37.5 0.2 1.4e-07 31.0 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EPS31938.1 - 2.4e-08 34.0 0.9 0.00011 21.9 0.1 4.0 3 1 1 5 5 5 1 FAD dependent oxidoreductase Thi4 PF01946.17 EPS31938.1 - 8.2e-08 31.8 0.0 1.8e-05 24.1 0.0 2.4 3 0 0 3 3 3 1 Thi4 family Lycopene_cycl PF05834.12 EPS31938.1 - 1.7e-07 30.7 0.0 0.099 11.7 0.0 4.0 4 0 0 4 4 4 3 Lycopene cyclase protein Pyr_redox PF00070.27 EPS31938.1 - 0.00011 22.7 0.0 0.0085 16.6 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 EPS31938.1 - 0.0073 16.4 0.1 0.029 14.4 0.0 2.0 3 0 0 3 3 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.24 EPS31938.1 - 0.013 14.6 0.0 0.22 10.6 0.0 2.6 3 0 0 3 3 3 0 FAD binding domain Mqo PF06039.15 EPS31938.1 - 0.014 14.0 0.1 0.75 8.3 0.1 2.4 2 1 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Pex2_Pex12 PF04757.14 EPS31938.1 - 0.015 14.9 0.4 0.025 14.2 0.4 1.3 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region NAD_binding_9 PF13454.6 EPS31938.1 - 0.016 15.2 2.1 9.8 6.1 0.0 3.6 4 1 0 4 4 4 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 EPS31938.1 - 0.042 14.3 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding GIDA PF01134.22 EPS31938.1 - 0.11 11.6 0.3 9.5 5.2 0.0 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A PTR2 PF00854.21 EPS31940.1 - 4.7e-81 272.6 4.7 5.3e-81 272.5 4.1 1.4 1 1 0 1 1 1 1 POT family DUF4293 PF14126.6 EPS31940.1 - 0.071 13.4 0.1 0.22 11.7 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) E1-E2_ATPase PF00122.20 EPS31940.1 - 0.35 10.4 1.1 5.5 6.5 0.2 2.4 2 0 0 2 2 2 0 E1-E2 ATPase Iwr1 PF08574.10 EPS31943.1 - 3.9e-21 75.8 10.2 3.9e-21 75.8 10.2 3.0 3 0 0 3 3 3 1 Transcription factor Iwr1 RRM_1 PF00076.22 EPS31945.1 - 1e-39 134.2 0.0 6.8e-12 45.0 0.1 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EPS31945.1 - 2.3e-14 53.0 0.0 0.0016 18.3 0.0 4.3 4 0 0 4 4 4 3 Occluded RNA-recognition motif RRM PF10378.9 EPS31945.1 - 4.5e-08 32.7 0.9 2.6e-07 30.3 0.9 2.4 1 0 0 1 1 1 1 Putative RRM domain DUF4523 PF15023.6 EPS31945.1 - 2.6e-05 24.1 0.0 0.23 11.3 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF4523) RRM_3 PF08777.11 EPS31945.1 - 8.1e-05 22.6 0.0 0.4 10.8 0.0 3.1 3 0 0 3 3 3 2 RNA binding motif RRM_7 PF16367.5 EPS31945.1 - 0.00058 19.9 0.0 1.1 9.5 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif RRM_Rrp7 PF17799.1 EPS31945.1 - 0.0046 16.8 0.0 1.5 8.6 0.0 3.7 2 1 2 4 4 4 1 Rrp7 RRM-like N-terminal domain RNA_bind PF08675.11 EPS31945.1 - 0.13 12.3 0.1 1.1 9.3 0.0 2.5 4 0 0 4 4 4 0 RNA binding domain Nup35_RRM_2 PF14605.6 EPS31945.1 - 0.2 11.7 0.0 75 3.4 0.0 3.4 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif SLM4 PF16818.5 EPS31945.1 - 0.35 10.8 2.9 9.3 6.2 1.3 2.2 2 0 0 2 2 2 0 Protein SLM4 Stealth_CR4 PF17103.5 EPS31946.1 - 0.0013 18.5 0.6 0.0018 18.2 0.6 1.3 1 0 0 1 1 1 1 Stealth protein CR4, conserved region 4 tRNA-synt_2 PF00152.20 EPS31948.1 - 1.5e-88 296.9 0.0 2.5e-88 296.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EPS31948.1 - 3.7e-07 30.0 0.0 6.7e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain HNF-1_N PF04814.13 EPS31950.1 - 0.048 14.3 0.6 0.49 11.0 0.0 2.0 1 1 1 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus DUF935 PF06074.12 EPS31950.1 - 0.11 11.2 0.1 0.12 11.1 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF935) Fungal_trans PF04082.18 EPS31954.1 - 3.3e-18 65.7 0.1 9.1e-18 64.2 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS31954.1 - 0.035 14.2 3.7 0.067 13.3 3.7 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.25 EPS31955.1 - 0.00015 21.2 0.0 0.00073 19.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS31955.1 - 0.0012 18.2 0.0 0.0014 18.0 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EPS31955.1 - 0.023 14.6 0.5 0.056 13.4 0.4 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EPS31955.1 - 0.07 11.9 0.1 0.1 11.3 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase Aldo_ket_red PF00248.21 EPS31956.1 - 2e-47 161.8 0.0 2.9e-47 161.3 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family NmrA PF05368.13 EPS31956.1 - 0.047 13.2 0.1 0.077 12.5 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family SO_alpha_A3 PF17806.1 EPS31956.1 - 0.085 13.2 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Sarcosine oxidase A3 domain PgaD PF13994.6 EPS31957.1 - 0.021 14.9 0.0 0.024 14.7 0.0 1.3 1 0 0 1 1 1 0 PgaD-like protein Ecl1 PF12855.7 EPS31958.1 - 3.8e-39 135.6 36.7 6.3e-23 82.8 7.8 3.1 2 1 1 3 3 3 2 ECL1/2/3 zinc binding proteins zf-MYND PF01753.18 EPS31958.1 - 0.0024 17.9 0.5 0.0059 16.7 0.5 1.6 1 0 0 1 1 1 1 MYND finger PLATZ PF04640.14 EPS31958.1 - 0.059 14.0 0.4 0.12 13.0 0.4 1.4 1 0 0 1 1 1 0 PLATZ transcription factor zf-FLZ PF04570.14 EPS31958.1 - 0.13 11.8 4.4 0.51 9.9 4.4 1.8 1 1 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 DUF2256 PF10013.9 EPS31958.1 - 0.38 10.9 5.7 5.4 7.2 5.7 2.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2256) YL1 PF05764.13 EPS31959.1 - 7.1e-60 203.1 22.6 7.1e-60 203.1 22.6 3.3 2 1 1 3 3 3 1 YL1 nuclear protein YL1_C PF08265.11 EPS31959.1 - 3.3e-13 49.1 0.2 5.8e-13 48.3 0.2 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Chitin_bind_4 PF00379.23 EPS31959.1 - 0.28 11.8 1.5 0.74 10.4 0.2 2.5 2 0 0 2 2 2 0 Insect cuticle protein PUF PF00806.19 EPS31961.1 - 8.6e-25 85.0 0.0 0.00011 21.7 0.0 6.1 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 EPS31961.1 - 4.4e-10 39.2 0.0 9.4e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MT-A70 PF05063.14 EPS31962.1 - 1.5e-18 67.3 0.0 3.9e-17 62.7 0.0 2.4 1 1 0 1 1 1 1 MT-A70 MFS_1 PF07690.16 EPS31963.1 - 2.3e-37 128.7 50.0 2.3e-37 128.7 50.0 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Peptidase_C12 PF01088.21 EPS31964.1 - 2.8e-56 190.6 0.0 3.4e-56 190.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DcpS PF05652.12 EPS31965.1 - 5e-36 123.7 0.0 8.7e-36 122.9 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 EPS31965.1 - 1.3e-31 109.4 0.1 2.2e-31 108.7 0.1 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding RNase_H2_suC PF08615.11 EPS31966.1 - 7.1e-32 110.5 0.0 9e-32 110.2 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Nop53 PF07767.11 EPS31967.1 - 1e-105 354.4 33.7 1.5e-105 353.9 33.7 1.3 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Myb_Cef PF11831.8 EPS31968.1 - 1.7e-59 201.3 5.0 1.7e-59 201.3 5.0 3.0 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 EPS31968.1 - 1.6e-23 82.6 3.6 6.6e-11 42.2 0.6 3.6 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EPS31968.1 - 1.3e-20 73.4 3.2 1.2e-13 51.1 0.7 3.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 EPS31968.1 - 0.085 13.0 3.0 0.27 11.4 0.0 3.1 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain HTH_AsnC-type PF13404.6 EPS31968.1 - 0.09 12.6 2.2 0.79 9.6 0.0 2.9 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain MOZ_SAS PF01853.18 EPS31969.1 - 3.7e-80 267.8 0.0 5.1e-80 267.4 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.8 EPS31969.1 - 4.6e-23 80.9 0.0 1.2e-22 79.5 0.0 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-MYST PF17772.1 EPS31969.1 - 1.7e-21 75.6 0.4 3.4e-21 74.6 0.4 1.5 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 EPS31969.1 - 0.061 13.8 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPS31969.1 - 0.11 12.7 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Aa_trans PF01490.18 EPS31970.1 - 9e-25 87.2 34.5 6.1e-24 84.5 34.5 2.1 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein YpmT PF17431.2 EPS31970.1 - 0.11 12.5 0.1 0.11 12.5 0.1 3.4 3 0 0 3 3 3 0 Uncharacterized YmpT-like Pox_A14 PF05767.12 EPS31970.1 - 8 6.7 8.6 0.65 10.2 0.3 2.8 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 F1F0-ATPsyn_F PF10791.9 EPS31975.1 - 1.4e-39 134.4 0.1 1.6e-39 134.2 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi ETC_C1_NDUFA4 PF04800.12 EPS31976.1 - 5.1e-37 126.0 1.5 7.1e-37 125.6 1.5 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region DUF2188 PF09954.9 EPS31976.1 - 0.026 14.7 0.1 0.056 13.6 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) HEAT_2 PF13646.6 EPS31977.1 - 1.5e-29 102.2 0.0 1.5e-12 47.7 0.4 3.5 2 2 2 4 4 4 3 HEAT repeats HEAT_PBS PF03130.16 EPS31977.1 - 2.3e-17 61.9 10.3 0.0063 17.1 0.5 7.2 8 0 0 8 8 8 5 PBS lyase HEAT-like repeat HEAT PF02985.22 EPS31977.1 - 1.3e-10 40.5 0.2 0.87 10.0 0.0 6.2 6 0 0 6 6 6 4 HEAT repeat HEAT_EZ PF13513.6 EPS31977.1 - 0.0025 18.3 6.5 13 6.4 0.0 5.7 4 2 2 6 6 6 1 HEAT-like repeat RuvA_C PF07499.13 EPS31977.1 - 0.021 15.3 2.0 2.1 8.9 0.1 3.1 3 0 0 3 3 3 0 RuvA, C-terminal domain Cnd1 PF12717.7 EPS31977.1 - 0.023 14.8 0.0 6.8 6.7 0.0 2.9 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 TFIIS_C PF01096.18 EPS31978.1 - 4.9e-14 51.9 1.3 4.9e-14 51.9 1.3 3.4 4 0 0 4 4 4 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EPS31978.1 - 2.6e-07 30.4 0.4 2.6e-07 30.4 0.4 2.9 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TF_Zn_Ribbon PF08271.12 EPS31978.1 - 0.0023 17.4 3.1 0.87 9.1 0.1 3.4 3 0 0 3 3 3 2 TFIIB zinc-binding Zn_ribbon_recom PF13408.6 EPS31978.1 - 0.005 17.3 5.8 0.39 11.3 0.3 2.4 2 1 0 2 2 2 2 Recombinase zinc beta ribbon domain zinc_ribbon_2 PF13240.6 EPS31978.1 - 0.018 14.7 9.1 2.1 8.1 0.1 3.7 4 0 0 4 4 4 0 zinc-ribbon domain DZR PF12773.7 EPS31978.1 - 0.025 14.6 4.6 0.15 12.1 0.1 2.5 2 1 0 2 2 2 0 Double zinc ribbon tRNA-synt_1f PF01921.18 EPS31978.1 - 0.037 13.0 0.6 0.048 12.6 0.1 1.4 2 0 0 2 2 2 0 tRNA synthetases class I (K) zf-RRPl_C4 PF17026.5 EPS31978.1 - 0.037 14.1 0.5 0.19 11.8 0.1 2.0 1 1 1 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type C1_1 PF00130.22 EPS31978.1 - 0.044 13.7 0.2 0.044 13.7 0.2 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Nudix_N_2 PF14803.6 EPS31978.1 - 0.061 13.2 2.0 0.061 13.2 2.0 3.0 3 1 1 4 4 4 0 Nudix N-terminal GFA PF04828.14 EPS31978.1 - 0.25 11.7 6.0 1.1 9.6 1.7 2.4 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Zn-ribbon_8 PF09723.10 EPS31978.1 - 0.49 10.6 0.2 0.49 10.6 0.2 2.6 3 0 0 3 3 2 0 Zinc ribbon domain RNHCP PF12647.7 EPS31978.1 - 1.5 8.9 6.1 15 5.7 3.5 2.8 1 1 1 2 2 2 0 RNHCP domain Zn_ribbon_SprT PF17283.2 EPS31978.1 - 1.8 8.6 13.2 6.4 6.8 0.0 4.0 3 1 0 3 3 3 0 SprT-like zinc ribbon domain Elf1 PF05129.13 EPS31978.1 - 3 7.9 6.4 4.6 7.4 1.0 2.6 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Nipped-B_C PF12830.7 EPS31979.1 - 1e-48 165.8 2.6 3.8e-47 160.7 1.1 3.1 2 1 1 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 EPS31979.1 - 9.4e-11 41.8 1.7 9.4e-11 41.8 1.7 3.1 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 EPS31979.1 - 0.0001 22.4 0.4 0.074 13.1 0.0 3.1 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Cnd3 PF12719.7 EPS31979.1 - 0.008 15.4 1.8 2.6 7.2 0.0 3.5 4 0 0 4 4 4 2 Nuclear condensing complex subunits, C-term domain HEAT PF02985.22 EPS31979.1 - 0.013 15.7 7.9 0.78 10.2 0.2 5.4 5 0 0 5 5 5 0 HEAT repeat Adaptin_N PF01602.20 EPS31979.1 - 0.033 12.8 6.0 0.017 13.7 0.8 2.9 3 1 0 3 3 3 0 Adaptin N terminal region Sec7_N PF12783.7 EPS31979.1 - 8.4 6.3 7.2 38 4.2 0.1 4.6 6 1 0 6 6 6 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Pyr_redox_2 PF07992.14 EPS31980.1 - 5.9e-41 140.6 0.0 8.2e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPS31980.1 - 6.4e-13 49.1 0.0 3.3e-11 43.6 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 EPS31980.1 - 7.8e-06 25.1 0.0 5.3e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 EPS31980.1 - 3.5e-05 24.2 0.0 0.0001 22.7 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EPS31980.1 - 0.00012 21.7 0.2 0.00043 20.0 0.2 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_5 PF13202.6 EPS31980.1 - 0.00048 19.5 0.3 0.0015 17.9 0.1 2.0 2 0 0 2 2 2 1 EF hand Pyr_redox_3 PF13738.6 EPS31980.1 - 0.13 11.5 1.7 1.2 8.4 1.7 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CLTH PF10607.9 EPS31981.1 - 4.1e-32 111.1 0.1 5.2e-32 110.8 0.1 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EPS31981.1 - 2.5e-08 33.6 0.0 4.4e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 LisH DUF4455 PF14643.6 EPS31981.1 - 0.16 10.6 0.1 0.26 9.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4455) PRK PF00485.18 EPS31982.1 - 1.3e-58 198.0 0.0 1.9e-58 197.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 EPS31982.1 - 3.9e-41 140.8 0.0 7.5e-41 139.9 0.0 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_18 PF13238.6 EPS31982.1 - 9.1e-06 26.2 0.0 1.9e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain CPT PF07931.12 EPS31982.1 - 0.0004 20.3 0.0 0.0009 19.1 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.6 EPS31982.1 - 0.0041 17.3 0.0 0.0076 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EPS31982.1 - 0.013 14.8 0.0 0.031 13.6 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.6 EPS31982.1 - 0.013 15.9 0.1 4.6 7.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 EPS31982.1 - 0.047 13.6 0.2 1.1 9.1 0.1 2.5 3 0 0 3 3 3 0 Adenylylsulphate kinase Cytidylate_kin PF02224.18 EPS31982.1 - 0.063 13.0 0.0 1 9.1 0.0 2.1 2 0 0 2 2 2 0 Cytidylate kinase DUF87 PF01935.17 EPS31982.1 - 0.092 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain NB-ARC PF00931.22 EPS31982.1 - 0.12 11.5 0.2 0.26 10.5 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain AAA_5 PF07728.14 EPS31982.1 - 0.13 12.3 0.0 0.71 9.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EPS31982.1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_16 PF13191.6 EPS31982.1 - 0.13 12.6 0.0 0.36 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain NUC153 PF08159.12 EPS31983.1 - 1.1e-15 57.2 11.9 8.3e-15 54.3 0.9 3.6 3 0 0 3 3 3 3 NUC153 domain FNIP_N PF14636.6 EPS31984.1 - 5.8e-24 85.8 0.4 5.8e-24 85.8 0.4 3.8 4 1 0 4 4 4 1 Folliculin-interacting protein N-terminus FNIP_M PF14637.6 EPS31984.1 - 0.024 14.7 0.0 0.092 12.7 0.0 1.8 1 1 1 2 2 2 0 Folliculin-interacting protein middle domain Glyco_hydro_31 PF01055.26 EPS31985.1 - 1.9e-113 380.0 1.7 2.5e-113 379.6 1.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EPS31985.1 - 2.4e-19 69.4 0.0 1.3e-18 67.1 0.2 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like IML1 PF12257.8 EPS31986.1 - 4.5e-115 383.7 0.0 6.7e-115 383.1 0.0 1.3 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 EPS31986.1 - 1.1e-28 99.1 0.9 2.1e-28 98.1 0.9 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) CsrA PF02599.16 EPS31986.1 - 0.06 13.3 0.0 6.1 6.9 0.0 2.5 2 0 0 2 2 2 0 Global regulator protein family Fungal_trans PF04082.18 EPS31988.1 - 6.6e-15 54.8 0.0 2e-14 53.3 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS31988.1 - 4.1e-07 30.0 13.6 7.7e-07 29.1 13.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CNOT11 PF10155.9 EPS31988.1 - 0.041 14.0 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 CCR4-NOT transcription complex subunit 11 Fungal_trans PF04082.18 EPS31989.1 - 2.3e-17 62.9 1.0 4.1e-17 62.1 1.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS31989.1 - 0.0004 20.4 6.1 0.00076 19.5 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EPS31990.1 - 4e-38 131.3 30.1 4e-38 131.3 30.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.13 EPS31990.1 - 0.43 8.9 19.0 0.0082 14.6 9.0 2.4 2 1 1 3 3 3 0 Transmembrane secretion effector MFS_1 PF07690.16 EPS31991.1 - 7.3e-23 81.0 33.4 7.3e-23 81.0 33.4 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS31991.1 - 6.8e-05 21.9 8.2 6.8e-05 21.9 8.2 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter Glyco_hydro_72 PF03198.14 EPS31992.1 - 7e-127 423.0 7.6 9.4e-127 422.6 7.6 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 EPS31992.1 - 8.5e-20 71.2 0.8 2.6e-19 69.6 0.8 1.9 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.18 EPS31992.1 - 0.002 17.6 0.4 0.0076 15.7 0.4 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) L27_2 PF09045.10 EPS31993.1 - 0.18 11.8 0.0 0.39 10.7 0.0 1.5 1 0 0 1 1 1 0 L27_2 Na_Ca_ex PF01699.24 EPS31995.1 - 2e-44 151.2 38.0 4.5e-23 81.9 17.2 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein RFamide_26RFa PF11109.8 EPS31995.1 - 0.074 13.6 0.3 0.26 11.8 0.2 2.0 2 0 0 2 2 2 0 Orexigenic neuropeptide Qrfp/P518 TauD PF02668.16 EPS31996.1 - 1.2e-30 107.2 0.0 1.6e-30 106.8 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family ArfGap PF01412.18 EPS31999.1 - 0.48 10.5 3.6 1.2 9.2 3.6 1.6 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf zf-B_box PF00643.24 EPS31999.1 - 5.2 7.3 8.9 39 4.5 4.6 2.7 2 0 0 2 2 2 0 B-box zinc finger 3HCDH_N PF02737.18 EPS32000.1 - 5.3e-30 104.6 0.0 8.4e-28 97.5 0.0 2.2 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EPS32000.1 - 3.8e-12 46.6 0.0 7.2e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain SGL PF08450.12 EPS32000.1 - 0.0014 18.2 0.2 1.5 8.3 0.0 3.7 1 1 2 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region NAD_Gly3P_dh_N PF01210.23 EPS32000.1 - 0.04 13.9 0.0 0.093 12.7 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.15 EPS32000.1 - 0.17 12.1 0.0 1.2 9.3 0.0 2.3 3 0 0 3 3 3 0 NAD binding domain of 6-phosphogluconate dehydrogenase Ldl_recept_b PF00058.17 EPS32000.1 - 0.27 11.7 1.1 29 5.2 0.0 3.7 4 0 0 4 4 4 0 Low-density lipoprotein receptor repeat class B Fungal_trans PF04082.18 EPS32003.1 - 6.1e-19 68.1 0.0 1.3e-18 67.0 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS32003.1 - 8.6e-05 22.6 7.8 0.00016 21.7 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ANAPC2 PF08672.11 EPS32004.1 - 2.4e-23 82.4 0.2 9.9e-23 80.4 0.0 2.2 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 Cullin PF00888.22 EPS32004.1 - 9.2e-23 80.7 0.0 1.9e-22 79.7 0.0 1.4 1 0 0 1 1 1 1 Cullin family SpdB PF05122.13 EPS32005.1 - 0.0019 18.3 0.0 0.0032 17.6 0.0 1.4 1 0 0 1 1 1 1 Mobile element transfer protein Pkr1 PF08636.10 EPS32006.1 - 4.7e-30 103.5 4.5 6.6e-30 103.1 4.5 1.2 1 0 0 1 1 1 1 ER protein Pkr1 OAD_gamma PF04277.13 EPS32006.1 - 0.061 13.9 0.5 0.12 13.0 0.5 1.6 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain SHR3_chaperone PF08229.11 EPS32006.1 - 2 7.3 6.2 0.69 8.9 1.2 2.0 1 1 1 2 2 2 0 ER membrane protein SH3 F-box-like PF12937.7 EPS32007.1 - 0.00019 21.3 1.3 0.00038 20.3 0.3 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EPS32007.1 - 0.099 12.6 0.1 0.3 11.0 0.1 1.8 1 0 0 1 1 1 0 F-box domain F-box-like_2 PF13013.6 EPS32007.1 - 0.11 12.4 0.1 0.34 10.9 0.1 1.8 1 0 0 1 1 1 0 F-box-like domain Glyco_hydro_15 PF00723.21 EPS32008.1 - 5.7e-51 173.7 0.0 7.9e-49 166.6 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 TPT PF03151.16 EPS32009.1 - 5.5e-22 78.4 15.8 7.5e-22 78.0 15.8 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EPS32009.1 - 2.6e-05 24.4 35.0 0.0064 16.7 13.3 2.3 2 0 0 2 2 2 2 EamA-like transporter family PGA2 PF07543.12 EPS32009.1 - 0.4 10.7 4.8 0.78 9.7 4.8 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 AP_endonuc_2 PF01261.24 EPS32010.1 - 3.1e-29 101.9 0.0 5.2e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Spore_III_AB PF09548.10 EPS32010.1 - 0.0064 16.6 2.4 1 9.4 2.3 2.5 2 0 0 2 2 2 2 Stage III sporulation protein AB (spore_III_AB) Mad3_BUB1_I PF08311.12 EPS32011.1 - 4e-45 152.8 0.1 3.6e-44 149.7 0.0 2.2 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.11 EPS32011.1 - 1.1e-10 41.6 0.0 1.9e-09 37.5 0.0 2.9 3 0 0 3 3 3 1 Mad3/BUB1 homology region 2 Pkinase PF00069.25 EPS32011.1 - 9.2e-10 38.3 0.0 3.1e-08 33.3 0.0 2.7 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS32011.1 - 0.0055 16.0 0.0 0.017 14.5 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Mad3_BUB1_I_2 PF17014.5 EPS32011.1 - 0.063 13.4 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein p450 PF00067.22 EPS32013.1 - 4.3e-40 137.8 0.0 5.6e-40 137.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_C15 PF01470.17 EPS32015.1 - 3.7e-10 40.3 0.0 0.00034 20.8 0.0 3.0 2 1 0 2 2 2 2 Pyroglutamyl peptidase MOSC PF03473.17 EPS32016.1 - 6.6e-29 100.6 0.0 1.1e-28 99.9 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 EPS32016.1 - 7.7e-24 83.9 0.0 6.7e-23 80.8 0.0 2.1 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain DNA_pol_phi PF04931.13 EPS32017.1 - 3.7e-259 862.0 20.1 4.5e-259 861.7 20.1 1.1 1 0 0 1 1 1 1 DNA polymerase phi Rad4 PF03835.15 EPS32017.1 - 0.017 14.8 0.2 0.088 12.5 0.2 2.2 2 0 0 2 2 2 0 Rad4 transglutaminase-like domain HTH_micro PF17007.5 EPS32017.1 - 0.048 12.5 0.1 0.11 11.2 0.0 1.6 2 0 0 2 2 2 0 HTH-like SDA1 PF05285.12 EPS32017.1 - 4.9 6.5 37.4 0.026 13.9 25.8 2.5 2 0 0 2 2 2 0 SDA1 XRCC4 PF06632.12 EPS32019.1 - 0.12 11.2 0.7 0.15 10.8 0.7 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 VHP PF02209.19 EPS32022.1 - 2.8 8.1 7.0 4.1 7.6 7.0 1.3 1 0 0 1 1 1 0 Villin headpiece domain Rhodanese PF00581.20 EPS32023.1 - 1.5e-12 47.9 0.0 3.4e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Corona_S2 PF01601.16 EPS32025.1 - 1.8 7.0 14.1 2.4 6.5 14.1 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein CwfJ_C_1 PF04677.15 EPS32026.1 - 2.9e-24 85.3 0.0 5.2e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 EPS32026.1 - 1.3e-14 54.9 0.1 2.7e-14 53.8 0.1 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 DRIM PF07539.12 EPS32027.1 - 2.3e-199 663.8 8.5 9.8e-199 661.7 0.3 4.1 4 0 0 4 4 4 1 Down-regulated in metastasis HEAT PF02985.22 EPS32027.1 - 6.9e-06 25.9 2.5 0.075 13.3 0.0 7.4 9 0 0 9 9 9 1 HEAT repeat BP28CT PF08146.12 EPS32027.1 - 0.0058 16.5 0.4 0.27 11.1 0.0 3.5 3 0 0 3 3 3 1 BP28CT (NUC211) domain Tti2 PF10521.9 EPS32027.1 - 0.019 14.5 0.3 1.6 8.2 0.0 4.0 4 0 0 4 4 4 0 Tti2 family ADH_zinc_N PF00107.26 EPS32027.1 - 0.2 11.6 0.0 0.87 9.6 0.0 2.0 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 EPS32028.1 - 7.1e-11 42.7 0.0 1.6e-10 41.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPS32028.1 - 4.4e-10 39.5 0.0 7.1e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPS32028.1 - 4.6e-08 33.1 0.0 6.9e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPS32028.1 - 4.9e-08 33.6 0.0 8.8e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS32028.1 - 9.6e-07 29.4 0.0 1.7e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPS32028.1 - 0.0086 15.4 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.11 EPS32028.1 - 0.016 14.8 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_4 PF02390.17 EPS32028.1 - 0.1 12.1 0.0 0.27 10.7 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase zf-DNL PF05180.12 EPS32029.1 - 1.3e-28 98.7 0.3 1.9e-28 98.1 0.3 1.3 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.13 EPS32029.1 - 0.00018 21.1 0.8 0.00033 20.3 0.8 1.4 1 0 0 1 1 1 1 CSL zinc finger Elf1 PF05129.13 EPS32029.1 - 0.016 15.3 0.7 0.028 14.5 0.7 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like DUF2039 PF10217.9 EPS32029.1 - 0.021 15.1 0.6 0.034 14.5 0.6 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) RNHCP PF12647.7 EPS32029.1 - 0.036 14.0 0.2 0.036 14.0 0.2 1.9 1 1 1 2 2 2 0 RNHCP domain HypA PF01155.19 EPS32029.1 - 0.09 12.8 0.8 0.14 12.2 0.8 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TFIIS_C PF01096.18 EPS32029.1 - 0.095 12.6 2.6 7 6.6 0.3 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) E7 PF00527.18 EPS32029.1 - 4.1 7.7 6.7 17 5.7 5.8 2.3 2 1 0 2 2 2 0 E7 protein, Early protein Cullin PF00888.22 EPS32030.1 - 5e-198 659.6 10.1 7.3e-198 659.1 10.1 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EPS32030.1 - 1.6e-25 88.9 1.3 1.6e-25 88.9 1.3 2.4 3 0 0 3 3 3 1 Cullin protein neddylation domain SLD5_C PF16922.5 EPS32031.1 - 7.8e-16 58.0 1.7 1.2e-15 57.4 1.7 1.3 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 EPS32031.1 - 2.4e-09 37.6 0.4 3.5e-09 37.1 0.4 1.3 1 0 0 1 1 1 1 GINS complex protein RCR PF12273.8 EPS32032.1 - 9.8e-23 81.1 10.3 1.2e-22 80.8 10.3 1.1 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Hum_adeno_E3A PF05393.11 EPS32032.1 - 0.045 13.7 0.0 0.071 13.1 0.0 1.2 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein Arf PF00025.21 EPS32033.1 - 2.2e-43 147.8 0.0 2.6e-43 147.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EPS32033.1 - 6.3e-19 68.1 0.0 7.2e-19 68.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EPS32033.1 - 2.7e-15 56.7 0.0 3.9e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EPS32033.1 - 2.9e-08 33.8 0.0 4.6e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EPS32033.1 - 6.2e-07 29.0 0.0 7.8e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EPS32033.1 - 4.6e-06 26.2 0.0 5.4e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EPS32033.1 - 0.00017 20.9 0.1 0.00094 18.4 0.0 2.2 1 1 1 2 2 2 1 G-protein alpha subunit Dynamin_N PF00350.23 EPS32033.1 - 0.0064 16.6 0.1 0.055 13.5 0.1 2.0 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.18 EPS32033.1 - 0.0097 15.4 0.5 0.058 12.9 0.5 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EPS32033.1 - 0.033 14.1 0.0 8 6.3 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1_Xtn PF16897.5 EPS32033.1 - 0.037 14.1 0.0 0.065 13.3 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain RNA_pol_Rpb2_6 PF00562.28 EPS32035.1 - 8.4e-116 387.2 0.1 1.2e-115 386.8 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EPS32035.1 - 3.5e-37 127.9 0.0 5.4e-37 127.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 EPS32035.1 - 1.5e-27 95.6 0.4 3.6e-27 94.3 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 EPS32035.1 - 2.9e-25 88.0 0.0 5.5e-25 87.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 EPS32035.1 - 2.6e-23 82.6 0.0 4.7e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 EPS32035.1 - 9.3e-16 58.0 0.0 1.8e-14 53.9 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 APH PF01636.23 EPS32037.1 - 1.1e-08 35.3 0.3 2.5e-08 34.1 0.1 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family ASXH PF13919.6 EPS32037.1 - 0.053 13.5 0.1 0.09 12.8 0.1 1.5 1 1 0 1 1 1 0 Asx homology domain Proteasome PF00227.26 EPS32038.1 - 2.2e-42 144.7 0.5 4.1e-33 114.5 0.1 2.0 2 0 0 2 2 2 2 Proteasome subunit Pil1 PF13805.6 EPS32039.1 - 2.9e-93 312.2 6.9 3.3e-93 312.0 6.9 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 SWI-SNF_Ssr4 PF08549.10 EPS32040.1 - 1.3e-235 784.4 28.6 7.7e-218 725.7 5.4 3.0 1 1 2 3 3 3 3 Fungal domain of unknown function (DUF1750) Fungal_trans PF04082.18 EPS32042.1 - 7.3e-29 100.6 0.0 1.1e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS32042.1 - 1.6e-07 31.3 7.2 2.8e-07 30.5 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 EPS32043.1 - 2.5e-27 95.8 81.3 1.2e-26 93.5 54.6 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2208 PF09973.9 EPS32043.1 - 1.2 8.8 4.5 2.4 7.7 4.5 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) ADH_zinc_N PF00107.26 EPS32044.1 - 1.1e-06 28.7 0.0 1.6e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPS32044.1 - 2.4e-06 27.4 0.0 4.7e-05 23.2 0.0 2.6 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EPS32044.1 - 0.00051 21.1 0.0 0.0011 20.0 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PALP PF00291.25 EPS32044.1 - 0.062 12.7 0.2 0.086 12.2 0.2 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme Sacchrp_dh_NADP PF03435.18 EPS32044.1 - 0.12 12.6 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain AMP-binding PF00501.28 EPS32046.1 - 7.8e-155 515.6 0.1 2.8e-89 299.6 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.20 EPS32046.1 - 1.6e-98 330.4 0.1 3e-39 135.0 0.0 3.6 3 1 0 3 3 3 3 Condensation domain PP-binding PF00550.25 EPS32046.1 - 3.5e-16 59.3 0.4 7.4e-07 29.4 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EPS32046.1 - 1.3e-14 54.9 0.1 4e-07 30.9 0.0 3.2 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain RuBisCO_large_N PF02788.16 EPS32046.1 - 0.075 13.2 0.2 0.32 11.2 0.1 2.1 2 0 0 2 2 2 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain MFS_1 PF07690.16 EPS32047.1 - 1.4e-34 119.6 26.2 1.4e-34 119.6 26.2 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Trp_oprn_chp PF09534.10 EPS32047.1 - 0.15 11.8 2.2 0.18 11.6 0.2 1.9 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) FUSC_2 PF13515.6 EPS32048.1 - 4e-24 85.1 8.6 4e-24 85.1 8.6 2.6 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 EPS32048.1 - 1.8e-07 30.4 3.8 0.00028 19.8 0.9 3.7 3 0 0 3 3 3 2 Aluminium activated malate transporter ArAE_2 PF10334.9 EPS32048.1 - 3.3e-05 23.8 0.1 0.00013 21.9 0.1 2.0 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC PF04632.12 EPS32048.1 - 0.0016 17.1 1.6 0.0016 17.1 1.6 4.3 4 1 1 5 5 5 3 Fusaric acid resistance protein family Melittin PF01372.17 EPS32048.1 - 0.047 13.6 0.1 0.38 10.8 0.0 2.7 2 0 0 2 2 2 0 Melittin Phage_holin_Dp1 PF16938.5 EPS32048.1 - 0.35 11.1 4.5 0.37 11.1 0.3 2.7 2 1 1 3 3 3 0 Putative phage holin Dp-1 ArAE_2_N PF10337.9 EPS32048.1 - 1.5 7.8 7.0 0.091 11.8 0.2 2.2 2 0 0 2 2 2 0 Putative ER transporter, 6TM, N-terminal Thi4 PF01946.17 EPS32049.1 - 9.8e-111 368.6 0.0 1.2e-110 368.4 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EPS32049.1 - 5.3e-08 32.8 0.3 1.9e-07 31.0 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EPS32049.1 - 7.2e-06 26.1 0.4 2.7e-05 24.3 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EPS32049.1 - 7.2e-05 22.0 0.1 0.00012 21.2 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EPS32049.1 - 0.00046 19.4 1.6 0.018 14.2 0.7 2.2 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 EPS32049.1 - 0.0022 17.3 0.0 0.0031 16.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EPS32049.1 - 0.0032 17.5 0.4 0.0074 16.3 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 EPS32049.1 - 0.0061 15.9 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EPS32049.1 - 0.044 13.0 0.0 0.069 12.4 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EPS32049.1 - 0.045 13.1 0.0 0.058 12.7 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EPS32049.1 - 0.061 12.0 0.1 0.23 10.1 0.4 1.7 2 0 0 2 2 2 0 HI0933-like protein Exo_endo_phos PF03372.23 EPS32050.1 - 8.5e-14 51.6 0.0 1.3e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.32 EPS32051.1 - 1.2e-47 158.8 20.2 2.9e-12 46.9 0.3 7.6 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS32051.1 - 4.6e-16 58.9 0.2 0.00023 21.4 0.0 5.7 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EPS32051.1 - 3.2e-08 33.7 0.1 0.0021 18.0 0.0 2.9 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EPS32051.1 - 2.4e-05 23.8 0.0 0.03 13.7 0.0 3.3 2 2 1 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 EPS32051.1 - 2.4e-05 23.5 0.1 0.12 11.3 0.0 4.2 1 1 4 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EPS32051.1 - 3.1e-05 22.9 9.9 0.11 11.1 0.1 5.1 3 2 3 6 6 6 3 Nucleoporin Nup120/160 PD40 PF07676.12 EPS32051.1 - 0.00012 21.9 0.0 0.05 13.6 0.0 3.2 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat VID27 PF08553.10 EPS32051.1 - 0.1 11.6 0.0 0.61 9.1 0.0 2.2 1 1 2 3 3 3 0 VID27 C-terminal WD40-like domain Glyco_hydro_cc PF11790.8 EPS32052.1 - 6.9e-66 222.2 0.7 8e-66 222.0 0.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Choline_transpo PF04515.12 EPS32052.1 - 0.049 12.8 0.0 0.091 11.9 0.0 1.3 1 0 0 1 1 1 0 Plasma-membrane choline transporter NAGidase PF07555.13 EPS32054.1 - 1.2e-101 339.9 0.1 2.2e-101 339.1 0.1 1.4 1 0 0 1 1 1 1 beta-N-acetylglucosaminidase Glyco_hydro_20b PF02838.15 EPS32054.1 - 7.7e-17 62.2 0.3 1.5e-16 61.3 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_67N PF03648.14 EPS32054.1 - 0.0011 19.3 0.1 0.0026 18.0 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Aminotran_5 PF00266.19 EPS32061.1 - 7.6e-30 104.1 0.0 9.8e-30 103.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.19 EPS32061.1 - 0.026 14.6 0.1 0.084 12.9 0.0 1.9 2 0 0 2 2 2 0 B12 binding domain GGDEF PF00990.21 EPS32061.1 - 0.21 11.3 0.2 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 Diguanylate cyclase, GGDEF domain Metallophos_2 PF12850.7 EPS32062.1 - 2.2e-13 50.7 0.0 2.7e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RRM_1 PF00076.22 EPS32063.1 - 2.9e-16 59.0 0.0 4.8e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EPS32063.1 - 0.014 15.4 0.0 0.023 14.7 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif BLOC1_2 PF10046.9 EPS32063.1 - 0.032 14.5 1.3 0.05 13.9 1.3 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Med9 PF07544.13 EPS32063.1 - 0.047 13.8 0.8 0.077 13.1 0.8 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 GAS PF13851.6 EPS32063.1 - 0.055 12.8 2.0 0.075 12.4 2.0 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF3450 PF11932.8 EPS32063.1 - 0.084 12.2 3.9 0.11 11.7 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF724 PF05266.14 EPS32063.1 - 0.13 12.1 2.1 0.17 11.7 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Wtap PF17098.5 EPS32063.1 - 0.16 11.9 3.2 0.22 11.4 3.2 1.2 1 0 0 1 1 1 0 WTAP/Mum2p family Spc7 PF08317.11 EPS32063.1 - 0.17 10.7 3.5 0.22 10.3 3.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein GPS2_interact PF15784.5 EPS32063.1 - 0.21 12.0 2.6 0.33 11.4 2.6 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor 2-interacting domain DivIC PF04977.15 EPS32063.1 - 0.38 10.5 4.2 0.76 9.6 4.2 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF4337 PF14235.6 EPS32063.1 - 0.61 10.2 2.6 0.84 9.7 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) ZapB PF06005.12 EPS32063.1 - 1.1 9.8 8.3 0.58 10.6 5.6 1.8 2 0 0 2 2 2 0 Cell division protein ZapB Troponin PF00992.20 EPS32063.1 - 1.6 9.0 7.4 2.4 8.5 7.4 1.2 1 0 0 1 1 1 0 Troponin HECT PF00632.25 EPS32065.1 - 2.1e-96 323.0 0.0 2.9e-96 322.6 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 EPS32065.1 - 5.5e-32 109.5 25.3 8.7e-12 44.9 2.6 4.6 5 0 0 5 5 5 3 WW domain C2 PF00168.30 EPS32065.1 - 2.7e-18 66.1 0.0 7.2e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 C2 domain Rrn6 PF10214.9 EPS32065.1 - 0.08 11.4 12.4 0.12 10.9 12.4 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor IBR PF01485.21 EPS32066.1 - 2.9e-07 30.6 26.1 3.4e-05 24.0 2.7 4.7 4 2 0 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 EPS32066.1 - 2.7e-05 23.9 7.8 2.7e-05 23.9 7.8 4.5 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPS32066.1 - 0.0028 17.5 10.8 0.0028 17.5 10.8 4.3 4 1 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPS32066.1 - 0.014 15.4 13.5 0.014 15.4 13.5 3.6 4 0 0 4 4 4 0 RING-type zinc-finger zf-RING_5 PF14634.6 EPS32066.1 - 0.014 15.3 12.8 0.014 15.3 12.8 5.0 4 2 0 4 4 4 0 zinc-RING finger domain NEMP PF10225.9 EPS32066.1 - 0.14 11.8 0.5 1.3 8.7 0.1 2.3 3 0 0 3 3 3 0 NEMP family zf-C3HC4_3 PF13920.6 EPS32066.1 - 2.9 7.8 58.6 0.15 12.0 9.2 4.7 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) HD PF01966.22 EPS32067.1 - 0.0001 22.5 0.2 0.00016 21.9 0.2 1.4 1 0 0 1 1 1 1 HD domain Response_reg PF00072.24 EPS32068.1 - 4.4e-22 78.4 0.1 9.5e-22 77.3 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 EPS32068.1 - 2.9e-19 69.6 0.0 5.7e-19 68.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EPS32068.1 - 4.3e-11 42.7 0.1 1.6e-10 40.9 0.1 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 EPS32068.1 - 0.014 15.7 0.0 0.067 13.5 0.0 2.2 2 0 0 2 2 2 0 GAF domain GAF_3 PF13492.6 EPS32068.1 - 0.15 12.4 0.0 1.7 9.0 0.0 2.8 3 0 0 3 3 3 0 GAF domain Zn_clus PF00172.18 EPS32070.1 - 1.5e-08 34.6 9.4 3e-08 33.6 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EPS32070.1 - 8.9e-08 31.3 0.9 2.1e-07 30.1 0.9 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Atg14 PF10186.9 EPS32071.1 - 0.0012 18.0 8.1 0.0015 17.7 8.1 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Golgin_A5 PF09787.9 EPS32071.1 - 0.0052 16.3 10.9 0.0081 15.7 10.9 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 DUF724 PF05266.14 EPS32071.1 - 0.0055 16.6 13.3 0.0097 15.8 13.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF724) LMBR1 PF04791.16 EPS32071.1 - 0.0061 15.5 2.2 0.0072 15.3 2.2 1.2 1 0 0 1 1 1 1 LMBR1-like membrane protein DUF3450 PF11932.8 EPS32071.1 - 0.025 13.9 9.2 0.04 13.2 9.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Erf4 PF10256.9 EPS32071.1 - 0.026 14.6 0.0 0.19 11.8 0.0 2.1 2 0 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family TMPIT PF07851.13 EPS32071.1 - 0.045 13.0 7.5 0.065 12.5 7.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein APG6_N PF17675.1 EPS32071.1 - 0.05 14.1 16.9 0.13 12.8 16.0 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region HAUS-augmin3 PF14932.6 EPS32071.1 - 0.083 12.5 10.0 0.13 11.8 10.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 MbeD_MobD PF04899.12 EPS32071.1 - 0.098 12.8 2.2 14 5.9 0.1 2.8 3 0 0 3 3 2 0 MbeD/MobD like FapA PF03961.13 EPS32071.1 - 0.1 11.2 8.8 0.17 10.4 8.8 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A Phage_GPO PF05929.11 EPS32071.1 - 0.12 12.0 4.1 0.17 11.5 4.1 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Thiolase_C PF02803.18 EPS32071.1 - 0.14 11.9 0.3 0.31 10.7 0.2 1.5 1 1 0 1 1 1 0 Thiolase, C-terminal domain Laminin_II PF06009.12 EPS32071.1 - 0.14 12.1 4.6 0.26 11.3 4.6 1.4 1 0 0 1 1 1 0 Laminin Domain II Spt5_N PF11942.8 EPS32071.1 - 0.2 12.7 11.7 0.36 11.9 10.8 1.8 2 0 0 2 2 1 0 Spt5 transcription elongation factor, acidic N-terminal Nup88 PF10168.9 EPS32071.1 - 0.2 9.4 15.1 0.27 9.0 15.1 1.1 1 0 0 1 1 1 0 Nuclear pore component OmpH PF03938.14 EPS32071.1 - 0.27 11.6 15.5 0.54 10.6 15.5 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) FUSC PF04632.12 EPS32071.1 - 0.56 8.7 2.1 0.66 8.4 2.1 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family UPF0242 PF06785.11 EPS32071.1 - 0.58 10.2 16.1 0.88 9.6 16.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Exonuc_VII_L PF02601.15 EPS32071.1 - 0.59 9.7 4.8 0.71 9.4 4.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 EPS32071.1 - 0.66 7.8 5.1 0.83 7.5 5.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prominin PF05478.11 EPS32071.1 - 0.81 7.6 3.5 1.1 7.2 3.5 1.1 1 0 0 1 1 1 0 Prominin ADIP PF11559.8 EPS32071.1 - 0.85 9.7 21.1 1.3 9.1 21.1 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding TssO PF17561.2 EPS32071.1 - 0.85 9.7 7.6 0.76 9.9 4.7 2.2 2 1 1 3 3 2 0 Type VI secretion system, TssO DUF485 PF04341.12 EPS32071.1 - 1.2 9.2 2.5 6.1 6.9 0.1 2.5 2 1 1 3 3 2 0 Protein of unknown function, DUF485 AAA_23 PF13476.6 EPS32071.1 - 1.5 9.3 12.2 0.025 15.1 2.9 2.1 2 0 0 2 2 2 0 AAA domain Rx_N PF18052.1 EPS32071.1 - 2.8 8.3 10.9 9.6 6.6 10.9 1.8 1 1 0 1 1 1 0 Rx N-terminal domain DUF1664 PF07889.12 EPS32071.1 - 3.1 7.9 8.6 1.1 9.3 4.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) YabA PF06156.13 EPS32071.1 - 6.2 7.5 9.4 15 6.2 8.6 2.0 1 1 0 1 1 1 0 Initiation control protein YabA DUF4407 PF14362.6 EPS32071.1 - 7.8 5.8 8.6 14 4.9 8.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Syntaxin_2 PF14523.6 EPS32071.1 - 8.1 6.9 14.6 3.2 8.2 11.9 1.6 2 0 0 2 2 1 0 Syntaxin-like protein SUR7 PF06687.12 EPS32073.1 - 6.8e-39 133.7 11.1 9.5e-39 133.2 11.1 1.2 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 EPS32073.1 - 0.0064 16.4 6.7 0.0064 16.4 6.7 1.9 2 1 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 DUF898 PF05987.13 EPS32073.1 - 0.076 12.1 5.4 0.016 14.3 1.9 1.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF898) HBD PF18534.1 EPS32075.1 - 0.21 11.7 0.0 0.38 10.9 0.0 1.4 1 0 0 1 1 1 0 Helical bundle domain Lactamase_B_2 PF12706.7 EPS32076.1 - 3.1e-16 59.5 1.0 4.3e-15 55.8 0.8 2.1 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EPS32076.1 - 1.3e-14 54.4 0.3 3.4e-14 53.0 0.3 1.7 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DUF3898 PF13037.6 EPS32076.1 - 0.066 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3898) MDMPI_C PF07398.11 EPS32076.1 - 0.081 13.8 0.0 0.5 11.3 0.0 2.3 1 1 1 2 2 2 0 MDMPI C-terminal domain DUF4399 PF14347.6 EPS32076.1 - 0.13 12.6 0.5 0.34 11.3 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4399) Lactamase_B PF00753.27 EPS32076.1 - 0.17 11.8 6.9 0.49 10.4 4.5 2.7 1 1 1 2 2 2 0 Metallo-beta-lactamase superfamily Tctex-1 PF03645.13 EPS32077.1 - 4e-35 120.2 0.0 4.7e-35 119.9 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family NLE PF08154.12 EPS32077.1 - 0.083 13.4 0.0 0.14 12.7 0.0 1.3 1 0 0 1 1 1 0 NLE (NUC135) domain WD40 PF00400.32 EPS32078.1 - 6e-42 140.8 18.4 3.3e-10 40.4 0.1 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS32078.1 - 2.6e-11 43.7 0.5 0.33 11.3 0.0 4.9 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EPS32078.1 - 5.7e-08 31.9 2.8 0.031 12.9 0.1 4.1 3 2 1 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EPS32078.1 - 0.0001 21.4 0.3 3.4 6.5 0.0 4.3 4 1 0 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 EPS32078.1 - 0.00058 18.9 1.4 0.0014 17.6 0.1 2.3 3 1 0 3 3 3 1 Partner and localizer of BRCA2 WD40 domain eIF2A PF08662.11 EPS32078.1 - 0.0012 18.8 0.3 0.047 13.6 0.0 2.9 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Hira PF07569.11 EPS32078.1 - 0.011 15.5 2.2 5.2 6.7 0.1 3.8 4 1 0 4 4 4 0 TUP1-like enhancer of split HPS3_N PF14761.6 EPS32078.1 - 0.024 14.2 0.0 0.14 11.7 0.0 2.2 2 1 0 2 2 2 0 Hermansky-Pudlak syndrome 3 Coatomer_WDAD PF04053.14 EPS32078.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Coatomer WD associated region Rootletin PF15035.6 EPS32079.1 - 0.0033 17.5 0.6 0.006 16.6 0.6 1.4 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion APG6_N PF17675.1 EPS32079.1 - 0.0087 16.6 2.9 0.016 15.8 2.9 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region BRE1 PF08647.11 EPS32079.1 - 0.041 14.0 1.4 0.047 13.8 0.1 1.7 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase GAS PF13851.6 EPS32079.1 - 0.081 12.3 7.5 0.3 10.4 7.5 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Helo_like_N PF17111.5 EPS32079.1 - 0.1 11.9 0.0 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins Exonuc_VII_L PF02601.15 EPS32079.1 - 0.24 10.9 3.7 0.46 10.0 3.7 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-F_leu_zip PF10473.9 EPS32079.1 - 0.32 11.0 6.1 1.1 9.3 0.7 2.2 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 EPS32079.1 - 0.66 9.5 7.1 1.5 8.3 3.8 2.0 1 1 1 2 2 2 0 Intermediate filament protein DUF4201 PF13870.6 EPS32079.1 - 1.1 8.9 10.0 12 5.6 1.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Acetyltransf_1 PF00583.25 EPS32080.1 - 5e-11 42.9 0.0 7.2e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EPS32080.1 - 9.8e-08 31.9 0.1 1.7e-07 31.1 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 EPS32080.1 - 2.6e-07 30.6 0.3 3.8e-07 30.1 0.3 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EPS32080.1 - 5.1e-05 23.6 0.0 8.7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EPS32080.1 - 0.0079 16.3 0.3 0.012 15.6 0.3 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF4646 PF15496.6 EPS32081.1 - 0.013 16.1 3.0 0.17 12.5 0.8 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4646) adh_short PF00106.25 EPS32083.1 - 4.2e-13 49.2 0.0 8.4e-09 35.2 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EPS32083.1 - 2.7e-09 36.9 0.0 1.7e-07 31.0 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPS32083.1 - 0.0012 18.7 0.0 0.0017 18.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Gpr1_Fun34_YaaH PF01184.19 EPS32084.1 - 2.5e-17 63.2 22.2 2.6e-15 56.6 9.0 3.1 1 1 2 3 3 3 3 GPR1/FUN34/yaaH family Mod_r PF07200.13 EPS32085.1 - 3.1e-24 85.7 7.6 3.1e-24 85.7 7.6 1.4 2 0 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein Shugoshin_N PF07558.11 EPS32085.1 - 0.0084 16.0 1.6 0.017 15.0 1.6 1.4 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Fib_alpha PF08702.10 EPS32085.1 - 0.14 12.4 0.6 0.33 11.2 0.6 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family PSK_trans_fac PF07704.11 EPS32085.1 - 0.9 10.3 7.6 1 10.2 2.9 2.4 2 0 0 2 2 2 0 Rv0623-like transcription factor ATG16 PF08614.11 EPS32085.1 - 1.4 9.1 17.1 0.081 13.1 10.0 2.4 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF1690 PF07956.11 EPS32085.1 - 5.1 7.5 8.0 2.3 8.6 2.8 2.2 1 1 0 2 2 2 0 Protein of Unknown function (DUF1690) Ank_5 PF13857.6 EPS32087.1 - 9.3e-10 38.6 0.4 3.2e-09 36.8 0.2 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EPS32087.1 - 1.6e-07 31.8 0.5 2.9e-07 31.0 0.2 1.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPS32087.1 - 3.3e-07 30.7 0.0 3e-06 27.7 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPS32087.1 - 2.4e-06 27.4 1.4 5.1e-05 23.3 0.1 3.3 3 1 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 EPS32087.1 - 8.4e-05 22.8 0.7 0.0035 17.7 0.2 3.1 3 1 0 3 3 3 1 Ankyrin repeat YejG PF13989.6 EPS32087.1 - 0.032 14.7 0.0 0.055 13.9 0.0 1.4 1 0 0 1 1 1 0 YejG-like protein tRNA_lig_CPD PF08302.11 EPS32088.1 - 1.6e-91 306.3 0.0 2.4e-91 305.7 0.0 1.3 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.10 EPS32088.1 - 2.4e-86 289.1 0.2 4.3e-86 288.3 0.2 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 EPS32088.1 - 1.7e-48 164.9 0.0 2.9e-48 164.1 0.0 1.4 1 0 0 1 1 1 1 tRNA ligase kinase domain RNA_ligase PF09414.10 EPS32088.1 - 0.00072 19.9 0.2 0.0016 18.7 0.2 1.6 1 0 0 1 1 1 1 RNA ligase Got1 PF04178.12 EPS32089.1 - 1.4e-35 122.1 13.8 1.8e-35 121.7 13.8 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF2070 PF09843.9 EPS32089.1 - 3.1 6.0 4.9 3.8 5.7 4.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) WD40 PF00400.32 EPS32092.1 - 0.079 13.9 0.6 0.16 12.9 0.2 1.8 2 0 0 2 2 2 0 WD domain, G-beta repeat HLH PF00010.26 EPS32094.1 - 6.4e-13 48.4 0.0 4.5e-12 45.7 0.0 2.4 3 1 0 3 3 3 1 Helix-loop-helix DNA-binding domain Cwf_Cwc_15 PF04889.12 EPS32095.1 - 0.034 13.9 10.6 0.055 13.2 10.6 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein APH PF01636.23 EPS32096.1 - 1.4e-16 61.2 0.0 3.1e-16 60.1 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPS32096.1 - 0.0013 18.4 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase AIP3 PF03915.13 EPS32098.1 - 1.1e-155 518.8 7.1 1.9e-155 518.0 7.1 1.4 1 0 0 1 1 1 1 Actin interacting protein 3 Lectin_N PF03954.14 EPS32098.1 - 0.00012 21.9 0.5 0.00047 19.9 0.5 2.0 1 0 0 1 1 1 1 Hepatic lectin, N-terminal domain RasGAP_C PF03836.15 EPS32098.1 - 0.019 15.1 0.4 0.5 10.5 0.3 3.3 3 1 1 4 4 4 0 RasGAP C-terminus LsmAD PF06741.13 EPS32100.1 - 1.6e-27 95.8 2.3 1.6e-27 95.8 2.3 1.9 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.6 EPS32100.1 - 1e-20 73.7 0.4 2.2e-20 72.5 0.1 1.8 2 0 0 2 2 2 1 Ataxin 2 SM domain Pkinase PF00069.25 EPS32102.1 - 2.5e-11 43.4 0.0 6.7e-11 42.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Cnd1 PF12717.7 EPS32102.1 - 2.5e-07 30.9 0.0 4.4e-06 26.8 0.0 2.4 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EPS32102.1 - 3.3e-07 30.0 2.8 0.13 12.6 0.0 5.2 5 1 0 5 5 5 2 HEAT repeat Pkinase_Tyr PF07714.17 EPS32102.1 - 2.6e-05 23.6 0.0 4.6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.6 EPS32102.1 - 0.00013 22.3 0.7 0.32 11.4 0.1 3.4 2 1 1 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 EPS32102.1 - 0.00022 21.7 0.7 0.38 11.3 0.5 3.3 2 1 0 2 2 2 2 HEAT-like repeat Kinase-like PF14531.6 EPS32102.1 - 0.007 15.7 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Nitrate_red_del PF02613.15 EPS32102.1 - 0.056 13.5 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Nitrate reductase delta subunit CoA_trans PF01144.23 EPS32102.1 - 0.16 11.4 0.0 0.36 10.2 0.0 1.5 1 0 0 1 1 1 0 Coenzyme A transferase Adaptin_N PF01602.20 EPS32102.1 - 0.23 10.0 0.0 0.88 8.1 0.0 1.7 1 1 0 1 1 1 0 Adaptin N terminal region Aldo_ket_red PF00248.21 EPS32103.1 - 3.1e-46 157.9 0.0 6.2e-46 156.9 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family VIT1 PF01988.19 EPS32104.1 - 1.6e-67 227.5 1.6 1.8e-67 227.3 1.6 1.0 1 0 0 1 1 1 1 VIT family Mid2 PF04478.12 EPS32104.1 - 0.19 11.5 0.0 3.1 7.6 0.0 2.1 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor DUF3959 PF13105.6 EPS32104.1 - 0.4 10.2 2.6 0.62 9.5 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Ferric_reduct PF01794.19 EPS32105.1 - 3.5e-17 62.7 13.4 3.5e-17 62.7 13.4 3.5 3 1 1 4 4 4 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EPS32105.1 - 1.4e-15 57.7 0.0 2.1e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EPS32105.1 - 1.3e-11 44.5 0.0 3.2e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain PDR_assoc PF08370.11 EPS32105.1 - 0.049 13.4 4.3 0.28 11.0 0.3 2.6 2 0 0 2 2 2 0 Plant PDR ABC transporter associated GFA PF04828.14 EPS32106.1 - 7e-07 29.5 0.5 1.3e-06 28.6 0.5 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme CHCH PF06747.13 EPS32107.1 - 2.9e-06 27.2 0.4 4.1e-06 26.8 0.4 1.2 1 0 0 1 1 1 1 CHCH domain COX17 PF05051.13 EPS32107.1 - 0.012 16.0 2.6 2.3 8.6 1.4 2.2 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Pet191_N PF10203.9 EPS32107.1 - 0.057 13.7 2.5 0.22 11.8 2.4 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Nop16 PF09420.10 EPS32107.1 - 0.069 13.2 0.1 0.073 13.1 0.1 1.1 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 CX9C PF16860.5 EPS32107.1 - 0.096 12.7 0.5 0.16 12.0 0.5 1.4 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, NPR3 PF03666.13 EPS32108.1 - 5.6e-155 516.7 0.4 2.4e-154 514.6 0.0 2.0 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 HTH_IclR PF09339.10 EPS32108.1 - 0.12 12.2 1.7 1.3 8.9 0.0 3.1 3 0 0 3 3 3 0 IclR helix-turn-helix domain Mago-bind PF09282.10 EPS32108.1 - 0.16 11.9 4.4 0.18 11.7 2.3 2.2 2 0 0 2 2 2 0 Mago binding La PF05383.17 EPS32109.1 - 4.4e-19 68.3 0.1 7.9e-19 67.5 0.1 1.4 1 0 0 1 1 1 1 La domain Band_7 PF01145.25 EPS32110.1 - 5e-30 104.8 0.5 5e-30 104.8 0.5 1.6 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_C PF16200.5 EPS32110.1 - 5.5e-24 84.0 0.4 5.5e-24 84.0 0.4 2.1 2 0 0 2 2 2 1 C-terminal region of band_7 Pox_A11 PF05061.13 EPS32110.1 - 0.088 12.1 0.2 0.13 11.5 0.2 1.2 1 0 0 1 1 1 0 Poxvirus A11 Protein DRTGG PF07085.12 EPS32110.1 - 0.11 12.3 0.6 2.8 7.8 0.1 2.7 3 0 0 3 3 3 0 DRTGG domain GSH-S_N PF02951.14 EPS32110.1 - 0.13 12.3 0.2 0.57 10.3 0.1 2.1 2 0 0 2 2 2 0 Prokaryotic glutathione synthetase, N-terminal domain Hira PF07569.11 EPS32111.1 - 2.1e-84 282.7 0.0 7.4e-84 280.9 0.0 2.0 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.32 EPS32111.1 - 4.4e-26 90.6 28.6 7.1e-05 23.5 0.0 9.4 8 1 1 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS32111.1 - 1.2e-14 54.4 0.1 0.04 14.2 0.0 6.4 4 1 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 EPS32111.1 - 3.1e-10 39.6 0.1 9.4e-10 38.1 0.1 1.9 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.12 EPS32111.1 - 1.3e-06 28.2 2.0 0.44 10.6 0.0 5.8 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 EPS32111.1 - 0.0023 17.0 1.3 1.8 7.4 0.0 4.2 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 EPS32111.1 - 0.022 12.8 0.0 0.067 11.2 0.0 1.7 2 0 0 2 2 2 0 IKI3 family YchF-GTPase_C PF06071.13 EPS32112.1 - 4.4e-35 119.7 0.2 1.1e-34 118.5 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EPS32112.1 - 2.3e-16 59.9 0.0 5.9e-16 58.6 0.0 1.7 1 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EPS32112.1 - 0.0007 19.1 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 EPS32112.1 - 0.0012 18.8 0.0 0.0034 17.4 0.0 1.8 2 0 0 2 2 2 1 TGS domain AAA_14 PF13173.6 EPS32112.1 - 0.079 13.0 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain PUA PF01472.20 EPS32113.1 - 7.2e-14 51.5 0.3 9.1e-14 51.2 0.3 1.2 1 0 0 1 1 1 1 PUA domain Pre-PUA PF17832.1 EPS32113.1 - 1.2e-05 25.8 0.1 2.2e-05 25.1 0.1 1.4 1 0 0 1 1 1 1 Pre-PUA-like domain RIC1 PF07064.13 EPS32114.1 - 1.2e-83 280.4 0.1 1.8e-83 279.8 0.1 1.3 1 0 0 1 1 1 1 RIC1 SGTA_dimer PF16546.5 EPS32115.1 - 1.1e-25 89.2 0.4 2e-25 88.3 0.4 1.4 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_1 PF00515.28 EPS32115.1 - 6.8e-20 70.0 5.4 1.3e-06 27.9 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EPS32115.1 - 1.8e-17 61.9 5.0 5e-06 26.2 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EPS32115.1 - 4e-12 45.6 6.1 3.6e-09 36.2 1.7 3.2 1 1 2 3 3 3 3 TPR repeat TPR_8 PF13181.6 EPS32115.1 - 6.6e-12 44.6 6.6 9.9e-06 25.4 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EPS32115.1 - 2.2e-07 30.4 0.1 0.083 13.0 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 EPS32115.1 - 2.3e-07 30.7 0.5 0.0053 17.0 0.2 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EPS32115.1 - 2.5e-07 30.9 3.8 0.00034 20.8 0.8 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EPS32115.1 - 3.2e-07 30.9 7.9 0.012 16.3 0.1 2.9 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EPS32115.1 - 3.2e-07 30.6 6.1 0.029 15.2 0.3 3.8 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 EPS32115.1 - 1.2e-06 29.0 2.1 0.00074 20.0 0.7 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 EPS32115.1 - 3.1e-06 27.2 0.8 0.0021 18.1 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat STI1 PF17830.1 EPS32115.1 - 9.7e-05 22.2 8.5 0.0022 17.9 5.3 2.5 2 0 0 2 2 2 1 STI1 domain TPR_6 PF13174.6 EPS32115.1 - 0.0012 19.3 5.4 0.31 11.8 0.2 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat XPC-binding PF09280.11 EPS32115.1 - 0.0035 17.0 1.1 0.01 15.5 1.1 1.8 1 0 0 1 1 1 1 XPC-binding domain TPR_15 PF13429.6 EPS32115.1 - 0.0054 16.0 0.3 0.0083 15.4 0.3 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 EPS32115.1 - 0.013 15.3 6.8 2.8 8.0 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 EPS32115.1 - 0.015 15.7 1.4 0.1 13.1 0.3 2.2 2 0 0 2 2 2 0 Bacterial transcriptional activator domain GAGE PF05831.11 EPS32115.1 - 0.073 13.6 4.7 0.97 10.0 0.2 2.5 2 0 0 2 2 2 0 GAGE protein MIT PF04212.18 EPS32115.1 - 0.12 12.5 2.0 3.5 7.8 0.3 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain DUF1860 PF08949.10 EPS32115.1 - 3.2 7.4 9.4 4.4 7.0 2.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1860) Tim44 PF04280.15 EPS32116.1 - 2.7e-35 121.6 0.1 1.3e-34 119.4 0.0 2.0 2 0 0 2 2 2 1 Tim44-like domain KIF1B PF12423.8 EPS32116.1 - 0.028 14.8 1.5 0.053 14.0 0.0 2.3 2 0 0 2 2 2 0 Kinesin protein 1B Sporozoite_P67 PF05642.11 EPS32116.1 - 0.053 11.6 6.1 0.077 11.1 6.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ribosomal_S11 PF00411.19 EPS32117.1 - 1.6e-07 31.7 0.0 3e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S11 VPS9 PF02204.18 EPS32118.1 - 2.2e-17 63.2 0.0 5.3e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.6 EPS32118.1 - 9.3e-15 54.5 0.0 1.3e-12 47.7 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EPS32118.1 - 1.1e-12 48.4 0.0 0.00049 20.6 0.0 3.8 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) PX PF00787.24 EPS32118.1 - 3.6e-07 30.1 0.6 9.5e-07 28.8 0.3 1.9 2 0 0 2 2 2 1 PX domain Ank_4 PF13637.6 EPS32118.1 - 8.4e-07 29.4 0.0 0.012 16.2 0.0 4.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EPS32118.1 - 0.00015 22.0 0.1 0.8 10.3 0.1 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 EPS32118.1 - 0.021 15.3 0.1 25 5.9 0.0 5.0 5 0 0 5 5 5 0 Ankyrin repeat Inhibitor_I78 PF11720.8 EPS32120.1 - 2.5e-10 40.3 0.0 2.9e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.18 EPS32120.1 - 0.012 16.3 0.2 0.016 15.9 0.2 1.4 1 1 0 1 1 1 0 Potato inhibitor I family Alpha-L-AF_C PF06964.12 EPS32121.1 - 2e-29 102.9 0.0 2.9e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain Sugar_tr PF00083.24 EPS32122.1 - 2.3e-104 349.8 23.5 2.6e-104 349.6 23.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS32122.1 - 1.6e-28 99.7 29.0 2.6e-21 76.0 11.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2838 PF10998.8 EPS32122.1 - 0.2 11.9 5.9 1.9 8.7 1.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2838) LapA_dom PF06305.11 EPS32122.1 - 4.3 7.2 9.0 6 6.8 0.3 4.2 3 1 1 4 4 4 0 Lipopolysaccharide assembly protein A domain Nefa_Nip30_N PF10187.9 EPS32123.1 - 1e-31 109.4 16.4 1e-31 109.4 16.4 2.2 2 1 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF572 PF04502.13 EPS32123.1 - 0.16 11.6 22.1 0.19 11.3 22.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF2951 PF11166.8 EPS32123.1 - 3 8.1 9.6 0.65 10.3 5.3 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF2951) Aldo_ket_red PF00248.21 EPS32126.1 - 7.1e-37 127.2 0.0 2.4e-35 122.2 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family DNA_meth_N PF18284.1 EPS32127.1 - 7.3 6.6 5.9 2.1 8.3 0.3 2.7 3 0 0 3 3 3 0 DNA methylase N-terminal domain PRCH PF03967.13 EPS32129.1 - 0.14 12.4 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Photosynthetic reaction centre, H-chain N-terminal region Big_1 PF02369.16 EPS32132.1 - 0.078 13.0 0.6 0.66 10.0 0.3 2.4 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 1) MscS_porin PF12795.7 EPS32133.1 - 0.001 18.7 4.3 0.0012 18.5 4.3 1.0 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain DivIC PF04977.15 EPS32133.1 - 0.011 15.5 0.9 0.011 15.5 0.9 1.4 2 0 0 2 2 2 0 Septum formation initiator FlxA PF14282.6 EPS32133.1 - 0.022 14.7 1.6 0.027 14.5 1.6 1.1 1 0 0 1 1 1 0 FlxA-like protein DUF4972 PF16342.5 EPS32133.1 - 0.023 14.4 0.0 0.029 14.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4972) Prefoldin_2 PF01920.20 EPS32133.1 - 0.024 14.6 0.1 0.028 14.4 0.1 1.1 1 0 0 1 1 1 0 Prefoldin subunit Sec2p PF06428.11 EPS32133.1 - 0.067 13.2 2.2 0.082 12.9 2.2 1.1 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Peptidase_S49_N PF08496.10 EPS32133.1 - 0.093 12.8 0.0 0.1 12.6 0.0 1.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF883 PF05957.13 EPS32134.1 - 0.13 12.9 1.4 4.3 8.0 0.4 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) zf-C2H2 PF00096.26 EPS32135.1 - 1.3e-17 63.2 51.4 8.5e-06 26.0 2.0 9.4 9 0 0 9 9 9 5 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EPS32135.1 - 7e-10 38.9 9.2 1.7e-07 31.3 1.6 7.5 8 0 0 8 8 8 4 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EPS32135.1 - 8.1e-10 38.7 16.0 0.00047 20.4 0.3 6.8 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EPS32135.1 - 1e-07 32.1 19.5 0.0036 17.6 0.3 6.3 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EPS32135.1 - 1.4e-07 31.8 17.7 0.00077 20.1 0.6 9.4 10 0 0 10 10 10 4 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EPS32135.1 - 0.00041 20.0 13.3 0.14 12.0 0.1 5.2 5 0 0 5 5 5 2 zinc-finger C2H2-type zf-C2HC_2 PF13913.6 EPS32135.1 - 0.0072 16.2 8.8 5.7 7.0 0.3 4.2 3 0 0 3 3 3 3 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 EPS32135.1 - 0.014 15.3 0.5 0.014 15.3 0.5 5.6 5 0 0 5 5 5 0 C2H2-type zinc finger FOXP-CC PF16159.5 EPS32135.1 - 0.034 14.8 0.4 0.034 14.8 0.4 6.9 6 1 1 7 7 7 0 FOXP coiled-coil domain DEAD PF00270.29 EPS32137.1 - 8.9e-50 168.9 0.0 2.9e-49 167.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPS32137.1 - 5.3e-28 97.6 0.0 3.1e-27 95.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPS32137.1 - 0.024 14.6 0.0 0.069 13.2 0.0 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit HMG_box PF00505.19 EPS32138.1 - 5.5e-11 42.7 1.1 5.5e-11 42.7 1.1 2.9 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EPS32138.1 - 1.2e-07 32.3 0.5 1.2e-07 32.3 0.5 3.1 3 0 0 3 3 3 1 HMG-box domain HMG_box_5 PF14887.6 EPS32138.1 - 0.028 14.4 0.1 0.028 14.4 0.1 2.2 2 0 0 2 2 2 0 HMG (high mobility group) box 5 Antigen_Bd37 PF11641.8 EPS32138.1 - 0.064 12.8 1.7 0.093 12.2 1.7 1.2 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein TrmK PF04816.12 EPS32138.1 - 0.19 11.3 0.1 0.19 11.3 0.1 1.9 3 0 0 3 3 3 0 tRNA (adenine(22)-N(1))-methyltransferase FAM176 PF14851.6 EPS32138.1 - 0.54 9.9 4.1 1.1 8.9 4.1 1.5 1 0 0 1 1 1 0 FAM176 family Astro_capsid_N PF03115.14 EPS32138.1 - 1.7 7.2 5.4 2.6 6.6 5.4 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor FAM183 PF14886.6 EPS32138.1 - 2.8 8.7 10.8 1.7 9.4 8.4 1.8 1 1 1 2 2 2 0 FAM183A and FAM183B related Mito_carr PF00153.27 EPS32140.1 - 8.9e-43 144.1 0.7 9.8e-18 63.9 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein JAB PF01398.21 EPS32141.1 - 1.1e-07 31.9 0.3 2.6e-06 27.4 0.3 2.4 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Pox_L5 PF04872.13 EPS32141.1 - 0.14 12.1 0.1 0.3 11.0 0.1 1.6 1 0 0 1 1 1 0 Poxvirus L5 protein family Abhydrolase_6 PF12697.7 EPS32142.1 - 3.8e-07 30.9 0.3 4.7e-07 30.6 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 EPS32142.1 - 0.00011 22.1 0.1 0.0045 16.9 0.1 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2974 PF11187.8 EPS32142.1 - 0.014 15.0 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.20 EPS32142.1 - 0.014 15.0 0.0 0.036 13.7 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EPS32142.1 - 0.031 13.6 0.0 0.17 11.1 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF3089 PF11288.8 EPS32142.1 - 0.035 13.7 0.1 0.075 12.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Thioesterase PF00975.20 EPS32142.1 - 0.046 13.8 0.0 0.23 11.6 0.0 2.0 2 1 0 2 2 2 0 Thioesterase domain DUF915 PF06028.11 EPS32142.1 - 0.11 11.9 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) CK_II_beta PF01214.18 EPS32143.1 - 1.8e-77 259.3 0.1 2.2e-77 259.0 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit CxC5 PF18718.1 EPS32143.1 - 0.031 14.3 0.5 0.064 13.3 0.0 1.7 2 0 0 2 2 2 0 CxC5 like cysteine cluster associated with KDZ transposases Acetyltransf_3 PF13302.7 EPS32144.1 - 2.9e-18 66.9 0.0 3.5e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPS32144.1 - 3.6e-08 33.7 0.0 4.9e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family US22 PF02393.16 EPS32144.1 - 0.075 13.3 0.1 0.13 12.5 0.1 1.5 1 1 0 1 1 1 0 US22 like Acetyltransf_8 PF13523.6 EPS32144.1 - 0.095 12.4 0.0 0.12 12.1 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Transp_cyt_pur PF02133.15 EPS32145.1 - 3.1e-27 95.5 31.2 5.2e-27 94.7 31.2 1.4 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin UPF0139 PF03669.13 EPS32145.1 - 0.019 14.8 1.5 0.061 13.2 0.2 2.5 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0139) LptF_LptG PF03739.14 EPS32145.1 - 7.1 5.4 21.1 4.1 6.2 0.1 3.2 3 0 0 3 3 3 0 Lipopolysaccharide export system permease LptF/LptG Hemerythrin PF01814.23 EPS32149.1 - 4e-13 50.1 0.3 5.3e-13 49.7 0.3 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DDE_3 PF13358.6 EPS32150.1 - 2.7e-31 108.3 0.0 9.4e-31 106.5 0.0 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease rve PF00665.26 EPS32150.1 - 1.9e-05 24.8 0.0 6.3e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain DDE_1 PF03184.19 EPS32150.1 - 2.8e-05 23.9 0.0 4.1e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_33 PF13592.6 EPS32150.1 - 4.1e-05 23.1 0.1 0.0001 21.9 0.1 1.7 1 0 0 1 1 1 1 Winged helix-turn helix DDE_Tnp_ISAZ013 PF07592.11 EPS32150.1 - 0.0055 15.7 0.0 2 7.3 0.0 2.1 2 0 0 2 2 2 2 Rhodopirellula transposase DDE domain GCP_C_terminal PF04130.13 EPS32150.1 - 0.053 13.0 0.1 0.089 12.2 0.1 1.3 1 0 0 1 1 1 0 Gamma tubulin complex component C-terminal NB-ARC PF00931.22 EPS32151.1 - 6.1e-07 28.9 0.0 0.017 14.3 0.0 2.2 2 0 0 2 2 2 2 NB-ARC domain TPR_10 PF13374.6 EPS32151.1 - 1.7e-06 27.7 0.2 8e-06 25.6 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat Ses_B PF17046.5 EPS32151.1 - 0.00017 21.5 1.4 0.00034 20.5 1.4 1.5 1 0 0 1 1 1 1 SesB domain on fungal death-pathway protein TPR_12 PF13424.6 EPS32151.1 - 0.00069 19.9 0.1 0.0031 17.8 0.1 2.2 1 1 0 1 1 1 1 Tetratricopeptide repeat NACHT PF05729.12 EPS32151.1 - 0.0008 19.4 0.0 0.0017 18.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.6 EPS32151.1 - 0.0024 18.1 0.0 0.014 15.6 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 EPS32151.1 - 0.012 15.2 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EPS32151.1 - 0.066 13.6 0.6 0.57 10.5 0.6 2.3 1 1 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.17 EPS32151.1 - 0.14 11.9 0.0 0.39 10.4 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein CxC7 PF18866.1 EPS32152.1 - 0.029 14.5 0.0 0.036 14.2 0.0 1.2 1 0 0 1 1 1 0 CxC7 like cysteine cluster associated with KDZ transposases CENP-T_C PF15511.6 EPS32153.1 - 0.028 14.5 0.1 0.058 13.5 0.0 1.5 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T histone fold AAA_assoc PF14363.6 EPS32153.1 - 0.15 12.4 0.1 0.26 11.6 0.1 1.4 1 0 0 1 1 1 0 Domain associated at C-terminal with AAA DUF2752 PF10825.8 EPS32155.1 - 0.21 11.7 8.9 58 3.9 0.1 4.7 3 2 2 5 5 5 0 Protein of unknown function (DUF2752) DUF2457 PF10446.9 EPS32155.1 - 7.4 5.6 6.0 8.4 5.4 6.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RRP14 PF15459.6 EPS32155.1 - 8.8 7.0 8.3 4.8 7.9 0.5 3.2 1 1 4 5 5 5 0 60S ribosome biogenesis protein Rrp14 DUF3754 PF12576.8 EPS32156.1 - 0.095 12.6 0.1 0.45 10.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) NACHT PF05729.12 EPS32158.1 - 0.0002 21.3 0.2 0.00077 19.4 0.0 2.2 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 EPS32158.1 - 0.0012 19.2 5.3 0.0016 18.8 0.2 3.3 3 2 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EPS32158.1 - 0.045 14.0 0.4 0.35 11.1 0.0 2.7 2 1 1 3 3 3 0 AAA domain p450 PF00067.22 EPS32160.1 - 1.6e-38 132.7 0.0 2.7e-38 131.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.16 EPS32161.1 - 6e-36 124.1 33.7 6e-36 124.1 33.7 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 EPS32161.1 - 1.7e-06 27.6 3.3 1.7e-06 27.6 3.3 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Peptidase_M20 PF01546.28 EPS32162.1 - 1.6e-10 41.0 1.4 3.1e-10 40.1 1.4 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EPS32162.1 - 8.1e-10 38.6 0.0 2.1e-09 37.2 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Fungal_trans_2 PF11951.8 EPS32163.1 - 4.2e-11 42.3 0.5 4.1e-07 29.2 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Glyco_hydro_6 PF01341.17 EPS32164.1 - 4.2e-107 358.4 0.3 5.5e-107 358.0 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.18 EPS32164.1 - 1.5e-12 47.2 10.5 1.5e-12 47.2 10.5 2.6 2 0 0 2 2 2 1 Fungal cellulose binding domain MGC-24 PF05283.11 EPS32164.1 - 0.69 10.4 9.1 1.8 9.0 9.1 1.7 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Fungal_lectin PF07938.12 EPS32165.1 - 0.061 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Fungal fucose-specific lectin VCBS PF13517.6 EPS32165.1 - 0.34 11.5 2.3 7.6 7.2 0.1 3.7 5 0 0 5 5 5 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcA_TcB_BD PF18276.1 EPS32167.1 - 2.7e-116 387.7 0.1 4.7e-116 386.9 0.1 1.4 1 0 0 1 1 1 1 Tc toxin complex TcA C-terminal TcB-binding domain Neuraminidase PF18413.1 EPS32167.1 - 3.9e-26 91.7 0.2 3.9e-26 91.7 0.2 2.5 3 0 0 3 3 3 1 Neuraminidase-like domain DUF16 PF01519.16 EPS32167.1 - 0.37 11.3 1.5 1.2 9.7 1.5 1.8 1 0 0 1 1 1 0 Protein of unknown function DUF16 ADIP PF11559.8 EPS32167.1 - 3.6 7.7 11.6 11 6.1 11.6 1.8 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding SpvB PF03534.13 EPS32168.1 - 3e-108 361.4 0.1 4.8e-108 360.7 0.1 1.3 1 0 0 1 1 1 1 Salmonella virulence plasmid 65kDa B protein TcdB_toxin_midN PF12256.8 EPS32168.1 - 4.5e-30 104.3 0.0 5.6e-25 87.7 0.0 5.2 5 1 1 6 6 6 2 Insecticide toxin TcdB middle/N-terminal region TcdB_toxin_midC PF12255.8 EPS32168.1 - 3e-29 102.0 0.9 1.2e-28 100.0 0.9 2.1 1 0 0 1 1 1 1 Insecticide toxin TcdB middle/C-terminal region VCBS PF13517.6 EPS32168.1 - 2.1e-05 25.0 0.2 0.092 13.3 0.1 3.9 2 1 2 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella RHS_repeat PF05593.14 EPS32168.1 - 0.00041 20.8 25.0 0.043 14.3 1.1 7.9 8 1 1 9 9 9 2 RHS Repeat Na_Ca_ex PF01699.24 EPS32169.1 - 1.9e-31 109.1 38.2 6.1e-18 65.2 16.8 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein UPF0261 PF06792.11 EPS32170.1 - 1e-146 489.1 0.0 2e-146 488.1 0.0 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0261) AdoHcyase PF05221.17 EPS32171.1 - 1e-129 431.9 0.0 7.8e-74 248.5 0.1 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 EPS32171.1 - 1.2e-81 272.6 2.5 1.9e-81 271.9 2.5 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 EPS32171.1 - 1.7e-06 27.5 0.1 4.5e-06 26.1 0.1 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 EPS32171.1 - 0.0011 18.5 0.2 0.0021 17.7 0.2 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 EPS32171.1 - 0.011 16.0 0.1 0.023 14.9 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain ELFV_dehydrog PF00208.21 EPS32171.1 - 0.037 13.8 0.1 0.06 13.1 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Oxidored_nitro PF00148.19 EPS32171.1 - 0.042 12.6 0.1 0.34 9.6 0.0 2.3 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase Urocanase PF01175.18 EPS32171.1 - 0.11 12.2 0.4 0.19 11.3 0.4 1.4 1 0 0 1 1 1 0 Urocanase Rossmann-like domain zf-C2H2 PF00096.26 EPS32174.1 - 3.5e-07 30.3 12.2 8.1e-06 26.0 2.8 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EPS32174.1 - 2.2e-05 24.6 2.5 2.2e-05 24.6 2.5 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EPS32174.1 - 0.00024 21.7 1.2 0.00024 21.7 1.2 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.12 EPS32174.1 - 0.00036 20.8 3.8 0.00063 20.0 3.8 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 EPS32174.1 - 0.00075 19.8 0.5 0.00075 19.8 0.5 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EPS32174.1 - 0.0034 17.6 0.5 0.0095 16.2 0.5 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding DUF1178 PF06676.11 EPS32174.1 - 0.0053 17.1 1.1 0.01 16.2 1.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1178) DUF2225 PF09986.9 EPS32174.1 - 0.007 16.1 0.2 0.011 15.4 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_6 PF13912.6 EPS32174.1 - 0.013 15.5 0.4 0.03 14.3 0.4 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_5 PF13909.6 EPS32174.1 - 0.067 13.0 0.2 0.067 13.0 0.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-BED PF02892.15 EPS32174.1 - 0.12 12.4 4.6 0.25 11.4 4.6 1.6 1 0 0 1 1 1 0 BED zinc finger PEP_hydrolase PF09370.10 EPS32175.1 - 8.3e-134 444.9 0.3 9.4e-134 444.7 0.3 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate hydrolase-like NMO PF03060.15 EPS32175.1 - 0.00016 21.1 0.1 0.00026 20.5 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase adh_short PF00106.25 EPS32176.1 - 1e-40 139.3 0.0 1.3e-40 139.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS32176.1 - 5e-38 131.0 0.1 4.1e-35 121.4 0.0 2.0 1 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPS32176.1 - 2.2e-12 47.3 0.0 3.4e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPS32176.1 - 0.00045 19.8 0.0 0.0024 17.3 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_hydro_79C PF16862.5 EPS32177.1 - 8.1e-23 81.3 0.0 2e-22 80.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 79 C-terminal beta domain Ring_hydroxyl_A PF00848.19 EPS32179.1 - 1.3e-25 90.7 7.5 1e-22 81.2 7.5 2.2 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) CorC_HlyC PF03471.17 EPS32179.1 - 0.17 11.9 0.0 2 8.5 0.0 2.4 3 0 0 3 3 3 0 Transporter associated domain HATPase_c PF02518.26 EPS32180.1 - 2.4e-15 57.0 0.0 4.5e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EPS32180.1 - 3.7e-14 52.8 0.0 7.7e-14 51.8 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EPS32180.1 - 7.4e-10 38.7 0.0 2.2e-09 37.2 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 EPS32180.1 - 0.014 15.2 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Kelch_6 PF13964.6 EPS32181.1 - 0.00012 22.2 7.8 0.1 12.9 0.1 5.5 4 1 1 5 5 5 2 Kelch motif Rax2 PF12768.7 EPS32181.1 - 0.0016 18.0 0.7 0.009 15.5 0.3 2.3 2 1 0 2 2 2 1 Cortical protein marker for cell polarity TMEM154 PF15102.6 EPS32181.1 - 0.0077 16.1 0.0 0.025 14.5 0.0 1.8 1 0 0 1 1 1 1 TMEM154 protein family Glycophorin_A PF01102.18 EPS32181.1 - 0.01 16.0 0.0 0.028 14.7 0.0 1.7 1 0 0 1 1 1 0 Glycophorin A Phage_holin_2_4 PF16082.5 EPS32181.1 - 0.012 15.3 0.2 0.029 14.1 0.2 1.6 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Mid2 PF04478.12 EPS32181.1 - 0.015 15.2 0.3 0.034 14.0 0.3 1.6 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Coiled PF05710.12 EPS32181.1 - 0.085 13.7 3.3 0.38 11.6 3.3 2.1 1 0 0 1 1 1 0 Coiled coil Kelch_5 PF13854.6 EPS32181.1 - 0.099 12.7 1.2 23 5.1 0.0 3.3 3 0 0 3 3 3 0 Kelch motif EphA2_TM PF14575.6 EPS32181.1 - 0.1 13.5 0.0 0.21 12.5 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain HAT PF02184.16 EPS32183.1 - 1.8e-21 75.8 81.6 1.7e-13 50.3 6.0 14.1 15 0 0 15 15 15 5 HAT (Half-A-TPR) repeat TPR_19 PF14559.6 EPS32183.1 - 1.9e-20 73.1 1.3 1.3e-05 25.6 0.0 7.7 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 EPS32183.1 - 3.9e-20 70.8 31.4 0.0072 17.1 0.2 11.7 8 3 5 13 13 13 8 Tetratricopeptide repeat Suf PF05843.14 EPS32183.1 - 3.5e-18 66.6 26.6 1.8e-05 24.9 1.3 6.6 3 1 3 6 6 6 4 Suppressor of forked protein (Suf) TPR_17 PF13431.6 EPS32183.1 - 2e-10 40.3 6.8 0.047 14.1 0.1 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 EPS32183.1 - 2.1e-07 30.6 9.3 2 8.8 0.1 7.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 EPS32183.1 - 7.5e-06 25.7 22.4 2.9 8.2 0.0 9.2 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_15 PF13429.6 EPS32183.1 - 1.7e-05 24.2 15.7 0.031 13.5 0.8 5.8 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 EPS32183.1 - 0.0019 18.8 13.9 16 6.2 0.1 8.1 8 2 2 10 10 10 0 Tetratricopeptide repeat TPR_1 PF00515.28 EPS32183.1 - 0.0085 15.9 4.7 24 4.9 0.1 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 EPS32183.1 - 0.013 16.0 22.6 6.9 7.5 0.0 8.4 9 0 0 9 9 9 0 Tetratricopeptide repeat ER PF01133.17 EPS32183.1 - 0.099 12.7 0.9 2.5 8.2 0.2 3.5 2 2 2 4 4 4 0 Enhancer of rudimentary U3_assoc_6 PF08640.11 EPS32183.1 - 0.61 10.2 31.8 0.091 12.8 1.8 7.1 7 2 2 9 9 9 0 U3 small nucleolar RNA-associated protein 6 TPR_12 PF13424.6 EPS32183.1 - 2.5 8.5 23.6 7.3 7.0 0.0 7.7 10 0 0 10 10 9 0 Tetratricopeptide repeat NifW PF03206.14 EPS32183.1 - 3.3 8.3 6.1 2.4 8.7 0.2 3.7 4 0 0 4 4 4 0 Nitrogen fixation protein NifW Nop PF01798.18 EPS32184.1 - 3.8e-63 213.0 0.1 4.9e-63 212.7 0.1 1.1 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 EPS32184.1 - 5.4e-48 162.9 0.3 1.5e-47 161.4 0.3 1.8 1 1 0 1 1 1 1 Prp31 C terminal domain PhyH PF05721.13 EPS32186.1 - 2.6e-08 34.4 0.0 5.1e-08 33.4 0.0 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF2379 PF09543.10 EPS32186.1 - 0.19 11.9 0.0 0.39 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) DEC-1_N PF04625.13 EPS32187.1 - 0.44 9.5 5.0 0.66 8.9 5.0 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Aldo_ket_red PF00248.21 EPS32188.1 - 2.2e-64 217.5 0.0 2.5e-64 217.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-H2C2_2 PF13465.6 EPS32189.1 - 3.9e-07 30.2 9.5 2.7e-06 27.6 0.9 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.6 EPS32189.1 - 1.4e-05 24.9 1.3 0.029 14.4 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EPS32189.1 - 2.2e-05 24.6 0.8 2.2e-05 24.6 0.8 3.6 4 1 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPS32189.1 - 0.0011 19.6 10.5 0.0035 18.0 0.5 3.3 4 0 0 4 4 3 2 C2H2-type zinc finger FOXP-CC PF16159.5 EPS32189.1 - 0.017 15.7 19.5 0.021 15.4 0.0 4.6 4 1 1 5 5 5 0 FOXP coiled-coil domain SUIM_assoc PF16619.5 EPS32189.1 - 0.018 15.1 0.7 0.063 13.3 0.7 1.9 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 zf-C2H2_jaz PF12171.8 EPS32189.1 - 0.024 14.9 3.7 0.29 11.5 0.3 3.2 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 EPS32189.1 - 0.072 12.9 1.4 0.29 10.9 0.0 2.2 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-C2H2_2 PF12756.7 EPS32189.1 - 0.58 10.5 3.6 6.4 7.2 0.1 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 EPS32189.1 - 2 8.9 3.6 40 4.8 0.0 3.0 3 0 0 3 3 3 0 Zinc-finger of C2H2 type MGC-24 PF05283.11 EPS32189.1 - 2.4 8.6 4.4 1.1 9.8 0.2 2.5 3 0 0 3 3 3 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin SNF2_N PF00176.23 EPS32190.1 - 6.4e-56 189.6 0.1 1e-55 188.9 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.24 EPS32190.1 - 5.6e-24 83.8 3.5 4.6e-16 58.5 0.4 3.2 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.6 EPS32190.1 - 2.1e-20 73.0 0.7 6.4e-20 71.4 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Helicase_C PF00271.31 EPS32190.1 - 6.4e-19 68.3 0.1 2e-18 66.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPS32190.1 - 9.6e-08 32.2 1.2 2.3e-05 24.5 0.0 3.5 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit Cdh1_DBD_1 PF18196.1 EPS32190.1 - 3.3e-06 27.4 1.7 3.2e-05 24.2 0.2 4.5 3 1 1 4 4 4 2 Chromodomain helicase DNA-binding domain 1 SLIDE PF09111.10 EPS32190.1 - 0.068 13.2 0.3 1.1 9.3 0.0 3.2 3 0 0 3 3 3 0 SLIDE CHDCT2 PF08074.11 EPS32190.1 - 0.083 13.1 2.6 0.12 12.6 0.0 2.7 3 0 0 3 3 3 0 CHDCT2 (NUC038) domain ABC_tran PF00005.27 EPS32191.1 - 2.7e-34 118.6 0.0 6.2e-16 59.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 EPS32191.1 - 3e-14 52.6 5.5 3e-14 52.6 5.5 1.9 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 EPS32191.1 - 1.1e-10 41.4 1.7 0.0029 17.1 0.0 4.0 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EPS32191.1 - 2.9e-10 40.4 3.9 0.21 11.4 1.6 4.2 2 2 2 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system Fer4 PF00037.27 EPS32191.1 - 2.1e-05 24.1 2.9 2.1e-05 24.1 2.9 2.7 3 0 0 3 3 3 1 4Fe-4S binding domain Rad17 PF03215.15 EPS32191.1 - 2.6e-05 24.2 0.2 0.02 14.8 0.0 2.8 2 1 1 3 3 3 1 Rad17 P-loop domain AAA_22 PF13401.6 EPS32191.1 - 2.8e-05 24.4 0.2 0.0089 16.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 EPS32191.1 - 3.4e-05 24.3 0.0 0.05 14.0 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.6 EPS32191.1 - 4.1e-05 23.5 0.9 0.23 11.1 0.0 3.2 2 1 0 3 3 3 2 AAA ATPase domain AAA_16 PF13191.6 EPS32191.1 - 6.8e-05 23.3 0.0 0.1 13.0 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EPS32191.1 - 0.00014 21.8 0.1 0.44 10.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Fer4_6 PF12837.7 EPS32191.1 - 0.00039 20.4 12.0 0.00095 19.1 2.0 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_29 PF13555.6 EPS32191.1 - 0.00044 19.9 0.3 0.59 9.9 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_13 PF13166.6 EPS32191.1 - 0.00086 18.1 0.0 0.0018 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EPS32191.1 - 0.00098 19.7 0.0 2.7 8.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 EPS32191.1 - 0.0012 18.6 1.9 0.087 12.5 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EPS32191.1 - 0.0015 18.0 0.1 0.034 13.6 0.1 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 EPS32191.1 - 0.0022 18.3 0.7 0.93 9.9 0.0 3.0 3 0 0 3 3 2 1 RNA helicase Fer4_21 PF14697.6 EPS32191.1 - 0.0022 18.1 11.7 0.0053 16.9 11.7 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain SRP54 PF00448.22 EPS32191.1 - 0.0034 17.0 2.3 0.12 11.9 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_33 PF13671.6 EPS32191.1 - 0.0066 16.6 0.0 1.1 9.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 EPS32191.1 - 0.01 15.9 0.1 0.13 12.3 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EPS32191.1 - 0.012 15.8 0.0 1.9 8.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fer4_10 PF13237.6 EPS32191.1 - 0.013 15.6 15.4 0.016 15.3 1.5 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain NB-ARC PF00931.22 EPS32191.1 - 0.014 14.6 0.0 1.1 8.4 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_23 PF13476.6 EPS32191.1 - 0.015 15.8 1.6 0.7 10.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EPS32191.1 - 0.016 15.1 1.6 1.3 8.9 0.0 2.5 2 0 0 2 2 2 0 NACHT domain Thymidylate_kin PF02223.17 EPS32191.1 - 0.035 13.8 0.1 10 5.7 0.0 2.7 2 0 0 2 2 2 0 Thymidylate kinase Fer4_9 PF13187.6 EPS32191.1 - 0.045 13.9 11.4 0.098 12.8 11.4 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 EPS32191.1 - 0.045 14.3 1.4 0.045 14.3 1.4 2.4 1 1 2 3 3 3 0 4Fe-4S dicluster domain AAA_30 PF13604.6 EPS32191.1 - 0.048 13.4 0.5 3 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain VirE PF05272.11 EPS32191.1 - 0.06 13.1 0.0 6.2 6.5 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E DnaB_C PF03796.15 EPS32191.1 - 0.062 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Fer4_16 PF13484.6 EPS32191.1 - 0.065 14.2 0.2 0.065 14.2 0.2 2.6 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain DLIC PF05783.11 EPS32191.1 - 0.093 11.5 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) AAA_14 PF13173.6 EPS32191.1 - 0.12 12.4 1.0 5.1 7.1 0.0 2.9 2 2 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EPS32191.1 - 0.13 12.0 2.1 0.17 11.6 0.1 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 EPS32191.1 - 0.13 12.3 0.1 7.9 6.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 EPS32191.1 - 0.14 12.4 0.0 16 5.8 0.0 2.8 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ATPase PF06745.13 EPS32191.1 - 0.15 11.4 0.1 0.32 10.3 0.1 1.5 1 0 0 1 1 1 0 KaiC MMR_HSR1 PF01926.23 EPS32191.1 - 0.18 11.9 0.3 29 4.8 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Fer4_8 PF13183.6 EPS32191.1 - 0.31 11.5 6.7 0.32 11.5 0.2 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.7 EPS32191.1 - 2 8.7 9.7 0.29 11.3 1.1 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.6 EPS32191.1 - 9.3 6.9 11.2 0.27 11.8 1.2 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Glyco_hydro_28 PF00295.17 EPS32193.1 - 4.7e-104 348.0 20.3 5.7e-104 347.7 20.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 CytB6-F_Fe-S PF08802.10 EPS32193.1 - 0.24 11.5 0.8 0.68 10.0 0.8 1.8 1 0 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit FF PF01846.19 EPS32195.1 - 7.7e-57 189.3 23.2 4.4e-15 55.6 0.5 7.3 6 1 0 6 6 6 6 FF domain WW PF00397.26 EPS32195.1 - 3e-17 62.4 13.2 1.2e-08 34.9 0.2 2.6 2 0 0 2 2 2 2 WW domain RhoGAP-FF1 PF16512.5 EPS32195.1 - 0.0045 17.6 11.6 2.4 8.9 0.1 4.7 3 1 1 4 4 4 2 p190-A and -B Rho GAPs FF domain DUF4241 PF14025.6 EPS32195.1 - 0.069 13.4 0.1 0.25 11.6 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4241) Glyco_hyd_101C PF17451.2 EPS32195.1 - 0.31 11.3 6.9 5.7 7.3 2.2 2.8 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain EMP24_GP25L PF01105.24 EPS32195.1 - 2.8 7.9 7.2 0.11 12.4 0.7 2.0 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD HycH PF07450.11 EPS32195.1 - 3.9 7.9 7.5 0.82 10.0 0.7 3.0 3 1 1 4 4 4 0 Formate hydrogenlyase maturation protein HycH Trs65 PF12735.7 EPS32196.1 - 1.7e-102 343.1 0.0 2.1e-102 342.8 0.0 1.1 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 Mpv17_PMP22 PF04117.12 EPS32197.1 - 1.3e-18 66.9 0.1 1.3e-18 66.9 0.1 2.2 2 0 0 2 2 2 1 Mpv17 / PMP22 family PGK PF00162.19 EPS32198.1 - 4.5e-150 499.8 3.3 5.1e-150 499.6 3.3 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DUF3530 PF12048.8 EPS32198.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DSS1_SEM1 PF05160.13 EPS32200.1 - 2.2e-24 85.3 16.2 3e-24 84.9 16.2 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family DNA_pol_phi PF04931.13 EPS32200.1 - 5.5 5.0 11.0 5.9 4.9 11.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi DUF3808 PF10300.9 EPS32201.1 - 3e-161 537.4 0.0 3.5e-161 537.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) MFS_1 PF07690.16 EPS32202.1 - 9e-39 133.4 64.6 9.6e-37 126.7 37.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3522 PF12036.8 EPS32202.1 - 0.031 14.6 0.6 0.031 14.6 0.6 2.9 2 1 0 3 3 3 0 Protein of unknown function (DUF3522) DUF5455 PF17537.2 EPS32202.1 - 0.19 12.1 2.8 0.5 10.8 1.4 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5455) AMP-binding PF00501.28 EPS32203.1 - 3.8e-283 938.3 0.0 3.9e-80 269.5 0.0 4.2 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.20 EPS32203.1 - 5.7e-241 800.0 0.0 1.7e-53 181.9 0.0 9.2 9 1 0 9 9 9 7 Condensation domain PP-binding PF00550.25 EPS32203.1 - 1.3e-48 163.2 4.3 3.6e-11 43.3 0.0 5.9 5 0 0 5 5 5 5 Phosphopantetheine attachment site AMP-binding_C PF13193.6 EPS32203.1 - 4.5e-06 27.6 0.2 0.28 12.2 0.1 4.1 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain Cyclophil_like2 PF18050.1 EPS32203.1 - 0.011 15.7 0.0 0.26 11.2 0.0 3.1 4 0 0 4 4 4 0 Cyclophilin-like family Transferase PF02458.15 EPS32203.1 - 0.022 13.4 0.1 4.3 5.9 0.0 3.1 4 0 0 4 4 4 0 Transferase family DUF5122 PF17164.4 EPS32203.1 - 2 8.8 5.6 21 5.5 0.1 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF5122) beta-propeller ABC_tran PF00005.27 EPS32205.1 - 2.8e-47 160.7 0.0 6e-25 88.4 0.2 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EPS32205.1 - 7.5e-29 101.2 28.1 4.3e-19 69.2 15.1 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EPS32205.1 - 1.4e-07 31.2 5.2 0.0083 15.6 2.4 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EPS32205.1 - 1.6e-07 32.0 1.1 0.0024 18.4 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EPS32205.1 - 1.2e-06 28.1 0.9 0.0004 20.1 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EPS32205.1 - 3.5e-06 27.0 0.2 0.0065 16.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA PF00004.29 EPS32205.1 - 3.2e-05 24.3 0.4 0.084 13.3 0.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EPS32205.1 - 6.7e-05 23.2 1.5 0.024 14.9 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EPS32205.1 - 8.3e-05 22.3 0.1 0.0038 16.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EPS32205.1 - 8.5e-05 23.0 0.0 0.013 15.9 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 EPS32205.1 - 0.00018 21.3 0.1 0.22 11.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EPS32205.1 - 0.0002 21.7 0.3 0.033 14.6 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_21 PF13304.6 EPS32205.1 - 0.00048 20.0 3.7 0.02 14.7 0.0 3.2 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EPS32205.1 - 0.00058 19.9 0.3 0.4 10.8 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 EPS32205.1 - 0.00067 19.8 0.2 0.083 13.1 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.6 EPS32205.1 - 0.00097 18.9 0.3 0.1 12.3 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.22 EPS32205.1 - 0.0011 18.3 0.0 1.3 8.1 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain AAA_7 PF12775.7 EPS32205.1 - 0.0017 17.9 1.1 0.67 9.4 0.1 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region T2SSE PF00437.20 EPS32205.1 - 0.0082 15.2 0.3 2 7.4 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein IstB_IS21 PF01695.17 EPS32205.1 - 0.011 15.5 1.9 9.2 6.0 0.1 3.5 3 0 0 3 3 3 0 IstB-like ATP binding protein SbcCD_C PF13558.6 EPS32205.1 - 0.014 15.6 0.1 11 6.4 0.0 3.3 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 EPS32205.1 - 0.015 15.3 1.8 1.3 9.1 0.1 3.0 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.25 EPS32205.1 - 0.024 14.3 0.7 2.8 7.5 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Roc PF08477.13 EPS32205.1 - 0.032 14.5 0.6 15 5.8 0.0 2.8 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 EPS32205.1 - 0.036 13.8 0.5 7.2 6.3 0.0 2.9 2 1 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 EPS32205.1 - 0.042 13.6 0.1 3.7 7.2 0.0 2.7 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase FtsK_SpoIIIE PF01580.18 EPS32205.1 - 0.06 12.7 0.1 4.3 6.6 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family NACHT PF05729.12 EPS32205.1 - 0.097 12.6 0.8 3 7.7 0.0 2.5 2 0 0 2 2 2 0 NACHT domain TsaE PF02367.17 EPS32205.1 - 0.098 12.7 0.1 5.8 6.9 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 EPS32205.1 - 0.11 12.4 0.4 0.3 11.0 0.4 1.7 1 0 0 1 1 1 0 Rad17 P-loop domain PRK PF00485.18 EPS32205.1 - 0.11 12.2 1.2 4 7.1 0.5 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Septin PF00735.18 EPS32205.1 - 0.13 11.6 0.2 4.9 6.3 0.0 2.2 2 0 0 2 2 2 0 Septin DUF815 PF05673.13 EPS32205.1 - 0.23 10.6 0.7 1 8.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PduV-EutP PF10662.9 EPS32205.1 - 0.26 11.0 2.6 1.2 8.9 0.2 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 EPS32205.1 - 0.42 11.2 1.4 14 6.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EPS32205.1 - 1 8.9 2.9 17 4.9 0.3 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Nup160 PF11715.8 EPS32207.1 - 4.8e-156 520.6 3.4 6.6e-156 520.1 3.4 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Rad51 PF08423.11 EPS32208.1 - 9.7e-129 428.1 0.0 1.2e-128 427.8 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 EPS32208.1 - 1.5e-09 37.7 0.0 2.2e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 EPS32208.1 - 1.9e-09 37.4 0.0 2.7e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 EPS32208.1 - 2.7e-05 24.7 0.3 8.6e-05 23.1 0.1 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain ATPase PF06745.13 EPS32208.1 - 0.00011 21.7 1.2 0.0004 19.8 1.2 1.9 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 EPS32208.1 - 0.022 14.1 0.1 0.13 11.5 0.0 1.9 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain PAXNEB PF05625.11 EPS32208.1 - 0.095 11.8 2.5 0.42 9.7 1.3 2.0 1 1 1 2 2 2 0 PAXNEB protein AAA_22 PF13401.6 EPS32208.1 - 0.15 12.3 0.1 0.54 10.5 0.1 1.8 1 1 0 1 1 1 0 AAA domain Fungal_trans PF04082.18 EPS32212.1 - 4.8e-14 52.0 0.0 1.5e-13 50.4 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS32212.1 - 3.1e-06 27.2 14.9 4.8e-06 26.6 14.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.21 EPS32213.1 - 1e-55 189.0 0.0 1.3e-55 188.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Zn_clus PF00172.18 EPS32214.1 - 0.00018 21.6 8.8 0.00035 20.6 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 3HCDH_N PF02737.18 EPS32215.1 - 4.4e-23 82.1 0.0 9.4e-23 81.0 0.0 1.6 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EPS32215.1 - 7.8e-20 71.3 0.0 1.4e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.23 EPS32215.1 - 0.016 15.2 0.1 0.027 14.5 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sacchrp_dh_NADP PF03435.18 EPS32215.1 - 0.021 15.1 0.0 0.034 14.4 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ApbA PF02558.16 EPS32215.1 - 0.06 13.0 0.0 0.13 11.9 0.0 1.6 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.14 EPS32215.1 - 0.094 11.9 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EPS32215.1 - 0.1 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Aa_trans PF01490.18 EPS32216.1 - 4.8e-20 71.7 27.2 3.8e-13 48.9 10.1 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein DUF5373 PF17343.2 EPS32216.1 - 8.9 6.1 7.7 0.53 10.1 2.4 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5373) ECH_1 PF00378.20 EPS32217.1 - 1.8e-33 115.9 0.0 4e-33 114.8 0.0 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EPS32217.1 - 6.9e-18 65.2 0.0 8e-18 65.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DUF5408 PF17402.2 EPS32218.1 - 0.21 11.5 0.6 0.38 10.7 0.6 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5408) CPL PF08144.11 EPS32220.1 - 1.1e-27 97.2 1.3 1.3e-25 90.5 0.0 3.8 3 1 0 3 3 3 1 CPL (NUC119) domain SCHIP-1 PF10148.9 EPS32220.1 - 0.00035 20.3 5.4 0.00035 20.3 5.4 2.0 2 0 0 2 2 2 1 Schwannomin-interacting protein 1 PUF PF00806.19 EPS32220.1 - 0.057 13.1 0.0 35 4.3 0.0 3.7 3 0 0 3 3 3 0 Pumilio-family RNA binding repeat Hid1 PF12722.7 EPS32220.1 - 2.5 6.1 16.5 3.8 5.5 16.5 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nop14 PF04147.12 EPS32220.1 - 3.3 5.8 35.0 5.3 5.1 35.0 1.3 1 0 0 1 1 1 0 Nop14-like family Macoilin PF09726.9 EPS32220.1 - 6.6 5.2 21.2 12 4.3 21.2 1.3 1 0 0 1 1 1 0 Macoilin family zf-BED PF02892.15 EPS32224.1 - 0.037 14.0 0.3 0.09 12.8 0.3 1.6 1 0 0 1 1 1 0 BED zinc finger Zn_clus PF00172.18 EPS32224.1 - 0.073 13.2 8.3 0.18 11.9 8.3 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_pol_B_palm PF14792.6 EPS32226.1 - 7.6e-32 109.9 0.0 2.2e-31 108.4 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 EPS32226.1 - 8.9e-24 83.5 0.1 2.5e-22 78.8 0.1 2.6 2 0 0 2 2 2 1 DNA polymerase beta thumb HHH_8 PF14716.6 EPS32226.1 - 1.9e-18 66.6 0.2 5.9e-18 65.0 0.2 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 EPS32226.1 - 7.2e-17 60.9 0.0 2.7e-16 59.1 0.0 2.1 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda BRCT PF00533.26 EPS32226.1 - 0.013 15.9 0.0 0.028 14.8 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain NTP_transf_2 PF01909.23 EPS32226.1 - 0.054 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 Nucleotidyltransferase domain ATP-synt_10 PF05176.14 EPS32227.1 - 6.4e-87 291.0 0.1 1.1e-86 290.2 0.0 1.4 2 0 0 2 2 2 1 ATP10 protein V-SNARE_C PF12352.8 EPS32228.1 - 9.7e-14 51.4 0.0 9.7e-14 51.4 0.0 2.8 4 0 0 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus GOLGA2L5 PF15070.6 EPS32228.1 - 0.0011 17.8 5.8 0.0015 17.3 5.8 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 STAT_alpha PF01017.20 EPS32228.1 - 0.026 14.4 3.4 0.069 13.0 3.2 1.8 1 1 0 1 1 1 0 STAT protein, all-alpha domain Not3 PF04065.15 EPS32228.1 - 0.17 11.3 2.2 1.9 7.9 0.6 2.0 1 1 1 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component TPR_MLP1_2 PF07926.12 EPS32228.1 - 0.18 11.9 9.6 0.15 12.1 3.3 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Sec34 PF04136.15 EPS32228.1 - 0.2 11.5 5.3 4 7.3 1.6 2.6 2 1 1 3 3 3 0 Sec34-like family Syntaxin-6_N PF09177.11 EPS32228.1 - 0.28 11.8 6.5 0.15 12.7 3.7 2.0 3 0 0 3 3 3 0 Syntaxin 6, N-terminal FUSC PF04632.12 EPS32228.1 - 3.6 6.0 10.3 4.5 5.7 10.3 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF349 PF03993.12 EPS32228.1 - 4.1 7.8 6.6 1.8 8.9 2.9 2.3 2 1 0 2 2 2 0 Domain of Unknown Function (DUF349) Ribosomal_L29 PF00831.23 EPS32229.1 - 2.3e-18 65.9 3.3 2.3e-18 65.9 3.3 1.9 2 0 0 2 2 2 1 Ribosomal L29 protein DUF3573 PF12097.8 EPS32229.1 - 0.01 14.7 0.6 0.012 14.5 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Herpes_UL49_2 PF04823.12 EPS32229.1 - 0.023 14.8 0.3 0.042 14.0 0.3 1.4 1 0 0 1 1 1 0 Herpesvirus UL49 tegument protein Cortex-I_coil PF09304.10 EPS32229.1 - 0.032 14.4 1.5 0.032 14.4 1.5 1.6 2 0 0 2 2 2 0 Cortexillin I, coiled coil CorA PF01544.18 EPS32229.1 - 0.079 12.3 2.0 0.085 12.2 2.0 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Prefoldin PF02996.17 EPS32229.1 - 0.19 11.6 3.6 2.3 8.1 1.5 2.3 1 1 1 2 2 2 0 Prefoldin subunit Med16 PF11635.8 EPS32230.1 - 6.1e-175 583.3 0.0 7.1e-175 583.1 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 SIR2 PF02146.17 EPS32231.1 - 7.6e-30 104.1 0.0 1.5e-29 103.2 0.0 1.5 1 1 0 1 1 1 1 Sir2 family CBFD_NFYB_HMF PF00808.23 EPS32232.1 - 1.3e-05 25.4 0.0 3.1e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EPS32232.1 - 0.07 13.5 0.0 0.07 13.5 0.0 2.8 2 1 1 3 3 3 0 Core histone H2A/H2B/H3/H4 CDC27 PF09507.10 EPS32232.1 - 1.4 8.3 24.4 2.2 7.6 24.4 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Hid1 PF12722.7 EPS32232.1 - 1.5 6.8 8.4 1.8 6.6 8.4 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF5427 PF10310.9 EPS32232.1 - 1.7 7.5 20.5 3 6.7 20.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Paf1 PF03985.13 EPS32232.1 - 1.7 7.6 28.2 2.5 7.0 28.2 1.3 1 0 0 1 1 1 0 Paf1 Nop14 PF04147.12 EPS32232.1 - 6.8 4.8 41.7 8.7 4.4 41.7 1.1 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 EPS32232.1 - 7.7 5.2 14.7 9.7 4.8 14.7 1.2 1 0 0 1 1 1 0 Presenilin RR_TM4-6 PF06459.12 EPS32232.1 - 8.6 6.1 20.7 14 5.4 20.7 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GN3L_Grn1 PF08701.11 EPS32233.1 - 2.5e-23 82.0 18.0 2.5e-23 82.0 18.0 2.0 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 EPS32233.1 - 5.6e-19 68.3 1.1 2.8e-13 50.0 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EPS32233.1 - 1.6e-07 31.4 0.1 3.2e-06 27.1 0.1 2.3 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 EPS32233.1 - 2e-06 27.4 0.1 5e-05 22.9 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 EPS32233.1 - 9e-06 25.3 0.2 0.071 12.6 0.0 2.9 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EPS32233.1 - 9.9e-05 22.5 7.2 0.42 10.6 1.4 3.6 2 2 1 3 3 3 2 Dynamin family AIG1 PF04548.16 EPS32233.1 - 0.00094 18.6 0.3 0.28 10.5 0.1 2.4 2 0 0 2 2 2 2 AIG1 family NOG1 PF06858.14 EPS32233.1 - 0.0073 16.1 0.1 5.4 6.9 0.1 3.0 2 1 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) MeaB PF03308.16 EPS32233.1 - 0.028 13.4 0.0 0.028 13.4 0.0 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 EPS32233.1 - 0.06 12.8 0.0 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family cobW PF02492.19 EPS32233.1 - 0.066 12.8 0.1 0.58 9.7 0.0 2.3 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 EPS32233.1 - 0.071 13.3 0.0 18 5.5 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 EPS32233.1 - 0.21 12.2 0.0 0.21 12.2 0.0 2.7 2 1 1 3 3 2 0 AAA domain AAA_16 PF13191.6 EPS32233.1 - 0.46 10.9 0.0 0.46 10.9 0.0 3.2 2 1 0 2 2 1 0 AAA ATPase domain RRN3 PF05327.11 EPS32233.1 - 0.79 8.2 5.3 1.1 7.8 5.3 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 BUD22 PF09073.10 EPS32233.1 - 3.3 7.0 20.9 5.6 6.2 20.9 1.3 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.12 EPS32233.1 - 3.8 6.7 17.2 6.9 5.9 17.2 1.4 1 0 0 1 1 1 0 NOA36 protein HAD_2 PF13419.6 EPS32234.1 - 2.3e-19 70.2 0.0 3.4e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EPS32234.1 - 4.4e-07 30.4 0.1 0.00012 22.5 0.0 2.3 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EPS32234.1 - 0.0004 20.4 0.0 0.00072 19.6 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EPS32234.1 - 0.0036 17.7 0.0 0.0057 17.1 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase ADH_zinc_N PF00107.26 EPS32234.1 - 0.026 14.5 0.2 0.072 13.1 0.1 1.8 2 1 0 2 2 2 0 Zinc-binding dehydrogenase CdiI_3 PF18616.1 EPS32238.1 - 0.11 12.4 0.0 0.13 12.2 0.0 1.0 1 0 0 1 1 1 0 CDI immunity proteins Homeodomain PF00046.29 EPS32239.1 - 6.4e-17 61.2 2.4 1.5e-16 60.0 2.4 1.6 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EPS32239.1 - 4.2e-06 26.5 0.5 9.4e-06 25.4 0.5 1.6 1 0 0 1 1 1 1 Homeobox KN domain His_Phos_1 PF00300.22 EPS32240.1 - 1.3e-07 31.5 0.0 2.4e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Grg1 PF11034.8 EPS32242.1 - 1.7e-33 114.6 14.0 2e-33 114.4 14.0 1.0 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 Zn_Tnp_IS91 PF14319.6 EPS32243.1 - 0.85 9.7 4.2 0.29 11.2 0.6 1.8 1 1 1 2 2 2 0 Transposase zinc-binding domain Y_phosphatase3 PF13350.6 EPS32244.1 - 1.4e-51 175.7 0.0 2.7e-51 174.8 0.0 1.4 1 1 0 1 1 1 1 Tyrosine phosphatase family ALF PF03752.13 EPS32244.1 - 0.006 16.5 0.1 0.006 16.5 0.1 1.9 2 0 0 2 2 2 1 Short repeats of unknown function PTPlike_phytase PF14566.6 EPS32244.1 - 0.14 12.3 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase PF00102.27 EPS32244.1 - 0.21 11.1 0.0 0.28 10.7 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase polyprenyl_synt PF00348.17 EPS32245.1 - 3e-62 210.0 0.0 4.6e-62 209.4 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase Prenyltrans PF00432.21 EPS32245.1 - 0.00013 21.6 0.0 4.3 7.2 0.0 4.0 3 0 0 3 3 3 3 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 EPS32245.1 - 0.037 13.1 0.1 4 6.4 0.0 2.4 2 0 0 2 2 2 0 Squalene-hopene cyclase N-terminal domain p450 PF00067.22 EPS32246.1 - 2.3e-72 244.2 0.0 2.9e-72 243.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4538 PF15061.6 EPS32246.1 - 0.012 15.3 1.4 0.024 14.3 1.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) p450 PF00067.22 EPS32247.1 - 3e-71 240.5 0.0 3.9e-71 240.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 EPS32248.1 - 3e-34 118.2 0.0 4.2e-34 117.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS32248.1 - 4.9e-22 78.6 0.0 7.2e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPS32248.1 - 1.7e-10 41.1 0.8 2.3e-09 37.4 0.8 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EPS32248.1 - 3.5e-05 23.4 0.0 5.9e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family CRC_subunit PF08624.10 EPS32249.1 - 2.6e-51 173.6 0.0 5.9e-51 172.5 0.0 1.6 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit LAP1C PF05609.12 EPS32249.1 - 0.47 9.5 17.1 0.98 8.4 17.1 1.5 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Zip PF02535.22 EPS32249.1 - 2.3 7.3 4.0 3.7 6.7 4.0 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter NARP1 PF12569.8 EPS32249.1 - 5.1 5.9 10.1 7.6 5.3 10.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SERTA PF06031.13 EPS32251.1 - 0.088 12.5 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 SERTA motif Spem1 PF15670.5 EPS32251.1 - 0.14 11.7 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Spermatid maturation protein 1 TMF_TATA_bd PF12325.8 EPS32253.1 - 5e-39 133.1 10.7 5e-39 133.1 10.7 6.4 2 1 3 5 5 5 2 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 EPS32253.1 - 2.1e-09 37.2 13.7 2.1e-09 37.2 13.7 7.3 3 2 2 6 6 6 1 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 EPS32253.1 - 0.00031 21.0 4.1 0.00031 21.0 4.1 5.9 3 1 2 5 5 5 2 Autophagy protein 16 (ATG16) UPF0242 PF06785.11 EPS32253.1 - 0.014 15.5 5.3 0.014 15.5 5.3 4.7 2 1 2 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus Filament PF00038.21 EPS32253.1 - 0.016 14.8 77.8 3.6 7.1 49.0 4.0 2 1 1 3 3 3 0 Intermediate filament protein DUF4248 PF14053.6 EPS32253.1 - 0.53 10.4 6.4 0.24 11.5 0.7 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4248) HMMR_N PF15905.5 EPS32253.1 - 0.95 8.9 81.9 0.059 12.8 21.6 4.4 2 1 2 4 4 4 0 Hyaluronan mediated motility receptor N-terminal DUF5481 PF17578.2 EPS32253.1 - 9.9 6.6 7.9 0.29 11.6 0.5 2.3 3 0 0 3 3 3 0 Family of unknown function (DUF5481) V-ATPase_H_N PF03224.14 EPS32254.1 - 3.8e-82 276.1 0.0 6.8e-82 275.3 0.0 1.4 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 EPS32254.1 - 3.8e-38 130.2 0.3 4.6e-37 126.7 0.0 2.7 3 0 0 3 3 3 1 V-ATPase subunit H Arm PF00514.23 EPS32254.1 - 0.13 12.4 0.1 1.1 9.4 0.0 2.7 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Fungal_trans_2 PF11951.8 EPS32255.1 - 1.1e-59 202.3 3.4 1.3e-59 201.9 3.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS32255.1 - 4.3e-08 33.2 6.8 7.1e-08 32.5 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med3 PF11593.8 EPS32255.1 - 0.0067 15.7 9.3 0.01 15.1 9.3 1.2 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal Thy1 PF02511.15 EPS32255.1 - 0.049 13.4 0.1 0.13 12.1 0.1 1.7 1 0 0 1 1 1 0 Thymidylate synthase complementing protein APH PF01636.23 EPS32256.1 - 2.7e-07 30.8 0.0 3.4e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family GCV_T PF01571.21 EPS32257.1 - 2.9e-79 266.1 0.0 3.7e-79 265.7 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 EPS32257.1 - 9.8e-16 57.5 0.2 2.1e-15 56.4 0.2 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Aa_trans PF01490.18 EPS32258.1 - 9.9e-27 93.7 32.7 1.2e-26 93.4 32.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CBF PF03914.17 EPS32259.1 - 2.2e-54 184.0 0.0 2.2e-54 184.0 0.0 2.5 2 1 0 2 2 2 1 CBF/Mak21 family tRNA-synt_2b PF00587.25 EPS32260.1 - 2.2e-28 99.4 0.0 1.1e-27 97.1 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EPS32260.1 - 1.3e-13 50.9 0.0 2.8e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain Rod_C PF10493.9 EPS32260.1 - 0.002 16.6 0.0 0.0029 16.1 0.0 1.1 1 0 0 1 1 1 1 Rough deal protein C-terminal region Crystall PF00030.19 EPS32260.1 - 0.18 12.0 0.0 0.38 11.0 0.0 1.5 1 0 0 1 1 1 0 Beta/Gamma crystallin Prefoldin PF02996.17 EPS32261.1 - 1.8e-24 86.0 0.3 2.3e-24 85.6 0.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.20 EPS32261.1 - 0.033 14.1 0.7 0.92 9.5 0.3 2.1 2 0 0 2 2 2 0 Prefoldin subunit DUF1664 PF07889.12 EPS32261.1 - 0.13 12.4 0.5 5.7 7.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) KH_1 PF00013.29 EPS32262.1 - 0.071 13.0 0.0 0.26 11.1 0.0 2.0 1 0 0 1 1 1 0 KH domain PEPCK_N PF17297.2 EPS32262.1 - 0.18 11.4 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase N-terminal domain AAA PF00004.29 EPS32263.1 - 1.9e-15 57.5 0.0 3.6e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_10 PF17872.1 EPS32263.1 - 2.8e-12 46.6 0.8 2.8e-11 43.4 0.6 2.3 1 1 1 2 2 2 1 AAA lid domain AAA_22 PF13401.6 EPS32263.1 - 1.8e-09 38.0 0.0 4.3e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EPS32263.1 - 7.1e-09 36.3 0.4 3.8e-08 33.9 0.0 2.4 2 2 0 2 2 2 1 AAA ATPase domain BAH PF01426.18 EPS32263.1 - 8.1e-05 22.5 0.0 0.0002 21.2 0.0 1.6 1 0 0 1 1 1 1 BAH domain AAA_28 PF13521.6 EPS32263.1 - 0.003 17.8 0.6 0.007 16.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.6 EPS32263.1 - 0.0034 17.7 0.1 0.0084 16.5 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EPS32263.1 - 0.0043 17.2 0.0 0.1 12.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EPS32263.1 - 0.022 14.7 0.0 0.059 13.3 0.0 1.7 1 1 0 1 1 1 0 NACHT domain AAA_11 PF13086.6 EPS32263.1 - 0.028 14.2 0.0 0.028 14.2 0.0 2.1 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.6 EPS32263.1 - 0.033 14.7 0.0 0.095 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EPS32263.1 - 0.043 13.1 0.0 0.088 12.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.14 EPS32263.1 - 0.05 12.8 0.0 0.093 11.9 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase AAA_32 PF13654.6 EPS32263.1 - 0.05 12.4 0.0 0.088 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain ssDBP PF17878.1 EPS32263.1 - 0.059 13.6 0.0 0.26 11.5 0.0 2.0 2 0 0 2 2 2 0 Single-stranded DNA-binding protein Kinesin PF00225.23 EPS32263.1 - 0.065 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Kinesin motor domain ATPase_2 PF01637.18 EPS32263.1 - 0.12 12.3 0.0 1.9 8.4 0.0 2.2 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Hydin_ADK PF17213.3 EPS32263.1 - 0.74 10.1 6.8 16 5.7 0.0 3.7 4 0 0 4 4 4 0 Hydin Adenylate kinase-like domain HrpB7 PF09486.10 EPS32263.1 - 8.7 6.7 12.0 0.26 11.7 1.0 3.1 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) WD40 PF00400.32 EPS32264.1 - 5e-45 150.6 9.7 5.9e-09 36.4 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS32264.1 - 9.4e-06 25.8 0.2 3 8.2 0.1 4.8 1 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EPS32264.1 - 0.092 11.4 3.0 9.9 4.7 0.0 4.1 1 1 2 5 5 5 0 Nucleoporin Nup120/160 WD40_like PF17005.5 EPS32264.1 - 0.23 10.7 0.0 0.43 9.8 0.0 1.5 1 0 0 1 1 1 0 WD40-like domain Ank_2 PF12796.7 EPS32265.1 - 3.9e-52 174.8 0.6 6e-16 58.8 0.1 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EPS32265.1 - 8.4e-32 108.8 6.0 1.7e-09 37.7 0.1 4.6 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPS32265.1 - 6.2e-29 96.8 0.6 0.00052 20.3 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 EPS32265.1 - 3.8e-28 97.5 0.4 6.2e-10 39.4 0.1 4.3 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 EPS32265.1 - 7.6e-27 92.5 0.6 5.7e-06 26.5 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Shal-type PF11601.8 EPS32265.1 - 0.19 11.3 0.9 0.57 9.8 0.0 2.2 2 0 0 2 2 2 0 Shal-type voltage-gated potassium channels, N-terminal FMO-like PF00743.19 EPS32266.1 - 9.7e-20 70.5 0.1 1e-18 67.1 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EPS32266.1 - 2.2e-13 50.2 0.0 4.9e-12 45.7 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EPS32266.1 - 1.1e-11 44.5 0.0 6.3e-10 38.8 0.0 2.7 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EPS32266.1 - 3.3e-10 39.6 0.1 8.8e-07 28.4 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EPS32266.1 - 2.9e-07 30.6 0.0 7.3e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EPS32266.1 - 1.3e-05 25.0 0.0 0.00054 19.7 0.0 2.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 EPS32266.1 - 5.3e-05 23.3 0.0 0.18 11.9 0.0 2.5 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.17 EPS32266.1 - 0.00048 19.4 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 EPS32266.1 - 0.00078 20.0 0.0 0.99 10.0 0.0 3.0 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EPS32266.1 - 0.0012 18.8 0.0 0.018 15.0 0.0 2.9 4 0 0 4 4 4 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 EPS32266.1 - 0.0071 16.8 0.0 1.2 9.6 0.0 2.8 2 1 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.24 EPS32266.1 - 0.036 13.2 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.14 EPS32266.1 - 0.21 10.3 0.2 0.35 9.5 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein Filament PF00038.21 EPS32267.1 - 0.00015 21.5 4.7 0.00015 21.5 4.7 6.9 5 1 1 6 6 6 2 Intermediate filament protein DUF2533 PF10752.9 EPS32267.1 - 0.0051 17.2 0.9 0.041 14.3 0.9 2.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2533) MatP_C PF17414.2 EPS32267.1 - 0.033 14.4 5.2 0.061 13.5 2.6 3.0 2 1 0 2 2 2 0 MatP C-terminal ribbon-helix-helix domain Apq12 PF12716.7 EPS32268.1 - 5.9e-19 67.8 24.6 7.6e-18 64.2 24.6 2.2 1 1 0 1 1 1 1 Nuclear pore assembly and biogenesis ATP_bind_1 PF03029.17 EPS32269.1 - 5.8e-77 258.7 0.1 6.6e-77 258.5 0.1 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 EPS32269.1 - 9.5e-05 22.8 0.0 0.00051 20.5 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain CLP1_P PF16575.5 EPS32269.1 - 0.00025 20.9 0.0 0.0008 19.3 0.0 1.8 2 0 0 2 2 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_14 PF13173.6 EPS32269.1 - 0.00049 20.1 0.0 0.0013 18.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 EPS32269.1 - 0.0014 17.7 0.0 0.0028 16.8 0.0 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_33 PF13671.6 EPS32269.1 - 0.0021 18.2 0.0 0.0037 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EPS32269.1 - 0.0027 18.1 0.4 0.15 12.4 0.0 2.2 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EPS32269.1 - 0.0051 16.7 0.1 0.18 11.7 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 EPS32269.1 - 0.0058 17.2 0.0 0.014 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EPS32269.1 - 0.007 16.7 0.0 0.018 15.4 0.0 1.7 1 0 0 1 1 1 1 RNA helicase CbiA PF01656.23 EPS32269.1 - 0.0079 16.2 0.0 0.0098 15.9 0.0 1.3 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain GTP_EFTU PF00009.27 EPS32269.1 - 0.013 15.1 0.1 4.2 6.9 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 EPS32269.1 - 0.013 15.8 0.0 0.033 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EPS32269.1 - 0.015 14.9 0.0 0.031 13.8 0.0 1.6 2 0 0 2 2 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EPS32269.1 - 0.015 15.0 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EPS32269.1 - 0.015 15.7 0.0 0.036 14.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_31 PF13614.6 EPS32269.1 - 0.02 14.8 0.0 7.4 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EPS32269.1 - 0.02 14.6 0.0 0.084 12.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EPS32269.1 - 0.025 14.6 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 EPS32269.1 - 0.028 14.1 0.0 0.048 13.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain MMR_HSR1 PF01926.23 EPS32269.1 - 0.031 14.4 0.0 0.067 13.3 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase Septin PF00735.18 EPS32269.1 - 0.036 13.3 0.0 0.06 12.6 0.0 1.3 1 0 0 1 1 1 0 Septin ArsA_ATPase PF02374.15 EPS32269.1 - 0.038 13.2 0.0 0.083 12.1 0.0 1.5 1 0 0 1 1 1 0 Anion-transporting ATPase ATPase PF06745.13 EPS32269.1 - 0.038 13.3 0.0 0.1 11.9 0.0 1.7 1 0 0 1 1 1 0 KaiC NACHT PF05729.12 EPS32269.1 - 0.043 13.7 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 EPS32269.1 - 0.043 14.3 0.0 0.12 12.9 0.0 1.7 2 0 0 2 2 1 0 ABC transporter cobW PF02492.19 EPS32269.1 - 0.056 13.0 0.2 0.79 9.3 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.22 EPS32269.1 - 0.063 12.4 0.3 0.33 10.1 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_5 PF07728.14 EPS32269.1 - 0.076 13.0 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SRP54 PF00448.22 EPS32269.1 - 0.086 12.5 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ATPase_2 PF01637.18 EPS32269.1 - 0.09 12.7 0.0 0.22 11.4 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Sigma54_activ_2 PF14532.6 EPS32269.1 - 0.1 12.7 0.0 0.31 11.2 0.0 1.8 2 0 0 2 2 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 EPS32269.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein KAP_NTPase PF07693.14 EPS32269.1 - 0.12 11.6 0.0 0.25 10.5 0.0 1.7 1 1 0 1 1 1 0 KAP family P-loop domain Thymidylate_kin PF02223.17 EPS32269.1 - 0.12 12.1 0.0 0.31 10.7 0.0 1.7 2 0 0 2 2 1 0 Thymidylate kinase KTI12 PF08433.10 EPS32269.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 EPS32269.1 - 0.13 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.6 EPS32269.1 - 0.15 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain APS_kinase PF01583.20 EPS32269.1 - 0.18 11.7 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase S-AdoMet_synt_C PF02773.16 EPS32270.1 - 4.5e-67 224.3 0.4 2e-66 222.2 0.1 2.0 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_N PF00438.20 EPS32270.1 - 1.3e-44 150.9 1.2 1.7e-44 150.5 0.2 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_M PF02772.16 EPS32270.1 - 1.4e-43 147.9 0.0 3.2e-43 146.8 0.0 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain Lactamase_B_3 PF13483.6 EPS32270.1 - 0.084 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain DUF2312 PF10073.9 EPS32270.1 - 0.15 11.8 0.1 0.45 10.2 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) GMC_oxred_N PF00732.19 EPS32272.1 - 3.1e-69 233.6 0.0 3.9e-69 233.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EPS32272.1 - 7.8e-39 133.5 0.0 1.3e-38 132.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EPS32272.1 - 2.8e-05 24.3 0.3 7.2e-05 22.9 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EPS32272.1 - 0.00013 21.1 1.3 0.012 14.7 0.6 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.12 EPS32272.1 - 0.0002 20.6 0.0 0.0003 20.0 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EPS32272.1 - 0.0012 18.2 0.0 0.0025 17.1 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EPS32272.1 - 0.0041 16.8 0.4 0.0093 15.6 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EPS32272.1 - 0.019 13.7 0.1 0.028 13.1 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 EPS32272.1 - 0.03 13.6 0.2 0.074 12.3 0.2 1.6 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.16 EPS32272.1 - 0.054 13.1 0.1 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 EPS32272.1 - 0.12 11.6 0.2 0.27 10.4 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.21 EPS32272.1 - 0.18 11.1 0.0 0.33 10.3 0.0 1.4 1 0 0 1 1 1 0 ThiF family Pyr_redox PF00070.27 EPS32272.1 - 0.21 12.2 0.3 0.67 10.6 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SLD3 PF08639.10 EPS32273.1 - 1.7e-166 555.1 2.0 1.7e-166 555.1 2.0 1.4 2 0 0 2 2 2 1 DNA replication regulator SLD3 TEX13 PF15186.6 EPS32273.1 - 0.03 14.0 0.5 0.077 12.7 0.5 1.6 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family Glyco_hydro_92 PF07971.12 EPS32274.1 - 2.3e-145 485.1 0.3 2.7e-145 484.8 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EPS32274.1 - 3.7e-63 213.6 0.0 6.3e-63 212.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain 4HBT PF03061.22 EPS32275.1 - 1.7e-11 44.3 0.0 4.2e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily APS_kinase PF01583.20 EPS32276.1 - 4.4e-70 234.6 0.0 5.7e-70 234.3 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 EPS32276.1 - 2e-06 28.0 0.0 4.1e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EPS32276.1 - 7.7e-05 23.3 0.0 0.00012 22.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EPS32276.1 - 0.00047 20.6 0.0 0.0005 20.5 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.10 EPS32276.1 - 0.008 15.7 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 EPS32276.1 - 0.032 13.5 0.0 0.14 11.4 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin G-alpha PF00503.20 EPS32276.1 - 0.05 12.7 0.1 0.082 12.1 0.1 1.7 1 1 0 1 1 1 0 G-protein alpha subunit AAA_29 PF13555.6 EPS32276.1 - 0.097 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain V-ATPase_C PF03223.15 EPS32277.1 - 6.1e-129 430.6 0.0 6.8e-129 430.5 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C RhoGAP PF00620.27 EPS32278.1 - 4.4e-47 159.7 0.0 1.3e-46 158.2 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 EPS32278.1 - 2.2e-14 53.4 17.7 1.1e-09 38.4 1.7 2.4 2 0 0 2 2 2 2 LIM domain DZR PF12773.7 EPS32278.1 - 0.0015 18.5 12.1 4.1 7.5 6.1 4.1 1 1 2 3 3 3 1 Double zinc ribbon CENP-H PF05837.12 EPS32278.1 - 0.035 14.5 0.7 0.035 14.5 0.7 3.2 2 1 1 3 3 3 0 Centromere protein H (CENP-H) TMF_TATA_bd PF12325.8 EPS32278.1 - 0.19 11.9 17.8 2.6 8.3 2.3 3.6 3 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF4407 PF14362.6 EPS32278.1 - 0.65 9.3 7.4 0.12 11.7 1.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Rab5-bind PF09311.11 EPS32278.1 - 0.88 8.9 11.2 2.8 7.3 1.7 2.5 2 0 0 2 2 2 0 Rabaptin-like protein Fez1 PF06818.15 EPS32278.1 - 2.2 8.7 10.8 5.4 7.4 10.8 1.7 1 0 0 1 1 1 0 Fez1 Zn-ribbon_8 PF09723.10 EPS32278.1 - 4.9 7.4 19.8 0.86 9.8 1.6 3.9 3 1 1 4 4 4 0 Zinc ribbon domain DUF3450 PF11932.8 EPS32278.1 - 6 6.1 10.1 0.19 11.0 2.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) zf-ribbon_3 PF13248.6 EPS32278.1 - 7.2 6.2 17.1 1.9 8.0 0.0 4.4 5 1 0 5 5 5 0 zinc-ribbon domain DUF4164 PF13747.6 EPS32278.1 - 7.8 6.9 9.9 0.41 11.0 1.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) OmpH PF03938.14 EPS32278.1 - 8.3 6.8 10.7 44 4.4 10.1 2.2 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DHquinase_I PF01487.15 EPS32279.1 - 4.2e-36 125.3 0.0 6.5e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.11 EPS32279.1 - 3.9e-22 78.3 0.0 8.7e-22 77.2 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.22 EPS32279.1 - 1.3e-16 61.1 0.1 3e-16 59.9 0.0 1.6 2 0 0 2 2 2 1 Shikimate kinase SDH_C PF18317.1 EPS32279.1 - 6.9e-10 38.5 0.1 1.5e-09 37.4 0.1 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 EPS32279.1 - 1e-07 32.1 0.1 3.2e-07 30.5 0.1 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase AAA_33 PF13671.6 EPS32279.1 - 0.00042 20.5 0.0 0.001 19.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain F420_oxidored PF03807.17 EPS32279.1 - 0.0017 18.9 0.0 0.034 14.7 0.0 2.6 2 1 1 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent AAA_16 PF13191.6 EPS32279.1 - 0.014 15.8 0.1 0.071 13.5 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 EPS32279.1 - 0.036 14.6 0.0 0.068 13.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DUF815 PF05673.13 EPS32279.1 - 0.11 11.6 0.1 0.19 10.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Fungal_trans PF04082.18 EPS32280.1 - 1.9e-15 56.6 1.3 2.7e-15 56.1 0.4 1.6 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS32280.1 - 1.8e-09 37.5 13.2 2.9e-09 36.9 13.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHquinase_II PF01220.19 EPS32282.1 - 2e-63 212.2 0.0 2.3e-63 212.0 0.0 1.0 1 0 0 1 1 1 1 Dehydroquinase class II Inositol_P PF00459.25 EPS32283.1 - 1.7e-81 273.7 0.0 1.9e-81 273.5 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Shikimate_dh_N PF08501.11 EPS32284.1 - 4.8e-22 78.0 0.0 1.5e-21 76.4 0.0 1.8 1 1 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 EPS32284.1 - 0.00016 21.4 0.1 0.00036 20.3 0.1 1.7 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain B12-binding PF02310.19 EPS32284.1 - 0.06 13.4 0.0 7.5 6.6 0.0 2.7 2 0 0 2 2 2 0 B12 binding domain Shikimate_DH PF01488.20 EPS32284.1 - 0.092 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sugar_tr PF00083.24 EPS32285.1 - 3.4e-140 467.9 23.4 3.8e-140 467.7 23.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS32285.1 - 8.9e-23 80.8 42.3 1.8e-22 79.8 38.4 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily AP_endonuc_2 PF01261.24 EPS32286.1 - 1e-31 110.1 0.0 1.2e-31 109.8 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Choline_kinase PF01633.20 EPS32287.1 - 3e-43 147.9 0.0 3e-42 144.6 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 EPS32287.1 - 2.1e-07 31.1 0.6 2.1e-07 31.1 0.6 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 EPS32287.1 - 0.03 13.6 0.0 0.073 12.4 0.0 1.5 1 1 0 1 1 1 0 Ecdysteroid kinase CHORD PF04968.12 EPS32288.1 - 1.1e-51 173.3 17.9 3.8e-27 94.8 4.7 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.16 EPS32288.1 - 2.5e-14 54.0 0.1 3.7e-14 53.5 0.1 1.3 1 0 0 1 1 1 1 CS domain BTK PF00779.19 EPS32288.1 - 0.16 11.8 10.2 1.8 8.4 0.7 3.5 3 0 0 3 3 3 0 BTK motif peroxidase PF00141.23 EPS32289.1 - 5e-84 281.6 0.0 1.5e-42 145.9 0.0 2.2 2 0 0 2 2 2 2 Peroxidase Zn_clus PF00172.18 EPS32290.1 - 5.1e-09 36.1 6.8 8.8e-09 35.4 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EPS32290.1 - 1.1e-07 31.0 0.0 1.8e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Opy2 PF09463.10 EPS32290.1 - 5.1 7.5 6.2 0.86 10.0 2.1 1.8 2 0 0 2 2 2 0 Opy2 protein RTA1 PF04479.13 EPS32291.1 - 3.7e-59 199.8 7.7 5.3e-59 199.3 7.7 1.2 1 0 0 1 1 1 1 RTA1 like protein Abhydrolase_9_N PF15420.6 EPS32291.1 - 0.93 9.4 8.5 0.23 11.4 3.3 2.3 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus Fungal_trans PF04082.18 EPS32294.1 - 6.4e-15 54.9 0.1 1.4e-14 53.8 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 EPS32295.1 - 1.5e-19 70.2 62.9 6.3e-18 64.8 58.5 3.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS32295.1 - 8.7e-10 38.0 13.8 8.7e-10 38.0 13.8 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter DUF4757 PF15949.5 EPS32295.1 - 0.28 11.7 0.0 0.39 11.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4757) PhyH PF05721.13 EPS32296.1 - 1.1e-05 25.8 0.4 0.00015 22.1 0.4 2.1 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Sugar_tr PF00083.24 EPS32297.1 - 1.2e-82 278.2 17.9 1.4e-82 278.0 17.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS32297.1 - 3.4e-33 115.0 44.3 1.3e-30 106.6 22.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EPS32297.1 - 0.00012 20.8 0.7 0.00012 20.8 0.7 2.6 3 0 0 3 3 3 2 MFS/sugar transport protein OATP PF03137.20 EPS32297.1 - 0.037 12.3 0.1 0.037 12.3 0.1 2.5 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Tad PF13400.6 EPS32297.1 - 0.16 12.3 2.0 14 6.1 0.7 2.9 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like Ferritin_2 PF13668.6 EPS32298.1 - 6.5e-08 32.9 0.0 1e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain Epsilon_antitox PF08998.11 EPS32298.1 - 0.13 12.5 0.3 0.24 11.7 0.3 1.4 1 0 0 1 1 1 0 Bacterial epsilon antitoxin Pec_lyase_C PF00544.19 EPS32299.1 - 1.6e-16 60.5 12.3 4.5e-15 55.8 12.3 2.3 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.6 EPS32299.1 - 4.3e-07 29.9 29.9 8.6e-06 25.7 16.3 2.0 1 1 1 2 2 2 2 Right handed beta helix region Amidase PF01425.21 EPS32301.1 - 2.7e-71 240.9 0.2 1.6e-66 225.2 0.0 2.1 2 0 0 2 2 2 2 Amidase NmrA PF05368.13 EPS32303.1 - 1.9e-15 57.1 0.1 2.7e-15 56.6 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPS32303.1 - 9.5e-13 48.4 0.0 1.5e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EPS32303.1 - 8.1e-05 22.6 0.0 0.0096 15.8 0.0 2.4 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 EPS32303.1 - 0.0014 18.1 0.0 0.0045 16.5 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EPS32303.1 - 0.0046 16.0 0.0 0.0071 15.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 EPS32303.1 - 0.029 13.8 0.0 0.16 11.4 0.0 2.0 1 1 1 2 2 2 0 short chain dehydrogenase Fer2_3 PF13085.6 EPS32304.1 - 5.3e-31 106.9 0.0 8.2e-31 106.2 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 EPS32304.1 - 1.4e-08 35.1 5.8 1.4e-08 35.1 5.8 2.2 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 EPS32304.1 - 4.1e-07 30.0 3.8 4.1e-07 30.0 3.8 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EPS32304.1 - 6.4e-07 29.7 7.4 6.4e-07 29.7 7.4 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 EPS32304.1 - 0.0031 18.0 4.9 0.0031 18.0 4.9 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 EPS32304.1 - 0.0097 15.8 0.3 0.0097 15.8 0.3 2.3 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.6 EPS32304.1 - 0.68 10.1 12.4 1.4 9.1 9.2 2.7 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 EPS32304.1 - 5.7 7.2 8.4 1.1 9.4 0.2 2.6 3 0 0 3 3 3 0 4Fe-4S dicluster domain Methyltransf_2 PF00891.18 EPS32305.1 - 2.1e-09 37.0 0.1 3.6e-09 36.2 0.1 1.3 1 0 0 1 1 1 1 O-methyltransferase domain SnoaL_4 PF13577.6 EPS32305.1 - 1e-07 32.1 0.0 1.5e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain Methyltransf_2 PF00891.18 EPS32306.1 - 0.0016 17.8 0.0 0.0019 17.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain F_bP_aldolase PF01116.20 EPS32308.1 - 6.1e-87 291.6 0.1 6.9e-87 291.5 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Methyltransf_24 PF13578.6 EPS32308.1 - 0.083 13.9 0.1 0.14 13.2 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_11 PF14833.6 EPS32309.1 - 1.2e-40 138.6 4.9 4e-29 101.3 0.0 2.2 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.15 EPS32309.1 - 2.3e-37 128.6 0.1 2.3e-37 128.6 0.1 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 EPS32309.1 - 0.00016 21.6 0.5 0.00033 20.6 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EPS32309.1 - 0.0058 17.2 0.2 0.029 15.0 0.0 2.4 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent DUF1451 PF07295.11 EPS32309.1 - 0.014 15.5 0.2 0.028 14.5 0.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon containing domain DUF3337 PF11816.8 EPS32311.1 - 0.053 13.4 0.0 0.073 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) Aldo_ket_red PF00248.21 EPS32312.1 - 9.9e-40 136.6 0.0 1.6e-37 129.3 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family DNApol_Exo PF18136.1 EPS32312.1 - 0.028 13.6 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain AbiEii PF08843.11 EPS32313.1 - 0.051 13.5 0.5 0.21 11.5 0.5 1.9 1 1 0 1 1 1 0 Nucleotidyl transferase AbiEii toxin, Type IV TA system Stimulus_sens_1 PF13756.6 EPS32315.1 - 0.13 12.8 0.0 0.15 12.7 0.0 1.1 1 0 0 1 1 1 0 Stimulus-sensing domain Glyco_hydro_92 PF07971.12 EPS32316.1 - 1.1e-140 469.7 0.7 1.3e-140 469.4 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EPS32316.1 - 2.7e-51 174.8 1.2 3.9e-51 174.2 1.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain Alpha-amylase_C PF02806.18 EPS32318.1 - 8.5e-26 90.3 0.0 2.1e-25 89.0 0.0 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 EPS32318.1 - 5.1e-20 71.6 0.1 1.1e-19 70.5 0.1 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 EPS32318.1 - 6.8e-15 55.5 0.0 2.1e-11 44.0 0.1 2.3 1 1 1 2 2 2 2 Alpha amylase, catalytic domain ATP-synt_ab PF00006.25 EPS32319.1 - 4e-62 209.7 0.0 6.7e-62 208.9 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EPS32319.1 - 1.4e-22 79.9 2.4 3.9e-22 78.6 0.9 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain ATPase PF06745.13 EPS32319.1 - 0.0066 15.8 0.2 0.011 15.1 0.2 1.4 1 0 0 1 1 1 1 KaiC NB-ARC PF00931.22 EPS32319.1 - 0.019 14.2 0.3 0.1 11.8 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.29 EPS32319.1 - 0.019 15.4 0.0 1.3 9.5 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EPS32319.1 - 0.037 13.9 0.1 0.097 12.6 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_19 PF13245.6 EPS32319.1 - 0.039 14.3 0.7 0.44 10.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain RraA-like PF03737.15 EPS32319.1 - 0.042 14.0 0.1 0.1 12.8 0.1 1.6 1 0 0 1 1 1 0 Aldolase/RraA ATPase_2 PF01637.18 EPS32319.1 - 0.044 13.7 0.0 0.13 12.2 0.0 1.7 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea T3SS_ATPase_C PF18269.1 EPS32319.1 - 0.05 13.5 0.9 0.2 11.5 0.9 1.9 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain NACHT PF05729.12 EPS32319.1 - 0.056 13.4 0.2 0.13 12.1 0.0 1.6 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.22 EPS32319.1 - 0.12 12.8 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase DUF4618 PF15397.6 EPS32319.1 - 0.18 11.2 0.0 0.28 10.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) COX4 PF02936.14 EPS32320.1 - 2.7e-47 160.3 1.0 3.2e-47 160.0 1.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF3106 PF11304.8 EPS32320.1 - 0.043 14.3 3.6 0.043 14.3 3.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) DUF1104 PF06518.11 EPS32320.1 - 0.079 13.3 0.6 0.11 12.9 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) Cofilin_ADF PF00241.20 EPS32321.1 - 1.2e-35 121.9 0.0 1.4e-35 121.7 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SpoVR PF04293.13 EPS32321.1 - 0.04 12.6 0.1 0.05 12.3 0.1 1.1 1 0 0 1 1 1 0 SpoVR like protein GST_N_3 PF13417.6 EPS32322.1 - 5.3e-16 58.8 0.0 9.5e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EPS32322.1 - 7.4e-16 58.3 0.0 1.3e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EPS32322.1 - 1e-14 54.6 0.0 1.8e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 EPS32322.1 - 1.8e-05 25.3 0.0 3.4e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 EPS32322.1 - 4.1e-05 23.7 0.0 8.2e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_C_2 PF13410.6 EPS32322.1 - 0.00087 19.3 0.0 0.0018 18.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain CdiI_2 PF18593.1 EPS32322.1 - 0.11 13.2 0.0 0.29 11.8 0.0 1.6 1 0 0 1 1 1 0 CdiI immunity protein SH3_9 PF14604.6 EPS32323.1 - 1.4e-05 24.8 0.1 2.8e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EPS32323.1 - 0.00034 20.2 0.1 0.00077 19.0 0.1 1.6 1 0 0 1 1 1 1 SH3 domain Podoplanin PF05808.11 EPS32323.1 - 0.018 15.2 0.0 0.031 14.4 0.0 1.3 1 0 0 1 1 1 0 Podoplanin PTP_tm PF18861.1 EPS32323.1 - 0.023 14.7 0.6 0.046 13.7 0.6 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J DUF4690 PF15756.5 EPS32323.1 - 0.035 14.7 0.5 0.095 13.3 0.5 1.7 1 0 0 1 1 1 0 Small Novel Rich in Cartilage DUF4231 PF14015.6 EPS32323.1 - 0.41 11.1 1.0 1 9.9 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) SKG6 PF08693.10 EPS32323.1 - 2.6 7.5 5.2 6.3 6.3 5.2 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Pmp3 PF01679.17 EPS32324.1 - 6.1e-19 68.0 12.3 7.8e-19 67.6 12.3 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator She9_MDM33 PF05546.11 EPS32325.1 - 9.2e-87 290.0 9.2 1.3e-86 289.5 9.2 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family PsbH PF00737.20 EPS32325.1 - 0.075 12.8 0.8 0.15 11.8 0.8 1.4 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein GvpL_GvpF PF06386.11 EPS32325.1 - 3.5 7.5 8.5 11 5.9 8.4 1.9 1 1 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF UCR_TM PF02921.14 EPS32326.1 - 1.3e-11 44.8 0.6 3.6e-11 43.4 0.6 1.8 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.26 EPS32326.1 - 2.9e-11 43.1 0.0 5.4e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain CBFD_NFYB_HMF PF00808.23 EPS32327.1 - 9.5e-15 54.6 0.4 9.5e-15 54.6 0.4 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EPS32327.1 - 6.4e-05 23.3 2.8 6.6e-05 23.3 0.1 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Pol_alpha_B_N PF08418.10 EPS32327.1 - 0.017 15.1 0.3 0.019 15.0 0.3 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Voltage_CLC PF00654.20 EPS32328.1 - 1.3e-89 300.9 29.6 1.3e-89 300.9 29.6 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EPS32328.1 - 2.8e-12 46.9 0.0 2.3e-05 24.7 0.0 2.7 2 0 0 2 2 2 2 CBS domain FixP_N PF14715.6 EPS32328.1 - 0.13 12.1 0.1 0.13 12.1 0.1 3.3 4 0 0 4 4 4 0 N-terminal domain of cytochrome oxidase-cbb3, FixP EamA PF00892.20 EPS32329.1 - 7.5e-06 26.2 13.8 0.00016 21.9 13.8 2.0 1 1 0 1 1 1 1 EamA-like transporter family TMEM234 PF10639.9 EPS32329.1 - 0.025 14.6 1.2 0.03 14.3 1.2 1.3 1 0 0 1 1 1 0 Putative transmembrane family 234 PNP_phzG_C PF10590.9 EPS32330.1 - 6.1e-20 71.0 2.9 6.1e-20 71.0 2.9 2.5 3 1 1 4 4 4 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 EPS32330.1 - 2.3e-07 30.9 0.1 0.0042 17.3 0.0 2.6 3 0 0 3 3 3 2 Pyridoxamine 5'-phosphate oxidase ThiJ_like PF17124.5 EPS32332.1 - 3.9e-14 52.8 0.0 5.3e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 ThiJ/PfpI family-like DJ-1_PfpI PF01965.24 EPS32332.1 - 1.4e-13 51.0 0.0 3.7e-13 49.6 0.0 1.7 1 1 0 1 1 1 1 DJ-1/PfpI family Glyco_transf_4 PF13439.6 EPS32332.1 - 0.054 13.5 0.0 0.24 11.4 0.0 1.8 1 1 0 1 1 1 0 Glycosyltransferase Family 4 PPR_2 PF13041.6 EPS32333.1 - 3.3e-45 152.1 2.6 2.3e-09 37.3 0.0 12.5 11 4 4 15 15 15 9 PPR repeat family PPR_3 PF13812.6 EPS32333.1 - 2e-30 104.7 0.8 0.0037 17.3 0.0 10.9 7 4 3 11 11 11 7 Pentatricopeptide repeat domain PPR PF01535.20 EPS32333.1 - 5.3e-24 82.7 14.1 0.0011 19.0 0.0 13.3 14 1 0 14 14 14 5 PPR repeat PPR_1 PF12854.7 EPS32333.1 - 3e-21 74.8 0.0 1.7e-05 24.4 0.1 9.3 10 0 0 10 10 10 4 PPR repeat PPR_long PF17177.4 EPS32333.1 - 4.5e-17 62.1 16.8 1.7e-09 37.4 0.1 6.9 5 1 0 6 6 6 4 Pentacotripeptide-repeat region of PRORP RPM2 PF08579.11 EPS32333.1 - 3e-07 30.9 0.0 0.00075 19.9 0.0 4.6 5 0 0 5 5 5 1 Mitochondrial ribonuclease P subunit (RPM2) DUF4129 PF13559.6 EPS32333.1 - 0.31 11.3 2.1 0.81 10.0 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4129) TPR_7 PF13176.6 EPS32333.1 - 3.1 8.0 7.5 17 5.7 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat GHMP_kinases_N PF00288.26 EPS32335.1 - 1.2e-14 54.3 4.5 3e-14 53.0 4.5 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EPS32335.1 - 3e-09 37.1 0.0 9.3e-09 35.5 0.0 1.9 1 1 0 1 1 1 1 GHMP kinases C terminal DUF4763 PF15960.5 EPS32335.1 - 0.029 13.7 0.9 0.044 13.1 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Rad60-SLD_2 PF13881.6 EPS32336.1 - 1.1e-11 44.8 0.0 2e-11 44.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EPS32336.1 - 0.0037 17.8 0.0 0.0084 16.7 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.23 EPS32336.1 - 0.047 13.4 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin family UMP1 PF05348.11 EPS32337.1 - 3.6e-38 130.4 0.0 7e-38 129.5 0.0 1.5 1 1 0 1 1 1 1 Proteasome maturation factor UMP1 Ribosom_S12_S23 PF00164.25 EPS32338.1 - 2.9e-28 97.7 1.5 4.4e-28 97.2 1.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Glyco_transf_15 PF01793.16 EPS32339.1 - 8.1e-127 422.9 10.7 1e-126 422.7 10.7 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PAT1 PF09770.9 EPS32340.1 - 0 1164.6 6.9 7.2e-280 931.1 0.1 2.0 1 1 0 2 2 2 2 Topoisomerase II-associated protein PAT1 GDP_Man_Dehyd PF16363.5 EPS32342.1 - 2.5e-50 171.8 0.0 7.5e-50 170.2 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EPS32342.1 - 9.8e-48 162.7 0.0 1.5e-47 162.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EPS32342.1 - 1.7e-17 63.3 0.0 3.1e-17 62.5 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EPS32342.1 - 8.8e-13 48.0 0.1 1.5e-11 44.0 0.0 2.2 2 1 0 3 3 3 1 Polysaccharide biosynthesis protein adh_short PF00106.25 EPS32342.1 - 8.6e-12 44.9 0.0 2.1e-11 43.6 0.1 1.5 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 EPS32342.1 - 3.2e-11 42.9 0.0 4.6e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 EPS32342.1 - 7.3e-08 32.5 0.0 1.2e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 EPS32342.1 - 1.6e-05 24.2 0.0 9.9e-05 21.6 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein adh_short_C2 PF13561.6 EPS32342.1 - 3.6e-05 23.4 0.1 7.3e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EPS32342.1 - 4.9e-05 23.3 0.0 7.8e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EPS32342.1 - 0.012 15.1 0.1 0.028 14.0 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family Cys_Met_Meta_PP PF01053.20 EPS32342.1 - 0.13 10.7 0.2 0.22 10.0 0.0 1.4 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme adh_short PF00106.25 EPS32343.1 - 5.1e-15 55.5 0.0 3.4e-13 49.5 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EPS32343.1 - 9.7e-07 28.9 0.0 1.8e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EPS32343.1 - 3.1e-05 23.7 0.0 6.5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EPS32343.1 - 0.00022 20.8 0.0 0.00042 19.9 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EPS32343.1 - 0.054 13.0 0.0 0.095 12.2 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family G-patch PF01585.23 EPS32344.1 - 1.9e-05 24.4 0.4 3.6e-05 23.5 0.4 1.4 1 0 0 1 1 1 1 G-patch domain His_Phos_1 PF00300.22 EPS32345.1 - 2.3e-38 131.9 0.3 2.8e-38 131.6 0.3 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) HA2 PF04408.23 EPS32346.1 - 6.6e-24 84.3 1.4 9.7e-24 83.7 0.1 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EPS32346.1 - 5.1e-21 74.8 0.0 1.3e-20 73.5 0.0 1.7 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EPS32346.1 - 2.8e-14 53.4 0.0 6.7e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 EPS32346.1 - 4e-10 39.9 0.9 1.1e-09 38.5 0.9 1.7 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.29 EPS32346.1 - 5e-05 23.1 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EPS32346.1 - 0.00051 20.3 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EPS32346.1 - 0.00059 19.0 0.0 0.0013 17.9 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 EPS32346.1 - 0.0057 16.4 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EPS32346.1 - 0.02 15.2 0.0 0.041 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EPS32346.1 - 0.028 13.6 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 EPS32346.1 - 0.03 14.5 0.0 0.47 10.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EPS32346.1 - 0.097 13.1 0.0 0.29 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Microtub_bd PF16796.5 EPS32346.1 - 0.16 11.9 0.0 14 5.6 0.0 2.5 2 0 0 2 2 2 0 Microtubule binding SUV3_C PF12513.8 EPS32347.1 - 4.6e-16 58.5 0.1 8.6e-16 57.6 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 EPS32347.1 - 3e-09 37.2 0.0 6.6e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Suv3_C_1 PF18147.1 EPS32347.1 - 0.00098 18.9 0.0 0.002 18.0 0.0 1.5 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 DUF4771 PF15995.5 EPS32347.1 - 0.077 13.2 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4771) Sec1 PF00995.23 EPS32348.1 - 2.2e-111 373.9 0.0 2.9e-111 373.5 0.0 1.1 1 0 0 1 1 1 1 Sec1 family Npa1 PF11707.8 EPS32349.1 - 2.8e-96 322.9 0.1 2.8e-96 322.9 0.1 2.3 3 0 0 3 3 3 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 EPS32349.1 - 1.6e-56 191.1 0.0 6.2e-56 189.2 0.0 2.1 1 0 0 1 1 1 1 Nucleolar pre-ribosomal-associated protein 1 CM_1 PF07736.11 EPS32352.1 - 0.056 13.8 0.3 0.099 13.0 0.3 1.3 1 0 0 1 1 1 0 Chorismate mutase type I UCH PF00443.29 EPS32354.1 - 1.5e-34 119.7 0.0 2.7e-34 118.9 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EPS32354.1 - 4.7e-08 33.0 0.6 3.8e-07 30.0 0.6 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Alb1 PF09135.11 EPS32355.1 - 4.3e-31 107.9 16.1 7.7e-31 107.1 16.1 1.4 1 0 0 1 1 1 1 Alb1 XRN_M PF17846.1 EPS32355.1 - 4.1 6.2 7.4 5.4 5.9 7.4 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Spt5_N PF11942.8 EPS32355.1 - 6.6 7.8 12.3 16 6.6 4.5 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Vps16_N PF04841.13 EPS32356.1 - 3.3e-96 322.6 0.0 4.2e-96 322.2 0.0 1.1 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 EPS32356.1 - 5e-86 288.7 0.2 6.9e-86 288.2 0.2 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region ANAPC4_WD40 PF12894.7 EPS32356.1 - 0.00018 21.7 0.0 1.4 9.3 0.0 2.8 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain TruB_C PF09142.11 EPS32356.1 - 0.072 12.9 0.0 4.1 7.3 0.0 2.5 2 0 0 2 2 2 0 tRNA Pseudouridine synthase II, C terminal AAA_lid_2 PF17863.1 EPS32357.1 - 4.5e-07 29.6 0.3 1.3e-06 28.2 0.3 1.8 1 0 0 1 1 1 1 AAA lid domain Bestrophin PF01062.21 EPS32358.1 - 2.3e-54 184.8 0.0 3e-54 184.4 0.0 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel FHA PF00498.26 EPS32359.1 - 4.7e-14 52.5 0.1 9e-14 51.6 0.1 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 EPS32359.1 - 2.6e-10 39.8 4.2 4.9e-10 39.0 4.2 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 EPS32359.1 - 3.4e-07 30.5 8.3 6.3e-07 29.6 8.3 1.5 1 0 0 1 1 1 1 Ring finger domain Yop-YscD_cpl PF16697.5 EPS32359.1 - 9.6e-05 22.6 0.0 0.00021 21.6 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-RING_5 PF14634.6 EPS32359.1 - 0.00045 20.1 6.0 0.00082 19.3 6.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EPS32359.1 - 0.0096 15.8 8.8 0.017 14.9 8.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPS32359.1 - 0.027 14.3 7.4 0.055 13.3 7.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 EPS32359.1 - 0.055 13.8 4.8 0.12 12.7 4.8 1.6 1 0 0 1 1 1 0 RING-like domain zf-ANAPC11 PF12861.7 EPS32359.1 - 0.064 13.3 3.0 0.12 12.4 3.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EPS32359.1 - 0.066 13.5 8.6 0.18 12.1 8.6 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain PHD PF00628.29 EPS32359.1 - 0.15 12.0 5.6 0.31 11.0 5.6 1.5 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.6 EPS32359.1 - 1.1 9.4 7.5 2.1 8.6 6.8 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 EPS32359.1 - 2 8.1 7.9 4.5 7.0 7.9 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Arm PF00514.23 EPS32360.1 - 1.6e-72 237.6 29.2 7.7e-13 48.0 0.1 11.5 11 1 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EPS32360.1 - 5.9e-18 65.0 13.3 2e-05 25.0 0.2 8.5 7 2 2 9 9 9 5 HEAT-like repeat HEAT_2 PF13646.6 EPS32360.1 - 8.3e-16 58.2 9.8 0.0024 18.2 0.0 7.0 3 3 4 7 7 7 5 HEAT repeats HEAT PF02985.22 EPS32360.1 - 4e-15 54.6 13.8 0.34 11.3 0.0 9.4 10 0 0 10 10 10 5 HEAT repeat Arm_2 PF04826.13 EPS32360.1 - 2e-11 43.8 6.2 1.1e-07 31.6 1.8 2.6 1 1 1 2 2 2 2 Armadillo-like Adaptin_N PF01602.20 EPS32360.1 - 3e-10 39.3 8.2 9.6e-07 27.7 1.0 2.8 1 1 1 2 2 2 2 Adaptin N terminal region KAP PF05804.12 EPS32360.1 - 5.2e-10 38.2 1.0 9.2e-10 37.3 1.0 1.4 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.14 EPS32360.1 - 5.6e-08 32.4 2.0 0.00081 18.8 1.2 3.2 2 1 1 3 3 3 2 V-ATPase subunit H Cnd1 PF12717.7 EPS32360.1 - 6.6e-05 23.0 7.0 0.042 13.9 0.1 4.8 3 1 4 7 7 7 2 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 EPS32360.1 - 0.00012 22.1 7.0 0.75 9.7 0.1 4.0 1 1 2 4 4 4 3 Domain of unknown function (DUF3361) DUF5578 PF17741.1 EPS32360.1 - 0.00098 18.6 7.7 3.5 7.0 0.0 5.1 2 1 4 6 6 6 1 Family of unknown function (DUF5578) Atx10homo_assoc PF09759.9 EPS32360.1 - 0.0022 18.0 5.6 1.2 9.2 0.1 5.0 3 2 3 6 6 6 1 Spinocerebellar ataxia type 10 protein domain IFRD PF05004.13 EPS32360.1 - 0.0057 15.8 6.1 1.8 7.6 0.3 4.4 3 2 1 4 4 4 2 Interferon-related developmental regulator (IFRD) HEAT_PBS PF03130.16 EPS32360.1 - 0.012 16.2 4.9 25 5.9 0.3 6.1 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.7 EPS32360.1 - 0.021 15.4 0.1 4.1 8.1 0.1 3.6 2 1 2 4 4 3 0 Vacuolar 14 Fab1-binding region UNC45-central PF11701.8 EPS32360.1 - 0.056 13.4 1.8 6.4 6.7 0.2 3.2 2 1 1 3 3 3 0 Myosin-binding striated muscle assembly central EXOSC1 PF10447.9 EPS32361.1 - 2.4e-29 102.2 1.5 4.5e-29 101.2 1.5 1.5 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 EPS32361.1 - 3.4e-12 46.0 0.3 5.7e-12 45.2 0.3 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region GTP_EFTU PF00009.27 EPS32362.1 - 4.2e-56 189.6 0.0 7.3e-56 188.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EPS32362.1 - 1.7e-15 56.8 0.0 4.4e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EPS32362.1 - 7.6e-08 32.6 0.0 2.2e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EPS32362.1 - 1.1e-06 28.6 0.0 2.7e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 EPS32362.1 - 0.0035 17.1 0.0 0.097 12.5 0.0 3.0 2 1 0 2 2 2 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 EPS32362.1 - 0.11 12.6 0.0 0.29 11.2 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF4604 PF15377.6 EPS32363.1 - 3e-22 79.8 13.0 3.5e-22 79.7 13.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) Prp19 PF08606.11 EPS32364.1 - 5.2e-32 109.6 3.2 8.9e-32 108.9 3.2 1.4 1 0 0 1 1 1 1 Prp19/Pso4-like ANAPC4_WD40 PF12894.7 EPS32364.1 - 5.5e-18 65.0 0.3 3.4e-06 27.3 0.0 5.0 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EPS32364.1 - 1.6e-14 54.0 4.9 0.0056 17.5 0.0 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 EPS32364.1 - 2.7e-09 36.6 0.1 0.00013 21.2 0.0 2.2 1 1 1 2 2 2 2 Coatomer WD associated region WD40_like PF17005.5 EPS32364.1 - 3.9e-07 29.7 0.0 3.9e-06 26.4 0.0 2.2 1 1 1 2 2 2 1 WD40-like domain eIF2A PF08662.11 EPS32364.1 - 2.1e-05 24.5 0.2 0.0038 17.1 0.1 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A U-box PF04564.15 EPS32364.1 - 0.0049 17.0 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 U-box domain V_ATPase_I_N PF18670.1 EPS32364.1 - 0.0054 17.1 0.2 0.012 16.0 0.2 1.5 1 0 0 1 1 1 1 V-type ATPase subunit I, N-terminal domain Frtz PF11768.8 EPS32364.1 - 0.011 14.0 0.0 0.29 9.4 0.0 2.2 1 1 2 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Cytochrom_D1 PF02239.16 EPS32364.1 - 0.014 13.9 0.3 0.13 10.8 0.2 2.2 2 1 1 3 3 3 0 Cytochrome D1 heme domain IceA2 PF05862.11 EPS32364.1 - 0.063 13.2 0.9 21 5.2 0.7 2.7 2 0 0 2 2 2 0 Helicobacter pylori IceA2 protein MMS1_N PF10433.9 EPS32364.1 - 0.077 11.6 0.0 0.44 9.1 0.0 2.2 1 1 0 1 1 1 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Ge1_WD40 PF16529.5 EPS32364.1 - 0.11 11.5 0.8 0.24 10.3 0.1 2.0 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein HPS3_N PF14761.6 EPS32364.1 - 0.14 11.6 0.0 24 4.4 0.0 3.2 1 1 2 4 4 4 0 Hermansky-Pudlak syndrome 3 zf-Nse PF11789.8 EPS32364.1 - 0.17 11.7 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.6 EPS32365.1 - 0.0023 17.8 3.5 0.0039 17.1 3.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EPS32365.1 - 0.0046 16.8 1.9 0.0062 16.4 0.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPS32365.1 - 0.0052 16.8 1.4 0.01 15.8 1.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 EPS32365.1 - 0.0086 16.4 2.1 0.029 14.7 2.2 1.8 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EPS32365.1 - 0.17 11.8 3.8 0.75 9.7 4.3 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EPS32365.1 - 0.19 11.9 0.2 0.19 11.9 0.2 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING FYVE PF01363.21 EPS32365.1 - 0.19 11.9 2.2 0.46 10.7 2.1 1.7 1 1 0 1 1 1 0 FYVE zinc finger zf-C3HC4_3 PF13920.6 EPS32365.1 - 0.31 10.9 4.2 0.91 9.4 4.2 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EPS32365.1 - 1.3 9.0 3.7 0.55 10.1 0.6 1.9 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 IBR PF01485.21 EPS32365.1 - 2.8 8.2 6.2 13 6.1 2.3 2.3 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain L51_S25_CI-B8 PF05047.16 EPS32366.1 - 1.9e-17 62.9 0.2 3.6e-17 62.0 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain U1snRNP70_N PF12220.8 EPS32367.1 - 1.9e-26 92.5 2.4 3.6e-26 91.6 2.4 1.5 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 EPS32367.1 - 3.2e-16 58.9 0.0 5.3e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EPS32367.1 - 4e-05 23.6 0.0 6.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif RL10P_insert PF17777.1 EPS32368.1 - 5.4e-22 77.6 0.0 8.6e-22 76.9 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 EPS32368.1 - 1.8e-17 63.3 0.0 4.5e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 MDM10 PF12519.8 EPS32369.1 - 7.9e-148 493.2 8.2 1.3e-126 423.3 8.7 2.0 1 1 1 2 2 2 2 Mitochondrial distribution and morphology protein 10 TIM PF00121.18 EPS32370.1 - 3.1e-91 305.1 0.4 3.5e-91 304.9 0.4 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase DeoRC PF00455.22 EPS32370.1 - 0.014 15.3 0.2 2.1 8.3 0.1 2.7 2 1 1 3 3 3 0 DeoR C terminal sensor domain Dak1_2 PF13684.6 EPS32370.1 - 0.038 13.1 0.6 0.15 11.1 0.3 1.9 1 1 1 2 2 2 0 Dihydroxyacetone kinase family Snf7 PF03357.21 EPS32372.1 - 2e-35 121.9 18.2 2e-35 121.9 18.2 1.6 1 1 1 2 2 2 1 Snf7 Ist1 PF03398.14 EPS32372.1 - 0.12 12.3 5.6 0.12 12.3 4.8 1.4 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway DSBA PF01323.20 EPS32372.1 - 1.2 8.9 6.4 5.6 6.7 6.4 1.9 1 1 0 1 1 1 0 DSBA-like thioredoxin domain YlqD PF11068.8 EPS32372.1 - 1.2 9.5 17.5 1.5 9.2 7.3 2.2 1 1 1 2 2 2 0 YlqD protein DUF4407 PF14362.6 EPS32372.1 - 2 7.7 6.9 2.8 7.2 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Syntaxin-6_N PF09177.11 EPS32372.1 - 2 9.0 6.4 4.5 7.9 4.6 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Dynamin_N PF00350.23 EPS32373.1 - 1.7e-17 64.0 0.5 4e-17 62.8 0.0 1.9 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 EPS32373.1 - 8.9e-10 38.7 0.0 4.6e-09 36.4 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EPS32373.1 - 1.1e-06 28.4 2.3 2e-05 24.2 0.2 2.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IIGP PF05049.13 EPS32373.1 - 0.027 13.6 0.0 0.057 12.5 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) DUF2205 PF10224.9 EPS32373.1 - 0.069 13.1 0.9 0.21 11.6 0.9 1.8 1 0 0 1 1 1 0 Short coiled-coil protein TsaE PF02367.17 EPS32373.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_18 PF13238.6 EPS32373.1 - 0.14 12.7 0.0 0.48 11.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain DUF883 PF05957.13 EPS32373.1 - 1.3 9.7 8.4 4 8.1 0.0 4.0 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) Glyco_hydro_43 PF04616.14 EPS32374.1 - 1.9e-60 204.6 3.0 2.4e-60 204.3 3.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 EPS32374.1 - 7.6e-16 58.4 0.0 1.1e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 Beta xylosidase C-terminal Concanavalin A-like domain PTCB-BRCT PF12738.7 EPS32375.1 - 2.9e-51 171.3 0.0 8.9e-24 83.2 0.3 3.5 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.26 EPS32375.1 - 2.4e-32 111.1 0.0 4.1e-14 52.7 0.2 4.5 4 1 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EPS32375.1 - 7.9e-13 48.6 0.0 3e-06 27.6 0.0 4.5 4 0 0 4 4 4 3 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EPS32375.1 - 3.6e-08 33.6 0.6 0.0033 17.7 0.0 3.9 4 0 0 4 4 4 2 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 EPS32375.1 - 0.021 14.9 0.1 3.1 7.9 0.0 3.8 5 0 0 5 5 5 0 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 EPS32375.1 - 0.023 14.6 0.0 1.3 8.9 0.0 2.8 3 0 0 3 3 3 0 Regulator of Ty1 transposition protein 107 BRCT domain PIF1 PF05970.14 EPS32376.1 - 4.2e-64 217.0 0.1 2.3e-48 165.2 0.0 2.1 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 EPS32376.1 - 7.2e-25 87.8 0.0 1.2e-24 87.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EPS32376.1 - 2.5e-12 47.3 0.0 5e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EPS32376.1 - 1.3e-07 31.9 0.0 4.2e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EPS32376.1 - 2.7e-05 23.8 0.0 5.7e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region Herpes_Helicase PF02689.14 EPS32376.1 - 0.00018 19.6 0.0 0.00096 17.2 0.0 2.0 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.6 EPS32376.1 - 0.00019 21.2 0.1 0.0009 19.0 0.1 2.2 2 0 0 2 2 1 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 EPS32376.1 - 0.0003 21.2 0.0 0.0008 19.8 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 EPS32376.1 - 0.00041 20.8 0.0 0.00083 19.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EPS32376.1 - 0.0023 18.3 0.0 0.0075 16.6 0.0 2.0 1 1 0 1 1 1 1 RNA helicase Viral_helicase1 PF01443.18 EPS32376.1 - 0.0036 17.1 0.0 1.3 8.7 0.0 2.7 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 EPS32376.1 - 0.0064 16.5 0.1 0.023 14.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EPS32376.1 - 0.0089 15.3 0.0 0.019 14.2 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 EPS32376.1 - 0.013 15.4 1.1 0.078 12.9 1.1 2.1 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 EPS32376.1 - 0.018 14.2 0.0 0.03 13.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DUF5605 PF18310.1 EPS32376.1 - 0.02 14.8 0.0 0.14 12.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5605) SH3_13 PF18335.1 EPS32376.1 - 0.021 14.6 0.0 0.065 13.1 0.0 1.8 1 0 0 1 1 1 0 ATP-dependent RecD-like DNA helicase SH3 domain TrwB_AAD_bind PF10412.9 EPS32376.1 - 0.031 13.2 0.1 0.064 12.2 0.1 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain NACHT PF05729.12 EPS32376.1 - 0.032 14.2 0.0 0.063 13.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 EPS32376.1 - 0.043 13.8 0.3 0.44 10.6 0.3 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) UvrD-helicase PF00580.21 EPS32376.1 - 0.053 13.0 0.0 0.053 13.0 0.0 1.6 2 0 0 2 2 1 0 UvrD/REP helicase N-terminal domain T2SSE PF00437.20 EPS32376.1 - 0.066 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.27 EPS32376.1 - 0.071 13.6 0.2 0.35 11.4 0.1 2.1 1 1 0 2 2 1 0 ABC transporter PhoH PF02562.16 EPS32376.1 - 0.085 12.3 0.0 0.55 9.7 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein ResIII PF04851.15 EPS32376.1 - 0.087 12.8 0.3 0.35 10.8 0.1 1.9 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit RsgA_GTPase PF03193.16 EPS32376.1 - 0.13 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_11 PF13086.6 EPS32376.1 - 0.2 11.4 0.0 0.2 11.4 0.0 2.6 3 1 0 3 3 3 0 AAA domain Herpes_DNAp_acc PF04929.12 EPS32376.1 - 4.5 6.1 12.6 7.3 5.5 12.6 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor YjeF_N PF03853.15 EPS32377.1 - 1.8e-42 145.1 0.2 2.6e-42 144.6 0.2 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 EPS32377.1 - 1.4e-06 29.1 0.4 3.1e-06 28.0 0.4 1.6 1 0 0 1 1 1 1 FDF domain Zn_clus PF00172.18 EPS32378.1 - 1.1e-08 35.0 7.1 1.1e-08 35.0 7.1 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPS32378.1 - 0.0018 17.3 0.2 0.0032 16.6 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pro_isomerase PF00160.21 EPS32379.1 - 1.7e-41 142.1 0.0 3.3e-41 141.2 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-NOSIP PF15906.5 EPS32379.1 - 0.0012 18.9 0.0 0.0029 17.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein U-box PF04564.15 EPS32379.1 - 0.0016 18.6 0.0 0.0086 16.2 0.0 2.1 1 1 1 2 2 2 1 U-box domain Rtf2 PF04641.12 EPS32379.1 - 0.004 16.6 0.0 0.036 13.4 0.0 2.3 1 1 0 1 1 1 1 Rtf2 RING-finger PP2C PF00481.21 EPS32380.1 - 1.7e-63 214.7 0.2 6.1e-52 176.8 0.6 2.9 1 1 1 2 2 2 2 Protein phosphatase 2C Mhr1 PF12829.7 EPS32381.1 - 1.5e-28 98.7 1.2 1.8e-28 98.5 0.2 1.7 2 0 0 2 2 2 1 Transcriptional regulation of mitochondrial recombination TnsD PF15978.5 EPS32381.1 - 0.004 16.2 1.2 0.0062 15.6 1.2 1.2 1 0 0 1 1 1 1 Tn7-like transposition protein D DUF3105 PF11303.8 EPS32381.1 - 0.034 14.3 0.1 0.08 13.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3105) Ribosomal_S6 PF01250.17 EPS32381.1 - 0.24 11.7 2.8 24 5.3 0.1 3.2 3 0 0 3 3 3 0 Ribosomal protein S6 Atg14 PF10186.9 EPS32382.1 - 2.4e-13 49.9 18.3 6.1e-12 45.3 0.1 2.2 2 0 0 2 2 2 2 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 EPS32382.1 - 3.6e-05 22.8 1.7 0.43 9.4 0.0 3.2 3 0 0 3 3 3 2 Vacuolar protein sorting 38 APG6 PF04111.12 EPS32382.1 - 0.062 13.3 0.0 0.19 11.6 0.0 1.7 2 0 0 2 2 2 0 Apg6 BARA domain DUF507 PF04368.13 EPS32382.1 - 0.07 13.1 2.0 0.12 12.3 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF507) CDH PF02611.15 EPS32382.1 - 0.1 12.2 0.7 0.17 11.5 0.7 1.4 1 0 0 1 1 1 0 CDP-diacylglycerol pyrophosphatase Cgr1 PF03879.14 EPS32382.1 - 0.68 10.3 9.8 1.2 9.5 9.8 1.3 1 0 0 1 1 1 0 Cgr1 family Nup88 PF10168.9 EPS32382.1 - 2.2 6.0 9.6 3.1 5.5 9.6 1.1 1 0 0 1 1 1 0 Nuclear pore component AAA_13 PF13166.6 EPS32382.1 - 3.1 6.3 9.4 4.3 5.9 9.4 1.1 1 0 0 1 1 1 0 AAA domain Zn_clus PF00172.18 EPS32383.1 - 5.6e-07 29.6 14.8 8.5e-07 29.0 14.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Asp PF00026.23 EPS32384.1 - 1.2e-70 238.5 8.3 1.4e-70 238.2 8.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EPS32384.1 - 4.7e-08 33.5 2.7 8.1e-05 22.9 1.3 2.9 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EPS32384.1 - 4.4e-05 24.0 2.7 0.012 16.2 0.6 3.3 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 EPS32384.1 - 0.1 12.4 0.0 0.28 10.9 0.0 1.8 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal PalH PF08733.10 EPS32385.1 - 2.8e-110 368.4 0.0 3.3e-110 368.2 0.0 1.1 1 0 0 1 1 1 1 PalH/RIM21 NAM-associated PF14303.6 EPS32385.1 - 0.14 12.9 0.4 0.31 11.8 0.4 1.5 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain MFS_1 PF07690.16 EPS32386.1 - 1.3e-43 149.4 20.3 2.1e-36 125.6 11.5 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EPS32386.1 - 1.4e-06 27.2 19.6 0.00053 18.7 7.8 3.0 2 1 0 2 2 2 2 MFS/sugar transport protein OATP PF03137.20 EPS32386.1 - 0.00079 17.8 0.7 0.00079 17.8 0.7 2.0 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 EPS32386.1 - 0.0025 16.7 10.5 0.91 8.3 6.7 2.9 2 1 1 3 3 3 2 MFS_1 like family F-box-like PF12937.7 EPS32387.1 - 1e-07 31.7 0.2 2e-07 30.8 0.2 1.5 1 0 0 1 1 1 1 F-box-like PhyH PF05721.13 EPS32388.1 - 9.3e-11 42.4 0.0 1.5e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 EPS32388.1 - 1.8e-08 33.6 0.1 0.00012 21.0 0.0 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF1479) Binary_toxB PF03495.14 EPS32388.1 - 0.11 12.7 0.1 0.25 11.5 0.1 1.6 1 0 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA Ca-binding domain DIOX_N PF14226.6 EPS32389.1 - 1.6e-35 122.4 0.0 2.5e-35 121.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EPS32389.1 - 5e-18 65.5 0.0 8.5e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPT PF03151.16 EPS32390.1 - 2.6e-26 92.6 23.1 3.2e-26 92.4 23.1 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 EPS32390.1 - 2.1e-05 23.9 22.3 3.9e-05 23.0 22.3 1.4 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 EPS32390.1 - 0.061 13.5 38.0 0.065 13.4 8.7 2.7 3 0 0 3 3 3 0 EamA-like transporter family DUF883 PF05957.13 EPS32390.1 - 0.12 13.0 0.1 0.24 12.0 0.1 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Dabb PF07876.12 EPS32391.1 - 1.6e-22 79.9 0.0 1.9e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain MscL PF01741.18 EPS32392.1 - 1e-16 61.4 0.1 1.3e-16 61.0 0.1 1.2 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL C1_1 PF00130.22 EPS32392.1 - 0.014 15.3 1.4 0.021 14.7 1.4 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HypA PF01155.19 EPS32392.1 - 0.13 12.3 0.0 0.49 10.4 0.0 1.9 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA PLAC8 PF04749.17 EPS32394.1 - 3.8e-20 72.7 18.3 5.3e-20 72.3 18.3 1.2 1 0 0 1 1 1 1 PLAC8 family IPK PF03770.16 EPS32396.1 - 1e-56 191.9 0.0 1.8e-56 191.1 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase Pam17 PF08566.10 EPS32396.1 - 0.041 13.7 0.1 0.084 12.7 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 MFS_1 PF07690.16 EPS32397.1 - 1.6e-22 79.9 9.3 3.4e-22 78.8 9.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.13 EPS32397.1 - 3e-07 30.2 5.1 3e-07 30.2 5.1 2.1 2 0 0 2 2 2 1 Nodulin-like Focadhesin PF11229.8 EPS32397.1 - 0.06 11.6 0.0 0.089 11.0 0.0 1.1 1 0 0 1 1 1 0 Focadhesin EMP70 PF02990.16 EPS32397.1 - 0.43 9.2 0.0 0.43 9.2 0.0 2.2 3 1 1 4 4 4 0 Endomembrane protein 70 ERCC4 PF02732.15 EPS32398.1 - 2.5e-32 112.2 0.0 5.2e-32 111.2 0.0 1.5 1 1 0 1 1 1 1 ERCC4 domain Spore_III_AF PF09581.10 EPS32398.1 - 0.013 15.5 1.8 0.11 12.6 1.5 2.1 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) Protocadherin PF08374.11 EPS32398.1 - 0.2 11.6 4.4 22 4.9 5.4 2.4 2 0 0 2 2 2 0 Protocadherin Glycos_transf_1 PF00534.20 EPS32399.1 - 1.9e-30 105.7 0.3 8.8e-29 100.2 0.3 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EPS32399.1 - 6.3e-18 65.4 0.0 1.3e-17 64.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 EPS32399.1 - 1.1e-13 51.8 0.3 6.5e-13 49.3 0.1 2.2 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EPS32399.1 - 9.4e-06 26.2 0.0 3e-05 24.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EPS32399.1 - 0.00019 21.7 0.0 0.00054 20.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3094 PF11293.8 EPS32399.1 - 0.035 13.8 0.3 0.071 12.8 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) Kinesin PF00225.23 EPS32400.1 - 1.9e-91 306.5 0.0 1.9e-91 306.5 0.0 2.6 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EPS32400.1 - 1.4e-19 70.5 0.0 5.7e-16 58.8 0.0 3.1 1 1 1 2 2 2 2 Microtubule binding CEP63 PF17045.5 EPS32400.1 - 3.3e-05 23.9 29.5 3.3e-05 23.9 29.5 7.0 4 1 4 8 8 8 1 Centrosomal protein of 63 kDa Arginase PF00491.21 EPS32401.1 - 5.6e-90 301.6 0.0 7.2e-90 301.3 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.7 EPS32401.1 - 0.064 13.5 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain MFS_1 PF07690.16 EPS32402.1 - 6.5e-35 120.7 42.0 5.3e-31 107.8 30.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS32402.1 - 4.7e-12 45.5 5.1 4.7e-12 45.5 5.1 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter MatE PF01554.18 EPS32403.1 - 4.4e-55 185.7 22.9 1.3e-28 99.7 3.8 2.3 2 0 0 2 2 2 2 MatE Tmemb_185A PF10269.9 EPS32403.1 - 0.15 11.7 3.2 0.094 12.4 0.5 1.9 2 0 0 2 2 2 0 Transmembrane Fragile-X-F protein CRAL_TRIO PF00650.20 EPS32404.1 - 4.8e-39 133.6 0.0 6.5e-39 133.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EPS32404.1 - 1.4e-15 57.2 0.2 2.7e-15 56.3 0.2 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EPS32404.1 - 0.0058 16.8 0.0 0.0091 16.2 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Pol_alpha_B_N PF08418.10 EPS32405.1 - 3.3e-80 269.6 0.0 4.5e-80 269.2 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 EPS32405.1 - 1.2e-35 122.8 0.0 1.7e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Apc13p PF05839.11 EPS32406.1 - 1.2e-20 73.5 0.0 5.9e-15 55.2 0.0 2.1 2 0 0 2 2 2 2 Apc13p protein IF-2B PF01008.17 EPS32407.1 - 9.4e-75 251.4 0.4 1.2e-74 251.1 0.4 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF3043 PF11241.8 EPS32407.1 - 3.6 7.6 6.0 6.7 6.7 6.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Kinesin PF00225.23 EPS32408.1 - 5.5e-113 377.3 0.0 9e-113 376.6 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EPS32408.1 - 2.4e-26 92.5 0.1 7.7e-26 90.8 0.0 1.8 2 0 0 2 2 2 1 Microtubule binding Spc7 PF08317.11 EPS32408.1 - 0.054 12.4 10.5 0.084 11.7 10.5 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein PRAI PF00697.22 EPS32408.1 - 0.12 12.1 0.9 0.28 10.9 0.9 1.5 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase DUF155 PF02582.14 EPS32408.1 - 0.13 12.4 1.6 0.31 11.1 1.6 1.6 1 0 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 DUF5094 PF17015.5 EPS32408.1 - 0.27 11.3 7.2 0.64 10.1 7.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5094) SIKE PF05769.11 EPS32408.1 - 0.44 10.5 14.8 1.4 8.8 14.8 1.9 1 1 0 1 1 1 0 SIKE family DUF87 PF01935.17 EPS32408.1 - 0.47 10.5 4.7 0.86 9.7 0.1 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain V_ATPase_I PF01496.19 EPS32408.1 - 1.6 6.6 10.1 2.4 6.0 10.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_23 PF13476.6 EPS32408.1 - 4 7.9 7.0 19 5.7 4.6 2.4 2 0 0 2 2 2 0 AAA domain TBCC_N PF16752.5 EPS32408.1 - 4.9 7.6 11.2 14 6.1 11.2 1.8 1 1 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain ZapB PF06005.12 EPS32408.1 - 5.9 7.4 15.7 3.2e+02 1.8 15.7 2.9 1 1 0 1 1 1 0 Cell division protein ZapB Macro_2 PF14519.6 EPS32410.1 - 0.0091 15.4 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Macro-like domain Macro PF01661.21 EPS32410.1 - 0.06 13.4 0.0 0.12 12.4 0.0 1.6 1 1 0 1 1 1 0 Macro domain Ion_trans_2 PF07885.16 EPS32411.1 - 1.5e-28 98.6 30.2 1.4e-16 60.2 7.6 3.7 4 0 0 4 4 4 2 Ion channel DUF5504 PF17608.2 EPS32411.1 - 0.022 14.8 5.8 0.065 13.3 2.5 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5504) Ion_trans PF00520.31 EPS32411.1 - 0.045 13.0 21.5 0.12 11.6 2.3 3.4 3 0 0 3 3 3 0 Ion transport protein AMP-binding PF00501.28 EPS32413.1 - 8.6e-79 265.1 0.0 1.8e-78 264.1 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EPS32413.1 - 2.8e-62 210.2 0.0 5.5e-62 209.2 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.25 EPS32413.1 - 1.1e-51 175.1 1.8 2.1e-51 174.2 1.8 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS32413.1 - 7.3e-38 130.4 1.5 1.2e-37 129.8 0.6 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPS32413.1 - 2.2e-18 66.8 1.2 4e-14 52.9 1.2 2.4 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 EPS32413.1 - 2.6e-15 56.5 0.0 1.5e-08 34.4 0.0 2.7 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EPS32413.1 - 9.6e-13 48.3 0.0 2.3e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 EPS32413.1 - 2e-09 36.9 0.1 0.00015 20.9 0.0 3.2 3 0 0 3 3 3 3 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EPS32413.1 - 6.2e-07 28.8 0.6 6.3e-05 22.2 0.0 3.0 2 1 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 EPS32413.1 - 0.00016 21.6 0.1 0.011 15.7 0.1 2.8 2 0 0 2 2 2 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EPS32413.1 - 0.00092 18.4 1.4 1.6 7.8 0.2 3.2 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.19 EPS32413.1 - 0.052 12.9 0.2 0.15 11.4 0.1 1.7 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GDP_Man_Dehyd PF16363.5 EPS32413.1 - 0.26 10.7 0.0 9.1 5.6 0.0 2.4 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Fungal_trans_2 PF11951.8 EPS32418.1 - 1.1e-50 172.5 0.0 3.1e-50 171.1 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS32418.1 - 2.3e-05 24.4 5.8 4.8e-05 23.4 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1179 PF06678.11 EPS32418.1 - 0.46 10.5 5.3 2.7 8.0 3.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) Mannosyl_trans3 PF11051.8 EPS32421.1 - 2.7e-59 200.8 0.0 9.3e-37 126.9 0.0 2.1 1 1 1 2 2 2 2 Mannosyltransferase putative BCIP PF13862.6 EPS32424.1 - 8.7e-74 247.7 0.1 1.1e-73 247.4 0.1 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein WD40 PF00400.32 EPS32426.1 - 2.2e-28 97.9 14.4 3.3e-06 27.7 0.7 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.8 EPS32426.1 - 6.2e-10 38.3 2.0 0.01 14.5 0.2 4.8 3 1 2 5 5 5 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EPS32426.1 - 1.6e-06 28.3 0.3 0.16 12.3 0.0 4.6 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain DUF5046 PF16465.5 EPS32426.1 - 0.0079 15.7 0.8 0.15 11.4 0.1 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF5046) PQQ_2 PF13360.6 EPS32426.1 - 0.018 14.6 0.3 0.093 12.3 0.1 2.1 1 1 1 2 2 2 0 PQQ-like domain APG6_N PF17675.1 EPS32426.1 - 0.76 10.3 9.8 2.8 8.5 9.7 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF724 PF05266.14 EPS32426.1 - 1.5 8.6 5.8 2.7 7.8 5.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Seryl_tRNA_N PF02403.22 EPS32426.1 - 5.7 7.2 9.1 3.3 8.0 7.0 1.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Sad1_UNC PF07738.13 EPS32427.1 - 1.4e-13 51.0 0.0 1.3e-07 31.7 0.0 2.3 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal SRR1 PF07985.12 EPS32428.1 - 2.1e-11 43.7 0.0 5.9e-11 42.2 0.0 1.8 2 0 0 2 2 2 1 SRR1 PCP_red PF08369.10 EPS32428.1 - 0.083 13.1 0.0 0.59 10.4 0.0 2.3 3 0 0 3 3 3 0 Proto-chlorophyllide reductase 57 kD subunit CBS PF00571.28 EPS32429.1 - 3.2e-23 81.9 4.7 2.8e-09 37.3 0.1 4.3 4 0 0 4 4 4 4 CBS domain DUF3677 PF12432.8 EPS32429.1 - 0.041 14.2 0.0 0.14 12.5 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3677) HTH_9 PF08221.11 EPS32429.1 - 0.15 12.2 0.9 6.5 6.9 0.0 3.5 4 0 0 4 4 4 0 RNA polymerase III subunit RPC82 helix-turn-helix domain bZIP_1 PF00170.21 EPS32432.1 - 2.9e-11 43.3 11.7 6.2e-11 42.2 11.7 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EPS32432.1 - 1.1e-06 28.6 11.1 1.1e-06 28.6 11.1 2.3 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 EPS32432.1 - 0.0016 18.9 8.0 0.0016 18.9 8.0 2.2 2 0 0 2 2 2 1 bZIP Maf transcription factor Nnf1 PF03980.14 EPS32432.1 - 0.036 14.4 4.2 0.07 13.5 4.2 1.5 1 0 0 1 1 1 0 Nnf1 FapA PF03961.13 EPS32432.1 - 0.076 11.6 0.9 0.098 11.2 0.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF349 PF03993.12 EPS32432.1 - 0.21 11.9 6.5 0.47 10.8 6.5 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) Sulfatase PF00884.23 EPS32433.1 - 4.2e-73 246.4 0.0 5.4e-73 246.1 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF4994 PF16385.5 EPS32433.1 - 0.04 13.8 0.0 0.091 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function An_peroxidase PF03098.15 EPS32433.1 - 0.075 11.6 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Animal haem peroxidase DUF4976 PF16347.5 EPS32433.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4976) DUF229 PF02995.17 EPS32433.1 - 0.19 10.3 0.0 0.28 9.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) ECH_2 PF16113.5 EPS32434.1 - 1.8e-129 432.0 0.0 2.3e-129 431.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EPS32434.1 - 2.3e-25 89.3 0.0 6.5e-25 87.9 0.0 1.7 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase Tube PF17212.3 EPS32434.1 - 0.043 13.9 0.0 0.07 13.2 0.0 1.3 1 0 0 1 1 1 0 Tail tubular protein Ribosomal_L4 PF00573.22 EPS32435.1 - 3.5e-45 154.1 0.0 4.3e-45 153.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family PBP PF01161.20 EPS32436.1 - 1.1e-08 35.5 0.0 1.9e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Glyco_transf_28 PF03033.20 EPS32436.1 - 0.15 12.1 0.0 0.29 11.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain Peptidase_S24 PF00717.23 EPS32437.1 - 1.1e-05 25.3 0.0 2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 EPS32437.1 - 0.00095 19.0 0.0 0.11 12.2 0.0 2.3 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 DUF1264 PF06884.11 EPS32438.1 - 1.4e-78 262.4 0.0 1.7e-78 262.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) NAD_kinase PF01513.21 EPS32442.1 - 1.1e-70 238.2 0.0 1.8e-70 237.4 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase TRAPP PF04051.16 EPS32444.1 - 1.3e-40 138.4 0.0 1.8e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF3446 PF11928.8 EPS32444.1 - 0.3 11.4 9.2 3 8.2 1.3 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain MFAP1 PF06991.11 EPS32445.1 - 5.8e-66 222.4 27.0 5.8e-66 222.4 27.0 3.3 3 1 0 3 3 3 1 Microfibril-associated/Pre-mRNA processing Rep_fac-A_3 PF08661.11 EPS32446.1 - 1.5e-27 96.0 0.0 1.8e-27 95.8 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 Ten1 PF12658.7 EPS32446.1 - 0.1 12.6 0.0 0.93 9.5 0.0 2.1 1 1 0 1 1 1 0 Telomere capping, CST complex subunit GATA PF00320.27 EPS32447.1 - 0.0003 20.3 7.2 0.0082 15.7 2.1 2.5 2 0 0 2 2 2 2 GATA zinc finger Spore_coat_CotO PF14153.6 EPS32447.1 - 9.8 6.1 9.5 28 4.5 9.5 1.8 1 0 0 1 1 1 0 Spore coat protein CotO LSM PF01423.22 EPS32448.1 - 5.9e-19 67.5 0.2 8.1e-19 67.1 0.2 1.2 1 0 0 1 1 1 1 LSM domain CAV_VP3 PF04771.12 EPS32448.1 - 0.15 12.2 0.0 0.34 11.1 0.0 1.5 1 1 1 2 2 2 0 Chicken anaemia virus VP-3 protein Dak1 PF02733.17 EPS32449.1 - 1.7e-104 349.0 0.0 2.6e-104 348.4 0.0 1.3 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 EPS32449.1 - 4e-46 157.1 0.1 6e-46 156.5 0.1 1.3 1 0 0 1 1 1 1 DAK2 domain Cullin PF00888.22 EPS32450.1 - 5e-178 593.6 0.3 6.4e-178 593.2 0.3 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EPS32450.1 - 4.8e-24 84.2 1.7 1.6e-23 82.5 1.7 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain Penicillinase_R PF03965.16 EPS32450.1 - 0.93 9.9 4.2 5 7.5 0.4 3.5 3 0 0 3 3 3 0 Penicillinase repressor Nup192 PF11894.8 EPS32451.1 - 0 1441.8 21.0 0 1441.6 21.0 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 DCB PF16213.5 EPS32451.1 - 0.017 14.8 1.6 0.45 10.2 1.6 2.7 1 1 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 GyrB_insert PF18053.1 EPS32451.1 - 0.038 13.9 0.6 0.52 10.2 0.3 2.6 2 0 0 2 2 2 0 DNA gyrase B subunit insert domain PI3_PI4_kinase PF00454.27 EPS32452.1 - 6.4e-51 173.6 0.3 2e-50 171.9 0.0 2.0 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 EPS32452.1 - 1.1e-47 161.9 3.7 2.8e-47 160.6 1.8 2.8 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 EPS32452.1 - 5.5e-12 45.3 0.1 1.4e-11 44.0 0.1 1.7 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 EPS32452.1 - 2.3e-05 23.8 7.3 4.8e-05 22.7 7.3 1.5 1 0 0 1 1 1 1 FAT domain GIT1_C PF12205.8 EPS32452.1 - 0.2 11.8 1.7 2 8.5 0.1 3.5 3 0 0 3 3 3 0 G protein-coupled receptor kinase-interacting protein 1 C term UPF0052 PF01933.18 EPS32453.1 - 2.3e-61 207.6 0.0 2.8e-61 207.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 zf-C3HC4_2 PF13923.6 EPS32454.1 - 8.8e-11 41.5 8.0 2.9e-10 39.8 3.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPS32454.1 - 4e-10 39.4 7.4 6.6e-10 38.7 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPS32454.1 - 9.4e-10 38.4 3.5 2.3e-09 37.1 1.1 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EPS32454.1 - 3.7e-09 36.6 5.6 2.4e-08 34.0 6.1 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EPS32454.1 - 3.8e-09 36.3 8.3 8.8e-09 35.1 8.3 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EPS32454.1 - 1.9e-08 34.5 9.0 4.2e-08 33.4 9.0 1.6 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EPS32454.1 - 4.1e-08 33.1 7.7 6.7e-08 32.4 7.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EPS32454.1 - 2.1e-05 24.3 11.5 0.00049 19.9 11.6 2.6 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Rad50_zn_hook PF04423.14 EPS32454.1 - 8.6e-05 22.3 0.3 0.016 15.0 0.1 2.5 2 0 0 2 2 2 1 Rad50 zinc hook motif FANCL_C PF11793.8 EPS32454.1 - 0.00033 20.8 6.0 0.0016 18.5 6.1 1.9 1 1 1 2 2 2 1 FANCL C-terminal domain zf-Nse PF11789.8 EPS32454.1 - 0.00074 19.3 2.8 0.0014 18.4 2.8 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 EPS32454.1 - 0.006 16.6 5.0 0.019 15.0 5.0 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EPS32454.1 - 0.0072 16.6 7.7 0.018 15.4 7.7 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain Zn_Tnp_IS91 PF14319.6 EPS32454.1 - 0.014 15.4 4.7 0.25 11.4 3.8 2.2 1 1 1 2 2 2 0 Transposase zinc-binding domain zf-RING_4 PF14570.6 EPS32454.1 - 0.016 15.0 6.0 0.055 13.3 6.0 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 EPS32454.1 - 0.044 13.7 1.0 0.044 13.7 1.0 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Tmpp129 PF10272.9 EPS32454.1 - 0.094 12.0 3.1 0.15 11.4 3.1 1.3 1 1 0 1 1 1 0 Putative transmembrane protein precursor zf-WRNIP1_ubi PF18279.1 EPS32454.1 - 0.095 13.4 0.6 13 6.7 0.1 2.7 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain DUF1644 PF07800.12 EPS32454.1 - 0.12 12.5 4.9 2.5 8.2 4.9 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) zf-Di19 PF05605.12 EPS32454.1 - 0.23 11.8 8.6 1.7 9.0 3.3 2.2 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 EPS32454.1 - 0.36 11.3 7.1 0.54 10.8 0.3 2.6 3 0 0 3 3 2 0 Zinc-finger double domain zf-RING_11 PF17123.5 EPS32454.1 - 0.48 10.2 10.4 0.19 11.5 6.2 2.3 2 0 0 2 2 2 0 RING-like zinc finger FYVE PF01363.21 EPS32454.1 - 0.83 9.8 6.7 2.1 8.5 6.6 1.8 1 1 0 1 1 1 0 FYVE zinc finger Elf1 PF05129.13 EPS32454.1 - 1 9.5 5.5 11 6.1 5.5 2.3 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like zinc-ribbons_6 PF07191.12 EPS32454.1 - 1.2 9.2 7.7 1.4 8.9 3.1 2.1 1 1 1 2 2 2 0 zinc-ribbons zf-MIZ PF02891.20 EPS32454.1 - 9.2 6.1 10.1 72 3.3 0.4 2.3 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger DNApol_Exo PF18136.1 EPS32455.1 - 2.1e-106 355.2 0.0 3.8e-106 354.4 0.0 1.4 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 EPS32455.1 - 2.8e-54 184.6 0.0 5.4e-54 183.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family A DUF1841 PF08897.11 EPS32455.1 - 0.1 12.6 0.2 0.28 11.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1841) Sugar_tr PF00083.24 EPS32456.1 - 2.1e-80 270.8 23.7 2.5e-80 270.6 23.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS32456.1 - 2e-15 56.6 29.0 2e-15 56.6 29.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EPS32456.1 - 5.5 5.7 22.1 0.096 11.5 7.2 2.8 3 0 0 3 3 3 0 MFS_1 like family GFO_IDH_MocA PF01408.22 EPS32458.1 - 4.6e-17 62.9 0.0 8.6e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EPS32458.1 - 1.8e-16 60.1 0.1 4.2e-16 59.0 0.1 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain CorA PF01544.18 EPS32459.1 - 8.9e-26 90.9 6.1 1.2e-17 64.2 1.1 3.2 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein DUF1003 PF06210.11 EPS32459.1 - 0.13 12.4 0.1 0.3 11.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) SQS_PSY PF00494.19 EPS32460.1 - 9.3e-54 182.7 0.0 1.3e-53 182.2 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase SNF2_N PF00176.23 EPS32461.1 - 1.1e-70 238.2 0.0 1.5e-70 237.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 EPS32461.1 - 2.2e-22 78.8 0.0 4.2e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 EPS32461.1 - 3.2e-13 50.0 0.0 7.7e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPS32461.1 - 3.5e-05 23.9 0.0 9.4e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.6 EPS32461.1 - 0.0011 18.8 9.2 0.0019 18.0 9.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EPS32461.1 - 0.0028 17.4 7.9 0.0077 16.1 7.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EPS32461.1 - 0.0038 17.1 11.8 0.0073 16.2 11.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EPS32461.1 - 0.0052 16.6 13.1 0.01 15.7 13.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPS32461.1 - 0.006 16.6 11.2 0.012 15.6 11.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 EPS32461.1 - 0.015 15.6 12.2 0.036 14.4 12.2 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.6 EPS32461.1 - 0.91 9.7 11.5 1.9 8.7 11.5 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RR_TM4-6 PF06459.12 EPS32462.1 - 4.5 7.0 10.4 8.1 6.2 10.4 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GTP_EFTU PF00009.27 EPS32463.1 - 5e-19 68.6 0.0 3.9e-18 65.7 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EPS32463.1 - 1.7e-07 31.5 1.7 6.2e-07 29.7 1.7 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 EPS32463.1 - 2.8e-05 24.4 0.0 6.6e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain PduV-EutP PF10662.9 EPS32463.1 - 0.0087 15.8 0.4 0.72 9.6 0.1 3.1 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 EPS32463.1 - 0.043 13.9 0.1 0.13 12.4 0.1 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase LSM PF01423.22 EPS32464.1 - 7e-19 67.3 0.3 8.8e-19 67.0 0.3 1.2 1 0 0 1 1 1 1 LSM domain ATP13 PF12921.7 EPS32465.1 - 1.5e-25 89.2 0.1 3.8e-25 88.0 0.1 1.7 1 0 0 1 1 1 1 Mitochondrial ATPase expression PPR_3 PF13812.6 EPS32465.1 - 1.8e-08 34.3 0.0 0.00057 19.9 0.0 2.5 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR_2 PF13041.6 EPS32465.1 - 0.00059 20.0 0.0 0.92 9.8 0.0 3.1 3 0 0 3 3 3 2 PPR repeat family PIG-L PF02585.17 EPS32466.1 - 8.7e-29 100.8 0.0 1.3e-28 100.2 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase LDB19 PF13002.7 EPS32468.1 - 1.1e-58 198.1 0.0 2.1e-58 197.3 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.29 EPS32468.1 - 6.6e-08 32.7 0.1 2e-07 31.2 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain HscB_4_cys PF18256.1 EPS32471.1 - 0.072 12.9 0.2 0.13 12.1 0.2 1.4 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif GpcrRhopsn4 PF10192.9 EPS32472.1 - 0.013 14.9 5.1 0.028 13.8 5.1 1.4 1 0 0 1 1 1 0 Rhodopsin-like GPCR transmembrane domain AMP-binding PF00501.28 EPS32474.1 - 8.9e-69 232.1 0.0 1.2e-68 231.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EPS32474.1 - 3.9e-16 59.8 0.7 6.8e-16 59.0 0.1 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain CN_hydrolase PF00795.22 EPS32475.1 - 5.7e-38 130.7 0.0 1.3e-37 129.6 0.0 1.6 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase Gene66 PF02053.15 EPS32475.1 - 0.17 11.5 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Gene 66 (IR5) protein Ferritin_2 PF13668.6 EPS32477.1 - 5.1e-16 59.1 0.1 7.5e-16 58.6 0.1 1.2 1 0 0 1 1 1 1 Ferritin-like domain DUF3658 PF12395.8 EPS32477.1 - 0.0082 16.0 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function adh_short PF00106.25 EPS32478.1 - 5.3e-36 123.9 0.4 1.6e-35 122.3 0.4 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS32478.1 - 7.4e-35 120.6 0.5 2.1e-33 115.9 0.5 2.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPS32478.1 - 2.4e-10 40.6 1.3 1.5e-09 38.0 0.3 2.3 3 0 0 3 3 3 1 KR domain Polysacc_synt_2 PF02719.15 EPS32478.1 - 0.036 13.2 0.0 0.06 12.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EPS32478.1 - 0.093 11.7 0.0 0.22 10.5 0.0 1.6 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1776 PF08643.10 EPS32478.1 - 0.15 11.4 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DIOX_N PF14226.6 EPS32479.1 - 5.1e-26 91.7 0.0 8.8e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EPS32479.1 - 1.2e-18 67.5 0.0 2.2e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily EthD PF07110.11 EPS32480.1 - 0.0014 19.7 0.0 0.0027 18.8 0.0 1.4 1 1 0 1 1 1 1 EthD domain NAGLU PF05089.12 EPS32480.1 - 0.0057 15.7 0.0 0.0064 15.5 0.0 1.0 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain Amidohydro_2 PF04909.14 EPS32481.1 - 2.3e-28 99.8 0.0 3e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase DltD PF04914.12 EPS32481.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 DltD protein PDE8 PF08629.10 EPS32481.1 - 0.16 12.0 0.1 0.34 10.9 0.1 1.5 1 0 0 1 1 1 0 PDE8 phosphodiesterase TatD_DNase PF01026.21 EPS32481.1 - 0.21 10.9 0.0 1.1 8.6 0.0 1.9 2 0 0 2 2 2 0 TatD related DNase Mei4 PF13971.6 EPS32482.1 - 0.00023 20.8 0.3 0.0004 20.0 0.3 1.4 1 0 0 1 1 1 1 Meiosis-specific protein Mei4 Flagellar_rod PF05149.12 EPS32482.1 - 0.045 13.2 1.6 0.077 12.5 1.6 1.2 1 0 0 1 1 1 0 Paraflagellar rod protein DnaJ PF00226.31 EPS32483.1 - 2.3e-18 66.1 0.7 4.6e-18 65.1 0.7 1.6 1 0 0 1 1 1 1 DnaJ domain Presenilin PF01080.17 EPS32483.1 - 0.0024 16.7 2.3 0.0024 16.7 2.3 1.4 2 0 0 2 2 2 1 Presenilin RRM_1 PF00076.22 EPS32483.1 - 0.043 13.6 0.0 0.21 11.5 0.0 2.2 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) REGB_T4 PF10715.9 EPS32483.1 - 0.088 13.0 0.4 0.23 11.6 0.4 1.7 1 0 0 1 1 1 0 T4-page Endoribonuclease RegB GCV_T PF01571.21 EPS32484.1 - 2.9e-06 26.8 0.0 4.8e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain Prd1-P2 PF09214.11 EPS32485.1 - 5.5e-05 22.1 0.6 0.19 10.5 0.0 2.1 2 0 0 2 2 2 2 Bacteriophage Prd1, adsorption protein P2 AFT PF08731.11 EPS32485.1 - 0.00018 21.8 2.8 0.067 13.6 0.0 3.1 2 2 0 2 2 2 2 Transcription factor AFT Endonuc-FokI_C PF09254.11 EPS32485.1 - 0.24 10.6 0.0 0.9 8.8 0.0 1.7 2 0 0 2 2 2 0 Restriction endonuclease FokI, C terminal DCP2 PF05026.13 EPS32486.1 - 3.1e-30 104.3 1.6 6.1e-30 103.4 1.6 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 EPS32486.1 - 1.9e-18 66.8 0.1 3.8e-18 65.8 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain DUF4112 PF13430.6 EPS32487.1 - 6.5e-36 122.8 0.5 8.5e-36 122.4 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) CTU2 PF10288.9 EPS32488.1 - 6.7e-08 32.8 0.4 3.1e-06 27.4 0.0 2.4 1 1 1 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 FYVE PF01363.21 EPS32488.1 - 0.034 14.3 5.9 3.6 7.8 2.3 2.4 2 0 0 2 2 2 0 FYVE zinc finger DUF1289 PF06945.13 EPS32488.1 - 0.053 13.3 3.1 0.29 11.0 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1289) zf-C3HC4_3 PF13920.6 EPS32488.1 - 0.44 10.4 7.6 0.97 9.3 2.6 3.0 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 EPS32488.1 - 1.9 8.6 5.1 26 4.9 0.5 2.8 2 1 0 2 2 2 0 Double zinc ribbon Lung_7-TM_R PF06814.13 EPS32489.1 - 3.3e-70 236.7 14.8 4e-70 236.4 14.8 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF1308 PF07000.11 EPS32490.1 - 5.7e-10 39.4 0.0 5.7e-09 36.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1308) LEDGF PF11467.8 EPS32490.1 - 0.031 13.9 0.0 0.074 12.7 0.0 1.6 1 0 0 1 1 1 0 Lens epithelium-derived growth factor (LEDGF) WD40 PF00400.32 EPS32491.1 - 6e-14 52.2 11.6 3.4e-06 27.7 0.3 6.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS32491.1 - 1.8e-07 31.3 0.0 0.011 16.0 0.0 3.8 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EPS32491.1 - 0.0015 17.2 0.8 0.43 9.1 0.2 3.5 2 2 0 3 3 3 2 Cytochrome D1 heme domain WDCP PF15390.6 EPS32491.1 - 0.034 12.5 0.3 0.083 11.3 0.2 1.5 1 1 1 2 2 2 0 WD repeat and coiled-coil-containing protein family Mito_carr PF00153.27 EPS32492.1 - 5.3e-54 180.1 3.1 4e-18 65.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PepSY_2 PF13670.6 EPS32493.1 - 0.12 12.3 0.2 0.12 12.3 0.2 2.4 2 1 0 2 2 2 0 Peptidase propeptide and YPEB domain DUF3759 PF12585.8 EPS32494.1 - 1.5e-32 111.4 1.6 1.8e-32 111.2 1.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) EF-1_beta_acid PF10587.9 EPS32494.1 - 0.59 10.6 0.1 0.59 10.6 0.1 2.5 3 0 0 3 3 3 0 Eukaryotic elongation factor 1 beta central acidic region Ran_BP1 PF00638.18 EPS32496.1 - 5.3e-50 168.8 2.0 1.2e-49 167.6 2.0 1.6 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 EPS32496.1 - 2e-06 27.7 0.4 1.4e-05 25.0 0.4 2.1 1 1 0 1 1 1 1 WH1 domain VID27_PH PF17747.1 EPS32496.1 - 0.00017 21.8 0.1 0.00026 21.2 0.1 1.3 1 0 0 1 1 1 1 VID27 PH-like domain RAI1 PF08652.11 EPS32496.1 - 0.24 11.6 3.7 0.4 10.9 2.2 2.2 2 0 0 2 2 2 0 RAI1 like PD-(D/E)XK nuclease FHIPEP PF00771.20 EPS32496.1 - 1.3 7.4 4.0 1.7 7.0 4.0 1.2 1 0 0 1 1 1 0 FHIPEP family Dicty_REP PF05086.12 EPS32496.1 - 1.7 6.5 9.3 2.2 6.2 9.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CDC27 PF09507.10 EPS32496.1 - 3.4 6.9 28.6 0.47 9.8 25.0 1.4 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Rep_3 PF01051.21 EPS32496.1 - 6.7 6.5 9.9 5.5 6.7 2.7 2.4 2 1 1 3 3 3 0 Initiator Replication protein TMEM214 PF10151.9 EPS32496.1 - 9.1 4.6 12.2 15 3.9 12.2 1.3 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator YEATS PF03366.16 EPS32497.1 - 1.8e-16 59.8 0.0 3.5e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 YEATS family BET PF17035.5 EPS32497.1 - 5.6e-06 26.4 0.2 1.1e-05 25.5 0.2 1.5 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Phosducin PF02114.16 EPS32498.1 - 5.8e-11 41.8 0.0 3.5e-08 32.7 0.0 2.5 2 1 1 3 3 3 2 Phosducin FAM176 PF14851.6 EPS32498.1 - 0.7 9.6 6.1 5.2 6.7 0.4 2.4 1 1 0 2 2 2 0 FAM176 family WD40 PF00400.32 EPS32499.1 - 1e-39 133.8 19.4 8e-06 26.5 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS32499.1 - 3.3e-16 59.4 0.0 0.0005 20.3 0.1 5.2 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EPS32499.1 - 4.4e-05 23.4 0.0 0.12 12.3 0.0 2.8 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EPS32499.1 - 0.00045 19.6 0.0 0.039 13.3 0.0 3.1 2 1 1 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 EPS32499.1 - 0.035 13.1 0.2 17 4.3 0.0 3.6 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein zf-MYND PF01753.18 EPS32501.1 - 7.7e-08 32.3 20.3 1.7e-07 31.2 20.3 1.6 1 0 0 1 1 1 1 MYND finger DIOX_N PF14226.6 EPS32502.1 - 2e-19 70.5 0.0 3.1e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EPS32502.1 - 7.5e-13 48.8 0.0 1.7e-12 47.7 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MKT1_C PF12246.8 EPS32503.1 - 1.3e-78 263.5 0.0 2e-78 262.9 0.0 1.3 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 EPS32503.1 - 1.7e-29 102.0 0.0 4.7e-29 100.6 0.0 1.8 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 EPS32503.1 - 0.00023 21.6 0.0 0.00067 20.1 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain NAP PF00956.18 EPS32503.1 - 0.015 14.5 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 Nucleosome assembly protein (NAP) Thioredoxin PF00085.20 EPS32504.1 - 5.1e-60 199.9 0.1 1.2e-29 102.3 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin ERp29 PF07749.12 EPS32504.1 - 1.3e-22 80.5 1.1 1.7e-22 80.1 0.4 1.6 2 0 0 2 2 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 EPS32504.1 - 3.6e-20 72.4 0.1 1.4e-08 35.2 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin-like domain OST3_OST6 PF04756.13 EPS32504.1 - 7.8e-15 55.0 0.0 1.3e-06 28.0 0.0 2.1 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 EPS32504.1 - 7.1e-12 45.3 0.0 5.5e-06 26.5 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 EPS32504.1 - 1.9e-07 31.3 0.0 0.23 11.8 0.0 4.2 3 2 1 4 4 4 2 Thioredoxin-like AhpC-TSA PF00578.21 EPS32504.1 - 9.4e-07 28.8 0.0 0.045 13.7 0.0 2.6 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_6 PF13848.6 EPS32504.1 - 9.9e-06 25.6 0.2 0.011 15.6 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin-like domain TraF PF13728.6 EPS32504.1 - 2.9e-05 24.0 0.0 0.023 14.5 0.0 2.3 2 0 0 2 2 2 2 F plasmid transfer operon protein Redoxin PF08534.10 EPS32504.1 - 0.00015 21.5 0.2 0.29 10.8 0.0 2.4 2 0 0 2 2 2 2 Redoxin HyaE PF07449.11 EPS32504.1 - 0.00064 19.7 0.0 0.26 11.3 0.0 2.7 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.24 EPS32504.1 - 0.001 19.2 0.1 3.3 8.0 0.0 2.9 2 1 0 2 2 2 2 Glutaredoxin Thioredoxin_9 PF14595.6 EPS32504.1 - 0.0019 18.0 0.0 0.22 11.3 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_3 PF13192.6 EPS32504.1 - 0.016 15.2 0.0 2.3 8.3 0.0 2.8 3 0 0 3 3 3 0 Thioredoxin domain DUF836 PF05768.14 EPS32504.1 - 0.13 12.7 0.0 1.8 9.1 0.0 2.3 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) Thioredoxin_4 PF13462.6 EPS32504.1 - 0.57 10.3 4.0 79 3.4 0.1 3.7 3 2 1 4 4 4 0 Thioredoxin HSBP1 PF06825.12 EPS32505.1 - 2.7e-18 65.5 0.4 3.5e-18 65.2 0.4 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.9 EPS32505.1 - 0.0021 17.9 0.7 0.031 14.1 0.6 2.1 1 1 0 1 1 1 1 Trimeric coiled-coil oligomerisation domain of matrilin Apolipoprotein PF01442.18 EPS32505.1 - 0.0024 17.8 0.4 0.003 17.5 0.4 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 EPS32505.1 - 0.0053 16.8 0.2 0.0063 16.6 0.2 1.1 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4164 PF13747.6 EPS32505.1 - 0.031 14.5 0.4 0.064 13.5 0.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) NPV_P10 PF05531.12 EPS32505.1 - 0.032 14.7 0.2 0.046 14.2 0.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein MAP65_ASE1 PF03999.12 EPS32505.1 - 0.06 12.0 0.2 0.067 11.9 0.2 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) BORCS6 PF10157.9 EPS32505.1 - 0.061 13.5 0.1 0.084 13.1 0.1 1.4 1 1 0 1 1 1 0 BLOC-1-related complex sub-unit 6 CLZ PF16526.5 EPS32505.1 - 0.067 13.6 0.4 0.089 13.2 0.4 1.4 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels UPF0184 PF03670.13 EPS32505.1 - 0.083 13.3 1.3 0.13 12.6 1.3 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) TBCC_N PF16752.5 EPS32505.1 - 0.085 13.3 1.8 0.12 12.8 1.8 1.2 1 0 0 1 1 1 0 Tubulin-specific chaperone C N-terminal domain Snapin_Pallidin PF14712.6 EPS32505.1 - 0.1 13.0 0.1 0.14 12.6 0.1 1.1 1 0 0 1 1 1 0 Snapin/Pallidin DUF2937 PF11157.8 EPS32505.1 - 0.13 11.9 0.1 0.15 11.7 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Fzo_mitofusin PF04799.13 EPS32505.1 - 0.19 11.2 0.2 0.23 11.0 0.2 1.1 1 0 0 1 1 1 0 fzo-like conserved region Ebp2 PF05890.12 EPS32506.1 - 1.4e-93 313.4 20.6 1.4e-93 313.4 20.6 2.0 1 1 1 2 2 2 1 Eukaryotic rRNA processing protein EBP2 Nop14 PF04147.12 EPS32506.1 - 4.4 5.4 51.4 0.0041 15.4 35.3 2.1 2 0 0 2 2 2 0 Nop14-like family TruB_N PF01509.18 EPS32507.1 - 1.1e-44 152.4 0.0 3.4e-44 150.8 0.0 1.7 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 EPS32507.1 - 2.9e-06 27.3 0.0 5.8e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain Neur_chan_memb PF02932.16 EPS32507.1 - 0.75 9.8 1.8 1.3 9.0 1.8 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region OHCU_decarbox PF09349.10 EPS32510.1 - 9.7e-49 165.8 0.1 1.1e-48 165.6 0.1 1.0 1 0 0 1 1 1 1 OHCU decarboxylase BMF PF15185.6 EPS32510.1 - 0.012 15.4 0.1 0.016 14.9 0.1 1.2 1 0 0 1 1 1 0 Bcl-2-modifying factor, apoptosis WD40 PF00400.32 EPS32511.1 - 1.4e-24 85.9 13.3 3.8e-06 27.5 0.0 7.8 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS32511.1 - 1.9e-08 34.5 0.1 0.21 11.9 0.0 5.0 4 1 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EPS32511.1 - 0.0049 15.9 0.2 0.24 10.3 0.0 2.9 3 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nudix_N_2 PF14803.6 EPS32511.1 - 0.013 15.4 1.3 0.042 13.8 1.3 1.8 1 0 0 1 1 1 0 Nudix N-terminal BBS2_Mid PF14783.6 EPS32511.1 - 0.063 13.3 0.0 40 4.3 0.0 3.5 4 1 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region SRP9-21 PF05486.12 EPS32512.1 - 7.1e-30 103.3 6.7 2.1e-29 101.8 6.7 1.7 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Ribonuc_red_sm PF00268.21 EPS32513.1 - 7.9e-123 409.3 0.7 9.7e-123 409.1 0.7 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain RE_XcyI PF09571.10 EPS32513.1 - 0.034 13.4 0.0 5.8 6.1 0.0 2.1 2 0 0 2 2 2 0 XcyI restriction endonuclease Cutinase PF01083.22 EPS32515.1 - 5.6e-47 160.0 0.2 6.4e-47 159.8 0.2 1.0 1 0 0 1 1 1 1 Cutinase VirJ PF06057.11 EPS32515.1 - 0.00011 22.2 0.0 0.00017 21.5 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) PE-PPE PF08237.11 EPS32515.1 - 0.0012 18.4 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain DUF2974 PF11187.8 EPS32515.1 - 0.24 10.9 0.0 0.31 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PD40 PF07676.12 EPS32516.1 - 0.0084 16.0 0.6 0.024 14.6 0.2 2.0 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Ncstrn_small PF18266.1 EPS32516.1 - 0.16 12.0 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 Nicastrin small lobe 2OG-FeII_Oxy PF03171.20 EPS32517.1 - 3.1e-05 24.4 0.0 7.5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_transf_15 PF01793.16 EPS32518.1 - 7.2e-95 318.0 11.5 5.7e-94 315.0 11.5 1.9 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase NUDIX PF00293.28 EPS32519.1 - 1.5e-11 44.4 0.2 2.8e-11 43.6 0.2 1.4 1 1 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 EPS32519.1 - 0.019 14.9 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 NUDIX domain PH PF00169.29 EPS32520.1 - 3.6e-31 107.8 0.1 3.3e-14 53.3 0.0 2.2 2 0 0 2 2 2 2 PH domain PH_11 PF15413.6 EPS32520.1 - 1.4e-11 44.7 0.5 0.0007 20.0 0.2 3.3 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.6 EPS32520.1 - 1.8e-09 38.0 0.2 0.00011 22.6 0.0 3.4 2 2 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.6 EPS32520.1 - 8.3e-05 22.6 0.1 0.32 11.1 0.0 2.3 2 0 0 2 2 2 2 PH domain PH_2 PF08458.10 EPS32520.1 - 0.057 13.8 0.0 0.42 11.0 0.0 2.1 2 1 0 2 2 2 0 Plant pleckstrin homology-like region Mcp5_PH PF12814.7 EPS32520.1 - 0.083 13.0 0.1 0.56 10.3 0.0 2.0 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology EamA PF00892.20 EPS32521.1 - 8.3e-11 42.2 34.4 7.1e-08 32.7 2.9 3.1 3 0 0 3 3 3 2 EamA-like transporter family DUF3955 PF13127.6 EPS32521.1 - 4.6e-09 35.9 0.7 4.6e-09 35.9 0.7 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3955) PUNUT PF16913.5 EPS32521.1 - 0.0014 18.0 2.9 0.0014 18.0 2.9 2.4 2 1 0 2 2 2 1 Purine nucleobase transmembrane transport UAA PF08449.11 EPS32521.1 - 0.02 14.1 15.4 0.0058 15.9 12.6 1.5 2 0 0 2 2 2 0 UAA transporter family SLC35F PF06027.12 EPS32521.1 - 0.032 13.8 16.0 0.026 14.1 12.4 2.4 2 1 0 2 2 2 0 Solute carrier family 35 TPT PF03151.16 EPS32521.1 - 0.23 10.8 13.0 0.13 11.5 0.3 2.5 3 0 0 3 3 3 0 Triose-phosphate Transporter family Ras PF00071.22 EPS32522.1 - 1.5e-56 190.5 0.1 1.8e-56 190.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EPS32522.1 - 2.2e-32 111.8 0.0 3.1e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPS32522.1 - 1.3e-12 47.5 0.0 1.6e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EPS32522.1 - 5.5e-07 29.7 0.0 9.7e-07 28.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EPS32522.1 - 7.9e-06 25.5 0.0 0.00025 20.6 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EPS32522.1 - 1.4e-05 24.6 0.0 1.7e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EPS32522.1 - 0.00022 21.2 0.3 0.0045 16.9 0.1 2.4 1 1 2 3 3 3 1 RsgA GTPase ATP_bind_1 PF03029.17 EPS32522.1 - 0.0017 18.2 0.3 0.041 13.7 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein cobW PF02492.19 EPS32522.1 - 0.0022 17.6 0.0 0.011 15.3 0.0 1.9 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 EPS32522.1 - 0.0039 17.0 0.1 0.17 11.6 0.1 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 EPS32522.1 - 0.0043 17.4 0.0 0.0093 16.4 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain Septin PF00735.18 EPS32522.1 - 0.0056 16.0 0.1 0.086 12.1 0.0 2.2 2 0 0 2 2 2 1 Septin AAA_5 PF07728.14 EPS32522.1 - 0.015 15.3 0.0 0.033 14.2 0.0 1.7 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EPS32522.1 - 0.015 15.5 0.0 0.03 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EPS32522.1 - 0.019 14.7 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 EPS32522.1 - 0.028 13.9 0.0 0.034 13.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 EPS32522.1 - 0.039 13.5 0.1 0.065 12.7 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region NB-ARC PF00931.22 EPS32522.1 - 0.067 12.4 0.3 0.18 11.0 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.15 EPS32522.1 - 0.071 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 NTPase NACHT PF05729.12 EPS32522.1 - 0.1 12.5 0.1 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 EPS32522.1 - 0.14 12.0 1.0 0.19 11.6 0.1 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea TniB PF05621.11 EPS32522.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein ATG16 PF08614.11 EPS32523.1 - 1e-53 182.6 23.6 1.2e-53 182.4 23.6 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF4201 PF13870.6 EPS32523.1 - 1.5e-05 24.8 12.1 2.4e-05 24.1 12.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) HAUS-augmin3 PF14932.6 EPS32523.1 - 3e-05 23.7 9.0 4.5e-05 23.1 9.0 1.3 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 Golgin_A5 PF09787.9 EPS32523.1 - 4.8e-05 23.0 11.8 5.2e-05 22.9 11.8 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 MscS_porin PF12795.7 EPS32523.1 - 0.0015 18.1 11.3 0.0015 18.1 11.3 2.1 1 1 0 2 2 2 1 Mechanosensitive ion channel porin domain UPF0242 PF06785.11 EPS32523.1 - 0.0031 17.7 13.1 0.03 14.4 7.3 2.1 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus Syntaxin_2 PF14523.6 EPS32523.1 - 0.0063 16.9 6.7 0.012 15.9 6.7 1.6 1 1 0 1 1 1 1 Syntaxin-like protein GAS PF13851.6 EPS32523.1 - 0.039 13.3 16.3 0.043 13.2 14.9 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding CCDC144C PF14915.6 EPS32523.1 - 0.046 12.8 13.8 0.097 11.8 13.8 1.4 1 1 0 1 1 1 0 CCDC144C protein coiled-coil region DUF1664 PF07889.12 EPS32523.1 - 0.13 12.3 3.7 4.2 7.4 3.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) FAM76 PF16046.5 EPS32523.1 - 0.13 11.6 7.3 0.16 11.3 7.3 1.2 1 0 0 1 1 1 0 FAM76 protein DUF4407 PF14362.6 EPS32523.1 - 0.16 11.3 11.4 0.22 10.8 11.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DASH_Spc19 PF08287.11 EPS32523.1 - 0.18 11.7 16.5 4.4 7.2 16.5 2.5 1 1 0 1 1 1 0 Spc19 Spc7 PF08317.11 EPS32523.1 - 0.23 10.3 14.7 0.6 8.9 14.7 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein Noelin-1 PF12308.8 EPS32523.1 - 0.42 10.6 3.3 0.57 10.2 2.4 1.8 1 1 0 1 1 1 0 Neurogenesis glycoprotein Cluap1 PF10234.9 EPS32523.1 - 0.52 9.7 14.8 0.13 11.7 2.8 2.1 1 1 1 2 2 2 0 Clusterin-associated protein-1 BRE1 PF08647.11 EPS32523.1 - 0.6 10.2 14.0 0.62 10.2 11.9 2.1 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Med30 PF11315.8 EPS32523.1 - 0.63 10.2 7.1 3.9 7.7 7.1 2.3 1 1 0 1 1 1 0 Mediator complex subunit 30 LMBR1 PF04791.16 EPS32523.1 - 0.65 8.8 3.8 0.71 8.7 3.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein FapA PF03961.13 EPS32523.1 - 0.84 8.2 3.7 1.1 7.8 3.7 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A APG6_N PF17675.1 EPS32523.1 - 0.87 10.1 21.4 3.6 8.1 9.9 2.4 1 1 1 2 2 2 0 Apg6 coiled-coil region OmpH PF03938.14 EPS32523.1 - 1.4 9.3 11.0 7.3 6.9 11.2 2.0 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) YabA PF06156.13 EPS32523.1 - 1.4 9.6 11.5 3.9 8.2 4.5 2.3 1 1 1 2 2 2 0 Initiation control protein YabA Fez1 PF06818.15 EPS32523.1 - 1.8 8.9 16.6 2.1 8.7 15.7 1.6 1 1 0 1 1 1 0 Fez1 CENP-H PF05837.12 EPS32523.1 - 3.2 8.2 18.8 0.72 10.3 4.2 2.7 2 1 1 3 3 3 0 Centromere protein H (CENP-H) Jnk-SapK_ap_N PF09744.9 EPS32523.1 - 3.4 7.9 17.5 7.3 6.8 17.5 1.5 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Exonuc_VII_L PF02601.15 EPS32523.1 - 4 6.9 9.5 5.2 6.5 9.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DivIC PF04977.15 EPS32523.1 - 5.1 6.9 10.7 4.8 7.0 0.7 2.7 2 1 0 2 2 2 0 Septum formation initiator BST2 PF16716.5 EPS32523.1 - 7 7.3 12.1 21 5.8 0.6 2.7 1 1 1 2 2 2 0 Bone marrow stromal antigen 2 DOT1 PF08123.13 EPS32524.1 - 1.1e-77 260.2 0.3 2.5e-77 259.1 0.0 1.7 2 0 0 2 2 2 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 EPS32524.1 - 0.086 13.6 0.2 1.5 9.5 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain HNF-1_N PF04814.13 EPS32524.1 - 0.14 12.8 3.6 0.24 12.0 3.6 1.3 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Ndc1_Nup PF09531.10 EPS32524.1 - 2 7.0 5.5 2.8 6.5 5.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Spb1_C PF07780.12 EPS32525.1 - 3.1e-78 262.3 50.5 3.1e-78 262.3 50.5 4.2 2 1 1 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 EPS32525.1 - 5.8e-56 189.4 0.0 1.1e-55 188.5 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 EPS32525.1 - 3.2e-51 173.4 10.8 3.2e-51 173.4 10.8 5.1 4 1 2 6 6 6 1 Domain of unknown function (DUF3381) DUF3830 PF12903.7 EPS32525.1 - 0.14 11.9 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3830) Fungal_trans PF04082.18 EPS32527.1 - 1.2e-07 31.1 0.8 3e-07 29.7 0.6 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS32527.1 - 1.6e-07 31.4 7.3 1.6e-07 31.4 7.3 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p47_phox_C PF08944.11 EPS32527.1 - 0.17 11.3 4.5 0.27 10.7 1.0 2.7 2 0 0 2 2 2 0 NADPH oxidase subunit p47Phox, C terminal domain EF-hand_4 PF12763.7 EPS32528.1 - 7.4e-06 25.9 0.0 1.4e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Fungal_trans PF04082.18 EPS32529.1 - 6.4e-22 77.9 2.8 1.2e-21 77.0 2.8 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS32529.1 - 5.7e-06 26.3 7.8 1.4e-05 25.1 7.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 EPS32529.1 - 0.00015 22.0 2.7 0.00015 22.0 2.7 2.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPS32529.1 - 0.0032 18.2 2.1 0.0032 18.2 2.1 3.3 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2HE PF16278.5 EPS32529.1 - 0.0039 17.6 0.0 0.012 16.1 0.0 1.8 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_2 PF13465.6 EPS32529.1 - 0.0057 17.0 1.0 0.0057 17.0 1.0 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 EPS32529.1 - 0.053 13.9 0.2 0.053 13.9 0.2 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DNA_ligase_A_M PF01068.21 EPS32530.1 - 3.8e-49 167.1 0.0 3.7e-48 163.9 0.0 2.4 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EPS32530.1 - 7.1e-44 150.2 0.0 1.9e-43 148.8 0.0 1.8 2 0 0 2 2 2 1 DNA ligase N terminus BRCT_2 PF16589.5 EPS32530.1 - 1.1e-17 64.2 0.5 2.8e-13 50.1 0.1 3.4 2 1 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_A_C PF04679.15 EPS32530.1 - 1.9e-17 63.7 0.3 1.2e-16 61.1 0.0 2.5 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 EPS32530.1 - 6.7e-16 59.0 0.0 1.3e-15 58.1 0.0 1.5 1 0 0 1 1 1 1 RNA ligase LIG3_BRCT PF16759.5 EPS32530.1 - 1.3e-07 31.8 0.1 4.9e-05 23.5 0.1 2.6 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain BRCT PF00533.26 EPS32530.1 - 6.7e-07 29.6 0.0 1.9e-06 28.1 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.8 EPS32530.1 - 0.015 15.4 0.1 0.032 14.4 0.1 1.5 1 0 0 1 1 1 0 DNA ligase IV RTT107_BRCT_5 PF16770.5 EPS32530.1 - 0.039 13.8 0.0 0.78 9.7 0.0 2.4 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain Fungal_trans PF04082.18 EPS32532.1 - 1.8e-38 132.1 0.0 3.3e-38 131.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS32532.1 - 9.1e-08 32.1 7.9 1.8e-07 31.1 7.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHD PF00628.29 EPS32532.1 - 0.0042 17.0 3.8 0.0092 15.8 3.8 1.6 1 0 0 1 1 1 1 PHD-finger Metallophos PF00149.28 EPS32533.1 - 1.4e-30 107.4 0.0 3.9e-22 79.7 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EPS32533.1 - 0.19 12.2 0.2 0.51 10.8 0.2 1.7 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain COA2 PF17051.5 EPS32534.1 - 0.0021 18.1 0.1 0.0041 17.2 0.1 1.5 1 1 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 NSP2-B_epitope PF14757.6 EPS32534.1 - 0.012 15.3 0.2 0.015 15.0 0.2 1.1 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein ALG3 PF05208.13 EPS32535.1 - 2.3e-138 461.5 15.3 2.7e-138 461.3 15.3 1.0 1 0 0 1 1 1 1 ALG3 protein eIF-1a PF01176.19 EPS32536.1 - 5.1e-15 55.0 0.1 7.6e-15 54.5 0.1 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 DUF3189 PF11385.8 EPS32536.1 - 0.075 12.9 0.0 0.097 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3189) HAS-barrel PF09378.10 EPS32536.1 - 0.089 13.0 0.2 0.14 12.3 0.1 1.4 1 1 0 1 1 1 0 HAS barrel domain MFS_1 PF07690.16 EPS32537.1 - 7.7e-30 104.0 66.3 3e-25 88.9 37.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 EPS32538.1 - 4.9e-59 199.8 0.1 9.9e-59 198.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS32538.1 - 2.2e-35 122.2 0.0 3.8e-35 121.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 EPS32538.1 - 5.7e-28 96.8 19.7 9.3e-16 57.7 4.4 2.6 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.22 EPS32538.1 - 6.3e-20 70.8 30.4 4.4e-12 45.7 9.8 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 EPS32538.1 - 1.6e-14 54.4 1.2 1.8e-13 50.9 1.5 2.7 2 0 0 2 2 2 1 Protein kinase C terminal domain C2 PF00168.30 EPS32538.1 - 8.4e-06 26.0 0.1 1.6e-05 25.1 0.1 1.4 1 0 0 1 1 1 1 C2 domain FTA2 PF13095.6 EPS32538.1 - 0.018 14.7 0.1 0.19 11.4 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 EPS32538.1 - 0.037 13.3 0.0 0.069 12.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Uds1 PF15456.6 EPS32538.1 - 1.2 9.3 6.1 0.65 10.2 0.9 2.5 2 0 0 2 2 2 0 Up-regulated During Septation zf-RING_9 PF13901.6 EPS32538.1 - 5.3 7.0 22.7 3.1 7.7 8.1 2.4 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon TFCD_C PF12612.8 EPS32540.1 - 4.5e-23 82.1 0.5 4e-22 79.0 0.3 2.9 2 1 0 2 2 2 1 Tubulin folding cofactor D C terminal IFRD PF05004.13 EPS32540.1 - 2.6e-06 26.8 5.4 2.1e-05 23.8 2.0 2.7 2 0 0 2 2 2 1 Interferon-related developmental regulator (IFRD) HEAT PF02985.22 EPS32540.1 - 2.7e-05 24.0 7.6 0.07 13.4 0.0 5.9 5 0 0 5 5 5 1 HEAT repeat Vac14_Fab1_bd PF12755.7 EPS32540.1 - 0.082 13.5 0.0 1.2 9.8 0.0 3.0 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 EPS32540.1 - 0.13 12.7 11.4 1.4 9.4 0.0 5.5 8 0 0 8 8 8 0 HEAT repeats HEAT_EZ PF13513.6 EPS32540.1 - 1.2 9.7 0.0 1.2 9.7 0.0 7.8 10 0 0 10 10 10 0 HEAT-like repeat RRM_1 PF00076.22 EPS32541.1 - 1.9e-26 91.6 2.4 5.2e-12 45.4 1.1 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EPS32541.1 - 0.00023 20.8 0.0 0.0023 17.5 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ATP-synt_D PF01813.17 EPS32542.1 - 5.4e-71 238.5 1.7 6.7e-71 238.2 1.7 1.1 1 0 0 1 1 1 1 ATP synthase subunit D DUF5446 PF17522.2 EPS32542.1 - 0.71 10.1 2.4 0.87 9.8 0.7 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5446) TPR_14 PF13428.6 EPS32543.1 - 1.1e-15 56.9 11.0 5.2 8.2 0.1 11.4 9 4 3 12 12 11 2 Tetratricopeptide repeat Suf PF05843.14 EPS32543.1 - 3.3e-09 37.2 16.0 0.15 12.0 0.5 6.4 4 1 2 6 6 6 5 Suppressor of forked protein (Suf) TPR_8 PF13181.6 EPS32543.1 - 1.3e-08 34.3 6.0 0.03 14.5 0.0 7.5 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_19 PF14559.6 EPS32543.1 - 1.6e-08 34.9 1.1 0.72 10.4 0.0 5.9 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EPS32543.1 - 2.8e-07 30.7 6.2 17 5.8 0.0 7.0 6 1 0 7 7 7 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EPS32543.1 - 3.6e-07 30.2 15.6 0.45 10.5 0.0 7.4 7 2 0 7 7 7 2 Mad3/BUB1 homology region 1 TPR_15 PF13429.6 EPS32543.1 - 2.2e-05 23.8 3.7 0.0018 17.5 0.2 4.0 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EPS32543.1 - 4.9e-05 22.9 0.0 0.25 10.7 0.1 4.0 4 0 0 4 4 4 1 MalT-like TPR region TPR_2 PF07719.17 EPS32543.1 - 8.5e-05 22.4 14.6 2.4 8.5 0.0 8.0 9 0 0 9 9 8 1 Tetratricopeptide repeat SNAP PF14938.6 EPS32543.1 - 0.0004 19.9 5.7 0.045 13.2 0.9 4.5 5 1 0 5 5 5 1 Soluble NSF attachment protein, SNAP PPR_2 PF13041.6 EPS32543.1 - 0.054 13.7 0.3 21 5.4 0.0 4.1 3 0 0 3 3 3 0 PPR repeat family TPR_17 PF13431.6 EPS32543.1 - 0.054 13.9 4.3 0.88 10.1 0.0 4.9 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 EPS32543.1 - 0.14 11.8 1.0 1.9 8.2 0.0 3.2 3 0 0 3 3 3 0 TPR repeat HAT PF02184.16 EPS32543.1 - 0.15 12.0 7.9 2.8 8.0 0.0 6.4 8 0 0 8 8 6 0 HAT (Half-A-TPR) repeat NRDE-2 PF08424.10 EPS32543.1 - 0.26 10.4 13.9 0.3 10.2 0.2 5.7 3 3 0 4 4 4 0 NRDE-2, necessary for RNA interference TPR_6 PF13174.6 EPS32543.1 - 0.66 10.7 15.1 1.6 9.5 0.0 7.1 10 0 0 10 10 7 0 Tetratricopeptide repeat Sec7 PF01369.20 EPS32545.1 - 1.1e-64 217.5 0.3 1.8e-64 216.8 0.3 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 EPS32545.1 - 2.7e-20 72.9 0.1 3.3e-19 69.3 0.0 2.9 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 EPS32545.1 - 0.0046 16.6 0.3 0.016 14.9 0.3 1.9 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 RhoGEF PF00621.20 EPS32546.1 - 1e-21 78.0 0.1 1.2e-20 74.5 0.0 2.2 2 0 0 2 2 2 1 RhoGEF domain DUF3507 PF12015.8 EPS32546.1 - 3.6e-08 33.3 0.0 6.7e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) Nod1 PF17114.5 EPS32546.1 - 9.2e-05 22.6 0.0 0.00033 20.8 0.0 2.0 1 0 0 1 1 1 1 Gef2-related medial cortical node protein Nod1 Cnn_1N PF07989.11 EPS32546.1 - 0.022 14.9 2.6 0.69 10.1 0.1 2.7 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Seryl_tRNA_N PF02403.22 EPS32546.1 - 0.087 13.1 2.7 0.29 11.4 2.7 1.9 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF4922 PF16269.5 EPS32546.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4922) FAM184 PF15665.5 EPS32546.1 - 0.17 11.7 5.3 0.57 9.9 5.3 1.9 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B Exonuc_VII_L PF02601.15 EPS32546.1 - 0.99 8.9 3.6 30 4.0 6.3 2.2 2 1 0 2 2 2 0 Exonuclease VII, large subunit ATP_bind_3 PF01171.20 EPS32547.1 - 6.7e-39 133.5 0.0 1.6e-37 129.0 0.0 2.4 1 1 0 1 1 1 1 PP-loop family Asn_synthase PF00733.21 EPS32547.1 - 0.048 13.3 0.1 0.078 12.6 0.1 1.2 1 0 0 1 1 1 0 Asparagine synthase NAD_synthase PF02540.17 EPS32547.1 - 0.2 10.7 0.0 0.35 10.0 0.0 1.3 1 0 0 1 1 1 0 NAD synthase TPR_2 PF07719.17 EPS32548.1 - 2e-09 36.9 13.8 0.00065 19.6 0.0 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 EPS32548.1 - 2.3e-08 33.5 0.4 0.018 14.8 0.0 4.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EPS32548.1 - 1.4e-07 31.0 0.2 0.89 9.3 0.0 4.8 5 0 0 5 5 5 2 TPR repeat TPR_8 PF13181.6 EPS32548.1 - 0.002 18.2 4.0 0.76 10.1 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 EPS32548.1 - 0.0052 17.3 13.7 0.26 11.8 0.5 4.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 EPS32548.1 - 0.018 15.3 1.5 0.018 15.3 1.5 5.1 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 EPS32548.1 - 0.028 15.0 11.5 4.1 8.3 3.5 4.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EPS32548.1 - 0.029 15.0 18.0 2.5 8.8 0.3 6.3 6 1 1 7 7 7 0 Tetratricopeptide repeat Ofd1_CTDD PF10637.9 EPS32548.1 - 0.19 11.0 0.0 0.38 10.1 0.0 1.4 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term TPR_7 PF13176.6 EPS32548.1 - 0.28 11.3 9.2 12 6.2 0.3 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 EPS32548.1 - 8.7 7.5 14.9 11 7.1 0.5 5.3 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF3337 PF11816.8 EPS32549.1 - 2e-55 187.3 0.0 4e-55 186.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 EPS32549.1 - 5.5e-18 65.0 14.0 0.00098 19.9 0.1 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.8 EPS32549.1 - 0.017 13.8 4.6 0.041 12.5 0.2 3.0 3 1 0 4 4 4 0 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EPS32549.1 - 0.019 15.2 0.2 5.1 7.5 0.1 3.9 4 1 1 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EPS32549.1 - 0.03 13.3 0.0 0.21 10.5 0.0 2.0 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PALB2_WD40 PF16756.5 EPS32549.1 - 0.21 10.5 0.4 0.63 8.9 0.1 2.0 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Mito_carr PF00153.27 EPS32550.1 - 8.8e-40 134.6 3.0 7.9e-16 57.8 0.1 3.8 3 2 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.25 EPS32551.1 - 1.6e-45 155.5 0.0 9e-45 153.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS32551.1 - 3.5e-20 72.4 0.0 5.8e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EPS32551.1 - 0.0033 17.4 0.2 0.076 12.9 0.0 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EPS32551.1 - 0.31 9.9 0.0 0.31 9.9 0.0 1.7 2 0 0 2 2 2 0 Haspin like kinase domain SAB PF04382.13 EPS32551.1 - 0.57 10.3 3.4 0.45 10.6 1.2 2.0 2 0 0 2 2 2 0 SAB domain Ribosomal_L11 PF00298.19 EPS32552.1 - 1.2e-27 96.2 0.1 2.3e-27 95.3 0.1 1.4 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 EPS32552.1 - 3.9e-26 90.7 0.1 6.9e-26 89.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Svf1_C PF17187.4 EPS32553.1 - 1.6e-60 203.7 0.9 2.8e-60 202.9 0.1 1.8 2 1 0 2 2 2 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 EPS32553.1 - 1.9e-55 187.4 0.2 2.7e-55 186.9 0.2 1.3 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain AAA_6 PF12774.7 EPS32554.1 - 9.2e-127 422.5 0.0 5.2e-126 420.1 0.0 2.4 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 EPS32554.1 - 2.5e-124 416.0 3.8 2.5e-124 416.0 3.8 5.4 7 0 0 7 7 6 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 EPS32554.1 - 1.3e-114 383.4 5.7 1.3e-114 383.4 5.7 5.1 4 2 1 5 5 4 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 EPS32554.1 - 4.6e-75 251.5 1.2 4.6e-75 251.5 1.2 3.9 3 0 0 3 3 2 1 ATP-binding dynein motor region AAA_8 PF12780.7 EPS32554.1 - 2.5e-66 223.6 0.1 1.4e-65 221.2 0.0 2.5 3 0 0 3 3 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 EPS32554.1 - 5.8e-42 143.2 0.0 4.5e-36 124.1 0.0 4.8 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 EPS32554.1 - 7.3e-41 140.3 7.9 7.3e-41 140.3 7.9 1.9 2 0 0 2 2 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 EPS32554.1 - 2.6e-33 114.9 1.1 1.6e-10 41.1 0.0 7.0 6 1 0 6 6 5 4 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 EPS32554.1 - 4e-32 110.8 0.1 6.4e-26 90.8 0.0 4.9 4 0 0 4 4 4 2 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 EPS32554.1 - 7.3e-30 103.9 0.0 2.5e-28 99.0 0.0 2.6 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_AAA_lid PF17852.1 EPS32554.1 - 7.9e-18 64.8 0.4 3.5e-16 59.4 0.0 3.1 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA PF00004.29 EPS32554.1 - 6.3e-15 55.8 0.0 0.0002 21.8 0.0 5.0 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EPS32554.1 - 8.7e-13 48.7 6.4 0.011 16.1 0.0 7.0 7 0 0 7 7 5 2 AAA domain AAA_18 PF13238.6 EPS32554.1 - 2.8e-09 37.6 0.1 0.073 13.6 0.0 5.5 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.6 EPS32554.1 - 6.4e-09 36.4 2.1 1.3 9.4 0.0 7.4 6 0 0 6 6 5 1 AAA ATPase domain AAA_33 PF13671.6 EPS32554.1 - 1.1e-08 35.3 2.0 0.47 10.6 0.1 5.5 5 0 0 5 5 4 3 AAA domain T2SSE PF00437.20 EPS32554.1 - 7e-06 25.3 0.0 0.017 14.2 0.0 3.5 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_29 PF13555.6 EPS32554.1 - 7.2e-05 22.4 0.1 2.3 8.0 0.0 3.6 3 0 0 3 3 3 2 P-loop containing region of AAA domain Mg_chelatase PF01078.21 EPS32554.1 - 8.9e-05 22.0 0.8 0.62 9.4 0.0 3.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_lid_1 PF17857.1 EPS32554.1 - 9e-05 22.6 0.1 0.0046 17.2 0.0 3.7 3 0 0 3 3 2 1 AAA+ lid domain FtsK_SpoIIIE PF01580.18 EPS32554.1 - 0.00033 20.1 0.0 2.1 7.7 0.0 3.7 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_30 PF13604.6 EPS32554.1 - 0.00055 19.7 1.6 30 4.3 0.0 5.2 6 0 0 6 6 4 0 AAA domain AAA_25 PF13481.6 EPS32554.1 - 0.0015 18.1 0.0 0.43 10.1 0.0 3.5 3 0 0 3 3 2 1 AAA domain Rad17 PF03215.15 EPS32554.1 - 0.0027 17.6 0.2 6.7 6.6 0.0 4.5 5 0 0 5 5 3 0 Rad17 P-loop domain ABC_tran PF00005.27 EPS32554.1 - 0.003 18.1 7.4 3.3 8.2 0.0 5.2 5 0 0 5 5 3 2 ABC transporter AAA_19 PF13245.6 EPS32554.1 - 0.0039 17.5 3.3 0.25 11.7 0.0 4.2 5 0 0 5 5 3 1 AAA domain AAA_24 PF13479.6 EPS32554.1 - 0.004 16.9 0.1 27 4.4 0.0 4.3 4 0 0 4 4 3 0 AAA domain IstB_IS21 PF01695.17 EPS32554.1 - 0.0044 16.8 0.8 0.54 10.0 0.0 4.0 4 0 0 4 4 4 1 IstB-like ATP binding protein Zeta_toxin PF06414.12 EPS32554.1 - 0.0077 15.5 0.2 8.5 5.6 0.0 4.1 4 0 0 4 4 4 0 Zeta toxin DUF3867 PF12983.7 EPS32554.1 - 0.018 15.1 0.2 0.018 15.1 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3867) RNA_helicase PF00910.22 EPS32554.1 - 0.021 15.2 0.0 47 4.4 0.0 4.4 4 0 0 4 4 4 0 RNA helicase AAA_21 PF13304.6 EPS32554.1 - 0.024 14.5 0.2 8.6 6.1 0.0 4.0 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system Vps23_core PF09454.10 EPS32554.1 - 0.075 13.0 0.3 4.5 7.3 0.2 3.0 2 0 0 2 2 2 0 Vps23 core domain G-gamma PF00631.22 EPS32554.1 - 0.13 12.2 0.0 2.9 7.9 0.0 3.3 2 0 0 2 2 2 0 GGL domain DUF4482 PF14818.6 EPS32554.1 - 1.8 9.4 13.9 19 6.1 0.0 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) NACHT PF05729.12 EPS32554.1 - 2 8.3 5.4 31 4.4 0.0 4.3 4 0 0 4 4 3 0 NACHT domain DUF2205 PF10224.9 EPS32554.1 - 9.1 6.4 11.9 3.6 7.7 1.2 5.1 3 1 1 4 4 4 0 Short coiled-coil protein Ribonuclease_3 PF00636.26 EPS32555.1 - 7.5e-43 145.4 0.0 8.8e-20 71.3 0.0 3.1 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EPS32555.1 - 2.5e-25 89.1 0.0 1.5e-12 47.8 0.0 3.7 2 2 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.14 EPS32555.1 - 4e-21 75.0 0.0 4.8e-20 71.5 0.0 2.6 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.31 EPS32555.1 - 1.4e-15 57.5 0.1 3.8e-15 56.2 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPS32555.1 - 3e-12 46.9 0.0 8.5e-12 45.4 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EPS32555.1 - 1.6e-11 44.3 0.0 2.9e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_26 PF13500.6 EPS32555.1 - 0.23 11.3 1.0 14 5.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain TAP42 PF04177.12 EPS32556.1 - 1e-105 353.4 8.1 1.2e-105 353.2 8.1 1.0 1 0 0 1 1 1 1 TAP42-like family CpxA_peri PF16527.5 EPS32556.1 - 0.041 14.3 2.1 0.26 11.7 0.7 2.3 1 1 1 2 2 2 0 Two-component sensor protein CpxA, periplasmic domain Sde2_N_Ubi PF13019.6 EPS32556.1 - 0.062 13.1 0.2 0.19 11.5 0.2 1.9 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain Porphobil_deam PF01379.20 EPS32557.1 - 1.7e-70 236.7 0.0 2.6e-70 236.1 0.0 1.3 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 EPS32557.1 - 1.7e-16 60.4 0.4 3.3e-16 59.4 0.4 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Fibrinogen_aC PF12160.8 EPS32557.1 - 0.091 12.6 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Fibrinogen alpha C domain Lon_C PF05362.13 EPS32558.1 - 1.2e-70 237.2 0.2 3.7e-70 235.6 0.1 1.8 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 EPS32558.1 - 6e-29 101.4 0.0 1.1e-28 100.5 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 EPS32558.1 - 1.3e-22 80.7 0.0 3.2e-22 79.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EPS32558.1 - 1.5e-07 31.5 0.0 4.2e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 EPS32558.1 - 7.7e-07 29.0 0.0 1.8e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 EPS32558.1 - 1.9e-06 28.4 0.4 7.6e-06 26.4 0.0 2.3 2 0 0 2 2 1 1 AAA ATPase domain RuvB_N PF05496.12 EPS32558.1 - 0.00017 21.4 0.1 0.00049 19.9 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 EPS32558.1 - 0.0002 21.3 0.0 0.00051 19.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EPS32558.1 - 0.00045 20.5 0.0 0.0048 17.2 0.0 2.6 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.13 EPS32558.1 - 0.0011 18.3 0.0 0.0022 17.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 EPS32558.1 - 0.0017 18.5 0.0 0.0046 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain Birna_VP4 PF01768.16 EPS32558.1 - 0.0021 17.9 0.1 0.0049 16.7 0.1 1.5 1 1 0 1 1 1 1 Birnavirus VP4 protein IstB_IS21 PF01695.17 EPS32558.1 - 0.0028 17.4 0.0 0.008 15.9 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 EPS32558.1 - 0.0087 16.2 0.0 0.026 14.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 EPS32558.1 - 0.027 15.0 0.0 0.083 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EPS32558.1 - 0.031 13.6 0.0 0.063 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.22 EPS32558.1 - 0.04 14.3 0.1 0.29 11.6 0.0 2.3 2 0 0 2 2 2 0 RNA helicase TniB PF05621.11 EPS32558.1 - 0.042 13.3 0.0 0.16 11.4 0.0 2.0 2 0 0 2 2 1 0 Bacterial TniB protein AAA_PrkA PF08298.11 EPS32558.1 - 0.048 12.6 0.0 0.42 9.5 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain AAA_7 PF12775.7 EPS32558.1 - 0.049 13.1 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 EPS32558.1 - 0.05 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Mg_chelatase PF01078.21 EPS32558.1 - 0.055 12.8 0.1 0.13 11.6 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 EPS32558.1 - 0.076 13.3 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EPS32558.1 - 0.082 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EPS32558.1 - 0.1 12.2 0.1 0.24 11.0 0.1 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EPS32558.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 EPS32558.1 - 0.11 12.3 1.7 0.15 11.8 0.1 1.9 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.6 EPS32558.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EPS32558.1 - 0.12 12.3 0.0 0.49 10.3 0.0 2.1 2 0 0 2 2 1 0 NACHT domain Rad17 PF03215.15 EPS32558.1 - 0.13 12.1 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_28 PF13521.6 EPS32558.1 - 0.15 12.3 0.1 0.55 10.5 0.1 1.9 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EPS32558.1 - 0.4 11.2 4.3 0.55 10.7 0.0 2.5 2 1 0 2 2 1 0 AAA domain Rubis-subs-bind PF09273.11 EPS32558.1 - 1.7 9.3 4.9 3.1 8.5 0.2 3.2 2 1 1 3 3 3 0 Rubisco LSMT substrate-binding Ribosomal_L23 PF00276.20 EPS32559.1 - 1e-11 45.0 0.0 2.6e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L23 RIO1 PF01163.22 EPS32560.1 - 1.2e-41 142.4 1.6 3.1e-29 101.9 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.11 EPS32560.1 - 8.6e-33 112.4 0.0 3.8e-32 110.4 0.0 2.0 2 0 0 2 2 2 1 Rio2, N-terminal Kdo PF06293.14 EPS32560.1 - 2.6e-07 30.2 0.1 1.6e-06 27.6 0.0 2.2 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EPS32560.1 - 3.3e-07 30.5 0.1 0.00095 19.1 0.0 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family NOA36 PF06524.12 EPS32560.1 - 0.078 12.3 12.3 0.13 11.6 12.3 1.2 1 0 0 1 1 1 0 NOA36 protein Pox_Ag35 PF03286.14 EPS32560.1 - 0.099 12.4 2.8 0.18 11.6 2.8 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SGT1 PF07093.11 EPS32560.1 - 0.1 11.0 2.9 0.34 9.3 2.9 1.7 2 0 0 2 2 2 0 SGT1 protein BUD22 PF09073.10 EPS32560.1 - 0.23 10.8 8.6 0.73 9.1 7.4 2.0 2 0 0 2 2 2 0 BUD22 HET-S PF17108.5 EPS32560.1 - 0.62 9.9 2.8 0.94 9.3 0.7 2.2 2 0 0 2 2 2 0 N-terminal small S protein of HET, non-prionic Sigma70_ner PF04546.13 EPS32560.1 - 5.4 6.8 10.3 2.6 7.9 7.9 1.6 2 0 0 2 2 2 0 Sigma-70, non-essential region Paf1 PF03985.13 EPS32560.1 - 5.5 5.9 9.6 7.5 5.4 9.6 1.2 1 0 0 1 1 1 0 Paf1 FAM176 PF14851.6 EPS32560.1 - 5.6 6.6 9.4 10 5.7 9.4 1.4 1 0 0 1 1 1 0 FAM176 family Sporozoite_P67 PF05642.11 EPS32560.1 - 9.3 4.2 9.8 14 3.6 9.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.14 EPS32560.1 - 9.5 4.4 13.8 12 4.0 13.8 1.1 1 0 0 1 1 1 0 CDC45-like protein RPN1_RPN2_N PF17781.1 EPS32561.1 - 2.9e-119 398.0 2.2 5e-119 397.3 2.2 1.4 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 EPS32561.1 - 1.4e-29 101.9 0.0 2.5e-29 101.1 0.0 1.4 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 EPS32561.1 - 2.7e-17 62.2 17.4 5.9e-05 23.3 0.3 8.0 8 0 0 8 8 8 4 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EPS32561.1 - 0.00027 21.3 2.7 1.4 9.4 0.0 4.4 5 2 1 6 6 6 3 HEAT repeats Mlh1_C PF16413.5 EPS32562.1 - 3.6e-100 334.8 0.0 8e-100 333.7 0.0 1.6 2 0 0 2 2 2 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 EPS32562.1 - 9.9e-35 118.8 0.2 1.7e-34 118.0 0.2 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 EPS32562.1 - 2.9e-13 49.8 0.0 6.6e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EPS32562.1 - 8.7e-07 29.4 0.0 2.4e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DSPc PF00782.20 EPS32563.1 - 4.6e-29 100.9 0.0 1.3e-20 73.5 0.0 2.5 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EPS32563.1 - 9.1e-05 22.1 0.0 0.0025 17.4 0.0 2.3 2 0 0 2 2 2 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 EPS32563.1 - 0.043 13.5 0.0 8.7 6.0 0.0 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 EPS32563.1 - 0.088 12.9 0.0 0.47 10.6 0.0 2.0 2 0 0 2 2 2 0 Inositol hexakisphosphate Protocadherin PF08374.11 EPS32563.1 - 0.22 11.5 1.5 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 Protocadherin CNH PF00780.22 EPS32565.1 - 0.00013 21.6 0.0 0.022 14.4 0.1 2.4 2 0 0 2 2 2 2 CNH domain ANAPC4_WD40 PF12894.7 EPS32565.1 - 0.00058 20.1 0.0 0.24 11.7 0.0 3.8 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EPS32565.1 - 0.001 19.8 0.1 0.24 12.3 0.0 4.0 5 0 0 5 5 5 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 EPS32565.1 - 0.017 14.2 0.0 0.12 11.4 0.0 2.1 2 0 0 2 2 2 0 Coatomer WD associated region MMS1_N PF10433.9 EPS32565.1 - 0.069 11.8 0.1 2.4 6.7 0.0 2.7 3 0 0 3 3 3 0 Mono-functional DNA-alkylating methyl methanesulfonate N-term Hira PF07569.11 EPS32565.1 - 0.074 12.8 0.1 0.53 10.0 0.0 2.3 3 0 0 3 3 3 0 TUP1-like enhancer of split Ge1_WD40 PF16529.5 EPS32565.1 - 0.11 11.4 0.1 0.51 9.3 0.0 2.0 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Fungal_trans PF04082.18 EPS32566.1 - 1.5e-12 47.2 0.6 2.7e-12 46.3 0.6 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain EF-hand_6 PF13405.6 EPS32567.1 - 3e-08 32.9 0.1 0.004 17.0 0.0 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 EPS32567.1 - 2.2e-05 24.8 0.5 5.3e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EPS32567.1 - 0.0046 16.4 0.0 0.024 14.2 0.0 2.0 2 0 0 2 2 2 1 EF hand SAM_2 PF07647.17 EPS32568.1 - 0.14 12.3 0.0 5.4 7.2 0.0 2.6 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) APG6_N PF17675.1 EPS32568.1 - 8.4 6.9 14.7 8.2 7.0 1.6 3.6 3 0 0 3 3 3 0 Apg6 coiled-coil region OB_NTP_bind PF07717.16 EPS32569.1 - 4.9e-25 87.7 0.1 2e-24 85.7 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EPS32569.1 - 5.5e-20 71.7 0.0 1.5e-19 70.2 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EPS32569.1 - 1.4e-11 44.7 0.0 8.3e-11 42.2 0.0 2.2 3 0 0 3 3 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EPS32569.1 - 1.1e-07 31.8 0.1 2.2e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EPS32569.1 - 4.3e-06 27.1 0.2 1.4e-05 25.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 EPS32569.1 - 0.00019 21.1 0.2 0.00061 19.5 0.2 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.14 EPS32569.1 - 0.0018 18.2 0.1 0.0039 17.2 0.1 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_19 PF13245.6 EPS32569.1 - 0.0022 18.3 0.1 0.0045 17.3 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EPS32569.1 - 0.01 15.6 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EPS32569.1 - 0.012 16.1 0.0 0.027 15.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EPS32569.1 - 0.013 15.0 0.0 0.039 13.5 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region T2SSE PF00437.20 EPS32569.1 - 0.019 14.0 0.0 0.045 12.8 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.15 EPS32569.1 - 0.14 12.1 0.0 9.5 6.2 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PRMT5_TIM PF17285.2 EPS32570.1 - 4.4e-72 242.4 0.0 6.2e-72 241.9 0.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5 PF05185.16 EPS32570.1 - 4.4e-66 222.0 0.0 7.2e-66 221.3 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 EPS32570.1 - 2.4e-58 196.9 0.0 4.1e-58 196.1 0.0 1.4 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Glyco_hydro_16 PF00722.21 EPS32571.1 - 1.3e-40 138.7 3.2 2.9e-40 137.6 3.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 AbLIM_anchor PF16182.5 EPS32571.1 - 0.3 10.9 10.0 0.46 10.3 10.0 1.2 1 0 0 1 1 1 0 Putative adherens-junction anchoring region of AbLIM PV-1 PF06637.11 EPS32572.1 - 0.041 12.7 6.5 0.08 11.8 6.5 1.4 1 0 0 1 1 1 0 PV-1 protein (PLVAP) VPS11_C PF12451.8 EPS32572.1 - 0.33 11.2 4.9 5.5 7.3 0.9 2.8 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal PrmC_N PF17827.1 EPS32572.1 - 3 8.5 5.4 3.2 8.4 3.4 2.2 2 0 0 2 2 2 0 PrmC N-terminal domain zf-C2H2 PF00096.26 EPS32573.1 - 0.00054 20.3 17.9 0.019 15.4 5.7 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 EPS32573.1 - 0.0012 19.4 1.1 1 10.0 0.3 2.6 1 1 1 2 2 2 2 FOXP coiled-coil domain zf-C2H2_4 PF13894.6 EPS32573.1 - 0.36 11.8 12.5 0.58 11.2 3.4 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger ZF-HD_dimer PF04770.12 EPS32573.1 - 0.68 10.3 6.2 1.6 9.2 6.2 1.6 1 1 0 1 1 1 0 ZF-HD protein dimerisation region PAP1 PF08601.10 EPS32573.1 - 2.4 7.8 7.6 0.15 11.8 2.5 1.4 2 0 0 2 2 2 0 Transcription factor PAP1 Pkinase PF00069.25 EPS32574.1 - 4.3e-74 249.2 0.0 5.8e-74 248.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS32574.1 - 1.6e-30 106.2 0.0 8.1e-22 77.7 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EPS32574.1 - 6.9e-07 28.9 0.0 0.4 9.9 0.0 3.2 3 0 0 3 3 3 3 Kinase-like Pkinase_fungal PF17667.1 EPS32574.1 - 0.025 13.4 0.0 0.05 12.4 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EPS32574.1 - 0.031 13.6 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EPS32574.1 - 0.084 12.8 0.0 3.4 7.5 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family DASH_Dad3 PF08656.10 EPS32575.1 - 1.5e-26 92.2 0.8 3e-26 91.3 0.8 1.4 1 0 0 1 1 1 1 DASH complex subunit Dad3 PIN_12 PF16289.5 EPS32575.1 - 0.074 13.5 0.1 0.33 11.4 0.0 1.8 2 0 0 2 2 2 0 PIN domain Ribosomal_S5_C PF03719.15 EPS32576.1 - 1.3e-24 85.5 0.0 2.3e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 EPS32576.1 - 2.2e-16 59.6 0.4 4.3e-16 58.6 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain DUF294_C PF10335.9 EPS32576.1 - 2.4 7.9 5.0 7.7 6.3 0.4 2.7 3 0 0 3 3 3 0 Putative nucleotidyltransferase substrate binding domain tRNA_U5-meth_tr PF05958.11 EPS32577.1 - 6.7e-13 48.4 0.1 1.2e-05 24.5 0.0 2.6 3 0 0 3 3 3 2 tRNA (Uracil-5-)-methyltransferase Methyltransf_25 PF13649.6 EPS32577.1 - 0.0064 17.2 0.0 0.017 15.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPS32577.1 - 0.028 14.2 0.0 0.084 12.7 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.10 EPS32577.1 - 0.081 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 EPS32577.1 - 0.12 11.7 0.1 0.21 11.0 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Actin PF00022.19 EPS32578.1 - 4.2e-88 295.7 0.0 1.4e-85 287.4 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EPS32578.1 - 0.057 12.2 0.0 1.6 7.4 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein Asparaginase_2 PF01112.18 EPS32579.1 - 2.7e-48 164.6 0.1 3.2e-27 95.4 0.0 2.3 2 0 0 2 2 2 2 Asparaginase Tfb4 PF03850.14 EPS32580.1 - 1.8e-119 398.3 0.0 2.1e-119 398.1 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 REF PF05755.12 EPS32580.1 - 0.072 12.9 0.3 0.11 12.3 0.3 1.2 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) UNC45-central PF11701.8 EPS32582.1 - 2.9e-43 147.5 5.5 1.4e-42 145.2 0.4 3.6 4 1 0 4 4 4 1 Myosin-binding striated muscle assembly central Arm PF00514.23 EPS32582.1 - 0.0076 16.3 12.0 0.94 9.6 0.1 6.8 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat GDPD PF03009.17 EPS32583.1 - 2.5e-73 247.0 0.0 1.3e-72 244.6 0.0 2.1 3 0 0 3 3 3 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 EPS32583.1 - 5.6e-40 135.8 0.1 3.3e-16 59.6 0.1 3.8 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPS32583.1 - 4.7e-27 94.0 1.4 4.7e-08 33.4 0.0 5.2 4 1 1 5 5 5 4 Ankyrin repeats (many copies) SPX PF03105.19 EPS32583.1 - 4.5e-22 79.5 9.9 7.3e-10 39.3 0.1 4.0 3 1 1 4 4 4 3 SPX domain Ank_5 PF13857.6 EPS32583.1 - 3.5e-19 68.6 0.1 3.4e-07 30.4 0.0 5.1 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPS32583.1 - 4e-19 66.7 0.2 0.01 16.3 0.0 7.1 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 EPS32583.1 - 4.4e-18 64.8 0.2 0.012 16.0 0.0 6.0 4 1 0 4 4 4 4 Ankyrin repeat CHAD PF05235.14 EPS32583.1 - 4.5 7.2 8.8 0.73 9.8 2.6 2.2 2 0 0 2 2 2 0 CHAD domain Asparaginase PF00710.20 EPS32584.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Asparaginase, N-terminal His_Phos_2 PF00328.22 EPS32585.1 - 6.1e-12 45.6 0.3 1.8e-11 44.0 0.3 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PDGLE PF13190.6 EPS32585.1 - 0.12 12.2 0.0 0.42 10.5 0.0 1.9 1 0 0 1 1 1 0 PDGLE domain FixS PF03597.15 EPS32585.1 - 0.25 11.1 1.6 0.61 9.8 1.6 1.7 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type TRF PF08558.10 EPS32586.1 - 1.2e-86 290.2 0.9 1.8e-86 289.6 0.9 1.3 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 EPS32586.1 - 0.00066 19.8 0.0 0.0013 18.9 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain TFIID_30kDa PF03540.13 EPS32587.1 - 6.5e-22 77.2 0.1 1e-21 76.6 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit FoP_duplication PF13865.6 EPS32587.1 - 2.7 8.6 6.7 0.55 10.8 2.9 1.9 2 1 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Ribosomal_S19 PF00203.21 EPS32588.1 - 7e-25 86.7 0.0 8.4e-25 86.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 IPK PF03770.16 EPS32589.1 - 5.8e-59 199.3 0.0 8.7e-59 198.7 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase Arb1 PF09692.10 EPS32590.1 - 1e-124 416.8 0.0 1.2e-124 416.5 0.0 1.0 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 DUF600 PF04634.12 EPS32590.1 - 0.061 13.4 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF600 ADH_zinc_N PF00107.26 EPS32591.1 - 1.7e-25 89.5 0.0 2.8e-25 88.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPS32591.1 - 4.5e-20 73.0 0.0 7.4e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPS32591.1 - 1.3e-08 34.6 0.0 9.5e-08 31.9 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EPS32591.1 - 0.0077 16.1 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase Sgf11 PF08209.11 EPS32592.1 - 0.025 14.2 1.9 0.16 11.6 0.0 2.8 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) CLP1_N PF16573.5 EPS32593.1 - 1.9e-33 114.5 0.0 3.6e-33 113.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor CLP1_P PF16575.5 EPS32593.1 - 5e-30 104.7 0.0 2.3e-29 102.5 0.0 2.0 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 EPS32593.1 - 1.4e-23 83.5 0.0 2.9e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 ATP_bind_1 PF03029.17 EPS32593.1 - 0.00016 21.5 0.0 0.00045 20.1 0.0 1.7 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 EPS32593.1 - 0.053 13.2 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EPS32593.1 - 0.095 12.8 0.0 0.56 10.3 0.0 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.10 EPS32593.1 - 0.17 11.3 0.0 0.36 10.2 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit KilA-N PF04383.13 EPS32594.1 - 0.00011 22.0 0.1 0.046 13.6 0.0 2.9 2 1 1 3 3 3 2 KilA-N domain Rho_GDI PF02115.17 EPS32595.1 - 1.6e-64 217.3 0.3 1.8e-64 217.1 0.3 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Ribosomal_S16 PF00886.19 EPS32595.1 - 0.15 12.2 0.0 0.33 11.0 0.0 1.6 1 1 0 1 1 1 0 Ribosomal protein S16 Metallophos PF00149.28 EPS32596.1 - 6.2e-37 128.1 0.5 8.1e-37 127.7 0.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EPS32596.1 - 0.036 14.5 0.4 0.11 13.0 0.4 1.8 1 1 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 EPS32596.1 - 0.055 13.7 0.0 0.093 12.9 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Adaptin_N PF01602.20 EPS32597.1 - 4.2e-98 329.2 0.0 5.6e-98 328.8 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EPS32597.1 - 8.4e-16 58.4 0.0 9.4e-14 51.8 0.0 3.5 4 1 1 5 5 5 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EPS32597.1 - 7.9e-10 39.0 0.2 0.0007 19.9 0.0 4.4 3 2 2 5 5 5 3 HEAT repeats HEAT PF02985.22 EPS32597.1 - 3.9e-07 29.8 0.0 0.089 13.1 0.0 4.8 6 0 0 6 6 5 2 HEAT repeat Cohesin_HEAT PF12765.7 EPS32597.1 - 0.018 15.3 0.2 1.1 9.7 0.0 3.6 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion VHS PF00790.19 EPS32597.1 - 0.13 12.1 0.2 18 5.1 0.0 3.1 3 0 0 3 3 3 0 VHS domain HEAT_EZ PF13513.6 EPS32597.1 - 0.21 12.2 4.0 20 5.8 0.0 4.9 6 0 0 6 6 6 0 HEAT-like repeat Nop14 PF04147.12 EPS32597.1 - 1.3 7.2 25.4 2.3 6.3 25.4 1.3 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.12 EPS32597.1 - 1.7 8.3 20.3 3.3 7.4 20.3 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SpoIIIAH PF12685.7 EPS32597.1 - 1.7 8.4 12.3 3.3 7.5 10.9 2.0 2 0 0 2 2 2 0 SpoIIIAH-like protein RNA_pol_3_Rpc31 PF11705.8 EPS32597.1 - 4.4 7.5 21.7 9.8 6.4 21.7 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 YL1 PF05764.13 EPS32597.1 - 5.9 6.9 22.8 11 6.0 22.8 1.5 1 0 0 1 1 1 0 YL1 nuclear protein Nuf2 PF03800.14 EPS32599.1 - 1.2e-43 148.6 0.1 3.2e-43 147.2 0.1 1.8 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 EPS32599.1 - 5.5e-36 123.2 23.3 5.5e-36 123.2 23.3 4.4 3 1 1 4 4 4 1 Designed helical repeat protein 10 domain IF-2B PF01008.17 EPS32600.1 - 1.8e-48 165.2 0.0 2.3e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Helo_like_N PF17111.5 EPS32603.1 - 2.5e-05 23.7 0.4 0.00012 21.5 0.0 2.1 2 0 0 2 2 2 1 Fungal N-terminal domain of STAND proteins Thioredoxin PF00085.20 EPS32604.1 - 2.3e-30 104.6 0.5 2.8e-30 104.3 0.5 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EPS32604.1 - 3.4e-08 33.9 0.3 1.5e-07 31.8 0.3 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 EPS32604.1 - 2.5e-07 30.5 0.0 3.3e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EPS32604.1 - 8.6e-06 26.0 0.0 1.9e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.6 EPS32604.1 - 0.00011 22.3 0.2 0.00022 21.3 0.2 1.5 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 EPS32604.1 - 0.0012 18.5 0.6 0.0069 16.1 0.4 1.9 1 1 1 2 2 2 1 Redoxin OST3_OST6 PF04756.13 EPS32604.1 - 0.0027 17.1 0.1 0.0031 16.9 0.1 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Glutaredoxin PF00462.24 EPS32604.1 - 0.013 15.7 0.1 0.021 15.0 0.1 1.5 1 0 0 1 1 1 0 Glutaredoxin DUF2847 PF11009.8 EPS32604.1 - 0.016 15.1 0.0 0.027 14.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) Thioredoxin_5 PF13743.6 EPS32604.1 - 0.039 13.6 0.1 0.091 12.4 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin MHYT PF03707.16 EPS32606.1 - 6.1e-19 68.0 13.1 3.2e-08 33.6 0.7 3.6 3 0 0 3 3 3 3 Bacterial signalling protein N terminal repeat DUF775 PF05603.12 EPS32607.1 - 6.1e-65 218.5 0.0 6.9e-65 218.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) DUF4743 PF15916.5 EPS32608.1 - 4.5e-13 49.2 0.0 6.7e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 EPS32608.1 - 4e-10 39.9 0.0 6.4e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Beta-lactamase PF00144.24 EPS32609.1 - 1.5e-45 155.9 0.0 2.3e-45 155.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase RNA_pol_Rpb8 PF03870.15 EPS32610.1 - 1e-45 155.4 0.0 1.1e-45 155.2 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 EPS32610.1 - 7.2e-07 29.3 0.0 0.0026 17.8 0.0 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G PAXNEB PF05625.11 EPS32611.1 - 1.8e-116 389.3 0.0 2.2e-116 389.1 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein tRNA_int_endo PF01974.17 EPS32613.1 - 1.4e-13 50.7 0.0 2.9e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain UPF0086 PF01868.16 EPS32614.1 - 1.1e-33 114.9 0.1 1.7e-33 114.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 2OG-FeII_Oxy PF03171.20 EPS32615.1 - 9.9e-13 48.4 0.0 1.9e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EPS32615.1 - 5.6e-12 46.5 0.0 9.7e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Zn_ribbon_17 PF17120.5 EPS32616.1 - 0.11 12.1 27.3 0.041 13.5 3.8 3.2 3 0 0 3 3 3 0 Zinc-ribbon, C4HC2 type DZR PF12773.7 EPS32616.1 - 0.34 11.0 32.6 0.42 10.7 5.7 3.8 2 1 2 4 4 4 0 Double zinc ribbon HypA PF01155.19 EPS32616.1 - 8.5 6.4 26.1 0.69 9.9 3.2 3.3 3 0 0 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cofilin_ADF PF00241.20 EPS32619.1 - 1.6e-12 47.3 0.1 1.9e-12 47.0 0.1 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein MoCF_biosynth PF00994.24 EPS32620.1 - 4.9e-35 120.3 0.0 7.8e-35 119.7 0.0 1.2 1 0 0 1 1 1 1 Probable molybdopterin binding domain Ras PF00071.22 EPS32621.1 - 1.2e-58 197.3 0.1 1.4e-58 197.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EPS32621.1 - 7.5e-20 71.3 0.0 1.1e-19 70.8 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPS32621.1 - 1.2e-07 31.4 0.0 1.3e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EPS32621.1 - 8.4e-06 25.5 0.1 4.9e-05 22.9 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EPS32621.1 - 0.00017 21.5 0.5 0.48 10.3 0.0 2.4 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EPS32621.1 - 0.0032 17.5 0.0 0.0069 16.5 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EPS32621.1 - 0.0078 15.8 0.0 0.013 15.1 0.0 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 EPS32621.1 - 0.013 15.5 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain DUF2075 PF09848.9 EPS32621.1 - 0.082 12.1 0.4 9.4 5.4 0.0 2.0 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 EPS32621.1 - 0.1 12.3 1.0 2.7 7.7 0.2 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein adh_short PF00106.25 EPS32623.1 - 1.9e-54 184.1 0.1 2.5e-54 183.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS32623.1 - 1.5e-36 126.2 0.2 2e-36 125.7 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPS32623.1 - 1.5e-12 47.8 0.0 2.4e-12 47.1 0.0 1.4 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 EPS32623.1 - 0.0036 17.5 0.1 0.0067 16.7 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 EPS32623.1 - 0.0075 15.4 0.1 0.022 13.9 0.1 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EPS32623.1 - 0.019 14.4 0.0 0.062 12.8 0.0 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glyco_hydro_43 PF04616.14 EPS32625.1 - 9e-36 123.7 0.1 1e-35 123.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 RibD_C PF01872.17 EPS32626.1 - 4.5e-34 118.0 0.0 5.4e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain Caps_synth PF05704.12 EPS32627.1 - 2.6e-14 53.3 0.0 4.6e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.15 EPS32627.1 - 0.00016 22.2 0.0 0.00034 21.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif GATA PF00320.27 EPS32628.1 - 8.3e-28 95.7 17.6 2.3e-14 52.7 6.1 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 EPS32628.1 - 2e-05 24.0 2.2 0.014 14.9 0.0 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding Zn-ribbon_8 PF09723.10 EPS32628.1 - 5.5e-05 23.2 2.8 0.1 12.7 0.2 2.7 2 0 0 2 2 2 2 Zinc ribbon domain OrfB_Zn_ribbon PF07282.11 EPS32628.1 - 0.0008 19.3 4.5 0.087 12.8 0.5 2.5 2 0 0 2 2 2 2 Putative transposase DNA-binding domain Auto_anti-p27 PF06677.12 EPS32628.1 - 0.0043 17.2 5.9 0.084 13.0 0.4 2.5 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF-5_eIF-2B PF01873.17 EPS32628.1 - 0.0079 16.1 3.4 1.6 8.7 0.4 2.3 2 0 0 2 2 2 2 Domain found in IF2B/IF5 DZR PF12773.7 EPS32628.1 - 0.023 14.7 10.4 1.2 9.2 0.3 3.0 2 1 1 3 3 3 0 Double zinc ribbon ArfGap PF01412.18 EPS32628.1 - 0.059 13.4 3.4 0.47 10.5 0.1 2.3 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Ribosomal_S27e PF01667.17 EPS32628.1 - 0.16 11.7 1.2 10 5.9 0.2 2.5 2 0 0 2 2 2 0 Ribosomal protein S27 RNHCP PF12647.7 EPS32628.1 - 0.98 9.4 4.4 24 5.0 0.0 2.9 3 0 0 3 3 3 0 RNHCP domain Rubredoxin_2 PF18073.1 EPS32628.1 - 2.5 7.9 10.7 9.7 6.0 0.4 4.4 4 0 0 4 4 4 0 Rubredoxin metal binding domain COPI_assoc PF08507.10 EPS32631.1 - 9.2e-31 106.6 4.8 9.8e-31 106.5 4.8 1.0 1 0 0 1 1 1 1 COPI associated protein UCR_Fe-S_N PF10399.9 EPS32631.1 - 0.034 13.5 0.1 0.16 11.4 0.0 2.1 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Cg6151-P PF10233.9 EPS32631.1 - 0.32 11.3 6.5 0.59 10.5 6.3 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein CG6151-P MFS_MOT1 PF16983.5 EPS32631.1 - 0.84 10.1 7.9 2 8.8 0.2 2.7 1 1 2 3 3 3 0 Molybdate transporter of MFS superfamily ALMT PF11744.8 EPS32631.1 - 1.2 7.9 3.5 1.4 7.6 3.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DAO PF01266.24 EPS32633.1 - 5.8e-34 118.2 0.6 6.7e-34 118.0 0.6 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EPS32633.1 - 7.5e-05 22.9 0.0 0.0002 21.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EPS32633.1 - 0.00018 20.8 0.3 0.00055 19.2 0.0 1.9 2 0 0 2 2 2 1 Thi4 family MRP-S35 PF10246.9 EPS32633.1 - 0.099 12.6 0.0 0.39 10.7 0.0 1.9 2 0 0 2 2 2 0 Mitochondrial ribosomal protein MRP-S35 GMC_oxred_N PF00732.19 EPS32633.1 - 0.15 11.4 0.1 0.42 9.9 0.0 1.8 2 0 0 2 2 2 0 GMC oxidoreductase Glu_dehyd_C PF16912.5 EPS32633.1 - 0.15 11.5 0.0 1.3 8.5 0.0 2.1 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus OTU PF02338.19 EPS32634.1 - 3e-10 40.7 0.0 5.3e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease CUE PF02845.16 EPS32634.1 - 0.013 15.2 0.0 0.027 14.2 0.0 1.6 1 0 0 1 1 1 0 CUE domain DMA PF03474.14 EPS32634.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 DMRTA motif MFS_1 PF07690.16 EPS32635.1 - 7.8e-41 140.2 57.0 7.3e-30 104.1 35.0 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.8 EPS32636.1 - 2.9e-09 36.2 6.1 1.4e-08 34.0 6.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS32636.1 - 0.00048 20.2 9.3 0.00048 20.2 9.3 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 EPS32638.1 - 9.3e-13 48.5 7.7 0.036 14.9 0.1 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat DEAD PF00270.29 EPS32639.1 - 2.7e-43 147.8 0.1 4e-43 147.2 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPS32639.1 - 5.9e-20 71.7 0.1 7.7e-19 68.1 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EPS32639.1 - 1e-18 67.3 0.0 1.9e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EPS32639.1 - 6.9e-06 26.2 0.0 2e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EPS32639.1 - 0.0025 17.1 0.1 0.0095 15.2 0.0 1.9 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase FAM176 PF14851.6 EPS32639.1 - 0.047 13.4 0.2 0.047 13.4 0.2 2.9 3 0 0 3 3 3 0 FAM176 family TLP-20 PF06088.11 EPS32639.1 - 1.5 8.7 3.7 1.6 8.6 0.4 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Pantoate_ligase PF02569.15 EPS32640.1 - 1e-91 306.9 0.0 1.2e-91 306.7 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase ATP-sulfurylase PF01747.17 EPS32640.1 - 0.073 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 ATP-sulfurylase Acyltransferase PF01553.21 EPS32641.1 - 8.3e-17 61.1 0.0 1.8e-16 60.0 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase GDA1_CD39 PF01150.17 EPS32642.1 - 6.6e-105 351.2 0.0 8.8e-105 350.8 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family IKKbetaNEMObind PF12179.8 EPS32642.1 - 0.036 14.1 0.2 0.086 12.9 0.2 1.6 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain LRR_9 PF14580.6 EPS32643.1 - 2.4e-59 199.8 0.4 4e-59 199.0 0.4 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 EPS32643.1 - 3.5e-07 29.9 7.1 3.5e-07 29.9 7.1 2.3 2 1 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 EPS32643.1 - 0.00035 20.9 14.5 0.0029 18.0 3.0 3.2 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) DUF4349 PF14257.6 EPS32643.1 - 0.005 16.3 1.7 0.0084 15.6 1.7 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) HTH_38 PF13936.6 EPS32643.1 - 0.0061 16.3 0.5 0.012 15.4 0.5 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain T4_Gp59_C PF08994.10 EPS32643.1 - 0.009 16.6 0.0 0.015 15.9 0.0 1.3 1 0 0 1 1 1 1 T4 gene Gp59 loader of gp41 DNA helicase C-term MNR PF15718.5 EPS32643.1 - 0.023 12.9 0.1 0.031 12.4 0.1 1.0 1 0 0 1 1 1 0 Protein moonraker EIAV_Rev PF11129.8 EPS32643.1 - 0.14 12.3 0.1 0.23 11.7 0.1 1.3 1 0 0 1 1 1 0 Rev protein of equine infectious anaemia virus FAD_binding_4 PF01565.23 EPS32646.1 - 9e-19 67.6 0.5 1.8e-18 66.6 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EPS32646.1 - 0.0075 16.3 0.0 0.023 14.8 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like ADH_zinc_N PF00107.26 EPS32647.1 - 1.9e-22 79.6 0.0 3.3e-22 78.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPS32647.1 - 6.6e-17 62.8 0.0 1.3e-16 61.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPS32647.1 - 3.6e-08 33.3 0.1 4.3e-07 29.8 0.1 2.3 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Peptidase_M73 PF12389.8 EPS32647.1 - 0.16 11.8 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Camelysin metallo-endopeptidase Amidohydro_1 PF01979.20 EPS32649.1 - 2.7e-42 145.3 0.0 3.2e-42 145.1 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EPS32649.1 - 2.3e-15 57.1 0.1 2.4e-09 37.2 0.0 2.4 2 1 0 2 2 2 2 Amidohydrolase family DHO_dh PF01180.21 EPS32649.1 - 0.09 12.0 0.1 0.14 11.3 0.1 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase MFS_1 PF07690.16 EPS32650.1 - 7.2e-40 137.0 56.8 3.6e-39 134.7 55.1 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily FTR1 PF03239.14 EPS32651.1 - 4.9e-88 295.2 6.9 6.2e-88 294.9 6.9 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF3087 PF11286.8 EPS32651.1 - 0.18 11.2 0.1 0.53 9.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) YitT_membrane PF02588.15 EPS32651.1 - 0.35 10.2 10.1 0.098 12.0 0.5 2.8 2 1 1 3 3 3 0 Uncharacterised 5xTM membrane BCR, YitT family COG1284 DUF3180 PF11377.8 EPS32651.1 - 0.57 10.3 11.6 0.37 10.9 1.6 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3180) Wzy_C PF04932.15 EPS32651.1 - 4.6 6.8 12.7 0.9 9.2 2.4 3.1 1 1 1 2 2 2 0 O-Antigen ligase Cu-oxidase_2 PF07731.14 EPS32652.1 - 1.4e-44 151.2 12.1 1.2e-40 138.4 0.5 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EPS32652.1 - 9.5e-40 135.3 4.5 1.4e-37 128.3 3.2 2.8 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 EPS32652.1 - 6.2e-36 123.9 6.0 4.2e-33 114.7 0.6 3.2 3 0 0 3 3 3 2 Multicopper oxidase RSN1_7TM PF02714.15 EPS32657.1 - 2.6e-90 302.5 17.9 2.6e-90 302.5 17.9 3.2 3 0 0 3 3 3 2 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EPS32657.1 - 4.2e-41 140.3 5.3 4.2e-41 140.3 5.3 2.5 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EPS32657.1 - 1e-36 126.8 0.5 1.8e-36 126.0 0.5 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 EPS32657.1 - 1.6e-32 111.5 0.5 3.7e-32 110.4 0.5 1.6 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter ZapB PF06005.12 EPS32657.1 - 0.49 10.9 1.8 0.68 10.4 0.0 2.1 2 0 0 2 2 2 0 Cell division protein ZapB Fungal_trans_2 PF11951.8 EPS32658.1 - 0.00037 19.4 1.0 0.0079 15.1 0.0 2.4 1 1 1 2 2 2 1 Fungal specific transcription factor domain Trans_reg_C PF00486.28 EPS32658.1 - 0.037 14.1 0.2 1.9 8.6 0.0 3.1 3 0 0 3 3 3 0 Transcriptional regulatory protein, C terminal TPR_12 PF13424.6 EPS32658.1 - 0.11 12.9 0.2 0.11 12.9 0.2 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat MCM PF00493.23 EPS32659.1 - 8.9e-97 322.6 0.0 1.4e-96 321.9 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EPS32659.1 - 2.8e-38 130.6 0.1 6.6e-38 129.4 0.1 1.6 1 0 0 1 1 1 1 MCM OB domain MCM6_C PF18263.1 EPS32659.1 - 1e-32 112.6 3.0 2.5e-32 111.3 3.0 1.7 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 EPS32659.1 - 1.3e-26 92.8 0.2 2.9e-26 91.7 0.2 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EPS32659.1 - 2.7e-21 76.1 0.2 9.6e-21 74.3 0.2 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EPS32659.1 - 8.5e-05 22.0 0.0 0.001 18.5 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EPS32659.1 - 0.0047 16.8 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EPS32659.1 - 0.0054 16.5 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 EPS32659.1 - 0.0058 16.6 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) GIDA_assoc PF13932.6 EPS32659.1 - 0.036 14.3 1.2 0.073 13.3 1.2 1.5 1 0 0 1 1 1 0 GidA associated domain LCD1 PF09798.9 EPS32661.1 - 1.2 7.6 3.9 1.5 7.3 3.9 1.0 1 0 0 1 1 1 0 DNA damage checkpoint protein NPR1_interact PF15699.5 EPS32662.1 - 0.11 13.2 0.4 0.11 13.2 0.4 1.9 2 0 0 2 2 2 0 NPR1 interacting Zip PF02535.22 EPS32662.1 - 2.7 7.1 4.3 2.9 7.0 4.3 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Fungal_trans_2 PF11951.8 EPS32664.1 - 6.4e-28 97.6 0.1 2.3e-26 92.5 0.1 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS32664.1 - 0.0011 19.1 11.8 0.0017 18.4 11.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4281 PF14108.6 EPS32664.1 - 0.56 10.6 3.1 7.9 6.9 3.1 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4281) DUF3445 PF11927.8 EPS32665.1 - 1.5e-77 260.3 0.0 1.7e-77 260.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) PUL PF08324.11 EPS32666.1 - 7.4e-69 232.1 0.7 1e-68 231.6 0.7 1.1 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.14 EPS32666.1 - 1.7e-42 144.8 0.0 3e-42 144.0 0.0 1.4 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.20 EPS32666.1 - 2.9e-15 56.1 0.0 5.5e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 EPS32666.1 - 0.00053 19.9 0.0 0.00089 19.1 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 EPS32666.1 - 0.0048 17.3 0.2 0.039 14.4 0.2 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 EPS32666.1 - 0.012 15.6 0.0 0.031 14.3 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin domain OST3_OST6 PF04756.13 EPS32666.1 - 0.075 12.4 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family EF-hand_9 PF14658.6 EPS32667.1 - 0.073 13.4 0.0 5.5 7.4 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain RRM_1 PF00076.22 EPS32668.1 - 3e-14 52.6 0.0 4.8e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EPS32668.1 - 9e-06 25.5 0.0 1.6e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif FoP_duplication PF13865.6 EPS32668.1 - 1.9e-05 25.1 0.6 1.9e-05 25.1 0.6 2.6 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 RRM_7 PF16367.5 EPS32668.1 - 0.059 13.5 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif AOC_like PF18678.1 EPS32668.1 - 0.13 11.8 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Allene oxide cyclase barrel like domain Snf7 PF03357.21 EPS32669.1 - 7.6e-19 68.0 13.6 7.6e-19 68.0 13.6 1.8 1 1 1 2 2 2 1 Snf7 NAGLU_C PF12972.7 EPS32669.1 - 0.023 14.2 0.8 0.035 13.6 0.8 1.3 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain BMFP PF04380.13 EPS32669.1 - 0.076 13.5 7.6 0.2 12.1 0.9 3.9 3 1 0 4 4 4 0 Membrane fusogenic activity Tcell_CD4_C PF12104.8 EPS32669.1 - 0.18 11.7 0.2 0.18 11.7 0.2 2.2 2 0 0 2 2 2 0 T cell CD4 receptor C terminal region MerR-DNA-bind PF09278.11 EPS32669.1 - 0.19 12.3 11.2 6.4 7.4 0.5 3.8 3 1 0 3 3 3 0 MerR, DNA binding Gon7 PF08738.10 EPS32669.1 - 0.3 11.2 7.5 0.66 10.1 3.9 2.4 2 1 0 2 2 2 0 Gon7 family TPR_MLP1_2 PF07926.12 EPS32669.1 - 2.1 8.4 16.3 0.025 14.6 4.9 2.9 2 2 0 2 2 2 0 TPR/MLP1/MLP2-like protein Spectrin PF00435.21 EPS32669.1 - 2.9 8.4 10.7 0.52 10.8 1.3 3.2 2 2 0 2 2 2 0 Spectrin repeat CS PF04969.16 EPS32670.1 - 3.5e-07 31.2 0.1 5.6e-07 30.5 0.1 1.4 1 1 0 1 1 1 1 CS domain PIH1_CS PF18201.1 EPS32670.1 - 0.012 16.0 0.0 0.36 11.3 0.0 2.1 1 1 0 1 1 1 0 PIH1 CS-like domain Iwr1 PF08574.10 EPS32670.1 - 0.084 13.9 1.6 0.084 13.9 1.6 2.2 3 0 0 3 3 3 0 Transcription factor Iwr1 DFRP_C PF16543.5 EPS32671.1 - 3.2e-26 91.6 10.0 3.2e-26 91.6 10.0 4.3 3 2 2 5 5 5 1 DRG Family Regulatory Proteins, Tma46 zf-CCCH PF00642.24 EPS32671.1 - 0.00035 20.4 2.4 0.00035 20.4 2.4 2.6 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EPS32671.1 - 0.00071 19.3 9.9 0.015 15.1 2.9 3.3 3 0 0 3 3 3 1 CCCH-type zinc finger Torus PF16131.5 EPS32671.1 - 0.0012 19.5 5.9 0.0012 19.5 5.9 3.9 2 2 2 4 4 4 2 Torus domain zf-CCCH_3 PF15663.5 EPS32671.1 - 0.006 16.8 0.5 0.44 10.8 0.2 2.6 2 0 0 2 2 2 1 Zinc-finger containing family zf_CCCH_4 PF18345.1 EPS32671.1 - 0.015 15.3 7.4 0.015 15.3 7.4 3.1 3 0 0 3 3 3 0 Zinc finger domain zf-CCCH_2 PF14608.6 EPS32671.1 - 0.21 12.1 13.1 0.54 10.8 4.1 2.9 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger DAO PF01266.24 EPS32672.1 - 2.5e-30 106.3 0.1 2.8e-30 106.1 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPS32672.1 - 0.045 13.0 0.1 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EPS32672.1 - 0.13 11.3 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 EPS32672.1 - 0.14 12.8 0.1 0.29 11.7 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF737 PF05300.11 EPS32675.1 - 1.7 9.0 10.7 3.4 8.0 10.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF737) adh_short PF00106.25 EPS32676.1 - 2.9e-24 85.6 0.0 4e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS32676.1 - 9.8e-23 80.9 0.0 1.3e-22 80.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPS32676.1 - 8.8e-08 32.3 0.0 1.4e-07 31.6 0.0 1.4 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 EPS32676.1 - 0.0038 16.6 0.0 0.0047 16.3 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) zf-HIT PF04438.16 EPS32677.1 - 2.3e-10 40.1 10.4 4.1e-10 39.4 10.4 1.4 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 EPS32677.1 - 1.6 8.9 7.6 3.5 7.8 7.6 1.6 1 0 0 1 1 1 0 MYND finger Atg14 PF10186.9 EPS32678.1 - 0.0011 18.1 1.0 0.0011 18.1 1.0 2.0 1 1 1 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 EPS32678.1 - 0.0022 18.0 7.0 0.37 10.8 0.7 3.1 1 1 2 3 3 3 2 Protein of unknown function (DUF1664) PDDEXK_1 PF12705.7 EPS32678.1 - 0.0035 17.3 0.2 0.0092 15.9 0.1 1.7 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily Spc7 PF08317.11 EPS32678.1 - 0.0052 15.7 1.2 0.0095 14.8 1.2 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein AAA_13 PF13166.6 EPS32678.1 - 0.014 14.1 0.3 0.029 13.0 0.1 1.5 1 1 0 1 1 1 0 AAA domain DUF1640 PF07798.11 EPS32678.1 - 0.027 14.5 7.3 0.2 11.7 1.7 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1640) KASH_CCD PF14662.6 EPS32678.1 - 0.028 14.2 4.0 0.16 11.8 4.0 2.0 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF4472 PF14739.6 EPS32678.1 - 0.029 15.1 1.5 3.6 8.4 0.1 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4472) DUF641 PF04859.12 EPS32678.1 - 0.049 14.0 2.9 0.22 11.8 0.7 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) TSC22 PF01166.18 EPS32678.1 - 0.052 13.9 0.1 0.47 10.8 0.0 2.6 2 1 0 3 3 3 0 TSC-22/dip/bun family Macoilin PF09726.9 EPS32678.1 - 0.061 11.9 3.4 0.098 11.2 2.8 1.6 1 1 0 1 1 1 0 Macoilin family DUF4763 PF15960.5 EPS32678.1 - 0.076 12.3 8.0 0.25 10.6 0.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) DUF724 PF05266.14 EPS32678.1 - 0.1 12.4 0.4 0.27 11.0 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Baculo_PEP_C PF04513.12 EPS32678.1 - 0.12 12.4 8.9 0.29 11.1 4.9 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4795 PF16043.5 EPS32678.1 - 0.16 11.6 2.5 0.32 10.6 2.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) TolA_bind_tri PF16331.5 EPS32678.1 - 0.21 11.7 5.4 9.7 6.4 0.2 3.6 2 1 1 3 3 3 0 TolA binding protein trimerisation HMMR_N PF15905.5 EPS32678.1 - 0.3 10.5 2.4 0.78 9.2 2.4 1.7 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF5082 PF16888.5 EPS32678.1 - 0.35 11.1 4.4 3.6 7.9 1.5 2.6 1 1 0 2 2 2 0 Domain of unknown function (DUF5082) Fez1 PF06818.15 EPS32678.1 - 0.4 11.1 3.5 4.7 7.6 3.6 2.2 1 1 0 1 1 1 0 Fez1 Fib_alpha PF08702.10 EPS32678.1 - 0.55 10.4 7.7 3.3 7.9 0.8 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family CENP-F_leu_zip PF10473.9 EPS32678.1 - 0.57 10.2 4.6 0.94 9.5 1.0 2.8 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CLZ PF16526.5 EPS32678.1 - 0.7 10.3 4.6 14 6.2 0.9 3.7 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CdvA PF18822.1 EPS32678.1 - 0.74 9.7 3.0 4.9 7.0 0.2 3.1 2 2 2 4 4 4 0 CdvA-like coiled-coil domain TMF_TATA_bd PF12325.8 EPS32678.1 - 0.75 10.0 3.9 3.2 8.0 0.2 2.7 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding LPP PF04728.13 EPS32678.1 - 1 9.8 8.6 5.3 7.5 0.2 4.5 2 1 2 4 4 4 0 Lipoprotein leucine-zipper YabA PF06156.13 EPS32678.1 - 1.1 10.0 3.2 5.3 7.7 0.4 2.7 1 1 1 2 2 2 0 Initiation control protein YabA Filament PF00038.21 EPS32678.1 - 4.9 6.6 8.1 1.7 8.1 1.9 2.1 1 1 0 2 2 2 0 Intermediate filament protein Peptidase_C48 PF02902.19 EPS32680.1 - 4.5e-26 92.0 0.0 6.5e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Glyco_hydro_18 PF00704.28 EPS32682.1 - 7.2e-64 216.5 0.4 1.5e-63 215.4 0.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.19 EPS32682.1 - 9.1e-10 38.9 54.6 1.6e-09 38.1 7.4 7.4 7 0 0 7 7 7 3 Chitin recognition protein Pectate_lyase_3 PF12708.7 EPS32683.1 - 5.1e-74 248.7 3.9 1.3e-57 195.1 0.3 2.7 2 0 0 2 2 2 2 Pectate lyase superfamily protein LysM PF01476.20 EPS32683.1 - 2e-06 27.7 0.0 0.0073 16.3 0.0 3.3 3 0 0 3 3 3 2 LysM domain End_N_terminal PF12218.8 EPS32683.1 - 5.7e-06 25.9 0.1 0.081 12.6 0.0 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase PAP2 PF01569.21 EPS32686.1 - 8.6e-18 64.4 3.0 8.6e-18 64.4 3.0 1.7 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 EPS32686.1 - 0.0056 16.4 7.9 0.043 13.5 7.9 2.4 1 1 0 1 1 1 1 PAP2 superfamily Ras PF00071.22 EPS32688.1 - 7.6e-49 165.4 0.0 9.2e-49 165.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EPS32688.1 - 3.1e-21 75.8 0.0 4.7e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPS32688.1 - 2e-05 24.1 0.0 6.5e-05 22.5 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_7 PF12775.7 EPS32688.1 - 0.017 14.7 0.0 0.03 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region SRPRB PF09439.10 EPS32688.1 - 0.019 14.4 0.0 0.03 13.8 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DASH_Dad1 PF08649.10 EPS32689.1 - 6.8e-26 90.2 4.7 8.7e-26 89.9 4.7 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.10 EPS32689.1 - 0.0026 17.7 0.7 0.0036 17.2 0.7 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad4 LSM PF01423.22 EPS32692.1 - 2e-18 65.9 0.0 2.2e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF866 PF05907.13 EPS32693.1 - 1.2e-63 213.7 0.7 1.3e-63 213.5 0.7 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) zf-PHD-like PF15446.6 EPS32693.1 - 0.0028 17.3 0.1 0.0034 17.0 0.1 1.1 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain DUF5021 PF16424.5 EPS32693.1 - 0.13 12.0 0.1 0.19 11.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5021) FAD_binding_3 PF01494.19 EPS32694.1 - 2.7e-73 247.2 0.0 3.5e-73 246.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EPS32694.1 - 5.4e-38 130.6 0.1 1e-37 129.7 0.1 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.14 EPS32694.1 - 0.00028 20.2 0.0 0.095 11.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EPS32694.1 - 0.013 15.0 0.1 0.16 11.5 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 EPS32694.1 - 0.042 14.4 0.0 0.15 12.6 0.0 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPS32694.1 - 0.051 13.8 0.0 0.17 12.2 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain UDPG_MGDP_dh_N PF03721.14 EPS32694.1 - 0.082 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Lycopene_cycl PF05834.12 EPS32694.1 - 0.1 11.6 0.0 0.4 9.7 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein PgaD PF13994.6 EPS32696.1 - 0.063 13.3 0.5 0.14 12.2 0.1 1.7 2 1 0 2 2 2 0 PgaD-like protein DDHD PF02862.17 EPS32698.1 - 1.3e-25 90.9 0.0 1.6e-15 57.9 0.0 3.3 2 1 1 3 3 3 2 DDHD domain CBM-like PF14683.6 EPS32699.1 - 1.1e-38 132.7 0.0 2.6e-38 131.5 0.0 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.6 EPS32699.1 - 1.5e-13 50.3 0.3 6.1e-13 48.3 0.3 2.1 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.6 EPS32699.1 - 1.6e-06 28.3 0.2 4.8e-06 26.7 0.1 1.9 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 EPS32699.1 - 0.04 13.9 0.0 0.24 11.4 0.1 2.3 2 1 0 2 2 2 0 CarboxypepD_reg-like domain MoCF_biosynth PF00994.24 EPS32701.1 - 5.1e-47 159.1 0.0 3.9e-23 81.7 0.0 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.17 EPS32701.1 - 1.5e-38 132.0 2.3 3.3e-38 130.9 2.3 1.6 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 EPS32701.1 - 2.8e-15 56.2 0.1 7.8e-15 54.8 0.1 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) SelP_N PF04592.14 EPS32701.1 - 2 7.8 17.1 3.2 7.1 17.1 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region ATP-synt_C PF00137.21 EPS32702.1 - 9.3e-27 93.2 28.4 1.1e-15 57.7 13.7 2.4 2 0 0 2 2 2 2 ATP synthase subunit C Oxidored_q2 PF00420.24 EPS32702.1 - 0.025 14.2 0.3 0.025 14.2 0.3 2.6 3 1 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Ras PF00071.22 EPS32703.1 - 2.7e-59 199.4 0.2 3.5e-59 199.0 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EPS32703.1 - 4.2e-37 127.0 0.4 7.9e-37 126.1 0.1 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPS32703.1 - 1.4e-17 63.7 0.1 1.7e-17 63.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EPS32703.1 - 1.9e-06 27.9 0.3 0.0016 18.3 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EPS32703.1 - 4.5e-06 26.3 0.1 2.9e-05 23.7 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EPS32703.1 - 5.7e-06 25.9 0.0 8.4e-06 25.3 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EPS32703.1 - 1.5e-05 25.1 0.0 2.4e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EPS32703.1 - 4.2e-05 23.0 0.2 5.4e-05 22.7 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region TIR_2 PF13676.6 EPS32703.1 - 0.087 13.4 0.0 0.15 12.7 0.0 1.4 1 0 0 1 1 1 0 TIR domain AAA_7 PF12775.7 EPS32703.1 - 0.092 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region MFS_1 PF07690.16 EPS32704.1 - 4.9e-42 144.1 40.8 4.9e-42 144.1 40.8 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS32704.1 - 2.1e-11 43.4 8.5 2.1e-11 43.4 8.5 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter Kei1 PF08552.11 EPS32705.1 - 1e-69 234.3 2.5 1.2e-69 234.0 2.5 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 NIR_SIR PF01077.22 EPS32707.1 - 8.2e-52 174.9 0.0 1.2e-44 151.6 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 EPS32707.1 - 8.5e-28 96.0 0.0 5e-13 48.7 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 EPS32707.1 - 5e-25 88.4 0.0 1.1e-24 87.3 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.19 EPS32707.1 - 5.2e-06 26.4 0.5 1.5e-05 24.9 0.1 1.9 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg RNA_pol PF00940.19 EPS32708.1 - 4e-185 615.5 0.0 5.6e-185 615.1 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 EPS32708.1 - 4.9e-89 299.0 0.2 7.7e-89 298.4 0.2 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Sin_N PF04801.13 EPS32709.1 - 2.1e-22 80.0 0.0 7.8e-22 78.1 0.0 1.7 1 1 0 1 1 1 1 Sin-like protein conserved region adh_short_C2 PF13561.6 EPS32710.1 - 9.8e-50 169.3 0.1 1.2e-49 169.0 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPS32710.1 - 5.5e-37 127.1 0.9 6.5e-37 126.9 0.1 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EPS32710.1 - 4.4e-08 33.3 0.1 6.5e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPS32710.1 - 0.0038 16.7 0.1 0.0082 15.6 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EPS32710.1 - 0.014 14.5 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EPS32710.1 - 0.046 12.7 0.1 0.059 12.4 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family UPRTase PF14681.6 EPS32710.1 - 0.12 11.8 0.0 0.38 10.2 0.0 1.7 1 1 1 2 2 2 0 Uracil phosphoribosyltransferase adh_short_C2 PF13561.6 EPS32711.1 - 2.6e-59 200.6 3.2 3e-59 200.4 3.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPS32711.1 - 2.7e-42 144.5 2.5 3.4e-42 144.1 2.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPS32711.1 - 9.5e-16 58.2 2.0 1.3e-15 57.8 2.0 1.1 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.21 EPS32711.1 - 0.014 15.5 1.8 0.024 14.7 1.8 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ApoL PF05461.11 EPS32711.1 - 0.017 14.4 0.6 0.022 14.1 0.6 1.1 1 0 0 1 1 1 0 Apolipoprotein L NAD_Gly3P_dh_N PF01210.23 EPS32711.1 - 0.021 14.8 0.3 0.034 14.1 0.3 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DapB_N PF01113.20 EPS32711.1 - 0.044 13.9 0.8 0.17 12.0 1.1 1.8 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Sacchrp_dh_NADP PF03435.18 EPS32711.1 - 0.046 14.0 1.1 2.3 8.5 0.1 2.3 1 1 1 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EPS32711.1 - 0.056 12.9 0.6 0.3 10.5 0.2 2.0 1 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 EPS32711.1 - 0.069 13.0 1.2 0.12 12.3 1.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_31 PF13847.6 EPS32711.1 - 0.08 12.7 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase domain DAP_B PF07930.12 EPS32712.1 - 4.5e-72 241.9 0.0 6.3e-72 241.4 0.0 1.2 1 0 0 1 1 1 1 D-aminopeptidase, domain B Beta-lactamase PF00144.24 EPS32712.1 - 6e-46 157.2 0.0 9.6e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Fungal_trans PF04082.18 EPS32714.1 - 1.9e-38 132.0 0.0 1.9e-38 132.0 0.0 1.7 2 0 0 2 2 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS32714.1 - 3.3e-09 36.7 9.1 5.6e-09 36.0 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EPL1 PF10513.9 EPS32714.1 - 0.05 14.0 6.6 0.075 13.4 5.5 1.9 2 0 0 2 2 1 0 Enhancer of polycomb-like Spt20 PF12090.8 EPS32714.1 - 0.25 10.9 30.7 1.2 8.7 30.9 1.9 2 0 0 2 2 2 0 Spt20 family PAT1 PF09770.9 EPS32714.1 - 1.7 6.8 19.4 2.9 6.0 19.4 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4770 PF15994.5 EPS32714.1 - 2 8.7 9.3 4 7.6 9.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) eIF-3_zeta PF05091.12 EPS32714.1 - 2 7.3 12.0 2.9 6.8 12.0 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CPSF100_C PF13299.6 EPS32714.1 - 2.3 8.4 5.5 5.4 7.2 5.5 1.6 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Presenilin PF01080.17 EPS32714.1 - 3.1 6.5 11.5 5.9 5.6 11.5 1.4 1 0 0 1 1 1 0 Presenilin GREB1 PF15782.5 EPS32714.1 - 3.8 4.5 11.1 5.1 4.1 11.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4707 PF15806.5 EPS32714.1 - 7.9 5.3 7.5 0.2 10.5 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4707) DUF4834 PF16118.5 EPS32714.1 - 8.9 7.3 11.5 37 5.4 11.5 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF4407 PF14362.6 EPS32714.1 - 9.3 5.5 15.7 16 4.7 15.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Radical_SAM PF04055.21 EPS32715.1 - 7.5e-09 36.2 0.0 1.1e-08 35.6 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 EPS32715.1 - 0.00018 21.8 0.0 0.00034 20.9 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EPS32715.1 - 0.026 14.7 0.1 0.077 13.1 0.0 1.7 2 0 0 2 2 2 0 4Fe-4S single cluster domain DUF92 PF01940.16 EPS32716.1 - 1.6e-80 269.9 9.5 1.9e-80 269.7 9.5 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 CsoS2_M PF12288.8 EPS32716.1 - 0.031 13.7 0.1 0.044 13.2 0.1 1.2 1 0 0 1 1 1 0 Carboxysome shell peptide mid-region PHO4 PF01384.20 EPS32719.1 - 1.1e-101 340.2 19.7 1.3e-101 340.0 19.7 1.0 1 0 0 1 1 1 1 Phosphate transporter family PgpA PF04608.13 EPS32719.1 - 0.095 12.7 4.9 0.24 11.4 1.8 2.7 2 0 0 2 2 2 0 Phosphatidylglycerophosphatase A UPF0444 PF15475.6 EPS32719.1 - 2.4 8.5 8.9 1.6 9.1 0.6 2.9 2 0 0 2 2 2 0 Transmembrane protein C12orf23, UPF0444 SLAC1 PF03595.17 EPS32720.1 - 2.7e-62 210.9 42.4 3e-62 210.8 42.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel TPR_2 PF07719.17 EPS32722.1 - 0.011 15.8 1.7 3.8 7.8 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Csm1_N PF18504.1 EPS32722.1 - 0.084 13.2 0.1 0.22 11.9 0.1 1.7 1 0 0 1 1 1 0 Csm1 N-terminal domain TPR_4 PF07721.14 EPS32722.1 - 1.9 9.3 4.5 3.5 8.5 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Methyltransf_33 PF10017.9 EPS32723.1 - 6.4e-85 285.0 0.0 8.9e-85 284.5 0.0 1.1 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.16 EPS32723.1 - 8.8e-23 81.2 2.8 2.4e-21 76.5 2.8 2.2 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 EPS32723.1 - 1.3e-08 35.4 0.4 3.7e-08 33.9 0.1 1.9 2 0 0 2 2 2 1 DinB superfamily GBP_PSP PF02425.15 EPS32723.1 - 0.084 12.5 0.1 0.3 10.8 0.0 2.0 2 0 0 2 2 2 0 Paralytic/GBP/PSP peptide DUF222 PF02720.17 EPS32723.1 - 0.098 12.1 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF222) BNIP2 PF12496.8 EPS32725.1 - 1.1 9.7 10.1 0.35 11.3 5.9 2.4 2 1 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 TFIIA_gamma_C PF02751.14 EPS32726.1 - 1e-25 89.6 2.2 1.6e-25 88.9 2.2 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 EPS32726.1 - 4.7e-24 84.1 0.1 6.5e-24 83.7 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain Hexokinase_1 PF00349.21 EPS32728.1 - 3e-61 206.8 0.0 4.2e-61 206.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 EPS32728.1 - 1.3e-44 152.5 0.0 7.1e-44 150.0 0.0 2.0 1 1 0 1 1 1 1 Hexokinase GILT PF03227.16 EPS32729.1 - 1.1e-13 51.4 0.6 4.2e-13 49.5 0.3 2.0 1 1 1 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) U62_UL91 PF17442.2 EPS32730.1 - 0.023 14.7 0.1 0.11 12.5 0.1 2.2 2 0 0 2 2 2 0 Functional domain of U62 and UL91 proteins WH1 PF00568.23 EPS32730.1 - 0.13 12.2 0.1 0.23 11.4 0.1 1.3 1 0 0 1 1 1 0 WH1 domain MFS_1 PF07690.16 EPS32731.1 - 1.1e-31 110.1 28.5 1.1e-31 110.1 28.5 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily adh_short_C2 PF13561.6 EPS32732.1 - 4.4e-54 183.5 0.4 5.7e-54 183.1 0.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPS32732.1 - 1.7e-45 154.9 0.1 2.1e-45 154.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPS32732.1 - 8e-14 51.9 0.5 1.2e-13 51.4 0.5 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPS32732.1 - 0.0025 17.3 0.3 0.0058 16.1 0.3 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.15 EPS32732.1 - 0.039 14.1 0.0 0.31 11.2 0.0 2.1 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase CHASE3 PF05227.13 EPS32732.1 - 0.056 13.3 0.3 0.1 12.5 0.3 1.4 1 0 0 1 1 1 0 CHASE3 domain GCP_N_terminal PF17681.1 EPS32733.1 - 1.8e-29 103.3 0.0 4.7e-29 102.0 0.0 1.6 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EPS32733.1 - 1.6e-22 80.4 0.0 3.4e-22 79.3 0.0 1.5 1 1 0 1 1 1 1 Gamma tubulin complex component C-terminal ThiF PF00899.21 EPS32734.1 - 6e-110 366.4 0.0 4.1e-74 249.0 0.0 2.5 2 1 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 EPS32734.1 - 1.2e-97 326.8 0.9 4.7e-97 324.8 0.3 2.0 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 EPS32734.1 - 7.4e-30 103.0 0.1 1.6e-29 101.9 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 EPS32734.1 - 2.7e-29 101.7 0.1 5.9e-29 100.6 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin fold domain E1_4HB PF16191.5 EPS32734.1 - 1e-25 89.7 0.8 3.4e-25 88.0 0.7 2.1 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle DUF3891 PF13030.6 EPS32735.1 - 0.019 14.8 0.1 0.02 14.7 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3891) GST_N_2 PF13409.6 EPS32736.1 - 8.7e-24 83.6 0.1 3e-23 81.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EPS32736.1 - 5.7e-17 61.5 0.0 1.3e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EPS32736.1 - 2.2e-06 27.8 0.1 6.4e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EPS32736.1 - 0.00053 20.3 0.0 0.019 15.3 0.0 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EPS32736.1 - 0.0026 17.9 0.1 0.006 16.7 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EPS32736.1 - 0.027 15.1 0.0 0.046 14.3 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain QIL1 PF15884.5 EPS32736.1 - 0.12 13.0 0.0 0.62 10.7 0.0 2.0 2 0 0 2 2 2 0 MICOS complex subunit MIC13, QIL1 Mito_carr PF00153.27 EPS32737.1 - 8.2e-68 224.4 5.9 6e-24 83.8 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 EPS32737.1 - 7.3e-22 77.6 3.8 3.4e-11 43.4 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EPS32737.1 - 2.6e-20 70.4 5.4 2.7e-06 26.5 0.0 3.9 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EPS32737.1 - 6.2e-16 56.9 6.4 7.9e-05 22.3 0.0 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 EPS32737.1 - 3.8e-15 54.6 7.1 0.00028 20.3 0.0 3.6 3 0 0 3 3 3 3 EF hand SPARC_Ca_bdg PF10591.9 EPS32737.1 - 4.2e-10 40.0 0.1 0.00032 21.0 0.0 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 EPS32737.1 - 3.7e-08 33.1 4.4 0.0042 16.9 0.2 4.0 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 EPS32737.1 - 0.045 13.7 2.4 4.2 7.4 0.3 2.8 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 EPS32737.1 - 0.29 11.0 0.9 20 5.1 0.0 3.1 3 0 0 3 3 3 0 EF hand Cyclin_N PF00134.23 EPS32738.1 - 7e-11 42.0 0.0 4.2e-10 39.4 0.0 2.1 2 1 0 2 2 2 1 Cyclin, N-terminal domain DUF5623 PF18536.1 EPS32738.1 - 0.076 13.3 0.2 0.13 12.5 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5623) Cyclin_C_2 PF16899.5 EPS32738.1 - 0.15 12.5 1.1 1.1 9.7 0.2 2.5 2 1 0 2 2 2 0 Cyclin C-terminal domain DUF4452 PF14618.6 EPS32739.1 - 5.7e-77 257.4 11.7 6.7e-77 257.1 11.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) SNARE PF05739.19 EPS32741.1 - 2.6e-08 33.7 0.6 5.4e-08 32.7 0.6 1.6 1 0 0 1 1 1 1 SNARE domain DUF4407 PF14362.6 EPS32741.1 - 0.0026 17.2 0.1 0.0077 15.6 0.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4407) Use1 PF09753.9 EPS32741.1 - 0.085 12.6 0.0 0.18 11.5 0.0 1.7 1 1 0 1 1 1 0 Membrane fusion protein Use1 XhlA PF10779.9 EPS32741.1 - 0.09 13.0 3.2 0.57 10.4 3.2 2.3 1 1 0 1 1 1 0 Haemolysin XhlA WXG100 PF06013.12 EPS32741.1 - 0.24 11.6 2.8 1.2 9.4 0.5 2.9 3 0 0 3 3 3 0 Proteins of 100 residues with WXG zf-TRAF PF02176.18 EPS32742.1 - 4.5e-14 52.9 27.8 1.6e-09 38.3 2.9 4.3 1 1 3 4 4 4 3 TRAF-type zinc finger zf-RING_UBOX PF13445.6 EPS32742.1 - 1.7e-08 34.4 12.0 5.4e-08 32.7 12.0 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-TRAF_2 PF15965.5 EPS32742.1 - 4.9e-07 30.1 23.1 4.9e-06 26.9 8.5 3.5 1 1 3 4 4 4 3 TRAF-like zinc-finger zf-C3HC4_4 PF15227.6 EPS32742.1 - 6.8e-06 26.1 13.3 6.8e-06 26.1 13.3 2.5 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-ACC PF17848.1 EPS32742.1 - 9e-06 25.7 10.2 0.002 18.1 0.1 4.9 4 0 0 4 4 4 1 Acetyl-coA carboxylase zinc finger domain zf-RING_2 PF13639.6 EPS32742.1 - 2e-05 24.8 13.6 2e-05 24.8 13.6 3.6 2 1 1 3 3 1 1 Ring finger domain zf-C3HC4 PF00097.25 EPS32742.1 - 2.8e-05 23.9 13.1 2.8e-05 23.9 13.1 3.8 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EPS32742.1 - 7.9e-05 22.5 12.5 7.9e-05 22.5 12.5 3.4 2 1 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EPS32742.1 - 0.00026 20.8 10.8 0.00026 20.8 10.8 3.9 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.16 EPS32742.1 - 0.17 11.8 17.6 0.25 11.2 1.8 2.8 2 1 1 3 3 3 0 Seven in absentia protein family Prok-RING_4 PF14447.6 EPS32742.1 - 0.21 11.5 13.9 41 4.1 14.4 3.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-Nse PF11789.8 EPS32742.1 - 1.3 8.9 15.2 0.11 12.4 8.0 2.8 3 0 0 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit zf-FPG_IleRS PF06827.14 EPS32742.1 - 9.1 6.2 12.9 0.34 10.8 0.3 4.1 4 0 0 4 4 4 0 Zinc finger found in FPG and IleRS KIND PF16474.5 EPS32744.1 - 0.018 14.9 2.3 0.028 14.3 2.3 1.3 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain Het-C PF07217.11 EPS32745.1 - 5.2e-275 913.3 0.0 7.1e-275 912.9 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Cation_efflux PF01545.21 EPS32746.1 - 3e-48 164.2 13.4 4.2e-48 163.7 13.4 1.2 1 0 0 1 1 1 1 Cation efflux family BPD_transp_2 PF02653.16 EPS32746.1 - 0.001 18.3 1.0 0.001 18.3 1.0 2.0 2 1 0 2 2 2 1 Branched-chain amino acid transport system / permease component PAP2_3 PF14378.6 EPS32746.1 - 0.26 11.0 3.2 5.4 6.7 0.1 2.4 2 0 0 2 2 2 0 PAP2 superfamily Abhydrolase_6 PF12697.7 EPS32747.1 - 1.8e-09 38.5 0.9 2.6e-09 38.0 0.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EPS32747.1 - 0.0064 16.2 0.0 0.0096 15.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ank_2 PF12796.7 EPS32748.1 - 1.9e-37 127.7 1.1 9.5e-15 55.0 0.0 8.7 8 1 1 9 9 9 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPS32748.1 - 1.7e-31 108.2 7.0 2.1e-08 34.5 0.0 10.3 9 2 2 11 11 11 8 Ankyrin repeats (many copies) Ank_5 PF13857.6 EPS32748.1 - 7.6e-27 93.0 2.4 0.00077 19.7 0.0 9.5 9 0 0 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPS32748.1 - 9.6e-22 74.7 14.6 0.0092 16.4 0.0 11.4 14 0 0 14 14 14 4 Ankyrin repeat Ank PF00023.30 EPS32748.1 - 5.1e-19 67.8 8.3 0.00023 21.5 0.0 9.3 10 0 0 10 10 10 5 Ankyrin repeat PhyH PF05721.13 EPS32749.1 - 2.3e-07 31.3 0.0 2.3e-06 28.0 0.0 2.2 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Zn_clus PF00172.18 EPS32752.1 - 1.9e-07 31.0 8.5 3.1e-07 30.4 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_23 PF13489.6 EPS32753.1 - 5.6e-21 75.1 0.0 8e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPS32753.1 - 7.1e-10 39.5 0.0 2e-09 38.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPS32753.1 - 4.7e-09 36.9 0.0 2.6e-08 34.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS32753.1 - 2.4e-07 31.3 0.0 5.6e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPS32753.1 - 3.4e-06 26.9 0.0 1.7e-05 24.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPS32753.1 - 0.0046 16.3 0.0 0.18 11.1 0.0 2.6 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.17 EPS32753.1 - 0.0097 15.4 0.0 0.024 14.1 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase DUF3730 PF12530.8 EPS32753.1 - 0.074 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3730) IBN_N PF03810.19 EPS32754.1 - 7e-11 41.9 0.6 1.2e-09 37.9 0.3 3.1 2 1 0 2 2 2 1 Importin-beta N-terminal domain RIX1 PF08167.12 EPS32754.1 - 0.0028 17.4 0.0 0.06 13.1 0.0 3.1 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis Xpo1 PF08389.12 EPS32754.1 - 0.0061 16.6 0.0 0.077 13.0 0.0 2.9 2 1 0 2 2 2 1 Exportin 1-like protein CAS_CSE1 PF03378.15 EPS32754.1 - 0.0072 14.9 0.0 0.032 12.7 0.0 2.0 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Adaptin_N PF01602.20 EPS32754.1 - 0.0093 14.6 0.0 0.046 12.3 0.0 2.1 2 0 0 2 2 2 1 Adaptin N terminal region RICTOR_N PF14664.6 EPS32754.1 - 0.052 12.5 0.4 0.13 11.2 0.2 1.7 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term UNC45-central PF11701.8 EPS32754.1 - 0.1 12.6 0.3 1.1 9.2 0.0 2.8 2 1 0 2 2 2 0 Myosin-binding striated muscle assembly central TAN PF11640.8 EPS32754.1 - 0.14 12.3 0.5 5.6 7.1 0.0 3.7 4 1 0 4 4 4 0 Telomere-length maintenance and DNA damage repair HORMA PF02301.18 EPS32755.1 - 1.2e-09 38.0 0.0 1.6e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 HORMA domain WD40 PF00400.32 EPS32757.1 - 5e-65 213.9 19.3 3e-10 40.5 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS32757.1 - 5e-21 74.8 0.3 0.00051 20.3 0.0 6.7 2 1 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EPS32757.1 - 1.3e-16 60.5 0.7 0.0042 16.1 0.0 6.2 1 1 5 6 6 6 5 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EPS32757.1 - 1e-06 28.5 4.5 1.7 8.7 0.1 6.5 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat Nup160 PF11715.8 EPS32757.1 - 2.1e-05 23.4 1.7 0.066 11.9 0.0 4.4 2 2 4 6 6 6 2 Nucleoporin Nup120/160 TruB_C PF09142.11 EPS32757.1 - 6.9e-05 22.5 0.0 1.5 8.7 0.0 4.0 3 1 1 4 4 4 2 tRNA Pseudouridine synthase II, C terminal DUF2415 PF10313.9 EPS32757.1 - 0.00013 21.8 0.9 4.2 7.4 0.0 5.0 6 0 0 6 6 6 1 Uncharacterised protein domain (DUF2415) Nucleoporin_N PF08801.11 EPS32757.1 - 0.0014 17.5 0.0 1.2 7.7 0.0 3.6 1 1 2 3 3 3 1 Nup133 N terminal like WD40_like PF17005.5 EPS32757.1 - 0.0029 17.0 0.0 0.46 9.8 0.0 2.4 2 0 0 2 2 2 1 WD40-like domain Coatomer_WDAD PF04053.14 EPS32757.1 - 0.0085 15.2 0.0 0.054 12.5 0.0 1.9 1 1 1 2 2 2 1 Coatomer WD associated region Nbas_N PF15492.6 EPS32757.1 - 0.017 14.5 3.4 5.4 6.3 0.0 4.2 1 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal PALB2_WD40 PF16756.5 EPS32757.1 - 0.018 14.0 0.1 0.46 9.3 0.0 2.4 1 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain potato_inhibit PF00280.18 EPS32757.1 - 0.06 14.0 0.2 5.8 7.7 0.0 3.7 4 1 1 5 5 5 0 Potato inhibitor I family SH3_4 PF06347.13 EPS32757.1 - 0.068 13.0 0.6 1.7 8.5 0.0 3.2 4 0 0 4 4 4 0 Bacterial SH3 domain Proteasome_A_N PF10584.9 EPS32757.1 - 0.072 12.8 10.6 5.5 6.8 0.0 5.6 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature Peptidase_S29 PF02907.15 EPS32757.1 - 0.085 12.6 0.4 0.49 10.1 0.1 2.2 2 0 0 2 2 2 0 Hepatitis C virus NS3 protease SH3_3 PF08239.11 EPS32757.1 - 0.13 12.6 0.6 3.3 8.0 0.0 3.0 3 1 0 3 3 3 0 Bacterial SH3 domain Acetyltransf_7 PF13508.7 EPS32758.1 - 1.7e-06 28.4 0.0 3.2e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EPS32758.1 - 6.2e-05 23.1 0.0 0.0002 21.4 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPS32758.1 - 0.00027 21.1 0.0 0.00066 19.9 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EPS32758.1 - 0.0005 20.0 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPS32758.1 - 0.0016 18.4 0.0 0.0041 17.0 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 EPS32758.1 - 0.017 14.6 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase Dcc1 PF09724.9 EPS32759.1 - 3.1e-20 72.7 0.0 3.7e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 Anp1 PF03452.14 EPS32760.1 - 2.1e-113 378.1 0.0 2.9e-113 377.7 0.0 1.2 1 0 0 1 1 1 1 Anp1 KR PF08659.10 EPS32761.1 - 2.2e-12 47.3 0.0 1.2e-11 44.9 0.0 2.0 2 0 0 2 2 2 1 KR domain adh_short PF00106.25 EPS32761.1 - 4.5e-09 36.0 0.0 6.9e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.21 EPS32761.1 - 0.0092 15.5 0.0 0.015 14.7 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EPS32761.1 - 0.022 13.9 0.0 0.036 13.2 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein bZIP_2 PF07716.15 EPS32762.1 - 3.5e-06 27.0 10.2 4.7e-06 26.6 10.2 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 EPS32762.1 - 6.1e-06 26.3 9.2 8.8e-06 25.7 9.2 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 EPS32762.1 - 0.00012 22.5 6.2 0.00018 21.9 6.2 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor Retinin_C PF04527.12 EPS32762.1 - 0.093 13.0 0.7 7.2 6.9 0.1 2.4 2 0 0 2 2 2 0 Drosophila Retinin like protein tRNA_bind PF01588.20 EPS32763.1 - 3.5e-21 75.1 0.0 4.4e-20 71.6 0.0 2.5 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_2 PF13410.6 EPS32763.1 - 2.9e-05 24.0 0.0 7.1e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EPS32763.1 - 5.5e-05 23.3 0.0 5.5e-05 23.3 0.0 2.8 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EPS32763.1 - 0.023 14.5 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EPS32763.1 - 0.39 10.9 0.0 0.39 10.9 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Asp PF00026.23 EPS32764.1 - 3.4e-63 214.0 3.2 4.2e-63 213.7 3.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EPS32764.1 - 1.4e-09 38.4 1.3 0.00043 20.6 0.3 2.9 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EPS32764.1 - 1.3e-05 25.8 1.0 0.11 13.1 0.5 2.8 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 EPS32764.1 - 0.0021 17.9 0.0 0.0053 16.5 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 EPS32764.1 - 0.12 13.0 0.5 32 5.2 0.0 3.1 2 1 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF3176 PF11374.8 EPS32766.1 - 5.2e-34 116.7 0.2 5.2e-34 116.7 0.2 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF3176) Sharpin_PH PF16764.5 EPS32766.1 - 0.15 11.8 0.0 0.63 9.8 0.0 1.9 2 0 0 2 2 2 0 Sharpin PH domain Excalibur PF05901.11 EPS32767.1 - 0.11 13.1 10.1 68 4.2 0.1 5.6 5 0 0 5 5 5 0 Excalibur calcium-binding domain YpzI PF14140.6 EPS32767.1 - 1 9.2 10.8 20 5.1 0.1 4.5 5 0 0 5 5 5 0 YpzI-like protein YmzC PF14157.6 EPS32767.1 - 7.6 6.7 6.7 92 3.2 0.1 4.0 3 0 0 3 3 3 0 YmzC-like protein ParA PF10609.9 EPS32768.1 - 1.6e-97 325.8 0.0 1.9e-97 325.6 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EPS32768.1 - 1.5e-09 38.0 0.0 2.8e-09 37.1 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EPS32768.1 - 1.2e-05 25.3 0.1 0.00011 22.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 EPS32768.1 - 2.2e-05 23.8 1.5 0.0011 18.2 0.3 2.7 1 1 1 3 3 3 1 Anion-transporting ATPase AAA_26 PF13500.6 EPS32768.1 - 0.0034 17.2 0.1 0.58 9.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain MipZ PF09140.11 EPS32768.1 - 0.0067 15.7 0.0 0.017 14.4 0.0 1.6 1 1 0 1 1 1 1 ATPase MipZ AAA_30 PF13604.6 EPS32768.1 - 0.0076 16.0 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EPS32768.1 - 0.0079 15.8 0.1 0.019 14.6 0.0 1.6 2 0 0 2 2 1 1 AAA domain RsgA_GTPase PF03193.16 EPS32768.1 - 0.0096 15.8 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase CLP1_P PF16575.5 EPS32768.1 - 0.021 14.6 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_16 PF13191.6 EPS32768.1 - 0.038 14.4 0.0 0.06 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Fer4_NifH PF00142.18 EPS32768.1 - 0.054 12.9 0.0 0.95 8.9 0.0 2.1 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family TsaE PF02367.17 EPS32768.1 - 0.072 13.1 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EPS32768.1 - 0.1 13.0 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase T2SSE PF00437.20 EPS32768.1 - 0.14 11.1 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Rad17 PF03215.15 EPS32768.1 - 0.17 11.8 0.0 0.3 11.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_5 PF07728.14 EPS32768.1 - 0.2 11.7 0.0 0.33 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 EPS32768.1 - 0.21 10.7 0.0 0.35 10.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Ras PF00071.22 EPS32768.1 - 0.22 11.1 0.0 0.4 10.3 0.0 1.4 1 0 0 1 1 1 0 Ras family PEMT PF04191.13 EPS32769.1 - 1.4e-60 202.3 7.1 6.8e-38 129.3 0.7 2.6 2 0 0 2 2 2 2 Phospholipid methyltransferase SKICH PF17751.1 EPS32769.1 - 0.00076 20.0 0.1 0.031 14.8 0.1 2.4 1 1 0 1 1 1 1 SKICH domain HECW_N PF16562.5 EPS32769.1 - 0.013 15.3 0.1 0.028 14.2 0.1 1.4 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 RNase_PH PF01138.21 EPS32770.1 - 5.1e-31 107.9 0.0 9.9e-31 107.0 0.0 1.5 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 HTH_AsnC-type PF13404.6 EPS32772.1 - 0.038 13.8 0.1 0.08 12.8 0.1 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain ProRS-C_1 PF09180.11 EPS32774.1 - 5.8e-23 80.9 0.8 1.4e-22 79.6 0.8 1.7 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 EPS32774.1 - 4.8e-18 65.7 0.0 7.7e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EPS32774.1 - 1.2e-12 47.8 0.7 5.2e-11 42.6 0.0 2.8 3 0 0 3 3 3 1 Anticodon binding domain Cpn60_TCP1 PF00118.24 EPS32775.1 - 8.8e-151 502.9 17.1 1e-150 502.7 17.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Dehyd-heme_bind PF09098.10 EPS32775.1 - 0.14 11.8 1.0 0.43 10.2 0.1 2.2 3 0 0 3 3 3 0 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding Phage_int_SAM_1 PF02899.17 EPS32775.1 - 0.15 12.4 0.1 1 9.7 0.0 2.4 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain WD40 PF00400.32 EPS32777.1 - 8.5e-16 58.1 1.6 0.00036 21.3 0.1 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS32777.1 - 4e-07 30.3 0.0 0.12 12.7 0.0 5.0 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Met_asp_mut_E PF06368.11 EPS32777.1 - 0.094 11.2 0.0 0.17 10.4 0.0 1.3 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) Hira PF07569.11 EPS32777.1 - 0.15 11.8 0.0 8.9 6.0 0.0 2.2 2 0 0 2 2 2 0 TUP1-like enhancer of split S1 PF00575.23 EPS32778.1 - 1.1e-72 240.4 26.3 9.9e-16 57.8 0.9 11.7 11 0 0 11 11 11 10 S1 RNA binding domain TPR_14 PF13428.6 EPS32778.1 - 5.3e-07 29.9 0.9 0.33 11.9 0.1 5.9 3 2 3 6 6 6 1 Tetratricopeptide repeat RNase_II_C_S1 PF18614.1 EPS32778.1 - 5.6e-06 26.2 1.0 15 5.6 0.0 6.8 7 0 0 7 7 7 1 RNase II-type exonuclease C-terminal S1 domain TPR_19 PF14559.6 EPS32778.1 - 6.8e-06 26.5 0.0 0.024 15.1 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat Suf PF05843.14 EPS32778.1 - 1.6e-05 25.0 7.3 0.11 12.4 0.0 4.0 2 1 2 4 4 4 3 Suppressor of forked protein (Suf) PPR PF01535.20 EPS32778.1 - 4.6e-05 23.4 0.1 0.52 10.7 0.1 3.1 2 0 0 2 2 2 2 PPR repeat TPR_15 PF13429.6 EPS32778.1 - 0.0006 19.1 0.4 0.38 9.9 0.0 2.7 2 1 1 3 3 3 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EPS32778.1 - 0.0015 18.5 0.1 0.0029 17.6 0.1 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 PPR_2 PF13041.6 EPS32778.1 - 0.0018 18.4 0.2 2.4 8.4 0.1 2.9 3 0 0 3 3 3 2 PPR repeat family GDPD_2 PF13653.6 EPS32779.1 - 0.00029 21.2 1.5 0.002 18.5 0.9 2.3 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family GDPD PF03009.17 EPS32779.1 - 0.12 12.0 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family UreD PF01774.17 EPS32780.1 - 3.1e-77 259.3 0.0 3.8e-77 259.0 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein STAG PF08514.11 EPS32781.1 - 4.9e-38 129.5 0.5 1.8e-37 127.7 0.5 2.1 1 0 0 1 1 1 1 STAG domain YL1 PF05764.13 EPS32781.1 - 0.0083 16.3 7.8 0.0083 16.3 7.8 5.8 4 1 0 4 4 4 2 YL1 nuclear protein HEAT_2 PF13646.6 EPS32781.1 - 0.06 13.7 0.0 0.36 11.3 0.0 2.4 1 0 0 1 1 1 0 HEAT repeats HEAT PF02985.22 EPS32781.1 - 0.13 12.6 0.2 2.5 8.6 0.1 2.9 2 0 0 2 2 2 0 HEAT repeat DHR10 PF18595.1 EPS32781.1 - 2.1 8.5 9.6 1.1 9.4 1.2 3.4 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain Arm PF00514.23 EPS32782.1 - 9.5e-94 304.9 13.7 8.9e-14 51.0 0.2 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 EPS32782.1 - 7e-25 87.3 1.4 1.7e-24 86.1 1.4 1.7 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 EPS32782.1 - 1.7e-23 81.9 3.6 3.6e-23 80.9 3.6 1.6 1 0 0 1 1 1 1 Atypical Arm repeat HEAT_EZ PF13513.6 EPS32782.1 - 4.4e-20 71.8 8.2 1.4e-08 35.1 0.0 6.5 6 1 1 7 7 7 3 HEAT-like repeat HEAT_2 PF13646.6 EPS32782.1 - 8.5e-19 67.7 0.2 2.8e-08 34.0 0.0 5.0 2 2 1 4 4 4 3 HEAT repeats HEAT PF02985.22 EPS32782.1 - 4.3e-17 60.8 1.1 1.7e-05 24.7 0.0 7.0 7 0 0 7 7 7 3 HEAT repeat Arm_2 PF04826.13 EPS32782.1 - 2.3e-08 33.8 0.0 0.0018 17.8 0.0 3.9 2 1 2 4 4 4 2 Armadillo-like V-ATPase_H_C PF11698.8 EPS32782.1 - 6.2e-05 23.1 0.0 1.8 8.7 0.0 4.4 3 2 2 5 5 5 2 V-ATPase subunit H Adaptin_N PF01602.20 EPS32782.1 - 0.0001 21.0 0.0 0.0099 14.5 0.0 2.4 1 1 1 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.7 EPS32782.1 - 0.011 15.8 0.0 8.2 6.4 0.0 3.2 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Glycos_trans_3N PF02885.17 EPS32782.1 - 0.029 14.2 0.0 5.4 6.9 0.0 3.4 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain Gcn1_N PF12074.8 EPS32782.1 - 0.15 11.3 0.0 11 5.2 0.0 2.3 2 0 0 2 2 2 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal Mo25 PF08569.11 EPS32782.1 - 0.23 10.8 0.0 0.37 10.1 0.0 1.3 1 0 0 1 1 1 0 Mo25-like HEAT_PBS PF03130.16 EPS32782.1 - 0.23 12.3 7.5 1.5 9.7 0.0 4.5 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat RICTOR_V PF14668.6 EPS32782.1 - 0.34 11.2 5.8 4.9 7.5 0.1 4.8 4 2 2 6 6 6 0 Rapamycin-insensitive companion of mTOR, domain 5 POT1PC PF16686.5 EPS32783.1 - 6.2e-37 126.9 0.0 5.4e-35 120.6 0.0 2.2 2 0 0 2 2 2 2 ssDNA-binding domain of telomere protection protein POT1 PF02765.17 EPS32783.1 - 3.2e-18 65.9 0.0 9e-18 64.5 0.0 1.7 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 zf-CCCH_2 PF14608.6 EPS32784.1 - 0.01 16.3 0.9 0.01 16.3 0.9 3.2 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger TRAP_alpha PF03896.16 EPS32785.1 - 1.8e-16 60.2 0.0 2.3e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit PepSY_TM PF03929.16 EPS32785.1 - 0.17 11.5 0.3 11 5.6 0.0 2.4 2 1 1 3 3 3 0 PepSY-associated TM region zf-C2HE PF16278.5 EPS32786.1 - 7.4e-19 68.0 0.1 2.6e-18 66.2 0.0 2.0 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger DcpS_C PF11969.8 EPS32786.1 - 1.3e-18 67.5 2.5 1.2e-17 64.4 2.5 2.1 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 EPS32786.1 - 1.5e-15 57.7 1.8 5.6e-15 55.9 1.8 1.9 1 1 0 1 1 1 1 HIT domain HA2 PF04408.23 EPS32787.1 - 2.5e-17 63.1 0.4 2.1e-16 60.2 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EPS32787.1 - 1.3e-15 57.5 0.0 2.6e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EPS32787.1 - 9.6e-13 48.5 0.0 2.7e-12 47.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RWD PF05773.22 EPS32787.1 - 5.6e-12 46.0 0.0 1.8e-11 44.4 0.0 1.9 1 0 0 1 1 1 1 RWD domain DEAD PF00270.29 EPS32787.1 - 1.7e-09 37.7 0.0 3e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EPS32787.1 - 0.0046 17.2 0.3 5 7.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 EPS32787.1 - 0.011 14.9 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DND1_DSRM PF14709.7 EPS32787.1 - 0.016 15.4 0.1 0.057 13.7 0.1 2.0 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 UBA PF00627.31 EPS32787.1 - 0.018 14.9 0.0 5.6 7.0 0.0 2.7 2 0 0 2 2 2 0 UBA/TS-N domain PhoH PF02562.16 EPS32787.1 - 0.026 14.0 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_29 PF13555.6 EPS32787.1 - 0.028 14.2 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATPase PF06745.13 EPS32787.1 - 0.054 12.8 0.1 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 KaiC Rap1_C PF11626.8 EPS32787.1 - 0.054 13.6 0.1 0.43 10.7 0.0 2.6 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain dsRBD2 PF17842.1 EPS32787.1 - 0.078 13.2 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 Double-stranded RNA binding domain 2 AAA_23 PF13476.6 EPS32787.1 - 2.9 8.4 4.7 0.81 10.2 0.6 2.1 2 1 0 2 2 2 0 AAA domain Cyclin_N PF00134.23 EPS32788.1 - 2.2e-40 137.3 0.0 3.7e-40 136.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EPS32788.1 - 1.2e-33 115.7 0.1 2.8e-33 114.5 0.1 1.7 2 0 0 2 2 2 1 Cyclin, C-terminal domain Zn_clus PF00172.18 EPS32790.1 - 0.00044 20.3 10.9 0.00085 19.4 10.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.10 EPS32790.1 - 0.092 12.2 0.1 0.32 10.5 0.1 2.0 1 0 0 1 1 1 0 Histone chaperone domain CHZ RNA_pol_Rpc4 PF05132.14 EPS32792.1 - 6.3e-33 114.3 0.1 6.3e-33 114.3 0.1 4.3 2 2 3 5 5 5 1 RNA polymerase III RPC4 DUF1418 PF07214.12 EPS32795.1 - 0.019 14.8 0.0 0.023 14.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) CRCB PF02537.15 EPS32796.1 - 3.5e-37 126.6 15.6 6e-22 77.8 7.7 2.5 2 1 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) UPRTase PF14681.6 EPS32797.1 - 1.8e-72 243.2 0.0 2.1e-72 242.9 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EPS32797.1 - 2.4e-05 23.9 0.2 5e-05 22.9 0.2 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain NAD_binding_10 PF13460.6 EPS32797.1 - 0.07 13.0 0.1 0.1 12.5 0.1 1.2 1 0 0 1 1 1 0 NAD(P)H-binding Fungal_trans PF04082.18 EPS32798.1 - 7.8e-22 77.6 3.1 1.3e-21 76.9 3.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 EPS32798.1 - 8.6e-07 29.1 14.9 7.4e-05 23.0 5.5 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 EPS32798.1 - 0.0011 19.4 14.3 0.038 14.4 5.3 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPS32798.1 - 0.002 18.8 12.6 0.26 12.2 4.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 EPS32798.1 - 0.048 14.3 0.6 1.4 9.6 0.3 2.6 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats Zn-ribbon_8 PF09723.10 EPS32798.1 - 1.5 9.0 3.7 5.7 7.1 3.7 2.0 1 0 0 1 1 1 0 Zinc ribbon domain zf-C2H2_jaz PF12171.8 EPS32798.1 - 2.1 8.7 6.6 1.3 9.4 3.7 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding RasGEF PF00617.19 EPS32802.1 - 9e-59 198.6 0.0 1.6e-58 197.8 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EPS32802.1 - 2.1e-30 105.1 0.5 4.1e-30 104.1 0.5 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.28 EPS32802.1 - 2.5e-15 55.8 0.1 2.5e-15 55.8 0.1 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EPS32802.1 - 2.5e-13 49.7 0.1 7.8e-13 48.1 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EPS32802.1 - 3.9e-11 42.5 0.0 9e-11 41.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.26 EPS32802.1 - 0.0068 16.5 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 WW domain JAB PF01398.21 EPS32803.1 - 3e-30 104.6 0.0 6.4e-30 103.6 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 EPS32803.1 - 4.6e-20 72.3 0.1 9.6e-20 71.3 0.1 1.6 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 EPS32803.1 - 0.00035 20.3 0.0 0.00059 19.6 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain SRP1_TIP1 PF00660.17 EPS32803.1 - 0.039 14.0 0.1 0.099 12.7 0.1 1.7 1 0 0 1 1 1 0 Seripauperin and TIP1 family MAP65_ASE1 PF03999.12 EPS32804.1 - 4.6e-69 233.7 33.2 1.2e-68 232.3 33.2 1.7 1 1 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Pou PF00157.17 EPS32804.1 - 0.044 13.8 0.1 0.14 12.1 0.1 1.9 1 0 0 1 1 1 0 Pou domain - N-terminal to homeobox domain Abhydrolase_6 PF12697.7 EPS32805.1 - 1.1e-06 29.4 0.0 2.5e-06 28.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPS32805.1 - 0.00011 21.6 0.0 0.025 13.8 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EPS32805.1 - 0.00042 20.0 0.1 0.95 9.1 0.1 2.4 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_8 PF06259.12 EPS32805.1 - 0.082 12.5 1.2 7.9 6.1 0.3 2.2 1 1 1 2 2 2 0 Alpha/beta hydrolase DUF1749 PF08538.10 EPS32805.1 - 0.1 11.6 0.0 0.45 9.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) DnaJ_C PF01556.18 EPS32806.1 - 7.8e-37 126.6 0.2 1.1e-36 126.1 0.2 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EPS32806.1 - 4.6e-23 81.1 1.8 9.1e-23 80.2 1.8 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EPS32806.1 - 1.1e-13 51.3 17.9 2e-13 50.5 17.9 1.4 1 0 0 1 1 1 1 DnaJ central domain CxC3 PF18804.1 EPS32806.1 - 0.13 12.1 1.6 0.26 11.2 1.3 1.5 1 1 0 1 1 1 0 CxC3 like cysteine cluster associated with KDZ transposases Anti-TRAP PF15777.5 EPS32806.1 - 0.77 9.8 14.2 1.8 8.6 2.9 2.5 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Forkhead_N PF08430.12 EPS32806.1 - 0.87 10.2 7.0 1.5 9.4 7.0 1.3 1 0 0 1 1 1 0 Forkhead N-terminal region zf-RING_10 PF16685.5 EPS32806.1 - 3.1 8.0 9.8 2.8 8.1 1.1 2.2 1 1 1 2 2 2 0 zinc RING finger of MSL2 tRNA-synt_1c PF00749.21 EPS32807.1 - 4.8e-91 304.9 0.0 6e-91 304.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Fmp27 PF10344.9 EPS32808.1 - 1.4e-238 794.4 0.0 1.4e-238 794.4 0.0 2.8 5 0 0 5 5 5 1 Mitochondrial protein from FMP27 Apt1 PF10351.9 EPS32808.1 - 2.3e-194 646.7 0.1 2.3e-194 646.7 0.1 4.8 5 0 0 5 5 5 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.9 EPS32808.1 - 8.4e-175 582.2 8.4 1.8e-174 581.2 8.4 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 EPS32808.1 - 6.7e-56 188.5 0.4 1.5e-55 187.4 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_GFWDK PF10347.9 EPS32808.1 - 1.2e-54 184.7 0.3 4.2e-54 182.9 0.0 2.2 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Fmp27_SW PF10305.9 EPS32808.1 - 8e-32 110.0 0.0 9.4e-30 103.4 0.0 3.5 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Orthopox_A36R PF05950.11 EPS32808.1 - 0.14 12.3 0.5 0.72 10.0 0.0 2.4 2 0 0 2 2 2 0 Orthopoxvirus A36R protein CdvA PF18822.1 EPS32808.1 - 9.4 6.1 10.5 6.6 6.6 1.2 3.0 3 0 0 3 3 3 0 CdvA-like coiled-coil domain Osmo_CC PF08946.10 EPS32809.1 - 0.014 15.7 0.1 0.019 15.2 0.1 1.2 1 0 0 1 1 1 0 Osmosensory transporter coiled coil DUF4311 PF14188.6 EPS32809.1 - 0.5 10.1 2.4 1.7 8.4 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4311) RRM_1 PF00076.22 EPS32810.1 - 4.4e-14 52.0 0.0 7.9e-14 51.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ferlin_C PF16165.5 EPS32810.1 - 0.49 10.3 4.1 0.85 9.6 4.1 1.3 1 0 0 1 1 1 0 Ferlin C-terminus HlyD_D4 PF16572.5 EPS32811.1 - 0.18 11.7 1.2 0.38 10.7 1.2 1.5 1 0 0 1 1 1 0 Long alpha hairpin domain of cation efflux system protein, CusB Sec2p PF06428.11 EPS32812.1 - 7.3e-10 38.7 14.6 1e-09 38.2 10.2 2.2 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p Jnk-SapK_ap_N PF09744.9 EPS32812.1 - 0.001 19.3 17.7 0.1 12.8 10.8 2.2 2 0 0 2 2 2 2 JNK_SAPK-associated protein-1 CMV_1a PF12467.8 EPS32812.1 - 0.031 14.6 0.4 0.031 14.6 0.4 2.4 2 1 1 3 3 3 0 Cucumber mosaic virus 1a protein family Rtf2 PF04641.12 EPS32812.1 - 0.038 13.4 0.1 0.038 13.4 0.1 2.0 2 0 0 2 2 2 0 Rtf2 RING-finger Exonuc_VII_L PF02601.15 EPS32812.1 - 0.057 13.0 15.2 0.012 15.1 4.3 2.0 1 1 1 2 2 2 0 Exonuclease VII, large subunit DUF2746 PF10874.8 EPS32812.1 - 0.066 13.6 0.0 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) FAM76 PF16046.5 EPS32812.1 - 0.22 10.9 7.6 0.25 10.6 6.8 1.4 1 1 0 1 1 1 0 FAM76 protein Uds1 PF15456.6 EPS32812.1 - 0.26 11.5 21.3 0.23 11.7 2.7 2.3 2 0 0 2 2 2 0 Up-regulated During Septation APG6_N PF17675.1 EPS32812.1 - 0.36 11.4 15.5 2.1 8.9 0.1 2.4 2 1 0 2 2 2 0 Apg6 coiled-coil region ECSIT PF06239.11 EPS32812.1 - 0.4 9.8 1.3 0.68 9.0 1.3 1.3 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway Herpes_UL6 PF01763.16 EPS32812.1 - 0.8 8.1 7.9 0.045 12.3 0.4 1.9 2 0 0 2 2 2 0 Herpesvirus UL6 like HSBP1 PF06825.12 EPS32812.1 - 0.84 9.5 2.9 8.6 6.3 0.0 2.8 3 0 0 3 3 3 0 Heat shock factor binding protein 1 DUF2072 PF09845.9 EPS32812.1 - 1.1 9.5 4.4 4.3 7.6 0.0 2.2 2 0 0 2 2 2 0 Zn-ribbon containing protein SlyX PF04102.12 EPS32812.1 - 1.4 9.6 13.6 0.98 10.1 0.2 3.5 2 1 1 3 3 3 0 SlyX SDP_N PF12278.8 EPS32812.1 - 1.5 8.9 10.2 0.17 12.0 4.1 2.0 2 0 0 2 2 2 0 Sex determination protein N terminal Vac_Fusion PF02346.16 EPS32812.1 - 1.6 8.4 5.3 2.5 7.8 1.8 2.3 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 ADIP PF11559.8 EPS32812.1 - 1.6 8.8 16.3 1.1 9.4 0.2 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Atg14 PF10186.9 EPS32812.1 - 2 7.4 19.8 0.06 12.4 2.3 2.1 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 YlqD PF11068.8 EPS32812.1 - 2.4 8.5 10.6 4.8 7.6 8.3 2.0 2 0 0 2 2 2 0 YlqD protein FlaC_arch PF05377.11 EPS32812.1 - 5.9 7.4 7.4 14 6.2 0.1 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) TFIIA PF03153.13 EPS32812.1 - 8.9 6.2 10.6 12 5.8 10.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BBP1_C PF15272.6 EPS32812.1 - 9.2 6.0 12.0 8.4 6.2 1.0 2.2 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal TMF_DNA_bd PF12329.8 EPS32812.1 - 9.3 6.3 15.1 1.9 8.6 0.3 2.8 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding GFO_IDH_MocA PF01408.22 EPS32813.1 - 6.9e-13 49.5 0.0 1.2e-12 48.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EPS32813.1 - 7.5e-05 22.7 0.0 0.00012 22.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Ribosomal_L32e PF01655.18 EPS32814.1 - 6.3e-50 168.1 0.8 6.3e-50 168.1 0.8 1.4 2 0 0 2 2 2 1 Ribosomal protein L32 PseudoU_synth_2 PF00849.22 EPS32815.1 - 3.4e-26 92.2 0.0 5.2e-26 91.6 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase GFA PF04828.14 EPS32815.1 - 0.042 14.2 0.0 0.087 13.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme 4HBT PF03061.22 EPS32816.1 - 7.3e-15 55.1 0.0 1.1e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 EPS32816.1 - 0.00022 21.7 0.0 0.00029 21.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.17 EPS32816.1 - 0.0011 18.4 0.1 0.0017 17.7 0.1 1.3 1 0 0 1 1 1 1 Acyl-ACP thioesterase B-block_TFIIIC PF04182.12 EPS32819.1 - 1.6e-19 69.9 0.0 4.1e-19 68.5 0.0 1.8 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC MarR PF01047.22 EPS32819.1 - 0.007 16.3 0.0 0.027 14.4 0.0 2.1 1 0 0 1 1 1 1 MarR family HTH_36 PF13730.6 EPS32819.1 - 0.01 15.8 0.0 0.39 10.7 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain MarR_2 PF12802.7 EPS32819.1 - 0.014 15.3 0.0 0.1 12.5 0.0 2.6 2 0 0 2 2 2 0 MarR family UQ_con PF00179.26 EPS32820.1 - 3.4e-19 68.9 0.0 6.2e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EPS32820.1 - 0.02 15.2 0.0 0.037 14.3 0.0 1.4 1 0 0 1 1 1 0 RWD domain SOG2 PF10428.9 EPS32820.1 - 4.6 6.3 10.9 6.1 5.9 10.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DHHC PF01529.20 EPS32821.1 - 1e-36 126.0 8.4 1.7e-36 125.2 8.4 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase Rhomboid PF01694.22 EPS32822.1 - 1.8e-32 112.4 8.8 1.8e-32 112.4 8.8 1.5 2 0 0 2 2 2 1 Rhomboid family SPT_ssu-like PF11779.8 EPS32823.1 - 1.3e-15 56.7 3.4 1.9e-15 56.2 3.4 1.3 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like Kinetochor_Ybp2 PF08568.10 EPS32825.1 - 1.1e-147 493.3 0.1 1.3e-147 493.0 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin PLDc_2 PF13091.6 EPS32827.1 - 2.4e-15 56.6 0.0 5.5e-06 26.3 0.0 3.7 3 1 0 3 3 3 3 PLD-like domain PLDc PF00614.22 EPS32827.1 - 1.3e-12 47.4 1.0 2.3e-05 24.4 0.3 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Cyanate_lyase PF02560.14 EPS32828.1 - 2.5e-32 110.5 0.0 3.6e-32 110.0 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_3 PF01381.22 EPS32828.1 - 0.0091 16.0 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 EPS32828.1 - 0.039 14.3 0.0 0.057 13.8 0.0 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_19 PF12844.7 EPS32828.1 - 0.071 13.1 0.1 0.23 11.5 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain Carb_kinase PF01256.17 EPS32829.1 - 0.054 13.0 0.0 0.054 13.0 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate kinase DNA_pol_B PF00136.21 EPS32832.1 - 1.1e-148 495.8 2.0 1.5e-148 495.3 2.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EPS32832.1 - 3.5e-78 263.1 0.0 5.6e-78 262.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EPS32832.1 - 1.6e-18 66.9 5.9 4.1e-18 65.6 5.9 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.6 EPS32832.1 - 0.0036 17.3 0.4 0.027 14.5 0.4 2.4 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_2 PF03175.13 EPS32832.1 - 0.017 14.0 0.5 0.17 10.7 0.0 2.2 2 0 0 2 2 2 0 DNA polymerase type B, organellar and viral DUF2614 PF11023.8 EPS32832.1 - 0.14 12.3 0.1 0.28 11.3 0.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon containing domain C1_1 PF00130.22 EPS32832.1 - 0.14 12.0 9.6 0.04 13.8 1.0 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase PF00069.25 EPS32833.1 - 9.2e-37 126.8 0.0 7.4e-22 78.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EPS32833.1 - 5e-18 65.3 0.0 4.4e-15 55.7 0.0 2.9 2 1 0 2 2 2 2 Protein tyrosine kinase FTA2 PF13095.6 EPS32833.1 - 0.011 15.4 0.0 0.46 10.1 0.0 2.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Acyl-CoA_dh_1 PF00441.24 EPS32834.1 - 1.2e-30 106.8 0.4 1.6e-30 106.3 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EPS32834.1 - 2.6e-27 95.7 0.0 6.4e-27 94.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EPS32834.1 - 1.2e-23 83.1 0.0 2.2e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Syja_N PF02383.18 EPS32835.1 - 1.2e-78 264.7 0.1 1.8e-78 264.1 0.1 1.3 1 0 0 1 1 1 1 SacI homology domain Tti2 PF10521.9 EPS32836.1 - 7.5e-92 307.8 1.3 1.1e-91 307.3 1.3 1.3 1 0 0 1 1 1 1 Tti2 family PolyA_pol PF01743.20 EPS32837.1 - 1e-22 80.9 1.5 3.2e-22 79.3 1.5 1.8 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 EPS32837.1 - 2.1e-09 37.0 0.0 5.7e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 EPS32837.1 - 0.016 15.2 0.1 0.04 13.9 0.0 1.7 2 0 0 2 2 2 0 tRNA nucleotidyltransferase domain 2 putative TRAPPC-Trs85 PF12739.7 EPS32838.1 - 2e-112 376.1 0.0 2.8e-112 375.7 0.0 1.1 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Snf7 PF03357.21 EPS32839.1 - 4.9e-17 62.0 14.0 4.9e-17 62.0 14.0 1.9 1 1 1 2 2 2 1 Snf7 MbeD_MobD PF04899.12 EPS32839.1 - 0.24 11.6 4.8 0.62 10.2 0.0 3.3 3 0 0 3 3 3 0 MbeD/MobD like HHH_2 PF12826.7 EPS32839.1 - 1.4 9.1 4.0 25 5.1 0.1 3.3 2 1 1 3 3 3 0 Helix-hairpin-helix motif BUD22 PF09073.10 EPS32839.1 - 1.8 7.8 15.8 2.7 7.2 15.8 1.2 1 0 0 1 1 1 0 BUD22 LXG PF04740.12 EPS32839.1 - 2.3 7.9 19.1 0.093 12.4 4.8 2.5 1 1 1 2 2 2 0 LXG domain of WXG superfamily Baculo_PEP_C PF04513.12 EPS32839.1 - 3.9 7.5 14.7 2.7 8.0 5.8 3.1 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus SKA2 PF16740.5 EPS32839.1 - 4.4 7.1 14.1 1.4 8.8 1.5 3.5 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 YlqD PF11068.8 EPS32839.1 - 6.1 7.2 17.8 0.44 10.9 4.6 2.6 2 0 0 2 2 2 0 YlqD protein DUF948 PF06103.11 EPS32839.1 - 7 7.0 13.0 52 4.2 8.4 3.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 EPS32839.1 - 9.2 6.8 11.4 32 5.1 4.4 3.8 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein zf-C3HC4_2 PF13923.6 EPS32840.1 - 1.5e-10 40.8 12.5 1.5e-10 40.8 12.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPS32840.1 - 2.9e-07 30.3 12.8 2.9e-07 30.3 12.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EPS32840.1 - 3.5e-07 30.0 13.6 9.8e-07 28.5 9.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EPS32840.1 - 1.6e-06 27.9 16.9 3.6e-06 26.8 12.9 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 EPS32840.1 - 1.7e-06 27.8 6.1 3.7e-06 26.7 6.1 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.6 EPS32840.1 - 3.4e-06 27.0 11.5 3.4e-06 27.0 11.5 2.3 2 0 0 2 2 2 1 RING-type zinc-finger SAP PF02037.27 EPS32840.1 - 1.8e-05 24.3 0.0 3.6e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 SAP domain zf-RING_2 PF13639.6 EPS32840.1 - 2.8e-05 24.3 18.3 4.5e-05 23.7 13.6 2.3 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 EPS32840.1 - 6e-05 22.8 12.6 0.032 14.1 10.5 2.3 2 0 0 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EPS32840.1 - 0.00012 22.2 15.6 0.00013 22.1 12.7 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 EPS32840.1 - 0.0003 21.0 7.0 0.0003 21.0 7.0 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain Mob_synth_C PF06463.13 EPS32840.1 - 0.00086 19.2 3.2 0.0019 18.1 3.2 1.6 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C zf-RING_10 PF16685.5 EPS32840.1 - 0.0044 17.1 5.4 0.0044 17.1 5.4 1.8 2 0 0 2 2 1 1 zinc RING finger of MSL2 V-ATPase_G_2 PF16999.5 EPS32840.1 - 0.13 12.7 2.4 1.3 9.5 2.2 2.2 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit zf-RING_4 PF14570.6 EPS32840.1 - 0.13 12.1 12.3 0.34 10.7 10.3 2.5 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Sgf11 PF08209.11 EPS32840.1 - 0.18 11.4 0.1 0.18 11.4 0.1 2.9 3 1 1 4 4 4 0 Sgf11 (transcriptional regulation protein) zf-ANAPC11 PF12861.7 EPS32840.1 - 1.4 9.0 7.2 0.16 12.0 2.8 1.7 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zinc-ribbons_6 PF07191.12 EPS32840.1 - 2.4 8.2 10.1 20 5.3 7.2 2.5 2 0 0 2 2 2 0 zinc-ribbons CDC27 PF09507.10 EPS32841.1 - 2.4e-103 346.8 22.3 2.9e-103 346.5 22.3 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Glyco_hydro_125 PF06824.11 EPS32842.1 - 4.5e-179 595.7 0.5 5.2e-179 595.5 0.5 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) PXA PF02194.15 EPS32842.1 - 0.15 12.0 0.4 0.29 11.1 0.4 1.6 1 1 0 1 1 1 0 PXA domain Pex2_Pex12 PF04757.14 EPS32843.1 - 5.3e-55 186.4 4.6 7e-55 186.1 4.6 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.6 EPS32843.1 - 1.3e-05 25.2 3.1 2.4e-05 24.4 3.1 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EPS32843.1 - 0.0019 18.0 3.8 0.0024 17.6 2.6 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EPS32843.1 - 0.002 18.0 2.1 0.0035 17.2 2.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPS32843.1 - 0.0044 16.8 2.5 0.0079 16.0 2.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EPS32843.1 - 0.006 16.9 2.9 0.012 16.0 2.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EPS32843.1 - 0.01 15.8 3.3 0.01 15.8 3.3 1.7 2 0 0 2 2 2 0 RING-type zinc-finger PRP38_assoc PF12871.7 EPS32843.1 - 4.4 8.0 9.5 1.1 9.9 2.4 2.3 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term RsfS PF02410.15 EPS32844.1 - 6.7e-13 48.9 0.0 2e-12 47.4 0.0 1.8 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation NMD3 PF04981.13 EPS32845.1 - 2.3e-81 272.8 8.0 3.8e-81 272.1 8.0 1.3 1 0 0 1 1 1 1 NMD3 family zf_Rg PF17915.1 EPS32845.1 - 0.03 13.7 0.5 0.067 12.6 0.5 1.6 1 0 0 1 1 1 0 Reverse gyrase zinc finger HypA PF01155.19 EPS32845.1 - 1.3 9.0 10.0 3.1 7.9 0.1 2.9 2 1 1 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 EPS32845.1 - 3.1 7.9 9.3 27 4.9 6.9 2.6 2 1 0 2 2 2 0 Double zinc ribbon FYVE PF01363.21 EPS32845.1 - 7.4 6.8 9.3 12 6.1 5.0 2.7 2 0 0 2 2 2 0 FYVE zinc finger RRM_1 PF00076.22 EPS32846.1 - 0.0065 16.3 0.0 0.08 12.8 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAM60A PF15396.6 EPS32846.1 - 6 6.8 12.9 1.8 8.5 5.6 2.5 2 0 0 2 2 2 0 Protein Family FAM60A Mito_carr PF00153.27 EPS32847.1 - 1.7e-62 207.4 3.7 5e-21 74.4 0.1 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EPS32847.1 - 0.057 12.6 0.0 2 7.5 0.0 2.4 2 0 0 2 2 2 0 Gammaproteobacterial serine protease WAC_Acf1_DNA_bd PF10537.9 EPS32848.1 - 6.9e-40 135.6 0.2 6.9e-40 135.6 0.2 2.2 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 EPS32848.1 - 1.3e-22 80.1 0.3 1.3e-22 80.1 0.3 3.3 3 1 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 EPS32848.1 - 2e-17 63.2 2.1 4.2e-17 62.2 2.1 1.6 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 EPS32848.1 - 3.9e-09 35.8 0.1 1.9e-08 33.6 0.1 2.3 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Alg6_Alg8 PF03155.15 EPS32849.1 - 1.9e-173 577.9 32.2 2.3e-173 577.7 32.2 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Corona_5a PF06336.11 EPS32850.1 - 0.0064 16.5 0.2 0.0099 15.8 0.2 1.3 1 0 0 1 1 1 1 Coronavirus 5a protein Lectin_leg-like PF03388.13 EPS32851.1 - 7.6e-27 94.1 0.0 1.2e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family Macoilin PF09726.9 EPS32851.1 - 0.027 13.1 7.6 0.036 12.7 7.6 1.1 1 0 0 1 1 1 0 Macoilin family FAM196 PF15265.6 EPS32851.1 - 0.11 11.9 11.3 0.16 11.4 11.3 1.1 1 0 0 1 1 1 0 FAM196 family TFIIA PF03153.13 EPS32851.1 - 0.19 11.7 17.8 0.26 11.2 17.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SURF6 PF04935.12 EPS32851.1 - 0.4 10.5 9.5 0.58 9.9 9.5 1.1 1 0 0 1 1 1 0 Surfeit locus protein 6 Neur_chan_memb PF02932.16 EPS32851.1 - 0.49 10.4 6.5 0.1 12.6 2.4 1.8 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region MPS2 PF17060.5 EPS32851.1 - 3.3 6.9 10.2 4 6.6 6.9 2.0 1 1 1 2 2 2 0 Monopolar spindle protein 2 EMP24_GP25L PF01105.24 EPS32851.1 - 4 7.4 6.0 91 2.9 5.8 2.4 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Spt20 PF12090.8 EPS32851.1 - 5.2 6.6 20.0 8.3 6.0 20.0 1.3 1 0 0 1 1 1 0 Spt20 family Pkinase PF00069.25 EPS32852.1 - 1.1e-14 54.5 0.0 7.9e-14 51.7 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS32852.1 - 1.4e-05 24.6 0.0 0.00034 20.0 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase PHD PF00628.29 EPS32853.1 - 7.4e-20 70.6 18.2 1e-09 38.1 9.6 2.6 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.6 EPS32853.1 - 5.7e-05 22.6 10.6 0.0031 17.0 1.7 3.6 3 0 0 3 3 3 2 PHD-finger zf-PHD-like PF15446.6 EPS32853.1 - 0.0033 17.1 6.6 0.26 10.9 1.3 2.7 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain zf-HC5HC2H PF13771.6 EPS32853.1 - 0.0066 16.7 9.4 0.055 13.7 3.8 2.5 2 0 0 2 2 2 2 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 EPS32853.1 - 0.05 13.8 4.2 0.18 12.0 0.7 2.4 2 0 0 2 2 2 0 PHD-zinc-finger like domain C1_1 PF00130.22 EPS32853.1 - 0.074 12.9 11.7 0.16 11.9 0.7 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) FoP_duplication PF13865.6 EPS32853.1 - 7.2 7.2 7.0 20 5.8 7.0 1.7 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Peptidase_M24 PF00557.24 EPS32854.1 - 2.7e-07 30.5 0.1 6.6e-07 29.2 0.1 1.7 1 1 0 1 1 1 1 Metallopeptidase family M24 Exo_endo_phos PF03372.23 EPS32856.1 - 3.8e-07 29.9 0.1 1.1e-06 28.3 0.1 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Glyco_transf_29 PF00777.18 EPS32857.1 - 0.099 12.0 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 29 (sialyltransferase) SNF5 PF04855.12 EPS32858.1 - 4.1e-64 216.6 0.2 5.1e-63 213.0 0.2 2.2 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Cecropin PF00272.19 EPS32858.1 - 0.14 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Cecropin family HEAT_2 PF13646.6 EPS32859.1 - 3.6e-06 27.3 9.7 1.1e-05 25.7 0.5 4.8 4 1 1 5 5 4 2 HEAT repeats Cnd1 PF12717.7 EPS32859.1 - 9.6e-06 25.7 0.4 0.001 19.1 0.0 4.2 3 2 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EPS32859.1 - 1.4e-05 24.9 8.3 0.057 13.7 0.0 5.9 5 0 0 5 5 5 1 HEAT repeat NLRC4_HD PF17889.1 EPS32859.1 - 0.0095 16.3 0.8 6.4 7.2 0.1 4.0 3 0 0 3 3 3 1 NLRC4 helical domain HEAT_EZ PF13513.6 EPS32859.1 - 0.017 15.6 3.8 0.23 12.0 0.0 4.3 4 0 0 4 4 4 0 HEAT-like repeat CLASP_N PF12348.8 EPS32859.1 - 0.021 14.4 0.1 3.1 7.3 0.0 2.9 1 1 1 2 2 2 0 CLASP N terminal Gcn1_N PF12074.8 EPS32859.1 - 0.022 14.0 1.4 2.1 7.6 0.0 3.7 3 1 0 3 3 3 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal RIX1 PF08167.12 EPS32859.1 - 0.034 13.9 0.2 7.6 6.2 0.0 3.4 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis Nipped-B_C PF12830.7 EPS32859.1 - 0.21 11.5 1.1 3 7.8 0.1 2.9 3 0 0 3 3 3 0 Sister chromatid cohesion C-terminus Nop14 PF04147.12 EPS32859.1 - 1.1 7.3 35.7 1.5 6.9 30.7 2.6 2 0 0 2 2 2 0 Nop14-like family NOA36 PF06524.12 EPS32859.1 - 1.9 7.7 25.4 6.6 6.0 25.4 1.9 1 0 0 1 1 1 0 NOA36 protein MFS_1 PF07690.16 EPS32860.1 - 1.3e-38 132.9 43.1 1.3e-38 132.9 43.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 EPS32860.1 - 0.28 9.4 13.5 0.011 14.0 5.6 2.5 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family AAA PF00004.29 EPS32861.1 - 8.7e-98 323.9 0.0 1.4e-47 161.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EPS32861.1 - 2.9e-22 78.2 3.7 1.2e-12 47.4 0.3 2.8 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 EPS32861.1 - 8e-19 67.6 1.2 2e-18 66.3 0.5 2.1 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.14 EPS32861.1 - 5.6e-14 52.6 0.0 1.5e-07 31.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EPS32861.1 - 1e-13 51.3 0.0 1.2e-05 25.1 0.0 3.3 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EPS32861.1 - 2e-12 47.5 0.0 1.3e-05 25.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EPS32861.1 - 2.5e-12 47.5 0.0 0.00013 22.4 0.0 4.4 2 2 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 EPS32861.1 - 1.2e-10 41.6 0.6 2e-05 24.6 0.1 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EPS32861.1 - 5.8e-09 35.6 0.1 0.0017 17.6 0.0 2.7 2 1 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 EPS32861.1 - 6.6e-09 36.2 0.5 0.06 13.6 0.0 4.3 2 2 1 3 3 3 2 AAA domain CDC48_2 PF02933.17 EPS32861.1 - 1.5e-07 31.0 0.0 3.9e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 RNA_helicase PF00910.22 EPS32861.1 - 5.8e-07 29.9 0.0 0.028 14.8 0.0 2.9 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 EPS32861.1 - 7.5e-07 28.7 0.7 0.038 13.4 0.1 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EPS32861.1 - 7.7e-07 29.0 0.0 0.025 14.3 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Vps4_C PF09336.10 EPS32861.1 - 8.5e-07 28.9 0.0 1.5e-05 24.9 0.0 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_18 PF13238.6 EPS32861.1 - 1.3e-06 29.0 0.0 0.054 14.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 EPS32861.1 - 1.5e-06 28.3 0.0 0.015 15.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 EPS32861.1 - 1.8e-06 27.5 0.3 0.52 9.6 0.0 3.4 3 0 0 3 3 3 2 KaiC AAA_7 PF12775.7 EPS32861.1 - 1.6e-05 24.5 0.1 0.11 12.0 0.0 2.9 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_24 PF13479.6 EPS32861.1 - 1.8e-05 24.6 0.0 0.13 12.0 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.6 EPS32861.1 - 1.9e-05 24.4 5.5 1.8 8.1 0.1 5.0 3 2 1 5 5 5 1 AAA domain Parvo_NS1 PF01057.17 EPS32861.1 - 3e-05 23.3 0.1 0.1 11.7 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 DUF815 PF05673.13 EPS32861.1 - 3.3e-05 23.2 0.0 0.024 13.8 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 EPS32861.1 - 4.3e-05 23.8 0.0 0.3 11.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 EPS32861.1 - 4.4e-05 23.2 0.0 0.46 10.2 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain TsaE PF02367.17 EPS32861.1 - 9.5e-05 22.4 0.0 0.59 10.2 0.0 3.0 2 1 1 3 3 3 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Bac_DnaA PF00308.18 EPS32861.1 - 0.00016 21.6 0.0 0.5 10.2 0.0 3.0 3 0 0 3 3 2 2 Bacterial dnaA protein AAA_17 PF13207.6 EPS32861.1 - 0.00026 21.4 0.1 0.59 10.6 0.0 3.2 3 1 0 3 3 2 1 AAA domain ResIII PF04851.15 EPS32861.1 - 0.00027 21.0 0.0 0.075 13.0 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ABC_tran PF00005.27 EPS32861.1 - 0.00029 21.3 0.0 0.82 10.2 0.0 3.4 2 1 0 2 2 2 1 ABC transporter PhoH PF02562.16 EPS32861.1 - 0.00034 20.1 1.8 0.46 9.9 0.0 2.8 3 0 0 3 3 2 2 PhoH-like protein AAA_3 PF07726.11 EPS32861.1 - 0.00056 19.8 0.0 1.1 9.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 EPS32861.1 - 0.00061 19.7 0.0 1.4 8.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 EPS32861.1 - 0.00076 18.8 0.0 0.9 8.7 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) ATPase_2 PF01637.18 EPS32861.1 - 0.0012 18.9 0.0 2.7 7.9 0.0 3.6 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_30 PF13604.6 EPS32861.1 - 0.0017 18.1 0.3 1.6 8.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EPS32861.1 - 0.0018 18.2 0.1 1.2 9.0 0.0 3.0 3 0 0 3 3 3 1 NACHT domain Viral_helicase1 PF01443.18 EPS32861.1 - 0.0066 16.2 0.0 0.67 9.7 0.0 2.7 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 EPS32861.1 - 0.0069 16.7 0.6 8.2 6.7 0.0 3.4 3 1 0 4 4 2 0 AAA domain UFD1 PF03152.14 EPS32861.1 - 0.0099 15.4 0.0 0.086 12.3 0.0 2.1 1 1 1 2 2 2 1 Ubiquitin fusion degradation protein UFD1 NB-ARC PF00931.22 EPS32861.1 - 0.011 15.0 0.0 2.2 7.4 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain Zeta_toxin PF06414.12 EPS32861.1 - 0.018 14.3 0.0 6.1 6.1 0.0 2.8 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.15 EPS32861.1 - 0.02 14.8 1.5 4.1 7.3 0.0 4.2 5 0 0 5 5 4 0 NTPase KAP_NTPase PF07693.14 EPS32861.1 - 0.022 14.0 0.3 1.2 8.3 0.0 2.8 2 2 0 3 3 3 0 KAP family P-loop domain Sigma54_activ_2 PF14532.6 EPS32861.1 - 0.026 14.6 0.0 4.1 7.5 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain IPT PF01745.16 EPS32861.1 - 0.031 13.7 0.0 2.4 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Zot PF05707.12 EPS32861.1 - 0.042 13.5 0.1 2.5 7.7 0.0 3.2 2 2 0 2 2 2 0 Zonular occludens toxin (Zot) Cytidylate_kin2 PF13189.6 EPS32861.1 - 0.089 12.9 0.0 3.5 7.7 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase-like family AAA_6 PF12774.7 EPS32861.1 - 0.098 11.6 0.1 9.1 5.1 0.0 2.4 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region eIF-1a PF01176.19 EPS32861.1 - 0.22 11.4 1.1 1.8 8.5 0.2 2.6 1 1 1 2 2 2 0 Translation initiation factor 1A / IF-1 PEX11 PF05648.14 EPS32862.1 - 1.1e-14 54.4 0.4 1.3e-11 44.4 0.0 2.1 2 0 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) DUF1217 PF06748.12 EPS32863.1 - 0.14 12.2 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1217) Mpv17_PMP22 PF04117.12 EPS32864.1 - 4.7e-13 49.1 0.9 1.6e-11 44.2 0.6 2.3 2 0 0 2 2 2 2 Mpv17 / PMP22 family Cullin_binding PF03556.15 EPS32865.1 - 1e-31 109.9 1.3 1.8e-31 109.1 1.3 1.4 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 EPS32865.1 - 9.9e-14 50.9 0.9 3.4e-13 49.2 1.0 1.9 2 0 0 2 2 2 1 UBA-like domain TAP_C PF03943.13 EPS32865.1 - 0.11 12.2 0.2 0.24 11.0 0.2 1.6 1 0 0 1 1 1 0 TAP C-terminal domain UPF0113 PF03657.13 EPS32866.1 - 1.1e-24 86.4 0.0 1.6e-24 85.9 0.0 1.2 1 0 0 1 1 1 1 UPF0113 PUA domain UPF0113_N PF17833.1 EPS32866.1 - 4.6e-24 84.8 0.0 6.6e-24 84.3 0.0 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain PUA PF01472.20 EPS32866.1 - 0.03 14.3 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 PUA domain NOC3p PF07540.11 EPS32867.1 - 1.9e-31 108.4 0.1 7.8e-31 106.4 0.1 2.2 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.17 EPS32867.1 - 5.5e-25 88.3 0.9 5.5e-25 88.3 0.9 2.9 2 1 0 2 2 2 1 CBF/Mak21 family RICTOR_N PF14664.6 EPS32867.1 - 0.016 14.2 0.1 0.04 12.9 0.0 1.6 1 1 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term Tmemb_cc2 PF10267.9 EPS32868.1 - 0.002 17.4 5.1 0.002 17.4 5.1 1.5 2 0 0 2 2 2 1 Predicted transmembrane and coiled-coil 2 protein Fib_alpha PF08702.10 EPS32868.1 - 0.047 13.9 5.8 0.61 10.3 2.9 2.3 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family IFP_35_N PF07334.13 EPS32868.1 - 0.078 13.1 2.0 0.17 12.0 0.5 2.4 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus GPS2_interact PF15784.5 EPS32868.1 - 0.17 12.3 7.6 0.31 11.5 1.2 3.3 2 1 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain UPF0242 PF06785.11 EPS32868.1 - 0.24 11.5 7.2 4.7 7.3 7.0 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Strep_SA_rep PF06696.11 EPS32868.1 - 0.24 11.4 1.4 0.36 10.9 0.1 1.9 2 0 0 2 2 2 0 Streptococcal surface antigen repeat RasGAP_C PF03836.15 EPS32868.1 - 0.26 11.4 2.7 0.29 11.3 0.7 2.1 2 0 0 2 2 2 0 RasGAP C-terminus CCDC53 PF10152.9 EPS32868.1 - 0.43 11.0 0.0 0.43 11.0 0.0 3.5 3 2 0 3 3 3 0 Subunit CCDC53 of WASH complex HMMR_N PF15905.5 EPS32868.1 - 0.76 9.2 13.2 1.4 8.3 13.2 1.4 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal FapA PF03961.13 EPS32868.1 - 0.89 8.1 3.4 1.3 7.6 3.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A TelA PF05816.11 EPS32868.1 - 1 8.4 13.1 0.25 10.4 3.4 2.1 1 1 1 2 2 2 0 Toxic anion resistance protein (TelA) LPP PF04728.13 EPS32868.1 - 1.5 9.3 4.9 36 4.9 0.2 3.6 2 1 0 3 3 3 0 Lipoprotein leucine-zipper FlaC_arch PF05377.11 EPS32868.1 - 2.2 8.7 8.0 14 6.2 0.1 3.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) TMF_DNA_bd PF12329.8 EPS32868.1 - 2.9 8.0 8.2 0.57 10.2 0.1 3.1 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding BAR PF03114.18 EPS32872.1 - 0.098 12.3 0.1 0.33 10.6 0.1 1.8 1 1 1 2 2 2 0 BAR domain RELT PF12606.8 EPS32874.1 - 0.51 9.4 3.0 0.96 8.5 3.0 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 ATP-synt_C PF00137.21 EPS32875.1 - 5e-09 36.4 13.2 1e-08 35.4 13.2 1.5 1 0 0 1 1 1 1 ATP synthase subunit C DUF1349 PF07081.11 EPS32877.1 - 1e-19 71.0 0.0 5.1e-18 65.4 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1349) RcnB PF11776.8 EPS32877.1 - 0.096 12.8 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Nickel/cobalt transporter regulator Cript PF10235.9 EPS32879.1 - 1.2e-24 86.7 11.6 1.2e-24 86.7 11.6 1.8 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT DZR PF12773.7 EPS32879.1 - 0.0021 18.1 15.7 0.0067 16.4 9.7 2.6 1 1 1 2 2 2 2 Double zinc ribbon zinc_ribbon_15 PF17032.5 EPS32879.1 - 0.022 15.5 12.9 0.061 14.1 9.4 2.6 2 1 0 2 2 2 0 zinc-ribbon family CEBP_ZZ PF16366.5 EPS32879.1 - 0.029 14.6 4.6 0.029 14.6 4.6 1.9 2 0 0 2 2 2 0 Cytoplasmic polyadenylation element-binding protein ZZ domain zinc-ribbons_6 PF07191.12 EPS32879.1 - 0.031 14.3 9.2 0.19 11.8 5.5 2.3 2 0 0 2 2 2 0 zinc-ribbons zf-4CXXC_R1 PF10497.9 EPS32879.1 - 0.042 14.1 5.8 0.042 14.1 5.8 1.8 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 DUF2321 PF10083.9 EPS32879.1 - 0.046 13.3 1.9 0.078 12.6 1.9 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) zinc_ribbon_2 PF13240.6 EPS32879.1 - 0.059 13.1 14.5 2 8.3 4.3 3.4 3 0 0 3 3 3 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 EPS32879.1 - 0.11 11.9 11.0 1.3 8.5 0.2 3.3 3 0 0 3 3 3 0 zinc-ribbon domain CTX_RstB PF07459.11 EPS32879.1 - 0.11 12.7 0.1 0.19 12.0 0.1 1.4 1 0 0 1 1 1 0 CTX phage RstB protein Prok-RING_4 PF14447.6 EPS32879.1 - 0.4 10.6 9.8 4 7.4 6.6 2.9 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-HYPF PF07503.12 EPS32879.1 - 0.71 9.7 11.3 1.6 8.6 7.0 2.4 2 0 0 2 2 2 0 HypF finger DUF2039 PF10217.9 EPS32879.1 - 1.5 9.2 18.7 0.46 10.9 11.9 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) zf_UBZ PF18439.1 EPS32879.1 - 3.8 7.2 13.4 2.2 8.0 0.1 4.0 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger zf-C3HC4_3 PF13920.6 EPS32879.1 - 4.1 7.3 15.0 55 3.7 0.1 3.0 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF1272 PF06906.11 EPS32879.1 - 5.8 7.1 14.3 12 6.1 9.7 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1272) DUF983 PF06170.12 EPS32879.1 - 8.7 6.8 8.7 2.3 8.7 0.3 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF983) zf-RING_5 PF14634.6 EPS32879.1 - 9.3 6.3 14.4 82 3.3 0.1 3.0 2 1 0 2 2 2 0 zinc-RING finger domain MRP-L46 PF11788.8 EPS32880.1 - 4.4e-38 130.7 0.3 9e-38 129.7 0.3 1.5 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX_4 PF14815.6 EPS32880.1 - 0.00037 20.5 0.5 0.001 19.0 0.2 1.9 2 0 0 2 2 2 1 NUDIX domain NUDIX PF00293.28 EPS32880.1 - 0.0045 17.0 0.0 0.0088 16.1 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain CAF1 PF04857.20 EPS32881.1 - 6.5e-79 265.4 0.0 7.9e-79 265.1 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.20 EPS32881.1 - 0.019 14.7 0.1 0.14 11.9 0.0 2.1 2 0 0 2 2 2 0 3'-5' exonuclease ATP1G1_PLM_MAT8 PF02038.16 EPS32882.1 - 0.13 11.7 0.1 0.27 10.7 0.1 1.4 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family DUF572 PF04502.13 EPS32882.1 - 0.24 11.0 6.9 0.48 10.0 6.9 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) Peptidase_S30 PF01577.16 EPS32882.1 - 0.25 10.9 3.5 0.43 10.1 3.5 1.4 1 0 0 1 1 1 0 Potyvirus P1 protease Pex26 PF07163.12 EPS32882.1 - 0.76 9.0 3.4 0.38 10.0 0.9 1.7 2 0 0 2 2 2 0 Pex26 protein adh_short PF00106.25 EPS32883.1 - 5.2e-36 123.9 0.0 7.1e-36 123.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS32883.1 - 8.1e-27 94.3 0.0 1e-26 93.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPS32883.1 - 0.0013 18.7 0.0 0.002 18.1 0.0 1.3 1 0 0 1 1 1 1 KR domain SBF_like PF13593.6 EPS32884.1 - 1.9e-88 296.8 20.9 2.2e-88 296.6 20.9 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 EPS32884.1 - 1.9e-11 44.0 8.1 1.9e-11 44.0 8.1 1.5 1 1 0 1 1 1 1 Sodium Bile acid symporter family Mito_carr PF00153.27 EPS32886.1 - 7.7e-66 218.1 1.9 2.2e-22 78.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Cofilin_ADF PF00241.20 EPS32887.1 - 1.9e-26 92.3 0.0 4.2e-14 52.4 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein PHF5 PF03660.14 EPS32888.1 - 1.1e-52 176.6 10.3 1.2e-52 176.4 10.3 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 EPS32888.1 - 0.6 7.9 7.5 0.62 7.9 7.5 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DZR PF12773.7 EPS32888.1 - 2.2 8.4 15.9 6.8 6.8 2.3 3.1 1 1 1 2 2 2 0 Double zinc ribbon Pinin_SDK_memA PF04696.13 EPS32889.1 - 1.8e-30 105.7 10.1 3.7e-30 104.7 10.1 1.5 1 0 0 1 1 1 1 pinin/SDK/memA/ protein conserved region Abhydrolase_1 PF00561.20 EPS32890.1 - 1.2e-19 71.0 0.3 1.6e-18 67.3 0.3 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPS32890.1 - 2.8e-14 54.2 0.1 4e-14 53.8 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPS32890.1 - 3.1e-12 46.3 0.1 2.2e-09 36.9 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 EPS32890.1 - 0.035 14.2 0.0 0.07 13.3 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein TUDOR_5 PF18359.1 EPS32890.1 - 0.045 13.5 0.0 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 Histone methyltransferase Tudor domain 1 Tudor_3 PF18115.1 EPS32890.1 - 0.13 12.1 0.1 0.38 10.6 0.1 1.7 1 0 0 1 1 1 0 DNA repair protein Crb2 Tudor domain Sacchrp_dh_NADP PF03435.18 EPS32891.1 - 2.2e-17 63.5 0.0 3.5e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Ribosomal_L37ae PF01780.19 EPS32892.1 - 1.5e-40 137.1 10.1 1.7e-40 137.0 10.1 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 EPS32892.1 - 0.00061 19.9 1.9 0.00085 19.4 1.9 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain DUF1451 PF07295.11 EPS32892.1 - 0.019 15.0 0.6 0.026 14.5 0.6 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain Zn_Tnp_IS1595 PF12760.7 EPS32892.1 - 0.041 13.9 2.8 0.074 13.0 2.8 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.10 EPS32892.1 - 0.092 12.5 3.1 4.6 7.1 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-BED PF02892.15 EPS32892.1 - 0.23 11.5 5.5 2.4 8.3 0.5 2.2 1 1 1 2 2 2 0 BED zinc finger zf-RING_2 PF13639.6 EPS32893.1 - 6e-09 36.1 0.6 6e-09 36.1 0.6 3.3 3 0 0 3 3 3 1 Ring finger domain PHD PF00628.29 EPS32893.1 - 1e-08 34.9 14.5 2.5e-08 33.7 7.8 2.6 2 0 0 2 2 2 1 PHD-finger Prok-RING_4 PF14447.6 EPS32893.1 - 1e-06 28.5 1.0 1e-06 28.5 1.0 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EPS32893.1 - 1.4e-06 28.5 0.3 1.4e-06 28.5 0.3 2.2 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EPS32893.1 - 4.1e-05 23.4 1.3 4.1e-05 23.4 1.3 2.5 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EPS32893.1 - 4.4e-05 23.3 0.1 4.4e-05 23.3 0.1 2.8 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EPS32893.1 - 7.6e-05 22.5 1.7 7.6e-05 22.5 1.7 2.4 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EPS32893.1 - 0.00017 21.3 0.6 0.00017 21.3 0.6 3.1 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.6 EPS32893.1 - 0.00025 20.5 1.8 0.00071 19.1 1.8 1.8 1 0 0 1 1 1 1 PHD-finger zf-ANAPC11 PF12861.7 EPS32893.1 - 0.007 16.4 0.1 0.007 16.4 0.1 1.8 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EPS32893.1 - 0.014 15.0 0.5 0.014 15.0 0.5 2.3 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Astacin PF01400.24 EPS32893.1 - 0.027 14.1 0.2 0.22 11.1 0.2 1.9 1 1 0 1 1 1 0 Astacin (Peptidase family M12A) zf-C2HC_2 PF13913.6 EPS32893.1 - 0.64 10.0 3.7 1.6 8.7 0.3 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Abhydrolase_3 PF07859.13 EPS32895.1 - 2.5e-43 148.4 0.0 3.3e-43 148.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EPS32895.1 - 1.9e-09 37.0 0.5 4.8e-09 35.6 0.5 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.7 EPS32895.1 - 0.00029 21.5 1.4 0.00046 20.8 1.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 EPS32895.1 - 0.037 13.6 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EPS32895.1 - 0.18 11.2 0.0 6.4 6.2 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family GMC_oxred_N PF00732.19 EPS32896.1 - 2.7e-58 197.7 0.0 3.7e-58 197.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EPS32896.1 - 1e-30 107.1 0.0 1.8e-30 106.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 EPS32896.1 - 0.00023 21.3 0.0 0.00059 20.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EPS32896.1 - 0.0083 15.2 1.7 0.13 11.3 1.2 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 EPS32896.1 - 0.013 14.6 0.2 0.035 13.2 0.2 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EPS32896.1 - 0.014 14.6 0.1 0.15 11.3 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF4926 PF16277.5 EPS32896.1 - 0.13 11.6 0.0 0.29 10.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4926) Pyr_redox_3 PF13738.6 EPS32896.1 - 0.15 11.3 0.2 0.34 10.1 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EPS32896.1 - 0.21 11.2 3.5 0.67 9.5 0.5 2.8 2 1 1 3 3 3 0 FAD dependent oxidoreductase EnY2 PF10163.9 EPS32897.1 - 1.5e-05 25.3 0.0 2.7e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Transcription factor e(y)2 SAM_2 PF07647.17 EPS32898.1 - 1.1e-15 57.5 0.0 1.9e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EPS32898.1 - 7.1e-14 52.0 0.0 1.2e-13 51.3 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.23 EPS32898.1 - 5.4e-13 49.4 0.0 9.9e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Angiomotin_C PF12240.8 EPS32898.1 - 0.012 15.2 0.2 0.021 14.4 0.2 1.3 1 0 0 1 1 1 0 Angiomotin C terminal MCPVI PF02993.14 EPS32898.1 - 0.067 13.0 0.1 0.71 9.7 0.0 2.2 2 0 0 2 2 2 0 Minor capsid protein VI SAM_4 PF18017.1 EPS32898.1 - 0.1 12.6 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) PI3K_P85_iSH2 PF16454.5 EPS32898.1 - 0.13 11.9 0.2 0.21 11.2 0.2 1.2 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain FokI_N PF02981.15 EPS32898.1 - 0.23 11.6 0.1 0.75 10.0 0.0 1.8 2 0 0 2 2 2 0 Restriction endonuclease FokI, recognition domain GNT-I PF03071.15 EPS32898.1 - 0.23 10.2 0.1 0.33 9.7 0.1 1.1 1 0 0 1 1 1 0 GNT-I family Polysacc_deac_1 PF01522.21 EPS32900.1 - 7.2e-28 97.0 0.0 1.3e-27 96.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.19 EPS32900.1 - 4.5e-06 27.0 44.0 1.1e-05 25.8 15.9 2.7 2 1 0 2 2 2 2 Chitin recognition protein HrcA_DNA-bdg PF03444.15 EPS32900.1 - 0.22 11.2 0.0 0.44 10.2 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding HEAT_2 PF13646.6 EPS32901.1 - 0.00012 22.4 0.4 0.03 14.7 0.1 3.2 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.22 EPS32901.1 - 0.00022 21.2 0.1 0.53 10.7 0.0 4.2 5 0 0 5 5 5 1 HEAT repeat UME PF08064.13 EPS32901.1 - 0.00035 20.4 0.0 1 9.3 0.0 3.7 2 2 1 3 3 3 1 UME (NUC010) domain HEAT_EZ PF13513.6 EPS32901.1 - 0.00039 20.8 4.6 0.66 10.5 0.0 5.4 5 2 2 7 7 7 1 HEAT-like repeat RTP1_C1 PF10363.9 EPS32901.1 - 0.0046 17.1 0.2 0.017 15.3 0.0 1.9 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 EPS32901.1 - 0.0047 15.6 0.3 0.37 9.3 0.0 2.8 2 1 1 3 3 3 1 Adaptin N terminal region IFRD PF05004.13 EPS32901.1 - 0.0057 15.8 0.2 1.8 7.6 0.0 2.2 2 0 0 2 2 2 2 Interferon-related developmental regulator (IFRD) DUF3385 PF11865.8 EPS32901.1 - 0.011 15.7 0.0 0.66 9.9 0.0 2.8 2 2 0 2 2 2 0 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.7 EPS32901.1 - 0.038 14.6 0.0 0.21 12.2 0.0 2.2 3 0 0 3 3 2 0 Vacuolar 14 Fab1-binding region Cnd3 PF12719.7 EPS32901.1 - 0.053 12.7 0.0 0.14 11.4 0.0 1.6 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain Proteasom_PSMB PF10508.9 EPS32901.1 - 0.12 10.8 0.0 0.31 9.5 0.0 1.6 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit DUF3718 PF12514.8 EPS32904.1 - 0.022 14.9 0.0 0.026 14.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3718) Glyoxalase_3 PF13468.6 EPS32906.1 - 1.4e-23 83.9 0.1 1.9e-23 83.5 0.1 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain TRAM_LAG1_CLN8 PF03798.16 EPS32909.1 - 5e-39 134.1 18.3 5e-39 134.1 18.3 1.7 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.11 EPS32909.1 - 1.8e-23 81.9 0.0 5.4e-23 80.4 0.0 1.9 1 0 0 1 1 1 1 TRAM1-like protein Sugar_tr PF00083.24 EPS32910.1 - 2e-111 373.0 21.1 2.4e-111 372.8 21.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS32910.1 - 4.3e-25 88.4 33.8 4.9e-25 88.2 25.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Transglut_core PF01841.19 EPS32912.1 - 3.4e-13 50.0 0.0 5.8e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily Gln_amidase PF15644.6 EPS32912.1 - 0.03 15.3 0.1 0.094 13.7 0.1 2.0 1 1 0 1 1 1 0 Papain fold toxin 1, glutamine deamidase DUF553 PF04473.12 EPS32912.1 - 0.096 12.2 0.1 1.7 8.1 0.1 2.6 1 1 0 1 1 1 0 Transglutaminase-like domain Ras PF00071.22 EPS32914.1 - 4.9e-31 107.5 0.2 6.4e-31 107.1 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EPS32914.1 - 1.5e-23 83.3 0.1 2.5e-23 82.6 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPS32914.1 - 1.4e-06 27.9 0.1 1.8e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EPS32914.1 - 0.00023 20.6 0.2 0.00032 20.1 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 EPS32914.1 - 0.0026 16.7 0.1 1.4 7.6 0.0 2.2 2 0 0 2 2 2 2 Dynein light intermediate chain (DLIC) zf-C2H2_assoc2 PF16624.5 EPS32914.1 - 0.79 10.8 4.6 0.3 12.1 0.4 2.3 1 1 2 3 3 3 0 Unstructured region upstream of a zinc-finger CAF1C_H4-bd PF12265.8 EPS32916.1 - 6.9e-17 61.5 0.0 4.8e-16 58.8 0.0 2.4 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EPS32916.1 - 1.2e-15 57.6 8.5 9.6e-07 29.4 0.1 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS32916.1 - 1.8e-09 37.8 1.8 0.00025 21.3 0.3 3.1 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain UL41A PF17591.2 EPS32916.1 - 0.17 12.0 0.0 0.56 10.4 0.0 1.8 1 0 0 1 1 1 0 Herpesvirus UL41A Fungal_trans PF04082.18 EPS32920.1 - 4.2e-24 85.0 1.9 7.4e-24 84.2 1.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EPS32920.1 - 1.4e-09 37.8 12.6 0.00025 21.3 4.0 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EPS32920.1 - 6.4e-08 32.7 12.2 9e-07 29.1 5.8 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 EPS32920.1 - 0.0081 16.9 18.9 0.057 14.3 3.2 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EPS32920.1 - 0.13 12.3 3.8 0.34 11.0 3.8 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EPS32920.1 - 0.23 11.8 2.0 0.82 10.0 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_11 PF16622.5 EPS32920.1 - 2.2 8.1 8.0 10 6.0 1.5 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type Clathrin PF00637.20 EPS32922.1 - 1.6e-23 83.2 0.3 2.2e-21 76.3 0.3 2.5 2 0 0 2 2 2 1 Region in Clathrin and VPS VPS11_C PF12451.8 EPS32922.1 - 6.4e-19 67.9 0.7 1.5e-18 66.7 0.7 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 EPS32922.1 - 3.4e-07 30.2 6.0 6.2e-07 29.4 6.0 1.4 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 EPS32922.1 - 8e-06 25.6 6.2 1.7e-05 24.6 6.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_14 PF13428.6 EPS32922.1 - 1.5e-05 25.4 0.1 0.019 15.8 0.0 3.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EPS32922.1 - 0.00076 19.1 0.1 0.0023 17.6 0.1 1.8 1 0 0 1 1 1 1 TPR repeat zf-RING_5 PF14634.6 EPS32922.1 - 0.0018 18.2 5.8 0.0037 17.2 5.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EPS32922.1 - 0.0022 18.3 6.8 0.0041 17.4 6.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EPS32922.1 - 0.019 15.2 4.4 0.038 14.3 4.4 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain TPR_16 PF13432.6 EPS32922.1 - 0.02 15.5 0.1 0.075 13.7 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-C3HC4 PF00097.25 EPS32922.1 - 0.036 13.9 5.0 0.068 13.1 5.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_2 PF07719.17 EPS32922.1 - 0.037 14.1 2.2 0.096 12.9 0.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Vps39_2 PF10367.9 EPS32922.1 - 0.044 14.2 2.4 0.15 12.6 0.3 2.5 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 DUF4810 PF16068.5 EPS32922.1 - 0.047 14.2 0.4 21 5.8 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4810) CdiI_2 PF18593.1 EPS32922.1 - 0.11 13.1 0.4 21 5.9 0.0 3.5 3 0 0 3 3 3 0 CdiI immunity protein EF-hand_like PF09279.11 EPS32922.1 - 0.65 10.5 2.8 3.2 8.3 0.1 3.3 3 1 1 4 4 4 0 Phosphoinositide-specific phospholipase C, efhand-like zf-RING_UBOX PF13445.6 EPS32922.1 - 1.6 8.8 6.5 3.9 7.6 6.5 1.7 1 0 0 1 1 1 0 RING-type zinc-finger ANAPC3 PF12895.7 EPS32922.1 - 6.2 7.1 5.6 2.7 8.3 0.3 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Nha1_C PF08619.10 EPS32923.1 - 3.8e-104 349.5 50.1 6.3e-104 348.8 50.1 1.3 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.21 EPS32923.1 - 3.4e-76 256.5 13.1 4e-76 256.3 13.1 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PRP4 PF08799.11 EPS32923.1 - 0.045 13.3 0.6 0.17 11.5 0.6 2.1 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like DUF21 PF01595.20 EPS32923.1 - 0.35 10.6 4.5 0.29 10.8 1.6 2.2 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain Colicin_E5 PF12106.8 EPS32923.1 - 0.49 10.7 5.8 2.3 8.6 0.0 3.3 4 0 0 4 4 4 0 Colicin E5 ribonuclease domain PX PF00787.24 EPS32924.1 - 2.3e-17 63.0 0.1 4.3e-17 62.1 0.1 1.4 1 0 0 1 1 1 1 PX domain Tmemb_cc2 PF10267.9 EPS32924.1 - 0.0037 16.5 0.3 0.0063 15.7 0.3 1.3 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Pro_dh PF01619.18 EPS32925.1 - 2.5e-59 201.3 0.0 2.9e-59 201.0 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase Fungal_trans PF04082.18 EPS32926.1 - 1.8e-10 40.3 0.0 4.3e-10 39.1 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS32926.1 - 2.8e-08 33.7 9.0 5.3e-08 32.8 9.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATG2_CAD PF13329.6 EPS32926.1 - 0.026 14.3 1.4 0.048 13.4 1.4 1.3 1 0 0 1 1 1 0 Autophagy-related protein 2 CAD motif AAA PF00004.29 EPS32927.1 - 8.9e-06 26.2 0.2 6.1e-05 23.5 0.2 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EPS32927.1 - 1.9e-05 24.7 0.4 0.0031 17.5 0.0 3.2 3 0 0 3 3 3 1 Rad17 P-loop domain AAA_16 PF13191.6 EPS32927.1 - 0.00066 20.1 0.0 0.0013 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EPS32927.1 - 0.0068 16.7 0.0 0.016 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EPS32927.1 - 0.029 13.4 0.0 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.6 EPS32927.1 - 0.098 13.2 0.0 0.29 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Utp8 PF10395.9 EPS32928.1 - 2.2e-10 39.7 0.3 1.2e-09 37.3 0.3 1.8 1 1 0 1 1 1 1 Utp8 family ArgoL1 PF08699.10 EPS32929.1 - 0.13 12.0 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Argonaute linker 1 domain LRR_4 PF12799.7 EPS32930.1 - 5.9e-25 86.9 41.2 6.3e-05 23.3 1.6 9.1 4 3 7 11 11 11 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EPS32930.1 - 3.4e-22 78.0 42.4 2.8e-06 27.0 0.5 7.1 3 1 6 9 9 9 8 Leucine rich repeat LRR_9 PF14580.6 EPS32930.1 - 1.7e-08 34.1 13.5 0.011 15.3 0.4 4.3 1 1 4 5 5 5 5 Leucine-rich repeat LRR_6 PF13516.6 EPS32930.1 - 1.2e-06 28.1 29.4 1.8 8.8 0.1 9.5 10 0 0 10 10 10 5 Leucine Rich repeat LRR_1 PF00560.33 EPS32930.1 - 4.1e-06 26.6 26.8 9.1 7.3 0.0 9.8 8 2 0 8 8 8 4 Leucine Rich Repeat MFS_1 PF07690.16 EPS32931.1 - 3e-31 108.6 32.6 2.5e-25 89.2 12.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TraL PF07178.11 EPS32931.1 - 2 8.9 13.1 2.5 8.6 1.0 3.9 3 0 0 3 3 3 0 TraL protein DAO PF01266.24 EPS32932.1 - 1.4e-39 136.7 0.1 1.7e-39 136.4 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EPS32932.1 - 0.00019 21.6 0.7 0.00069 19.8 0.5 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EPS32932.1 - 0.086 12.1 0.1 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.24 EPS32932.1 - 0.53 9.3 2.1 8.2 5.4 1.6 2.0 2 0 0 2 2 2 0 FAD binding domain LysM PF01476.20 EPS32933.1 - 1.6e-14 53.7 0.0 0.00011 22.2 0.0 3.4 3 0 0 3 3 3 3 LysM domain Methyltransf_31 PF13847.6 EPS32934.1 - 4.2e-28 98.0 0.0 5.2e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS32934.1 - 4.2e-24 85.0 0.1 7.4e-24 84.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPS32934.1 - 9.6e-24 83.9 0.2 1.7e-23 83.2 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPS32934.1 - 2.7e-16 59.6 0.0 3.9e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EPS32934.1 - 7.7e-16 58.6 0.1 1.3e-15 58.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPS32934.1 - 2.5e-12 47.0 0.0 3.9e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EPS32934.1 - 5.1e-09 36.2 0.0 7e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 EPS32934.1 - 6.3e-09 35.7 0.0 9.4e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 EPS32934.1 - 7.7e-09 35.3 0.0 1.1e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 EPS32934.1 - 4.3e-08 32.8 0.0 8.7e-08 31.8 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_9 PF08003.11 EPS32934.1 - 1.1e-06 27.9 0.3 9e-06 24.8 0.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) NodS PF05401.11 EPS32934.1 - 4.1e-05 23.3 0.0 6.4e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.20 EPS32934.1 - 0.00027 20.3 0.0 0.00046 19.6 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 EPS32934.1 - 0.00087 18.8 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.20 EPS32934.1 - 0.0023 17.1 0.0 0.0032 16.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DREV PF05219.12 EPS32934.1 - 0.003 16.7 0.0 0.0047 16.0 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase TehB PF03848.14 EPS32934.1 - 0.0041 16.5 0.0 0.0064 15.9 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB GidB PF02527.15 EPS32934.1 - 0.0073 15.6 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltr_RsmB-F PF01189.17 EPS32934.1 - 0.0086 15.7 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_2 PF00891.18 EPS32934.1 - 0.036 13.4 0.1 0.051 12.9 0.1 1.2 1 0 0 1 1 1 0 O-methyltransferase domain Methyltransf_32 PF13679.6 EPS32934.1 - 0.077 13.0 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.18 EPS32934.1 - 0.14 11.8 0.9 1.5 8.5 0.4 2.4 2 1 0 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.7 EPS32934.1 - 0.18 11.7 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Sulfatase PF00884.23 EPS32935.1 - 2.7e-18 66.4 0.6 9.3e-18 64.7 0.2 1.9 2 0 0 2 2 2 1 Sulfatase Phosphodiest PF01663.22 EPS32935.1 - 2e-05 24.4 0.0 3.6e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.17 EPS32935.1 - 0.024 13.3 0.0 0.032 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Glyco_hydro_62 PF03664.13 EPS32936.1 - 9e-151 500.8 12.9 1e-150 500.5 12.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 TIP120 PF08623.10 EPS32937.1 - 3.6e-63 212.3 0.1 1.6e-62 210.2 0.0 2.2 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) Rpr2 PF04032.16 EPS32937.1 - 1.5e-09 38.0 3.2 2.4e-09 37.4 2.0 2.1 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain HEAT PF02985.22 EPS32937.1 - 1.3e-05 25.1 12.9 1.4 9.4 0.0 8.5 9 0 0 9 9 9 3 HEAT repeat HEAT_EZ PF13513.6 EPS32937.1 - 0.0013 19.2 11.2 6.1 7.5 0.0 6.4 6 0 0 6 6 6 2 HEAT-like repeat TAF6_C PF07571.13 EPS32937.1 - 0.011 16.0 0.4 0.35 11.2 0.0 3.6 5 0 0 5 5 5 0 TAF6 C-terminal HEAT repeat domain FYVE PF01363.21 EPS32937.1 - 0.011 15.8 4.6 0.026 14.7 4.6 1.5 1 0 0 1 1 1 0 FYVE zinc finger DBR1 PF05011.13 EPS32938.1 - 3.1e-36 124.9 0.8 7.7e-35 120.3 0.0 2.3 1 1 1 2 2 2 2 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 EPS32938.1 - 8.7e-09 36.2 0.3 1.7e-08 35.2 0.3 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RTP1_C1 PF10363.9 EPS32939.1 - 2e-31 108.5 0.2 2.3e-30 105.0 0.1 2.9 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 EPS32939.1 - 3.5e-10 39.4 0.0 1.2e-09 37.7 0.0 1.9 2 0 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 2 HEAT_EZ PF13513.6 EPS32939.1 - 0.054 14.0 3.9 3.7 8.1 0.0 4.7 5 0 0 5 5 5 0 HEAT-like repeat zf-ZPR1 PF03367.13 EPS32941.1 - 2.2e-99 329.9 0.0 1.4e-49 168.0 0.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain zf-RRPl_C4 PF17026.5 EPS32941.1 - 0.026 14.6 0.2 0.063 13.4 0.2 1.6 1 0 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type Pro_isomerase PF00160.21 EPS32942.1 - 2.3e-37 128.7 0.0 4.7e-37 127.7 0.0 1.5 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ORC6 PF05460.13 EPS32943.1 - 2.8e-87 293.3 0.0 3.2e-87 293.1 0.0 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) SOG2 PF10428.9 EPS32943.1 - 0.037 13.2 2.3 0.051 12.8 2.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Q_salvage PF10343.9 EPS32944.1 - 1.6e-137 457.7 0.0 2e-137 457.4 0.0 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family Interfer-bind PF09294.10 EPS32944.1 - 0.12 12.7 0.1 0.24 11.7 0.1 1.5 1 0 0 1 1 1 0 Interferon-alpha/beta receptor, fibronectin type III DUF1563 PF07599.11 EPS32944.1 - 0.12 12.4 0.1 0.25 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1563) GATase_7 PF13537.6 EPS32944.1 - 0.12 12.2 0.1 0.53 10.2 0.0 2.0 2 0 0 2 2 2 0 Glutamine amidotransferase domain ThiF PF00899.21 EPS32945.1 - 5.7e-73 245.3 0.2 1e-72 244.5 0.0 1.4 2 0 0 2 2 2 1 ThiF family UAE_UbL PF14732.6 EPS32945.1 - 3.9e-15 56.2 0.7 1.3e-14 54.5 0.2 2.2 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 EPS32945.1 - 3.7e-09 36.9 2.4 1.9e-05 24.8 0.5 2.5 1 1 1 2 2 2 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 EPS32945.1 - 4.5e-05 23.8 0.0 0.00027 21.3 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 EPS32945.1 - 0.0041 17.2 0.0 0.0098 16.0 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF3192 PF11399.8 EPS32945.1 - 0.042 13.8 0.1 0.093 12.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3192) DUF5315 PF17242.2 EPS32945.1 - 0.095 12.5 0.6 0.22 11.4 0.6 1.6 1 0 0 1 1 1 0 Disordered region of unknown function (DUF5315) Pyr_redox PF00070.27 EPS32945.1 - 0.18 12.4 0.4 0.86 10.2 0.1 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase adh_short_C2 PF13561.6 EPS32946.1 - 2.8e-39 135.1 0.1 5.1e-39 134.2 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPS32946.1 - 2e-36 125.3 2.2 8.4e-36 123.3 2.2 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPS32946.1 - 3.7e-11 43.2 1.5 9.6e-11 41.9 1.5 1.7 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EPS32946.1 - 4.6e-07 29.3 0.0 6e-07 28.9 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EPS32946.1 - 0.00042 19.6 0.6 0.0006 19.1 0.6 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EPS32946.1 - 0.0012 18.4 0.2 0.0033 16.9 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.17 EPS32946.1 - 0.0048 17.5 0.1 0.012 16.2 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 EPS32946.1 - 0.012 15.9 0.2 0.028 14.7 0.2 1.7 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EPS32946.1 - 0.039 14.0 0.2 0.28 11.2 0.1 2.1 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase GDP_Man_Dehyd PF16363.5 EPS32946.1 - 0.086 12.2 0.1 0.19 11.1 0.0 1.6 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase WASH-7_mid PF14744.6 EPS32946.1 - 0.2 10.7 0.0 0.33 10.0 0.0 1.3 1 0 0 1 1 1 0 WASH complex subunit 7 Skp1_POZ PF03931.15 EPS32947.1 - 9e-10 38.6 0.0 1.3e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain zf-C3HC4_3 PF13920.6 EPS32948.1 - 9.7e-10 38.2 11.3 1.6e-09 37.4 11.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EPS32948.1 - 0.059 13.3 12.3 0.11 12.4 12.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 TM_helix PF05552.12 EPS32948.1 - 3.2 7.8 4.5 0.58 10.2 0.6 1.8 2 0 0 2 2 2 0 Conserved TM helix Malic_M PF03949.15 EPS32949.1 - 1.1e-91 306.6 0.0 1.5e-91 306.2 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EPS32949.1 - 1.5e-65 220.4 0.4 2.4e-65 219.7 0.0 1.5 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain CFEM PF05730.11 EPS32950.1 - 2.6e-15 56.2 11.5 4.8e-15 55.4 11.5 1.4 1 0 0 1 1 1 1 CFEM domain Caprin-1_C PF12287.8 EPS32950.1 - 9.2 6.3 9.9 11 6.0 9.9 1.2 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term DNA_pol_delta_4 PF04081.13 EPS32951.1 - 2.1e-35 121.9 0.7 3.2e-35 121.3 0.7 1.4 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 Arrestin_C PF02752.22 EPS32953.1 - 1.4e-11 44.9 0.0 4e-11 43.5 0.0 1.7 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain DHO_dh PF01180.21 EPS32953.1 - 0.099 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase DUF4404 PF14357.6 EPS32954.1 - 0.025 15.2 0.2 0.028 15.0 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) tRNA_int_end_N2 PF12928.7 EPS32955.1 - 7e-29 99.8 0.0 1.3e-28 98.9 0.0 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 EPS32955.1 - 0.0076 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain ABATE PF07336.11 EPS32955.1 - 0.024 15.3 0.2 0.1 13.2 0.0 2.0 2 0 0 2 2 2 0 Putative stress-induced transcription regulator CAP_N PF01213.19 EPS32955.1 - 1.1 8.7 8.9 1.7 8.0 8.9 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 EPS32955.1 - 3.4 7.7 6.5 5.8 6.9 6.5 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator ThiF PF00899.21 EPS32956.1 - 3.7e-14 52.7 0.0 2e-13 50.3 0.0 2.2 1 1 0 1 1 1 1 ThiF family Rib_5-P_isom_A PF06026.14 EPS32957.1 - 7.5e-44 149.4 0.0 1.3e-43 148.5 0.0 1.4 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 EPS32957.1 - 0.011 15.7 0.1 5.8 6.8 0.1 2.2 2 0 0 2 2 2 0 DeoR C terminal sensor domain WD40 PF00400.32 EPS32958.1 - 1.3e-14 54.3 1.2 0.0023 18.7 0.3 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat SGL PF08450.12 EPS32958.1 - 0.00028 20.5 0.0 0.034 13.7 0.0 2.3 2 0 0 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region ANAPC4_WD40 PF12894.7 EPS32958.1 - 0.024 14.9 0.0 18 5.7 0.0 4.1 2 2 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain DUF4979 PF16351.5 EPS32958.1 - 0.13 12.5 0.0 0.46 10.7 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4979) ATP_bind_1 PF03029.17 EPS32959.1 - 8.5e-77 258.2 0.0 1.1e-76 257.8 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 EPS32959.1 - 0.001 18.1 0.0 0.0021 17.1 0.0 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_31 PF13614.6 EPS32959.1 - 0.0011 18.9 0.0 0.27 11.2 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EPS32959.1 - 0.0021 17.8 0.4 0.51 10.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EPS32959.1 - 0.0066 16.5 0.0 0.052 13.6 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 EPS32959.1 - 0.0072 16.5 0.0 0.026 14.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EPS32959.1 - 0.024 15.2 0.2 0.29 11.7 0.0 2.5 2 1 1 3 3 3 0 AAA domain CLP1_P PF16575.5 EPS32959.1 - 0.032 14.0 0.0 0.14 11.9 0.0 1.9 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_10 PF12846.7 EPS32959.1 - 0.035 13.0 0.0 0.055 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_22 PF13401.6 EPS32959.1 - 0.055 13.7 0.0 0.14 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EPS32959.1 - 0.068 13.6 1.6 0.28 11.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.12 EPS32959.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 EPS32959.1 - 0.19 12.1 0.0 0.47 10.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 EPS32959.1 - 1.6 9.2 0.0 1.6 9.2 0.0 2.5 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) RNase_P_Rpp14 PF01900.19 EPS32960.1 - 2.4e-38 130.5 0.0 3.4e-38 130.0 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family Citrate_synt PF00285.21 EPS32961.1 - 1.6e-20 73.5 0.0 5.1e-18 65.3 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain CoA_binding PF02629.19 EPS32961.1 - 6.1e-19 68.5 0.0 2.7e-18 66.4 0.0 2.1 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 EPS32961.1 - 5.1e-15 55.6 0.1 8.3e-15 54.9 0.1 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 EPS32961.1 - 5.6e-06 26.2 0.0 4.8e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Citrate_bind PF16114.5 EPS32963.1 - 2.9e-87 290.7 0.0 4.1e-87 290.3 0.0 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 EPS32963.1 - 8e-09 35.4 0.0 1.2e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain F-box-like PF12937.7 EPS32964.1 - 1.7e-07 31.0 1.8 2.8e-06 27.1 0.2 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EPS32964.1 - 0.00072 19.4 0.4 0.0042 16.9 0.0 2.3 2 0 0 2 2 2 1 F-box domain Asp PF00026.23 EPS32966.1 - 2e-74 250.9 7.8 2.6e-74 250.5 7.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EPS32966.1 - 6.1e-06 26.6 1.5 6.1e-06 26.6 1.5 3.8 4 1 0 4 4 4 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EPS32966.1 - 2.4e-05 24.9 1.7 0.016 15.8 0.6 3.0 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 EPS32966.1 - 0.018 14.9 0.0 0.056 13.2 0.0 1.9 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal CBM_1 PF00734.18 EPS32967.1 - 2.9e-13 49.5 14.6 2.9e-13 49.5 14.6 2.6 2 0 0 2 2 2 1 Fungal cellulose binding domain DPBB_1 PF03330.18 EPS32967.1 - 2.3e-07 31.0 0.4 2.3e-07 31.0 0.4 2.2 3 0 0 3 3 3 1 Lytic transglycolase Sporozoite_P67 PF05642.11 EPS32967.1 - 3.2 5.7 14.7 3.7 5.5 14.7 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Glyco_hydro_7 PF00840.20 EPS32968.1 - 5.5e-123 410.9 15.2 5.5e-123 410.9 15.2 2.7 2 1 0 2 2 2 1 Glycosyl hydrolase family 7 CBM_1 PF00734.18 EPS32968.1 - 3.1e-13 49.4 14.9 3.1e-13 49.4 14.9 3.5 3 0 0 3 3 3 1 Fungal cellulose binding domain Asp PF00026.23 EPS32969.1 - 5.9e-68 229.6 0.0 7.1e-68 229.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EPS32969.1 - 1.1e-08 35.5 0.8 6.2e-07 29.8 0.8 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EPS32969.1 - 1.7e-05 25.4 0.1 0.0022 18.6 0.0 2.9 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 EPS32969.1 - 0.0084 16.6 0.2 0.16 12.5 0.0 2.8 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease DUF1485 PF07364.12 EPS32970.1 - 2.8e-104 348.5 4.1 4.3e-104 347.8 4.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M81 MlrC_C PF07171.12 EPS32970.1 - 3.5e-55 186.9 0.1 5.3e-55 186.3 0.1 1.3 1 0 0 1 1 1 1 MlrC C-terminus APH PF01636.23 EPS32971.1 - 0.00033 20.7 0.8 0.00033 20.7 0.8 3.4 3 2 1 4 4 4 1 Phosphotransferase enzyme family eIF3_subunit PF08597.10 EPS32971.1 - 0.014 15.4 1.5 0.03 14.2 1.5 1.6 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Pkinase PF00069.25 EPS32971.1 - 0.022 14.1 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain Pkinase_Tyr PF07714.17 EPS32971.1 - 0.026 13.8 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase RIO1 PF01163.22 EPS32971.1 - 0.075 12.6 0.0 0.075 12.6 0.0 1.6 2 0 0 2 2 2 0 RIO1 family HSDR_N_2 PF13588.6 EPS32971.1 - 0.12 12.3 0.0 0.6 10.1 0.0 2.0 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) Peptidase_A4 PF01828.17 EPS32972.1 - 8e-83 277.0 13.4 9.4e-83 276.8 13.4 1.1 1 0 0 1 1 1 1 Peptidase A4 family CARDB PF07705.11 EPS32972.1 - 0.07 13.4 0.7 0.18 12.1 0.1 2.0 2 0 0 2 2 2 0 CARDB NAD_binding_8 PF13450.6 EPS32973.1 - 1.6e-11 44.2 0.0 4.2e-11 42.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EPS32973.1 - 9.1e-06 25.0 0.1 1.3e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EPS32973.1 - 9.2e-06 25.5 0.1 2e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EPS32973.1 - 1.2e-05 24.8 0.0 4.8e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.7 EPS32973.1 - 1.6e-05 24.5 0.0 3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EPS32973.1 - 3.1e-05 22.9 0.0 9.3e-05 21.3 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 EPS32973.1 - 0.00018 20.8 0.0 0.00026 20.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EPS32973.1 - 0.0011 18.3 0.1 0.0019 17.5 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 EPS32973.1 - 0.0026 17.1 0.0 0.0039 16.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPS32973.1 - 0.009 16.5 0.0 0.019 15.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EPS32973.1 - 0.013 14.4 0.3 0.034 13.0 0.1 1.7 2 0 0 2 2 2 0 Tryptophan halogenase GMC_oxred_N PF00732.19 EPS32973.1 - 0.016 14.6 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 GMC oxidoreductase NAD_binding_9 PF13454.6 EPS32973.1 - 0.024 14.6 0.2 0.069 13.1 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding ApbA PF02558.16 EPS32973.1 - 0.03 14.0 0.1 0.061 13.0 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 EPS32973.1 - 0.067 12.2 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein TrkA_N PF02254.18 EPS32973.1 - 0.13 12.5 0.1 0.25 11.6 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain Peptidase_C28 PF05408.11 EPS32974.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Foot-and-mouth virus L-proteinase DUSP PF06337.12 EPS32974.1 - 0.17 12.5 0.0 0.26 11.9 0.0 1.2 1 0 0 1 1 1 0 DUSP domain Peptidase_M35 PF02102.15 EPS32975.1 - 1.2e-181 603.4 20.4 1.4e-181 603.1 20.4 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.6 EPS32975.1 - 3.2e-42 144.5 8.1 3.2e-42 144.5 8.1 2.2 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase CARDB PF07705.11 EPS32975.1 - 0.035 14.4 1.3 0.088 13.1 0.1 2.3 2 1 1 3 3 3 0 CARDB Methyltransf_31 PF13847.6 EPS32976.1 - 0.00012 22.0 0.0 0.00014 21.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPS32976.1 - 0.13 13.0 0.0 0.21 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_28 PF00295.17 EPS32977.1 - 4.4e-122 407.2 20.0 5.1e-122 407.0 20.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 NosD PF05048.13 EPS32977.1 - 0.0026 17.1 11.4 0.005 16.1 11.4 1.4 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) NAD_binding_8 PF13450.6 EPS32978.1 - 1.2e-14 54.3 0.6 6.9e-14 51.8 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EPS32978.1 - 3.1e-07 29.9 0.0 2.5e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EPS32978.1 - 9.3e-07 28.7 0.0 9.6e-05 22.1 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EPS32978.1 - 8.5e-06 25.8 0.0 5.5e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 EPS32978.1 - 5e-05 22.2 0.1 0.00096 18.0 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 EPS32978.1 - 7.4e-05 23.2 0.1 0.21 12.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EPS32978.1 - 0.00012 21.3 0.1 0.00018 20.7 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.24 EPS32978.1 - 0.00016 21.1 0.2 0.0095 15.3 0.0 2.8 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase Thi4 PF01946.17 EPS32978.1 - 0.0046 16.2 0.0 0.0098 15.2 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 EPS32978.1 - 0.027 13.5 0.0 0.041 12.9 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.18 EPS32978.1 - 0.073 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 EPS32978.1 - 0.12 12.5 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 EPS32978.1 - 0.2 10.9 0.0 0.45 9.7 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 EPS32979.1 - 4.5e-29 101.5 38.5 1.1e-28 100.2 36.4 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 EPS32979.1 - 0.0002 20.8 19.3 0.00052 19.4 5.9 2.4 2 1 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB YiaAB PF05360.14 EPS32979.1 - 0.36 11.1 10.2 0.1 12.9 4.6 3.1 2 0 0 2 2 2 0 yiaA/B two helix domain M20_dimer PF07687.14 EPS32980.1 - 5.3e-05 23.1 0.0 0.00077 19.4 0.0 2.3 2 0 0 2 2 2 1 Peptidase dimerisation domain Fungal_trans_2 PF11951.8 EPS32981.1 - 9.4e-17 60.9 0.8 2e-07 30.2 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS32981.1 - 4.4e-09 36.3 8.2 9.4e-09 35.3 8.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2919 PF11143.8 EPS32981.1 - 0.052 13.9 0.0 0.14 12.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2919) DUF3237 PF11578.8 EPS32982.1 - 3.7e-47 159.9 0.0 4.2e-47 159.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Formyl_trans_N PF00551.19 EPS32983.1 - 9.3e-40 136.3 0.1 1.2e-39 135.9 0.1 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 EPS32983.1 - 3.5e-08 33.1 0.0 1.1e-07 31.5 0.0 1.9 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.6 EPS32983.1 - 3.2e-07 30.2 0.0 1e-06 28.6 0.0 2.0 1 1 0 1 1 1 1 ACT domain Glyco_hydro_7 PF00840.20 EPS32984.1 - 2.8e-207 688.7 14.3 4.2e-207 688.1 14.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.18 EPS32984.1 - 4.3e-13 49.0 12.2 4.3e-13 49.0 12.2 4.6 6 0 0 6 6 6 1 Fungal cellulose binding domain Dioxygenase_C PF00775.21 EPS32985.1 - 8.6e-40 136.1 0.0 1.1e-39 135.7 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.14 EPS32985.1 - 8.3e-25 86.5 0.0 1.3e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.6 EPS32985.1 - 0.018 15.3 0.0 0.068 13.4 0.0 1.9 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain SpaA PF17802.1 EPS32985.1 - 0.045 14.1 0.0 0.073 13.4 0.0 1.3 1 0 0 1 1 1 0 Prealbumin-like fold domain Lactonase PF10282.9 EPS32986.1 - 1.7e-22 80.2 0.0 2.1e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Abhydrolase_6 PF12697.7 EPS32988.1 - 5.1e-13 50.1 0.2 5.1e-13 50.1 0.2 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EPS32988.1 - 4.1e-11 43.0 0.0 9.1e-11 41.9 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EPS32988.1 - 2.1e-07 30.4 0.0 5.6e-07 29.1 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 EPS32988.1 - 9.2e-06 24.6 0.0 1.4e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.10 EPS32988.1 - 0.0021 18.1 0.0 0.22 11.6 0.0 3.0 4 0 0 4 4 4 1 TAP-like protein Esterase PF00756.20 EPS32988.1 - 0.011 15.3 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Metallophos PF00149.28 EPS32989.1 - 1.1e-34 120.7 0.0 2.2e-30 106.7 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 EPS32989.1 - 0.087 12.4 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain NmrA PF05368.13 EPS32990.1 - 3.4e-27 95.5 0.1 5.8e-27 94.8 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPS32990.1 - 7.4e-18 65.1 0.0 1.3e-17 64.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EPS32990.1 - 1.9e-06 27.5 0.6 1.3e-05 24.8 0.0 2.4 2 2 1 3 3 3 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 EPS32990.1 - 0.00064 19.2 0.5 0.0011 18.4 0.1 1.7 2 0 0 2 2 2 1 short chain dehydrogenase 3HCDH_N PF02737.18 EPS32990.1 - 0.005 16.7 0.1 0.011 15.6 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 EPS32990.1 - 0.025 13.6 0.0 0.043 12.8 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 EPS32990.1 - 0.029 14.3 0.4 0.053 13.4 0.1 1.7 2 0 0 2 2 2 0 KR domain DapB_N PF01113.20 EPS32990.1 - 0.039 14.1 0.1 0.096 12.8 0.1 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.17 EPS32990.1 - 0.04 14.5 0.3 0.1 13.2 0.1 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent GDP_Man_Dehyd PF16363.5 EPS32990.1 - 0.066 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 EPS32990.1 - 0.086 13.3 0.1 0.34 11.3 0.0 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DFP PF04127.15 EPS32990.1 - 0.1 12.4 0.6 0.22 11.3 0.2 1.7 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein RmlD_sub_bind PF04321.17 EPS32990.1 - 0.1 11.7 0.1 0.17 11.0 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_4 PF07993.12 EPS32990.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Polysacc_synt_2 PF02719.15 EPS32990.1 - 0.15 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Radical_SAM PF04055.21 EPS32991.1 - 3.8e-22 79.4 0.0 1.4e-21 77.6 0.0 2.0 1 1 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.12 EPS32991.1 - 1.9e-21 76.2 0.0 4.5e-21 75.0 0.0 1.7 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.25 EPS32991.1 - 3.4e-09 37.1 0.0 1.2e-05 25.6 0.0 2.5 2 0 0 2 2 2 2 Flavodoxin CcmD PF04995.14 EPS32991.1 - 1.2 9.3 5.8 3.8 7.7 5.8 1.9 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Peptidase_M19 PF01244.21 EPS32992.1 - 9.7e-105 350.2 0.0 1.1e-104 350.0 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Smg4_UPF3 PF03467.15 EPS32993.1 - 1.4e-42 145.6 2.8 1.5e-42 145.6 0.0 2.3 1 1 1 2 2 2 1 Smg-4/UPF3 family RRM_1 PF00076.22 EPS32993.1 - 1.5e-08 34.3 0.6 1.7e-06 27.8 0.1 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fungal_trans PF04082.18 EPS32994.1 - 1.9e-11 43.5 0.0 3.4e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS32994.1 - 2e-05 24.6 9.6 3.7e-05 23.7 9.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.19 EPS32995.1 - 1.1e-15 57.7 0.8 6.4e-15 55.3 0.8 2.2 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EPS32995.1 - 2.3e-08 34.1 0.5 5.8e-08 32.8 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EPS32995.1 - 4.9e-06 25.8 0.1 6.8e-06 25.4 0.1 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EPS32995.1 - 5.6e-06 25.8 0.4 1.1e-05 24.9 0.4 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EPS32995.1 - 9.6e-06 25.4 5.9 1.6e-05 24.6 4.2 1.9 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EPS32995.1 - 0.00036 19.7 3.3 0.00055 19.1 2.8 1.5 1 1 1 2 2 2 1 FAD binding domain Amino_oxidase PF01593.24 EPS32995.1 - 0.00046 19.6 0.8 0.012 14.9 0.1 2.2 1 1 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 EPS32995.1 - 0.00057 20.4 1.5 0.0016 19.0 1.5 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EPS32995.1 - 0.0011 18.4 0.2 0.0016 17.9 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 EPS32995.1 - 0.0054 15.9 1.7 0.0093 15.1 1.7 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Rossmann-like PF10727.9 EPS32995.1 - 0.0057 16.5 0.4 0.012 15.4 0.4 1.5 1 0 0 1 1 1 1 Rossmann-like domain Trp_halogenase PF04820.14 EPS32995.1 - 0.011 14.7 2.5 0.73 8.6 1.5 2.9 3 0 0 3 3 3 0 Tryptophan halogenase HI0933_like PF03486.14 EPS32995.1 - 0.03 13.0 1.6 0.044 12.5 1.6 1.2 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.18 EPS32995.1 - 0.047 13.6 1.4 0.077 12.9 1.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 EPS32995.1 - 0.13 11.5 0.5 0.29 10.3 0.5 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.15 EPS32995.1 - 0.17 12.0 0.2 0.34 11.1 0.2 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase AlaDh_PNT_C PF01262.21 EPS32995.1 - 0.18 11.1 1.0 0.3 10.4 1.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.23 EPS32995.1 - 0.2 11.6 0.4 0.35 10.8 0.4 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 EPS32995.1 - 0.69 9.5 2.3 4 7.1 1.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Aldedh PF00171.22 EPS32996.1 - 7.3e-185 614.9 0.9 8.2e-185 614.7 0.9 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AtuA PF07287.11 EPS32998.1 - 3e-122 407.7 0.0 3.6e-122 407.5 0.0 1.0 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA Mre11_DNA_bind PF04152.14 EPS32999.1 - 7.7e-58 195.5 0.3 7.7e-58 195.5 0.3 1.7 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 EPS32999.1 - 1.2e-14 55.3 0.8 2.3e-14 54.4 0.8 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EPS32999.1 - 0.0006 20.0 0.1 0.004 17.4 0.1 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain F-box-like PF12937.7 EPS33000.1 - 6.1e-11 42.0 0.3 1.4e-10 40.9 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EPS33000.1 - 3.8e-09 36.2 0.2 2e-08 33.9 0.1 2.1 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 EPS33000.1 - 0.0092 15.9 0.1 0.024 14.5 0.1 1.7 1 0 0 1 1 1 1 F-box UIM PF02809.20 EPS33000.1 - 1.1 9.3 11.1 2.6 8.2 0.3 3.2 3 0 0 3 3 3 0 Ubiquitin interaction motif Glyco_hydro_72 PF03198.14 EPS33001.1 - 1.2e-128 428.8 0.8 1.5e-128 428.5 0.8 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 EPS33001.1 - 0.085 12.3 0.4 7.5 5.9 0.1 2.3 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) MAS20 PF02064.15 EPS33002.1 - 2.7e-45 153.6 0.9 3.2e-45 153.4 0.9 1.0 1 0 0 1 1 1 1 MAS20 protein import receptor LapA_dom PF06305.11 EPS33002.1 - 0.081 12.8 0.0 0.19 11.5 0.0 1.6 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Exo84_C PF16528.5 EPS33003.1 - 1.1e-66 224.6 1.3 3.5e-66 222.9 0.0 2.0 2 0 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 EPS33003.1 - 1.4e-18 66.7 3.5 1.4e-18 66.7 3.5 1.7 2 0 0 2 2 2 1 Vps51/Vps67 DUF2594 PF10769.9 EPS33003.1 - 0.086 12.9 0.1 0.22 11.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2594) DUF2130 PF09903.9 EPS33003.1 - 0.16 11.2 2.6 3 7.1 1.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2130) COG2 PF06148.11 EPS33003.1 - 0.19 11.8 1.8 0.24 11.5 0.4 1.9 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 SKA2 PF16740.5 EPS33003.1 - 0.48 10.2 4.7 0.2 11.4 1.9 1.8 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 BST2 PF16716.5 EPS33003.1 - 1.6 9.4 7.0 16 6.1 3.8 2.7 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 HIP1_clath_bdg PF16515.5 EPS33003.1 - 3.3 8.4 7.9 1.5 9.5 4.0 2.2 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ABC_tran PF00005.27 EPS33004.1 - 2e-25 89.9 0.0 3e-12 47.2 0.0 3.6 4 1 0 4 4 3 2 ABC transporter AAA_21 PF13304.6 EPS33004.1 - 3.9e-11 43.3 9.9 0.00024 21.0 0.1 3.3 2 1 1 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EPS33004.1 - 9.1e-06 25.8 0.0 0.096 12.9 0.0 2.5 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 EPS33004.1 - 0.016 14.9 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 EPS33004.1 - 0.017 14.3 0.1 0.96 8.6 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_23 PF13476.6 EPS33004.1 - 0.047 14.2 0.6 0.1 13.1 0.6 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EPS33004.1 - 0.056 13.7 0.1 2.3 8.5 0.0 2.9 2 1 1 3 3 3 0 AAA domain DUF3584 PF12128.8 EPS33004.1 - 0.09 10.3 0.2 0.13 9.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) SMC_N PF02463.19 EPS33004.1 - 0.099 12.1 0.0 3.1 7.2 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain NACHT PF05729.12 EPS33004.1 - 0.11 12.4 0.7 0.51 10.2 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.6 EPS33004.1 - 0.13 12.5 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ploopntkinase1 PF18748.1 EPS33004.1 - 0.14 11.6 0.0 0.59 9.6 0.0 1.8 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 AMP-binding PF00501.28 EPS33005.1 - 1.2e-73 248.1 0.0 1.7e-73 247.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EPS33005.1 - 8.3e-11 42.7 0.4 1.7e-10 41.8 0.4 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CPSase_L_D2 PF02786.17 EPS33006.1 - 9.1e-114 378.2 0.2 1e-83 280.0 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 EPS33006.1 - 2e-47 160.2 0.0 4.5e-47 159.1 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.28 EPS33006.1 - 2e-47 161.4 0.0 7.9e-47 159.5 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase class-I OTCace_N PF02729.21 EPS33006.1 - 2.7e-44 150.8 0.0 6e-44 149.7 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.19 EPS33006.1 - 4e-38 130.5 0.0 8.6e-38 129.4 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 EPS33006.1 - 4.6e-30 104.8 0.0 1.1e-29 103.5 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 EPS33006.1 - 6.5e-20 71.1 0.0 2.7e-19 69.2 0.0 2.2 2 0 0 2 2 1 1 MGS-like domain Dala_Dala_lig_C PF07478.13 EPS33006.1 - 6.2e-18 65.1 0.4 2e-08 34.0 0.1 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EPS33006.1 - 1.9e-14 53.6 0.1 9.1e-08 31.9 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 EPS33006.1 - 3.3e-09 36.6 0.1 0.00063 19.5 0.0 2.9 3 0 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 EPS33006.1 - 1.4e-05 25.2 0.5 0.11 12.5 0.0 2.9 3 0 0 3 3 3 2 ATP-grasp domain Peptidase_C26 PF07722.13 EPS33006.1 - 0.0001 22.1 0.2 0.0083 15.9 0.2 2.5 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 EPS33006.1 - 0.004 17.0 0.0 1.1 9.1 0.0 3.6 3 0 0 3 3 3 1 DJ-1/PfpI family RimK PF08443.11 EPS33006.1 - 0.0072 15.9 0.0 2.3 7.8 0.0 2.6 2 0 0 2 2 2 1 RimK-like ATP-grasp domain Ion_trans PF00520.31 EPS33007.1 - 3.3e-09 36.3 27.2 5e-09 35.7 27.2 1.2 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 EPS33007.1 - 0.0041 15.8 21.8 0.18 10.4 21.8 2.2 1 1 0 1 1 1 1 Polycystin cation channel Synaptobrevin PF00957.21 EPS33009.1 - 1.1e-31 108.5 0.0 1.4e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EPS33009.1 - 1.6e-28 98.5 0.0 2.7e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain FOXP-CC PF16159.5 EPS33010.1 - 0.3 11.8 5.3 0.62 10.7 0.3 2.4 1 1 1 2 2 2 0 FOXP coiled-coil domain Ost4 PF10215.9 EPS33011.1 - 4.2e-19 68.1 1.2 6e-19 67.6 1.2 1.2 1 0 0 1 1 1 1 Oligosaccaryltransferase Zn_clus PF00172.18 EPS33012.1 - 1.2e-09 38.1 6.0 2e-09 37.4 6.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPS33012.1 - 4.8e-09 35.6 0.0 8.5e-09 34.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain TPR_10 PF13374.6 EPS33012.1 - 0.17 11.8 0.4 4.9 7.2 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat RabGAP-TBC PF00566.18 EPS33013.1 - 3.4e-43 147.8 0.0 1.6e-41 142.3 0.0 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain ComZ PF10815.8 EPS33013.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 ComZ adh_short_C2 PF13561.6 EPS33014.1 - 1.8e-54 184.8 2.4 2.2e-54 184.5 2.4 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPS33014.1 - 1e-46 158.9 1.2 1.3e-46 158.6 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPS33014.1 - 1.9e-08 34.5 0.8 5.1e-08 33.0 0.8 1.7 1 1 0 1 1 1 1 KR domain DENN PF02141.21 EPS33015.1 - 2.5e-40 138.4 0.1 4.9e-40 137.5 0.1 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.18 EPS33015.1 - 4.3e-06 27.4 0.1 2.5e-05 24.9 0.0 2.4 2 0 0 2 2 2 1 uDENN domain Elongin_A PF06881.11 EPS33015.1 - 0.0054 17.2 4.6 0.025 15.1 4.6 2.1 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Cnn_1N PF07989.11 EPS33015.1 - 1 9.6 12.3 0.1 12.8 2.7 3.0 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 ATG16 PF08614.11 EPS33015.1 - 2.4 8.4 23.9 0.049 13.9 6.3 3.2 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) DUF3450 PF11932.8 EPS33015.1 - 3.7 6.8 14.5 1.3 8.2 3.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) GldM_N PF12081.8 EPS33015.1 - 4 7.5 12.3 1.3 9.1 5.7 2.8 1 1 2 3 3 3 0 GldM N-terminal domain Fib_alpha PF08702.10 EPS33015.1 - 7.4 6.8 12.9 1.8 8.7 2.2 2.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Pkinase PF00069.25 EPS33016.1 - 1.3e-23 83.8 0.0 1.9e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 EPS33016.1 - 1.1e-09 37.7 1.2 0.81 10.1 0.1 6.4 6 0 0 6 6 6 3 HEAT repeat WD40 PF00400.32 EPS33016.1 - 5e-08 33.5 12.5 5.5e-07 30.2 0.1 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat Pkinase_Tyr PF07714.17 EPS33016.1 - 5.5e-05 22.6 0.0 9.4e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Cnd1 PF12717.7 EPS33016.1 - 0.022 14.8 0.6 0.088 12.9 0.0 2.2 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Ge1_WD40 PF16529.5 EPS33016.1 - 0.036 13.0 0.0 0.55 9.1 0.0 2.3 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Tti2 PF10521.9 EPS33016.1 - 0.075 12.6 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Tti2 family M11L PF11099.8 EPS33016.1 - 0.077 13.3 0.8 18 5.5 0.0 2.7 3 0 0 3 3 3 0 Apoptosis regulator M11L like RTP1_C1 PF10363.9 EPS33016.1 - 0.16 12.2 0.3 3.1 8.0 0.0 2.6 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 zf-C2H2 PF00096.26 EPS33019.1 - 1.4e-09 37.8 19.1 0.00058 20.2 0.1 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EPS33019.1 - 0.00085 19.3 10.2 0.14 12.2 0.0 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 EPS33019.1 - 0.0057 17.4 25.2 0.014 16.2 0.0 4.0 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EPS33019.1 - 0.025 15.0 17.7 0.27 11.7 0.9 3.6 3 0 0 3 3 3 0 Zinc-finger double domain zf-Di19 PF05605.12 EPS33019.1 - 0.047 14.0 0.7 0.047 14.0 0.7 2.5 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 EPS33019.1 - 0.32 11.3 0.1 0.32 11.3 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Endonuclease_7 PF02945.15 EPS33019.1 - 0.59 10.1 11.5 0.11 12.5 6.4 2.0 1 1 1 2 2 2 0 Recombination endonuclease VII zf-met PF12874.7 EPS33019.1 - 5.7 7.5 8.7 4.1 7.9 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type NUDIX PF00293.28 EPS33021.1 - 6.2e-27 94.2 0.0 8.7e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain tRNA-synt_2e PF02091.15 EPS33021.1 - 0.18 11.0 0.0 0.36 10.0 0.0 1.4 1 0 0 1 1 1 0 Glycyl-tRNA synthetase alpha subunit DUF202 PF02656.15 EPS33022.1 - 6.4e-18 65.0 4.7 1.1e-17 64.2 0.8 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF2976 PF11190.8 EPS33022.1 - 0.026 14.3 1.4 0.044 13.6 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Holin_2-3 PF13272.6 EPS33022.1 - 0.051 13.9 0.1 0.086 13.1 0.1 1.5 1 1 0 1 1 1 0 Putative 2/3 transmembrane domain holin Tetraspanin PF00335.20 EPS33022.1 - 0.059 13.1 1.5 1.9 8.1 2.2 2.0 2 0 0 2 2 2 0 Tetraspanin family S_4TM PF18159.1 EPS33022.1 - 0.091 12.0 0.2 0.12 11.7 0.2 1.1 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain DUF716 PF04819.12 EPS33022.1 - 0.15 11.7 2.7 0.11 12.1 1.4 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF716) MatE PF01554.18 EPS33023.1 - 5.9e-54 182.1 24.7 1.2e-33 116.1 7.7 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 EPS33023.1 - 0.00013 22.0 6.9 0.00013 22.0 6.9 3.6 3 2 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain DUF4750 PF15938.5 EPS33023.1 - 4.3 7.1 7.7 15 5.4 0.9 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4750) RPA_C PF08784.11 EPS33024.1 - 1.3e-22 80.4 0.1 3.8e-22 78.9 0.1 1.8 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 EPS33024.1 - 0.00015 21.7 0.7 0.00034 20.5 0.7 1.6 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain DEAD PF00270.29 EPS33025.1 - 1.9e-48 164.5 0.0 6.8e-48 162.7 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPS33025.1 - 2.3e-22 79.4 0.0 7.8e-22 77.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 EPS33025.1 - 2.2e-21 75.9 3.6 2.2e-21 75.9 3.6 2.4 2 0 0 2 2 2 1 DBP10CT (NUC160) domain Zn_clus PF00172.18 EPS33028.1 - 0.00055 20.0 9.1 0.00089 19.3 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFB6 PF17110.5 EPS33029.1 - 0.049 13.4 0.4 0.054 13.2 0.4 1.0 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH NOA36 PF06524.12 EPS33029.1 - 0.38 10.0 4.6 0.34 10.2 4.6 1.1 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 EPS33029.1 - 0.61 10.5 10.2 0.69 10.3 10.2 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DNA_pol_phi PF04931.13 EPS33029.1 - 6.3 4.8 7.4 6.4 4.7 7.4 1.0 1 0 0 1 1 1 0 DNA polymerase phi AA_permease PF00324.21 EPS33030.1 - 3.4e-128 428.3 40.3 3.8e-128 428.1 40.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EPS33030.1 - 1.8e-45 155.6 46.2 2.1e-45 155.4 46.2 1.0 1 0 0 1 1 1 1 Amino acid permease PrgI PF12666.7 EPS33030.1 - 0.063 14.0 1.0 0.063 14.0 1.0 4.1 5 0 0 5 5 5 0 PrgI family protein DEAD PF00270.29 EPS33031.1 - 3.6e-47 160.4 0.0 6.2e-47 159.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPS33031.1 - 1.2e-23 83.6 0.0 4.5e-23 81.7 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EPS33031.1 - 8.8e-21 73.9 0.0 2.3e-20 72.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EPS33031.1 - 1.8e-09 37.8 0.0 7.3e-09 35.9 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 EPS33031.1 - 0.093 12.7 0.0 0.36 10.8 0.0 1.9 1 1 0 1 1 1 0 Flavivirus DEAD domain DnaJ PF00226.31 EPS33032.1 - 4.4e-14 52.4 4.7 4.6e-14 52.3 0.8 2.7 3 0 0 3 3 3 1 DnaJ domain HSP20 PF00011.21 EPS33032.1 - 0.0034 17.5 0.7 4 7.6 0.0 2.6 2 1 0 2 2 2 2 Hsp20/alpha crystallin family FKBP26_C PF18046.1 EPS33032.1 - 0.067 13.3 0.1 0.84 9.8 0.0 2.2 2 0 0 2 2 2 0 FKBP26_C-terminal PAPS_reduct PF01507.19 EPS33033.1 - 1.5e-23 83.8 0.0 2.4e-22 79.8 0.0 2.5 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family RRM_1 PF00076.22 EPS33034.1 - 6.4e-26 90.0 0.0 1.7e-13 50.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAD_binding_2 PF03446.15 EPS33035.1 - 1.1e-33 116.6 0.4 1.9e-33 115.9 0.4 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EPS33035.1 - 1.1e-28 100.0 0.0 2.8e-28 98.6 0.0 1.7 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 EPS33035.1 - 0.00024 21.6 0.1 0.0005 20.6 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 EPS33035.1 - 0.0078 15.6 0.2 0.14 11.5 0.2 2.2 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain OCD_Mu_crystall PF02423.15 EPS33035.1 - 0.026 13.5 0.2 0.045 12.7 0.2 1.4 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family TGS PF02824.21 EPS33035.1 - 0.048 13.7 0.0 0.16 12.0 0.0 1.9 1 1 0 1 1 1 0 TGS domain Shikimate_DH PF01488.20 EPS33035.1 - 0.09 12.8 0.2 0.22 11.6 0.2 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Tim17 PF02466.19 EPS33035.1 - 0.093 13.1 0.3 0.19 12.1 0.3 1.5 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family PQQ PF01011.21 EPS33036.1 - 0.15 12.0 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 PQQ enzyme repeat MOR2-PAG1_N PF14222.6 EPS33037.1 - 9.6e-205 681.7 0.0 2e-204 680.6 0.0 1.6 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 EPS33037.1 - 8e-89 297.8 0.0 8e-89 297.8 0.0 2.5 3 0 0 3 3 3 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 EPS33037.1 - 1.6e-32 112.2 15.8 3.7e-18 64.6 8.3 3.8 1 1 0 2 2 2 2 Cell morphogenesis central region FAD_binding_1 PF00667.20 EPS33038.1 - 1e-63 214.9 0.0 1.4e-63 214.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EPS33038.1 - 1.3e-34 119.4 2.2 2.4e-34 118.6 2.2 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EPS33038.1 - 2.8e-20 73.0 0.0 2.1e-19 70.2 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Shikimate_DH PF01488.20 EPS33038.1 - 0.058 13.5 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Flavodoxin_5 PF12724.7 EPS33038.1 - 0.16 12.2 0.1 0.52 10.5 0.0 1.9 2 0 0 2 2 2 0 Flavodoxin domain MMS1_N PF10433.9 EPS33039.1 - 6.4e-128 427.5 0.0 1.4e-127 426.3 0.0 1.5 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EPS33039.1 - 3.1e-73 246.9 0.9 1.4e-71 241.5 0.2 3.0 3 0 0 3 3 3 1 CPSF A subunit region PGA2 PF07543.12 EPS33040.1 - 1.1e-43 148.5 4.2 1.4e-43 148.2 4.2 1.1 1 0 0 1 1 1 1 Protein trafficking PGA2 FmdE PF02663.14 EPS33040.1 - 0.071 13.2 3.4 3.7 7.6 0.4 2.2 2 0 0 2 2 2 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Zip PF02535.22 EPS33040.1 - 0.25 10.5 0.1 0.28 10.4 0.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CENP-S PF15630.6 EPS33041.1 - 1.3e-35 121.6 0.0 1.6e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 EPS33041.1 - 1.2e-09 38.2 0.0 1.5e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 EPS33041.1 - 2.7e-05 24.1 0.0 4.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated SUR7 PF06687.12 EPS33043.1 - 0.023 14.3 0.9 0.023 14.3 0.9 2.7 1 1 1 2 2 2 0 SUR7/PalI family MARVEL PF01284.23 EPS33043.1 - 0.58 10.2 18.2 2 8.4 18.3 1.8 1 1 1 2 2 2 0 Membrane-associating domain DUF805 PF05656.14 EPS33043.1 - 1.9 8.9 5.1 17 5.9 5.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF805) EphA2_TM PF14575.6 EPS33043.1 - 2.2 9.2 4.9 3.8 8.5 0.0 2.7 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Pkinase PF00069.25 EPS33045.1 - 7.8e-30 104.1 0.0 1.2e-28 100.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS33045.1 - 8.2e-13 48.2 0.0 3.7e-05 23.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase UvdE PF03851.14 EPS33046.1 - 3.3e-111 371.0 0.0 4.2e-111 370.6 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE BCMA-Tall_bind PF09257.10 EPS33046.1 - 0.18 12.0 2.5 0.17 12.0 0.6 1.9 2 0 0 2 2 2 0 BCMA, TALL-1 binding DUF2183 PF09949.9 EPS33047.1 - 9.4e-33 112.5 0.0 3.2e-32 110.8 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.13 EPS33047.1 - 0.049 13.1 0.0 0.08 12.4 0.0 1.2 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) RPAP1_N PF08621.10 EPS33047.1 - 0.087 12.6 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 RPAP1-like, N-terminal Acyl-CoA_dh_1 PF00441.24 EPS33048.1 - 2.4e-31 109.0 1.4 2.4e-31 109.0 1.4 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.28 EPS33048.1 - 2.2e-21 75.8 0.0 5e-21 74.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.19 EPS33048.1 - 7.9e-19 67.7 0.2 1.4e-18 66.9 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EPS33048.1 - 5.6e-08 33.4 0.5 1.5e-07 32.1 0.1 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EPS33048.1 - 1.3e-05 25.4 0.0 3.6e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain PI31_Prot_N PF11566.8 EPS33049.1 - 3.1e-52 176.7 0.0 3.8e-52 176.4 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 EPS33049.1 - 7.7e-16 59.0 18.1 7.7e-16 59.0 18.1 2.8 3 0 0 3 3 3 1 PI31 proteasome regulator NmrA PF05368.13 EPS33050.1 - 6.5e-36 124.1 0.3 8.9e-36 123.6 0.3 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPS33050.1 - 1.4e-16 60.9 0.0 2e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EPS33050.1 - 2.7e-11 43.4 0.0 1.3e-10 41.2 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EPS33050.1 - 4.3e-07 29.2 0.0 6.2e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 EPS33050.1 - 7.7e-06 25.5 0.1 1.5e-05 24.5 0.1 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPS33050.1 - 2.4e-05 24.3 0.1 6.7e-05 22.9 0.1 1.7 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EPS33050.1 - 0.00051 19.3 0.1 0.0026 16.9 0.1 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.17 EPS33050.1 - 0.00059 20.4 0.1 0.01 16.4 0.1 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_4 PF07993.12 EPS33050.1 - 0.0019 17.4 0.0 0.0065 15.7 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein GDP_Man_Dehyd PF16363.5 EPS33050.1 - 0.0021 17.5 0.0 0.0034 16.8 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 EPS33050.1 - 0.0038 17.5 0.1 0.006 16.8 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain DapB_N PF01113.20 EPS33050.1 - 0.0062 16.6 0.0 0.018 15.2 0.0 1.8 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 EPS33050.1 - 0.022 15.2 0.0 0.097 13.1 0.0 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Dehalogenase PF13486.6 EPS33050.1 - 0.038 13.4 0.0 1 8.7 0.0 2.1 2 0 0 2 2 2 0 Reductive dehalogenase subunit RmlD_sub_bind PF04321.17 EPS33050.1 - 0.057 12.5 0.0 0.55 9.3 0.0 2.3 3 0 0 3 3 3 0 RmlD substrate binding domain Metallophos PF00149.28 EPS33051.1 - 5.9e-38 131.4 0.4 9.7e-38 130.7 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EPS33051.1 - 0.024 15.0 0.0 0.048 14.1 0.0 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain DUF3112 PF11309.8 EPS33052.1 - 2.3e-11 43.6 11.0 7.8e-08 32.0 0.1 2.5 2 1 1 3 3 3 2 Protein of unknown function (DUF3112) MIG-14_Wnt-bd PF06664.12 EPS33052.1 - 0.12 11.6 11.7 0.014 14.6 6.6 1.9 1 1 1 2 2 2 0 Wnt-binding factor required for Wnt secretion MFS_1 PF07690.16 EPS33054.1 - 7.8e-55 186.2 37.4 3.1e-50 171.1 15.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EPS33054.1 - 5.7e-12 44.7 2.5 1.7e-08 33.2 0.4 3.4 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 EPS33054.1 - 0.00021 20.3 8.6 0.00021 20.3 8.6 3.1 2 2 1 3 3 3 1 MFS_1 like family MFS_3 PF05977.13 EPS33054.1 - 0.0014 17.1 8.1 0.0014 17.1 8.1 2.2 2 1 0 2 2 2 1 Transmembrane secretion effector PTR2 PF00854.21 EPS33054.1 - 0.013 14.4 0.4 0.013 14.4 0.4 2.3 2 0 0 2 2 2 0 POT family DUF2754 PF10953.8 EPS33054.1 - 1.1 9.5 0.0 1.1 9.5 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2754) HAD_2 PF13419.6 EPS33055.1 - 1.2e-14 54.7 0.0 1.9e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EPS33055.1 - 1e-07 32.5 0.0 9.9e-06 26.0 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EPS33055.1 - 0.0069 16.4 0.0 0.017 15.1 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like NT5C PF06941.12 EPS33055.1 - 0.012 15.5 0.0 0.11 12.4 0.0 2.0 1 1 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) WD40 PF00400.32 EPS33056.1 - 3.3e-06 27.7 7.6 5.2 8.1 0.0 6.7 6 1 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS33056.1 - 0.0013 19.0 0.0 3 8.2 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 EPS33056.1 - 0.0056 16.0 0.0 0.011 15.0 0.0 1.5 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller Nucleoporin_FG PF13634.6 EPS33057.1 - 4.6e-11 43.4 85.7 2.4e-09 37.9 39.4 3.6 1 1 2 3 3 3 3 Nucleoporin FG repeat region DUF1664 PF07889.12 EPS33057.1 - 0.084 12.9 0.6 0.65 10.1 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Cpn10 PF00166.21 EPS33058.1 - 1.2e-28 99.0 0.0 1.3e-28 98.9 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Fip1 PF05182.13 EPS33059.1 - 4.9e-20 70.8 2.0 1e-19 69.7 2.0 1.5 1 0 0 1 1 1 1 Fip1 motif SPX PF03105.19 EPS33059.1 - 0.37 10.7 1.5 0.47 10.3 1.5 1.1 1 0 0 1 1 1 0 SPX domain SOG2 PF10428.9 EPS33059.1 - 9.7 5.3 7.2 14 4.8 7.2 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein XAP5 PF04921.14 EPS33060.1 - 1.2e-86 290.6 0.0 1.7e-86 290.1 0.0 1.2 1 0 0 1 1 1 1 XAP5, circadian clock regulator DUF4604 PF15377.6 EPS33060.1 - 0.0035 17.8 5.7 0.0035 17.8 5.7 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4604) zf-RING_5 PF14634.6 EPS33061.1 - 1.4e-08 34.5 8.1 2.6e-08 33.7 8.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EPS33061.1 - 7.2e-05 22.6 6.3 0.00014 21.6 6.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EPS33061.1 - 0.0002 21.6 5.5 0.00043 20.5 5.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EPS33061.1 - 0.0036 17.1 5.7 0.0078 16.0 5.0 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPS33061.1 - 0.01 15.8 2.0 0.01 15.8 2.0 2.1 1 1 1 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EPS33061.1 - 0.012 15.8 4.0 0.03 14.5 4.0 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EPS33061.1 - 0.012 15.4 10.3 0.024 14.5 10.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Spc24 PF08286.11 EPS33061.1 - 0.013 15.8 3.5 0.021 15.0 3.5 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 zf-C3HC4 PF00097.25 EPS33061.1 - 0.016 15.0 7.7 0.04 13.8 7.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4472 PF14739.6 EPS33061.1 - 0.022 15.5 6.3 0.043 14.5 6.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) zf-RING_4 PF14570.6 EPS33061.1 - 0.11 12.4 2.8 0.21 11.4 2.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Mod_r PF07200.13 EPS33061.1 - 0.13 12.4 8.5 0.22 11.6 8.5 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein zinc_ribbon_9 PF14369.6 EPS33061.1 - 0.13 12.5 1.3 0.3 11.4 1.3 1.6 1 0 0 1 1 1 0 zinc-ribbon CENP-H PF05837.12 EPS33061.1 - 0.2 12.1 6.5 0.36 11.2 6.5 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) ZapB PF06005.12 EPS33061.1 - 0.39 11.2 5.0 0.83 10.1 5.0 1.6 1 1 0 1 1 1 0 Cell division protein ZapB Phage_Mu_Gam PF07352.12 EPS33061.1 - 0.4 10.6 4.2 0.6 10.0 4.2 1.2 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein OmpH PF03938.14 EPS33061.1 - 0.44 10.9 9.2 0.66 10.3 9.2 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) zf-rbx1 PF12678.7 EPS33061.1 - 0.45 10.9 5.7 1.3 9.4 5.7 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_6 PF14835.6 EPS33061.1 - 0.52 10.2 5.9 1.2 9.1 5.9 1.6 1 1 0 1 1 1 0 zf-RING of BARD1-type protein YabA PF06156.13 EPS33061.1 - 0.63 10.7 4.9 1.7 9.4 4.8 1.7 1 1 0 1 1 1 0 Initiation control protein YabA DZR PF12773.7 EPS33061.1 - 0.71 9.9 7.0 2.8 8.0 7.0 2.0 1 1 0 1 1 1 0 Double zinc ribbon zf-MIZ PF02891.20 EPS33061.1 - 0.83 9.5 5.8 1.8 8.4 5.8 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger RTA1 PF04479.13 EPS33062.1 - 7.8e-56 188.9 8.4 1.2e-55 188.4 8.4 1.2 1 0 0 1 1 1 1 RTA1 like protein Fungal_trans_2 PF11951.8 EPS33063.1 - 5.6e-40 137.3 2.9 6.6e-40 137.1 2.9 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS33063.1 - 7.9e-06 25.9 8.9 1.6e-05 24.9 8.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cys_Met_Meta_PP PF01053.20 EPS33064.1 - 2.3e-59 200.8 0.0 6e-59 199.5 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EPS33064.1 - 0.0026 17.0 0.0 0.0044 16.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EPS33064.1 - 0.025 13.5 0.0 0.1 11.5 0.0 1.9 2 0 0 2 2 2 0 Aminotransferase class-V TRI5 PF06330.11 EPS33065.1 - 1.4e-14 53.8 0.2 1.8e-14 53.4 0.2 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) DUF4891 PF16232.5 EPS33065.1 - 0.0043 17.6 0.0 0.0084 16.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4891) Con-6 PF10346.9 EPS33067.1 - 1.9e-39 133.4 9.7 7.9e-15 54.6 0.1 3.6 4 0 0 4 4 4 3 Conidiation protein 6 hnRNP_Q_AcD PF18360.1 EPS33067.1 - 0.085 12.8 1.1 7.7 6.6 0.1 2.2 2 0 0 2 2 2 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain SpoIIIAH PF12685.7 EPS33067.1 - 2.4 7.9 5.3 12 5.7 0.4 2.6 2 1 0 3 3 3 0 SpoIIIAH-like protein Sda PF08970.10 EPS33068.1 - 0.28 11.0 3.4 71 3.2 0.0 3.7 5 0 0 5 5 5 0 Sporulation inhibitor A DUF3328 PF11807.8 EPS33069.1 - 2.8e-28 99.2 0.0 3.3e-28 99.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) NAD_binding_4 PF07993.12 EPS33070.1 - 6.7e-31 107.4 0.0 1.1e-30 106.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EPS33070.1 - 2.8e-08 33.5 0.0 6.9e-08 32.2 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EPS33070.1 - 1.1e-06 28.9 0.0 2.1e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 EPS33070.1 - 0.11 11.5 0.0 13 4.7 0.0 3.0 3 0 0 3 3 3 0 3-beta hydroxysteroid dehydrogenase/isomerase family Aldo_ket_red PF00248.21 EPS33071.1 - 1.9e-41 142.2 0.0 4.4e-39 134.4 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Lipase_GDSL_2 PF13472.6 EPS33072.1 - 9.1e-18 65.3 1.1 1.6e-17 64.5 1.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EPS33072.1 - 1.2e-06 28.6 0.0 2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Sugar_tr PF00083.24 EPS33073.1 - 8.1e-72 242.5 19.5 9.5e-72 242.3 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS33073.1 - 1.5e-26 93.2 25.3 1.6e-18 66.7 8.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EPS33073.1 - 0.00029 19.4 3.5 0.00029 19.4 3.5 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_43 PF04616.14 EPS33074.1 - 2.9e-80 269.7 0.2 4e-80 269.2 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GH43_C2 PF17851.1 EPS33074.1 - 8.3e-11 42.0 0.0 1.9e-10 40.8 0.0 1.5 2 0 0 2 2 2 1 Beta xylosidase C-terminal Concanavalin A-like domain Ntox33 PF15533.6 EPS33074.1 - 0.072 13.6 0.1 0.52 10.8 0.1 2.2 2 0 0 2 2 2 0 Bacterial toxin 33 Glyco_hydro_3_C PF01915.22 EPS33075.1 - 1e-45 156.2 0.0 1.7e-45 155.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EPS33075.1 - 1.4e-36 126.5 0.0 2.5e-36 125.7 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain WSC PF01822.19 EPS33075.1 - 9.7e-16 57.7 3.9 1.9e-15 56.8 3.9 1.5 1 0 0 1 1 1 1 WSC domain BNR_2 PF13088.6 EPS33076.1 - 0.003 16.9 0.6 0.03 13.6 0.6 2.0 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.20 EPS33076.1 - 0.0079 16.0 9.5 0.21 11.7 0.6 3.8 3 0 0 3 3 3 2 BNR/Asp-box repeat Sortilin-Vps10 PF15902.5 EPS33076.1 - 0.037 12.8 2.6 0.67 8.7 0.3 2.7 2 1 0 3 3 3 0 Sortilin, neurotensin receptor 3, Acetyltransf_1 PF00583.25 EPS33077.1 - 5.4e-08 33.1 0.1 1e-07 32.2 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EPS33077.1 - 0.00034 20.5 0.0 0.00057 19.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EPS33077.1 - 0.00092 19.6 0.1 0.002 18.5 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 EPS33077.1 - 0.03 14.1 0.0 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_CG PF14542.6 EPS33077.1 - 0.11 12.7 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Pho86 PF11124.8 EPS33077.1 - 0.16 11.4 0.1 0.25 10.8 0.1 1.2 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 Sugar_tr PF00083.24 EPS33078.1 - 1.3e-47 162.8 18.6 6.2e-47 160.5 18.6 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS33078.1 - 1.3e-20 73.7 26.3 1.3e-20 73.7 26.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS33079.1 - 3.6e-10 39.3 5.0 4.6e-10 39.0 5.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Aa_trans PF01490.18 EPS33080.1 - 6.6e-55 186.5 37.3 7.5e-55 186.3 37.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CD99L2 PF12301.8 EPS33080.1 - 7.5 6.8 5.7 0.49 10.7 0.4 1.7 2 0 0 2 2 2 0 CD99 antigen like protein 2 DHDPS PF00701.22 EPS33082.1 - 7.9e-39 133.1 0.0 1e-38 132.7 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family MFS_1 PF07690.16 EPS33083.1 - 9.6e-38 130.0 40.9 9.6e-38 130.0 40.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Chitin_synth_1 PF01644.17 EPS33084.1 - 1.5e-69 233.1 0.0 2.2e-69 232.6 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EPS33084.1 - 1.2e-27 95.7 0.0 4.5e-27 93.8 0.0 2.0 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EPS33084.1 - 7.8e-21 74.3 0.1 9.2e-19 67.4 0.0 2.1 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EPS33084.1 - 1.4e-09 38.2 0.1 1.4e-09 38.2 0.1 2.8 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Cyclase PF04199.13 EPS33085.1 - 3.7e-16 59.6 0.0 5.1e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Fungal_trans PF04082.18 EPS33086.1 - 3.5e-16 59.0 0.2 7.9e-16 57.9 0.2 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS33086.1 - 2.2e-06 27.7 7.2 3.8e-06 26.9 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hydantoinase_B PF02538.14 EPS33087.1 - 2e-216 719.4 0.3 2.6e-216 719.0 0.3 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EPS33087.1 - 2.4e-101 338.8 0.0 4.2e-100 334.7 0.0 2.2 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EPS33087.1 - 2.2e-57 193.6 0.0 1.6e-54 184.3 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region His_Phos_1 PF00300.22 EPS33088.1 - 0.00057 19.6 0.8 1.7 8.3 0.0 3.8 4 0 0 4 4 4 2 Histidine phosphatase superfamily (branch 1) 5_nucleotid_C PF02872.18 EPS33089.1 - 4.3e-39 134.2 0.0 9e-39 133.2 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EPS33089.1 - 9.5e-05 23.0 0.2 0.00015 22.3 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PCI PF01399.27 EPS33090.1 - 0.11 13.0 0.0 9.8 6.7 0.0 2.9 3 0 0 3 3 3 0 PCI domain FMO-like PF00743.19 EPS33091.1 - 1.8e-23 82.8 0.0 5.5e-23 81.2 0.0 1.7 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EPS33091.1 - 1.6e-14 53.9 0.0 1.1e-10 41.3 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EPS33091.1 - 1.2e-12 47.7 0.6 2.5e-09 36.8 0.4 2.7 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EPS33091.1 - 6.4e-12 45.3 0.0 5.8e-09 35.6 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EPS33091.1 - 1.4e-06 28.5 1.1 6e-05 23.2 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EPS33091.1 - 1.5e-06 28.3 0.5 0.074 13.0 0.0 3.4 3 0 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.24 EPS33091.1 - 1.9e-05 24.4 0.6 0.0057 16.3 1.0 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EPS33091.1 - 2.5e-05 24.8 4.5 0.1 13.2 0.5 2.7 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EPS33091.1 - 2.8e-05 23.5 0.7 0.012 15.0 0.0 2.4 2 1 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 EPS33091.1 - 0.0002 21.4 0.0 0.91 9.6 0.0 2.9 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.18 EPS33091.1 - 0.0022 17.9 0.1 0.0035 17.2 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 EPS33091.1 - 0.0032 17.9 0.0 0.2 12.1 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.24 EPS33091.1 - 0.069 12.2 0.5 0.14 11.2 0.5 1.5 1 0 0 1 1 1 0 FAD binding domain SIS_2 PF13580.6 EPS33091.1 - 0.086 12.9 0.0 7.1 6.7 0.0 2.5 2 0 0 2 2 2 0 SIS domain HI0933_like PF03486.14 EPS33091.1 - 0.1 11.3 1.8 0.76 8.4 0.2 2.6 3 0 0 3 3 3 0 HI0933-like protein 2-Hacid_dh_C PF02826.19 EPS33091.1 - 0.19 11.1 0.0 8.9 5.6 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF2165 PF09933.9 EPS33092.1 - 0.023 14.7 0.1 0.039 14.0 0.1 1.3 1 0 0 1 1 1 0 Predicted small integral membrane protein (DUF2165) Sas10_Utp3 PF04000.15 EPS33093.1 - 1e-16 61.3 0.3 1e-16 61.3 0.3 2.5 2 1 0 2 2 2 1 Sas10/Utp3/C1D family DUF2151 PF10221.9 EPS33093.1 - 0.24 9.9 6.8 0.34 9.5 6.8 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator DUF913 PF06025.12 EPS33093.1 - 0.32 9.9 3.3 0.73 8.7 3.3 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) V_ATPase_I PF01496.19 EPS33093.1 - 4.4 5.1 4.0 6.4 4.6 4.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EMP70 PF02990.16 EPS33094.1 - 2.2e-202 673.4 0.5 2.9e-202 673.0 0.5 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 TOH_N PF12549.8 EPS33094.1 - 0.11 12.3 0.1 0.28 11.1 0.1 1.6 1 0 0 1 1 1 0 Tyrosine hydroxylase N terminal DUF3920 PF13058.6 EPS33094.1 - 0.18 12.0 0.0 0.35 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3920) EF-hand_1 PF00036.32 EPS33095.1 - 4.8e-26 88.3 11.7 3.6e-08 32.4 0.1 4.8 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 EPS33095.1 - 8.9e-26 87.6 4.8 3.5e-06 26.5 0.1 5.2 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 EPS33095.1 - 4.1e-24 84.8 7.8 9.2e-16 58.1 0.9 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EPS33095.1 - 2.1e-17 61.7 10.9 0.00016 21.0 0.1 4.7 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 EPS33095.1 - 7.1e-16 57.8 11.1 4.8e-06 26.3 1.1 4.1 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 EPS33095.1 - 4.3e-09 36.3 6.2 0.0026 17.7 0.1 3.8 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EPS33095.1 - 0.00013 22.2 0.7 0.022 15.1 0.1 3.2 2 1 1 3 3 3 2 EF-hand domain EF-hand_10 PF14788.6 EPS33095.1 - 0.0016 18.2 1.1 0.48 10.3 0.1 3.6 4 0 0 4 4 4 1 EF hand SPARC_Ca_bdg PF10591.9 EPS33095.1 - 0.014 15.7 2.2 2.1 8.7 0.3 3.1 2 2 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF1679 PF07914.11 EPS33095.1 - 0.032 13.1 0.4 2.5 6.8 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) Kinesin PF00225.23 EPS33096.1 - 2.1e-110 368.8 0.1 2.1e-110 368.8 0.1 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EPS33096.1 - 2.4e-24 86.0 0.0 8.8e-24 84.1 0.0 2.1 1 0 0 1 1 1 1 Microtubule binding YabA PF06156.13 EPS33096.1 - 0.0043 17.7 2.2 0.0043 17.7 2.2 5.9 3 2 3 6 6 6 2 Initiation control protein YabA APG6_N PF17675.1 EPS33096.1 - 0.013 16.0 8.7 0.013 16.0 8.7 4.7 2 2 2 4 4 4 0 Apg6 coiled-coil region DUF1398 PF07166.11 EPS33096.1 - 0.092 12.8 0.0 0.28 11.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1398) STPPase_N PF16891.5 EPS33096.1 - 0.15 12.6 1.2 33 5.0 0.2 3.1 2 0 0 2 2 2 0 Serine-threonine protein phosphatase N-terminal domain ATG_C PF09333.11 EPS33096.1 - 1.6 9.1 4.6 1.1 9.7 0.4 2.8 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain CENP-F_leu_zip PF10473.9 EPS33096.1 - 4 7.5 60.8 4.3 7.4 2.2 5.5 4 1 2 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CALCOCO1 PF07888.11 EPS33096.1 - 5.6 5.7 52.9 0.11 11.4 25.9 2.3 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF3763 PF12592.8 EPS33096.1 - 9.8 6.3 13.0 5.5 7.1 0.5 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3763) UQ_con PF00179.26 EPS33097.1 - 2.6e-51 172.9 0.0 3e-51 172.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EPS33097.1 - 0.0018 17.9 0.0 0.0021 17.8 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EPS33097.1 - 0.1 12.9 0.0 0.14 12.4 0.0 1.5 1 1 0 1 1 1 0 RWD domain Thiolase_N PF00108.23 EPS33098.1 - 2.5e-92 308.9 0.2 4.7e-92 308.0 0.2 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EPS33098.1 - 2.3e-38 130.6 1.4 2.3e-38 130.6 1.4 1.9 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EPS33098.1 - 9.4e-06 25.4 1.8 1.5e-05 24.8 0.4 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain TFIIIC_delta PF12657.7 EPS33099.1 - 2.2e-38 132.0 0.2 4.8e-38 130.9 0.2 1.6 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.7 EPS33099.1 - 2.4e-33 114.1 1.4 4.4e-33 113.3 1.4 1.4 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex DZR PF12773.7 EPS33099.1 - 2.6 8.2 4.3 4.4 7.4 0.4 2.4 2 0 0 2 2 2 0 Double zinc ribbon Glyco_trans_1_4 PF13692.6 EPS33100.1 - 2.5e-10 40.9 0.0 4.9e-08 33.5 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EPS33100.1 - 1.1e-05 25.1 0.0 0.00011 21.8 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EPS33100.1 - 6.5e-05 23.0 0.1 0.00015 21.8 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EPS33100.1 - 0.0087 16.5 1.0 0.065 13.7 0.0 2.5 1 1 2 3 3 3 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EPS33100.1 - 0.039 14.3 0.0 0.084 13.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 Cation_efflux PF01545.21 EPS33101.1 - 9.7e-47 159.3 12.4 9.7e-47 159.3 12.4 2.4 2 0 0 2 2 2 1 Cation efflux family NAD_binding_4 PF07993.12 EPS33102.1 - 1.3e-33 116.3 0.0 1.7e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 EPS33102.1 - 1.6e-05 24.2 0.0 2.2e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Zn_clus PF00172.18 EPS33103.1 - 1.4e-09 37.9 10.7 2.5e-09 37.1 10.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EPS33103.1 - 3.7e-05 22.7 0.2 6.2e-05 22.0 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.13 EPS33105.1 - 4.8e-72 241.9 2.8 6.8e-72 241.4 2.8 1.2 1 0 0 1 1 1 1 RTA1 like protein PhrC_PhrF PF11131.8 EPS33105.1 - 0.047 13.3 2.6 0.1 12.2 0.4 2.4 2 0 0 2 2 2 0 Rap-phr extracellular signalling UQ_con PF00179.26 EPS33106.1 - 3e-44 150.1 0.0 3.4e-44 149.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Amino_oxidase PF01593.24 EPS33108.1 - 1.3e-27 97.2 0.0 2e-27 96.6 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EPS33108.1 - 8.4e-15 54.8 0.0 2.3e-14 53.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EPS33108.1 - 4.6e-12 46.2 0.2 1.2e-05 25.1 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPS33108.1 - 3.7e-10 39.5 0.0 2.3e-07 30.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EPS33108.1 - 8.1e-08 31.4 0.2 0.00026 19.8 0.8 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 EPS33108.1 - 1.7e-06 27.7 0.0 2.5e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EPS33108.1 - 2.1e-06 28.2 1.0 0.012 16.2 0.8 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EPS33108.1 - 1e-05 24.8 6.6 3.3e-05 23.2 4.1 2.4 3 0 0 3 3 3 1 FAD binding domain GDI PF00996.18 EPS33108.1 - 0.00034 19.2 0.0 0.008 14.7 0.0 2.2 2 0 0 2 2 2 1 GDP dissociation inhibitor NAD_binding_9 PF13454.6 EPS33108.1 - 0.00069 19.6 1.3 0.099 12.6 0.2 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EPS33108.1 - 0.0013 18.0 1.5 0.0023 17.2 1.5 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EPS33108.1 - 0.0014 18.0 0.3 0.0064 15.8 0.3 2.1 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.22 EPS33108.1 - 0.0022 17.1 0.0 0.0047 16.1 0.0 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 EPS33108.1 - 0.0044 16.3 0.7 0.0077 15.5 0.7 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 EPS33108.1 - 0.038 13.0 0.1 0.08 12.0 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.14 EPS33108.1 - 0.048 12.5 3.3 3.3 6.4 1.7 2.3 2 0 0 2 2 2 0 Tryptophan halogenase ApbA PF02558.16 EPS33108.1 - 0.065 12.9 1.3 0.12 12.0 1.3 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.18 EPS33108.1 - 0.14 12.4 0.1 0.28 11.5 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.6 EPS33108.1 - 0.16 12.4 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding adh_short PF00106.25 EPS33108.1 - 0.19 11.1 0.8 0.32 10.4 0.8 1.3 1 0 0 1 1 1 0 short chain dehydrogenase 3HCDH_N PF02737.18 EPS33108.1 - 0.3 11.0 0.9 0.5 10.2 0.9 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SQS_PSY PF00494.19 EPS33109.1 - 7e-52 176.5 0.1 9e-52 176.2 0.1 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Amino_oxidase PF01593.24 EPS33110.1 - 5.6e-37 128.1 0.0 6.9e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EPS33110.1 - 9e-14 51.5 0.1 2.4e-13 50.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EPS33110.1 - 4.1e-10 39.8 0.0 4.5e-09 36.3 0.0 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPS33110.1 - 5.6e-09 35.6 0.0 2e-07 30.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EPS33110.1 - 4.8e-07 28.8 0.6 0.00098 17.9 0.9 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 EPS33110.1 - 7.4e-06 25.6 0.0 1.2e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EPS33110.1 - 1.6e-05 24.2 1.8 3.2e-05 23.2 1.1 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.27 EPS33110.1 - 0.00016 22.2 0.2 0.016 15.8 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.18 EPS33110.1 - 0.0029 16.2 0.0 0.15 10.5 0.0 2.1 2 0 0 2 2 2 1 GDP dissociation inhibitor AlaDh_PNT_C PF01262.21 EPS33110.1 - 0.0042 16.4 0.2 0.0076 15.6 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EPS33110.1 - 0.006 15.7 3.3 0.0067 15.6 1.2 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_9 PF13454.6 EPS33110.1 - 0.0067 16.4 0.3 0.19 11.7 0.1 2.6 3 0 0 3 3 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EPS33110.1 - 0.041 13.1 0.4 0.08 12.2 0.4 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EPS33110.1 - 0.046 12.9 0.1 0.11 11.7 0.1 1.6 1 0 0 1 1 1 0 Thi4 family 2-Hacid_dh_C PF02826.19 EPS33110.1 - 0.052 12.9 0.2 0.63 9.4 0.2 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 EPS33110.1 - 0.066 13.1 0.2 0.19 11.6 0.2 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.12 EPS33110.1 - 0.068 12.7 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain FMO-like PF00743.19 EPS33110.1 - 0.1 11.0 0.3 0.15 10.4 0.3 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like FAD_binding_3 PF01494.19 EPS33110.1 - 0.12 11.5 0.3 0.26 10.5 0.3 1.5 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.12 EPS33110.1 - 0.5 9.4 1.7 0.81 8.7 0.6 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein RPE65 PF03055.15 EPS33111.1 - 7.7e-117 391.3 0.0 8.8e-117 391.1 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Mito_carr PF00153.27 EPS33112.1 - 9.6e-59 195.3 3.9 3.2e-19 68.7 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PT-VENN PF04829.13 EPS33112.1 - 1.8 8.7 4.6 2.2 8.4 0.2 2.7 3 0 0 3 3 3 0 Pre-toxin domain with VENN motif CFEM PF05730.11 EPS33113.1 - 2.8e-11 43.3 10.0 5.6e-11 42.4 10.0 1.5 1 0 0 1 1 1 1 CFEM domain GAD-like PF08887.11 EPS33114.1 - 0.028 14.2 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 GAD-like domain HET PF06985.11 EPS33115.1 - 7e-08 32.9 4.5 1.1e-06 29.0 0.4 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) NDUF_C2 PF06374.11 EPS33116.1 - 0.1 12.8 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) PAN_1 PF00024.26 EPS33119.1 - 1.1e-05 25.3 0.3 1.2e-05 25.1 0.3 1.1 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 EPS33119.1 - 0.0011 18.9 1.0 0.0015 18.4 1.0 1.2 1 0 0 1 1 1 1 PAN domain COesterase PF00135.28 EPS33120.1 - 2.3e-78 264.3 0.0 3e-78 264.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EPS33120.1 - 3.1e-09 37.0 0.2 1.8e-08 34.5 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EPS33120.1 - 0.00046 19.2 0.0 0.45 9.3 0.0 2.2 2 0 0 2 2 2 2 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 EPS33120.1 - 0.029 13.8 0.8 0.055 12.9 0.8 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Med4 PF10018.9 EPS33121.1 - 9.8e-44 149.4 0.4 9.8e-44 149.4 0.4 1.4 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 TonB_N PF16031.5 EPS33121.1 - 0.027 15.0 24.3 0.061 13.8 24.3 1.5 1 0 0 1 1 1 0 TonB polyproline region FeoB_Cyto PF17910.1 EPS33121.1 - 0.21 12.2 0.2 0.21 12.2 0.2 1.8 2 0 0 2 2 2 0 FeoB cytosolic helical domain PspB PF06667.12 EPS33121.1 - 0.27 11.3 0.6 1.3 9.1 0.1 2.1 2 0 0 2 2 2 0 Phage shock protein B DUF4407 PF14362.6 EPS33121.1 - 1 8.7 4.3 2 7.7 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Zn_clus PF00172.18 EPS33122.1 - 2.3e-08 34.0 11.6 4.3e-08 33.1 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EPS33122.1 - 0.0034 16.3 0.2 0.0062 15.4 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Glyco_hydro_92 PF07971.12 EPS33123.1 - 1.7e-149 498.7 0.4 2.1e-149 498.4 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92N PF17678.1 EPS33123.1 - 2.1e-53 181.7 0.6 8e-53 179.8 0.6 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 92 N-terminal domain RabGAP-TBC PF00566.18 EPS33124.1 - 1.4e-49 168.7 0.6 7e-49 166.4 0.0 2.5 3 0 0 3 3 3 1 Rab-GTPase-TBC domain DUF1512 PF07431.12 EPS33124.1 - 0.31 10.0 0.3 0.54 9.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) DNA_topoisoIV PF00521.20 EPS33125.1 - 7.5e-137 456.7 0.2 1.4e-136 455.8 0.2 1.5 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 EPS33125.1 - 9.3e-53 177.9 3.1 2.8e-52 176.3 3.1 1.9 1 0 0 1 1 1 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 EPS33125.1 - 4.6e-26 91.3 0.7 1.1e-25 90.1 0.7 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 EPS33125.1 - 1.2e-15 57.9 0.1 3.2e-15 56.6 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 EPS33125.1 - 4.1e-07 30.2 0.1 2e-06 27.9 0.0 2.3 2 0 0 2 2 2 1 Toprim domain Cytochrome_CBB3 PF13442.6 EPS33127.1 - 0.043 14.1 0.1 0.068 13.5 0.1 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III Reticulon PF02453.17 EPS33128.1 - 3.5e-26 92.1 2.6 4.8e-26 91.6 2.6 1.2 1 0 0 1 1 1 1 Reticulon Cytochrome-c551 PF10643.9 EPS33128.1 - 0.016 14.8 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 MRP-S28 PF10213.9 EPS33128.1 - 0.07 13.5 0.0 0.15 12.5 0.0 1.5 2 0 0 2 2 2 0 Mitochondrial ribosomal subunit protein INCENP_ARK-bind PF03941.15 EPS33129.1 - 5.7e-16 58.2 1.6 2.8e-15 56.0 1.6 2.4 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region PDZ_1 PF12812.7 EPS33130.1 - 2e-53 178.3 0.0 2.2e-34 117.3 0.0 2.6 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.6 EPS33130.1 - 7.3e-25 88.6 1.0 4.8e-22 79.5 0.1 2.5 2 0 0 2 2 2 2 Trypsin-like peptidase domain PDZ_6 PF17820.1 EPS33130.1 - 1.8e-18 66.1 0.2 1.3e-09 37.7 0.2 4.6 4 0 0 4 4 4 3 PDZ domain PDZ_2 PF13180.6 EPS33130.1 - 9.6e-11 41.9 0.2 6.4e-05 23.2 0.0 4.4 5 0 0 5 5 5 3 PDZ domain PDZ PF00595.24 EPS33130.1 - 1.1e-08 35.3 0.0 0.0011 19.2 0.0 3.7 3 0 0 3 3 3 2 PDZ domain Trypsin PF00089.26 EPS33130.1 - 0.00016 21.5 0.0 0.00065 19.6 0.0 2.0 1 1 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.6 EPS33130.1 - 0.0021 18.0 0.5 0.34 10.9 0.1 3.8 5 0 0 5 5 5 1 Tricorn protease PDZ domain 4HPAD_g_N PF18671.1 EPS33130.1 - 0.03 14.0 0.0 0.11 12.2 0.0 2.0 1 0 0 1 1 1 0 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal Peptidase_S46 PF10459.9 EPS33130.1 - 0.057 12.1 0.1 0.11 11.1 0.1 1.3 1 0 0 1 1 1 0 Peptidase S46 DUF31 PF01732.16 EPS33130.1 - 0.12 11.9 0.2 0.18 11.3 0.2 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) Peptidase_S7 PF00949.21 EPS33130.1 - 0.13 12.1 0.1 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease SSXT PF05030.12 EPS33131.1 - 3.1e-07 29.9 0.0 0.011 15.4 0.0 2.5 2 0 0 2 2 2 2 SSXT protein (N-terminal region) TFIIA PF03153.13 EPS33131.1 - 2.3 8.1 16.6 2.7 7.9 16.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Glyco_hydro_10 PF00331.20 EPS33132.1 - 7.9e-105 350.5 1.3 9.2e-105 350.3 1.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.18 EPS33132.1 - 7.1e-14 51.5 15.1 2.6e-13 49.6 15.1 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain Ribonuclease PF00545.20 EPS33132.1 - 0.14 12.9 0.0 0.36 11.6 0.0 1.7 1 0 0 1 1 1 0 ribonuclease Toxin_7 PF05980.12 EPS33132.1 - 0.18 12.1 4.4 0.41 10.9 4.4 1.6 1 0 0 1 1 1 0 Toxin 7 TPR_1 PF00515.28 EPS33133.1 - 3.1e-09 36.3 1.6 0.0017 18.1 0.0 4.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EPS33133.1 - 2.6e-08 33.3 0.9 0.0067 16.5 0.0 4.1 4 1 1 5 5 5 2 Tetratricopeptide repeat DUF3808 PF10300.9 EPS33133.1 - 0.0024 16.7 0.3 0.0038 16.0 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) ANAPC3 PF12895.7 EPS33133.1 - 0.0034 17.6 0.5 0.0069 16.6 0.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EPS33133.1 - 0.0036 17.8 0.3 0.014 15.9 0.3 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 EPS33133.1 - 0.0037 17.5 0.4 0.06 13.7 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EPS33133.1 - 0.015 15.9 0.1 0.091 13.4 0.0 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EPS33133.1 - 0.036 14.9 0.2 0.19 12.6 0.2 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Pox_T4_N PF04491.12 EPS33133.1 - 0.092 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Poxvirus T4 protein, N terminus Iso_dh PF00180.20 EPS33134.1 - 2.2e-100 336.2 0.0 3.3e-100 335.6 0.0 1.3 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase CLZ PF16526.5 EPS33135.1 - 0.0018 18.6 0.9 0.0037 17.6 0.9 1.5 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CCDC32 PF14989.6 EPS33135.1 - 0.13 12.3 1.2 0.69 9.9 0.0 2.4 3 0 0 3 3 3 0 Coiled-coil domain containing 32 peroxidase PF00141.23 EPS33136.1 - 4.5e-44 150.9 0.0 6.7e-44 150.3 0.0 1.3 1 0 0 1 1 1 1 Peroxidase DUF4003 PF13170.6 EPS33136.1 - 0.076 12.4 0.0 0.22 10.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4003) RHIM PF12721.7 EPS33137.1 - 0.068 13.7 0.1 5.1 7.7 0.1 3.0 2 0 0 2 2 2 0 RIP homotypic interaction motif Ribosomal_S13 PF00416.22 EPS33138.1 - 4.1e-56 188.8 3.0 4.8e-56 188.6 3.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 EPS33138.1 - 0.0099 14.7 0.0 0.01 14.7 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF1822 PF08852.11 EPS33138.1 - 0.011 14.8 0.0 0.015 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1822) HHH_6 PF14579.6 EPS33138.1 - 0.048 13.9 0.1 0.14 12.4 0.1 1.8 1 1 0 1 1 1 0 Helix-hairpin-helix motif DUF2746 PF10874.8 EPS33138.1 - 0.13 12.7 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) CH PF00307.31 EPS33138.1 - 0.14 12.4 0.0 0.23 11.6 0.0 1.4 1 1 0 1 1 1 0 Calponin homology (CH) domain Peptidase_S10 PF00450.22 EPS33139.1 - 1.3e-129 433.3 0.9 1.6e-129 433.0 0.9 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 EPS33139.1 - 2.2e-15 57.3 0.0 5.3e-15 56.1 0.0 1.7 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Phasin PF05597.11 EPS33139.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) SBDS_C PF09377.10 EPS33140.1 - 1.6e-43 147.4 0.0 2.3e-43 146.9 0.0 1.2 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 EPS33140.1 - 1.4e-30 105.2 0.0 2.6e-30 104.3 0.0 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SUIM_assoc PF16619.5 EPS33140.1 - 0.0078 16.2 2.3 0.015 15.3 2.3 1.4 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Ribosomal_60s PF00428.19 EPS33140.1 - 0.012 16.2 3.1 0.37 11.4 0.4 2.8 2 1 0 2 2 2 0 60s Acidic ribosomal protein PALP PF00291.25 EPS33141.1 - 1.3e-40 139.7 1.5 1.8e-40 139.2 1.5 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PRR18 PF15671.5 EPS33141.1 - 0.0029 17.5 7.2 0.0059 16.5 7.2 1.5 1 0 0 1 1 1 1 Proline-rich protein family 18 zf-U1 PF06220.12 EPS33144.1 - 0.19 11.5 0.0 0.32 10.8 0.0 1.2 1 0 0 1 1 1 0 U1 zinc finger AMP-binding PF00501.28 EPS33148.1 - 3.1e-39 134.8 0.0 4.6e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EPS33148.1 - 8.7e-05 22.4 0.4 8.7e-05 22.4 0.4 2.0 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus Pyridoxal_deC PF00282.19 EPS33149.1 - 6.3e-81 272.0 0.0 9.8e-81 271.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Lactamase_B_2 PF12706.7 EPS33150.1 - 1.7e-12 47.3 0.3 5e-12 45.8 0.2 1.8 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EPS33150.1 - 1.9e-10 40.8 0.2 5.5e-10 39.4 0.0 1.9 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EPS33150.1 - 0.0016 18.5 0.8 0.0074 16.3 0.8 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Glyco_transf_4 PF13439.6 EPS33150.1 - 0.13 12.3 1.1 0.75 9.8 1.2 1.8 1 1 1 2 2 2 0 Glycosyltransferase Family 4 Sulfatase PF00884.23 EPS33153.1 - 2.8e-59 201.0 0.1 4.6e-59 200.3 0.1 1.4 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.8 EPS33153.1 - 4.7e-22 77.5 0.4 9.7e-22 76.5 0.4 1.6 1 0 0 1 1 1 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.22 EPS33153.1 - 3.5e-10 40.0 0.1 7.4e-09 35.7 0.1 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.6 EPS33153.1 - 0.0049 17.6 0.3 0.019 15.7 0.2 1.9 1 1 1 2 2 2 1 C-terminal region of aryl-sulfatase DUF229 PF02995.17 EPS33153.1 - 0.024 13.2 0.0 0.031 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF1501 PF07394.12 EPS33153.1 - 0.093 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) EMP70 PF02990.16 EPS33154.1 - 2.7e-191 636.8 1.7 3.4e-191 636.4 1.7 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 DDDD PF10161.9 EPS33154.1 - 0.27 11.0 0.7 33 4.3 0.0 2.9 2 0 0 2 2 2 0 Putative mitochondrial precursor protein ubiquitin PF00240.23 EPS33155.1 - 9.8e-20 70.1 0.0 1.5e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 EPS33155.1 - 1.3e-07 31.4 0.1 3.5e-07 30.0 0.1 1.8 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.8 EPS33155.1 - 3.2e-07 30.1 0.0 5.4e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 EPS33155.1 - 0.00025 21.1 0.0 0.00045 20.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EPS33155.1 - 0.00032 21.2 0.0 0.00096 19.7 0.0 1.7 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain YukD PF08817.10 EPS33155.1 - 0.0011 19.6 0.0 0.0034 18.0 0.0 1.9 1 1 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD HOIP-UBA PF16678.5 EPS33155.1 - 0.058 13.4 0.0 0.096 12.7 0.0 1.3 1 0 0 1 1 1 0 HOIP UBA domain pair Ubiquitin_2 PF14560.6 EPS33155.1 - 0.061 13.8 0.1 0.21 12.0 0.1 1.8 1 1 0 1 1 1 0 Ubiquitin-like domain GerD PF17898.1 EPS33155.1 - 0.89 9.5 4.2 2.3 8.2 4.1 1.7 1 1 0 1 1 1 0 Spore germination GerD central core domain MMS1_N PF10433.9 EPS33156.1 - 4.2e-158 527.0 0.0 6e-158 526.5 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EPS33156.1 - 1.1e-99 333.9 0.0 1.8e-98 329.8 0.0 2.6 3 0 0 3 3 3 1 CPSF A subunit region ANAPC4_WD40 PF12894.7 EPS33156.1 - 0.043 14.1 0.0 0.41 11.0 0.0 2.7 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Bul1_N PF04425.12 EPS33157.1 - 2e-05 23.6 0.5 0.00053 18.9 0.1 2.5 2 1 1 3 3 3 1 Bul1 N terminus Arrestin_N PF00339.29 EPS33157.1 - 0.00019 21.5 0.0 0.00058 19.9 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.12 EPS33157.1 - 0.00031 20.2 0.0 0.0005 19.6 0.0 1.2 1 0 0 1 1 1 1 Bul1 C terminus Glyco_hydro_18 PF00704.28 EPS33160.1 - 3.4e-83 279.9 8.5 4e-83 279.7 8.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 BP28CT PF08146.12 EPS33161.1 - 2.3e-42 144.5 1.0 4e-41 140.5 0.2 3.0 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 EPS33161.1 - 1.2e-23 83.7 5.7 1.2e-23 83.7 5.7 4.3 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.6 EPS33161.1 - 2.1e-08 34.4 3.4 0.63 10.5 0.0 7.2 6 1 1 7 7 7 3 HEAT repeats HEAT PF02985.22 EPS33161.1 - 0.0017 18.5 3.0 2.6 8.6 0.0 5.8 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 EPS33161.1 - 0.16 12.6 15.4 9.3 6.9 0.2 7.2 5 2 2 7 7 7 0 HEAT-like repeat PMC2NT PF08066.12 EPS33161.1 - 0.18 12.5 3.4 0.7 10.6 0.3 3.8 3 0 0 3 3 3 0 PMC2NT (NUC016) domain NRDE-2 PF08424.10 EPS33162.1 - 7.9e-77 258.5 0.2 6.6e-76 255.5 0.1 2.3 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 EPS33162.1 - 2.8 9.0 11.0 13 6.9 0.0 5.1 5 1 1 6 6 6 0 Tetratricopeptide repeat NAD_binding_6 PF08030.12 EPS33163.1 - 1.4e-22 80.5 0.0 2.2e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EPS33163.1 - 1.4e-21 76.6 0.0 3.1e-21 75.5 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 EPS33163.1 - 1.7e-20 73.4 12.2 4.3e-20 72.1 12.2 1.7 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.24 EPS33163.1 - 0.059 13.7 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EPS33163.1 - 0.084 13.5 0.0 3.8 8.2 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Peptidase_C12 PF01088.21 EPS33165.1 - 1.7e-44 152.1 0.0 2e-44 151.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Pkinase PF00069.25 EPS33166.1 - 2.2e-16 60.0 0.0 2.9e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.14 EPS33166.1 - 1.2e-07 31.3 0.0 2.6e-07 30.2 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EPS33166.1 - 4.8e-07 29.4 0.0 6.4e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EPS33166.1 - 2.8e-06 27.4 0.0 7.3e-06 26.1 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EPS33166.1 - 3e-06 26.7 0.0 4.4e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EPS33166.1 - 0.00076 18.4 0.0 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 EPS33166.1 - 0.0044 16.6 0.0 0.0076 15.9 0.0 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 EPS33166.1 - 0.0059 16.2 0.0 0.0091 15.6 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.11 EPS33166.1 - 0.0092 15.1 0.1 0.014 14.5 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 PIP49_C PF12260.8 EPS33166.1 - 0.048 13.3 0.0 0.072 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 APH PF01636.23 EPS33167.1 - 1.1e-09 38.6 0.1 1.3e-08 35.1 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family UDG PF03167.19 EPS33168.1 - 1.1e-17 64.4 0.0 1.7e-17 63.8 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Macoilin PF09726.9 EPS33168.1 - 0.12 11.0 1.0 0.12 10.9 1.0 1.0 1 0 0 1 1 1 0 Macoilin family RSRP PF17069.5 EPS33168.1 - 0.7 9.4 17.6 1.1 8.7 17.6 1.3 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 SBDS PF01172.18 EPS33169.1 - 6.6e-24 83.8 0.1 8.7e-24 83.4 0.1 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein RhoGEF PF00621.20 EPS33170.1 - 5.2e-18 65.9 0.2 1.1e-17 64.8 0.2 1.6 1 0 0 1 1 1 1 RhoGEF domain Nas2_N PF18265.1 EPS33171.1 - 6.3e-30 102.9 0.2 9.8e-30 102.3 0.2 1.3 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 EPS33171.1 - 3.3e-13 49.3 0.1 5.5e-13 48.5 0.1 1.4 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EPS33171.1 - 1.2e-08 35.2 0.0 2.6e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 EPS33171.1 - 7e-08 32.9 0.0 1.6e-07 31.7 0.0 1.5 2 0 0 2 2 2 1 GRASP55/65 PDZ-like domain PDZ PF00595.24 EPS33171.1 - 3.7e-06 27.2 0.0 6.6e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Ras PF00071.22 EPS33172.1 - 5.5e-49 165.9 0.0 6.8e-49 165.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EPS33172.1 - 1.6e-29 102.6 0.0 4.1e-29 101.2 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPS33172.1 - 8.8e-11 41.6 0.0 1.3e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 EPS33172.1 - 0.00013 22.3 0.1 0.00087 19.7 0.1 2.1 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.23 EPS33172.1 - 0.00024 21.2 0.0 0.00048 20.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EPS33172.1 - 0.0052 16.2 0.0 0.007 15.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 EPS33172.1 - 0.018 14.2 1.5 1.7 7.7 0.1 2.6 2 1 1 3 3 3 0 G-protein alpha subunit Pox_A32 PF04665.12 EPS33172.1 - 0.021 14.3 0.1 0.039 13.4 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_7 PF12775.7 EPS33172.1 - 0.025 14.1 0.1 0.042 13.4 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 EPS33172.1 - 0.028 14.3 0.1 8.7 6.2 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 EPS33172.1 - 0.057 13.1 0.1 0.095 12.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EPS33172.1 - 0.094 12.9 0.2 0.22 11.7 0.2 1.6 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EPS33172.1 - 0.1 12.6 0.1 0.21 11.6 0.1 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 EPS33172.1 - 0.11 12.9 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 EPS33172.1 - 0.17 11.2 0.3 0.31 10.3 0.0 1.5 2 0 0 2 2 2 0 Septin SNF2_N PF00176.23 EPS33173.1 - 8.5e-63 212.2 0.2 1.4e-62 211.4 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EPS33173.1 - 1.7e-17 63.7 0.0 4.1e-17 62.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 EPS33173.1 - 1.7e-08 34.1 2.6 4.2e-08 32.9 2.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EPS33173.1 - 1.2e-07 31.5 3.8 2.4e-07 30.5 3.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPS33173.1 - 2.1e-06 27.6 2.6 4.6e-06 26.6 2.6 1.6 1 0 0 1 1 1 1 RING-type zinc-finger ResIII PF04851.15 EPS33173.1 - 4.3e-06 26.8 0.0 1.1e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.6 EPS33173.1 - 3e-05 24.2 5.4 7.3e-05 23.0 5.4 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EPS33173.1 - 5.6e-05 22.9 6.7 0.00011 22.0 6.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EPS33173.1 - 0.00021 21.3 6.5 0.00044 20.4 6.5 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EPS33173.1 - 0.00024 21.0 4.9 0.00057 19.8 4.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain DEAD PF00270.29 EPS33173.1 - 0.0042 16.9 0.2 0.018 14.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Prok-RING_4 PF14447.6 EPS33173.1 - 0.0044 16.8 5.2 0.064 13.1 6.0 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EPS33173.1 - 0.011 15.6 5.1 0.026 14.3 5.1 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain GAGA PF09237.11 EPS33173.1 - 0.094 12.5 0.2 0.38 10.6 0.0 2.1 2 0 0 2 2 2 0 GAGA factor Zn_Tnp_IS91 PF14319.6 EPS33173.1 - 0.1 12.6 1.4 2.6 8.1 0.5 2.6 2 0 0 2 2 2 0 Transposase zinc-binding domain DUF5072 PF16807.5 EPS33173.1 - 0.16 12.0 0.5 0.67 10.0 0.0 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5072) DZR PF12773.7 EPS33173.1 - 0.4 10.7 4.0 0.94 9.6 4.0 1.6 1 0 0 1 1 1 0 Double zinc ribbon SCP2 PF02036.17 EPS33174.1 - 4.9e-27 94.4 0.7 5.9e-27 94.1 0.7 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 EPS33174.1 - 1.2e-06 28.9 0.1 1.4e-06 28.6 0.1 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal ABC_tran PF00005.27 EPS33175.1 - 1.8e-44 151.6 0.0 3.5e-27 95.6 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EPS33175.1 - 1.7e-37 129.6 19.7 1.1e-23 84.2 9.4 3.7 4 0 0 4 4 4 3 ABC transporter transmembrane region SMC_N PF02463.19 EPS33175.1 - 6.1e-13 48.7 6.4 1.3e-06 28.0 0.2 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EPS33175.1 - 1.8e-05 25.3 1.9 0.0034 17.9 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EPS33175.1 - 2.3e-05 24.3 4.1 2 8.1 0.2 4.3 3 1 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EPS33175.1 - 5e-05 23.0 5.5 0.012 15.3 0.2 2.9 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EPS33175.1 - 0.0001 22.6 0.9 0.59 10.4 0.0 3.0 2 1 0 2 2 2 2 AAA domain T2SSE PF00437.20 EPS33175.1 - 0.00018 20.7 0.2 0.32 10.0 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein RsgA_GTPase PF03193.16 EPS33175.1 - 0.00027 20.9 0.1 0.79 9.6 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_25 PF13481.6 EPS33175.1 - 0.0006 19.4 0.7 0.019 14.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EPS33175.1 - 0.00077 19.9 0.3 0.54 10.6 0.1 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_15 PF13175.6 EPS33175.1 - 0.0022 17.8 0.2 0.3 10.7 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 EPS33175.1 - 0.016 15.3 0.1 2.4 8.2 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF87 PF01935.17 EPS33175.1 - 0.019 15.0 0.6 0.019 15.0 0.6 1.8 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_33 PF13671.6 EPS33175.1 - 0.028 14.6 0.0 7.4 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EPS33175.1 - 0.036 14.0 4.7 4 7.3 0.4 3.2 2 1 1 3 3 3 0 NACHT domain TsaE PF02367.17 EPS33175.1 - 0.039 14.0 0.5 0.31 11.0 0.3 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE cobW PF02492.19 EPS33175.1 - 0.046 13.3 2.4 0.69 9.5 0.4 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TrwB_AAD_bind PF10412.9 EPS33175.1 - 0.051 12.5 2.3 0.57 9.0 0.2 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_30 PF13604.6 EPS33175.1 - 0.054 13.2 1.2 10 5.8 0.0 2.7 2 1 0 2 2 2 0 AAA domain DEAD PF00270.29 EPS33175.1 - 0.11 12.3 0.4 31 4.3 0.0 3.2 3 0 0 3 3 3 0 DEAD/DEAH box helicase FtsK_SpoIIIE PF01580.18 EPS33175.1 - 0.13 11.6 1.5 4.1 6.7 0.1 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 EPS33175.1 - 0.22 10.8 0.2 6.5 6.0 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Oleosin PF01277.17 EPS33175.1 - 0.31 10.8 4.9 0.28 10.9 1.9 2.5 2 0 0 2 2 2 0 Oleosin Dynamin_N PF00350.23 EPS33175.1 - 0.35 10.9 0.9 26 4.8 0.1 2.4 2 0 0 2 2 2 0 Dynamin family IstB_IS21 PF01695.17 EPS33175.1 - 0.35 10.6 3.0 20 4.9 0.0 3.8 4 0 0 4 4 4 0 IstB-like ATP binding protein Pox_A32 PF04665.12 EPS33175.1 - 0.61 9.5 1.7 15 4.9 0.2 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein Cyclase PF04199.13 EPS33176.1 - 1.4e-14 54.5 0.0 1.9e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Pectate_lyase_3 PF12708.7 EPS33177.1 - 1.8e-102 341.7 19.1 2e-86 289.3 7.4 2.9 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 EPS33177.1 - 3.5e-07 29.8 1.5 0.015 15.0 0.1 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Ran_BP1 PF00638.18 EPS33179.1 - 1.6e-09 38.0 0.0 4e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 RanBP1 domain Mitoc_mL59 PF18126.1 EPS33179.1 - 2.2 8.6 8.7 12 6.2 8.7 2.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein mL59 Ribosomal_L31e PF01198.19 EPS33180.1 - 2.4e-39 133.4 0.4 3.2e-39 133.0 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e CN_hydrolase PF00795.22 EPS33181.1 - 1.1e-61 208.4 0.0 1.3e-61 208.3 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase ATG2_CAD PF13329.6 EPS33185.1 - 1.6e-46 157.9 0.2 5.2e-46 156.2 0.2 1.9 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.11 EPS33185.1 - 1.1e-28 99.4 0.1 3.9e-28 97.6 0.0 2.0 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 EPS33185.1 - 0.18 11.6 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 Vacuolar-sorting-associated 13 protein C-terminal A_deaminase PF00962.22 EPS33186.1 - 4.1e-24 85.5 0.0 5.9e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase RNase_T PF00929.24 EPS33186.1 - 0.11 13.1 0.0 0.47 11.0 0.0 1.9 2 0 0 2 2 2 0 Exonuclease Nucleos_tra2_C PF07662.13 EPS33188.1 - 1.8e-72 243.5 0.3 1.8e-72 243.5 0.3 2.6 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.20 EPS33188.1 - 2.5e-24 85.7 4.9 2.5e-24 85.7 4.9 2.3 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus UQ_con PF00179.26 EPS33189.1 - 7.2e-49 165.0 0.0 8.5e-49 164.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EPS33189.1 - 0.00016 21.4 0.1 0.00028 20.6 0.0 1.4 2 0 0 2 2 2 1 Prokaryotic E2 family B RWD PF05773.22 EPS33189.1 - 0.00017 21.9 0.1 0.00036 20.8 0.1 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.13 EPS33189.1 - 0.0025 17.7 0.0 0.0039 17.1 0.0 1.4 1 0 0 1 1 1 1 UEV domain Pkinase PF00069.25 EPS33190.1 - 1.6e-59 201.5 0.0 2e-59 201.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS33190.1 - 7.2e-25 87.7 0.0 9.9e-25 87.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EPS33190.1 - 3.7e-08 33.0 0.0 5.2e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EPS33190.1 - 0.0015 18.5 0.0 0.56 10.1 0.0 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EPS33190.1 - 0.0081 15.5 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family F-box-like PF12937.7 EPS33191.1 - 2e-05 24.4 0.2 4.2e-05 23.3 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EPS33191.1 - 0.0013 18.5 1.0 0.003 17.4 1.0 1.7 1 0 0 1 1 1 1 F-box domain MFS_1 PF07690.16 EPS33192.1 - 1.6e-44 152.3 24.6 8e-38 130.3 19.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EPS33192.1 - 6.7e-10 38.1 12.4 4.2e-05 22.3 7.6 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 EPS33192.1 - 7.4e-07 28.4 11.6 0.012 14.4 7.7 3.9 3 1 1 4 4 4 4 MFS_1 like family OATP PF03137.20 EPS33192.1 - 0.00022 19.7 9.2 0.0016 16.9 1.3 2.8 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family LacY_symp PF01306.19 EPS33192.1 - 0.00026 19.9 5.3 0.0068 15.2 0.1 3.0 3 0 0 3 3 3 2 LacY proton/sugar symporter MFS_4 PF06779.14 EPS33192.1 - 0.0007 19.0 5.2 0.0007 19.0 5.2 2.6 2 1 1 3 3 3 1 Uncharacterised MFS-type transporter YbfB AMP-binding PF00501.28 EPS33193.1 - 2.7e-63 214.0 0.0 3.8e-63 213.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.20 EPS33193.1 - 8.1e-18 65.4 0.0 1.6e-17 64.4 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.25 EPS33193.1 - 2.1e-07 31.2 0.0 5e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.7 EPS33193.1 - 0.00037 21.2 0.1 0.0016 19.1 0.1 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family AMP-binding_C PF13193.6 EPS33193.1 - 0.0035 18.3 2.0 0.0056 17.6 0.6 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Hydrolase_4 PF12146.8 EPS33193.1 - 0.1 11.9 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 2OG-FeII_Oxy PF03171.20 EPS33194.1 - 3e-06 27.7 0.0 5.3e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EPS33194.1 - 5.6e-06 27.1 0.0 8.8e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Haem_oxygenas_2 PF14518.6 EPS33195.1 - 2.1e-33 115.6 0.2 3.3e-33 114.9 0.2 1.3 1 0 0 1 1 1 1 Iron-containing redox enzyme FAD_binding_3 PF01494.19 EPS33196.1 - 5.7e-06 25.8 0.1 8.5e-06 25.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Mannosidase_ig PF17786.1 EPS33197.1 - 0.14 12.8 0.1 0.79 10.4 0.0 2.0 1 1 1 2 2 2 0 Mannosidase Ig/CBM-like domain DHBP_synthase PF00926.19 EPS33198.1 - 1.2e-80 269.6 0.1 1.5e-80 269.3 0.1 1.1 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase TFA2_Winged_2 PF18121.1 EPS33199.1 - 1.3e-21 76.0 0.8 3.6e-21 74.6 0.8 1.8 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 EPS33199.1 - 2.5e-20 72.5 0.0 1.3e-19 70.2 0.0 2.2 2 0 0 2 2 2 1 TFIIE beta subunit core domain STI1 PF17830.1 EPS33199.1 - 0.018 14.9 0.3 0.82 9.7 0.0 3.0 3 0 0 3 3 3 0 STI1 domain TPR_MLP1_2 PF07926.12 EPS33200.1 - 1.1e-35 122.5 28.3 1.1e-35 122.5 28.3 17.4 10 5 7 17 17 17 7 TPR/MLP1/MLP2-like protein KASH_CCD PF14662.6 EPS33200.1 - 0.002 18.0 24.3 0.002 18.0 24.3 15.3 7 3 7 14 14 14 2 Coiled-coil region of CCDC155 or KASH Rootletin PF15035.6 EPS33200.1 - 0.0065 16.5 3.4 0.0065 16.5 3.4 13.8 6 5 7 13 13 13 3 Ciliary rootlet component, centrosome cohesion Hexapep PF00132.24 EPS33201.1 - 9.8e-08 31.4 10.1 0.0093 15.7 2.5 4.1 2 2 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EPS33201.1 - 0.00052 19.7 2.5 0.00057 19.6 0.3 2.2 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 EPS33201.1 - 0.2 10.5 0.0 7.7 5.3 0.0 2.0 2 0 0 2 2 2 0 L-fucokinase Acid_PPase PF12689.7 EPS33203.1 - 1.7e-70 236.3 0.0 2e-70 236.0 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase Sec63 PF02889.16 EPS33204.1 - 2.9e-27 95.4 0.0 4.7e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 EPS33204.1 - 4.1e-25 88.6 0.1 7.9e-25 87.6 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EPS33204.1 - 2.4e-13 50.5 0.0 4.6e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EPS33204.1 - 5.7e-08 33.1 0.0 3.1e-07 30.7 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 EPS33204.1 - 0.00043 20.1 0.0 0.00081 19.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EPS33204.1 - 0.0023 18.2 0.0 0.0059 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EPS33204.1 - 0.0023 18.3 0.0 0.0055 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Hyr1 PF15789.5 EPS33204.1 - 0.032 13.8 0.0 0.084 12.4 0.0 1.7 1 0 0 1 1 1 0 Hyphally regulated cell wall GPI-anchored protein 1 CHDCT2 PF08074.11 EPS33204.1 - 0.087 13.0 0.1 0.18 12.0 0.1 1.5 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain UvrD-helicase PF00580.21 EPS33204.1 - 0.088 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain HHH_5 PF14520.6 EPS33204.1 - 0.15 12.7 0.1 0.35 11.5 0.1 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain PAC3 PF10178.9 EPS33204.1 - 0.16 12.1 0.0 0.57 10.4 0.0 1.9 1 0 0 1 1 1 0 Proteasome assembly chaperone 3 Nuc_sug_transp PF04142.15 EPS33205.1 - 9.3e-73 245.1 4.1 1.3e-72 244.6 4.1 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 EPS33205.1 - 0.0093 15.2 10.5 0.028 13.6 9.3 2.0 1 1 1 2 2 2 1 UAA transporter family EamA PF00892.20 EPS33205.1 - 0.57 10.4 31.0 0.049 13.8 12.9 3.3 2 2 0 2 2 2 0 EamA-like transporter family HORMA PF02301.18 EPS33208.1 - 1.1e-13 51.3 0.0 1.7e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 HORMA domain Macoilin PF09726.9 EPS33208.1 - 0.031 12.9 2.0 0.04 12.5 2.0 1.1 1 0 0 1 1 1 0 Macoilin family CPL PF08144.11 EPS33208.1 - 0.07 13.5 0.3 0.13 12.6 0.3 1.4 1 0 0 1 1 1 0 CPL (NUC119) domain WD40 PF00400.32 EPS33209.1 - 1.6e-39 133.1 22.1 3e-05 24.7 0.4 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 EPS33209.1 - 6.8e-08 32.3 0.0 1.3e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EPS33209.1 - 4.3e-07 29.6 0.1 1.1e-06 28.3 0.1 1.7 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 EPS33209.1 - 6.5e-07 29.6 1.2 0.55 10.6 0.0 4.4 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain F-box_4 PF15966.5 EPS33209.1 - 0.0063 16.4 0.2 0.016 15.1 0.2 1.7 1 0 0 1 1 1 1 F-box Nup160 PF11715.8 EPS33209.1 - 0.021 13.5 10.2 3.4 6.2 0.2 5.1 2 1 2 5 5 5 0 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 EPS33209.1 - 3.4 6.5 5.4 6.4 5.6 0.1 3.6 4 2 0 4 4 4 0 Partner and localizer of BRCA2 WD40 domain MMR_HSR1 PF01926.23 EPS33210.1 - 6.2e-19 68.2 0.0 8.9e-19 67.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EPS33210.1 - 4.4e-06 26.9 0.0 0.00022 21.3 0.0 2.2 1 1 1 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 EPS33210.1 - 7.5e-05 22.7 0.1 0.0041 17.0 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 EPS33210.1 - 0.00024 20.7 0.0 0.00032 20.2 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 EPS33210.1 - 0.001 18.7 0.0 0.0079 15.7 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain IIGP PF05049.13 EPS33210.1 - 0.012 14.7 0.0 0.028 13.5 0.0 1.5 1 1 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AIG1 PF04548.16 EPS33210.1 - 0.012 15.0 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 AIG1 family SRPRB PF09439.10 EPS33210.1 - 0.015 14.7 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 EPS33210.1 - 0.021 15.3 0.1 0.034 14.6 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 EPS33210.1 - 0.073 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 EPS33210.1 - 0.1 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Clat_adaptor_s PF01217.20 EPS33211.1 - 6.9e-43 146.0 0.0 1.6e-42 144.8 0.0 1.5 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Ribosomal_L7Ae PF01248.26 EPS33212.1 - 3.8e-23 81.0 0.6 6.1e-23 80.4 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CLPTM1 PF05602.12 EPS33212.1 - 0.066 12.2 0.5 0.086 11.8 0.5 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) TAN PF11640.8 EPS33213.1 - 0.00034 20.8 0.1 0.0026 17.9 0.1 2.4 1 1 0 1 1 1 1 Telomere-length maintenance and DNA damage repair Cnd1 PF12717.7 EPS33213.1 - 0.0017 18.4 0.8 0.0085 16.1 0.8 2.1 1 1 1 2 2 2 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EPS33213.1 - 0.0019 17.8 1.6 0.38 10.3 0.3 3.6 3 1 0 3 3 3 1 CLASP N terminal Suppressor_APC PF11414.8 EPS33213.1 - 0.023 14.7 5.1 0.11 12.6 5.1 2.1 1 1 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein MMS19_N PF14500.6 EPS33213.1 - 0.027 14.0 0.3 0.077 12.6 0.1 1.8 2 0 0 2 2 1 0 Dos2-interacting transcription regulator of RNA-Pol-II Proteasom_PSMB PF10508.9 EPS33213.1 - 0.031 12.8 0.2 0.088 11.3 0.1 1.7 1 1 0 1 1 1 0 Proteasome non-ATPase 26S subunit HEAT PF02985.22 EPS33213.1 - 0.057 13.7 2.0 3.4 8.2 0.5 3.8 3 0 0 3 3 3 0 HEAT repeat Golgin_A5 PF09787.9 EPS33213.1 - 0.11 11.9 11.9 0.3 10.5 11.9 1.6 1 0 0 1 1 1 0 Golgin subfamily A member 5 Tho2 PF11262.8 EPS33213.1 - 0.14 11.3 3.3 0.3 10.2 3.3 1.5 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 G-gamma PF00631.22 EPS33213.1 - 0.3 11.1 2.9 0.98 9.5 1.5 2.5 2 0 0 2 2 2 0 GGL domain Fez1 PF06818.15 EPS33213.1 - 0.53 10.7 9.3 0.097 13.1 5.1 1.9 2 0 0 2 2 2 0 Fez1 DUF724 PF05266.14 EPS33213.1 - 1.3 8.8 8.9 3.4 7.5 8.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ADIP PF11559.8 EPS33213.1 - 1.4 9.0 14.7 3.8 7.6 14.7 1.7 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding FapA PF03961.13 EPS33213.1 - 1.6 7.3 4.6 2.7 6.5 4.6 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF5320 PF17253.2 EPS33213.1 - 1.8 9.6 4.4 14 6.8 0.2 3.5 3 0 0 3 3 2 0 Family of unknown function (DUF5320) BST2 PF16716.5 EPS33213.1 - 2 9.0 8.2 21 5.8 1.2 3.2 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 Mod_r PF07200.13 EPS33213.1 - 2.1 8.4 11.5 3.1 7.9 9.6 2.2 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Atg14 PF10186.9 EPS33213.1 - 3.1 6.8 7.8 6.5 5.7 7.8 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SlyX PF04102.12 EPS33213.1 - 4.9 7.8 14.8 7.5 7.3 2.4 3.7 2 1 1 3 3 3 0 SlyX DUF4407 PF14362.6 EPS33213.1 - 5 6.4 14.0 1.3 8.3 9.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 EPS33213.1 - 6.1 5.6 14.9 35 3.1 14.9 2.1 1 1 0 1 1 1 0 Spc7 kinetochore protein WD40 PF00400.32 EPS33214.1 - 5.2e-52 172.7 9.1 2.6e-07 31.2 0.2 8.6 8 1 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS33214.1 - 1.5e-12 47.6 0.0 0.011 16.0 0.1 5.0 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EPS33214.1 - 4e-07 29.1 1.0 0.0056 15.4 0.1 3.9 4 1 1 5 5 5 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EPS33214.1 - 0.0075 15.1 0.0 3.5 6.3 0.0 3.5 4 0 0 4 4 4 2 Nup133 N terminal like LisH_TPL PF17814.1 EPS33214.1 - 0.18 11.5 0.0 0.6 9.8 0.0 2.0 1 1 0 1 1 1 0 LisH-like dimerisation domain Ribosomal_S17 PF00366.20 EPS33215.1 - 3.7e-14 52.6 3.2 3.7e-14 52.6 3.2 1.8 2 0 0 2 2 2 1 Ribosomal protein S17 FAD_binding_4 PF01565.23 EPS33218.1 - 9.5e-23 80.5 1.8 9.5e-23 80.5 1.8 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 EPS33218.1 - 9.2e-11 41.7 0.7 1.8e-10 40.8 0.7 1.5 1 0 0 1 1 1 1 Berberine and berberine like Glyco_transf_20 PF00982.21 EPS33219.1 - 1.9e-201 669.8 0.0 2.2e-201 669.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.11 EPS33219.1 - 0.021 14.6 0.1 0.045 13.5 0.1 1.6 1 0 0 1 1 1 0 Starch synthase catalytic domain BLACT_WH PF17778.1 EPS33220.1 - 7.6e-16 57.8 0.1 1.5e-15 56.9 0.1 1.5 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B PF00753.27 EPS33220.1 - 2e-15 57.3 2.9 5.2e-15 56.0 2.9 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EPS33220.1 - 7.8e-06 25.5 0.1 1.3e-05 24.9 0.1 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EPS33220.1 - 0.074 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Aconitase PF00330.20 EPS33221.1 - 1.4e-151 505.6 0.0 1.8e-151 505.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EPS33221.1 - 6.4e-43 146.2 0.0 1.2e-42 145.3 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain zf-C2H2_jaz PF12171.8 EPS33222.1 - 2.5e-09 37.2 6.3 3.9e-09 36.6 6.3 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EPS33222.1 - 0.002 18.4 0.2 0.0024 18.1 0.2 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 EPS33222.1 - 0.0022 18.4 4.1 0.0036 17.6 4.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EPS33222.1 - 0.01 15.8 3.1 0.019 15.0 3.1 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_4 PF13894.6 EPS33222.1 - 0.012 16.4 1.3 0.026 15.3 1.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-LYAR PF08790.11 EPS33222.1 - 0.037 13.9 0.2 0.077 12.9 0.2 1.5 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger zf-U1 PF06220.12 EPS33222.1 - 0.084 12.7 1.3 0.15 11.8 1.3 1.4 1 0 0 1 1 1 0 U1 zinc finger zf-C2H2 PF00096.26 EPS33222.1 - 0.13 12.7 1.5 0.25 11.9 1.5 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type Snurportin1 PF11538.8 EPS33222.1 - 2.9 8.1 8.9 2.3 8.5 0.4 3.3 4 0 0 4 4 4 0 Snurportin1 Mito_carr PF00153.27 EPS33223.1 - 8.7e-49 163.4 0.7 3.2e-20 71.9 0.1 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF2232 PF09991.9 EPS33223.1 - 0.018 14.2 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Glyco_hydro_18 PF00704.28 EPS33223.1 - 0.12 12.1 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 18 DUF3496 PF12001.8 EPS33223.1 - 0.15 12.4 0.2 0.25 11.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3496) Rad54_N PF08658.10 EPS33224.1 - 1.4e-58 198.1 0.5 3.1e-57 193.6 0.6 2.3 2 0 0 2 2 2 1 Rad54 N terminal SNF2_N PF00176.23 EPS33224.1 - 1.3e-56 191.9 0.0 1.8e-56 191.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EPS33224.1 - 2.8e-15 56.6 0.0 6.9e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPS33224.1 - 6.3e-07 29.6 0.0 1.3e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EPS33224.1 - 0.0013 18.0 0.0 0.0057 15.9 0.0 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 EPS33224.1 - 0.077 12.2 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase BRK PF07533.16 EPS33224.1 - 0.12 12.0 0.0 0.34 10.6 0.0 1.7 1 0 0 1 1 1 0 BRK domain Vac14_Fig4_bd PF11916.8 EPS33225.1 - 3.9e-81 271.0 8.6 3.9e-81 271.0 8.6 2.0 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 EPS33225.1 - 1.7e-43 147.1 0.1 3.3e-41 139.8 0.0 3.5 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EPS33225.1 - 4.1e-10 39.9 1.6 0.0039 17.7 0.0 5.0 4 1 1 5 5 5 2 HEAT-like repeat HEAT PF02985.22 EPS33225.1 - 5.8e-07 29.2 0.7 0.002 18.2 0.0 4.8 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 EPS33225.1 - 1.9e-05 24.8 0.6 0.072 13.1 0.4 2.7 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EPS33225.1 - 0.00049 20.4 1.3 1.7 9.1 0.0 4.5 4 1 0 4 4 4 1 HEAT repeats Arm PF00514.23 EPS33225.1 - 0.036 14.1 0.0 18 5.6 0.0 4.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF3385 PF11865.8 EPS33225.1 - 0.14 12.1 0.0 23 4.9 0.0 3.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3385) AIM24 PF01987.17 EPS33227.1 - 2.5e-48 164.5 0.1 3.1e-48 164.2 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DUF5089 PF17002.5 EPS33227.1 - 0.05 13.5 0.1 0.075 12.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5089) ABC_membrane PF00664.23 EPS33228.1 - 1.4e-38 133.2 12.2 1.8e-38 132.8 12.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EPS33228.1 - 5.7e-34 117.6 0.0 1.1e-33 116.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EPS33228.1 - 3.9e-05 23.2 0.0 0.03 13.7 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EPS33228.1 - 4e-05 24.1 0.0 8.6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EPS33228.1 - 0.00048 20.4 0.1 0.0027 18.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 EPS33228.1 - 0.0017 18.2 0.2 0.02 14.7 0.0 2.2 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF2847 PF11009.8 EPS33228.1 - 0.0055 16.6 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2847) AAA_29 PF13555.6 EPS33228.1 - 0.0095 15.7 0.1 0.024 14.4 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_14 PF13173.6 EPS33228.1 - 0.01 15.9 0.0 0.45 10.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EPS33228.1 - 0.011 16.2 0.0 0.035 14.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 EPS33228.1 - 0.014 15.1 0.0 0.034 13.8 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain Rad17 PF03215.15 EPS33228.1 - 0.038 13.9 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain AAA PF00004.29 EPS33228.1 - 0.039 14.4 0.0 0.25 11.7 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EPS33228.1 - 0.043 13.5 0.2 0.26 11.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EPS33228.1 - 0.051 13.3 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EPS33228.1 - 0.059 13.3 0.0 0.33 10.9 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase ATP-synt_ab PF00006.25 EPS33228.1 - 0.083 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.14 EPS33228.1 - 0.088 12.8 0.0 0.33 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EPS33228.1 - 0.09 13.0 0.0 0.43 10.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EPS33228.1 - 0.13 12.5 1.8 2 8.7 0.4 3.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit MFS_1 PF07690.16 EPS33230.1 - 9e-31 107.1 58.6 3.7e-25 88.6 33.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Pex14_N PF04695.13 EPS33230.1 - 0.067 13.8 0.2 0.13 12.9 0.2 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Kinesin PF00225.23 EPS33231.1 - 8e-81 271.5 0.7 8e-81 271.5 0.7 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EPS33231.1 - 2.6e-21 76.1 0.0 5.9e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding HHH PF00633.23 EPS33231.1 - 6.2e-05 22.7 0.3 0.042 13.7 0.0 3.6 3 0 0 3 3 3 1 Helix-hairpin-helix motif HHH_5 PF14520.6 EPS33231.1 - 0.0041 17.7 0.0 1.2 9.8 0.0 2.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_3 PF12836.7 EPS33231.1 - 0.06 13.6 0.2 1.4 9.3 0.0 2.9 3 0 0 3 3 3 0 Helix-hairpin-helix motif DUF3701 PF12482.8 EPS33231.1 - 0.09 12.9 0.0 0.34 11.0 0.0 2.0 1 0 0 1 1 1 0 Phage integrase protein TPR_14 PF13428.6 EPS33231.1 - 0.11 13.4 0.1 0.29 12.1 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat MerR-DNA-bind PF09278.11 EPS33231.1 - 0.27 11.8 6.0 0.66 10.5 3.5 2.7 2 0 0 2 2 2 0 MerR, DNA binding ABC_tran_CTD PF16326.5 EPS33231.1 - 0.37 11.1 3.9 0.38 11.0 1.2 2.4 2 0 0 2 2 2 0 ABC transporter C-terminal domain Sec23_trunk PF04811.15 EPS33232.1 - 9e-71 238.3 0.0 1.5e-70 237.5 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EPS33232.1 - 1.1e-24 86.2 0.2 3.8e-24 84.5 0.0 2.1 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EPS33232.1 - 1.4e-17 64.2 0.0 3.6e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EPS33232.1 - 1.4e-16 60.2 4.7 2.5e-16 59.4 4.7 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EPS33232.1 - 2.2e-10 40.3 0.0 4.1e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 EPS33232.1 - 0.0038 16.6 0.2 0.0094 15.3 0.2 1.6 1 0 0 1 1 1 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain Pkinase PF00069.25 EPS33234.1 - 1.5e-67 227.8 0.0 1.8e-67 227.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS33234.1 - 3.2e-32 111.8 0.0 4.1e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EPS33234.1 - 0.00016 21.1 0.2 0.00025 20.5 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EPS33234.1 - 0.0038 16.2 0.1 0.0058 15.6 0.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EPS33234.1 - 0.011 15.0 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 EPS33234.1 - 0.03 14.2 0.3 0.094 12.6 0.3 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EPS33234.1 - 0.083 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 HEM4 PF02602.15 EPS33235.1 - 1.8e-35 122.4 0.0 7.7e-18 64.7 0.0 3.2 2 1 0 2 2 2 2 Uroporphyrinogen-III synthase HemD NmrA PF05368.13 EPS33236.1 - 3.8e-17 62.6 0.0 5.1e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EPS33236.1 - 2.3e-15 56.7 0.0 4.1e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EPS33236.1 - 1.1e-14 54.8 0.0 1.7e-14 54.1 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EPS33236.1 - 2.3e-11 43.2 0.1 4.1e-11 42.4 0.1 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EPS33236.1 - 1e-09 38.2 0.2 7.4e-09 35.5 0.1 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EPS33236.1 - 9.2e-08 31.5 0.0 2.1e-06 27.1 0.0 2.4 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 EPS33236.1 - 9.3e-05 22.0 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 EPS33236.1 - 0.00052 19.3 0.2 0.052 12.7 0.0 2.8 1 1 2 3 3 3 1 Male sterility protein Polysacc_synt_2 PF02719.15 EPS33236.1 - 0.0022 17.2 0.0 0.0032 16.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short_C2 PF13561.6 EPS33236.1 - 0.0062 16.1 0.0 0.0094 15.5 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPS33236.1 - 0.018 15.0 0.0 3.4 7.5 0.0 2.4 2 0 0 2 2 2 0 KR domain FMO-like PF00743.19 EPS33237.1 - 1.8e-39 135.6 0.0 1e-29 103.4 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EPS33237.1 - 2.9e-16 59.6 0.0 1.1e-15 57.7 0.0 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EPS33237.1 - 4.9e-12 45.7 0.0 1.2e-11 44.4 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EPS33237.1 - 7.1e-11 41.8 0.0 1.1e-09 37.9 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EPS33237.1 - 4.2e-05 23.6 0.0 0.0004 20.4 0.0 2.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 EPS33237.1 - 0.00013 21.7 0.1 0.14 11.7 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EPS33237.1 - 0.0033 17.6 0.0 0.0087 16.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 EPS33237.1 - 0.046 14.2 0.0 5.4 7.5 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding Fer4_8 PF13183.6 EPS33237.1 - 0.23 11.9 1.2 0.42 11.1 0.1 1.9 2 0 0 2 2 2 0 4Fe-4S dicluster domain HIT PF01230.23 EPS33238.1 - 2.6e-22 79.4 0.0 4.2e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EPS33238.1 - 1.4e-11 44.9 0.0 2.5e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EPS33238.1 - 0.00084 19.2 0.0 0.0013 18.6 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CRAL_TRIO PF00650.20 EPS33239.1 - 5.9e-46 156.1 0.0 9.2e-46 155.5 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EPS33239.1 - 4.1e-15 55.7 1.9 7.9e-15 54.8 0.4 2.3 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EPS33239.1 - 1.1e-07 32.1 0.0 2.4e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DASH_Dam1 PF08653.10 EPS33240.1 - 2.9e-29 100.6 2.4 3.9e-29 100.2 2.4 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 UCH PF00443.29 EPS33242.1 - 2.2e-46 158.5 2.2 2.7e-46 158.2 2.2 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EPS33242.1 - 1.2e-15 58.0 7.4 2.8e-14 53.5 7.4 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EPS33242.1 - 0.00025 21.3 1.7 0.00025 21.3 1.7 3.4 3 1 1 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein Ribosomal_S27e PF01667.17 EPS33242.1 - 6 6.7 13.2 0.76 9.5 1.8 3.7 4 0 0 4 4 4 0 Ribosomal protein S27 PHD_3 PF13922.6 EPS33242.1 - 9 6.8 13.8 0.78 10.2 0.1 3.3 4 1 0 4 4 4 0 PHD domain of transcriptional enhancer, Asx Ribosomal_S14 PF00253.21 EPS33243.1 - 8.7e-15 54.2 5.0 9.5e-15 54.1 5.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Ytp1 PF10355.9 EPS33245.1 - 6.7e-117 389.6 9.7 1.2e-116 388.8 9.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 EPS33245.1 - 2.8e-35 120.2 13.2 3.3e-33 113.6 5.6 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF2427) TetR_C_30 PF17939.1 EPS33245.1 - 0.017 15.4 0.2 11 6.3 0.0 2.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DLH PF01738.18 EPS33247.1 - 8.7e-33 113.7 0.1 9.9e-33 113.5 0.1 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 EPS33247.1 - 0.002 17.8 0.0 0.0034 17.1 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Rhomboid PF01694.22 EPS33248.1 - 1.6e-14 54.1 6.8 1.6e-14 54.1 6.8 1.4 2 0 0 2 2 2 1 Rhomboid family Gaa1 PF04114.14 EPS33249.1 - 1.4e-181 604.9 4.5 1.8e-181 604.6 4.5 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component PCI PF01399.27 EPS33250.1 - 7.9e-10 39.2 0.0 1.5e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 PCI domain Rpn9_C PF18261.1 EPS33250.1 - 0.00016 21.2 0.8 0.00032 20.2 0.8 1.5 1 0 0 1 1 1 1 Rpn9 C-terminal helix Methyltransf_11 PF08241.12 EPS33250.1 - 0.12 13.1 0.2 8.2 7.2 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 EPS33251.1 - 2.1e-16 60.2 0.1 3.1e-16 59.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPS33251.1 - 4.3e-14 53.0 0.0 1e-13 51.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPS33251.1 - 3.7e-12 46.3 0.0 5.5e-12 45.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS33251.1 - 4.6e-12 46.4 0.0 1.1e-11 45.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPS33251.1 - 2.4e-11 44.3 0.0 5e-11 43.2 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPS33251.1 - 6.5e-11 42.0 0.0 2.3e-10 40.2 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_15 PF09445.10 EPS33251.1 - 0.012 15.1 0.0 0.019 14.5 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Pox_MCEL PF03291.16 EPS33251.1 - 0.015 14.4 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 mRNA capping enzyme tRNA_U5-meth_tr PF05958.11 EPS33251.1 - 0.028 13.4 0.0 0.041 12.9 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase MTS PF05175.14 EPS33251.1 - 0.03 13.9 0.0 0.064 12.8 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain RrnaAD PF00398.20 EPS33251.1 - 0.094 11.8 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase NodS PF05401.11 EPS33251.1 - 0.2 11.2 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Romo1 PF10247.9 EPS33252.1 - 0.003 17.9 0.2 0.15 12.5 0.0 2.2 2 0 0 2 2 2 2 Reactive mitochondrial oxygen species modulator 1 Peptidase_M20 PF01546.28 EPS33253.1 - 4.8e-29 101.5 0.2 7e-29 101.0 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EPS33253.1 - 0.00017 21.5 0.0 0.00029 20.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain S10_plectin PF03501.15 EPS33254.1 - 2.1e-42 143.1 0.1 2.7e-42 142.8 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Rio2_N PF09202.11 EPS33254.1 - 0.19 12.0 0.3 0.33 11.2 0.1 1.5 2 0 0 2 2 2 0 Rio2, N-terminal Sde2_N_Ubi PF13019.6 EPS33255.1 - 3.1e-66 222.2 0.3 3.1e-66 222.2 0.3 1.6 2 0 0 2 2 2 1 Silencing defective 2 N-terminal ubiquitin domain DUF2407 PF10302.9 EPS33255.1 - 0.025 15.2 1.4 6 7.5 0.5 2.6 1 1 1 2 2 2 0 DUF2407 ubiquitin-like domain Rotamase_2 PF13145.6 EPS33255.1 - 1.4 9.8 5.5 0.23 12.3 1.5 1.7 2 0 0 2 2 2 0 PPIC-type PPIASE domain MMR_HSR1 PF01926.23 EPS33256.1 - 2.9e-06 27.3 0.0 0.032 14.3 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase ATPase-cat_bd PF12156.8 EPS33256.1 - 0.008 16.9 0.0 0.022 15.5 0.0 1.7 1 0 0 1 1 1 1 Putative metal-binding domain of cation transport ATPase Dynamin_N PF00350.23 EPS33256.1 - 0.0098 16.0 0.2 0.92 9.5 0.1 2.6 1 1 1 2 2 2 1 Dynamin family CENP-B_dimeris PF09026.10 EPS33256.1 - 0.085 13.3 0.0 0.17 12.3 0.0 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RsgA_GTPase PF03193.16 EPS33256.1 - 0.13 12.2 0.0 0.41 10.5 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase Septin PF00735.18 EPS33256.1 - 0.15 11.3 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Septin Nod_GRP PF07806.11 EPS33256.1 - 0.46 10.4 2.5 1 9.2 2.5 1.5 1 0 0 1 1 1 0 Nodule-specific GRP repeat tRNA-synt_1 PF00133.22 EPS33257.1 - 2.2e-34 118.7 0.0 1.5e-23 83.0 0.0 3.1 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EPS33257.1 - 2.9e-16 59.8 0.1 7.3e-16 58.5 0.1 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EPS33257.1 - 1.1e-15 57.3 0.0 4e-10 39.0 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EPS33257.1 - 3.4e-07 29.9 0.0 6.8e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 EPS33257.1 - 0.0061 15.5 0.0 0.29 10.0 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class I (K) L51_S25_CI-B8 PF05047.16 EPS33258.1 - 2.9e-15 55.9 0.0 4.4e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain NosL PF05573.12 EPS33258.1 - 0.15 12.4 0.0 0.24 11.8 0.0 1.2 1 0 0 1 1 1 0 NosL DUF1751 PF08551.10 EPS33259.1 - 4.2e-29 101.0 1.9 9.4e-29 99.9 1.9 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 EPS33259.1 - 0.00014 21.9 7.7 0.00028 20.9 7.7 1.5 1 1 0 1 1 1 1 Rhomboid family LisH PF08513.11 EPS33261.1 - 1.7e-06 27.7 0.4 4.5e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 LisH WD40 PF00400.32 EPS33261.1 - 0.00013 22.7 4.8 33 5.6 0.0 6.3 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS33261.1 - 0.041 14.2 0.1 25 5.3 0.0 3.7 2 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EPS33261.1 - 0.13 11.2 0.1 1.1 8.2 0.0 2.1 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EPS33261.1 - 0.22 11.4 0.0 0.64 9.9 0.0 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A TSKS PF15358.6 EPS33262.1 - 0.00067 18.2 0.5 0.0009 17.7 0.5 1.2 1 0 0 1 1 1 1 Testis-specific serine kinase substrate DLP_helical PF18709.1 EPS33262.1 - 0.023 13.9 0.5 0.038 13.2 0.5 1.2 1 0 0 1 1 1 0 Dynamin-like helical domain PKcGMP_CC PF16808.5 EPS33262.1 - 0.038 13.8 0.6 0.095 12.6 0.4 1.8 1 1 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase TPR_MLP1_2 PF07926.12 EPS33262.1 - 0.4 10.7 5.6 0.54 10.3 2.9 2.4 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Syntaxin-6_N PF09177.11 EPS33262.1 - 0.85 10.2 5.2 0.97 10.0 1.1 2.7 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Jnk-SapK_ap_N PF09744.9 EPS33262.1 - 3.1 8.0 9.3 0.46 10.7 4.0 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF2203 PF09969.9 EPS33262.1 - 3.2 8.5 7.4 0.26 12.0 0.7 2.5 4 0 0 4 4 4 0 Uncharacterized conserved protein (DUF2203) bZIP_1 PF00170.21 EPS33262.1 - 3.5 7.8 13.4 0.054 13.6 2.7 2.8 2 1 0 2 2 2 0 bZIP transcription factor Chorismate_bind PF00425.18 EPS33263.1 - 5.1e-90 301.5 0.0 8.2e-90 300.8 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 EPS33263.1 - 3e-27 95.6 0.0 1.7e-23 83.4 0.0 3.1 3 1 0 3 3 3 2 Anthranilate synthase component I, N terminal region PCuAC PF04314.13 EPS33263.1 - 0.079 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Copper chaperone PCu(A)C Hexokinase_1 PF00349.21 EPS33264.1 - 9.7e-50 169.2 0.0 1.3e-49 168.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 EPS33264.1 - 1e-39 136.4 0.0 1.6e-39 135.8 0.0 1.3 1 0 0 1 1 1 1 Hexokinase BolA PF01722.18 EPS33265.1 - 1.3e-18 67.0 0.0 2.4e-18 66.2 0.0 1.4 1 1 0 1 1 1 1 BolA-like protein NIF3 PF01784.18 EPS33266.1 - 8.6e-58 195.8 0.0 1.1e-57 195.5 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) HoxA13_N PF12284.8 EPS33266.1 - 0.96 10.1 5.1 0.31 11.7 1.3 2.0 2 1 0 2 2 2 0 Hox protein A13 N terminal ENTH PF01417.20 EPS33267.1 - 4.1e-47 159.3 0.0 6.8e-47 158.6 0.0 1.4 1 0 0 1 1 1 1 ENTH domain UIM PF02809.20 EPS33267.1 - 5.2e-05 22.9 5.9 0.00061 19.5 2.2 2.7 2 0 0 2 2 2 1 Ubiquitin interaction motif ANTH PF07651.16 EPS33267.1 - 0.00093 18.3 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 ANTH domain DUF1720 PF08226.11 EPS33267.1 - 0.011 16.1 18.0 0.011 16.1 18.0 5.6 1 1 3 4 4 4 0 Domain of unknown function (DUF1720) DUF4264 PF14084.6 EPS33267.1 - 0.05 13.2 0.0 0.13 12.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4264) Redoxin PF08534.10 EPS33268.1 - 2.2e-26 92.4 0.0 2.5e-26 92.1 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EPS33268.1 - 7.1e-07 29.2 0.0 9.5e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family HSF_DNA-bind PF00447.17 EPS33270.1 - 1.4e-27 96.1 0.9 1.4e-27 96.1 0.9 1.8 2 0 0 2 2 2 1 HSF-type DNA-binding Response_reg PF00072.24 EPS33270.1 - 1.6e-22 79.8 0.0 3e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Clusterin PF01093.17 EPS33270.1 - 0.0069 15.5 1.7 0.01 14.9 1.7 1.2 1 0 0 1 1 1 1 Clusterin SlyX PF04102.12 EPS33270.1 - 0.083 13.5 6.0 0.29 11.8 6.0 2.0 1 0 0 1 1 1 0 SlyX W2 PF02020.18 EPS33271.1 - 2.7e-19 69.1 7.2 2.7e-19 69.1 7.2 3.0 2 1 1 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 EPS33271.1 - 3.9e-13 48.6 12.0 7.2e-05 22.4 1.7 4.2 1 1 2 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EPS33271.1 - 1.4e-07 31.2 6.9 0.0014 18.4 0.9 3.5 2 1 1 3 3 3 3 Hexapeptide repeat of succinyl-transferase NTP_transferase PF00483.23 EPS33271.1 - 2e-07 30.9 0.0 4.4e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EPS33271.1 - 0.0034 17.8 0.0 0.0064 16.9 0.0 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF4954 PF16314.5 EPS33271.1 - 0.0057 14.8 0.6 0.052 11.7 0.0 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4954) UPF0181 PF03701.14 EPS33271.1 - 0.014 15.0 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0181) Lipoprotein_10 PF03202.13 EPS33271.1 - 0.15 12.5 0.6 0.35 11.3 0.6 1.6 1 0 0 1 1 1 0 Putative mycoplasma lipoprotein, C-terminal region IBR PF01485.21 EPS33272.1 - 1.2e-22 79.9 44.6 2.3e-12 47.0 4.5 4.4 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 EPS33272.1 - 2.8e-07 30.3 35.2 9.2e-05 22.2 3.9 4.5 3 1 1 4 4 4 3 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EPS33272.1 - 0.00022 21.5 42.0 0.00028 21.2 6.1 3.9 3 1 0 3 3 3 3 Ring finger domain zf-C3HC4_2 PF13923.6 EPS33272.1 - 0.00035 20.3 4.6 0.00035 20.3 4.6 4.9 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) UN_NPL4 PF11543.8 EPS33272.1 - 0.016 15.7 0.0 0.029 14.8 0.0 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 zf-RING_UBOX PF13445.6 EPS33272.1 - 0.023 14.7 3.3 0.023 14.7 3.3 3.9 3 1 0 3 3 3 0 RING-type zinc-finger Trp_syntA PF00290.20 EPS33272.1 - 0.17 10.7 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Tryptophan synthase alpha chain Mito_carr PF00153.27 EPS33273.1 - 2.6e-63 210.0 6.6 9.3e-23 80.0 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein AAA PF00004.29 EPS33274.1 - 2.1e-37 128.5 0.0 4.7e-37 127.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EPS33274.1 - 5.7e-09 35.8 0.1 3.1e-07 30.3 0.0 3.3 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 EPS33274.1 - 3.9e-08 33.0 0.3 1e-07 31.7 0.0 1.9 2 0 0 2 2 2 1 AAA+ lid domain RuvB_N PF05496.12 EPS33274.1 - 6.5e-05 22.7 0.0 0.00012 21.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EPS33274.1 - 0.00018 21.6 0.0 0.00035 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EPS33274.1 - 0.00035 20.9 0.4 0.00035 20.9 0.4 2.7 3 1 0 3 3 1 1 AAA domain AAA_5 PF07728.14 EPS33274.1 - 0.00062 19.8 0.1 0.0039 17.2 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EPS33274.1 - 0.00091 19.7 1.5 0.003 18.0 0.2 2.5 2 1 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 EPS33274.1 - 0.0019 17.5 0.0 0.0033 16.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 EPS33274.1 - 0.0037 17.0 0.0 0.0067 16.2 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EPS33274.1 - 0.0044 16.4 0.1 0.01 15.2 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EPS33274.1 - 0.021 15.0 0.0 0.055 13.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 EPS33274.1 - 0.021 14.0 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.6 EPS33274.1 - 0.058 13.0 0.0 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EPS33274.1 - 0.065 12.9 0.0 0.2 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EPS33274.1 - 0.092 12.8 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EPS33274.1 - 0.095 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 EPS33274.1 - 0.1 13.1 0.0 0.29 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EPS33274.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.26 EPS33274.1 - 0.17 11.6 0.0 0.38 10.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Esterase_phd PF10503.9 EPS33276.1 - 0.00098 18.7 0.1 0.0019 17.7 0.1 1.6 1 1 0 1 1 1 1 Esterase PHB depolymerase Esterase PF00756.20 EPS33276.1 - 0.0048 16.6 0.0 0.0061 16.2 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 EPS33276.1 - 0.0079 15.7 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Marek_A PF02124.15 EPS33277.1 - 0.09 12.6 0.0 0.29 10.9 0.0 1.7 1 1 0 2 2 2 0 Marek's disease glycoprotein A COG6 PF06419.11 EPS33279.1 - 2.3e-212 706.7 0.0 2.6e-212 706.5 0.0 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 Cep57_CLD PF14073.6 EPS33279.1 - 0.011 15.8 0.6 0.022 14.8 0.6 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 DUF948 PF06103.11 EPS33279.1 - 0.017 15.4 0.8 0.038 14.2 0.2 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF4698 PF15769.5 EPS33279.1 - 0.026 13.6 0.6 0.042 12.9 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) Seryl_tRNA_N PF02403.22 EPS33279.1 - 0.045 14.0 1.9 0.3 11.3 1.4 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Tnp_DNA_bind PF14706.6 EPS33279.1 - 0.11 12.3 0.1 0.34 10.8 0.1 1.9 1 0 0 1 1 1 0 Transposase DNA-binding DUF1043 PF06295.12 EPS33279.1 - 0.22 11.6 4.9 1.1 9.3 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1043) COG2 PF06148.11 EPS33279.1 - 0.59 10.2 5.0 0.31 11.1 1.0 2.6 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 YabA PF06156.13 EPS33279.1 - 9.4 6.9 6.1 8.5 7.1 0.4 3.0 2 1 0 3 3 3 0 Initiation control protein YabA FapA PF03961.13 EPS33280.1 - 0.037 12.7 1.5 0.036 12.7 0.4 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A GAS PF13851.6 EPS33280.1 - 0.45 9.8 9.5 1.2 8.5 0.2 2.8 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 EPS33280.1 - 1.9 9.0 17.9 0.69 10.4 7.0 3.0 2 1 1 3 3 3 0 Apg6 coiled-coil region Lzipper-MIP1 PF14389.6 EPS33280.1 - 3.6 8.0 10.9 1.7 9.0 0.3 3.0 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 HSP9_HSP12 PF04119.12 EPS33281.1 - 3.4e-28 97.8 8.2 5.2e-28 97.2 7.4 1.7 2 0 0 2 2 2 1 Heat shock protein 9/12 YtxH PF12732.7 EPS33281.1 - 0.23 12.0 1.8 0.77 10.3 1.8 2.0 1 1 0 1 1 1 0 YtxH-like protein NYN PF01936.18 EPS33282.1 - 0.00031 21.3 0.0 0.0013 19.2 0.0 2.0 1 1 0 1 1 1 1 NYN domain Mog1 PF04603.12 EPS33283.1 - 1.5e-25 90.2 0.0 4e-25 88.8 0.0 1.7 1 1 0 1 1 1 1 Ran-interacting Mog1 protein CPSase_L_D2 PF02786.17 EPS33283.1 - 0.12 11.8 0.1 0.19 11.2 0.1 1.2 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain HdeA PF06411.11 EPS33283.1 - 0.13 12.5 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 HdeA/HdeB family SprT-like PF10263.9 EPS33284.1 - 3.8e-37 126.6 0.6 7.4e-37 125.7 0.6 1.5 1 0 0 1 1 1 1 SprT-like family Zn_ribbon_SprT PF17283.2 EPS33284.1 - 9.6e-11 41.4 6.5 1.8e-10 40.5 6.5 1.5 1 0 0 1 1 1 1 SprT-like zinc ribbon domain DUF4379 PF14311.6 EPS33284.1 - 0.011 16.1 3.5 0.034 14.5 3.5 1.9 1 0 0 1 1 1 0 Probable Zinc-ribbon domain Zn-ribbon_8 PF09723.10 EPS33284.1 - 0.084 13.0 0.8 0.18 12.0 0.8 1.5 1 0 0 1 1 1 0 Zinc ribbon domain Tox-MPTase2 PF15638.6 EPS33284.1 - 0.17 11.6 0.4 0.35 10.6 0.4 1.4 1 0 0 1 1 1 0 Metallopeptidase toxin 2 DUF2072 PF09845.9 EPS33284.1 - 7.8 6.8 6.6 0.75 10.1 0.1 2.7 2 1 0 2 2 2 0 Zn-ribbon containing protein Glucan_synthase PF02364.15 EPS33286.1 - 0 1367.6 0.0 0 1366.7 0.0 1.4 2 0 0 2 2 2 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 EPS33286.1 - 3.9e-43 146.9 0.7 1e-42 145.5 0.7 1.8 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Aminotran_1_2 PF00155.21 EPS33287.1 - 3.5e-35 121.8 0.0 4.3e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EPS33287.1 - 0.011 14.3 0.0 0.025 13.1 0.0 1.5 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Glyco_hydro_17 PF00332.18 EPS33288.1 - 0.00011 21.9 0.0 0.00026 20.7 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 WD40 PF00400.32 EPS33290.1 - 9.3e-08 32.6 0.0 3 8.9 0.0 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF3_subunit PF08597.10 EPS33290.1 - 0.19 11.6 4.5 0.36 10.7 4.5 1.5 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Zn_clus PF00172.18 EPS33291.1 - 9.5e-06 25.6 8.5 9.5e-06 25.6 8.5 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPS33291.1 - 0.00021 20.5 0.5 0.00052 19.1 0.5 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain RasGAP PF00616.19 EPS33292.1 - 3.4e-31 108.6 0.0 2.5e-21 76.4 0.0 2.7 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 EPS33292.1 - 1.7e-08 34.6 0.1 8.6e-08 32.4 0.1 2.2 1 1 0 1 1 1 1 C2 domain APG9 PF04109.16 EPS33293.1 - 5.9e-209 695.0 14.5 6.8e-209 694.8 14.5 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 Glyco_hydro_47 PF01532.20 EPS33294.1 - 4.2e-190 632.5 0.0 4.9e-190 632.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 4HB_MCP_1 PF12729.7 EPS33294.1 - 0.031 13.8 0.1 0.074 12.6 0.0 1.6 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction DUF2013 PF09431.10 EPS33295.1 - 4.2e-51 172.7 1.9 4.2e-51 172.7 1.9 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) RE_LlaJI PF09563.10 EPS33295.1 - 0.031 13.4 0.2 0.05 12.8 0.2 1.2 1 0 0 1 1 1 0 LlaJI restriction endonuclease COQ9 PF08511.11 EPS33296.1 - 9.8e-23 79.7 0.0 1.8e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 COQ9 RRM_1 PF00076.22 EPS33297.1 - 5.3e-55 183.1 0.0 1.4e-17 63.2 0.0 3.5 3 1 1 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EPS33297.1 - 5.3e-05 22.8 0.0 0.02 14.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EPS33297.1 - 0.00049 20.1 0.0 1.7 8.8 0.0 3.4 3 1 0 3 3 3 2 RNA binding motif PknH_C PF14032.6 EPS33297.1 - 0.0038 17.1 0.4 9.3 6.0 0.2 3.1 3 0 0 3 3 3 1 PknH-like extracellular domain RRM_Rrp7 PF17799.1 EPS33297.1 - 0.069 13.0 0.0 7.1 6.4 0.0 2.9 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain ATP-grasp_2 PF08442.10 EPS33297.1 - 0.08 12.5 0.0 0.54 9.8 0.0 2.2 3 0 0 3 3 3 0 ATP-grasp domain RRM_occluded PF16842.5 EPS33297.1 - 0.083 12.8 0.0 17 5.4 0.0 3.4 3 1 0 3 3 3 0 Occluded RNA-recognition motif DUF3343 PF11823.8 EPS33297.1 - 0.2 11.1 0.0 0.45 10.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3343) CAF-1_p150 PF11600.8 EPS33300.1 - 0.0077 15.9 14.9 0.0096 15.6 14.9 1.1 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal PH PF00169.29 EPS33301.1 - 1.8e-06 28.4 0.1 3.9e-06 27.3 0.1 1.6 1 0 0 1 1 1 1 PH domain DUF5344 PF17279.2 EPS33301.1 - 0.009 16.6 1.0 7.5 7.2 0.0 2.7 2 0 0 2 2 2 2 Family of unknown function (DUF5344) Tim17 PF02466.19 EPS33302.1 - 2.8e-08 34.1 5.5 6e-08 33.0 4.9 1.8 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family RPT PF13446.6 EPS33303.1 - 1.1e-50 169.4 2.1 2.2e-18 65.9 0.0 4.6 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH PF00443.29 EPS33303.1 - 3.1e-47 161.2 0.0 9.2e-47 159.7 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EPS33303.1 - 3.1e-06 27.0 0.1 0.00018 21.2 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Microvir_H PF04687.12 EPS33303.1 - 0.15 11.4 0.2 0.27 10.6 0.2 1.3 1 0 0 1 1 1 0 Microvirus H protein (pilot protein) Baculo_LEF5_C PF11792.8 EPS33303.1 - 0.64 9.7 6.0 2.6 7.8 6.0 2.1 1 1 0 1 1 1 0 Baculoviridae late expression factor 5 C-terminal domain CoA_trans PF01144.23 EPS33304.1 - 5.2e-104 346.4 1.0 1.3e-62 211.0 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase DUF2370 PF10176.9 EPS33306.1 - 3.1e-90 301.8 0.0 4.7e-90 301.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) Pkinase PF00069.25 EPS33308.1 - 8.3e-68 228.6 0.0 1.1e-67 228.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS33308.1 - 4.1e-31 108.2 0.0 6e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EPS33308.1 - 0.012 14.6 0.0 0.022 13.7 0.0 1.5 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EPS33308.1 - 0.045 13.1 0.0 0.092 12.1 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EPS33308.1 - 0.06 13.3 1.2 0.17 11.8 0.0 2.2 3 0 0 3 3 3 0 Phosphotransferase enzyme family tRNA-synt_2b PF00587.25 EPS33309.1 - 7.2e-29 101.0 0.0 1.9e-26 93.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EPS33309.1 - 1e-17 64.0 0.3 2.2e-17 63.0 0.3 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 EPS33309.1 - 9.5e-15 54.4 0.0 1.8e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 EPS33309.1 - 1.3e-06 28.3 0.0 3.2e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 TGS domain Gar1 PF04410.14 EPS33310.1 - 4.8e-39 133.6 0.0 5.8e-39 133.3 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region CDP-OH_P_transf PF01066.21 EPS33311.1 - 1.4e-12 48.2 0.1 1.4e-12 48.2 0.1 2.2 3 0 0 3 3 3 1 CDP-alcohol phosphatidyltransferase MACPF PF01823.19 EPS33312.1 - 1e-07 32.3 0.1 1.9e-07 31.4 0.1 1.5 1 0 0 1 1 1 1 MAC/Perforin domain PGM_PMM_I PF02878.16 EPS33312.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I WSC PF01822.19 EPS33316.1 - 3.3e-14 52.8 8.8 7.7e-14 51.6 8.8 1.7 1 0 0 1 1 1 1 WSC domain SKG6 PF08693.10 EPS33316.1 - 2.2e-08 33.4 1.0 4.3e-08 32.4 1.0 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rab5ip PF07019.12 EPS33316.1 - 0.0016 19.0 0.7 0.0031 18.1 0.7 1.5 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Gram_pos_anchor PF00746.21 EPS33316.1 - 0.016 15.1 0.8 0.016 15.1 0.8 2.4 2 1 0 2 2 2 0 LPXTG cell wall anchor motif DUF5305 PF17231.2 EPS33316.1 - 0.13 11.7 0.1 0.21 11.0 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5305) Serglycin PF04360.12 EPS33316.1 - 0.16 11.9 4.8 0.37 10.7 4.8 1.7 1 0 0 1 1 1 0 Serglycin DUF2627 PF11118.8 EPS33316.1 - 0.16 12.6 0.0 0.28 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) MGC-24 PF05283.11 EPS33316.1 - 3 8.3 13.1 8.6 6.8 13.0 1.9 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin AF-4 PF05110.13 EPS33316.1 - 3.9 5.5 7.7 4.6 5.2 7.7 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein zf-C2H2 PF00096.26 EPS33320.1 - 9.5e-05 22.7 17.6 0.0033 17.8 5.2 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPS33320.1 - 0.0067 17.2 12.6 0.12 13.2 4.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger FOXP-CC PF16159.5 EPS33320.1 - 0.13 12.9 5.9 2.6 8.7 0.9 2.4 1 1 1 2 2 2 0 FOXP coiled-coil domain CHORD PF04968.12 EPS33320.1 - 0.42 11.4 6.6 6.4 7.6 0.8 2.4 1 1 1 2 2 2 0 CHORD PhnA_Zn_Ribbon PF08274.12 EPS33321.1 - 0.15 12.0 1.5 0.87 9.6 0.3 2.2 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Ifi-6-16 PF06140.13 EPS33324.1 - 2.8e-07 30.4 7.5 4e-07 29.8 7.5 1.3 1 0 0 1 1 1 1 Interferon-induced 6-16 family Ifi-6-16 PF06140.13 EPS33325.1 - 3.7e-05 23.5 13.7 6.4e-05 22.8 13.7 1.4 1 0 0 1 1 1 1 Interferon-induced 6-16 family Hum_adeno_E3A PF05393.11 EPS33325.1 - 0.07 13.1 0.1 0.16 12.0 0.1 1.6 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein MFS_1 PF07690.16 EPS33330.1 - 7.9e-45 153.3 33.9 7.9e-45 153.3 33.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS33330.1 - 1.5e-09 37.2 9.5 1.5e-09 37.2 9.5 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_4 PF06779.14 EPS33330.1 - 0.00013 21.4 3.8 0.00013 21.4 3.8 2.9 3 0 0 3 3 3 2 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 EPS33330.1 - 0.46 8.7 14.6 0.47 8.7 0.5 3.6 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family TPMT PF05724.11 EPS33331.1 - 2.4e-25 89.5 0.0 7.6e-25 87.8 0.0 1.7 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_11 PF08241.12 EPS33331.1 - 4e-06 27.4 0.0 6.4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPS33331.1 - 3e-05 24.6 0.0 4.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPS33331.1 - 0.0011 18.9 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPS33331.1 - 0.011 15.5 0.0 0.021 14.6 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EPS33331.1 - 0.049 14.4 0.0 0.093 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain OTU PF02338.19 EPS33332.1 - 1.7e-21 77.1 0.3 2.6e-20 73.2 0.3 2.4 1 1 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EPS33332.1 - 6e-06 25.9 1.2 0.00033 20.2 0.0 2.7 3 0 0 3 3 3 2 Peptidase C65 Otubain Hamartin PF04388.12 EPS33332.1 - 1.5 7.4 10.1 1.6 7.3 10.1 1.1 1 0 0 1 1 1 0 Hamartin protein adh_short_C2 PF13561.6 EPS33333.1 - 1.7e-47 161.9 0.0 2e-47 161.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPS33333.1 - 3.2e-44 150.7 0.0 4.3e-44 150.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPS33333.1 - 6.5e-08 32.7 0.0 1.2e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 EPS33333.1 - 0.11 13.1 0.1 0.26 11.9 0.1 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Trehalase PF01204.18 EPS33334.1 - 1.3e-194 647.8 0.1 1.5e-194 647.6 0.1 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 EPS33334.1 - 1.5e-16 59.8 1.0 2.4e-16 59.1 1.0 1.3 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain ICL PF00463.21 EPS33335.1 - 4e-302 1002.4 3.9 4.5e-302 1002.2 3.9 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 EPS33335.1 - 5.7e-12 45.6 0.1 1.5e-11 44.2 0.1 1.7 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase STb_secrete PF09075.10 EPS33335.1 - 0.049 13.7 0.1 0.12 12.5 0.1 1.6 1 0 0 1 1 1 0 Heat-stable enterotoxin B, secretory Aldedh PF00171.22 EPS33336.1 - 8.3e-79 265.2 0.0 1e-78 264.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Aa_trans PF01490.18 EPS33338.1 - 3.7e-20 72.0 34.7 4.5e-20 71.7 34.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Adap_comp_sub PF00928.21 EPS33339.1 - 5.2e-59 199.8 0.0 4.4e-58 196.7 0.0 2.0 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EPS33339.1 - 0.00063 19.7 0.2 0.0011 19.0 0.2 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF2201 PF09967.9 EPS33339.1 - 0.12 12.5 0.2 0.27 11.4 0.0 1.6 2 0 0 2 2 2 0 VWA-like domain (DUF2201) PROL5-SMR PF15621.6 EPS33339.1 - 3.3 8.3 10.9 3.9 8.1 4.9 2.8 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family DUF4536 PF15055.6 EPS33340.1 - 7.7e-06 26.1 5.1 3.2e-05 24.1 5.2 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4536) DUF4588 PF15251.6 EPS33341.1 - 1.2e-05 25.2 0.8 2.3e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4588) SNF2_N PF00176.23 EPS33342.1 - 3.2e-73 246.5 0.0 5.8e-73 245.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 EPS33342.1 - 1.5e-43 147.4 1.5 1.5e-43 147.4 1.5 2.3 2 0 0 2 2 2 1 SLIDE HAND PF09110.11 EPS33342.1 - 3.7e-35 121.0 2.1 3.7e-35 121.0 2.1 3.7 4 0 0 4 4 3 1 HAND Helicase_C PF00271.31 EPS33342.1 - 1.1e-18 67.6 0.0 8.6e-18 64.7 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPS33342.1 - 2.8e-10 40.5 0.0 1.7e-09 37.9 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 EPS33342.1 - 3.8e-06 26.3 0.0 1.2e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 EPS33342.1 - 0.00084 19.2 0.0 0.0021 17.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EPS33342.1 - 0.0025 17.5 0.0 0.0066 16.1 0.0 1.7 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DEAD_2 PF06733.15 EPS33342.1 - 0.019 14.6 0.0 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 DEAD_2 AAA_14 PF13173.6 EPS33342.1 - 0.028 14.4 0.0 0.13 12.3 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EPS33342.1 - 0.036 14.4 0.2 0.53 10.6 0.1 3.0 3 0 0 3 3 3 0 AAA domain Myb_DNA-binding PF00249.31 EPS33342.1 - 0.051 13.8 0.0 3.1 8.1 0.0 2.8 2 0 0 2 2 2 0 Myb-like DNA-binding domain Tn7_Tnp_TnsA_C PF08721.11 EPS33342.1 - 0.11 13.2 0.1 1.4 9.6 0.0 2.9 1 1 1 2 2 2 0 TnsA endonuclease C terminal Asp PF00026.23 EPS33343.1 - 8.1e-69 232.4 5.2 9.6e-69 232.2 5.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EPS33343.1 - 4.3e-14 53.1 2.2 4.2e-10 40.2 1.9 3.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EPS33343.1 - 0.048 14.3 1.8 12 6.7 0.5 3.2 2 1 0 2 2 2 0 Aspartyl protease OCRE PF17780.1 EPS33343.1 - 0.058 13.4 0.3 0.24 11.5 0.3 2.0 1 0 0 1 1 1 0 OCRE domain DUF4988 PF16378.5 EPS33343.1 - 0.16 11.6 1.2 2.7 7.6 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function ADH_zinc_N PF00107.26 EPS33344.1 - 1e-23 83.7 0.5 1.8e-23 82.9 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPS33344.1 - 2.3e-18 66.1 0.7 3.3e-18 65.6 0.7 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 EPS33344.1 - 2.1e-08 33.9 0.2 4.1e-08 33.0 0.2 1.5 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EPS33344.1 - 2.2e-08 35.3 0.1 4.5e-08 34.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EPS33344.1 - 0.00092 18.6 0.1 0.002 17.4 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain SpoU_methylase PF00588.19 EPS33345.1 - 7.2e-25 87.8 0.2 9.7e-24 84.2 0.2 2.1 1 1 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 EPS33345.1 - 1.6e-07 31.5 0.0 3.7e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding zf-PHD-like PF15446.6 EPS33346.1 - 1.6e-60 203.6 12.6 3.3e-60 202.5 12.6 1.6 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.23 EPS33346.1 - 4.1e-52 177.0 0.1 7.3e-52 176.2 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-CCCH_6 PF18585.1 EPS33346.1 - 2.6e-25 88.1 0.4 8e-25 86.5 0.4 1.9 1 0 0 1 1 1 1 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Helicase_C PF00271.31 EPS33346.1 - 2.2e-19 69.9 0.0 5.3e-19 68.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.8 EPS33346.1 - 1.5e-09 37.4 1.1 5.8e-09 35.5 1.1 1.8 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 PHD PF00628.29 EPS33346.1 - 8e-08 32.1 20.6 8.2e-07 28.8 4.4 3.3 3 1 0 3 3 3 2 PHD-finger Chromo PF00385.24 EPS33346.1 - 2.2e-05 24.3 3.8 0.091 12.7 0.4 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF1087 PF06465.13 EPS33346.1 - 3.5e-05 23.8 2.0 0.00013 21.9 2.0 2.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1087) ResIII PF04851.15 EPS33346.1 - 6.1e-05 23.1 0.0 0.00012 22.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PHD_4 PF16866.5 EPS33346.1 - 0.071 13.2 19.0 0.33 11.1 3.9 3.8 2 2 0 2 2 2 0 PHD-finger Zf_RING PF16744.5 EPS33346.1 - 0.34 11.0 13.2 0.51 10.5 0.9 2.9 2 1 0 2 2 2 0 KIAA1045 RING finger SOG2 PF10428.9 EPS33347.1 - 0.79 8.8 3.7 0.92 8.6 3.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein MRP-S28 PF10213.9 EPS33348.1 - 1.2e-43 148.5 0.3 3.7e-43 147.0 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein Glyco_tran_28_C PF04101.16 EPS33349.1 - 1.6e-21 77.0 0.0 3.1e-21 76.1 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.18 EPS33349.1 - 0.03 13.1 0.1 0.06 12.1 0.1 1.5 1 1 1 2 2 2 0 UDP-glucoronosyl and UDP-glucosyl transferase Actin PF00022.19 EPS33350.1 - 4.4e-126 420.8 0.0 2.7e-125 418.2 0.0 1.8 1 1 0 1 1 1 1 Actin DUF4332 PF14229.6 EPS33350.1 - 0.13 12.5 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) ADH_N PF08240.12 EPS33351.1 - 1e-24 86.5 5.7 1.6e-24 85.9 5.7 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPS33351.1 - 2.7e-15 56.5 0.0 6.6e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EPS33351.1 - 0.00011 21.6 0.1 0.00023 20.6 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 EPS33351.1 - 0.022 14.0 0.0 0.043 13.1 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF3602 PF12223.8 EPS33354.1 - 1.2e-23 83.5 6.8 2e-21 76.4 1.6 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF3602) zf-U1 PF06220.12 EPS33357.1 - 4.8e-16 58.2 2.1 7.3e-16 57.7 2.1 1.3 1 0 0 1 1 1 1 U1 zinc finger TRP PF06011.12 EPS33358.1 - 2.2e-167 557.1 22.4 3.4e-167 556.5 22.4 1.3 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 EPS33358.1 - 3.1e-37 128.0 0.0 5.1e-37 127.3 0.0 1.3 1 0 0 1 1 1 1 ML-like domain Ac76 PF05814.11 EPS33358.1 - 0.0048 16.9 4.7 0.5 10.4 0.1 3.3 2 1 1 3 3 3 2 Orf76 (Ac76) Rab5ip PF07019.12 EPS33358.1 - 0.055 14.1 4.2 0.69 10.6 0.9 3.1 2 0 0 2 2 2 0 Rab5-interacting protein (Rab5ip) OppC_N PF12911.7 EPS33358.1 - 0.24 11.4 7.3 6.5 6.8 0.0 4.1 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C Shisa PF13908.6 EPS33358.1 - 1.3 9.2 3.2 2.1 8.5 0.1 2.5 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.6 EPS33358.1 - 2.5 9.0 5.7 24 5.9 0.1 3.5 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain DEAD PF00270.29 EPS33359.1 - 3.3e-46 157.3 0.1 5.9e-46 156.4 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPS33359.1 - 2e-23 82.9 0.0 8.5e-23 80.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EPS33359.1 - 2.4e-18 66.1 0.2 4.5e-18 65.2 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EPS33359.1 - 0.0006 19.8 0.0 0.0014 18.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EPS33359.1 - 0.00063 19.0 0.0 0.0017 17.6 0.0 1.7 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Nop14 PF04147.12 EPS33359.1 - 1.4 7.0 13.5 1.8 6.7 13.5 1.1 1 0 0 1 1 1 0 Nop14-like family HNF-1_N PF04814.13 EPS33359.1 - 4.5 7.9 7.5 8.4 7.0 7.5 1.3 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Hydrolase PF00702.26 EPS33362.1 - 6.3e-16 59.3 0.0 1.8e-12 48.0 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EPS33362.1 - 1.7e-13 51.0 0.0 2.2e-12 47.5 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EPS33362.1 - 1.3e-07 31.5 0.0 2.7e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like PGP_phosphatase PF09419.10 EPS33362.1 - 0.0019 17.8 0.0 0.27 10.8 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial PGP phosphatase HAD PF12710.7 EPS33362.1 - 0.0031 17.9 0.1 0.017 15.5 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EPS33362.1 - 0.081 13.0 0.0 1.7 8.8 0.0 2.4 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase zf-CCHC PF00098.23 EPS33363.1 - 0.0049 16.9 1.9 0.0049 16.9 1.9 4.6 5 0 0 5 5 5 2 Zinc knuckle zf-ribbon_3 PF13248.6 EPS33363.1 - 7.7 6.1 10.4 4 7.0 1.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain ORMDL PF04061.14 EPS33364.1 - 3.6e-59 198.5 3.2 4.3e-59 198.2 3.2 1.1 1 0 0 1 1 1 1 ORMDL family CH PF00307.31 EPS33366.1 - 3.1e-15 56.3 0.0 5.2e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF4677 PF15726.5 EPS33366.1 - 0.37 10.9 2.6 0.46 10.6 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4677) AMP-binding PF00501.28 EPS33367.1 - 3.8e-70 236.6 0.0 5.1e-70 236.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EPS33367.1 - 4e-57 193.3 0.0 5.7e-57 192.8 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 EPS33367.1 - 2.2e-12 47.2 0.0 4.6e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 EPS33367.1 - 1e-09 37.8 0.0 1.6e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EPS33367.1 - 1.3e-09 37.9 0.0 2.4e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.6 EPS33367.1 - 2.8e-05 25.0 0.0 0.00021 22.2 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GDP_Man_Dehyd PF16363.5 EPS33367.1 - 0.0025 17.3 0.0 0.0047 16.4 0.0 1.5 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EPS33367.1 - 0.0068 15.6 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 EPS33367.1 - 0.035 14.6 0.0 0.084 13.3 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 EPS33367.1 - 0.081 12.8 0.0 0.59 10.0 0.0 2.2 1 1 0 1 1 1 0 NAD(P)H-binding KR PF08659.10 EPS33367.1 - 0.084 12.8 0.1 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 KR domain NDUFA12 PF05071.16 EPS33368.1 - 3.1e-12 47.2 5.7 1.3e-11 45.1 5.7 2.1 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Astro_capsid_p PF12226.8 EPS33369.1 - 2.1 7.4 12.4 4.3 6.4 12.4 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Piwi PF02171.17 EPS33372.1 - 6.1e-60 203.0 0.0 9.8e-60 202.3 0.0 1.3 1 0 0 1 1 1 1 Piwi domain ArgoN PF16486.5 EPS33372.1 - 6.2e-11 43.1 0.0 1.3e-10 42.0 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL1 PF08699.10 EPS33372.1 - 8e-10 38.2 0.1 2.5e-09 36.7 0.1 1.9 1 0 0 1 1 1 1 Argonaute linker 1 domain PAZ PF02170.22 EPS33372.1 - 1.5e-09 37.8 0.0 2e-08 34.1 0.0 2.3 2 0 0 2 2 2 1 PAZ domain ArgoL2 PF16488.5 EPS33372.1 - 2.9e-05 24.3 0.0 8.4e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 EPS33372.1 - 6.6e-05 23.1 0.1 0.00015 22.0 0.1 1.7 1 0 0 1 1 1 1 Mid domain of argonaute EMP24_GP25L PF01105.24 EPS33374.1 - 2.3e-40 138.5 0.0 2.7e-40 138.2 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.12 EPS33374.1 - 0.082 11.1 0.2 0.11 10.7 0.2 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Sdh5 PF03937.16 EPS33375.1 - 4.5e-24 84.2 0.1 1.5e-23 82.5 0.1 1.8 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase WD40 PF00400.32 EPS33376.1 - 1.7e-46 155.2 23.2 1.3e-09 38.5 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS33376.1 - 1.7e-09 37.8 0.5 0.05 13.9 0.0 4.5 2 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EPS33376.1 - 2.9e-05 22.9 4.8 0.13 10.9 0.1 4.6 2 1 2 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EPS33376.1 - 0.0013 17.7 0.1 3.3 6.6 0.0 3.8 2 2 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 EPS33376.1 - 0.0032 16.0 0.0 0.93 8.0 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain WD40_like PF17005.5 EPS33376.1 - 0.0071 15.7 0.0 1.1 8.5 0.0 2.8 2 1 0 3 3 3 1 WD40-like domain PD40 PF07676.12 EPS33376.1 - 0.017 15.1 0.4 20 5.3 0.0 4.3 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat TPR_12 PF13424.6 EPS33377.1 - 8.8e-05 22.7 14.5 0.069 13.5 0.2 4.9 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EPS33377.1 - 0.0043 16.8 6.6 4.7 7.2 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EPS33377.1 - 0.018 14.4 7.2 0.31 10.3 0.3 4.2 4 1 0 4 4 4 0 MalT-like TPR region TPR_7 PF13176.6 EPS33377.1 - 0.044 13.8 4.6 5.4 7.3 0.4 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EPS33377.1 - 0.067 13.3 15.4 1.3 9.4 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 EPS33377.1 - 0.13 12.2 6.8 0.24 11.3 0.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat VEK-30 PF12107.8 EPS33377.1 - 0.16 12.0 0.3 6.9 6.7 0.4 2.6 2 0 0 2 2 2 0 Plasminogen (Pg) ligand in fibrinolytic pathway TPR_8 PF13181.6 EPS33377.1 - 0.25 11.6 0.1 0.25 11.6 0.1 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 EPS33377.1 - 0.58 9.9 5.3 8.8 6.1 0.2 3.7 3 0 0 3 3 3 0 TPR repeat SRAP PF02586.14 EPS33378.1 - 7.4e-81 270.9 0.0 1e-80 270.4 0.0 1.2 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) Med1 PF10744.9 EPS33380.1 - 4.5e-127 424.6 0.0 5.7e-127 424.2 0.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Cir_N PF10197.9 EPS33380.1 - 0.54 10.5 2.5 0.4 10.9 0.2 2.0 2 0 0 2 2 2 0 N-terminal domain of CBF1 interacting co-repressor CIR Gln-synt_C PF00120.24 EPS33384.1 - 5.9e-15 55.1 0.0 1.6e-13 50.4 0.0 2.1 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 EPS33384.1 - 1.9e-14 53.2 0.0 3.5e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain MFS_1 PF07690.16 EPS33385.1 - 3.1e-37 128.3 44.4 1.3e-31 109.9 27.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily FPN1 PF06963.12 EPS33385.1 - 0.019 13.5 1.9 0.058 11.9 1.9 1.7 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Imm57 PF15596.6 EPS33385.1 - 0.03 14.6 0.0 0.057 13.7 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 57 UNC-93 PF05978.16 EPS33385.1 - 0.075 12.7 5.5 0.079 12.7 3.0 2.1 1 1 1 2 2 2 0 Ion channel regulatory protein UNC-93 zf-CCHC PF00098.23 EPS33386.1 - 1.5e-14 53.3 42.1 0.00018 21.4 2.2 6.3 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_4 PF14392.6 EPS33386.1 - 6.5e-06 25.8 23.1 0.083 12.6 0.2 5.3 4 1 1 5 5 5 4 Zinc knuckle zf-CCHC_3 PF13917.6 EPS33386.1 - 0.018 15.0 1.1 0.018 15.0 1.1 4.3 3 1 1 4 4 4 0 Zinc knuckle CitX PF03802.14 EPS33386.1 - 0.077 12.8 3.7 2 8.1 0.2 2.7 1 1 1 2 2 2 0 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase DZR PF12773.7 EPS33386.1 - 7.4 6.7 28.1 3.5 7.7 5.5 3.4 2 1 0 2 2 2 0 Double zinc ribbon DUF846 PF05832.12 EPS33387.1 - 2.8e-45 153.8 7.7 3.3e-45 153.5 7.7 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF1771 PF08590.10 EPS33388.1 - 7.3e-15 55.1 12.1 8.5e-15 54.9 10.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 EPS33388.1 - 2.2e-09 37.6 0.1 1.7e-08 34.7 0.0 2.4 2 0 0 2 2 2 1 Smr domain zf_CCCH_4 PF18345.1 EPS33388.1 - 9.8e-08 31.8 9.4 2.1e-05 24.4 1.2 2.9 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 EPS33388.1 - 5.6e-06 26.1 2.7 0.0045 16.9 0.1 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 EPS33388.1 - 0.00017 21.8 2.4 0.18 12.0 0.0 2.4 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 EPS33388.1 - 0.00026 20.7 12.4 0.0046 16.7 1.5 3.1 2 1 0 2 2 2 2 CCCH-type zinc finger zf-CCCH_2 PF14608.6 EPS33388.1 - 0.00033 21.0 6.1 0.18 12.3 1.0 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger CUE PF02845.16 EPS33388.1 - 0.034 13.9 2.2 0.048 13.4 0.2 2.3 2 0 0 2 2 2 0 CUE domain Torus PF16131.5 EPS33388.1 - 0.12 13.1 2.2 2.8 8.7 0.4 2.5 1 1 1 2 2 2 0 Torus domain SNARE_assoc PF09335.11 EPS33389.1 - 8.2e-14 52.1 6.9 5.4e-13 49.5 5.5 2.4 2 1 0 2 2 2 1 SNARE associated Golgi protein DUF1664 PF07889.12 EPS33389.1 - 0.15 12.1 1.3 0.32 11.0 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Amino_oxidase PF01593.24 EPS33390.1 - 1.7e-86 291.3 0.1 4e-85 286.8 0.1 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.17 EPS33390.1 - 1.7e-15 57.1 0.0 3.5e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.6 EPS33390.1 - 9.6e-08 32.2 0.0 2.5e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.19 EPS33390.1 - 9.1e-05 22.8 4.1 0.00022 21.6 0.5 2.7 1 1 1 2 2 2 1 HMG (high mobility group) box DAO PF01266.24 EPS33390.1 - 0.0065 16.1 0.0 0.016 14.8 0.0 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase HMG_box_2 PF09011.10 EPS33390.1 - 0.019 15.6 0.3 0.044 14.4 0.3 1.6 1 0 0 1 1 1 0 HMG-box domain Pyr_redox_2 PF07992.14 EPS33390.1 - 0.025 13.8 0.3 0.2 10.8 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EPS33390.1 - 0.083 12.9 0.7 0.49 10.4 0.1 2.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EPS33392.1 - 7.2e-49 166.6 0.1 8.5e-49 166.4 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EPS33392.1 - 1.1e-18 67.5 0.0 1.9e-17 63.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPS33392.1 - 2.2e-15 57.0 0.2 1.9e-13 50.7 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPS33392.1 - 3.1e-05 24.1 1.0 0.059 13.6 0.1 2.9 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 EPS33392.1 - 0.00015 22.2 0.0 0.011 16.1 0.0 2.7 2 1 0 2 2 2 1 Putative NAD(P)-binding K_oxygenase PF13434.6 EPS33392.1 - 0.00098 18.3 0.2 0.33 10.1 0.0 3.0 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EPS33392.1 - 0.0011 18.3 0.1 0.0042 16.3 0.1 2.0 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 EPS33392.1 - 0.0031 16.8 1.1 2.4 7.3 0.1 3.0 2 1 1 3 3 3 2 FAD binding domain FAD_oxidored PF12831.7 EPS33392.1 - 0.011 15.1 0.2 0.28 10.5 0.1 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 EPS33392.1 - 0.094 11.8 4.6 12 4.8 0.1 4.0 3 2 2 5 5 5 0 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EPS33392.1 - 0.14 11.2 3.2 1.2 8.1 0.2 3.2 3 1 2 5 5 5 0 FAD binding domain PBP1_TM PF14812.6 EPS33393.1 - 3.7 8.0 13.1 0.65 10.4 4.3 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Peptidase_S8 PF00082.22 EPS33395.1 - 2.7e-36 125.3 0.6 4.4e-36 124.7 0.6 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 EPS33395.1 - 3.2e-27 94.4 0.3 6e-27 93.5 0.3 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain PX PF00787.24 EPS33396.1 - 3.1e-19 69.0 0.2 6.4e-19 68.0 0.2 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.10 EPS33396.1 - 2.6e-15 56.6 5.9 6.6e-09 35.7 0.4 2.1 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.18 EPS33396.1 - 6.8e-05 22.6 4.6 0.0038 16.9 4.7 2.4 1 1 0 1 1 1 1 BAR domain Sec34 PF04136.15 EPS33396.1 - 0.0027 17.6 0.1 0.0066 16.3 0.1 1.6 1 0 0 1 1 1 1 Sec34-like family FlaC_arch PF05377.11 EPS33396.1 - 0.086 13.2 0.8 18 5.8 0.0 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Occludin_ELL PF07303.13 EPS33396.1 - 0.98 10.2 4.7 1.8 9.3 0.0 3.0 3 0 0 3 3 3 0 Occludin homology domain FAD_binding_3 PF01494.19 EPS33397.1 - 5e-20 72.0 0.0 1.6e-16 60.5 0.0 3.0 2 1 0 2 2 2 2 FAD binding domain SE PF08491.10 EPS33397.1 - 1.2e-06 27.8 0.0 2e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.12 EPS33397.1 - 0.0024 17.0 0.0 0.0076 15.3 0.0 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EPS33397.1 - 0.0077 15.5 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EPS33397.1 - 0.0088 16.0 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 EPS33397.1 - 0.045 12.9 0.0 0.085 12.0 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EPS33397.1 - 0.054 13.1 0.0 0.67 9.5 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EPS33397.1 - 0.073 11.9 0.0 0.69 8.7 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.14 EPS33397.1 - 0.11 11.1 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 EPS33397.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.6 EPS33397.1 - 0.12 12.6 0.0 0.32 11.3 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain tRNA-synt_His PF13393.6 EPS33398.1 - 9.6e-36 123.6 0.0 1.1e-29 103.7 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 EPS33398.1 - 1.8e-14 53.7 0.0 3.7e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 EPS33398.1 - 2.3e-07 30.6 0.0 9.1e-07 28.6 0.0 1.8 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs tRNA-synt_2b PF00587.25 EPS33398.1 - 0.00012 22.1 0.0 0.00022 21.3 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) UCH PF00443.29 EPS33400.1 - 8e-57 192.7 0.1 1.6e-56 191.7 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EPS33400.1 - 1.8e-28 100.1 0.6 2.2e-27 96.5 0.6 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EPS33400.1 - 0.0037 16.8 5.2 0.068 12.6 2.5 3.1 3 0 0 3 3 3 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase Yos1 PF08571.10 EPS33402.1 - 7e-37 125.6 1.1 7.9e-37 125.4 1.1 1.0 1 0 0 1 1 1 1 Yos1-like Glyco_transf_22 PF03901.17 EPS33403.1 - 7.1e-44 150.7 11.6 8.6e-44 150.4 11.6 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Complex1_49kDa PF00346.19 EPS33404.1 - 3.7e-124 413.2 0.0 5.1e-124 412.8 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.19 EPS33404.1 - 0.0097 14.8 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 Nickel-dependent hydrogenase RNA_pol_A_bac PF01000.26 EPS33405.1 - 1.3e-24 86.7 0.0 2.5e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EPS33405.1 - 1.4e-18 66.1 0.0 2.1e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain ThiF PF00899.21 EPS33406.1 - 4.7e-67 225.9 0.0 6.5e-67 225.4 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 EPS33406.1 - 1e-28 99.3 0.0 1.7e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 E2 binding domain Shikimate_DH PF01488.20 EPS33406.1 - 0.00026 21.0 0.3 0.001 19.2 0.0 2.0 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.14 EPS33406.1 - 0.067 12.8 1.1 0.18 11.4 0.0 2.0 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Ecm33 PF12454.8 EPS33406.1 - 0.071 13.3 0.3 0.15 12.2 0.3 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Sacchrp_dh_NADP PF03435.18 EPS33406.1 - 0.071 13.4 0.1 0.82 9.9 0.1 2.7 4 0 0 4 4 4 0 Saccharopine dehydrogenase NADP binding domain Pyr_redox PF00070.27 EPS33406.1 - 0.091 13.3 0.0 0.2 12.2 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UBA_e1_thiolCys PF10585.9 EPS33406.1 - 0.11 12.4 3.6 1.5 8.7 0.1 2.2 1 1 1 2 2 2 0 Ubiquitin-activating enzyme active site PglD_N PF17836.1 EPS33406.1 - 0.23 12.1 1.5 0.58 10.8 0.7 2.1 1 1 0 2 2 2 0 PglD N-terminal domain Telomere_reg-2 PF10193.9 EPS33407.1 - 1.5e-30 105.8 0.0 4.3e-30 104.4 0.0 1.9 1 0 0 1 1 1 1 Telomere length regulation protein Sec1 PF00995.23 EPS33408.1 - 5.5e-118 395.7 0.0 6.3e-118 395.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Tup_N PF08581.10 EPS33408.1 - 0.079 13.3 0.9 0.63 10.4 0.4 2.5 2 0 0 2 2 2 0 Tup N-terminal Transposase_22 PF02994.14 EPS33408.1 - 0.1 12.8 0.2 0.6 10.3 0.0 2.4 2 0 0 2 2 2 0 L1 transposable element RBD-like domain DpaA_N PF16924.5 EPS33408.1 - 0.14 12.3 0.0 0.48 10.5 0.0 1.9 1 1 0 1 1 1 0 Dipicolinate synthase subunit A N-terminal domain Spem1 PF15670.5 EPS33409.1 - 0.086 12.4 0.9 0.15 11.6 0.9 1.3 1 0 0 1 1 1 0 Spermatid maturation protein 1 ESM4 PF15952.5 EPS33409.1 - 7.8 6.9 7.5 0.53 10.7 0.7 2.1 1 1 0 2 2 2 0 Enhancer of split M4 family zf-H2C2_2 PF13465.6 EPS33410.1 - 5.1e-10 39.3 15.3 3.7e-05 24.0 0.4 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 EPS33410.1 - 1.1e-09 38.2 11.6 2.2e-05 24.7 4.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPS33410.1 - 1e-06 29.1 10.9 0.0013 19.4 3.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 EPS33410.1 - 6.4e-06 26.4 1.3 1.8e-05 25.0 1.3 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 EPS33410.1 - 6.8e-05 22.8 9.0 0.00012 22.0 2.4 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EPS33410.1 - 0.00073 19.8 1.8 0.00073 19.8 1.8 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EPS33410.1 - 0.069 13.5 1.1 0.069 13.5 1.1 1.6 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 EPS33410.1 - 0.1 12.5 4.2 2.8 7.9 0.4 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Actin_micro PF17003.5 EPS33410.1 - 0.22 10.7 0.2 0.3 10.2 0.2 1.1 1 0 0 1 1 1 0 Putative actin-like family zf-C2H2_11 PF16622.5 EPS33410.1 - 0.23 11.3 6.4 4.9 7.0 0.5 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type Nepo_coat PF03391.15 EPS33411.1 - 0.11 12.0 0.1 0.14 11.6 0.1 1.2 1 0 0 1 1 1 0 Nepovirus coat protein, central domain SF3b1 PF08920.10 EPS33416.1 - 5.6e-28 97.8 0.9 5.6e-28 97.8 0.9 2.3 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT_EZ PF13513.6 EPS33416.1 - 1.6e-11 44.5 0.9 0.015 15.8 0.0 7.3 7 0 0 7 7 7 2 HEAT-like repeat HEAT_2 PF13646.6 EPS33416.1 - 3.6e-11 43.3 7.2 0.21 12.0 0.1 8.5 7 1 3 10 10 10 3 HEAT repeats HEAT PF02985.22 EPS33416.1 - 5.2e-10 38.7 10.0 0.074 13.3 0.4 8.8 9 0 0 9 9 9 3 HEAT repeat Adaptin_N PF01602.20 EPS33416.1 - 7.4e-07 28.1 0.7 0.0014 17.3 0.0 3.3 2 2 1 3 3 3 2 Adaptin N terminal region Cnd1 PF12717.7 EPS33416.1 - 2.6e-05 24.3 5.5 0.49 10.4 0.1 6.5 4 2 3 7 7 7 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EPS33416.1 - 7.2e-05 23.3 0.8 2.5 8.8 0.0 5.3 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region UNC45-central PF11701.8 EPS33416.1 - 0.00013 22.0 0.1 0.00043 20.3 0.0 1.9 2 0 0 2 2 2 1 Myosin-binding striated muscle assembly central NUC173 PF08161.12 EPS33416.1 - 0.00049 19.8 0.2 1.2 8.8 0.0 4.2 4 1 0 5 5 5 1 NUC173 domain CLASP_N PF12348.8 EPS33416.1 - 0.0035 16.9 0.2 0.93 9.0 0.0 3.3 3 0 0 3 3 3 1 CLASP N terminal DUF3385 PF11865.8 EPS33416.1 - 0.004 17.1 4.3 1 9.2 0.1 5.3 3 2 1 4 4 4 1 Domain of unknown function (DUF3385) MMS19_C PF12460.8 EPS33416.1 - 0.017 14.2 0.0 0.93 8.5 0.0 3.1 3 1 0 3 3 3 0 RNAPII transcription regulator C-terminal RTP1_C1 PF10363.9 EPS33416.1 - 0.07 13.3 1.4 10 6.3 0.1 3.9 4 0 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 B56 PF01603.20 EPS33416.1 - 0.1 11.5 0.0 0.52 9.2 0.0 2.1 1 1 1 2 2 2 0 Protein phosphatase 2A regulatory B subunit (B56 family) APH PF01636.23 EPS33417.1 - 6.6e-09 36.0 0.0 1e-08 35.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EPS33417.1 - 0.027 13.8 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase DUF3455 PF11937.8 EPS33420.1 - 4.4e-41 140.9 0.0 5.3e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) SAP PF02037.27 EPS33421.1 - 1e-11 44.3 0.1 2.5e-11 43.0 0.1 1.7 1 0 0 1 1 1 1 SAP domain Tho1_MOS11_C PF18592.1 EPS33421.1 - 5.3e-09 35.8 0.7 5.3e-09 35.8 0.7 1.9 2 0 0 2 2 2 1 Tho1/MOS11 C-terminal domain Transthyretin PF00576.21 EPS33421.1 - 0.14 12.9 0.1 0.41 11.3 0.1 2.0 1 1 0 1 1 1 0 HIUase/Transthyretin family Methyltransf_11 PF08241.12 EPS33422.1 - 0.00098 19.7 0.0 0.0021 18.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Annexin PF00191.20 EPS33423.1 - 1.1e-58 195.2 0.8 2.9e-19 68.9 0.0 4.1 4 0 0 4 4 4 4 Annexin SH3_1 PF00018.28 EPS33424.1 - 8.6e-05 22.1 0.7 0.00021 20.8 0.7 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EPS33424.1 - 0.00025 20.9 0.5 0.00025 20.9 0.5 2.3 2 0 0 2 2 2 1 Variant SH3 domain ZZ PF00569.17 EPS33424.1 - 0.00062 19.5 6.6 0.00062 19.5 6.6 3.8 4 0 0 4 4 4 2 Zinc finger, ZZ type SH3_2 PF07653.17 EPS33424.1 - 0.014 15.1 0.1 0.044 13.5 0.1 1.9 1 0 0 1 1 1 0 Variant SH3 domain GP24_25 PF17388.2 EPS33424.1 - 0.085 12.8 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Tail assembly gene products 24 & 25 RRN3 PF05327.11 EPS33424.1 - 0.57 8.7 2.6 0.28 9.7 0.1 1.6 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 CBM_21 PF03370.13 EPS33429.1 - 1.8e-34 118.3 2.6 3e-34 117.6 2.6 1.3 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 EPS33429.1 - 9e-11 42.2 2.7 1.7e-10 41.3 2.7 1.5 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) PAT1 PF09770.9 EPS33429.1 - 5.5 5.1 10.4 8.3 4.5 10.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CENP-T_C PF15511.6 EPS33430.1 - 4.4e-09 36.4 0.1 5.3e-09 36.2 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 EPS33430.1 - 1.9e-05 25.1 0.2 2.2e-05 24.8 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 EPS33430.1 - 5e-05 23.4 0.2 7.3e-05 22.9 0.2 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EPS33430.1 - 0.00012 22.3 0.1 0.00021 21.5 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 EPS33430.1 - 0.00017 21.9 0.1 0.00023 21.5 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 EPS33430.1 - 0.0038 17.3 0.0 0.0045 17.0 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EPS33430.1 - 0.0045 17.0 0.0 0.0054 16.7 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated UPF0137 PF03677.13 EPS33430.1 - 0.05 13.4 0.2 0.061 13.1 0.2 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0137) TFIID_20kDa PF03847.13 EPS33430.1 - 0.059 13.9 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A HIGH_NTase1_ass PF16581.5 EPS33430.1 - 0.073 13.1 0.0 0.082 12.9 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Mito_carr PF00153.27 EPS33431.1 - 2.8e-49 165.0 1.1 1e-15 57.4 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF883 PF05957.13 EPS33431.1 - 0.23 12.1 2.7 0.57 10.8 2.0 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) EBP PF05241.12 EPS33432.1 - 1.1e-68 230.2 7.3 1.3e-68 230.0 7.3 1.0 1 0 0 1 1 1 1 Emopamil binding protein L31 PF09784.9 EPS33438.1 - 3.5e-46 155.8 1.9 3.9e-46 155.7 1.9 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Acyltransferase PF01553.21 EPS33439.1 - 4.7e-18 65.1 0.0 9.2e-18 64.2 0.0 1.5 1 1 0 1 1 1 1 Acyltransferase LRR_1 PF00560.33 EPS33440.1 - 0.13 12.9 0.1 29 5.8 0.0 3.3 3 0 0 3 3 3 0 Leucine Rich Repeat DEAD PF00270.29 EPS33441.1 - 3.3e-40 137.7 1.0 4.9e-40 137.2 1.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPS33441.1 - 1.6e-31 109.0 0.1 5.2e-30 104.0 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPS33441.1 - 0.00011 22.3 0.0 0.00024 21.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit RraA-like PF03737.15 EPS33442.1 - 1.6e-24 86.8 0.2 2.8e-24 86.0 0.2 1.4 1 1 0 1 1 1 1 Aldolase/RraA Thiolase_N PF00108.23 EPS33443.1 - 1.7e-74 250.5 2.9 1.7e-74 250.5 2.9 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EPS33443.1 - 4.5e-43 145.8 0.3 1e-42 144.7 0.3 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EPS33443.1 - 0.0077 15.8 2.0 0.05 13.2 0.5 2.6 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EPS33443.1 - 0.058 13.2 0.3 18 5.3 0.1 2.7 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Drf_GBD PF06371.13 EPS33445.1 - 2.2e-15 56.7 0.1 8.7e-09 35.2 0.0 2.4 2 0 0 2 2 2 2 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 EPS33445.1 - 0.055 13.1 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 Diaphanous FH3 Domain Xpo1 PF08389.12 EPS33445.1 - 0.15 12.1 0.0 2.9 7.9 0.0 2.4 2 0 0 2 2 2 0 Exportin 1-like protein Nramp PF01566.18 EPS33446.1 - 5.6e-93 311.8 20.8 1.2e-92 310.6 20.8 1.5 1 1 0 1 1 1 1 Natural resistance-associated macrophage protein Snf7 PF03357.21 EPS33447.1 - 1.6e-42 145.1 14.6 1.9e-42 144.8 14.6 1.0 1 0 0 1 1 1 1 Snf7 Zwint PF15556.6 EPS33447.1 - 0.00019 21.0 6.8 0.00024 20.7 6.8 1.2 1 0 0 1 1 1 1 ZW10 interactor DUF4201 PF13870.6 EPS33447.1 - 0.00045 20.0 6.5 0.00045 20.0 6.5 1.8 1 1 1 2 2 2 2 Domain of unknown function (DUF4201) DUF3584 PF12128.8 EPS33447.1 - 0.0044 14.6 6.3 0.0057 14.2 6.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) NPV_P10 PF05531.12 EPS33447.1 - 0.0083 16.6 6.7 0.17 12.4 0.8 2.8 3 0 0 3 3 3 2 Nucleopolyhedrovirus P10 protein Lebercilin PF15619.6 EPS33447.1 - 0.037 13.7 6.6 0.058 13.1 6.6 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease AF0941-like PF14591.6 EPS33447.1 - 0.046 14.3 3.9 0.076 13.6 3.9 1.3 1 0 0 1 1 1 0 AF0941-like DUF848 PF05852.11 EPS33447.1 - 0.052 13.7 6.5 0.074 13.2 5.0 2.0 2 1 1 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) FlaC_arch PF05377.11 EPS33447.1 - 0.49 10.8 7.4 15 6.1 0.0 3.3 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) SAPS PF04499.15 EPS33448.1 - 6.7e-202 671.6 3.0 2.1e-200 666.7 0.0 2.9 3 0 0 3 3 3 1 SIT4 phosphatase-associated protein SET PF00856.28 EPS33449.1 - 9.8e-06 26.0 0.0 2.7e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 SET domain Complex1_51K PF01512.17 EPS33450.1 - 8.2e-48 162.1 0.0 1.4e-47 161.4 0.0 1.4 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 EPS33450.1 - 3.6e-29 100.7 0.3 6.5e-29 99.8 0.3 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 EPS33450.1 - 2e-09 37.1 0.0 8e-09 35.2 0.0 2.1 2 0 0 2 2 2 1 SLBB domain DUF3568 PF12092.8 EPS33450.1 - 0.15 12.2 0.7 0.29 11.2 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) Nup96 PF12110.8 EPS33451.1 - 1.3e-81 273.9 1.2 2.5e-81 273.0 0.6 1.7 2 0 0 2 2 2 1 Nuclear protein 96 Nucleoporin2 PF04096.14 EPS33451.1 - 7e-53 178.8 0.0 1.1e-52 178.1 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.6 EPS33451.1 - 1.3e-14 54.8 179.9 1.2e-06 29.3 35.5 10.1 4 1 8 12 12 12 5 Nucleoporin FG repeat region SLT_L PF14718.6 EPS33451.1 - 0.36 11.0 1.4 1 9.5 1.4 1.7 1 0 0 1 1 1 0 Soluble lytic murein transglycosylase L domain AMP-binding PF00501.28 EPS33452.1 - 1.4e-88 297.4 0.1 1.7e-88 297.1 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EPS33452.1 - 3.8e-27 95.1 0.4 2.1e-25 89.5 0.5 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EPS33452.1 - 8.6e-17 60.8 0.6 2.2e-16 59.5 0.6 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus PALP PF00291.25 EPS33453.1 - 9.1e-66 222.2 0.2 1e-65 222.1 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NAD_binding_7 PF13241.6 EPS33453.1 - 0.029 14.8 0.0 0.06 13.8 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding DAP_B PF07930.12 EPS33454.1 - 3.2e-70 235.8 0.0 4.6e-70 235.3 0.0 1.2 1 0 0 1 1 1 1 D-aminopeptidase, domain B Beta-lactamase PF00144.24 EPS33454.1 - 2.5e-37 128.9 0.0 3.5e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.8 EPS33454.1 - 0.06 13.8 0.0 0.22 12.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3471) GET2 PF08690.10 EPS33455.1 - 1.7e-14 54.2 5.5 4.2e-13 49.7 5.5 2.4 1 1 0 1 1 1 1 GET complex subunit GET2 PepSY_TM PF03929.16 EPS33455.1 - 4 7.0 6.3 0.52 9.9 0.2 2.2 2 1 0 2 2 2 0 PepSY-associated TM region DUF1631 PF07793.11 EPS33455.1 - 9.6 4.5 8.1 11 4.3 8.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) GFA PF04828.14 EPS33456.1 - 3.3e-14 53.0 1.2 1.5e-13 50.8 1.2 1.9 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Arrestin_C PF02752.22 EPS33457.1 - 5.6e-09 36.5 0.0 2.1e-06 28.2 0.0 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EPS33457.1 - 2.6e-05 24.3 0.0 0.00013 22.1 0.0 1.9 1 1 1 2 2 2 1 Arrestin (or S-antigen), N-terminal domain C2 PF00168.30 EPS33458.1 - 9e-30 103.0 0.0 1.2e-15 57.7 0.0 2.5 2 0 0 2 2 2 2 C2 domain CW_7 PF08230.11 EPS33459.1 - 0.023 14.4 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 CW_7 repeat FMN_red PF03358.15 EPS33460.1 - 1.9e-25 89.4 0.0 2.8e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase DnaJ PF00226.31 EPS33460.1 - 0.074 13.2 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 DnaJ domain Nop53 PF07767.11 EPS33461.1 - 0.057 12.8 6.7 0.092 12.1 6.7 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Macoilin PF09726.9 EPS33461.1 - 0.42 9.1 4.5 0.57 8.7 4.5 1.1 1 0 0 1 1 1 0 Macoilin family Paf1 PF03985.13 EPS33461.1 - 0.45 9.5 7.6 0.68 8.9 7.6 1.1 1 0 0 1 1 1 0 Paf1 SRP-alpha_N PF04086.13 EPS33461.1 - 0.46 10.4 8.8 0.7 9.8 8.8 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Apt1 PF10351.9 EPS33461.1 - 1.7 7.4 6.4 2.6 6.8 6.4 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC45 PF02724.14 EPS33461.1 - 2.7 6.2 9.6 3.8 5.7 9.6 1.1 1 0 0 1 1 1 0 CDC45-like protein IMS PF00817.20 EPS33463.1 - 1.3e-35 122.6 0.0 2.5e-35 121.7 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 EPS33463.1 - 2.3e-19 70.2 0.3 8e-19 68.5 0.2 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 EPS33463.1 - 0.0004 20.5 0.0 0.0022 18.2 0.0 2.3 2 0 0 2 2 2 1 IMS family HHH motif zf_UBZ PF18439.1 EPS33463.1 - 0.053 13.1 0.1 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger Tankyrase_bdg_C PF15327.6 EPS33463.1 - 0.094 13.2 0.6 2.2 8.7 0.0 2.8 3 0 0 3 3 3 0 Tankyrase binding protein C terminal domain HHH_5 PF14520.6 EPS33463.1 - 0.1 13.2 0.0 0.26 11.9 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix domain Reprolysin_5 PF13688.6 EPS33464.1 - 1.3e-56 191.9 7.8 1.3e-56 191.9 7.8 2.0 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 EPS33464.1 - 2.1e-46 158.2 2.3 3.5e-46 157.4 2.3 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 EPS33464.1 - 7.8e-44 149.9 2.1 7.8e-44 149.9 2.1 1.9 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.23 EPS33464.1 - 2.4e-17 63.5 32.0 2.4e-17 63.5 32.0 4.7 4 1 0 4 4 4 1 Disintegrin Reprolysin_3 PF13582.6 EPS33464.1 - 9.5e-11 42.3 0.0 2.5e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.19 EPS33464.1 - 5.1e-05 23.5 0.0 0.00011 22.5 0.0 1.5 1 0 0 1 1 1 1 Reprolysin family propeptide ADAM_CR_2 PF17771.1 EPS33464.1 - 0.014 15.9 6.4 0.014 15.9 6.4 4.9 1 1 2 3 3 3 0 ADAM cysteine-rich domain Peptidase_M66 PF10462.9 EPS33464.1 - 0.017 14.1 0.0 0.034 13.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase M66 Mid2 PF04478.12 EPS33464.1 - 0.079 12.8 0.4 0.22 11.3 0.4 1.7 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor EF-hand_1 PF00036.32 EPS33465.1 - 1.6e-15 55.4 3.2 1.8e-05 24.0 0.1 4.0 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 EPS33465.1 - 2.5e-15 56.7 3.1 6.6e-09 36.1 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EPS33465.1 - 1.3e-13 49.6 5.4 1.7e-05 24.3 0.2 4.0 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 EPS33465.1 - 2e-10 40.3 3.1 5.9e-08 32.4 0.2 2.7 2 1 1 3 3 3 2 EF-hand domain pair TFIIA PF03153.13 EPS33465.1 - 0.0023 18.0 5.5 0.0029 17.7 5.5 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit EF-hand_4 PF12763.7 EPS33465.1 - 0.015 15.3 0.1 0.051 13.5 0.0 2.0 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand DUF3572 PF12096.8 EPS33465.1 - 0.029 14.6 0.1 1.1 9.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3572) PhetRS_B1 PF18262.1 EPS33465.1 - 0.048 13.9 0.1 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain ANAPC_CDC26 PF10471.9 EPS33465.1 - 0.23 12.3 12.4 0.13 13.1 5.7 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 EF-hand_5 PF13202.6 EPS33465.1 - 0.78 9.3 10.5 1 9.0 0.4 3.3 4 0 0 4 4 4 0 EF hand SUIM_assoc PF16619.5 EPS33465.1 - 1.9 8.6 14.9 0.16 12.1 9.5 2.2 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Zn_clus PF00172.18 EPS33466.1 - 0.0014 18.7 13.6 0.0022 18.1 13.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MgsA_C PF12002.8 EPS33467.1 - 7.5e-57 191.9 0.0 1.2e-56 191.2 0.0 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 EPS33467.1 - 2.8e-23 82.0 1.1 6e-23 81.0 0.4 1.9 2 0 0 2 2 2 1 AAA C-terminal domain AAA PF00004.29 EPS33467.1 - 9.7e-14 51.9 0.0 2.4e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EPS33467.1 - 4.4e-09 36.3 0.0 9.1e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 EPS33467.1 - 4.3e-05 23.0 0.0 0.15 11.5 0.0 2.2 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EPS33467.1 - 8.4e-05 22.3 0.0 0.0022 17.7 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 EPS33467.1 - 0.0001 22.3 0.0 0.00095 19.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EPS33467.1 - 0.00039 20.8 0.2 0.081 13.3 0.1 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_3 PF07726.11 EPS33467.1 - 0.00091 19.1 0.0 0.0034 17.3 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EPS33467.1 - 0.00095 19.4 0.1 0.0029 17.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 EPS33467.1 - 0.0038 16.4 0.0 0.0063 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 EPS33467.1 - 0.018 15.0 0.0 0.038 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 EPS33467.1 - 0.02 14.9 0.1 2.8 7.9 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EPS33467.1 - 0.03 14.0 0.3 0.068 12.9 0.3 1.6 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.13 EPS33467.1 - 0.042 13.0 0.0 0.075 12.2 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain TsaE PF02367.17 EPS33467.1 - 0.09 12.8 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 EPS33467.1 - 0.096 12.4 0.0 6 6.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.6 EPS33467.1 - 0.099 12.8 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain SKI PF01202.22 EPS33467.1 - 0.11 12.6 0.1 0.25 11.4 0.1 1.6 1 0 0 1 1 1 0 Shikimate kinase PIF1 PF05970.14 EPS33467.1 - 0.13 11.4 0.1 0.2 10.8 0.1 1.2 1 0 0 1 1 1 0 PIF1-like helicase DUF927 PF06048.11 EPS33467.1 - 0.13 11.8 0.1 0.21 11.1 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF927) NB-ARC PF00931.22 EPS33467.1 - 0.18 11.0 0.1 0.29 10.3 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.6 EPS33467.1 - 0.19 11.5 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain zf_C2H2_13 PF18508.1 EPS33467.1 - 0.29 10.8 0.8 0.57 9.8 0.8 1.5 1 0 0 1 1 1 0 Zinc finger domain Aminotran_1_2 PF00155.21 EPS33468.1 - 4.7e-73 246.4 0.0 5.5e-73 246.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EPS33468.1 - 0.0073 14.9 0.0 0.012 14.1 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 EPS33468.1 - 0.011 15.0 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_5 PF00266.19 EPS33468.1 - 0.022 13.7 0.0 0.066 12.2 0.0 1.7 1 1 0 1 1 1 0 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EPS33468.1 - 0.025 13.9 0.0 0.089 12.1 0.0 1.9 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family zf-Mss51 PF13824.6 EPS33469.1 - 0.016 15.3 7.6 0.59 10.3 7.6 2.7 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.18 EPS33469.1 - 0.056 13.5 6.6 0.13 12.3 5.7 2.2 1 1 1 2 2 2 0 MYND finger DUF948 PF06103.11 EPS33471.1 - 0.026 14.8 1.6 0.026 14.8 1.6 4.3 5 1 0 5 5 5 0 Bacterial protein of unknown function (DUF948) Ald_Xan_dh_C2 PF02738.18 EPS33472.1 - 1.8e-203 677.0 1.1 2.7e-203 676.4 1.1 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 EPS33472.1 - 4.2e-48 163.3 0.0 8.4e-48 162.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 EPS33472.1 - 1.3e-33 115.2 0.3 5e-33 113.4 0.1 2.2 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.22 EPS33472.1 - 1.4e-33 115.5 0.0 3e-33 114.5 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 EPS33472.1 - 2.7e-28 97.8 0.0 6e-28 96.7 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 EPS33472.1 - 4.5e-08 32.9 2.3 5.5e-08 32.6 0.2 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DUF218 PF02698.17 EPS33472.1 - 0.045 13.8 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 DUF218 domain HTH_Tnp_ISL3 PF13542.6 EPS33473.1 - 0.074 12.5 0.1 0.15 11.5 0.1 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 NAD_binding_4 PF07993.12 EPS33475.1 - 6.7e-68 228.6 0.0 1e-67 228.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 EPS33475.1 - 1.7e-65 221.3 0.0 2.3e-65 220.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.20 EPS33475.1 - 1.5e-12 46.9 0.3 9.5e-12 44.3 0.3 2.1 1 1 0 1 1 1 1 Condensation domain Epimerase PF01370.21 EPS33475.1 - 4.1e-09 36.2 0.0 2.5e-08 33.7 0.0 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EPS33475.1 - 2.6e-07 30.9 0.0 6.2e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.19 EPS33475.1 - 0.00011 21.3 0.0 0.00053 19.1 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 EPS33475.1 - 0.00033 21.6 0.0 0.0013 19.7 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.6 EPS33475.1 - 0.00067 19.6 0.0 0.069 13.0 0.0 2.6 2 0 0 2 2 2 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 EPS33475.1 - 0.013 14.6 0.0 0.27 10.3 0.0 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain Arylsulfotran_2 PF14269.6 EPS33477.1 - 1.4e-44 152.6 0.3 2.1e-44 152.1 0.3 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.11 EPS33477.1 - 7.6e-09 34.9 0.8 1.9e-07 30.3 0.8 2.5 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) DUF4229 PF14012.6 EPS33477.1 - 0.02 15.0 0.7 0.037 14.1 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) Beta_elim_lyase PF01212.21 EPS33478.1 - 3e-34 118.6 0.0 3.7e-34 118.4 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 EPS33478.1 - 1.5e-07 31.0 0.0 2.1e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EPS33478.1 - 1.2e-05 24.5 0.0 1.5e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Pyridoxal_deC PF00282.19 EPS33478.1 - 0.0036 16.1 0.0 0.0059 15.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Fungal_trans PF04082.18 EPS33479.1 - 1.9e-13 50.1 0.8 1.9e-13 50.1 0.8 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS33479.1 - 4e-06 26.9 8.8 7.7e-06 25.9 8.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF5510 PF17629.2 EPS33480.1 - 0.086 12.8 7.0 1.8 8.6 5.2 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5510) UPRTase PF14681.6 EPS33480.1 - 0.087 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Oxidored_FMN PF00724.20 EPS33481.1 - 2e-78 264.0 0.0 3e-78 263.5 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1848 PF08902.11 EPS33481.1 - 0.019 14.7 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) Ham1p_like PF01725.16 EPS33482.1 - 1.6e-50 171.6 0.0 1.8e-50 171.5 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Aldo_ket_red PF00248.21 EPS33483.1 - 5.6e-70 235.8 0.0 6.3e-70 235.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Mannosyl_trans2 PF04188.13 EPS33485.1 - 4.7e-51 174.5 15.6 7e-51 173.9 15.6 1.2 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V) BLM10_mid PF16507.5 EPS33486.1 - 9.4e-206 684.5 0.0 4.2e-205 682.4 0.0 1.9 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 EPS33486.1 - 3.9e-29 100.4 0.0 1.6e-28 98.4 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) BLM10_N PF16547.5 EPS33486.1 - 4.4e-19 68.5 1.4 5.3e-19 68.3 0.0 2.0 2 0 0 2 2 2 1 Proteasome-substrate-size regulator, N-terminal CLASP_N PF12348.8 EPS33486.1 - 2.8e-05 23.8 0.1 0.069 12.7 0.0 3.2 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.22 EPS33486.1 - 0.039 14.2 0.0 5.8 7.5 0.0 4.3 5 0 0 5 5 5 0 HEAT repeat HEAT_2 PF13646.6 EPS33486.1 - 0.086 13.2 0.5 24 5.4 0.0 4.4 5 0 0 5 5 5 0 HEAT repeats DUF3405 PF11885.8 EPS33487.1 - 1.3e-172 575.0 1.3 1.9e-172 574.5 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) SHR-BD PF06650.12 EPS33488.1 - 6.2e-97 324.2 0.2 5.7e-95 317.8 0.0 3.9 4 1 0 4 4 4 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 EPS33488.1 - 4e-93 311.2 15.4 3.7e-88 294.9 0.3 5.9 4 2 1 5 5 5 4 Repeating coiled region of VPS13 VPS13 PF16908.5 EPS33488.1 - 7.5e-82 274.7 1.1 9.2e-81 271.1 0.0 3.3 5 0 0 5 5 5 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 EPS33488.1 - 2.2e-73 245.8 10.1 2.1e-70 236.1 0.5 3.0 3 0 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 EPS33488.1 - 6.7e-41 139.1 0.1 2.5e-40 137.2 0.1 2.1 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 EPS33488.1 - 4.1e-06 27.0 0.0 2.2e-05 24.7 0.0 2.3 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain LEA_2 PF03168.13 EPS33488.1 - 0.15 12.6 0.0 2.6 8.7 0.0 3.2 2 0 0 2 2 2 0 Late embryogenesis abundant protein DUF896 PF05979.12 EPS33488.1 - 2.9 7.8 7.5 21 5.1 1.7 3.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) DUF3429 PF11911.8 EPS33489.1 - 2e-41 141.7 13.8 2.6e-41 141.3 13.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) FGGY_C PF02782.16 EPS33492.1 - 1.5e-73 246.8 1.6 1.9e-73 246.4 0.9 1.5 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EPS33492.1 - 4.9e-60 203.1 0.0 6.5e-60 202.7 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.20 EPS33492.1 - 0.011 15.3 0.2 0.7 9.3 0.0 2.2 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family RhoGEF67_u1 PF16615.5 EPS33492.1 - 0.038 14.5 0.1 0.071 13.6 0.1 1.4 1 0 0 1 1 1 0 Unstructured region one on RhoGEF 6 and 7 Peptidase_M41 PF01434.18 EPS33493.1 - 1.1e-57 195.0 1.2 1.1e-57 195.0 1.2 1.6 2 0 0 2 2 1 1 Peptidase family M41 AAA PF00004.29 EPS33493.1 - 1.7e-43 148.2 0.0 6e-43 146.4 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EPS33493.1 - 2.9e-10 39.8 0.0 8.7e-10 38.2 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EPS33493.1 - 8.2e-06 25.9 0.0 2.6e-05 24.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EPS33493.1 - 5e-05 22.7 0.1 0.00014 21.2 0.0 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_16 PF13191.6 EPS33493.1 - 9.4e-05 22.9 4.2 0.00014 22.3 0.5 3.2 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 EPS33493.1 - 0.00021 21.6 0.2 0.02 15.2 0.2 3.0 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EPS33493.1 - 0.00035 20.4 0.0 0.00096 18.9 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EPS33493.1 - 0.0053 16.9 0.0 0.014 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EPS33493.1 - 0.01 15.6 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.14 EPS33493.1 - 0.017 15.2 0.0 0.069 13.3 0.0 2.1 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 EPS33493.1 - 0.025 14.0 0.3 0.051 13.0 0.3 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EPS33493.1 - 0.026 14.1 1.0 0.72 9.4 0.3 2.6 1 1 1 2 2 2 0 AAA domain DUF815 PF05673.13 EPS33493.1 - 0.035 13.2 0.0 0.079 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 EPS33493.1 - 0.044 14.3 0.0 0.12 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EPS33493.1 - 0.06 13.3 0.4 1.8 8.5 0.1 2.7 2 0 0 2 2 2 0 NACHT domain ATPase PF06745.13 EPS33493.1 - 0.061 12.7 0.9 1.4 8.2 0.0 2.7 3 0 0 3 3 3 0 KaiC AAA_28 PF13521.6 EPS33493.1 - 0.073 13.3 0.3 0.22 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EPS33493.1 - 0.1 13.0 0.3 0.26 11.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 EPS33493.1 - 0.13 12.3 0.0 0.39 10.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_7 PF12775.7 EPS33493.1 - 0.17 11.4 0.1 0.43 10.1 0.1 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 EPS33493.1 - 0.8 9.0 2.8 0.77 9.0 0.5 2.2 2 1 0 2 2 2 0 Zeta toxin NTP_transferase PF00483.23 EPS33496.1 - 3.1e-52 177.6 0.0 6e-52 176.7 0.0 1.4 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.24 EPS33496.1 - 9.8e-14 50.5 15.1 2.8e-11 42.7 5.2 4.0 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EPS33496.1 - 6.6e-10 39.6 0.0 9.9e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 EPS33496.1 - 5.8e-06 26.0 8.1 2.3e-05 24.0 3.9 3.0 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 EPS33496.1 - 0.0011 17.2 0.3 0.0017 16.6 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) IspD PF01128.19 EPS33496.1 - 0.18 11.5 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase adh_short PF00106.25 EPS33497.1 - 3.6e-09 36.4 0.0 0.00057 19.4 0.0 3.1 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 EPS33497.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 KR domain Metal_resist PF13801.6 EPS33497.1 - 0.19 12.0 0.1 0.19 12.0 0.1 1.9 3 0 0 3 3 3 0 Heavy-metal resistance Suc_Fer-like PF06999.12 EPS33498.1 - 9.6e-72 241.0 0.0 1.2e-71 240.7 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like zf-C2H2 PF00096.26 EPS33500.1 - 1e-17 63.5 37.7 3.5e-05 24.0 4.9 5.0 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EPS33500.1 - 1.4e-12 47.4 37.8 3.5e-05 24.0 0.7 5.6 5 1 0 5 5 5 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 EPS33500.1 - 0.051 14.4 3.4 0.051 14.4 3.4 5.6 6 0 0 6 6 6 0 C2H2-type zinc finger TFIIA PF03153.13 EPS33500.1 - 0.75 9.7 23.2 0.88 9.5 23.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Aminotran_1_2 PF00155.21 EPS33503.1 - 3.4e-36 125.2 0.0 4.6e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II PH_10 PF15411.6 EPS33504.1 - 3e-39 134.1 0.0 6.4e-39 133.0 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.11 EPS33504.1 - 1.4e-33 115.0 0.0 2.5e-33 114.2 0.0 1.5 1 0 0 1 1 1 1 CDC24 Calponin RhoGEF PF00621.20 EPS33504.1 - 3.7e-25 89.2 0.7 6e-25 88.5 0.7 1.4 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.24 EPS33504.1 - 1.8e-07 31.0 0.1 4.4e-07 29.8 0.1 1.6 1 0 0 1 1 1 1 PB1 domain bZIP_C PF12498.8 EPS33504.1 - 0.79 10.7 3.1 38 5.3 0.5 3.5 3 0 0 3 3 3 0 Basic leucine-zipper C terminal DUF4404 PF14357.6 EPS33504.1 - 1.5 9.5 5.1 2.1 9.0 0.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) WD40 PF00400.32 EPS33505.1 - 2.8e-32 110.3 13.2 1.6e-05 25.6 0.0 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.7 EPS33505.1 - 1e-11 44.5 0.7 2.9e-11 43.1 0.7 1.9 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 EPS33505.1 - 9.4e-07 29.1 1.9 1.3 9.4 0.0 4.4 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain F-box PF00646.33 EPS33505.1 - 1.3e-06 28.2 0.2 3.2e-06 26.9 0.2 1.7 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.8 EPS33505.1 - 0.00018 20.3 4.5 0.39 9.3 0.0 3.2 2 1 1 3 3 3 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 EPS33505.1 - 0.058 13.4 0.0 18 5.4 0.1 4.1 2 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Uds1 PF15456.6 EPS33507.1 - 2.8e-44 150.4 0.6 2.8e-44 150.4 0.6 6.4 3 2 3 6 6 6 1 Up-regulated During Septation HR1 PF02185.16 EPS33507.1 - 3.5e-05 23.8 0.1 3.5e-05 23.8 0.1 7.7 4 2 3 7 7 7 1 Hr1 repeat GAS PF13851.6 EPS33507.1 - 0.0026 17.2 9.8 0.0026 17.2 9.8 6.4 3 1 2 6 6 6 1 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 EPS33507.1 - 0.014 15.9 16.3 0.014 15.9 16.3 8.5 3 2 5 8 8 8 0 Apg6 coiled-coil region DUF695 PF05117.12 EPS33507.1 - 0.38 10.9 3.9 0.26 11.4 1.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF695) FUSC PF04632.12 EPS33507.1 - 4 5.8 61.3 1.9 6.9 1.0 4.3 2 1 2 4 4 4 0 Fusaric acid resistance protein family DUF4407 PF14362.6 EPS33507.1 - 8 5.7 71.2 0.97 8.7 27.2 4.9 2 1 1 4 4 4 0 Domain of unknown function (DUF4407) Lipoprotein_6 PF01441.19 EPS33507.1 - 9.9 6.1 15.3 0.16 11.9 2.4 3.2 2 1 1 3 3 3 0 Lipoprotein MFS_1 PF07690.16 EPS33508.1 - 1.1e-25 90.3 37.9 1.7e-25 89.7 37.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EPS33508.1 - 2.3 7.0 11.7 0.045 12.6 2.1 2.4 1 1 0 2 2 2 0 MFS_1 like family UCR_hinge PF02320.16 EPS33509.1 - 9.3e-28 96.2 9.4 9.3e-28 96.2 9.4 1.9 2 1 0 2 2 1 1 Ubiquinol-cytochrome C reductase hinge protein Mpp10 PF04006.12 EPS33509.1 - 0.005 15.4 20.7 0.0067 14.9 20.7 1.3 1 0 0 1 1 1 1 Mpp10 protein BUD22 PF09073.10 EPS33509.1 - 0.054 12.8 23.0 0.064 12.6 23.0 1.0 1 0 0 1 1 1 0 BUD22 CPSF100_C PF13299.6 EPS33509.1 - 0.083 13.1 8.4 0.12 12.6 8.4 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RR_TM4-6 PF06459.12 EPS33509.1 - 0.13 12.0 18.8 0.16 11.7 18.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.17 EPS33509.1 - 0.31 11.2 3.8 0.36 11.0 3.8 1.2 1 0 0 1 1 1 0 DDHD domain DUF4471 PF14740.6 EPS33509.1 - 0.6 9.3 5.1 0.81 8.8 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) Tim54 PF11711.8 EPS33509.1 - 0.63 8.8 17.4 0.75 8.5 17.4 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RNA_polI_A34 PF08208.11 EPS33509.1 - 0.69 10.0 20.1 0.96 9.5 20.1 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 SAPS PF04499.15 EPS33509.1 - 0.81 8.4 11.1 0.84 8.3 11.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF913 PF06025.12 EPS33509.1 - 0.95 8.4 9.7 1 8.2 9.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SpoIIIAH PF12685.7 EPS33509.1 - 1.2 9.0 13.4 1.4 8.7 13.4 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Nop14 PF04147.12 EPS33509.1 - 1.3 7.2 24.8 1.4 7.0 24.8 1.0 1 0 0 1 1 1 0 Nop14-like family Neur_chan_memb PF02932.16 EPS33509.1 - 2 8.4 8.0 2.3 8.2 8.0 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4045 PF13254.6 EPS33509.1 - 2.2 7.8 19.2 2.6 7.6 19.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Mitofilin PF09731.9 EPS33509.1 - 2.6 6.8 18.5 3.1 6.5 18.5 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Zip PF02535.22 EPS33509.1 - 3 7.0 10.0 3.3 6.8 10.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter SLC12 PF03522.15 EPS33509.1 - 3.3 6.6 7.9 3.7 6.5 7.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Presenilin PF01080.17 EPS33509.1 - 3.4 6.3 14.2 3.9 6.2 14.2 1.1 1 0 0 1 1 1 0 Presenilin DUF5427 PF10310.9 EPS33509.1 - 4.6 6.1 17.3 5.7 5.8 17.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) CDC45 PF02724.14 EPS33509.1 - 4.8 5.4 18.2 5.2 5.2 18.2 1.1 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.12 EPS33509.1 - 4.9 6.5 29.1 1.9 7.8 27.2 1.3 1 1 0 1 1 1 0 Cobalamin biosynthesis protein CobT SpoIIP PF07454.11 EPS33509.1 - 4.9 6.5 14.4 5.9 6.3 14.4 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Raftlin PF15250.6 EPS33509.1 - 5.9 5.5 12.7 6.6 5.4 12.7 1.0 1 0 0 1 1 1 0 Raftlin PA26 PF04636.13 EPS33509.1 - 7.3 5.4 10.9 8.7 5.1 10.9 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Gti1_Pac2 PF09729.9 EPS33509.1 - 7.7 6.6 7.5 9.4 6.3 7.5 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family PPL5 PF18168.1 EPS33509.1 - 8.1 5.6 8.1 9.1 5.5 8.1 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Sec62 PF03839.16 EPS33509.1 - 9.1 5.7 10.1 12 5.4 10.1 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 NPR3 PF03666.13 EPS33509.1 - 9.5 4.9 13.0 11 4.7 13.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Vps36_ESCRT-II PF11605.8 EPS33510.1 - 0.013 15.7 0.0 0.073 13.3 0.0 1.9 2 0 0 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 Popeye PF04831.13 EPS33511.1 - 1.8 8.7 5.5 3.7 7.7 5.5 1.5 1 0 0 1 1 1 0 Popeye protein conserved region DHHC PF01529.20 EPS33511.1 - 6.3 6.9 12.6 6 7.0 3.6 2.5 1 1 1 2 2 2 0 DHHC palmitoyltransferase Acyltransferase PF01553.21 EPS33512.1 - 1.2e-07 31.4 0.0 0.0016 18.1 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase Prenyltransf PF01255.19 EPS33513.1 - 2.9e-79 265.7 0.0 6.7e-79 264.5 0.0 1.5 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Sacchrp_dh_C PF16653.5 EPS33514.1 - 1.3e-93 313.9 0.0 2.7e-93 312.9 0.0 1.5 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 EPS33514.1 - 8.6e-27 94.0 0.7 1.3e-26 93.4 0.7 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EPS33514.1 - 2e-08 34.4 0.3 4.9e-08 33.1 0.3 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 EPS33514.1 - 6.4e-07 29.5 0.3 1e-06 28.8 0.3 1.3 1 0 0 1 1 1 1 NAD(P)H-binding IlvN PF07991.12 EPS33514.1 - 0.0004 20.0 1.5 0.00073 19.2 0.1 2.1 3 0 0 3 3 3 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 EPS33514.1 - 0.0013 18.0 0.5 0.0021 17.4 0.5 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.17 EPS33514.1 - 0.0027 18.2 0.2 0.006 17.1 0.2 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.19 EPS33514.1 - 0.0028 16.7 0.1 0.004 16.2 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_7 PF13241.6 EPS33514.1 - 0.0045 17.4 0.4 0.0096 16.3 0.4 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding NmrA PF05368.13 EPS33514.1 - 0.0064 16.1 0.5 0.01 15.4 0.5 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EPS33514.1 - 0.0093 15.4 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 EPS33514.1 - 0.027 13.9 0.7 0.044 13.2 0.2 1.5 2 0 0 2 2 2 0 short chain dehydrogenase GFO_IDH_MocA PF01408.22 EPS33514.1 - 0.042 14.7 0.1 0.074 13.9 0.1 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold adh_short_C2 PF13561.6 EPS33514.1 - 0.068 12.7 0.5 0.13 11.8 0.5 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase 2-Hacid_dh_C PF02826.19 EPS33514.1 - 0.1 11.9 0.1 0.21 11.0 0.1 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_3 PF03447.16 EPS33514.1 - 0.14 12.8 0.5 0.25 12.0 0.5 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Aha1_N PF09229.11 EPS33515.1 - 4.8e-42 143.4 0.8 9.5e-42 142.5 0.8 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 EPS33515.1 - 1.5e-22 80.2 0.5 4.1e-22 78.7 0.2 1.8 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Med18 PF09637.10 EPS33515.1 - 0.036 13.9 0.6 0.099 12.5 0.6 1.8 1 1 0 1 1 1 0 Med18 protein MARVEL PF01284.23 EPS33517.1 - 3.3e-12 46.7 14.6 4.2e-12 46.3 14.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain PIG-U PF06728.13 EPS33517.1 - 0.016 14.2 5.6 0.024 13.7 5.6 1.3 1 0 0 1 1 1 0 GPI transamidase subunit PIG-U DUF4199 PF13858.6 EPS33517.1 - 0.017 15.5 6.6 0.04 14.3 6.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) Phage_holin_2_1 PF04971.12 EPS33517.1 - 0.22 11.5 2.1 5.2 7.2 0.0 2.4 2 0 0 2 2 2 0 Bacteriophage P21 holin S ABC2_membrane_2 PF12679.7 EPS33517.1 - 0.57 9.4 7.5 1 8.6 7.5 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein FBPase PF00316.20 EPS33519.1 - 4.9e-68 228.3 0.0 8.4e-68 227.6 0.0 1.4 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain V_ATPase_I PF01496.19 EPS33520.1 - 0 1056.4 0.0 0 1056.2 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF1515 PF07439.11 EPS33520.1 - 0.0058 16.7 0.1 0.015 15.3 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1515) CheZ PF04344.13 EPS33520.1 - 0.026 14.4 0.7 0.21 11.5 0.1 2.4 2 1 0 2 2 2 0 Chemotaxis phosphatase, CheZ Big_8 PF17961.1 EPS33520.1 - 0.062 13.4 0.0 8.1 6.6 0.0 2.5 2 0 0 2 2 2 0 Bacterial Ig domain DivIC PF04977.15 EPS33520.1 - 0.086 12.6 0.3 0.41 10.4 0.3 2.2 1 0 0 1 1 1 0 Septum formation initiator Filament PF00038.21 EPS33520.1 - 0.14 11.7 0.7 6.1 6.3 0.2 2.2 2 0 0 2 2 2 0 Intermediate filament protein DUF1664 PF07889.12 EPS33520.1 - 0.21 11.6 1.2 5.3 7.1 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Tektin PF03148.14 EPS33520.1 - 0.23 10.2 5.2 1.6 7.4 1.7 2.4 2 1 0 2 2 2 0 Tektin family DUF3552 PF12072.8 EPS33520.1 - 0.23 10.8 0.8 16 4.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DASH_Dam1 PF08653.10 EPS33520.1 - 0.24 11.3 0.9 68 3.4 0.0 3.9 4 0 0 4 4 4 0 DASH complex subunit Dam1 CdvA PF18822.1 EPS33520.1 - 0.31 10.9 2.9 42 4.0 0.0 3.3 3 0 0 3 3 3 0 CdvA-like coiled-coil domain F-box PF00646.33 EPS33521.1 - 0.009 15.9 0.0 0.029 14.2 0.0 1.9 1 0 0 1 1 1 1 F-box domain Inhibitor_I10 PF12559.8 EPS33521.1 - 0.13 12.6 0.0 0.32 11.3 0.0 1.6 1 0 0 1 1 1 0 Serine endopeptidase inhibitors Acetyltransf_3 PF13302.7 EPS33522.1 - 5.5e-29 101.6 0.0 6.6e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPS33522.1 - 0.00025 21.3 0.0 0.00048 20.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EPS33522.1 - 0.099 13.1 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pkinase_C PF00433.24 EPS33523.1 - 0.047 14.4 0.2 0.093 13.4 0.0 1.5 2 0 0 2 2 2 0 Protein kinase C terminal domain VPS9 PF02204.18 EPS33524.1 - 6.4e-30 103.5 0.0 1.5e-29 102.3 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 EPS33524.1 - 1.5e-15 57.2 1.1 1.5e-14 54.0 0.3 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF5601) CUE PF02845.16 EPS33524.1 - 7.1e-10 38.4 0.3 9.4e-09 34.8 0.0 2.4 2 0 0 2 2 2 1 CUE domain Asn_synthase PF00733.21 EPS33525.1 - 1.1e-16 61.5 3.9 9.7e-07 28.8 0.0 3.1 2 1 1 3 3 3 3 Asparagine synthase GATase_7 PF13537.6 EPS33525.1 - 4.4e-08 33.1 0.0 1.6e-07 31.3 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EPS33525.1 - 4.9e-06 26.2 0.0 8.4e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein GATase_6 PF13522.6 EPS33525.1 - 2.1e-05 24.7 0.0 4.9e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain bZIP_2 PF07716.15 EPS33526.1 - 3.1e-06 27.2 6.3 5.5e-06 26.4 6.3 1.4 1 0 0 1 1 1 1 Basic region leucine zipper PKcGMP_CC PF16808.5 EPS33526.1 - 7.1e-05 22.6 0.3 0.00013 21.7 0.3 1.4 1 0 0 1 1 1 1 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF4407 PF14362.6 EPS33526.1 - 0.051 12.9 2.7 0.076 12.4 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sec2p PF06428.11 EPS33526.1 - 0.063 13.3 2.6 0.14 12.1 2.6 1.6 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p bZIP_1 PF00170.21 EPS33526.1 - 0.064 13.4 9.0 0.11 12.6 9.0 1.3 1 0 0 1 1 1 0 bZIP transcription factor bZIP_Maf PF03131.17 EPS33526.1 - 2.6 8.6 8.0 6.1 7.4 8.0 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor PH_6 PF15406.6 EPS33528.1 - 4.2e-36 123.6 2.1 4.2e-36 123.6 2.1 2.9 3 0 0 3 3 3 1 Pleckstrin homology domain PH PF00169.29 EPS33528.1 - 7.6e-07 29.6 0.0 2.7e-06 27.9 0.0 1.9 1 1 0 1 1 1 1 PH domain DCP1 PF06058.13 EPS33528.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Dcp1-like decapping family TIMELESS PF04821.14 EPS33528.1 - 0.76 9.0 5.2 1.6 8.0 1.7 2.4 2 0 0 2 2 2 0 Timeless protein PH_13 PF16652.5 EPS33528.1 - 0.92 9.3 6.1 0.12 12.2 0.3 2.3 1 1 1 2 2 2 0 Pleckstrin homology domain Ank_2 PF12796.7 EPS33532.1 - 7e-58 193.2 0.0 1.4e-09 38.4 0.0 6.7 5 1 2 7 7 7 7 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EPS33532.1 - 4.9e-44 147.8 9.7 5.8e-06 26.5 0.0 9.5 7 3 2 9 9 9 8 Ankyrin repeats (many copies) Ank_4 PF13637.6 EPS33532.1 - 2e-42 143.0 8.6 7.5e-07 29.6 0.1 11.8 4 4 7 12 12 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPS33532.1 - 2.7e-33 110.2 10.8 9.7e-05 22.5 0.0 14.5 16 0 0 16 16 16 6 Ankyrin repeat Ank PF00023.30 EPS33532.1 - 6.9e-26 89.5 19.1 0.0019 18.5 0.0 12.6 13 0 0 13 13 13 7 Ankyrin repeat SRC-1 PF08832.10 EPS33532.1 - 0.54 11.3 2.6 0.62 11.2 0.2 2.4 2 0 0 2 2 2 0 Steroid receptor coactivator FCD PF07729.12 EPS33532.1 - 0.63 10.5 4.7 22 5.5 0.0 4.3 3 1 1 4 4 4 0 FCD domain GCV_T PF01571.21 EPS33533.1 - 5.8e-72 242.1 0.0 9.8e-72 241.4 0.0 1.4 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DAO PF01266.24 EPS33533.1 - 1.3e-46 159.9 0.3 1.9e-46 159.3 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T_C PF08669.11 EPS33533.1 - 4.2e-21 74.7 0.0 9.5e-21 73.5 0.0 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain FAO_M PF16350.5 EPS33533.1 - 1.3e-17 63.8 0.0 2.6e-17 62.9 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase central domain Pyr_redox_2 PF07992.14 EPS33533.1 - 6.2e-05 22.4 0.0 0.017 14.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPS33533.1 - 0.00045 20.7 0.0 0.0092 16.5 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SoxG PF04268.12 EPS33533.1 - 0.00046 20.4 0.0 0.0073 16.5 0.0 2.8 3 0 0 3 3 3 1 Sarcosine oxidase, gamma subunit family TrkA_N PF02254.18 EPS33533.1 - 0.0012 19.1 0.7 0.011 16.0 0.2 2.5 3 0 0 3 3 3 1 TrkA-N domain Shikimate_DH PF01488.20 EPS33533.1 - 0.0048 17.0 0.2 0.0091 16.1 0.2 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 EPS33533.1 - 0.006 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 ThiF family Trp_halogenase PF04820.14 EPS33533.1 - 0.15 10.9 0.1 1.7 7.4 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase DUF4235 PF14019.6 EPS33533.1 - 1.7 8.8 5.0 4.3 7.5 0.0 3.5 5 0 0 5 5 5 0 Protein of unknown function (DUF4235) Sulfate_transp PF00916.20 EPS33534.1 - 1.7e-64 218.0 25.0 2.8e-64 217.2 25.0 1.3 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 EPS33534.1 - 2.3e-14 53.2 0.0 4.5e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 EPS33534.1 - 4.2e-10 39.3 0.0 8.7e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 STAS domain DUF3481 PF11980.8 EPS33534.1 - 8.1 6.2 5.6 3.1 7.6 0.5 2.4 2 0 0 2 2 2 0 C-terminal domain of neuropilin glycoprotein DUF669 PF05037.13 EPS33535.1 - 0.11 12.6 0.0 0.14 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF669) Sld5 PF05916.11 EPS33536.1 - 9.7e-14 51.8 0.0 1.6e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein FliT PF05400.13 EPS33536.1 - 0.049 14.5 0.0 0.55 11.1 0.0 2.6 3 0 0 3 3 3 0 Flagellar protein FliT Granulin PF00396.18 EPS33537.1 - 9.2 6.7 20.1 85 3.6 0.2 4.1 2 1 1 3 3 3 0 Granulin CYYR1 PF10873.8 EPS33538.1 - 0.0024 18.4 0.1 0.0024 18.4 0.1 2.4 2 1 1 3 3 3 1 Cysteine and tyrosine-rich protein 1 Insulin_TMD PF17870.1 EPS33538.1 - 0.17 12.0 2.5 0.52 10.4 2.5 1.8 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Rcd1 PF04078.13 EPS33539.1 - 4.7e-126 419.4 3.0 5.7e-126 419.1 3.0 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Lin-8 PF03353.15 EPS33539.1 - 0.23 11.0 7.9 0.31 10.6 7.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist TFIIA PF03153.13 EPS33539.1 - 0.33 10.9 22.2 0.4 10.6 22.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 EPS33539.1 - 0.42 8.8 14.7 0.48 8.6 14.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 baeRF_family10 PF18854.1 EPS33539.1 - 1.7 8.9 11.8 13 6.0 8.3 2.5 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 10 ThylakoidFormat PF11264.8 EPS33539.1 - 8.2 6.0 8.3 45 3.6 7.2 2.4 3 0 0 3 3 3 0 Thylakoid formation protein PHD PF00628.29 EPS33540.1 - 6.2e-08 32.4 10.5 6.2e-08 32.4 10.5 1.9 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 EPS33540.1 - 0.0015 18.0 4.8 0.0015 18.0 4.8 1.9 2 0 0 2 2 2 1 PHD-finger zinc_ribbon_10 PF10058.9 EPS33540.1 - 0.14 11.9 2.8 1.1 9.0 1.6 2.3 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF4662 PF15578.6 EPS33540.1 - 2.8 7.7 9.2 6.1 6.5 9.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) HMG_box PF00505.19 EPS33544.1 - 4.3e-13 49.5 0.0 2.5e-12 47.0 0.0 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box MATalpha_HMGbox PF04769.12 EPS33544.1 - 0.16 11.2 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Mating-type protein MAT alpha 1 HMG-box Prefoldin_2 PF01920.20 EPS33545.1 - 1.2e-19 70.2 1.2 1.5e-19 69.9 1.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit UBA_2 PF08587.11 EPS33548.1 - 0.12 12.5 3.4 0.096 12.8 0.9 2.3 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) Mito_carr PF00153.27 EPS33549.1 - 2e-51 171.9 4.0 2.1e-17 62.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ceramidase PF05875.12 EPS33550.1 - 1.1e-103 346.2 11.6 1.3e-103 346.0 11.6 1.0 1 0 0 1 1 1 1 Ceramidase Abhydrolase_6 PF12697.7 EPS33551.1 - 4.7e-13 50.2 3.0 8.9e-13 49.3 3.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPS33551.1 - 5.9e-07 29.0 0.0 8.6e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EPS33551.1 - 0.00083 19.1 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 EPS33551.1 - 0.031 13.2 0.0 0.053 12.4 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme PGAP1 PF07819.13 EPS33551.1 - 0.095 12.4 0.0 0.21 11.3 0.1 1.5 2 0 0 2 2 2 0 PGAP1-like protein TFIID_20kDa PF03847.13 EPS33552.1 - 0.17 12.4 0.0 1.3 9.6 0.0 2.0 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A PTCB-BRCT PF12738.7 EPS33553.1 - 5e-36 122.5 3.9 2.9e-20 72.0 0.2 5.5 6 0 0 6 6 6 4 twin BRCT domain RTT107_BRCT_5 PF16770.5 EPS33553.1 - 7.7e-35 118.8 0.1 3.8e-31 106.9 0.0 4.2 4 0 0 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 EPS33553.1 - 1.6e-28 98.9 0.0 1.6e-07 31.6 0.0 6.4 6 1 0 6 6 6 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EPS33553.1 - 1.6e-27 95.7 0.0 2.1e-05 24.9 0.0 5.8 5 0 0 5 5 5 5 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EPS33553.1 - 1.3e-11 44.6 0.0 0.0053 17.0 0.0 3.8 4 0 0 4 4 4 3 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 EPS33553.1 - 9e-06 25.7 0.0 0.026 14.6 0.0 3.7 4 0 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain ESCRT-II PF05871.12 EPS33554.1 - 2.2e-53 180.2 0.1 2.9e-53 179.9 0.1 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit Methyltransf_4 PF02390.17 EPS33555.1 - 2.3e-43 147.7 0.6 1.3e-29 102.9 0.2 3.1 2 1 0 2 2 2 2 Putative methyltransferase Methyltransf_25 PF13649.6 EPS33555.1 - 0.00016 22.3 0.0 0.0024 18.5 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain MTS PF05175.14 EPS33555.1 - 0.00074 19.1 0.0 0.033 13.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_12 PF08242.12 EPS33555.1 - 0.0058 17.3 0.0 0.019 15.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS33555.1 - 0.024 15.3 0.0 2.6 8.8 0.0 3.1 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_31 PF13847.6 EPS33555.1 - 0.07 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain LIM PF00412.22 EPS33556.1 - 5.1e-27 93.9 21.4 3.7e-10 39.9 3.0 3.6 3 1 0 3 3 3 3 LIM domain DUF4680 PF15730.5 EPS33556.1 - 0.018 15.4 2.0 0.018 15.4 2.0 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF4680) Zn_ribbon_recom PF13408.6 EPS33556.1 - 0.048 14.2 0.1 0.048 14.2 0.1 3.2 4 0 0 4 4 4 0 Recombinase zinc beta ribbon domain ArgoN PF16486.5 EPS33556.1 - 0.16 12.6 0.3 0.46 11.1 0.3 1.9 1 1 0 1 1 1 0 N-terminal domain of argonaute MFS_1 PF07690.16 EPS33557.1 - 1.7e-22 79.8 48.1 1.5e-21 76.7 49.8 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EPS33557.1 - 2.5 6.8 27.1 0.14 11.0 1.3 2.7 2 1 1 3 3 3 0 MFS_1 like family RNB PF00773.19 EPS33558.1 - 1.6e-99 333.3 0.0 2.8e-99 332.6 0.0 1.3 1 0 0 1 1 1 1 RNB domain Rrp44_CSD1 PF17216.3 EPS33558.1 - 6.2e-33 113.6 0.0 1.5e-32 112.4 0.0 1.7 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 EPS33558.1 - 2e-28 98.2 0.6 5.3e-28 96.8 0.6 1.7 1 0 0 1 1 1 1 S1 domain OB_Dis3 PF17849.1 EPS33558.1 - 2.2e-20 72.4 0.0 4.9e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 EPS33558.1 - 7.4e-11 42.5 0.1 1.6e-10 41.4 0.1 1.6 1 0 0 1 1 1 1 PIN domain CSD2 PF17876.1 EPS33558.1 - 6.8e-07 29.4 0.0 0.00027 21.0 0.0 3.0 2 0 0 2 2 2 2 Cold shock domain CN_hydrolase PF00795.22 EPS33559.1 - 6.1e-56 189.6 0.0 6.9e-56 189.5 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase ESSS PF10183.9 EPS33560.1 - 1.4e-18 67.1 0.0 1.5e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Dna2 PF08696.11 EPS33561.1 - 3.9e-70 235.8 0.7 7.5e-70 234.9 0.7 1.5 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 EPS33561.1 - 1.5e-53 181.4 0.0 2.6e-53 180.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EPS33561.1 - 1.5e-32 113.4 0.1 4.7e-16 59.4 0.0 2.7 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 EPS33561.1 - 1.9e-15 57.1 0.0 3.7e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EPS33561.1 - 1.1e-12 48.4 0.1 2.6e-12 47.3 0.1 1.7 1 0 0 1 1 1 1 AAA domain Cas_Cas4 PF01930.17 EPS33561.1 - 2.2e-08 34.4 0.1 4.4e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF83 PDDEXK_1 PF12705.7 EPS33561.1 - 5.2e-08 33.1 0.0 1e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.18 EPS33561.1 - 4e-06 26.8 2.0 0.47 10.1 0.0 3.6 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.14 EPS33561.1 - 8.5e-05 22.5 0.0 0.00039 20.3 0.0 2.1 2 0 0 2 2 2 1 Helicase UvrD-helicase PF00580.21 EPS33561.1 - 0.00028 20.5 0.1 0.00028 20.5 0.1 2.7 4 0 0 4 4 4 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.6 EPS33561.1 - 0.00065 20.1 0.0 0.013 15.9 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain SRP54 PF00448.22 EPS33561.1 - 0.00093 18.9 0.0 0.0022 17.6 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain CbiA PF01656.23 EPS33561.1 - 0.0043 17.1 0.0 0.02 14.9 0.0 2.2 2 0 0 2 2 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain PIF1 PF05970.14 EPS33561.1 - 0.0097 15.1 0.2 0.048 12.8 0.2 2.0 1 1 0 1 1 1 1 PIF1-like helicase ResIII PF04851.15 EPS33561.1 - 0.016 15.2 0.0 0.049 13.6 0.0 1.9 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 EPS33561.1 - 0.033 13.7 0.1 0.088 12.3 0.1 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 EPS33561.1 - 0.054 14.1 0.2 0.87 10.1 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.6 EPS33561.1 - 0.054 13.1 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EPS33561.1 - 0.07 12.4 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF87 PF01935.17 EPS33561.1 - 0.076 13.1 1.1 0.19 11.8 0.3 2.1 2 0 0 2 2 2 0 Helicase HerA, central domain MeaB PF03308.16 EPS33561.1 - 0.082 11.9 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 EPS33561.1 - 0.13 12.1 0.8 0.61 10.0 0.2 2.3 2 0 0 2 2 2 0 NTPase cobW PF02492.19 EPS33561.1 - 0.14 11.8 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 EPS33561.1 - 0.17 12.3 0.0 0.42 11.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF1507 PF07408.11 EPS33561.1 - 0.17 11.8 0.0 0.93 9.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1507) Ribonuc_P_40 PF08584.11 EPS33562.1 - 1.2e-68 231.5 0.0 1.8e-68 230.9 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit WD40 PF00400.32 EPS33563.1 - 4e-25 87.6 11.3 8.7e-07 29.6 0.0 7.4 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS33563.1 - 3.6e-17 62.4 0.0 0.0056 16.9 0.0 6.3 2 2 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EPS33563.1 - 4.5e-09 35.3 0.0 4.4e-06 25.5 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.11 EPS33563.1 - 3.1e-05 23.9 0.0 0.21 11.5 0.0 3.0 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A PALB2_WD40 PF16756.5 EPS33563.1 - 0.003 16.6 0.5 0.0062 15.5 0.0 1.6 2 0 0 2 2 2 1 Partner and localizer of BRCA2 WD40 domain PD40 PF07676.12 EPS33563.1 - 0.0049 16.8 1.7 10 6.2 0.0 4.3 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat Nup160 PF11715.8 EPS33563.1 - 0.023 13.4 0.6 0.25 9.9 0.2 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.14 EPS33563.1 - 0.33 9.9 0.0 1.1 8.2 0.0 1.9 2 0 0 2 2 2 0 Coatomer WD associated region Fungal_trans PF04082.18 EPS33564.1 - 1.5e-21 76.6 0.2 2.7e-21 75.8 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS33564.1 - 2.6e-09 37.0 9.7 5.2e-09 36.1 9.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF655 PF04919.12 EPS33564.1 - 0.062 13.2 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF655) Ribosomal_L2_C PF03947.18 EPS33565.1 - 3.3e-50 169.5 0.7 3.3e-50 169.5 0.7 2.6 2 1 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EPS33565.1 - 2.1e-24 85.3 0.2 3.7e-24 84.5 0.2 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Cyclin_N PF00134.23 EPS33566.1 - 5.2e-46 155.5 0.1 5.5e-45 152.2 0.1 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EPS33566.1 - 4.4e-35 120.3 0.0 7.7e-35 119.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain HIT PF01230.23 EPS33567.1 - 3.1e-18 66.3 0.1 6.8e-18 65.2 0.1 1.5 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.8 EPS33567.1 - 3.2e-06 27.6 0.1 5.2e-06 26.9 0.1 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 EPS33567.1 - 9.8e-05 22.2 0.6 0.00039 20.3 0.1 2.2 2 1 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 Headcase PF16002.5 EPS33567.1 - 0.21 11.0 0.0 0.33 10.4 0.0 1.2 1 0 0 1 1 1 0 Headcase protein UPF0020 PF01170.18 EPS33568.1 - 2.1e-08 34.1 0.0 2.2e-07 30.8 0.0 2.2 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 EPS33568.1 - 0.0053 16.1 0.0 0.0083 15.4 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase N6_N4_Mtase PF01555.18 EPS33568.1 - 0.048 13.4 0.0 0.38 10.4 0.0 2.2 2 0 0 2 2 2 0 DNA methylase SIR2 PF02146.17 EPS33569.1 - 4.1e-59 199.4 0.0 6.5e-59 198.8 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 EPS33569.1 - 0.011 15.4 0.1 1.6 8.5 0.1 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain DUF592 PF04574.13 EPS33569.1 - 0.069 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF592) Fer4_18 PF13746.6 EPS33569.1 - 0.15 12.2 0.1 0.26 11.5 0.1 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain TPR_8 PF13181.6 EPS33570.1 - 8.1e-09 35.0 0.8 0.0035 17.4 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EPS33570.1 - 1.6e-06 28.6 6.4 0.002 18.7 0.3 3.3 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EPS33570.1 - 2.7e-06 27.6 7.6 4.3e-05 23.7 0.4 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EPS33570.1 - 1.6e-05 25.3 8.6 0.52 11.3 1.2 5.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EPS33570.1 - 2.8e-05 23.6 4.3 0.00031 20.2 0.2 2.4 2 1 0 2 2 2 1 MalT-like TPR region TPR_2 PF07719.17 EPS33570.1 - 3.4e-05 23.6 12.0 0.0088 16.1 0.0 5.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 EPS33570.1 - 4.4e-05 23.9 10.8 0.05 14.1 0.8 3.8 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 EPS33570.1 - 0.00011 21.8 3.6 0.05 13.5 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EPS33570.1 - 0.00038 20.6 0.3 4.5 7.6 0.0 3.4 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 EPS33570.1 - 0.00058 19.5 1.6 0.8 9.4 0.0 4.4 5 0 0 5 5 5 1 TPR repeat TPR_9 PF13371.6 EPS33570.1 - 0.002 18.3 3.5 1.8 8.8 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat HEAT_2 PF13646.6 EPS33570.1 - 0.015 15.6 4.6 0.72 10.3 0.3 3.2 2 1 0 2 2 2 0 HEAT repeats TPR_17 PF13431.6 EPS33570.1 - 0.032 14.6 1.7 45 4.8 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EPS33570.1 - 0.16 11.6 3.0 1 9.0 0.9 3.1 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_6 PF13174.6 EPS33570.1 - 0.35 11.6 7.1 1.8e+02 3.1 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 EPS33570.1 - 0.82 9.8 2.9 9.6 6.5 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat RWD PF05773.22 EPS33571.1 - 3.6e-24 85.3 1.1 7.6e-24 84.2 1.1 1.5 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 EPS33571.1 - 0.0012 19.2 17.3 0.0019 18.6 15.8 2.1 1 1 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 Phage_integrase PF00589.22 EPS33571.1 - 0.01 15.6 0.6 0.014 15.2 0.6 1.2 1 0 0 1 1 1 0 Phage integrase family NPR1_interact PF15699.5 EPS33571.1 - 0.42 11.3 17.3 0.2 12.3 15.0 1.6 1 1 0 1 1 1 0 NPR1 interacting AAA_11 PF13086.6 EPS33571.1 - 0.74 9.6 6.2 1 9.1 6.2 1.1 1 0 0 1 1 1 0 AAA domain Folliculin PF11704.8 EPS33571.1 - 0.84 9.5 3.7 1.1 9.1 3.7 1.2 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport AAA_23 PF13476.6 EPS33571.1 - 6.4 7.2 13.9 10 6.6 13.9 1.3 1 0 0 1 1 1 0 AAA domain UQ_con PF00179.26 EPS33573.1 - 3.1e-17 62.5 0.0 3.5e-17 62.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EPS33573.1 - 0.13 12.6 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 RWD domain DCB PF16213.5 EPS33574.1 - 9.5e-43 145.9 1.3 5.5e-42 143.4 0.8 2.4 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 EPS33574.1 - 1.6e-41 141.8 9.7 1.6e-39 135.3 0.6 5.1 5 1 1 6 6 6 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 EPS33574.1 - 2.6e-20 72.2 1.4 6.9e-20 70.8 1.4 1.7 1 0 0 1 1 1 1 C-terminal region of Mon2 protein DUF1981 PF09324.10 EPS33574.1 - 0.00085 19.1 1.9 0.098 12.5 0.0 4.9 7 0 0 7 7 7 1 Domain of unknown function (DUF1981) Ipi1_N PF12333.8 EPS33574.1 - 0.0095 16.5 0.3 1.5 9.5 0.1 3.8 3 0 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation Vps26 PF03643.15 EPS33575.1 - 1.7e-129 430.7 0.2 2.1e-129 430.4 0.2 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 EPS33575.1 - 0.00026 21.1 0.1 0.69 10.0 0.0 3.0 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EPS33575.1 - 0.013 15.9 0.1 0.21 12.0 0.0 2.6 2 2 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain SKI PF01202.22 EPS33576.1 - 8.1e-13 48.8 0.0 1.4e-12 48.0 0.0 1.3 1 1 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.6 EPS33576.1 - 1e-09 38.7 0.0 1.4e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EPS33576.1 - 5e-09 36.8 0.0 2.4e-08 34.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 EPS33576.1 - 1.5e-06 28.2 0.0 0.025 14.4 0.0 2.1 2 0 0 2 2 2 2 Deoxynucleoside kinase AAA_17 PF13207.6 EPS33576.1 - 0.00011 22.6 1.7 0.015 15.7 1.0 3.0 1 1 1 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 EPS33576.1 - 0.00013 21.8 0.0 0.0059 16.4 0.0 2.1 2 0 0 2 2 2 1 Cytidylate kinase Rad17 PF03215.15 EPS33576.1 - 0.00026 21.0 0.0 0.0007 19.6 0.0 1.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 EPS33576.1 - 0.012 15.9 0.1 0.035 14.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EPS33576.1 - 0.019 15.4 0.0 0.08 13.3 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA PF00004.29 EPS33576.1 - 0.028 14.8 0.0 0.061 13.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EPS33576.1 - 0.041 14.3 0.1 0.064 13.6 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain CoaE PF01121.20 EPS33576.1 - 0.062 13.0 0.1 0.14 11.8 0.0 1.6 2 0 0 2 2 2 0 Dephospho-CoA kinase Zeta_toxin PF06414.12 EPS33576.1 - 0.11 11.7 0.1 0.4 9.9 0.1 1.9 1 1 0 1 1 1 0 Zeta toxin AAA_28 PF13521.6 EPS33576.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EPS33576.1 - 0.17 11.6 0.1 0.28 10.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EPS33576.1 - 0.18 12.3 0.2 0.72 10.4 0.0 1.9 2 0 0 2 2 2 0 ABC transporter RsgA_GTPase PF03193.16 EPS33576.1 - 0.19 11.7 0.1 0.41 10.5 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase Thymidylate_kin PF02223.17 EPS33576.1 - 0.26 11.0 0.7 0.96 9.1 0.0 1.9 2 0 0 2 2 2 0 Thymidylate kinase 2-oxoacid_dh PF00198.23 EPS33577.1 - 4.9e-80 268.3 0.1 7.1e-80 267.8 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EPS33577.1 - 5.3e-14 51.8 0.0 1.1e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EPS33577.1 - 2.7e-11 43.6 0.1 5.5e-11 42.6 0.1 1.6 1 0 0 1 1 1 1 e3 binding domain Grg1 PF11034.8 EPS33578.1 - 6.7e-31 106.3 13.6 7.6e-31 106.2 13.6 1.0 1 0 0 1 1 1 1 Glucose-repressible protein Grg1 KGG PF10685.9 EPS33579.1 - 3.2e-23 81.2 21.9 4.7e-10 39.4 0.8 3.1 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif AAA PF00004.29 EPS33581.1 - 1.1e-14 55.0 0.0 2e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EPS33581.1 - 2.3e-05 24.4 0.0 4.3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EPS33581.1 - 5e-05 23.6 0.0 0.00016 22.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EPS33581.1 - 0.0007 20.0 0.0 0.0016 18.8 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.21 EPS33581.1 - 0.021 14.2 0.1 0.042 13.2 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 EPS33581.1 - 0.043 13.6 0.0 0.084 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EPS33581.1 - 0.086 12.6 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EPS33581.1 - 0.086 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 EPS33581.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 EPS33581.1 - 0.13 12.4 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain HU-CCDC81_bac_2 PF18175.1 EPS33581.1 - 0.15 12.0 0.0 5.4 7.0 0.0 2.3 2 0 0 2 2 2 0 CCDC81-like prokaryotic HU domain 2 TIP49 PF06068.13 EPS33581.1 - 0.25 10.5 0.0 0.38 9.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Mito_fiss_reg PF05308.11 EPS33581.1 - 2 8.4 8.8 2.9 7.9 8.8 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator PI-PLC-X PF00388.19 EPS33582.1 - 1.8e-09 37.3 0.0 3e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Ribosomal_L10 PF00466.20 EPS33583.1 - 0.012 15.7 0.0 0.071 13.3 0.0 2.2 2 1 0 2 2 2 0 Ribosomal protein L10 Glycos_transf_3 PF00591.21 EPS33584.1 - 1.2e-53 182.3 0.0 1.5e-51 175.5 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 EPS33584.1 - 6.1e-08 32.4 0.5 1.3e-07 31.3 0.5 1.5 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain DNA_RNApol_7kD PF03604.13 EPS33585.1 - 1.6e-15 56.5 7.2 2e-15 56.2 7.2 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DUF2197 PF09963.9 EPS33585.1 - 0.00091 19.4 2.1 0.056 13.7 0.1 2.1 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2197) HypA PF01155.19 EPS33585.1 - 0.00098 19.1 0.1 0.001 19.1 0.1 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbon_6 PF10005.9 EPS33585.1 - 0.0027 18.3 0.5 0.0035 18.0 0.5 1.2 1 0 0 1 1 1 1 zinc-ribbon domain DUF2757 PF10955.8 EPS33585.1 - 0.004 17.4 0.3 0.005 17.1 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2757) DZR PF12773.7 EPS33585.1 - 0.011 15.7 0.4 0.016 15.2 0.4 1.2 1 0 0 1 1 1 0 Double zinc ribbon DUF1451 PF07295.11 EPS33585.1 - 0.014 15.4 0.6 0.018 15.1 0.6 1.1 1 0 0 1 1 1 0 Zinc-ribbon containing domain GFA PF04828.14 EPS33585.1 - 0.031 14.6 1.3 4.2 7.8 0.1 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zinc_ribbon_10 PF10058.9 EPS33585.1 - 0.038 13.7 0.2 0.7 9.7 0.0 2.1 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein zf_UBZ PF18439.1 EPS33585.1 - 0.051 13.2 2.7 2.1 8.0 0.3 2.2 1 1 1 2 2 2 0 Ubiquitin-Binding Zinc Finger DUF35_N PF12172.8 EPS33585.1 - 0.088 12.7 1.5 1.7 8.6 0.1 2.3 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) zinc_ribbon_13 PF09855.9 EPS33585.1 - 0.12 12.5 1.3 0.13 12.4 0.1 1.7 1 1 0 1 1 1 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Zn-ribbon_8 PF09723.10 EPS33585.1 - 0.25 11.5 3.7 0.87 9.8 3.4 1.9 1 1 2 3 3 3 0 Zinc ribbon domain Rubredoxin_2 PF18073.1 EPS33585.1 - 0.25 11.1 3.1 4.1 7.2 0.3 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain Zn_ribbon_recom PF13408.6 EPS33585.1 - 0.59 10.7 6.9 0.59 10.7 0.8 2.2 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain Fe_hyd_lg_C PF02906.14 EPS33586.1 - 5.7e-50 170.3 0.0 1.5e-49 168.9 0.0 1.8 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain SLIDE PF09111.10 EPS33586.1 - 0.094 12.7 0.0 0.27 11.2 0.0 1.7 2 0 0 2 2 2 0 SLIDE DUF2263 PF10021.9 EPS33587.1 - 2.1e-15 57.4 0.0 4.8e-15 56.2 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.21 EPS33587.1 - 0.046 13.8 0.0 0.084 12.9 0.0 1.4 1 0 0 1 1 1 0 Macro domain Fapy_DNA_glyco PF01149.24 EPS33588.1 - 5.6e-34 117.2 0.1 1.3e-33 116.1 0.0 1.6 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.14 EPS33588.1 - 1.2e-21 76.4 0.0 2.5e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.11 EPS33588.1 - 0.00042 19.2 0.0 0.00073 18.4 0.0 1.4 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DTHCT PF08070.11 EPS33588.1 - 0.02 15.6 12.9 0.046 14.4 12.9 1.7 1 0 0 1 1 1 0 DTHCT (NUC029) region Ribosomal_S13 PF00416.22 EPS33588.1 - 0.055 13.9 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S13/S18 Cid2 PF09774.9 EPS33589.1 - 3.8e-55 186.7 0.4 4.5e-55 186.5 0.4 1.0 1 0 0 1 1 1 1 Caffeine-induced death protein 2 NARP1 PF12569.8 EPS33590.1 - 9.7e-219 727.5 22.3 2.6e-215 716.2 17.6 2.2 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 EPS33590.1 - 3.5e-18 64.2 29.9 8.1e-05 22.4 0.5 11.4 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_19 PF14559.6 EPS33590.1 - 1.2e-16 61.0 21.9 0.011 16.3 0.5 7.7 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_16 PF13432.6 EPS33590.1 - 1.2e-14 54.7 23.9 0.00076 20.1 0.3 9.7 10 1 1 11 11 10 3 Tetratricopeptide repeat TPR_14 PF13428.6 EPS33590.1 - 7.6e-14 51.2 24.1 0.019 15.7 0.2 11.3 10 2 3 13 13 12 4 Tetratricopeptide repeat TPR_1 PF00515.28 EPS33590.1 - 1.8e-11 43.3 22.8 1.5e-05 24.6 0.4 9.5 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_11 PF13414.6 EPS33590.1 - 2.6e-09 36.6 13.1 4.5e-05 23.0 0.1 6.1 6 0 0 6 6 6 2 TPR repeat TPR_12 PF13424.6 EPS33590.1 - 1.2e-08 35.1 24.0 0.45 10.8 0.4 7.8 6 1 0 7 7 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 EPS33590.1 - 3.7e-08 33.4 9.9 0.0011 19.0 1.6 6.0 6 1 1 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EPS33590.1 - 7.2e-08 32.6 16.4 0.00019 21.6 0.8 5.5 4 2 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 EPS33590.1 - 2.9e-07 30.1 30.7 0.00012 22.0 0.2 8.5 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 EPS33590.1 - 3.2e-07 30.3 4.7 1.7 9.2 0.1 7.0 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_7 PF13176.6 EPS33590.1 - 2e-05 24.3 4.5 4.2 7.6 0.1 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_4 PF07721.14 EPS33590.1 - 0.00072 19.9 1.7 0.4 11.4 0.1 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_3 PF07720.12 EPS33590.1 - 0.0064 16.5 0.1 0.34 10.9 0.1 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.17 EPS33590.1 - 0.022 15.2 0.1 0.022 15.2 0.1 3.1 3 0 0 3 3 2 0 Bacterial transcriptional activator domain TPR_6 PF13174.6 EPS33590.1 - 0.22 12.2 23.9 1.3 9.8 0.2 7.6 11 0 0 11 11 6 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 EPS33590.1 - 0.28 11.6 3.3 14 6.2 0.1 3.7 3 1 0 3 3 3 0 Alkyl sulfatase dimerisation TPR_10 PF13374.6 EPS33590.1 - 1.2 9.1 10.1 32 4.6 0.0 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat Tim54 PF11711.8 EPS33591.1 - 6.1e-151 502.5 0.1 7.1e-151 502.2 0.1 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Pkinase PF00069.25 EPS33592.1 - 1.9e-56 191.4 0.9 2.5e-55 187.7 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS33592.1 - 5.4e-25 88.1 0.3 1.9e-19 70.0 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EPS33592.1 - 4.2e-06 26.0 0.0 4.2e-06 26.0 0.0 1.7 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 EPS33592.1 - 0.00025 20.5 0.1 0.00068 19.0 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EPS33592.1 - 0.00046 19.6 0.3 0.0013 18.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 EPS33592.1 - 0.0079 15.3 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 EPS33592.1 - 0.011 15.6 0.1 0.011 15.6 0.1 3.1 2 2 1 3 3 2 0 Phosphotransferase enzyme family NFACT-C PF11923.8 EPS33592.1 - 0.05 13.5 0.2 0.05 13.5 0.2 1.8 2 0 0 2 2 2 0 NFACT protein C-terminal domain FTA2 PF13095.6 EPS33592.1 - 0.088 12.4 4.1 1.8 8.1 0.1 3.0 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EPS33592.1 - 0.14 10.9 0.0 0.14 10.9 0.0 1.8 3 0 0 3 3 3 0 Fungal protein kinase PA28_alpha PF02251.18 EPS33592.1 - 0.15 12.1 0.1 0.84 9.7 0.0 2.2 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit Spt20 PF12090.8 EPS33592.1 - 2.3 7.7 18.4 4.4 6.9 18.4 1.4 1 0 0 1 1 1 0 Spt20 family SF3A2 PF16835.5 EPS33593.1 - 8.6e-37 125.4 0.0 1.6e-36 124.5 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 EPS33593.1 - 3.5e-06 27.2 0.9 6.7e-06 26.3 0.9 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PRP4 PF08799.11 EPS33593.1 - 0.053 13.1 1.5 0.11 12.1 1.5 1.6 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like CAP_GLY PF01302.25 EPS33594.1 - 2e-19 69.4 0.2 3.4e-19 68.6 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 EPS33594.1 - 2.4e-15 56.4 6.6 0.0015 18.9 1.2 4.7 3 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EPS33594.1 - 1.3e-09 37.7 4.9 0.01 15.6 0.3 5.2 2 2 3 5 5 5 4 Leucine rich repeat LRR_9 PF14580.6 EPS33594.1 - 8.3e-08 31.9 0.0 0.0022 17.5 0.0 3.3 2 1 0 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 EPS33594.1 - 0.00062 19.6 6.8 5 7.4 0.0 5.4 6 0 0 6 6 6 2 Leucine Rich repeat DUF3352 PF11832.8 EPS33594.1 - 0.039 12.6 0.5 0.061 12.0 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3352) LRR_1 PF00560.33 EPS33594.1 - 1.1 10.1 5.7 37 5.4 0.1 4.8 4 2 1 5 5 5 0 Leucine Rich Repeat Zn_clus PF00172.18 EPS33596.1 - 2.3e-08 34.0 8.6 3.9e-08 33.3 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-U1 PF06220.12 EPS33597.1 - 9.8e-06 25.2 0.1 1.5e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 U1 zinc finger 2-Hacid_dh_C PF02826.19 EPS33598.1 - 1.6e-58 197.0 0.0 2e-58 196.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EPS33598.1 - 8.1e-15 54.7 0.0 1.1e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EPS33598.1 - 4.6e-05 23.6 0.2 7.1e-05 23.0 0.2 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 EPS33598.1 - 0.0057 16.2 0.0 0.0094 15.5 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 EPS33598.1 - 0.071 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain APH PF01636.23 EPS33599.1 - 0.1 12.5 0.8 0.17 11.8 0.8 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4187 PF13821.6 EPS33599.1 - 0.12 12.2 0.1 0.28 11.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) CwfJ_C_1 PF04677.15 EPS33600.1 - 3.7e-30 104.3 0.0 9.6e-30 103.0 0.0 1.7 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 EPS33600.1 - 1.3e-29 102.9 0.1 6e-29 100.8 0.1 2.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Dsh_C PF12316.8 EPS33600.1 - 2.4 8.5 16.8 1.4e+02 2.7 0.0 2.7 2 1 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal ATP_bind_1 PF03029.17 EPS33601.1 - 1e-71 241.6 0.0 1.4e-71 241.1 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 EPS33601.1 - 1.2e-05 24.9 0.0 0.0015 18.1 0.0 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 EPS33601.1 - 7.7e-05 21.8 0.0 0.023 13.7 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 EPS33601.1 - 0.0012 18.4 0.0 0.002 17.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region MMR_HSR1 PF01926.23 EPS33601.1 - 0.0013 18.8 0.0 0.021 14.9 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase PRK PF00485.18 EPS33601.1 - 0.0027 17.5 0.1 0.018 14.8 0.0 2.2 3 0 0 3 3 3 1 Phosphoribulokinase / Uridine kinase family FeoB_N PF02421.18 EPS33601.1 - 0.0041 16.6 0.0 0.12 11.9 0.0 2.5 3 0 0 3 3 3 1 Ferrous iron transport protein B NACHT PF05729.12 EPS33601.1 - 0.0056 16.6 0.0 0.015 15.2 0.0 1.7 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.6 EPS33601.1 - 0.0067 16.7 0.0 0.019 15.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EPS33601.1 - 0.0073 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EPS33601.1 - 0.008 15.4 0.0 0.017 14.3 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_24 PF13479.6 EPS33601.1 - 0.0092 15.7 0.0 0.023 14.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 EPS33601.1 - 0.012 15.3 0.0 0.086 12.5 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain G-alpha PF00503.20 EPS33601.1 - 0.016 14.4 0.0 0.48 9.5 0.0 2.3 2 0 0 2 2 2 0 G-protein alpha subunit AAA_33 PF13671.6 EPS33601.1 - 0.019 15.1 0.0 0.044 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 EPS33601.1 - 0.021 14.3 0.0 5 6.5 0.0 3.1 3 0 0 3 3 3 0 ADP-ribosylation factor family Roc PF08477.13 EPS33601.1 - 0.024 14.9 0.0 2.4 8.4 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 EPS33601.1 - 0.026 14.4 0.1 8.1 6.3 0.0 3.0 3 0 0 3 3 3 0 RsgA GTPase AAA_16 PF13191.6 EPS33601.1 - 0.026 14.9 0.0 0.052 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain cobW PF02492.19 EPS33601.1 - 0.031 13.9 0.0 2.1 7.9 0.0 2.3 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Methyltransf_32 PF13679.6 EPS33601.1 - 0.038 14.0 0.0 0.07 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain GST_N_3 PF13417.6 EPS33603.1 - 3.3e-21 75.5 0.1 7.3e-21 74.4 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EPS33603.1 - 7.4e-17 61.4 0.0 1.6e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EPS33603.1 - 2e-09 37.6 0.0 4.3e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EPS33603.1 - 4.9e-08 32.9 0.1 1.1e-07 31.8 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 EPS33603.1 - 4.4e-06 27.2 0.0 9.6e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EPS33603.1 - 0.00054 20.1 0.0 0.00097 19.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 EPS33603.1 - 0.0078 16.4 0.0 0.018 15.3 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_C PF00043.25 EPS33603.1 - 0.018 15.3 0.0 0.034 14.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SUZ PF12752.7 EPS33604.1 - 0.00033 21.4 7.8 0.00033 21.4 7.8 4.3 3 2 0 3 3 3 1 SUZ domain Fungal_trans PF04082.18 EPS33606.1 - 6.3e-20 71.3 0.0 1e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS33606.1 - 8.8e-05 22.6 4.9 8.8e-05 22.6 4.9 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short_C2 PF13561.6 EPS33607.1 - 7.8e-40 136.9 0.1 9.1e-40 136.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPS33607.1 - 1.7e-36 125.5 0.1 2e-36 125.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPS33607.1 - 8.3e-11 42.1 0.2 1.2e-10 41.6 0.2 1.2 1 0 0 1 1 1 1 KR domain Pantoate_transf PF02548.15 EPS33607.1 - 0.017 14.5 0.1 0.027 13.9 0.1 1.2 1 0 0 1 1 1 0 Ketopantoate hydroxymethyltransferase Aldo_ket_red PF00248.21 EPS33610.1 - 2.6e-53 181.1 0.0 7.3e-53 179.7 0.0 1.6 1 1 0 1 1 1 1 Aldo/keto reductase family Hydrolase_6 PF13344.6 EPS33611.1 - 3.2e-23 81.7 0.0 5.4e-23 81.0 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EPS33611.1 - 1.9e-20 72.7 0.0 4.1e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EPS33611.1 - 0.0046 17.3 0.0 0.65 10.2 0.0 3.0 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EPS33611.1 - 0.019 15.0 0.0 0.43 10.6 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 EPS33611.1 - 0.063 12.9 0.1 0.14 11.7 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Apt1 PF10351.9 EPS33611.1 - 0.13 11.1 0.3 0.22 10.3 0.0 1.4 2 0 0 2 2 2 0 Golgi-body localisation protein domain LRR_6 PF13516.6 EPS33614.1 - 0.00017 21.4 4.1 0.35 11.0 0.2 5.1 4 0 0 4 4 4 2 Leucine Rich repeat LRR_4 PF12799.7 EPS33614.1 - 0.0084 16.5 15.5 0.16 12.4 1.2 5.8 3 1 4 7 7 7 3 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EPS33614.1 - 0.012 15.5 0.1 0.031 14.2 0.1 1.8 1 0 0 1 1 1 0 F-box-like LRR_8 PF13855.6 EPS33614.1 - 0.058 13.2 6.5 7 6.5 1.0 4.2 3 2 0 3 3 3 0 Leucine rich repeat LRR_1 PF00560.33 EPS33614.1 - 1.4 9.8 6.6 2.4e+02 2.9 0.0 5.8 6 0 0 6 6 6 0 Leucine Rich Repeat BSD PF03909.17 EPS33615.1 - 1.3e-26 92.3 15.9 4.4e-14 52.2 0.2 3.6 5 0 0 5 5 5 2 BSD domain PH_TFIIH PF08567.11 EPS33615.1 - 5.4e-23 81.1 0.0 1.3e-22 79.9 0.0 1.7 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain PIN_8 PF18476.1 EPS33615.1 - 0.17 11.7 2.6 0.2 11.5 0.4 2.2 2 0 0 2 2 2 0 PIN like domain DUF1751 PF08551.10 EPS33616.1 - 0.017 15.7 0.1 0.033 14.7 0.1 1.5 1 0 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) PRCC PF10253.9 EPS33616.1 - 0.02 15.7 0.0 0.022 15.6 0.0 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting ING PF12998.7 EPS33617.1 - 3.1e-11 43.8 0.0 6.6e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EPS33617.1 - 1.2e-06 28.3 8.7 2.1e-06 27.5 8.7 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 EPS33617.1 - 0.0056 16.9 1.2 0.013 15.8 1.2 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain PHD_2 PF13831.6 EPS33617.1 - 0.14 11.7 2.5 0.25 11.0 2.5 1.4 1 0 0 1 1 1 0 PHD-finger Prp19 PF08606.11 EPS33617.1 - 1.3 9.0 5.6 0.97 9.5 1.6 2.3 2 0 0 2 2 2 0 Prp19/Pso4-like Transket_pyr PF02779.24 EPS33618.1 - 2.3e-64 216.4 0.0 3.6e-64 215.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 EPS33618.1 - 9.8e-59 197.4 0.0 1.7e-58 196.7 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 EPS33618.1 - 1e-58 198.7 0.0 1.5e-58 198.1 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component 2-oxogl_dehyd_N PF16078.5 EPS33618.1 - 5.6e-20 70.7 0.7 5.6e-20 70.7 0.7 2.2 2 0 0 2 2 2 1 2-oxoglutarate dehydrogenase N-terminus baeRF_family12 PF18856.1 EPS33618.1 - 0.17 12.5 0.1 0.69 10.5 0.0 2.0 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 12 DUF4449 PF14613.6 EPS33620.1 - 1.2e-62 210.8 1.7 1.2e-62 210.8 1.7 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Rox3 PF08633.10 EPS33624.1 - 8.1e-61 205.9 0.0 1.7e-60 204.8 0.0 1.5 1 0 0 1 1 1 1 Rox3 mediator complex subunit PBP1_TM PF14812.6 EPS33624.1 - 0.1 13.0 0.4 0.29 11.5 0.4 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Fungal_trans PF04082.18 EPS33625.1 - 1.3e-15 57.2 0.2 2.4e-15 56.3 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS33625.1 - 2.1e-09 37.3 11.3 3.7e-09 36.6 11.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ZnuA PF01297.17 EPS33625.1 - 0.061 12.7 0.3 0.1 12.0 0.3 1.2 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic Fungal_trans PF04082.18 EPS33627.1 - 7.7e-25 87.4 0.3 1.1e-24 86.9 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS33627.1 - 2.1e-08 34.2 7.5 3.9e-08 33.3 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PXB PF12828.7 EPS33627.1 - 0.056 13.4 0.4 0.12 12.4 0.4 1.5 1 0 0 1 1 1 0 PX-associated DUF4202 PF13875.6 EPS33628.1 - 1.8e-75 253.0 0.1 2e-75 252.8 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) Unstab_antitox PF09720.10 EPS33628.1 - 3.3 7.8 5.3 10 6.2 1.8 2.6 2 0 0 2 2 2 0 Putative addiction module component VIT1 PF01988.19 EPS33629.1 - 4.7e-65 219.5 3.7 5.5e-65 219.2 3.7 1.0 1 0 0 1 1 1 1 VIT family CsgG PF03783.14 EPS33629.1 - 0.19 11.0 0.2 0.3 10.3 0.2 1.2 1 0 0 1 1 1 0 Curli production assembly/transport component CsgG GCFC PF07842.12 EPS33631.1 - 1.6e-83 280.6 2.7 2.5e-83 279.9 2.7 1.3 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.23 EPS33631.1 - 3.7e-18 65.1 2.5 7.3e-18 64.2 2.5 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EPS33631.1 - 7e-09 35.6 1.4 2.1e-08 34.1 1.4 1.8 1 0 0 1 1 1 1 G-patch domain RhgB_N PF09284.10 EPS33631.1 - 0.18 11.3 0.1 0.3 10.6 0.1 1.2 1 0 0 1 1 1 0 Rhamnogalacturonan lyase B, N-terminal Sod_Fe_C PF02777.18 EPS33632.1 - 3.2e-38 130.0 2.2 3.4e-38 129.9 0.5 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EPS33632.1 - 1.8e-30 105.2 2.2 3.1e-30 104.5 2.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain F-box PF00646.33 EPS33633.1 - 0.0031 17.3 0.7 0.0065 16.3 0.0 2.0 2 0 0 2 2 2 1 F-box domain Cnn_1N PF07989.11 EPS33634.1 - 1.5e-05 25.0 20.4 5.5e-05 23.3 15.9 3.0 2 1 0 2 2 2 1 Centrosomin N-terminal motif 1 Rota_NSP4 PF01452.16 EPS33634.1 - 2.8 7.6 4.2 4.6 6.9 4.2 1.2 1 0 0 1 1 1 0 Rotavirus non structural protein Fzo_mitofusin PF04799.13 EPS33634.1 - 4.9 6.7 5.2 12 5.4 5.2 1.6 1 0 0 1 1 1 0 fzo-like conserved region Sld5 PF05916.11 EPS33635.1 - 1.7e-19 70.2 0.0 2.2e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein Metallophos PF00149.28 EPS33636.1 - 2.3e-13 51.1 0.1 3.5e-13 50.5 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase His_Phos_2 PF00328.22 EPS33637.1 - 4.6e-18 65.7 0.0 4.3e-15 56.0 0.0 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) AIRC PF00731.20 EPS33640.1 - 2e-57 193.0 4.1 4.1e-57 191.9 4.1 1.6 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 EPS33640.1 - 2.3e-51 173.8 0.0 4.6e-51 172.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 EPS33640.1 - 4.9e-18 64.6 0.5 1.4e-17 63.1 0.2 2.0 2 0 0 2 2 2 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 EPS33640.1 - 1.2e-06 28.2 0.1 2.3e-05 24.0 0.1 2.7 2 1 0 2 2 2 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 EPS33640.1 - 3e-06 26.9 0.8 4.7e-06 26.2 0.1 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_5 PF13549.6 EPS33640.1 - 0.0062 16.0 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain PrpR_N PF06506.11 EPS33640.1 - 0.0083 15.7 0.8 0.031 13.8 0.1 2.3 3 0 0 3 3 3 1 Propionate catabolism activator AlaDh_PNT_C PF01262.21 EPS33640.1 - 0.011 15.0 0.0 0.028 13.7 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ATP-grasp_3 PF02655.14 EPS33640.1 - 0.026 14.6 0.0 0.056 13.5 0.0 1.7 1 1 0 1 1 1 0 ATP-grasp domain PPP4R2 PF09184.11 EPS33641.1 - 3.1e-08 33.6 1.0 3.3e-07 30.2 0.7 2.1 1 1 0 1 1 1 1 PPP4R2 Abhydrolase_1 PF00561.20 EPS33643.1 - 6.1e-30 104.7 0.1 8.7e-30 104.2 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EPS33643.1 - 2.1e-11 43.6 0.0 8.1e-09 35.1 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EPS33643.1 - 5.5e-09 36.9 1.2 7.6e-09 36.5 1.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 EPS33643.1 - 0.028 14.5 0.0 0.066 13.3 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein Peptidase_S28 PF05577.12 EPS33643.1 - 0.088 11.6 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 RNA_ligase PF09414.10 EPS33643.1 - 0.11 12.8 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 RNA ligase E1-E2_ATPase PF00122.20 EPS33644.1 - 3.8e-50 169.9 0.6 1.1e-49 168.4 0.6 1.8 1 0 0 1 1 1 1 E1-E2 ATPase HMA PF00403.26 EPS33644.1 - 8e-48 160.7 1.4 6.1e-12 45.8 0.0 4.5 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.26 EPS33644.1 - 3.2e-36 125.6 0.1 7e-36 124.5 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EPS33644.1 - 3.3e-06 27.0 0.4 7.6e-05 22.6 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Ion_trans PF00520.31 EPS33644.1 - 0.013 14.8 0.4 0.082 12.1 0.0 2.0 2 0 0 2 2 2 0 Ion transport protein CSN7a_helixI PF18392.1 EPS33645.1 - 0.00093 19.1 0.1 0.0017 18.2 0.1 1.3 1 0 0 1 1 1 1 COP9 signalosome complex subunit 7a helix I domain PCI PF01399.27 EPS33645.1 - 0.0024 18.3 0.0 0.0051 17.3 0.0 1.5 1 0 0 1 1 1 1 PCI domain DUF1192 PF06698.11 EPS33645.1 - 0.051 13.6 0.3 0.13 12.3 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) RGS PF00615.19 EPS33646.1 - 5.6e-12 46.0 0.0 2.4e-08 34.3 0.0 2.4 2 0 0 2 2 2 2 Regulator of G protein signaling domain Bromodomain PF00439.25 EPS33647.1 - 4.5e-24 84.3 1.2 8.8e-24 83.4 1.2 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 EPS33647.1 - 2.5e-08 34.2 0.0 4.7e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EPS33647.1 - 6.3e-07 29.4 0.2 3.3e-06 27.1 0.1 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EPS33647.1 - 0.00023 21.5 0.2 0.00051 20.4 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Rad1 PF02144.16 EPS33648.1 - 7.6e-92 307.3 0.0 9.2e-92 307.0 0.0 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 AAA_23 PF13476.6 EPS33649.1 - 7.1e-35 121.3 2.8 7.1e-35 121.3 2.8 7.3 3 2 2 5 5 5 1 AAA domain SMC_N PF02463.19 EPS33649.1 - 1.1e-14 54.4 5.6 1.2e-09 38.0 2.7 3.8 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EPS33649.1 - 1.9e-06 28.0 0.0 5.6e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 EPS33649.1 - 6.4e-06 26.2 18.5 0.0013 18.6 0.0 4.0 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EPS33649.1 - 3e-05 23.9 3.0 3e-05 23.9 3.0 5.6 1 1 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 EPS33649.1 - 0.00076 19.2 0.0 0.0017 18.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain KNOX2 PF03791.13 EPS33649.1 - 0.018 14.5 0.1 0.99 9.0 0.1 3.4 2 0 0 2 2 2 0 KNOX2 domain DUF3018 PF11455.8 EPS33649.1 - 0.036 14.0 0.3 0.036 14.0 0.3 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3018) AAA_16 PF13191.6 EPS33649.1 - 0.062 13.7 0.0 0.062 13.7 0.0 5.5 5 2 0 5 5 5 0 AAA ATPase domain ABC_tran PF00005.27 EPS33649.1 - 0.11 13.0 0.0 0.11 13.0 0.0 7.2 3 2 0 3 3 3 0 ABC transporter GATA PF00320.27 EPS33650.1 - 3e-15 55.5 5.6 5.5e-15 54.7 5.6 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.25 EPS33650.1 - 6.1e-09 35.9 0.1 3.2e-08 33.6 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_3 PF08447.12 EPS33650.1 - 1.7e-08 34.7 0.0 2.9e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.10 EPS33650.1 - 6.5e-07 29.6 0.0 1.3e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 EPS33650.1 - 0.00017 21.8 0.0 0.00045 20.4 0.0 1.7 1 0 0 1 1 1 1 PAS domain Nudix_N_2 PF14803.6 EPS33650.1 - 8.5 6.4 7.0 3.2 7.7 1.9 2.5 1 1 2 3 3 3 0 Nudix N-terminal NAD_binding_6 PF08030.12 EPS33652.1 - 1.3e-06 28.6 0.0 4.4e-05 23.7 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 EPS33652.1 - 4.4e-06 27.3 0.1 0.014 16.0 0.0 3.0 3 0 0 3 3 3 2 Oxidoreductase NAD-binding domain Metallophos PF00149.28 EPS33653.1 - 9e-18 65.5 1.4 1.5e-17 64.7 0.3 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EPS33653.1 - 0.00043 20.5 0.0 0.0069 16.6 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain HAD PF12710.7 EPS33654.1 - 2e-20 74.0 0.0 2.5e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.12 EPS33654.1 - 0.015 14.9 0.0 0.033 13.7 0.0 1.6 1 1 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) GCD14 PF08704.10 EPS33655.1 - 1.6e-07 31.2 0.0 0.00047 19.9 0.0 2.3 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit GCD14_N PF14801.6 EPS33655.1 - 0.0012 18.6 0.2 0.0023 17.7 0.2 1.4 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_25 PF13649.6 EPS33655.1 - 0.0014 19.3 0.0 0.79 10.5 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Hydrolase_4 PF12146.8 EPS33656.1 - 2.7e-47 161.0 0.0 3.3e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EPS33656.1 - 2.4e-12 47.9 0.5 3.1e-12 47.6 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EPS33656.1 - 1e-09 38.4 0.2 1.3e-07 31.5 0.2 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 EPS33656.1 - 0.034 13.0 0.0 0.055 12.4 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme DUF1749 PF08538.10 EPS33656.1 - 0.072 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) LRR_8 PF13855.6 EPS33657.1 - 7.9e-16 57.6 15.9 3e-10 39.7 3.6 2.1 1 1 2 3 3 3 3 Leucine rich repeat Exo_endo_phos PF03372.23 EPS33657.1 - 2.1e-15 56.9 0.5 3.4e-15 56.2 0.1 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 EPS33657.1 - 1.8e-14 53.6 4.3 3.4e-08 33.7 0.7 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EPS33657.1 - 1.4e-05 24.9 3.5 1.7 9.5 0.0 4.9 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.6 EPS33657.1 - 0.056 13.5 9.4 0.56 10.4 0.2 4.6 5 0 0 5 5 5 0 Leucine Rich repeat Methyltransf_25 PF13649.6 EPS33658.1 - 1.4e-12 48.2 0.0 2.3e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS33658.1 - 1.7e-08 35.0 0.0 2.9e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPS33658.1 - 4.7e-05 23.2 0.0 7.9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPS33658.1 - 8.4e-05 22.5 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPS33658.1 - 0.00012 21.5 0.0 0.00018 20.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EPS33658.1 - 0.0065 17.2 0.0 0.013 16.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF5348 PF17295.2 EPS33658.1 - 0.082 12.8 0.4 0.65 10.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5348) Complex1_LYR PF05347.15 EPS33659.1 - 7.9e-06 25.8 0.5 1.3e-05 25.2 0.5 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EPS33659.1 - 0.00017 22.2 1.6 0.00023 21.8 1.6 1.2 1 0 0 1 1 1 1 Complex1_LYR-like 4HBT_2 PF13279.6 EPS33660.1 - 1.1e-32 113.1 0.1 1.5e-32 112.6 0.1 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.22 EPS33660.1 - 5.6e-06 26.6 0.0 9.8e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.17 EPS33660.1 - 0.01 15.1 0.2 0.059 12.6 0.0 2.2 2 1 0 2 2 2 0 Acyl-ACP thioesterase Fib_alpha PF08702.10 EPS33660.1 - 0.18 12.0 0.3 0.27 11.4 0.3 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family MmgE_PrpD PF03972.14 EPS33661.1 - 2.1e-136 455.0 2.2 2.3e-136 454.8 2.2 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Serglycin PF04360.12 EPS33662.1 - 1.1 9.2 6.7 3.4 7.6 6.7 1.8 1 0 0 1 1 1 0 Serglycin Flavin_Reduct PF01613.18 EPS33663.1 - 3.1e-28 98.8 0.2 5.2e-28 98.0 0.2 1.4 1 0 0 1 1 1 1 Flavin reductase like domain DUF4505 PF14956.6 EPS33663.1 - 0.066 13.0 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4505) DUF3235 PF11574.8 EPS33664.1 - 5.5 7.9 11.0 0.51 11.2 5.7 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3235) Vps5 PF09325.10 EPS33665.1 - 4.7e-89 298.0 3.5 4.7e-89 298.0 3.5 1.4 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.24 EPS33665.1 - 3.7e-24 84.9 0.1 8.4e-24 83.7 0.0 1.7 2 0 0 2 2 2 1 PX domain BAR_3 PF16746.5 EPS33665.1 - 0.00058 19.6 8.0 0.008 15.9 2.9 2.5 1 1 1 2 2 2 2 BAR domain of APPL family BAR_2 PF10455.9 EPS33665.1 - 0.08 12.1 1.6 0.13 11.4 1.6 1.3 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF3450 PF11932.8 EPS33665.1 - 0.64 9.3 9.0 0.18 11.1 5.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Aldolase_II PF00596.21 EPS33666.1 - 1.7e-43 148.7 0.0 2e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Calreticulin PF00262.18 EPS33667.1 - 1.3e-171 570.5 15.2 1.6e-171 570.2 15.2 1.1 1 0 0 1 1 1 1 Calreticulin family Aldedh PF00171.22 EPS33668.1 - 1.5e-137 458.9 0.3 1.8e-137 458.7 0.3 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Dynamitin PF04912.14 EPS33670.1 - 3.3e-71 240.7 6.3 3.7e-35 122.0 1.1 2.2 2 0 0 2 2 2 2 Dynamitin Jnk-SapK_ap_N PF09744.9 EPS33670.1 - 0.0002 21.6 10.3 0.011 15.9 0.5 2.9 3 0 0 3 3 3 2 JNK_SAPK-associated protein-1 SlyX PF04102.12 EPS33670.1 - 0.028 15.0 3.2 3 8.5 0.2 3.8 3 0 0 3 3 3 0 SlyX CCDC32 PF14989.6 EPS33670.1 - 0.084 12.9 0.8 0.19 11.7 0.2 1.8 2 0 0 2 2 2 0 Coiled-coil domain containing 32 DUF1664 PF07889.12 EPS33670.1 - 0.1 12.6 0.1 0.58 10.2 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) CLZ PF16526.5 EPS33670.1 - 0.15 12.4 10.5 15 6.1 1.1 5.7 5 1 1 6 6 6 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Spc24 PF08286.11 EPS33670.1 - 0.16 12.3 3.3 7.8 6.8 0.2 3.2 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 LPP PF04728.13 EPS33670.1 - 0.25 11.8 4.4 0.4 11.1 1.0 3.1 4 0 0 4 4 3 0 Lipoprotein leucine-zipper Spc7 PF08317.11 EPS33670.1 - 0.28 10.0 2.9 0.8 8.5 0.1 2.6 3 0 0 3 3 3 0 Spc7 kinetochore protein Prefoldin_2 PF01920.20 EPS33670.1 - 0.57 10.2 5.2 2.3 8.2 0.7 3.1 4 0 0 4 4 3 0 Prefoldin subunit Laminin_II PF06009.12 EPS33670.1 - 0.59 10.1 4.5 1.9 8.5 0.0 3.2 3 0 0 3 3 3 0 Laminin Domain II DUF2203 PF09969.9 EPS33670.1 - 0.79 10.5 4.0 6 7.6 0.1 3.3 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) MbeD_MobD PF04899.12 EPS33670.1 - 1.4 9.1 4.8 9.2 6.5 0.5 3.5 4 0 0 4 4 4 0 MbeD/MobD like ZapB PF06005.12 EPS33670.1 - 1.8 9.1 5.7 15 6.1 0.9 3.4 3 0 0 3 3 3 0 Cell division protein ZapB Snapin_Pallidin PF14712.6 EPS33670.1 - 1.9 8.9 5.6 6.3 7.3 0.4 3.7 4 1 0 4 4 4 0 Snapin/Pallidin DivIC PF04977.15 EPS33670.1 - 3.8 7.4 14.9 0.42 10.4 0.2 3.8 3 1 1 4 4 4 0 Septum formation initiator DASH_Spc19 PF08287.11 EPS33670.1 - 9 6.2 10.8 13 5.6 1.2 3.5 3 1 1 4 4 4 0 Spc19 Pkinase PF00069.25 EPS33672.1 - 1.6e-70 237.5 0.0 2.2e-70 237.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS33672.1 - 4.2e-35 121.3 0.0 7.4e-35 120.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EPS33672.1 - 3.2e-06 26.7 0.0 4.7e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EPS33672.1 - 0.00035 19.5 0.1 0.0009 18.1 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EPS33672.1 - 0.0026 17.1 0.0 0.005 16.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 EPS33672.1 - 0.034 13.7 0.0 0.24 10.9 0.0 2.3 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL TetR_C_27 PF17935.1 EPS33672.1 - 0.1 12.7 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain HD_4 PF13328.6 EPS33673.1 - 0.1 12.4 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 HD domain Pkinase PF00069.25 EPS33674.1 - 4.7e-57 193.4 0.0 6.1e-57 193.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS33674.1 - 4.9e-42 144.0 0.0 6.9e-42 143.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EPS33674.1 - 7.3e-05 22.2 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EPS33674.1 - 0.001 17.9 0.0 0.0023 16.8 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EPS33674.1 - 0.0025 17.8 0.1 0.041 13.8 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family FTA2 PF13095.6 EPS33674.1 - 0.021 14.4 0.0 0.051 13.2 0.0 1.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EPS33674.1 - 0.024 14.0 0.2 0.054 12.8 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EPS33674.1 - 0.084 12.5 0.1 0.28 10.8 0.1 1.8 1 1 0 1 1 1 0 RIO1 family Aminotran_1_2 PF00155.21 EPS33676.1 - 3.5e-18 65.9 0.0 4.5e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EPS33676.1 - 0.0013 18.2 0.0 0.008 15.5 0.0 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_MocR PF12897.7 EPS33676.1 - 0.0031 16.4 0.0 0.0088 14.9 0.0 1.6 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase TPP_enzyme_N PF02776.18 EPS33677.1 - 2.5e-41 141.2 0.1 8.9e-41 139.4 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EPS33677.1 - 9.3e-21 74.2 0.0 1.7e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EPS33677.1 - 5.3e-14 52.1 0.0 3.5e-13 49.5 0.0 2.3 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain BCDHK_Adom3 PF10436.9 EPS33678.1 - 4e-45 153.6 0.0 5.5e-45 153.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EPS33678.1 - 1.2e-11 45.1 0.0 2.4e-11 44.1 0.0 1.5 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Inhibitor_I9 PF05922.16 EPS33679.1 - 6e-06 26.8 0.2 8.5e-06 26.4 0.2 1.3 1 1 0 1 1 1 1 Peptidase inhibitor I9 DUF1989 PF09347.10 EPS33680.1 - 1.4e-60 203.7 0.0 2.4e-60 202.9 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1989) RNA_pol_Rpb2_3 PF04565.16 EPS33680.1 - 0.042 14.0 0.2 0.15 12.2 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 3 RIBIOP_C PF04950.12 EPS33681.1 - 6.3e-96 321.2 0.0 6.3e-96 321.2 0.0 1.7 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EPS33681.1 - 6.7e-28 96.6 0.0 1.9e-27 95.2 0.0 1.9 1 0 0 1 1 1 1 AARP2CN (NUC121) domain AAA_22 PF13401.6 EPS33681.1 - 2.1e-05 24.8 0.2 6.7e-05 23.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain ABC_tran PF00005.27 EPS33681.1 - 5.2e-05 23.8 1.5 0.00012 22.6 0.0 2.2 2 0 0 2 2 2 1 ABC transporter GTP_EFTU PF00009.27 EPS33681.1 - 6.8e-05 22.5 0.0 0.01 15.4 0.0 2.5 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EPS33681.1 - 0.00011 22.7 0.0 0.00037 20.9 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 EPS33681.1 - 0.00047 20.3 1.9 0.00049 20.3 0.0 2.1 2 0 0 2 2 1 1 AAA domain RsgA_GTPase PF03193.16 EPS33681.1 - 0.00096 19.1 0.0 0.0022 17.9 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase NACHT PF05729.12 EPS33681.1 - 0.0014 18.5 0.1 0.0033 17.4 0.1 1.6 1 1 0 1 1 1 1 NACHT domain PduV-EutP PF10662.9 EPS33681.1 - 0.002 17.9 0.1 0.016 14.9 0.1 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 EPS33681.1 - 0.0024 17.9 0.1 0.0075 16.3 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.14 EPS33681.1 - 0.0048 16.8 0.2 0.019 14.9 0.1 2.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ATPase_2 PF01637.18 EPS33681.1 - 0.0087 16.0 1.6 0.012 15.5 0.0 1.9 2 0 0 2 2 1 1 ATPase domain predominantly from Archaea AAA PF00004.29 EPS33681.1 - 0.0093 16.4 0.0 0.022 15.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EPS33681.1 - 0.01 16.1 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EPS33681.1 - 0.014 15.4 0.0 0.041 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EPS33681.1 - 0.017 14.3 0.0 0.035 13.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 EPS33681.1 - 0.021 15.2 0.0 0.056 13.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Roc PF08477.13 EPS33681.1 - 0.022 15.0 0.0 0.051 13.8 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 EPS33681.1 - 0.029 14.1 0.1 0.088 12.5 0.1 1.8 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EPS33681.1 - 0.033 14.2 0.0 0.092 12.7 0.0 1.7 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 EPS33681.1 - 0.033 13.7 0.0 0.078 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region SRP54 PF00448.22 EPS33681.1 - 0.044 13.4 0.1 0.09 12.4 0.1 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain SRPRB PF09439.10 EPS33681.1 - 0.047 13.1 0.0 0.097 12.1 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit cobW PF02492.19 EPS33681.1 - 0.061 12.9 0.3 0.11 12.0 0.3 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain KAP_NTPase PF07693.14 EPS33681.1 - 0.11 11.7 0.0 0.24 10.6 0.0 1.5 1 0 0 1 1 1 0 KAP family P-loop domain AAA_21 PF13304.6 EPS33681.1 - 0.11 12.3 0.0 0.11 12.3 0.0 2.8 2 1 0 2 2 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 EPS33681.1 - 0.12 12.4 0.3 0.5 10.4 0.1 2.2 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 EPS33681.1 - 0.15 11.9 0.1 0.47 10.4 0.0 1.8 2 0 0 2 2 1 0 Rad17 P-loop domain Pox_A32 PF04665.12 EPS33681.1 - 0.18 11.2 0.0 0.35 10.3 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_29 PF13555.6 EPS33681.1 - 0.19 11.5 0.0 0.43 10.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 EPS33681.1 - 0.4 11.2 0.0 0.4 11.2 0.0 3.7 3 1 0 3 3 2 0 AAA domain AAA_18 PF13238.6 EPS33681.1 - 0.46 11.0 6.3 0.25 11.9 0.1 3.5 3 0 0 3 3 3 0 AAA domain MFS_1 PF07690.16 EPS33683.1 - 1.2e-40 139.5 32.7 1.2e-40 139.5 32.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EPS33683.1 - 6.6e-10 38.0 2.6 1.2e-09 37.2 2.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EPS33683.1 - 0.0012 17.9 27.9 0.0054 15.7 27.9 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter Fungal_trans PF04082.18 EPS33684.1 - 1.6e-17 63.4 0.2 2.7e-17 62.7 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.6 EPS33684.1 - 2.3e-07 30.9 11.8 4.7e-07 29.9 2.6 2.9 3 0 0 3 3 3 2 Zinc-finger double domain DUF3499 PF12005.8 EPS33684.1 - 0.013 16.1 0.0 0.025 15.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3499) zf-C2H2 PF00096.26 EPS33684.1 - 0.78 10.3 19.1 0.094 13.2 3.6 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2HE PF16278.5 EPS33684.1 - 3.6 8.1 5.2 27 5.3 0.9 3.1 2 1 1 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger Glyoxalase PF00903.25 EPS33685.1 - 4.3e-13 49.6 0.0 2.2e-12 47.3 0.0 2.1 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EPS33685.1 - 2.3e-05 24.6 0.0 4.6e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EPS33685.1 - 0.00099 19.9 0.0 0.0034 18.2 0.0 2.0 1 1 0 1 1 1 1 Glyoxalase-like domain PaaX PF07848.12 EPS33685.1 - 0.016 15.4 0.0 0.051 13.8 0.0 1.7 2 0 0 2 2 2 0 PaaX-like protein PWI PF01480.17 EPS33686.1 - 2.1e-11 44.0 1.4 3.5e-11 43.2 0.3 1.9 2 0 0 2 2 2 1 PWI domain Nup35_RRM_2 PF14605.6 EPS33686.1 - 3.6e-08 33.3 0.0 1.3e-05 25.0 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 EPS33686.1 - 8.3e-08 31.9 2.3 4.8e-06 26.3 0.0 3.4 4 0 0 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EPS33686.1 - 0.0046 16.8 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 Occluded RNA-recognition motif zf-CCCH PF00642.24 EPS33686.1 - 0.0072 16.2 1.8 0.013 15.4 1.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_3 PF08777.11 EPS33686.1 - 0.018 15.1 3.0 0.064 13.3 0.0 2.7 3 0 0 3 3 3 0 RNA binding motif PHM7_cyt PF14703.6 EPS33686.1 - 0.12 12.6 4.4 0.23 11.7 0.0 2.9 3 1 1 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter GTP_EFTU PF00009.27 EPS33687.1 - 2.8e-64 216.2 0.1 3.8e-64 215.8 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EPS33687.1 - 4.1e-33 113.7 0.0 1.5e-32 111.9 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 EPS33687.1 - 2e-22 79.0 0.0 5.8e-22 77.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EPS33687.1 - 3.3e-13 49.8 0.0 1.5e-12 47.7 0.0 2.2 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EPS33687.1 - 2.2e-11 43.7 0.0 8e-11 41.9 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EPS33687.1 - 0.0018 18.3 0.0 0.0036 17.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase CTV_P23 PF04808.12 EPS33688.1 - 0.079 12.5 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Citrus tristeza virus (CTV) P23 protein AAA_lid_7 PF17867.1 EPS33688.1 - 0.1 12.8 0.4 0.73 10.1 0.0 2.4 2 0 0 2 2 2 0 Midasin AAA lid domain Solute_trans_a PF03619.16 EPS33689.1 - 8.3e-98 327.1 8.1 1.1e-97 326.7 8.1 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha CTK3_C PF12350.8 EPS33689.1 - 3.4 7.9 6.8 0.7 10.1 3.0 1.8 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 C-terminus Dynactin PF12455.8 EPS33691.1 - 2.2e-97 325.8 10.8 2.2e-97 325.8 10.8 4.8 4 1 2 6 6 6 1 Dynein associated protein CAP_GLY PF01302.25 EPS33691.1 - 1.5e-22 79.4 0.3 2.7e-22 78.6 0.3 1.4 1 0 0 1 1 1 1 CAP-Gly domain MAD PF05557.13 EPS33691.1 - 0.00063 18.2 7.2 0.00063 18.2 7.2 5.7 3 1 3 6 6 6 4 Mitotic checkpoint protein DUF2353 PF09789.9 EPS33691.1 - 0.0021 17.5 26.3 0.0021 17.5 26.3 4.6 2 2 3 5 5 5 1 Uncharacterized coiled-coil protein (DUF2353) HAD_2 PF13419.6 EPS33692.1 - 1.5e-07 31.7 0.0 2e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EPS33692.1 - 3.2e-07 30.9 0.0 9.1e-07 29.4 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EPS33692.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like Gasdermin PF04598.12 EPS33693.1 - 0.23 10.8 0.2 0.4 10.1 0.2 1.3 1 0 0 1 1 1 0 Gasdermin pore forming domain KH_1 PF00013.29 EPS33695.1 - 1.6e-31 107.9 5.7 1e-07 31.7 0.0 7.5 8 0 0 8 8 8 5 KH domain Glyco_hydro_2_N PF02837.18 EPS33697.1 - 3.2e-13 50.0 0.0 7.3e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.17 EPS33697.1 - 4.8e-12 45.6 0.1 8.4e-11 41.5 0.1 2.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.21 EPS33697.1 - 2.7e-06 28.0 0.0 9.8e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.6 EPS33697.1 - 0.043 14.4 0.0 0.13 12.9 0.0 1.8 2 0 0 2 2 2 0 Beta-galactosidase jelly roll domain p450 PF00067.22 EPS33698.1 - 1.2e-76 258.3 0.0 1.5e-76 258.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Chitin_synth_2 PF03142.15 EPS33699.1 - 1e-229 763.6 0.0 1.8e-229 762.7 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase DEK_C PF08766.11 EPS33699.1 - 4.9e-16 58.4 0.5 1.5e-15 56.8 0.5 1.8 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 EPS33699.1 - 6.2e-14 51.9 0.8 6.7e-08 32.6 0.0 3.1 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.6 EPS33699.1 - 7e-14 52.2 2.7 7e-14 52.2 2.7 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 EPS33699.1 - 2.7e-12 47.1 0.0 1.2e-11 45.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Myosin_head PF00063.21 EPS33699.1 - 1.4e-08 33.4 0.0 3.5e-08 32.2 0.0 1.5 1 1 0 1 1 1 1 Myosin head (motor domain) Glyco_transf_21 PF13506.6 EPS33699.1 - 4.3e-05 23.1 0.0 0.012 15.1 0.0 3.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 EPS33699.1 - 0.0019 18.0 0.0 0.17 11.6 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Chitin_synth_2 PF03142.15 EPS33700.1 - 3.2e-245 814.7 2.6 4.4e-245 814.3 2.6 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.21 EPS33700.1 - 7.8e-75 252.4 0.0 1.1e-73 248.7 0.0 2.0 1 1 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.11 EPS33700.1 - 5.3e-17 61.5 0.0 5.6e-16 58.2 0.1 2.4 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.28 EPS33700.1 - 6.3e-17 61.5 0.2 1.7e-13 50.5 0.1 3.2 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.6 EPS33700.1 - 2.8e-09 37.2 0.0 1.6e-08 34.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EPS33700.1 - 4.4e-09 36.5 6.2 4.4e-09 36.5 6.2 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 EPS33700.1 - 0.001 18.9 0.0 0.23 11.2 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 AAA_16 PF13191.6 EPS33700.1 - 0.04 14.3 0.1 0.12 12.8 0.1 1.8 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 EPS33700.1 - 0.14 12.1 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase PduV-EutP PF10662.9 EPS33700.1 - 0.15 11.8 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation GCN5L1 PF06320.13 EPS33701.1 - 7.4e-19 68.0 0.7 1.1e-18 67.5 0.7 1.2 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) MutL_C PF08676.11 EPS33702.1 - 4.2e-25 88.2 0.0 8.6e-25 87.2 0.0 1.5 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 EPS33702.1 - 1.1e-18 67.1 0.0 1.9e-17 63.0 0.0 3.0 3 0 0 3 3 3 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 EPS33702.1 - 4.4e-11 42.7 0.0 1.2e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EPS33702.1 - 2e-06 28.3 0.0 1.4e-05 25.5 0.0 2.5 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Serinc PF03348.15 EPS33703.1 - 6.2e-162 539.4 11.9 7e-162 539.2 11.9 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF21 PF01595.20 EPS33703.1 - 0.037 13.7 0.7 0.037 13.7 0.7 3.7 2 1 1 4 4 4 0 Cyclin M transmembrane N-terminal domain DUF4148 PF13663.6 EPS33703.1 - 1.8 8.8 6.6 0.38 11.0 0.8 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4148) Nodulin-like PF06813.13 EPS33704.1 - 7.9e-20 71.4 1.8 2e-19 70.1 1.8 1.7 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.16 EPS33704.1 - 7.3e-12 44.9 38.6 7.4e-10 38.3 19.5 2.8 1 1 1 3 3 3 2 Major Facilitator Superfamily GATA PF00320.27 EPS33705.1 - 6.7e-16 57.6 2.6 1.1e-15 56.9 2.6 1.4 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 EPS33705.1 - 0.009 15.5 0.5 0.017 14.6 0.5 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding DUF4618 PF15397.6 EPS33705.1 - 0.077 12.4 2.3 0.11 11.9 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Zn-ribbon_8 PF09723.10 EPS33705.1 - 0.096 12.8 0.2 0.21 11.7 0.2 1.5 1 0 0 1 1 1 0 Zinc ribbon domain DUF2387 PF09526.10 EPS33705.1 - 0.11 12.7 0.2 1.2 9.3 0.0 2.4 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) zf-ribbon_3 PF13248.6 EPS33705.1 - 0.14 11.6 0.9 15 5.2 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Auto_anti-p27 PF06677.12 EPS33705.1 - 0.23 11.7 0.6 0.38 11.0 0.6 1.3 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Pox_A_type_inc PF04508.12 EPS33705.1 - 0.35 10.8 8.0 1.3 9.0 0.5 3.7 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat ArfGap PF01412.18 EPS33705.1 - 1 9.4 2.7 0.74 9.9 0.5 1.9 2 1 0 2 2 2 0 Putative GTPase activating protein for Arf DivIVA PF05103.13 EPS33705.1 - 1.6 8.8 5.7 25 4.9 5.7 2.1 1 1 0 1 1 1 0 DivIVA protein CLZ PF16526.5 EPS33705.1 - 1.7 9.0 10.9 1.9 8.9 5.1 2.3 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PI3_PI4_kinase PF00454.27 EPS33706.1 - 8.5e-45 153.5 0.0 1.2e-44 153.0 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase SNF2_N PF00176.23 EPS33707.1 - 1e-61 208.6 1.0 1.8e-61 207.8 1.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EPS33707.1 - 2.2e-10 40.8 0.0 1e-09 38.7 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EPS33707.1 - 1.7e-06 27.9 0.0 4.5e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ribosomal_S27e PF01667.17 EPS33707.1 - 0.3 10.8 5.1 0.75 9.5 5.1 1.6 1 0 0 1 1 1 0 Ribosomal protein S27 zf-C3HC4_3 PF13920.6 EPS33707.1 - 1.4 8.8 6.9 4.4 7.2 6.9 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EPS33707.1 - 1.4 8.8 4.8 3 7.8 4.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Antifungal_pept PF11410.8 EPS33708.1 - 0.73 9.8 0.1 0.73 9.8 0.1 2.4 2 0 0 2 2 2 0 Antifungal peptide Med21 PF11221.8 EPS33709.1 - 8.2e-56 188.3 7.7 2.9e-55 186.5 7.7 1.7 1 1 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.13 EPS33709.1 - 0.0072 16.4 2.0 0.077 13.1 2.3 2.3 1 1 1 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 EzrA PF06160.12 EPS33709.1 - 0.0079 14.4 1.3 0.011 14.0 1.3 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA LMP PF04778.12 EPS33709.1 - 0.037 13.9 0.1 0.05 13.5 0.1 1.2 1 0 0 1 1 1 0 LMP repeated region Dzip-like_N PF13815.6 EPS33709.1 - 0.057 13.4 2.3 0.096 12.7 2.3 1.4 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal SlyX PF04102.12 EPS33709.1 - 0.22 12.2 2.5 4.9 7.9 0.5 2.8 3 0 0 3 3 3 0 SlyX APG6_N PF17675.1 EPS33709.1 - 0.9 10.1 7.6 1.9 9.1 7.6 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF641 PF04859.12 EPS33709.1 - 1.1 9.6 4.9 1.2 9.4 3.5 1.5 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Prefoldin_2 PF01920.20 EPS33709.1 - 8.9 6.3 10.5 0.92 9.5 5.6 1.9 2 1 1 3 3 3 0 Prefoldin subunit DUF2034 PF10356.9 EPS33710.1 - 2e-41 141.5 0.0 1e-24 87.0 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 EPS33710.1 - 1.6e-08 34.6 0.0 2.8e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease Spc24 PF08286.11 EPS33711.1 - 9.5e-37 125.4 1.8 2.2e-35 121.1 0.1 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 CLZ PF16526.5 EPS33711.1 - 0.0024 18.2 8.3 0.16 12.3 1.8 2.8 2 1 1 3 3 3 3 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4795 PF16043.5 EPS33711.1 - 0.0078 15.8 3.2 0.019 14.6 3.2 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4795) DASH_Dad1 PF08649.10 EPS33711.1 - 0.074 13.2 0.3 0.16 12.2 0.3 1.6 1 0 0 1 1 1 0 DASH complex subunit Dad1 DUF4472 PF14739.6 EPS33711.1 - 0.14 12.9 8.1 0.1 13.3 2.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) SlyX PF04102.12 EPS33711.1 - 0.16 12.6 6.2 0.35 11.5 0.8 2.4 2 0 0 2 2 2 0 SlyX V_ATPase_I PF01496.19 EPS33711.1 - 0.22 9.4 1.2 0.25 9.2 1.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family XhlA PF10779.9 EPS33711.1 - 0.24 11.6 8.0 0.22 11.8 1.4 2.3 2 0 0 2 2 2 0 Haemolysin XhlA WDCP PF15390.6 EPS33711.1 - 0.48 8.8 2.7 0.58 8.5 2.7 1.0 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family APG6_N PF17675.1 EPS33711.1 - 1 9.9 12.2 1.5 9.4 12.2 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region Fis1_TPR_C PF14853.6 EPS33712.1 - 2.4e-25 88.3 1.4 3.7e-25 87.8 1.4 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 EPS33712.1 - 1.2e-16 60.0 0.0 2.1e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.17 EPS33712.1 - 0.0099 15.9 2.3 0.0099 15.9 2.3 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-RING_2 PF13639.6 EPS33713.1 - 5.1e-13 49.1 8.9 5.1e-13 49.1 8.9 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_11 PF17123.5 EPS33713.1 - 3.1e-11 42.8 4.3 6.3e-11 41.8 4.3 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EPS33713.1 - 2e-08 33.9 8.5 2e-08 33.9 8.5 2.1 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EPS33713.1 - 3.2e-08 33.7 7.3 3.2e-08 33.7 7.3 1.8 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EPS33713.1 - 8.2e-08 32.0 3.5 8.2e-08 32.0 3.5 2.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPS33713.1 - 6.1e-07 29.2 12.1 7.5e-07 28.9 7.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EPS33713.1 - 1.7e-05 24.7 2.9 1.7e-05 24.7 2.9 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zinc_ribbon_9 PF14369.6 EPS33713.1 - 1.9e-05 24.8 5.3 0.00023 21.3 0.5 2.7 2 0 0 2 2 2 1 zinc-ribbon zf-RING_5 PF14634.6 EPS33713.1 - 0.00012 21.9 5.6 0.00012 21.9 5.6 2.3 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EPS33713.1 - 0.00021 21.1 5.8 0.00021 21.1 5.8 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EPS33713.1 - 0.008 16.2 3.0 0.008 16.2 3.0 1.8 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EPS33713.1 - 0.026 14.3 4.5 0.026 14.3 4.5 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain HypA PF01155.19 EPS33713.1 - 0.14 12.2 2.9 2.4 8.2 0.1 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-TFIIB PF13453.6 EPS33713.1 - 0.6 9.5 9.1 0.16 11.4 1.2 3.2 3 0 0 3 3 3 0 Transcription factor zinc-finger Zn_ribbon_17 PF17120.5 EPS33713.1 - 0.62 9.7 11.5 0.12 12.1 7.6 1.7 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 EPS33713.1 - 0.67 10.1 9.3 2 8.6 9.3 1.8 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.29 EPS33713.1 - 0.79 9.7 14.1 0.16 11.9 7.3 2.4 2 0 0 2 2 2 0 PHD-finger Zn_Tnp_IS1595 PF12760.7 EPS33713.1 - 0.99 9.4 6.1 10 6.2 0.1 2.8 3 0 0 3 3 3 0 Transposase zinc-ribbon domain zf-C3HC4_4 PF15227.6 EPS33713.1 - 5.9 7.1 9.8 1.6 8.9 4.1 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 EPS33713.1 - 8.1 6.7 10.9 4.7 7.5 7.0 2.6 3 1 0 3 3 2 0 FANCL C-terminal domain Aminotran_5 PF00266.19 EPS33714.1 - 2.1e-21 76.3 0.0 3.3e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EPS33714.1 - 0.0073 15.7 0.0 0.42 9.9 0.0 2.2 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family DUF4043 PF13252.6 EPS33714.1 - 0.033 13.3 0.0 2.4 7.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4043) SepSecS PF05889.13 EPS33714.1 - 0.12 11.1 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS bZIP_1 PF00170.21 EPS33715.1 - 1.2e-05 25.3 2.6 3.2e-05 23.9 2.6 1.7 1 0 0 1 1 1 1 bZIP transcription factor Phosphoesterase PF04185.14 EPS33716.1 - 3.2e-31 108.8 4.2 8.3e-31 107.5 4.2 1.5 1 1 0 1 1 1 1 Phosphoesterase family Activator_LAG-3 PF11498.8 EPS33716.1 - 0.088 11.8 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF2475 PF10629.9 EPS33716.1 - 0.1 12.8 0.5 0.23 11.7 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2475) GYF PF02213.16 EPS33717.1 - 1.8e-18 65.9 0.4 4e-18 64.8 0.4 1.6 1 0 0 1 1 1 1 GYF domain MRP-S27 PF10037.9 EPS33717.1 - 0.63 8.8 4.4 1.6 7.5 4.4 1.7 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Homeodomain PF00046.29 EPS33717.1 - 1.9 8.4 5.1 1 9.3 2.4 1.9 2 0 0 2 2 2 0 Homeodomain ADH_zinc_N PF00107.26 EPS33719.1 - 7.5e-24 84.2 0.7 1.4e-23 83.3 0.7 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPS33719.1 - 1.7e-10 42.1 0.1 3.3e-10 41.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPS33719.1 - 3.1e-05 23.8 0.0 5.9e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_7 PF13241.6 EPS33719.1 - 0.02 15.3 0.8 8.3 6.9 0.1 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding adh_short PF00106.25 EPS33719.1 - 0.031 13.7 0.8 0.076 12.5 0.8 1.6 1 0 0 1 1 1 0 short chain dehydrogenase Trp_syntA PF00290.20 EPS33723.1 - 4e-95 317.6 0.0 6.6e-95 316.8 0.0 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 EPS33723.1 - 2.2e-51 175.0 1.9 3.5e-51 174.4 1.9 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ATP-synt_ab PF00006.25 EPS33724.1 - 6.7e-69 231.8 0.0 9.3e-69 231.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EPS33724.1 - 1.4e-12 48.0 0.2 2.7e-12 47.0 0.2 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain 2-Hacid_dh_C PF02826.19 EPS33725.1 - 4.8e-46 156.4 0.0 8.6e-46 155.5 0.0 1.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 EPS33725.1 - 0.00014 22.0 0.0 0.00043 20.4 0.0 1.7 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh PF00389.30 EPS33725.1 - 0.0023 17.6 0.0 0.0068 16.1 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ELFV_dehydrog PF00208.21 EPS33725.1 - 0.043 13.5 0.0 0.06 13.0 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Yae1_N PF09811.9 EPS33727.1 - 0.00057 19.5 15.0 0.0011 18.6 15.0 1.5 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Usp PF00582.26 EPS33728.1 - 3.1e-18 66.7 7.8 4.1e-17 63.0 0.7 4.1 2 1 0 2 2 2 1 Universal stress protein family EF-1_beta_acid PF10587.9 EPS33728.1 - 0.089 13.3 0.4 0.089 13.3 0.4 6.0 6 0 0 6 6 6 0 Eukaryotic elongation factor 1 beta central acidic region NOA36 PF06524.12 EPS33728.1 - 1.9 7.8 19.7 3.4 6.9 19.7 1.4 1 0 0 1 1 1 0 NOA36 protein DnaJ PF00226.31 EPS33730.1 - 2e-22 79.1 1.3 5.6e-22 77.6 1.3 1.8 1 0 0 1 1 1 1 DnaJ domain DUF493 PF04359.14 EPS33730.1 - 0.06 13.9 0.0 0.17 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF493) Inv-AAD PF18785.1 EPS33731.1 - 2.2e-42 144.0 0.0 3.2e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase dCMP_cyt_deam_1 PF00383.23 EPS33731.1 - 1.3e-11 44.2 0.0 9.8e-11 41.4 0.0 2.1 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.11 EPS33731.1 - 1.5e-05 25.0 0.0 2.9e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 APOBEC-like N-terminal domain SNAD4 PF18750.1 EPS33731.1 - 0.011 15.8 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 Stn1 PF10451.9 EPS33732.1 - 8.7e-13 47.8 0.0 2.4e-08 33.2 0.0 2.2 2 0 0 2 2 2 2 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.25 EPS33732.1 - 0.011 15.7 0.0 1.6 8.8 0.0 2.6 3 0 0 3 3 3 0 OB-fold nucleic acid binding domain Spt5_N PF11942.8 EPS33732.1 - 0.032 15.2 4.3 0.066 14.2 4.3 1.5 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DUF2570 PF10828.8 EPS33732.1 - 0.08 12.8 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Pkinase PF00069.25 EPS33736.1 - 2.7e-56 190.9 0.0 4.3e-56 190.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS33736.1 - 3.5e-31 108.4 0.0 3e-29 102.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EPS33736.1 - 0.0027 16.7 0.0 0.0042 16.1 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 EPS33736.1 - 0.1 11.5 0.0 0.14 11.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RNase_PH PF01138.21 EPS33737.1 - 5e-12 46.5 0.0 1.7e-11 44.8 0.0 1.9 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EPS33737.1 - 0.1 12.7 0.1 0.28 11.3 0.0 1.7 2 0 0 2 2 2 0 3' exoribonuclease family, domain 2 Cytochrom_C PF00034.21 EPS33739.1 - 2.2e-13 51.2 0.1 3e-13 50.7 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 EPS33739.1 - 5.2e-08 33.1 2.8 3e-07 30.6 2.8 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 EPS33739.1 - 8.6e-05 22.3 0.6 0.00013 21.7 0.6 1.7 1 1 0 1 1 1 1 Cytochrome c-550 domain Cytochrome-c551 PF10643.9 EPS33739.1 - 0.08 12.5 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 CCP_MauG PF03150.14 EPS33739.1 - 0.097 13.3 0.0 0.11 13.1 0.0 1.2 1 0 0 1 1 1 0 Di-haem cytochrome c peroxidase ParB_C PF18064.1 EPS33740.1 - 0.028 14.6 0.8 0.069 13.3 0.0 2.1 2 0 0 2 2 2 0 Centromere-binding protein ParB C-terminal Baculo_PEP_C PF04513.12 EPS33740.1 - 0.14 12.2 2.4 0.38 10.8 0.2 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATE_C PF04377.15 EPS33741.1 - 4.9e-48 163.2 1.3 1e-47 162.1 1.3 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 EPS33741.1 - 5.8e-21 74.7 6.9 1.4e-20 73.5 5.9 2.0 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.7 EPS33741.1 - 0.023 14.9 0.5 0.041 14.0 0.5 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-Dof PF02701.15 EPS33741.1 - 0.055 13.6 1.5 0.16 12.2 1.5 1.8 1 0 0 1 1 1 0 Dof domain, zinc finger NUDIX PF00293.28 EPS33742.1 - 1.9e-18 66.8 0.1 2.3e-18 66.5 0.1 1.0 1 0 0 1 1 1 1 NUDIX domain RNA_pol_A_bac PF01000.26 EPS33743.1 - 1.9e-30 105.5 0.0 3.2e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EPS33743.1 - 5.8e-15 54.5 0.0 7.4e-15 54.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain LPD7 PF18821.1 EPS33745.1 - 0.047 13.8 0.8 0.12 12.6 0.7 1.7 1 1 0 1 1 1 0 Large polyvalent protein-associated domain 7 HECT_2 PF09814.9 EPS33745.1 - 0.069 12.0 0.1 0.093 11.6 0.1 1.2 1 0 0 1 1 1 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Calcipressin PF04847.12 EPS33746.1 - 5.2e-34 117.6 1.8 7.5e-34 117.1 1.8 1.3 1 0 0 1 1 1 1 Calcipressin Lipase_3 PF01764.25 EPS33747.1 - 6.4e-36 123.3 0.1 1e-35 122.6 0.1 1.3 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.20 EPS33747.1 - 0.0027 17.9 0.1 0.0041 17.3 0.1 1.3 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 EPS33747.1 - 0.0074 16.0 0.0 0.0094 15.6 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 EPS33747.1 - 0.0086 15.4 0.1 0.014 14.6 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2974 PF11187.8 EPS33747.1 - 0.012 15.2 0.9 0.046 13.3 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) PE-PPE PF08237.11 EPS33747.1 - 0.018 14.6 1.7 0.02 14.5 0.6 1.7 1 1 1 2 2 2 0 PE-PPE domain FATC PF02260.20 EPS33747.1 - 0.2 11.5 1.1 3.6 7.5 0.3 2.8 2 0 0 2 2 2 0 FATC domain Metallopep PF12044.8 EPS33748.1 - 8e-126 420.1 0.0 1.1e-125 419.6 0.0 1.2 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_3 PF13582.6 EPS33748.1 - 0.0017 18.9 0.3 0.0056 17.2 0.3 1.9 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 EPS33748.1 - 0.0059 16.8 0.4 0.012 15.7 0.4 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.6 EPS33748.1 - 0.0071 16.3 0.2 0.014 15.3 0.2 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 EPS33748.1 - 0.021 14.4 0.1 0.05 13.2 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 EPS33748.1 - 0.088 11.7 0.3 0.16 10.9 0.3 1.3 1 0 0 1 1 1 0 Peptidase M66 RCC1_2 PF13540.6 EPS33748.1 - 0.16 11.8 0.4 0.71 9.8 0.2 2.1 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat GrpE PF01025.19 EPS33749.1 - 3.9e-44 150.2 5.6 5.9e-44 149.7 5.6 1.2 1 0 0 1 1 1 1 GrpE NPH3 PF03000.14 EPS33749.1 - 0.017 14.8 0.2 0.026 14.2 0.2 1.3 1 0 0 1 1 1 0 NPH3 family KELK PF15796.5 EPS33749.1 - 0.15 12.5 0.1 0.15 12.5 0.1 2.7 2 1 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase tRNA-synt_2d PF01409.20 EPS33750.1 - 5.5e-46 157.0 0.1 3.2e-25 89.0 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 EPS33750.1 - 1.1e-27 96.3 0.0 3.6e-27 94.6 0.0 1.9 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain Mito_carr PF00153.27 EPS33751.1 - 1.7e-59 197.8 0.3 1.5e-19 69.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein COX6B PF02297.17 EPS33752.1 - 2.1e-18 66.3 8.1 2.4e-18 66.1 8.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.14 EPS33752.1 - 0.022 14.7 0.6 0.032 14.2 0.6 1.3 1 0 0 1 1 1 0 APOBEC-like C-terminal domain mRNA_stabil PF13929.6 EPS33752.1 - 0.08 11.9 0.0 0.091 11.7 0.0 1.0 1 0 0 1 1 1 0 mRNA stabilisation ketoacyl-synt PF00109.26 EPS33752.1 - 0.089 12.4 0.0 0.089 12.4 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain T2SSJ PF11612.8 EPS33752.1 - 0.1 12.8 0.3 9.8 6.4 0.1 2.0 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein J B12D PF06522.11 EPS33753.1 - 0.0015 18.3 0.0 0.003 17.3 0.0 1.5 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit RRM_1 PF00076.22 EPS33754.1 - 7.9e-18 64.0 0.0 1.5e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EPS33754.1 - 0.0026 17.8 0.0 0.0042 17.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif Limkain-b1 PF11608.8 EPS33754.1 - 0.046 13.8 0.0 0.089 12.9 0.0 1.4 1 0 0 1 1 1 0 Limkain b1 Nup35_RRM_2 PF14605.6 EPS33754.1 - 0.18 11.8 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif SRA1 PF07304.11 EPS33755.1 - 2.6e-11 43.5 0.0 2.6e-11 43.5 0.0 3.1 3 1 1 4 4 4 1 Steroid receptor RNA activator (SRA1) WD40 PF00400.32 EPS33755.1 - 2.2e-05 25.1 3.5 1.3 10.1 0.0 5.6 5 0 0 5 5 5 1 WD domain, G-beta repeat Sec16_C PF12931.7 EPS33755.1 - 2.6e-05 24.0 0.2 0.00024 20.9 0.2 2.1 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 ANAPC4_WD40 PF12894.7 EPS33755.1 - 0.0018 18.6 0.5 0.02 15.2 0.1 3.0 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Prp18 PF02840.15 EPS33755.1 - 0.065 13.3 0.1 0.22 11.5 0.1 1.9 1 1 0 1 1 1 0 Prp18 domain Pex14_N PF04695.13 EPS33756.1 - 7.7e-44 150.1 0.8 7.7e-44 150.1 0.8 2.9 3 0 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region PAPA-1 PF04795.12 EPS33757.1 - 4.3e-32 110.8 4.8 4.3e-32 110.8 4.8 3.1 3 0 0 3 3 3 1 PAPA-1-like conserved region Mus7 PF09462.10 EPS33758.1 - 3e-189 630.9 1.6 3e-189 630.9 1.6 1.6 2 0 0 2 2 2 1 Mus7/MMS22 family DUF4050 PF13259.6 EPS33759.1 - 9.2e-55 185.8 19.4 2.4e-54 184.5 19.4 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF4050) AAA PF00004.29 EPS33760.1 - 3.8e-39 134.1 0.1 1.8e-37 128.7 0.0 2.8 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EPS33760.1 - 2.2e-08 33.7 0.2 7e-08 32.2 0.2 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_33 PF13671.6 EPS33760.1 - 7.4e-05 22.9 0.3 0.003 17.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.12 EPS33760.1 - 0.00011 22.0 0.0 0.00023 20.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EPS33760.1 - 0.00022 21.7 3.2 0.0012 19.3 0.1 3.6 2 2 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EPS33760.1 - 0.00028 21.2 0.5 0.043 14.1 0.1 3.4 2 1 0 3 3 3 1 AAA domain TIP49 PF06068.13 EPS33760.1 - 0.00057 19.2 0.2 0.002 17.4 0.0 1.9 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_5 PF07728.14 EPS33760.1 - 0.0021 18.1 0.0 0.0051 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EPS33760.1 - 0.0073 16.3 0.0 0.045 13.8 0.0 2.2 2 1 1 3 3 3 1 AAA domain IstB_IS21 PF01695.17 EPS33760.1 - 0.0078 16.0 0.0 0.021 14.6 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EPS33760.1 - 0.018 14.5 0.1 0.048 13.0 0.1 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EPS33760.1 - 0.031 14.5 0.0 0.085 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EPS33760.1 - 0.04 14.3 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 EPS33760.1 - 0.043 14.2 0.2 0.34 11.3 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EPS33760.1 - 0.055 14.0 0.0 0.17 12.5 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.6 EPS33760.1 - 0.08 12.6 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 EPS33760.1 - 0.097 11.7 0.0 0.26 10.3 0.0 1.7 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 TsaE PF02367.17 EPS33760.1 - 0.12 12.4 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE LIM_bind PF01803.16 EPS33761.1 - 1.2e-70 237.7 1.0 1.2e-70 237.7 1.0 4.0 2 1 1 3 3 3 1 LIM-domain binding protein cobW PF02492.19 EPS33762.1 - 1.5e-33 115.8 0.0 1.9e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EPS33762.1 - 2e-05 23.7 1.1 0.00029 19.9 1.1 2.0 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MMR_HSR1 PF01926.23 EPS33762.1 - 0.0025 17.9 0.0 0.0072 16.4 0.0 1.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EPS33762.1 - 0.018 15.5 0.0 0.025 15.0 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 EPS33762.1 - 0.02 14.9 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 EPS33762.1 - 0.031 14.8 0.0 0.041 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EPS33762.1 - 0.034 13.9 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein CbiA PF01656.23 EPS33762.1 - 0.065 13.3 0.0 0.11 12.5 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.12 EPS33762.1 - 0.085 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ResIII PF04851.15 EPS33762.1 - 0.15 12.0 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit ABC_tran PF00005.27 EPS33762.1 - 0.16 12.5 0.0 0.21 12.1 0.0 1.2 1 0 0 1 1 1 0 ABC transporter ATPase_2 PF01637.18 EPS33762.1 - 0.17 11.8 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea BING4CT PF08149.11 EPS33763.1 - 8.5e-38 128.0 0.0 7.7e-35 118.6 0.0 2.8 3 0 0 3 3 3 2 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 EPS33763.1 - 6e-08 32.9 0.0 0.22 11.8 0.0 5.6 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EPS33763.1 - 0.00057 20.6 0.0 0.27 12.2 0.0 4.0 4 0 0 4 4 4 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 EPS33763.1 - 0.024 13.7 0.0 0.057 12.4 0.0 1.5 2 0 0 2 2 2 0 Coatomer WD associated region RIBIOP_C PF04950.12 EPS33764.1 - 1e-108 363.2 0.1 2.4e-108 362.0 0.0 1.7 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EPS33764.1 - 9.3e-22 76.9 0.0 3.4e-21 75.1 0.0 2.0 2 0 0 2 2 2 1 AARP2CN (NUC121) domain SNAP PF14938.6 EPS33765.1 - 4.3e-116 387.3 16.3 4.9e-116 387.1 16.3 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 EPS33765.1 - 1.3e-07 31.8 13.6 0.0012 19.1 0.5 4.3 2 2 2 4 4 4 3 Tetratricopeptide repeat Spatacsin_C PF14649.6 EPS33765.1 - 0.002 17.3 10.3 1.7 7.7 0.0 3.0 1 1 1 2 2 2 2 Spatacsin C-terminus TPR_7 PF13176.6 EPS33765.1 - 0.0024 17.8 12.5 0.082 13.0 0.7 5.1 5 1 0 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EPS33765.1 - 0.0025 17.8 19.9 0.12 12.6 1.0 7.1 3 1 5 8 8 8 2 Tetratricopeptide repeat DUF2811 PF10929.8 EPS33765.1 - 0.011 16.0 0.2 0.033 14.5 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) DUF5344 PF17279.2 EPS33765.1 - 0.014 15.9 2.0 0.58 10.8 0.1 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5344) TPR_6 PF13174.6 EPS33765.1 - 0.019 15.6 17.7 0.32 11.7 1.1 6.2 5 1 2 7 7 6 0 Tetratricopeptide repeat MIT PF04212.18 EPS33765.1 - 0.023 14.8 7.1 8.3 6.6 0.6 3.9 1 1 2 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 EPS33765.1 - 0.044 13.6 20.0 0.46 10.4 1.1 6.4 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 EPS33765.1 - 0.086 13.1 0.7 0.086 13.1 0.7 5.6 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 EPS33765.1 - 0.13 13.1 13.9 0.8 10.7 2.4 4.9 2 1 4 6 6 6 0 Tetratricopeptide repeat NSF PF02071.20 EPS33765.1 - 7.1 7.9 20.7 6.2 8.1 0.3 6.7 7 0 0 7 7 6 0 Aromatic-di-Alanine (AdAR) repeat Glu-tRNAGln PF02686.15 EPS33766.1 - 7.6e-12 45.4 0.1 1.1e-11 44.8 0.1 1.3 1 0 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit DUF726 PF05277.12 EPS33767.1 - 2.1e-100 336.0 13.1 4.3e-92 308.7 0.2 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF726) Thioesterase PF00975.20 EPS33767.1 - 0.0047 17.1 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain DUF900 PF05990.12 EPS33767.1 - 0.061 12.8 0.3 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Cutinase PF01083.22 EPS33767.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Cutinase Glyoxal_oxid_N PF07250.11 EPS33767.1 - 0.17 11.1 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus ADH_zinc_N_2 PF13602.6 EPS33768.1 - 6.8e-29 101.6 0.0 1.4e-28 100.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EPS33768.1 - 2.8e-16 59.7 0.0 4.6e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPS33768.1 - 0.00013 21.8 0.1 0.02 14.8 0.0 3.2 2 2 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Sulfatase PF00884.23 EPS33769.1 - 3.1e-62 210.7 1.1 3.9e-62 210.4 1.1 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 EPS33769.1 - 0.00022 21.0 1.9 0.00062 19.5 1.9 1.6 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4976 PF16347.5 EPS33769.1 - 0.00044 20.5 0.1 0.00091 19.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4976) DUF229 PF02995.17 EPS33769.1 - 0.015 13.9 0.2 0.05 12.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF229) Glyco_hydro_75 PF07335.11 EPS33771.1 - 5.6e-45 153.5 0.2 8.9e-45 152.9 0.2 1.3 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 Ribosomal_L33 PF00471.20 EPS33772.1 - 1.7e-05 25.1 0.1 2.1e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 HALZ PF02183.18 EPS33773.1 - 2.8 8.3 12.7 11 6.3 0.8 4.9 4 0 0 4 4 4 0 Homeobox associated leucine zipper Pkinase PF00069.25 EPS33774.1 - 3.7e-62 210.1 0.0 5.1e-62 209.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS33774.1 - 3.6e-33 114.9 0.0 4.7e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EPS33774.1 - 5.4e-06 25.9 0.0 9e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EPS33774.1 - 0.00079 19.4 2.3 0.0011 19.0 0.1 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EPS33774.1 - 0.0031 16.9 0.1 0.0052 16.2 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EPS33774.1 - 0.021 13.8 0.0 0.029 13.3 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 EPS33774.1 - 0.042 12.6 0.0 0.076 11.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Endonuc_Holl PF10107.9 EPS33774.1 - 0.14 12.0 0.1 0.93 9.3 0.0 2.0 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase KAR9 PF08580.10 EPS33774.1 - 1.6 7.2 13.0 2.5 6.5 13.0 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 SPX PF03105.19 EPS33774.1 - 4 7.2 7.1 5.4 6.8 7.1 1.2 1 0 0 1 1 1 0 SPX domain SOG2 PF10428.9 EPS33774.1 - 6.5 5.8 11.4 8.7 5.4 11.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Cellulase PF00150.18 EPS33775.1 - 2.5e-14 53.4 3.7 2.5e-14 53.4 3.7 1.7 1 1 1 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Response_reg PF00072.24 EPS33776.1 - 1.7e-18 66.8 0.0 5.4e-18 65.2 0.0 1.9 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 EPS33776.1 - 7.8e-18 65.0 0.0 1.7e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EPS33776.1 - 1.2e-13 50.8 1.2 3.4e-13 49.4 1.2 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.11 EPS33776.1 - 4.9e-06 27.2 0.0 1.6e-05 25.5 0.0 1.9 1 0 0 1 1 1 1 PAS fold PHY PF00360.20 EPS33776.1 - 0.00015 21.1 0.1 0.002 17.5 0.0 2.7 2 1 1 3 3 3 1 Phytochrome region HATPase_c_2 PF13581.6 EPS33776.1 - 0.0029 17.5 0.0 0.0061 16.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain GAF PF01590.26 EPS33776.1 - 0.006 17.2 0.1 0.039 14.6 0.0 2.4 3 0 0 3 3 3 1 GAF domain HATPase_c_3 PF13589.6 EPS33776.1 - 0.067 13.0 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SNF2_N PF00176.23 EPS33778.1 - 6.2e-67 225.8 0.0 1.3e-65 221.5 0.0 2.3 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EPS33778.1 - 3.3e-16 59.6 0.0 1.3e-15 57.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPS33778.1 - 2.2e-09 37.5 0.8 5.1e-09 36.3 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_34 PF13872.6 EPS33778.1 - 0.084 11.8 0.2 0.5 9.2 0.2 2.0 1 1 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 BUD22 PF09073.10 EPS33778.1 - 0.33 10.3 31.7 1.9 7.7 13.6 2.8 2 0 0 2 2 2 0 BUD22 SIR2 PF02146.17 EPS33779.1 - 7.5e-40 136.7 0.0 2e-39 135.3 0.0 1.6 1 1 0 1 1 1 1 Sir2 family Dynamin_N PF00350.23 EPS33780.1 - 1.5e-30 106.4 0.2 5.3e-30 104.7 0.0 2.0 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.20 EPS33780.1 - 5.3e-22 78.4 0.1 2.5e-17 63.0 0.2 2.5 1 1 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.23 EPS33780.1 - 0.0015 18.6 0.1 0.012 15.7 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase GED PF02212.18 EPS33780.1 - 0.0072 16.4 0.3 0.0072 16.4 0.3 3.9 4 1 0 4 4 4 1 Dynamin GTPase effector domain AAA_15 PF13175.6 EPS33780.1 - 0.01 15.6 0.6 0.72 9.5 0.0 3.0 3 0 0 3 3 3 0 AAA ATPase domain DUF3510 PF12022.8 EPS33780.1 - 0.038 14.4 1.7 0.47 10.8 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3510) AIG1 PF04548.16 EPS33780.1 - 0.14 11.5 3.6 5.4 6.3 0.1 3.4 2 1 2 4 4 4 0 AIG1 family FlxA PF14282.6 EPS33780.1 - 0.97 9.5 6.7 11 6.1 0.9 2.5 2 0 0 2 2 2 0 FlxA-like protein Pyridox_ox_2 PF12900.7 EPS33781.1 - 3.5e-38 130.8 0.0 4.7e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Peptidase_M24 PF00557.24 EPS33782.1 - 2.9e-48 164.3 0.0 4.4e-48 163.8 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EPS33782.1 - 2.3e-37 127.5 0.0 3.9e-37 126.7 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain RuBisCO_large PF00016.20 EPS33782.1 - 0.0048 16.1 0.0 0.0076 15.5 0.0 1.2 1 0 0 1 1 1 1 Ribulose bisphosphate carboxylase large chain, catalytic domain Dfp1_Him1_M PF08630.10 EPS33783.1 - 3.4e-40 137.2 0.0 9.8e-40 135.7 0.0 1.8 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.12 EPS33783.1 - 6.4e-21 74.2 0.2 1.3e-20 73.2 0.2 1.6 1 0 0 1 1 1 1 DBF zinc finger PTCB-BRCT PF12738.7 EPS33783.1 - 0.0081 16.1 0.0 0.022 14.7 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain Ank_2 PF12796.7 EPS33784.1 - 9.3e-29 99.9 0.4 1.9e-08 34.8 0.0 7.1 4 1 3 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPS33784.1 - 1.5e-26 92.4 2.0 4.9e-10 39.7 0.0 9.1 8 2 1 9 9 9 4 Ankyrin repeats (many copies) Ank PF00023.30 EPS33784.1 - 6.4e-19 67.5 8.6 0.11 13.0 0.4 11.0 10 0 0 10 10 10 4 Ankyrin repeat Pkinase PF00069.25 EPS33784.1 - 1.7e-18 67.0 0.0 2.7e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ank_3 PF13606.6 EPS33784.1 - 1.8e-18 64.7 2.0 0.0098 16.3 0.0 9.5 11 0 0 11 11 11 4 Ankyrin repeat Ank_5 PF13857.6 EPS33784.1 - 1.3e-17 63.6 4.3 4.3e-05 23.7 0.2 7.7 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Pkinase_Tyr PF07714.17 EPS33784.1 - 9.7e-15 54.5 0.0 1.6e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EPS33784.1 - 0.046 12.5 0.0 0.072 11.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase HeLo PF14479.6 EPS33785.1 - 1.3e-06 28.4 3.1 3.2e-06 27.1 3.1 1.6 1 1 0 1 1 1 1 Prion-inhibition and propagation Pkinase_Tyr PF07714.17 EPS33785.1 - 0.0026 17.1 0.0 0.014 14.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pantoate_transf PF02548.15 EPS33786.1 - 5.4e-107 357.0 0.2 6.3e-107 356.8 0.2 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 EPS33786.1 - 5.8e-07 29.2 0.1 1e-06 28.4 0.0 1.4 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF4861 PF16153.5 EPS33786.1 - 0.064 12.2 0.0 0.093 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4861) APG12 PF04110.13 EPS33787.1 - 3.1e-29 101.2 0.0 4.6e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 EPS33787.1 - 0.067 13.4 0.0 0.089 13.0 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like UQ_con PF00179.26 EPS33788.1 - 1.3e-35 122.1 0.1 1.5e-35 121.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme LAMTOR PF15454.6 EPS33789.1 - 1.7e-18 66.9 0.4 3.7e-18 65.9 0.4 1.5 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator SVIP PF15811.5 EPS33789.1 - 0.15 12.5 2.7 1 9.9 0.1 2.5 3 0 0 3 3 3 0 Small VCP/p97-interacting protein DUF2011 PF09428.10 EPS33790.1 - 7.1e-31 106.3 1.4 3.7e-30 104.0 0.0 2.2 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF2011) NUDIX PF00293.28 EPS33790.1 - 0.029 14.4 0.1 0.053 13.6 0.1 1.5 1 0 0 1 1 1 0 NUDIX domain Tht1 PF04163.12 EPS33791.1 - 5.9e-06 25.3 0.9 5.9e-06 25.3 0.9 2.9 1 1 2 3 3 3 1 Tht1-like nuclear fusion protein HigB-like_toxin PF05015.13 EPS33791.1 - 4 7.9 7.2 1.5 9.3 1.1 3.0 2 1 1 3 3 3 0 RelE-like toxin of type II toxin-antitoxin system HigB APH PF01636.23 EPS33792.1 - 5e-10 39.7 0.0 3.2e-09 37.1 0.0 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family DUF4890 PF16231.5 EPS33792.1 - 0.11 13.0 1.9 0.2 12.1 1.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4890) Ferric_reduct PF01794.19 EPS33793.1 - 8.4e-24 84.1 9.0 8.4e-24 84.1 9.0 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 EPS33793.1 - 4e-13 49.8 0.0 5.8e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EPS33793.1 - 1.5e-08 34.6 0.0 3.2e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.21 EPS33793.1 - 4.1e-06 27.4 0.0 1.1e-05 26.0 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Ctr PF04145.15 EPS33794.1 - 1.4e-34 119.8 1.5 1.9e-34 119.4 1.5 1.2 1 0 0 1 1 1 1 Ctr copper transporter family UPF0016 PF01169.19 EPS33794.1 - 0.013 15.8 0.6 0.072 13.4 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein family UPF0016 Babuvirus_MP PF07234.11 EPS33794.1 - 0.22 11.7 0.1 0.22 11.7 0.1 1.8 2 0 0 2 2 2 0 Movement and RNA silencing protein Ribosomal_L6 PF00347.23 EPS33795.1 - 4.7e-24 84.9 0.0 2.9e-11 43.9 0.0 2.8 2 1 0 2 2 2 2 Ribosomal protein L6 Inositol_P PF00459.25 EPS33796.1 - 3.5e-53 180.9 0.3 5.8e-53 180.1 0.3 1.4 1 1 0 1 1 1 1 Inositol monophosphatase family VHS PF00790.19 EPS33797.1 - 3.1e-25 88.7 0.0 8.6e-25 87.2 0.0 1.7 2 1 1 3 3 3 1 VHS domain ENTH PF01417.20 EPS33797.1 - 0.00027 21.0 0.0 0.0021 18.1 0.0 2.1 2 0 0 2 2 2 1 ENTH domain GAT PF03127.14 EPS33797.1 - 0.00036 20.8 0.1 0.00092 19.5 0.1 1.8 1 1 0 1 1 1 1 GAT domain DUF4598 PF15370.6 EPS33797.1 - 0.31 11.5 4.3 0.12 12.9 0.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4598) Ribosomal_60s PF00428.19 EPS33797.1 - 7.3 7.2 6.8 2.3 8.9 1.4 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein ABM PF03992.16 EPS33798.1 - 0.00014 21.9 0.1 0.019 15.1 0.0 2.5 2 0 0 2 2 2 2 Antibiotic biosynthesis monooxygenase Flavoprotein PF02441.19 EPS33799.1 - 1.4e-12 47.6 0.0 2.3e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Flavoprotein MFS_1 PF07690.16 EPS33800.1 - 9.1e-45 153.1 46.1 9.1e-45 153.1 46.1 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS33800.1 - 3.4e-19 69.0 9.2 3.4e-19 69.0 9.2 2.7 3 0 0 3 3 3 2 Sugar (and other) transporter GMC_oxred_N PF00732.19 EPS33801.1 - 1.2e-60 205.4 0.0 1.7e-60 204.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EPS33801.1 - 6.8e-25 88.3 0.0 1.4e-24 87.2 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 EPS33801.1 - 2.1e-08 34.2 0.2 0.0007 19.3 0.0 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EPS33801.1 - 5.9e-07 28.9 0.0 0.0014 17.8 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EPS33801.1 - 2.8e-06 27.4 0.0 7.1e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EPS33801.1 - 8.3e-05 21.8 0.0 0.00013 21.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 EPS33801.1 - 8.5e-05 21.9 0.0 0.00091 18.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EPS33801.1 - 0.00049 19.4 0.6 0.0013 18.1 0.1 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.6 EPS33801.1 - 0.00065 19.0 0.1 0.77 9.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPS33801.1 - 0.013 16.1 0.0 0.27 11.8 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EPS33801.1 - 0.015 14.0 0.0 0.053 12.2 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.14 EPS33801.1 - 0.041 12.7 0.0 0.059 12.2 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase FAD_binding_3 PF01494.19 EPS33801.1 - 0.088 12.0 0.0 0.18 11.0 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain NAD_binding_9 PF13454.6 EPS33801.1 - 0.17 11.9 0.0 0.32 11.0 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_4 PF01565.23 EPS33802.1 - 2.8e-22 78.9 3.7 6.8e-22 77.7 3.7 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EPS33802.1 - 3.8e-11 42.9 0.2 6.4e-11 42.2 0.2 1.4 1 0 0 1 1 1 1 Berberine and berberine like Glyco_hydro_35 PF01301.19 EPS33802.1 - 0.065 12.8 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 UbiA PF01040.18 EPS33803.1 - 2.2e-19 69.8 8.2 4.4e-19 68.8 8.2 1.5 1 1 0 1 1 1 1 UbiA prenyltransferase family p450 PF00067.22 EPS33804.1 - 1.3e-44 152.7 0.0 1.6e-44 152.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Spore_YabQ PF09578.10 EPS33804.1 - 2.3 8.5 10.1 36 4.7 8.0 2.5 2 0 0 2 2 2 0 Spore cortex protein YabQ (Spore_YabQ) adh_short PF00106.25 EPS33805.1 - 2.8e-28 98.7 0.5 3.4e-28 98.5 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS33805.1 - 6.9e-22 78.1 1.1 1.4e-21 77.1 1.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPS33805.1 - 2.5e-12 47.1 0.4 3.7e-12 46.5 0.2 1.5 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 EPS33805.1 - 1.2e-07 31.1 0.1 1.6e-07 30.8 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EPS33805.1 - 7.1e-07 28.9 0.1 2.5e-06 27.1 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EPS33805.1 - 0.0019 18.2 0.5 0.0024 17.8 0.5 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 EPS33805.1 - 0.0021 18.1 0.0 0.0039 17.2 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Tannase PF07519.11 EPS33808.1 - 5.3e-121 404.8 0.7 6.4e-121 404.5 0.7 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 EPS33808.1 - 0.00063 19.1 0.0 0.011 15.0 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 BDM PF10684.9 EPS33808.1 - 0.042 14.2 0.0 0.088 13.2 0.0 1.5 1 0 0 1 1 1 0 Putative biofilm-dependent modulation protein Peptidase_S9 PF00326.21 EPS33808.1 - 0.14 11.7 1.9 0.13 11.7 0.1 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family Tannase PF07519.11 EPS33810.1 - 1.5e-137 459.4 3.4 1.7e-137 459.2 3.4 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase MFS_1 PF07690.16 EPS33812.1 - 1.6e-21 76.6 51.8 1.6e-21 76.6 51.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Gpi16 PF04113.14 EPS33814.1 - 8.3e-240 797.0 0.0 1e-239 796.7 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component LUC7 PF03194.15 EPS33815.1 - 2.7e-74 250.0 0.6 3.3e-74 249.7 0.6 1.0 1 0 0 1 1 1 1 LUC7 N_terminus TelA PF05816.11 EPS33815.1 - 0.0017 17.5 1.3 0.0037 16.4 1.2 1.5 2 0 0 2 2 2 1 Toxic anion resistance protein (TelA) MCPsignal PF00015.21 EPS33815.1 - 0.095 12.5 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain XhlA PF10779.9 EPS33815.1 - 7.3 6.9 6.4 1.7 8.9 0.9 2.1 2 0 0 2 2 2 0 Haemolysin XhlA AP3D1 PF06375.11 EPS33816.1 - 0.018 15.3 7.7 0.02 15.2 7.7 1.1 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Peptidase_S49_N PF08496.10 EPS33816.1 - 0.11 12.6 5.3 0.11 12.5 5.3 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal OAD_gamma PF04277.13 EPS33816.1 - 2.3 8.9 4.3 3 8.5 4.3 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain SPOC PF07744.13 EPS33817.1 - 7.9e-27 94.0 0.0 1.3e-26 93.3 0.0 1.4 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.14 EPS33817.1 - 3.9e-24 85.3 0.3 3.9e-24 85.3 0.3 1.8 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 EPS33817.1 - 3.5e-10 39.6 13.8 7.4e-10 38.6 13.8 1.6 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.6 EPS33817.1 - 0.0047 17.3 0.8 0.018 15.4 0.8 2.0 1 0 0 1 1 1 1 PHD domain of transcriptional enhancer, Asx PHD_2 PF13831.6 EPS33817.1 - 1.9 8.1 9.9 0.46 10.1 6.7 1.6 2 0 0 2 2 2 0 PHD-finger P66_CC PF16563.5 EPS33818.1 - 0.35 10.5 6.4 1.1 9.0 6.4 1.8 1 0 0 1 1 1 0 Coiled-coil and interaction region of P66A and P66B with MBD2 FF PF01846.19 EPS33819.1 - 6.1e-13 48.7 9.7 2.1e-10 40.6 0.4 3.5 3 0 0 3 3 3 3 FF domain WW PF00397.26 EPS33819.1 - 2.7e-10 40.1 2.8 2.7e-09 36.9 1.0 2.7 2 0 0 2 2 2 1 WW domain VGLL4 PF15245.6 EPS33819.1 - 0.053 13.6 0.2 0.15 12.1 0.2 1.7 1 0 0 1 1 1 0 Transcription cofactor vestigial-like protein 4 Proteasome PF00227.26 EPS33820.1 - 8.3e-62 208.1 0.1 1e-61 207.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EPS33820.1 - 2.9e-13 49.2 0.1 8.9e-13 47.7 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF5624 PF18538.1 EPS33820.1 - 0.013 15.6 0.7 0.049 13.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) Nitrate_red_gam PF02665.14 EPS33820.1 - 0.15 11.6 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit SHE3 PF17078.5 EPS33822.1 - 0.032 14.0 2.4 0.04 13.6 2.4 1.1 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 MYO10_CC PF16735.5 EPS33822.1 - 0.11 12.6 10.6 1.2 9.2 3.6 2.3 2 0 0 2 2 2 0 Unconventional myosin-X coiled coil domain Pkinase PF00069.25 EPS33824.1 - 1.7e-28 99.7 0.0 1e-13 51.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EPS33824.1 - 7.4e-08 32.0 0.1 0.0023 17.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Acyl-CoA_dh_1 PF00441.24 EPS33825.1 - 5.3e-33 114.3 0.8 9.2e-33 113.6 0.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EPS33825.1 - 2.8e-23 81.9 0.1 4.5e-23 81.3 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EPS33825.1 - 4.2e-15 56.4 0.1 2.3e-14 54.0 0.0 2.3 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EPS33825.1 - 1e-05 25.8 0.4 1.5e-05 25.3 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain FAD_binding_1 PF00667.20 EPS33826.1 - 3.9e-61 206.4 0.0 6.2e-61 205.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain POR PF01558.18 EPS33826.1 - 1.7e-09 38.0 0.3 7.5e-09 35.9 0.2 2.1 2 0 0 2 2 2 1 Pyruvate ferredoxin/flavodoxin oxidoreductase NAD_binding_1 PF00175.21 EPS33826.1 - 2.7e-09 37.7 0.0 8.4e-09 36.0 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain PFOR_II PF17147.4 EPS33826.1 - 2.4e-05 24.6 0.1 7.7e-05 23.0 0.1 1.9 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Transketolase_C PF02780.20 EPS33826.1 - 0.012 15.5 0.1 0.038 13.9 0.1 1.8 1 0 0 1 1 1 0 Transketolase, C-terminal domain FtsJ PF01728.19 EPS33827.1 - 4.6e-63 212.5 0.0 6.1e-63 212.1 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase DEAD PF00270.29 EPS33828.1 - 7.6e-45 152.8 0.1 1.5e-44 151.8 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPS33828.1 - 3e-28 98.4 0.0 4.5e-27 94.6 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPS33828.1 - 0.0006 19.9 0.3 0.0013 18.7 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EPS33828.1 - 0.14 12.4 0.3 0.48 10.7 0.3 2.0 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.6 EPS33828.1 - 5.5 6.2 9.3 6.7 6.0 0.0 2.7 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit 4HBT PF03061.22 EPS33829.1 - 2.2e-08 34.3 0.0 4.7e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily CAP_N PF01213.19 EPS33829.1 - 0.82 9.1 5.3 1.3 8.5 5.3 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal HECT PF00632.25 EPS33830.1 - 3.9e-76 256.5 0.0 6e-76 255.9 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HEAT PF02985.22 EPS33830.1 - 0.011 15.9 1.9 4.8 7.7 0.0 4.9 4 1 1 5 5 5 0 HEAT repeat Arm PF00514.23 EPS33830.1 - 0.057 13.5 7.3 64 3.8 0.0 5.9 5 1 1 6 6 6 0 Armadillo/beta-catenin-like repeat Telomere_reg-2 PF10193.9 EPS33830.1 - 0.072 13.5 0.6 16 6.0 0.0 3.6 3 1 1 4 4 4 0 Telomere length regulation protein Response_reg PF00072.24 EPS33832.1 - 1.6e-24 86.2 0.3 2.9e-24 85.4 0.3 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 EPS33832.1 - 4.7e-20 72.2 0.0 9.6e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EPS33832.1 - 3.3e-13 49.5 0.1 1.1e-12 47.7 0.1 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain LCE6A PF15858.5 EPS33832.1 - 0.56 11.0 2.8 1.5 9.6 2.8 1.6 1 0 0 1 1 1 0 Late cornified envelope protein 6A family CTP_transf_like PF01467.26 EPS33833.1 - 6.5e-26 91.2 0.0 9.7e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like SIS PF01380.22 EPS33834.1 - 2e-12 47.1 0.0 6.7e-11 42.2 0.0 2.2 2 0 0 2 2 2 1 SIS domain SIS_2 PF13580.6 EPS33834.1 - 1.6e-08 34.6 0.0 2.1e-06 27.8 0.0 2.4 1 1 1 2 2 2 2 SIS domain Ubie_methyltran PF01209.18 EPS33835.1 - 4.8e-82 274.8 0.0 6.6e-82 274.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EPS33835.1 - 3.4e-17 62.9 0.0 6.8e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS33835.1 - 4.7e-14 52.8 0.0 1e-13 51.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPS33835.1 - 1.2e-12 47.9 0.0 1.6e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPS33835.1 - 1.8e-10 41.4 0.0 3e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPS33835.1 - 2.6e-08 33.9 0.0 3.9e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EPS33835.1 - 0.016 15.0 0.0 0.27 11.0 0.0 2.5 3 0 0 3 3 3 0 Hypothetical methyltransferase Pkinase PF00069.25 EPS33836.1 - 4.6e-07 29.5 0.0 5.7e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS33836.1 - 0.00037 19.9 0.0 0.00047 19.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Gly_transf_sug PF04488.15 EPS33837.1 - 6.6e-11 42.7 0.0 1.2e-10 41.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif UL42 PF17638.2 EPS33838.1 - 0.29 11.1 2.9 0.32 11.0 2.9 1.1 1 0 0 1 1 1 0 HCMV UL42 Glycophorin_A PF01102.18 EPS33839.1 - 1.1e-05 25.6 0.4 2.1e-05 24.7 0.4 1.5 1 0 0 1 1 1 1 Glycophorin A SKG6 PF08693.10 EPS33839.1 - 0.0013 18.1 0.4 0.0028 17.0 0.4 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF5305 PF17231.2 EPS33839.1 - 0.0045 16.4 0.0 0.0064 15.9 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5305) Adeno_E3_CR2 PF02439.15 EPS33839.1 - 0.0086 15.8 0.0 0.015 15.1 0.0 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Podoplanin PF05808.11 EPS33839.1 - 0.0092 16.1 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 Podoplanin TMEM154 PF15102.6 EPS33839.1 - 0.0099 15.8 0.5 0.017 15.0 0.5 1.4 1 0 0 1 1 1 1 TMEM154 protein family DUF3042 PF11240.8 EPS33839.1 - 0.014 15.4 0.3 0.025 14.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) CD34_antigen PF06365.12 EPS33839.1 - 0.02 14.5 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family Phage_holin_2_1 PF04971.12 EPS33839.1 - 0.03 14.3 0.2 0.24 11.4 0.0 2.4 2 1 0 2 2 2 0 Bacteriophage P21 holin S EphA2_TM PF14575.6 EPS33839.1 - 0.042 14.7 0.0 0.085 13.8 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Gram_pos_anchor PF00746.21 EPS33839.1 - 0.074 13.0 1.0 0.13 12.2 1.0 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Amnionless PF14828.6 EPS33839.1 - 0.079 11.8 0.0 0.098 11.5 0.0 1.1 1 0 0 1 1 1 0 Amnionless Syndecan PF01034.20 EPS33839.1 - 0.18 11.7 0.5 0.32 10.9 0.5 1.3 1 0 0 1 1 1 0 Syndecan domain MGC-24 PF05283.11 EPS33839.1 - 0.86 10.1 12.6 3.7 8.0 12.6 2.1 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin APH PF01636.23 EPS33840.1 - 4.9e-19 69.2 0.0 6.4e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPS33840.1 - 0.0014 18.3 0.0 0.0024 17.5 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 EPS33840.1 - 0.061 12.9 0.0 0.41 10.2 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Y_phosphatase3 PF13350.6 EPS33841.1 - 1.1e-58 198.9 0.0 1.3e-58 198.7 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EPS33841.1 - 0.0016 18.1 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 EPS33841.1 - 0.0022 17.6 0.0 0.0036 16.9 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 EPS33841.1 - 0.0095 16.1 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Coat_F PF07875.12 EPS33841.1 - 0.18 12.1 0.0 4.4 7.6 0.0 2.5 3 0 0 3 3 3 0 Coat F domain Ig_mannosidase PF17753.1 EPS33842.1 - 1.4e-24 85.6 1.3 2.2e-24 85.0 0.1 2.0 2 0 0 2 2 2 1 Ig-fold domain Mannosidase_ig PF17786.1 EPS33842.1 - 1.9e-14 54.0 0.1 6.5e-14 52.3 0.1 2.0 1 0 0 1 1 1 1 Mannosidase Ig/CBM-like domain Glyco_hydro_2 PF00703.21 EPS33842.1 - 4e-07 30.7 0.0 1.3e-06 29.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Ig_GlcNase PF18368.1 EPS33842.1 - 0.00075 19.6 0.0 0.0026 17.9 0.0 1.9 2 0 0 2 2 2 1 Exo-beta-D-glucosaminidase Ig-fold domain Glyco_hydro_2_C PF02836.17 EPS33842.1 - 0.031 13.4 0.0 0.13 11.3 0.0 1.8 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Lyx_isomer PF07385.12 EPS33843.1 - 0.11 11.7 0.5 0.35 10.1 0.0 2.1 2 0 0 2 2 2 0 D-lyxose isomerase E1_dh PF00676.20 EPS33844.1 - 2e-90 302.8 0.0 2.5e-90 302.5 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 EPS33844.1 - 3.5e-05 23.6 0.2 0.00087 19.1 0.0 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain XFP_N PF09364.10 EPS33844.1 - 0.038 12.8 0.0 0.061 12.1 0.0 1.3 1 0 0 1 1 1 0 XFP N-terminal domain DXP_synthase_N PF13292.6 EPS33844.1 - 0.073 12.3 0.0 0.27 10.4 0.0 1.8 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase EnY2 PF10163.9 EPS33844.1 - 0.18 12.2 1.1 0.33 11.3 1.1 1.4 1 0 0 1 1 1 0 Transcription factor e(y)2 Rieske PF00355.26 EPS33845.1 - 2.7e-08 33.7 0.0 4.2e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 EPS33845.1 - 0.00027 20.8 0.0 0.0004 20.3 0.0 1.2 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain HAP2-GCS1 PF10699.9 EPS33845.1 - 0.077 13.0 0.2 6.6 6.8 0.0 2.3 2 0 0 2 2 2 0 Male gamete fusion factor zf-RING_4 PF14570.6 EPS33846.1 - 8e-20 70.4 13.8 1.4e-19 69.6 13.8 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 EPS33846.1 - 6.6e-07 29.1 7.3 1.1e-06 28.3 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 EPS33846.1 - 0.0001 22.0 0.0 0.00024 20.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Baculo_IE-1 PF05290.11 EPS33846.1 - 0.0011 18.9 4.7 0.0019 18.2 4.7 1.3 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-RING_2 PF13639.6 EPS33846.1 - 0.0011 19.2 11.5 0.0022 18.3 11.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EPS33846.1 - 0.24 11.3 12.7 0.45 10.4 12.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EPS33846.1 - 0.28 11.1 10.0 2 8.4 10.2 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DZR PF12773.7 EPS33846.1 - 1.6 8.8 10.1 21 5.2 10.1 2.3 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_UBOX PF13445.6 EPS33846.1 - 5.1 7.2 10.8 11 6.1 10.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Complex1_30kDa PF00329.19 EPS33847.1 - 1.7e-44 151.3 0.0 2.4e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit BUD22 PF09073.10 EPS33848.1 - 4.3e-111 372.3 21.3 4.9e-111 372.1 21.3 1.0 1 0 0 1 1 1 1 BUD22 Fungal_trans PF04082.18 EPS33849.1 - 1.3e-27 96.5 0.1 2.3e-27 95.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS33849.1 - 8e-06 25.9 9.5 1.6e-05 24.9 9.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3119 PF11317.8 EPS33849.1 - 0.095 13.0 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3119) Shikimate_DH PF01488.20 EPS33850.1 - 1.7e-05 24.9 0.0 0.0015 18.6 0.0 2.4 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Proteasome_A_N PF10584.9 EPS33850.1 - 0.038 13.7 0.0 0.098 12.4 0.0 1.7 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature Na_Ca_ex_C PF16494.5 EPS33850.1 - 0.12 12.8 0.0 0.22 12.0 0.0 1.4 1 0 0 1 1 1 0 C-terminal extension of sodium/calcium exchanger domain Pro_dh PF01619.18 EPS33851.1 - 1.1e-63 215.6 0.4 1.7e-63 214.9 0.4 1.3 1 0 0 1 1 1 1 Proline dehydrogenase DUF2856 PF11043.8 EPS33851.1 - 0.018 15.2 0.0 0.04 14.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2856) Aldedh PF00171.22 EPS33852.1 - 1.4e-110 370.0 0.2 1.7e-110 369.7 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family AP_endonuc_2 PF01261.24 EPS33853.1 - 6.5e-42 143.4 0.0 8.5e-42 143.0 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel 6PGD PF00393.19 EPS33854.1 - 4.6e-88 295.3 0.0 5.6e-88 295.1 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EPS33854.1 - 6.5e-35 120.6 0.0 4.8e-34 117.8 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 EPS33854.1 - 7.6e-06 25.9 0.1 1.5e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EPS33854.1 - 0.0013 18.4 0.1 0.0032 17.1 0.1 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 EPS33854.1 - 0.0013 18.1 0.2 0.0033 16.8 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EPS33854.1 - 0.0061 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_11 PF14833.6 EPS33854.1 - 0.009 16.3 0.0 0.032 14.5 0.0 1.9 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase ApbA PF02558.16 EPS33854.1 - 0.024 14.3 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA OCD_Mu_crystall PF02423.15 EPS33854.1 - 0.07 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family PNP_UDP_1 PF01048.20 EPS33855.1 - 1.5e-40 138.9 0.2 1.8e-40 138.7 0.2 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DUF747 PF05346.11 EPS33856.1 - 1.1e-117 393.1 2.6 1.5e-117 392.6 2.6 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family KCH PF16944.5 EPS33857.1 - 1.9e-100 335.8 4.3 2.4e-100 335.5 4.3 1.1 1 0 0 1 1 1 1 Fungal potassium channel Oxidored_FMN PF00724.20 EPS33858.1 - 4.6e-63 213.6 0.0 5.4e-63 213.3 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 EPS33858.1 - 0.014 14.5 0.4 0.095 11.8 0.0 2.0 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) p450 PF00067.22 EPS33859.1 - 8.4e-75 252.3 0.0 1.1e-74 251.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 WGG PF10273.9 EPS33861.1 - 9.5e-30 103.1 0.2 9.5e-30 103.1 0.2 1.7 2 0 0 2 2 2 1 Pre-rRNA-processing protein TSR2 DASH_Dad2 PF08654.10 EPS33861.1 - 0.25 11.8 1.7 0.27 11.7 0.2 1.8 2 0 0 2 2 2 0 DASH complex subunit Dad2 GTP_EFTU PF00009.27 EPS33862.1 - 1.3e-38 132.5 0.0 2.3e-38 131.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EPS33862.1 - 1.2e-27 96.4 0.0 2.4e-27 95.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EPS33862.1 - 4.7e-06 26.9 0.0 1.2e-05 25.6 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EPS33862.1 - 0.043 13.9 0.0 0.14 12.3 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase SRP-alpha_N PF04086.13 EPS33862.1 - 1.8 8.4 12.9 2.8 7.8 12.9 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Trnau1ap PF17654.1 EPS33862.1 - 3.7 8.4 14.7 8.1 7.4 14.7 1.5 1 0 0 1 1 1 0 Selenocysteine tRNA 1 associated proteins TFIIA PF03153.13 EPS33862.1 - 5.4 6.9 16.1 8.4 6.3 16.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ran-binding PF05508.11 EPS33863.1 - 3.8e-122 407.2 0.4 5.2e-122 406.7 0.4 1.2 1 0 0 1 1 1 1 RanGTP-binding protein CSM2 PF16834.5 EPS33863.1 - 0.19 11.3 2.0 0.3 10.7 0.5 1.8 2 0 0 2 2 2 0 Shu complex component Csm2, DNA-binding BSD PF03909.17 EPS33864.1 - 3.3e-19 68.7 1.0 3.3e-19 68.7 1.0 1.9 2 0 0 2 2 2 1 BSD domain Rad4 PF03835.15 EPS33866.1 - 4.3e-35 120.5 1.5 8.9e-35 119.5 0.5 2.1 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 EPS33866.1 - 6.7e-30 103.3 0.1 1.9e-29 101.9 0.1 1.8 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 EPS33866.1 - 4.1e-22 77.7 0.0 1e-21 76.5 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 EPS33866.1 - 2.5e-20 73.2 1.2 2.5e-20 73.2 1.2 2.9 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 EPS33866.1 - 0.089 13.3 0.0 0.47 10.9 0.0 2.3 1 1 0 1 1 1 0 Transglutaminase-like superfamily C8 PF08742.11 EPS33867.1 - 0.013 15.9 0.3 0.094 13.2 0.1 2.0 2 0 0 2 2 2 0 C8 domain Methyltransf_23 PF13489.6 EPS33868.1 - 1.7e-20 73.5 0.0 2.3e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPS33868.1 - 5.9e-10 39.7 0.0 1.2e-09 38.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPS33868.1 - 4.1e-08 33.2 0.0 2.3e-07 30.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS33868.1 - 2.9e-06 27.8 0.0 5.8e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPS33868.1 - 4.8e-06 27.2 0.0 1.6e-05 25.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EPS33868.1 - 0.0007 19.1 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.9 EPS33868.1 - 0.0023 17.7 0.0 0.0036 17.1 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_2 PF00891.18 EPS33868.1 - 0.0073 15.6 0.0 0.011 15.0 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Ubie_methyltran PF01209.18 EPS33868.1 - 0.0079 15.5 0.0 0.037 13.3 0.0 1.9 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EPS33868.1 - 0.015 14.8 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.17 EPS33868.1 - 0.018 14.5 0.0 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Proteasome PF00227.26 EPS33870.1 - 9.4e-45 152.4 0.1 1.2e-44 152.1 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 EPS33870.1 - 1.9e-14 52.8 0.2 1.9e-14 52.8 0.2 1.9 2 0 0 2 2 2 1 Proteasome beta subunits C terminal NUP214 PF16755.5 EPS33871.1 - 1.1e-10 41.4 0.0 1.8e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 ANAPC4_WD40 PF12894.7 EPS33871.1 - 0.0011 19.2 0.0 0.0043 17.3 0.0 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Syntaxin-6_N PF09177.11 EPS33871.1 - 0.018 15.6 1.0 0.031 14.8 0.1 2.0 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Spc7 PF08317.11 EPS33871.1 - 0.055 12.3 0.1 0.055 12.3 0.1 2.3 3 0 0 3 3 3 0 Spc7 kinetochore protein Prefoldin_2 PF01920.20 EPS33871.1 - 0.13 12.3 0.3 6.1 6.9 0.0 2.9 3 0 0 3 3 3 0 Prefoldin subunit Baculo_PEP_C PF04513.12 EPS33871.1 - 0.17 11.9 3.2 1 9.4 3.1 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4407 PF14362.6 EPS33871.1 - 9.3 5.5 9.0 0.55 9.5 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) KH_1 PF00013.29 EPS33873.1 - 1.6e-44 149.6 4.5 1.2e-17 63.4 0.3 3.2 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EPS33873.1 - 2.5e-12 46.5 2.6 0.0049 16.7 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 EPS33873.1 - 4.1e-06 26.6 0.3 0.72 9.8 0.0 3.4 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 EPS33873.1 - 3.5e-05 23.7 0.0 0.01 15.8 0.0 2.7 3 0 0 3 3 3 2 KH-like RNA-binding domain KH_5 PF13184.6 EPS33873.1 - 0.00016 21.7 7.6 0.19 11.8 0.2 3.4 3 0 0 3 3 3 2 NusA-like KH domain Exonuc_VII_L PF02601.15 EPS33874.1 - 0.0043 16.7 0.1 0.0043 16.7 0.1 2.3 1 1 1 2 2 2 1 Exonuclease VII, large subunit TMF_TATA_bd PF12325.8 EPS33874.1 - 0.018 15.2 13.0 0.39 11.0 5.2 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.15 EPS33874.1 - 0.14 12.0 0.3 0.14 12.0 0.3 3.5 2 1 1 3 3 3 0 Septum formation initiator Fib_alpha PF08702.10 EPS33874.1 - 0.2 11.8 7.2 1 9.6 0.4 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family RRF_GI PF12614.8 EPS33874.1 - 0.61 10.3 4.6 6.1 7.0 0.1 3.3 4 0 0 4 4 4 0 Ribosome recycling factor UPF0242 PF06785.11 EPS33874.1 - 0.9 9.6 10.4 1.3 9.0 2.4 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus CENP-K PF11802.8 EPS33874.1 - 1.2 8.6 12.7 2.7 7.5 0.1 3.0 2 1 0 2 2 2 0 Centromere-associated protein K CorA PF01544.18 EPS33874.1 - 8.6 5.6 6.1 12 5.1 0.1 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DEAD PF00270.29 EPS33875.1 - 1.4e-24 86.8 0.0 1.1e-22 80.7 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPS33875.1 - 1.8e-20 73.3 0.0 6.6e-17 61.9 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RQC PF09382.10 EPS33875.1 - 1.8e-16 59.9 0.0 3.5e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 RQC domain RecQ_Zn_bind PF16124.5 EPS33875.1 - 3.4e-16 59.7 7.6 1.1e-15 58.1 7.6 2.0 1 0 0 1 1 1 1 RecQ zinc-binding HRDC PF00570.23 EPS33875.1 - 2.4e-09 37.1 0.0 6.7e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 HRDC domain ResIII PF04851.15 EPS33875.1 - 1.7e-06 28.1 0.0 7.3e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF4110 PF13422.6 EPS33876.1 - 2e-31 107.9 4.0 2e-31 107.9 4.0 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF4110) Kelch_3 PF13415.6 EPS33876.1 - 9.9e-29 99.1 14.7 1e-09 38.4 0.1 7.0 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_4 PF13418.6 EPS33876.1 - 1.7e-25 88.8 15.3 3.4e-07 30.2 0.0 6.3 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.6 EPS33876.1 - 2.5e-16 59.3 4.9 1.1e-05 25.3 0.0 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 EPS33876.1 - 6.5e-15 54.4 9.3 1.9e-05 24.4 0.0 6.1 6 1 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 EPS33876.1 - 7.2e-15 54.7 6.6 0.0025 18.0 0.3 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_1 PF01344.25 EPS33876.1 - 5.5e-13 48.3 1.1 3.5e-05 23.3 0.0 4.8 4 1 0 4 4 4 3 Kelch motif Pyridoxal_deC PF00282.19 EPS33877.1 - 5.7e-25 87.8 0.0 9.2e-25 87.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.21 EPS33877.1 - 0.00013 21.3 0.0 0.0002 20.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EPS33877.1 - 0.004 16.5 0.0 0.0063 15.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EPS33877.1 - 0.022 13.7 0.0 0.038 12.9 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Abhydrolase_1 PF00561.20 EPS33878.1 - 1e-15 58.1 0.0 2e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EPS33878.1 - 2.5e-07 30.2 0.0 4.5e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EPS33878.1 - 1.7e-05 25.6 0.0 2.5e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Mon1 PF03164.14 EPS33879.1 - 2e-153 511.3 0.0 2.3e-153 511.0 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Dopey_N PF04118.14 EPS33880.1 - 6.2e-120 399.9 0.7 2.3e-118 394.8 0.0 2.9 3 1 0 3 3 3 2 Dopey, N-terminal zf-HIT PF04438.16 EPS33882.1 - 6.6e-08 32.3 13.5 1.1e-07 31.6 13.5 1.3 1 0 0 1 1 1 1 HIT zinc finger CCDC53 PF10152.9 EPS33882.1 - 3.9 7.9 6.4 6.3 7.2 6.4 1.4 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex MBOAT PF03062.19 EPS33883.1 - 1.2e-42 146.6 16.0 4.6e-41 141.3 16.0 2.3 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family His_Phos_2 PF00328.22 EPS33884.1 - 0.0022 17.4 0.4 0.02 14.3 0.0 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) Oxidored_molyb PF00174.19 EPS33885.1 - 3.4e-47 160.2 0.0 7.3e-47 159.2 0.0 1.5 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EPS33885.1 - 1.9e-20 73.3 4.7 3.7e-20 72.3 4.7 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Acylphosphatase PF00708.18 EPS33886.1 - 2e-20 73.0 1.8 1.8e-11 44.3 0.1 2.0 1 1 1 2 2 2 2 Acylphosphatase BLUF PF04940.12 EPS33886.1 - 0.028 14.5 0.0 0.039 14.1 0.0 1.2 1 0 0 1 1 1 0 Sensors of blue-light using FAD AOX PF01786.17 EPS33887.1 - 3.7e-100 333.9 0.1 4.5e-100 333.6 0.1 1.1 1 0 0 1 1 1 1 Alternative oxidase CH PF00307.31 EPS33888.1 - 0.04 14.1 0.3 0.16 12.2 0.0 2.1 3 0 0 3 3 3 0 Calponin homology (CH) domain S-antigen PF05756.11 EPS33888.1 - 0.18 12.2 0.0 0.44 10.9 0.0 1.6 1 0 0 1 1 1 0 S-antigen protein KAR9 PF08580.10 EPS33889.1 - 1.7e-218 727.6 2.2 1.7e-218 727.6 2.2 2.1 2 1 1 3 3 3 1 Yeast cortical protein KAR9 Prefoldin PF02996.17 EPS33889.1 - 0.45 10.4 1.5 3.1 7.8 0.1 3.0 2 1 0 2 2 2 0 Prefoldin subunit Acetyltransf_1 PF00583.25 EPS33890.1 - 1.3e-07 31.8 0.1 1.8e-07 31.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 EPS33890.1 - 1e-06 29.4 0.1 2.2e-06 28.4 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EPS33890.1 - 0.00015 22.1 0.0 0.00028 21.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EPS33890.1 - 0.00035 20.7 0.0 0.00051 20.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPS33890.1 - 0.0053 16.7 0.0 0.0099 15.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 EPS33890.1 - 0.019 14.9 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Complex1_LYR_2 PF13233.6 EPS33891.1 - 1e-18 67.8 0.1 1.5e-18 67.3 0.1 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 EPS33891.1 - 2.2e-08 34.0 0.1 3.6e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) MTS PF05175.14 EPS33892.1 - 0.021 14.4 0.1 0.86 9.1 0.1 2.3 1 1 0 1 1 1 0 Methyltransferase small domain LSM PF01423.22 EPS33893.1 - 1.6e-17 62.9 0.0 2e-17 62.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EPS33893.1 - 0.0047 17.0 0.0 0.0061 16.7 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain PRR20 PF15708.5 EPS33893.1 - 2.9 7.8 8.6 3.8 7.4 8.6 1.2 1 0 0 1 1 1 0 Proline-rich protein family 20 API5 PF05918.11 EPS33893.1 - 8.3 5.1 8.8 10 4.8 8.8 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) zf-C2H2 PF00096.26 EPS33894.1 - 6.9e-05 23.1 0.8 0.22 12.0 0.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPS33894.1 - 0.0011 19.6 0.4 2 9.5 0.0 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger GTP_EFTU PF00009.27 EPS33895.1 - 1.3e-08 34.7 0.0 2.1e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EPS33895.1 - 0.007 16.3 0.3 3.5 7.5 0.2 2.3 2 0 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 EPS33895.1 - 0.049 13.4 0.2 2.4 7.9 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PRK PF00485.18 EPS33895.1 - 0.57 9.9 1.4 0.77 9.5 0.3 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AD PF09793.9 EPS33896.1 - 5.9e-28 96.8 0.0 8.3e-28 96.4 0.0 1.2 1 0 0 1 1 1 1 Anticodon-binding domain 6PGD PF00393.19 EPS33897.1 - 3.1e-127 423.9 0.0 3.8e-127 423.6 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EPS33897.1 - 2.4e-51 174.0 0.0 3.5e-51 173.5 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EPS33897.1 - 0.057 13.7 0.0 0.17 12.1 0.0 1.8 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 EPS33897.1 - 0.067 13.8 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 EPS33897.1 - 0.21 11.0 0.0 0.4 10.0 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Coprogen_oxidas PF01218.18 EPS33898.1 - 0.033 12.9 0.2 0.038 12.7 0.2 1.0 1 0 0 1 1 1 0 Coproporphyrinogen III oxidase RRM_1 PF00076.22 EPS33899.1 - 2.1e-16 59.5 0.0 3.3e-16 58.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fungal_trans PF04082.18 EPS33900.1 - 1.5e-11 43.8 0.2 2.4e-11 43.2 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS33900.1 - 8.5e-09 35.4 6.3 2e-08 34.2 6.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2834 PF11196.8 EPS33901.1 - 1.6e-07 31.6 20.1 0.015 15.6 12.7 3.7 2 2 0 2 2 2 2 Protein of unknown function (DUF2834) DHHC PF01529.20 EPS33901.1 - 0.51 10.4 6.6 7.9 6.6 0.3 3.1 2 2 1 3 3 3 0 DHHC palmitoyltransferase ACT_3 PF10000.9 EPS33902.1 - 4.9e-20 71.2 0.2 8.4e-20 70.5 0.2 1.4 1 0 0 1 1 1 1 ACT domain ACT_7 PF13840.6 EPS33902.1 - 1.8e-08 34.0 0.0 3.3e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 ACT domain zf_ZIC PF18366.1 EPS33903.1 - 0.00025 21.1 0.1 0.00065 19.7 0.1 1.7 1 0 0 1 1 1 1 Zic proteins zinc finger domain RFX_DNA_binding PF02257.15 EPS33903.1 - 0.02 15.5 0.0 0.042 14.5 0.0 1.5 1 0 0 1 1 1 0 RFX DNA-binding domain Arm PF00514.23 EPS33903.1 - 0.23 11.6 1.2 1 9.5 0.1 2.6 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Zn_clus PF00172.18 EPS33905.1 - 2.9e-10 40.1 8.2 4.6e-10 39.5 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Copper-fist PF00649.18 EPS33907.1 - 1.3e-21 75.8 3.1 1.3e-21 75.8 3.1 2.4 2 1 1 3 3 3 1 Copper fist DNA binding domain Aminotran_1_2 PF00155.21 EPS33908.1 - 5.7e-39 134.3 0.0 8.3e-39 133.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EPS33908.1 - 0.012 14.2 0.1 0.018 13.6 0.1 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Spherulin4 PF12138.8 EPS33908.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Spherulation-specific family 4 RPN7 PF10602.9 EPS33909.1 - 1.1e-51 175.0 0.4 1.9e-51 174.2 0.1 1.6 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 EPS33909.1 - 7.2e-16 58.6 0.0 1.3e-15 57.7 0.0 1.5 1 0 0 1 1 1 1 PCI domain Sugar_tr PF00083.24 EPS33911.1 - 3.3e-30 105.3 21.7 1.2e-19 70.6 8.3 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EPS33911.1 - 9.3e-16 57.7 37.4 5.3e-10 38.8 19.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PDR_CDR PF06422.12 EPS33911.1 - 2 8.4 4.5 3.1 7.8 0.2 3.1 3 0 0 3 3 3 0 CDR ABC transporter PEX11 PF05648.14 EPS33912.1 - 1.9e-72 243.3 0.3 2.2e-72 243.2 0.3 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) TBPIP PF07106.13 EPS33912.1 - 0.075 13.0 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 TBPIP/Hop2 winged helix domain Arch_fla_DE PF04659.13 EPS33912.1 - 0.088 12.7 0.1 0.2 11.5 0.1 1.6 1 0 0 1 1 1 0 Archaeal flagella protein PEPCK_ATP PF01293.20 EPS33916.1 - 1.9e-217 722.5 0.0 2.2e-217 722.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_25 PF13481.6 EPS33916.1 - 0.081 12.5 0.0 5 6.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EPS33916.1 - 0.16 12.2 0.0 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mito_carr PF00153.27 EPS33917.1 - 2.2e-55 184.6 4.0 2.9e-18 65.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.16 EPS33918.1 - 1.1e-09 37.8 34.6 2.1e-09 36.8 34.5 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.16 EPS33918.1 - 4.1e-08 33.1 6.6 4.1e-08 33.1 6.6 2.7 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 zf-Nse PF11789.8 EPS33919.1 - 6e-20 70.8 0.5 1e-19 70.0 0.5 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EPS33919.1 - 2.5e-05 24.2 0.0 6.4e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EPS33919.1 - 0.0022 17.8 0.5 0.017 15.0 0.0 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 EPS33919.1 - 0.0028 17.8 0.0 0.0069 16.5 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-C3HC4 PF00097.25 EPS33919.1 - 0.0054 16.6 0.1 0.0099 15.7 0.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FAM216B PF15107.6 EPS33919.1 - 0.0058 16.5 0.3 0.015 15.1 0.3 1.7 1 0 0 1 1 1 1 FAM216B protein family zf-RING_2 PF13639.6 EPS33919.1 - 0.014 15.7 0.1 0.025 14.9 0.1 1.4 1 0 0 1 1 1 0 Ring finger domain zf-ribbon_3 PF13248.6 EPS33919.1 - 0.044 13.2 0.2 0.11 11.9 0.1 1.8 2 0 0 2 2 2 0 zinc-ribbon domain DNA_ligase_ZBD PF03119.16 EPS33919.1 - 0.074 13.1 0.0 0.25 11.4 0.0 2.0 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain zf-MIZ PF02891.20 EPS33919.1 - 0.15 11.9 1.8 0.51 10.1 1.8 1.9 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger zf-NOSIP PF15906.5 EPS33919.1 - 0.18 12.0 0.0 0.41 10.8 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein TMPIT PF07851.13 EPS33919.1 - 2.1 7.5 4.8 3.3 6.9 4.8 1.2 1 0 0 1 1 1 0 TMPIT-like protein Pox_MCEL PF03291.16 EPS33920.1 - 2.6e-66 224.0 0.0 2.1e-63 214.5 0.0 3.3 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 EPS33920.1 - 1.3e-08 35.5 0.0 0.0042 17.7 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 EPS33920.1 - 9.4e-08 32.7 0.0 0.002 18.8 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 EPS33920.1 - 5.3e-07 30.2 0.0 0.014 16.0 0.0 2.8 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.6 EPS33920.1 - 2.9e-06 27.2 0.0 5.2e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPS33920.1 - 4.8e-05 23.2 0.0 0.0021 17.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 EPS33920.1 - 0.011 14.9 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Methyltransf_9 PF08003.11 EPS33920.1 - 0.068 12.1 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) zf-C3HC PF07967.13 EPS33922.1 - 9.1e-44 148.7 0.6 1.1e-38 132.3 0.1 2.4 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.10 EPS33922.1 - 1.6e-33 114.7 1.4 4.3e-31 106.9 0.0 3.1 3 0 0 3 3 3 2 Rsm1-like BIR PF00653.21 EPS33922.1 - 0.0027 18.3 0.2 3.9 8.2 0.0 2.6 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain COX15-CtaA PF02628.15 EPS33923.1 - 1.2e-114 382.8 4.1 1.4e-114 382.5 4.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein PQ-loop PF04193.14 EPS33923.1 - 0.22 11.3 1.2 11 5.9 0.1 2.8 2 0 0 2 2 2 0 PQ loop repeat C1_2 PF03107.16 EPS33924.1 - 0.9 9.9 7.6 1.6 9.1 7.6 1.4 1 0 0 1 1 1 0 C1 domain tRNA-synt_2 PF00152.20 EPS33925.1 - 6.5e-81 271.8 0.4 1e-80 271.2 0.4 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EPS33925.1 - 1.9e-13 50.2 0.0 5.2e-13 48.8 0.0 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EPS33925.1 - 1.2e-05 25.0 0.1 0.021 14.3 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Dynamin_M PF01031.20 EPS33926.1 - 3.9e-33 114.9 0.0 1.2e-23 83.7 0.0 2.2 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.23 EPS33926.1 - 9e-25 87.7 0.0 4.5e-24 85.4 0.0 2.2 1 1 0 1 1 1 1 Dynamin family GED PF02212.18 EPS33926.1 - 1.1e-05 25.4 0.1 4.2e-05 23.6 0.1 2.0 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EPS33926.1 - 0.0021 18.1 0.1 0.027 14.5 0.0 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 EPS33926.1 - 0.003 17.7 0.2 0.28 11.4 0.0 3.4 4 0 0 4 4 4 1 Ras of Complex, Roc, domain of DAPkinase IIGP PF05049.13 EPS33926.1 - 0.052 12.6 0.1 6.1 5.8 0.0 2.5 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_16 PF13191.6 EPS33926.1 - 0.089 13.2 0.1 0.55 10.6 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain AAA_15 PF13175.6 EPS33926.1 - 0.13 11.9 0.9 2 8.0 0.2 2.2 2 0 0 2 2 2 0 AAA ATPase domain NTP_transferase PF00483.23 EPS33927.1 - 1.8e-31 109.6 0.0 2.5e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 EPS33927.1 - 1.5e-10 40.4 5.3 7.5e-06 25.5 0.2 3.5 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EPS33927.1 - 2.3e-08 34.6 0.0 3.6e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.19 EPS33927.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DUF4954 PF16314.5 EPS33927.1 - 0.083 11.0 0.1 0.24 9.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 EPS33927.1 - 0.35 10.7 2.4 1.2 8.9 0.1 2.9 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase MARVEL PF01284.23 EPS33928.1 - 0.085 12.9 16.9 0.1 12.6 16.9 1.1 1 0 0 1 1 1 0 Membrane-associating domain DUF2070 PF09843.9 EPS33928.1 - 1.1 7.4 13.5 1.5 7.0 13.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Dynamin_N PF00350.23 EPS33929.1 - 3.7e-16 59.6 0.0 3.1e-15 56.6 0.0 2.6 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 EPS33929.1 - 3.3e-06 27.2 0.1 0.00011 22.2 0.1 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EPS33929.1 - 0.00013 22.5 0.0 0.0012 19.3 0.0 2.7 2 0 0 2 2 2 1 ABC transporter AIG1 PF04548.16 EPS33929.1 - 0.00074 18.9 1.9 0.002 17.5 0.1 2.7 3 0 0 3 3 3 1 AIG1 family AAA_22 PF13401.6 EPS33929.1 - 0.001 19.4 0.1 0.18 12.1 0.0 3.8 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 EPS33929.1 - 0.0016 18.4 5.3 0.0021 18.0 0.0 3.7 5 1 0 5 5 5 1 RsgA GTPase IIGP PF05049.13 EPS33929.1 - 0.011 14.9 0.0 0.11 11.5 0.0 2.3 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) NB-ARC PF00931.22 EPS33929.1 - 0.05 12.8 0.1 0.13 11.4 0.1 1.7 1 0 0 1 1 1 0 NB-ARC domain AAA_29 PF13555.6 EPS33929.1 - 0.25 11.1 1.3 1.1 9.0 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EPS33929.1 - 0.86 10.0 6.7 0.13 12.7 0.3 2.9 2 2 0 2 2 2 0 AAA ATPase domain Chlorophyllase2 PF12740.7 EPS33930.1 - 2e-08 33.4 0.0 3.2e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme PAF-AH_p_II PF03403.13 EPS33930.1 - 4e-07 28.9 0.0 0.012 14.1 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.7 EPS33930.1 - 5.8e-07 30.3 3.5 8.2e-07 29.8 3.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.11 EPS33930.1 - 7.7e-07 28.4 0.1 1.5e-06 27.5 0.1 1.4 1 1 0 1 1 1 1 Chlorophyllase Hydrolase_4 PF12146.8 EPS33930.1 - 0.014 14.7 0.0 0.038 13.3 0.0 1.8 2 1 0 2 2 2 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EPS33930.1 - 0.042 13.3 0.0 0.098 12.1 0.0 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family FSH1 PF03959.13 EPS33930.1 - 0.21 11.2 0.0 0.31 10.7 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) zf-RING_2 PF13639.6 EPS33931.1 - 2.2e-08 34.3 2.3 3.3e-08 33.7 2.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EPS33931.1 - 7.2e-06 26.2 2.5 0.00012 22.3 2.6 2.2 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EPS33931.1 - 0.00074 19.5 0.4 0.0011 18.9 0.4 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EPS33931.1 - 0.00086 19.3 5.6 0.0015 18.5 5.6 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 EPS33931.1 - 0.0072 16.1 1.4 0.013 15.3 1.4 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EPS33931.1 - 0.0084 15.9 3.4 0.062 13.2 3.4 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_9 PF14369.6 EPS33931.1 - 0.055 13.7 0.2 0.13 12.6 0.2 1.7 1 0 0 1 1 1 0 zinc-ribbon zf-C3HC4_3 PF13920.6 EPS33931.1 - 0.065 13.1 1.0 0.44 10.4 1.2 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPS33931.1 - 0.15 11.9 0.6 0.31 10.9 0.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DHHC PF01529.20 EPS33932.1 - 1.2e-32 112.8 7.4 3.2e-32 111.4 7.4 1.8 1 0 0 1 1 1 1 DHHC palmitoyltransferase Atx10homo_assoc PF09759.9 EPS33932.1 - 1.1e-31 108.8 0.3 2.5e-31 107.6 0.1 1.8 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain RNA_pol_3_Rpc31 PF11705.8 EPS33932.1 - 2.2 8.4 13.9 4.7 7.4 13.9 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Astro_capsid_p PF12226.8 EPS33932.1 - 3.2 6.8 11.5 5.1 6.2 11.5 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Rap1_C PF11626.8 EPS33933.1 - 3.3e-22 78.4 0.0 7.6e-22 77.2 0.0 1.6 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.11 EPS33933.1 - 5.3e-17 61.8 0.1 1.3e-16 60.6 0.1 1.7 1 0 0 1 1 1 1 Rap1 Myb domain BRCT_2 PF16589.5 EPS33933.1 - 6.8e-12 45.6 0.0 1.4e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain Rap1-DNA-bind PF09197.10 EPS33933.1 - 0.015 15.9 0.0 0.031 14.9 0.0 1.5 1 0 0 1 1 1 0 Rap1, DNA-binding Chromo_shadow PF01393.19 EPS33934.1 - 4.2e-16 58.8 0.5 5.6e-13 48.8 0.0 2.4 2 0 0 2 2 2 2 Chromo shadow domain Chromo PF00385.24 EPS33934.1 - 3.7e-12 46.0 1.6 1e-11 44.6 1.2 2.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Cpn60_TCP1 PF00118.24 EPS33935.1 - 1.8e-155 518.3 4.4 2.1e-155 518.1 4.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3295 PF11702.8 EPS33938.1 - 3.8e-190 633.5 25.4 4.4e-190 633.3 25.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.10 EPS33938.1 - 2.7e-12 46.3 1.9 6.2e-12 45.1 1.9 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Con-6 PF10346.9 EPS33938.1 - 0.013 15.5 0.1 0.028 14.5 0.1 1.6 1 0 0 1 1 1 0 Conidiation protein 6 TFIIA PF03153.13 EPS33938.1 - 5.3 6.9 15.4 0.15 12.0 7.4 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit FRG PF08867.11 EPS33940.1 - 0.11 13.5 0.1 0.2 12.6 0.0 1.5 2 0 0 2 2 2 0 FRG domain zf-CHY PF05495.12 EPS33941.1 - 6.8e-12 45.7 8.7 6.8e-12 45.7 8.7 3.4 2 1 0 3 3 3 1 CHY zinc finger CENP-B_dimeris PF09026.10 EPS33941.1 - 1.9 8.9 8.3 0.079 13.4 2.2 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Glyoxalase PF00903.25 EPS33942.1 - 5.3e-22 78.4 1.1 1.2e-15 57.8 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EPS33942.1 - 4.4e-13 49.4 0.1 1.5e-05 25.2 0.0 2.6 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EPS33942.1 - 5.6e-09 36.4 0.2 0.00012 22.3 0.2 2.7 2 1 1 3 3 3 2 Glyoxalase-like domain Glyoxalase_5 PF14696.6 EPS33942.1 - 2.7e-07 30.8 0.4 7.8e-06 26.1 0.2 2.5 2 1 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal DUF4844 PF16133.5 EPS33942.1 - 0.035 14.7 0.1 0.12 12.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4844) TPR_17 PF13431.6 EPS33943.1 - 0.0011 19.2 0.2 0.033 14.6 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat HgmA PF04209.13 EPS33944.1 - 4.5e-209 694.4 0.3 5.1e-209 694.3 0.3 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase FAA_hydrolase PF01557.18 EPS33945.1 - 3.6e-54 183.7 0.0 4.8e-54 183.3 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 EPS33945.1 - 1.8e-31 108.5 0.0 4.5e-31 107.2 0.1 1.6 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal DUF863 PF05904.11 EPS33945.1 - 0.29 9.5 0.1 0.62 8.4 0.0 1.5 2 0 0 2 2 2 0 Plant protein of unknown function (DUF863) GST_N PF02798.20 EPS33946.1 - 1.7e-10 41.1 0.0 2.8e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EPS33946.1 - 3.1e-10 40.3 0.0 5e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EPS33946.1 - 4.1e-10 39.8 0.0 9.3e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EPS33946.1 - 1.1e-06 28.7 0.0 2.8e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EPS33946.1 - 1.7e-05 24.9 0.0 3.7e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EPS33946.1 - 0.00036 20.5 0.0 0.00072 19.5 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain B5 PF03484.15 EPS33946.1 - 0.17 12.2 0.0 33 4.9 0.0 3.0 3 0 0 3 3 3 0 tRNA synthetase B5 domain Zn_clus PF00172.18 EPS33947.1 - 8.2e-07 29.0 5.9 1.4e-06 28.3 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tim17 PF02466.19 EPS33948.1 - 4.1e-33 114.1 8.9 5.2e-33 113.7 8.9 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HATPase_c_4 PF13749.6 EPS33948.1 - 0.029 14.5 0.0 0.039 14.1 0.0 1.3 1 1 0 1 1 1 0 Putative ATP-dependent DNA helicase recG C-terminal PsaL PF02605.15 EPS33948.1 - 0.92 9.2 5.2 9.2 5.9 0.1 2.3 2 0 0 2 2 2 0 Photosystem I reaction centre subunit XI Asparaginase_2 PF01112.18 EPS33949.1 - 7.9e-60 202.5 0.0 1.9e-51 174.9 0.0 3.2 3 1 0 3 3 3 2 Asparaginase ABC2_membrane PF01061.24 EPS33953.1 - 1.2e-84 282.9 56.3 5.6e-47 159.9 22.8 3.1 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.12 EPS33953.1 - 8.6e-39 131.3 3.1 7.1e-30 102.8 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.27 EPS33953.1 - 2.6e-38 131.6 0.0 2.4e-19 70.2 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.6 EPS33953.1 - 2.8e-12 47.1 0.6 1.4e-11 44.8 0.2 2.5 2 0 0 2 2 2 1 ABC-transporter N-terminal AAA_16 PF13191.6 EPS33953.1 - 2.5e-07 31.3 0.0 0.00036 21.0 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain ABC2_membrane_3 PF12698.7 EPS33953.1 - 5.8e-07 28.9 49.2 1.3e-05 24.4 18.6 3.2 2 1 1 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.6 EPS33953.1 - 7.1e-06 26.0 0.4 0.089 12.6 0.0 2.7 3 0 0 3 3 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EPS33953.1 - 0.0001 22.2 0.2 0.00034 20.6 0.0 1.8 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 EPS33953.1 - 0.00018 22.0 0.0 0.031 14.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 EPS33953.1 - 0.00031 21.2 2.1 0.11 13.0 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 EPS33953.1 - 0.00062 19.5 0.4 0.18 11.6 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EPS33953.1 - 0.0044 17.3 0.3 0.39 11.0 0.2 3.1 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EPS33953.1 - 0.0056 16.8 0.0 0.2 11.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 EPS33953.1 - 0.013 15.1 0.1 0.046 13.3 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.6 EPS33953.1 - 0.014 15.0 0.2 0.049 13.2 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EPS33953.1 - 0.023 14.4 0.2 0.47 10.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EPS33953.1 - 0.043 13.7 0.5 0.48 10.3 0.1 2.4 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 EPS33953.1 - 0.062 13.4 0.4 0.83 9.8 0.1 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.6 EPS33953.1 - 0.065 13.5 0.1 0.065 13.5 0.1 1.8 2 0 0 2 2 1 0 AAA domain CPSF73-100_C PF11718.8 EPS33953.1 - 0.089 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term DUF1040 PF06288.13 EPS33953.1 - 0.16 12.3 0.0 0.36 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1040) FtsK_SpoIIIE PF01580.18 EPS33953.1 - 0.18 11.1 0.3 22 4.3 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family zf-C2HC_2 PF13913.6 EPS33954.1 - 0.039 13.9 0.9 0.084 12.8 0.1 1.9 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.6 EPS33954.1 - 0.06 14.2 0.3 0.16 12.9 0.3 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EPS33954.1 - 0.089 12.6 0.6 0.22 11.3 0.6 1.6 1 0 0 1 1 1 0 zinc-finger C2H2-type zf-C2H2 PF00096.26 EPS33954.1 - 0.12 12.9 0.2 0.28 11.7 0.2 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type Amidase PF01425.21 EPS33955.1 - 8.8e-101 338.1 0.0 1.1e-100 337.7 0.0 1.1 1 0 0 1 1 1 1 Amidase 2OG-FeII_Oxy_2 PF13532.6 EPS33956.1 - 3.6e-30 105.6 0.0 1.5e-29 103.6 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.25 EPS33957.1 - 4.2e-71 239.4 0.0 6e-71 238.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS33957.1 - 1.3e-30 106.6 0.0 1.6e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EPS33957.1 - 6.1e-05 22.5 0.0 0.00012 21.5 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EPS33957.1 - 0.00017 20.7 0.2 0.009 15.0 0.0 2.0 2 0 0 2 2 2 2 Haspin like kinase domain APH PF01636.23 EPS33957.1 - 0.0058 16.6 0.0 0.0087 16.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EPS33957.1 - 0.0087 15.1 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Peptidase_C2 PF00648.21 EPS33958.1 - 1.2e-63 215.0 0.5 5.4e-42 143.8 0.1 2.5 2 0 0 2 2 2 2 Calpain family cysteine protease Abhydrolase_3 PF07859.13 EPS33959.1 - 4.9e-07 29.8 0.2 3.9e-05 23.6 0.2 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EPS33959.1 - 0.0018 18.0 0.1 0.0033 17.1 0.1 1.4 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 EPS33959.1 - 0.017 14.6 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EPS33959.1 - 0.023 14.3 0.0 0.05 13.2 0.0 1.5 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 EPS33959.1 - 0.064 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold BAAT_C PF08840.11 EPS33959.1 - 0.16 11.9 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal FXR_C1 PF16096.5 EPS33959.1 - 0.5 10.6 2.7 0.3 11.3 0.3 1.9 2 0 0 2 2 2 0 Fragile X-related 1 protein C-terminal region 2 Fungal_trans PF04082.18 EPS33960.1 - 1.2e-16 60.6 0.1 2.2e-16 59.7 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS33960.1 - 1.4e-08 34.7 13.1 2.4e-08 34.0 13.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyoxalase PF00903.25 EPS33961.1 - 2.4e-36 124.8 0.1 5.6e-19 68.6 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EPS33961.1 - 1.3e-14 54.4 0.3 8.7e-06 26.0 0.0 3.9 1 1 3 4 4 4 4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EPS33961.1 - 9.7e-06 25.8 0.0 0.11 12.6 0.0 3.0 1 1 1 2 2 2 2 Glyoxalase-like domain Glyoxalase_6 PF18029.1 EPS33961.1 - 5.9e-05 23.8 0.0 0.58 11.0 0.0 2.8 2 2 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_2 PF12681.7 EPS33961.1 - 0.00025 21.0 0.0 5.8 6.9 0.0 3.9 4 0 0 4 4 4 1 Glyoxalase-like domain CppA_N PF14506.6 EPS33961.1 - 0.077 13.1 0.0 0.42 10.7 0.0 2.1 2 0 0 2 2 2 0 CppA N-terminal ATP-synt_D PF01813.17 EPS33964.1 - 0.062 13.1 0.2 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 ATP synthase subunit D SPG48 PF14764.6 EPS33964.1 - 0.92 10.0 2.8 9.6 6.7 1.4 2.8 2 1 0 2 2 2 0 AP-5 complex subunit, vesicle trafficking Golgin_A5 PF09787.9 EPS33964.1 - 3 7.2 7.5 0.49 9.8 3.8 1.5 2 0 0 2 2 2 0 Golgin subfamily A member 5 Arrestin_C PF02752.22 EPS33965.1 - 4.9e-19 69.1 0.1 8.5e-19 68.3 0.1 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EPS33965.1 - 1e-10 41.9 0.0 1.7e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 EPS33965.1 - 0.0031 17.2 0.0 0.0059 16.3 0.0 1.5 1 0 0 1 1 1 1 Arrestin_N terminal like CAP59_mtransfer PF11735.8 EPS33966.1 - 7.2e-50 169.9 0.0 9.3e-50 169.6 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 PRC PF05239.16 EPS33966.1 - 0.03 14.4 0.0 0.066 13.3 0.0 1.5 1 0 0 1 1 1 0 PRC-barrel domain Tail_VII PF17091.5 EPS33967.1 - 0.076 12.9 0.6 0.14 12.1 0.6 1.5 1 0 0 1 1 1 0 Inovirus G7P protein Holin_BhlA PF10960.8 EPS33967.1 - 0.19 11.7 0.2 4.2 7.4 0.0 2.2 2 0 0 2 2 2 0 BhlA holin family DAO PF01266.24 EPS33968.1 - 6.6e-42 144.3 0.0 7.7e-42 144.1 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EPS33968.1 - 1.1e-06 28.8 0.0 2.6e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EPS33968.1 - 7e-06 25.4 0.0 0.053 12.6 0.0 2.5 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.14 EPS33968.1 - 2.5e-05 23.7 0.0 0.031 13.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EPS33968.1 - 2.6e-05 23.5 0.3 0.0052 15.9 0.0 2.3 2 1 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EPS33968.1 - 0.0015 17.8 0.0 0.0023 17.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EPS33968.1 - 0.0019 17.5 0.0 0.011 15.0 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EPS33968.1 - 0.0024 17.8 0.1 2 8.4 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding HI0933_like PF03486.14 EPS33968.1 - 0.021 13.5 0.0 4.4 5.9 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 EPS33968.1 - 0.032 14.8 0.0 0.065 13.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EPS33968.1 - 0.033 13.4 0.0 0.81 8.9 0.0 2.1 2 0 0 2 2 2 0 Thi4 family TrkA_N PF02254.18 EPS33968.1 - 0.047 13.9 0.0 0.092 13.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Glu_dehyd_C PF16912.5 EPS33968.1 - 0.056 12.9 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Shikimate_DH PF01488.20 EPS33968.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Amino_oxidase PF01593.24 EPS33968.1 - 0.12 11.7 0.0 2.5 7.3 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase DUF2235 PF09994.9 EPS33970.1 - 2.1e-76 257.0 0.2 3.3e-76 256.4 0.2 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) CdiI_N PF18228.1 EPS33970.1 - 0.11 12.3 0.9 0.44 10.4 0.9 2.0 1 0 0 1 1 1 0 CdiI N-terminal domain DNA_primase_lrg PF04104.14 EPS33970.1 - 0.2 11.1 1.1 0.24 10.8 0.0 1.5 2 0 0 2 2 2 0 Eukaryotic and archaeal DNA primase, large subunit RTA1 PF04479.13 EPS33974.1 - 1.3e-39 135.9 6.5 2e-39 135.3 6.5 1.3 1 0 0 1 1 1 1 RTA1 like protein MpPF26 PF07666.11 EPS33974.1 - 0.35 11.0 2.6 0.38 10.9 0.2 2.1 2 0 0 2 2 2 0 M penetrans paralogue family 26 Zn_clus PF00172.18 EPS33975.1 - 2.8e-07 30.5 15.3 4.6e-07 29.9 15.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zds_C PF08632.10 EPS33976.1 - 2.4e-27 94.4 1.1 4.3e-27 93.6 1.1 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Ysc84 PF04366.12 EPS33977.1 - 2.1e-40 137.4 1.8 2.1e-40 137.4 0.6 1.6 2 0 0 2 2 2 1 Las17-binding protein actin regulator SH3_1 PF00018.28 EPS33977.1 - 3.9e-14 52.0 0.5 9.7e-14 50.7 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EPS33977.1 - 3.4e-10 39.6 0.0 6.1e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EPS33977.1 - 1e-09 37.9 0.3 2.4e-09 36.7 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain EF_assoc_2 PF08356.12 EPS33978.1 - 1.1e-35 121.4 0.0 2.1e-35 120.6 0.0 1.5 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 EPS33978.1 - 3.1e-31 106.8 0.2 5.2e-31 106.1 0.2 1.4 1 0 0 1 1 1 1 EF hand associated Ras PF00071.22 EPS33978.1 - 1.8e-23 82.9 0.0 2.3e-14 53.3 0.0 2.1 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EPS33978.1 - 4.9e-12 46.1 0.0 2.1e-07 31.2 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EPS33978.1 - 5.8e-10 39.3 0.0 0.00021 21.4 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_1 PF00036.32 EPS33978.1 - 7.8e-06 25.1 0.9 0.11 12.1 0.1 2.6 2 0 0 2 2 2 2 EF hand AAA_29 PF13555.6 EPS33978.1 - 2.3e-05 24.0 0.3 0.017 14.9 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EPS33978.1 - 4.6e-05 23.9 0.0 0.12 12.7 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain EF-hand_6 PF13405.6 EPS33978.1 - 6e-05 22.7 1.0 0.16 12.0 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EPS33978.1 - 6.6e-05 23.3 0.1 0.016 15.7 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair GTP_EFTU PF00009.27 EPS33978.1 - 0.00022 20.9 0.0 1.9 8.0 0.0 3.2 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_28 PF13521.6 EPS33978.1 - 0.00024 21.4 0.1 0.13 12.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 EPS33978.1 - 0.00034 20.7 0.6 0.72 9.9 0.4 2.9 2 1 1 3 3 3 2 Dynamin family AAA_18 PF13238.6 EPS33978.1 - 0.00049 20.7 0.2 1.6 9.3 0.3 2.6 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EPS33978.1 - 0.0005 20.0 0.3 2.3 8.1 0.1 3.4 3 0 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 EPS33978.1 - 0.00051 20.3 0.2 1.6 9.0 0.0 2.8 2 1 1 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 EPS33978.1 - 0.0025 17.6 0.3 0.047 13.4 0.0 2.5 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 EPS33978.1 - 0.0045 17.4 0.0 1 9.7 0.0 2.5 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.12 EPS33978.1 - 0.0079 16.1 0.2 4.3 7.2 0.0 2.6 2 0 0 2 2 2 1 NACHT domain ABC_tran PF00005.27 EPS33978.1 - 0.0083 16.6 0.0 5.7 7.5 0.0 2.5 2 0 0 2 2 2 0 ABC transporter FtsK_SpoIIIE PF01580.18 EPS33978.1 - 0.0087 15.4 0.2 0.74 9.1 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family EF-hand_8 PF13833.6 EPS33978.1 - 0.012 15.5 0.1 0.27 11.1 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain pair AAA_25 PF13481.6 EPS33978.1 - 0.012 15.2 0.1 3.5 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain Arf PF00025.21 EPS33978.1 - 0.012 15.1 0.1 10 5.5 0.0 3.1 3 0 0 3 3 3 0 ADP-ribosylation factor family Ploopntkinase3 PF18751.1 EPS33978.1 - 0.021 14.8 0.0 2.2 8.1 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_33 PF13671.6 EPS33978.1 - 0.025 14.7 0.0 6.9 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EPS33978.1 - 0.031 14.0 0.1 0.41 10.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EPS33978.1 - 0.039 13.5 0.2 1.5 8.3 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Septin PF00735.18 EPS33978.1 - 0.056 12.7 0.0 0.76 9.0 0.0 2.2 2 0 0 2 2 2 0 Septin EF-hand_5 PF13202.6 EPS33978.1 - 0.057 12.9 3.3 5.1 6.8 0.3 2.6 2 0 0 2 2 2 0 EF hand DUF815 PF05673.13 EPS33978.1 - 0.071 12.3 0.3 2.6 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) SMC_N PF02463.19 EPS33978.1 - 0.085 12.3 0.3 2.6 7.4 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_5 PF07728.14 EPS33978.1 - 0.094 12.7 0.2 25 4.9 0.0 2.9 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) IIGP PF05049.13 EPS33978.1 - 0.1 11.6 0.5 1.7 7.6 0.1 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA PF00004.29 EPS33978.1 - 0.12 12.8 0.5 15 6.1 0.0 3.1 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) MCM PF00493.23 EPS33978.1 - 0.17 10.9 0.0 3.2 6.8 0.0 2.2 2 0 0 2 2 2 0 MCM P-loop domain ATP_bind_1 PF03029.17 EPS33978.1 - 0.22 11.3 1.5 47 3.7 0.0 3.4 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein cobW PF02492.19 EPS33978.1 - 0.33 10.5 1.8 8.3 6.0 0.1 3.5 4 1 0 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain ANAPC4_WD40 PF12894.7 EPS33979.1 - 2.3e-09 37.4 0.0 0.013 15.8 0.0 3.4 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EPS33979.1 - 2.9e-07 31.1 17.0 0.00033 21.4 0.7 5.5 5 1 0 5 5 5 3 WD domain, G-beta repeat IKI3 PF04762.12 EPS33979.1 - 0.00087 17.4 0.0 0.041 11.9 0.0 2.0 1 1 1 2 2 2 2 IKI3 family Cytochrom_D1 PF02239.16 EPS33979.1 - 0.0033 16.0 0.0 0.006 15.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain eIF2A PF08662.11 EPS33979.1 - 0.019 14.9 0.0 1.7 8.5 0.0 2.2 1 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Pkinase PF00069.25 EPS33981.1 - 8.1e-23 81.1 0.0 7.3e-22 78.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS33981.1 - 1.5e-07 31.0 0.0 1.1e-05 24.8 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EPS33981.1 - 0.085 12.8 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family AAA_22 PF13401.6 EPS33982.1 - 0.00054 20.3 0.2 1.4 9.2 0.0 2.6 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EPS33982.1 - 0.0098 16.3 0.0 3 8.2 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain Adeno_IVa2 PF02456.15 EPS33982.1 - 0.016 14.0 0.0 0.026 13.3 0.0 1.3 1 0 0 1 1 1 0 Adenovirus IVa2 protein Zot PF05707.12 EPS33982.1 - 0.032 13.9 0.0 0.12 12.0 0.0 1.9 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) FtsK_SpoIIIE PF01580.18 EPS33982.1 - 0.052 12.9 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family GPI-anchored PF10342.9 EPS33983.1 - 4.2e-18 65.9 1.1 7.5e-18 65.1 1.1 1.4 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CUE PF02845.16 EPS33984.1 - 4.8e-12 45.3 0.3 1.8e-08 33.9 0.0 3.2 3 0 0 3 3 3 2 CUE domain Smr PF01713.21 EPS33984.1 - 0.001 19.4 0.2 0.0023 18.2 0.2 1.6 1 0 0 1 1 1 1 Smr domain SelR PF01641.18 EPS33985.1 - 5e-50 168.6 0.1 6.7e-50 168.2 0.1 1.2 1 0 0 1 1 1 1 SelR domain DZR PF12773.7 EPS33985.1 - 0.042 13.9 0.3 7.1 6.7 0.0 2.3 2 0 0 2 2 2 0 Double zinc ribbon zinc_ribbon_10 PF10058.9 EPS33985.1 - 0.052 13.3 0.1 0.51 10.1 0.0 2.1 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein MCM_OB PF17207.3 EPS33985.1 - 0.11 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 MCM OB domain TF_Zn_Ribbon PF08271.12 EPS33985.1 - 0.21 11.1 1.0 0.92 9.1 0.2 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding ArfGap PF01412.18 EPS33986.1 - 2e-39 134.3 1.4 2.9e-39 133.8 1.4 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Tad PF13400.6 EPS33989.1 - 0.08 13.3 2.6 0.094 13.0 2.6 1.1 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like Sigma_reg_N PF13800.6 EPS33989.1 - 0.12 12.7 0.3 0.14 12.5 0.3 1.2 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF4342 PF14242.6 EPS33989.1 - 0.13 12.2 2.5 0.16 12.0 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4342) Iron_permease PF04120.12 EPS33989.1 - 0.14 11.9 0.3 0.16 11.7 0.3 1.1 1 0 0 1 1 1 0 Low affinity iron permease Prominin PF05478.11 EPS33989.1 - 0.33 8.9 0.5 0.33 8.8 0.5 1.0 1 0 0 1 1 1 0 Prominin Med13_C PF06333.12 EPS33990.1 - 4.1e-85 285.9 2.0 4.1e-85 285.9 2.0 2.5 3 0 0 3 3 3 1 Mediator complex subunit 13 C-terminal domain Med13_N PF11597.8 EPS33990.1 - 1.1e-74 251.7 0.0 1.8e-74 250.9 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal MID_MedPIWI PF18296.1 EPS33990.1 - 1.3e-32 113.6 0.2 9.9e-30 104.1 0.2 2.8 1 1 0 1 1 1 1 MID domain of medPIWI Rsm1 PF08600.10 EPS33990.1 - 0.037 14.2 0.0 0.097 12.8 0.0 1.7 1 0 0 1 1 1 0 Rsm1-like NUC153 PF08159.12 EPS33991.1 - 8e-11 41.6 2.9 2e-10 40.3 2.9 1.8 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 EPS33991.1 - 0.002 18.9 0.0 93 4.1 0.0 4.6 5 0 0 5 5 5 0 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS33991.1 - 0.042 14.1 0.0 0.2 12.0 0.0 2.1 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain ATG13 PF10033.9 EPS33992.1 - 1.2e-70 237.9 0.0 1.8e-70 237.4 0.0 1.3 1 0 0 1 1 1 1 Autophagy-related protein 13 p450 PF00067.22 EPS33994.1 - 4.5e-29 101.5 0.0 5.8e-29 101.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HRG PF16954.5 EPS33994.1 - 1.1 9.7 0.0 1.1 9.7 0.0 2.8 3 0 0 3 3 3 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene LIP PF03583.14 EPS33995.1 - 2.4e-62 210.8 0.1 3.5e-62 210.3 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.21 EPS33995.1 - 0.00068 19.2 0.1 0.019 14.4 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 EPS33995.1 - 0.0038 16.8 0.0 0.0075 15.8 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 EPS33995.1 - 0.016 15.1 0.0 0.036 13.9 0.0 1.6 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 EPS33995.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold TraW_N PF12477.8 EPS33995.1 - 1.8 8.6 4.2 6.7 6.8 0.3 3.1 3 0 0 3 3 3 0 Sex factor F TraW protein N terminal RCC1 PF00415.18 EPS33996.1 - 7.6e-22 77.7 1.1 1.2e-05 25.8 0.0 6.4 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 EPS33996.1 - 2.9e-12 46.8 0.1 4.8e-08 33.2 0.0 2.8 2 0 0 2 2 2 2 BTB/POZ domain RCC1_2 PF13540.6 EPS33996.1 - 4.5e-11 42.2 7.4 6.3e-08 32.2 0.1 3.6 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.6 EPS33996.1 - 7.4e-07 29.6 0.5 5.9e-06 26.7 0.1 2.6 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPS33996.1 - 0.00062 20.0 0.4 2.5 9.0 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EPS33996.1 - 0.0033 18.0 0.1 0.0078 16.8 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EPS33996.1 - 0.041 14.2 0.1 0.82 10.1 0.1 3.0 3 0 0 3 3 3 0 Ankyrin repeats (many copies) TCO89 PF10452.9 EPS33997.1 - 0.00012 21.2 0.1 0.011 14.7 0.0 3.6 3 1 0 3 3 3 2 TORC1 subunit TCO89 VHS PF00790.19 EPS33998.1 - 1.9e-40 138.0 0.8 3.4e-39 133.9 0.0 2.3 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 EPS33998.1 - 3.3e-16 59.2 1.4 5.4e-16 58.5 1.4 1.3 1 0 0 1 1 1 1 FYVE zinc finger GAT PF03127.14 EPS33998.1 - 5.7e-06 26.5 0.3 0.0001 22.6 0.0 2.6 2 0 0 2 2 2 1 GAT domain UIM PF02809.20 EPS33998.1 - 8.9e-06 25.3 15.6 0.0023 17.8 3.0 3.3 3 0 0 3 3 3 2 Ubiquitin interaction motif FYVE_2 PF02318.16 EPS33998.1 - 0.02 15.1 0.1 0.041 14.1 0.1 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger Npa1 PF11707.8 EPS33998.1 - 0.04 13.3 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 Ribosome 60S biogenesis N-terminal C1_1 PF00130.22 EPS33998.1 - 0.05 13.5 2.8 0.097 12.6 2.8 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF753 PF05444.12 EPS33998.1 - 0.05 13.6 0.7 0.082 12.9 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF753) OST-HTH PF12872.7 EPS33998.1 - 0.12 12.2 0.0 0.34 10.7 0.0 1.8 1 0 0 1 1 1 0 OST-HTH/LOTUS domain DZR PF12773.7 EPS33998.1 - 0.32 11.1 2.5 0.64 10.1 2.5 1.4 1 0 0 1 1 1 0 Double zinc ribbon Fer4_2 PF12797.7 EPS33998.1 - 3.2 8.0 4.1 2.2 8.5 0.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain UCH PF00443.29 EPS33999.1 - 7.2e-52 176.4 0.0 1.1e-51 175.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EPS33999.1 - 4.4e-16 59.4 0.3 2.2e-13 50.5 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.11 EPS33999.1 - 0.00014 22.0 0.1 0.00046 20.4 0.1 1.8 1 0 0 1 1 1 1 USP8 dimerisation domain Rhodanese PF00581.20 EPS33999.1 - 0.0031 18.0 0.0 0.0081 16.7 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Cyt-b5 PF00173.28 EPS34000.1 - 2.1e-22 79.0 0.1 2.8e-22 78.7 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BTB PF00651.31 EPS34001.1 - 3.4e-07 30.5 0.0 5.8e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 EPS34002.1 - 4e-11 43.1 0.0 7.4e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain MafB19-deam PF14437.6 EPS34003.1 - 4.1e-10 39.6 0.0 4.4e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 EPS34003.1 - 1.7e-08 34.3 0.0 2.1e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region SNAD4 PF18750.1 EPS34003.1 - 0.033 14.3 0.0 0.052 13.7 0.0 1.2 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 Bd3614-deam PF14439.6 EPS34003.1 - 0.036 14.1 0.2 4 7.5 0.3 2.2 1 1 1 2 2 2 0 Bd3614-like deaminase NAD2 PF18782.1 EPS34003.1 - 0.043 13.9 0.0 0.062 13.4 0.0 1.2 1 0 0 1 1 1 0 Novel AID APOBEC clade 2 Pyr_redox_2 PF07992.14 EPS34004.1 - 1.3e-12 47.6 0.1 8.2e-10 38.4 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EPS34004.1 - 0.0044 17.0 0.0 0.13 12.3 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 EPS34004.1 - 0.011 15.4 0.1 0.026 14.1 0.1 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase Lactamase_B PF00753.27 EPS34006.1 - 1.2e-15 58.0 1.5 2.7e-15 56.9 1.5 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EPS34006.1 - 0.002 17.7 0.0 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF202 PF02656.15 EPS34007.1 - 1.2e-12 48.1 3.0 1.2e-12 48.1 3.0 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF202) KH_1 PF00013.29 EPS34008.1 - 2.9e-93 305.7 18.4 2.2e-12 46.6 0.1 13.7 14 1 0 14 14 14 9 KH domain KH_2 PF07650.17 EPS34008.1 - 3.6e-13 49.1 21.2 0.0026 17.6 0.3 7.3 6 1 1 7 7 7 6 KH domain SLS PF14611.6 EPS34008.1 - 1.5e-11 44.6 8.8 0.14 11.9 0.0 8.7 6 4 2 8 8 8 4 Mitochondrial inner-membrane-bound regulator KH_4 PF13083.6 EPS34008.1 - 0.00019 21.2 3.9 7.8 6.5 0.0 5.5 5 0 0 5 5 5 2 KH domain KH_5 PF13184.6 EPS34008.1 - 0.31 11.1 10.9 61 3.8 0.2 6.2 7 0 0 7 7 7 0 NusA-like KH domain Transp_cyt_pur PF02133.15 EPS34009.1 - 2e-27 96.1 30.1 3e-27 95.5 30.1 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin SAMP PF05924.11 EPS34009.1 - 0.2 11.0 1.2 0.35 10.2 0.2 2.0 2 0 0 2 2 2 0 SAMP Motif Glyco_hydro_43 PF04616.14 EPS34010.1 - 4e-33 115.0 1.5 5.5e-33 114.5 1.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 SGL PF08450.12 EPS34012.1 - 2.6e-27 96.0 0.0 4e-27 95.4 0.0 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 EPS34012.1 - 2.8e-06 27.4 0.1 1.6e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 Arylesterase Str_synth PF03088.16 EPS34012.1 - 3e-06 27.3 0.0 2.3e-05 24.4 0.0 2.3 3 0 0 3 3 3 1 Strictosidine synthase NHL PF01436.21 EPS34012.1 - 0.0028 17.6 0.0 2.4 8.3 0.0 2.8 2 0 0 2 2 2 2 NHL repeat PAP_assoc PF03828.19 EPS34012.1 - 0.15 12.3 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 Cid1 family poly A polymerase Pkinase PF00069.25 EPS34013.1 - 8.6e-72 241.7 0.0 1.3e-71 241.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS34013.1 - 2.5e-44 151.5 0.0 3.9e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 EPS34013.1 - 5.3e-22 77.9 0.1 1.9e-21 76.2 0.1 2.0 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 EPS34013.1 - 2.1e-06 27.3 0.0 3.5e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EPS34013.1 - 2.1e-06 26.8 0.0 2.1e-06 26.8 0.0 2.4 3 0 0 3 3 3 1 Fungal protein kinase APH PF01636.23 EPS34013.1 - 0.053 13.4 0.1 0.59 10.0 0.1 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EPS34013.1 - 0.074 12.4 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DSHCT PF08148.12 EPS34013.1 - 0.12 12.0 0.2 0.45 10.2 0.0 1.9 2 0 0 2 2 2 0 DSHCT (NUC185) domain VHS PF00790.19 EPS34014.1 - 3.6e-37 127.3 0.5 6e-37 126.6 0.5 1.4 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.28 EPS34014.1 - 6.2e-17 60.9 0.1 4.2e-16 58.3 0.0 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EPS34014.1 - 1.4e-14 53.7 0.0 2.6e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EPS34014.1 - 2.3e-14 52.8 0.0 4.4e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.14 EPS34014.1 - 6.2e-10 39.3 1.4 6.2e-10 39.3 1.4 2.0 2 0 0 2 2 2 1 GAT domain UIM PF02809.20 EPS34014.1 - 0.028 14.3 2.3 0.071 13.1 2.3 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif adh_short PF00106.25 EPS34015.1 - 7e-14 51.7 0.0 2.9e-13 49.7 0.0 1.8 1 1 1 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS34015.1 - 1.3e-10 41.2 0.0 9e-10 38.5 0.0 2.0 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase EutH PF04346.12 EPS34015.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 Ethanolamine utilisation protein, EutH UCH_1 PF13423.6 EPS34016.1 - 6.5e-96 321.7 0.3 8.8e-96 321.3 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 EPS34016.1 - 8.9e-15 55.6 0.0 3.6e-14 53.7 0.0 2.1 3 0 0 3 3 3 1 Exonuclease UCH PF00443.29 EPS34016.1 - 4.6e-05 23.1 0.0 0.00028 20.5 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CcmH PF03918.14 EPS34016.1 - 0.12 11.6 0.1 0.24 10.7 0.1 1.4 1 0 0 1 1 1 0 Cytochrome C biogenesis protein GTP_EFTU PF00009.27 EPS34017.1 - 3.6e-49 166.9 0.0 6e-49 166.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 EPS34017.1 - 6.5e-20 71.2 1.4 1.3e-19 70.3 1.4 1.5 1 0 0 1 1 1 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.17 EPS34017.1 - 2.8e-09 37.3 0.1 1.8e-08 34.7 0.0 2.5 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EPS34017.1 - 3.8e-08 33.6 0.0 9.8e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EPS34017.1 - 1.1e-07 31.9 0.1 4e-06 26.9 0.1 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EPS34017.1 - 0.00035 20.1 0.1 0.054 12.9 0.1 2.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EPS34017.1 - 0.002 17.5 0.1 0.0044 16.4 0.1 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 EPS34017.1 - 0.0027 17.2 0.0 2.4 7.6 0.0 2.4 1 1 1 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 EPS34017.1 - 0.0043 17.3 0.1 1.9 8.7 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Met_asp_mut_E PF06368.11 EPS34017.1 - 0.017 13.6 0.0 0.03 12.8 0.0 1.2 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) Ras PF00071.22 EPS34017.1 - 0.037 13.6 0.1 0.93 9.1 0.0 2.2 2 0 0 2 2 2 0 Ras family FeoB_N PF02421.18 EPS34017.1 - 0.055 13.0 0.5 1.5 8.3 0.3 2.8 2 1 0 2 2 2 0 Ferrous iron transport protein B RNA_pol_Rpc82 PF05645.13 EPS34017.1 - 0.1 12.3 0.0 0.1 12.3 0.0 2.3 3 0 0 3 3 3 0 RNA polymerase III subunit RPC82 G-alpha PF00503.20 EPS34017.1 - 0.16 11.1 0.3 1.9 7.5 0.1 2.3 3 0 0 3 3 3 0 G-protein alpha subunit HSP70 PF00012.20 EPS34018.1 - 1.6e-261 868.8 12.5 1.8e-261 868.6 12.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EPS34018.1 - 9.3e-18 64.1 0.7 1.9e-16 59.8 0.2 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.10 EPS34018.1 - 0.004 16.2 0.2 0.02 13.9 0.2 1.9 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain BcrAD_BadFG PF01869.20 EPS34018.1 - 0.037 13.5 0.1 3.2 7.2 0.0 2.5 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Drf_FH3 PF06367.16 EPS34018.1 - 0.073 12.7 3.0 0.31 10.6 1.7 2.2 2 0 0 2 2 2 0 Diaphanous FH3 Domain Hydantoinase_A PF01968.18 EPS34018.1 - 0.2 10.9 4.8 0.63 9.3 0.4 3.3 3 1 1 4 4 4 0 Hydantoinase/oxoprolinase FtsA PF14450.6 EPS34018.1 - 1.6 9.2 7.7 8.3 6.9 0.2 3.6 3 2 0 3 3 3 0 Cell division protein FtsA Haem_degrading PF03928.14 EPS34019.1 - 6.5e-30 103.6 0.0 1e-29 103.0 0.0 1.3 1 1 0 1 1 1 1 Haem-degrading Fungal_trans PF04082.18 EPS34021.1 - 3.2e-32 111.6 0.5 1e-31 110.0 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS34021.1 - 2.4e-06 27.6 14.1 7.2e-06 26.0 14.1 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_mis_repair PF01119.19 EPS34021.1 - 0.15 11.8 0.1 0.29 10.8 0.1 1.4 1 0 0 1 1 1 0 DNA mismatch repair protein, C-terminal domain Zn_clus PF00172.18 EPS34022.1 - 4e-05 23.6 13.5 6.1e-05 23.1 13.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Enkurin PF13864.6 EPS34022.1 - 0.22 12.0 0.9 0.38 11.2 0.9 1.4 1 0 0 1 1 1 0 Calmodulin-binding GFA PF04828.14 EPS34023.1 - 0.026 14.9 0.0 0.042 14.2 0.0 1.3 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme MSC PF09402.10 EPS34025.1 - 6.8e-112 374.3 0.0 9.9e-112 373.7 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.7 EPS34025.1 - 4.2e-16 58.4 0.2 8.6e-16 57.4 0.2 1.6 1 0 0 1 1 1 1 HeH/LEM domain RNR_Alpha PF17975.1 EPS34025.1 - 0.14 12.7 0.2 0.31 11.5 0.2 1.5 1 0 0 1 1 1 0 Ribonucleotide reductase alpha domain Thymopoietin PF08198.11 EPS34025.1 - 0.18 11.5 0.1 0.39 10.4 0.1 1.5 1 0 0 1 1 1 0 Thymopoietin protein PP2C PF00481.21 EPS34026.1 - 8.6e-49 166.5 0.0 1.4e-48 165.8 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 EPS34026.1 - 3.3e-33 113.2 58.8 7.2e-07 28.9 0.8 11.4 5 3 11 16 16 16 13 Leucine rich repeat LRR_4 PF12799.7 EPS34026.1 - 3.4e-30 103.6 60.5 0.0014 19.0 0.8 13.3 10 1 2 13 13 13 10 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 EPS34026.1 - 7.2e-25 87.7 0.0 1.7e-24 86.4 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_9 PF14580.6 EPS34026.1 - 1.2e-06 28.1 14.9 0.0013 18.3 0.6 4.8 2 1 3 5 5 5 4 Leucine-rich repeat Ad_cyc_g-alpha PF08509.11 EPS34026.1 - 4.6e-06 26.3 0.0 1.4e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain LRR_1 PF00560.33 EPS34026.1 - 0.00011 22.3 44.8 7.3 7.6 0.5 14.3 13 3 0 13 13 13 1 Leucine Rich Repeat LRR_5 PF13306.6 EPS34026.1 - 0.01 15.8 7.1 5.9 6.9 0.0 4.4 3 2 1 4 4 4 0 BspA type Leucine rich repeat region (6 copies) adh_short PF00106.25 EPS34027.1 - 4.9e-21 75.1 0.0 5.9e-14 52.0 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EPS34027.1 - 2.6e-12 46.8 0.0 4.4e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPS34027.1 - 0.00013 21.9 0.1 0.00021 21.3 0.1 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EPS34027.1 - 0.0087 15.2 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF1422 PF07226.11 EPS34027.1 - 0.088 12.8 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1422) Glyco_hydro_16 PF00722.21 EPS34028.1 - 5.9e-46 156.1 4.2 1.1e-45 155.2 4.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Big_2 PF02368.18 EPS34028.1 - 0.0072 16.2 1.6 0.043 13.7 0.1 2.6 2 0 0 2 2 2 1 Bacterial Ig-like domain (group 2) His_Phos_1 PF00300.22 EPS34029.1 - 1.2e-28 100.1 0.5 3.2e-14 53.1 0.2 3.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) MIP PF00230.20 EPS34030.1 - 4.3e-55 186.9 8.4 5.3e-55 186.6 8.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein FGGY_C PF02782.16 EPS34031.1 - 1.3e-72 243.7 0.4 2.1e-72 243.1 0.4 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EPS34031.1 - 3.6e-66 223.2 0.0 5.1e-66 222.7 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain p450 PF00067.22 EPS34032.1 - 5.9e-63 213.2 0.0 8.1e-63 212.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 IMS PF00817.20 EPS34033.1 - 1.9e-41 141.5 0.0 3.6e-41 140.6 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family REV1_C PF16727.5 EPS34033.1 - 1.8e-25 89.2 0.5 3.6e-25 88.2 0.5 1.6 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain UBM PF14377.6 EPS34033.1 - 3.8e-14 51.6 12.9 1.8e-08 33.5 4.2 3.5 3 0 0 3 3 3 2 Ubiquitin binding region IMS_C PF11799.8 EPS34033.1 - 4.4e-14 53.2 0.0 1.6e-13 51.4 0.0 1.9 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 EPS34033.1 - 5.9e-09 36.2 0.0 1.2e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain IMS_HHH PF11798.8 EPS34033.1 - 9.6e-06 25.6 0.0 3.7e-05 23.8 0.0 2.1 1 0 0 1 1 1 1 IMS family HHH motif BRCT PF00533.26 EPS34033.1 - 4.6e-05 23.7 0.0 0.00011 22.6 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EPS34033.1 - 0.00058 19.7 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain mCpol PF18182.1 EPS34033.1 - 0.021 15.2 0.0 0.043 14.1 0.0 1.5 1 0 0 1 1 1 0 minimal CRISPR polymerase domain CSTF_C PF14304.6 EPS34033.1 - 0.031 13.8 0.3 1.3 8.7 0.0 2.5 2 0 0 2 2 2 0 Transcription termination and cleavage factor C-terminal FKBP_C PF00254.28 EPS34034.1 - 3.5e-32 110.6 0.0 1.1e-31 109.0 0.0 1.9 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 EPS34034.1 - 1.1e-23 83.8 3.0 1.1e-23 83.8 3.0 2.7 2 2 0 2 2 2 1 Nucleoplasmin-like domain Pkinase PF00069.25 EPS34035.1 - 1.6e-47 162.1 0.1 7.9e-26 91.0 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 EPS34035.1 - 2e-20 73.2 0.1 9e-11 41.5 0.0 3.1 2 1 1 3 3 3 2 Protein tyrosine kinase APH PF01636.23 EPS34035.1 - 0.0015 18.5 2.7 0.0019 18.2 0.4 2.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EPS34035.1 - 0.1 11.5 0.1 0.23 10.4 0.1 1.5 1 0 0 1 1 1 0 Haspin like kinase domain Pox_ser-thr_kin PF05445.11 EPS34035.1 - 0.13 11.2 0.0 0.21 10.5 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF3591 PF12157.8 EPS34036.1 - 1.2e-179 597.7 0.2 1.5e-179 597.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC PF00098.23 EPS34036.1 - 0.0054 16.8 0.7 0.009 16.1 0.7 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.6 EPS34036.1 - 0.0068 16.2 1.2 0.017 15.0 1.2 1.7 1 0 0 1 1 1 1 Zinc knuckle GRASP55_65 PF04495.14 EPS34037.1 - 5.6e-43 146.6 0.0 1.2e-40 139.0 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_6 PF17820.1 EPS34037.1 - 0.00037 20.3 0.0 0.11 12.3 0.0 2.9 2 0 0 2 2 2 2 PDZ domain ApoO PF09769.9 EPS34038.1 - 7.3e-42 142.4 0.3 5.9e-41 139.5 0.1 2.3 3 0 0 3 3 3 1 Apolipoprotein O Peptidase_M3 PF01432.20 EPS34039.1 - 1.9e-119 400.0 0.0 3e-119 399.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 DASH_Dad3 PF08656.10 EPS34039.1 - 0.12 12.4 0.0 0.47 10.6 0.0 2.0 1 0 0 1 1 1 0 DASH complex subunit Dad3 BTG PF07742.12 EPS34039.1 - 0.16 11.8 0.0 2.4 8.0 0.0 2.8 3 0 0 3 3 3 0 BTG family Pox_A_type_inc PF04508.12 EPS34042.1 - 0.061 13.2 11.1 27 4.8 0.5 7.3 6 0 0 6 6 6 0 Viral A-type inclusion protein repeat Filament PF00038.21 EPS34042.1 - 0.88 9.1 169.4 0.062 12.9 4.4 8.2 1 1 4 6 6 6 0 Intermediate filament protein PTPA PF03095.15 EPS34045.1 - 1.9e-116 388.8 0.0 2.2e-116 388.6 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF572 PF04502.13 EPS34046.1 - 7.3e-75 252.6 0.3 8.1e-75 252.5 0.3 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) PAS_9 PF13426.7 EPS34048.1 - 3.2e-12 46.6 0.0 8.3e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EPS34048.1 - 0.017 15.1 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 PAS fold PAS_4 PF08448.10 EPS34048.1 - 0.028 14.7 0.0 0.11 12.8 0.0 2.0 2 0 0 2 2 2 0 PAS fold Sugar_tr PF00083.24 EPS34049.1 - 4.2e-83 279.7 20.6 5e-83 279.4 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS34049.1 - 6.1e-27 94.5 53.5 5e-25 88.2 26.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EPS34049.1 - 0.0022 16.4 6.3 1.8 6.8 0.0 3.2 2 1 1 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family DUF3959 PF13105.6 EPS34049.1 - 0.098 12.1 5.9 0.019 14.5 2.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3959) GTP_EFTU PF00009.27 EPS34050.1 - 2.2e-29 102.4 0.0 3e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EPS34050.1 - 2.3e-13 50.4 0.0 1.2e-12 48.1 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EPS34050.1 - 1.6e-06 28.4 0.0 5.1e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EPS34050.1 - 4.7e-06 26.7 0.1 6.8e-05 22.9 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EPS34050.1 - 0.022 14.8 0.8 0.87 9.6 0.2 2.3 1 1 1 2 2 2 0 Dynamin family FeoB_N PF02421.18 EPS34050.1 - 0.14 11.6 0.0 2.8 7.4 0.0 2.8 3 0 0 3 3 3 0 Ferrous iron transport protein B APH PF01636.23 EPS34051.1 - 4.2e-08 33.4 0.0 7.5e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.20 EPS34051.1 - 0.0025 17.2 0.0 0.0036 16.7 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Glyco_hydro_12 PF01670.16 EPS34052.1 - 1.7e-20 73.9 5.0 5.8e-20 72.2 5.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 Period_C PF12114.8 EPS34052.1 - 8.6 5.9 5.9 13 5.3 5.9 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Glyco_tranf_2_3 PF13641.6 EPS34054.1 - 4e-21 76.0 0.0 1.1e-20 74.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EPS34054.1 - 1.9e-17 63.8 0.9 1.9e-17 63.8 0.9 2.2 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Cellulose_synt PF03552.14 EPS34054.1 - 2.1e-14 53.0 7.8 1.2e-09 37.3 2.0 4.0 2 1 2 4 4 4 2 Cellulose synthase Glycos_transf_2 PF00535.26 EPS34054.1 - 1.9e-12 47.3 0.0 3.1e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EPS34054.1 - 4e-12 45.9 0.0 6.2e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.15 EPS34054.1 - 0.038 12.6 0.1 0.1 11.2 0.0 1.8 2 1 0 2 2 2 0 Chitin synthase FAD_binding_7 PF03441.14 EPS34055.1 - 5.6e-74 248.0 0.7 8.6e-74 247.4 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 EPS34055.1 - 5.5e-40 137.1 0.0 1.8e-39 135.4 0.1 1.8 2 0 0 2 2 2 1 DNA photolyase MFS_1 PF07690.16 EPS34056.1 - 2.6e-44 151.6 53.0 5.3e-44 150.6 50.0 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS34056.1 - 7.2e-17 61.4 31.9 3.2e-15 56.0 18.7 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.13 EPS34056.1 - 8.7e-15 54.2 16.0 8.7e-15 54.2 16.0 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_3_C PF01915.22 EPS34057.1 - 4e-48 164.1 0.1 1.5e-47 162.2 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 EPS34057.1 - 3.8e-46 157.9 0.0 5.7e-46 157.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Fn3-like PF14310.6 EPS34057.1 - 3e-21 75.3 0.0 6.1e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain AhpC-TSA PF00578.21 EPS34058.1 - 1.5e-29 102.5 0.0 2e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EPS34058.1 - 2.1e-13 50.2 0.0 2.7e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EPS34058.1 - 2.1e-13 49.9 0.3 3.5e-13 49.2 0.3 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA_2 PF13911.6 EPS34058.1 - 0.11 12.7 0.0 0.26 11.4 0.0 1.5 1 1 0 1 1 1 0 AhpC/TSA antioxidant enzyme Gly_transf_sug PF04488.15 EPS34059.1 - 2e-13 50.8 0.0 4.2e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 EPS34059.1 - 0.0023 17.4 0.1 0.0034 16.8 0.1 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Methyltransf_15 PF09445.10 EPS34060.1 - 1.2e-48 164.8 0.0 1.5e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.16 EPS34060.1 - 2e-09 37.5 0.0 2.7e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.15 EPS34060.1 - 2.9e-06 27.0 0.0 3.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.18 EPS34060.1 - 8.6e-06 25.6 0.0 1.5e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 EPS34060.1 - 0.00034 20.4 0.0 0.00041 20.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPS34060.1 - 0.0011 19.7 0.0 0.0021 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EPS34060.1 - 0.0041 17.1 0.0 0.0062 16.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS34060.1 - 0.0089 16.7 0.0 0.018 15.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_5 PF01795.19 EPS34060.1 - 0.02 14.4 0.0 0.028 13.9 0.0 1.1 1 0 0 1 1 1 0 MraW methylase family DNA_methylase PF00145.17 EPS34060.1 - 0.029 13.7 0.0 0.042 13.2 0.0 1.2 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase Methyltransf_3 PF01596.17 EPS34060.1 - 0.23 10.6 0.0 0.38 9.9 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase DUF1679 PF07914.11 EPS34060.1 - 0.24 10.2 0.1 0.31 9.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) bZIP_1 PF00170.21 EPS34061.1 - 0.0011 19.0 8.5 0.002 18.2 8.5 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EPS34061.1 - 0.0081 16.2 7.8 0.012 15.6 7.8 1.3 1 0 0 1 1 1 1 Basic region leucine zipper CK_II_beta PF01214.18 EPS34063.1 - 2.7e-77 258.7 0.0 9e-77 257.0 0.0 1.7 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.8 EPS34063.1 - 0.42 11.6 21.7 0.051 14.5 6.7 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Fungal_trans PF04082.18 EPS34064.1 - 4.8e-17 61.9 0.7 6.8e-17 61.4 0.1 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS34064.1 - 1.6e-07 31.4 13.6 2.6e-07 30.6 13.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_3 PF13738.6 EPS34065.1 - 1.5e-08 34.3 0.1 0.00036 19.9 0.1 3.2 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.19 EPS34065.1 - 7.7e-08 31.2 0.4 6.5e-07 28.1 0.4 2.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.6 EPS34065.1 - 9.6e-07 28.9 0.0 2.3e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EPS34065.1 - 1.2e-06 27.9 0.4 0.00031 20.0 0.2 3.2 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EPS34065.1 - 0.021 14.1 0.0 0.054 12.7 0.0 1.6 1 0 0 1 1 1 0 Thi4 family LIN52 PF10044.9 EPS34065.1 - 0.024 15.3 0.0 0.069 13.9 0.0 1.7 1 0 0 1 1 1 0 Retinal tissue protein Cupin_8 PF13621.6 EPS34066.1 - 1.6e-27 96.8 0.0 2.7e-27 96.1 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EPS34066.1 - 0.0001 21.9 0.0 0.00033 20.2 0.0 1.8 3 0 0 3 3 3 1 Cupin superfamily protein Cupin_2 PF07883.11 EPS34066.1 - 0.052 13.3 0.0 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 Cupin domain Pkinase PF00069.25 EPS34067.1 - 6e-20 71.7 0.0 8.5e-19 67.9 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS34067.1 - 1.9e-07 30.6 0.0 3.7e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase AA_permease PF00324.21 EPS34069.1 - 2.4e-102 343.0 42.9 8.2e-102 341.2 42.9 1.7 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EPS34069.1 - 4e-14 52.3 36.7 8.9e-14 51.1 36.7 1.5 1 1 0 1 1 1 1 Amino acid permease DUF1772 PF08592.11 EPS34069.1 - 0.024 14.9 3.2 0.024 14.9 3.2 3.8 2 1 2 4 4 4 0 Domain of unknown function (DUF1772) zf-C2H2_2 PF12756.7 EPS34070.1 - 1.3e-35 121.7 21.2 1.6e-31 108.6 4.1 3.2 2 1 1 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 EPS34070.1 - 2.8e-06 27.5 7.6 2.8e-06 27.5 7.6 3.6 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EPS34070.1 - 3.1e-05 24.2 5.9 3.1e-05 24.2 5.9 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type DUF2024 PF09630.10 EPS34070.1 - 0.053 13.4 4.3 4.1 7.4 0.7 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2024) zf-LYAR PF08790.11 EPS34070.1 - 0.14 12.1 7.4 0.2 11.6 1.7 3.0 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2 PF00096.26 EPS34070.1 - 0.65 10.6 19.1 0.75 10.4 1.2 3.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type Cytochrome_C554 PF13435.6 EPS34070.1 - 1 10.3 10.0 20 6.2 0.2 3.7 3 0 0 3 3 3 0 Cytochrome c554 and c-prime DUF3847 PF12958.7 EPS34070.1 - 3.6 7.8 7.0 0.57 10.3 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) zf-C2H2_4 PF13894.6 EPS34070.1 - 6.9 7.8 17.8 0.65 11.0 1.6 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger HECT PF00632.25 EPS34071.1 - 7.1e-70 235.9 0.0 4.1e-69 233.4 0.0 2.0 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 EPS34071.1 - 2.5e-21 75.6 0.8 1.3e-20 73.4 0.8 2.4 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A FANCI_S2 PF14676.6 EPS34071.1 - 0.13 12.6 0.1 0.6 10.4 0.0 2.1 2 0 0 2 2 2 0 FANCI solenoid 2 His_Phos_1 PF00300.22 EPS34072.1 - 1.8e-13 50.7 0.4 3.6e-13 49.6 0.4 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) 2-Hacid_dh_C PF02826.19 EPS34074.1 - 2.3e-53 180.2 0.0 3.6e-53 179.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EPS34074.1 - 2.6e-31 108.0 0.2 3.8e-31 107.5 0.2 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AlaDh_PNT_C PF01262.21 EPS34074.1 - 0.024 13.9 1.8 0.74 9.1 1.6 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.6 EPS34074.1 - 0.073 13.6 0.0 0.21 12.1 0.0 1.8 1 0 0 1 1 1 0 XdhC Rossmann domain Fungal_trans_2 PF11951.8 EPS34075.1 - 1.2e-09 37.5 0.1 1.7e-09 37.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS34075.1 - 4.6e-07 29.8 6.8 7.9e-07 29.1 6.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fe-ADH PF00465.19 EPS34076.1 - 9e-106 353.7 0.0 1.2e-105 353.4 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EPS34076.1 - 7.1e-15 55.4 0.0 7.1e-11 42.3 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.6 EPS34076.1 - 0.0043 16.8 0.0 0.0076 16.0 0.0 1.4 1 0 0 1 1 1 1 Periplasmic binding protein COPIIcoated_ERV PF07970.12 EPS34077.1 - 0.059 13.2 0.0 0.061 13.2 0.0 1.1 1 0 0 1 1 1 0 Endoplasmic reticulum vesicle transporter Bys1 PF04681.12 EPS34078.1 - 6.9e-10 39.1 0.1 9.6e-10 38.6 0.1 1.3 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Rad10 PF03834.14 EPS34079.1 - 2.7e-47 159.5 0.0 4e-47 158.9 0.0 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.6 EPS34079.1 - 3e-05 24.5 0.0 5.7e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.23 EPS34079.1 - 0.00089 19.0 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_2 PF12826.7 EPS34079.1 - 0.048 13.8 0.0 0.088 12.9 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif RRM_1 PF00076.22 EPS34080.1 - 1.9e-58 194.2 0.0 4e-17 61.8 0.1 5.6 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 EPS34080.1 - 0.0042 17.1 0.0 2.4 8.2 0.0 2.7 2 0 0 2 2 2 2 DbpA RNA binding domain Limkain-b1 PF11608.8 EPS34080.1 - 0.0065 16.5 0.2 0.27 11.3 0.0 3.6 3 2 0 3 3 3 1 Limkain b1 RRM_occluded PF16842.5 EPS34080.1 - 0.013 15.3 0.0 16 5.4 0.0 3.4 3 0 0 3 3 3 0 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 EPS34080.1 - 0.025 14.4 0.1 7.4 6.3 0.0 3.2 2 1 1 3 3 3 0 Rrp7 RRM-like N-terminal domain RRM_5 PF13893.6 EPS34080.1 - 0.027 14.1 0.0 2.7 7.6 0.0 2.4 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EPS34080.1 - 0.15 12.2 0.0 20 5.4 0.0 3.6 3 1 0 3 3 3 0 RNA recognition motif TFIIA PF03153.13 EPS34080.1 - 4.2 7.3 32.8 0.041 13.9 9.8 2.5 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Cyt-b5 PF00173.28 EPS34081.1 - 1.8e-08 34.4 0.0 2.1e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain APH PF01636.23 EPS34082.1 - 1.5e-08 34.9 0.0 2.9e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF21 PF01595.20 EPS34083.1 - 1.1e-31 109.9 0.1 1.8e-31 109.2 0.1 1.3 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 EPS34083.1 - 0.00015 22.1 0.1 0.037 14.5 0.0 3.0 2 0 0 2 2 2 2 CBS domain DUF4023 PF13215.6 EPS34083.1 - 0.25 11.4 5.9 0.63 10.1 5.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4023) Occludin_ELL PF07303.13 EPS34084.1 - 0.0082 16.9 0.0 0.0082 16.9 0.0 5.1 4 2 2 6 6 6 1 Occludin homology domain DcrB PF08786.11 EPS34084.1 - 0.13 12.3 8.3 1.7 8.8 0.1 3.5 2 1 0 2 2 2 0 DcrB MukB PF04310.12 EPS34084.1 - 0.18 11.6 0.9 0.55 10.0 0.2 2.2 2 1 0 2 2 2 0 MukB N-terminal Hydantoinase_B PF02538.14 EPS34084.1 - 1.6 7.0 4.0 1.5 7.1 2.3 1.8 2 0 0 2 2 2 0 Hydantoinase B/oxoprolinase OrsD PF12013.8 EPS34084.1 - 5.8 7.4 5.3 58 4.2 0.3 3.4 2 1 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D Transket_pyr PF02779.24 EPS34085.1 - 5.2e-44 150.0 0.0 7.7e-44 149.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EPS34085.1 - 2.1e-32 111.6 0.0 5.5e-32 110.3 0.0 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain Arginosuc_synth PF00764.19 EPS34086.1 - 7.7e-156 519.2 0.0 8.9e-156 519.0 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 EPS34086.1 - 0.012 15.1 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 EPS34086.1 - 0.031 13.1 0.0 0.046 12.5 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase SplA PF11132.8 EPS34087.1 - 0.082 12.7 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Transcriptional regulator protein (SplA) PT PF04886.12 EPS34088.1 - 1.3e-07 31.0 19.6 6.6e-05 22.4 6.7 2.5 1 1 1 2 2 2 2 PT repeat Peptidase_M20 PF01546.28 EPS34089.1 - 1.8e-21 76.8 0.0 3.2e-20 72.7 0.0 2.4 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 WD40 PF00400.32 EPS34089.1 - 9.3e-07 29.5 9.9 0.051 14.5 0.1 6.3 6 0 0 6 6 6 2 WD domain, G-beta repeat M20_dimer PF07687.14 EPS34089.1 - 6.6e-06 26.0 0.0 1.3e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF5471 PF17565.2 EPS34089.1 - 0.49 10.7 2.3 1.2 9.5 2.3 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5471) Pkinase PF00069.25 EPS34090.1 - 9.3e-16 58.0 0.0 1.8e-15 57.0 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS34090.1 - 3.5e-08 33.0 0.0 3.5e-07 29.8 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Aminotran_4 PF01063.19 EPS34091.1 - 8.4e-37 127.2 0.0 1.2e-36 126.7 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV Peptidase_M49 PF03571.15 EPS34092.1 - 2.4e-245 815.1 0.0 3.1e-245 814.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 2C_adapt PF08793.10 EPS34092.1 - 0.16 12.2 0.1 0.39 10.9 0.1 1.7 1 0 0 1 1 1 0 2-cysteine adaptor domain SNF5 PF04855.12 EPS34094.1 - 2e-86 289.6 0.0 2.6e-86 289.3 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.27 EPS34094.1 - 0.00015 21.3 2.1 0.00015 21.3 2.1 2.2 1 1 1 2 2 2 1 GATA zinc finger Rubredoxin_2 PF18073.1 EPS34094.1 - 0.12 12.2 5.5 0.54 10.0 1.4 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain HEPN_DZIP3 PF18738.1 EPS34096.1 - 0.12 12.1 0.5 3.1 7.6 0.2 2.3 1 1 1 2 2 2 0 DZIP3/ hRUL138-like HEPN WD40 PF00400.32 EPS34097.1 - 1.3e-24 86.0 21.8 1.4e-05 25.7 0.5 7.0 6 2 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS34097.1 - 7.5e-10 39.0 8.7 0.00077 19.7 0.3 4.8 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 EPS34097.1 - 2.6e-05 24.2 8.2 0.019 14.9 0.3 2.5 1 1 0 2 2 2 2 Transcription factor IIIC subunit delta N-term F-box-like PF12937.7 EPS34098.1 - 6e-07 29.3 0.0 1.5e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 F-box-like Sugar_tr PF00083.24 EPS34099.1 - 7.7e-106 354.7 13.1 9.4e-106 354.4 13.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS34099.1 - 4.4e-29 101.5 24.4 4.4e-29 101.5 24.4 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EPS34099.1 - 7.7e-07 27.9 5.4 1.6e-06 26.9 5.4 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) LacY_symp PF01306.19 EPS34099.1 - 0.00076 18.4 7.7 0.044 12.6 2.0 2.4 2 0 0 2 2 2 2 LacY proton/sugar symporter MFS_3 PF05977.13 EPS34099.1 - 0.0044 15.5 1.4 0.0044 15.5 1.4 2.6 2 1 0 2 2 2 2 Transmembrane secretion effector Phage_holin_3_2 PF04550.12 EPS34099.1 - 0.27 11.8 6.0 1.2 9.7 6.0 2.1 1 0 0 1 1 1 0 Phage holin family 2 MFS_1_like PF12832.7 EPS34099.1 - 0.27 10.0 16.1 0.0086 15.0 4.0 2.7 1 1 2 3 3 3 0 MFS_1 like family ABC_tran PF00005.27 EPS34100.1 - 3e-48 163.8 2.8 4.8e-23 82.2 0.0 3.2 3 1 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EPS34100.1 - 3.3e-20 71.9 7.8 3.3e-20 71.9 7.8 4.3 5 0 0 5 5 4 1 ABC transporter AAA_21 PF13304.6 EPS34100.1 - 2.3e-15 57.2 2.9 0.0032 17.3 0.2 4.8 4 1 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EPS34100.1 - 9e-12 44.9 0.5 0.0038 16.7 0.0 4.5 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EPS34100.1 - 1.3e-08 35.6 12.2 0.0036 17.8 0.0 5.1 5 0 0 5 5 5 2 AAA domain AAA_22 PF13401.6 EPS34100.1 - 1.6e-07 31.7 0.0 0.0012 19.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EPS34100.1 - 1.9e-06 27.5 0.1 0.1 12.3 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EPS34100.1 - 2.4e-06 27.6 0.6 0.038 13.9 0.1 2.8 2 1 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EPS34100.1 - 2.6e-06 27.9 0.3 0.097 13.0 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 EPS34100.1 - 2.6e-06 27.5 0.4 0.056 13.5 0.1 3.0 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 EPS34100.1 - 4.8e-06 27.2 2.9 0.14 12.7 0.0 3.6 4 0 0 4 4 3 2 AAA domain AAA_30 PF13604.6 EPS34100.1 - 7.9e-06 25.7 0.1 0.0026 17.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 EPS34100.1 - 2.7e-05 24.5 1.6 0.24 11.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 EPS34100.1 - 5.7e-05 23.3 0.2 0.76 9.9 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_24 PF13479.6 EPS34100.1 - 0.00013 21.8 0.0 0.62 9.7 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 EPS34100.1 - 0.00059 20.3 0.0 0.53 10.7 0.1 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.23 EPS34100.1 - 0.0009 19.3 2.8 0.61 10.1 0.0 3.8 4 0 0 4 4 4 1 Dynamin family NACHT PF05729.12 EPS34100.1 - 0.001 19.0 0.0 0.84 9.5 0.0 2.8 2 0 0 2 2 2 1 NACHT domain Rad17 PF03215.15 EPS34100.1 - 0.0012 18.8 0.4 0.16 11.9 0.0 3.2 2 1 0 3 3 3 1 Rad17 P-loop domain AAA_14 PF13173.6 EPS34100.1 - 0.0016 18.5 0.0 3.5 7.7 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_27 PF13514.6 EPS34100.1 - 0.0017 18.0 0.1 2.9 7.4 0.0 3.5 4 0 0 4 4 2 1 AAA domain RNA_helicase PF00910.22 EPS34100.1 - 0.0019 18.5 0.0 1.3 9.4 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Zeta_toxin PF06414.12 EPS34100.1 - 0.0027 17.0 1.4 1.7 7.9 0.1 3.4 3 0 0 3 3 3 1 Zeta toxin MeaB PF03308.16 EPS34100.1 - 0.0028 16.7 1.6 2 7.3 0.0 3.0 3 0 0 3 3 3 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 EPS34100.1 - 0.0078 15.7 0.0 1.3 8.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region Roc PF08477.13 EPS34100.1 - 0.0082 16.4 0.0 7.4 6.8 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ATP-synt_ab PF00006.25 EPS34100.1 - 0.0089 15.7 0.0 0.57 9.8 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_15 PF13175.6 EPS34100.1 - 0.0098 15.6 18.2 0.18 11.5 0.0 4.8 3 1 1 4 4 4 2 AAA ATPase domain NB-ARC PF00931.22 EPS34100.1 - 0.01 15.1 0.2 3.8 6.6 0.0 2.6 2 1 0 2 2 2 0 NB-ARC domain cobW PF02492.19 EPS34100.1 - 0.016 14.8 1.8 1.2 8.7 0.3 2.7 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.14 EPS34100.1 - 0.016 15.1 0.1 0.39 10.6 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.22 EPS34100.1 - 0.017 14.8 0.0 0.91 9.1 0.1 2.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 EPS34100.1 - 0.024 14.5 0.2 2.2 8.2 0.2 2.8 2 0 0 2 2 2 0 NTPase AAA_5 PF07728.14 EPS34100.1 - 0.028 14.4 0.2 10 6.1 0.0 3.0 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) FeoB_N PF02421.18 EPS34100.1 - 0.066 12.7 0.1 3.4 7.2 0.0 2.9 3 0 0 3 3 3 0 Ferrous iron transport protein B TsaE PF02367.17 EPS34100.1 - 0.069 13.2 0.1 7.8 6.5 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 EPS34100.1 - 0.075 12.8 0.0 13 5.5 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arf PF00025.21 EPS34100.1 - 0.1 12.0 0.1 1.2 8.6 0.1 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family PRK PF00485.18 EPS34100.1 - 0.38 10.5 0.0 0.38 10.5 0.0 2.7 4 0 0 4 4 3 0 Phosphoribulokinase / Uridine kinase family U1snRNP70_N PF12220.8 EPS34100.1 - 0.62 10.7 3.3 9.6 6.9 0.8 2.9 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal AAA_17 PF13207.6 EPS34100.1 - 0.88 10.0 7.1 19 5.7 0.2 3.8 4 0 0 4 4 3 0 AAA domain DUF87 PF01935.17 EPS34100.1 - 1.1 9.3 0.0 1.1 9.3 0.0 4.6 6 1 0 6 6 5 0 Helicase HerA, central domain Seryl_tRNA_N PF02403.22 EPS34100.1 - 2.4 8.4 14.6 0.047 13.9 1.3 3.3 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain MadM PF03818.13 EPS34103.1 - 0.097 12.6 0.8 0.097 12.6 0.8 1.6 2 0 0 2 2 2 0 Malonate/sodium symporter MadM subunit DUF2070 PF09843.9 EPS34103.1 - 0.55 8.5 9.9 0.56 8.4 9.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) MFS_1 PF07690.16 EPS34104.1 - 7.4e-40 137.0 35.7 7.4e-40 137.0 35.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS34104.1 - 7.7e-11 41.5 8.2 7.7e-11 41.5 8.2 2.0 2 1 0 2 2 2 1 Sugar (and other) transporter Glyco_transf_54 PF04666.13 EPS34106.1 - 3.1e-13 49.2 0.0 1.4e-09 37.3 0.0 3.1 2 1 0 2 2 2 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Tetraspanin PF00335.20 EPS34106.1 - 0.18 11.5 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Tetraspanin family SKG6 PF08693.10 EPS34108.1 - 1.6e-10 40.2 4.8 1.6e-10 40.2 4.8 2.7 4 0 0 4 4 2 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 EPS34108.1 - 0.0055 16.5 0.1 0.008 16.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Stevor PF17410.2 EPS34108.1 - 0.021 14.4 0.1 0.033 13.8 0.1 1.2 1 0 0 1 1 1 0 Subtelomeric Variable Open Reading frame CcmD PF04995.14 EPS34108.1 - 0.033 14.3 0.8 0.058 13.5 0.8 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) RIFIN PF02009.16 EPS34108.1 - 0.037 13.9 0.0 0.06 13.2 0.0 1.3 1 1 0 1 1 1 0 Rifin DcuC PF03606.15 EPS34108.1 - 0.06 11.8 0.1 0.081 11.4 0.1 1.1 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier DUF3301 PF11743.8 EPS34108.1 - 0.22 11.2 0.1 0.37 10.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3301) Phage_holin_2_4 PF16082.5 EPS34108.1 - 0.27 11.0 2.5 0.92 9.3 2.5 2.0 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Peptidase_M56 PF05569.11 EPS34108.1 - 0.4 9.8 0.0 0.4 9.8 0.0 1.8 2 0 0 2 2 2 0 BlaR1 peptidase M56 Apt1 PF10351.9 EPS34108.1 - 1.6 7.5 7.4 2.3 7.0 7.4 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain TFIIA PF03153.13 EPS34108.1 - 2.6 7.9 7.3 3.9 7.4 7.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ank_2 PF12796.7 EPS34109.1 - 1.9e-30 105.3 3.3 2.2e-11 44.1 0.0 4.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPS34109.1 - 2.4e-26 91.7 2.7 4.8e-08 33.4 0.0 6.0 4 1 3 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EPS34109.1 - 3e-16 59.3 2.8 0.00073 19.8 0.1 5.3 2 2 4 6 6 6 5 Ankyrin repeats (many copies) SPX PF03105.19 EPS34109.1 - 1.8e-15 57.8 7.1 3.2e-08 33.9 0.5 2.2 1 1 1 2 2 2 2 SPX domain Ank_3 PF13606.6 EPS34109.1 - 2.9e-15 54.8 4.8 0.0026 18.1 0.0 7.0 8 0 0 8 8 8 3 Ankyrin repeat GDPD PF03009.17 EPS34109.1 - 5.4e-13 49.3 0.0 3.4e-12 46.6 0.0 2.0 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank PF00023.30 EPS34109.1 - 2.5e-09 37.1 7.7 0.003 17.9 0.0 6.7 6 1 0 6 6 6 2 Ankyrin repeat NUP PF06516.11 EPS34109.1 - 0.16 11.2 0.1 0.31 10.2 0.1 1.5 2 0 0 2 2 2 0 Purine nucleoside permease (NUP) DUF1279 PF06916.13 EPS34110.1 - 1e-26 93.3 0.0 1.6e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Wtap PF17098.5 EPS34110.1 - 0.16 11.9 2.7 0.24 11.3 2.7 1.2 1 0 0 1 1 1 0 WTAP/Mum2p family Ribosomal_L3 PF00297.22 EPS34111.1 - 4.3e-18 65.4 5.8 2.9e-16 59.4 1.8 2.2 1 1 1 2 2 2 2 Ribosomal protein L3 Coa1 PF08695.10 EPS34112.1 - 1.6e-43 147.1 0.1 2e-43 146.8 0.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF2298 PF10060.9 EPS34113.1 - 0.0013 17.6 0.4 0.0015 17.3 0.4 1.0 1 0 0 1 1 1 1 Uncharacterized membrane protein (DUF2298) SUR7 PF06687.12 EPS34113.1 - 0.016 14.8 0.1 0.031 13.9 0.0 1.4 2 0 0 2 2 2 0 SUR7/PalI family FA_desaturase PF00487.24 EPS34113.1 - 0.018 14.9 1.9 0.019 14.8 0.6 1.6 1 1 0 1 1 1 0 Fatty acid desaturase GET2 PF08690.10 EPS34113.1 - 0.073 12.7 0.0 0.099 12.3 0.0 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 DUF3040 PF11239.8 EPS34113.1 - 3.7 7.9 6.9 0.4 11.0 1.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) zf-4CXXC_R1 PF10497.9 EPS34114.1 - 1.7e-09 37.8 12.3 1.7e-09 37.8 12.3 2.5 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 JmjC PF02373.22 EPS34114.1 - 3.7e-09 37.0 0.2 1.7e-07 31.7 0.2 2.8 2 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 EPS34114.1 - 0.018 14.8 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 Cupin domain UbiA PF01040.18 EPS34115.1 - 3e-42 144.6 18.6 4.1e-42 144.2 18.6 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Glutaredoxin PF00462.24 EPS34116.1 - 1.4e-15 57.2 0.0 2.4e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin CTP_transf_like PF01467.26 EPS34117.1 - 1.5e-23 83.6 0.0 1.1e-20 74.2 0.0 2.8 3 0 0 3 3 3 2 Cytidylyltransferase-like PRELI PF04707.14 EPS34119.1 - 1.7e-43 148.2 0.1 2e-43 148.0 0.1 1.0 1 0 0 1 1 1 1 PRELI-like family BRCA-2_OB3 PF09104.10 EPS34119.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 3 AhpC-TSA PF00578.21 EPS34120.1 - 2.3e-22 79.2 0.0 3.2e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EPS34120.1 - 6.7e-15 55.1 0.1 9e-15 54.7 0.1 1.2 1 0 0 1 1 1 1 Redoxin Cytomega_UL84 PF06284.11 EPS34120.1 - 4.8 5.5 4.9 6.1 5.2 4.9 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Nop14 PF04147.12 EPS34120.1 - 6.9 4.8 17.1 11 4.1 17.1 1.3 1 0 0 1 1 1 0 Nop14-like family RskA PF10099.9 EPS34121.1 - 0.051 13.9 2.5 0.067 13.5 2.5 1.2 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF1761 PF08570.10 EPS34122.1 - 1.6e-25 89.8 3.2 1.8e-25 89.6 3.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) Methyltransf_16 PF10294.9 EPS34123.1 - 4.5e-48 163.3 0.0 5.6e-48 162.9 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EPS34123.1 - 0.0085 15.9 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EPS34123.1 - 0.09 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Mpp10 PF04006.12 EPS34124.1 - 4.8e-112 375.4 38.5 1.8e-111 373.6 38.5 1.8 1 1 0 1 1 1 1 Mpp10 protein adh_short_C2 PF13561.6 EPS34125.1 - 2.4e-58 197.5 0.0 2.9e-58 197.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPS34125.1 - 3e-46 157.4 0.0 3.8e-46 157.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPS34125.1 - 4.6e-14 52.7 0.0 6.3e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 KR domain IL12 PF03039.14 EPS34125.1 - 0.18 11.1 0.0 13 5.0 0.0 2.2 2 0 0 2 2 2 0 Interleukin-12 alpha subunit Oxidored_q6 PF01058.22 EPS34126.1 - 3.1e-22 78.8 0.1 5.4e-22 78.0 0.1 1.4 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Sedlin_N PF04628.13 EPS34127.1 - 1.8e-14 54.0 0.0 2.4e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Acyl_transf_1 PF00698.21 EPS34128.1 - 8.5e-25 87.9 0.0 5.8e-18 65.5 0.0 2.1 2 0 0 2 2 2 2 Acyl transferase domain Nucleoporin_C PF03177.14 EPS34129.1 - 1.3e-158 529.4 0.1 1.6e-158 529.1 0.1 1.0 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.11 EPS34129.1 - 2.3e-68 230.9 0.0 3e-68 230.6 0.0 1.1 1 0 0 1 1 1 1 Nup133 N terminal like HABP4_PAI-RBP1 PF04774.15 EPS34130.1 - 0.34 11.8 2.9 0.42 11.5 2.9 1.4 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family Nab1 PF04902.12 EPS34132.1 - 0.14 12.5 0.9 0.76 10.2 0.1 1.9 1 1 1 2 2 2 0 Conserved region in Nab1 APH PF01636.23 EPS34135.1 - 7.3e-05 22.8 0.0 0.00011 22.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family OrfB_Zn_ribbon PF07282.11 EPS34136.1 - 0.058 13.3 0.6 0.11 12.5 0.6 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain APH PF01636.23 EPS34137.1 - 6.1e-10 39.4 1.2 1e-08 35.4 1.2 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EPS34137.1 - 0.00022 20.9 0.9 0.00069 19.3 0.4 1.9 1 1 1 2 2 2 1 Choline/ethanolamine kinase HMG_box_2 PF09011.10 EPS34137.1 - 0.2 12.3 0.0 0.35 11.5 0.0 1.4 1 0 0 1 1 1 0 HMG-box domain TetR_C_18 PF17923.1 EPS34138.1 - 0.08 13.5 0.0 1.5 9.3 0.0 2.2 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Helo_like_N PF17111.5 EPS34141.1 - 1.7e-31 109.3 11.0 4.9e-28 97.9 2.7 2.0 2 0 0 2 2 2 2 Fungal N-terminal domain of STAND proteins PRESAN PF09687.10 EPS34141.1 - 0.024 15.2 0.4 0.073 13.6 0.0 1.9 1 1 1 2 2 2 0 Plasmodium RESA N-terminal Syntaxin-6_N PF09177.11 EPS34141.1 - 0.029 14.9 3.2 0.34 11.5 0.6 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal 4HB_MCP_1 PF12729.7 EPS34141.1 - 0.031 13.8 4.4 0.93 9.0 0.4 2.1 1 1 1 2 2 2 0 Four helix bundle sensory module for signal transduction TetR_C_27 PF17935.1 EPS34141.1 - 0.051 13.6 0.6 0.14 12.2 0.1 1.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF5320 PF17253.2 EPS34141.1 - 0.096 13.8 0.1 25 6.0 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5320) DUF883 PF05957.13 EPS34141.1 - 0.29 11.8 2.0 1.7 9.3 0.2 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Inhibitor_I9 PF05922.16 EPS34142.1 - 0.09 13.5 0.4 0.14 12.8 0.3 1.4 1 1 0 1 1 1 0 Peptidase inhibitor I9 Dicty_REP PF05086.12 EPS34142.1 - 2.7 5.8 7.4 2.9 5.8 7.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Tetrabrachion PF11401.8 EPS34143.1 - 0.065 13.2 1.1 0.17 11.9 1.1 1.8 1 1 0 1 1 1 0 Tetrabrachion Ribonuclease_3 PF00636.26 EPS34144.1 - 6.7e-14 52.4 0.0 2.1e-13 50.8 0.0 1.9 1 1 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 EPS34144.1 - 1.2e-13 51.3 0.0 2.8e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease-III-like MRP-S33 PF08293.11 EPS34145.1 - 1.3e-30 105.4 0.0 1.6e-30 105.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 EF_assoc_1 PF08355.12 EPS34145.1 - 0.062 12.9 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 EF hand associated ER_lumen_recept PF00810.18 EPS34146.1 - 9.8e-55 185.4 8.0 9.8e-55 185.4 8.0 1.5 2 0 0 2 2 2 1 ER lumen protein retaining receptor PQ-loop PF04193.14 EPS34146.1 - 0.022 14.5 16.2 0.43 10.4 0.3 3.9 3 1 1 4 4 4 0 PQ loop repeat Integrase_H2C2 PF17921.1 EPS34147.1 - 1.3e-07 31.6 0.8 1.3e-07 31.6 0.8 2.7 3 0 0 3 3 3 1 Integrase zinc binding domain XRCC4 PF06632.12 EPS34151.1 - 1.5e-05 24.1 16.9 1.5e-05 24.1 16.9 2.0 1 1 1 2 2 2 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 Baseplate PF16774.5 EPS34151.1 - 0.018 14.9 0.7 0.029 14.3 0.7 1.2 1 0 0 1 1 1 0 Baseplate protein Molybdopterin PF00384.22 EPS34152.1 - 4.5e-69 233.5 0.0 1.2e-34 120.1 0.0 2.2 1 1 1 2 2 2 2 Molybdopterin oxidoreductase Fer2_4 PF13510.6 EPS34152.1 - 1.6e-20 72.9 0.2 4.5e-20 71.5 0.2 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH_dhqG_C PF09326.11 EPS34152.1 - 7.4e-20 71.4 0.1 2.3e-19 69.8 0.1 2.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal NADH-G_4Fe-4S_3 PF10588.9 EPS34152.1 - 2.7e-17 62.0 0.2 2.7e-17 62.0 0.2 2.2 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 EPS34152.1 - 2.1e-08 34.0 0.5 2.1e-08 34.0 0.5 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.27 EPS34152.1 - 0.11 12.3 1.1 3.4 7.6 0.3 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_19 PF06902.11 EPS34152.1 - 0.86 9.7 3.5 9.1 6.4 2.2 2.8 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster Fer4_4 PF12800.7 EPS34152.1 - 8.7 7.1 6.5 1.5 9.5 1.6 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain TPT PF03151.16 EPS34153.1 - 3.2e-62 210.5 13.2 4e-62 210.2 13.2 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EPS34153.1 - 3.5e-09 37.0 30.7 7.5e-06 26.2 10.5 2.8 2 1 0 2 2 2 2 EamA-like transporter family PSII PF00421.19 EPS34153.1 - 0.0031 16.3 0.0 0.0051 15.5 0.0 1.3 1 0 0 1 1 1 1 Photosystem II protein UAA PF08449.11 EPS34153.1 - 0.012 14.8 13.2 0.032 13.4 4.5 2.2 2 0 0 2 2 2 0 UAA transporter family PUF PF00806.19 EPS34154.1 - 3e-34 114.8 4.2 9.8e-07 28.1 0.0 8.2 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat ATG16 PF08614.11 EPS34154.1 - 0.0038 17.5 2.8 0.0061 16.8 2.8 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) CPL PF08144.11 EPS34154.1 - 0.027 14.8 0.4 9.6 6.6 0.0 3.4 3 1 1 4 4 4 0 CPL (NUC119) domain DUF5572 PF17733.1 EPS34155.1 - 2.3e-23 81.8 1.0 4.2e-23 80.9 0.4 1.8 2 0 0 2 2 2 1 Family of unknown function (DUF5572) Ssl1 PF04056.14 EPS34156.1 - 2.2e-75 252.7 0.0 3e-75 252.3 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 EPS34156.1 - 5.6e-19 68.1 7.4 5.6e-19 68.1 7.4 2.3 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 EPS34156.1 - 1.7e-16 60.8 0.0 3.6e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 EPS34156.1 - 7.7e-07 29.5 0.0 1.1e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.14 EPS34156.1 - 0.0072 15.9 0.6 0.012 15.1 0.6 1.4 1 0 0 1 1 1 1 Transcription factor Tfb4 DZR PF12773.7 EPS34156.1 - 0.38 10.8 21.7 0.43 10.6 5.3 3.2 2 1 0 2 2 2 0 Double zinc ribbon zinc_ribbon_15 PF17032.5 EPS34156.1 - 5.3 7.9 13.7 13 6.6 2.1 2.6 2 1 0 2 2 2 0 zinc-ribbon family ERAP1_C PF11838.8 EPS34157.1 - 1.5e-84 284.3 2.3 1.5e-84 284.3 2.3 1.6 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1 PF01433.20 EPS34157.1 - 1.4e-78 263.5 3.8 2.2e-78 262.8 3.8 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EPS34157.1 - 4.9e-45 154.0 0.1 3.6e-43 147.9 0.1 2.6 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Ras PF00071.22 EPS34158.1 - 9.7e-66 220.3 0.5 1.1e-65 220.1 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EPS34158.1 - 6.7e-36 123.1 0.1 1.2e-35 122.3 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPS34158.1 - 2.5e-16 59.6 0.1 2.9e-16 59.4 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EPS34158.1 - 2.3e-05 24.4 0.0 8.7e-05 22.6 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EPS34158.1 - 2.7e-05 24.1 0.3 0.13 12.2 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EPS34158.1 - 0.00012 21.7 0.4 0.00031 20.3 0.2 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EPS34158.1 - 0.00025 20.5 0.1 0.00032 20.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA PF00004.29 EPS34158.1 - 0.00053 20.4 0.1 0.2 12.1 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.10 EPS34158.1 - 0.00086 18.8 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EPS34158.1 - 0.0057 16.2 0.0 0.035 13.6 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 EPS34158.1 - 0.0089 16.4 0.0 0.013 15.9 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EPS34158.1 - 0.029 14.6 0.0 0.067 13.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain Septin PF00735.18 EPS34158.1 - 0.036 13.3 0.1 0.18 11.1 0.0 1.9 2 0 0 2 2 2 0 Septin AAA_29 PF13555.6 EPS34158.1 - 0.057 13.2 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain TniB PF05621.11 EPS34158.1 - 0.067 12.6 0.0 0.21 11.0 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein AAA_5 PF07728.14 EPS34158.1 - 0.067 13.2 0.0 0.12 12.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 EPS34158.1 - 0.068 13.7 0.1 0.15 12.5 0.1 1.8 1 1 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 EPS34158.1 - 0.077 12.6 0.1 2.2 7.8 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_7 PF12775.7 EPS34158.1 - 0.09 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 EPS34158.1 - 0.094 12.5 0.1 1.2 8.9 0.0 2.3 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Mito_carr PF00153.27 EPS34159.1 - 5.8e-54 180.0 2.9 3.3e-17 62.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein AphA_like PF14557.6 EPS34159.1 - 0.0029 17.3 0.0 0.0047 16.7 0.0 1.3 1 0 0 1 1 1 1 Putative AphA-like transcriptional regulator HMD PF03201.16 EPS34159.1 - 0.06 13.6 0.0 8.3 6.7 0.0 3.2 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase UcrQ PF02939.16 EPS34159.1 - 0.073 13.0 0.1 0.25 11.3 0.0 1.9 2 0 0 2 2 2 0 UcrQ family WD40 PF00400.32 EPS34160.1 - 3.6e-07 30.8 6.3 0.25 12.3 0.0 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat WW PF00397.26 EPS34161.1 - 4.8e-12 45.7 4.0 8.9e-12 44.9 4.0 1.5 1 0 0 1 1 1 1 WW domain DUF2076 PF09849.9 EPS34161.1 - 0.0048 17.0 32.3 0.0048 17.0 32.3 3.0 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF2012 PF09430.10 EPS34162.1 - 1.9e-29 102.3 0.0 2.6e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) HLH PF00010.26 EPS34165.1 - 3.5e-13 49.3 0.6 6.9e-13 48.3 0.6 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3439 PF11921.8 EPS34165.1 - 3 7.8 16.2 3.6 7.6 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) RNA_pol_Rpc82 PF05645.13 EPS34166.1 - 2e-29 103.2 0.0 1.3e-24 87.4 0.0 2.7 2 2 0 2 2 2 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 EPS34166.1 - 3.1e-16 59.2 1.0 1.3e-08 34.7 0.0 3.8 4 0 0 4 4 4 3 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 EPS34166.1 - 0.00092 19.0 0.1 0.01 15.6 0.0 2.5 2 0 0 2 2 2 1 TFIIE alpha subunit AbiEi_4 PF13338.6 EPS34166.1 - 0.048 13.8 0.4 49 4.2 0.0 3.5 3 0 0 3 3 3 0 Transcriptional regulator, AbiEi antitoxin Peptidase_M16 PF00675.20 EPS34167.1 - 2.4e-19 69.8 0.0 4.3e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EPS34167.1 - 1.7e-12 47.7 0.0 3.8e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16 inactive domain DUF2303 PF10065.9 EPS34169.1 - 0.26 10.4 0.0 0.29 10.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2303) Mito_carr PF00153.27 EPS34170.1 - 3.3e-28 97.4 4.4 2.7e-13 49.6 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Citrate_synt PF00285.21 EPS34171.1 - 2.5e-99 332.8 0.0 3.1e-99 332.4 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain CTD_bind PF04818.13 EPS34172.1 - 4.6e-09 37.0 0.0 8e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_1 PF00076.22 EPS34172.1 - 0.00012 21.8 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AA_permease_2 PF13520.6 EPS34174.1 - 1.1e-56 192.5 56.2 1.3e-56 192.2 56.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPS34174.1 - 1.8e-19 69.7 46.9 2.4e-19 69.3 46.9 1.1 1 0 0 1 1 1 1 Amino acid permease Pho88 PF10032.9 EPS34174.1 - 0.53 9.5 2.6 13 5.0 0.2 2.3 2 0 0 2 2 2 0 Phosphate transport (Pho88) Hexokinase_1 PF00349.21 EPS34175.1 - 1.9e-59 200.9 0.0 3.1e-59 200.2 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.16 EPS34175.1 - 3.4e-59 200.2 0.0 7.1e-58 195.9 0.0 2.1 1 1 0 1 1 1 1 Hexokinase Cys_Met_Meta_PP PF01053.20 EPS34177.1 - 1.6e-147 491.0 0.0 1.9e-147 490.8 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EPS34177.1 - 5.2e-11 42.5 0.4 9.7e-11 41.6 0.4 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.21 EPS34177.1 - 1.2e-09 37.9 0.1 2.3e-09 36.9 0.1 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EPS34177.1 - 1.2e-05 24.5 0.5 1.7e-05 23.9 0.1 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EPS34177.1 - 0.00023 20.5 0.0 0.00038 19.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 EPS34177.1 - 0.0005 18.7 0.0 0.00068 18.3 0.0 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase Asparaginase_C PF17763.1 EPS34177.1 - 0.035 14.3 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain SepSecS PF05889.13 EPS34177.1 - 0.1 11.3 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS ABC_sub_bind PF04392.12 EPS34177.1 - 0.14 11.4 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 ABC transporter substrate binding protein MARVEL PF01284.23 EPS34178.1 - 1.5e-21 76.9 18.9 1.8e-21 76.7 18.9 1.0 1 0 0 1 1 1 1 Membrane-associating domain AA_permease PF00324.21 EPS34179.1 - 1e-134 449.7 46.8 1.2e-134 449.5 46.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EPS34179.1 - 4.7e-32 111.4 51.7 5.9e-32 111.0 51.7 1.1 1 0 0 1 1 1 1 Amino acid permease AMP-binding PF00501.28 EPS34180.1 - 1.4e-88 297.3 0.0 1.8e-88 297.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Septin PF00735.18 EPS34182.1 - 4.4e-14 52.4 0.0 1.2e-09 37.8 0.0 2.2 2 0 0 2 2 2 2 Septin AAA PF00004.29 EPS34182.1 - 0.0076 16.7 0.0 0.014 15.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EPS34182.1 - 0.014 15.7 0.0 0.034 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EPS34182.1 - 0.029 13.8 0.0 0.059 12.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 EPS34182.1 - 0.032 14.8 0.0 0.068 13.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 EPS34182.1 - 0.038 14.4 1.3 0.072 13.5 0.1 2.1 2 1 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 EPS34182.1 - 0.046 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin DUF815 PF05673.13 EPS34182.1 - 0.05 12.8 0.0 0.081 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 EPS34182.1 - 0.085 12.9 0.0 0.23 11.5 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EPS34182.1 - 0.1 12.5 0.0 0.48 10.3 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_33 PF13671.6 EPS34182.1 - 0.1 12.8 0.1 0.31 11.2 0.0 2.0 2 0 0 2 2 1 0 AAA domain Viral_helicase1 PF01443.18 EPS34182.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 EPS34182.1 - 0.19 11.2 0.0 0.35 10.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TIP49 PF06068.13 EPS34182.1 - 0.25 10.5 0.0 0.37 9.9 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_29 PF13555.6 EPS34182.1 - 0.26 11.1 1.1 0.48 10.2 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain UL42 PF17638.2 EPS34182.1 - 2.4 8.1 5.8 16 5.5 1.1 2.7 2 0 0 2 2 2 0 HCMV UL42 ABM PF03992.16 EPS34184.1 - 5.6e-05 23.2 0.1 7.5e-05 22.8 0.1 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase FemAB_like PF04339.12 EPS34184.1 - 0.033 13.3 0.1 0.037 13.2 0.1 1.0 1 0 0 1 1 1 0 Peptidogalycan biosysnthesis/recognition SelP_N PF04592.14 EPS34184.1 - 0.045 13.2 0.3 0.05 13.0 0.3 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region HSP90 PF00183.18 EPS34185.1 - 3.9e-222 738.7 31.7 5.1e-222 738.4 31.7 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 EPS34185.1 - 3.1e-15 56.7 0.1 5.6e-15 55.8 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EPS34185.1 - 5.5e-10 39.2 0.1 5.5e-10 39.2 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1676 PF07898.13 EPS34185.1 - 2.6 8.0 6.9 0.81 9.7 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) NTF2 PF02136.20 EPS34186.1 - 1.9e-25 89.7 0.2 3.2e-25 89.0 0.2 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 EPS34186.1 - 3.4e-06 26.8 0.1 6.3e-06 25.9 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EPS34186.1 - 0.09 12.8 2.5 0.12 12.5 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif TPR_11 PF13414.6 EPS34188.1 - 0.025 14.3 5.2 0.99 9.1 0.1 4.2 4 0 0 4 4 4 0 TPR repeat TPR_17 PF13431.6 EPS34188.1 - 0.77 10.3 4.6 26 5.5 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Nnf1 PF03980.14 EPS34189.1 - 7.2e-35 119.7 5.5 7.2e-35 119.7 5.5 1.9 1 1 1 2 2 2 1 Nnf1 FlgN PF05130.12 EPS34189.1 - 0.00079 20.0 8.9 0.0064 17.0 7.6 2.2 1 1 2 3 3 3 1 FlgN protein Apolipoprotein PF01442.18 EPS34189.1 - 0.017 15.0 5.3 0.017 15.0 5.3 2.3 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF948 PF06103.11 EPS34189.1 - 0.03 14.6 1.2 0.1 12.9 0.4 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) ApoLp-III PF07464.11 EPS34189.1 - 0.033 14.3 3.0 1.7 8.7 1.1 2.3 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Csm1_N PF18504.1 EPS34189.1 - 0.085 13.2 0.7 0.085 13.2 0.7 2.3 2 0 0 2 2 2 0 Csm1 N-terminal domain SHE3 PF17078.5 EPS34189.1 - 0.11 12.2 0.2 0.11 12.2 0.2 1.9 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 DUF16 PF01519.16 EPS34189.1 - 0.14 12.7 2.2 0.93 10.0 2.2 2.0 1 1 0 1 1 1 0 Protein of unknown function DUF16 APG6_N PF17675.1 EPS34189.1 - 0.67 10.5 9.0 1.4 9.5 2.6 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF4404 PF14357.6 EPS34189.1 - 1 10.0 11.5 0.89 10.2 4.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) TMPIT PF07851.13 EPS34189.1 - 2.2 7.5 5.2 0.33 10.1 1.3 1.5 2 0 0 2 2 2 0 TMPIT-like protein Syntaxin-6_N PF09177.11 EPS34189.1 - 3.5 8.2 6.5 11 6.6 4.0 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal COG2 PF06148.11 EPS34189.1 - 4.2 7.5 8.2 1.4 9.1 1.7 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Endonuc_Holl PF10107.9 EPS34189.1 - 6.3 6.6 7.6 1 9.2 1.2 2.2 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase 7tm_2 PF00002.24 EPS34190.1 - 3.7e-10 39.5 5.6 6.3e-10 38.8 5.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 EPS34190.1 - 4.1e-09 36.0 16.5 1.3e-08 34.3 8.4 2.1 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor Git3 PF11710.8 EPS34190.1 - 0.0003 20.6 9.0 0.0003 20.6 9.0 1.9 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 DUF5438 PF17506.2 EPS34190.1 - 0.12 12.8 0.5 0.42 10.9 0.3 2.1 1 1 0 1 1 1 0 Family of unknown function (DUF5438) TMEMspv1-c74-12 PF11044.8 EPS34190.1 - 0.13 12.2 0.2 0.27 11.2 0.2 1.5 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Pkinase PF00069.25 EPS34191.1 - 1.1e-75 254.5 0.0 1.3e-75 254.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS34191.1 - 2.4e-36 125.4 0.0 3.5e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EPS34191.1 - 9.7e-05 21.5 0.0 0.0011 18.0 0.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EPS34191.1 - 0.029 13.7 0.2 0.029 13.7 0.2 1.8 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EPS34191.1 - 0.037 13.3 2.8 0.061 12.6 0.0 2.5 2 1 0 3 3 3 0 Kinase-like APH PF01636.23 EPS34191.1 - 0.047 13.6 2.2 0.054 13.4 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EPS34191.1 - 0.093 11.8 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Spt20 PF12090.8 EPS34191.1 - 0.45 10.1 6.8 0.82 9.2 6.8 1.4 1 0 0 1 1 1 0 Spt20 family SIR2 PF02146.17 EPS34192.1 - 5.6e-32 111.1 0.0 7.6e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 Sir2 family Cation_efflux PF01545.21 EPS34193.1 - 2.2e-59 200.5 7.0 2.7e-59 200.2 7.0 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EPS34193.1 - 2.1e-05 24.5 0.0 5e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter FGGY_C PF02782.16 EPS34194.1 - 2.3e-34 118.8 0.0 6e-34 117.5 0.0 1.7 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 EPS34194.1 - 7.5e-21 74.8 0.0 1.8e-14 53.9 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Xpo1 PF08389.12 EPS34195.1 - 6.9e-41 139.8 0.2 5.8e-40 136.8 0.0 2.8 2 0 0 2 2 2 1 Exportin 1-like protein HEAT PF02985.22 EPS34195.1 - 0.00036 20.5 2.7 15 6.2 0.0 6.1 7 0 0 7 7 7 1 HEAT repeat 14-3-3 PF00244.20 EPS34195.1 - 0.13 11.8 0.1 0.28 10.6 0.1 1.6 1 0 0 1 1 1 0 14-3-3 protein Esterase PF00756.20 EPS34196.1 - 4.8e-54 183.6 0.1 6e-54 183.3 0.1 1.0 1 0 0 1 1 1 1 Putative esterase Esterase_phd PF10503.9 EPS34196.1 - 1.6e-06 27.8 0.0 9.8e-05 21.9 0.0 2.1 2 0 0 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.21 EPS34196.1 - 1.5e-05 24.6 0.1 2.3e-05 24.0 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EPS34196.1 - 0.00038 19.8 0.0 0.0023 17.2 0.0 2.1 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 EPS34196.1 - 0.007 15.3 0.0 0.014 14.3 0.0 1.5 1 1 0 1 1 1 1 Chlorophyllase enzyme Lipase_3 PF01764.25 EPS34196.1 - 0.012 15.5 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) AXE1 PF05448.12 EPS34196.1 - 0.054 12.1 0.0 0.075 11.7 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 EPS34196.1 - 0.056 13.3 0.0 0.17 11.7 0.0 1.8 1 1 1 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 EPS34196.1 - 0.067 12.8 0.2 0.23 11.1 0.2 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 EPS34196.1 - 0.068 12.9 0.0 0.094 12.4 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Chlorophyllase PF07224.11 EPS34196.1 - 0.11 11.4 0.0 0.4 9.6 0.0 1.7 2 0 0 2 2 2 0 Chlorophyllase Abhydrolase_2 PF02230.16 EPS34196.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_C50 PF03568.17 EPS34197.1 - 2.4e-158 527.4 0.0 3.2e-157 523.7 0.0 2.4 2 0 0 2 2 2 1 Peptidase family C50 TPR_2 PF07719.17 EPS34197.1 - 9.9e-07 28.4 6.2 1.2 9.4 0.1 6.2 5 0 0 5 5 5 2 Tetratricopeptide repeat CHAT PF12770.7 EPS34197.1 - 1.1e-05 25.0 0.7 0.00062 19.3 0.0 2.9 3 0 0 3 3 3 1 CHAT domain TPR_1 PF00515.28 EPS34197.1 - 1.5e-05 24.6 1.9 5.5 7.0 0.1 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EPS34197.1 - 3.5e-05 24.0 28.0 0.41 11.0 0.0 7.1 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EPS34197.1 - 7.1e-05 22.3 11.1 0.083 12.3 1.6 3.8 3 1 0 3 3 3 2 MalT-like TPR region TPR_14 PF13428.6 EPS34197.1 - 0.031 15.1 17.1 0.41 11.6 0.0 6.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 EPS34197.1 - 0.25 12.0 13.2 11 6.8 0.1 6.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 EPS34197.1 - 0.28 11.5 1.3 98 3.6 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 EPS34197.1 - 4.7 7.2 5.9 19 5.3 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF5321 PF17254.2 EPS34198.1 - 2.5e-60 202.5 3.5 3.3e-60 202.1 3.5 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5321) Qua1 PF16274.5 EPS34198.1 - 0.075 12.9 0.2 0.22 11.4 0.2 1.8 1 0 0 1 1 1 0 Qua1 domain HXXSHH PF07586.11 EPS34198.1 - 0.11 12.0 1.4 0.17 11.4 1.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1552) Mito_carr PF00153.27 EPS34199.1 - 7.1e-73 240.6 0.1 1.8e-25 88.7 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 EPS34199.1 - 3.1e-15 56.4 1.3 5.2e-09 36.4 0.6 3.4 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EPS34199.1 - 1.4e-14 52.7 0.2 2.5e-07 30.1 0.0 5.4 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.32 EPS34199.1 - 2.4e-14 51.7 2.3 1.6e-07 30.4 0.0 5.3 7 0 0 7 7 7 3 EF hand EF-hand_8 PF13833.6 EPS34199.1 - 4.2e-09 36.1 0.1 0.14 12.0 0.0 4.9 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 EPS34199.1 - 2.8e-08 32.9 2.2 5.2e-07 28.9 0.0 3.3 4 0 0 4 4 4 1 EF hand Serine_protease PF18405.1 EPS34199.1 - 0.3 10.2 0.7 11 5.0 0.0 3.2 2 1 2 4 4 4 0 Gammaproteobacterial serine protease PAP2_3 PF14378.6 EPS34200.1 - 3.5e-37 127.9 14.9 5.5e-37 127.3 14.9 1.3 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.6 EPS34200.1 - 0.0078 16.7 2.0 0.0078 16.7 2.0 2.6 2 0 0 2 2 2 1 PAP2 superfamily C-terminal PAP2 PF01569.21 EPS34200.1 - 0.25 11.1 13.9 0.47 10.2 11.4 2.3 1 1 1 2 2 2 0 PAP2 superfamily Arc_C PF18162.1 EPS34201.1 - 0.16 11.9 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 Arc C-lobe PAP2 PF01569.21 EPS34203.1 - 3.8 7.3 9.5 1.3 8.8 1.9 2.9 3 0 0 3 3 3 0 PAP2 superfamily Peptidase_M22 PF00814.25 EPS34204.1 - 1.2e-42 146.5 0.0 7.1e-42 144.0 0.0 2.1 1 1 0 1 1 1 1 Glycoprotease family YycC PF14174.6 EPS34204.1 - 0.073 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 YycC-like protein EPL1 PF10513.9 EPS34206.1 - 7e-33 114.2 0.0 1.6e-32 113.1 0.0 1.7 1 0 0 1 1 1 1 Enhancer of polycomb-like zf-HC5HC2H_2 PF13832.6 EPS34206.1 - 2.5e-30 104.9 5.1 2.5e-30 104.9 5.1 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EPS34206.1 - 6.3e-26 90.5 1.4 6.3e-26 90.5 1.4 3.0 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 EPS34206.1 - 5.3e-15 54.7 8.4 7.9e-14 50.9 2.3 2.6 2 0 0 2 2 2 2 PHD-finger PHD PF00628.29 EPS34206.1 - 3.3e-10 39.7 20.5 7.6e-09 35.3 9.5 2.7 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.6 EPS34206.1 - 1.3 8.6 10.5 0.016 14.8 1.7 2.1 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.6 EPS34206.1 - 4.9 7.2 15.1 0.83 9.6 7.2 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.11 EPS34206.1 - 7.2 7.0 20.6 0.061 13.6 5.4 2.6 2 0 0 2 2 2 0 RING-like domain RRM_1 PF00076.22 EPS34207.1 - 2.7e-20 71.9 0.0 3.9e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EPS34207.1 - 0.0004 20.0 0.0 0.00056 19.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dpy-30 PF05186.13 EPS34208.1 - 9.2e-14 50.9 0.1 1.2e-13 50.5 0.1 1.2 1 0 0 1 1 1 1 Dpy-30 motif VRR_NUC PF08774.11 EPS34209.1 - 6.2e-24 84.1 0.0 1.8e-23 82.6 0.0 1.9 1 0 0 1 1 1 1 VRR-NUC domain Ribosomal_S13_N PF08069.12 EPS34210.1 - 5.9e-29 99.9 0.0 9.4e-29 99.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 EPS34210.1 - 1e-14 54.5 0.1 1.4e-14 54.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.18 EPS34210.1 - 0.012 15.5 0.2 0.029 14.3 0.0 1.6 2 0 0 2 2 2 0 'Paired box' domain OGG_N PF07934.12 EPS34211.1 - 6.4e-35 119.9 0.1 1.2e-34 119.0 0.1 1.5 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 EPS34211.1 - 6.4e-17 62.0 0.0 1.2e-16 61.0 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EPS34211.1 - 0.0055 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif EccE PF11203.8 EPS34211.1 - 0.11 12.9 0.5 20 5.6 0.1 2.7 2 0 0 2 2 2 0 Putative type VII ESX secretion system translocon, EccE RRM_1 PF00076.22 EPS34212.1 - 3.4e-27 94.1 0.1 5.9e-12 45.2 0.0 3.9 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EPS34212.1 - 0.0075 16.1 0.0 0.59 10.0 0.0 3.1 3 0 0 3 3 3 1 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 EPS34212.1 - 0.21 11.4 0.1 0.38 10.5 0.1 1.3 1 0 0 1 1 1 0 Rrp7 RRM-like N-terminal domain GMC_oxred_N PF00732.19 EPS34213.1 - 1.2e-28 100.3 0.0 2e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EPS34213.1 - 4.7e-18 66.1 0.5 9e-18 65.2 0.5 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.24 EPS34213.1 - 5.2e-08 32.9 0.2 0.0081 15.8 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EPS34213.1 - 2.1e-07 30.4 0.5 0.002 17.3 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 EPS34213.1 - 2.8e-06 26.3 0.3 2.6e-05 23.1 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 EPS34213.1 - 1.8e-05 24.1 0.2 0.0034 16.7 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EPS34213.1 - 3.8e-05 23.2 0.2 0.00022 20.7 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EPS34213.1 - 8.6e-05 22.7 0.0 0.00033 20.8 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EPS34213.1 - 0.0014 18.0 0.1 0.0024 17.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 EPS34213.1 - 0.0015 17.8 0.1 0.022 14.0 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPS34213.1 - 0.011 16.3 2.2 0.04 14.5 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EPS34213.1 - 0.044 13.0 0.1 0.096 11.9 0.1 1.5 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 EPS34213.1 - 0.047 12.7 0.0 0.093 11.8 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 EPS34213.1 - 0.051 12.7 0.3 0.11 11.6 0.0 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 EPS34213.1 - 0.11 11.3 0.1 0.17 10.7 0.1 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Tannase PF07519.11 EPS34214.1 - 1.2e-122 410.2 3.9 1.4e-122 410.0 3.9 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Hydrolase_4 PF12146.8 EPS34214.1 - 0.019 14.3 0.0 0.26 10.5 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Zn_clus PF00172.18 EPS34215.1 - 5.6e-07 29.6 11.6 1.2e-06 28.6 11.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.8 EPS34215.1 - 1.9e-06 26.9 0.1 4.7e-05 22.4 0.1 2.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF3048 PF11258.8 EPS34216.1 - 0.099 12.7 0.4 0.12 12.5 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3048) N-terminal domain 7tm_2 PF00002.24 EPS34217.1 - 7.4e-07 28.7 14.9 6.8e-06 25.5 14.6 1.9 1 1 1 2 2 2 2 7 transmembrane receptor (Secretin family) SNARE PF05739.19 EPS34217.1 - 0.29 11.2 2.1 1 9.4 2.1 2.0 1 0 0 1 1 1 0 SNARE domain H_PPase PF03030.16 EPS34217.1 - 0.83 8.2 6.1 0.2 10.3 1.7 1.9 2 1 0 2 2 2 0 Inorganic H+ pyrophosphatase Retinal PF15449.6 EPS34217.1 - 4.6 4.9 7.5 6.2 4.5 7.5 1.0 1 0 0 1 1 1 0 Retinal protein DUF2457 PF10446.9 EPS34217.1 - 9.1 5.3 5.1 13 4.8 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Abhydrolase_6 PF12697.7 EPS34218.1 - 6.5e-19 69.4 4.0 8.4e-19 69.1 4.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_8 PF06259.12 EPS34218.1 - 0.04 13.5 0.1 0.063 12.9 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF900 PF05990.12 EPS34218.1 - 0.13 11.8 0.2 0.2 11.2 0.2 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) UPF0121 PF03661.13 EPS34219.1 - 2.4e-32 112.3 6.6 3.1e-32 111.9 6.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Rax2 PF12768.7 EPS34220.1 - 2.4e-73 246.1 1.3 6.9e-72 241.4 0.0 3.6 3 1 2 5 5 5 1 Cortical protein marker for cell polarity Kelch_6 PF13964.6 EPS34220.1 - 3.2e-05 24.0 0.2 0.27 11.6 0.1 3.7 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.6 EPS34220.1 - 0.086 12.9 0.1 2.9 8.0 0.0 3.3 2 0 0 2 2 2 0 Galactose oxidase, central domain PRIMA1 PF16101.5 EPS34220.1 - 0.21 11.6 0.0 0.78 9.8 0.0 1.9 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Kelch_2 PF07646.15 EPS34220.1 - 8.4 6.5 6.6 20 5.3 0.0 4.3 5 0 0 5 5 5 0 Kelch motif POB3_N PF17292.2 EPS34222.1 - 6.6e-32 109.8 0.2 1.1e-30 105.9 0.0 2.7 3 0 0 3 3 3 1 POB3-like N-terminal PH domain SSrecog PF03531.14 EPS34222.1 - 2.4e-31 107.5 0.0 4.9e-30 103.2 0.0 2.7 3 0 0 3 3 3 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.12 EPS34222.1 - 8.5e-27 93.4 0.0 7e-26 90.5 0.0 2.4 3 0 0 3 3 3 1 Histone chaperone Rttp106-like PH_TFIIH PF08567.11 EPS34222.1 - 0.013 15.8 0.0 0.71 10.2 0.0 3.2 4 0 0 4 4 4 0 TFIIH p62 subunit, N-terminal domain Septin PF00735.18 EPS34223.1 - 9.4e-121 402.4 0.1 9.4e-121 402.4 0.1 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EPS34223.1 - 9e-08 32.2 0.0 2.6e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EPS34223.1 - 1.6e-05 24.6 2.7 0.00086 18.9 0.0 3.1 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 EPS34223.1 - 0.00028 21.4 2.5 0.04 14.4 0.0 2.8 3 0 0 3 3 3 1 ABC transporter AIG1 PF04548.16 EPS34223.1 - 0.001 18.4 0.0 0.001 18.4 0.0 2.1 2 0 0 2 2 2 1 AIG1 family RsgA_GTPase PF03193.16 EPS34223.1 - 0.0012 18.7 0.6 0.0012 18.7 0.6 3.1 3 1 0 3 3 2 1 RsgA GTPase Roc PF08477.13 EPS34223.1 - 0.0014 18.8 0.0 0.0031 17.7 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 EPS34223.1 - 0.0026 18.2 0.1 0.0076 16.6 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EPS34223.1 - 0.0059 16.9 0.7 0.025 14.9 0.0 2.4 2 2 0 2 2 2 1 AAA domain Ras PF00071.22 EPS34223.1 - 0.0066 16.1 0.0 0.021 14.4 0.0 1.9 1 0 0 1 1 1 1 Ras family AAA_29 PF13555.6 EPS34223.1 - 0.018 14.8 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 EPS34223.1 - 0.062 13.0 0.2 0.14 11.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EPS34223.1 - 0.075 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family RNA_helicase PF00910.22 EPS34223.1 - 0.17 12.3 0.5 1 9.8 0.0 2.3 2 0 0 2 2 2 0 RNA helicase Exonuc_VII_L PF02601.15 EPS34223.1 - 0.23 11.0 6.5 0.38 10.3 6.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Dynamin_N PF00350.23 EPS34223.1 - 0.35 10.9 8.9 0.6 10.1 0.0 3.5 2 2 0 3 3 3 0 Dynamin family DUF87 PF01935.17 EPS34223.1 - 0.59 10.2 3.0 5.2 7.1 0.0 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain ATP_bind_1 PF03029.17 EPS34223.1 - 0.66 9.7 5.6 3.5 7.3 0.1 3.2 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein Atg14 PF10186.9 EPS34223.1 - 1.3 8.1 7.3 1.9 7.5 7.3 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3987 PF13148.6 EPS34223.1 - 7.6 5.4 9.0 2.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Aminotran_1_2 PF00155.21 EPS34224.1 - 2.8e-22 79.4 0.0 3.4e-22 79.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EPS34224.1 - 0.017 13.9 0.0 0.51 9.1 0.0 2.2 2 0 0 2 2 2 0 Alanine-glyoxylate amino-transferase Aminotran_1_2 PF00155.21 EPS34225.1 - 7.1e-44 150.4 0.0 9.2e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EPS34225.1 - 1.2e-08 34.4 0.0 7.6e-08 31.7 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EPS34225.1 - 9.9e-07 27.6 0.0 1.4e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 EPS34225.1 - 1.1e-05 24.9 0.0 1.6e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EPS34225.1 - 0.00021 20.7 0.0 0.00031 20.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Fungal_trans_2 PF11951.8 EPS34226.1 - 2.3e-55 188.0 3.4 2.5e-55 187.8 3.4 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain HEAT_2 PF13646.6 EPS34226.1 - 0.12 12.7 0.1 33 5.0 0.0 2.8 2 0 0 2 2 2 0 HEAT repeats DUF3328 PF11807.8 EPS34228.1 - 8.8e-28 97.6 4.1 1.1e-27 97.2 4.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) EamA PF00892.20 EPS34229.1 - 1.2e-12 48.2 20.6 1.9e-06 28.1 8.2 2.4 2 1 0 2 2 2 2 EamA-like transporter family FAD_binding_3 PF01494.19 EPS34230.1 - 6.6e-12 45.3 0.0 0.0026 17.1 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain Pyr_redox_2 PF07992.14 EPS34230.1 - 0.00026 20.3 0.0 0.018 14.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPS34230.1 - 0.012 15.8 0.0 0.026 14.7 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 EPS34230.1 - 0.12 13.0 0.0 0.34 11.5 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Sdh_cyt PF01127.22 EPS34231.1 - 5.6e-17 61.9 3.5 7.9e-17 61.4 3.5 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF2456 PF10445.9 EPS34231.1 - 0.032 14.3 0.3 0.053 13.6 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2456) Methyltransf_2 PF00891.18 EPS34232.1 - 1.1e-23 83.7 0.0 1.7e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation PF08100.11 EPS34232.1 - 0.0016 18.4 1.5 0.018 15.1 0.3 2.5 2 0 0 2 2 2 1 Dimerisation domain Dimerisation2 PF16864.5 EPS34232.1 - 0.0061 16.5 0.0 0.018 15.0 0.0 1.8 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_19 PF04672.12 EPS34232.1 - 0.026 14.0 0.0 0.042 13.3 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl methyltransferase Fungal_trans PF04082.18 EPS34233.1 - 1.6e-18 66.7 0.2 2.7e-18 66.0 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS34233.1 - 1.7e-08 34.4 4.6 3.2e-08 33.6 4.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.28 EPS34234.1 - 1.9e-80 270.5 0.1 5.8e-80 268.9 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme ketoacyl-synt PF00109.26 EPS34234.1 - 8.8e-68 228.6 0.0 2.4e-67 227.2 0.0 1.8 2 0 0 2 2 1 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.20 EPS34234.1 - 6.5e-64 216.3 0.0 3.5e-63 213.9 0.0 1.9 2 0 0 2 2 2 1 Condensation domain KR PF08659.10 EPS34234.1 - 2.3e-56 190.5 0.0 6.4e-56 189.1 0.0 1.8 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 EPS34234.1 - 2e-55 188.1 0.0 3.3e-55 187.4 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.21 EPS34234.1 - 3.3e-47 161.5 0.1 6.3e-47 160.6 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EPS34234.1 - 5.4e-33 113.5 0.0 1.3e-32 112.3 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 EPS34234.1 - 1.6e-20 73.3 0.0 6.5e-19 68.1 0.0 2.4 1 1 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.12 EPS34234.1 - 1.1e-19 70.9 0.0 4.4e-19 69.1 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EPS34234.1 - 3.2e-17 62.6 0.0 4.4e-09 36.6 0.0 3.0 3 0 0 3 3 2 2 Phosphopantetheine attachment site Methyltransf_25 PF13649.6 EPS34234.1 - 8.3e-15 55.3 0.0 6.7e-14 52.4 0.0 2.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPS34234.1 - 1.9e-14 53.9 0.0 5.2e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS34234.1 - 2.7e-13 50.4 0.0 4.1e-12 46.6 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EPS34234.1 - 3.7e-13 49.9 0.0 1e-12 48.5 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Epimerase PF01370.21 EPS34234.1 - 3.2e-11 43.1 0.0 1.8e-06 27.6 0.0 2.5 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Methyltransf_31 PF13847.6 EPS34234.1 - 7e-11 42.1 0.0 2e-09 37.4 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain adh_short PF00106.25 EPS34234.1 - 4.3e-10 39.4 0.0 1.6e-09 37.5 0.0 2.0 2 0 0 2 2 1 1 short chain dehydrogenase Ubie_methyltran PF01209.18 EPS34234.1 - 7.9e-07 28.6 0.0 1.1e-05 24.9 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family adh_short_C2 PF13561.6 EPS34234.1 - 2.8e-06 27.1 0.0 7.6e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase AMP-binding_C PF13193.6 EPS34234.1 - 0.00028 21.8 0.0 0.00095 20.1 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltransf_16 PF10294.9 EPS34234.1 - 0.0014 18.3 0.0 0.0032 17.2 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase Thiolase_N PF00108.23 EPS34234.1 - 0.0022 17.4 0.0 0.0043 16.4 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain GDP_Man_Dehyd PF16363.5 EPS34234.1 - 0.005 16.3 0.0 0.0081 15.6 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RrnaAD PF00398.20 EPS34234.1 - 0.0091 15.1 0.0 0.023 13.8 0.0 1.6 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase ACP_syn_III PF08545.10 EPS34234.1 - 0.084 12.7 0.6 0.57 10.1 0.2 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_33 PF10017.9 EPS34234.1 - 0.085 12.0 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent C9orf72-like PF15019.6 EPS34234.1 - 0.14 11.7 0.1 0.36 10.3 0.1 1.6 1 0 0 1 1 1 0 C9orf72-like protein family p450 PF00067.22 EPS34235.1 - 3.7e-45 154.5 0.0 4.6e-45 154.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.19 EPS34236.1 - 7e-64 216.3 0.0 9.6e-64 215.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EPS34236.1 - 0.00015 21.5 0.2 0.0034 17.0 0.4 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EPS34236.1 - 0.00016 21.8 0.3 0.00051 20.2 0.1 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EPS34236.1 - 0.0005 19.4 0.0 0.0012 18.2 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EPS34236.1 - 0.00091 18.6 0.0 0.0015 17.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EPS34236.1 - 0.0049 15.6 1.2 0.0098 14.6 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 EPS34236.1 - 0.0057 15.9 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 EPS34236.1 - 0.012 16.1 0.0 0.027 15.0 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EPS34236.1 - 0.025 15.0 0.0 0.072 13.5 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 EPS34236.1 - 0.026 13.8 0.0 0.057 12.7 0.0 1.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 EPS34236.1 - 0.031 13.1 0.2 0.15 10.9 0.3 1.9 1 1 0 2 2 2 0 Tryptophan halogenase FAD_binding_2 PF00890.24 EPS34236.1 - 0.04 13.0 0.2 0.15 11.1 0.1 2.0 3 0 0 3 3 3 0 FAD binding domain Glu_dehyd_C PF16912.5 EPS34236.1 - 0.045 13.2 0.0 0.077 12.5 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus FAD_oxidored PF12831.7 EPS34236.1 - 0.05 12.9 0.1 0.076 12.3 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase ThiF PF00899.21 EPS34236.1 - 0.15 11.4 0.1 0.24 10.7 0.1 1.2 1 0 0 1 1 1 0 ThiF family ADH_zinc_N PF00107.26 EPS34237.1 - 2.4e-06 27.6 0.0 8.6e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EPS34237.1 - 0.00017 21.4 0.0 0.0028 17.5 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EPS34237.1 - 0.027 14.3 0.0 0.15 12.0 0.0 2.0 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase p450 PF00067.22 EPS34238.1 - 3.4e-26 92.0 0.0 5.9e-25 87.9 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 Hexapep PF00132.24 EPS34239.1 - 3.3e-15 55.1 10.1 2.9e-12 45.8 1.3 4.1 4 0 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EPS34239.1 - 2.1e-14 52.9 10.1 5.6e-11 42.0 0.8 3.4 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.8 EPS34239.1 - 8.6e-13 48.3 0.1 1.4e-12 47.7 0.1 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase F-box PF00646.33 EPS34240.1 - 8.6e-06 25.5 0.1 2.2e-05 24.2 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EPS34240.1 - 0.00043 20.1 0.0 0.0012 18.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like zf-P11 PF03854.14 EPS34240.1 - 8.9 6.1 7.2 0.32 10.7 0.3 2.2 3 0 0 3 3 3 0 P-11 zinc finger Mito_carr PF00153.27 EPS34241.1 - 4.5e-60 199.6 2.6 5.4e-19 67.9 0.6 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EPS34241.1 - 0.34 10.0 1.1 0.98 8.5 0.2 2.1 2 1 1 3 3 3 0 Gammaproteobacterial serine protease TPK_catalytic PF04263.16 EPS34243.1 - 3.9e-33 114.1 0.1 6.4e-33 113.3 0.1 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 EPS34243.1 - 2.2e-20 72.1 0.0 3.6e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain DUF725 PF05267.12 EPS34243.1 - 0.081 12.9 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF725) Prismane PF03063.20 EPS34243.1 - 0.22 10.2 0.0 0.27 9.9 0.0 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family CHCH PF06747.13 EPS34244.1 - 9.7e-08 32.0 4.5 1.6e-07 31.2 4.5 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 EPS34244.1 - 0.00031 21.1 1.7 0.00056 20.3 1.7 1.4 1 0 0 1 1 1 1 GCK domain Death PF00531.22 EPS34244.1 - 0.014 15.6 0.0 0.021 15.0 0.0 1.3 1 0 0 1 1 1 0 Death domain PKD_channel PF08016.12 EPS34245.1 - 0.13 11.0 8.8 0.58 8.8 2.0 2.3 2 0 0 2 2 2 0 Polycystin cation channel S4 PF01479.25 EPS34246.1 - 6.7e-13 48.1 1.0 6.7e-13 48.1 1.0 3.0 3 0 0 3 3 3 1 S4 domain Ribosomal_S4 PF00163.19 EPS34246.1 - 7.9e-07 29.9 0.3 1.3e-06 29.2 0.2 1.6 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain KASH PF10541.9 EPS34247.1 - 0.12 12.7 1.8 8.9 6.7 0.1 2.4 2 0 0 2 2 2 0 Nuclear envelope localisation domain MARVEL PF01284.23 EPS34247.1 - 0.69 9.9 12.1 1.4 8.9 12.1 1.5 1 1 0 1 1 1 0 Membrane-associating domain FAD_binding_4 PF01565.23 EPS34248.1 - 2.5e-20 72.7 2.4 5.1e-20 71.6 2.4 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EPS34248.1 - 1.2e-07 31.7 0.2 2.4e-07 30.7 0.2 1.4 1 0 0 1 1 1 1 Berberine and berberine like Mito_carr PF00153.27 EPS34249.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial carrier protein MIF4G PF02854.19 EPS34250.1 - 9.7e-58 195.3 0.0 1.6e-33 116.2 0.0 3.5 3 0 0 3 3 3 2 MIF4G domain Upf2 PF04050.14 EPS34250.1 - 6.3e-43 146.8 10.6 6.3e-43 146.8 10.6 3.5 3 0 0 3 3 3 1 Up-frameshift suppressor 2 SUN PF03856.13 EPS34254.1 - 2.1e-91 305.7 10.1 3e-91 305.3 10.1 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) APH PF01636.23 EPS34256.1 - 1.3e-08 35.1 0.0 1.9e-07 31.3 0.0 2.0 2 0 0 2 2 2 2 Phosphotransferase enzyme family Ribosomal_L1 PF00687.21 EPS34257.1 - 6e-60 202.5 3.6 6e-60 202.5 3.6 1.5 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family ETF PF01012.21 EPS34258.1 - 1.6e-43 148.7 1.3 2.9e-43 147.9 1.3 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 EPS34258.1 - 9.2e-33 112.1 0.1 1.8e-32 111.2 0.1 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Aldo_ket_red PF00248.21 EPS34259.1 - 3.1e-61 207.1 0.0 3.8e-61 206.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AAA PF00004.29 EPS34260.1 - 2.4e-11 44.2 0.0 6.9e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EPS34260.1 - 3.5e-06 27.3 0.0 9.2e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 EPS34260.1 - 4e-05 23.6 0.2 0.00016 21.6 0.0 1.9 2 0 0 2 2 2 1 Rad17 P-loop domain RuvB_N PF05496.12 EPS34260.1 - 7.2e-05 22.6 0.0 0.00013 21.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EPS34260.1 - 0.00015 21.7 0.0 0.00032 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EPS34260.1 - 0.00072 19.7 0.0 0.0019 18.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EPS34260.1 - 0.0017 18.8 0.1 0.0088 16.4 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 EPS34260.1 - 0.016 15.3 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EPS34260.1 - 0.046 13.1 0.1 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 EPS34260.1 - 0.057 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TIP49 PF06068.13 EPS34260.1 - 0.066 12.4 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain RsgA_GTPase PF03193.16 EPS34260.1 - 0.084 12.8 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_24 PF13479.6 EPS34260.1 - 0.088 12.5 0.0 0.24 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EPS34260.1 - 0.11 11.8 0.0 0.24 10.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 EPS34260.1 - 0.12 12.9 0.0 0.44 11.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EPS34260.1 - 0.16 11.1 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain SprA-related PF12118.8 EPS34261.1 - 0.13 11.3 3.0 0.12 11.4 3.0 1.0 1 0 0 1 1 1 0 SprA-related family Herpes_capsid PF06112.11 EPS34261.1 - 1 9.4 7.4 1.3 9.1 7.4 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein SR-25 PF10500.9 EPS34261.1 - 1.4 8.5 10.3 1.6 8.3 10.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cellulase PF00150.18 EPS34262.1 - 3.2e-57 194.1 2.0 4.4e-57 193.7 2.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.18 EPS34262.1 - 7.7e-13 48.2 9.5 7.7e-13 48.2 9.5 3.0 2 0 0 2 2 2 1 Fungal cellulose binding domain Fungal_trans PF04082.18 EPS34263.1 - 1.1e-09 37.7 1.5 1.6e-09 37.2 1.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.16 EPS34264.1 - 5.6e-42 143.9 42.3 5.6e-42 143.9 42.3 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Neurensin PF14927.6 EPS34264.1 - 1.3 8.8 6.3 6.4 6.5 0.0 3.5 3 1 0 3 3 3 0 Neurensin FAD_binding_3 PF01494.19 EPS34265.1 - 2.2e-13 50.2 0.3 2.6e-12 46.7 0.3 2.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EPS34265.1 - 3.5e-08 33.4 1.5 0.0067 16.0 0.4 3.1 1 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EPS34265.1 - 3.2e-07 29.9 0.2 0.002 17.5 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EPS34265.1 - 0.00042 19.1 0.0 0.0063 15.3 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 EPS34265.1 - 0.0018 17.4 0.1 0.003 16.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EPS34265.1 - 0.0025 17.1 0.2 0.016 14.5 0.1 1.8 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EPS34265.1 - 0.036 13.1 0.2 0.073 12.1 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.7 EPS34265.1 - 0.037 13.4 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EPS34265.1 - 0.039 14.2 0.0 0.1 12.8 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EPS34265.1 - 0.061 12.5 0.1 0.52 9.5 0.1 2.0 2 0 0 2 2 2 0 Thi4 family p450 PF00067.22 EPS34266.1 - 1.1e-31 110.1 0.0 1.7e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 EPS34267.1 - 7.4e-23 81.0 0.0 1e-22 80.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS34267.1 - 9.8e-18 64.6 0.0 1.2e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EPS34267.1 - 1.6e-07 31.0 0.0 2.8e-06 27.0 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EPS34267.1 - 1.1e-06 28.7 0.0 1.9e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EPS34267.1 - 0.00021 20.8 0.0 0.15 11.4 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EPS34267.1 - 0.0076 16.2 0.1 0.02 14.8 0.1 1.7 1 1 0 1 1 1 1 NAD(P)H-binding EthD PF07110.11 EPS34268.1 - 4.8e-20 72.5 0.3 6e-20 72.2 0.3 1.1 1 0 0 1 1 1 1 EthD domain MmlI PF09448.10 EPS34268.1 - 0.0054 17.2 0.1 0.008 16.6 0.1 1.3 1 0 0 1 1 1 1 Methylmuconolactone methyl-isomerase Ribosomal_L26 PF16906.5 EPS34268.1 - 0.034 14.6 0.0 0.044 14.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal proteins L26 eukaryotic, L24P archaeal Imm9 PF15587.6 EPS34268.1 - 0.066 12.9 0.0 0.086 12.5 0.0 1.1 1 0 0 1 1 1 0 Immunity protein 9 Questin_oxidase PF14027.6 EPS34269.1 - 3.4e-91 306.3 0.4 4e-91 306.1 0.4 1.1 1 0 0 1 1 1 1 Questin oxidase-like NAD_binding_10 PF13460.6 EPS34270.1 - 9.7e-15 54.9 0.0 1.4e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EPS34270.1 - 1.8e-07 31.0 0.0 2.6e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 EPS34270.1 - 0.0026 16.8 0.1 0.0035 16.4 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EPS34270.1 - 0.043 13.0 0.0 0.097 11.8 0.0 1.6 2 0 0 2 2 2 0 Male sterility protein KR PF08659.10 EPS34270.1 - 0.089 12.7 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.15 EPS34270.1 - 0.11 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 EPS34270.1 - 0.15 12.5 0.0 0.29 11.6 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 EPS34270.1 - 0.16 11.4 0.1 0.25 10.7 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family HSP20 PF00011.21 EPS34271.1 - 0.0015 18.6 0.4 0.17 12.1 0.1 2.2 1 1 1 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EPS34271.1 - 0.22 11.1 0.1 5.7 6.6 0.0 2.1 2 0 0 2 2 2 0 HSP20-like domain found in ArsA Scytalone_dh PF02982.14 EPS34272.1 - 4.6e-71 237.8 0.2 5.2e-71 237.6 0.2 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.6 EPS34272.1 - 0.00019 21.6 0.5 0.00025 21.2 0.5 1.2 1 0 0 1 1 1 1 SnoaL-like domain ketoacyl-synt PF00109.26 EPS34273.1 - 1.1e-71 241.4 0.1 1.9e-71 240.6 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 EPS34273.1 - 5.3e-54 183.5 0.3 7.6e-52 176.4 0.1 2.7 2 0 0 2 2 2 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 EPS34273.1 - 9.7e-45 153.4 0.0 1.1e-43 149.9 0.0 2.4 2 1 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EPS34273.1 - 4.8e-34 116.9 1.0 1.1e-33 115.8 1.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 EPS34273.1 - 1.5e-11 44.4 1.4 2.8e-11 43.6 0.4 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site PS-DH PF14765.6 EPS34273.1 - 5.1e-10 39.1 0.0 8.9e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EPS34273.1 - 7.2e-08 32.9 0.0 1.9e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 EPS34273.1 - 0.00032 20.1 0.1 0.00072 19.0 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Lactamase_B PF00753.27 EPS34274.1 - 7.5e-16 58.7 5.3 1.8e-14 54.2 5.3 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EPS34274.1 - 1.1e-05 25.0 0.4 2.3e-05 24.0 0.4 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain BLACT_WH PF17778.1 EPS34274.1 - 0.0075 16.2 0.1 0.51 10.4 0.1 3.2 3 0 0 3 3 3 1 Beta-lactamase associated winged helix domain adh_short_C2 PF13561.6 EPS34275.1 - 2e-56 191.2 1.3 2.7e-56 190.7 1.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPS34275.1 - 9.5e-51 172.0 2.3 1.1e-50 171.8 2.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPS34275.1 - 5.1e-16 59.1 0.9 6.5e-16 58.7 0.9 1.1 1 0 0 1 1 1 1 KR domain DUF460 PF04312.13 EPS34275.1 - 0.0035 17.1 0.1 0.0092 15.7 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF460) DUF1776 PF08643.10 EPS34275.1 - 0.0036 16.7 0.0 0.0043 16.5 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EPS34275.1 - 0.0038 16.7 0.2 0.0068 15.9 0.2 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Peripla_BP_6 PF13458.6 EPS34275.1 - 0.062 12.9 0.5 0.19 11.3 0.2 1.8 2 0 0 2 2 2 0 Periplasmic binding protein THF_DHG_CYH_C PF02882.19 EPS34275.1 - 0.077 12.3 0.3 0.32 10.3 0.0 2.0 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SnoaL_2 PF12680.7 EPS34276.1 - 0.0016 19.0 0.0 0.0023 18.5 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain Methyltransf_11 PF08241.12 EPS34278.1 - 7.5e-14 52.2 0.0 1.4e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPS34278.1 - 5.3e-10 39.9 0.0 1e-09 39.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPS34278.1 - 1.1e-09 38.2 0.0 1.7e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPS34278.1 - 9.9e-07 29.4 0.0 1.6e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EPS34278.1 - 9.3e-06 25.6 0.0 1.3e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 EPS34278.1 - 0.0012 18.0 0.0 0.0017 17.5 0.0 1.1 1 0 0 1 1 1 1 DREV methyltransferase Ubie_methyltran PF01209.18 EPS34278.1 - 0.03 13.7 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family AflR PF08493.10 EPS34279.1 - 4.9e-24 85.3 10.5 7.5e-24 84.7 10.5 1.2 1 0 0 1 1 1 1 Aflatoxin regulatory protein Zn_clus PF00172.18 EPS34279.1 - 8.6e-06 25.8 10.6 2.4e-05 24.4 10.6 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain H_lectin PF09458.10 EPS34283.1 - 0.018 15.2 0.2 0.064 13.4 0.0 2.0 2 0 0 2 2 2 0 H-type lectin domain Nepo_coat_N PF03689.15 EPS34283.1 - 0.027 14.4 0.0 0.045 13.7 0.0 1.4 1 0 0 1 1 1 0 Nepovirus coat protein, N-terminal domain SKG6 PF08693.10 EPS34284.1 - 3.8e-06 26.2 0.4 3.8e-06 26.2 0.4 2.3 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Keratin_B2 PF01500.17 EPS34284.1 - 0.014 15.4 1.6 0.022 14.8 1.6 1.3 1 0 0 1 1 1 0 Keratin, high sulfur B2 protein Rax2 PF12768.7 EPS34284.1 - 0.075 12.5 4.2 0.15 11.5 0.4 1.9 1 1 1 2 2 2 0 Cortical protein marker for cell polarity PGF-CTERM PF18204.1 EPS34284.1 - 0.17 11.9 1.8 0.3 11.1 1.8 1.5 1 0 0 1 1 1 0 PGF-CTERM motif DUF347 PF03988.12 EPS34284.1 - 0.17 12.1 6.4 0.53 10.5 0.6 2.4 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) HRG PF16954.5 EPS34284.1 - 0.21 12.0 1.2 0.69 10.4 0.0 2.2 2 0 0 2 2 2 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene PRR18 PF15671.5 EPS34284.1 - 1.2 9.0 8.4 1.1 9.1 7.5 1.4 1 1 0 1 1 1 0 Proline-rich protein family 18 Glyco_hydro_47 PF01532.20 EPS34285.1 - 9e-166 552.3 0.0 1e-165 552.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Mannosyl_trans3 PF11051.8 EPS34287.1 - 0.025 13.9 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative GST_N PF02798.20 EPS34289.1 - 5.5e-16 58.7 0.0 1.1e-15 57.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EPS34289.1 - 8.5e-13 48.5 0.0 1.4e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EPS34289.1 - 1.3e-12 47.8 0.0 2.2e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EPS34289.1 - 5.7e-10 39.3 0.0 9.5e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EPS34289.1 - 3.5e-09 36.7 0.0 5.5e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EPS34289.1 - 8.3e-06 25.7 0.1 1.7e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SWIRM PF04433.17 EPS34290.1 - 7.8e-32 109.5 0.1 2e-31 108.2 0.1 1.7 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 EPS34290.1 - 4.8e-30 103.4 10.8 9.4e-30 102.4 10.8 1.5 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 EPS34290.1 - 2.6e-09 37.1 0.0 6.4e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EPS34290.1 - 1.9e-06 28.0 0.0 4.3e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 EPS34290.1 - 0.25 11.2 2.4 0.42 10.5 0.1 2.1 2 0 0 2 2 2 0 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 EPS34291.1 - 0.084 13.1 0.0 0.26 11.5 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain ResIII PF04851.15 EPS34292.1 - 7.9e-25 87.8 0.0 1.3e-23 83.9 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EPS34292.1 - 1.6e-14 54.2 0.5 1.5e-13 51.0 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 EPS34292.1 - 3.4e-08 33.5 0.0 7.5e-08 32.3 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EPS34292.1 - 2e-05 24.4 0.0 4.1e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 EPS34292.1 - 0.00095 18.5 0.0 0.0019 17.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Protamine_like PF06382.11 EPS34292.1 - 0.1 12.8 2.1 0.16 12.2 0.3 2.1 3 0 0 3 3 3 0 Protamine and protamine like SwrA PF17423.2 EPS34292.1 - 0.16 12.0 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Swarming motility protein ABC_tran PF00005.27 EPS34293.1 - 5.2e-47 159.8 0.1 3.4e-24 85.9 0.0 3.7 2 2 0 2 2 2 2 ABC transporter 4HB PF17947.1 EPS34293.1 - 2.1e-28 98.2 0.3 7.1e-28 96.5 0.3 2.0 1 0 0 1 1 1 1 Four helical bundle domain AAA_21 PF13304.6 EPS34293.1 - 4e-15 56.4 0.0 0.0022 17.8 0.0 4.7 5 0 0 5 5 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EPS34293.1 - 1.3e-13 50.9 0.1 4e-05 23.2 0.0 3.9 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EPS34293.1 - 2.2e-09 38.1 2.8 0.00043 20.8 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.6 EPS34293.1 - 4.7e-08 32.7 0.1 0.0086 15.8 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 EPS34293.1 - 6.7e-07 29.7 0.0 0.038 14.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain PduV-EutP PF10662.9 EPS34293.1 - 1.5e-06 28.0 0.0 0.067 12.9 0.0 2.9 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 EPS34293.1 - 3.8e-06 26.9 0.1 0.0033 17.4 0.0 2.8 3 0 0 3 3 2 1 RsgA GTPase AAA PF00004.29 EPS34293.1 - 5.7e-06 26.8 0.0 0.24 11.9 0.0 4.4 4 1 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EPS34293.1 - 6.1e-06 26.7 0.0 0.086 13.2 0.0 3.4 3 1 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.6 EPS34293.1 - 9.4e-06 25.9 0.0 0.1 12.9 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.6 EPS34293.1 - 1.1e-05 26.0 0.0 0.16 12.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EPS34293.1 - 1.1e-05 25.5 0.0 0.0061 16.6 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 EPS34293.1 - 0.00012 22.4 0.0 0.82 10.1 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_15 PF13175.6 EPS34293.1 - 0.00017 21.5 0.1 1.2 8.8 0.0 3.3 4 0 0 4 4 3 2 AAA ATPase domain AAA_14 PF13173.6 EPS34293.1 - 0.0002 21.4 0.0 0.77 9.8 0.0 3.6 4 0 0 4 4 2 1 AAA domain NACHT PF05729.12 EPS34293.1 - 0.00031 20.7 0.0 0.2 11.6 0.0 2.5 2 0 0 2 2 2 1 NACHT domain DUF87 PF01935.17 EPS34293.1 - 0.00032 20.9 0.1 0.19 11.8 0.0 3.0 3 0 0 3 3 2 1 Helicase HerA, central domain AAA_27 PF13514.6 EPS34293.1 - 0.00045 19.9 0.0 0.41 10.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 EPS34293.1 - 0.0006 19.6 0.0 1.6 8.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.23 EPS34293.1 - 0.0007 19.7 0.0 0.0036 17.4 0.0 2.3 2 0 0 2 2 1 1 Dynamin family AAA_33 PF13671.6 EPS34293.1 - 0.0011 19.1 0.0 1.3 9.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain HEAT_2 PF13646.6 EPS34293.1 - 0.0012 19.2 0.1 0.56 10.6 0.1 3.3 2 1 1 3 3 2 1 HEAT repeats AAA_30 PF13604.6 EPS34293.1 - 0.0012 18.6 0.0 1 9.0 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_13 PF13166.6 EPS34293.1 - 0.0013 17.5 0.1 0.48 9.0 0.0 3.2 4 0 0 4 4 4 1 AAA domain G-alpha PF00503.20 EPS34293.1 - 0.0016 17.7 0.0 1.9 7.6 0.0 2.7 2 0 0 2 2 2 2 G-protein alpha subunit cobW PF02492.19 EPS34293.1 - 0.0023 17.6 0.2 1.7 8.2 0.0 3.3 4 0 0 4 4 3 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EPS34293.1 - 0.0038 16.3 0.1 1.5 7.8 0.0 2.4 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 EPS34293.1 - 0.005 16.1 0.1 0.13 11.4 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain ATP_bind_1 PF03029.17 EPS34293.1 - 0.0051 16.6 0.0 4.1 7.1 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ATPase_2 PF01637.18 EPS34293.1 - 0.0056 16.6 0.0 0.87 9.4 0.0 2.9 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea HEAT PF02985.22 EPS34293.1 - 0.0057 16.8 0.2 3.8 8.0 0.0 4.6 4 0 0 4 4 4 0 HEAT repeat HEAT_EZ PF13513.6 EPS34293.1 - 0.0076 16.7 5.0 16 6.1 0.0 4.8 4 1 1 5 5 4 0 HEAT-like repeat SbcCD_C PF13558.6 EPS34293.1 - 0.008 16.4 0.0 3.3 8.0 0.0 3.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Roc PF08477.13 EPS34293.1 - 0.01 16.1 0.0 7.7 6.8 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase CLP1_P PF16575.5 EPS34293.1 - 0.013 15.3 0.6 2.8 7.7 0.0 3.6 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop TsaE PF02367.17 EPS34293.1 - 0.016 15.2 0.1 7.3 6.6 0.0 3.3 3 0 0 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 EPS34293.1 - 0.027 14.0 0.0 2.1 7.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EPS34293.1 - 0.032 14.2 0.0 16 5.5 0.0 3.5 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.25 EPS34293.1 - 0.037 13.7 0.0 3.1 7.4 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Mg_chelatase PF01078.21 EPS34293.1 - 0.048 13.0 0.0 4.6 6.6 0.0 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 EPS34293.1 - 0.05 12.7 0.1 7.3 5.6 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 EPS34293.1 - 0.05 13.0 0.5 6.1 6.1 0.0 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_7 PF12775.7 EPS34293.1 - 0.055 13.0 0.0 7.7 6.0 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 EPS34293.1 - 0.066 12.9 0.0 15 5.3 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein Adaptin_N PF01602.20 EPS34293.1 - 0.091 11.3 0.1 1.3 7.5 0.0 2.1 1 1 1 2 2 2 0 Adaptin N terminal region NTPase_1 PF03266.15 EPS34293.1 - 0.097 12.6 0.1 18 5.2 0.1 2.9 2 0 0 2 2 2 0 NTPase Septin PF00735.18 EPS34293.1 - 0.1 11.9 0.0 4.3 6.5 0.0 2.4 2 0 0 2 2 2 0 Septin ParcG PF10274.9 EPS34293.1 - 0.11 12.6 0.2 4.1 7.5 0.0 2.9 1 1 2 3 3 3 0 Parkin co-regulated protein Arf PF00025.21 EPS34293.1 - 0.14 11.6 0.1 14 5.1 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family Rad17 PF03215.15 EPS34293.1 - 0.14 12.0 0.0 2.9 7.8 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain COX7B PF05392.11 EPS34294.1 - 0.1 12.3 0.7 0.15 11.8 0.2 1.5 2 0 0 2 2 2 0 Cytochrome C oxidase chain VIIB YkuD PF03734.14 EPS34294.1 - 0.13 12.7 0.0 0.14 12.5 0.0 1.2 1 0 0 1 1 1 0 L,D-transpeptidase catalytic domain PGAP1 PF07819.13 EPS34296.1 - 1.1e-89 300.1 0.1 1.9e-89 299.4 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 EPS34296.1 - 2e-06 28.5 0.1 5.1e-06 27.3 0.1 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 EPS34296.1 - 0.0011 18.9 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.20 EPS34296.1 - 0.0035 17.0 0.0 0.0098 15.6 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.15 EPS34296.1 - 0.0038 16.5 0.0 0.006 15.8 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Esterase PF00756.20 EPS34296.1 - 0.0046 16.6 0.0 0.039 13.6 0.0 2.0 2 0 0 2 2 2 1 Putative esterase Hydrolase_4 PF12146.8 EPS34296.1 - 0.0054 16.0 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 EPS34296.1 - 0.045 13.3 0.0 0.078 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_3 PF07859.13 EPS34296.1 - 0.1 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Sugar_tr PF00083.24 EPS34297.1 - 4.2e-35 121.5 22.6 2.5e-34 118.9 22.6 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS34297.1 - 3.6e-29 101.8 48.6 1e-27 97.0 31.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Abhydrolase_9_N PF15420.6 EPS34297.1 - 0.024 14.6 1.1 0.024 14.6 1.1 2.3 3 0 0 3 3 3 0 Alpha/beta-hydrolase family N-terminus DUF3824 PF12868.7 EPS34300.1 - 0.0026 18.4 2.5 0.0026 18.4 2.5 3.3 2 1 0 2 2 2 1 Domain of unknwon function (DUF3824) DUF533 PF04391.12 EPS34300.1 - 0.0075 15.9 3.0 0.017 14.7 3.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF533) SR-25 PF10500.9 EPS34300.1 - 0.043 13.4 15.9 0.058 13.0 15.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Rick_17kDa_Anti PF05433.15 EPS34300.1 - 0.065 13.1 21.6 0.16 11.9 21.6 1.7 1 0 0 1 1 1 0 Glycine zipper 2TM domain DUF755 PF05501.11 EPS34300.1 - 0.53 10.6 23.9 0.89 9.8 23.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Dehydrin PF00257.19 EPS34300.1 - 4.4 7.8 21.5 14 6.2 21.5 2.1 1 1 0 1 1 1 0 Dehydrin AP3D1 PF06375.11 EPS34300.1 - 5.6 7.2 11.8 8.3 6.6 11.8 1.2 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 Complex1_LYR PF05347.15 EPS34301.1 - 0.055 13.5 1.2 0.12 12.4 1.2 1.7 1 0 0 1 1 1 0 Complex 1 protein (LYR family) VWA_CoxE PF05762.14 EPS34301.1 - 0.077 12.4 0.8 0.16 11.4 0.8 1.4 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Ank_4 PF13637.6 EPS34302.1 - 3.1e-12 46.8 0.9 4.8e-09 36.6 0.2 3.9 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EPS34302.1 - 6.5e-07 29.9 0.1 0.0025 18.4 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EPS34302.1 - 0.00059 20.1 2.6 0.17 12.5 0.1 4.4 4 1 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 EPS34302.1 - 0.00078 19.7 1.2 0.032 14.6 0.2 3.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) KilA-N PF04383.13 EPS34302.1 - 0.0042 16.9 0.4 0.044 13.6 0.4 2.5 1 1 0 1 1 1 1 KilA-N domain Baculo_PEP_C PF04513.12 EPS34302.1 - 0.19 11.8 0.7 0.45 10.6 0.7 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus HAUS-augmin3 PF14932.6 EPS34302.1 - 0.2 11.2 6.8 0.039 13.5 3.0 1.7 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Ank PF00023.30 EPS34302.1 - 1.2 9.8 4.5 17 6.1 0.2 3.7 3 0 0 3 3 3 0 Ankyrin repeat Cellulase PF00150.18 EPS34303.1 - 4.6e-32 111.6 3.4 1.2e-31 110.2 1.4 2.0 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) TPR_2 PF07719.17 EPS34304.1 - 1.3e-05 24.9 1.4 0.017 15.2 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EPS34304.1 - 6.3e-05 22.6 0.7 0.013 15.3 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EPS34304.1 - 0.002 18.2 0.4 0.56 10.6 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EPS34304.1 - 0.0033 17.1 0.0 0.35 10.6 0.0 3.1 2 1 1 3 3 3 1 TPR repeat TPR_7 PF13176.6 EPS34304.1 - 0.018 15.1 1.2 1.6 9.0 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 EPS34304.1 - 0.076 13.4 0.0 2.9 8.5 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2547 PF10818.8 EPS34304.1 - 0.17 12.8 0.6 0.62 11.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2547) TPR_19 PF14559.6 EPS34304.1 - 0.67 10.5 7.7 0.89 10.1 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 EPS34304.1 - 6.7 7.1 8.6 3.9 7.8 0.0 4.1 3 2 1 4 4 4 0 Tetratricopeptide repeat Methyltransf_10 PF05971.12 EPS34305.1 - 1.4e-65 221.5 0.0 2.1e-65 221.0 0.0 1.1 1 0 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 EPS34305.1 - 4.9e-06 26.2 0.0 9e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EPS34305.1 - 0.0003 21.4 0.0 0.00073 20.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EPS34305.1 - 0.0024 17.2 0.0 0.0042 16.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 EPS34305.1 - 0.0042 16.5 0.0 0.0068 15.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.18 EPS34305.1 - 0.0055 16.4 0.0 0.0091 15.7 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.6 EPS34305.1 - 0.007 16.2 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EPS34305.1 - 0.0097 15.8 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS34305.1 - 0.025 15.2 0.0 0.055 14.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain TrmK PF04816.12 EPS34305.1 - 0.094 12.2 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase ADC PF06314.11 EPS34305.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Acetoacetate decarboxylase (ADC) adh_short_C2 PF13561.6 EPS34306.1 - 4.6e-50 170.4 0.2 5.7e-50 170.0 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPS34306.1 - 1.1e-41 142.5 0.1 1.3e-41 142.3 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPS34306.1 - 2.3e-14 53.7 0.7 3.1e-14 53.3 0.7 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPS34306.1 - 0.0002 20.9 0.1 0.00037 20.0 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EPS34306.1 - 0.011 15.1 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Methyltransf_11 PF08241.12 EPS34306.1 - 0.084 13.5 0.0 0.2 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain zf-LITAF-like PF10601.9 EPS34307.1 - 1.8e-19 69.8 20.9 2.4e-19 69.4 20.9 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Cys_rich_KTR PF14205.6 EPS34307.1 - 2.8 7.8 8.5 11 5.9 3.8 2.4 1 1 0 2 2 2 0 Cysteine-rich KTR MFS_1 PF07690.16 EPS34308.1 - 3.3e-44 151.3 35.4 4e-39 134.5 25.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS34308.1 - 1.6e-11 43.8 11.2 1.6e-11 43.8 11.2 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.13 EPS34308.1 - 1.4e-05 23.7 8.4 2.8e-05 22.8 8.4 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Na_H_Exchanger PF00999.21 EPS34309.1 - 2.5e-31 108.8 36.0 3.6e-24 85.3 27.0 3.0 3 0 0 3 3 3 3 Sodium/hydrogen exchanger family YqhR PF11085.8 EPS34309.1 - 5.2 7.0 7.1 0.42 10.5 1.1 2.3 2 1 0 2 2 2 0 Conserved membrane protein YqhR ADH_zinc_N PF00107.26 EPS34310.1 - 6.6e-10 39.1 0.2 1.1e-09 38.3 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPS34310.1 - 1.5e-07 32.5 0.1 2.7e-07 31.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Acetyltransf_3 PF13302.7 EPS34311.1 - 1.1e-16 61.8 0.1 2.3e-16 60.7 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EPS34311.1 - 1.5e-10 41.4 0.0 2e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 EPS34311.1 - 2.8e-05 23.8 0.0 4.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPS34311.1 - 0.0024 17.8 0.0 0.0037 17.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EPS34311.1 - 0.14 12.6 0.0 0.23 11.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4602 PF15375.6 EPS34312.1 - 6.9e-15 55.6 15.0 6.9e-15 55.6 15.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4602) BSP_II PF05432.11 EPS34312.1 - 6.4 6.4 22.3 2 8.0 18.9 1.7 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) His_biosynth PF00977.21 EPS34313.1 - 1.1e-33 116.6 0.0 1.4e-33 116.3 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Esterase_phd PF10503.9 EPS34314.1 - 1e-23 84.0 1.0 1.7e-23 83.3 1.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.18 EPS34314.1 - 2.8e-13 49.6 14.6 2.8e-13 49.6 14.6 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain Peptidase_S9 PF00326.21 EPS34314.1 - 5e-12 45.7 1.7 9.9e-12 44.8 1.7 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 EPS34314.1 - 1.8e-05 24.5 1.3 1.8e-05 24.5 1.3 1.6 2 0 0 2 2 2 1 Putative esterase BAAT_C PF08840.11 EPS34314.1 - 0.00021 21.3 0.1 0.00035 20.6 0.1 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 EPS34314.1 - 0.0017 18.2 0.1 0.0025 17.7 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EPS34314.1 - 0.0077 16.1 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.18 EPS34314.1 - 0.0088 15.6 1.7 0.03 13.9 1.7 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family PAF-AH_p_II PF03403.13 EPS34314.1 - 0.18 10.3 0.1 0.3 9.6 0.1 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Toxin_7 PF05980.12 EPS34314.1 - 0.23 11.7 6.4 0.077 13.3 3.0 2.0 2 0 0 2 2 2 0 Toxin 7 Glyco_hydro_43 PF04616.14 EPS34315.1 - 1.2e-18 67.5 1.4 1.2e-18 67.5 1.4 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 MliC PF09864.9 EPS34315.1 - 0.023 14.6 0.4 0.069 13.1 0.1 1.9 2 0 0 2 2 2 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme Yip1 PF04893.17 EPS34316.1 - 0.0086 15.8 1.5 0.0098 15.6 1.5 1.1 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 EPS34316.1 - 0.015 15.1 0.5 0.018 14.9 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) Radical_SAM_C PF16199.5 EPS34317.1 - 9.5e-33 112.1 0.1 2.7e-32 110.6 0.0 1.8 2 0 0 2 2 2 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 EPS34317.1 - 2.6e-19 70.2 0.1 8.8e-19 68.5 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 EPS34317.1 - 1.5e-10 41.3 0.1 3e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EPS34317.1 - 3.8e-06 26.9 0.0 1.3e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EPS34317.1 - 0.077 13.0 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_7 PF13508.7 EPS34317.1 - 0.11 13.0 0.1 0.25 11.8 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CoA_binding PF02629.19 EPS34318.1 - 2.9e-27 95.2 3.2 5.3e-27 94.4 0.9 2.2 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 EPS34318.1 - 1.7e-22 79.9 0.1 3e-22 79.1 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 EPS34318.1 - 1.4e-07 31.4 0.0 2.5e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 EPS34318.1 - 0.00077 19.9 0.1 0.0027 18.2 0.1 1.9 2 0 0 2 2 2 1 CoA binding domain Isochorismatase PF00857.20 EPS34319.1 - 8.8e-18 65.1 0.0 5.6e-17 62.5 0.0 2.1 1 1 0 1 1 1 1 Isochorismatase family DUF3632 PF12311.8 EPS34320.1 - 3.7e-28 99.1 1.9 4.7e-28 98.8 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Glyco_hydro_28 PF00295.17 EPS34321.1 - 3.7e-51 174.1 9.3 5.2e-51 173.6 9.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 FA_desaturase PF00487.24 EPS34322.1 - 3.7e-12 46.6 24.1 3.7e-12 46.6 24.1 2.1 1 1 1 2 2 2 1 Fatty acid desaturase MFS_1 PF07690.16 EPS34323.1 - 4.3e-35 121.3 33.6 4.3e-35 121.3 33.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS34323.1 - 2.4e-09 36.6 23.0 1.6e-08 33.9 23.0 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter FA_desaturase PF00487.24 EPS34323.1 - 5.2 6.8 20.5 0.066 13.0 2.2 2.9 1 1 1 3 3 3 0 Fatty acid desaturase DUF455 PF04305.14 EPS34326.1 - 8.7e-98 326.8 0.0 1.1e-97 326.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.26 EPS34326.1 - 7.2e-06 25.9 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 EPS34326.1 - 9.5e-05 22.3 0.0 0.00025 20.9 0.0 1.7 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain MFS_1 PF07690.16 EPS34329.1 - 1.1e-34 119.9 30.2 1.7e-34 119.3 29.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Phage_holin_5_2 PF16079.5 EPS34329.1 - 0.15 12.4 7.0 19 5.6 0.1 4.4 2 2 1 4 4 4 0 Phage holin family Hol44, in holin superfamily V Orf78 PF06024.12 EPS34329.1 - 0.18 12.1 0.2 6.6 7.1 0.0 2.8 4 0 0 4 4 4 0 Orf78 (ac78) DUF4234 PF14018.6 EPS34329.1 - 0.66 10.1 5.2 2.9 8.1 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4234) RNA_pol_I_A49 PF06870.12 EPS34330.1 - 5.8e-71 239.4 0.0 1.6e-70 238.0 0.0 1.6 1 1 0 1 1 1 1 A49-like RNA polymerase I associated factor Aminotran_1_2 PF00155.21 EPS34331.1 - 2.4e-32 112.5 0.0 3.1e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EPS34331.1 - 3.7e-09 36.0 0.0 6.1e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EPS34331.1 - 1.1e-08 34.7 0.0 1.9e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EPS34331.1 - 1.2e-08 33.9 0.0 1.8e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.20 EPS34331.1 - 0.012 14.4 0.0 0.79 8.4 0.0 2.1 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, major domain Met_gamma_lyase PF06838.11 EPS34331.1 - 0.051 12.1 0.0 0.07 11.7 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase Aminotran_1_2 PF00155.21 EPS34332.1 - 1.4e-84 284.3 0.0 1.8e-84 284.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EPS34332.1 - 4.5e-06 26.2 0.3 9.3e-06 25.2 0.3 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EPS34332.1 - 1.1e-05 24.2 0.0 1.9e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EPS34332.1 - 0.00065 18.8 0.0 0.0013 17.8 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EPS34332.1 - 0.026 13.8 0.4 0.062 12.6 0.5 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase Preseq_ALAS PF09029.10 EPS34332.1 - 1.1 9.7 3.6 6.1 7.3 3.6 2.2 1 1 0 1 1 1 0 5-aminolevulinate synthase presequence SNF2_N PF00176.23 EPS34333.1 - 6.7e-65 219.1 1.9 1.6e-64 217.8 1.1 1.9 1 1 1 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.6 EPS34333.1 - 2.4e-49 167.1 22.9 2.4e-49 167.1 22.9 3.6 4 1 0 4 4 4 1 DNA-binding domain Helicase_C PF00271.31 EPS34333.1 - 2e-19 70.0 0.0 4.9e-19 68.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPS34333.1 - 4.8e-07 29.9 0.0 4.8e-07 29.9 0.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EPS34333.1 - 0.00061 19.6 0.0 0.0016 18.2 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Fe_hyd_lg_C PF02906.14 EPS34333.1 - 0.01 15.5 1.3 0.022 14.4 1.3 1.5 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain HDA2-3 PF11496.8 EPS34333.1 - 0.025 13.8 1.3 0.097 11.8 0.0 2.6 3 1 0 3 3 3 0 Class II histone deacetylase complex subunits 2 and 3 DUF2525 PF10733.9 EPS34333.1 - 0.072 13.4 1.3 0.62 10.4 0.1 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2525) ADH_N PF08240.12 EPS34335.1 - 3.3e-30 104.2 1.1 5.4e-30 103.5 1.1 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPS34335.1 - 1.4e-22 80.1 0.1 2.5e-22 79.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EPS34335.1 - 0.00012 23.2 0.0 0.00021 22.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EPS34335.1 - 0.0099 15.3 0.1 0.016 14.6 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.25 EPS34335.1 - 0.03 13.8 1.0 0.066 12.7 0.9 1.6 1 1 0 1 1 1 0 short chain dehydrogenase AlaDh_PNT_C PF01262.21 EPS34335.1 - 0.033 13.5 0.2 0.049 12.9 0.2 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Glucokinase PF02685.16 EPS34335.1 - 0.17 10.9 1.6 0.29 10.1 1.3 1.4 1 1 0 1 1 1 0 Glucokinase Aminotran_3 PF00202.21 EPS34337.1 - 2.2e-128 428.4 0.0 2.6e-128 428.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Spt4 PF06093.13 EPS34338.1 - 1.7e-31 108.1 0.3 2e-31 107.9 0.3 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger PPP5 PF08321.12 EPS34339.1 - 3.9e-34 116.8 0.1 8e-34 115.8 0.1 1.6 1 0 0 1 1 1 1 PPP5 TPR repeat region Metallophos PF00149.28 EPS34339.1 - 3.8e-30 105.9 0.0 5.9e-30 105.3 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_1 PF00515.28 EPS34339.1 - 5.3e-08 32.4 4.1 0.019 14.8 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EPS34339.1 - 1.7e-06 27.7 4.7 0.52 10.6 0.1 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 EPS34339.1 - 1e-05 25.9 0.8 0.057 13.9 0.0 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EPS34339.1 - 0.00022 20.8 2.5 0.073 12.8 0.1 3.4 3 0 0 3 3 3 1 TPR repeat TPR_9 PF13371.6 EPS34339.1 - 0.0029 17.7 0.1 0.069 13.3 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 EPS34339.1 - 0.0079 16.5 0.4 16 6.2 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EPS34339.1 - 0.014 16.0 0.9 0.78 10.5 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EPS34339.1 - 0.054 14.3 0.4 1.6 9.7 0.1 3.4 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 EPS34339.1 - 0.064 13.6 0.0 1.7 9.0 0.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF89 PF01937.19 EPS34340.1 - 2.3e-137 457.7 0.0 2.6e-137 457.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Cytochrom_C550 PF14495.6 EPS34340.1 - 0.006 16.3 0.0 1.3 8.8 0.0 2.6 3 0 0 3 3 3 2 Cytochrome c-550 domain Cut12 PF11500.8 EPS34341.1 - 3e-48 163.5 8.4 3e-48 163.5 8.4 4.7 3 1 0 3 3 3 1 Spindle pole body formation-associated protein Invasin_D3 PF09134.10 EPS34341.1 - 0.079 13.3 1.2 0.14 12.5 0.1 1.9 2 0 0 2 2 2 0 Invasin, domain 3 Fez1 PF06818.15 EPS34341.1 - 1.5 9.3 50.2 0.38 11.2 30.6 3.4 1 1 2 3 3 3 0 Fez1 DUF812 PF05667.11 EPS34341.1 - 1.8 7.3 42.1 2.9 6.7 42.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Lebercilin PF15619.6 EPS34341.1 - 2.9 7.5 55.4 1.4 8.5 27.4 2.7 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF2730 PF10805.8 EPS34341.1 - 4.8 7.3 16.4 0.99 9.5 0.7 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) HGTP_anticodon2 PF12745.7 EPS34342.1 - 2.4e-86 289.5 3.3 2.4e-86 289.5 3.3 1.8 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase PF00069.25 EPS34342.1 - 7.1e-69 232.1 0.0 3.2e-35 121.8 0.0 3.6 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 EPS34342.1 - 5.8e-38 130.7 0.0 1.1e-16 61.0 0.0 3.6 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 EPS34342.1 - 3.7e-17 62.7 0.4 1.2e-16 61.0 0.1 2.1 2 0 0 2 2 2 1 RWD domain tRNA-synt_His PF13393.6 EPS34342.1 - 3.1e-12 46.4 2.1 9.7e-12 44.8 0.0 2.5 3 0 0 3 3 3 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 EPS34342.1 - 0.00025 21.1 0.1 0.00089 19.4 0.1 2.0 1 0 0 1 1 1 1 Anticodon binding domain APH PF01636.23 EPS34342.1 - 0.0007 19.6 0.0 0.0007 19.6 0.0 2.9 3 0 0 3 3 3 1 Phosphotransferase enzyme family FTA2 PF13095.6 EPS34342.1 - 0.004 16.8 0.0 0.078 12.6 0.0 2.3 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Torus PF16131.5 EPS34343.1 - 2.5e-40 137.6 0.4 7.6e-40 136.0 0.1 2.0 2 0 0 2 2 2 1 Torus domain RRM_1 PF00076.22 EPS34343.1 - 2.1e-08 33.9 0.0 4.2e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EPS34343.1 - 0.0075 16.3 0.1 0.019 15.0 0.0 1.7 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.24 EPS34343.1 - 0.012 15.5 2.4 0.025 14.5 2.4 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EPS34343.1 - 0.022 14.8 3.0 0.039 14.0 3.0 1.4 1 0 0 1 1 1 0 Zinc finger domain RRM_5 PF13893.6 EPS34343.1 - 0.075 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MMR_HSR1_Xtn PF16897.5 EPS34344.1 - 4.8e-36 123.0 2.0 1.7e-35 121.2 0.5 2.1 2 0 0 2 2 2 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 EPS34344.1 - 1.3e-20 73.6 0.0 3e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 EPS34344.1 - 1.1e-18 67.0 0.0 2.3e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 EPS34344.1 - 2.1e-12 46.8 0.0 3.6e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EPS34344.1 - 4.6e-05 23.6 0.2 0.049 13.7 0.0 2.6 1 1 1 2 2 2 2 Dynamin family Peptidase_M23_N PF18421.1 EPS34344.1 - 0.022 14.6 0.0 0.068 13.1 0.0 1.8 2 0 0 2 2 2 0 Peptidase family M23 N-terminal domain MeaB PF03308.16 EPS34344.1 - 0.026 13.5 0.3 0.11 11.5 0.1 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MCM PF00493.23 EPS34344.1 - 0.034 13.2 0.1 0.073 12.1 0.0 1.5 2 0 0 2 2 2 0 MCM P-loop domain AIG1 PF04548.16 EPS34344.1 - 0.046 13.0 0.0 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 AIG1 family GATase PF00117.28 EPS34345.1 - 1.5e-46 158.5 0.0 2.2e-46 158.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 EPS34345.1 - 1.4e-45 154.2 0.0 2.6e-45 153.4 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.13 EPS34345.1 - 1.5e-05 24.9 0.3 0.00036 20.3 0.3 2.3 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.24 EPS34345.1 - 0.011 15.5 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family Zn_clus PF00172.18 EPS34346.1 - 8.2e-09 35.5 9.3 1.4e-08 34.7 9.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 EPS34346.1 - 1.3e-05 24.4 0.3 5e-05 22.5 0.0 1.9 1 1 1 2 2 2 1 Fungal specific transcription factor domain PIG-X PF08320.12 EPS34347.1 - 7.8e-69 231.8 0.0 1.1e-68 231.3 0.0 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 DnaJ_C PF01556.18 EPS34348.1 - 2.3e-32 112.1 0.4 2.9e-32 111.8 0.4 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EPS34348.1 - 1.8e-27 95.2 6.1 3.4e-27 94.4 6.1 1.5 1 0 0 1 1 1 1 DnaJ domain Malate_DH PF12434.8 EPS34348.1 - 0.026 14.6 0.1 0.06 13.4 0.1 1.6 1 0 0 1 1 1 0 Malate dehydrogenase enzyme Peptidase_S10 PF00450.22 EPS34349.1 - 8.8e-85 285.6 1.6 1.8e-84 284.6 1.6 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_1 PF00561.20 EPS34350.1 - 1.3e-16 61.1 0.1 2.2e-16 60.3 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPS34350.1 - 1.1e-11 45.8 8.6 1.4e-11 45.4 8.6 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPS34350.1 - 1.5e-09 37.4 0.3 6.2e-09 35.5 0.3 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 EPS34350.1 - 0.0073 16.2 0.2 0.014 15.3 0.2 1.6 1 1 0 1 1 1 1 Serine hydrolase Abhydrolase_4 PF08386.10 EPS34350.1 - 0.069 13.3 0.0 0.21 11.7 0.0 1.8 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_5 PF12695.7 EPS34350.1 - 0.11 12.3 0.0 0.75 9.5 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family Ndr PF03096.14 EPS34350.1 - 0.18 10.4 0.0 0.27 9.9 0.0 1.1 1 0 0 1 1 1 0 Ndr family MGC-24 PF05283.11 EPS34351.1 - 3.7 8.0 7.9 6.6 7.2 7.9 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Amidohydro_3 PF07969.11 EPS34352.1 - 4.9e-72 243.9 2.1 5.6e-72 243.7 2.1 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 EPS34352.1 - 6.7e-12 45.4 0.3 9.9e-07 28.4 0.0 2.7 2 1 0 2 2 2 2 Amidohydrolase family Glutaredoxin PF00462.24 EPS34352.1 - 0.18 12.1 0.0 0.44 10.8 0.0 1.7 1 0 0 1 1 1 0 Glutaredoxin STE PF02200.16 EPS34354.1 - 3.3e-56 188.4 0.1 5e-56 187.8 0.1 1.3 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.26 EPS34354.1 - 5.1e-11 42.4 9.9 1.9e-06 28.0 0.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EPS34354.1 - 9.6e-09 35.3 4.0 9.6e-09 35.3 4.0 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 EPS34354.1 - 1.1e-07 32.1 8.2 0.00093 19.8 0.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EPS34354.1 - 0.0015 18.5 4.5 0.0015 18.4 0.1 2.3 2 0 0 2 2 2 1 C2H2-type zinc finger NOA36 PF06524.12 EPS34354.1 - 0.035 13.4 0.3 0.059 12.7 0.3 1.2 1 0 0 1 1 1 0 NOA36 protein zf-C2H2_jaz PF12171.8 EPS34354.1 - 0.061 13.6 0.1 0.93 9.9 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.18 EPS34354.1 - 0.11 13.2 2.4 0.24 12.1 2.4 1.5 1 0 0 1 1 1 0 TRAF-type zinc finger zf-Di19 PF05605.12 EPS34354.1 - 0.23 11.8 2.9 0.61 10.4 2.9 1.7 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.6 EPS34354.1 - 0.8 9.5 7.9 9.3 6.1 0.2 3.0 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2HC_2 PF13913.6 EPS34354.1 - 1.7 8.6 5.3 2 8.4 0.3 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type MFS_1 PF07690.16 EPS34356.1 - 5.4e-27 94.6 35.6 5.4e-27 94.6 35.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EPS34357.1 - 4.7e-11 41.9 4.0 4.7e-11 41.9 4.0 2.4 2 1 0 2 2 2 1 MFS/sugar transport protein MFS_1 PF07690.16 EPS34357.1 - 1.7e-06 27.2 24.8 2.5e-05 23.4 14.5 2.6 2 0 0 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.15 EPS34357.1 - 0.00031 19.9 1.3 0.00057 19.0 1.3 1.4 1 0 0 1 1 1 1 PUCC protein DUF4190 PF13828.6 EPS34357.1 - 0.43 10.4 11.0 4.1 7.2 0.0 4.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4190) Na_H_Exchanger PF00999.21 EPS34358.1 - 6.3e-72 242.5 39.0 7.9e-72 242.1 39.0 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family PepSY_TM PF03929.16 EPS34358.1 - 0.19 11.4 2.0 0.6 9.7 2.0 2.0 1 1 0 1 1 1 0 PepSY-associated TM region PspC PF04024.12 EPS34358.1 - 4.2 7.3 6.2 0.87 9.4 1.4 2.4 2 0 0 2 2 2 0 PspC domain NiFe_hyd_3_EhaA PF17367.2 EPS34358.1 - 4.9 7.4 11.9 3.6 7.8 0.4 3.9 2 1 1 3 3 3 0 NiFe-hydrogenase-type-3 Eha complex subunit A AA_permease_2 PF13520.6 EPS34359.1 - 5.8e-57 193.4 36.6 7.9e-57 193.0 36.6 1.1 1 0 0 1 1 1 1 Amino acid permease Bestrophin PF01062.21 EPS34363.1 - 6.2e-37 127.6 0.0 1.1e-36 126.8 0.0 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel T6SS_VasE PF05936.12 EPS34363.1 - 0.079 11.6 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE Sugar_tr PF00083.24 EPS34365.1 - 2.2e-79 267.4 20.7 2.6e-79 267.2 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS34365.1 - 3e-12 46.1 40.5 3e-08 33.0 29.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Orthoreo_P17 PF07272.11 EPS34366.1 - 0.0087 16.1 0.0 0.012 15.6 0.0 1.2 1 0 0 1 1 1 1 Orthoreovirus P17 protein GSH_synth_ATP PF03917.17 EPS34367.1 - 8.6e-134 446.0 0.0 9.7e-134 445.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 EPS34367.1 - 1.9e-28 98.9 0.0 3.3e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase SNF2_N PF00176.23 EPS34368.1 - 5.7e-45 153.6 0.0 1.1e-44 152.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EPS34368.1 - 7.3e-18 64.9 0.0 2.2e-17 63.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPS34368.1 - 1e-06 28.9 0.0 2.4e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 EPS34368.1 - 5.1e-06 26.3 0.0 0.00087 19.0 0.0 2.5 2 0 0 2 2 2 1 SWI2/SNF2 ATPase SAM_2 PF07647.17 EPS34368.1 - 4.6e-05 23.4 0.0 0.00023 21.2 0.0 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) DEAD PF00270.29 EPS34368.1 - 0.003 17.4 0.0 0.01 15.6 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase SAM_1 PF00536.30 EPS34368.1 - 0.0044 17.4 0.1 0.019 15.4 0.1 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) ERCC3_RAD25_C PF16203.5 EPS34368.1 - 0.02 14.1 0.0 0.038 13.2 0.0 1.4 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase DUF913 PF06025.12 EPS34368.1 - 0.45 9.5 0.0 0.45 9.5 0.0 2.5 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) BNR_2 PF13088.6 EPS34369.1 - 1.4e-05 24.6 0.0 0.031 13.6 0.0 3.4 1 1 1 3 3 3 2 BNR repeat-like domain BNR PF02012.20 EPS34369.1 - 0.0032 17.2 4.0 0.5 10.6 0.1 3.4 3 0 0 3 3 3 2 BNR/Asp-box repeat BNR_6 PF15899.5 EPS34369.1 - 0.0034 17.3 0.9 0.062 13.4 0.1 2.7 2 0 0 2 2 2 1 BNR-Asp box repeat Sortilin-Vps10 PF15902.5 EPS34369.1 - 0.0069 15.2 0.3 2.2 7.0 0.0 2.5 2 1 0 3 3 3 2 Sortilin, neurotensin receptor 3, F5_F8_type_C PF00754.25 EPS34369.1 - 0.077 13.1 0.0 27 4.9 0.0 3.4 4 0 0 4 4 4 0 F5/8 type C domain SNF2_N PF00176.23 EPS34370.1 - 2.6e-63 213.9 0.0 5.3e-63 212.9 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 EPS34370.1 - 2.5e-20 72.2 0.0 5.2e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.31 EPS34370.1 - 2.1e-14 53.8 0.0 4.7e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 EPS34370.1 - 9.1e-12 44.6 9.2 2.3e-11 43.3 9.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EPS34370.1 - 1.2e-10 41.1 8.3 1.2e-10 41.1 8.3 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EPS34370.1 - 2.8e-09 36.7 10.4 2.8e-09 36.7 10.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EPS34370.1 - 8.5e-09 35.6 9.1 8.5e-09 35.6 9.1 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.6 EPS34370.1 - 1.4e-07 31.5 8.6 2.9e-07 30.5 8.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EPS34370.1 - 1.5e-07 31.3 5.7 4.3e-07 29.9 5.7 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EPS34370.1 - 3.8e-07 30.0 8.7 9.1e-07 28.7 8.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EPS34370.1 - 1.2e-06 28.2 7.5 1.2e-06 28.2 7.5 1.8 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EPS34370.1 - 7.5e-06 26.1 6.5 2e-05 24.8 6.5 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 EPS34370.1 - 0.00048 19.9 5.5 0.0022 17.7 5.7 2.0 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 EPS34370.1 - 0.0093 16.1 4.9 0.024 14.8 4.9 1.7 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_6 PF14835.6 EPS34370.1 - 0.015 15.1 3.3 0.032 14.1 3.3 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 EPS34370.1 - 0.043 13.6 7.0 0.092 12.6 7.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DELLA PF12041.8 EPS34370.1 - 0.057 13.3 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Transcriptional regulator DELLA protein N terminal zf-RING_11 PF17123.5 EPS34370.1 - 0.087 12.6 4.1 0.31 10.8 4.1 2.1 1 0 0 1 1 1 0 RING-like zinc finger zf-ANAPC11 PF12861.7 EPS34370.1 - 0.23 11.5 2.0 0.66 10.1 2.0 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1272 PF06906.11 EPS34370.1 - 0.56 10.3 4.9 1.3 9.2 4.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) MBOAT_2 PF13813.6 EPS34371.1 - 3.3e-19 68.9 5.6 3.3e-19 68.9 5.6 2.3 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family RIX1 PF08167.12 EPS34372.1 - 4.3e-63 212.5 1.7 1.4e-62 210.8 1.0 2.1 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis DUF4805 PF16063.5 EPS34372.1 - 0.12 11.7 1.9 0.23 10.8 1.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) TPR_14 PF13428.6 EPS34373.1 - 1.4e-13 50.4 13.3 0.011 16.5 0.0 8.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 EPS34373.1 - 2.3e-06 27.4 2.3 18 5.9 0.0 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.17 EPS34373.1 - 2.3e-06 27.3 7.6 1.9 8.8 0.0 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_1 PF00515.28 EPS34373.1 - 1.9e-05 24.3 0.5 4.2 7.4 0.0 5.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 EPS34373.1 - 8.7e-05 22.7 5.4 2.8 8.3 0.3 5.8 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 EPS34373.1 - 0.00094 19.8 8.2 1.5 9.6 0.0 6.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 EPS34373.1 - 0.0026 18.2 8.5 1.6 9.3 0.0 5.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 EPS34373.1 - 0.012 16.0 4.1 23 5.7 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 EPS34373.1 - 0.099 12.8 1.0 1.8 8.8 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat NDUFA12 PF05071.16 EPS34374.1 - 2.1e-29 102.2 3.0 2.6e-29 101.9 3.0 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 INTAP PF16617.5 EPS34374.1 - 0.16 12.3 3.3 0.11 12.9 1.1 1.7 1 1 1 2 2 2 0 Intersectin and clathrin adaptor AP2 binding region PLDc_2 PF13091.6 EPS34375.1 - 2.9e-16 59.6 0.0 1.4e-08 34.7 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EPS34375.1 - 4.8e-10 39.2 0.9 0.00047 20.2 0.1 3.1 2 1 0 2 2 2 2 Phospholipase D Active site motif LTV PF04180.14 EPS34376.1 - 4.9e-124 414.9 13.6 5.6e-124 414.8 13.6 1.0 1 0 0 1 1 1 1 Low temperature viability protein MMR_HSR1 PF01926.23 EPS34377.1 - 4.3e-16 59.0 2.9 4e-14 52.7 0.0 2.8 3 0 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EPS34377.1 - 7.5e-07 28.8 0.3 2.3e-05 23.9 0.1 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EPS34377.1 - 4.4e-05 23.5 0.2 0.016 15.1 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 EPS34377.1 - 0.0046 16.3 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 EPS34377.1 - 0.0078 16.3 5.8 0.25 11.4 0.3 3.5 3 1 0 3 3 3 2 Dynamin family cobW PF02492.19 EPS34377.1 - 0.1 12.2 0.3 0.56 9.8 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EPS34377.1 - 0.12 11.3 0.4 0.29 10.1 0.0 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Acyl-CoA_dh_1 PF00441.24 EPS34378.1 - 8.7e-29 100.7 3.2 1.5e-28 99.9 3.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EPS34378.1 - 9.1e-21 73.9 0.0 1.8e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EPS34378.1 - 4.9e-15 56.2 0.5 9.3e-15 55.3 0.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EPS34378.1 - 4.2e-12 46.5 3.6 7.2e-12 45.7 3.6 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Sec8_exocyst PF04048.14 EPS34378.1 - 0.042 13.7 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain CinA_KH PF18146.1 EPS34378.1 - 0.16 12.2 0.9 0.96 9.6 0.2 2.6 3 0 0 3 3 3 0 Damage-inducible protein CinA KH domain HemY_N PF07219.13 EPS34378.1 - 0.53 10.5 3.0 4.5 7.5 0.3 2.6 3 0 0 3 3 3 0 HemY protein N-terminus Spo12 PF05032.12 EPS34379.1 - 1.2e-16 60.3 2.4 2e-16 59.6 2.4 1.4 1 0 0 1 1 1 1 Spo12 family Sad1_UNC PF07738.13 EPS34380.1 - 4.5e-31 107.6 0.0 8.4e-31 106.7 0.0 1.5 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal CEP63 PF17045.5 EPS34380.1 - 0.081 12.8 5.3 0.14 12.1 5.3 1.2 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa Col_cuticle_N PF01484.17 EPS34380.1 - 1.4 9.1 3.1 0.9 9.7 0.1 2.2 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain Pkinase PF00069.25 EPS34381.1 - 1.3e-54 185.4 0.0 1.8e-54 184.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS34381.1 - 1.1e-35 123.2 0.0 1.5e-35 122.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EPS34381.1 - 6.8e-09 35.4 0.0 3.3e-06 26.7 0.0 2.5 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.14 EPS34381.1 - 0.021 14.2 0.1 0.036 13.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HSP9_HSP12 PF04119.12 EPS34384.1 - 0.054 13.9 1.4 2.9 8.4 0.5 2.1 2 0 0 2 2 2 0 Heat shock protein 9/12 Pep3_Vps18 PF05131.14 EPS34385.1 - 2.7e-45 153.9 0.0 2.1e-44 150.9 0.0 2.4 3 0 0 3 3 3 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 EPS34385.1 - 3e-09 36.9 8.0 2.7e-05 24.1 0.3 3.9 2 1 2 4 4 4 2 Region in Clathrin and VPS Zn_ribbon_17 PF17120.5 EPS34385.1 - 0.00033 20.2 0.1 0.00068 19.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 EPS34385.1 - 0.00044 20.2 0.3 0.00099 19.0 0.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EPS34385.1 - 0.0026 17.6 0.7 0.0026 17.6 0.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Vps39_2 PF10367.9 EPS34385.1 - 0.0029 18.0 0.0 0.0081 16.6 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_11 PF17123.5 EPS34385.1 - 0.0034 17.1 4.2 0.0034 17.1 4.2 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_2 PF13639.6 EPS34385.1 - 0.0047 17.2 1.1 0.012 15.9 1.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EPS34385.1 - 0.03 14.4 0.5 0.07 13.2 0.5 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 EPS34385.1 - 0.072 13.4 0.3 0.33 11.3 0.5 1.9 2 0 0 2 2 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EPS34385.1 - 0.08 12.8 0.2 0.22 11.4 0.2 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2175 PF09943.9 EPS34385.1 - 0.1 12.9 0.0 0.46 10.8 0.0 2.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) zf-C3H2C3 PF17122.5 EPS34385.1 - 0.68 10.0 5.1 0.1 12.6 1.0 1.8 2 0 0 2 2 2 0 Zinc-finger UCH PF00443.29 EPS34386.1 - 8.6e-16 58.2 0.0 2.3e-15 56.8 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EPS34386.1 - 7.7e-14 52.0 0.0 1.3e-06 28.3 0.0 2.6 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase EnY2 PF10163.9 EPS34386.1 - 0.084 13.3 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Transcription factor e(y)2 Ribosomal_L5_C PF00673.21 EPS34387.1 - 1.6e-29 101.9 0.0 2.7e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EPS34387.1 - 2.5e-06 27.7 0.0 5.1e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 Pkinase PF00069.25 EPS34388.1 - 4.2e-68 229.6 0.0 7.2e-68 228.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS34388.1 - 1.2e-48 165.6 0.0 4.1e-48 163.9 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 EPS34388.1 - 4.3e-26 91.2 0.0 8e-26 90.3 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.30 EPS34388.1 - 1.3e-14 54.4 0.8 2.2e-14 53.6 0.1 1.8 2 0 0 2 2 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EPS34388.1 - 6.3e-12 45.4 0.1 1.4e-11 44.3 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.6 EPS34388.1 - 8e-09 35.2 0.0 4.5e-05 22.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like RA PF00788.23 EPS34388.1 - 0.001 19.7 0.0 0.0018 18.9 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Pkinase_fungal PF17667.1 EPS34388.1 - 0.0022 16.9 0.6 0.0038 16.1 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase CUE PF02845.16 EPS34388.1 - 0.046 13.4 0.2 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 CUE domain Kdo PF06293.14 EPS34388.1 - 0.05 13.0 0.0 0.098 12.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EPS34388.1 - 0.081 12.0 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 SAM_4 PF18017.1 EPS34388.1 - 0.14 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) MSA-2c PF12238.8 EPS34388.1 - 0.81 9.7 0.0 0.81 9.7 0.0 2.8 3 0 0 3 3 1 0 Merozoite surface antigen 2c Transferase PF02458.15 EPS34389.1 - 6.2e-27 94.3 0.0 5.5e-14 51.7 0.0 3.2 3 0 0 3 3 3 3 Transferase family Glyco_transf_90 PF05686.12 EPS34390.1 - 5.1e-20 71.8 2.3 1.6e-17 63.5 1.9 3.3 2 1 0 2 2 2 2 Glycosyl transferase family 90 Fungal_trans PF04082.18 EPS34391.1 - 3.2e-13 49.3 0.7 3.2e-13 49.3 0.7 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EPS34391.1 - 6.7e-12 45.2 8.2 2.5e-05 24.5 2.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPS34391.1 - 9.3e-09 35.4 8.3 0.00087 19.9 2.3 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EPS34391.1 - 5.7e-08 32.8 2.4 5.7e-08 32.8 2.4 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.8 EPS34391.1 - 2.1e-05 24.6 1.1 0.23 11.8 0.5 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.6 EPS34391.1 - 0.0005 19.9 2.2 0.35 10.8 0.2 2.8 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.6 EPS34391.1 - 0.0062 16.5 7.6 0.95 9.5 2.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HE PF16278.5 EPS34391.1 - 0.015 15.7 3.0 0.015 15.7 3.0 2.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 EPS34391.1 - 0.12 12.8 3.2 8.8 6.9 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type BolA PF01722.18 EPS34391.1 - 0.25 11.6 2.0 0.84 10.0 0.5 2.6 2 1 0 2 2 2 0 BolA-like protein zf-H2C2_5 PF13909.6 EPS34391.1 - 3.4 7.5 7.2 0.62 9.9 2.4 2.4 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 EPS34392.1 - 0.087 13.3 2.0 0.087 13.3 2.0 3.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type DUF629 PF04780.12 EPS34392.1 - 2.2 6.7 7.5 1.2 7.6 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_4 PF13894.6 EPS34392.1 - 4.5 8.4 13.4 0.58 11.1 1.2 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger EST1_DNA_bind PF10373.9 EPS34393.1 - 2e-69 234.2 0.3 1.9e-68 231.0 0.0 2.1 2 0 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.9 EPS34393.1 - 2.6e-22 79.9 1.0 1e-21 78.0 0.7 2.1 2 0 0 2 2 2 1 Telomerase activating protein Est1 PfkB PF00294.24 EPS34394.1 - 2.7e-68 230.5 0.1 3.1e-68 230.3 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DUF1770 PF08589.10 EPS34395.1 - 1.5e-32 112.4 0.6 2e-32 112.1 0.6 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) WHIM1 PF15612.6 EPS34396.1 - 4.3e-08 32.5 0.0 9.3e-08 31.4 0.0 1.5 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Ribosomal_L2_C PF03947.18 EPS34397.1 - 2.7e-42 143.9 5.5 4.6e-42 143.2 5.5 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EPS34397.1 - 4.2e-13 49.1 0.9 7.4e-13 48.3 0.2 1.8 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain BAR PF03114.18 EPS34398.1 - 6.1e-50 170.1 3.8 8.9e-50 169.6 3.8 1.2 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.9 EPS34398.1 - 5.9e-07 28.9 1.6 8e-07 28.5 1.6 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking APG6_N PF17675.1 EPS34398.1 - 0.21 12.1 9.0 0.025 15.1 3.3 2.1 2 1 0 2 2 2 0 Apg6 coiled-coil region SNF2_N PF00176.23 EPS34399.1 - 1.1e-73 248.0 0.9 2.5e-73 246.8 0.9 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Bromodomain PF00439.25 EPS34399.1 - 1e-21 76.8 0.2 3.1e-21 75.2 0.2 1.8 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.31 EPS34399.1 - 2.4e-19 69.7 5.3 5.3e-19 68.6 0.0 3.6 4 1 1 5 5 5 1 Helicase conserved C-terminal domain HSA PF07529.13 EPS34399.1 - 9.8e-18 64.3 13.2 9.8e-18 64.3 13.2 3.9 5 0 0 5 5 5 1 HSA QLQ PF08880.11 EPS34399.1 - 1.2e-12 47.3 2.3 3.2e-12 46.0 2.3 1.8 1 0 0 1 1 1 1 QLQ ResIII PF04851.15 EPS34399.1 - 1.5e-09 38.1 0.0 1.5e-09 38.1 0.0 3.1 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit SnAC PF14619.6 EPS34399.1 - 4e-09 36.9 1.6 4e-09 36.9 1.6 3.6 4 1 1 5 5 5 1 Snf2-ATP coupling, chromatin remodelling complex T2SSF PF00482.23 EPS34399.1 - 1.8 8.5 7.8 8 6.4 0.0 3.6 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F Abhydro_lipase PF04083.16 EPS34400.1 - 1.1e-21 76.2 0.1 2.3e-21 75.1 0.1 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 EPS34400.1 - 1e-20 74.5 0.0 1.9e-20 73.6 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EPS34400.1 - 0.00052 19.3 0.0 0.042 13.1 0.0 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 FSH1 PF03959.13 EPS34400.1 - 0.014 15.1 0.0 4.4 6.9 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase (FSH1) TRIC PF05197.13 EPS34400.1 - 0.48 10.0 3.4 0.14 11.7 0.4 1.6 2 0 0 2 2 2 0 TRIC channel Pet191_N PF10203.9 EPS34401.1 - 1.6e-29 102.0 5.8 2.1e-29 101.6 5.8 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 EPS34401.1 - 0.025 14.6 4.1 2.3 8.3 0.3 2.5 2 1 0 2 2 2 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 EPS34401.1 - 0.043 13.8 3.5 2.3 8.3 0.3 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like PAN_3 PF08277.12 EPS34401.1 - 0.14 12.0 0.3 0.27 11.1 0.3 1.4 1 0 0 1 1 1 0 PAN-like domain DDOST_48kD PF03345.14 EPS34402.1 - 5.1e-159 529.6 0.0 6e-159 529.3 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF1116 PF06545.11 EPS34402.1 - 0.065 12.7 0.0 0.41 10.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1116) IMS PF00817.20 EPS34406.1 - 6e-37 126.9 0.0 1.6e-34 119.1 0.0 2.5 1 1 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 EPS34406.1 - 9.4e-15 55.3 0.0 2.8e-14 53.8 0.0 1.8 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain zf_UBZ PF18439.1 EPS34406.1 - 9.4e-13 47.5 3.2 2e-12 46.5 3.2 1.6 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger WSC PF01822.19 EPS34409.1 - 1e-07 32.0 12.6 1e-07 32.0 12.6 2.4 2 0 0 2 2 2 1 WSC domain Amnionless PF14828.6 EPS34409.1 - 0.021 13.7 0.1 0.035 13.0 0.1 1.4 1 1 0 1 1 1 0 Amnionless Apt1 PF10351.9 EPS34409.1 - 0.034 13.0 1.4 0.038 12.9 1.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain BatA PF07584.11 EPS34409.1 - 0.28 11.6 0.0 0.28 11.6 0.0 1.8 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal SOG2 PF10428.9 EPS34409.1 - 0.59 9.3 13.4 0.9 8.7 13.4 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4614 PF15391.6 EPS34409.1 - 1.9 8.4 14.8 4 7.4 14.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Ank_2 PF12796.7 EPS34410.1 - 4e-36 123.4 0.0 1.7e-09 38.1 0.0 4.3 1 1 5 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPS34410.1 - 2e-24 85.6 0.4 7.6e-06 26.4 0.0 6.0 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EPS34410.1 - 3.5e-22 78.2 3.3 4.2e-09 36.5 0.4 6.4 3 3 3 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPS34410.1 - 7.5e-22 75.1 0.2 0.00026 21.2 0.0 8.1 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.30 EPS34410.1 - 4.7e-16 58.4 0.4 1.1e-06 28.8 0.1 6.4 7 1 0 7 7 7 2 Ankyrin repeat F-box-like PF12937.7 EPS34410.1 - 1.4e-05 24.9 0.2 3.2e-05 23.7 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EPS34410.1 - 1.9e-05 24.4 0.1 4.4e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EPS34410.1 - 0.031 14.1 0.1 0.067 13.1 0.1 1.5 1 0 0 1 1 1 0 F-box Ank_4 PF13637.6 EPS34411.1 - 2.5e-25 88.5 2.3 6.8e-09 36.1 0.0 4.8 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 EPS34411.1 - 1.9e-22 79.7 0.8 6.3e-07 29.9 0.0 4.0 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EPS34411.1 - 1.2e-17 63.7 3.0 0.0016 18.7 0.1 5.8 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPS34411.1 - 1.2e-17 62.2 7.5 0.59 10.9 0.1 8.5 9 0 0 9 9 9 5 Ankyrin repeat Ank PF00023.30 EPS34411.1 - 5e-11 42.5 13.6 1.4 9.5 0.0 7.1 7 0 0 7 7 7 6 Ankyrin repeat F-box PF00646.33 EPS34411.1 - 0.00028 20.7 0.0 0.00066 19.5 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EPS34411.1 - 0.00042 20.1 0.1 0.00089 19.1 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 EPS34411.1 - 0.013 15.4 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 F-box Sugar_tr PF00083.24 EPS34413.1 - 4.1e-122 408.3 16.8 6.2e-122 407.7 16.8 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS34413.1 - 2.4e-30 105.7 52.1 3e-24 85.6 30.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily OTT_1508_deam PF14441.6 EPS34414.1 - 2.5e-19 69.0 1.3 5.5e-19 67.9 1.3 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase Endotoxin_N PF03945.14 EPS34414.1 - 0.038 13.7 0.4 0.21 11.3 0.2 2.2 2 0 0 2 2 2 0 delta endotoxin, N-terminal domain DYW_deaminase PF14432.6 EPS34414.1 - 0.042 13.7 0.6 0.14 12.0 0.6 1.9 1 0 0 1 1 1 0 DYW family of nucleic acid deaminases DUF3445 PF11927.8 EPS34415.1 - 3.9e-77 258.9 0.0 5.5e-77 258.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) adh_short PF00106.25 EPS34416.1 - 1.4e-44 151.9 0.4 1.8e-44 151.5 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS34416.1 - 3.6e-29 102.0 1.2 4.7e-29 101.6 1.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EPS34416.1 - 1.6e-06 27.8 0.4 4.1e-06 26.4 0.4 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EPS34416.1 - 0.00022 20.7 0.0 0.00032 20.2 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 EPS34416.1 - 0.00064 18.9 0.0 0.00093 18.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 EPS34416.1 - 0.0023 17.9 0.3 0.0034 17.3 0.3 1.3 1 0 0 1 1 1 1 KR domain PRP38 PF03371.15 EPS34417.1 - 2e-62 210.2 0.0 2.5e-62 209.8 0.0 1.0 1 0 0 1 1 1 1 PRP38 family Tnp_22_trimer PF17489.2 EPS34417.1 - 0.057 13.4 1.2 0.12 12.4 1.2 1.4 1 0 0 1 1 1 0 L1 transposable element trimerization domain WD40 PF00400.32 EPS34419.1 - 4.4e-18 65.3 0.3 0.041 14.8 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS34419.1 - 0.00042 20.6 0.0 20 5.6 0.0 4.2 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain AAA_12 PF13087.6 EPS34420.1 - 3.1e-23 82.5 0.1 3.8e-15 56.0 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_11 PF13086.6 EPS34420.1 - 1.2e-11 44.9 0.2 6.9e-11 42.4 0.2 2.1 1 1 0 1 1 1 1 AAA domain Fungal_trans PF04082.18 EPS34421.1 - 0.0028 16.7 0.0 0.019 14.0 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EPS34422.1 - 3.8e-08 33.3 11.3 2.3e-05 24.6 3.9 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EPS34422.1 - 9.9e-05 22.9 8.7 0.0021 18.7 2.5 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EPS34422.1 - 0.0041 17.5 1.5 0.0041 17.5 1.5 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_11 PF16622.5 EPS34422.1 - 0.019 14.7 6.8 0.19 11.5 0.4 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-UBR PF02207.20 EPS34422.1 - 0.043 14.0 0.6 0.073 13.2 0.6 1.2 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) zf-C2HC_2 PF13913.6 EPS34422.1 - 0.13 12.2 2.3 0.26 11.2 2.3 1.5 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-BED PF02892.15 EPS34422.1 - 2 8.5 4.8 1.1 9.3 1.9 1.9 1 1 1 2 2 2 0 BED zinc finger adh_short_C2 PF13561.6 EPS34423.1 - 1.2e-57 195.2 0.3 1.9e-57 194.5 0.3 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPS34423.1 - 1.6e-43 148.5 0.0 2.3e-43 148.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPS34423.1 - 1.5e-06 28.2 0.1 5.5e-06 26.4 0.1 1.9 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EPS34423.1 - 0.0012 18.0 0.0 0.0027 16.9 0.0 1.5 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein ThiF PF00899.21 EPS34423.1 - 0.0032 16.8 1.8 0.02 14.2 0.9 2.1 1 1 1 2 2 2 1 ThiF family DUF5448 PF17526.2 EPS34423.1 - 0.062 13.5 0.0 0.14 12.3 0.0 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5448) Amidase PF01425.21 EPS34424.1 - 2.3e-89 300.5 0.0 2.8e-89 300.1 0.0 1.0 1 0 0 1 1 1 1 Amidase Polysacc_deac_1 PF01522.21 EPS34425.1 - 4.4e-19 68.6 0.0 8.6e-19 67.7 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.9 EPS34425.1 - 3.5e-06 26.8 0.2 1e-05 25.3 0.2 1.7 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) DUF2194 PF09960.9 EPS34425.1 - 0.12 10.8 0.0 0.15 10.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein conserved in bacteria (DUF2194) Aa_trans PF01490.18 EPS34426.1 - 3.8e-27 95.0 31.9 4.7e-27 94.7 31.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 EPS34426.1 - 8.8e-07 28.1 22.7 8.8e-07 28.1 22.7 2.3 1 1 0 2 2 2 1 Amino acid permease ABC_tran PF00005.27 EPS34428.1 - 2.1e-54 183.7 0.0 1.1e-31 110.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 EPS34428.1 - 2.6e-51 174.9 22.7 8.6e-33 114.1 4.5 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.19 EPS34428.1 - 4.7e-07 29.5 1.9 0.093 12.1 0.2 4.2 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EPS34428.1 - 3.8e-06 27.6 0.2 0.0054 17.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EPS34428.1 - 4e-05 23.7 0.1 0.047 13.8 0.1 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EPS34428.1 - 0.00011 22.6 0.7 1.1 9.7 0.3 3.1 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EPS34428.1 - 0.00017 21.6 0.6 0.29 11.0 0.0 2.7 3 0 0 3 3 2 2 RsgA GTPase AAA_21 PF13304.6 EPS34428.1 - 0.00024 21.0 1.3 0.33 10.7 0.0 3.2 2 1 0 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EPS34428.1 - 0.00057 20.2 2.4 1 9.6 0.3 3.4 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EPS34428.1 - 0.00061 19.5 2.0 0.45 10.3 0.1 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain T2SSE PF00437.20 EPS34428.1 - 0.00078 18.6 0.0 0.021 13.9 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.6 EPS34428.1 - 0.0014 18.3 0.1 0.32 10.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 EPS34428.1 - 0.0016 18.5 1.0 0.052 13.6 0.1 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain Zeta_toxin PF06414.12 EPS34428.1 - 0.0051 16.1 1.1 1.3 8.2 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin IstB_IS21 PF01695.17 EPS34428.1 - 0.0085 15.8 0.2 1.1 9.0 0.0 2.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_7 PF12775.7 EPS34428.1 - 0.018 14.5 0.1 2.2 7.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 EPS34428.1 - 0.045 13.7 1.3 0.96 9.4 0.1 2.5 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 EPS34428.1 - 0.047 13.4 1.7 7.4 6.2 0.0 3.5 3 0 0 3 3 3 0 AAA domain TrwB_AAD_bind PF10412.9 EPS34428.1 - 0.079 11.9 2.2 5 5.9 0.2 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.29 EPS34428.1 - 0.085 13.3 1.2 8.8 6.8 0.1 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 EPS34428.1 - 0.096 12.0 0.5 2.1 7.6 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_24 PF13479.6 EPS34428.1 - 0.097 12.4 0.1 3.8 7.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EPS34428.1 - 0.13 11.9 1.6 0.59 9.7 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Sigma54_activat PF00158.26 EPS34428.1 - 0.14 11.8 0.0 0.83 9.3 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.6 EPS34428.1 - 0.16 12.5 1.0 16 6.1 0.1 2.9 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EPS34428.1 - 0.17 11.3 1.7 28 4.1 0.0 3.2 3 0 0 3 3 3 0 PhoH-like protein Dynamin_N PF00350.23 EPS34428.1 - 0.2 11.7 1.0 17 5.4 0.0 3.0 3 0 0 3 3 3 0 Dynamin family Roc PF08477.13 EPS34428.1 - 0.21 11.8 0.3 15 5.9 0.1 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase TIP49 PF06068.13 EPS34428.1 - 5.5 6.1 5.5 22 4.1 0.1 2.6 3 0 0 3 3 3 0 TIP49 P-loop domain UQ_con PF00179.26 EPS34429.1 - 8.1e-31 106.5 0.0 1e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Sugar_tr PF00083.24 EPS34431.1 - 2.2e-82 277.3 21.6 2.6e-82 277.1 21.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS34431.1 - 3.4e-39 134.8 41.7 2.1e-33 115.7 25.4 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EPS34431.1 - 0.001 17.6 1.6 0.001 17.6 1.6 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1201 PF06716.11 EPS34431.1 - 0.14 12.2 2.6 3.6 7.7 0.9 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) Peptidase_S8 PF00082.22 EPS34432.1 - 1.2e-36 126.5 11.3 1.2e-36 126.5 11.3 2.2 2 1 0 3 3 3 1 Subtilase family Inhibitor_I9 PF05922.16 EPS34432.1 - 5.1e-19 68.7 0.8 1.2e-18 67.6 0.8 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Beach PF02138.18 EPS34433.1 - 2.3e-120 401.2 0.1 6.6e-120 399.6 0.0 1.9 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.6 EPS34433.1 - 4.2e-12 46.0 0.0 1e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 EPS34433.1 - 1.7e-10 41.2 0.0 5e-10 39.7 0.0 1.7 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 EPS34433.1 - 2.9e-06 27.9 2.3 0.015 16.2 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat TMEM192 PF14802.6 EPS34433.1 - 0.14 11.2 0.2 0.29 10.2 0.2 1.5 1 0 0 1 1 1 0 TMEM192 family TAL_FSA PF00923.19 EPS34434.1 - 1.7e-96 323.0 0.3 1.9e-96 322.8 0.3 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase C5-epim_C PF06662.13 EPS34434.1 - 0.086 12.3 0.0 0.19 11.2 0.0 1.5 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus Sod_Cu PF00080.20 EPS34435.1 - 9.7e-47 158.7 4.6 1.1e-46 158.5 4.6 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) SNase PF00565.17 EPS34436.1 - 7.6e-76 251.6 0.0 8.1e-25 87.4 0.0 5.6 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 EPS34436.1 - 7.5e-24 84.1 0.0 2e-23 82.8 0.0 1.8 1 0 0 1 1 1 1 Tudor domain SMN PF06003.12 EPS34436.1 - 0.0002 20.7 0.1 0.00048 19.5 0.0 1.6 2 0 0 2 2 2 1 Survival motor neuron protein (SMN) Agenet PF05641.12 EPS34436.1 - 0.069 13.6 0.0 0.35 11.4 0.1 2.3 2 0 0 2 2 2 0 Agenet domain CRAL_TRIO PF00650.20 EPS34437.1 - 6.8e-26 90.9 0.0 9.1e-26 90.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EPS34437.1 - 8.4e-10 38.7 0.0 2.4e-09 37.2 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DUF1455 PF07306.11 EPS34437.1 - 0.17 11.9 0.2 2.4 8.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1455) FA_hydroxylase PF04116.13 EPS34438.1 - 8e-22 78.0 12.7 8e-22 78.0 12.7 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Dynamin_N PF00350.23 EPS34439.1 - 6.6e-15 55.6 0.1 1.3e-12 48.2 0.0 3.2 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 EPS34439.1 - 2.3e-06 27.7 0.0 0.0021 18.2 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase ABC_tran PF00005.27 EPS34439.1 - 4.3e-05 24.0 0.1 0.00014 22.3 0.0 2.1 2 0 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 EPS34439.1 - 7.7e-05 22.7 0.1 0.00035 20.5 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_18 PF13238.6 EPS34439.1 - 0.00037 21.1 0.0 0.0057 17.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AIG1 PF04548.16 EPS34439.1 - 0.0013 18.1 0.0 0.0071 15.7 0.0 2.1 2 0 0 2 2 2 1 AIG1 family AAA_16 PF13191.6 EPS34439.1 - 0.0015 18.9 0.0 0.0073 16.7 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EPS34439.1 - 0.13 12.1 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Herpes_glycoH_C PF17488.2 EPS34439.1 - 0.18 11.6 0.0 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus glycoprotein H C-terminal domain DUF87 PF01935.17 EPS34439.1 - 0.44 10.6 12.0 4.4 7.3 0.3 3.9 3 1 0 3 3 3 0 Helicase HerA, central domain Glycos_transf_3 PF00591.21 EPS34440.1 - 1.6e-54 185.2 0.0 2.6e-53 181.2 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 EPS34440.1 - 1.7e-08 34.1 0.3 4.9e-08 32.7 0.1 1.8 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain EMC1_C PF07774.13 EPS34441.1 - 1.2e-75 253.8 0.0 3.1e-75 252.5 0.0 1.7 2 0 0 2 2 2 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 EPS34441.1 - 5.4e-26 91.6 17.2 3.7e-25 88.9 2.9 3.6 3 1 1 4 4 4 2 PQQ-like domain PQQ PF01011.21 EPS34441.1 - 0.00088 19.1 0.2 4.1 7.5 0.0 5.5 6 0 0 6 6 6 1 PQQ enzyme repeat Ribonuc_L-PSP PF01042.21 EPS34442.1 - 4.6e-11 42.8 0.0 5.9e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Chitin_synth_1 PF01644.17 EPS34443.1 - 1.1e-69 233.6 0.0 2.1e-69 232.7 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 EPS34443.1 - 3.3e-27 94.3 0.0 1.6e-26 92.1 0.0 2.0 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 EPS34443.1 - 1.1e-23 83.7 1.0 4.4e-19 68.5 0.0 2.1 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EPS34443.1 - 6.2e-07 29.5 6.8 6.2e-07 29.5 6.8 2.8 2 1 0 2 2 2 1 Glycosyl transferase family group 2 DUF1479 PF07350.12 EPS34444.1 - 6.5e-167 555.5 0.0 7.7e-167 555.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.13 EPS34444.1 - 0.13 12.5 0.1 2.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) HupF_HypC PF01455.18 EPS34444.1 - 0.18 12.0 0.0 0.36 11.0 0.0 1.4 1 0 0 1 1 1 0 HupF/HypC family Pkinase PF00069.25 EPS34445.1 - 9.7e-13 48.1 0.0 1.5e-12 47.5 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS34445.1 - 1.2e-09 37.8 0.0 1.5e-08 34.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EPS34445.1 - 0.0017 17.7 0.0 0.018 14.4 0.0 2.0 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EPS34445.1 - 0.059 12.7 0.0 0.09 12.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EPS34445.1 - 0.091 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 EPS34445.1 - 0.23 11.0 0.0 0.38 10.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Glu_cys_ligase PF04262.14 EPS34446.1 - 0.086 11.4 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Glutamate-cysteine ligase Aa_trans PF01490.18 EPS34448.1 - 1.1e-97 327.4 13.5 1.6e-97 326.8 13.5 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EPS34448.1 - 3.3e-05 23.1 16.1 3.3e-05 23.1 16.1 1.9 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family DUF3149 PF11346.8 EPS34448.1 - 2.7 7.7 6.0 10 5.8 2.3 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) Bax1-I PF01027.20 EPS34449.1 - 1.5e-50 172.0 31.9 1.7e-50 171.8 31.9 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Peroxidase_2 PF01328.17 EPS34450.1 - 6.1e-50 170.4 0.2 7.4e-50 170.1 0.2 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 EXS PF03124.14 EPS34451.1 - 1.2e-96 323.9 34.0 1.6e-96 323.6 34.0 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.19 EPS34451.1 - 1.7e-74 252.1 0.9 1.7e-74 252.1 0.9 2.2 2 0 0 2 2 2 1 SPX domain Glyco_hydro_15 PF00723.21 EPS34453.1 - 1.8e-103 346.7 0.2 2.4e-103 346.4 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.19 EPS34453.1 - 9.3e-37 124.8 0.4 3e-36 123.2 0.4 1.9 1 0 0 1 1 1 1 Starch binding domain Abhydrolase_2 PF02230.16 EPS34454.1 - 2e-17 63.8 0.0 2.5e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 EPS34454.1 - 0.008 16.8 0.2 0.0097 16.5 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 EPS34454.1 - 0.16 11.6 0.0 0.46 10.1 0.0 1.7 1 1 0 1 1 1 0 Serine hydrolase (FSH1) RAP PF08373.10 EPS34454.1 - 0.17 12.0 0.0 0.27 11.4 0.0 1.2 1 0 0 1 1 1 0 RAP domain MAPEG PF01124.18 EPS34455.1 - 2.9e-21 75.7 0.1 3.2e-21 75.6 0.1 1.0 1 0 0 1 1 1 1 MAPEG family T4SS_CagC PF16943.5 EPS34455.1 - 0.14 12.4 0.1 0.32 11.2 0.0 1.6 2 0 0 2 2 2 0 Cag pathogenicity island, type IV secretory system Fungal_trans PF04082.18 EPS34456.1 - 1.8e-07 30.5 0.6 2.9e-07 29.8 0.6 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 EPS34459.1 - 1.7e-07 31.3 14.5 0.001 19.4 0.3 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type Fungal_trans PF04082.18 EPS34459.1 - 1.9e-06 27.1 0.0 3.1e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS34459.1 - 1.2e-05 25.3 7.9 1.2e-05 25.3 7.9 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.6 EPS34459.1 - 0.0003 21.4 18.8 0.021 15.6 0.2 4.3 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 EPS34459.1 - 0.17 12.0 5.3 0.3 11.2 5.3 1.4 1 0 0 1 1 1 0 Aberrant zinc-finger PyrI_C PF02748.15 EPS34459.1 - 0.6 10.0 4.1 0.86 9.6 1.9 2.4 2 1 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-H2C2_2 PF13465.6 EPS34459.1 - 0.73 10.4 17.2 0.082 13.4 1.5 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-Di19 PF05605.12 EPS34459.1 - 2.5 8.5 8.8 0.26 11.6 3.8 1.9 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding VWA_N2 PF16164.5 EPS34459.1 - 2.5 8.3 7.1 0.59 10.3 2.7 2.0 2 0 0 2 2 2 0 VWA N-terminal MFS_1 PF07690.16 EPS34460.1 - 2.1e-39 135.5 58.5 1.1e-38 133.2 36.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EPS34460.1 - 4.7e-05 22.0 4.9 4.7e-05 22.0 4.9 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF5536 PF17688.1 EPS34460.1 - 0.0022 17.9 0.1 0.0056 16.6 0.1 1.7 2 1 0 2 2 2 1 Family of unknown function (DUF5536) Lactamase_B_2 PF12706.7 EPS34461.1 - 3.4e-13 49.6 0.0 7e-13 48.6 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EPS34461.1 - 2.9e-08 33.8 0.0 4.3e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EPS34461.1 - 0.05 13.6 0.1 13 5.7 0.0 2.2 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily LRR_4 PF12799.7 EPS34462.1 - 0.23 12.0 2.2 15 6.1 0.5 2.8 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) TPR_2 PF07719.17 EPS34463.1 - 9.6e-12 44.1 4.5 0.00015 21.6 0.0 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 EPS34463.1 - 1.2e-07 31.3 2.2 0.0047 16.7 0.0 5.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 EPS34463.1 - 7.2e-05 22.5 5.7 0.97 9.6 0.0 5.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 EPS34463.1 - 0.00017 21.5 0.4 0.68 10.3 0.0 5.2 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_4 PF07721.14 EPS34463.1 - 0.00041 20.7 1.4 0.65 10.8 0.1 4.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EPS34463.1 - 0.0016 19.1 7.9 28 5.9 0.1 7.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_12 PF13424.6 EPS34463.1 - 0.0049 17.1 10.4 16 5.9 0.1 6.4 6 3 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 EPS34463.1 - 0.0069 16.5 0.2 0.083 13.1 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EPS34463.1 - 0.034 14.8 21.4 3.9 8.2 0.3 7.8 8 2 2 10 10 9 0 Tetratricopeptide repeat TPR_10 PF13374.6 EPS34463.1 - 0.036 13.9 4.0 4.2 7.4 0.0 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 EPS34463.1 - 0.059 13.1 1.1 45 3.8 0.0 4.9 6 0 0 6 6 6 0 TPR repeat Sel1 PF08238.12 EPS34463.1 - 1.6 9.5 4.6 13 6.7 0.1 3.8 3 1 0 3 3 3 0 Sel1 repeat TPR_10 PF13374.6 EPS34465.1 - 8.2e-30 101.8 0.2 6.7e-12 44.9 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 EPS34465.1 - 4.4e-26 91.0 4.6 1.1e-12 48.1 0.5 3.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 EPS34465.1 - 1.8e-08 33.8 0.3 0.038 14.0 0.0 4.2 4 0 0 4 4 3 2 Tetratricopeptide repeat NB-ARC PF00931.22 EPS34465.1 - 1.9e-05 24.0 0.1 0.069 12.3 0.1 2.3 2 0 0 2 2 2 2 NB-ARC domain TPR_2 PF07719.17 EPS34465.1 - 0.00017 21.5 0.1 0.66 10.2 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EPS34465.1 - 0.00018 21.6 2.2 0.31 11.5 0.1 3.9 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_4 PF07721.14 EPS34465.1 - 0.001 19.5 3.4 0.65 10.8 0.5 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EPS34465.1 - 0.0029 17.4 0.0 22 5.1 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 EPS34465.1 - 0.0038 17.7 0.4 0.11 13.1 0.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat AAA_25 PF13481.6 EPS34465.1 - 0.0052 16.4 0.0 0.013 15.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain TPR_MalT PF17874.1 EPS34465.1 - 0.0063 15.9 1.0 0.0063 15.9 1.0 1.7 2 0 0 2 2 2 1 MalT-like TPR region AAA_16 PF13191.6 EPS34465.1 - 0.018 15.5 1.6 0.1 13.0 0.9 2.5 2 1 0 2 2 2 0 AAA ATPase domain Ses_B PF17046.5 EPS34465.1 - 0.032 14.2 1.8 0.055 13.4 1.8 1.4 1 0 0 1 1 1 0 SesB domain on fungal death-pathway protein TPR_14 PF13428.6 EPS34465.1 - 0.04 14.7 1.7 14 6.8 0.1 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EPS34465.1 - 0.083 13.6 0.3 6.5 7.6 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR PF01535.20 EPS34465.1 - 0.12 12.6 0.1 33 5.0 0.1 2.9 2 0 0 2 2 2 0 PPR repeat Helo_like_N PF17111.5 EPS34466.1 - 7.2e-21 74.5 6.5 1.1e-20 73.9 6.5 1.3 1 0 0 1 1 1 1 Fungal N-terminal domain of STAND proteins PRELI PF04707.14 EPS34466.1 - 0.024 14.4 0.5 0.052 13.4 0.0 1.8 2 0 0 2 2 2 0 PRELI-like family SesA PF17107.5 EPS34466.1 - 0.28 11.4 6.9 0.088 13.0 1.2 2.8 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases DUF501 PF04417.12 EPS34466.1 - 0.96 9.3 5.1 0.53 10.1 0.2 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF501) Methyltransf_32 PF13679.6 EPS34467.1 - 3.2e-22 79.2 0.4 1.9e-21 76.7 0.4 2.1 1 1 0 1 1 1 1 Methyltransferase domain Syntaxin-6_N PF09177.11 EPS34468.1 - 1.6e-26 92.8 1.6 3e-26 91.9 0.4 1.9 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 EPS34468.1 - 0.00012 21.9 0.4 0.00012 21.9 0.4 2.0 2 0 0 2 2 2 1 SNARE domain NPV_P10 PF05531.12 EPS34468.1 - 0.00086 19.7 3.8 1.3 9.5 0.0 3.5 4 0 0 4 4 3 1 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.12 EPS34468.1 - 0.014 15.4 1.9 0.62 10.1 0.3 2.3 2 0 0 2 2 2 0 Laminin Domain II DUF4795 PF16043.5 EPS34468.1 - 0.017 14.7 3.8 0.14 11.7 0.5 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4795) Use1 PF09753.9 EPS34468.1 - 0.022 14.5 0.1 0.041 13.6 0.1 1.4 1 1 0 1 1 1 0 Membrane fusion protein Use1 Prominin PF05478.11 EPS34468.1 - 0.023 12.7 0.1 0.11 10.4 0.1 1.8 1 1 0 1 1 1 0 Prominin STAT_alpha PF01017.20 EPS34468.1 - 0.039 13.9 1.5 0.16 11.9 1.5 2.0 1 1 0 1 1 1 0 STAT protein, all-alpha domain DUF4164 PF13747.6 EPS34468.1 - 0.056 13.7 10.0 0.42 10.9 0.7 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) LXG PF04740.12 EPS34468.1 - 0.078 12.7 0.5 6.1 6.5 0.1 2.3 2 0 0 2 2 2 0 LXG domain of WXG superfamily DUF3921 PF13060.6 EPS34468.1 - 0.09 12.8 0.1 0.41 10.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3921) Baculo_PEP_C PF04513.12 EPS34468.1 - 0.097 12.7 1.7 1.2 9.1 0.5 2.5 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4713 PF15831.5 EPS34468.1 - 0.097 13.1 1.3 0.38 11.2 1.3 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4713) KdpA PF03814.15 EPS34468.1 - 0.13 10.4 0.0 0.17 10.1 0.0 1.1 1 0 0 1 1 1 0 Potassium-transporting ATPase A subunit DUF3618 PF12277.8 EPS34468.1 - 0.33 11.2 8.4 1 9.6 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3618) DUF1664 PF07889.12 EPS34468.1 - 0.35 10.9 3.6 5.4 7.1 0.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) RRF PF01765.19 EPS34468.1 - 0.38 10.7 2.7 2.4 8.1 0.1 2.5 2 1 0 3 3 3 0 Ribosome recycling factor UPF0184 PF03670.13 EPS34468.1 - 0.56 10.6 5.2 4.5 7.7 0.0 3.6 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0184) TMF_DNA_bd PF12329.8 EPS34468.1 - 0.65 10.0 3.8 4.9 7.2 0.2 3.2 4 0 0 4 4 3 0 TATA element modulatory factor 1 DNA binding DUF16 PF01519.16 EPS34468.1 - 0.66 10.5 3.4 39 4.8 3.4 2.4 1 1 0 1 1 1 0 Protein of unknown function DUF16 Spc7 PF08317.11 EPS34468.1 - 1.2 8.0 5.0 1.6 7.5 0.9 2.1 1 1 0 2 2 2 0 Spc7 kinetochore protein UPF0242 PF06785.11 EPS34468.1 - 4.9 7.2 12.9 0.4 10.8 0.4 3.0 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus NAP PF00956.18 EPS34469.1 - 1.8e-23 83.1 17.1 7.4e-21 74.5 12.3 2.5 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) MetOD2 PF18548.1 EPS34469.1 - 0.14 12.3 0.4 0.73 10.0 0.1 2.3 2 0 0 2 2 2 0 Metanogen output domain 2 NmrA PF05368.13 EPS34470.1 - 8.4e-73 244.8 0.0 1e-72 244.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPS34470.1 - 3.2e-06 27.2 0.0 5.2e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding DUF1876 PF08962.11 EPS34470.1 - 0.053 13.5 0.2 0.12 12.4 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1876) Asparaginase PF00710.20 EPS34472.1 - 7.7e-56 188.7 0.0 1.2e-55 188.0 0.0 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 EPS34472.1 - 6.8e-30 103.6 0.3 1.6e-29 102.4 0.3 1.6 2 0 0 2 2 2 1 Glutaminase/Asparaginase C-terminal domain Ank_2 PF12796.7 EPS34472.1 - 1.5e-15 57.6 2.7 6.3e-10 39.5 0.3 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPS34472.1 - 5.7e-10 39.5 2.4 2.9e-05 24.5 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EPS34472.1 - 2.7e-09 36.5 3.0 0.0041 17.5 0.1 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EPS34472.1 - 1.1e-07 32.0 3.0 0.0024 18.3 0.3 3.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EPS34472.1 - 2.8e-07 30.7 0.2 9.9e-07 28.9 0.1 2.1 1 1 0 1 1 1 1 Ankyrin repeats (many copies) MTTB PF06253.11 EPS34472.1 - 0.018 13.1 0.3 0.027 12.5 0.3 1.1 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) Fungal_trans PF04082.18 EPS34473.1 - 1.5e-05 24.2 0.0 2.8e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain LCCL PF03815.19 EPS34474.1 - 2.3e-24 85.3 0.0 3.8e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 LCCL domain Aminotran_1_2 PF00155.21 EPS34475.1 - 2e-12 46.9 0.0 3.7e-09 36.2 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II Tannase PF07519.11 EPS34475.1 - 0.014 14.3 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Tannase and feruloyl esterase UPF0029 PF01205.19 EPS34476.1 - 1.8e-33 115.0 0.1 3.8e-33 114.0 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 EPS34476.1 - 2.8e-09 37.3 0.0 5.4e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 RWD domain Cytokin_check_N PF10407.9 EPS34476.1 - 0.018 15.0 0.0 0.036 14.0 0.0 1.4 1 0 0 1 1 1 0 Cdc14 phosphatase binding protein N-terminus EXOSC1 PF10447.9 EPS34476.1 - 0.084 13.5 0.9 0.19 12.3 0.1 1.9 2 0 0 2 2 2 0 Exosome component EXOSC1/CSL4 Glyco_hydro_61 PF03443.14 EPS34477.1 - 0.02 14.8 0.0 0.038 13.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 61 Serglycin PF04360.12 EPS34477.1 - 0.14 12.1 0.5 0.27 11.2 0.5 1.4 1 0 0 1 1 1 0 Serglycin DUF3433 PF11915.8 EPS34478.1 - 3.9e-36 123.4 9.5 8.7e-24 83.8 2.1 3.7 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) COX2_TM PF02790.15 EPS34478.1 - 0.041 14.0 0.9 2 8.6 0.0 3.0 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain Ribosomal_L4 PF00573.22 EPS34479.1 - 2.9e-38 131.5 0.5 4.5e-38 130.9 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 EPS34479.1 - 1.1e-30 105.5 1.5 1.1e-30 105.5 1.5 1.9 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain Enamelin PF15362.6 EPS34481.1 - 0.04 12.2 0.0 0.046 12.1 0.0 1.1 1 0 0 1 1 1 0 Enamelin RgpF PF05045.12 EPS34483.1 - 0.25 10.1 0.0 0.25 10.1 0.0 1.0 1 0 0 1 1 1 0 Rhamnan synthesis protein F Fungal_trans PF04082.18 EPS34484.1 - 1.6e-16 60.1 0.9 2.4e-16 59.6 0.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS34484.1 - 2.9e-07 30.5 12.8 6.4e-07 29.4 12.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3395 PF11875.8 EPS34485.1 - 2.1e-39 134.9 0.2 3.5e-39 134.2 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 EPS34485.1 - 9.3e-20 70.5 0.5 2e-19 69.5 0.5 1.6 1 0 0 1 1 1 1 DnaJ domain Acetone_carb_G PF08882.11 EPS34486.1 - 0.034 14.3 0.0 0.05 13.8 0.0 1.3 1 0 0 1 1 1 0 Acetone carboxylase gamma subunit SKIP_SNW PF02731.15 EPS34487.1 - 2.8e-72 241.6 6.1 2.8e-72 241.6 6.1 2.3 2 0 0 2 2 2 1 SKIP/SNW domain Plasmodium_Vir PF05795.11 EPS34487.1 - 1.8 7.9 3.3 3.3 7.0 3.3 1.5 1 0 0 1 1 1 0 Plasmodium vivax Vir protein FAM60A PF15396.6 EPS34487.1 - 2.1 8.3 8.2 5 7.1 8.2 1.6 1 0 0 1 1 1 0 Protein Family FAM60A Nucleo_P87 PF07267.11 EPS34487.1 - 3.5 6.4 9.3 6.2 5.6 9.3 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 AAA_32 PF13654.6 EPS34487.1 - 9.8 4.8 10.7 5.8 5.6 8.7 1.5 2 0 0 2 2 2 0 AAA domain DUF1100 PF06500.11 EPS34488.1 - 5.2e-11 42.0 0.0 6.4e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S15 PF02129.18 EPS34488.1 - 2e-07 30.9 0.0 4.2e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 EPS34488.1 - 9.1e-05 22.0 0.0 0.0002 20.9 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 EPS34488.1 - 0.00044 20.0 0.1 0.0023 17.6 0.1 2.0 1 1 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 EPS34488.1 - 0.026 13.8 0.0 0.13 11.5 0.0 2.0 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EPS34488.1 - 0.045 13.4 0.3 0.22 11.1 0.1 2.0 1 1 0 2 2 2 0 alpha/beta hydrolase fold BAAT_C PF08840.11 EPS34488.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Cu-oxidase_2 PF07731.14 EPS34489.1 - 1.4e-38 131.7 14.9 1.6e-36 125.0 1.7 3.2 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 EPS34489.1 - 2.1e-38 131.0 2.2 2.1e-38 131.0 2.2 4.0 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.22 EPS34489.1 - 3e-36 124.9 5.1 5.3e-34 117.6 0.1 3.7 4 0 0 4 4 4 2 Multicopper oxidase ACT_7 PF13840.6 EPS34490.1 - 5.5e-24 83.7 0.4 3.3e-16 58.8 0.0 3.4 3 0 0 3 3 3 3 ACT domain WD40 PF00400.32 EPS34491.1 - 2.2e-21 75.8 14.8 3.5e-05 24.5 0.6 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS34491.1 - 2.7e-08 34.0 0.1 0.24 11.7 0.0 4.6 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain VID27 PF08553.10 EPS34491.1 - 0.0017 17.5 0.0 0.0024 17.0 0.0 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain Coatomer_WDAD PF04053.14 EPS34491.1 - 0.042 12.9 0.1 0.69 8.9 0.0 2.5 2 1 1 3 3 3 0 Coatomer WD associated region DUF5046 PF16465.5 EPS34491.1 - 0.053 13.0 0.9 0.48 9.8 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5046) HydF_dimer PF18128.1 EPS34491.1 - 0.063 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Hydrogen maturase F dimerization domain Septin PF00735.18 EPS34492.1 - 6.8e-114 379.9 0.2 1e-113 379.3 0.2 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EPS34492.1 - 2.4e-07 30.8 0.0 4.8e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EPS34492.1 - 1.6e-06 28.1 0.0 3.4e-05 23.8 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EPS34492.1 - 3.9e-06 26.5 3.2 4e-05 23.2 0.3 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 EPS34492.1 - 0.00056 20.2 0.2 0.0024 18.2 0.0 2.0 2 1 0 2 2 2 1 AAA domain Pox_A32 PF04665.12 EPS34492.1 - 0.003 17.0 0.1 0.0052 16.3 0.1 1.3 1 0 0 1 1 1 1 Poxvirus A32 protein Roc PF08477.13 EPS34492.1 - 0.0063 16.7 0.1 0.013 15.7 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AIG1 PF04548.16 EPS34492.1 - 0.007 15.7 0.0 0.015 14.6 0.0 1.6 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.13 EPS34492.1 - 0.011 14.8 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_24 PF13479.6 EPS34492.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain FOXP-CC PF16159.5 EPS34492.1 - 0.02 15.5 0.6 0.071 13.7 0.6 1.9 1 0 0 1 1 1 0 FOXP coiled-coil domain AAA_16 PF13191.6 EPS34492.1 - 0.029 14.8 0.1 0.097 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain KAP_NTPase PF07693.14 EPS34492.1 - 0.029 13.6 0.0 0.047 12.9 0.0 1.6 1 1 0 1 1 1 0 KAP family P-loop domain Ras PF00071.22 EPS34492.1 - 0.046 13.3 0.7 0.13 11.8 0.4 1.9 2 1 0 2 2 2 0 Ras family NACHT PF05729.12 EPS34492.1 - 0.055 13.4 0.0 0.098 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 EPS34492.1 - 0.06 13.9 0.1 0.2 12.2 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Sigma54_activat PF00158.26 EPS34492.1 - 0.085 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain PduV-EutP PF10662.9 EPS34492.1 - 0.12 12.1 0.3 5 6.9 0.3 2.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 EPS34492.1 - 0.17 11.6 0.9 13 5.5 0.1 2.7 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 EPS34492.1 - 0.74 9.8 5.9 5.9 6.9 0.1 3.0 2 1 1 3 3 3 0 Dynamin family AAA_11 PF13086.6 EPS34492.1 - 5.4 6.7 6.6 23 4.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain APG6_N PF17675.1 EPS34492.1 - 6.1 7.4 11.2 1.3 9.6 6.9 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region WD40 PF00400.32 EPS34493.1 - 4.7e-41 138.0 22.1 1.1e-08 35.5 0.4 12.8 13 0 0 13 13 13 7 WD domain, G-beta repeat Utp12 PF04003.12 EPS34493.1 - 5e-29 100.8 0.0 7.7e-29 100.2 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 EPS34493.1 - 3.1e-22 78.7 0.0 0.005 17.1 0.0 9.8 5 2 4 10 10 10 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EPS34493.1 - 9e-10 38.8 2.6 0.077 12.9 0.1 6.7 6 1 1 7 7 7 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EPS34493.1 - 1.6e-09 37.2 0.4 0.15 11.0 0.0 4.8 2 2 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EPS34493.1 - 1.9e-08 33.5 2.1 0.81 8.2 0.1 5.3 3 1 1 5 5 5 4 Nucleoporin Nup120/160 Nbas_N PF15492.6 EPS34493.1 - 0.0022 17.4 0.3 1.3 8.3 0.0 3.5 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 EPS34493.1 - 0.0026 17.2 0.0 0.089 12.1 0.0 3.2 4 0 0 4 4 4 1 WD40-like domain PQQ_3 PF13570.6 EPS34493.1 - 0.018 15.5 6.2 5 7.7 0.2 5.7 7 0 0 7 7 7 0 PQQ-like domain IKI3 PF04762.12 EPS34493.1 - 0.031 12.3 0.1 11 3.9 0.0 3.0 2 1 0 3 3 3 0 IKI3 family PD40 PF07676.12 EPS34493.1 - 0.058 13.3 0.2 2.9 8.0 0.0 3.9 5 0 0 5 5 4 0 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 EPS34493.1 - 0.13 10.9 0.0 18 3.9 0.0 3.0 2 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region p450 PF00067.22 EPS34494.1 - 1.6e-30 106.2 0.0 4.3e-30 104.9 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 AP_endonuc_2 PF01261.24 EPS34494.1 - 0.18 11.2 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel XRN_M PF17846.1 EPS34495.1 - 2.7e-101 339.7 3.9 4.7e-101 338.9 3.9 1.3 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 EPS34495.1 - 7.4e-96 320.2 0.0 7.4e-96 320.2 0.0 1.5 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN1_D1 PF18332.1 EPS34495.1 - 3.8e-74 248.6 1.4 6.6e-74 247.8 0.0 1.9 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 EPS34495.1 - 2.8e-34 117.2 0.0 7.5e-34 115.8 0.0 1.8 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain SH3_12 PF18129.1 EPS34495.1 - 1.7e-24 85.7 0.5 4.1e-24 84.5 0.5 1.7 1 0 0 1 1 1 1 Xrn1 SH3-like domain Xrn1_D3 PF18194.1 EPS34495.1 - 2.2e-05 24.5 0.0 5.9e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 Peptidase_C92 PF05708.12 EPS34495.1 - 0.026 14.6 0.2 0.064 13.3 0.2 1.6 1 0 0 1 1 1 0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family Cwf_Cwc_15 PF04889.12 EPS34495.1 - 0.03 14.0 3.5 0.052 13.3 3.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF1345 PF07077.11 EPS34495.1 - 0.083 12.6 0.1 0.17 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1345) WD40 PF00400.32 EPS34496.1 - 1.6e-28 98.4 10.8 2.6e-06 28.0 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 EPS34496.1 - 4e-28 97.5 0.5 1.8e-27 95.4 0.4 2.2 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 EPS34496.1 - 1.6e-06 28.3 1.3 0.19 12.0 0.1 4.9 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3751 PF12571.8 EPS34496.1 - 0.00074 19.6 0.1 0.077 13.1 0.0 2.4 2 0 0 2 2 2 1 Phage tail-collar fibre protein Nup160 PF11715.8 EPS34496.1 - 0.027 13.1 0.7 11 4.5 0.1 3.6 2 1 2 4 4 4 0 Nucleoporin Nup120/160 GTP_cyclohydroI PF01227.22 EPS34497.1 - 2e-73 245.6 0.3 2.9e-73 245.1 0.3 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 EPS34497.1 - 0.01 16.0 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 0 QueF-like protein Pkinase PF00069.25 EPS34498.1 - 8.7e-69 231.8 0.0 1.1e-68 231.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS34498.1 - 1.5e-34 119.5 0.0 5.1e-34 117.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EPS34498.1 - 0.017 14.4 0.0 0.037 13.3 0.0 1.4 1 1 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 EPS34498.1 - 0.017 13.9 0.0 0.017 13.9 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase Kdo PF06293.14 EPS34498.1 - 0.077 12.3 0.5 0.21 10.9 0.5 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EPS34498.1 - 0.17 10.8 0.1 1.3 7.9 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain IF4E PF01652.18 EPS34500.1 - 1.1e-54 184.5 0.0 1.9e-54 183.8 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Peptidase_C48 PF02902.19 EPS34501.1 - 1.8e-31 109.7 0.0 8.8e-31 107.4 0.0 2.1 2 1 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain MAAL_N PF05034.13 EPS34501.1 - 0.2 11.3 0.0 0.37 10.4 0.0 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase N-terminus GGACT PF06094.12 EPS34502.1 - 4.1e-16 59.7 0.2 7.6e-16 58.8 0.2 1.4 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like SPC22 PF04573.12 EPS34503.1 - 4.4e-39 133.7 0.1 6.3e-28 97.4 0.1 2.2 2 0 0 2 2 2 2 Signal peptidase subunit Pmp3 PF01679.17 EPS34504.1 - 4.5e-22 78.0 9.2 5.6e-22 77.7 9.2 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator SNARE_assoc PF09335.11 EPS34504.1 - 0.036 14.5 0.0 0.044 14.3 0.0 1.2 1 0 0 1 1 1 0 SNARE associated Golgi protein BCDHK_Adom3 PF10436.9 EPS34505.1 - 5.3e-46 156.4 0.1 1.8e-45 154.7 0.1 1.8 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 EPS34505.1 - 2.3e-05 24.8 0.0 7.8e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 EPS34505.1 - 0.15 12.0 0.0 1.5 8.8 0.0 2.2 1 1 1 2 2 2 0 Histidine kinase-like ATPase domain USP7_ICP0_bdg PF12436.8 EPS34506.1 - 3.9e-87 291.5 1.9 7.8e-86 287.3 0.3 2.3 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.6 EPS34506.1 - 1.9e-72 243.3 2.4 2.6e-70 236.3 0.0 3.5 3 1 1 4 4 4 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 EPS34506.1 - 8.2e-49 166.4 0.2 1.4e-48 165.6 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EPS34506.1 - 3.4e-20 72.9 0.0 1.1e-19 71.3 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 EPS34506.1 - 2.7e-08 33.9 0.0 7.2e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 MATH domain Rad60-SLD PF11976.8 EPS34506.1 - 0.00047 19.9 2.3 3.4 7.6 0.1 4.3 3 1 0 3 3 3 2 Ubiquitin-2 like Rad60 SUMO-like Imm45 PF15572.6 EPS34506.1 - 0.11 12.9 0.0 0.85 10.0 0.0 2.4 2 0 0 2 2 2 0 Immunity protein 45 EMP24_GP25L PF01105.24 EPS34507.1 - 1.9e-48 164.8 4.1 2.2e-48 164.6 4.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD IrmA PF18673.1 EPS34507.1 - 0.08 13.1 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 interleukin receptor mimic protein A DUF2012 PF09430.10 EPS34507.1 - 0.087 12.9 0.2 0.23 11.6 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2012) GHD PF17834.1 EPS34507.1 - 0.18 11.9 2.0 0.28 11.2 0.3 2.0 2 0 0 2 2 2 0 Beta-sandwich domain in beta galactosidase Hep_59 PF07052.11 EPS34509.1 - 0.022 15.5 0.7 0.037 14.8 0.7 1.4 1 0 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 Cactin_mid PF10312.9 EPS34509.1 - 0.11 12.1 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Conserved mid region of cactin Hydrophobin PF01185.18 EPS34510.1 - 3.7e-05 24.3 3.9 5.3e-05 23.8 3.9 1.3 1 0 0 1 1 1 1 Fungal hydrophobin Fungal_trans_2 PF11951.8 EPS34511.1 - 2.7e-11 42.9 0.7 4.7e-11 42.1 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS34511.1 - 4e-09 36.4 9.8 7.1e-09 35.7 9.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CTD_bind PF04818.13 EPS34513.1 - 3.8e-10 40.4 0.0 9e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Glyco_hydro_11 PF00457.17 EPS34514.1 - 9.5e-55 185.0 7.2 1.1e-54 184.7 7.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 S19 PF06756.11 EPS34515.1 - 0.048 13.6 0.4 0.097 12.6 0.4 1.6 1 1 0 1 1 1 0 Chorion protein S19 C-terminal DUF4748 PF15932.5 EPS34517.1 - 7.5e-23 80.0 0.9 1.4e-22 79.2 0.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4748) ERCC3_RAD25_C PF16203.5 EPS34518.1 - 7.1e-124 411.9 1.1 1.5e-123 410.8 1.1 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 EPS34518.1 - 9.7e-36 122.7 0.0 2e-35 121.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EPS34518.1 - 6.4e-17 62.1 0.0 1.3e-16 61.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EPS34518.1 - 1.6e-13 50.9 0.2 3.5e-13 49.9 0.2 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EPS34518.1 - 4e-09 35.6 0.0 5e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 EPS34518.1 - 0.00072 19.4 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.6 EPS34518.1 - 0.0028 16.6 0.0 0.0048 15.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Questin_oxidase PF14027.6 EPS34520.1 - 1.8e-99 333.5 0.1 2.1e-99 333.3 0.1 1.1 1 0 0 1 1 1 1 Questin oxidase-like CN_hydrolase PF00795.22 EPS34522.1 - 6.8e-44 150.2 0.0 9e-44 149.8 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 EPS34522.1 - 4.7e-22 78.3 0.0 2.2e-21 76.1 0.0 1.9 1 1 0 1 1 1 1 NAD synthase DNA_pol3_gamma3 PF12169.8 EPS34522.1 - 0.048 13.6 0.0 0.091 12.7 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III subunits gamma and tau domain III NUDIX-like PF09296.11 EPS34523.1 - 5.1e-20 72.0 0.0 1.6e-19 70.5 0.0 1.8 2 1 0 2 2 2 1 NADH pyrophosphatase-like rudimentary NUDIX domain NUDIX PF00293.28 EPS34523.1 - 2.9e-17 62.9 0.1 5.6e-17 62.0 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.11 EPS34523.1 - 9.8e-06 25.1 1.8 2.1e-05 24.1 1.8 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain DpnI PF06044.12 EPS34523.1 - 0.088 12.4 0.1 2.2 7.9 0.1 2.6 3 0 0 3 3 3 0 Dam-replacing family POT1 PF02765.17 EPS34524.1 - 4.9e-14 52.4 0.0 1.1e-13 51.2 0.0 1.7 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 FMO-like PF00743.19 EPS34525.1 - 8.6e-41 139.9 0.0 5.2e-26 91.2 0.0 3.0 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 EPS34525.1 - 4.4e-11 42.6 0.0 6.3e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EPS34525.1 - 8.7e-11 41.6 0.0 4.6e-08 32.7 0.0 3.1 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EPS34525.1 - 4.6e-10 39.2 0.2 1.1e-07 31.4 0.0 2.7 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EPS34525.1 - 4.8e-10 39.6 0.0 4.4e-09 36.5 0.0 2.4 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.24 EPS34525.1 - 7.1e-07 29.1 0.8 0.042 13.4 0.3 3.2 1 1 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.17 EPS34525.1 - 3.1e-05 23.3 0.3 0.0013 18.0 0.1 2.2 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 EPS34525.1 - 0.00015 21.9 0.1 0.00039 20.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EPS34525.1 - 0.056 12.1 0.1 0.65 8.6 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.24 EPS34525.1 - 0.069 12.2 0.0 3.4 6.6 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Pyr_redox PF00070.27 EPS34525.1 - 0.12 13.0 0.2 29 5.3 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HDA2-3 PF11496.8 EPS34526.1 - 2.5e-37 128.7 0.0 1.2e-35 123.1 0.0 2.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 CENP-F_leu_zip PF10473.9 EPS34526.1 - 0.12 12.4 48.5 0.22 11.5 9.2 4.1 1 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 EPS34526.1 - 0.22 11.7 47.1 0.61 10.3 17.4 2.4 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) DUF515 PF04415.12 EPS34526.1 - 0.24 9.8 7.2 0.38 9.1 7.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Filament PF00038.21 EPS34526.1 - 3.9 7.0 39.0 17 4.9 39.0 2.0 1 1 0 1 1 1 0 Intermediate filament protein ketoacyl-synt PF00109.26 EPS34527.1 - 1.7e-81 273.5 0.0 3.2e-81 272.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SAT PF16073.5 EPS34527.1 - 3.3e-80 269.3 0.2 3.3e-80 269.3 0.2 2.3 3 0 0 3 3 3 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Acyl_transf_1 PF00698.21 EPS34527.1 - 3.3e-47 161.6 0.0 5.5e-47 160.8 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EPS34527.1 - 2.7e-35 120.9 0.1 6.1e-35 119.8 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 EPS34527.1 - 2.4e-24 85.5 4.8 1.1e-11 44.9 0.6 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site Thioesterase PF00975.20 EPS34527.1 - 1.2e-19 71.3 0.0 1.4e-18 67.9 0.0 2.9 2 1 0 2 2 2 1 Thioesterase domain PS-DH PF14765.6 EPS34527.1 - 4.5e-16 59.0 0.0 8.1e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.23 EPS34527.1 - 0.00017 21.0 0.0 0.00037 20.0 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_6 PF12697.7 EPS34527.1 - 0.00031 21.4 0.2 0.011 16.3 0.0 2.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family KAsynt_C_assoc PF16197.5 EPS34527.1 - 0.00033 21.1 0.0 0.001 19.5 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Cu-oxidase_3 PF07732.15 EPS34528.1 - 1.2e-41 141.4 0.7 2.5e-41 140.4 0.7 1.6 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 EPS34528.1 - 4.3e-26 91.3 11.5 1.7e-21 76.4 0.6 3.6 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.22 EPS34528.1 - 1.9e-22 80.1 0.0 2.4e-21 76.5 0.0 2.3 2 0 0 2 2 2 1 Multicopper oxidase Transglut_core PF01841.19 EPS34530.1 - 5.7e-09 36.4 0.0 1.3e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.17 EPS34530.1 - 5.9e-08 32.3 0.0 1.5e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EPS34530.1 - 7.8e-07 28.6 0.9 4e-06 26.3 0.0 2.4 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EPS34530.1 - 0.0043 16.9 1.5 0.015 15.2 0.1 2.5 3 0 0 3 3 3 1 Variant SH3 domain DHHA2 PF02833.14 EPS34531.1 - 5.3e-33 114.2 0.5 7.8e-33 113.7 0.5 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 EPS34531.1 - 8.4e-07 29.2 0.0 1.4e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 DHH family adh_short PF00106.25 EPS34532.1 - 3.6e-20 72.3 0.1 1.4e-13 50.7 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EPS34532.1 - 1e-12 48.1 0.0 3.2e-06 26.9 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 EPS34532.1 - 8e-08 32.4 0.0 1.3e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EPS34532.1 - 0.0031 17.0 0.0 0.0046 16.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EPS34532.1 - 0.0033 17.4 0.1 0.0069 16.3 0.1 1.5 1 0 0 1 1 1 1 KR domain PALP PF00291.25 EPS34533.1 - 2.1e-33 116.0 0.0 2.7e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PLU-1 PF08429.11 EPS34534.1 - 3e-109 365.3 21.0 1e-105 353.7 19.2 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.22 EPS34534.1 - 4.1e-43 146.4 0.1 9.2e-43 145.3 0.1 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.21 EPS34534.1 - 5.3e-21 75.1 0.0 1.5e-20 73.6 0.0 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 EPS34534.1 - 2e-17 62.9 1.9 5.4e-17 61.5 1.9 1.8 1 0 0 1 1 1 1 jmjN domain PHD PF00628.29 EPS34534.1 - 3.4e-16 58.9 33.6 1.1e-08 34.8 8.3 3.5 3 0 0 3 3 3 2 PHD-finger zf-C5HC2 PF02928.16 EPS34534.1 - 1.3e-13 51.1 6.9 1.3e-13 51.1 6.9 2.2 2 0 0 2 2 1 1 C5HC2 zinc finger PHD_2 PF13831.6 EPS34534.1 - 0.0022 17.5 3.3 0.0022 17.5 3.3 2.8 3 0 0 3 3 3 1 PHD-finger DUF4376 PF14301.6 EPS34534.1 - 0.015 15.6 3.0 0.047 14.1 3.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4376) DUF1854 PF08909.11 EPS34534.1 - 0.055 13.3 0.0 2.2 8.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1854) zf-PHD-like PF15446.6 EPS34534.1 - 0.33 10.5 15.4 0.064 12.9 1.8 2.9 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain PHD_4 PF16866.5 EPS34534.1 - 0.4 10.8 19.5 1.2 9.3 5.1 3.0 2 0 0 2 2 2 0 PHD-finger C1_1 PF00130.22 EPS34534.1 - 0.42 10.5 21.7 0.12 12.3 0.9 3.5 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H_2 PF13832.6 EPS34534.1 - 0.47 10.6 11.6 1 9.6 2.7 2.7 2 0 0 2 2 2 0 PHD-zinc-finger like domain Spore_III_AB PF09548.10 EPS34534.1 - 10 6.2 11.9 17 5.5 5.3 2.8 2 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) GIY-YIG PF01541.24 EPS34535.1 - 1.8e-12 47.4 0.0 3.7e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 GIY-YIG catalytic domain FANCL_C PF11793.8 EPS34535.1 - 2.2e-05 24.5 3.8 4e-05 23.7 3.8 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-HC5HC2H PF13771.6 EPS34535.1 - 0.0017 18.6 2.5 0.0034 17.6 2.5 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 EPS34535.1 - 0.0048 17.1 1.8 0.0087 16.2 1.8 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain Thymidylate_kin PF02223.17 EPS34536.1 - 4.9e-46 156.7 0.0 5.7e-46 156.5 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.10 EPS34536.1 - 0.005 16.3 0.1 0.019 14.5 0.0 1.8 2 1 0 2 2 2 1 Chromatin associated protein KTI12 CPT PF07931.12 EPS34536.1 - 0.064 13.1 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein TGT PF01702.18 EPS34537.1 - 2.5e-66 224.2 0.0 3.2e-66 223.9 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase MTHFR PF02219.17 EPS34538.1 - 8.4e-97 323.9 0.0 1.2e-96 323.4 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase FLILHELTA PF10306.9 EPS34539.1 - 2.4e-30 104.8 0.0 4.3e-30 104.0 0.0 1.4 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.13 EPS34539.1 - 0.0017 18.9 0.0 0.0028 18.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) NDK PF00334.19 EPS34540.1 - 4.9e-54 182.0 0.0 5.6e-54 181.8 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Glyco_hydro_31 PF01055.26 EPS34541.1 - 4.7e-137 457.8 6.1 6.3e-137 457.3 6.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EPS34541.1 - 4.3e-27 94.2 1.0 3.1e-26 91.5 0.3 2.5 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 EPS34541.1 - 1.1e-06 28.8 0.9 3.4e-06 27.2 0.9 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) LcrR PF09621.10 EPS34541.1 - 0.15 11.5 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 Type III secretion system regulator (LcrR) PQ-loop PF04193.14 EPS34542.1 - 1.5e-22 79.1 1.8 2.1e-13 49.8 0.1 2.6 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 EPS34542.1 - 4.4e-05 24.3 3.1 0.00029 21.7 3.0 2.0 1 1 0 1 1 1 1 ER lumen protein retaining receptor NMT1 PF09084.11 EPS34543.1 - 0.0038 17.2 0.0 0.02 14.8 0.0 2.1 2 1 0 2 2 2 1 NMT1/THI5 like NMT1_2 PF13379.6 EPS34543.1 - 0.055 13.2 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 NMT1-like family NMT1_3 PF16868.5 EPS34543.1 - 0.13 11.7 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 NMT1-like family SBP_bac_3 PF00497.20 EPS34543.1 - 0.16 11.4 0.0 19 4.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 Glyco_hydro_18 PF00704.28 EPS34544.1 - 2.3e-21 76.9 0.5 2.3e-21 76.9 0.5 2.0 2 1 0 2 2 2 1 Glycosyl hydrolases family 18 E1-E2_ATPase PF00122.20 EPS34545.1 - 9.7e-33 113.2 8.6 4.5e-22 78.5 0.4 3.6 3 0 0 3 3 3 2 E1-E2 ATPase Hydrolase PF00702.26 EPS34545.1 - 1.1e-17 65.1 0.0 3.2e-17 63.5 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EPS34545.1 - 1.2e-09 37.7 0.0 2.7e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EPS34545.1 - 0.0022 17.8 0.1 0.03 14.0 0.0 2.5 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EPS34545.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Cation transport ATPase (P-type) TM_helix PF05552.12 EPS34545.1 - 0.12 12.4 2.5 0.46 10.5 2.5 2.0 1 0 0 1 1 1 0 Conserved TM helix GNVR PF13807.6 EPS34545.1 - 0.14 12.1 0.0 0.61 10.1 0.0 2.1 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase tRNA-synt_1c PF00749.21 EPS34546.1 - 4.4e-105 351.0 0.0 5.9e-105 350.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EPS34546.1 - 1.7e-40 138.8 0.2 4.1e-40 137.5 0.2 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_2 PF13410.6 EPS34546.1 - 0.00074 19.5 0.1 0.0025 17.8 0.1 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EPS34546.1 - 0.038 14.2 0.1 0.095 12.9 0.1 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 EPS34546.1 - 0.086 12.2 0.3 0.22 10.8 0.1 1.5 1 1 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Glutaredoxin2_C PF04399.13 EPS34546.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Ribosomal_L1 PF00687.21 EPS34547.1 - 4.5e-30 104.9 0.0 5.3e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family COG2 PF06148.11 EPS34548.1 - 2.5e-35 121.4 0.8 4.2e-35 120.7 0.8 1.3 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 EPS34548.1 - 7.3e-06 26.0 0.2 3e-05 24.0 0.2 2.1 2 1 0 2 2 2 1 Vps51/Vps67 Bcr-Abl_Oligo PF09036.10 EPS34548.1 - 0.0076 16.2 0.2 0.024 14.6 0.1 1.9 2 0 0 2 2 2 1 Bcr-Abl oncoprotein oligomerisation domain Helo_like_N PF17111.5 EPS34548.1 - 0.029 13.8 0.3 0.051 12.9 0.3 1.4 1 0 0 1 1 1 0 Fungal N-terminal domain of STAND proteins DUF2046 PF09755.9 EPS34548.1 - 0.054 12.7 3.1 0.09 12.0 3.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) CDT1 PF08839.11 EPS34548.1 - 0.14 12.4 0.1 13 6.0 0.0 2.2 2 0 0 2 2 2 0 DNA replication factor CDT1 like UPF0242 PF06785.11 EPS34548.1 - 1.3 9.1 5.9 31 4.6 5.9 2.1 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Zwint PF15556.6 EPS34548.1 - 1.4 8.3 6.1 1.3 8.4 1.2 2.1 1 1 0 2 2 2 0 ZW10 interactor ParA PF10609.9 EPS34550.1 - 9.8e-86 287.2 0.4 7.5e-84 281.0 0.4 2.2 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EPS34550.1 - 1.5e-10 41.2 0.0 4.5e-10 39.7 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.11 EPS34550.1 - 7.9e-07 28.6 0.0 9.2e-06 25.1 0.0 2.0 1 1 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.6 EPS34550.1 - 7.4e-06 26.0 0.3 0.00029 20.8 0.3 2.1 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 EPS34550.1 - 0.00015 21.0 0.7 0.00035 19.9 0.7 1.5 1 0 0 1 1 1 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 EPS34550.1 - 0.00091 18.8 0.2 0.051 13.0 0.1 2.1 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ AAA_25 PF13481.6 EPS34550.1 - 0.0011 18.5 0.2 0.002 17.8 0.2 1.3 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 EPS34550.1 - 0.012 14.6 0.5 0.019 14.0 0.5 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_26 PF13500.6 EPS34550.1 - 0.016 15.0 1.9 3.4 7.4 0.6 2.4 2 1 0 2 2 2 0 AAA domain APS_kinase PF01583.20 EPS34550.1 - 0.093 12.6 0.1 0.15 11.9 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Fer4_NifH PF00142.18 EPS34550.1 - 0.12 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CENP-B_dimeris PF09026.10 EPS34550.1 - 0.95 9.9 6.5 1.7 9.1 6.5 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain SEP PF08059.13 EPS34551.1 - 1.7e-24 86.2 0.1 3.7e-24 85.1 0.1 1.6 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 EPS34551.1 - 8.4e-16 57.9 0.0 1.4e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 EPS34551.1 - 1.1e-13 50.7 0.2 1.9e-13 50.0 0.2 1.4 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 EPS34551.1 - 0.00066 19.3 0.1 0.0011 18.5 0.1 1.3 1 0 0 1 1 1 1 TAP C-terminal domain TOM13 PF08219.11 EPS34552.1 - 2e-35 120.6 0.0 2.7e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 60KD_IMP PF02096.20 EPS34553.1 - 2.7e-15 56.6 0.1 2.7e-15 56.6 0.1 1.8 2 0 0 2 2 2 1 60Kd inner membrane protein REC1 PF18501.1 EPS34553.1 - 1.3 8.9 5.0 2.5 7.9 5.0 1.4 1 0 0 1 1 1 0 Alpha helical recognition lobe domain TAFII28 PF04719.14 EPS34554.1 - 1.2e-24 86.2 3.2 9.4e-24 83.3 0.6 2.2 2 0 0 2 2 2 1 hTAFII28-like protein conserved region SRP-alpha_N PF04086.13 EPS34554.1 - 0.16 11.8 9.0 0.028 14.3 3.4 2.0 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal SAM_decarbox PF01536.16 EPS34555.1 - 5.2e-132 440.1 0.0 6.2e-132 439.9 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase TAF6_C PF07571.13 EPS34556.1 - 8.9e-32 109.3 0.0 2.7e-31 107.8 0.0 1.9 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 EPS34556.1 - 4.9e-26 90.7 0.0 2e-25 88.7 0.0 2.0 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 EPS34556.1 - 0.00074 19.9 0.1 0.0042 17.4 0.1 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 EPS34556.1 - 0.014 15.5 0.1 0.039 14.0 0.1 1.7 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 EPS34556.1 - 0.024 14.9 0.2 0.28 11.5 0.0 2.5 3 0 0 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CRAL_TRIO PF00650.20 EPS34557.1 - 1.6e-17 63.7 0.0 3e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EPS34557.1 - 1.7e-10 40.9 0.0 3.8e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain IPP-2 PF04979.14 EPS34558.1 - 9e-21 75.0 21.2 9e-21 75.0 21.2 2.5 2 1 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) CAF1A PF12253.8 EPS34561.1 - 4.5e-23 81.2 6.6 4.5e-23 81.2 6.6 3.9 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.8 EPS34561.1 - 0.15 11.8 61.6 0.3 10.8 61.6 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Cwf_Cwc_15 PF04889.12 EPS34561.1 - 3.1 7.5 46.4 0.025 14.3 3.1 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein PPP4R2 PF09184.11 EPS34561.1 - 5.1 6.6 41.9 0.16 11.5 29.4 2.4 2 0 0 2 2 2 0 PPP4R2 CDC27 PF09507.10 EPS34561.1 - 7.9 5.8 48.3 0.057 12.8 37.9 2.4 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Borrelia_P83 PF05262.11 EPS34561.1 - 8.6 4.7 35.7 14 4.0 35.7 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein CoA_transf_3 PF02515.17 EPS34567.1 - 6.6e-66 222.9 0.0 1.7e-65 221.6 0.0 1.5 1 1 0 1 1 1 1 CoA-transferase family III Tudor_2 PF18104.1 EPS34567.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Jumonji domain-containing protein 2A Tudor domain Glyco_hydro_18 PF00704.28 EPS34568.1 - 4e-21 76.1 0.0 7.3e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Sugar_tr PF00083.24 EPS34570.1 - 1.6e-80 271.2 27.2 1.9e-80 270.9 27.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS34570.1 - 6.2e-25 87.9 51.4 5e-20 71.7 21.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EPS34570.1 - 7.2e-07 28.0 1.9 7.2e-07 28.0 1.9 2.4 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_1 PF00232.18 EPS34571.1 - 6.9e-149 496.1 0.1 8e-149 495.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_cc PF11790.8 EPS34571.1 - 6.7e-05 22.6 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Fungal_trans PF04082.18 EPS34572.1 - 2.4e-09 36.6 0.3 3.8e-07 29.4 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS34572.1 - 7.9e-06 25.9 10.5 1.3e-05 25.2 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4396 PF14342.6 EPS34574.1 - 0.069 13.5 0.4 0.14 12.5 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4396) HCV_env PF01539.17 EPS34575.1 - 0.12 12.0 0.8 0.84 9.3 0.8 2.0 1 1 0 1 1 1 0 Hepatitis C virus envelope glycoprotein E1 Fez1 PF06818.15 EPS34576.1 - 2.6e-05 24.8 23.2 2.6e-05 24.8 23.2 4.5 1 1 2 3 3 3 1 Fez1 CCDC144C PF14915.6 EPS34576.1 - 0.0025 17.0 8.6 0.0025 17.0 8.6 3.3 3 0 0 3 3 3 1 CCDC144C protein coiled-coil region SlyX PF04102.12 EPS34576.1 - 0.013 16.1 0.8 0.013 16.1 0.8 9.3 4 2 5 9 9 9 0 SlyX Packaging_FI PF14000.6 EPS34576.1 - 0.013 15.9 4.5 0.013 15.9 4.5 4.2 2 2 1 4 4 4 0 DNA packaging protein FI HIP1_clath_bdg PF16515.5 EPS34576.1 - 0.013 16.0 15.7 0.013 16.0 15.7 7.3 2 2 9 11 11 11 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DivIC PF04977.15 EPS34576.1 - 0.014 15.1 5.4 0.014 15.1 5.4 9.6 4 2 5 9 9 9 0 Septum formation initiator CinA_KH PF18146.1 EPS34576.1 - 4 7.7 9.5 3 8.1 0.2 4.2 3 0 0 3 3 3 0 Damage-inducible protein CinA KH domain WD40_alt PF14077.6 EPS34576.1 - 7.8 6.4 12.9 1.8 8.5 0.2 4.6 5 0 0 5 5 5 0 Alternative WD40 repeat motif KGG PF10685.9 EPS34577.1 - 0.00021 21.5 0.2 0.00021 21.5 0.2 2.3 2 0 0 2 2 2 1 Stress-induced bacterial acidophilic repeat motif Glyco_hydro_18 PF00704.28 EPS34578.1 - 1e-11 45.1 0.0 1.3e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PhoD PF09423.10 EPS34579.1 - 8.9e-36 123.6 0.0 2.3e-35 122.3 0.0 1.6 1 1 0 1 1 1 1 PhoD-like phosphatase PhoD_N PF16655.5 EPS34579.1 - 0.0031 18.0 0.0 0.016 15.7 0.0 2.1 2 0 0 2 2 2 1 PhoD-like phosphatase, N-terminal domain Pur_ac_phosph_N PF16656.5 EPS34579.1 - 0.0041 17.7 0.1 0.0099 16.4 0.1 1.6 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain fn3 PF00041.21 EPS34579.1 - 0.079 13.3 0.4 0.22 11.9 0.4 1.7 1 0 0 1 1 1 0 Fibronectin type III domain SRP54 PF00448.22 EPS34580.1 - 2.2e-74 249.4 2.2 4.6e-74 248.3 2.1 1.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 EPS34580.1 - 6.9e-30 103.6 0.8 6.9e-30 103.6 0.8 4.0 4 1 1 5 5 3 1 Signal peptide binding domain SRP54_N PF02881.19 EPS34580.1 - 5.4e-21 74.6 1.2 1.7e-20 73.0 1.2 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 EPS34580.1 - 7.6e-08 32.1 0.3 2.5e-07 30.4 0.2 2.0 2 0 0 2 2 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EPS34580.1 - 2.6e-06 27.7 0.3 2.4e-05 24.5 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 EPS34580.1 - 7.2e-06 26.5 0.1 2.8e-05 24.6 0.1 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EPS34580.1 - 1.4e-05 25.5 0.0 3.9e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.12 EPS34580.1 - 0.0003 20.1 0.1 0.00064 19.0 0.1 1.5 1 0 0 1 1 1 1 Zeta toxin MeaB PF03308.16 EPS34580.1 - 0.00041 19.4 0.2 0.00041 19.4 0.2 2.9 2 2 1 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB APS_kinase PF01583.20 EPS34580.1 - 0.00093 19.1 0.0 0.0021 18.0 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase CbiA PF01656.23 EPS34580.1 - 0.0012 18.9 0.0 0.0037 17.3 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 EPS34580.1 - 0.0024 17.6 0.4 0.0024 17.6 0.4 1.9 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 EPS34580.1 - 0.003 17.4 0.9 0.015 15.1 0.1 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein ResIII PF04851.15 EPS34580.1 - 0.0035 17.4 0.6 0.025 14.6 0.6 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EPS34580.1 - 0.0047 17.2 0.1 0.016 15.5 0.1 2.0 1 0 0 1 1 1 1 AAA domain 6PF2K PF01591.18 EPS34580.1 - 0.0052 16.1 0.0 0.0097 15.2 0.0 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase SRPRB PF09439.10 EPS34580.1 - 0.0059 16.1 0.9 1.9 7.9 0.6 3.3 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_28 PF13521.6 EPS34580.1 - 0.0069 16.6 0.1 0.017 15.4 0.1 1.8 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EPS34580.1 - 0.0084 15.8 0.1 0.028 14.1 0.1 1.9 1 0 0 1 1 1 1 Thymidylate kinase MobB PF03205.14 EPS34580.1 - 0.011 15.7 0.1 0.029 14.3 0.1 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 EPS34580.1 - 0.011 16.2 0.1 0.031 14.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain MMR_HSR1 PF01926.23 EPS34580.1 - 0.022 14.9 0.1 0.081 13.0 0.1 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_31 PF13614.6 EPS34580.1 - 0.023 14.6 0.4 0.23 11.4 0.3 2.4 1 1 0 1 1 1 0 AAA domain Arf PF00025.21 EPS34580.1 - 0.07 12.6 0.1 0.28 10.6 0.0 2.0 3 0 0 3 3 3 0 ADP-ribosylation factor family AAA_24 PF13479.6 EPS34580.1 - 0.086 12.6 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EPS34580.1 - 0.12 12.9 1.1 0.39 11.2 0.1 2.4 2 1 0 2 2 2 0 ABC transporter GET2 PF08690.10 EPS34580.1 - 0.73 9.5 3.8 1.4 8.5 3.8 1.5 1 0 0 1 1 1 0 GET complex subunit GET2 Rrp15p PF07890.12 EPS34581.1 - 4e-38 130.8 7.9 4e-38 130.8 7.9 2.3 2 1 0 2 2 2 1 Rrp15p Fer2 PF00111.27 EPS34582.1 - 1.3e-14 53.9 0.8 1.7e-14 53.5 0.8 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Flagellin_IN PF07196.13 EPS34582.1 - 0.21 11.8 0.3 0.35 11.1 0.3 1.3 1 0 0 1 1 1 0 Flagellin hook IN motif Mito_carr PF00153.27 EPS34583.1 - 1.1e-11 44.5 4.4 0.022 14.7 0.0 5.0 3 2 0 3 3 3 3 Mitochondrial carrier protein Hap4_Hap_bind PF10297.9 EPS34584.1 - 1.2e-08 34.8 6.9 1.2e-08 34.8 6.9 2.5 2 0 0 2 2 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.21 EPS34584.1 - 0.00024 21.1 14.3 0.00024 21.1 14.3 3.0 2 1 2 4 4 3 2 bZIP transcription factor FAM184 PF15665.5 EPS34584.1 - 0.004 16.9 7.7 0.0075 16.1 7.7 1.4 1 0 0 1 1 1 1 Family with sequence similarity 184, A and B DUF812 PF05667.11 EPS34584.1 - 0.0083 15.1 6.0 0.013 14.4 6.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF812) IFT57 PF10498.9 EPS34584.1 - 0.017 14.1 1.0 0.025 13.5 1.0 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF3450 PF11932.8 EPS34584.1 - 0.065 12.5 6.8 0.12 11.6 6.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF2408 PF10303.9 EPS34584.1 - 0.092 13.3 1.5 0.19 12.3 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Filament PF00038.21 EPS34584.1 - 0.14 11.7 9.1 0.23 11.0 9.1 1.2 1 0 0 1 1 1 0 Intermediate filament protein dsrm PF00035.26 EPS34584.1 - 0.14 12.9 0.0 0.3 11.8 0.0 1.4 1 0 0 1 1 1 0 Double-stranded RNA binding motif MTD PF01993.18 EPS34584.1 - 0.26 10.6 0.8 1.2 8.4 0.0 2.0 2 0 0 2 2 2 0 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase Phlebovirus_NSM PF07246.11 EPS34584.1 - 0.6 9.4 3.6 1.1 8.6 3.6 1.4 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF3584 PF12128.8 EPS34584.1 - 0.63 7.5 8.8 0.9 7.0 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Fmp27_WPPW PF10359.9 EPS34584.1 - 1.1 8.1 4.7 1.6 7.5 4.7 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain FlaC_arch PF05377.11 EPS34584.1 - 1.1 9.7 2.4 3.4 8.2 0.2 2.1 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) TMPIT PF07851.13 EPS34584.1 - 1.4 8.1 3.2 2.1 7.5 3.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein Golgin_A5 PF09787.9 EPS34584.1 - 1.8 8.0 8.8 4.1 6.8 8.8 1.5 1 0 0 1 1 1 0 Golgin subfamily A member 5 Sec2p PF06428.11 EPS34584.1 - 1.8 8.6 7.0 7.6 6.6 1.9 2.4 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p TEX13 PF15186.6 EPS34584.1 - 1.8 8.2 8.6 3.7 7.2 8.6 1.4 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family AAA_13 PF13166.6 EPS34584.1 - 1.9 7.0 6.7 2.9 6.4 6.7 1.2 1 0 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.15 EPS34584.1 - 2.7 7.5 5.5 6.6 6.2 4.2 1.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit FUSC PF04632.12 EPS34584.1 - 8 4.9 5.4 12 4.3 5.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family ADH_N PF08240.12 EPS34585.1 - 1.1e-27 96.1 3.0 3.9e-27 94.3 2.3 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPS34585.1 - 1.2e-06 28.6 0.1 0.0041 17.1 0.0 2.5 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N_assoc PF13823.6 EPS34585.1 - 1.8e-05 24.6 1.7 1.8e-05 24.6 1.7 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated Peptidase_M18 PF02127.15 EPS34586.1 - 1.6e-133 445.7 0.0 1.8e-133 445.5 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) PIN_6 PF17146.4 EPS34588.1 - 2e-30 105.1 0.0 5.6e-30 103.7 0.0 1.8 1 0 0 1 1 1 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 EPS34588.1 - 9.4e-30 102.6 4.5 1.7e-29 101.7 4.5 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zf-NADH-PPase PF09297.11 EPS34588.1 - 0.47 10.1 2.6 0.34 10.6 0.3 2.0 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Nop14 PF04147.12 EPS34588.1 - 0.63 8.2 14.6 0.9 7.7 14.6 1.3 1 0 0 1 1 1 0 Nop14-like family FGF-BP1 PF06473.12 EPS34588.1 - 0.78 9.5 10.6 1.5 8.6 10.6 1.5 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Nop10p PF04135.12 EPS34589.1 - 3.5e-21 75.0 0.6 4.1e-21 74.8 0.6 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family tRNA_int_endo PF01974.17 EPS34590.1 - 3e-20 72.1 0.1 7.4e-20 70.8 0.1 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 EPS34590.1 - 1.3e-07 31.2 0.0 0.0012 18.4 0.0 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Rad9_Rad53_bind PF08605.10 EPS34591.1 - 1.9e-24 86.3 0.0 3.1e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding Tudor_3 PF18115.1 EPS34591.1 - 2.2e-18 65.8 0.1 5.7e-18 64.5 0.1 1.8 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain BRCT PF00533.26 EPS34591.1 - 1.3e-09 38.3 0.0 4.5e-09 36.6 0.0 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EPS34591.1 - 2.2e-07 31.2 0.0 6.5e-07 29.7 0.0 1.9 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 EPS34591.1 - 8.2e-05 22.4 0.0 0.00024 20.9 0.0 1.8 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_3 PF18428.1 EPS34591.1 - 0.00091 19.3 0.0 0.35 11.0 0.0 2.6 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain Corona_nucleoca PF00937.18 EPS34591.1 - 3.7 6.5 15.8 4.4 6.3 13.8 2.1 1 1 1 2 2 2 0 Coronavirus nucleocapsid protein Ribosomal_L27 PF01016.19 EPS34592.1 - 1.9e-27 95.1 0.0 3.4e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein Scramblase PF03803.15 EPS34594.1 - 6.5e-52 176.0 0.1 2.2e-27 95.8 0.0 3.0 2 1 0 2 2 2 2 Scramblase UQ_con PF00179.26 EPS34595.1 - 3e-49 166.3 0.0 3.3e-49 166.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TP6A_N PF04406.14 EPS34596.1 - 1.4e-20 73.0 0.2 2.5e-20 72.2 0.2 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase SQHop_cyclase_C PF13243.6 EPS34597.1 - 1.6e-49 168.7 1.2 1.2e-47 162.6 0.8 2.5 2 1 0 2 2 2 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 EPS34597.1 - 1.1e-44 152.7 2.8 2.8e-40 138.3 0.1 3.4 2 1 1 3 3 3 2 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 EPS34597.1 - 2e-32 110.6 1.9 4.2e-09 36.0 0.1 4.4 4 0 0 4 4 4 3 Prenyltransferase and squalene oxidase repeat Pec_lyase PF09492.10 EPS34597.1 - 9.8e-05 21.8 0.2 1.3 8.3 0.0 3.9 2 1 1 4 4 4 2 Pectic acid lyase TED_complement PF07678.14 EPS34597.1 - 0.0013 17.8 0.2 0.052 12.6 0.1 2.4 1 1 1 2 2 2 1 A-macroglobulin TED domain TSGP1 PF07771.11 EPS34597.1 - 0.095 12.9 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Tick salivary peptide group 1 SGS PF05002.15 EPS34598.1 - 2.8e-29 101.0 2.0 1e-28 99.2 2.0 2.0 1 0 0 1 1 1 1 SGS domain CS PF04969.16 EPS34598.1 - 2.1e-14 54.3 0.0 3.8e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 CS domain TPR_1 PF00515.28 EPS34598.1 - 0.014 15.2 0.2 2.5 8.1 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EPS34598.1 - 1 9.7 6.4 0.26 11.6 2.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat ThiJ_like PF17124.5 EPS34599.1 - 0.023 14.4 0.0 0.031 14.0 0.0 1.2 1 0 0 1 1 1 0 ThiJ/PfpI family-like GATase PF00117.28 EPS34599.1 - 0.038 13.7 0.0 0.051 13.3 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase class-I PQ-loop PF04193.14 EPS34600.1 - 2.1e-40 136.3 9.9 4.3e-21 74.5 1.6 2.7 2 0 0 2 2 2 2 PQ loop repeat tRNA-synt_1e PF01406.19 EPS34601.1 - 3.3e-115 384.6 0.0 5.5e-115 383.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EPS34601.1 - 1.8e-06 27.0 0.4 0.016 14.0 0.2 2.9 3 0 0 3 3 3 2 tRNA synthetases class I (M) DALR_2 PF09190.11 EPS34601.1 - 0.00074 19.9 1.2 0.0018 18.7 0.0 2.3 2 0 0 2 2 2 1 DALR domain tRNA-synt_1f PF01921.18 EPS34601.1 - 0.0074 15.2 0.0 0.045 12.7 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (K) GCD14 PF08704.10 EPS34602.1 - 8.9e-60 202.4 0.3 3.8e-59 200.3 0.0 2.2 2 1 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit UBA PF00627.31 EPS34603.1 - 1.1e-06 28.4 0.0 3.8e-06 26.7 0.0 2.0 1 0 0 1 1 1 1 UBA/TS-N domain TPR_2 PF07719.17 EPS34603.1 - 9.7e-05 22.2 2.1 0.065 13.4 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EPS34603.1 - 0.0079 16.0 0.7 1.8 8.5 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 EPS34603.1 - 0.024 14.8 0.2 0.18 12.0 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EPS34603.1 - 0.043 14.1 2.4 0.31 11.4 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EPS34603.1 - 0.079 13.5 1.5 11 6.6 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 EPS34603.1 - 0.081 13.6 6.5 1.6 9.4 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4203 PF13886.6 EPS34604.1 - 2.4e-47 161.2 26.2 3.3e-47 160.8 26.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) CHAT PF12770.7 EPS34606.1 - 1.8e-33 116.2 0.1 2.9e-33 115.5 0.1 1.3 1 0 0 1 1 1 1 CHAT domain Peptidase_C50 PF03568.17 EPS34606.1 - 0.0035 16.5 0.0 0.0092 15.1 0.0 1.6 1 1 0 1 1 1 1 Peptidase family C50 Ribonucleas_3_3 PF14622.6 EPS34607.1 - 1.9e-09 37.8 0.0 3e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EPS34607.1 - 4.4e-06 27.2 0.0 1.6e-05 25.5 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain Erf4 PF10256.9 EPS34608.1 - 4.9e-39 133.0 0.0 6.9e-39 132.5 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Adap_comp_sub PF00928.21 EPS34609.1 - 4.9e-85 285.1 0.0 5.9e-85 284.8 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family muHD PF10291.9 EPS34609.1 - 0.00044 19.8 0.2 0.00078 19.0 0.2 1.4 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Clat_adaptor_s PF01217.20 EPS34609.1 - 0.00086 19.3 0.1 0.0015 18.5 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain SOG2 PF10428.9 EPS34610.1 - 1.2 8.2 6.5 1.6 7.9 6.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Pkinase PF00069.25 EPS34611.1 - 9.1e-08 31.8 0.0 1.3e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.25 EPS34612.1 - 0.00031 20.2 0.1 0.00042 19.8 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS34612.1 - 0.077 12.3 0.1 0.096 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase FHA PF00498.26 EPS34613.1 - 8.7e-05 22.8 0.0 0.00017 21.9 0.0 1.5 2 0 0 2 2 2 1 FHA domain bVLRF1 PF18826.1 EPS34614.1 - 3.7e-62 208.6 0.2 7.6e-62 207.6 0.2 1.6 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank_5 PF13857.6 EPS34614.1 - 7.4e-06 26.1 0.0 1.7e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EPS34614.1 - 9.1e-05 22.7 0.6 0.00026 21.3 0.6 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 EPS34614.1 - 0.026 15.1 0.0 0.11 13.1 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EPS34614.1 - 0.038 14.5 0.0 0.13 12.9 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeat COX16 PF14138.6 EPS34614.1 - 7.4 7.2 6.1 9.8 6.8 0.5 3.3 3 0 0 3 3 3 0 Cytochrome c oxidase assembly protein COX16 ABC_membrane PF00664.23 EPS34615.1 - 1.4e-82 277.5 26.3 4e-46 157.9 8.7 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EPS34615.1 - 1.5e-52 177.7 0.0 1.4e-30 106.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EPS34615.1 - 1.7e-10 40.7 4.3 0.0027 17.2 0.2 4.1 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EPS34615.1 - 6.3e-06 26.3 0.4 0.2 11.7 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 EPS34615.1 - 6.4e-05 23.4 1.2 0.025 15.0 0.3 2.7 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EPS34615.1 - 0.00015 21.7 0.0 0.059 13.3 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EPS34615.1 - 0.00025 20.7 0.4 1.2 8.9 0.0 3.0 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.23 EPS34615.1 - 0.00028 21.0 0.7 0.035 14.2 0.0 2.7 2 0 0 2 2 2 1 Dynamin family DUF87 PF01935.17 EPS34615.1 - 0.001 19.2 0.4 1.2 9.2 0.0 2.8 2 0 0 2 2 2 2 Helicase HerA, central domain AAA_23 PF13476.6 EPS34615.1 - 0.002 18.7 0.0 0.23 11.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EPS34615.1 - 0.0073 16.1 1.1 0.53 10.0 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EPS34615.1 - 0.012 15.5 1.6 4 7.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EPS34615.1 - 0.032 13.9 0.7 1.5 8.5 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 EPS34615.1 - 0.044 14.1 1.7 7.6 6.8 0.0 3.4 2 1 0 2 2 2 0 AAA domain AIG1 PF04548.16 EPS34615.1 - 0.26 10.6 1.4 5.2 6.3 0.0 2.6 2 0 0 2 2 2 0 AIG1 family Roc PF08477.13 EPS34615.1 - 0.5 10.6 3.7 34 4.7 0.1 3.7 4 0 0 4 4 3 0 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 EPS34615.1 - 0.54 10.2 4.5 2.6 8.0 0.1 3.0 3 0 0 3 3 3 0 NACHT domain Curto_V3 PF07436.11 EPS34615.1 - 0.57 10.6 3.1 2.7 8.5 0.0 2.9 2 0 0 2 2 2 0 Curtovirus V3 protein DUF2841 PF11001.8 EPS34617.1 - 1e-42 145.1 0.1 1.5e-42 144.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) EIN3 PF04873.13 EPS34617.1 - 0.00095 18.5 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 Ethylene insensitive 3 SAC3_GANP PF03399.16 EPS34618.1 - 7.9e-101 337.3 4.5 1.1e-100 336.9 4.5 1.2 1 0 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 EPS34618.1 - 4.9e-05 23.3 0.5 0.00022 21.2 0.3 2.1 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family ssDNA-exonuc_C PF10141.9 EPS34618.1 - 0.042 13.5 0.1 0.1 12.2 0.1 1.6 1 0 0 1 1 1 0 Single-strand DNA-specific exonuclease, C terminal domain ACPS PF01648.20 EPS34618.1 - 7.2 6.8 6.8 51 4.0 6.8 2.3 1 1 0 1 1 1 0 4'-phosphopantetheinyl transferase superfamily CN_hydrolase PF00795.22 EPS34619.1 - 3.3e-14 52.8 0.0 5.2e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase HLH PF00010.26 EPS34621.1 - 1.9e-13 50.1 2.1 3.9e-13 49.1 2.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DPBB_1 PF03330.18 EPS34622.1 - 7.4e-08 32.6 0.3 3.2e-07 30.5 0.0 2.4 2 1 0 2 2 2 1 Lytic transglycolase Pollen_allerg_1 PF01357.21 EPS34622.1 - 2e-05 24.5 0.7 7.1e-05 22.8 0.4 2.1 2 0 0 2 2 2 1 Pollen allergen SPX PF03105.19 EPS34622.1 - 0.017 15.0 1.3 0.016 15.1 1.3 1.1 1 0 0 1 1 1 0 SPX domain InPase PF18823.1 EPS34622.1 - 0.067 12.9 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Inorganic Pyrophosphatase Apt1 PF10351.9 EPS34622.1 - 0.18 10.6 2.5 0.22 10.3 2.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.9 EPS34622.1 - 0.76 8.3 6.9 0.95 7.9 6.9 1.1 1 0 0 1 1 1 0 Macoilin family Sec8_exocyst PF04048.14 EPS34623.1 - 6.8e-47 158.9 1.0 1.7e-46 157.6 1.0 1.8 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 EPS34623.1 - 2.5e-07 30.3 0.3 4.8e-07 29.4 0.3 1.4 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Dor1 PF04124.12 EPS34623.1 - 0.00022 20.0 2.5 0.00046 19.0 2.5 1.5 1 0 0 1 1 1 1 Dor1-like family Zw10 PF06248.13 EPS34623.1 - 0.0032 16.1 0.3 0.0081 14.8 0.3 1.6 1 0 0 1 1 1 1 Centromere/kinetochore Zw10 Sec5 PF15469.6 EPS34623.1 - 0.015 15.1 0.5 0.031 14.1 0.5 1.5 1 0 0 1 1 1 0 Exocyst complex component Sec5 TPP_enzyme_N PF02776.18 EPS34623.1 - 0.055 13.1 0.1 0.2 11.3 0.0 1.9 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain ParD_antitoxin PF03693.14 EPS34623.1 - 0.13 12.7 0.1 0.46 10.9 0.1 1.9 1 0 0 1 1 1 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH BCS1_N PF08740.11 EPS34623.1 - 0.32 11.0 2.5 0.66 9.9 0.0 2.3 2 0 0 2 2 2 0 BCS1 N terminal Creatinase_N_2 PF16189.5 EPS34624.1 - 7e-54 182.3 0.1 9.3e-53 178.6 0.0 2.2 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 EPS34624.1 - 3e-41 141.4 0.0 4.1e-41 141.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 EPS34624.1 - 6.3e-24 83.8 0.7 1.9e-23 82.3 0.7 1.9 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 EPS34624.1 - 1.1e-17 64.9 0.1 5.5e-16 59.4 0.0 2.9 3 1 0 3 3 3 1 Creatinase/Prolidase N-terminal domain MUG113 PF13455.6 EPS34625.1 - 6.2e-29 100.5 0.1 1.3e-28 99.5 0.1 1.5 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.9 EPS34625.1 - 1.1e-26 93.3 0.0 2.8e-26 92.1 0.0 1.7 1 0 0 1 1 1 1 T5orf172 domain SnoaL PF07366.12 EPS34626.1 - 0.0011 18.8 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 EPS34626.1 - 0.0017 19.0 0.1 0.0032 18.1 0.1 1.4 1 0 0 1 1 1 1 SnoaL-like domain SOR_SNZ PF01680.17 EPS34629.1 - 3e-108 360.3 5.9 3e-108 360.3 5.9 1.4 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.14 EPS34629.1 - 3e-09 36.6 8.6 1.1e-06 28.1 0.3 2.5 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 EPS34629.1 - 0.00094 18.4 1.4 0.32 10.1 0.0 2.6 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) IGPS PF00218.21 EPS34629.1 - 0.0048 16.1 0.1 0.43 9.7 0.0 2.5 2 1 0 2 2 2 2 Indole-3-glycerol phosphate synthase NanE PF04131.14 EPS34629.1 - 0.0067 15.6 0.9 0.19 10.9 0.0 2.5 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.21 EPS34629.1 - 0.011 15.2 0.8 0.33 10.4 0.0 2.7 2 2 1 3 3 3 0 Histidine biosynthesis protein NMO PF03060.15 EPS34629.1 - 0.024 14.0 7.0 0.048 13.0 0.5 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase SecY PF00344.20 EPS34630.1 - 2.5e-73 247.0 6.7 3.2e-73 246.7 6.7 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 EPS34630.1 - 2.5e-17 62.4 0.3 6e-17 61.2 0.3 1.7 1 0 0 1 1 1 1 Plug domain of Sec61p MARVEL PF01284.23 EPS34630.1 - 0.41 10.7 0.1 0.41 10.7 0.1 3.2 2 1 0 2 2 2 0 Membrane-associating domain Phage_GPO PF05929.11 EPS34631.1 - 0.0096 15.6 5.2 0.014 15.0 5.2 1.2 1 0 0 1 1 1 1 Phage capsid scaffolding protein (GPO) serine peptidase Phage_GP20 PF06810.11 EPS34631.1 - 0.013 15.3 5.1 0.022 14.5 5.1 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 TMCO5 PF14992.6 EPS34631.1 - 0.057 13.0 4.3 0.077 12.6 4.3 1.1 1 0 0 1 1 1 0 TMCO5 family BAF1_ABF1 PF04684.13 EPS34631.1 - 0.066 12.3 6.4 0.094 11.8 6.4 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Exonuc_VII_L PF02601.15 EPS34631.1 - 0.072 12.7 5.0 0.095 12.2 5.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit HAUS5 PF14817.6 EPS34631.1 - 0.13 11.0 7.1 0.19 10.5 7.1 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 DUF2570 PF10828.8 EPS34631.1 - 0.13 12.1 1.3 0.27 11.1 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) BLOC1_2 PF10046.9 EPS34631.1 - 0.16 12.3 3.3 0.3 11.4 3.3 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tweety PF04906.13 EPS34631.1 - 0.27 9.9 1.5 0.39 9.3 1.5 1.1 1 0 0 1 1 1 0 Tweety DUF4407 PF14362.6 EPS34631.1 - 0.55 9.5 5.8 0.79 9.0 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CALCOCO1 PF07888.11 EPS34631.1 - 1.3 7.8 16.5 0.029 13.3 10.2 1.4 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Cyclin_N PF00134.23 EPS34632.1 - 0.00053 19.7 0.0 0.0018 18.0 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 EPS34632.1 - 0.0012 18.8 0.0 0.32 11.1 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Autophagy_N PF03986.13 EPS34633.1 - 4.8e-46 156.1 0.0 9.7e-46 155.1 0.0 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_C PF10381.9 EPS34633.1 - 3.7e-15 55.1 0.2 6.3e-15 54.4 0.2 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Autophagy_act_C PF03987.15 EPS34633.1 - 5.7e-13 49.2 0.2 1.1e-12 48.3 0.2 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain CBM_2 PF00553.19 EPS34634.1 - 0.099 13.0 0.7 2.6 8.4 0.1 2.5 1 1 1 2 2 2 0 Cellulose binding domain ArgJ PF01960.18 EPS34637.1 - 3.2e-151 503.3 0.3 3.7e-151 503.1 0.3 1.0 1 0 0 1 1 1 1 ArgJ family ORC2 PF04084.14 EPS34638.1 - 1.2e-118 395.9 0.0 1.6e-118 395.4 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 2 FliH PF02108.16 EPS34638.1 - 0.003 17.6 0.0 0.0059 16.7 0.0 1.4 1 0 0 1 1 1 1 Flagellar assembly protein FliH ORC6 PF05460.13 EPS34638.1 - 0.75 9.0 12.3 1.1 8.4 12.3 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) FUN14 PF04930.15 EPS34639.1 - 7.1e-09 36.0 0.4 1.3e-08 35.2 0.4 1.4 1 0 0 1 1 1 1 FUN14 family DUF543 PF04418.12 EPS34639.1 - 0.06 13.3 1.1 2.6 8.1 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF543) Glycos_transf_2 PF00535.26 EPS34640.1 - 7.4e-23 81.2 0.0 2.1e-21 76.5 0.0 2.6 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EPS34640.1 - 1.5e-06 28.3 0.0 0.0033 17.3 0.0 2.7 3 0 0 3 3 3 2 Glycosyltransferase like family 2 EST1_DNA_bind PF10373.9 EPS34641.1 - 3.4e-05 23.5 0.7 0.00012 21.6 0.7 2.0 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain NUDIX PF00293.28 EPS34643.1 - 1e-07 32.1 0.0 2e-07 31.1 0.0 1.4 1 1 0 1 1 1 1 NUDIX domain NUDIX PF00293.28 EPS34644.1 - 4.9e-17 62.2 0.0 7.4e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain HAD_2 PF13419.6 EPS34645.1 - 7.3e-21 75.1 0.1 9.3e-21 74.7 0.1 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EPS34645.1 - 1e-06 29.2 1.1 7e-06 26.5 1.1 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EPS34645.1 - 2.9e-05 24.0 0.0 5.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 EPS34645.1 - 0.00011 22.6 0.0 0.00014 22.3 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGA_cap PF09587.10 EPS34645.1 - 0.17 11.3 0.0 0.46 9.9 0.0 1.5 1 1 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap Rit1_C PF17184.4 EPS34646.1 - 1.2e-102 343.1 0.0 1.6e-102 342.6 0.0 1.2 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 EPS34646.1 - 5.6e-34 116.8 0.1 2e-33 115.0 0.0 2.0 2 0 0 2 2 2 1 Rit1 DUSP-like domain YfhD PF14151.6 EPS34646.1 - 0.034 14.3 0.0 0.084 13.0 0.0 1.6 1 0 0 1 1 1 0 YfhD-like protein Aldo_ket_red PF00248.21 EPS34647.1 - 1e-45 156.2 0.0 2.5e-43 148.4 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family NMT1_2 PF13379.6 EPS34647.1 - 0.011 15.4 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 NMT1-like family BLACT_WH PF17778.1 EPS34647.1 - 0.088 12.8 0.1 0.41 10.7 0.0 2.0 2 0 0 2 2 2 0 Beta-lactamase associated winged helix domain ALMT PF11744.8 EPS34647.1 - 0.14 11.0 0.1 0.19 10.5 0.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter CH PF00307.31 EPS34648.1 - 8.6e-46 154.6 0.1 2.7e-22 79.0 0.0 3.1 3 0 0 3 3 3 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.10 EPS34648.1 - 1.1e-27 95.9 0.0 3.7e-27 94.2 0.0 2.0 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.8 EPS34648.1 - 6.3e-10 38.8 0.3 1.4e-05 24.8 0.0 3.0 2 0 0 2 2 2 2 CAMSAP CH domain EF-hand_6 PF13405.6 EPS34648.1 - 0.00028 20.6 0.0 0.0017 18.2 0.0 2.4 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 EPS34648.1 - 0.0021 17.4 0.1 0.024 14.2 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 EPS34648.1 - 0.017 15.0 0.2 0.11 12.4 0.0 2.5 3 0 0 3 3 3 0 EF-hand domain pair Spectrin PF00435.21 EPS34648.1 - 0.023 15.2 7.9 0.29 11.6 0.0 3.5 3 0 0 3 3 3 0 Spectrin repeat FliG_N PF14842.6 EPS34648.1 - 0.049 14.2 0.9 3.5 8.2 0.1 3.0 2 1 1 3 3 3 0 FliG N-terminal domain Phage_int_SAM_2 PF12834.7 EPS34648.1 - 0.086 13.5 0.0 0.28 11.9 0.0 1.9 1 0 0 1 1 1 0 Phage integrase, N-terminal EF-hand_7 PF13499.6 EPS34648.1 - 0.13 12.8 4.6 0.36 11.3 0.1 3.7 4 0 0 4 4 4 0 EF-hand domain pair RRM_1 PF00076.22 EPS34649.1 - 3.8e-15 55.4 0.0 5.9e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 EPS34649.1 - 4.4e-08 33.6 15.7 4.4e-08 33.6 15.7 4.3 3 1 1 4 4 4 3 C-terminal duplication domain of Friend of PRMT1 WD40 PF00400.32 EPS34650.1 - 1.6e-22 79.4 12.1 3.3e-07 30.9 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS34650.1 - 8.2e-09 35.7 0.1 0.17 12.2 0.0 5.0 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EPS34650.1 - 0.0013 17.8 0.7 0.17 10.8 0.0 2.5 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Me-amine-dh_H PF06433.11 EPS34650.1 - 0.0053 15.7 0.0 1.6 7.5 0.0 2.2 2 0 0 2 2 2 2 Methylamine dehydrogenase heavy chain (MADH) Cytochrom_D1 PF02239.16 EPS34650.1 - 0.012 14.2 0.0 0.02 13.4 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain Nup160 PF11715.8 EPS34650.1 - 0.22 10.1 0.1 4.8 5.7 0.0 2.2 2 0 0 2 2 2 0 Nucleoporin Nup120/160 PUL PF08324.11 EPS34651.1 - 7.3e-71 238.6 1.9 1.1e-70 238.1 1.9 1.3 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 EPS34651.1 - 1.3e-44 151.1 0.1 2.2e-44 150.3 0.1 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 EPS34651.1 - 2e-32 110.7 10.3 6.1e-07 30.0 0.0 8.0 8 0 0 8 8 8 5 WD domain, G-beta repeat BBS2_Mid PF14783.6 EPS34651.1 - 0.0051 16.8 0.0 0.57 10.3 0.0 3.4 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region ADH_N PF08240.12 EPS34652.1 - 9.6e-29 99.5 2.1 2.7e-28 98.0 1.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPS34652.1 - 2.4e-15 56.6 0.0 3.9e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 EPS34652.1 - 0.00012 21.6 0.3 0.00042 19.8 0.3 1.8 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 EPS34652.1 - 0.00044 21.3 0.2 0.0013 19.8 0.2 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EPS34652.1 - 0.035 13.4 0.4 0.074 12.3 0.4 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EPS34652.1 - 0.12 11.7 0.1 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain YjeF_N PF03853.15 EPS34653.1 - 1.2e-37 129.4 0.0 1.5e-37 129.1 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Ribosomal_S16 PF00886.19 EPS34654.1 - 9.6e-25 86.4 0.2 1.5e-24 85.8 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 RRM_1 PF00076.22 EPS34656.1 - 8.1e-16 57.6 0.1 8e-13 48.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EPS34656.1 - 0.24 11.3 0.0 0.39 10.6 0.0 1.3 1 0 0 1 1 1 0 Occluded RNA-recognition motif Prolamin_like PF05617.11 EPS34658.1 - 0.024 14.8 0.4 0.036 14.3 0.4 1.3 1 0 0 1 1 1 0 Prolamin-like Bot1p PF12298.8 EPS34659.1 - 2.7e-50 170.9 0.1 2.7e-50 170.9 0.1 2.1 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein HAMP_N3 PF18575.1 EPS34659.1 - 0.16 11.6 0.0 0.35 10.5 0.0 1.6 1 0 0 1 1 1 0 HAMP N-terminal domain 3 HNH_2 PF13391.6 EPS34663.1 - 3.1e-06 27.2 0.1 8.6e-06 25.8 0.0 1.8 2 0 0 2 2 2 1 HNH endonuclease Sugar_tr PF00083.24 EPS34664.1 - 3.6e-85 286.5 18.3 4.4e-85 286.2 18.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS34664.1 - 9.2e-20 70.9 29.4 9.2e-20 70.9 29.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 EPS34664.1 - 0.00018 20.2 3.0 0.00018 20.2 3.0 2.5 2 1 0 2 2 2 1 MFS/sugar transport protein TRI12 PF06609.13 EPS34664.1 - 0.00024 19.7 1.1 0.00041 18.9 1.1 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 EPS34664.1 - 0.0017 16.7 5.0 0.002 16.5 0.2 2.2 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family DUF2530 PF10745.9 EPS34664.1 - 0.87 9.9 7.3 1.6 9.0 4.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Response_reg PF00072.24 EPS34666.1 - 2.1e-19 69.7 0.0 5.3e-13 49.1 0.0 2.2 2 0 0 2 2 2 2 Response regulator receiver domain PQ-loop PF04193.14 EPS34667.1 - 5.6e-20 70.9 13.5 2.7e-19 68.7 0.8 3.2 3 1 1 4 4 4 2 PQ loop repeat ABC2_membrane_5 PF13346.6 EPS34667.1 - 0.013 15.1 7.7 0.16 11.5 4.5 2.3 2 0 0 2 2 2 0 ABC-2 family transporter protein SH3_1 PF00018.28 EPS34668.1 - 5.1e-09 35.6 0.0 1e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EPS34668.1 - 2.1e-06 27.3 0.0 6.4e-06 25.8 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 EPS34668.1 - 3.9e-06 26.6 0.0 7.3e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_10 PF17902.1 EPS34668.1 - 0.1 12.7 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 SH3 domain Dynactin_p22 PF07426.11 EPS34669.1 - 1.3e-08 34.9 0.0 2e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Dynactin subunit p22 UBA_4 PF14555.6 EPS34670.1 - 1.9e-11 43.6 0.8 6.2e-11 41.9 0.4 2.1 2 0 0 2 2 2 1 UBA-like domain Dscam_C PF12355.8 EPS34670.1 - 0.0083 17.1 1.8 0.0083 17.1 1.8 2.1 2 0 0 2 2 2 1 Down syndrome cell adhesion molecule C terminal UIM PF02809.20 EPS34670.1 - 0.016 15.1 0.6 0.038 13.9 0.6 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif VPS38 PF17649.1 EPS34670.1 - 0.38 9.6 1.1 0.62 8.9 1.1 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting 38 SET PF00856.28 EPS34671.1 - 3.5e-15 56.8 0.4 1.6e-13 51.4 0.4 2.3 1 1 0 1 1 1 1 SET domain Gtr1_RagA PF04670.12 EPS34672.1 - 1.5e-94 315.8 0.2 1.7e-94 315.5 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Roc PF08477.13 EPS34672.1 - 1.2e-08 35.2 0.0 2.2e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPS34672.1 - 3.8e-08 33.0 0.0 5.8e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EPS34672.1 - 4.6e-08 32.8 0.0 7.1e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 EPS34672.1 - 2.4e-07 30.9 0.0 4.5e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 EPS34672.1 - 0.001 19.1 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain GTP_EFTU PF00009.27 EPS34672.1 - 0.0017 17.9 0.0 0.0028 17.2 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 EPS34672.1 - 0.0027 16.9 4.2 0.41 9.7 0.0 2.5 2 1 1 3 3 3 2 G-protein alpha subunit DUF815 PF05673.13 EPS34672.1 - 0.0095 15.1 0.1 0.019 14.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_29 PF13555.6 EPS34672.1 - 0.011 15.4 0.4 0.058 13.1 0.2 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EPS34672.1 - 0.017 15.6 0.0 0.036 14.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter RsgA_GTPase PF03193.16 EPS34672.1 - 0.047 13.6 0.2 0.37 10.7 0.0 2.4 3 0 0 3 3 3 0 RsgA GTPase AAA_7 PF12775.7 EPS34672.1 - 0.12 11.9 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AIG1 PF04548.16 EPS34672.1 - 0.16 11.3 0.2 0.48 9.7 0.0 1.9 2 0 0 2 2 2 0 AIG1 family DUF1688 PF07958.11 EPS34673.1 - 2.6e-182 606.3 0.0 2.9e-182 606.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) DDT PF02791.17 EPS34673.1 - 0.01 16.1 0.1 3.5 8.0 0.1 2.6 1 1 1 2 2 2 0 DDT domain SSB PF00436.25 EPS34676.1 - 3.1e-17 62.5 0.0 4e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family STE3 PF02076.15 EPS34677.1 - 3e-87 292.5 16.6 3.6e-87 292.2 16.6 1.1 1 0 0 1 1 1 1 Pheromone A receptor DUF3671 PF12420.8 EPS34677.1 - 1.1 9.3 3.9 0.56 10.3 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF1993 PF09351.10 EPS34678.1 - 0.28 11.3 2.5 5.3 7.2 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1993) DUF3431 PF11913.8 EPS34679.1 - 7.4e-85 284.1 2.8 9.2e-85 283.8 2.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Ku PF02735.16 EPS34680.1 - 1.1e-45 155.9 0.0 2.6e-45 154.6 0.0 1.6 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 EPS34680.1 - 1.7e-30 106.4 0.0 2.8e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 EPS34680.1 - 1.1e-25 90.1 0.1 2.4e-25 89.1 0.1 1.6 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.27 EPS34680.1 - 1.5e-05 24.6 0.0 3e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 SAP domain Ish1 PF10281.9 EPS34680.1 - 0.018 15.3 0.0 0.048 14.0 0.0 1.7 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein Ferrochelatase PF00762.19 EPS34681.1 - 1.8e-98 329.5 0.0 2.1e-98 329.3 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase MFS_1 PF07690.16 EPS34682.1 - 4.8e-29 101.4 27.6 8.2e-25 87.5 14.7 2.7 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS34682.1 - 0.00013 20.9 16.2 0.00014 20.8 11.5 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter DUF1751 PF08551.10 EPS34682.1 - 0.019 15.5 1.9 0.07 13.7 0.7 2.5 2 0 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) PPR PF01535.20 EPS34683.1 - 1.9e-07 30.9 1.5 0.22 11.9 0.0 4.6 5 0 0 5 5 5 3 PPR repeat PPR_2 PF13041.6 EPS34683.1 - 8.1e-05 22.7 0.1 0.17 12.1 0.0 3.8 3 0 0 3 3 3 2 PPR repeat family USP8_interact PF08941.10 EPS34683.1 - 0.019 14.8 0.3 0.063 13.1 0.0 2.0 2 0 0 2 2 2 0 USP8 interacting TPR_19 PF14559.6 EPS34683.1 - 0.02 15.4 0.0 3.6 8.2 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat PPR_long PF17177.4 EPS34683.1 - 0.039 13.3 0.0 0.11 11.8 0.0 1.7 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP TPR_2 PF07719.17 EPS34683.1 - 0.19 11.9 1.3 0.95 9.7 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat adh_short PF00106.25 EPS34684.1 - 2.3e-30 105.5 0.0 2.9e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS34684.1 - 3.4e-22 79.2 0.0 4e-22 78.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPS34684.1 - 1.8e-07 31.2 0.0 2.6e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EPS34684.1 - 9e-05 22.4 0.1 0.00025 21.0 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 EPS34684.1 - 0.0028 17.1 0.1 0.02 14.3 0.1 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EPS34684.1 - 0.013 15.1 0.1 0.026 14.1 0.1 1.5 1 0 0 1 1 1 0 NmrA-like family Raftlin PF15250.6 EPS34684.1 - 0.08 11.7 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Raftlin SE PF08491.10 EPS34685.1 - 1.6e-96 322.6 0.0 2.1e-96 322.2 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 EPS34685.1 - 5.9e-09 35.6 0.9 9e-06 25.2 0.2 2.4 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.24 EPS34685.1 - 1.2e-06 28.4 0.1 2.9e-05 23.8 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EPS34685.1 - 0.00071 19.8 0.5 0.0014 18.8 0.5 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.7 EPS34685.1 - 0.0014 18.0 0.3 0.002 17.5 0.3 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EPS34685.1 - 0.0034 16.5 0.7 0.0057 15.8 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EPS34685.1 - 0.004 16.4 0.0 0.013 14.8 0.0 1.7 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 EPS34685.1 - 0.0072 15.4 0.3 0.014 14.5 0.3 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.14 EPS34685.1 - 0.0078 15.1 0.5 0.55 9.0 0.1 2.4 2 1 0 2 2 2 1 Tryptophan halogenase GIDA PF01134.22 EPS34685.1 - 0.0082 15.3 0.0 0.053 12.6 0.1 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 EPS34685.1 - 0.011 14.9 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EPS34685.1 - 0.014 15.9 0.2 0.027 15.0 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 EPS34685.1 - 0.022 14.4 0.1 0.035 13.8 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.21 EPS34685.1 - 0.091 12.1 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 ThiF family HI0933_like PF03486.14 EPS34685.1 - 0.13 10.9 0.2 0.26 10.0 0.2 1.4 1 0 0 1 1 1 0 HI0933-like protein NAD_Gly3P_dh_N PF01210.23 EPS34685.1 - 0.15 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Tox-GHH2 PF15635.6 EPS34686.1 - 0.0075 16.8 0.0 0.0081 16.7 0.0 1.1 1 0 0 1 1 1 1 GHH signature containing HNH/Endo VII superfamily nuclease toxin 2 PAP_assoc PF03828.19 EPS34687.1 - 1.9e-17 63.2 0.1 4.1e-17 62.1 0.1 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EPS34687.1 - 0.00019 21.6 0.0 0.00042 20.5 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EPS34687.1 - 0.013 15.6 0.0 0.027 14.6 0.0 1.5 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase CALM_bind PF16025.5 EPS34688.1 - 0.13 12.7 6.0 0.24 11.9 6.0 1.4 1 0 0 1 1 1 0 Calcium-dependent calmodulin binding SLC35F PF06027.12 EPS34689.1 - 2.6e-100 335.8 23.0 3.1e-100 335.6 23.0 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 EPS34689.1 - 4.8e-09 35.6 4.0 7.9e-09 34.9 4.0 1.3 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 EPS34689.1 - 7.9e-08 32.6 29.0 0.00031 20.9 7.5 2.2 2 0 0 2 2 2 2 EamA-like transporter family SMK-1 PF04802.15 EPS34690.1 - 1.7e-79 266.1 0.5 3.1e-79 265.3 0.5 1.5 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 LIDHydrolase PF10230.9 EPS34691.1 - 1.5e-80 270.6 0.0 1.9e-80 270.3 0.0 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 EPS34691.1 - 2.4e-05 25.1 0.1 3.3e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPS34691.1 - 0.0024 17.2 0.1 0.012 14.8 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EPS34691.1 - 0.012 15.3 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF726 PF05277.12 EPS34691.1 - 0.036 13.0 0.1 0.055 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Thioesterase PF00975.20 EPS34691.1 - 0.061 13.4 0.0 0.15 12.2 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain Abhydrolase_3 PF07859.13 EPS34691.1 - 0.069 13.0 0.0 0.23 11.3 0.0 1.7 1 1 0 2 2 2 0 alpha/beta hydrolase fold PGAP1 PF07819.13 EPS34691.1 - 0.18 11.5 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein DCP1 PF06058.13 EPS34692.1 - 7.4e-29 100.1 0.0 1.2e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 Dcp1-like decapping family DUF2076 PF09849.9 EPS34692.1 - 1.6 8.7 23.7 0.07 13.2 11.9 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) Exo_endo_phos PF03372.23 EPS34693.1 - 1.8e-07 30.9 0.0 4e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCCH PF00642.24 EPS34694.1 - 7.9e-09 35.2 0.6 1.4e-08 34.4 0.6 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 EPS34694.1 - 2.3e-07 30.6 7.0 4.2e-07 29.7 7.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EPS34694.1 - 4.6e-07 29.6 8.5 7.9e-07 28.8 8.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EPS34694.1 - 5.1e-07 29.6 9.1 8.2e-07 28.9 9.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EPS34694.1 - 5.1e-07 29.6 7.0 9.9e-07 28.7 7.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EPS34694.1 - 2.2e-06 27.4 10.8 3.7e-06 26.7 10.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 EPS34694.1 - 2.9e-06 27.3 2.8 5.7e-06 26.4 2.8 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf_CCCH_4 PF18345.1 EPS34694.1 - 5.1e-06 26.4 4.9 1.2e-05 25.2 4.9 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-RING_2 PF13639.6 EPS34694.1 - 1.2e-05 25.5 7.7 2.2e-05 24.7 7.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-CCCH_4 PF18044.1 EPS34694.1 - 0.00038 20.2 0.7 0.00038 20.2 0.7 2.1 2 0 0 2 2 1 1 CCCH-type zinc finger Prok-RING_4 PF14447.6 EPS34694.1 - 0.0016 18.2 6.7 0.003 17.4 6.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EPS34694.1 - 0.0036 17.4 9.1 0.0069 16.5 9.1 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-CCCH_2 PF14608.6 EPS34694.1 - 0.021 15.3 0.9 0.021 15.3 0.9 1.8 2 0 0 2 2 1 0 RNA-binding, Nab2-type zinc finger zf-Nse PF11789.8 EPS34694.1 - 0.12 12.2 2.0 0.21 11.4 2.0 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 EPS34694.1 - 0.27 11.5 4.5 0.61 10.4 4.5 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain Uso1_p115_C PF04871.13 EPS34694.1 - 0.74 10.2 12.1 0.14 12.5 3.6 2.4 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region Mcp5_PH PF12814.7 EPS34696.1 - 1.4e-45 154.3 0.3 2.5e-45 153.5 0.3 1.4 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 EPS34696.1 - 1.2e-06 29.0 0.0 2.6e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 PH domain Ribosomal_L12_N PF16320.5 EPS34696.1 - 4.4 7.1 0.0 4.4 7.1 0.0 3.4 3 0 0 3 3 3 0 Ribosomal protein L7/L12 dimerisation domain DUF3584 PF12128.8 EPS34696.1 - 7.3 4.0 45.5 0.42 8.1 32.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Methyltransf_23 PF13489.6 EPS34697.1 - 6.2e-14 52.2 0.0 8.9e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS34697.1 - 1.1e-08 35.6 0.0 5.3e-08 33.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPS34697.1 - 1.6e-06 28.8 0.0 9.4e-06 26.3 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EPS34697.1 - 6.4e-06 26.0 0.0 0.00017 21.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPS34697.1 - 1.7e-05 25.4 0.0 0.00044 20.9 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain DUF2439 PF10382.9 EPS34698.1 - 4e-28 97.6 0.4 6.4e-28 96.9 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) EFTUD2 PF16004.5 EPS34698.1 - 0.12 13.0 0.2 0.12 13.0 0.2 2.0 3 0 0 3 3 3 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus SH3_9 PF14604.6 EPS34699.1 - 4.8e-16 58.3 0.1 1.1e-15 57.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EPS34699.1 - 4e-12 45.5 0.1 6.8e-12 44.8 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EPS34699.1 - 7.1e-12 44.8 0.0 1.2e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain BAR PF03114.18 EPS34699.1 - 7e-10 39.0 2.0 1e-09 38.4 2.0 1.2 1 0 0 1 1 1 1 BAR domain DUF4407 PF14362.6 EPS34699.1 - 0.065 12.6 0.5 0.098 12.0 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V-SNARE PF05008.15 EPS34699.1 - 0.098 13.1 3.2 4.1 7.9 0.7 3.0 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus INCENP_ARK-bind PF03941.15 EPS34700.1 - 0.0045 16.9 0.2 0.023 14.6 0.0 2.2 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region Polysacc_deac_3 PF15421.6 EPS34700.1 - 0.13 10.7 0.0 0.21 10.1 0.0 1.2 1 0 0 1 1 1 0 Putative polysaccharide deacetylase RTC PF01137.21 EPS34701.1 - 9e-47 159.1 0.0 1.5e-46 158.4 0.0 1.3 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase PriC PF07445.12 EPS34704.1 - 3.6 7.5 5.3 8.2 6.3 1.3 2.2 2 0 0 2 2 2 0 Primosomal replication protein priC CPSase_L_D2 PF02786.17 EPS34706.1 - 1.6e-56 191.1 0.0 3e-56 190.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 EPS34706.1 - 2.7e-32 111.1 0.0 6.7e-32 109.8 0.0 1.7 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 EPS34706.1 - 1.7e-28 99.3 0.0 3.6e-28 98.3 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Dala_Dala_lig_C PF07478.13 EPS34706.1 - 2e-11 43.8 0.0 4.2e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl PF00364.22 EPS34706.1 - 3.5e-10 39.6 0.4 1.1e-09 38.0 0.4 1.9 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.22 EPS34706.1 - 3.9e-08 33.1 0.1 6.8e-08 32.3 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EPS34706.1 - 1.5e-05 25.1 0.0 2.6e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.11 EPS34706.1 - 6.1e-05 22.7 0.3 0.0031 17.1 0.0 2.8 2 1 0 2 2 2 1 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.6 EPS34706.1 - 0.0004 19.7 0.0 0.00071 18.9 0.0 1.3 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp RnfC_N PF13375.6 EPS34706.1 - 0.0018 18.2 0.0 0.0064 16.4 0.0 2.0 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl_2 PF13533.6 EPS34706.1 - 0.0022 17.8 0.1 0.0057 16.5 0.1 1.6 1 0 0 1 1 1 1 Biotin-lipoyl like ATP-grasp_2 PF08442.10 EPS34706.1 - 0.021 14.4 0.3 0.11 12.0 0.0 2.1 2 0 0 2 2 2 0 ATP-grasp domain GSH-S_ATP PF02955.16 EPS34706.1 - 0.029 13.8 0.0 0.064 12.7 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain ATPgrasp_Ter PF15632.6 EPS34706.1 - 0.029 14.1 0.0 0.06 13.1 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon BBP2 PF07642.11 EPS34706.1 - 0.13 11.4 0.1 0.19 10.8 0.1 1.2 1 0 0 1 1 1 0 Putative beta-barrel porin-2, OmpL-like. bbp2 ATPgrasp_YheCD PF14398.6 EPS34706.1 - 0.15 11.3 0.0 0.4 9.9 0.0 1.6 2 0 0 2 2 2 0 YheC/D like ATP-grasp Carboxyl_trans PF01039.22 EPS34707.1 - 3e-82 276.8 0.0 4.1e-82 276.4 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain S-methyl_trans PF02574.16 EPS34708.1 - 6.5e-62 209.8 0.0 7.4e-62 209.6 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase AA_permease PF00324.21 EPS34709.1 - 2.3e-118 395.8 41.5 2.8e-118 395.5 41.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EPS34709.1 - 9.6e-40 136.7 46.2 1.2e-39 136.4 45.5 1.4 1 1 1 2 2 2 1 Amino acid permease ArAE_2_N PF10337.9 EPS34710.1 - 5e-118 395.1 0.0 1.3e-116 390.5 0.0 2.1 2 0 0 2 2 2 2 Putative ER transporter, 6TM, N-terminal ArAE_2 PF10334.9 EPS34710.1 - 1e-61 208.7 0.0 1.5e-60 204.9 0.0 2.3 2 0 0 2 2 2 1 Aromatic acid exporter family member 2 FUSC_2 PF13515.6 EPS34710.1 - 1.1e-07 32.0 15.9 1.1e-07 32.0 15.9 3.3 3 1 0 3 3 3 1 Fusaric acid resistance protein-like HPP PF04982.13 EPS34711.1 - 2.4e-42 143.9 3.4 2.4e-42 143.9 3.4 1.8 2 0 0 2 2 2 1 HPP family Pkinase PF00069.25 EPS34713.1 - 2.7e-18 66.3 0.0 1.1e-09 38.1 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EPS34713.1 - 6.8e-06 25.5 2.4 0.0011 18.3 0.0 3.0 3 1 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 EPS34713.1 - 0.00017 21.0 0.5 0.2 11.0 0.1 2.2 2 0 0 2 2 2 2 Kinase-like RNA_capsid PF03035.14 EPS34714.1 - 0.037 14.0 0.1 0.061 13.3 0.1 1.5 1 1 0 1 1 1 0 Calicivirus putative RNA polymerase/capsid protein CAP59_mtransfer PF11735.8 EPS34715.1 - 4.5e-87 291.7 0.0 8.1e-87 290.9 0.0 1.4 1 1 0 1 1 1 1 Cryptococcal mannosyltransferase 1 NADH_Oxid_Nqo15 PF11497.8 EPS34715.1 - 0.11 12.6 0.1 0.27 11.3 0.1 1.6 1 0 0 1 1 1 0 NADH-quinone oxidoreductase chain 15 DUF1772 PF08592.11 EPS34716.1 - 8e-05 23.0 0.1 0.00012 22.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) adh_short_C2 PF13561.6 EPS34717.1 - 3.5e-39 134.8 1.6 7.6e-38 130.4 1.6 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPS34717.1 - 1.1e-28 100.1 1.5 4e-28 98.2 1.5 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPS34717.1 - 3.6e-08 33.5 1.0 7.7e-08 32.5 0.4 1.7 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.15 EPS34717.1 - 0.031 13.4 0.1 0.042 13.0 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 EPS34717.1 - 0.1 12.0 0.1 0.45 9.9 0.1 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF4056 PF13265.6 EPS34717.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4056) DUF4054 PF13262.6 EPS34718.1 - 0.014 15.4 1.1 0.65 10.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4054) DUF1499 PF07386.11 EPS34718.1 - 0.23 12.0 1.9 5.7 7.5 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1499) DUF1455 PF07306.11 EPS34718.1 - 0.27 11.2 1.7 0.51 10.3 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1455) RabGAP-TBC PF00566.18 EPS34720.1 - 1.8e-47 161.8 0.0 3.3e-47 160.9 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.20 EPS34720.1 - 6.8e-05 22.7 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 GRAM domain FAM176 PF14851.6 EPS34720.1 - 7.5 6.2 6.4 8.1 6.1 0.2 2.8 2 0 0 2 2 2 0 FAM176 family CNH PF00780.22 EPS34721.1 - 2.7e-65 220.7 0.0 4.2e-65 220.1 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.20 EPS34721.1 - 6.4e-34 117.8 0.5 1.3e-33 116.8 0.5 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.6 EPS34721.1 - 1.7e-10 41.2 0.0 5.3e-10 39.5 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain 2OG-FeII_Oxy_2 PF13532.6 EPS34722.1 - 1e-26 94.3 0.0 1.6e-26 93.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AMP-binding PF00501.28 EPS34723.1 - 4e-80 269.5 0.0 5.2e-80 269.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EPS34723.1 - 1.1e-15 58.4 0.4 2.6e-15 57.2 0.4 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Abhydrolase_3 PF07859.13 EPS34724.1 - 3.3e-13 50.0 0.0 4.9e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EPS34724.1 - 3.1e-08 33.4 0.0 0.0013 18.3 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.7 EPS34724.1 - 8.2e-08 31.5 0.0 1.1e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.8 EPS34724.1 - 1.2e-07 31.3 0.1 2.2e-06 27.1 0.1 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase PF07224.11 EPS34724.1 - 8.8e-06 24.9 0.0 1.2e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Esterase PF00756.20 EPS34724.1 - 0.00084 19.0 0.1 0.003 17.2 0.1 1.9 1 1 1 2 2 2 1 Putative esterase AXE1 PF05448.12 EPS34724.1 - 0.0031 16.2 0.0 1.4 7.6 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) COesterase PF00135.28 EPS34724.1 - 0.0044 16.0 0.0 0.077 11.8 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family LIDHydrolase PF10230.9 EPS34724.1 - 0.037 13.6 0.0 7.5 6.0 0.0 2.1 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase WD40 PF00400.32 EPS34725.1 - 9e-16 58.0 2.5 0.0024 18.6 0.0 7.4 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS34725.1 - 2.4e-06 27.7 0.0 0.0013 19.0 0.0 3.4 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EPS34725.1 - 0.045 12.7 0.2 0.87 8.5 0.1 3.1 4 1 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein NDUF_B12 PF08122.12 EPS34727.1 - 1.4e-27 95.4 1.0 2e-27 95.0 1.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family CAF1 PF04857.20 EPS34728.1 - 3.2e-24 85.7 0.0 3.9e-11 42.7 0.0 2.1 2 0 0 2 2 2 2 CAF1 family ribonuclease Cu_amine_oxid PF01179.20 EPS34729.1 - 6.7e-161 535.8 0.0 8.1e-161 535.5 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.16 EPS34729.1 - 6.6e-23 81.0 0.4 4.3e-22 78.4 0.1 2.2 1 1 1 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.16 EPS34729.1 - 4.1e-13 49.4 0.0 8.2e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain TPR_2 PF07719.17 EPS34730.1 - 3.9e-08 32.8 3.5 0.0022 18.0 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EPS34730.1 - 0.00012 22.0 3.3 0.00056 19.9 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EPS34730.1 - 0.0002 21.9 0.5 0.082 13.6 0.1 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EPS34730.1 - 0.0003 20.5 2.1 0.4 10.6 0.4 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EPS34730.1 - 0.0016 18.7 2.8 2.1 8.7 0.0 2.9 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EPS34730.1 - 0.014 15.4 0.2 1.2 9.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EPS34730.1 - 0.033 14.7 0.0 2.4 8.7 0.0 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EPS34730.1 - 0.19 12.5 1.2 5 8.0 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat MARVEL PF01284.23 EPS34731.1 - 0.00036 20.6 9.6 0.00054 20.0 9.6 1.3 1 0 0 1 1 1 1 Membrane-associating domain CSG2 PF16965.5 EPS34731.1 - 0.033 13.1 0.0 0.045 12.7 0.0 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator DUF2561 PF10812.8 EPS34731.1 - 0.14 12.1 2.5 0.23 11.5 2.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2561) TMEM223 PF14640.6 EPS34731.1 - 0.15 12.2 0.4 0.25 11.5 0.4 1.3 1 0 0 1 1 1 0 Transmembrane protein 223 Ribosomal_S19e PF01090.19 EPS34734.1 - 0.067 12.9 0.0 0.092 12.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein S19e CPSF73-100_C PF11718.8 EPS34735.1 - 0.033 13.7 0.0 0.054 13.0 0.0 1.3 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Ank_2 PF12796.7 EPS34736.1 - 6.7e-25 87.5 0.0 9.4e-14 51.8 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPS34736.1 - 3.3e-23 81.7 0.2 6.2e-07 29.8 0.0 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EPS34736.1 - 9.6e-19 66.9 0.6 0.00027 21.3 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 EPS34736.1 - 9.8e-18 62.4 0.0 0.013 15.9 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EPS34736.1 - 1.6e-17 63.3 0.2 2.5e-08 34.0 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) F-box-like PF12937.7 EPS34736.1 - 3.5e-05 23.6 0.7 7.4e-05 22.6 0.7 1.5 1 0 0 1 1 1 1 F-box-like VWA_3_C PF18571.1 EPS34736.1 - 0.93 9.4 2.4 45 4.0 0.1 3.8 5 0 0 5 5 5 0 von Willebrand factor type A C-terminal domain Methyltransf_24 PF13578.6 EPS34737.1 - 2.1e-14 54.4 0.0 3.2e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.17 EPS34737.1 - 3.1e-14 52.6 0.0 4.2e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase CmcI PF04989.12 EPS34737.1 - 0.1 12.2 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Cephalosporin hydroxylase GFO_IDH_MocA PF01408.22 EPS34738.1 - 3e-27 95.8 0.2 5.2e-27 95.1 0.2 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EPS34738.1 - 3e-11 43.3 0.0 5.4e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.16 EPS34738.1 - 5.1e-07 30.3 0.1 9.7e-07 29.5 0.1 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.20 EPS34738.1 - 0.00021 21.4 0.1 0.00035 20.7 0.1 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus OCD_Mu_crystall PF02423.15 EPS34738.1 - 0.00044 19.3 0.0 0.00067 18.7 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Sacchrp_dh_NADP PF03435.18 EPS34738.1 - 0.0041 17.4 0.2 0.018 15.3 0.1 2.1 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain CoA_binding_2 PF13380.6 EPS34738.1 - 0.0046 17.4 0.2 0.012 16.1 0.2 1.6 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.19 EPS34738.1 - 0.0089 16.7 0.2 0.022 15.4 0.2 1.7 1 0 0 1 1 1 1 CoA binding domain ADH_zinc_N_2 PF13602.6 EPS34738.1 - 0.042 14.9 0.1 0.9 10.6 0.0 2.6 3 0 0 3 3 3 0 Zinc-binding dehydrogenase DUF402 PF04167.13 EPS34738.1 - 0.052 13.7 0.1 0.23 11.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF402) Peripla_BP_6 PF13458.6 EPS34738.1 - 0.082 12.6 0.1 1.5 8.4 0.0 2.1 2 0 0 2 2 2 0 Periplasmic binding protein Semialdhyde_dh PF01118.24 EPS34738.1 - 0.093 13.2 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain HPP PF04982.13 EPS34739.1 - 4.1e-35 120.6 11.2 4.5e-35 120.5 9.6 1.7 2 0 0 2 2 2 1 HPP family ABC_tran PF00005.27 EPS34740.1 - 1.3e-45 155.2 0.0 3.6e-22 79.4 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EPS34740.1 - 2.5e-21 75.5 1.1 2.5e-21 75.5 1.1 2.8 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EPS34740.1 - 1.5e-16 61.1 0.4 0.0018 18.2 0.1 4.2 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EPS34740.1 - 2.8e-10 40.0 0.6 0.013 14.9 0.1 4.5 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EPS34740.1 - 2.7e-08 33.4 0.5 0.0021 17.8 0.0 2.7 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EPS34740.1 - 3.3e-08 34.3 0.9 0.054 14.0 0.0 3.5 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 EPS34740.1 - 1.1e-06 28.6 0.2 0.0026 17.7 0.0 2.7 3 0 0 3 3 3 2 RsgA GTPase AAA_22 PF13401.6 EPS34740.1 - 3.7e-06 27.3 0.2 0.12 12.6 0.0 3.3 2 1 1 3 3 3 2 AAA domain AAA_15 PF13175.6 EPS34740.1 - 5.8e-06 26.3 0.1 0.037 13.7 0.0 2.8 3 0 0 3 3 3 2 AAA ATPase domain MMR_HSR1 PF01926.23 EPS34740.1 - 1.1e-05 25.4 0.2 0.015 15.4 0.0 3.0 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_18 PF13238.6 EPS34740.1 - 2.5e-05 24.8 0.0 0.066 13.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 EPS34740.1 - 2.7e-05 24.5 0.0 0.012 15.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EPS34740.1 - 2.9e-05 24.5 0.0 0.13 12.6 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 EPS34740.1 - 4.1e-05 24.0 0.0 0.55 10.7 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EPS34740.1 - 6.7e-05 22.9 0.4 0.077 12.9 0.0 2.5 2 0 0 2 2 2 2 NACHT domain RNA_helicase PF00910.22 EPS34740.1 - 7e-05 23.2 0.2 0.7 10.3 0.0 3.3 3 0 0 3 3 3 2 RNA helicase AAA_27 PF13514.6 EPS34740.1 - 0.00044 19.9 0.0 0.28 10.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 EPS34740.1 - 0.00067 18.9 0.0 1.5 7.9 0.0 3.1 3 0 0 3 3 3 2 NB-ARC domain AAA_24 PF13479.6 EPS34740.1 - 0.00098 18.9 0.7 1.9 8.2 0.0 3.4 3 1 0 3 3 3 1 AAA domain AAA_5 PF07728.14 EPS34740.1 - 0.0014 18.6 0.2 1.6 8.7 0.1 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EPS34740.1 - 0.0015 18.7 3.8 0.21 11.7 0.0 3.2 4 0 0 4 4 3 1 AAA domain Roc PF08477.13 EPS34740.1 - 0.0015 18.7 0.1 3.5 7.9 0.0 3.0 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 EPS34740.1 - 0.006 16.6 0.0 6 6.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EPS34740.1 - 0.0063 16.1 0.0 1.4 8.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 EPS34740.1 - 0.013 15.0 0.0 1.6 8.2 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF2813 PF11398.8 EPS34740.1 - 0.018 14.3 0.2 4.2 6.5 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) ATPase_2 PF01637.18 EPS34740.1 - 0.04 13.8 0.0 4.9 7.0 0.0 2.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 EPS34740.1 - 0.047 13.6 0.1 3.7 7.4 0.0 2.5 2 0 0 2 2 2 0 NTPase Ras PF00071.22 EPS34740.1 - 0.058 13.0 0.0 5.9 6.5 0.0 2.7 2 0 0 2 2 2 0 Ras family MCM PF00493.23 EPS34740.1 - 0.11 11.6 0.0 7 5.7 0.0 2.3 2 0 0 2 2 2 0 MCM P-loop domain DAP3 PF10236.9 EPS34740.1 - 0.14 11.3 0.5 8.3 5.5 0.0 2.6 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Rad17 PF03215.15 EPS34740.1 - 0.15 12.0 0.0 27 4.6 0.0 2.5 2 0 0 2 2 2 0 Rad17 P-loop domain FeoB_N PF02421.18 EPS34740.1 - 0.17 11.4 0.0 7 6.2 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_30 PF13604.6 EPS34740.1 - 0.36 10.5 2.6 4.8 6.9 0.1 3.3 3 1 0 3 3 2 0 AAA domain Dynamin_N PF00350.23 EPS34740.1 - 0.67 10.0 5.2 24 4.9 0.0 3.9 4 1 1 5 5 4 0 Dynamin family DUF87 PF01935.17 EPS34740.1 - 2.2 8.3 7.3 15 5.6 0.1 3.4 4 1 1 5 5 3 0 Helicase HerA, central domain Cyclin_C_2 PF16899.5 EPS34741.1 - 6.3e-38 129.4 0.1 3.6e-34 117.3 0.0 2.6 2 0 0 2 2 2 2 Cyclin C-terminal domain Cyclin_N PF00134.23 EPS34741.1 - 2.3e-06 27.3 0.0 5.9e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain UQ_con PF00179.26 EPS34742.1 - 1.2e-43 148.1 0.0 1.5e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 EPS34742.1 - 2e-05 24.3 0.0 3.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.6 EPS34742.1 - 0.00079 19.1 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EPS34742.1 - 0.011 15.6 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.22 EPS34742.1 - 0.036 14.4 0.0 0.054 13.8 0.0 1.4 1 0 0 1 1 1 0 RWD domain AAA PF00004.29 EPS34743.1 - 1.2e-40 139.0 0.0 2.3e-40 138.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EPS34743.1 - 2e-10 40.3 0.3 3.6e-10 39.5 0.3 1.4 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 EPS34743.1 - 1.3e-09 37.9 0.1 2.4e-09 37.0 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_5 PF07728.14 EPS34743.1 - 5.6e-06 26.4 0.0 1.6e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EPS34743.1 - 9.4e-06 25.9 0.2 0.018 15.3 0.1 2.6 1 1 1 2 2 2 2 AAA domain AAA_2 PF07724.14 EPS34743.1 - 1.3e-05 25.4 0.0 2.7e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 EPS34743.1 - 1.5e-05 24.3 0.0 2.5e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 EPS34743.1 - 0.00033 21.1 0.2 0.0036 17.7 0.2 2.3 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 EPS34743.1 - 0.00059 19.6 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EPS34743.1 - 0.0038 17.5 0.3 0.0089 16.3 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.6 EPS34743.1 - 0.011 16.3 0.3 0.025 15.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.6 EPS34743.1 - 0.016 15.4 0.0 0.033 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EPS34743.1 - 0.019 14.7 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.11 EPS34743.1 - 0.021 14.7 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 EPS34743.1 - 0.023 13.9 0.0 0.055 12.7 0.0 1.6 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_14 PF13173.6 EPS34743.1 - 0.032 14.3 0.0 0.062 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EPS34743.1 - 0.045 13.2 0.6 0.51 9.7 0.1 2.1 2 0 0 2 2 2 0 PhoH-like protein NACHT PF05729.12 EPS34743.1 - 0.045 13.7 0.1 0.63 9.9 0.1 2.2 1 1 1 2 2 2 0 NACHT domain ATPase PF06745.13 EPS34743.1 - 0.049 13.0 0.2 0.56 9.5 0.1 2.2 1 1 1 2 2 2 0 KaiC RNA_helicase PF00910.22 EPS34743.1 - 0.054 13.9 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 EPS34743.1 - 0.061 12.7 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 EPS34743.1 - 0.082 12.2 0.1 0.2 10.9 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 EPS34743.1 - 0.11 12.0 1.4 0.55 9.8 0.4 2.3 1 1 1 2 2 2 0 AAA domain Prot_ATP_OB_N PF17758.1 EPS34743.1 - 0.14 11.8 0.5 1 9.0 0.0 2.5 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain NTPase_1 PF03266.15 EPS34743.1 - 0.17 11.8 0.1 0.9 9.4 0.0 2.3 3 0 0 3 3 2 0 NTPase AAA_24 PF13479.6 EPS34743.1 - 0.21 11.3 2.3 0.33 10.7 0.3 2.3 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 EPS34743.1 - 0.21 10.8 0.1 0.3 10.3 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) WD40 PF00400.32 EPS34744.1 - 1e-13 51.5 13.9 0.0085 16.9 1.0 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS34744.1 - 0.00053 20.2 0.0 0.21 11.9 0.0 3.6 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain VID27_N PF17748.1 EPS34744.1 - 0.0067 16.3 0.2 0.092 12.6 0.4 2.2 2 0 0 2 2 2 1 VID27 N-terminal region PBP1_TM PF14812.6 EPS34744.1 - 0.04 14.3 8.4 0.14 12.6 8.4 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 EPS34744.1 - 0.094 13.1 11.6 0.2 12.1 11.6 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.12 EPS34744.1 - 0.55 9.5 7.0 0.84 8.9 7.0 1.2 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.11 EPS34744.1 - 0.84 9.6 5.3 1.9 8.5 5.3 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 EPS34744.1 - 2.2 8.0 4.3 4.5 6.9 4.3 1.4 1 0 0 1 1 1 0 FAM176 family DNA_pol_phi PF04931.13 EPS34744.1 - 8.2 4.4 8.8 11 3.9 8.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Mg_trans_NIPA PF05653.14 EPS34745.1 - 8.4e-62 208.9 9.2 1.3e-58 198.4 7.1 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.20 EPS34745.1 - 0.00019 21.6 0.8 0.00019 21.6 0.8 3.4 3 0 0 3 3 3 1 EamA-like transporter family DUF3040 PF11239.8 EPS34745.1 - 1.5 9.1 6.9 60 4.0 0.0 4.6 4 1 1 5 5 5 0 Protein of unknown function (DUF3040) Glyco_hydro_3 PF00933.21 EPS34746.1 - 5.1e-60 203.5 0.0 7.1e-60 203.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 EPS34746.1 - 1.2e-54 185.4 0.0 1.9e-54 184.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 EPS34746.1 - 3.2e-22 78.4 0.1 1.1e-21 76.8 0.1 2.0 1 0 0 1 1 1 1 Fibronectin type III-like domain Sugar-bind PF04198.13 EPS34746.1 - 0.018 14.2 0.0 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative sugar-binding domain SCP-1 PF05483.12 EPS34747.1 - 0.09 10.8 0.2 0.15 10.0 0.2 1.2 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) FlaC_arch PF05377.11 EPS34747.1 - 0.27 11.6 3.7 0.16 12.4 0.6 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Leu_zip PF15294.6 EPS34747.1 - 0.48 9.9 5.8 0.13 11.7 0.8 1.9 1 1 0 2 2 2 0 Leucine zipper DHR10 PF18595.1 EPS34747.1 - 0.85 9.7 12.7 0.052 13.6 3.7 2.4 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain SlyX PF04102.12 EPS34747.1 - 0.95 10.1 5.2 1.9 9.1 0.1 2.9 3 0 0 3 3 3 0 SlyX bZIP_1 PF00170.21 EPS34747.1 - 0.95 9.6 7.6 3.2 7.9 1.8 2.5 2 0 0 2 2 2 0 bZIP transcription factor Lebercilin PF15619.6 EPS34747.1 - 1.4 8.5 8.9 1.4 8.6 0.9 2.3 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease UPF0242 PF06785.11 EPS34747.1 - 1.6 8.8 4.1 17 5.5 0.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus ZapB PF06005.12 EPS34747.1 - 3.2 8.2 9.2 1.3 9.6 0.9 2.5 2 0 0 2 2 2 0 Cell division protein ZapB CdvA PF18822.1 EPS34747.1 - 6.6 6.6 7.3 1.2 9.0 1.8 2.2 2 0 0 2 2 2 0 CdvA-like coiled-coil domain VASt PF16016.5 EPS34748.1 - 2.2e-34 119.1 0.0 4.1e-34 118.2 0.0 1.4 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 EPS34748.1 - 3.5e-22 78.4 0.0 6e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 GRAM domain Sugar_tr PF00083.24 EPS34749.1 - 5.7e-59 200.2 15.4 6.5e-59 200.0 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Thioredoxin PF00085.20 EPS34750.1 - 3.8e-28 97.5 0.0 4.6e-28 97.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EPS34750.1 - 4.7e-08 33.2 0.0 1.7e-06 28.2 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EPS34750.1 - 1e-06 29.1 0.3 5.2e-06 26.9 0.2 2.0 2 1 0 2 2 2 1 Thioredoxin-like domain AhpC-TSA PF00578.21 EPS34750.1 - 1.8e-05 24.7 0.0 2.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EPS34750.1 - 2.2e-05 24.2 0.1 0.00013 21.7 0.1 1.9 1 1 1 2 2 2 1 Redoxin Thioredoxin_7 PF13899.6 EPS34750.1 - 4.1e-05 23.7 0.2 0.00018 21.6 0.2 1.9 1 1 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 EPS34750.1 - 8.8e-05 22.4 0.0 0.0001 22.2 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.6 EPS34750.1 - 0.0015 18.3 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 EPS34750.1 - 0.0049 16.3 0.0 0.0079 15.6 0.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family APOBEC4 PF18775.1 EPS34750.1 - 0.0081 16.3 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 APOBEC4 Thioredoxin_4 PF13462.6 EPS34750.1 - 0.12 12.5 0.5 0.87 9.7 0.1 2.0 1 1 1 2 2 2 0 Thioredoxin Hydrophobin PF01185.18 EPS34751.1 - 1.7e-08 34.9 6.7 2.5e-08 34.4 6.7 1.3 1 0 0 1 1 1 1 Fungal hydrophobin DUF2985 PF11204.8 EPS34752.1 - 3.2e-22 78.5 3.7 5.9e-22 77.6 3.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) LAP1C PF05609.12 EPS34753.1 - 0.16 11.0 6.3 0.21 10.6 6.3 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Apt1 PF10351.9 EPS34753.1 - 0.77 8.5 7.6 0.96 8.2 7.6 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain RRM_1 PF00076.22 EPS34754.1 - 5.3e-33 112.7 0.1 7e-16 57.8 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EPS34754.1 - 6.9e-06 26.1 0.0 0.0066 16.5 0.0 2.5 2 1 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 EPS34754.1 - 0.001 18.6 0.0 1.8 8.2 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 EPS34754.1 - 0.013 15.8 0.6 6 7.1 0.1 3.5 2 2 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter DUF4783 PF16022.5 EPS34754.1 - 0.044 14.0 0.0 0.21 11.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4783) RRM_Rrp7 PF17799.1 EPS34754.1 - 0.069 12.9 0.0 0.53 10.1 0.0 2.2 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain DNA_ligase_IV PF11411.8 EPS34754.1 - 0.2 11.8 0.5 25 5.1 0.1 2.6 2 0 0 2 2 2 0 DNA ligase IV ArfGap PF01412.18 EPS34755.1 - 1.7e-30 105.5 0.1 2.8e-30 104.8 0.1 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf GTP_EFTU PF00009.27 EPS34756.1 - 4.5e-55 186.2 0.0 6.6e-55 185.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 EPS34756.1 - 1.3e-25 89.3 0.1 3.4e-25 87.9 0.1 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 EPS34756.1 - 3.2e-15 55.9 0.1 5.4e-08 32.8 0.0 2.5 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EPS34756.1 - 2.7e-06 27.7 0.0 5.5e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EPS34756.1 - 0.00022 21.1 0.0 0.00043 20.1 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain EFG_IV PF03764.18 EPS34756.1 - 0.0057 16.4 0.0 3.9 7.3 0.0 2.8 2 1 0 3 3 3 2 Elongation factor G, domain IV DUF2095 PF09868.9 EPS34756.1 - 0.02 14.9 0.3 0.06 13.3 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2095) FTHFS PF01268.19 EPS34756.1 - 0.17 10.0 0.0 0.26 9.4 0.0 1.1 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase Vps5 PF09325.10 EPS34757.1 - 5.3e-14 52.3 1.5 9.2e-14 51.6 1.5 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 EPS34757.1 - 5.6e-11 42.4 0.0 1.1e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 PX domain KAsynt_C_assoc PF16197.5 EPS34757.1 - 0.07 13.6 0.6 0.17 12.4 0.6 1.6 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension Response_reg PF00072.24 EPS34758.1 - 6.4e-22 77.9 0.1 3.6e-21 75.4 0.2 2.3 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 EPS34758.1 - 1.3e-16 61.1 0.0 3.5e-16 59.7 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EPS34758.1 - 4.6e-14 52.2 0.0 2e-13 50.2 0.0 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain NAD_binding_10 PF13460.6 EPS34760.1 - 1.5e-10 41.2 0.0 2.4e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EPS34760.1 - 1.1e-08 34.9 0.0 1.7e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.24 EPS34760.1 - 1.9e-07 31.5 0.0 3.4e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 EPS34760.1 - 5.4e-07 29.3 0.0 0.00081 18.9 0.1 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EPS34760.1 - 6.3e-05 22.3 0.0 0.00012 21.3 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 EPS34760.1 - 0.00068 18.7 0.0 0.0025 16.9 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EPS34760.1 - 0.0096 15.1 0.0 0.084 12.0 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EPS34760.1 - 0.015 14.5 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DXP_reductoisom PF02670.16 EPS34760.1 - 0.049 14.3 0.0 0.085 13.6 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DapB_N PF01113.20 EPS34760.1 - 0.099 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus RNHCP PF12647.7 EPS34760.1 - 0.14 12.2 0.1 0.24 11.4 0.1 1.3 1 0 0 1 1 1 0 RNHCP domain THOC2_N PF16134.5 EPS34761.1 - 3.4e-245 815.5 0.0 7.3e-245 814.4 0.0 1.5 2 0 0 2 2 2 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 EPS34761.1 - 8e-103 343.8 0.0 1.3e-102 343.1 0.0 1.4 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 EPS34761.1 - 2.6e-30 104.3 0.0 7.1e-30 102.9 0.0 1.8 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Abhydrolase_1 PF00561.20 EPS34763.1 - 1.3e-49 169.2 0.1 1.7e-49 168.8 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPS34763.1 - 0.0011 19.6 8.0 0.0064 17.1 8.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ribosomal_L7Ae PF01248.26 EPS34764.1 - 1.8e-24 85.3 0.0 2e-24 85.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SAP PF02037.27 EPS34765.1 - 5.4e-09 35.6 0.1 1.1e-08 34.6 0.1 1.6 1 0 0 1 1 1 1 SAP domain RSB_motif PF16294.5 EPS34765.1 - 5.3e-05 23.4 0.0 5.3e-05 23.4 0.0 3.9 4 1 0 4 4 4 1 RNSP1-SAP18 binding (RSB) motif Ish1 PF10281.9 EPS34765.1 - 0.023 15.0 0.0 0.28 11.5 0.0 2.6 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein Solute_trans_a PF03619.16 EPS34766.1 - 1.1e-91 307.1 22.9 1.3e-91 306.8 22.9 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha TssN PF17555.2 EPS34766.1 - 7.3 5.9 17.0 0.55 9.6 1.4 2.2 2 0 0 2 2 2 0 Type VI secretion system, TssN MitMem_reg PF13012.6 EPS34767.1 - 1.7e-14 54.2 0.4 4.2e-14 52.9 0.4 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EPS34767.1 - 3.9e-09 36.5 0.0 8.6e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease RNA_pol_3_Rpc31 PF11705.8 EPS34769.1 - 1.2e-60 205.6 13.4 1.5e-60 205.3 13.4 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 TFIIA PF03153.13 EPS34769.1 - 0.27 11.2 4.6 0.28 11.1 4.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Flavodoxin_1 PF00258.25 EPS34770.1 - 3.6e-32 111.6 0.0 5.8e-32 110.9 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.20 EPS34770.1 - 6.1e-29 101.2 0.0 9.2e-29 100.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EPS34770.1 - 4.8e-16 59.4 0.0 1.1e-14 55.0 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 EPS34770.1 - 0.00019 21.7 0.0 0.015 15.5 0.0 2.7 2 1 1 3 3 3 1 Flavodoxin domain FAD_binding_6 PF00970.24 EPS34770.1 - 0.059 13.7 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Flavodoxin_3 PF12641.7 EPS34770.1 - 0.14 11.9 0.0 0.56 9.9 0.0 1.9 2 0 0 2 2 2 0 Flavodoxin domain ETF PF01012.21 EPS34771.1 - 1.7e-42 145.4 0.3 2e-42 145.1 0.3 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Ysc84 PF04366.12 EPS34773.1 - 1.2e-46 157.6 0.0 2.2e-46 156.8 0.0 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator Fungal_trans_2 PF11951.8 EPS34775.1 - 4.4e-06 25.8 1.4 6.5e-05 21.9 0.2 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Trp_DMAT PF11991.8 EPS34776.1 - 9.2e-49 166.8 0.0 1.3e-47 163.0 0.0 1.9 2 0 0 2 2 2 2 Tryptophan dimethylallyltransferase Trp_DMAT PF11991.8 EPS34777.1 - 6.9e-13 48.7 0.1 7.8e-13 48.6 0.1 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase p450 PF00067.22 EPS34778.1 - 7.6e-58 196.4 0.0 1.1e-55 189.2 0.0 2.6 1 1 1 2 2 2 1 Cytochrome P450 NAD_binding_4 PF07993.12 EPS34779.1 - 2.5e-21 76.0 0.0 4.4e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Abhydrolase_3 PF07859.13 EPS34779.1 - 1.2e-14 54.7 0.0 2.8e-12 47.0 0.0 2.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold AMP-binding PF00501.28 EPS34779.1 - 1.9e-12 46.5 0.1 1.1e-05 24.2 0.0 2.4 1 1 1 2 2 2 2 AMP-binding enzyme Epimerase PF01370.21 EPS34779.1 - 1.5e-07 31.1 0.0 3.2e-07 30.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Peptidase_S9 PF00326.21 EPS34779.1 - 6.8e-06 25.7 0.0 0.0027 17.2 0.0 2.5 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EPS34779.1 - 6.1e-05 23.7 3.3 0.00013 22.7 1.2 2.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.18 EPS34779.1 - 0.0055 16.3 0.0 0.39 10.2 0.0 2.3 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 EPS34779.1 - 0.017 14.8 0.1 9.3 5.8 0.0 3.3 3 0 0 3 3 3 0 alpha/beta hydrolase fold PP-binding PF00550.25 EPS34779.1 - 0.022 15.1 0.1 0.18 12.2 0.0 2.6 3 0 0 3 3 3 0 Phosphopantetheine attachment site Glyco_trans_1_4 PF13692.6 EPS34779.1 - 0.029 14.8 0.2 12 6.3 0.0 2.8 2 0 0 2 2 2 0 Glycosyl transferases group 1 Myb_DNA-binding PF00249.31 EPS34780.1 - 5.3e-32 109.8 9.0 1.3e-10 41.3 0.0 3.8 3 1 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EPS34780.1 - 7.4e-25 87.0 8.8 3e-09 37.0 0.6 3.7 1 1 2 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.8 EPS34780.1 - 0.00038 20.5 3.2 7.9 6.7 0.0 3.2 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_7 PF15963.5 EPS34780.1 - 0.0045 16.9 0.6 6.2 6.8 0.0 3.0 1 1 2 3 3 3 2 Myb DNA-binding like MADF_DNA_bdg PF10545.9 EPS34780.1 - 0.032 14.5 5.7 0.46 10.8 0.2 2.8 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_2 PF08914.11 EPS34780.1 - 0.043 14.0 2.4 3.8 7.8 0.0 3.0 3 0 0 3 3 3 0 Rap1 Myb domain SANT_DAMP1_like PF16282.5 EPS34780.1 - 0.25 11.6 0.2 0.25 11.6 0.2 2.7 2 1 1 3 3 3 0 SANT/Myb-like domain of DAMP1 adh_short PF00106.25 EPS34781.1 - 1.8e-19 70.0 3.0 8.2e-18 64.6 1.3 2.2 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.10 EPS34781.1 - 8.1e-15 55.2 0.1 1.3e-14 54.6 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EPS34781.1 - 1.1e-11 44.7 1.5 1.1e-09 38.2 0.5 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase H_PPase PF03030.16 EPS34781.1 - 0.0078 14.9 0.1 0.012 14.3 0.1 1.2 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase RNA_lig_T4_1 PF09511.10 EPS34781.1 - 0.093 12.6 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA ligase Herpes_BBRF1 PF04793.12 EPS34781.1 - 0.098 11.7 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 BRRF1-like protein adh_short PF00106.25 EPS34782.1 - 7.2e-19 68.0 0.0 9.2e-19 67.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS34782.1 - 5.2e-14 52.4 0.0 1.1e-13 51.4 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPS34782.1 - 0.001 19.0 0.0 0.002 18.1 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EPS34782.1 - 0.011 15.2 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ThiF PF00899.21 EPS34782.1 - 0.14 11.5 0.1 0.24 10.7 0.1 1.3 1 0 0 1 1 1 0 ThiF family FAD_binding_4 PF01565.23 EPS34783.1 - 1.5e-20 73.4 0.5 2.3e-20 72.7 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EPS34783.1 - 0.0014 18.7 0.1 0.0034 17.4 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.22 EPS34784.1 - 1.9e-60 205.0 0.0 2.4e-60 204.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PARP PF00644.20 EPS34785.1 - 2.8e-10 40.1 0.0 5.3e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PTCB-BRCT PF12738.7 EPS34785.1 - 0.015 15.3 0.3 0.039 13.9 0.0 1.9 2 0 0 2 2 2 0 twin BRCT domain BRCT_2 PF16589.5 EPS34785.1 - 0.084 13.3 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EPS34785.1 - 0.14 12.4 0.0 0.42 10.9 0.0 1.7 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain PARP PF00644.20 EPS34786.1 - 2.7e-32 112.0 0.0 6.1e-32 110.8 0.0 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain BRCT PF00533.26 EPS34786.1 - 3.5e-07 30.5 0.1 9.6e-07 29.1 0.1 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EPS34786.1 - 0.001 19.4 0.0 0.0066 16.8 0.0 2.2 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 EPS34786.1 - 0.0028 17.6 0.2 0.0067 16.3 0.2 1.7 1 0 0 1 1 1 1 twin BRCT domain NAD_binding_10 PF13460.6 EPS34787.1 - 1.8e-09 37.7 0.0 2.6e-09 37.2 0.0 1.3 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EPS34787.1 - 3.3e-06 26.7 0.0 7.9e-06 25.5 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 EPS34787.1 - 8.6e-05 22.2 0.3 8.6e-05 22.2 0.3 1.9 2 1 0 2 2 2 1 NmrA-like family HIM1 PF08732.10 EPS34787.1 - 0.0003 20.4 0.0 0.00042 19.9 0.0 1.2 1 0 0 1 1 1 1 HIM1 NAD_binding_4 PF07993.12 EPS34787.1 - 0.022 13.9 0.0 0.86 8.7 0.0 2.2 1 1 1 2 2 2 0 Male sterility protein Semialdhyde_dh PF01118.24 EPS34787.1 - 0.11 12.9 0.1 0.29 11.6 0.1 2.0 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Peroxin-3 PF04882.12 EPS34788.1 - 3.6e-166 553.8 4.7 3.6e-166 553.8 4.7 1.4 2 0 0 2 2 2 1 Peroxin-3 Anillin_N PF16018.5 EPS34788.1 - 0.058 14.0 0.8 2.8 8.6 0.1 2.9 2 1 0 2 2 2 0 Anillin N-terminus ATG101 PF07855.12 EPS34789.1 - 1.2e-53 181.3 0.0 1.3e-53 181.1 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 101 TB2_DP1_HVA22 PF03134.19 EPS34790.1 - 7.1e-28 96.4 8.1 7.1e-28 96.4 8.1 1.6 2 0 0 2 2 2 1 TB2/DP1, HVA22 family Ras PF00071.22 EPS34791.1 - 2e-51 173.8 0.0 2.3e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EPS34791.1 - 5.3e-19 68.6 0.0 7e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EPS34791.1 - 5.1e-10 39.1 0.0 5.6e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EPS34791.1 - 2.2e-05 24.1 0.0 0.00016 21.3 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EPS34791.1 - 9.9e-05 22.4 0.0 0.00014 21.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EPS34791.1 - 0.0018 18.2 0.1 1.5 8.7 0.1 2.2 1 1 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 EPS34791.1 - 0.031 14.5 0.1 0.32 11.3 0.1 2.2 1 1 0 1 1 1 0 AAA domain Carboxyl_trans PF01039.22 EPS34792.1 - 4e-138 461.1 0.4 5.2e-138 460.8 0.4 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain Acyl-CoA_dh_1 PF00441.24 EPS34793.1 - 9.7e-41 139.5 0.9 1.5e-40 138.8 0.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EPS34793.1 - 8.7e-34 116.6 0.2 1.7e-33 115.6 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EPS34793.1 - 2.9e-28 97.9 0.2 5.6e-28 97.0 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EPS34793.1 - 5.6e-13 49.3 0.0 9.1e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 EPS34793.1 - 2.6e-05 24.0 0.1 7.7e-05 22.5 0.1 1.7 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal FAD_binding_3 PF01494.19 EPS34794.1 - 2.8e-67 227.5 0.0 3.6e-67 227.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.12 EPS34794.1 - 5.8e-35 120.8 0.0 1.1e-34 119.9 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox PF00070.27 EPS34794.1 - 0.0019 18.7 0.0 0.037 14.6 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EPS34794.1 - 0.0038 16.5 0.0 0.081 12.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPS34794.1 - 0.047 13.9 0.1 0.19 12.0 0.1 2.1 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EPS34794.1 - 0.083 12.1 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Thi4 family UDPG_MGDP_dh_N PF03721.14 EPS34794.1 - 0.22 11.1 0.1 0.41 10.2 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Aminotran_1_2 PF00155.21 EPS34795.1 - 5.1e-13 48.9 0.0 7e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EPS34795.1 - 1.3e-05 24.2 0.0 5.4e-05 22.2 0.0 1.8 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Integrase_H2C2 PF17921.1 EPS34795.1 - 0.11 12.6 0.1 0.31 11.2 0.1 1.7 2 0 0 2 2 2 0 Integrase zinc binding domain DOPA_dioxygen PF08883.11 EPS34796.1 - 2.6e-38 130.5 0.1 3.4e-38 130.1 0.1 1.2 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family Glyoxalase PF00903.25 EPS34797.1 - 9.7e-19 67.8 0.2 1.1e-12 48.3 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EPS34797.1 - 1.4e-10 41.4 0.0 0.00094 19.4 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 EPS34797.1 - 1.7e-06 28.3 0.1 1.9e-05 24.9 0.0 2.5 3 0 0 3 3 3 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 EPS34797.1 - 5.7e-05 23.3 0.0 0.36 10.9 0.0 3.1 2 2 0 2 2 2 2 Glyoxalase-like domain FMN_dh PF01070.18 EPS34798.1 - 4.8e-108 361.3 0.0 5.7e-108 361.0 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 EPS34798.1 - 4.2e-17 62.1 0.0 9.2e-17 61.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 EPS34798.1 - 0.00042 19.6 0.0 0.00062 19.0 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 EPS34798.1 - 0.00049 19.2 0.1 0.0027 16.8 0.0 1.9 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 EPS34798.1 - 0.04 13.3 0.1 0.07 12.5 0.1 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase ThiG PF05690.14 EPS34798.1 - 0.069 12.4 0.2 0.21 10.9 0.0 1.8 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG MFS_1 PF07690.16 EPS34800.1 - 9.7e-47 159.6 59.4 5e-42 144.1 46.0 3.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_A14 PF05767.12 EPS34800.1 - 0.1 12.8 3.1 0.12 12.6 0.1 2.8 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 DUF2681 PF10883.8 EPS34800.1 - 8.2 6.9 5.4 3 8.3 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) Sugar_tr PF00083.24 EPS34803.1 - 4.7e-109 365.2 25.2 6.7e-109 364.7 25.2 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS34803.1 - 5.8e-27 94.5 30.3 2e-20 73.0 9.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Amidohydro_1 PF01979.20 EPS34804.1 - 2e-20 73.4 4.3 1.7e-19 70.3 4.3 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EPS34804.1 - 6.1e-14 52.3 3.8 3.4e-07 30.1 0.4 2.8 1 1 1 2 2 2 2 Amidohydrolase family CPSase_L_D2 PF02786.17 EPS34805.1 - 5.6e-73 244.9 0.0 1.1e-72 244.0 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 EPS34805.1 - 1.3e-36 125.0 0.0 3.5e-36 123.6 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 EPS34805.1 - 3.9e-35 120.7 0.0 8.3e-35 119.7 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 EPS34805.1 - 2.1e-17 62.7 0.6 8.6e-17 60.7 0.2 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EPS34805.1 - 3.8e-09 36.4 0.0 8.9e-09 35.2 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EPS34805.1 - 6.8e-08 32.3 0.0 1.4e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 EPS34805.1 - 4.8e-06 26.3 0.5 0.021 14.6 0.1 3.0 2 1 1 3 3 3 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 EPS34805.1 - 0.00019 21.5 0.0 0.00037 20.6 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 EPS34805.1 - 0.00045 20.9 0.2 1.5 9.6 0.0 2.8 2 0 0 2 2 2 2 HlyD family secretion protein GARS_A PF01071.19 EPS34805.1 - 0.0062 16.3 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_ST PF14397.6 EPS34805.1 - 0.0069 15.7 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp GCV_H PF01597.19 EPS34805.1 - 0.043 13.7 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein RimK PF08443.11 EPS34805.1 - 0.048 13.2 0.0 0.22 11.1 0.0 2.0 2 0 0 2 2 2 0 RimK-like ATP-grasp domain HlyD_D23 PF16576.5 EPS34805.1 - 0.066 12.4 0.1 7.5 5.7 0.0 2.4 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_4 PF13535.6 EPS34805.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain adh_short_C2 PF13561.6 EPS34806.1 - 1.3e-53 182.0 0.0 1.8e-53 181.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPS34806.1 - 1.7e-36 125.5 0.1 2.3e-36 125.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPS34806.1 - 7.6e-13 48.8 0.1 1.1e-12 48.2 0.1 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EPS34806.1 - 0.0037 16.7 0.0 0.77 9.1 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Ead_Ea22 PF13935.6 EPS34806.1 - 0.11 13.2 0.1 0.19 12.4 0.1 1.3 1 0 0 1 1 1 0 Ead/Ea22-like protein MARVEL PF01284.23 EPS34807.1 - 7.5e-06 26.0 2.7 7.5e-06 26.0 2.7 1.9 2 1 0 2 2 2 1 Membrane-associating domain DUF2434 PF10361.9 EPS34807.1 - 0.1 11.6 1.5 0.15 11.1 0.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2434) FA_desaturase PF00487.24 EPS34807.1 - 0.22 11.3 7.1 0.06 13.2 2.6 2.2 1 1 1 2 2 2 0 Fatty acid desaturase APCDDC PF14921.6 EPS34809.1 - 0.1 12.0 0.1 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 Adenomatosis polyposis coli down-regulated 1 PHD PF00628.29 EPS34810.1 - 8.5e-10 38.4 2.0 1.9e-09 37.2 2.0 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 EPS34810.1 - 0.0052 16.3 2.5 0.0083 15.7 2.5 1.3 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.15 EPS34810.1 - 0.17 12.0 1.6 0.43 10.7 1.6 1.7 1 0 0 1 1 1 0 CW-type Zinc Finger C1_1 PF00130.22 EPS34810.1 - 0.83 9.6 3.7 1.2 9.1 0.3 2.2 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) eIF-5a PF01287.20 EPS34811.1 - 1.8e-05 24.8 0.0 3.7e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold SelP_N PF04592.14 EPS34811.1 - 1.6 8.1 10.0 0.05 13.0 3.4 1.7 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Abhydrolase_1 PF00561.20 EPS34814.1 - 1.2e-19 70.9 0.0 2.1e-19 70.2 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPS34814.1 - 6.2e-15 56.4 9.7 1.4e-13 52.0 9.7 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPS34814.1 - 3.1e-12 46.3 0.0 4.5e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase_phd PF10503.9 EPS34814.1 - 0.00011 21.8 0.2 0.00021 20.9 0.2 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase Esterase PF00756.20 EPS34814.1 - 0.00026 20.7 0.0 0.00063 19.5 0.0 1.5 1 1 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 EPS34814.1 - 0.006 15.5 0.0 0.0093 14.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 EPS34814.1 - 0.16 11.0 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase SET PF00856.28 EPS34815.1 - 5.9e-13 49.6 0.2 3.6e-12 47.0 0.2 2.1 1 1 0 1 1 1 1 SET domain SRR1 PF07985.12 EPS34818.1 - 1.7e-17 63.2 0.0 3.3e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 SRR1 RRP7 PF12923.7 EPS34818.1 - 0.00088 19.4 0.6 0.0014 18.7 0.6 1.4 1 1 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain DUF2812 PF11193.8 EPS34818.1 - 0.061 13.5 0.1 0.31 11.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2812) CAF20 PF17052.5 EPS34818.1 - 0.092 12.9 0.4 0.18 12.0 0.4 1.4 1 0 0 1 1 1 0 Cap associated factor Glyco_hydro_17 PF00332.18 EPS34819.1 - 9.6e-09 35.3 5.4 8.7e-06 25.5 0.7 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 DUF1269 PF06897.12 EPS34819.1 - 0.51 10.7 5.7 0.19 12.0 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) Spc110_C PF18520.1 EPS34827.1 - 0.041 13.5 0.0 0.061 12.9 0.0 1.2 1 0 0 1 1 1 0 Spindle pole body component 110 C-terminal domain DHHC PF01529.20 EPS34828.1 - 1.2e-27 96.7 6.0 1.2e-27 96.7 6.0 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF4131 PF13567.6 EPS34828.1 - 2.8 7.6 4.7 2 8.1 1.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Zn_clus PF00172.18 EPS34832.1 - 2.8e-08 33.7 6.5 7.6e-08 32.3 6.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.12 EPS34833.1 - 0.00062 19.6 0.0 0.0064 16.4 0.0 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EPS34833.1 - 0.095 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase zf-C3H1 PF10650.9 EPS34834.1 - 1.9e-12 46.7 3.1 2.9e-12 46.0 3.1 1.3 1 0 0 1 1 1 1 Putative zinc-finger domain Myosin_head PF00063.21 EPS34835.1 - 2e-265 882.3 1.4 2.6e-265 881.9 0.0 2.0 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 EPS34835.1 - 7.6e-21 73.7 284.5 1e-15 56.8 193.9 4.5 1 1 1 2 2 2 2 Myosin tail Myosin_N PF02736.19 EPS34835.1 - 5.1e-10 39.0 0.0 1.3e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 EPS34835.1 - 0.17 12.1 0.0 0.17 12.1 0.0 5.4 4 1 0 4 4 4 0 AAA domain Isy1 PF06246.12 EPS34836.1 - 7.6e-87 291.1 0.2 8.8e-87 290.9 0.2 1.0 1 0 0 1 1 1 1 Isy1-like splicing family YolD PF08863.10 EPS34836.1 - 0.079 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 YolD-like protein MMR_HSR1 PF01926.23 EPS34837.1 - 8.1e-13 48.5 0.0 5e-12 45.9 0.0 2.1 2 1 1 3 3 3 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EPS34837.1 - 0.00011 22.2 0.0 0.00026 20.9 0.0 1.6 1 1 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 EPS34837.1 - 0.00011 21.7 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.16 EPS34837.1 - 0.00068 19.0 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 AIG1 family Septin PF00735.18 EPS34837.1 - 0.014 14.7 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_16 PF13191.6 EPS34837.1 - 0.042 14.2 0.1 0.13 12.6 0.0 1.8 2 1 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.23 EPS34837.1 - 0.13 12.3 0.1 1.3 9.0 0.0 2.3 1 1 1 2 2 2 0 Dynamin family HCO3_cotransp PF00955.21 EPS34838.1 - 2.3e-65 221.4 18.1 2e-39 135.8 0.4 2.1 1 1 1 2 2 2 2 HCO3- transporter family ASFV_J13L PF05568.11 EPS34838.1 - 0.0066 16.2 0.3 0.014 15.1 0.3 1.5 1 0 0 1 1 1 1 African swine fever virus J13L protein PI3Ka PF00613.20 EPS34839.1 - 3.4e-60 202.6 0.2 5.4e-60 202.0 0.2 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 EPS34839.1 - 3.3e-45 154.9 0.0 1.2e-31 110.4 0.0 2.8 2 1 1 3 3 3 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 EPS34839.1 - 8.8e-29 100.2 0.0 1.5e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Nse4_C PF08743.10 EPS34840.1 - 5.2e-30 103.6 0.0 1.4e-29 102.2 0.0 1.8 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 EPS34840.1 - 3.3e-16 59.1 0.0 8.5e-16 57.8 0.0 1.7 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE DUF4336 PF14234.6 EPS34841.1 - 2.3e-16 59.9 0.0 3.7e-12 46.1 0.0 2.4 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) MARVEL PF01284.23 EPS34842.1 - 3.4e-09 36.9 7.1 5e-09 36.3 7.1 1.2 1 0 0 1 1 1 1 Membrane-associating domain LCCL PF03815.19 EPS34843.1 - 1.3e-20 73.3 0.0 2.2e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 LCCL domain Metallophos PF00149.28 EPS34844.1 - 9.4e-12 45.9 0.0 1.8e-11 44.9 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EPS34844.1 - 0.00025 21.3 1.7 0.001 19.3 1.7 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain zf-RING_13 PF17977.1 EPS34844.1 - 0.11 12.7 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain ThiF PF00899.21 EPS34845.1 - 8.1e-42 143.3 0.0 1.4e-41 142.5 0.0 1.3 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 EPS34845.1 - 0.00069 19.9 0.4 0.013 15.8 0.4 2.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 EPS34845.1 - 0.0032 17.7 0.0 0.0093 16.2 0.0 1.8 1 0 0 1 1 1 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 EPS34845.1 - 0.015 14.9 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 EPS34845.1 - 0.021 14.5 0.1 0.038 13.6 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.6 EPS34845.1 - 0.028 14.9 0.0 0.09 13.2 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Abhydrolase_1 PF00561.20 EPS34846.1 - 1.5e-47 162.4 0.0 1.3e-46 159.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EPS34846.1 - 0.00057 19.6 0.0 0.0011 18.7 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Glyco_hydro_43 PF04616.14 EPS34847.1 - 5e-33 114.6 0.0 1.5e-32 113.1 0.0 1.6 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.20 EPS34847.1 - 0.0029 17.2 0.0 0.097 12.2 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Gly_transf_sug PF04488.15 EPS34848.1 - 6.2e-14 52.4 0.0 1.2e-13 51.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Pkinase PF00069.25 EPS34849.1 - 5e-64 216.2 0.0 5.9e-64 216.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS34849.1 - 4.3e-36 124.5 0.0 5.5e-36 124.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EPS34849.1 - 2.5e-05 23.4 0.0 3.4e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EPS34849.1 - 0.012 15.5 0.0 0.19 11.6 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EPS34849.1 - 0.056 12.7 0.0 0.088 12.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Seadorna_VP7 PF07387.11 EPS34849.1 - 0.06 12.4 0.0 0.094 11.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 ATP-synt_C PF00137.21 EPS34850.1 - 2.3e-29 101.5 35.2 2.7e-18 66.1 13.3 2.1 2 0 0 2 2 2 2 ATP synthase subunit C PIRT PF15099.6 EPS34850.1 - 2.3 7.8 6.2 0.37 10.4 0.6 1.9 1 1 0 2 2 2 0 Phosphoinositide-interacting protein family CNH PF00780.22 EPS34852.1 - 3.4e-83 279.4 0.0 2e-82 276.9 0.0 1.9 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 EPS34852.1 - 1.8e-42 144.6 0.0 5.2e-42 143.1 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.20 EPS34852.1 - 5.5e-39 134.3 0.0 1.2e-38 133.2 0.0 1.6 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.21 EPS34852.1 - 2.9e-14 52.8 0.0 8.3e-14 51.4 0.0 1.8 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) YorP PF09629.10 EPS34852.1 - 0.053 13.7 0.1 22 5.4 0.0 2.6 2 0 0 2 2 2 0 YorP protein Septin PF00735.18 EPS34854.1 - 3.8e-106 354.5 0.1 6.6e-106 353.7 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EPS34854.1 - 2.3e-05 24.5 0.0 6.3e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EPS34854.1 - 0.012 15.2 0.2 0.85 9.1 0.0 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EPS34854.1 - 0.033 14.1 4.8 0.041 13.8 0.6 2.8 3 1 0 3 3 3 0 RsgA GTPase AAA_22 PF13401.6 EPS34854.1 - 0.21 11.9 1.2 0.41 10.9 0.0 2.1 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 EPS34854.1 - 0.25 11.4 5.2 3.1 7.8 0.0 3.0 2 1 1 3 3 3 0 Dynamin family WD40 PF00400.32 EPS34855.1 - 3.5e-06 27.6 0.0 0.05 14.5 0.0 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS34855.1 - 1.9e-05 24.8 0.0 0.00057 20.1 0.0 2.7 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EPS34855.1 - 0.016 14.2 0.0 0.34 9.8 0.0 2.2 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 EPS34855.1 - 0.047 11.7 0.0 0.059 11.4 0.0 1.2 1 0 0 1 1 1 0 IKI3 family Nbas_N PF15492.6 EPS34855.1 - 0.12 11.7 0.0 2.1 7.6 0.0 2.2 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal RRM_1 PF00076.22 EPS34856.1 - 6.7e-18 64.3 0.0 1.4e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EPS34856.1 - 2.8e-05 24.2 0.0 8.6e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif RRM_5 PF13893.6 EPS34856.1 - 0.075 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ECSIT_C PF14784.6 EPS34856.1 - 0.18 12.1 0.2 0.38 11.1 0.2 1.5 1 0 0 1 1 1 0 C-terminal domain of the ECSIT protein DLIC PF05783.11 EPS34857.1 - 1.4e-38 133.0 2.7 6.3e-34 117.6 0.0 3.6 2 2 0 2 2 2 2 Dynein light intermediate chain (DLIC) DUF1456 PF07308.13 EPS34857.1 - 0.096 13.0 0.2 0.62 10.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) Spermine_synth PF01564.17 EPS34858.1 - 8e-10 38.4 0.0 1.4e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Methyltransf_23 PF13489.6 EPS34858.1 - 0.0032 17.3 0.0 0.0059 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_30 PF05430.11 EPS34858.1 - 0.034 14.0 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase DUF2052 PF09747.9 EPS34859.1 - 1.7e-21 77.3 17.9 4.6e-12 46.5 0.9 2.1 1 1 1 2 2 2 2 Coiled-coil domain containing protein (DUF2052) AMP-binding PF00501.28 EPS34860.1 - 1.9e-97 326.5 0.0 2.4e-97 326.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EPS34860.1 - 3e-17 63.4 0.0 6.6e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Adap_comp_sub PF00928.21 EPS34861.1 - 9.6e-92 307.1 0.0 1.7e-91 306.3 0.0 1.4 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EPS34861.1 - 1.4e-08 34.8 0.2 2.3e-08 34.1 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 EPS34861.1 - 0.11 11.9 0.0 0.31 10.5 0.0 1.6 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain Ribonucleas_3_3 PF14622.6 EPS34862.1 - 3e-28 98.6 0.0 4.7e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EPS34862.1 - 4.5e-06 27.2 0.0 1.3e-05 25.8 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain Sdh_cyt PF01127.22 EPS34864.1 - 9e-25 87.1 4.7 1.1e-24 86.7 4.7 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit NMO PF03060.15 EPS34865.1 - 1.7e-54 185.4 0.1 2.3e-53 181.7 0.1 1.9 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EPS34865.1 - 3.9e-14 52.4 0.0 8.8e-12 44.7 0.0 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EPS34865.1 - 0.00089 18.4 0.1 0.0016 17.6 0.1 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 EPS34865.1 - 0.065 12.4 0.7 0.23 10.6 0.7 1.9 1 1 0 1 1 1 0 Conserved region in glutamate synthase DUF1902 PF08972.11 EPS34865.1 - 0.075 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) NanE PF04131.14 EPS34865.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.5 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Tad PF13400.6 EPS34867.1 - 0.06 13.7 1.7 0.12 12.7 1.7 1.4 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like Hydrophobin PF01185.18 EPS34868.1 - 2.1e-09 37.9 6.7 3e-09 37.4 6.7 1.3 1 0 0 1 1 1 1 Fungal hydrophobin WW PF00397.26 EPS34870.1 - 3.5e-09 36.6 0.4 8.5e-09 35.4 0.4 1.7 1 0 0 1 1 1 1 WW domain WRW PF10206.9 EPS34870.1 - 0.036 14.4 0.8 0.22 11.9 0.3 2.1 2 0 0 2 2 2 0 Mitochondrial F1F0-ATP synthase, subunit f Ank_2 PF12796.7 EPS34871.1 - 5.3e-13 49.4 0.1 2.5e-12 47.2 0.2 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EPS34871.1 - 6.3e-13 49.0 0.1 4.6e-07 30.2 0.0 2.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EPS34871.1 - 4e-10 39.7 0.2 4.6e-07 30.0 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EPS34871.1 - 4.2e-08 32.8 0.1 2.6e-06 27.3 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 EPS34871.1 - 1.6e-07 31.4 0.8 1.1e-06 28.8 0.3 2.3 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Glyco_transf_21 PF13506.6 EPS34872.1 - 1.1e-13 51.0 0.0 3.8e-06 26.5 0.0 3.3 3 1 0 3 3 3 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.6 EPS34872.1 - 5.5e-06 26.4 0.0 1.1e-05 25.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EPS34872.1 - 0.0062 16.4 0.0 0.023 14.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 HAT_KAT11 PF08214.11 EPS34873.1 - 6.4e-105 351.3 0.0 1e-104 350.7 0.0 1.2 1 0 0 1 1 1 1 Histone acetylation protein DUF4452 PF14618.6 EPS34873.1 - 0.066 13.1 0.7 0.15 11.9 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4452) GDPD_2 PF13653.6 EPS34875.1 - 0.083 13.4 1.6 0.18 12.3 0.5 2.2 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family Hid1 PF12722.7 EPS34876.1 - 0 1067.1 0.0 0 1066.9 0.0 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.9 EPS34876.1 - 1.7e-98 330.7 0.0 2.1e-98 330.4 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein DASH_Spc19 PF08287.11 EPS34876.1 - 0.067 13.1 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Spc19 NPCC PF08058.11 EPS34877.1 - 1.3e-22 80.3 0.0 2.2e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore complex component AMP-binding PF00501.28 EPS34878.1 - 3.6e-09 35.7 0.1 6e-06 25.1 0.1 2.3 2 1 0 2 2 2 2 AMP-binding enzyme ATHILA PF03078.15 EPS34878.1 - 0.045 12.6 0.0 0.065 12.0 0.0 1.1 1 0 0 1 1 1 0 ATHILA ORF-1 family DNA_pol3_chi PF04364.13 EPS34879.1 - 0.11 12.7 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 DNA polymerase III chi subunit, HolC Ribosomal_L19 PF01245.20 EPS34880.1 - 2.8e-16 59.4 1.8 5.1e-16 58.6 1.8 1.4 1 1 0 1 1 1 1 Ribosomal protein L19 PriA_3primeBD PF17764.1 EPS34880.1 - 0.046 13.6 0.0 0.13 12.1 0.0 1.8 1 1 0 1 1 1 0 3′ DNA-binding domain (3′BD) PhaP_Bmeg PF09602.10 EPS34880.1 - 0.19 11.7 0.2 0.31 11.0 0.2 1.3 1 0 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Sulfotransfer_3 PF13469.6 EPS34881.1 - 0.007 16.8 0.0 0.016 15.6 0.0 1.7 1 1 0 1 1 1 1 Sulfotransferase family RasGEF_N_2 PF14663.6 EPS34881.1 - 0.031 14.7 0.3 0.2 12.1 0.1 2.1 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain ABC_tran PF00005.27 EPS34882.1 - 2.7e-49 167.2 0.1 4.4e-25 88.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EPS34882.1 - 8.4e-23 81.6 0.2 4.5e-05 23.4 0.0 4.4 3 1 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 EPS34882.1 - 6.2e-22 78.2 39.4 3.5e-14 52.7 20.5 2.8 2 1 0 2 2 2 2 ABC-2 family transporter protein SMC_N PF02463.19 EPS34882.1 - 1.1e-08 34.8 0.0 0.036 13.5 0.0 4.0 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EPS34882.1 - 1.8e-07 30.8 2.6 0.00044 19.9 0.8 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 EPS34882.1 - 6.7e-07 30.0 0.6 0.046 14.2 0.1 2.6 2 0 0 2 2 2 2 AAA domain DUF4162 PF13732.6 EPS34882.1 - 8.8e-05 23.2 0.0 0.0054 17.4 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4162) AAA_15 PF13175.6 EPS34882.1 - 0.00056 19.7 0.1 0.45 10.2 0.1 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_16 PF13191.6 EPS34882.1 - 0.0015 18.9 0.4 1.5 9.1 0.2 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EPS34882.1 - 0.002 18.1 5.0 1.3 8.9 0.1 3.3 4 0 0 4 4 3 2 RsgA GTPase AAA_27 PF13514.6 EPS34882.1 - 0.0034 17.0 0.4 0.51 9.9 0.1 2.3 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 EPS34882.1 - 0.01 15.5 0.9 1.3 8.7 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain SbcCD_C PF13558.6 EPS34882.1 - 0.013 15.7 0.3 19 5.6 0.1 3.6 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 EPS34882.1 - 0.016 14.9 4.7 1.8 8.2 0.0 3.2 4 0 0 4 4 4 0 AAA domain AAA_25 PF13481.6 EPS34882.1 - 0.075 12.6 1.4 12 5.5 0.1 2.9 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EPS34882.1 - 0.091 12.0 0.8 14 4.9 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.6 EPS34882.1 - 0.091 13.0 0.4 22 5.3 0.2 2.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EPS34882.1 - 0.12 12.7 1.1 22 5.4 0.2 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EPS34882.1 - 0.13 12.5 1.7 17 5.6 0.9 2.5 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EPS34882.1 - 0.23 12.0 0.3 27 5.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.16 EPS34883.1 - 1.9e-33 115.8 25.4 3e-33 115.2 25.4 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_4 PF06779.14 EPS34883.1 - 9.3e-05 21.9 13.9 0.00095 18.6 13.7 2.0 1 1 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB ABC2_membrane PF01061.24 EPS34884.1 - 2.5e-81 272.1 57.7 9.2e-42 142.8 15.9 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EPS34884.1 - 2.8e-34 118.6 1.2 2.7e-17 63.6 0.0 3.1 4 0 0 4 4 3 2 ABC transporter PDR_CDR PF06422.12 EPS34884.1 - 3.5e-21 74.9 10.1 1.9e-19 69.4 0.0 3.4 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 EPS34884.1 - 1.9e-14 54.0 0.1 5.4e-14 52.6 0.1 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 EPS34884.1 - 6.7e-09 35.3 36.8 4.8e-06 25.9 17.1 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 EPS34884.1 - 1.1e-05 25.4 0.0 0.19 11.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 EPS34884.1 - 1.5e-05 25.6 0.0 0.001 19.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EPS34884.1 - 5.2e-05 23.7 0.5 0.0089 16.4 0.1 3.3 3 0 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.6 EPS34884.1 - 5.9e-05 23.3 0.0 0.00086 19.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EPS34884.1 - 0.00014 21.8 0.0 0.00064 19.7 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EPS34884.1 - 0.0013 18.5 0.6 0.011 15.4 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.6 EPS34884.1 - 0.002 17.8 0.1 0.0099 15.5 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 EPS34884.1 - 0.0044 17.5 0.0 0.13 12.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 EPS34884.1 - 0.005 16.3 0.1 0.63 9.4 0.0 3.0 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.6 EPS34884.1 - 0.0077 16.5 0.0 0.078 13.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 EPS34884.1 - 0.05 13.2 0.6 0.21 11.2 0.2 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.6 EPS34884.1 - 0.11 12.8 0.5 0.61 10.4 0.1 2.5 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EPS34884.1 - 0.13 11.9 0.6 1.8 8.2 0.2 2.4 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EPS34884.1 - 0.14 12.1 0.5 7.3 6.5 0.3 2.4 2 0 0 2 2 2 0 NACHT domain DnaB_C PF03796.15 EPS34884.1 - 0.22 10.8 0.4 11 5.3 0.0 2.6 3 0 0 3 3 3 0 DnaB-like helicase C terminal domain AAA_23 PF13476.6 EPS34884.1 - 0.33 11.4 0.1 0.33 11.4 0.1 2.8 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.9 EPS34884.1 - 1 9.1 2.9 8.5 6.1 0.1 2.7 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation Opi1 PF08618.10 EPS34885.1 - 3.6e-45 155.0 10.4 4.8e-33 115.0 1.9 3.2 1 1 2 3 3 3 3 Transcription factor Opi1 DUF4726 PF15855.5 EPS34885.1 - 0.0035 17.5 0.7 0.011 15.9 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4726) TetR_C_34 PF17929.1 EPS34885.1 - 0.085 13.0 0.1 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain MCPVI PF02993.14 EPS34885.1 - 0.19 11.5 3.2 0.19 11.6 1.0 2.1 2 0 0 2 2 2 0 Minor capsid protein VI RdRP PF05183.12 EPS34886.1 - 1e-126 424.0 0.0 1.5e-126 423.5 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase AA_permease PF00324.21 EPS34887.1 - 1.1e-65 222.1 33.9 1.4e-65 221.8 33.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 EPS34887.1 - 7e-13 48.2 35.4 9.1e-13 47.8 35.4 1.1 1 0 0 1 1 1 1 Amino acid permease COX14 PF14880.6 EPS34887.1 - 4 7.4 7.1 12 5.8 1.8 3.5 3 0 0 3 3 3 0 Cytochrome oxidase c assembly NmrA PF05368.13 EPS34888.1 - 5.7e-28 98.1 0.0 7e-28 97.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EPS34888.1 - 4e-15 56.2 0.0 5.6e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EPS34888.1 - 0.00014 22.1 0.1 0.00024 21.3 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EPS34888.1 - 0.0036 16.8 0.0 0.029 13.8 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.24 EPS34888.1 - 0.0082 16.6 0.1 0.014 15.8 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EPS34888.1 - 0.0092 16.0 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 EPS34888.1 - 0.22 11.6 0.1 0.38 10.9 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus FERM_M PF00373.18 EPS34891.1 - 0.01 16.2 0.1 0.016 15.6 0.1 1.5 1 1 0 1 1 1 0 FERM central domain KfrA_N PF11740.8 EPS34891.1 - 0.029 15.0 0.3 0.064 13.9 0.3 1.6 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term DUF3089 PF11288.8 EPS34891.1 - 0.15 11.6 0.0 0.33 10.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) Fumarate_red_D PF02313.17 EPS34893.1 - 0.12 12.5 0.1 0.2 11.8 0.1 1.3 1 0 0 1 1 1 0 Fumarate reductase subunit D Voldacs PF03517.13 EPS34894.1 - 1.1e-27 96.9 1.7 1.1e-27 96.9 1.7 2.3 2 1 0 2 2 2 1 Regulator of volume decrease after cellular swelling Metallophos PF00149.28 EPS34896.1 - 6.7e-37 128.0 0.0 1.1e-36 127.3 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPT PF03151.16 EPS34898.1 - 3.5e-22 79.1 22.4 4.2e-22 78.8 22.4 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EPS34898.1 - 3.1e-06 27.4 38.6 0.0011 19.2 7.9 2.1 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EPS34898.1 - 0.0012 18.1 24.2 0.0022 17.2 24.2 1.5 1 1 0 1 1 1 1 UAA transporter family Glyco_transf_25 PF01755.17 EPS34900.1 - 8.3e-11 42.1 0.2 3.6e-07 30.3 0.2 2.5 2 1 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) DUF1996 PF09362.10 EPS34901.1 - 6.4e-83 278.3 0.6 9.4e-83 277.8 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Aldo_ket_red PF00248.21 EPS34902.1 - 2e-70 237.3 0.0 2.4e-70 237.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Phage_ABA_S PF18066.1 EPS34902.1 - 0.023 15.4 0.4 0.08 13.6 0.0 2.0 2 0 0 2 2 2 0 Phage ABA sandwich domain adh_short_C2 PF13561.6 EPS34903.1 - 2.8e-62 210.3 0.0 3.4e-62 210.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EPS34903.1 - 7.1e-52 175.7 0.2 8.8e-52 175.4 0.2 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EPS34903.1 - 5.6e-07 29.6 0.1 9.5e-07 28.9 0.1 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EPS34903.1 - 0.00057 19.4 0.2 0.001 18.6 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Fungal_trans_2 PF11951.8 EPS34904.1 - 2.6e-34 118.7 0.1 6.5e-34 117.4 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS34904.1 - 4.9e-09 36.2 7.9 8.5e-09 35.4 7.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease_2 PF13520.6 EPS34905.1 - 4.2e-42 144.5 46.7 5.6e-42 144.0 46.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EPS34905.1 - 7.1e-17 61.1 37.1 1e-16 60.7 37.1 1.1 1 0 0 1 1 1 1 Amino acid permease PNTB PF02233.16 EPS34906.1 - 2.3e-171 570.8 26.7 2.3e-171 570.8 26.7 2.0 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 EPS34906.1 - 4.1e-74 248.5 0.2 4.1e-74 248.5 0.2 2.3 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 EPS34906.1 - 1.5e-44 151.6 0.1 3.8e-44 150.3 0.1 1.8 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 EPS34906.1 - 1.7e-30 105.3 3.1 1.7e-30 105.3 3.1 5.4 5 1 1 6 6 6 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 EPS34906.1 - 0.0002 20.8 0.3 0.37 10.1 0.0 3.2 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPP_enzyme_M PF00205.22 EPS34906.1 - 0.0013 18.5 0.3 0.0049 16.6 0.3 2.1 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Pyr_redox_2 PF07992.14 EPS34906.1 - 0.024 13.9 0.1 0.061 12.6 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N PF00107.26 EPS34906.1 - 0.059 13.4 0.3 0.49 10.4 0.1 2.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase GIDA PF01134.22 EPS34906.1 - 0.069 12.2 0.1 0.13 11.3 0.1 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_8 PF13450.6 EPS34906.1 - 0.35 11.1 2.6 0.42 10.9 0.2 2.5 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pkinase PF00069.25 EPS34909.1 - 0.013 14.9 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain ELO PF01151.18 EPS34911.1 - 1.6e-61 208.0 24.9 1.9e-61 207.7 24.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family COX5A PF02284.16 EPS34912.1 - 4.7e-39 132.5 0.4 6.5e-39 132.1 0.4 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va LOH1CR12 PF10158.9 EPS34912.1 - 0.014 15.4 0.2 3.6 7.6 0.1 2.2 1 1 1 2 2 2 0 Tumour suppressor protein Glyco_transf_15 PF01793.16 EPS34913.1 - 1.6e-114 382.6 11.1 1.9e-114 382.3 11.1 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase GCP_N_terminal PF17681.1 EPS34914.1 - 3e-32 112.5 2.6 1.6e-31 110.1 0.2 2.4 3 0 0 3 3 3 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EPS34914.1 - 4.3e-19 69.1 0.3 4.3e-19 69.1 0.3 2.0 3 0 0 3 3 3 1 Gamma tubulin complex component C-terminal GCP5-Mod21 PF14609.6 EPS34914.1 - 1.1e-08 34.0 0.0 1.1e-08 34.0 0.0 1.6 2 0 0 2 2 2 1 gamma-Tubulin ring complex non-core subunit mod21 GATase_5 PF13507.6 EPS34915.1 - 4e-99 330.9 0.0 6.1e-99 330.3 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 EPS34915.1 - 5.9e-39 133.7 0.3 1.4e-24 87.0 0.2 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 EPS34915.1 - 1.2e-33 115.6 0.0 2.4e-33 114.5 0.0 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 EPS34915.1 - 3.1e-22 78.9 0.0 6.6e-22 77.8 0.0 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain AIRS PF00586.24 EPS34915.1 - 0.033 14.9 0.1 0.21 12.2 0.0 2.4 2 0 0 2 2 2 0 AIR synthase related protein, N-terminal domain MFS_1 PF07690.16 EPS34916.1 - 2.6e-39 135.1 30.7 2.6e-39 135.1 30.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EPS34916.1 - 1e-11 44.4 4.4 1e-11 44.4 4.4 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EPS34916.1 - 1e-07 30.8 1.8 1.7e-07 30.0 1.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2178 PF09946.9 EPS34916.1 - 0.01 16.0 3.2 0.14 12.3 0.4 2.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2178) Fungal_trans PF04082.18 EPS34917.1 - 5.3e-10 38.8 0.2 8.6e-10 38.1 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS34917.1 - 8.4e-06 25.8 11.6 1.6e-05 25.0 11.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAA_hydrolase PF01557.18 EPS34918.1 - 3e-51 174.2 0.0 4.8e-51 173.5 0.0 1.3 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 EPS34918.1 - 2.1e-16 60.0 0.0 5.4e-16 58.7 0.0 1.7 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal DJ-1_PfpI PF01965.24 EPS34919.1 - 5.3e-10 39.3 0.0 2.9e-09 36.9 0.0 1.9 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EPS34919.1 - 0.0048 16.6 0.0 0.0065 16.2 0.0 1.2 1 0 0 1 1 1 1 ThiJ/PfpI family-like DIT1_PvcA PF05141.12 EPS34920.1 - 1.3e-92 310.2 0.0 2e-92 309.6 0.0 1.3 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.16 EPS34920.1 - 2e-23 83.5 0.0 5.1e-23 82.2 0.0 1.7 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family RNase_H PF00075.24 EPS34921.1 - 1.1e-06 28.9 0.0 3.3e-06 27.3 0.0 1.8 2 0 0 2 2 2 1 RNase H Tau95 PF09734.9 EPS34924.1 - 2.5e-40 138.5 0.4 4.7e-40 137.6 0.4 1.5 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 EPS34924.1 - 2.3e-30 105.4 0.0 5.5e-30 104.2 0.0 1.7 1 1 0 1 1 1 1 Tau95 Triple barrel domain TFIIF_beta PF02270.15 EPS34924.1 - 0.077 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 TFIIF, beta subunit HTH domain B56 PF01603.20 EPS34925.1 - 4.6e-193 641.8 7.0 5.5e-193 641.6 7.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Sec7_N PF12783.7 EPS34925.1 - 0.0087 16.0 1.4 1.1 9.1 0.0 2.4 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Pol_alpha_B_N PF08418.10 EPS34925.1 - 0.5 10.3 4.2 1.1 9.1 4.2 1.6 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal FAT PF02259.23 EPS34926.1 - 1.7e-72 244.6 10.0 5.3e-72 242.9 10.0 2.0 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 EPS34926.1 - 3e-35 122.2 0.0 8.1e-35 120.8 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 EPS34926.1 - 2.3e-05 24.1 0.1 7e-05 22.6 0.1 1.9 1 0 0 1 1 1 1 FATC domain TPR_2 PF07719.17 EPS34926.1 - 0.37 11.0 4.6 1.6 9.1 0.4 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF572 PF04502.13 EPS34927.1 - 1.3e-68 232.1 11.2 1.5e-68 231.9 11.2 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-ACC PF17848.1 EPS34927.1 - 0.069 13.2 1.8 2.1 8.5 0.5 2.6 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Zn_ribbon_SprT PF17283.2 EPS34927.1 - 0.29 11.1 2.3 0.63 10.0 2.3 1.5 1 1 0 1 1 1 0 SprT-like zinc ribbon domain HU-CCDC81_bac_2 PF18175.1 EPS34927.1 - 2.2 8.2 6.5 12 5.8 0.1 2.4 2 0 0 2 2 2 0 CCDC81-like prokaryotic HU domain 2 TPR_1 PF00515.28 EPS34928.1 - 4.2e-30 102.3 4.1 0.00045 19.9 0.3 10.2 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_2 PF07719.17 EPS34928.1 - 2.8e-28 95.7 12.7 0.0032 17.5 0.0 10.3 10 0 0 10 10 10 6 Tetratricopeptide repeat ANAPC3 PF12895.7 EPS34928.1 - 4.5e-25 87.7 17.4 3.5e-21 75.2 1.9 5.5 5 0 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EPS34928.1 - 3.4e-20 72.3 16.9 0.00033 21.1 0.0 7.8 6 2 2 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 EPS34928.1 - 7.2e-18 64.7 21.1 2.2e-09 37.5 0.2 9.6 7 3 1 9 9 9 2 Tetratricopeptide repeat TPR_8 PF13181.6 EPS34928.1 - 2.6e-15 55.3 0.3 0.54 10.6 0.1 8.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 EPS34928.1 - 2.8e-15 55.7 17.8 1.4 9.9 0.2 9.8 7 2 2 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 EPS34928.1 - 9.5e-12 45.4 24.9 0.23 12.1 0.1 9.1 7 2 0 9 9 9 2 Tetratricopeptide repeat TPR_11 PF13414.6 EPS34928.1 - 1.7e-10 40.4 3.3 0.38 10.5 0.1 7.8 8 0 0 8 8 8 3 TPR repeat TPR_6 PF13174.6 EPS34928.1 - 7.5e-09 35.7 12.2 0.71 10.6 0.1 7.9 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 EPS34928.1 - 1.2e-07 31.3 26.2 0.00062 19.5 0.1 8.2 11 0 0 11 11 9 2 Tetratricopeptide repeat TPR_7 PF13176.6 EPS34928.1 - 1.4e-07 31.1 20.7 0.67 10.1 0.0 9.5 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_4 PF07721.14 EPS34928.1 - 2.7e-06 27.5 13.2 1.9 9.3 1.1 8.5 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EPS34928.1 - 4e-06 26.5 12.5 0.001 18.5 0.2 4.6 5 0 0 5 5 5 2 MalT-like TPR region TPR_17 PF13431.6 EPS34928.1 - 0.0003 21.0 5.5 5.1 7.7 0.0 7.2 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_21 PF09976.9 EPS34928.1 - 0.0015 18.3 3.3 14 5.4 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat-like domain DUF3856 PF12968.7 EPS34928.1 - 0.019 15.1 0.2 3.4 7.7 0.0 3.5 4 0 0 4 4 4 0 Domain of Unknown Function (DUF3856) SRP_TPR_like PF17004.5 EPS34928.1 - 0.07 13.2 0.2 1 9.4 0.0 2.9 2 1 0 2 2 2 0 Putative TPR-like repeat TPR_9 PF13371.6 EPS34928.1 - 1.7 8.9 17.7 29 4.9 0.1 6.5 5 3 1 6 6 6 0 Tetratricopeptide repeat Glyco_transf_90 PF05686.12 EPS34929.1 - 1.6e-26 93.2 0.2 2e-26 92.8 0.2 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 FeoC PF09012.10 EPS34929.1 - 0.086 12.9 0.3 0.34 11.0 0.2 1.9 2 0 0 2 2 2 0 FeoC like transcriptional regulator DUF2617 PF10936.8 EPS34929.1 - 0.096 12.8 0.1 0.25 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF2617 CVNH PF08881.10 EPS34930.1 - 1.7e-24 86.4 0.0 1.9e-24 86.2 0.0 1.0 1 0 0 1 1 1 1 CVNH domain NikR_C PF08753.11 EPS34930.1 - 0.061 13.5 0.0 0.096 12.9 0.0 1.3 1 0 0 1 1 1 0 NikR C terminal nickel binding domain MCM PF00493.23 EPS34931.1 - 7.1e-104 345.8 0.1 1.7e-103 344.6 0.0 1.6 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 EPS34931.1 - 2.2e-36 124.5 0.3 4.2e-36 123.6 0.3 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EPS34931.1 - 5.4e-29 100.4 1.8 1.4e-28 99.2 1.8 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EPS34931.1 - 1e-14 55.0 0.1 2.6e-14 53.6 0.1 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EPS34931.1 - 3.9e-06 26.4 0.0 0.00088 18.7 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EPS34931.1 - 5.7e-05 23.1 0.0 0.00011 22.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EPS34931.1 - 0.0005 19.9 0.0 0.0017 18.2 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EPS34931.1 - 0.059 13.1 0.0 1.4 8.6 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Imm35 PF15567.6 EPS34931.1 - 0.068 13.3 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 35 AAA PF00004.29 EPS34931.1 - 0.15 12.5 0.0 0.38 11.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Vps54 PF07928.12 EPS34932.1 - 1.2e-50 171.4 0.4 1.2e-50 171.4 0.4 2.8 3 0 0 3 3 3 1 Vps54-like protein DUF2451 PF10474.9 EPS34932.1 - 5.4e-06 26.4 0.1 2.2e-05 24.4 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Vps54_N PF10475.9 EPS34932.1 - 5e-05 22.7 1.9 5e-05 22.7 1.9 1.9 3 0 0 3 3 3 1 Vacuolar-sorting protein 54, of GARP complex FliJ PF02050.16 EPS34932.1 - 0.067 13.4 2.4 0.3 11.3 2.4 2.1 1 0 0 1 1 1 0 Flagellar FliJ protein Glycogen_syn PF05693.13 EPS34934.1 - 0 1146.3 0.0 0 1146.1 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_4 PF13439.6 EPS34934.1 - 4.3e-05 23.6 0.4 9.4e-05 22.5 0.4 1.7 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EPS34934.1 - 5.5e-05 23.7 0.1 0.00013 22.4 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.6 EPS34934.1 - 9.2e-05 22.9 0.0 0.016 15.6 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 EPS34934.1 - 0.00027 20.5 0.0 0.003 17.1 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 NMT1 PF09084.11 EPS34935.1 - 1.1e-76 257.6 0.0 1.7e-76 257.0 0.0 1.3 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.6 EPS34935.1 - 0.0021 17.8 0.1 0.21 11.3 0.0 3.0 3 1 0 3 3 3 1 NMT1-like family Mannosyl_trans3 PF11051.8 EPS34936.1 - 5.9e-56 189.8 0.0 7.1e-55 186.3 0.0 2.1 1 1 0 1 1 1 1 Mannosyltransferase putative polyprenyl_synt PF00348.17 EPS34937.1 - 1.3e-88 296.3 0.0 1.6e-88 296.0 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase RNase_H2-Ydr279 PF09468.10 EPS34937.1 - 0.0018 18.5 0.1 0.0051 17.0 0.1 1.7 2 0 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain DUF4457 PF14652.6 EPS34937.1 - 0.025 13.8 0.1 0.03 13.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4457) DUF2184 PF09950.9 EPS34937.1 - 0.079 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2184) ANAPC8 PF04049.13 EPS34938.1 - 3.8e-53 179.3 0.2 1.7e-52 177.2 0.0 2.1 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 EPS34938.1 - 9.5e-22 75.9 4.8 0.00077 19.2 0.0 7.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 EPS34938.1 - 4.3e-21 73.3 6.8 0.0017 18.4 0.0 7.9 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 EPS34938.1 - 1.8e-16 58.9 13.5 0.063 13.4 2.8 8.8 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.6 EPS34938.1 - 2.8e-12 46.4 20.5 0.029 15.2 0.0 9.0 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 EPS34938.1 - 6.3e-12 45.0 1.1 6e-06 25.8 0.0 4.4 2 2 2 4 4 4 2 TPR repeat ANAPC3 PF12895.7 EPS34938.1 - 2.1e-09 37.4 14.0 0.58 10.4 0.1 6.5 6 0 0 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EPS34938.1 - 1.4e-08 35.1 15.4 0.085 13.4 0.3 7.6 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 EPS34938.1 - 1.6e-07 31.8 18.8 0.0002 21.9 0.0 6.6 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 EPS34938.1 - 1.7e-07 31.4 9.0 0.021 15.1 2.4 5.9 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 EPS34938.1 - 2.1e-07 30.9 2.7 0.61 10.6 0.1 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 EPS34938.1 - 4.4e-06 26.8 2.8 0.00036 20.6 0.4 4.2 3 1 1 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EPS34938.1 - 1.8e-05 24.4 8.2 3 8.1 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 EPS34938.1 - 0.00025 21.5 24.3 3.8 8.3 0.4 9.8 10 1 0 10 10 10 1 Tetratricopeptide repeat TPR_15 PF13429.6 EPS34938.1 - 0.0011 18.3 7.1 0.0025 17.1 0.9 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat ChAPs PF09295.10 EPS34938.1 - 0.094 11.7 0.1 2.1 7.2 0.0 2.6 1 1 2 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.6 EPS34938.1 - 0.77 9.7 8.5 7.7 6.5 0.3 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat DNA_ligase_A_M PF01068.21 EPS34939.1 - 4e-25 88.7 0.0 6.9e-25 87.9 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EPS34939.1 - 6.5e-23 81.9 0.0 8.1e-22 78.4 0.0 2.3 2 0 0 2 2 2 1 DNA ligase N terminus DUF3449 PF11931.8 EPS34940.1 - 8.4e-75 250.6 1.1 1.2e-74 250.1 0.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 EPS34940.1 - 2.2e-26 92.2 1.7 5.1e-26 91.0 0.3 2.2 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 EPS34940.1 - 6.9e-15 54.6 0.8 1.9e-14 53.2 0.8 1.9 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-C2H2_jaz PF12171.8 EPS34940.1 - 6e-10 39.2 0.6 1.9e-08 34.4 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EPS34940.1 - 8.1e-08 32.4 0.5 7.3e-06 26.2 0.2 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP9_N PF16958.5 EPS34940.1 - 0.0018 18.3 7.6 0.0077 16.3 2.3 3.5 3 1 1 4 4 4 2 Pre-mRNA-splicing factor PRP9 N-terminus zf-C2H2_4 PF13894.6 EPS34940.1 - 0.0047 17.6 0.9 1.2 10.2 0.0 2.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_2 PF12756.7 EPS34940.1 - 0.0057 17.0 0.0 0.06 13.7 0.0 2.6 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 EPS34940.1 - 0.66 10.5 3.6 10 6.8 0.3 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type DEAD PF00270.29 EPS34941.1 - 5.7e-41 140.2 0.2 9.5e-41 139.5 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EPS34941.1 - 1.5e-33 115.4 0.1 5.2e-33 113.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 EPS34941.1 - 0.00095 18.9 0.1 0.0014 18.3 0.1 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EPS34941.1 - 0.0021 18.1 0.0 0.0044 17.0 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EPS34941.1 - 0.0039 17.5 0.1 0.043 14.1 0.1 2.3 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 EPS34941.1 - 0.05 13.0 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Flavi_DEAD PF07652.14 EPS34941.1 - 0.078 13.0 0.8 0.24 11.4 0.0 2.2 3 0 0 3 3 3 0 Flavivirus DEAD domain AAA_22 PF13401.6 EPS34941.1 - 0.1 12.9 0.9 0.42 10.9 0.9 1.9 1 1 0 1 1 1 0 AAA domain Beta-lactamase PF00144.24 EPS34942.1 - 2.5e-27 96.0 0.0 3.7e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase WD40 PF00400.32 EPS34943.1 - 4.3e-22 78.0 18.8 0.00034 21.3 0.5 7.1 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS34943.1 - 4.5e-14 52.5 5.4 0.03 14.6 0.2 5.2 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EPS34943.1 - 9.8e-07 27.6 0.2 0.0021 16.6 0.1 2.4 2 1 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.11 EPS34943.1 - 9.4e-05 22.4 0.6 0.12 12.3 0.1 3.3 1 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 EPS34943.1 - 0.00018 21.3 0.2 16 5.5 0.0 4.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat CLTH PF10607.9 EPS34943.1 - 0.0016 18.3 0.3 0.0026 17.7 0.3 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Utp8 PF10395.9 EPS34943.1 - 0.0048 15.5 0.1 0.008 14.7 0.1 1.3 1 0 0 1 1 1 1 Utp8 family DUF1668 PF07893.13 EPS34943.1 - 0.0053 16.2 0.2 0.76 9.1 0.0 2.5 1 1 0 2 2 2 2 Protein of unknown function (DUF1668) WD40_like PF17005.5 EPS34943.1 - 0.0084 15.5 0.2 0.83 8.9 0.0 2.2 2 0 0 2 2 2 1 WD40-like domain Nup160 PF11715.8 EPS34943.1 - 0.01 14.5 1.2 0.12 11.0 0.2 2.2 1 1 0 2 2 2 0 Nucleoporin Nup120/160 Frtz PF11768.8 EPS34943.1 - 0.015 13.7 0.3 0.15 10.3 0.0 2.2 1 1 2 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Ge1_WD40 PF16529.5 EPS34943.1 - 0.018 14.1 3.7 2.7 6.9 1.5 3.3 1 1 2 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF2236 PF09995.9 EPS34944.1 - 1.8e-29 103.5 0.0 3.4e-29 102.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) LPD11 PF18824.1 EPS34944.1 - 0.014 15.5 0.0 0.038 14.1 0.0 1.7 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 11 PEP_mutase PF13714.6 EPS34945.1 - 9.2e-64 215.2 1.3 1e-63 215.0 1.3 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Ribosomal_60s PF00428.19 EPS34945.1 - 0.32 11.6 2.1 0.91 10.1 0.1 2.7 3 1 1 4 4 4 0 60s Acidic ribosomal protein FAD_binding_3 PF01494.19 EPS34946.1 - 4e-21 75.6 0.0 9.8e-21 74.4 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 EPS34946.1 - 3.8e-10 39.9 0.3 3.2e-05 23.7 0.1 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EPS34946.1 - 1.1e-05 24.9 0.1 0.0022 17.3 0.0 2.1 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EPS34946.1 - 0.00011 22.3 0.0 0.00025 21.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 EPS34946.1 - 0.00014 20.8 0.5 0.014 14.3 0.1 2.6 2 1 1 3 3 3 2 Tryptophan halogenase GIDA PF01134.22 EPS34946.1 - 0.00018 20.7 0.0 0.00037 19.7 0.0 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 EPS34946.1 - 0.0003 21.3 0.0 0.061 13.9 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EPS34946.1 - 0.0029 16.9 0.0 0.006 15.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 EPS34946.1 - 0.0044 16.1 0.1 0.017 14.3 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.12 EPS34946.1 - 0.016 14.3 0.1 0.055 12.5 0.0 1.9 3 0 0 3 3 3 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EPS34946.1 - 0.022 14.1 0.1 0.097 11.9 0.1 1.9 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EPS34946.1 - 0.022 13.8 0.0 3.9 6.4 0.0 2.2 2 0 0 2 2 2 0 Squalene epoxidase NAD_binding_9 PF13454.6 EPS34946.1 - 0.066 13.2 0.0 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 EPS34946.1 - 0.092 12.0 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.14 EPS34946.1 - 0.1 11.3 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein MFS_1 PF07690.16 EPS34947.1 - 2.5e-50 171.4 22.1 8.8e-44 149.9 13.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EPS34947.1 - 5.1e-08 31.9 20.3 0.001 17.7 0.1 3.3 3 1 0 3 3 3 3 MFS/sugar transport protein OATP PF03137.20 EPS34947.1 - 1e-07 30.7 0.3 1e-07 30.7 0.3 3.1 2 1 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family LacY_symp PF01306.19 EPS34947.1 - 0.061 12.1 18.2 0.013 14.3 1.4 3.3 3 1 0 3 3 3 0 LacY proton/sugar symporter KRTDAP PF15200.6 EPS34948.1 - 0.026 14.3 0.2 0.057 13.2 0.2 1.5 1 0 0 1 1 1 0 Keratinocyte differentiation-associated Peptidase_S7 PF00949.21 EPS34948.1 - 0.038 13.8 0.0 0.093 12.5 0.0 1.6 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Trypsin_2 PF13365.6 EPS34948.1 - 0.075 13.9 1.6 0.83 10.5 1.6 2.5 1 1 0 1 1 1 0 Trypsin-like peptidase domain ATP-synt_ab PF00006.25 EPS34949.1 - 1.5e-108 361.3 0.0 2.2e-108 360.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 EPS34949.1 - 1.1e-45 154.4 0.0 2e-45 153.5 0.0 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 EPS34949.1 - 3e-16 59.7 0.7 5.6e-16 58.8 0.7 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.22 EPS34949.1 - 0.026 13.7 0.1 1.4 8.0 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Dynamin_M PF01031.20 EPS34950.1 - 1e-101 339.9 0.0 1.9e-101 339.1 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 EPS34950.1 - 7.3e-57 192.1 0.1 1.4e-56 191.1 0.1 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 EPS34950.1 - 6.8e-31 106.3 4.3 6.8e-31 106.3 4.3 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EPS34950.1 - 5.7e-05 23.2 0.4 0.00034 20.7 0.4 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.6 EPS34950.1 - 0.0081 15.9 1.3 1.5 8.4 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain DUF2226 PF09987.9 EPS34950.1 - 0.019 14.3 0.4 1 8.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2226) SdiA-regulated PF06977.11 EPS34950.1 - 0.032 13.5 0.0 0.058 12.6 0.0 1.3 1 0 0 1 1 1 0 SdiA-regulated CN_hydrolase PF00795.22 EPS34952.1 - 5.9e-34 117.6 0.0 6.8e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Glyco_hydro_16 PF00722.21 EPS34953.1 - 1.4e-08 34.4 0.1 2.3e-08 33.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 PH PF00169.29 EPS34954.1 - 1.1e-06 29.1 0.7 2.6e-06 27.9 0.7 1.5 1 0 0 1 1 1 1 PH domain RmlD_sub_bind PF04321.17 EPS34955.1 - 4.3e-56 190.1 0.0 5.3e-56 189.8 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EPS34955.1 - 2.3e-23 82.9 0.0 2.9e-23 82.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EPS34955.1 - 2.5e-12 46.5 0.5 2.7e-10 39.9 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 EPS34955.1 - 2.7e-11 43.2 0.3 1.9e-08 33.8 0.0 3.0 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 EPS34955.1 - 4.1e-11 42.9 0.2 1.7e-10 40.9 0.2 1.8 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EPS34955.1 - 1.2e-10 40.9 0.1 1.1e-09 37.8 0.1 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 EPS34955.1 - 0.0003 20.8 0.1 0.34 10.8 0.0 2.7 3 0 0 3 3 3 2 KR domain NAD_binding_10 PF13460.6 EPS34955.1 - 0.022 14.6 0.1 0.063 13.2 0.1 1.9 1 1 0 1 1 1 0 NAD(P)H-binding RPA_C PF08784.11 EPS34955.1 - 0.03 15.0 0.0 0.053 14.2 0.0 1.5 1 0 0 1 1 1 0 Replication protein A C terminal FAD-oxidase_C PF02913.19 EPS34956.1 - 3.9e-63 213.4 0.0 5.3e-63 213.0 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EPS34956.1 - 1.4e-37 128.5 0.4 3.3e-37 127.3 0.4 1.6 1 0 0 1 1 1 1 FAD binding domain Pkinase PF00069.25 EPS34957.1 - 2e-70 237.2 0.0 2.6e-70 236.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EPS34957.1 - 2.2e-47 161.5 0.0 3.1e-47 161.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EPS34957.1 - 0.00011 21.1 0.0 0.00024 20.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EPS34957.1 - 0.00026 20.4 0.1 0.0045 16.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like ABC1 PF03109.16 EPS34957.1 - 0.026 14.7 0.0 0.081 13.1 0.0 1.8 2 0 0 2 2 2 0 ABC1 family DUF4048 PF13257.6 EPS34958.1 - 3.6e-85 285.9 20.7 3.6e-85 285.9 20.7 3.5 4 0 0 4 4 4 1 Domain of unknown function (DUF4048) PI3K_1B_p101 PF10486.9 EPS34958.1 - 0.033 12.0 0.0 0.033 12.0 0.0 2.1 4 0 0 4 4 4 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Bap31_Bap29_C PF18035.1 EPS34958.1 - 0.038 14.0 1.8 0.081 12.9 1.8 1.6 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain Myb_DNA-bind_6 PF13921.6 EPS34958.1 - 0.049 13.9 0.1 0.15 12.3 0.1 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain Tim17 PF02466.19 EPS34959.1 - 2.8e-40 137.1 4.9 3.8e-40 136.7 4.9 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Cnd3 PF12719.7 EPS34960.1 - 2.6e-90 302.6 0.0 4e-88 295.4 0.0 2.7 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 EPS34960.1 - 6.4e-08 32.9 4.6 4.6e-05 23.7 0.1 4.2 2 1 1 3 3 3 2 HEAT repeats Adaptin_N PF01602.20 EPS34960.1 - 0.00048 18.8 0.4 0.052 12.1 0.1 2.5 3 0 0 3 3 3 2 Adaptin N terminal region HEAT PF02985.22 EPS34960.1 - 0.001 19.1 9.3 4.5 7.8 0.0 6.4 7 0 0 7 7 7 1 HEAT repeat Cnd1 PF12717.7 EPS34960.1 - 0.0067 16.5 0.6 0.23 11.5 0.1 3.4 3 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 DUF1885 PF08968.10 EPS34960.1 - 0.012 15.7 0.0 0.025 14.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1885) MMS19_N PF14500.6 EPS34960.1 - 0.033 13.8 0.3 0.18 11.3 0.1 2.4 3 0 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II RTP1_C1 PF10363.9 EPS34960.1 - 0.13 12.4 0.1 1.6 8.9 0.1 2.6 2 1 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF4760 PF15956.5 EPS34960.1 - 0.15 12.2 0.0 2.2 8.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4760) HEAT_EZ PF13513.6 EPS34960.1 - 0.26 11.8 4.2 23 5.6 0.0 4.7 4 1 1 5 5 5 0 HEAT-like repeat zf-RanBP PF00641.18 EPS34962.1 - 1.2e-20 72.5 9.1 7.7e-11 41.1 1.5 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 EPS34962.1 - 7e-08 32.2 0.0 1.9e-07 30.8 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.24 EPS34962.1 - 1.2e-05 25.9 0.0 1.8e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Exonuclease zf-ribbon_3 PF13248.6 EPS34962.1 - 0.21 11.1 2.4 2.5 7.6 0.3 2.7 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 EPS34962.1 - 0.32 11.0 4.3 2.6 8.2 0.3 2.4 2 0 0 2 2 2 0 Double zinc ribbon Proteasome PF00227.26 EPS34964.1 - 2.8e-56 190.0 0.1 3.8e-56 189.6 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EPS34964.1 - 8.5e-14 50.9 0.3 3e-13 49.2 0.1 2.0 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Terminase_5 PF06056.12 EPS34964.1 - 0.023 14.6 0.1 0.051 13.5 0.1 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) zf-CHY PF05495.12 EPS34965.1 - 3.4e-12 46.7 21.5 6.2e-12 45.8 21.5 1.4 1 0 0 1 1 1 1 CHY zinc finger RNA_POL_M_15KD PF02150.16 EPS34965.1 - 0.27 11.2 11.0 6.2 6.8 1.1 3.3 2 1 1 3 3 3 0 RNA polymerases M/15 Kd subunit HypA PF01155.19 EPS34965.1 - 1.2 9.2 12.7 3.6 7.7 12.6 1.8 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_9 PF14369.6 EPS34965.1 - 1.8 8.9 12.6 0.58 10.5 6.9 2.6 1 1 2 3 3 3 0 zinc-ribbon C1_4 PF07975.12 EPS34965.1 - 9.2 6.6 16.9 37 4.7 0.3 2.7 1 1 2 3 3 3 0 TFIIH C1-like domain Exo_endo_phos PF03372.23 EPS34966.1 - 1.7e-11 44.1 0.0 3.8e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PQQ_2 PF13360.6 EPS34966.1 - 0.004 16.8 0.5 0.57 9.7 0.1 2.5 1 1 1 2 2 2 2 PQQ-like domain WD40 PF00400.32 EPS34966.1 - 2.6 9.0 5.3 3.1 8.8 1.6 3.2 4 0 0 4 4 4 0 WD domain, G-beta repeat Pyridox_ox_2 PF12900.7 EPS34967.1 - 0.11 12.4 0.4 0.18 11.8 0.4 1.3 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase DAO PF01266.24 EPS34968.1 - 6e-31 108.3 0.0 1.2e-30 107.3 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EPS34968.1 - 6e-05 23.2 0.7 0.00063 19.9 0.2 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EPS34968.1 - 0.00076 19.5 0.4 0.014 15.4 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.14 EPS34968.1 - 0.001 18.4 0.0 0.004 16.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AvrLm4-7 PF18661.1 EPS34968.1 - 0.0025 18.8 0.4 0.0044 18.0 0.4 1.4 1 0 0 1 1 1 1 Avirulence Effector AvrLm4-7 Thi4 PF01946.17 EPS34968.1 - 0.0034 16.6 0.0 0.0056 15.9 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.24 EPS34968.1 - 0.005 16.2 0.1 0.01 15.2 0.0 1.5 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase CobT PF06213.12 EPS34969.1 - 0.026 13.9 10.8 0.025 14.0 10.8 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FAM176 PF14851.6 EPS34969.1 - 0.065 12.9 8.3 0.077 12.6 8.3 1.2 1 0 0 1 1 1 0 FAM176 family YqfQ PF14181.6 EPS34969.1 - 0.074 13.2 4.7 0.09 13.0 4.7 1.1 1 0 0 1 1 1 0 YqfQ-like protein PPP4R2 PF09184.11 EPS34969.1 - 0.086 12.4 12.2 0.081 12.5 12.2 1.0 1 0 0 1 1 1 0 PPP4R2 RNA_pol_3_Rpc31 PF11705.8 EPS34969.1 - 0.13 12.5 17.0 0.12 12.6 17.0 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CDC45 PF02724.14 EPS34969.1 - 0.14 10.4 9.9 0.13 10.5 9.9 1.0 1 0 0 1 1 1 0 CDC45-like protein SspB PF04386.13 EPS34969.1 - 0.15 12.0 4.1 0.15 11.9 4.1 1.1 1 0 0 1 1 1 0 Stringent starvation protein B AIF_C PF14721.6 EPS34969.1 - 0.18 12.2 0.7 0.18 12.2 0.7 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Connexin PF00029.19 EPS34969.1 - 0.2 11.4 1.5 0.2 11.4 1.5 1.1 1 0 0 1 1 1 0 Connexin TFB6 PF17110.5 EPS34969.1 - 0.22 11.3 4.3 0.21 11.3 4.3 1.1 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH eIF_4EBP PF05456.11 EPS34969.1 - 0.23 11.4 1.2 0.26 11.2 1.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) D123 PF07065.14 EPS34969.1 - 0.24 10.5 3.8 0.24 10.5 3.8 1.0 1 0 0 1 1 1 0 D123 RAB3GAP2_C PF14656.6 EPS34969.1 - 0.32 9.2 4.0 0.31 9.2 4.0 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus TRAP_alpha PF03896.16 EPS34969.1 - 0.5 9.5 8.3 0.47 9.6 8.3 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Presenilin PF01080.17 EPS34969.1 - 0.55 8.9 1.7 0.49 9.1 1.7 1.0 1 0 0 1 1 1 0 Presenilin NOA36 PF06524.12 EPS34969.1 - 1.3 8.3 15.9 1.3 8.3 15.9 1.0 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 EPS34969.1 - 1.3 9.5 15.6 1.8 9.0 15.6 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Usp PF00582.26 EPS34969.1 - 1.7 9.2 5.8 2 8.9 5.8 1.2 1 0 0 1 1 1 0 Universal stress protein family TFIIF_alpha PF05793.12 EPS34969.1 - 2 6.9 18.0 1.7 7.1 18.0 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Phage_Gp23 PF10669.9 EPS34969.1 - 2 8.8 9.5 2.5 8.5 9.5 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) DUF4820 PF16091.5 EPS34969.1 - 2.2 7.6 5.6 2.1 7.6 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) SDA1 PF05285.12 EPS34969.1 - 3.1 7.1 17.8 3.2 7.1 17.8 1.0 1 0 0 1 1 1 0 SDA1 Sporozoite_P67 PF05642.11 EPS34969.1 - 4.5 5.2 7.5 4.1 5.4 7.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Paf1 PF03985.13 EPS34969.1 - 7.6 5.4 22.6 8.1 5.3 22.6 1.0 1 0 0 1 1 1 0 Paf1 DUF3431 PF11913.8 EPS34971.1 - 1.4e-82 276.7 0.0 1.7e-82 276.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) F-box-like PF12937.7 EPS34972.1 - 4.9e-08 32.7 0.3 9.6e-08 31.8 0.3 1.5 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 EPS34972.1 - 0.082 13.4 0.2 5.4 7.6 0.2 3.2 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) F-box PF00646.33 EPS34972.1 - 0.14 12.1 0.2 0.58 10.1 0.2 2.1 1 0 0 1 1 1 0 F-box domain GFA PF04828.14 EPS34973.1 - 3.8e-10 40.0 4.1 7.4e-10 39.0 4.1 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme NPP1 PF05630.11 EPS34974.1 - 8.8e-06 26.0 2.6 7.7e-05 22.9 0.4 2.2 1 1 1 2 2 2 2 Necrosis inducing protein (NPP1) DAO PF01266.24 EPS34975.1 - 8.4e-52 176.9 0.1 9.7e-52 176.7 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EPS34975.1 - 1.8e-06 27.4 0.0 0.0015 17.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EPS34975.1 - 0.00071 18.8 0.2 0.088 11.9 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EPS34975.1 - 0.00082 19.6 1.1 0.0017 18.5 0.3 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EPS34975.1 - 0.0046 16.2 0.0 0.036 13.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase CNTF PF01110.17 EPS34975.1 - 0.0055 16.1 0.0 0.0096 15.3 0.0 1.3 1 0 0 1 1 1 1 Ciliary neurotrophic factor NAD_binding_9 PF13454.6 EPS34975.1 - 0.007 16.4 0.3 0.075 13.0 0.1 2.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.17 EPS34975.1 - 0.015 14.6 0.0 0.033 13.4 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 EPS34975.1 - 0.043 12.9 0.1 0.067 12.2 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.14 EPS34975.1 - 0.14 10.8 0.1 6.2 5.4 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein Chromate_transp PF02417.15 EPS34976.1 - 6e-59 198.7 31.7 3.5e-32 111.7 13.8 2.1 2 0 0 2 2 2 2 Chromate transporter UPF0047 PF01894.17 EPS34977.1 - 3.9e-37 126.9 0.0 4.4e-37 126.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 zf-CHCC PF10276.9 EPS34978.1 - 2.2e-17 62.8 0.9 3.7e-17 62.1 0.9 1.4 1 0 0 1 1 1 1 Zinc-finger domain DUF3246 PF11596.8 EPS34979.1 - 0.0038 16.7 0.1 0.0051 16.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) MPP6 PF10175.9 EPS34979.1 - 0.0057 17.2 1.8 0.0057 17.2 1.8 2.4 1 1 1 2 2 2 1 M-phase phosphoprotein 6 CDC45 PF02724.14 EPS34979.1 - 0.29 9.4 6.1 0.38 9.0 6.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Spt5_N PF11942.8 EPS34979.1 - 7.7 7.6 15.4 1.6 9.8 10.0 2.1 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal CoaE PF01121.20 EPS34980.1 - 7.6e-41 139.7 0.0 1.2e-40 139.1 0.0 1.2 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 EPS34980.1 - 0.013 16.1 0.3 0.37 11.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain 2TM PF13239.6 EPS34980.1 - 0.061 13.6 0.2 0.11 12.8 0.2 1.4 1 0 0 1 1 1 0 2TM domain DUF3431 PF11913.8 EPS34981.1 - 1.4e-89 299.6 0.2 1.9e-89 299.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Lipase_3 PF01764.25 EPS34982.1 - 1.7e-37 128.5 0.0 2.4e-37 128.0 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.16 EPS34982.1 - 2.9e-08 33.6 0.0 6.7e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Lipase 3 N-terminal region Abhydrolase_8 PF06259.12 EPS34982.1 - 0.00069 19.3 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase Abhydrolase_6 PF12697.7 EPS34982.1 - 0.006 17.2 0.1 0.0086 16.7 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPS34982.1 - 0.018 14.3 0.1 0.034 13.4 0.0 1.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF2974 PF11187.8 EPS34982.1 - 0.019 14.6 0.5 0.47 10.0 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2974) TPP_enzyme_N PF02776.18 EPS34982.1 - 0.084 12.5 0.0 3.9 7.1 0.0 2.2 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain NUDIX_2 PF13869.6 EPS34983.1 - 1.7e-81 272.3 0.0 2.1e-81 272.1 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Peptidase_M16_M PF16187.5 EPS34984.1 - 4.2e-95 318.2 0.1 6.8e-95 317.5 0.1 1.4 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 EPS34984.1 - 2.1e-31 109.4 0.0 4e-19 69.3 0.0 3.4 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EPS34984.1 - 2.6e-30 105.4 5.4 4e-21 75.6 0.4 3.5 3 1 1 4 4 4 2 Insulinase (Peptidase family M16) DUF3810 PF12725.7 EPS34984.1 - 0.079 12.3 0.0 4.8 6.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) RVP_2 PF08284.11 EPS34984.1 - 0.16 11.7 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 Retroviral aspartyl protease Bys1 PF04681.12 EPS34985.1 - 3.7e-10 40.0 0.3 4.3e-10 39.7 0.3 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Arb2 PF09757.9 EPS34986.1 - 3.6e-102 340.9 0.4 4.7e-102 340.5 0.4 1.2 1 0 0 1 1 1 1 Arb2 domain Hist_deacetyl PF00850.19 EPS34986.1 - 1.8e-85 287.1 0.0 3.2e-85 286.3 0.0 1.4 1 0 0 1 1 1 1 Histone deacetylase domain Gp_dh_C PF02800.20 EPS34987.1 - 1e-72 242.9 0.1 1.6e-72 242.3 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EPS34987.1 - 6.8e-38 129.1 0.1 1.8e-37 127.7 0.1 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 EPS34987.1 - 0.056 13.6 0.2 0.37 10.9 0.0 2.3 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus Ribosomal_S8e PF01201.22 EPS34987.1 - 0.077 13.2 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S8e TTC5_OB PF16669.5 EPS34987.1 - 0.08 12.6 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat protein 5 OB fold domain 2-Hacid_dh_C PF02826.19 EPS34987.1 - 0.12 11.7 0.2 0.35 10.2 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pho88 PF10032.9 EPS34988.1 - 1.8e-80 268.5 0.3 2e-80 268.3 0.3 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Histone PF00125.24 EPS34989.1 - 7.3e-17 62.0 0.0 9.8e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EPS34989.1 - 9.9e-12 44.4 0.0 2.1e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EPS34989.1 - 3.4e-05 24.0 0.0 4.8e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone R3H PF01424.22 EPS34991.1 - 1.3e-11 44.3 0.0 2.6e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.22 EPS34991.1 - 4.4e-06 26.4 0.1 9.9e-06 25.3 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUZ-C PF12901.7 EPS34991.1 - 0.00017 21.5 2.9 0.00069 19.6 2.9 2.1 1 0 0 1 1 1 1 SUZ-C motif CAS_C PF12026.8 EPS34991.1 - 0.23 11.5 0.8 0.36 10.9 0.8 1.2 1 0 0 1 1 1 0 Crk-Associated Substrate C-terminal domain Aldo_ket_red PF00248.21 EPS34995.1 - 2.3e-13 50.0 0.0 5.2e-13 48.8 0.0 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family XkdW PF09636.10 EPS34995.1 - 0.061 13.4 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 XkdW protein HSF_DNA-bind PF00447.17 EPS34996.1 - 3e-28 98.3 0.3 5.8e-28 97.4 0.3 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.22 EPS34996.1 - 0.064 13.7 0.0 0.14 12.7 0.0 1.5 1 0 0 1 1 1 0 Ets-domain DUF4695 PF15766.5 EPS34996.1 - 0.096 12.9 0.9 0.4 10.9 0.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4695) Tmemb_cc2 PF10267.9 EPS34996.1 - 0.66 9.1 8.5 0.028 13.6 2.4 1.8 2 1 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein IATP PF04568.12 EPS34996.1 - 7.6 7.0 6.2 23 5.5 0.1 3.7 4 0 0 4 4 4 0 Mitochondrial ATPase inhibitor, IATP Pro_isomerase PF00160.21 EPS34997.1 - 1.8e-39 135.6 0.0 3.7e-39 134.5 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4604 PF15377.6 EPS34997.1 - 0.0001 22.8 0.1 0.0001 22.8 0.1 3.5 2 1 1 3 3 3 1 Domain of unknown function (DUF4604) ORC_WH_C PF18137.1 EPS34997.1 - 0.011 15.9 1.6 0.011 15.9 1.6 2.5 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal Cytochrom_B558a PF05038.13 EPS34997.1 - 4.2 6.9 5.0 8 6.0 5.0 1.4 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Clr5 PF14420.6 EPS34998.1 - 3.8e-07 30.2 0.0 7.6e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Clr5 domain HTH_Tnp_Tc3_2 PF01498.18 EPS34998.1 - 1.3e-05 25.4 0.9 0.0049 17.1 0.3 2.2 2 0 0 2 2 2 2 Transposase HTH_12 PF08461.10 EPS34998.1 - 0.0004 20.3 2.0 0.074 13.0 0.1 2.2 2 0 0 2 2 2 2 Ribonuclease R winged-helix domain HTH_21 PF13276.6 EPS34998.1 - 0.004 17.3 0.8 0.18 12.0 0.1 2.4 2 1 0 2 2 2 1 HTH-like domain HTH_32 PF13565.6 EPS34998.1 - 0.0087 16.7 1.7 0.36 11.5 0.1 2.2 1 1 1 2 2 2 1 Homeodomain-like domain Sigma54_DBD PF04552.13 EPS34998.1 - 0.012 15.3 0.7 0.023 14.4 0.7 1.4 1 1 0 1 1 1 0 Sigma-54, DNA binding domain Nif11 PF07862.11 EPS34998.1 - 0.04 14.2 0.0 0.059 13.7 0.0 1.4 1 0 0 1 1 1 0 Nif11 domain DUF5587 PF17825.1 EPS34998.1 - 0.2 8.9 0.0 0.23 8.7 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5587) His_Phos_2 PF00328.22 EPS34999.1 - 1.1e-05 25.0 0.1 0.00011 21.6 0.0 2.1 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 2) PDGLE PF13190.6 EPS34999.1 - 0.083 12.8 0.5 0.4 10.6 0.3 2.1 2 0 0 2 2 2 0 PDGLE domain AAA PF00004.29 EPS35000.1 - 2.6e-16 60.2 0.0 4.7e-16 59.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 EPS35000.1 - 1e-15 57.9 0.0 3.8e-15 56.1 0.0 2.0 3 0 0 3 3 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 EPS35000.1 - 1.4e-12 47.7 0.1 5.3e-12 45.8 0.1 2.0 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 EPS35000.1 - 1.4e-08 34.9 0.0 2.4e-08 34.1 0.0 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 EPS35000.1 - 2.5e-07 30.9 0.1 1e-06 29.0 0.0 2.2 2 1 0 2 2 1 1 AAA C-terminal domain AAA_30 PF13604.6 EPS35000.1 - 6.6e-07 29.2 0.1 2.2e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EPS35000.1 - 9.4e-07 28.9 0.3 6.2e-05 22.9 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 EPS35000.1 - 1.6e-06 28.5 0.1 5e-05 23.6 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EPS35000.1 - 2.8e-06 27.8 0.1 1.9e-05 25.1 0.1 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 EPS35000.1 - 1.6e-05 24.8 0.0 2.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 EPS35000.1 - 2.4e-05 24.2 0.0 4.2e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_19 PF13245.6 EPS35000.1 - 4.3e-05 23.9 0.1 0.00011 22.5 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EPS35000.1 - 5.1e-05 23.3 0.6 0.00025 21.1 0.2 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 EPS35000.1 - 5.5e-05 22.4 0.0 0.0001 21.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 EPS35000.1 - 8.9e-05 22.3 0.0 0.00027 20.7 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 EPS35000.1 - 0.00013 21.8 0.1 0.0029 17.5 0.1 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 EPS35000.1 - 0.00049 20.1 0.0 0.048 13.7 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_14 PF13173.6 EPS35000.1 - 0.00073 19.6 0.0 0.002 18.1 0.0 1.7 1 1 1 2 2 2 1 AAA domain Sigma54_activat PF00158.26 EPS35000.1 - 0.0012 18.6 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain DEAD PF00270.29 EPS35000.1 - 0.0017 18.1 0.1 0.025 14.3 0.0 2.3 1 1 1 2 2 2 1 DEAD/DEAH box helicase PhoH PF02562.16 EPS35000.1 - 0.0024 17.3 0.0 0.49 9.8 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein TniB PF05621.11 EPS35000.1 - 0.0038 16.7 0.1 0.028 13.8 0.1 2.2 1 1 0 1 1 1 1 Bacterial TniB protein AAA_28 PF13521.6 EPS35000.1 - 0.011 16.0 0.0 0.021 15.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EPS35000.1 - 0.013 14.8 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.22 EPS35000.1 - 0.014 15.8 0.0 0.033 14.6 0.0 1.7 1 1 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 EPS35000.1 - 0.014 14.9 0.0 0.032 13.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_18 PF13238.6 EPS35000.1 - 0.017 15.7 0.0 0.029 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EPS35000.1 - 0.021 14.2 0.2 0.15 11.4 0.1 2.4 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EPS35000.1 - 0.032 13.8 0.1 0.12 11.9 0.0 1.9 1 1 1 2 2 2 0 AAA domain ATPase_2 PF01637.18 EPS35000.1 - 0.039 13.9 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TK PF00265.18 EPS35000.1 - 0.04 13.8 0.0 0.076 12.9 0.0 1.5 1 0 0 1 1 1 0 Thymidine kinase ABC_tran PF00005.27 EPS35000.1 - 0.085 13.4 0.0 0.15 12.5 0.0 1.5 1 1 0 1 1 1 0 ABC transporter SRP54 PF00448.22 EPS35000.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain IstB_IS21 PF01695.17 EPS35000.1 - 0.11 12.2 0.0 0.67 9.7 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein TIP49 PF06068.13 EPS35000.1 - 0.13 11.4 0.0 0.29 10.3 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain NACHT PF05729.12 EPS35000.1 - 0.14 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain P21-Arc PF04062.14 EPS35001.1 - 2.2e-73 246.0 0.0 2.5e-73 245.8 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Gcd10p PF04189.13 EPS35002.1 - 4.8e-121 403.5 0.0 7.7e-121 402.8 0.0 1.3 1 0 0 1 1 1 1 Gcd10p family 3-PAP PF12578.8 EPS35002.1 - 0.0039 16.9 0.0 0.012 15.3 0.0 1.8 1 0 0 1 1 1 1 Myotubularin-associated protein MINDY_DUB PF04424.13 EPS35003.1 - 1.9e-20 73.1 0.0 3.3e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 MINDY deubiquitinase DUF5007 PF16398.5 EPS35003.1 - 0.074 12.7 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5007) Cellulase PF00150.18 EPS35004.1 - 3.9e-37 128.2 0.5 7.2e-37 127.3 0.5 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_X2 PF03442.14 EPS35004.1 - 4.4e-26 90.8 2.5 2.7e-23 81.9 1.0 3.5 3 0 0 3 3 3 2 Carbohydrate binding domain X2 CBM_1 PF00734.18 EPS35004.1 - 1.3e-10 41.0 15.5 1.3e-10 41.0 15.5 2.0 2 0 0 2 2 2 1 Fungal cellulose binding domain RSN1_7TM PF02714.15 EPS35005.1 - 7.7e-87 291.1 21.4 7.7e-87 291.1 21.4 1.9 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EPS35005.1 - 1.7e-41 141.6 1.6 1.7e-41 141.6 1.6 2.5 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EPS35005.1 - 1.4e-32 113.3 0.1 3.2e-32 112.2 0.0 1.6 2 0 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter PHM7_ext PF12621.8 EPS35005.1 - 6.7e-27 93.5 0.1 1.6e-26 92.3 0.1 1.6 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter kleA_kleC PF17383.2 EPS35005.1 - 0.082 13.2 3.7 0.11 12.8 0.2 2.6 3 0 0 3 3 3 0 Uncharacterized KorC regulated protein A Abhydrolase_1 PF00561.20 EPS35006.1 - 7.8e-14 51.9 0.1 3.2e-13 49.9 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EPS35006.1 - 4.7e-09 37.2 0.1 6.4e-09 36.7 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EPS35006.1 - 0.00015 21.1 0.0 0.00042 19.7 0.0 1.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 BAAT_C PF08840.11 EPS35006.1 - 0.016 15.1 0.0 3.3 7.6 0.0 2.3 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.20 EPS35006.1 - 0.022 14.4 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DLH PF01738.18 EPS35006.1 - 0.05 13.1 0.0 0.15 11.6 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family PIG-P PF08510.12 EPS35007.1 - 1.1e-54 183.5 1.9 1.6e-54 183.0 1.9 1.3 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 EPS35007.1 - 0.46 10.8 8.3 0.75 10.1 8.3 1.2 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) XPA_C PF05181.12 EPS35008.1 - 3.8e-26 90.8 2.6 7.8e-26 89.8 2.6 1.6 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 EPS35008.1 - 0.027 14.5 5.4 0.027 14.5 5.4 2.1 2 0 0 2 2 2 0 XPA protein N-terminal zf-AD PF07776.15 EPS35008.1 - 0.62 10.3 4.8 4.8 7.5 4.9 2.3 1 1 1 2 2 2 0 Zinc-finger associated domain (zf-AD) YhfH PF14149.6 EPS35008.1 - 2.9 7.9 11.0 0.7 9.9 0.3 2.6 2 1 0 2 2 2 0 YhfH-like protein Striatin PF08232.12 EPS35010.1 - 9.7e-45 152.9 10.7 9.7e-45 152.9 10.7 2.9 3 0 0 3 3 3 1 Striatin family WD40 PF00400.32 EPS35010.1 - 5.2e-27 93.6 19.1 1.9e-05 25.3 0.3 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EPS35010.1 - 0.00034 20.8 0.0 3 8.2 0.0 4.6 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EPS35010.1 - 0.022 14.6 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EPS35010.1 - 0.14 11.0 0.1 0.58 9.1 0.0 2.1 3 1 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Blt1 PF12754.7 EPS35011.1 - 2e-66 222.9 0.1 3.1e-66 222.3 0.1 1.3 1 0 0 1 1 1 1 Blt1 N-terminal domain Blt1_C PF17183.4 EPS35011.1 - 1.1e-23 82.6 0.1 2.1e-23 81.6 0.1 1.5 1 0 0 1 1 1 1 Get5 carboxyl domain Methyltr_RsmB-F PF01189.17 EPS35012.1 - 6.3e-72 241.4 0.0 1.2e-71 240.6 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 EPS35012.1 - 1.2e-07 32.1 0.0 3.4e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 EPS35012.1 - 0.0016 18.6 0.0 0.0032 17.6 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.19 EPS35012.1 - 0.045 13.5 0.0 0.089 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MORN PF02493.20 EPS35013.1 - 1.9e-15 55.7 21.6 0.00035 20.3 0.2 4.6 4 0 0 4 4 4 4 MORN repeat UCH PF00443.29 EPS35013.1 - 1.5e-12 47.6 0.0 2.3e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-C3HC4_3 PF13920.6 EPS35013.1 - 4.5e-11 42.4 15.6 7.2e-11 41.8 15.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) USP7_ICP0_bdg PF12436.8 EPS35013.1 - 1.2e-08 34.6 0.0 3.1e-08 33.2 0.0 1.6 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.6 EPS35013.1 - 0.0015 18.2 0.0 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Prok-RING_4 PF14447.6 EPS35013.1 - 0.017 14.9 15.6 0.033 14.0 15.6 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EPS35013.1 - 2.8 8.0 16.6 5.5 7.0 16.6 1.5 1 0 0 1 1 1 0 zinc-RING finger domain DS PF01916.17 EPS35014.1 - 3.3e-127 423.7 0.0 3.8e-127 423.5 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase CHRD PF07452.12 EPS35015.1 - 0.095 13.7 1.4 0.15 13.0 1.1 1.4 1 1 0 1 1 1 0 CHRD domain Myb_DNA-binding PF00249.31 EPS35016.1 - 1.4e-12 47.6 0.0 5.4e-07 29.7 0.0 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EPS35016.1 - 0.0022 17.8 0.1 0.0022 17.8 0.1 2.5 3 0 0 3 3 3 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 EPS35016.1 - 0.035 14.4 0.2 2.8 8.3 0.1 2.5 2 0 0 2 2 2 0 Myb-like DNA-binding domain LAP1C PF05609.12 EPS35016.1 - 2.7 7.0 9.1 7.8 5.5 9.1 1.7 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Cation_efflux PF01545.21 EPS35017.1 - 6.1e-20 71.8 10.7 7.7e-20 71.5 10.7 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EPS35017.1 - 7.3e-08 32.4 0.0 1.5e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter DUF2721 PF11026.8 EPS35017.1 - 1.7 8.6 11.0 2.2 8.2 0.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) p450 PF00067.22 EPS35019.1 - 1.7e-67 228.2 0.0 1.9e-67 228.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.18 EPS35020.1 - 4.2e-14 52.2 0.0 7.9e-14 51.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 EPS35020.1 - 4.8e-09 36.2 12.4 8.7e-09 35.4 12.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_12 PF13424.6 EPS35020.1 - 0.062 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1524 PF07510.11 EPS35021.1 - 1e-09 38.4 0.0 1.3e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.6 EPS35021.1 - 0.2 11.6 0.3 0.49 10.3 0.3 1.7 1 1 0 1 1 1 0 HNH endonuclease Transp_cyt_pur PF02133.15 EPS35022.1 - 3.7e-46 157.8 34.2 4.2e-46 157.6 34.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin ArabFuran-catal PF09206.11 EPS35023.1 - 1.4e-154 514.1 10.9 2.4e-154 513.3 10.9 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.13 EPS35023.1 - 3.6e-58 195.5 2.2 6.2e-58 194.8 2.2 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) domain HATPase_c PF02518.26 EPS35025.1 - 3.6e-19 69.3 0.0 7.2e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EPS35025.1 - 2.5e-17 63.1 0.0 4.8e-17 62.1 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EPS35025.1 - 1.4e-13 50.6 0.4 4.3e-12 45.9 0.0 2.6 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.6 EPS35025.1 - 0.023 15.0 0.1 0.13 12.6 0.0 2.4 2 0 0 2 2 2 0 GAF domain CAP_N PF01213.19 EPS35025.1 - 0.54 9.7 10.4 0.24 10.8 4.4 2.7 3 0 0 3 3 3 0 Adenylate cyclase associated (CAP) N terminal FAD_binding_4 PF01565.23 EPS35026.1 - 3.1e-33 114.4 7.8 5.1e-33 113.7 7.8 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EPS35026.1 - 1.7e-10 40.8 0.1 3.7e-10 39.7 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like Aa_trans PF01490.18 EPS35027.1 - 1.8e-40 138.9 34.9 2.3e-40 138.6 34.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Sugar_tr PF00083.24 EPS35029.1 - 1.3e-68 231.9 21.0 1.5e-68 231.7 21.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EPS35029.1 - 5.1e-09 35.5 25.9 5.1e-09 35.5 25.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EPS35029.1 - 0.004 16.1 2.3 0.004 16.1 2.3 2.4 2 0 0 2 2 2 1 MFS_1 like family Glyco_hydro_43 PF04616.14 EPS35030.1 - 3.1e-35 121.9 1.4 3.9e-35 121.6 1.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 M-factor PF03855.13 EPS35030.1 - 0.45 10.7 0.1 0.45 10.7 0.1 2.4 3 0 0 3 3 3 0 M-factor RTA1 PF04479.13 EPS35032.1 - 8.5e-21 74.5 2.9 9.9e-21 74.3 2.9 1.0 1 0 0 1 1 1 1 RTA1 like protein DUF1440 PF07274.12 EPS35032.1 - 0.052 13.9 0.0 0.067 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1440) DUF5635 PF18685.1 EPS35032.1 - 0.064 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5635) FAD_binding_1 PF00667.20 EPS35033.1 - 6.1e-23 81.6 0.0 7.9e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EPS35033.1 - 0.015 15.9 0.0 0.049 14.3 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain FAD_binding_3 PF01494.19 EPS35034.1 - 2.6e-19 69.7 0.6 7.5e-18 64.9 0.6 2.6 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 EPS35034.1 - 0.0031 16.6 0.0 0.28 10.2 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase NAD_binding_8 PF13450.6 EPS35034.1 - 0.0068 16.6 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EPS35034.1 - 0.0092 15.6 0.0 0.089 12.3 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EPS35034.1 - 0.018 15.6 0.0 1.4 9.5 0.0 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EPS35034.1 - 0.091 12.0 0.2 1.6 7.9 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase polyprenyl_synt PF00348.17 EPS35036.1 - 1.7e-65 220.6 0.0 2e-65 220.4 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase adh_short PF00106.25 EPS35037.1 - 1.1e-44 152.3 1.4 1.1e-44 152.3 1.4 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EPS35037.1 - 1.6e-44 152.3 1.7 2.8e-44 151.4 1.7 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EPS35037.1 - 2.5e-06 27.5 2.3 2.1e-05 24.5 2.3 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EPS35037.1 - 0.0027 17.2 0.0 0.0038 16.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DFP PF04127.15 EPS35037.1 - 0.0093 15.8 0.5 0.013 15.3 0.5 1.2 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein ADH_zinc_N PF00107.26 EPS35037.1 - 0.03 14.3 0.2 0.055 13.5 0.2 1.5 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.8 EPS35037.1 - 0.082 12.7 0.4 0.2 11.4 0.4 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase p450 PF00067.22 EPS35038.1 - 1.5e-28 99.8 0.0 2.5e-28 99.1 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EPS35039.1 - 4e-27 95.1 0.0 5.2e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 UbiA PF01040.18 EPS35040.1 - 1.3e-32 113.1 13.4 1.4e-31 109.8 13.4 2.1 1 1 0 1 1 1 1 UbiA prenyltransferase family ketoacyl-synt PF00109.26 EPS35041.1 - 2.2e-73 247.0 0.0 3.7e-73 246.2 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EPS35041.1 - 4.9e-37 128.1 0.2 1e-36 127.0 0.2 1.5 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.6 EPS35041.1 - 6.5e-34 117.5 0.0 1.2e-33 116.7 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 EPS35041.1 - 3.2e-31 107.8 0.3 8.4e-31 106.4 0.3 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EPS35041.1 - 1.6e-17 64.0 0.0 4.6e-17 62.5 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 EPS35041.1 - 9.3e-08 32.1 0.0 2.1e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EPS35041.1 - 1.7e-07 31.8 0.0 5.5e-07 30.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EPS35041.1 - 1.2e-06 28.7 0.0 4.5e-06 26.9 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.6 EPS35041.1 - 0.00042 20.2 0.0 0.0018 18.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EPS35041.1 - 0.00066 20.3 0.0 0.0044 17.7 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EPS35041.1 - 0.0012 19.6 0.0 0.0061 17.3 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 EPS35041.1 - 0.0017 17.8 0.0 0.0041 16.5 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain SAT PF16073.5 EPS35041.1 - 0.0056 16.4 0.1 0.025 14.3 0.1 2.0 1 1 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis Ubie_methyltran PF01209.18 EPS35041.1 - 0.0069 15.7 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family KR PF08659.10 EPS35041.1 - 0.028 14.3 0.0 0.13 12.1 0.0 2.1 1 1 0 1 1 1 0 KR domain AMP-binding PF00501.28 EPS35042.1 - 1.7e-62 211.4 0.0 2.3e-62 211.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EPS35042.1 - 3.3e-08 34.4 0.1 8.7e-08 33.0 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain QRPTase_C PF01729.19 EPS35042.1 - 0.1 12.4 0.0 0.44 10.3 0.0 1.9 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain p450 PF00067.22 EPS35043.1 - 1e-33 116.8 0.0 1.3e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PhyH PF05721.13 EPS35044.1 - 1.1e-27 97.7 0.0 1.5e-27 97.3 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 EPS35044.1 - 0.071 11.9 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) p450 PF00067.22 EPS35045.1 - 7.9e-71 239.2 0.0 1e-70 238.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_71 PF03659.14 EPS35046.1 - 9.7e-135 449.2 5.8 9.7e-135 449.2 5.8 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 71 OTOS PF15182.6 EPS35046.1 - 0.27 11.2 2.3 0.59 10.1 0.0 2.8 3 0 0 3 3 3 0 Otospiralin # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Penicillium_oxalicum_114-2-pde_v1.0/GCA_000346795.1_pde_v1.0_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Penicillium_oxalicum_114-2-pde_v1.0/GCA_000346795.1_pde_v1.0_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Penicillium_oxalicum_114-2-pde_v1.0/GCA_000346795.1_pde_v1.0_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Penicillium_oxalicum_114-2-pde_v1.0/GCA_000346795.1_pde_v1.0_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 02:50:17 2019 # [ok]