# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- ChpXY PF10216.4 EPS25070.1 - 0.1 11.4 0.2 0.16 10.8 0.1 1.2 1 0 0 1 1 1 0 CO2 hydration protein (ChpXY) PHO4 PF01384.15 EPS25071.1 - 7.4e-111 369.9 10.8 8.9e-111 369.6 7.5 1.1 1 0 0 1 1 1 1 Phosphate transporter family GFA PF04828.9 EPS25072.1 - 1.1e-10 41.2 0.9 2.3e-10 40.2 0.6 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme fn3_3 PF14686.1 EPS25073.1 - 1.2e-11 44.6 0.0 4e-11 42.8 0.0 2.0 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CBM-like PF14683.1 EPS25073.1 - 1.7e-09 37.5 0.1 5.5e-09 35.8 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III CarboxypepD_reg PF13620.1 EPS25073.1 - 0.003 17.5 0.1 0.0097 15.9 0.0 1.8 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Peptidase_S10 PF00450.17 EPS25074.1 - 9.8e-90 301.6 0.1 1.3e-89 301.2 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Acetyltransf_3 PF13302.1 EPS25075.1 - 4.1e-33 114.5 0.0 4.8e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPS25075.1 - 0.001 19.0 0.0 0.0045 16.9 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPS25075.1 - 0.075 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Phage_antitermQ PF06530.7 EPS25075.1 - 0.13 11.7 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Phage antitermination protein Q CRAL_TRIO PF00650.15 EPS25076.1 - 1.4e-45 154.6 0.0 2.6e-45 153.7 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EPS25076.1 - 9.9e-13 48.0 0.0 2.6e-12 46.6 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EPS25076.1 - 2.4e-12 46.9 0.0 3.7e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DHQ_synthase PF01761.15 EPS25077.1 - 9.5e-53 178.7 0.0 1.5e-52 178.1 0.0 1.2 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.1 EPS25077.1 - 1.7e-13 50.4 0.0 2.6e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Methyltransf_3 PF01596.12 EPS25078.1 - 4.4e-17 61.8 0.0 5.9e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EPS25078.1 - 2e-10 41.4 0.0 3.1e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 EPS25078.1 - 0.0013 18.1 0.0 0.0029 16.9 0.0 1.4 1 1 0 1 1 1 1 Cephalosporin hydroxylase ATP-grasp_4 PF13535.1 EPS25079.1 - 9.6e-10 38.4 0.0 1.6e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EPS25079.1 - 4.5e-05 22.3 0.0 0.00019 20.2 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon MFS_1 PF07690.11 EPS25080.1 - 7.7e-21 74.1 39.3 9.3e-16 57.4 13.7 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS25080.1 - 1.1e-19 70.3 24.7 2.9e-19 69.0 17.1 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter FAD_binding_4 PF01565.18 EPS25082.1 - 2.3e-24 85.4 0.6 7.4e-23 80.5 0.2 2.4 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EPS25082.1 - 0.0088 15.9 0.0 0.023 14.5 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like DUF4488 PF14869.1 EPS25082.1 - 0.035 13.6 0.0 0.082 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4488) CBM_1 PF00734.13 EPS25083.1 - 1.6e-13 50.0 13.1 1.6e-13 50.0 9.1 2.6 3 0 0 3 3 3 1 Fungal cellulose binding domain Glyco_hydro_30 PF02055.11 EPS25083.1 - 2.7e-13 48.9 2.6 2.2e-08 32.7 0.8 3.2 3 1 0 3 3 3 2 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 EPS25083.1 - 2.4e-11 43.2 1.2 1.5e-08 33.9 0.0 2.8 1 1 1 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydro_43 PF04616.9 EPS25084.1 - 2.7e-40 138.2 4.5 4e-40 137.7 3.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_1 PF00734.13 EPS25084.1 - 4.7e-11 42.1 12.6 1.9e-10 40.2 8.8 2.2 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_62 PF03664.8 EPS25085.1 - 5.5e-134 445.4 7.0 6.8e-134 445.1 4.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 CBM_1 PF00734.13 EPS25085.1 - 4.3e-12 45.4 13.3 1.6e-11 43.6 9.2 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain Fungal_trans_2 PF11951.3 EPS25086.1 - 3.8e-10 38.9 0.3 5.2e-10 38.4 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS25086.1 - 0.63 10.0 9.7 1.4 8.8 6.7 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Arylesterase PF01731.15 EPS25087.1 - 0.1 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Arylesterase Ppx-GppA PF02541.11 EPS25088.1 - 9.5e-41 139.8 0.0 2.2e-40 138.6 0.0 1.5 1 1 0 1 1 1 1 Ppx/GppA phosphatase family Hydrophobin PF01185.13 EPS25090.1 - 2.9e-10 40.4 9.2 4.2e-10 39.9 6.4 1.3 1 0 0 1 1 1 1 Fungal hydrophobin DUF2574 PF10836.3 EPS25090.1 - 0.0052 16.4 2.1 0.011 15.3 0.3 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2574) AMP-binding PF00501.23 EPS25091.1 - 2.3e-101 339.2 0.0 2.7e-101 338.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPS25091.1 - 8.6e-12 45.8 0.0 1.8e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pyr_redox PF00070.22 EPS25092.1 - 7e-16 58.4 0.0 9.4e-14 51.5 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPS25092.1 - 9e-12 45.2 0.1 3.1e-06 27.1 0.0 3.4 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPS25092.1 - 1.1e-05 25.5 0.0 0.039 14.0 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EPS25092.1 - 0.0044 15.9 0.0 0.0094 14.8 0.0 1.5 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 EPS25092.1 - 0.0045 15.9 0.0 0.0076 15.2 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EPS25092.1 - 0.019 13.8 6.9 0.053 12.4 0.2 3.0 4 0 0 4 4 4 0 FAD dependent oxidoreductase DUF4523 PF15023.1 EPS25094.1 - 0.15 11.5 0.0 0.16 11.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) GST_C PF00043.20 EPS25095.1 - 8.9e-11 41.6 0.0 1.3e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EPS25095.1 - 1.7e-10 40.9 0.0 3e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EPS25095.1 - 4.7e-09 36.6 0.1 8.1e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EPS25095.1 - 5.1e-09 36.2 0.0 9.1e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EPS25095.1 - 2.4e-08 33.7 0.0 5.1e-08 32.6 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EPS25095.1 - 4.3e-06 26.6 0.0 7e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glyco_hydro_52 PF03512.8 EPS25095.1 - 0.048 12.2 0.0 0.056 12.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 52 GPW_gp25 PF04965.9 EPS25095.1 - 0.14 11.7 0.0 1.4 8.4 0.0 2.5 2 1 1 3 3 3 0 Gene 25-like lysozyme GMC_oxred_N PF00732.14 EPS25096.1 - 2.2e-48 164.9 0.5 3.1e-48 164.4 0.4 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EPS25096.1 - 1.3e-32 113.0 0.1 1e-31 110.1 0.0 2.3 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 EPS25096.1 - 1.1e-07 31.1 6.3 5.4e-07 28.8 4.3 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPS25096.1 - 4.5e-06 25.7 1.8 6.5e-06 25.2 1.2 1.4 1 1 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 EPS25096.1 - 9e-06 24.9 0.0 1.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EPS25096.1 - 3.5e-05 23.7 1.3 0.00011 22.1 0.3 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EPS25096.1 - 5.1e-05 23.2 0.2 0.00014 21.8 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPS25096.1 - 9.5e-05 21.5 0.1 0.00021 20.4 0.1 1.5 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 EPS25096.1 - 0.007 15.4 0.4 0.015 14.3 0.3 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EPS25096.1 - 0.015 13.8 0.1 0.029 12.8 0.1 1.5 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 EPS25096.1 - 0.11 11.4 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.13 EPS25096.1 - 0.13 11.8 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EPS25096.1 - 0.17 10.7 0.1 0.5 9.1 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A BTB_2 PF02214.17 EPS25097.1 - 9.3e-08 32.1 0.4 0.0003 20.9 0.1 2.4 2 0 0 2 2 2 2 BTB/POZ domain P_proprotein PF01483.15 EPS25097.1 - 0.065 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Proprotein convertase P-domain Nol1_Nop2_Fmu PF01189.12 EPS25098.1 - 2.3e-10 40.3 0.0 8.3e-06 25.3 0.0 2.8 2 1 0 2 2 2 2 NOL1/NOP2/sun family Acetyltransf_1 PF00583.19 EPS25099.1 - 1.3e-10 41.1 0.0 4.3e-10 39.4 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPS25099.1 - 6.1e-05 23.1 0.0 0.00023 21.2 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EPS25099.1 - 8.6e-05 22.3 0.0 0.00018 21.3 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_5 PF13444.1 EPS25099.1 - 0.0015 19.0 0.0 0.015 15.8 0.0 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPS25099.1 - 0.014 15.2 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.1 EPS25099.1 - 0.02 14.2 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Acetyltransf_10 PF13673.1 EPS25099.1 - 0.036 14.1 0.0 0.088 12.9 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPS25099.1 - 0.037 13.7 0.0 0.091 12.5 0.0 1.6 2 0 0 2 2 2 0 FR47-like protein FYVE PF01363.16 EPS25101.1 - 1.9e-15 56.5 7.4 2.8e-15 55.9 5.1 1.3 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.16 EPS25101.1 - 0.011 15.5 1.8 0.027 14.3 1.2 1.6 1 0 0 1 1 1 0 IBR domain zf-AN1 PF01428.11 EPS25101.1 - 0.38 10.6 10.8 0.84 9.5 7.5 1.5 1 0 0 1 1 1 0 AN1-like Zinc finger 2-Hacid_dh_C PF02826.14 EPS25104.1 - 1.6e-53 180.4 0.0 2.3e-53 179.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EPS25104.1 - 3.3e-28 97.7 0.0 3.9e-28 97.5 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AlaDh_PNT_C PF01262.16 EPS25104.1 - 0.00038 20.0 0.3 0.056 13.0 0.2 2.2 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.16 EPS25104.1 - 0.0032 17.3 0.1 0.02 14.7 0.0 2.0 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.10 EPS25104.1 - 0.0071 16.2 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.1 EPS25104.1 - 0.11 12.8 0.0 2.7 8.3 0.0 2.4 2 0 0 2 2 2 0 XdhC Rossmann domain Glycos_transf_1 PF00534.15 EPS25105.1 - 9.5e-37 126.0 0.0 1.3e-36 125.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EPS25105.1 - 6.1e-15 55.5 0.0 1.7e-14 54.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EPS25105.1 - 3.7e-10 40.1 0.0 3.7e-10 40.1 0.0 2.5 2 1 1 3 3 3 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EPS25105.1 - 1.2e-09 38.3 0.0 2.5e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EPS25105.1 - 0.00042 20.0 0.0 0.00088 19.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 ECH PF00378.15 EPS25107.1 - 3.4e-39 134.4 0.0 4.3e-39 134.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 EPS25107.1 - 0.009 16.1 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region GST_N PF02798.15 EPS25108.1 - 1.7e-11 44.1 0.0 3.7e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EPS25108.1 - 4.6e-11 42.7 0.0 9.2e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EPS25108.1 - 1.3e-09 37.9 0.0 2.4e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EPS25108.1 - 4.7e-06 26.4 0.0 1.2e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EPS25108.1 - 5.4e-06 26.3 0.0 8.4e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EPS25108.1 - 1.6e-05 25.3 0.0 3e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NDUF_B4 PF07225.7 EPS25109.1 - 1.9e-05 24.4 0.0 2.1e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) DUF3649 PF12365.3 EPS25109.1 - 0.012 15.0 2.5 0.017 14.5 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3649) SAP18 PF06487.7 EPS25110.1 - 1.2e-44 151.0 0.0 1.4e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Prp18 PF02840.10 EPS25111.1 - 4.8e-54 182.1 0.0 4.8e-54 182.1 0.0 2.2 2 1 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 EPS25111.1 - 3.2e-10 39.0 5.5 3.2e-10 39.0 3.8 2.8 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like Ycf1 PF05758.7 EPS25111.1 - 0.16 9.6 9.5 0.16 9.6 6.6 1.1 1 0 0 1 1 1 0 Ycf1 CDC27 PF09507.5 EPS25111.1 - 0.35 10.0 33.4 0.54 9.4 23.1 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 MIP-T3 PF10243.4 EPS25111.1 - 0.79 8.1 31.9 1 7.7 22.1 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SOBP PF15279.1 EPS25111.1 - 3.7 7.8 6.4 6.3 7.0 4.5 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein Presenilin PF01080.12 EPS25111.1 - 9 4.9 10.3 14 4.4 7.1 1.2 1 0 0 1 1 1 0 Presenilin Polysacc_deac_1 PF01522.16 EPS25112.1 - 4.4e-18 65.1 0.0 6e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_2 PF04748.8 EPS25112.1 - 0.088 11.8 0.0 0.18 10.7 0.0 1.7 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase Pyr_redox_3 PF13738.1 EPS25113.1 - 7.1e-06 26.2 0.0 4.8e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EPS25113.1 - 0.13 11.1 0.1 2.3 7.0 0.0 2.7 3 1 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Arf PF00025.16 EPS25114.1 - 8.2e-40 135.8 0.0 1.7e-26 92.5 0.0 2.3 2 1 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.15 EPS25114.1 - 8.7e-15 54.3 0.0 4e-08 32.3 0.0 2.3 2 1 0 2 2 2 2 G-protein alpha subunit Miro PF08477.8 EPS25114.1 - 1e-07 32.4 0.0 1.2e-06 29.0 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 EPS25114.1 - 2.9e-07 29.8 0.0 3.6e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EPS25114.1 - 1.5e-06 27.6 0.0 0.00059 19.2 0.0 2.6 2 1 0 2 2 2 2 Ras family SRPRB PF09439.5 EPS25114.1 - 2.2e-06 26.9 0.0 1.5e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EPS25114.1 - 1.1e-05 25.3 0.0 1.8e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EPS25114.1 - 0.00025 20.5 0.0 0.0073 15.7 0.0 2.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EPS25114.1 - 0.065 12.5 0.1 0.15 11.3 0.1 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B PIGA PF08288.7 EPS25116.1 - 6.6e-46 154.6 3.7 7.1e-46 154.5 0.8 2.1 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 EPS25116.1 - 3.6e-29 101.3 0.0 5.4e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EPS25116.1 - 4.4e-15 55.8 0.5 8.5e-15 54.9 0.3 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 EPS25116.1 - 6.3e-15 55.5 0.0 1.1e-14 54.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EPS25116.1 - 2.9e-13 50.2 0.0 5.4e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.1 EPS25116.1 - 0.00034 20.4 0.4 0.00065 19.5 0.3 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 EPS25116.1 - 0.00099 19.3 0.0 0.0089 16.2 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 DEAD PF00270.24 EPS25117.1 - 3.1e-34 117.8 0.0 4.6e-16 58.7 0.0 3.1 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EPS25117.1 - 4.5e-18 64.8 0.2 1.2e-17 63.5 0.2 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPS25117.1 - 3.4e-07 30.2 1.1 7e-06 25.9 0.0 2.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Nop14 PF04147.7 EPS25117.1 - 0.00024 19.2 10.7 0.00024 19.2 7.4 2.1 2 0 0 2 2 2 1 Nop14-like family CDC45 PF02724.9 EPS25117.1 - 6.2 4.7 38.3 0.011 13.8 7.3 2.5 2 0 0 2 2 2 0 CDC45-like protein Glyco_hydro_3 PF00933.16 EPS25118.1 - 1.3e-72 244.2 0.0 2e-72 243.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EPS25118.1 - 1.4e-52 178.5 0.2 2e-52 178.0 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EPS25118.1 - 2e-07 30.8 0.0 3.9e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DDR PF08841.5 EPS25118.1 - 0.25 10.1 0.0 0.43 9.3 0.0 1.3 1 0 0 1 1 1 0 Diol dehydratase reactivase ATPase-like domain Glyco_hydro_76 PF03663.9 EPS25120.1 - 2.4e-142 474.7 10.1 3e-142 474.4 7.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Fungal_trans PF04082.13 EPS25121.1 - 6e-17 61.3 0.0 1.1e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS25121.1 - 2.4e-10 40.1 11.3 4.1e-10 39.3 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TCTP PF00838.12 EPS25122.1 - 6.6e-43 146.5 0.3 7.5e-43 146.3 0.2 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein DUF4252 PF14060.1 EPS25122.1 - 0.058 12.9 0.1 0.081 12.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) FA_hydroxylase PF04116.8 EPS25123.1 - 1.2e-17 64.3 12.5 1.7e-17 63.8 7.5 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily MOSC PF03473.12 EPS25125.1 - 6.2e-16 58.0 0.1 1.5e-15 56.8 0.0 1.7 2 0 0 2 2 2 1 MOSC domain Fer2 PF00111.22 EPS25125.1 - 1.6e-12 47.0 0.9 3.5e-12 45.9 0.3 1.8 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.16 EPS25125.1 - 5.1e-06 27.0 0.0 2.2e-05 25.0 0.0 2.2 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EPS25125.1 - 0.00089 19.1 0.0 0.002 18.0 0.0 1.7 1 0 0 1 1 1 1 Ferric reductase NAD binding domain 3-alpha PF03475.9 EPS25125.1 - 0.043 13.5 0.0 0.11 12.1 0.0 1.8 1 0 0 1 1 1 0 3-alpha domain DUF1469 PF07332.6 EPS25127.1 - 0.018 14.7 1.8 0.033 13.9 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) SRP19 PF01922.12 EPS25128.1 - 4.3e-30 104.1 0.0 6.4e-30 103.5 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein Aminotran_3 PF00202.16 EPS25129.1 - 6.5e-88 294.8 0.0 7.7e-88 294.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III CPSF73-100_C PF11718.3 EPS25130.1 - 2e-74 249.5 0.0 4.8e-74 248.3 0.0 1.6 1 1 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 EPS25130.1 - 3.6e-32 110.9 0.0 6.9e-32 110.0 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 EPS25130.1 - 3.7e-18 65.8 0.0 3.7e-18 65.8 0.0 2.0 3 0 0 3 3 3 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EPS25130.1 - 2.7e-11 43.4 0.2 6.2e-11 42.2 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 EPS25130.1 - 3.4e-07 29.9 0.2 6.7e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 EPS25130.1 - 0.00033 20.3 0.1 0.00097 18.8 0.0 1.8 1 0 0 1 1 1 1 Beta-lactamase superfamily domain TAF4 PF05236.9 EPS25131.1 - 1.2e-18 67.3 0.0 1.6e-05 24.3 0.7 3.3 3 1 0 3 3 3 3 Transcription initiation factor TFIID component TAF4 family Pkinase PF00069.20 EPS25132.1 - 7.8e-55 185.8 0.0 1.3e-54 185.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS25132.1 - 2.4e-19 69.4 0.0 7.9e-19 67.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase DUF2975 PF11188.3 EPS25133.1 - 0.13 11.9 6.2 0.16 11.7 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) Amidase PF01425.16 EPS25134.1 - 6.5e-80 269.1 0.9 4.3e-78 263.1 0.6 2.6 1 1 0 1 1 1 1 Amidase Mtc PF03820.12 EPS25135.1 - 3.5e-104 347.7 0.2 1.8e-103 345.4 0.2 1.8 1 1 0 1 1 1 1 Tricarboxylate carrier PHD PF00628.24 EPS25136.1 - 2e-08 33.7 8.2 3.3e-08 33.0 5.7 1.3 1 0 0 1 1 1 1 PHD-finger DUF2293 PF10056.4 EPS25138.1 - 1.4e-32 111.5 0.1 2.9e-32 110.4 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) AlphaC_N PF08829.5 EPS25138.1 - 0.075 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Alpha C protein N terminal Gly_transf_sug PF04488.10 EPS25139.1 - 2.6e-11 43.7 0.0 6e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EPS25139.1 - 2.9e-05 22.7 0.1 0.0024 16.4 0.0 2.1 2 0 0 2 2 2 2 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.7 EPS25139.1 - 0.13 11.4 0.1 0.37 9.9 0.0 1.7 2 0 0 2 2 2 0 Capsular polysaccharide synthesis protein TruD PF01142.13 EPS25140.1 - 4.8e-51 173.5 0.1 3e-48 164.3 0.0 3.3 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) SKG6 PF08693.5 EPS25141.1 - 9.9e-05 21.5 1.8 0.00027 20.2 1.3 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 EPS25141.1 - 0.00035 20.1 0.0 0.00063 19.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.1 EPS25141.1 - 0.058 13.0 0.0 0.31 10.7 0.0 2.2 2 0 0 2 2 2 0 TMEM154 protein family ELO PF01151.13 EPS25144.1 - 1e-86 290.3 4.9 1.2e-86 290.0 3.4 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Glyco_hydro_35 PF01301.14 EPS25145.1 - 2.8e-78 263.4 2.0 8.7e-78 261.8 1.4 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 EPS25145.1 - 3.3e-66 222.1 0.5 7.7e-66 220.9 0.1 1.8 2 0 0 2 2 2 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 EPS25145.1 - 1.4e-48 163.7 13.9 4.5e-25 88.0 1.0 3.3 3 1 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 EPS25145.1 - 1e-27 95.3 0.2 2.2e-27 94.2 0.2 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Cellulase PF00150.13 EPS25145.1 - 5.4e-05 22.5 0.4 0.00011 21.5 0.3 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) ELL PF10390.4 EPS25148.1 - 0.079 12.1 0.0 0.079 12.1 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL AMP-binding PF00501.23 EPS25150.1 - 4.3e-43 147.2 0.0 5.8e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPS25150.1 - 7.5e-06 26.8 0.0 1.7e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Sulfotransfer_1 PF00685.22 EPS25151.1 - 2.6e-50 171.1 0.1 1.3e-49 168.8 0.1 1.8 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 EPS25151.1 - 2.6e-07 31.6 1.2 4.7e-07 30.8 0.8 1.4 1 0 0 1 1 1 1 Sulfotransferase family Sulphotransf PF09037.5 EPS25151.1 - 0.00026 20.5 0.1 0.089 12.2 0.0 2.6 3 0 0 3 3 3 2 Stf0 sulphotransferase Hexapep PF00132.19 EPS25152.1 - 3.7e-08 32.5 7.0 0.00038 19.8 0.4 3.1 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EPS25152.1 - 0.00024 21.2 0.0 0.00046 20.3 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.18 EPS25152.1 - 0.00026 20.3 0.0 0.0004 19.7 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Spt20 PF12090.3 EPS25154.1 - 5.7e-48 162.6 3.1 5.7e-48 162.6 2.2 4.6 3 3 1 4 4 4 1 Spt20 family Guanylate_kin PF00625.16 EPS25155.1 - 0.024 14.0 0.9 0.037 13.4 0.3 1.4 1 1 0 1 1 1 0 Guanylate kinase zf-C2H2 PF00096.21 EPS25156.1 - 5.5e-08 32.7 12.4 0.00071 19.7 2.7 3.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EPS25156.1 - 1.4e-05 25.1 4.3 1.4e-05 25.1 3.0 3.6 3 1 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EPS25156.1 - 5.2e-05 23.2 10.6 0.0035 17.5 1.0 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger Mitoc_L55 PF09776.4 EPS25156.1 - 0.026 14.1 0.2 0.043 13.3 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L55 DegQ PF08181.6 EPS25157.1 - 0.086 12.5 0.2 0.12 12.1 0.2 1.2 1 0 0 1 1 1 0 DegQ (SacQ) family MFS_1 PF07690.11 EPS25160.1 - 7.5e-17 61.0 34.2 1.6e-09 37.0 1.4 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EPS25160.1 - 0.00078 17.6 0.1 0.00078 17.6 0.1 1.6 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Ribonuclease_T2 PF00445.13 EPS25161.1 - 1.7e-43 148.4 0.4 2.5e-43 147.8 0.3 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family BCNT PF07572.7 EPS25162.1 - 9.3e-29 99.2 1.0 2.2e-28 97.9 0.7 1.7 1 0 0 1 1 1 1 Bucentaur or craniofacial development Bap31 PF05529.7 EPS25162.1 - 0.45 9.9 1.8 2 7.8 1.2 2.0 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like CDC45 PF02724.9 EPS25162.1 - 1.7 6.5 9.9 2.3 6.1 6.8 1.2 1 0 0 1 1 1 0 CDC45-like protein TrkH PF02386.11 EPS25165.1 - 1e-59 201.9 10.9 1e-56 192.0 2.5 2.3 2 0 0 2 2 2 2 Cation transport protein VirB3 PF05101.8 EPS25165.1 - 5.8 6.9 7.3 6.7 6.7 0.1 3.6 3 0 0 3 3 3 0 Type IV secretory pathway, VirB3-like protein F-box PF00646.28 EPS25166.1 - 0.0017 17.9 0.3 0.005 16.4 0.2 1.8 1 0 0 1 1 1 1 F-box domain Vezatin PF12632.2 EPS25166.1 - 0.08 12.0 0.7 0.12 11.3 0.4 1.5 1 1 0 1 1 1 0 Mysoin-binding motif of peroxisomes Amidohydro_4 PF13147.1 EPS25167.1 - 2.4e-13 50.7 0.1 3e-13 50.4 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_2 PF04909.9 EPS25167.1 - 4.4e-08 33.0 0.0 7.4e-08 32.2 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase LysR_substrate PF03466.15 EPS25167.1 - 0.026 13.6 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 LysR substrate binding domain Amidohydro_1 PF01979.15 EPS25167.1 - 0.034 13.8 0.1 0.12 12.0 0.1 2.0 1 1 0 1 1 1 0 Amidohydrolase family Mis12 PF05859.7 EPS25168.1 - 6.8e-43 145.9 0.0 1.2e-42 145.1 0.0 1.4 1 0 0 1 1 1 1 Mis12 protein TMF_DNA_bd PF12329.3 EPS25168.1 - 0.077 12.8 0.5 0.51 10.1 0.1 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding CENP-X PF09415.5 EPS25170.1 - 1.1e-28 98.8 0.1 2.1e-28 97.9 0.0 1.5 1 0 0 1 1 1 1 CENP-S associating Centromere protein X CBFD_NFYB_HMF PF00808.18 EPS25170.1 - 0.0052 16.8 0.7 0.0092 16.0 0.1 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ndc1_Nup PF09531.5 EPS25170.1 - 0.013 13.9 6.6 0.017 13.6 4.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2441 PF10386.4 EPS25170.1 - 0.097 12.6 0.1 0.14 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2441) Herpes_UL32 PF06070.6 EPS25170.1 - 0.37 9.2 12.3 0.41 9.0 8.5 1.0 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 DUF566 PF04484.7 EPS25170.1 - 8.1 5.8 12.6 9.7 5.5 8.7 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Macro PF01661.16 EPS25171.1 - 2.2e-05 24.3 0.0 2.8e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Macro domain DUF504 PF04457.7 EPS25172.1 - 3.6e-11 43.0 0.3 6.9e-11 42.1 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF504) MIF PF01187.13 EPS25172.1 - 3.3e-10 40.0 0.0 5.9e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Dus PF01207.12 EPS25173.1 - 6.2e-58 196.0 0.0 1.1e-57 195.2 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) WD40 PF00400.27 EPS25174.1 - 2.5e-05 23.9 2.7 0.4 10.6 0.0 5.0 4 1 0 4 4 4 3 WD domain, G-beta repeat Ribosomal_S25 PF03297.10 EPS25175.1 - 3e-39 133.3 5.0 3.2e-39 133.1 3.4 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_DeoR PF08220.7 EPS25175.1 - 0.018 14.5 0.3 0.026 14.0 0.2 1.2 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain HTH_11 PF08279.7 EPS25175.1 - 0.026 14.1 0.2 0.036 13.7 0.1 1.3 1 0 0 1 1 1 0 HTH domain MarR_2 PF12802.2 EPS25175.1 - 0.028 14.0 0.1 0.036 13.7 0.1 1.2 1 0 0 1 1 1 0 MarR family DDRGK PF09756.4 EPS25175.1 - 0.045 13.1 0.8 0.06 12.7 0.5 1.2 1 0 0 1 1 1 0 DDRGK domain FeoC PF09012.5 EPS25175.1 - 0.048 13.3 0.7 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 FeoC like transcriptional regulator Cyt-b5 PF00173.23 EPS25176.1 - 7.6e-08 32.0 0.0 1.1e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Gtr1_RagA PF04670.7 EPS25177.1 - 2.3e-70 236.3 0.1 4.5e-70 235.3 0.0 1.5 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EPS25177.1 - 6.9e-05 22.1 0.0 0.00014 21.1 0.0 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EPS25177.1 - 0.0028 18.1 0.0 0.0071 16.8 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EPS25177.1 - 0.024 13.8 0.0 0.04 13.1 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 EPS25177.1 - 0.062 13.2 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EPS25178.1 - 4e-48 163.2 5.8 9.7e-46 155.4 4.1 2.2 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EPS25178.1 - 1.2e-20 73.0 0.1 9.5e-16 57.2 0.0 3.0 3 0 0 3 3 3 2 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.9 EPS25178.1 - 0.003 17.2 0.1 0.0074 15.9 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EPS25178.1 - 0.0046 16.8 0.0 0.071 12.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EPS25178.1 - 0.0077 15.8 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 EPS25178.1 - 0.008 15.8 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase CDC45 PF02724.9 EPS25178.1 - 0.011 13.7 0.1 0.018 13.1 0.1 1.3 1 0 0 1 1 1 0 CDC45-like protein AAA PF00004.24 EPS25178.1 - 0.014 15.6 1.7 0.54 10.4 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPS25178.1 - 0.015 15.3 1.3 0.14 12.3 0.9 2.6 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EPS25178.1 - 0.016 14.6 0.2 0.059 12.8 0.1 1.9 1 1 1 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.1 EPS25178.1 - 0.018 15.3 0.0 0.061 13.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EPS25178.1 - 0.018 13.9 0.1 0.043 12.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 EPS25178.1 - 0.035 13.2 0.0 0.062 12.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.1 EPS25178.1 - 0.038 13.9 0.3 0.11 12.4 0.2 2.0 1 1 0 1 1 1 0 AAA ATPase domain ArgK PF03308.11 EPS25178.1 - 0.049 12.3 0.1 1.3 7.6 0.0 2.5 2 0 0 2 2 2 0 ArgK protein AAA_29 PF13555.1 EPS25178.1 - 0.066 12.7 0.1 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 EPS25178.1 - 0.069 13.0 0.2 0.22 11.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EPS25178.1 - 0.084 11.7 0.3 0.19 10.5 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain ABC_tran PF00005.22 EPS25178.1 - 0.1 12.8 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.1 EPS25178.1 - 0.17 11.6 0.1 0.47 10.2 0.0 1.8 2 0 0 2 2 1 0 Part of AAA domain AAA_11 PF13086.1 EPS25178.1 - 0.17 11.4 1.1 13 5.2 0.1 2.8 2 1 1 3 3 3 0 AAA domain adh_short PF00106.20 EPS25179.1 - 2.6e-19 69.7 0.0 3.5e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPS25179.1 - 1.2e-09 38.2 0.0 3e-09 37.0 0.0 1.5 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPS25179.1 - 0.00072 19.2 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EPS25179.1 - 0.0048 16.9 0.2 0.01 15.8 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPS25179.1 - 0.061 12.7 0.7 0.15 11.4 0.5 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family His_Phos_2 PF00328.17 EPS25180.1 - 1.8e-19 70.2 0.0 1.1e-18 67.7 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Lactamase_B_2 PF12706.2 EPS25181.1 - 1.9e-30 105.9 0.0 3.3e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 EPS25181.1 - 2.1e-22 78.3 0.0 6.3e-22 76.8 0.0 1.9 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.22 EPS25181.1 - 7.4e-06 25.7 0.0 1.6e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily bZIP_1 PF00170.16 EPS25182.1 - 1.5e-07 31.2 12.0 3.1e-07 30.2 8.3 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EPS25182.1 - 0.00019 21.1 11.4 0.00019 21.1 7.9 2.1 2 0 0 2 2 2 1 Basic region leucine zipper Tub_2 PF04525.7 EPS25183.1 - 1.3e-08 34.5 0.0 1.6e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 Tubby C 2 Peptidase_S24 PF00717.18 EPS25185.1 - 2.5e-07 30.2 0.0 4.3e-07 29.4 0.0 1.4 1 1 0 1 1 1 1 Peptidase S24-like MBOAT_2 PF13813.1 EPS25186.1 - 1.5e-22 79.4 1.3 4.1e-22 78.0 0.9 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF1509 PF07420.6 EPS25187.1 - 5.5 6.1 6.4 5.8 6.0 4.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) ABC_membrane_2 PF06472.10 EPS25188.1 - 3.6e-110 367.5 0.4 3.6e-110 367.5 0.3 1.5 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EPS25188.1 - 8.4e-19 68.2 0.0 1.7e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EPS25188.1 - 0.00011 22.3 0.0 0.00037 20.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 EPS25188.1 - 0.012 15.9 0.0 0.028 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EPS25188.1 - 0.018 14.5 0.0 0.047 13.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SMC_N PF02463.14 EPS25188.1 - 0.024 13.8 0.0 0.11 11.6 0.0 2.0 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EPS25188.1 - 0.042 13.8 0.9 0.18 11.8 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain DUF258 PF03193.11 EPS25188.1 - 0.12 11.5 0.0 0.24 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 HAD PF12710.2 EPS25189.1 - 6.7e-11 42.7 0.0 1e-10 42.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EPS25189.1 - 0.0011 18.2 0.0 0.36 9.9 0.0 2.1 2 0 0 2 2 2 2 Putative Phosphatase HAD_2 PF13419.1 EPS25189.1 - 0.0035 17.5 0.3 4.8 7.3 0.0 3.1 2 2 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPS25189.1 - 0.0078 16.6 0.0 0.15 12.4 0.0 2.2 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Phosphorylase PF00343.15 EPS25190.1 - 0 1076.4 0.2 0 1076.1 0.1 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Coatomer_b_Cpla PF14806.1 EPS25190.1 - 0.022 14.4 0.0 0.058 13.0 0.0 1.7 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform G-alpha PF00503.15 EPS25193.1 - 2.6e-124 414.8 0.2 2.8e-124 414.7 0.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EPS25193.1 - 3e-15 55.9 1.5 1.9e-10 40.2 0.1 2.7 2 2 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EPS25193.1 - 0.00019 20.6 0.1 0.35 9.9 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 EPS25193.1 - 0.0012 19.3 0.0 0.64 10.5 0.0 2.7 3 0 0 3 3 3 2 Miro-like protein AAA_29 PF13555.1 EPS25193.1 - 0.044 13.3 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EPS25193.1 - 0.15 12.0 0.1 2.9 7.8 0.1 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase Pkinase PF00069.20 EPS25194.1 - 9.2e-74 247.8 0.0 1.1e-73 247.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS25194.1 - 3.7e-31 108.1 0.0 4.6e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EPS25194.1 - 3.5e-05 22.9 0.0 0.00012 21.2 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EPS25194.1 - 0.0002 20.4 0.0 0.047 12.6 0.0 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.18 EPS25194.1 - 0.00055 19.7 0.0 0.0017 18.1 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EPS25194.1 - 0.052 12.9 0.0 0.078 12.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Avl9 PF09794.4 EPS25195.1 - 8.1e-138 459.0 0.0 1.1e-137 458.5 0.0 1.2 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 EPS25195.1 - 1.1e-07 31.5 0.0 0.0012 18.4 0.0 2.6 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.4 EPS25195.1 - 0.029 13.6 3.9 0.14 11.4 0.5 3.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) Cullin PF00888.17 EPS25196.1 - 3e-208 693.1 14.4 4.4e-208 692.5 10.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EPS25196.1 - 8.9e-28 95.9 3.6 8.9e-28 95.9 2.5 3.1 3 0 0 3 3 3 1 Cullin protein neddylation domain CTD_bind PF04818.8 EPS25196.1 - 0.054 13.7 4.5 31 4.9 0.0 4.9 5 1 0 5 5 5 0 RNA polymerase II-binding domain. WGG PF10273.4 EPS25196.1 - 0.33 11.0 7.3 17 5.5 0.0 4.7 4 0 0 4 4 4 0 Pre-rRNA-processing protein TSR2 Kinase-PPPase PF03618.9 EPS25196.1 - 0.73 9.2 7.1 6.5 6.1 0.4 2.4 2 0 0 2 2 2 0 Kinase/pyrophosphorylase Cupin_2 PF07883.6 EPS25197.1 - 2.7e-07 29.9 0.4 1.5e-06 27.6 0.2 2.0 1 1 1 2 2 2 1 Cupin domain Cupin_1 PF00190.17 EPS25197.1 - 2.9e-06 26.7 0.2 4.5e-06 26.1 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.2 EPS25197.1 - 0.0005 19.7 0.1 0.00062 19.4 0.1 1.2 1 0 0 1 1 1 1 Cupin ARD PF03079.9 EPS25197.1 - 0.0011 18.9 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 ARD/ARD' family AraC_binding PF02311.14 EPS25197.1 - 0.096 12.3 0.3 0.14 11.8 0.2 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain FhuF PF06276.7 EPS25198.1 - 0.12 12.2 2.2 0.58 10.0 0.1 2.5 2 1 0 2 2 2 0 Ferric iron reductase FhuF-like transporter MARVEL PF01284.18 EPS25198.1 - 0.17 11.6 3.3 0.31 10.8 2.3 1.4 1 1 0 1 1 1 0 Membrane-associating domain Mit_KHE1 PF10173.4 EPS25199.1 - 8.6e-66 221.3 1.3 8.6e-66 221.3 0.9 1.5 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related End3 PF12761.2 EPS25200.1 - 4.9e-75 251.4 1.2 6.8e-75 251.0 0.8 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 EPS25200.1 - 3.7e-50 168.0 0.1 1.4e-47 159.7 0.1 2.3 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 EPS25200.1 - 1.2e-07 30.5 0.3 3.3e-07 29.1 0.2 1.8 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 EPS25200.1 - 2.7e-07 30.1 0.1 9.1e-05 21.9 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.1 EPS25200.1 - 7.1e-06 26.0 0.0 2.5e-05 24.3 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EPS25200.1 - 4.7e-05 22.9 0.4 0.00039 20.0 0.1 2.5 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 EPS25200.1 - 0.00056 19.1 0.2 0.0019 17.4 0.1 1.9 1 0 0 1 1 1 1 EF hand TPR_MLP1_2 PF07926.7 EPS25200.1 - 0.017 14.8 1.4 0.017 14.8 0.9 2.4 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Rabaptin PF03528.10 EPS25200.1 - 0.021 14.7 7.0 0.056 13.3 4.8 1.7 1 0 0 1 1 1 0 Rabaptin MAGSP PF03082.9 EPS25200.1 - 0.13 11.6 0.1 0.21 10.9 0.1 1.3 1 0 0 1 1 1 0 Male accessory gland secretory protein DUF1409 PF07197.7 EPS25200.1 - 0.15 12.1 2.1 0.25 11.4 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1409) Spc7 PF08317.6 EPS25200.1 - 2.3 6.7 8.8 0.33 9.5 2.4 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF4201 PF13870.1 EPS25200.1 - 2.9 7.2 12.3 0.39 10.1 4.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) SNF2_N PF00176.18 EPS25201.1 - 4.8e-69 232.4 0.7 9.3e-69 231.4 0.0 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPS25201.1 - 2.2e-16 59.4 0.0 7.1e-16 57.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RseA_N PF03872.8 EPS25202.1 - 0.1 12.8 0.4 1.1 9.5 0.0 2.6 3 0 0 3 3 3 0 Anti sigma-E protein RseA, N-terminal domain DSPc PF00782.15 EPS25203.1 - 6.3e-14 51.6 0.0 9.5e-14 51.1 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 EPS25203.1 - 0.0041 16.0 0.0 0.0048 15.8 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Y_phosphatase PF00102.22 EPS25203.1 - 0.084 12.1 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DUF442 PF04273.8 EPS25203.1 - 0.1 12.4 0.0 0.96 9.3 0.0 2.2 1 1 0 1 1 1 0 Putative phosphatase (DUF442) Phage_Nu1 PF07471.7 EPS25203.1 - 0.15 11.5 1.0 7.7 5.9 0.0 2.1 1 1 0 2 2 2 0 Phage DNA packaging protein Nu1 zf-C2H2_4 PF13894.1 EPS25204.1 - 1.7e-07 31.0 9.9 0.045 14.0 0.3 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EPS25204.1 - 5.6e-05 23.2 14.1 0.38 11.2 1.8 3.8 3 1 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EPS25204.1 - 0.0053 16.9 12.9 0.0079 16.4 0.1 3.5 3 0 0 3 3 3 1 Zinc-finger double domain CCDC92 PF14916.1 EPS25204.1 - 0.013 15.0 0.5 0.03 13.9 0.3 1.6 1 1 0 1 1 1 0 Coiled-coil domain of unknown function IncA PF04156.9 EPS25204.1 - 0.045 13.3 0.1 0.071 12.6 0.1 1.3 1 0 0 1 1 1 0 IncA protein DUF3505 PF12013.3 EPS25204.1 - 0.084 13.1 0.0 0.084 13.1 0.0 2.8 2 2 2 4 4 4 0 Protein of unknown function (DUF3505) TMF_DNA_bd PF12329.3 EPS25204.1 - 0.097 12.4 0.2 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding H-kinase_dim PF02895.9 EPS25204.1 - 0.1 12.9 0.4 0.18 12.1 0.0 1.7 2 0 0 2 2 1 0 Signal transducing histidine kinase, homodimeric domain zf-H2C2_5 PF13909.1 EPS25204.1 - 0.2 11.9 1.0 3.7 7.9 0.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain MCPVI PF02993.9 EPS25204.1 - 0.21 11.7 2.3 0.45 10.6 1.6 1.5 1 0 0 1 1 1 0 Minor capsid protein VI Transpos_assoc PF13963.1 EPS25204.1 - 0.94 9.5 4.6 0.31 11.0 0.4 2.0 2 0 0 2 2 2 0 Transposase-associated domain UPF1_Zn_bind PF09416.5 EPS25205.1 - 1.7e-73 245.2 2.1 1.7e-73 245.2 1.4 1.8 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 EPS25205.1 - 3e-59 199.7 0.0 6e-59 198.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EPS25205.1 - 1.1e-56 192.0 1.1 1.7e-56 191.4 0.8 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPS25205.1 - 1.2e-14 53.7 0.2 3.8e-14 52.1 0.2 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EPS25205.1 - 6.9e-12 45.3 0.3 1.7e-10 40.8 0.2 2.5 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EPS25205.1 - 2e-07 31.0 0.0 3.8e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.13 EPS25205.1 - 1e-05 25.1 0.2 0.096 12.1 0.0 2.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 EPS25205.1 - 0.00051 19.7 0.0 0.001 18.7 0.0 1.5 1 0 0 1 1 1 1 Helicase DUF2075 PF09848.4 EPS25205.1 - 0.00083 18.4 1.0 0.0049 15.8 0.0 2.6 3 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) UvrD-helicase PF00580.16 EPS25205.1 - 0.0014 18.0 0.0 0.033 13.5 0.0 2.6 2 1 0 3 3 3 1 UvrD/REP helicase N-terminal domain PIF1 PF05970.9 EPS25205.1 - 0.0026 16.7 0.1 0.47 9.3 0.0 2.2 2 0 0 2 2 2 1 PIF1-like helicase DEAD PF00270.24 EPS25205.1 - 0.013 14.9 0.0 0.03 13.8 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase Ribosomal_S13_N PF08069.7 EPS25205.1 - 0.016 15.0 0.0 0.043 13.6 0.0 1.7 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain AAA_16 PF13191.1 EPS25205.1 - 0.022 14.7 0.1 0.043 13.7 0.1 1.4 1 0 0 1 1 1 0 AAA ATPase domain KaiC PF06745.8 EPS25205.1 - 0.041 12.9 0.0 0.087 11.9 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.1 EPS25205.1 - 0.052 12.9 0.0 0.098 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EPS25205.1 - 0.1 12.7 0.1 0.31 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 EPS25205.1 - 0.18 10.6 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.24 EPS25205.1 - 0.22 11.7 0.5 0.6 10.3 0.4 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Brix PF04427.13 EPS25206.1 - 1.4e-47 161.8 0.1 1.7e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 Brix domain PTCB-BRCT PF12738.2 EPS25207.1 - 4.5e-07 29.6 0.1 1e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EPS25207.1 - 7.4e-05 22.8 0.0 0.00014 21.9 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain WGR PF05406.10 EPS25207.1 - 0.0081 16.0 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 WGR domain IGPS PF00218.16 EPS25208.1 - 3.4e-97 324.4 0.1 1.4e-96 322.4 0.0 1.9 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 EPS25208.1 - 9.1e-60 201.5 0.1 2e-57 193.9 0.0 2.7 2 1 1 3 3 3 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 EPS25208.1 - 2e-50 170.9 0.0 4.7e-50 169.7 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EPS25208.1 - 0.00011 21.7 0.4 0.00038 19.9 0.2 1.8 1 1 0 1 1 1 1 Peptidase C26 IMPDH PF00478.20 EPS25208.1 - 0.00018 20.5 0.0 0.36 9.6 0.0 2.8 2 1 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain QRPTase_C PF01729.14 EPS25208.1 - 0.00026 20.5 0.6 0.033 13.7 0.0 3.6 3 0 0 3 3 3 1 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.16 EPS25208.1 - 0.0084 15.3 0.8 0.066 12.4 0.0 2.4 3 0 0 3 3 3 1 Histidine biosynthesis protein NanE PF04131.9 EPS25208.1 - 0.1 11.5 2.9 0.5 9.3 0.0 2.9 4 0 0 4 4 4 0 Putative N-acetylmannosamine-6-phosphate epimerase Nup188 PF10487.4 EPS25209.1 - 8.7e-54 182.8 4.2 4.2e-53 180.5 2.8 1.9 1 1 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 AMP-binding PF00501.23 EPS25210.1 - 6.7e-85 284.9 0.0 8.5e-85 284.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPS25210.1 - 4.2e-11 43.6 0.0 9.7e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Use1 PF09753.4 EPS25213.1 - 7.9e-07 28.7 10.0 1.6e-06 27.7 6.9 1.5 1 1 0 1 1 1 1 Membrane fusion protein Use1 DUF572 PF04502.8 EPS25213.1 - 1.5 7.9 19.0 1.7 7.7 12.9 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF572) Synaptobrevin PF00957.16 EPS25213.1 - 1.9 8.1 5.1 2.2 7.9 1.6 2.5 2 1 1 3 3 3 0 Synaptobrevin G-alpha PF00503.15 EPS25214.1 - 4e-134 447.1 1.9 4.9e-134 446.8 1.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EPS25214.1 - 2.1e-15 56.3 1.7 2e-10 40.1 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 EPS25214.1 - 8.5e-05 22.0 0.0 0.00037 19.9 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Miro PF08477.8 EPS25214.1 - 0.0014 19.1 0.7 2.6 8.5 0.1 2.8 2 2 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 EPS25214.1 - 0.0071 15.5 3.1 0.21 10.6 0.1 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 EPS25214.1 - 0.011 15.2 0.0 0.027 14.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EPS25214.1 - 0.018 14.4 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_23 PF13476.1 EPS25214.1 - 0.038 14.2 0.1 0.095 13.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EPS25214.1 - 0.094 12.6 0.0 15 5.6 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EPS25214.1 - 0.14 11.6 0.0 0.31 10.4 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family HNH_2 PF13391.1 EPS25215.1 - 0.007 16.1 0.0 0.0086 15.8 0.0 1.3 1 1 0 1 1 1 1 HNH endonuclease HNH PF01844.18 EPS25215.1 - 0.034 14.0 1.1 0.81 9.6 0.1 2.3 2 0 0 2 2 2 0 HNH endonuclease DUF1771 PF08590.5 EPS25216.1 - 6.6e-25 86.9 7.5 1.9e-24 85.4 5.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 EPS25216.1 - 8e-16 58.0 0.3 8e-16 58.0 0.2 2.2 3 0 0 3 3 3 1 Smr domain Zip PF02535.17 EPS25216.1 - 4.6 6.1 5.2 5 6.0 3.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter polyprenyl_synt PF00348.12 EPS25217.1 - 1.6e-60 204.2 0.0 1.9e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.11 EPS25217.1 - 0.056 12.6 0.0 0.088 12.0 0.0 1.3 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain CDC14 PF08045.6 EPS25218.1 - 2.3e-99 331.6 0.0 2.7e-99 331.5 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component Methyltransf_31 PF13847.1 EPS25219.1 - 1.1e-11 44.5 0.0 2.7e-11 43.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS25219.1 - 8.4e-10 39.2 0.0 4.6e-09 36.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPS25219.1 - 1.1e-08 34.9 0.0 1.7e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPS25219.1 - 2.5e-08 34.3 0.0 6.4e-07 29.7 0.0 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPS25219.1 - 5.7e-08 33.0 0.0 1.2e-07 31.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPS25219.1 - 1.5e-06 28.6 0.0 4e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPS25219.1 - 6.3e-05 22.2 0.0 9.4e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EPS25219.1 - 0.0016 18.4 0.0 0.0044 17.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EPS25219.1 - 0.0083 15.2 0.0 0.28 10.2 0.0 2.3 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 EPS25219.1 - 0.013 15.0 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_7 PF03492.10 EPS25219.1 - 0.045 12.5 0.0 0.096 11.4 0.0 1.5 2 0 0 2 2 2 0 SAM dependent carboxyl methyltransferase TehB PF03848.9 EPS25219.1 - 0.055 12.6 0.0 0.22 10.6 0.0 2.0 2 0 0 2 2 2 0 Tellurite resistance protein TehB MTS PF05175.9 EPS25219.1 - 0.09 12.1 0.2 2 7.7 0.1 2.7 1 1 0 1 1 1 0 Methyltransferase small domain Tom37 PF10568.4 EPS25220.1 - 3e-05 24.1 0.0 6.4e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein DUF2731 PF10806.3 EPS25220.1 - 0.00011 22.4 0.3 0.00025 21.2 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2731) GST_C_3 PF14497.1 EPS25220.1 - 0.0029 18.0 0.1 0.0065 16.9 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EPS25220.1 - 0.0037 17.1 0.4 0.0085 15.9 0.2 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37_C PF11801.3 EPS25220.1 - 0.058 13.2 0.1 3.2 7.5 0.2 2.2 1 1 1 2 2 2 0 Tom37 C-terminal domain Copper-fist PF00649.13 EPS25221.1 - 1.2e-19 69.1 0.3 4.2e-19 67.4 0.2 2.0 1 0 0 1 1 1 1 Copper fist DNA binding domain Urb2 PF10441.4 EPS25222.1 - 2.7e-62 210.2 2.1 6.8e-62 208.9 0.0 2.6 2 0 0 2 2 2 1 Urb2/Npa2 family DUF543 PF04418.7 EPS25223.1 - 1.5e-27 95.3 0.1 1.7e-27 95.1 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Transp_cyt_pur PF02133.10 EPS25224.1 - 9e-153 508.9 38.3 1.1e-152 508.7 26.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PI-PLC-X PF00388.14 EPS25225.1 - 2.4e-58 195.6 0.0 4.7e-58 194.7 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EPS25225.1 - 1.5e-40 137.8 0.4 2.3e-39 134.0 0.2 2.4 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 EPS25225.1 - 1.6e-07 31.2 0.1 8.3e-07 28.9 0.0 2.2 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_7 PF13499.1 EPS25225.1 - 3.5e-05 23.8 0.2 0.42 10.7 0.0 2.8 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EPS25225.1 - 0.00019 20.5 0.0 0.00099 18.2 0.0 2.2 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 EPS25225.1 - 0.0021 17.7 0.3 0.28 11.1 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.1 EPS25225.1 - 0.0025 17.3 0.0 0.022 14.3 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain pair GDPD PF03009.12 EPS25225.1 - 0.0049 16.3 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family RVT_1 PF00078.22 EPS25227.1 - 1.4e-05 24.5 0.0 2.9e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) U5_2-snRNA_bdg PF10597.4 EPS25227.1 - 0.11 12.1 0.1 0.29 10.7 0.0 1.7 1 0 0 1 1 1 0 U5-snRNA binding site 2 of PrP8 Coatomer_E PF04733.9 EPS25229.1 - 1.3e-58 198.5 7.0 1.4e-58 198.3 4.8 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 EPS25229.1 - 2e-08 34.4 26.8 0.0035 17.6 2.8 4.4 3 2 1 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EPS25229.1 - 1.7e-07 31.6 19.3 0.0026 18.3 0.5 4.4 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EPS25229.1 - 1.3e-06 28.4 21.2 0.00061 20.1 0.3 5.5 3 2 3 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EPS25229.1 - 5.8e-05 23.2 6.5 0.022 15.1 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EPS25229.1 - 8.6e-05 22.5 6.2 0.27 11.3 0.5 3.6 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 EPS25229.1 - 0.005 17.1 24.6 0.26 11.8 0.1 5.9 6 1 1 7 7 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 EPS25229.1 - 0.0056 16.2 10.6 0.028 14.0 0.0 3.8 3 2 0 4 4 4 1 TPR repeat TPR_2 PF07719.12 EPS25229.1 - 0.021 14.7 0.1 0.021 14.7 0.1 5.1 6 0 0 6 6 4 0 Tetratricopeptide repeat DUF3366 PF11846.3 EPS25229.1 - 0.063 13.1 4.5 0.2 11.5 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3366) Alkyl_sulf_dimr PF14863.1 EPS25229.1 - 0.15 12.3 2.5 0.2 11.8 0.6 2.0 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation TPR_1 PF00515.23 EPS25229.1 - 0.3 10.7 0.0 0.3 10.7 0.0 3.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 EPS25229.1 - 0.62 10.0 15.5 2 8.3 0.4 4.1 2 1 3 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.1 EPS25229.1 - 1.3 9.3 4.2 46 4.5 0.2 4.2 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.1 EPS25229.1 - 1.5 8.9 11.3 0.98 9.5 2.6 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 EPS25229.1 - 3.3 7.6 11.7 0.71 9.7 0.1 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat Abhydrolase_3 PF07859.8 EPS25230.1 - 7.3e-28 97.5 0.0 1e-27 97.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EPS25230.1 - 1.4e-20 73.3 0.0 2e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EPS25230.1 - 4.6e-09 36.1 0.1 7.1e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EPS25230.1 - 0.00057 19.3 0.1 0.036 13.5 0.0 2.9 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase DUF2974 PF11187.3 EPS25230.1 - 0.0031 16.8 0.0 0.006 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) PGAP1 PF07819.8 EPS25230.1 - 0.026 14.1 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_S9 PF00326.16 EPS25230.1 - 0.049 12.8 0.1 0.092 11.9 0.1 1.7 1 1 0 1 1 1 0 Prolyl oligopeptidase family PMI_typeI PF01238.16 EPS25231.1 - 1.3e-145 485.1 0.0 1.5e-145 484.8 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.14 EPS25231.1 - 0.027 14.1 0.5 6.3 6.4 0.0 3.1 4 0 0 4 4 4 0 AraC-like ligand binding domain Cupin_2 PF07883.6 EPS25231.1 - 0.075 12.5 0.2 1.4 8.5 0.1 2.2 2 0 0 2 2 2 0 Cupin domain YkuI_C PF10388.4 EPS25231.1 - 0.23 11.1 0.4 0.55 9.9 0.0 1.8 2 0 0 2 2 2 0 EAL-domain associated signalling protein domain DUF1325 PF07039.6 EPS25232.1 - 6.1e-29 100.2 0.0 9.7e-29 99.6 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain TATR PF03430.8 EPS25232.1 - 0.16 10.6 4.9 0.21 10.2 3.4 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator V_ATPase_I PF01496.14 EPS25232.1 - 0.7 7.6 3.4 0.9 7.3 2.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GTP_cyclohydro2 PF00925.15 EPS25233.1 - 1.2e-55 187.3 0.0 1.7e-50 170.5 0.0 2.1 2 0 0 2 2 2 2 GTP cyclohydrolase II DUF3425 PF11905.3 EPS25234.1 - 2.1e-35 121.5 3.8 4e-35 120.6 2.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EPS25234.1 - 0.031 14.2 7.5 0.11 12.4 4.7 2.1 1 1 1 2 2 2 0 bZIP transcription factor DUF2730 PF10805.3 EPS25234.1 - 0.21 11.3 1.4 0.45 10.2 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF3584 PF12128.3 EPS25234.1 - 0.69 7.1 7.2 0.95 6.7 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Dicty_REP PF05086.7 EPS25234.1 - 4.6 4.8 3.6 6 4.4 2.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein bZIP_2 PF07716.10 EPS25234.1 - 6 6.7 9.9 34 4.3 6.9 2.0 1 1 1 2 2 2 0 Basic region leucine zipper NAD_binding_2 PF03446.10 EPS25235.1 - 3.9e-20 72.3 0.0 5.6e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EPS25235.1 - 3.5e-11 43.2 0.0 6.5e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Actin PF00022.14 EPS25236.1 - 1.1e-116 389.4 0.0 1.5e-116 389.0 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EPS25236.1 - 0.021 13.4 0.0 0.068 11.7 0.0 1.9 1 1 0 1 1 1 0 MreB/Mbl protein adh_short PF00106.20 EPS25237.1 - 4.6e-29 101.4 0.0 6.7e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPS25237.1 - 2.5e-26 92.9 0.0 3.2e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPS25237.1 - 4e-13 49.4 0.0 5.6e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EPS25237.1 - 0.0054 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2-Hacid_dh_C PF02826.14 EPS25237.1 - 0.023 13.8 0.0 1.5 7.9 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 EPS25237.1 - 0.051 12.6 0.0 0.095 11.7 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Epimerase PF01370.16 EPS25237.1 - 0.052 12.9 0.0 0.071 12.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EPS25237.1 - 0.15 11.1 0.0 0.22 10.5 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) adh_short PF00106.20 EPS25238.1 - 1.1e-25 90.4 1.7 4.6e-24 85.2 0.1 2.4 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPS25238.1 - 4.3e-23 82.3 2.4 8.4e-23 81.3 1.6 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPS25238.1 - 1.2e-11 44.6 0.1 3.3e-11 43.1 0.0 1.6 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 EPS25238.1 - 6.7e-05 23.0 0.4 0.00018 21.6 0.3 1.8 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EPS25238.1 - 0.00034 20.6 0.8 0.0013 18.7 0.2 2.1 2 1 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EPS25238.1 - 0.0026 17.2 0.5 0.0051 16.2 0.1 1.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EPS25238.1 - 0.0029 16.7 1.0 0.0065 15.6 0.1 1.8 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) Glyco_tran_WecB PF03808.8 EPS25238.1 - 0.0088 15.4 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase WecB/TagA/CpsF family ADH_zinc_N PF00107.21 EPS25238.1 - 0.03 13.8 0.0 0.079 12.5 0.0 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.3 EPS25238.1 - 0.087 12.6 0.2 0.23 11.2 0.2 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_7 PF13241.1 EPS25238.1 - 0.15 12.2 0.7 0.77 10.0 0.1 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding DUF202 PF02656.10 EPS25239.1 - 5.7e-26 90.5 1.5 5.7e-26 90.5 1.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF202) PTPA PF03095.10 EPS25240.1 - 1e-109 366.3 0.0 1.2e-109 366.1 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein MFS_1 PF07690.11 EPS25241.1 - 5.3e-15 54.9 10.5 5.3e-15 54.9 7.3 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS25241.1 - 1.9e-08 33.3 2.6 1.9e-08 33.3 1.8 2.7 2 2 0 2 2 2 1 Sugar (and other) transporter HSP20 PF00011.16 EPS25242.1 - 7.3e-19 67.5 0.1 1.8e-12 46.9 0.0 2.2 1 1 1 2 2 2 2 Hsp20/alpha crystallin family DUF1754 PF08555.5 EPS25243.1 - 8.6e-18 64.7 12.8 8.6e-18 64.7 8.9 1.8 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) Sec2p PF06428.6 EPS25243.1 - 0.027 14.2 1.2 0.027 14.2 0.8 1.9 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Phage_term_sma PF07141.6 EPS25243.1 - 0.27 10.7 3.2 0.19 11.2 0.2 1.8 2 0 0 2 2 2 0 Putative bacteriophage terminase small subunit PIH1 PF08190.7 EPS25243.1 - 1.2 8.5 8.8 1.4 8.2 6.1 1.1 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Trypan_PARP PF05887.6 EPS25243.1 - 2.1 8.1 10.0 2.7 7.7 7.0 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) zf-AN1 PF01428.11 EPS25244.1 - 3.4e-11 42.8 14.6 4.8e-11 42.3 10.1 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger DJ-1_PfpI PF01965.19 EPS25244.1 - 0.086 12.2 0.2 0.09 12.2 0.2 1.1 1 0 0 1 1 1 0 DJ-1/PfpI family Tubulin PF00091.20 EPS25247.1 - 4.6e-72 242.3 0.0 6.9e-72 241.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EPS25247.1 - 6.1e-46 155.5 0.5 9e-46 155.0 0.1 1.5 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EPS25247.1 - 4.4e-07 29.9 0.0 1e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Asp_Glu_race PF01177.17 EPS25248.1 - 9.2e-15 55.1 0.0 1.1e-14 54.9 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Aldo_ket_red PF00248.16 EPS25249.1 - 1.1e-55 188.4 0.0 1.3e-55 188.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family EamA PF00892.15 EPS25250.1 - 3.4e-12 46.5 25.5 7.1e-06 26.0 0.7 2.6 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EPS25250.1 - 1.6e-06 28.2 18.9 8e-05 22.8 0.1 2.7 2 0 0 2 2 2 2 Multidrug resistance efflux transporter TPT PF03151.11 EPS25250.1 - 0.00074 19.1 15.2 0.003 17.1 6.3 2.7 2 1 0 2 2 2 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 EPS25250.1 - 0.0039 16.3 0.1 0.0039 16.3 0.1 2.1 2 0 0 2 2 2 1 Nucleotide-sugar transporter DAP10 PF07213.6 EPS25250.1 - 2.2 8.1 4.7 49 3.7 0.4 3.5 4 0 0 4 4 4 0 DAP10 membrane protein Fcf1 PF04900.7 EPS25255.1 - 0.046 13.8 0.0 0.05 13.6 0.0 1.1 1 0 0 1 1 1 0 Fcf1 DUF3115 PF11312.3 EPS25256.1 - 1.9e-103 345.6 0.0 2.8e-103 345.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) Rsm22 PF09243.5 EPS25256.1 - 0.068 12.1 0.1 0.18 10.8 0.1 1.7 1 1 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 DUF938 PF06080.7 EPS25256.1 - 0.11 11.9 0.2 3 7.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Band_7 PF01145.20 EPS25257.1 - 1.3e-25 90.2 7.6 1.4e-25 90.2 4.2 1.7 1 1 1 2 2 2 1 SPFH domain / Band 7 family UcrQ PF02939.11 EPS25258.1 - 2.1e-26 91.5 0.1 2.7e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 UcrQ family Spermine_synth PF01564.12 EPS25259.1 - 2.5e-95 318.0 0.0 3.1e-95 317.8 0.0 1.0 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_12 PF08242.7 EPS25259.1 - 0.019 15.4 0.4 0.29 11.6 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.1 EPS25259.1 - 0.061 13.6 0.0 0.15 12.4 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.1 EPS25259.1 - 0.067 12.9 0.0 0.2 11.3 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EPS25259.1 - 0.079 13.5 0.0 0.15 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain 3HCDH_N PF02737.13 EPS25260.1 - 1.5e-25 89.8 0.0 2.8e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EPS25260.1 - 9.3e-10 38.7 0.0 1.9e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Transketolase_N PF00456.16 EPS25261.1 - 1e-147 491.3 0.0 1.4e-147 490.9 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EPS25261.1 - 3e-44 150.6 0.0 5.4e-44 149.8 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EPS25261.1 - 8.5e-13 48.3 0.0 1.9e-12 47.2 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 EPS25261.1 - 1.6e-05 24.0 0.0 4.6e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 EPS25261.1 - 0.0028 16.4 0.0 0.0048 15.6 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component GFA PF04828.9 EPS25263.1 - 3e-23 81.5 0.3 3.6e-23 81.3 0.2 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 EPS25263.1 - 0.0091 15.1 3.7 0.036 13.2 0.1 2.4 2 0 0 2 2 2 1 zinc-ribbon domain DZR PF12773.2 EPS25263.1 - 0.061 13.1 2.0 0.31 10.8 0.0 2.2 2 0 0 2 2 2 0 Double zinc ribbon Nudix_N_2 PF14803.1 EPS25263.1 - 0.068 12.8 0.4 0.068 12.8 0.3 2.6 2 1 1 3 3 3 0 Nudix N-terminal Auto_anti-p27 PF06677.7 EPS25263.1 - 0.078 12.7 3.1 0.085 12.6 0.0 2.3 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Sugar_tr PF00083.19 EPS25264.1 - 2.8e-137 458.0 27.8 3.2e-137 457.8 19.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS25264.1 - 2.1e-26 92.4 50.8 9.3e-20 70.6 16.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_A14 PF05767.7 EPS25264.1 - 0.39 10.7 0.0 0.39 10.7 0.0 3.4 4 0 0 4 4 4 0 Poxvirus virion envelope protein A14 DUF3959 PF13105.1 EPS25264.1 - 0.87 8.8 4.5 2.4 7.4 3.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Fungal_trans PF04082.13 EPS25265.1 - 9.7e-36 122.9 0.5 9.7e-36 122.9 0.4 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS25265.1 - 6.5e-08 32.3 14.7 1.1e-07 31.6 10.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cep57_MT_bd PF06657.8 EPS25265.1 - 0.27 11.2 2.9 5.4 7.0 0.2 2.6 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 SET PF00856.23 EPS25266.1 - 0.024 14.9 0.0 0.064 13.5 0.0 1.7 1 0 0 1 1 1 0 SET domain L27_2 PF09045.5 EPS25266.1 - 0.038 13.5 0.7 0.094 12.2 0.0 1.9 2 0 0 2 2 2 0 L27_2 RFXA_RFXANK_bdg PF15289.1 EPS25266.1 - 0.069 13.3 0.2 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Regulatory factor X-associated C-terminal binding domain MMR_HSR1_C PF08438.5 EPS25268.1 - 1.6e-31 108.7 0.0 3.1e-31 107.8 0.0 1.5 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 EPS25268.1 - 2.8e-18 65.9 0.0 6.2e-18 64.8 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EPS25268.1 - 9.1e-09 34.7 0.1 1.8e-07 30.5 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EPS25268.1 - 0.0003 20.2 0.0 0.13 11.7 0.0 2.6 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EPS25268.1 - 0.0028 17.4 1.1 0.16 11.7 0.2 2.9 3 0 0 3 3 3 1 Dynamin family ATP_bind_1 PF03029.12 EPS25268.1 - 0.013 15.0 0.1 3.6 7.0 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ArgK PF03308.11 EPS25268.1 - 0.045 12.5 0.1 0.22 10.2 0.0 2.0 2 0 0 2 2 2 0 ArgK protein AAA_18 PF13238.1 EPS25268.1 - 0.076 13.3 0.0 2 8.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 EPS25268.1 - 0.12 11.6 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_10 PF12846.2 EPS25268.1 - 0.12 11.7 0.0 0.55 9.6 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain DUF4330 PF14221.1 EPS25272.1 - 0.091 12.6 0.6 0.29 10.9 0.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4330) LST1 PF05083.8 EPS25272.1 - 0.15 12.1 0.7 0.41 10.6 0.5 1.8 1 0 0 1 1 1 0 LST-1 protein HCMVantigenic_N PF12154.3 EPS25272.1 - 4.9 7.1 5.9 0.53 10.2 0.4 2.0 2 0 0 2 2 2 0 Glycoprotein B N-terminal antigenic domain of HCMV Ribosomal_L7Ae PF01248.21 EPS25273.1 - 3.7e-20 71.2 1.6 2.8e-19 68.4 1.1 2.3 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family BON PF04972.12 EPS25273.1 - 0.071 12.8 7.7 0.3 10.8 0.1 2.6 2 0 0 2 2 2 0 BON domain D5_N PF08706.6 EPS25273.1 - 2.8 8.0 6.2 42 4.1 4.3 2.1 1 1 0 1 1 1 0 D5 N terminal like MAD PF05557.8 EPS25274.1 - 2.5e-55 187.8 75.1 2.8e-46 158.0 52.7 2.0 2 0 0 2 2 2 2 Mitotic checkpoint protein muHD PF10291.4 EPS25275.1 - 1.3e-76 257.2 0.0 2.4e-76 256.3 0.0 1.5 2 0 0 2 2 2 1 Muniscin C-terminal mu homology domain FCH PF00611.18 EPS25275.1 - 2.1e-11 43.8 0.2 3.8e-10 39.8 0.0 2.7 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain DUF1202 PF06717.6 EPS25275.1 - 0.035 13.3 0.2 0.068 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) Pkinase PF00069.20 EPS25276.1 - 1.6e-39 135.6 0.0 2.2e-39 135.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS25276.1 - 1.6e-12 47.0 0.0 2.4e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPS25276.1 - 7.9e-07 29.0 2.1 0.0017 18.1 0.3 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EPS25276.1 - 0.0011 17.9 0.0 0.0016 17.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EPS25276.1 - 0.015 14.6 0.0 0.034 13.4 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 EPS25276.1 - 0.037 13.0 0.1 0.12 11.4 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Podoplanin PF05808.6 EPS25276.1 - 0.055 13.0 0.2 0.09 12.3 0.1 1.3 1 0 0 1 1 1 0 Podoplanin DUF3813 PF12758.2 EPS25276.1 - 5.4 7.2 6.6 4 7.6 1.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3813) SH3_9 PF14604.1 EPS25277.1 - 2.4e-09 36.6 0.0 3.8e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EPS25277.1 - 5e-06 25.8 0.0 7.7e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EPS25277.1 - 0.0014 18.0 0.0 0.003 17.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF2668 PF10873.3 EPS25277.1 - 0.0017 18.5 0.4 0.011 15.9 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2668) SKG6 PF08693.5 EPS25277.1 - 0.019 14.2 1.5 0.019 14.2 1.1 2.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain OPT PF03169.10 EPS25278.1 - 3.8e-176 587.1 12.1 4.4e-176 586.9 8.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Acetyltransf_1 PF00583.19 EPS25279.1 - 0.0093 15.9 0.1 0.014 15.4 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.1 EPS25279.1 - 0.095 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acyltransferase PF01553.16 EPS25281.1 - 3.5e-10 39.4 0.0 3.8e-09 36.0 0.0 2.3 1 1 0 1 1 1 1 Acyltransferase Rav1p_C PF12234.3 EPS25284.1 - 1.7e-278 925.0 0.0 2.2e-278 924.7 0.0 1.1 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.27 EPS25284.1 - 2.2e-06 27.3 0.2 0.84 9.6 0.0 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF3943 PF13084.1 EPS25284.1 - 0.037 13.5 0.1 0.11 12.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3943) Sfi1 PF08457.5 EPS25285.1 - 1.7e-179 597.9 85.8 1.7e-179 597.9 59.5 2.1 1 1 0 2 2 2 2 Sfi1 spindle body protein Cmc1 PF08583.5 EPS25286.1 - 0.014 15.1 1.4 0.014 15.1 0.9 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.8 EPS25286.1 - 0.015 14.6 1.5 2 7.8 0.0 2.1 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CHCH PF06747.8 EPS25286.1 - 0.14 12.0 2.5 0.98 9.4 1.7 2.0 1 1 1 2 2 2 0 CHCH domain UCR_hinge PF02320.11 EPS25286.1 - 0.17 11.8 1.5 0.24 11.3 1.1 1.3 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein tRNA-synt_1 PF00133.17 EPS25287.1 - 4.1e-225 748.3 0.0 5.7e-225 747.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EPS25287.1 - 1.1e-25 90.1 0.0 4e-25 88.3 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EPS25287.1 - 2e-18 66.2 0.2 1.7e-07 30.2 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) RE_MjaI PF09568.5 EPS25287.1 - 0.051 13.0 0.1 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 MjaI restriction endonuclease Uso1_p115_head PF04869.9 EPS25288.1 - 1.7e-105 352.2 0.0 4.9e-105 350.7 0.0 1.9 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 EPS25288.1 - 1.4e-07 31.4 36.9 1.4e-07 31.4 25.6 4.8 1 1 3 4 4 4 1 Uso1 / p115 like vesicle tethering protein, C terminal region Reo_sigmaC PF04582.7 EPS25288.1 - 3.2 6.8 36.2 0.03 13.5 3.3 4.2 1 1 3 4 4 4 0 Reovirus sigma C capsid protein Tropomyosin PF00261.15 EPS25288.1 - 9.1 5.2 86.9 0.29 10.1 8.1 4.0 1 1 2 3 3 3 0 Tropomyosin XRN_N PF03159.13 EPS25289.1 - 2e-108 361.2 3.5 6.5e-108 359.5 0.0 2.2 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus zf-CCHC PF00098.18 EPS25289.1 - 0.0024 17.7 1.5 0.0042 16.9 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle EPSP_synthase PF00275.15 EPS25290.1 - 1.6e-127 425.4 0.0 2.5e-127 424.7 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 EPS25290.1 - 1.4e-96 322.4 0.0 2.7e-96 321.5 0.0 1.5 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 EPS25290.1 - 3.1e-64 216.7 0.0 5.3e-64 215.9 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 EPS25290.1 - 8.2e-41 139.5 0.0 7.1e-40 136.4 0.0 2.2 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 EPS25290.1 - 3.5e-24 84.6 0.0 1e-23 83.1 0.0 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EPS25290.1 - 1.7e-12 47.5 0.0 4.7e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 EPS25290.1 - 4.5e-08 32.7 0.0 9.5e-08 31.6 0.0 1.5 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.14 EPS25290.1 - 8.7e-05 21.3 0.1 0.00021 20.0 0.0 1.6 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 EPS25290.1 - 0.00011 22.9 0.0 0.0038 18.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain Pyr_redox_3 PF13738.1 EPS25290.1 - 0.041 13.9 0.0 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AAA_24 PF13479.1 EPS25290.1 - 0.041 13.4 0.0 0.078 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EPS25290.1 - 0.13 12.1 0.0 0.35 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain p450 PF00067.17 EPS25291.1 - 2.6e-59 200.9 0.0 3.5e-59 200.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Polyketide_cyc2 PF10604.4 EPS25294.1 - 0.067 13.3 0.0 0.081 13.1 0.0 1.1 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport zf-C2H2 PF00096.21 EPS25297.1 - 5.1e-10 39.0 12.8 0.00032 20.8 0.9 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPS25297.1 - 4.5e-07 29.7 15.7 0.0026 17.9 0.9 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-BED PF02892.10 EPS25297.1 - 0.16 11.7 1.7 0.38 10.5 1.2 1.6 1 0 0 1 1 1 0 BED zinc finger zf-Di19 PF05605.7 EPS25297.1 - 0.76 9.9 6.7 2 8.6 1.0 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding F-box PF00646.28 EPS25298.1 - 3e-05 23.5 0.3 7e-05 22.3 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EPS25298.1 - 7.5e-05 22.3 0.9 0.00014 21.4 0.6 1.5 1 0 0 1 1 1 1 F-box-like Histone PF00125.19 EPS25299.1 - 1.6e-15 56.9 0.1 1.9e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 EPS25299.1 - 0.0001 22.1 0.1 0.00015 21.6 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 EPS25299.1 - 0.00012 22.1 0.1 0.00018 21.6 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EPS25299.1 - 0.00017 21.5 0.1 0.0003 20.7 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EPS25299.1 - 0.018 14.7 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 EPS25299.1 - 0.022 14.0 0.0 0.022 13.9 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Histone PF00125.19 EPS25300.1 - 1.1e-31 108.7 0.4 1.8e-31 108.0 0.3 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EPS25300.1 - 2.9e-06 27.3 0.0 4.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EPS25300.1 - 0.0035 17.3 0.3 0.0073 16.3 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EPS25300.1 - 0.04 13.6 0.1 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated HRM PF02793.17 EPS25302.1 - 0.013 15.5 0.2 0.016 15.1 0.1 1.1 1 0 0 1 1 1 0 Hormone receptor domain MFS_1 PF07690.11 EPS25303.1 - 1.9e-39 135.3 49.8 2.4e-39 135.0 30.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS25303.1 - 5.1e-08 31.9 14.5 5.1e-08 31.9 10.1 2.8 2 1 1 3 3 3 1 Sugar (and other) transporter OATP PF03137.15 EPS25303.1 - 0.032 12.3 2.8 0.78 7.7 0.6 2.5 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Mpv17_PMP22 PF04117.7 EPS25304.1 - 2.2e-18 65.6 1.2 2.2e-18 65.6 0.9 2.0 2 1 1 3 3 3 1 Mpv17 / PMP22 family Exo5 PF09810.4 EPS25305.1 - 3.9e-123 410.8 0.0 4.8e-123 410.4 0.0 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 EPS25305.1 - 0.0002 20.8 3.5 0.0061 15.9 0.1 2.9 2 1 0 2 2 2 1 PD-(D/E)XK nuclease superfamily DUF3445 PF11927.3 EPS25306.1 - 5.2e-82 274.9 0.0 6.6e-82 274.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Glyco_transf_22 PF03901.12 EPS25307.1 - 6.5e-85 285.6 15.5 7.5e-85 285.4 10.8 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family zf-C3HC4_3 PF13920.1 EPS25307.1 - 0.17 11.5 0.4 0.31 10.7 0.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Gar1 PF04410.9 EPS25308.1 - 1.8e-44 150.9 0.2 1.8e-44 150.9 0.1 2.6 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region BicD PF09730.4 EPS25308.1 - 0.14 10.4 4.2 0.23 9.7 2.9 1.3 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D SDA1 PF05285.7 EPS25308.1 - 0.23 10.7 17.9 0.14 11.4 7.1 2.2 2 0 0 2 2 2 0 SDA1 PRP3 PF08572.5 EPS25309.1 - 3.8e-70 235.7 8.4 7.8e-70 234.7 5.8 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 EPS25309.1 - 8.6e-38 128.9 0.9 1.4e-37 128.2 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) RNA_pol_Rpb1_5 PF04998.12 EPS25310.1 - 6.5e-87 291.3 0.7 1.2e-86 290.3 0.1 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EPS25310.1 - 1.7e-63 213.5 0.0 3.9e-63 212.3 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EPS25310.1 - 5e-32 110.8 0.0 3.2e-31 108.2 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 EPS25310.1 - 2.2e-26 92.9 9.0 7e-23 81.4 0.0 3.6 4 0 0 4 4 4 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 EPS25310.1 - 3.6e-17 62.0 0.3 2.9e-16 59.1 0.0 2.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 Nop14 PF04147.7 EPS25310.1 - 0.14 10.0 18.1 0.25 9.2 12.6 1.3 1 0 0 1 1 1 0 Nop14-like family Fusion_gly PF00523.13 EPS25310.1 - 0.39 8.7 1.0 0.62 8.0 0.7 1.2 1 0 0 1 1 1 0 Fusion glycoprotein F0 DUF1227 PF06777.6 EPS25311.1 - 2.3e-63 212.2 0.6 5.1e-63 211.1 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 EPS25311.1 - 9.3e-49 165.1 0.6 1.7e-48 164.2 0.4 1.5 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 EPS25311.1 - 1.5e-44 151.9 0.0 3.3e-44 150.7 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD PF00270.24 EPS25311.1 - 0.001 18.5 0.0 0.11 12.0 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase PhoH PF02562.11 EPS25311.1 - 0.0024 17.1 0.3 1 8.5 0.0 3.2 3 0 0 3 3 3 1 PhoH-like protein SNF2_N PF00176.18 EPS25311.1 - 0.0039 16.0 0.1 0.053 12.3 0.0 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.1 EPS25311.1 - 0.013 15.6 0.2 1.9 8.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 EPS25311.1 - 0.017 14.9 0.2 0.16 11.7 0.1 2.3 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_11 PF13086.1 EPS25311.1 - 0.035 13.6 0.5 0.1 12.1 0.3 1.7 1 1 0 1 1 1 0 AAA domain Stomoxyn PF11585.3 EPS25311.1 - 0.2 11.4 0.1 0.4 10.5 0.1 1.5 1 0 0 1 1 1 0 Insect antimicrobial peptide, stomoxyn Remorin_C PF03763.8 EPS25311.1 - 7.8 6.0 8.6 0.43 10.1 1.6 2.1 2 0 0 2 2 2 0 Remorin, C-terminal region zf-rbx1 PF12678.2 EPS25312.1 - 2e-07 31.0 2.0 4.8e-07 29.8 1.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EPS25312.1 - 2.8e-07 30.2 8.2 2.8e-07 30.2 5.7 1.7 2 0 0 2 2 2 1 Ring finger domain FANCL_C PF11793.3 EPS25312.1 - 5.3e-05 23.0 6.2 0.00012 22.0 4.3 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-Apc11 PF12861.2 EPS25312.1 - 0.00014 21.6 2.2 0.00028 20.6 1.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 EPS25312.1 - 0.00047 19.7 11.7 0.00065 19.3 6.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 EPS25312.1 - 0.037 14.0 7.8 0.078 13.0 5.4 1.6 1 0 0 1 1 1 0 RING-variant domain C1_1 PF00130.17 EPS25312.1 - 0.054 13.2 5.9 0.12 12.0 4.1 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_2 PF13923.1 EPS25312.1 - 0.083 12.9 10.3 0.1 12.6 6.2 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPS25312.1 - 0.14 11.8 6.2 0.29 10.8 4.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EPS25312.1 - 0.9 9.1 9.0 7.2 6.2 4.1 2.7 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 EPS25312.1 - 2.8 8.0 7.2 5.5 7.0 5.0 1.5 1 0 0 1 1 1 0 RING-like domain PHD PF00628.24 EPS25312.1 - 5 6.8 7.0 9.4 6.0 4.9 1.5 1 0 0 1 1 1 0 PHD-finger LCM PF04072.9 EPS25313.1 - 3.1e-22 79.0 0.0 4.3e-22 78.5 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Na_H_Exchanger PF00999.16 EPS25314.1 - 5e-36 124.0 33.3 9.1e-36 123.1 23.1 1.3 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family SUN PF03856.8 EPS25315.1 - 6.2e-81 271.3 9.7 1e-80 270.6 6.7 1.3 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) adh_short PF00106.20 EPS25316.1 - 2.7e-10 40.4 0.1 4e-10 39.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPS25316.1 - 0.017 14.8 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPS25316.1 - 0.081 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 KR domain FMN_bind_2 PF04299.7 EPS25318.1 - 2e-53 180.3 0.1 2.4e-53 180.1 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain RFX1_trans_act PF04589.8 EPS25318.1 - 0.068 12.9 0.8 0.11 12.1 0.6 1.4 1 0 0 1 1 1 0 RFX1 transcription activation region Ist1 PF03398.9 EPS25319.1 - 3.8e-49 166.2 4.9 2.8e-23 82.1 3.7 2.4 2 1 1 3 3 3 2 Regulator of Vps4 activity in the MVB pathway Sigma70_ner PF04546.8 EPS25320.1 - 1 8.9 4.9 2.8 7.5 0.8 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Clat_adaptor_s PF01217.15 EPS25321.1 - 7.3e-56 187.8 2.0 8.4e-56 187.6 1.4 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Sulfotransfer_3 PF13469.1 EPS25322.1 - 0.00014 22.8 0.1 0.00027 21.9 0.0 1.3 1 1 0 1 1 1 1 Sulfotransferase family Arylsulfotran_2 PF14269.1 EPS25323.1 - 1.2e-58 198.6 6.4 1.6e-58 198.2 4.4 1.1 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EPS25323.1 - 1.6e-16 59.8 7.3 1.1e-14 53.7 5.0 2.9 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) MFS_1 PF07690.11 EPS25325.1 - 4.5e-15 55.2 47.3 2.9e-14 52.5 11.3 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TP_methylase PF00590.15 EPS25327.1 - 1.9e-21 76.7 0.2 3.3e-21 75.9 0.1 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases TFIID-18kDa PF02269.11 EPS25328.1 - 3.5e-25 87.6 0.3 3.5e-24 84.4 0.1 2.2 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit OCIA PF07051.6 EPS25328.1 - 0.14 11.5 1.7 0.32 10.4 1.2 1.5 1 0 0 1 1 1 0 Ovarian carcinoma immunoreactive antigen (OCIA) Pyridox_oxidase PF01243.15 EPS25329.1 - 2e-08 34.0 0.0 3.5e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase F-box-like PF12937.2 EPS25330.1 - 4.4e-05 23.1 0.0 8.8e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EPS25330.1 - 0.0007 19.1 0.6 0.0036 16.9 0.0 2.2 2 0 0 2 2 2 1 F-box domain zf-C2H2_jaz PF12171.3 EPS25331.1 - 3.1e-07 30.3 0.4 4.9e-07 29.7 0.3 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EPS25331.1 - 2.9e-05 24.0 0.4 4.6e-05 23.4 0.3 1.3 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EPS25331.1 - 0.019 15.2 0.4 0.036 14.3 0.3 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF3632 PF12311.3 EPS25331.1 - 0.52 10.0 5.1 7.3 6.3 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3632) MAP7 PF05672.6 EPS25331.1 - 0.74 9.1 27.9 2.2 7.6 13.3 2.2 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family BIR PF00653.16 EPS25332.1 - 4.6e-44 148.6 5.8 4.2e-23 81.5 0.1 2.5 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain DUF3525 PF12039.3 EPS25332.1 - 4.6 5.6 7.9 1.7 7.0 3.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3525) Mmp37 PF09139.6 EPS25333.1 - 2.3e-138 460.7 0.0 2.8e-138 460.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 Aminotran_1_2 PF00155.16 EPS25334.1 - 1.8e-62 211.3 0.0 2.3e-62 211.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EPS25334.1 - 0.033 12.4 0.1 0.07 11.4 0.0 1.5 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Flavi_glycoprot PF00869.15 EPS25336.1 - 0.018 14.0 0.0 0.025 13.5 0.0 1.1 1 0 0 1 1 1 0 Flavivirus glycoprotein, central and dimerisation domains RNA_pol_Rpb5_C PF01191.14 EPS25337.1 - 1.5e-35 120.5 0.2 3.1e-35 119.5 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 EPS25337.1 - 1.2e-31 108.9 0.0 1.9e-31 108.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Occludin_ELL PF07303.8 EPS25338.1 - 0.043 14.5 33.2 0.12 13.0 6.2 4.5 2 1 1 4 4 4 0 Occludin homology domain CENP-F_leu_zip PF10473.4 EPS25338.1 - 6.5 6.6 51.8 0.039 13.8 4.6 4.8 2 2 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CYSTM PF12734.2 EPS25340.1 - 0.29 11.2 69.2 2.1 8.5 27.4 5.4 1 1 1 2 2 2 0 Cysteine-rich TM module stress tolerance DUF1517 PF07466.6 EPS25340.1 - 8 5.3 5.6 9.1 5.1 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) HHH_3 PF12836.2 EPS25342.1 - 0.068 13.1 0.0 0.098 12.6 0.0 1.2 1 0 0 1 1 1 0 Helix-hairpin-helix motif Alpha-L-AF_C PF06964.7 EPS25343.1 - 3.8e-39 134.2 0.0 6.3e-39 133.5 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus CBM_4_9 PF02018.12 EPS25343.1 - 0.054 13.5 2.4 0.33 10.9 0.9 2.7 2 1 0 2 2 2 0 Carbohydrate binding domain NmrA PF05368.8 EPS25345.1 - 7.6e-17 61.3 0.0 1.2e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPS25345.1 - 5.4e-14 52.6 0.0 9.3e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EPS25345.1 - 1.3e-07 30.9 0.1 1.7e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 EPS25345.1 - 2.7e-05 23.7 0.1 4.3e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EPS25345.1 - 0.00014 22.1 0.1 0.00032 20.9 0.1 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EPS25345.1 - 0.00015 20.5 0.0 0.00024 19.9 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.15 EPS25345.1 - 0.00025 20.9 0.0 0.00046 20.0 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 EPS25345.1 - 0.0014 19.1 0.1 0.0023 18.4 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_4 PF07993.7 EPS25345.1 - 0.0014 17.5 0.8 0.012 14.5 0.1 2.2 2 0 0 2 2 2 1 Male sterility protein TrkA_N PF02254.13 EPS25345.1 - 0.012 15.5 0.1 0.029 14.3 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain KR PF08659.5 EPS25345.1 - 0.052 13.2 0.2 0.093 12.3 0.1 1.4 1 0 0 1 1 1 0 KR domain Ldh_1_N PF00056.18 EPS25345.1 - 0.091 12.5 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain adh_short PF00106.20 EPS25345.1 - 0.1 12.5 0.8 0.2 11.5 0.6 1.6 1 0 0 1 1 1 0 short chain dehydrogenase Zn_peptidase PF04228.8 EPS25345.1 - 0.12 11.5 0.1 0.52 9.4 0.0 1.9 1 1 1 2 2 2 0 Putative neutral zinc metallopeptidase MFS_1 PF07690.11 EPS25346.1 - 5.1e-33 114.2 25.4 5.1e-33 114.2 17.6 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily VirB3 PF05101.8 EPS25346.1 - 0.19 11.7 4.2 0.14 12.1 0.9 2.4 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein adh_short PF00106.20 EPS25347.1 - 3.4e-17 62.8 0.9 5.4e-17 62.2 0.6 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPS25347.1 - 6.8e-09 35.6 0.6 9.9e-09 35.1 0.4 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPS25347.1 - 7.1e-08 32.1 0.1 9.3e-08 31.7 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EPS25347.1 - 1.6e-06 28.2 0.2 2.7e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 EPS25347.1 - 0.00011 22.0 0.3 0.00024 20.9 0.2 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Acetate_kinase PF00871.12 EPS25347.1 - 0.09 11.3 0.1 0.13 10.8 0.1 1.1 1 0 0 1 1 1 0 Acetokinase family DUF641 PF04859.7 EPS25347.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) AA_permease PF00324.16 EPS25348.1 - 2.2e-104 349.4 44.1 2.5e-104 349.2 30.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPS25348.1 - 6.2e-28 97.4 46.9 8.1e-28 97.1 32.5 1.1 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_35 PF01301.14 EPS25349.1 - 8.7e-93 311.1 0.0 1.3e-92 310.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 EPS25349.1 - 8.7e-70 233.7 1.6 1.3e-68 229.9 0.4 2.2 2 0 0 2 2 2 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 EPS25349.1 - 1.6e-55 186.0 10.8 7.7e-29 100.2 3.1 2.9 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 EPS25349.1 - 2.9e-27 93.8 0.0 7.1e-27 92.6 0.0 1.7 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 Glyco_hydro_2_N PF02837.13 EPS25349.1 - 2.6e-08 33.6 0.2 6e-08 32.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Fve PF09259.6 EPS25349.1 - 0.019 14.8 0.1 0.071 13.0 0.1 1.9 1 0 0 1 1 1 0 Fungal immunomodulatory protein Fve Nol1_Nop2_Fmu PF01189.12 EPS25350.1 - 3.1e-29 102.2 0.0 1.7e-19 70.3 0.0 4.5 2 1 2 4 4 4 3 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 EPS25350.1 - 0.0055 16.7 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Peptidase_M16 PF00675.15 EPS25351.1 - 6.2e-57 191.5 0.1 1.2e-56 190.5 0.1 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EPS25351.1 - 8.8e-41 139.5 0.0 7e-39 133.4 0.0 2.2 2 0 0 2 2 2 2 Peptidase M16 inactive domain Epimerase PF01370.16 EPS25352.1 - 2.8e-21 76.0 0.0 3.5e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPS25352.1 - 2.2e-14 52.8 0.0 2.7e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EPS25352.1 - 1.3e-06 28.4 0.0 2.4e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EPS25352.1 - 9.3e-06 24.7 0.0 1.4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EPS25352.1 - 2e-05 24.6 0.0 2.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EPS25352.1 - 6e-05 22.1 0.1 0.0012 17.8 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 EPS25352.1 - 0.0027 17.4 0.0 0.0044 16.6 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EPS25352.1 - 0.011 14.6 0.0 0.034 13.0 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Soyouz_module PF14313.1 EPS25352.1 - 0.052 13.1 0.1 0.53 9.8 0.0 2.2 2 0 0 2 2 2 0 N-terminal region of Paramyxovirinae phosphoprotein (P) Semialdhyde_dh PF01118.19 EPS25352.1 - 0.077 13.3 0.2 0.2 11.9 0.1 1.7 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Fibrillarin PF01269.12 EPS25353.1 - 8.4e-106 352.0 0.0 9.7e-106 351.8 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EPS25353.1 - 7.3e-06 25.6 0.0 1.3e-05 24.8 0.0 1.3 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 EPS25353.1 - 0.0023 17.5 0.1 0.0034 16.9 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF3455 PF11937.3 EPS25354.1 - 3.8e-44 150.7 0.1 5e-44 150.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) DUF2990 PF11693.3 EPS25354.1 - 5.9e-19 67.6 1.0 2.1e-18 65.9 0.7 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF2990) CASP_C PF08172.7 EPS25355.1 - 4.1e-85 284.7 1.3 4.1e-85 284.7 0.9 3.9 3 1 1 4 4 4 1 CASP C terminal NOPS PF08075.6 EPS25355.1 - 0.048 14.0 0.8 0.18 12.2 0.0 2.2 2 0 0 2 2 2 0 NOPS (NUC059) domain Vps39_2 PF10367.4 EPS25356.1 - 6.1e-06 26.3 0.0 2e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 EPS25356.1 - 0.043 13.8 0.1 0.33 10.9 0.0 2.4 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 LSM PF01423.17 EPS25357.1 - 6.8e-20 70.3 0.1 8.9e-20 70.0 0.1 1.2 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.1 EPS25357.1 - 0.0043 17.4 5.4 0.0069 16.8 3.7 1.4 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 Zn_clus PF00172.13 EPS25358.1 - 0.039 13.8 9.7 0.086 12.7 6.8 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Dioxygenase_C PF00775.16 EPS25359.1 - 1.8e-52 177.2 0.0 2.6e-52 176.7 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EPS25359.1 - 1.9e-17 62.9 0.0 3.5e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EPS25359.1 - 0.02 14.9 0.0 0.056 13.4 0.0 1.8 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain Pkinase PF00069.20 EPS25360.1 - 4.5e-08 32.5 0.0 6.9e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS25360.1 - 0.0046 16.0 0.0 0.0071 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Auxin_resp PF06507.8 EPS25360.1 - 0.053 13.3 0.0 4.8 7.1 0.0 3.0 3 1 0 3 3 3 0 Auxin response factor UBA_4 PF14555.1 EPS25361.1 - 2.4e-11 42.9 0.0 4.5e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 EPS25361.1 - 1.3e-10 41.1 0.0 2.4e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 UBX domain DDRGK PF09756.4 EPS25361.1 - 2.9 7.2 14.2 4.7 6.5 9.9 1.2 1 0 0 1 1 1 0 DDRGK domain Seryl_tRNA_N PF02403.17 EPS25361.1 - 7 6.7 11.1 7.5 6.6 6.9 1.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ABC2_membrane PF01061.19 EPS25362.1 - 1.3e-93 312.0 62.5 4.5e-49 166.4 16.7 3.4 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 EPS25362.1 - 6.6e-41 138.1 5.3 6e-36 122.2 0.0 3.4 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.22 EPS25362.1 - 1.2e-37 129.2 0.0 7.3e-18 65.1 0.0 2.9 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.1 EPS25362.1 - 1.6e-23 82.5 0.1 7.9e-23 80.3 0.0 2.1 2 0 0 2 2 2 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EPS25362.1 - 6e-07 29.0 0.1 0.0004 19.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EPS25362.1 - 8.8e-06 24.9 0.1 0.00083 18.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EPS25362.1 - 2.6e-05 24.2 0.5 0.00067 19.6 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EPS25362.1 - 6.3e-05 22.8 0.1 0.0079 16.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 EPS25362.1 - 0.00021 20.4 18.6 0.00021 20.4 12.9 3.1 2 1 1 3 3 3 1 ABC-2 family transporter protein AAA_29 PF13555.1 EPS25362.1 - 0.00061 19.2 1.4 0.019 14.4 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 EPS25362.1 - 0.0023 17.3 0.4 0.019 14.3 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EPS25362.1 - 0.003 17.7 0.1 1 9.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EPS25362.1 - 0.006 15.8 0.0 0.47 9.6 0.0 3.1 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 EPS25362.1 - 0.0092 16.2 0.0 0.48 10.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EPS25362.1 - 0.01 16.0 0.1 4.1 7.6 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_21 PF13304.1 EPS25362.1 - 0.013 15.4 0.0 2.3 8.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EPS25362.1 - 0.026 15.3 0.0 0.68 10.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EPS25362.1 - 0.03 13.9 2.1 3.2 7.3 0.2 3.1 3 0 0 3 3 3 0 NACHT domain OmpH PF03938.9 EPS25362.1 - 0.053 13.4 1.0 20 5.0 0.0 3.1 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Miro PF08477.8 EPS25362.1 - 0.057 13.9 0.0 9.1 6.8 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein UPF0079 PF02367.12 EPS25362.1 - 0.062 12.9 0.9 9.8 5.8 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 FtsK_SpoIIIE PF01580.13 EPS25362.1 - 0.081 12.3 0.3 0.8 9.1 0.1 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family PDR_assoc PF08370.6 EPS25362.1 - 0.5 9.9 6.3 1.6 8.2 0.1 3.5 3 0 0 3 3 3 0 Plant PDR ABC transporter associated zf-C2H2 PF00096.21 EPS25364.1 - 3.7e-07 30.1 4.6 7.6e-05 22.8 0.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPS25364.1 - 0.024 14.9 0.1 0.024 14.9 0.1 3.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EPS25364.1 - 0.063 13.5 2.0 9.5 6.6 0.3 2.8 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.1 EPS25364.1 - 0.11 12.8 0.1 0.11 12.8 0.1 3.0 2 1 1 3 3 3 0 Zinc-finger double domain Ferric_reduct PF01794.14 EPS25365.1 - 5.2e-22 78.2 10.0 1.5e-21 76.8 7.0 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EPS25365.1 - 8.7e-15 54.9 0.0 5.2e-09 36.1 0.0 2.3 1 1 1 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EPS25365.1 - 9.4e-13 47.9 0.1 4.9e-07 29.5 0.1 2.7 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.16 EPS25365.1 - 0.0071 16.8 0.0 0.032 14.8 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DUF4405 PF14358.1 EPS25365.1 - 0.29 11.3 12.5 2 8.6 3.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) adh_short PF00106.20 EPS25366.1 - 8e-29 100.6 0.1 1.5e-28 99.8 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPS25366.1 - 1e-19 71.2 0.0 1.4e-19 70.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPS25366.1 - 1.9e-10 40.7 0.3 3.8e-10 39.7 0.0 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EPS25366.1 - 1.1e-06 28.2 0.0 1.6e-06 27.7 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EPS25366.1 - 0.00021 21.3 0.7 0.0083 16.1 0.2 2.6 2 1 0 2 2 2 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EPS25366.1 - 0.0025 17.5 0.6 0.0045 16.7 0.4 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase F420_oxidored PF03807.12 EPS25366.1 - 0.0091 16.4 0.9 0.18 12.2 0.1 2.4 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent THF_DHG_CYH_C PF02882.14 EPS25366.1 - 0.015 14.3 0.4 0.048 12.7 0.1 1.8 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain RmlD_sub_bind PF04321.12 EPS25366.1 - 0.064 12.1 0.2 0.18 10.6 0.0 1.8 2 1 0 2 2 2 0 RmlD substrate binding domain ADH_zinc_N PF00107.21 EPS25366.1 - 0.064 12.7 0.1 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ApbA PF02558.11 EPS25366.1 - 0.065 12.6 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Glyco_transf_5 PF08323.6 EPS25366.1 - 0.11 12.0 0.0 0.33 10.4 0.0 1.7 2 0 0 2 2 2 0 Starch synthase catalytic domain Fungal_trans PF04082.13 EPS25367.1 - 2.6e-14 52.7 0.0 5.3e-14 51.7 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS25367.1 - 4.5e-06 26.4 9.8 7.8e-06 25.7 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 EPS25368.1 - 7.6e-29 100.7 0.2 9.8e-29 100.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPS25368.1 - 2.4e-21 76.6 0.1 2.9e-21 76.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPS25368.1 - 3.7e-13 49.5 0.2 5.9e-13 48.8 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPS25368.1 - 1.7e-07 30.9 0.3 2.8e-07 30.2 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EPS25368.1 - 0.0002 20.3 0.0 0.00028 19.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 EPS25368.1 - 0.00036 19.6 0.0 0.00048 19.2 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 EPS25368.1 - 0.00049 20.1 0.5 0.0041 17.1 0.3 2.4 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EPS25368.1 - 0.018 14.7 0.4 0.08 12.7 0.1 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DNA_gyraseA_C PF03989.8 EPS25368.1 - 0.057 12.7 0.0 0.15 11.4 0.0 1.9 1 1 0 1 1 1 0 DNA gyrase C-terminal domain, beta-propeller RmlD_sub_bind PF04321.12 EPS25368.1 - 0.058 12.2 0.2 0.16 10.8 0.1 1.6 1 1 0 1 1 1 0 RmlD substrate binding domain ACT_7 PF13840.1 EPS25368.1 - 0.08 12.4 0.0 0.23 11.0 0.0 1.7 1 0 0 1 1 1 0 ACT domain NAD_synthase PF02540.12 EPS25368.1 - 0.084 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 NAD synthase Gtr1_RagA PF04670.7 EPS25368.1 - 0.14 11.3 0.0 0.18 10.8 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region ADH_N PF08240.7 EPS25369.1 - 7.1e-27 93.3 1.0 1.2e-26 92.6 0.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPS25369.1 - 2.4e-13 49.7 0.0 4.7e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Saccharop_dh PF03435.13 EPS25369.1 - 0.019 13.9 1.4 0.042 12.8 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase ThiF PF00899.16 EPS25369.1 - 0.033 14.0 0.2 0.059 13.1 0.1 1.4 1 0 0 1 1 1 0 ThiF family ApbA PF02558.11 EPS25369.1 - 0.049 13.0 0.0 0.088 12.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 EPS25370.1 - 4.4e-56 188.8 0.0 5.8e-56 188.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EPS25370.1 - 1.4e-18 66.6 0.0 1.7e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EPS25370.1 - 0.0016 18.3 0.2 0.0045 16.8 0.1 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 EPS25370.1 - 0.037 13.8 0.0 0.081 12.7 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Ribosomal_L22 PF00237.14 EPS25371.1 - 1.7e-35 121.1 0.1 2.8e-35 120.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e HAD_2 PF13419.1 EPS25373.1 - 7.9e-32 110.8 0.0 1e-31 110.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPS25373.1 - 0.057 13.8 0.0 0.55 10.5 0.0 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase GAT PF03127.9 EPS25374.1 - 7.7e-13 48.2 0.1 1.9e-12 47.0 0.1 1.6 1 0 0 1 1 1 1 GAT domain VHS PF00790.14 EPS25374.1 - 0.00086 18.9 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 VHS domain Chitin_bind_3 PF03067.10 EPS25375.1 - 3.9e-19 69.6 1.1 5.5e-19 69.1 0.8 1.2 1 0 0 1 1 1 1 Chitin binding domain Serglycin PF04360.7 EPS25375.1 - 0.017 14.8 0.3 0.03 14.0 0.2 1.5 1 0 0 1 1 1 0 Serglycin NfrA_C PF13283.1 EPS25375.1 - 0.043 13.1 0.0 0.09 12.1 0.0 1.5 1 0 0 1 1 1 0 Bacteriophage N adsorption protein A C-term Cation_efflux PF01545.16 EPS25376.1 - 2.3e-26 92.5 7.0 2.9e-26 92.2 4.9 1.1 1 0 0 1 1 1 1 Cation efflux family Pectate_lyase_3 PF12708.2 EPS25377.1 - 7.5e-90 300.9 21.0 4.6e-71 239.5 5.2 2.9 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EPS25377.1 - 3.3e-07 29.6 2.5 0.0015 17.9 0.1 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Aminotran_1_2 PF00155.16 EPS25380.1 - 1e-12 47.7 0.0 1.3e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II S6PP_C PF08472.5 EPS25381.1 - 0.19 11.3 0.0 0.38 10.3 0.0 1.4 1 0 0 1 1 1 0 Sucrose-6-phosphate phosphohydrolase C-terminal Ank_2 PF12796.2 EPS25382.1 - 7e-59 196.1 1.9 5.7e-21 74.6 0.0 4.8 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 EPS25382.1 - 1.6e-58 191.7 6.0 1.6e-10 40.2 0.1 8.6 8 1 1 9 9 9 7 Ankyrin repeat Ank_3 PF13606.1 EPS25382.1 - 5.6e-45 146.8 2.0 5.4e-06 26.1 0.0 9.7 9 0 0 9 9 9 6 Ankyrin repeat Ank_4 PF13637.1 EPS25382.1 - 1.3e-39 133.8 12.9 4.7e-13 49.2 0.3 7.3 3 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPS25382.1 - 5e-39 131.4 12.2 1e-08 35.1 0.1 7.7 2 2 5 7 7 7 6 Ankyrin repeats (many copies) CorA PF01544.13 EPS25382.1 - 1.9e-14 53.4 0.6 4.3e-14 52.2 0.4 1.6 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein GLE1 PF07817.8 EPS25382.1 - 1.9 7.3 5.6 0.15 11.0 0.2 1.7 2 0 0 2 2 2 0 GLE1-like protein PRP1_N PF06424.7 EPS25382.1 - 2.4 8.4 7.3 0.14 12.5 0.6 2.1 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Syntaxin PF00804.20 EPS25382.1 - 9.4 6.4 10.8 3.8 7.7 1.2 2.9 2 0 0 2 2 2 0 Syntaxin Kdo PF06293.9 EPS25384.1 - 2.2e-06 26.8 0.1 3.1e-06 26.4 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPS25384.1 - 3.6e-05 23.5 0.0 0.033 13.9 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 EPS25384.1 - 0.0064 15.6 0.0 0.008 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.15 EPS25384.1 - 0.019 14.5 0.0 3.8 7.0 0.0 2.2 1 1 1 2 2 2 0 Choline/ethanolamine kinase RIO1 PF01163.17 EPS25384.1 - 0.025 13.9 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 RIO1 family WaaY PF06176.6 EPS25384.1 - 0.061 12.5 0.0 0.087 12.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) FMN_dh PF01070.13 EPS25385.1 - 4.3e-104 348.1 0.0 5.9e-104 347.7 0.0 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EPS25385.1 - 6.5e-22 77.1 0.0 1.5e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EPS25385.1 - 6.1e-05 22.1 0.0 0.00016 20.7 0.0 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase IMPDH PF00478.20 EPS25385.1 - 0.00043 19.2 0.8 0.002 17.0 0.1 2.3 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain ATP11 PF06644.6 EPS25385.1 - 0.00097 18.7 0.1 0.0016 18.0 0.1 1.2 1 0 0 1 1 1 1 ATP11 protein NMO PF03060.10 EPS25385.1 - 0.12 11.4 0.4 0.48 9.5 0.0 2.0 1 1 1 2 2 2 0 Nitronate monooxygenase Fungal_trans_2 PF11951.3 EPS25386.1 - 5.3e-20 71.3 11.4 2.2e-18 66.0 7.9 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS25386.1 - 1.5e-05 24.7 11.0 3.4e-05 23.6 7.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhyH PF05721.8 EPS25387.1 - 2.1e-24 86.7 0.0 2.7e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) AA_permease PF00324.16 EPS25388.1 - 3.9e-137 457.4 46.7 4.7e-137 457.2 32.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPS25388.1 - 1.1e-35 123.0 53.3 1.3e-35 122.7 36.9 1.1 1 0 0 1 1 1 1 Amino acid permease MgtE PF01769.11 EPS25388.1 - 0.023 14.9 0.0 0.023 14.9 0.0 3.7 4 1 1 5 5 5 0 Divalent cation transporter AA_permease_C PF13906.1 EPS25388.1 - 0.027 14.3 1.8 0.027 14.3 1.2 3.5 3 0 0 3 3 3 0 C-terminus of AA_permease HSP20 PF00011.16 EPS25389.1 - 2e-08 33.9 0.1 2e-08 33.9 0.1 1.6 2 0 0 2 2 2 1 Hsp20/alpha crystallin family GRP PF07172.6 EPS25389.1 - 0.15 12.5 10.4 0.32 11.5 7.2 1.5 1 0 0 1 1 1 0 Glycine rich protein family Pyr_redox_2 PF07992.9 EPS25390.1 - 5.6e-27 94.9 0.0 2.6e-26 92.7 0.0 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPS25390.1 - 1.2e-10 41.6 0.0 5.8e-08 33.0 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPS25390.1 - 0.00024 21.2 0.0 0.57 10.2 0.0 3.9 3 1 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPS25390.1 - 0.028 14.4 0.0 6.7 6.8 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Amidase PF01425.16 EPS25391.1 - 1.6e-91 307.3 0.0 1.9e-91 307.1 0.0 1.1 1 0 0 1 1 1 1 Amidase adh_short PF00106.20 EPS25392.1 - 3.8e-27 95.2 1.4 5.3e-27 94.7 1.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPS25392.1 - 3.5e-23 82.6 0.2 4.6e-23 82.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPS25392.1 - 1.5e-11 44.2 0.6 2.3e-11 43.6 0.4 1.2 1 0 0 1 1 1 1 KR domain DUF3391 PF11871.3 EPS25392.1 - 0.00011 22.4 0.0 0.00022 21.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3391) Sod_Fe_N PF00081.17 EPS25393.1 - 3.6e-33 113.6 2.7 3.6e-33 113.6 1.9 1.9 2 1 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Sod_Fe_C PF02777.13 EPS25393.1 - 1.3e-32 111.7 0.2 2.6e-32 110.7 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain TFIID-31kDa PF02291.10 EPS25395.1 - 3.7e-31 107.5 0.0 1e-24 86.7 0.0 2.7 2 1 0 2 2 2 2 Transcription initiation factor IID, 31kD subunit Mucin PF01456.12 EPS25395.1 - 0.7 9.6 12.7 0.048 13.4 5.1 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein Cmc1 PF08583.5 EPS25396.1 - 2.7e-17 62.3 5.6 2.7e-17 62.3 3.9 1.7 1 1 1 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 EPS25396.1 - 0.047 13.6 0.1 0.13 12.2 0.0 1.8 1 1 0 1 1 1 0 CHCH domain DFF40 PF09230.5 EPS25396.1 - 0.42 9.9 5.8 0.53 9.6 4.0 1.2 1 0 0 1 1 1 0 DNA fragmentation factor 40 kDa Utp11 PF03998.8 EPS25397.1 - 7e-55 186.4 26.6 8.2e-55 186.2 18.4 1.0 1 0 0 1 1 1 1 Utp11 protein CIAPIN1 PF05093.8 EPS25398.1 - 2.4e-35 120.6 3.1 4.5e-35 119.7 2.1 1.4 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Histidinol_dh PF00815.15 EPS25399.1 - 1.8e-174 580.2 5.2 1.8e-174 580.2 3.6 1.6 2 0 0 2 2 2 1 Histidinol dehydrogenase PRA-CH PF01502.13 EPS25399.1 - 3e-25 87.6 0.1 6.7e-25 86.5 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 EPS25399.1 - 3e-09 37.0 0.2 9.1e-09 35.4 0.1 1.9 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase Glyco_hydro_47 PF01532.15 EPS25400.1 - 1.9e-135 452.0 0.0 2.1e-135 451.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 TPR_2 PF07719.12 EPS25401.1 - 1.7e-14 52.4 9.0 0.00015 21.3 0.1 5.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 EPS25401.1 - 4.8e-13 48.5 8.8 1.8e-06 27.4 0.1 4.6 4 1 1 5 5 5 2 TPR repeat TPR_1 PF00515.23 EPS25401.1 - 2.6e-09 36.2 10.5 0.003 17.0 0.0 5.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 EPS25401.1 - 1.5e-06 28.0 11.9 0.012 15.5 0.0 5.0 5 1 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 EPS25401.1 - 1.5e-05 25.5 8.9 0.0087 16.7 0.2 5.0 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EPS25401.1 - 0.00075 19.1 0.0 1.3 8.9 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EPS25401.1 - 0.0028 17.7 0.5 0.083 13.0 0.0 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EPS25401.1 - 0.003 17.6 4.1 23 5.5 0.0 5.9 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 EPS25401.1 - 0.0035 17.8 0.3 0.0035 17.8 0.2 6.1 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 EPS25401.1 - 0.0059 16.3 2.2 2.2 8.3 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EPS25401.1 - 0.0069 16.7 11.1 0.34 11.2 0.1 5.5 5 1 1 6 6 6 1 Tetratricopeptide repeat LNS2 PF08235.8 EPS25402.1 - 3.8e-71 237.7 0.0 6.6e-71 236.9 0.0 1.4 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 EPS25402.1 - 2e-40 136.8 0.0 7.1e-40 135.1 0.0 1.9 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 EPS25402.1 - 0.0015 17.9 0.0 0.071 12.4 0.0 2.8 3 0 0 3 3 3 1 HAD superfamily, subfamily IIIB (Acid phosphatase) fn3 PF00041.16 EPS25403.1 - 6.5e-07 29.4 0.0 1.8e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain DUF1635 PF07795.6 EPS25403.1 - 3.8 6.8 15.2 27 4.0 10.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) IncA PF04156.9 EPS25403.1 - 9.3 5.7 38.9 2.9 7.4 6.9 2.4 1 1 1 2 2 2 0 IncA protein Thg1C PF14413.1 EPS25404.1 - 1.3e-53 179.7 2.1 1.8e-53 179.3 1.5 1.1 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 EPS25404.1 - 7.2e-45 151.9 0.0 1e-44 151.4 0.0 1.2 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Peptidase_C48 PF02902.14 EPS25406.1 - 4.1e-14 52.7 0.4 2.3e-13 50.2 0.3 2.1 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain WH2 PF02205.15 EPS25407.1 - 1e-05 24.9 1.3 3.1e-05 23.4 0.9 1.8 1 0 0 1 1 1 1 WH2 motif LSM PF01423.17 EPS25408.1 - 4.4e-16 58.1 0.1 6e-16 57.7 0.1 1.2 1 0 0 1 1 1 1 LSM domain SURF4 PF02077.10 EPS25411.1 - 2.7e-94 315.4 7.1 3.1e-94 315.3 4.9 1.0 1 0 0 1 1 1 1 SURF4 family DoxX PF07681.7 EPS25411.1 - 0.44 10.9 19.1 0.34 11.3 3.1 3.3 3 2 0 3 3 3 0 DoxX PA26 PF04636.8 EPS25412.1 - 1 8.0 6.8 6.3 5.3 0.0 2.1 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) IU_nuc_hydro PF01156.14 EPS25414.1 - 5.3e-54 183.5 0.0 1.2e-53 182.4 0.0 1.5 1 1 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Transketolase_C PF02780.15 EPS25414.1 - 0.071 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Transketolase, C-terminal domain PAN_1 PF00024.21 EPS25415.1 - 0.42 10.4 4.8 0.15 11.8 0.4 2.1 1 1 1 2 2 2 0 PAN domain PAN_3 PF08277.7 EPS25415.1 - 0.64 9.6 2.7 1.4 8.6 0.2 2.1 1 1 1 2 2 2 0 PAN-like domain HLH PF00010.21 EPS25416.1 - 1.6e-14 53.2 0.2 3.4e-14 52.2 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain CTD PF12815.2 EPS25417.1 - 0.015 15.7 2.9 0.021 15.2 2.0 1.2 1 0 0 1 1 1 0 Spt5 C-terminal nonapeptide repeat binding Spt4 LAT PF15234.1 EPS25418.1 - 0.091 12.2 0.1 0.17 11.3 0.1 1.4 1 0 0 1 1 1 0 Linker for activation of T-cells DUF3147 PF11345.3 EPS25418.1 - 1.4 8.9 7.5 0.26 11.3 0.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3147) MFS_1 PF07690.11 EPS25419.1 - 1.5e-24 86.4 37.5 1.5e-17 63.4 5.8 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS25419.1 - 7.1e-09 34.7 1.7 7.1e-09 34.7 1.2 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EPS25419.1 - 1.8e-07 29.7 0.5 1.8e-07 29.7 0.3 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Zn_clus PF00172.13 EPS25421.1 - 1.2e-05 25.1 8.7 2.2e-05 24.2 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EPS25421.1 - 0.0027 16.6 0.5 0.0066 15.3 0.2 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain ABC_membrane PF00664.18 EPS25422.1 - 1.7e-70 237.6 25.9 2.1e-35 122.4 7.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EPS25422.1 - 7.3e-65 217.4 0.0 3.1e-31 108.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EPS25422.1 - 9.3e-14 51.1 4.2 0.00017 20.9 1.0 4.6 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EPS25422.1 - 5.6e-11 42.9 0.1 0.029 14.3 0.0 4.3 3 1 0 3 3 3 3 AAA domain AAA_16 PF13191.1 EPS25422.1 - 1.4e-09 38.2 3.0 1.7e-05 24.8 0.0 3.4 2 1 1 3 3 3 2 AAA ATPase domain ABC_ATPase PF09818.4 EPS25422.1 - 1.8e-08 33.4 0.9 0.0024 16.5 0.0 2.9 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 EPS25422.1 - 2.4e-08 33.3 0.2 0.005 16.3 0.0 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EPS25422.1 - 1.1e-07 32.0 0.5 0.35 11.0 0.0 4.2 3 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EPS25422.1 - 3.6e-06 27.7 0.0 0.079 13.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.12 EPS25422.1 - 3.5e-05 23.7 0.1 0.084 12.6 0.0 2.7 3 0 0 3 3 2 2 Domain of unknown function DUF87 DUF258 PF03193.11 EPS25422.1 - 5.8e-05 22.3 0.0 0.18 11.0 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 EPS25422.1 - 0.00022 20.7 0.4 0.77 9.1 0.0 3.4 3 1 1 4 4 4 2 AAA-like domain AAA_25 PF13481.1 EPS25422.1 - 0.00026 20.4 1.6 0.63 9.4 0.0 3.4 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EPS25422.1 - 0.00045 19.8 0.1 0.93 9.0 0.0 3.8 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.9 EPS25422.1 - 0.00063 19.4 0.0 3.2 7.4 0.0 4.1 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EPS25422.1 - 0.0015 18.4 0.0 0.44 10.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 EPS25422.1 - 0.0017 17.8 0.1 0.3 10.4 0.0 3.2 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_23 PF13476.1 EPS25422.1 - 0.0034 17.7 0.0 2.3 8.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 EPS25422.1 - 0.0039 17.0 7.0 0.5 10.3 0.1 4.1 4 2 0 4 4 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 EPS25422.1 - 0.0059 16.9 0.0 3.1 8.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EPS25422.1 - 0.021 14.5 0.1 3.4 7.3 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF3987 PF13148.1 EPS25422.1 - 0.024 13.2 0.0 5.7 5.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_28 PF13521.1 EPS25422.1 - 0.026 14.4 0.1 8.8 6.2 0.0 2.9 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.7 EPS25422.1 - 0.036 13.1 0.0 1.4 7.9 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin Rad17 PF03215.10 EPS25422.1 - 0.089 11.4 0.0 7.4 5.1 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_24 PF13479.1 EPS25422.1 - 0.11 12.0 0.0 9.2 5.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain RSV_NS2 PF03113.9 EPS25423.1 - 0.13 12.2 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Respiratory synctial virus non-structural protein NS2 CLASP_N PF12348.3 EPS25424.1 - 6.7e-146 483.6 0.3 1e-82 276.9 0.0 2.2 2 0 0 2 2 2 2 CLASP N terminal HEAT PF02985.17 EPS25424.1 - 8.1e-07 28.6 1.6 12 6.3 0.0 5.7 5 0 0 5 5 5 3 HEAT repeat Cnd1 PF12717.2 EPS25424.1 - 4.9e-06 26.5 0.1 0.0049 16.7 0.0 3.2 2 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EPS25424.1 - 3.5e-05 24.0 1.0 3.6 7.9 0.2 4.2 2 1 1 3 3 3 2 HEAT repeats Adaptin_N PF01602.15 EPS25424.1 - 0.025 12.9 0.5 0.088 11.1 0.0 2.0 2 1 0 2 2 2 0 Adaptin N terminal region Cohesin_HEAT PF12765.2 EPS25424.1 - 0.66 9.9 3.2 3.2 7.7 0.0 3.1 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion BSP PF04450.7 EPS25425.1 - 4.3e-70 235.3 0.0 5.1e-70 235.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 EPS25425.1 - 0.00053 20.0 0.0 0.0015 18.5 0.0 1.8 1 1 0 1 1 1 1 Peptidase MA superfamily SprT-like PF10263.4 EPS25425.1 - 0.006 16.2 0.1 0.0087 15.7 0.1 1.3 1 0 0 1 1 1 1 SprT-like family Ribonuclease_3 PF00636.21 EPS25426.1 - 2.2e-07 31.3 0.0 4.4e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EPS25426.1 - 5.2e-07 29.6 0.0 0.0035 17.2 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease-III-like dsrm PF00035.20 EPS25426.1 - 2.2e-05 24.9 0.0 5.1e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif PfkB PF00294.19 EPS25428.1 - 1.2e-12 47.5 0.0 4.4e-12 45.7 0.0 1.7 1 1 0 1 1 1 1 pfkB family carbohydrate kinase CAP_N PF01213.14 EPS25429.1 - 9.5e-81 271.4 19.6 2.9e-78 263.2 13.6 2.5 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 EPS25429.1 - 8.2e-57 191.0 1.2 1.1e-56 190.5 0.8 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 EPS25429.1 - 0.0036 16.6 2.3 0.093 12.1 1.0 2.2 1 1 1 2 2 2 1 Tubulin binding cofactor C Exonuc_VII_S PF02609.11 EPS25429.1 - 0.11 12.2 0.1 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Exonuclease VII small subunit P4Ha_N PF08336.6 EPS25429.1 - 0.12 12.2 0.1 5.1 6.9 0.0 2.9 2 1 1 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF2360 PF10152.4 EPS25429.1 - 1.7 8.9 17.9 0.076 13.2 0.7 3.0 2 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF4210 PF13915.1 EPS25430.1 - 2e-27 95.2 0.6 4.1e-27 94.2 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 EPS25430.1 - 6.1e-23 80.4 0.5 1.3e-22 79.3 0.4 1.6 1 0 0 1 1 1 1 Chromosome segregation during meiosis rRNA_processing PF08524.6 EPS25431.1 - 4.8 6.9 25.4 1.7e+02 1.9 17.6 2.1 1 1 0 1 1 1 0 rRNA processing RR_TM4-6 PF06459.7 EPS25431.1 - 5.8 6.7 9.8 7.5 6.3 6.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sec5 PF15469.1 EPS25432.1 - 1e-34 119.8 0.1 7.6e-34 117.0 0.0 2.5 3 0 0 3 3 3 1 Exocyst complex component Sec5 Vps51 PF08700.6 EPS25432.1 - 1.5e-06 27.9 0.7 4.7e-06 26.3 0.1 2.3 2 0 0 2 2 2 1 Vps51/Vps67 DUF445 PF04286.7 EPS25432.1 - 0.31 10.5 5.9 6.8 6.1 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF445) Iso_dh PF00180.15 EPS25433.1 - 5.1e-100 334.8 0.0 6.3e-100 334.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Eaf7 PF07904.8 EPS25434.1 - 1.6e-29 101.6 0.0 3e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 Nop14 PF04147.7 EPS25434.1 - 0.078 10.8 12.2 0.089 10.7 8.4 1.2 1 0 0 1 1 1 0 Nop14-like family PsbU PF06514.6 EPS25434.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Photosystem II 12 kDa extrinsic protein (PsbU) Daxx PF03344.10 EPS25434.1 - 4.3 5.7 12.9 6.3 5.1 8.9 1.2 1 0 0 1 1 1 0 Daxx Family Spc97_Spc98 PF04130.8 EPS25435.1 - 7.8e-80 268.7 1.2 9.9e-80 268.3 0.8 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family Mo-co_dimer PF03404.11 EPS25436.1 - 1.7e-55 186.2 0.0 3e-55 185.3 0.0 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 EPS25436.1 - 1.6e-48 164.3 0.0 2.7e-48 163.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.19 EPS25436.1 - 1.2e-30 105.4 0.0 2.3e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EPS25436.1 - 1.3e-25 90.0 0.0 2.8e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 EPS25436.1 - 1.8e-20 72.4 0.0 3.7e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 EPS25436.1 - 0.0026 17.6 0.1 0.36 10.7 0.0 2.3 1 1 1 2 2 2 1 Ferric reductase NAD binding domain NIR_SIR PF01077.17 EPS25437.1 - 1.2e-31 109.2 0.1 2.8e-31 108.0 0.0 1.6 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox_2 PF07992.9 EPS25437.1 - 8.6e-26 91.0 0.4 4.1e-25 88.8 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 EPS25437.1 - 5.1e-16 58.2 0.0 1e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Pyr_redox PF00070.22 EPS25437.1 - 3.8e-15 56.0 4.3 6.4e-15 55.3 0.4 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 EPS25437.1 - 8.9e-14 50.8 0.1 4.1e-13 48.7 0.0 2.1 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain Fer2_BFD PF04324.10 EPS25437.1 - 2.8e-13 49.6 3.4 1.1e-12 47.7 2.3 2.2 2 0 0 2 2 2 1 BFD-like [2Fe-2S] binding domain NIR_SIR_ferr PF03460.12 EPS25437.1 - 1.5e-09 37.3 0.0 3.4e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Pyr_redox_3 PF13738.1 EPS25437.1 - 3.7e-05 23.8 0.0 0.021 14.9 0.0 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DUF3255 PF11631.3 EPS25437.1 - 0.0059 16.2 0.1 0.2 11.3 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3255) NAD_binding_9 PF13454.1 EPS25437.1 - 0.0066 16.2 1.2 3.5 7.3 0.1 3.4 3 1 1 4 4 4 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EPS25437.1 - 0.024 13.5 0.0 0.87 8.4 0.0 2.4 1 1 1 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 EPS25437.1 - 0.075 13.2 0.1 0.85 9.9 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_2 PF00890.19 EPS25437.1 - 0.11 11.3 0.5 0.41 9.4 0.0 2.1 3 0 0 3 3 3 0 FAD binding domain MFS_1 PF07690.11 EPS25438.1 - 2.2e-27 95.7 27.3 2.2e-27 95.7 19.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF718 PF05336.8 EPS25439.1 - 7.6e-35 118.9 0.1 8.5e-35 118.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF718) His_Phos_1 PF00300.17 EPS25440.1 - 3.8e-28 98.5 0.0 5.5e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF1676 PF07898.8 EPS25440.1 - 0.006 16.8 0.0 0.0095 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1676) GNAT_acetyltr_2 PF13718.1 EPS25440.1 - 0.018 14.3 0.0 0.027 13.7 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 DUF4575 PF15143.1 EPS25440.1 - 0.11 12.2 4.0 0.78 9.4 2.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4575) Ribosomal_L18p PF00861.17 EPS25441.1 - 5e-42 142.8 0.2 5e-42 142.8 0.2 1.6 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EPS25441.1 - 1.4e-33 115.3 9.3 1.4e-33 115.3 6.5 1.7 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Metal_resist PF13801.1 EPS25441.1 - 0.089 12.7 0.1 0.22 11.5 0.1 1.6 1 0 0 1 1 1 0 Heavy-metal resistance HAD_2 PF13419.1 EPS25442.1 - 2.4e-17 63.7 0.0 3.7e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EPS25442.1 - 3.2e-05 23.5 0.0 5.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.2 EPS25442.1 - 0.049 13.2 0.0 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 Acid Phosphatase DUF3728 PF12528.3 EPS25442.1 - 0.1 13.0 0.1 0.41 11.0 0.0 1.9 2 0 0 2 2 2 0 Prepilin peptidase dependent protein C (DUF3728) Hydrolase PF00702.21 EPS25442.1 - 0.12 12.7 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase FTA4 PF13093.1 EPS25443.1 - 4.4e-67 225.6 3.9 5.1e-67 225.4 2.7 1.0 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Cob_adeno_trans PF01923.13 EPS25443.1 - 0.0091 15.7 0.2 0.065 13.0 0.1 2.2 1 1 0 1 1 1 1 Cobalamin adenosyltransferase Transcrip_act PF04949.8 EPS25443.1 - 0.059 12.9 0.2 0.13 11.8 0.1 1.5 1 1 0 1 1 1 0 Transcriptional activator Mnd1 PF03962.10 EPS25443.1 - 0.11 12.1 2.1 0.26 10.9 1.5 1.6 1 1 0 1 1 1 0 Mnd1 family LRR_6 PF13516.1 EPS25445.1 - 0.00042 20.0 5.0 46 4.5 0.1 6.7 6 0 0 6 6 6 0 Leucine Rich repeat LRR_4 PF12799.2 EPS25445.1 - 0.012 15.1 11.0 0.79 9.4 0.8 5.6 6 1 1 7 7 7 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EPS25445.1 - 0.46 10.9 8.1 30 5.4 0.0 5.6 6 0 0 6 6 6 0 Leucine rich repeat LRR_1 PF00560.28 EPS25445.1 - 0.63 10.2 9.1 21 5.6 0.0 6.2 6 1 0 6 6 6 0 Leucine Rich Repeat ABC_tran PF00005.22 EPS25450.1 - 6.2e-51 172.2 0.4 5e-28 98.1 0.2 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EPS25450.1 - 2e-22 79.9 32.7 9.9e-17 61.2 9.0 2.9 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_21 PF13304.1 EPS25450.1 - 6.1e-11 42.8 0.0 0.0064 16.4 0.0 4.3 3 1 1 4 4 4 3 AAA domain SMC_N PF02463.14 EPS25450.1 - 6e-09 35.4 5.8 0.0015 17.8 1.8 4.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EPS25450.1 - 6.6e-09 35.9 1.0 0.0048 17.0 0.0 3.6 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EPS25450.1 - 5.2e-08 33.0 0.1 0.0071 16.3 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EPS25450.1 - 5.9e-07 28.8 1.2 0.002 17.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA PF00004.24 EPS25450.1 - 2.3e-06 27.8 0.3 0.039 14.1 0.0 3.2 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EPS25450.1 - 3.3e-06 26.9 0.7 0.058 13.0 0.0 3.7 3 1 0 3 3 3 2 Archaeal ATPase AAA_29 PF13555.1 EPS25450.1 - 5.2e-06 25.8 3.4 0.047 13.2 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EPS25450.1 - 1.8e-05 24.6 1.9 0.077 12.9 0.3 3.1 2 1 0 2 2 2 2 50S ribosome-binding GTPase T2SE PF00437.15 EPS25450.1 - 2.4e-05 23.3 1.5 0.043 12.7 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein Miro PF08477.8 EPS25450.1 - 2.5e-05 24.7 0.5 0.11 13.0 0.1 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_33 PF13671.1 EPS25450.1 - 8.5e-05 22.4 0.5 0.18 11.6 0.0 2.7 2 1 0 2 2 2 2 AAA domain NB-ARC PF00931.17 EPS25450.1 - 0.0001 21.2 0.0 0.042 12.6 0.0 2.6 2 1 0 2 2 2 1 NB-ARC domain Zeta_toxin PF06414.7 EPS25450.1 - 0.0006 18.9 0.5 0.39 9.7 0.0 3.4 3 0 0 3 3 3 1 Zeta toxin Mg_chelatase PF01078.16 EPS25450.1 - 0.00061 19.0 0.1 0.72 8.9 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI SbcCD_C PF13558.1 EPS25450.1 - 0.00069 19.4 0.3 0.77 9.7 0.0 3.0 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 EPS25450.1 - 0.00077 18.9 2.5 0.21 10.9 0.0 3.0 3 0 0 3 3 3 1 AAA-like domain RNA_helicase PF00910.17 EPS25450.1 - 0.00087 19.4 0.1 0.71 10.0 0.0 3.5 3 0 0 3 3 2 1 RNA helicase AAA_23 PF13476.1 EPS25450.1 - 0.001 19.4 1.5 0.81 9.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 EPS25450.1 - 0.0011 18.4 1.5 0.33 10.4 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 EPS25450.1 - 0.0014 18.3 2.6 1.1 9.0 0.1 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 EPS25450.1 - 0.0014 18.2 0.1 0.31 10.5 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EPS25450.1 - 0.0016 18.0 1.9 1.8 8.0 0.1 3.2 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.1 EPS25450.1 - 0.0027 17.3 0.6 0.23 10.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EPS25450.1 - 0.0028 18.4 0.1 3.4 8.5 0.0 3.1 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EPS25450.1 - 0.003 17.0 4.7 0.47 9.8 0.5 2.6 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 EPS25450.1 - 0.0032 17.7 0.1 2.5 8.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EPS25450.1 - 0.0034 16.8 0.2 0.65 9.4 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family NACHT PF05729.7 EPS25450.1 - 0.0042 16.7 3.9 0.64 9.6 0.1 3.1 4 0 0 4 4 2 1 NACHT domain Septin PF00735.13 EPS25450.1 - 0.0046 16.0 1.4 0.11 11.4 0.1 2.2 2 0 0 2 2 2 1 Septin AAA_25 PF13481.1 EPS25450.1 - 0.0049 16.3 0.2 2.6 7.4 0.1 2.5 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 EPS25450.1 - 0.0049 16.6 1.0 0.47 10.2 0.0 2.4 2 0 0 2 2 2 1 Dynamin family AAA_14 PF13173.1 EPS25450.1 - 0.0051 16.7 0.5 0.22 11.4 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_5 PF07728.9 EPS25450.1 - 0.0058 16.3 1.2 2.8 7.6 0.1 3.3 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) UPF0079 PF02367.12 EPS25450.1 - 0.0076 15.8 1.3 0.77 9.4 0.1 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Adeno_IVa2 PF02456.10 EPS25450.1 - 0.013 14.2 0.1 0.048 12.3 0.0 1.8 2 0 0 2 2 2 0 Adenovirus IVa2 protein Viral_helicase1 PF01443.13 EPS25450.1 - 0.017 14.6 0.9 1.8 8.0 0.0 3.0 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 EPS25450.1 - 0.025 14.0 0.8 0.74 9.2 0.0 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase GTP_EFTU PF00009.22 EPS25450.1 - 0.04 13.3 0.2 2.4 7.5 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Sigma54_activat PF00158.21 EPS25450.1 - 0.06 12.8 0.0 8.7 5.7 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 EPS25450.1 - 0.063 12.6 1.5 15 4.9 0.0 3.8 4 0 0 4 4 4 0 IstB-like ATP binding protein DUF87 PF01935.12 EPS25450.1 - 0.068 12.9 3.8 0.19 11.5 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 ATP-synt_ab PF00006.20 EPS25450.1 - 0.083 12.3 0.9 9.4 5.6 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF815 PF05673.8 EPS25450.1 - 0.11 11.4 0.1 9.4 5.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TrwB_AAD_bind PF10412.4 EPS25450.1 - 0.17 10.4 1.3 6 5.3 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Guanylate_kin PF00625.16 EPS25450.1 - 0.23 10.8 0.2 0.54 9.6 0.0 1.6 2 0 0 2 2 1 0 Guanylate kinase ABC_ATPase PF09818.4 EPS25450.1 - 0.29 9.6 2.2 12 4.3 0.1 3.1 3 0 0 3 3 3 0 Predicted ATPase of the ABC class NTPase_1 PF03266.10 EPS25450.1 - 0.32 10.6 6.4 2.6 7.7 0.2 2.8 3 0 0 3 3 2 0 NTPase Metallophos PF00149.23 EPS25451.1 - 0.0061 15.9 0.0 0.0063 15.9 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ABC_tran PF00005.22 EPS25452.1 - 2e-41 141.4 9.9 1.4e-20 73.9 0.1 3.9 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 EPS25452.1 - 7.9e-19 68.7 1.2 1.9e-07 31.3 0.0 3.7 3 1 0 3 3 3 3 AAA domain ABC_tran_2 PF12848.2 EPS25452.1 - 1.8e-09 37.3 3.7 1.8e-09 37.3 2.6 2.6 2 0 0 2 2 1 1 ABC transporter SMC_N PF02463.14 EPS25452.1 - 1.7e-08 33.9 4.7 0.003 16.8 0.2 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EPS25452.1 - 0.00022 20.7 3.4 0.0073 15.8 0.0 2.9 3 0 0 3 3 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EPS25452.1 - 0.00027 20.8 0.3 0.6 10.0 0.0 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase DUF87 PF01935.12 EPS25452.1 - 0.0004 20.2 0.4 0.0004 20.2 0.2 2.9 3 0 0 3 3 2 1 Domain of unknown function DUF87 AAA_17 PF13207.1 EPS25452.1 - 0.00053 20.7 5.9 0.034 14.9 0.0 3.9 4 2 0 4 4 4 1 AAA domain MobB PF03205.9 EPS25452.1 - 0.0012 18.5 2.0 0.9 9.2 0.1 3.2 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EPS25452.1 - 0.0017 17.5 3.3 0.8 8.8 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_28 PF13521.1 EPS25452.1 - 0.0024 17.8 3.7 0.4 10.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 EPS25452.1 - 0.0026 18.0 0.5 4.2 7.6 0.0 3.1 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EPS25452.1 - 0.0032 17.1 0.5 0.58 9.8 0.0 2.7 2 0 0 2 2 2 1 NACHT domain Miro PF08477.8 EPS25452.1 - 0.007 16.8 0.1 2.5 8.5 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein ArgK PF03308.11 EPS25452.1 - 0.01 14.6 1.1 2.4 6.8 0.1 2.4 2 0 0 2 2 2 2 ArgK protein AAA PF00004.24 EPS25452.1 - 0.016 15.4 1.7 1.1 9.5 0.0 3.4 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPS25452.1 - 0.044 13.9 6.5 1.2 9.3 0.0 3.8 3 2 0 3 3 3 0 AAA domain AAA_33 PF13671.1 EPS25452.1 - 0.049 13.5 6.9 1.1 9.1 0.2 4.0 3 1 0 3 3 3 0 AAA domain AAA_25 PF13481.1 EPS25452.1 - 0.079 12.3 1.1 2.7 7.3 0.0 3.6 4 0 0 4 4 4 0 AAA domain FtsK_SpoIIIE PF01580.13 EPS25452.1 - 0.12 11.8 2.3 1.4 8.3 0.1 3.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family RNA_helicase PF00910.17 EPS25452.1 - 0.15 12.2 0.4 3.3 7.9 0.0 2.5 2 0 0 2 2 2 0 RNA helicase SbcCD_C PF13558.1 EPS25452.1 - 0.18 11.7 2.8 6.4 6.7 0.0 3.6 3 1 0 3 3 3 0 Putative exonuclease SbcCD, C subunit PduV-EutP PF10662.4 EPS25452.1 - 0.28 10.6 2.0 9.2 5.7 0.2 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 EPS25452.1 - 2.1 7.6 6.7 6.9 6.0 0.5 2.9 3 1 0 3 3 3 0 AAA-like domain AAA_16 PF13191.1 EPS25452.1 - 3.6 7.5 12.7 11 6.0 3.8 3.4 2 2 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.1 EPS25452.1 - 6.9 6.9 30.1 0.4 10.9 6.6 4.3 4 1 0 4 4 3 0 AAA domain MoaC PF01967.16 EPS25456.1 - 5.7e-47 158.7 0.1 1.1e-46 157.9 0.1 1.5 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.8 EPS25456.1 - 2e-35 121.2 0.1 7.1e-35 119.4 0.0 1.9 1 1 1 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 EPS25456.1 - 2e-22 80.1 0.0 3.6e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EPS25456.1 - 0.00016 21.7 0.0 0.00032 20.8 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EPS25456.1 - 0.001 19.0 0.0 0.0025 17.8 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain DUF1454 PF07305.7 EPS25456.1 - 0.096 11.7 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1454) Noc2 PF03715.8 EPS25457.1 - 6.6e-124 412.6 0.0 6.6e-124 412.6 0.0 1.8 2 0 0 2 2 2 1 Noc2p family adh_short PF00106.20 EPS25457.1 - 0.033 14.1 0.1 0.093 12.6 0.0 1.8 1 0 0 1 1 1 0 short chain dehydrogenase VPS28 PF03997.7 EPS25458.1 - 1.3e-59 200.9 0.0 1.5e-59 200.7 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein DUF3262 PF11660.3 EPS25459.1 - 0.0015 18.5 1.7 0.0021 18.1 1.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3262) Methyltransf_16 PF10294.4 EPS25460.1 - 3.5e-22 78.6 0.0 7.2e-22 77.6 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 EPS25460.1 - 0.039 13.5 0.0 0.14 11.7 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EPS25460.1 - 0.056 14.0 0.0 0.12 12.9 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EPS25460.1 - 0.057 12.7 0.0 0.09 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DUF829 PF05705.9 EPS25461.1 - 9e-45 153.2 0.0 1e-44 153.0 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DEAD PF00270.24 EPS25463.1 - 2e-27 95.7 1.6 2e-26 92.5 0.0 2.8 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPS25463.1 - 4.9e-23 80.7 0.1 2.3e-22 78.6 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPS25463.1 - 1.1e-08 35.1 0.0 9.7e-08 32.0 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit PYC_OADA PF02436.13 EPS25463.1 - 0.024 14.0 0.9 0.053 12.9 0.6 1.5 1 0 0 1 1 1 0 Conserved carboxylase domain ATP-synt_G PF04718.10 EPS25464.1 - 1.7e-31 108.9 0.2 4.6e-31 107.5 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit ADH_N PF08240.7 EPS25465.1 - 6.5e-27 93.4 1.0 6.5e-27 93.4 0.7 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPS25465.1 - 8.9e-13 47.9 0.0 3.1e-12 46.1 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glyco_hydro_31 PF01055.21 EPS25467.1 - 5.7e-172 572.5 1.2 7e-172 572.1 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EPS25467.1 - 4.6e-10 39.2 1.3 1.4e-09 37.6 0.9 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like Glyco_hydro_16 PF00722.16 EPS25468.1 - 3.2e-42 143.8 4.0 3.2e-42 143.8 2.8 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 DUF4637 PF15470.1 EPS25468.1 - 0.37 10.3 2.7 0.56 9.8 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) tRNA-synt_2b PF00587.20 EPS25470.1 - 1.6e-48 164.5 0.0 2.2e-48 164.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EPS25470.1 - 9.7e-06 25.4 0.0 1.6e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain HMGL-like PF00682.14 EPS25471.1 - 5.9e-65 219.2 0.0 8.8e-65 218.6 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 EPS25471.1 - 1.4e-19 70.1 0.0 2.9e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain AMP-binding PF00501.23 EPS25472.1 - 1.9e-57 194.5 2.0 5.3e-32 110.7 0.0 4.6 3 2 0 3 3 3 3 AMP-binding enzyme DMAP_binding PF06464.6 EPS25472.1 - 7.4e-10 39.4 0.0 2.1e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 DMAP1-binding Domain GvpG PF05120.7 EPS25472.1 - 0.007 16.1 0.1 0.014 15.1 0.1 1.5 1 0 0 1 1 1 1 Gas vesicle protein G Ribosomal_S7 PF00177.16 EPS25473.1 - 1.2e-37 128.7 2.3 1.5e-37 128.4 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e SDA1 PF05285.7 EPS25474.1 - 8.1e-98 327.6 44.2 8.8e-98 327.5 25.4 2.2 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 EPS25474.1 - 6.7e-22 77.5 0.5 1.5e-21 76.3 0.3 1.7 1 0 0 1 1 1 1 NUC130/3NT domain RNR_inhib PF08591.5 EPS25475.1 - 3.5e-16 59.9 0.5 9e-16 58.5 0.1 1.9 2 0 0 2 2 2 1 Ribonucleotide reductase inhibitor p450 PF00067.17 EPS25476.1 - 1.1e-60 205.4 0.0 1.5e-60 205.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HSP70 PF00012.15 EPS25479.1 - 2e-62 211.0 4.8 1.6e-59 201.4 0.1 3.5 4 0 0 4 4 4 2 Hsp70 protein FAP PF07174.6 EPS25480.1 - 3.3 6.9 17.2 4 6.6 11.9 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Tubulin_3 PF14881.1 EPS25482.1 - 1.9e-87 291.3 0.8 2.8e-87 290.8 0.5 1.2 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 EPS25482.1 - 1e-43 148.0 0.1 1.2e-42 144.6 0.0 2.8 4 0 0 4 4 4 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 EPS25482.1 - 3.4e-06 27.0 0.0 0.019 14.8 0.0 2.2 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain Myosin_tail_1 PF01576.14 EPS25483.1 - 0.00028 18.7 29.4 0.00054 17.8 15.2 2.1 2 0 0 2 2 2 2 Myosin tail DUF1832 PF08870.6 EPS25483.1 - 0.055 13.1 0.1 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1832) ATG16 PF08614.6 EPS25483.1 - 0.35 10.6 26.4 0.96 9.2 10.4 3.3 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) DUF3584 PF12128.3 EPS25483.1 - 0.45 7.7 23.4 0.77 7.0 14.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Spc7 PF08317.6 EPS25483.1 - 0.52 8.9 15.8 0.23 10.0 8.6 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein Kinetocho_Slk19 PF12709.2 EPS25483.1 - 0.57 10.3 19.8 3.2 7.9 9.0 3.1 3 0 0 3 3 3 0 Central kinetochore-associated Atg14 PF10186.4 EPS25483.1 - 0.63 8.9 18.7 1.6 7.6 13.0 1.6 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 EPS25483.1 - 2.2 7.2 21.8 0.1 11.6 10.8 1.9 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF342 PF03961.8 EPS25483.1 - 4.8 5.4 12.1 5.3 5.3 7.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF342) DUF2347 PF09804.4 EPS25484.1 - 4.3e-104 347.7 0.0 5.9e-104 347.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 EPS25484.1 - 3.7e-59 199.7 0.4 5.6e-59 199.1 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) SPA PF08616.5 EPS25484.1 - 0.0037 16.9 0.0 0.0066 16.1 0.0 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 EPS25484.1 - 0.01 14.3 0.0 3.9 5.8 0.0 2.6 2 1 0 2 2 2 2 Transport protein Avl9 EBP PF05241.7 EPS25485.1 - 3.9e-66 221.7 11.3 4.6e-66 221.5 7.8 1.0 1 0 0 1 1 1 1 Emopamil binding protein PhageP22-tail PF09251.5 EPS25486.1 - 0.28 9.3 0.1 0.43 8.7 0.1 1.1 1 0 0 1 1 1 0 Salmonella phage P22 tail-spike SNF2_N PF00176.18 EPS25487.1 - 1.1e-65 221.3 0.0 1.6e-65 220.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPS25487.1 - 8.9e-12 44.7 0.0 2.8e-11 43.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPS25487.1 - 2.9e-05 23.9 0.0 7.4e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ETRAMP PF09716.5 EPS25487.1 - 0.025 14.5 0.2 0.079 12.9 0.1 1.9 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) AA_permease_2 PF13520.1 EPS25488.1 - 5.8e-49 166.7 55.0 7.2e-49 166.4 38.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPS25488.1 - 5.2e-20 71.2 46.9 1e-19 70.2 32.5 1.3 1 1 0 1 1 1 1 Amino acid permease DUF106 PF01956.11 EPS25489.1 - 1.3 8.5 7.0 2.5 7.5 0.2 2.4 2 0 0 2 2 2 0 Integral membrane protein DUF106 AAA_2 PF07724.9 EPS25491.1 - 3.6e-46 157.1 0.0 9.8e-45 152.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EPS25491.1 - 2.9e-28 98.7 0.3 8.1e-15 55.1 0.0 3.1 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EPS25491.1 - 4e-23 81.1 0.2 1.3e-22 79.5 0.1 1.9 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EPS25491.1 - 1.2e-15 57.4 0.0 1.7e-09 37.5 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EPS25491.1 - 2.1e-15 57.2 14.4 6.1e-06 26.3 0.0 6.4 3 2 3 6 6 5 2 AAA ATPase domain AAA_22 PF13401.1 EPS25491.1 - 1.6e-14 54.1 0.1 4.5e-05 23.5 0.0 3.8 2 2 1 3 3 3 2 AAA domain Sigma54_activat PF00158.21 EPS25491.1 - 8e-09 35.1 0.0 2.4e-05 23.8 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_17 PF13207.1 EPS25491.1 - 2.6e-08 34.6 4.2 0.0065 17.2 0.0 3.6 3 2 0 3 3 3 2 AAA domain IstB_IS21 PF01695.12 EPS25491.1 - 1.3e-07 31.2 0.0 0.018 14.4 0.0 2.8 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_18 PF13238.1 EPS25491.1 - 2.2e-07 31.2 0.5 0.017 15.4 0.0 3.7 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EPS25491.1 - 2.4e-07 30.4 0.0 0.018 14.7 0.0 3.2 3 1 0 3 3 2 2 Part of AAA domain AAA_14 PF13173.1 EPS25491.1 - 6.6e-07 29.2 0.0 0.042 13.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EPS25491.1 - 1.5e-05 24.2 0.0 0.14 11.3 0.0 3.4 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 EPS25491.1 - 3.4e-05 23.6 9.2 0.011 15.4 0.1 5.1 4 1 0 4 4 3 1 Archaeal ATPase RNA_helicase PF00910.17 EPS25491.1 - 6e-05 23.1 0.0 0.46 10.6 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.1 EPS25491.1 - 7.2e-05 22.8 2.9 0.27 11.2 0.0 3.6 3 1 0 3 3 2 2 AAA domain ABC_tran PF00005.22 EPS25491.1 - 8e-05 22.9 0.6 0.78 10.0 0.0 3.5 3 0 0 3 3 3 1 ABC transporter AAA_33 PF13671.1 EPS25491.1 - 8.1e-05 22.5 0.0 0.19 11.5 0.0 3.1 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 EPS25491.1 - 8.4e-05 21.5 0.0 0.0052 15.7 0.0 2.6 2 1 0 2 2 2 1 Type II/IV secretion system protein AAA_3 PF07726.6 EPS25491.1 - 0.00013 21.5 0.0 0.68 9.5 0.0 3.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EPS25491.1 - 0.00016 21.4 0.0 0.88 9.2 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EPS25491.1 - 0.00021 20.7 0.0 1.3 8.3 0.0 3.7 2 1 1 3 3 3 2 AAA domain Clp_N PF02861.15 EPS25491.1 - 0.00036 20.3 1.1 5.8 6.9 0.0 3.9 3 0 0 3 3 3 0 Clp amino terminal domain AAA_29 PF13555.1 EPS25491.1 - 0.00049 19.5 0.0 0.37 10.3 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 EPS25491.1 - 0.00088 18.5 0.0 0.4 9.8 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ResIII PF04851.10 EPS25491.1 - 0.001 18.9 0.0 0.43 10.3 0.0 3.5 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit NTPase_1 PF03266.10 EPS25491.1 - 0.0021 17.7 0.0 0.13 11.9 0.0 3.1 3 0 0 3 3 3 1 NTPase AAA_10 PF12846.2 EPS25491.1 - 0.0024 17.3 5.4 0.73 9.2 0.0 4.8 4 2 1 6 6 6 1 AAA-like domain AAA_24 PF13479.1 EPS25491.1 - 0.0037 16.8 0.0 2.1 7.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EPS25491.1 - 0.0051 16.4 0.0 0.4 10.3 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_21 PF13304.1 EPS25491.1 - 0.018 15.0 0.0 2.3 8.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 EPS25491.1 - 0.019 14.4 0.2 6.9 6.0 0.0 3.1 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain MMR_HSR1 PF01926.18 EPS25491.1 - 0.023 14.6 0.0 0.38 10.7 0.0 3.0 3 0 0 3 3 3 0 50S ribosome-binding GTPase Torsin PF06309.6 EPS25491.1 - 0.031 14.1 0.0 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 Torsin UPF0079 PF02367.12 EPS25491.1 - 0.048 13.2 0.0 12 5.5 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PduV-EutP PF10662.4 EPS25491.1 - 0.12 11.8 0.0 7.4 6.0 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 EPS25491.1 - 1.1 9.5 0.0 1.1 9.5 0.0 4.0 3 2 0 3 3 2 0 AAA domain APG6 PF04111.7 EPS25491.1 - 3.8 6.4 8.2 8.4 5.3 5.7 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 Viral_P18 PF04521.8 EPS25491.1 - 4.2 6.8 7.5 14 5.1 0.3 2.5 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein IncA PF04156.9 EPS25491.1 - 7.8 6.0 11.6 0.99 8.9 4.8 1.9 2 0 0 2 2 1 0 IncA protein ATG27 PF09451.5 EPS25494.1 - 7.5e-78 261.4 0.0 9e-78 261.1 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 EPS25494.1 - 2.8e-06 27.1 0.0 0.00021 21.0 0.0 2.6 3 0 0 3 3 3 1 Cation-independent mannose-6-phosphate receptor repeat Prefoldin_2 PF01920.15 EPS25495.1 - 8.5e-24 83.3 3.8 1e-23 83.0 2.7 1.1 1 0 0 1 1 1 1 Prefoldin subunit eIF-4B PF06273.6 EPS25495.1 - 0.037 12.7 1.4 0.046 12.4 1.0 1.0 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Nnf1 PF03980.9 EPS25495.1 - 0.057 13.4 2.7 0.09 12.7 1.9 1.4 1 1 0 1 1 1 0 Nnf1 AAA_23 PF13476.1 EPS25495.1 - 0.083 13.2 2.4 0.096 13.0 1.7 1.1 1 0 0 1 1 1 0 AAA domain TBPIP PF07106.8 EPS25495.1 - 0.092 12.2 5.2 0.25 10.8 0.0 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IFT57 PF10498.4 EPS25495.1 - 0.18 10.5 5.3 0.75 8.4 0.0 2.0 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF3338 PF11819.3 EPS25495.1 - 0.2 11.1 3.3 4.2 6.8 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3338) Spore_III_AF PF09581.5 EPS25495.1 - 0.2 11.4 3.7 0.38 10.5 2.6 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) UPF0242 PF06785.6 EPS25495.1 - 0.22 10.1 3.6 0.27 9.8 2.5 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) DASH_Spc19 PF08287.6 EPS25495.1 - 0.27 10.8 5.4 1.2 8.6 0.1 2.2 2 0 0 2 2 2 0 Spc19 Baculo_PEP_C PF04513.7 EPS25495.1 - 0.35 10.7 2.0 0.39 10.5 0.2 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.6 EPS25495.1 - 0.39 10.6 3.2 0.64 9.9 0.1 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) PilJ PF13675.1 EPS25495.1 - 0.63 10.3 4.0 6.6 7.0 0.9 2.1 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Adeno_PIX PF03955.9 EPS25495.1 - 0.88 10.1 4.1 8.7 6.9 0.1 2.1 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) CENP-Q PF13094.1 EPS25495.1 - 1.3 8.9 9.2 1.8 8.5 3.0 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit IncA PF04156.9 EPS25495.1 - 1.6 8.2 10.9 2.1 7.9 0.1 2.0 2 0 0 2 2 2 0 IncA protein DUF848 PF05852.6 EPS25495.1 - 2.2 8.1 10.9 3.6 7.4 2.2 2.8 2 1 1 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) KfrA_N PF11740.3 EPS25495.1 - 5.9 7.3 10.0 0.67 10.4 0.7 2.3 1 1 0 2 2 2 0 Plasmid replication region DNA-binding N-term DivIC PF04977.10 EPS25495.1 - 9.6 5.7 11.4 8.5 5.9 0.2 2.2 2 0 0 2 2 2 0 Septum formation initiator HSP70 PF00012.15 EPS25496.1 - 1.6e-10 39.5 0.4 5.6e-09 34.4 0.1 2.0 2 0 0 2 2 2 2 Hsp70 protein zf-SAP30 PF13866.1 EPS25496.1 - 0.016 14.8 0.1 0.038 13.6 0.1 1.5 1 0 0 1 1 1 0 SAP30 zinc-finger MreB_Mbl PF06723.8 EPS25496.1 - 0.046 12.3 0.1 0.33 9.5 0.0 2.0 2 0 0 2 2 2 0 MreB/Mbl protein N2227 PF07942.7 EPS25497.1 - 1.5e-88 296.2 0.0 2.1e-88 295.8 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein Methyltransf_11 PF08241.7 EPS25497.1 - 0.00014 22.2 0.0 0.00036 20.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPS25497.1 - 0.0002 21.1 0.0 0.00067 19.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPS25497.1 - 0.0029 18.0 0.0 0.012 16.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain HMG_CoA_synt_C PF08540.5 EPS25499.1 - 1.1e-97 326.9 0.4 2.4e-97 325.8 0.3 1.5 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EPS25499.1 - 7e-82 273.1 0.1 9.6e-82 272.7 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III_C PF08541.5 EPS25499.1 - 0.0081 16.1 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 EPS25499.1 - 0.046 13.3 0.1 0.087 12.4 0.1 1.4 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III NP1-WLL PF11733.3 EPS25500.1 - 0.027 14.7 0.0 0.03 14.5 0.0 1.1 1 0 0 1 1 1 0 Non-capsid protein NP1 Fungal_trans PF04082.13 EPS25503.1 - 1.1e-24 86.7 0.0 1.8e-24 86.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS25503.1 - 2.9e-06 27.0 12.2 7.3e-06 25.8 8.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S10 PF00450.17 EPS25504.1 - 8.8e-92 308.4 4.4 1.2e-91 308.0 3.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase BRCT PF00533.21 EPS25505.1 - 0.02 15.0 0.0 0.022 14.9 0.0 1.1 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain DUF4265 PF14085.1 EPS25505.1 - 0.052 13.3 0.0 0.056 13.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4265) Rnk_N PF14760.1 EPS25505.1 - 0.056 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Rnk N-terminus 4HBT_3 PF13622.1 EPS25506.1 - 5e-44 150.9 2.1 7.3e-44 150.4 1.4 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EPS25506.1 - 3.4e-26 91.4 0.0 2.3e-13 49.9 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase Succ_CoA_lig PF13607.1 EPS25506.1 - 0.15 11.7 0.0 1 8.9 0.0 2.3 3 0 0 3 3 3 0 Succinyl-CoA ligase like flavodoxin domain DUF3445 PF11927.3 EPS25507.1 - 1.2e-73 247.5 0.0 1.6e-73 247.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) BTB_2 PF02214.17 EPS25507.1 - 0.016 15.3 1.0 1.3 9.2 0.0 3.4 2 1 1 3 3 3 0 BTB/POZ domain MFS_1 PF07690.11 EPS25509.1 - 7.3e-33 113.7 35.5 7.3e-33 113.7 24.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS25509.1 - 1.5e-13 50.1 7.5 1.5e-13 50.1 5.2 2.1 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS25510.1 - 5e-26 91.2 50.3 1.3e-20 73.4 20.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS25510.1 - 2e-18 66.1 24.3 2.7e-18 65.8 16.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Mito_carr PF00153.22 EPS25511.1 - 3.2e-48 161.3 8.7 1.4e-17 63.2 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PT-VENN PF04829.8 EPS25511.1 - 0.03 13.8 0.3 0.074 12.6 0.2 1.7 1 0 0 1 1 1 0 Pre-toxin domain with VENN motif COesterase PF00135.23 EPS25512.1 - 3.8e-100 336.1 0.0 4.6e-100 335.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EPS25512.1 - 5.7e-10 39.1 1.1 3.3e-09 36.6 0.3 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold PAP_central PF04928.12 EPS25513.1 - 2.5e-105 350.8 0.0 3.3e-105 350.5 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EPS25513.1 - 6.3e-50 168.7 0.0 9.7e-50 168.1 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EPS25513.1 - 2.3e-08 34.2 0.0 8.6e-08 32.4 0.0 1.9 2 0 0 2 2 2 1 Nucleotidyltransferase domain Abhydrolase_1 PF00561.15 EPS25515.1 - 5.1e-12 45.8 0.1 2.1e-11 43.8 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EPS25515.1 - 2e-11 44.2 0.0 3e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EPS25515.1 - 0.00015 21.0 0.0 0.00035 19.8 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EPS25515.1 - 0.018 14.7 0.1 0.17 11.6 0.1 2.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.15 EPS25515.1 - 0.063 12.6 0.0 0.095 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Flavin_Reduct PF01613.13 EPS25516.1 - 3.7e-19 69.0 0.0 5.2e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain DUF447 PF04289.7 EPS25516.1 - 0.04 13.4 0.0 0.062 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF447) Nucleoplasmin PF03066.10 EPS25517.1 - 0.00019 20.9 7.4 0.00019 20.9 5.2 1.1 1 0 0 1 1 1 1 Nucleoplasmin RXT2_N PF08595.6 EPS25517.1 - 0.0014 18.4 1.2 0.0015 18.3 0.9 1.1 1 0 0 1 1 1 1 RXT2-like, N-terminal Sigma70_ner PF04546.8 EPS25517.1 - 0.0028 17.3 3.8 0.0028 17.2 2.7 1.1 1 0 0 1 1 1 1 Sigma-70, non-essential region Mak16 PF04874.9 EPS25517.1 - 0.003 17.6 11.0 0.004 17.1 7.6 1.2 1 0 0 1 1 1 1 Mak16 protein C-terminal region BSP_II PF05432.6 EPS25517.1 - 0.0052 16.1 12.6 0.0053 16.0 8.7 1.1 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) DUF4366 PF14283.1 EPS25517.1 - 0.01 15.2 1.5 0.011 15.2 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Tim54 PF11711.3 EPS25517.1 - 0.013 14.0 1.4 0.012 14.1 1.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PBP1_TM PF14812.1 EPS25517.1 - 0.025 14.8 2.0 0.03 14.6 1.4 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Drc1-Sld2 PF11719.3 EPS25517.1 - 0.026 13.6 0.9 0.026 13.6 0.6 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein NOA36 PF06524.7 EPS25517.1 - 0.026 13.7 0.7 0.026 13.7 0.5 1.2 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.7 EPS25517.1 - 0.038 11.9 7.9 0.042 11.7 5.5 1.0 1 0 0 1 1 1 0 Nop14-like family VID27 PF08553.5 EPS25517.1 - 0.041 12.1 7.6 0.044 12.0 5.3 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein CDV3 PF15359.1 EPS25517.1 - 0.044 13.8 5.1 0.058 13.4 3.5 1.2 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 GOLD_2 PF13897.1 EPS25517.1 - 0.053 13.7 2.4 0.056 13.6 1.6 1.1 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking AF1Q PF15017.1 EPS25517.1 - 0.057 13.3 7.1 0.08 12.8 4.9 1.3 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator Sporozoite_P67 PF05642.6 EPS25517.1 - 0.078 10.8 3.7 0.08 10.7 2.6 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RNA_pol_Rpc4 PF05132.9 EPS25517.1 - 0.09 12.7 1.7 0.09 12.7 1.2 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 RNase_H2_suC PF08615.6 EPS25517.1 - 0.11 12.3 0.9 0.11 12.2 0.6 1.1 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) CENP-B_dimeris PF09026.5 EPS25517.1 - 0.13 12.5 11.3 0.17 12.1 7.8 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CDC45 PF02724.9 EPS25517.1 - 0.16 10.0 4.6 0.17 9.8 3.2 1.0 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.11 EPS25517.1 - 0.24 10.3 6.0 0.28 10.1 4.2 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit HSP90 PF00183.13 EPS25517.1 - 0.25 9.6 8.9 0.29 9.4 6.1 1.0 1 0 0 1 1 1 0 Hsp90 protein Pox_Ag35 PF03286.9 EPS25517.1 - 0.29 10.6 6.3 0.34 10.4 4.3 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Ycf1 PF05758.7 EPS25517.1 - 0.32 8.6 3.1 0.28 8.8 2.2 1.0 1 0 0 1 1 1 0 Ycf1 FHIPEP PF00771.15 EPS25517.1 - 0.33 9.2 1.3 0.37 9.0 0.9 1.0 1 0 0 1 1 1 0 FHIPEP family DUF2457 PF10446.4 EPS25517.1 - 0.34 9.5 10.7 0.38 9.4 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) E7 PF00527.13 EPS25517.1 - 0.39 10.8 2.5 0.57 10.3 1.7 1.3 1 0 0 1 1 1 0 E7 protein, Early protein FAM176 PF14851.1 EPS25517.1 - 0.44 10.2 6.2 0.56 9.8 4.3 1.2 1 0 0 1 1 1 0 FAM176 family DUF3899 PF13038.1 EPS25517.1 - 0.44 10.7 1.6 0.63 10.2 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) OAD_gamma PF04277.8 EPS25517.1 - 0.48 10.8 1.7 0.62 10.4 1.2 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Myc_N PF01056.13 EPS25517.1 - 0.54 9.3 9.2 0.57 9.2 6.4 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DUF3381 PF11861.3 EPS25517.1 - 0.62 9.5 12.0 0.77 9.2 8.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) ATP-synt_E PF05680.7 EPS25517.1 - 0.69 9.9 4.7 0.94 9.4 3.3 1.2 1 0 0 1 1 1 0 ATP synthase E chain DUF4199 PF13858.1 EPS25517.1 - 0.79 9.6 3.1 0.93 9.3 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Spore_coat_CotO PF14153.1 EPS25517.1 - 0.92 8.9 10.3 1.2 8.5 7.1 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Pox_RNA_Pol_19 PF05320.7 EPS25517.1 - 0.96 9.1 9.4 1.2 8.8 6.5 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit YqfQ PF14181.1 EPS25517.1 - 0.99 9.4 7.7 1.3 9.0 5.3 1.1 1 0 0 1 1 1 0 YqfQ-like protein DUF2738 PF10927.3 EPS25517.1 - 1 8.3 5.0 1.2 8.0 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2738) Prothymosin PF03247.9 EPS25517.1 - 2.8 8.1 25.7 3.6 7.7 17.8 1.1 1 0 0 1 1 1 0 Prothymosin/parathymosin family Radial_spoke PF04712.7 EPS25517.1 - 3.6 6.2 17.1 4.3 5.9 11.8 1.0 1 0 0 1 1 1 0 Radial spokehead-like protein Prog_receptor PF02161.10 EPS25517.1 - 4.5 5.9 5.9 5.2 5.7 4.1 1.0 1 0 0 1 1 1 0 Progesterone receptor Paf1 PF03985.8 EPS25517.1 - 4.8 5.8 15.5 5.8 5.5 10.7 1.1 1 0 0 1 1 1 0 Paf1 Adeno_terminal PF02459.10 EPS25517.1 - 5.4 5.0 9.8 5.9 4.9 6.8 1.0 1 0 0 1 1 1 0 Adenoviral DNA terminal protein SspB PF04386.8 EPS25517.1 - 6.1 6.4 7.4 8.1 6.0 5.2 1.1 1 0 0 1 1 1 0 Stringent starvation protein B DUF1840 PF08895.6 EPS25517.1 - 6.2 6.8 8.0 10 6.1 5.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1840) DUF740 PF05340.7 EPS25517.1 - 6.4 5.0 6.8 6.3 5.0 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Spt5_N PF11942.3 EPS25517.1 - 6.9 7.3 20.7 11 6.7 14.3 1.3 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Rad54_N PF08658.5 EPS25517.1 - 7.5 6.2 7.2 11 5.6 5.0 1.3 1 0 0 1 1 1 0 Rad54 N terminal Fmp27 PF10344.4 EPS25517.1 - 9.3 3.7 6.8 11 3.5 4.7 1.0 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 Fungal_trans PF04082.13 EPS25518.1 - 1.1e-23 83.4 0.3 5.9e-22 77.7 0.0 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS25518.1 - 4.3e-07 29.7 8.2 7e-07 29.0 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cu-oxidase_3 PF07732.10 EPS25520.1 - 6.2e-35 119.4 0.2 2.7e-34 117.4 0.1 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EPS25520.1 - 2.2e-28 98.5 1.1 9.1e-22 77.0 0.1 2.7 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EPS25520.1 - 1.8e-16 60.4 0.0 7.8e-16 58.3 0.0 2.0 2 1 0 2 2 2 1 Multicopper oxidase Homeobox_KN PF05920.6 EPS25521.1 - 7.3e-15 54.3 1.4 2e-14 53.0 0.9 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EPS25521.1 - 1.7e-05 24.3 0.3 5.7e-05 22.6 0.2 1.9 1 0 0 1 1 1 1 Homeobox domain HTH_Tnp_Tc5 PF03221.11 EPS25521.1 - 0.031 14.1 0.0 0.08 12.7 0.0 1.7 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain HA PF03457.9 EPS25521.1 - 0.044 13.9 0.1 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 Helicase associated domain zf-C2H2_4 PF13894.1 EPS25521.1 - 0.19 12.1 24.4 0.052 13.9 0.7 5.1 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EPS25521.1 - 0.53 10.7 21.6 0.092 13.1 0.9 4.5 3 1 1 4 4 4 0 Zinc finger, C2H2 type tRNA-synt_1b PF00579.20 EPS25522.1 - 1.6e-53 181.7 0.0 2.1e-53 181.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) UQ_con PF00179.21 EPS25524.1 - 6.3e-11 41.8 0.0 9.8e-11 41.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EPS25524.1 - 0.038 13.8 0.1 0.069 13.0 0.0 1.5 1 0 0 1 1 1 0 RWD domain 2OG-FeII_Oxy_2 PF13532.1 EPS25526.1 - 9.3e-35 120.2 0.4 1.3e-34 119.7 0.2 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.7 EPS25526.1 - 5.8e-05 22.9 3.8 5.8e-05 22.9 2.7 1.9 2 0 0 2 2 2 1 GRF zinc finger CUE PF02845.11 EPS25526.1 - 0.024 14.0 0.1 0.045 13.2 0.0 1.4 1 0 0 1 1 1 0 CUE domain WD40 PF00400.27 EPS25527.1 - 8.3e-29 98.4 19.0 1.2e-08 34.5 0.1 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat DUF1014 PF06244.7 EPS25528.1 - 2.4e-23 82.6 11.6 8.7e-23 80.8 8.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) Peptidase_C13 PF01650.13 EPS25529.1 - 2.7e-41 141.5 0.1 3.9e-41 141.0 0.1 1.2 1 0 0 1 1 1 1 Peptidase C13 family CDRT4 PF15213.1 EPS25529.1 - 0.068 13.2 0.1 0.12 12.5 0.1 1.3 1 0 0 1 1 1 0 CMT1A duplicated region transcript 4 protein CDC45 PF02724.9 EPS25530.1 - 9.4e-243 806.8 0.0 1.8e-242 805.8 0.0 1.8 1 1 0 1 1 1 1 CDC45-like protein DUF1537 PF07005.6 EPS25531.1 - 1.3e-26 93.7 2.0 1.3e-26 93.7 1.4 1.5 2 0 0 2 2 2 1 Protein of unknown function, DUF1537 Glu_syn_central PF04898.9 EPS25531.1 - 0.064 12.5 0.0 0.22 10.7 0.0 1.8 2 0 0 2 2 2 0 Glutamate synthase central domain Cupin_8 PF13621.1 EPS25532.1 - 8.3e-32 110.6 0.0 2e-31 109.3 0.0 1.6 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EPS25532.1 - 3.2e-06 26.6 0.1 0.00032 20.0 0.0 2.2 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.17 EPS25532.1 - 0.0061 16.7 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 EPS25532.1 - 0.0096 15.4 0.0 0.035 13.5 0.0 1.9 1 0 0 1 1 1 1 Cupin domain GTP1_OBG PF01018.17 EPS25533.1 - 1.1e-38 132.4 6.5 6.2e-29 100.6 3.7 2.8 3 0 0 3 3 3 2 GTP1/OBG MMR_HSR1 PF01926.18 EPS25533.1 - 1.5e-20 73.2 0.0 2.6e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EPS25533.1 - 2.7e-08 33.2 0.0 5.9e-08 32.1 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B ArgK PF03308.11 EPS25533.1 - 0.0035 16.1 0.1 0.39 9.4 0.0 2.3 2 0 0 2 2 2 2 ArgK protein GTP_EFTU PF00009.22 EPS25533.1 - 0.0078 15.6 0.0 0.97 8.8 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EPS25533.1 - 0.0089 16.3 1.3 0.024 14.9 0.0 2.1 2 0 0 2 2 2 1 ABC transporter Miro PF08477.8 EPS25533.1 - 0.019 15.4 0.0 0.071 13.6 0.0 1.9 1 1 0 1 1 1 0 Miro-like protein Dynamin_N PF00350.18 EPS25533.1 - 0.036 13.8 0.0 1 9.1 0.0 2.2 1 1 0 2 2 2 0 Dynamin family MobB PF03205.9 EPS25533.1 - 0.12 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MFS_1 PF07690.11 EPS25536.1 - 5.9e-38 130.4 9.7 6.2e-29 100.8 0.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS25536.1 - 1.7e-10 40.0 4.9 3.2e-10 39.1 3.4 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 EPS25536.1 - 0.00026 19.4 5.0 0.00026 19.4 3.4 2.9 2 1 0 2 2 2 1 MFS/sugar transport protein MFS_3 PF05977.8 EPS25536.1 - 1.4 6.9 11.3 0.57 8.2 3.0 2.3 2 1 0 2 2 2 0 Transmembrane secretion effector Fungal_trans PF04082.13 EPS25537.1 - 2.9e-30 105.0 0.0 5.8e-30 104.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS25537.1 - 8.6e-09 35.1 11.3 1.3e-08 34.5 7.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DnaJ PF00226.26 EPS25538.1 - 9.6e-20 70.0 1.6 9.6e-20 70.0 1.1 1.8 2 0 0 2 2 2 1 DnaJ domain Adenylsucc_synt PF00709.16 EPS25539.1 - 3.1e-154 513.6 0.0 3.5e-154 513.5 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase DEAD PF00270.24 EPS25540.1 - 2.3e-42 144.3 0.1 3.8e-42 143.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPS25540.1 - 7.4e-20 70.5 0.5 1.6e-19 69.4 0.3 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPS25540.1 - 0.00024 20.9 0.0 0.0005 19.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 EPS25540.1 - 0.11 11.7 0.3 0.33 10.1 0.1 1.8 2 0 0 2 2 2 0 SecA DEAD-like domain Pyr_redox_2 PF07992.9 EPS25541.1 - 7.4e-17 61.8 0.5 5.7e-09 36.1 0.0 3.7 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPS25541.1 - 3.3e-15 56.2 0.7 1.9e-10 41.0 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPS25541.1 - 8.2e-09 35.4 3.8 0.00048 19.9 0.0 4.2 2 2 1 4 4 4 1 FAD-NAD(P)-binding DAO PF01266.19 EPS25541.1 - 4.3e-08 32.4 5.1 0.00017 20.6 0.0 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EPS25541.1 - 6e-07 29.7 2.9 0.096 12.7 0.6 3.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EPS25541.1 - 2.5e-06 26.6 2.8 0.00041 19.3 0.0 3.4 4 0 0 4 4 4 1 Lycopene cyclase protein Thi4 PF01946.12 EPS25541.1 - 3.7e-05 22.9 2.3 0.0021 17.1 0.1 2.6 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.1 EPS25541.1 - 7.9e-05 21.7 0.5 0.14 11.0 0.1 2.5 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 EPS25541.1 - 0.00045 18.9 6.0 0.7 8.4 0.1 3.1 2 1 0 3 3 3 2 Tryptophan halogenase NAD_binding_7 PF13241.1 EPS25541.1 - 0.00081 19.6 0.1 1 9.6 0.0 2.5 2 0 0 2 2 2 2 Putative NAD(P)-binding NAD_binding_8 PF13450.1 EPS25541.1 - 0.0013 18.7 0.3 0.0052 16.7 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.13 EPS25541.1 - 0.0014 18.5 0.1 0.81 9.6 0.0 2.8 2 0 0 2 2 2 1 TrkA-N domain KR PF08659.5 EPS25541.1 - 0.0068 16.0 0.1 0.063 12.9 0.1 2.3 2 0 0 2 2 2 1 KR domain ApbA PF02558.11 EPS25541.1 - 0.019 14.3 0.5 1.2 8.5 0.0 2.7 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 EPS25541.1 - 0.032 13.2 2.3 0.12 11.4 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 EPS25541.1 - 0.053 11.9 2.6 0.66 8.3 0.0 2.9 3 1 1 4 4 4 0 HI0933-like protein GIDA PF01134.17 EPS25541.1 - 0.092 11.5 8.4 4.8 5.9 0.0 4.0 2 1 1 4 4 4 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 EPS25541.1 - 0.11 12.1 0.5 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 EPS25541.1 - 0.12 11.2 0.0 0.12 11.2 0.0 2.0 3 1 0 3 3 3 0 FAD binding domain ThiF PF00899.16 EPS25541.1 - 0.12 12.1 3.6 4.3 7.1 0.2 2.4 2 0 0 2 2 2 0 ThiF family adh_short PF00106.20 EPS25541.1 - 0.19 11.6 0.1 0.19 11.6 0.1 2.2 3 0 0 3 3 2 0 short chain dehydrogenase ADH_zinc_N PF00107.21 EPS25542.1 - 6.9e-25 87.0 0.0 1.2e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPS25542.1 - 1e-06 29.6 0.0 2.1e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EPS25542.1 - 0.051 13.5 0.0 0.11 12.5 0.0 1.5 1 1 0 1 1 1 0 NADH(P)-binding CybS PF05328.7 EPS25543.1 - 5.6e-51 171.6 0.0 7.1e-51 171.3 0.0 1.1 1 0 0 1 1 1 1 CybS Maf PF02545.9 EPS25544.1 - 2.1e-46 157.5 0.0 2.7e-46 157.1 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein HLH PF00010.21 EPS25545.1 - 1.8e-08 33.9 0.0 2.7e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Umbravirus_LDM PF04817.7 EPS25545.1 - 0.002 17.3 0.1 0.0022 17.1 0.1 1.0 1 0 0 1 1 1 1 Umbravirus long distance movement (LDM) family GFA PF04828.9 EPS25546.1 - 0.0021 17.9 0.0 0.0045 16.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme QRPTase_N PF02749.11 EPS25546.1 - 0.14 11.9 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain DUF2890 PF11081.3 EPS25546.1 - 0.38 10.7 3.8 0.64 10.0 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Abhydrolase_6 PF12697.2 EPS25548.1 - 3.3e-20 72.9 3.3 4.3e-20 72.5 2.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPS25548.1 - 1.5e-10 41.0 0.0 1.8e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPS25548.1 - 7.1e-10 38.8 0.1 1.5e-09 37.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EPS25548.1 - 0.0017 17.8 0.1 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Ndr PF03096.9 EPS25548.1 - 0.023 13.1 0.1 0.036 12.5 0.0 1.2 1 0 0 1 1 1 0 Ndr family Hydrolase_4 PF12146.3 EPS25548.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Fungal_trans PF04082.13 EPS25549.1 - 6.6e-21 74.3 0.2 9.9e-21 73.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS25549.1 - 2.8e-05 23.9 12.3 5.2e-05 23.0 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EPS25550.1 - 3.5e-44 150.9 38.9 6.7e-44 150.0 22.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS25550.1 - 3.2e-13 49.0 8.8 3.2e-13 49.0 6.1 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter NADHdh_A3 PF14987.1 EPS25550.1 - 4.2 7.3 6.0 1.3 9.0 0.2 2.6 2 0 0 2 2 2 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 LGT PF01790.13 EPS25551.1 - 0.31 9.9 8.1 0.083 11.8 0.5 2.3 2 0 0 2 2 2 0 Prolipoprotein diacylglyceryl transferase Fungal_trans_2 PF11951.3 EPS25552.1 - 3.6e-13 48.8 5.9 2.6e-12 46.0 4.1 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS25552.1 - 1.8e-07 30.9 11.0 1.8e-07 30.9 7.6 2.6 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VWA PF00092.23 EPS25553.1 - 0.00011 22.0 0.0 0.1 12.3 0.0 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain VWA_2 PF13519.1 EPS25553.1 - 0.00014 22.0 0.0 0.00063 19.9 0.0 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 EPS25553.1 - 0.0046 16.8 0.0 0.0076 16.0 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus Apc4 PF12896.2 EPS25555.1 - 3e-66 222.7 1.3 4.3e-66 222.2 0.9 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Apc4_WD40 PF12894.2 EPS25555.1 - 5.9e-18 64.0 0.0 1.7e-17 62.6 0.0 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.27 EPS25555.1 - 0.0009 19.0 0.0 0.014 15.2 0.0 2.9 3 0 0 3 3 3 1 WD domain, G-beta repeat HEAT PF02985.17 EPS25556.1 - 9.1e-13 47.1 7.0 0.00056 19.7 0.1 8.3 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 EPS25556.1 - 1.7e-12 47.4 1.4 2e-08 34.4 0.1 7.9 8 3 3 11 11 11 2 HEAT-like repeat HEAT_2 PF13646.1 EPS25556.1 - 2.3e-12 47.0 9.6 0.0002 21.5 0.0 6.4 4 2 2 6 6 6 3 HEAT repeats IBN_N PF03810.14 EPS25556.1 - 8e-10 38.5 4.3 3.3e-09 36.5 0.3 3.7 4 0 0 4 4 4 1 Importin-beta N-terminal domain CLASP_N PF12348.3 EPS25556.1 - 6.3e-07 28.9 0.1 0.11 11.7 0.0 4.3 3 2 1 5 5 5 2 CLASP N terminal DUF3385 PF11865.3 EPS25556.1 - 0.022 14.7 0.6 3.2 7.6 0.4 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF3385) HEAT_PBS PF03130.11 EPS25556.1 - 0.026 14.9 1.2 94 3.9 0.0 5.3 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Dopey_N PF04118.9 EPS25556.1 - 0.068 11.9 0.3 5.3 5.7 0.0 3.0 3 1 0 3 3 3 0 Dopey, N-terminal PNPase PF03726.9 EPS25556.1 - 0.1 12.8 0.9 1 9.6 0.0 2.9 3 0 0 3 3 3 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain Arm PF00514.18 EPS25556.1 - 0.31 10.9 3.3 8.2 6.4 0.1 3.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Ribosomal_S8 PF00410.14 EPS25557.1 - 1.7e-23 82.8 0.0 2.3e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 His_Phos_1 PF00300.17 EPS25558.1 - 1.7e-18 67.2 0.0 2.3e-18 66.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PINIT PF14324.1 EPS25558.1 - 0.058 13.4 0.5 0.098 12.7 0.4 1.3 1 0 0 1 1 1 0 PINIT domain ubiquitin PF00240.18 EPS25559.1 - 7e-05 22.1 0.0 7e-05 22.1 0.0 2.3 3 0 0 3 3 3 1 Ubiquitin family DUF2407 PF10302.4 EPS25559.1 - 0.00031 20.8 2.1 0.00045 20.3 0.0 2.2 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain PS_Dcarbxylase PF02666.10 EPS25560.1 - 2e-83 278.6 0.0 1.3e-82 276.0 0.0 1.9 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase FAD_binding_3 PF01494.14 EPS25561.1 - 6.9e-10 38.5 0.2 2.3e-09 36.7 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EPS25561.1 - 5.4e-06 25.5 0.1 3e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EPS25561.1 - 9.8e-06 25.8 0.0 0.00018 21.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPS25561.1 - 0.00017 21.5 0.0 0.00044 20.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EPS25561.1 - 0.015 15.1 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPS25561.1 - 0.027 13.5 0.0 0.046 12.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_7 PF13241.1 EPS25561.1 - 0.054 13.7 0.0 0.1 12.8 0.0 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.11 EPS25561.1 - 0.074 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 EPS25561.1 - 0.086 11.6 0.5 0.37 9.6 0.2 1.9 1 1 1 2 2 2 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 EPS25561.1 - 0.097 11.7 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Fungal_trans PF04082.13 EPS25562.1 - 4e-13 48.8 0.0 6.7e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS25562.1 - 5.4e-09 35.8 9.4 9.9e-09 34.9 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mem_trans PF03547.13 EPS25563.1 - 1e-53 182.0 0.0 1.9e-53 181.1 0.0 1.4 1 1 0 1 1 1 1 Membrane transport protein Cu-oxidase_3 PF07732.10 EPS25564.1 - 4.9e-37 126.2 0.2 1.3e-34 118.4 0.0 3.2 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EPS25564.1 - 4.3e-32 110.4 2.1 2.2e-30 104.9 0.1 3.6 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 EPS25564.1 - 2.5e-16 60.0 0.0 2.5e-15 56.7 0.0 2.2 2 0 0 2 2 2 1 Multicopper oxidase Phosphoesterase PF04185.9 EPS25566.1 - 9.7e-73 245.5 2.8 1.3e-72 245.0 2.0 1.1 1 0 0 1 1 1 1 Phosphoesterase family ApbA_C PF08546.6 EPS25567.1 - 1.7e-34 118.4 0.0 2.4e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EPS25567.1 - 1e-27 96.4 0.0 1.9e-27 95.5 0.0 1.4 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Ribonuc_L-PSP PF01042.16 EPS25568.1 - 2.8e-37 127.1 0.0 3.2e-37 126.9 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP GPI-anchored PF10342.4 EPS25569.1 - 0.0018 18.7 0.2 0.0029 18.0 0.1 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Choline_kinase PF01633.15 EPS25571.1 - 1.3e-58 198.1 0.0 1.9e-58 197.5 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 EPS25571.1 - 1.6e-14 53.0 0.0 4.2e-14 51.7 0.0 1.7 2 0 0 2 2 2 1 Choline kinase N terminus APH PF01636.18 EPS25571.1 - 3.3e-09 36.8 0.6 2.8e-08 33.8 0.1 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Peptidase_C12 PF01088.16 EPS25572.1 - 5.3e-73 244.7 0.0 7e-73 244.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Cellulase PF00150.13 EPS25573.1 - 3.2e-56 190.5 0.7 4.3e-56 190.1 0.5 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 EPS25573.1 - 3.3e-13 49.0 16.9 1.3e-12 47.1 11.7 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.7 EPS25573.1 - 0.02 14.9 1.3 0.061 13.3 0.9 1.8 1 0 0 1 1 1 0 Toxin 7 PAN_3 PF08277.7 EPS25574.1 - 2.7e-08 33.3 27.5 0.0033 16.9 3.5 4.5 4 0 0 4 4 4 3 PAN-like domain PAN_4 PF14295.1 EPS25574.1 - 0.00076 19.1 53.4 0.0048 16.5 4.3 6.0 6 0 0 6 6 6 4 PAN domain PLAT PF01477.18 EPS25574.1 - 0.037 14.4 0.1 3 8.2 0.0 2.5 2 0 0 2 2 2 0 PLAT/LH2 domain Mito_fiss_reg PF05308.6 EPS25574.1 - 0.24 10.7 1.8 0.49 9.7 1.3 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator VWA_2 PF13519.1 EPS25575.1 - 2.7e-06 27.6 0.3 4.9e-06 26.7 0.1 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 EPS25575.1 - 0.012 15.4 0.1 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 vWA found in TerF C terminus Zn_clus PF00172.13 EPS25576.1 - 5.5e-07 29.3 14.6 1.1e-06 28.3 10.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EPS25576.1 - 3e-06 26.0 2.3 5.3e-06 25.2 1.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain CVNH PF08881.5 EPS25579.1 - 2.2e-07 31.0 0.0 3.9e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 CVNH domain CVNH PF08881.5 EPS25580.1 - 3.2e-10 40.1 0.0 4e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 CVNH domain HEAT_EZ PF13513.1 EPS25581.1 - 6.2e-31 106.0 10.5 5.2e-13 49.0 0.0 11.4 9 2 3 12 12 12 3 HEAT-like repeat HEAT_2 PF13646.1 EPS25581.1 - 1.3e-24 86.3 0.2 1.7e-08 34.6 0.0 8.5 4 3 5 9 9 9 6 HEAT repeats HEAT PF02985.17 EPS25581.1 - 5.3e-22 75.8 12.6 9.4e-05 22.1 0.0 10.1 11 0 0 11 11 11 5 HEAT repeat CLASP_N PF12348.3 EPS25581.1 - 7.1e-10 38.6 0.0 1.2 8.4 0.0 7.2 3 1 5 8 8 8 3 CLASP N terminal Vac14_Fab1_bd PF12755.2 EPS25581.1 - 1.1e-08 35.3 0.1 0.21 11.9 0.0 6.1 4 2 2 6 6 6 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EPS25581.1 - 1.2e-08 33.7 2.9 0.00058 18.3 0.1 4.9 3 2 1 4 4 4 3 Adaptin N terminal region Cnd1 PF12717.2 EPS25581.1 - 9.1e-06 25.6 7.1 0.038 13.8 0.2 6.8 6 2 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.7 EPS25581.1 - 1.1e-05 25.2 0.0 0.27 10.9 0.0 4.4 3 2 1 5 5 5 2 rRNA processing/ribosome biogenesis MMS19_C PF12460.3 EPS25581.1 - 0.00011 21.0 2.4 0.021 13.5 0.0 4.5 6 0 0 6 6 6 1 RNAPII transcription regulator C-terminal Arm PF00514.18 EPS25581.1 - 0.0021 17.8 7.1 0.62 9.9 0.0 6.4 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat UME PF08064.8 EPS25581.1 - 0.03 14.2 0.1 0.37 10.7 0.0 3.0 3 0 0 3 3 3 0 UME (NUC010) domain HEAT_PBS PF03130.11 EPS25581.1 - 0.13 12.7 5.0 15 6.3 0.0 5.1 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat Syja_N PF02383.13 EPS25582.1 - 8.1e-98 327.1 0.0 1.2e-97 326.4 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 EPS25582.1 - 8.6e-37 125.0 0.0 1.6e-36 124.1 0.0 1.5 1 0 0 1 1 1 1 Inositol phosphatase Mg_trans_NIPA PF05653.9 EPS25583.1 - 1.3e-102 342.7 11.6 1.6e-102 342.5 8.0 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EPS25583.1 - 2.3e-07 30.9 2.5 2.3e-07 30.9 1.7 3.3 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EPS25583.1 - 3.2e-05 23.9 6.9 3.2e-05 23.9 4.8 3.3 3 1 1 4 4 4 1 EamA-like transporter family TrbC PF04956.8 EPS25583.1 - 0.1 12.6 4.5 0.34 10.9 3.1 1.9 1 0 0 1 1 1 0 TrbC/VIRB2 family DUF2937 PF11157.3 EPS25583.1 - 0.86 8.9 3.1 0.5 9.6 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) DUF2420 PF10336.4 EPS25585.1 - 1.5e-09 37.3 0.2 1.5e-09 37.3 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2420) Adap_comp_sub PF00928.16 EPS25586.1 - 6e-16 58.3 0.0 9.3e-16 57.7 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EPS25586.1 - 3.1e-07 30.1 0.2 5.1e-07 29.4 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 EPS25586.1 - 4.2e-06 26.1 0.1 6.6e-05 22.2 0.0 2.1 1 1 0 1 1 1 1 Muniscin C-terminal mu homology domain RPM2 PF08579.6 EPS25586.1 - 0.002 18.2 0.4 0.0041 17.2 0.3 1.5 1 0 0 1 1 1 1 Mitochondrial ribonuclease P subunit (RPM2) BACON PF13004.2 EPS25586.1 - 0.11 12.7 2.3 1.6 9.0 0.3 2.6 2 0 0 2 2 2 0 Bacteroidetes-Associated Carbohydrate-binding Often N-terminal EspF PF04806.7 EPS25586.1 - 0.96 9.6 4.2 3.4 7.9 2.6 2.1 2 0 0 2 2 2 0 EspF protein repeat Fungal_trans PF04082.13 EPS25587.1 - 5.7e-20 71.2 0.0 1.4e-19 69.9 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS25587.1 - 3.6e-05 23.5 16.2 7.9e-05 22.4 11.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OMPdecase PF00215.19 EPS25589.1 - 1.8e-06 27.5 0.0 5.4e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Ish1 PF10281.4 EPS25589.1 - 0.07 13.2 0.4 1.8 8.7 0.4 2.6 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein Cyt-b5 PF00173.23 EPS25591.1 - 2.5e-22 78.4 0.6 1.3e-21 76.1 0.1 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 EPS25591.1 - 1.1e-08 35.5 19.4 9e-08 32.5 13.3 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily RRM_1 PF00076.17 EPS25592.1 - 8.7e-45 150.2 0.4 1.6e-21 75.6 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS25592.1 - 1.3e-35 121.1 0.1 6.8e-19 67.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 EPS25592.1 - 4.4e-30 103.7 0.2 1.2e-29 102.4 0.1 1.7 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.1 EPS25592.1 - 4.9e-22 77.5 0.0 1.4e-09 37.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EPS25592.1 - 0.0046 16.6 0.3 0.36 10.6 0.0 3.1 3 0 0 3 3 3 1 Limkain b1 RRM_3 PF08777.6 EPS25592.1 - 0.0049 16.6 0.0 0.024 14.5 0.0 2.1 2 0 0 2 2 2 1 RNA binding motif PP2C PF00481.16 EPS25593.1 - 7.1e-35 120.6 0.0 2.3e-28 99.3 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EPS25593.1 - 0.0021 17.4 0.0 0.004 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C CDP-OH_P_transf PF01066.16 EPS25595.1 - 1.2e-17 64.0 7.7 2.2e-17 63.1 5.2 1.7 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Reo_sigmaC PF04582.7 EPS25596.1 - 0.066 12.3 0.9 0.074 12.2 0.6 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Zn_clus PF00172.13 EPS25597.1 - 2.4e-08 33.7 13.9 4.7e-08 32.8 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sec63 PF02889.11 EPS25598.1 - 9.7e-52 176.1 0.0 4.1e-50 170.7 0.0 2.1 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 EPS25598.1 - 3e-18 65.2 0.3 7.1e-18 64.1 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain 7tm_1 PF00001.16 EPS25598.1 - 0.032 13.3 0.0 0.065 12.3 0.0 1.4 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF2937 PF11157.3 EPS25598.1 - 0.11 11.8 0.0 6.2 6.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) DUF3040 PF11239.3 EPS25598.1 - 1.5 8.9 7.5 38 4.4 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3040) Peptidase_M24 PF00557.19 EPS25600.1 - 2.2e-57 194.0 0.0 3e-57 193.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EPS25600.1 - 1.6e-23 82.6 0.0 3.1e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain SPRY PF00622.23 EPS25601.1 - 1e-19 70.8 0.1 2.4e-19 69.6 0.0 1.7 2 0 0 2 2 2 1 SPRY domain PDEase_II PF02112.10 EPS25602.1 - 5.8e-49 166.8 0.0 1.9e-24 86.2 0.0 3.2 3 1 0 3 3 3 3 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 EPS25602.1 - 8.5e-05 22.1 0.0 0.00022 20.8 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EPS25602.1 - 0.00032 20.4 1.4 0.0013 18.4 1.0 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Acyl-CoA_dh_1 PF00441.19 EPS25603.1 - 2e-40 138.3 8.7 3.4e-40 137.5 6.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EPS25603.1 - 1.9e-25 89.6 4.1 3e-25 88.9 0.1 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EPS25603.1 - 1.2e-18 66.3 0.0 2.9e-18 65.0 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EPS25603.1 - 1.1e-15 58.1 4.0 1.8e-15 57.3 2.8 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EPS25603.1 - 0.03 13.6 0.1 0.13 11.6 0.1 1.9 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal bZIP_1 PF00170.16 EPS25604.1 - 2e-07 30.8 8.1 2.5e-06 27.3 4.2 2.2 1 1 1 2 2 2 2 bZIP transcription factor Mito_fiss_reg PF05308.6 EPS25604.1 - 1.1e-06 28.2 10.0 1.1e-06 28.2 6.9 2.5 2 1 0 2 2 2 1 Mitochondrial fission regulator NPV_P10 PF05531.7 EPS25604.1 - 0.0011 19.1 1.1 0.0022 18.2 0.7 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein DUF972 PF06156.8 EPS25604.1 - 0.0014 18.9 0.4 0.0031 17.8 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF972) FlxA PF14282.1 EPS25604.1 - 0.0022 17.9 5.4 0.0022 17.9 3.8 2.0 2 0 0 2 2 2 1 FlxA-like protein bZIP_2 PF07716.10 EPS25604.1 - 0.0024 17.6 14.5 0.02 14.7 6.1 2.3 1 1 1 2 2 2 2 Basic region leucine zipper ATG16 PF08614.6 EPS25604.1 - 0.006 16.4 5.4 0.012 15.4 3.7 1.5 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) Med9 PF07544.8 EPS25604.1 - 0.0076 15.9 4.7 0.016 14.9 3.3 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 HALZ PF02183.13 EPS25604.1 - 0.011 15.4 0.7 0.11 12.2 0.4 2.2 1 1 0 1 1 1 0 Homeobox associated leucine zipper Phage_GP20 PF06810.6 EPS25604.1 - 0.012 15.1 4.0 0.017 14.5 2.7 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 GAS PF13851.1 EPS25604.1 - 0.013 14.6 5.4 0.019 14.1 3.7 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Tropomyosin_1 PF12718.2 EPS25604.1 - 0.046 13.5 7.2 0.1 12.4 4.7 1.7 1 1 1 2 2 2 0 Tropomyosin like Calici_MSP PF05752.6 EPS25604.1 - 0.051 13.1 2.0 0.055 13.0 0.5 1.8 2 0 0 2 2 2 0 Calicivirus minor structural protein FlaC_arch PF05377.6 EPS25604.1 - 0.072 12.9 0.6 0.15 11.9 0.3 1.6 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) DivIC PF04977.10 EPS25604.1 - 0.12 11.9 8.4 0.071 12.6 0.9 2.3 1 1 1 2 2 2 0 Septum formation initiator DUF1192 PF06698.6 EPS25604.1 - 0.15 11.8 3.7 0.58 10.0 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) DUF724 PF05266.9 EPS25604.1 - 0.24 10.9 4.2 0.36 10.4 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF3450 PF11932.3 EPS25604.1 - 0.35 10.1 8.0 0.51 9.5 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CortBP2 PF09727.4 EPS25604.1 - 0.51 9.8 8.3 0.72 9.3 5.8 1.1 1 0 0 1 1 1 0 Cortactin-binding protein-2 Kinetocho_Slk19 PF12709.2 EPS25604.1 - 0.62 10.1 3.9 4.6 7.3 2.7 2.1 1 1 0 1 1 1 0 Central kinetochore-associated DUF484 PF04340.7 EPS25604.1 - 0.82 9.0 5.8 0.71 9.2 3.1 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF484 DivIVA PF05103.8 EPS25604.1 - 1.1 9.3 8.3 2.5 8.1 0.1 2.2 1 1 1 2 2 2 0 DivIVA protein GWT1 PF06423.7 EPS25605.1 - 2e-42 144.5 3.6 9.9e-42 142.2 2.2 2.2 2 1 0 2 2 2 1 GWT1 Amidase PF01425.16 EPS25606.1 - 4.5e-90 302.6 0.0 5.9e-90 302.2 0.0 1.1 1 0 0 1 1 1 1 Amidase APC10 PF03256.11 EPS25607.1 - 5.6e-44 150.0 0.0 1.5e-43 148.7 0.0 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) CDC45 PF02724.9 EPS25607.1 - 0.0001 20.5 1.7 0.00011 20.3 1.1 1.2 1 0 0 1 1 1 1 CDC45-like protein Spore_coat_CotO PF14153.1 EPS25607.1 - 0.0076 15.7 3.9 0.011 15.2 2.7 1.2 1 0 0 1 1 1 1 Spore coat protein CotO SAPS PF04499.10 EPS25607.1 - 0.019 13.6 0.1 0.026 13.1 0.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ycf1 PF05758.7 EPS25607.1 - 0.6 7.7 2.2 0.7 7.5 1.5 1.1 1 0 0 1 1 1 0 Ycf1 Zip PF02535.17 EPS25607.1 - 5.5 5.8 7.1 7.7 5.4 4.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Radial_spoke PF04712.7 EPS25607.1 - 5.5 5.6 15.8 10 4.7 10.9 1.4 1 0 0 1 1 1 0 Radial spokehead-like protein DUF1510 PF07423.6 EPS25607.1 - 9.2 5.5 16.9 15 4.8 11.1 1.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) Iso_dh PF00180.15 EPS25608.1 - 5.4e-132 439.9 0.0 6.2e-132 439.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ALO PF04030.9 EPS25609.1 - 1.5e-87 293.4 0.3 2.2e-87 292.9 0.2 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 EPS25609.1 - 5.1e-34 116.7 0.1 7.7e-34 116.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain DUF4045 PF13254.1 EPS25610.1 - 1e-128 430.2 34.4 1e-128 430.2 23.8 4.9 4 2 0 4 4 4 1 Domain of unknown function (DUF4045) Gelsolin PF00626.17 EPS25610.1 - 5.1e-11 42.0 0.0 0.014 15.0 0.0 3.6 3 0 0 3 3 3 3 Gelsolin repeat Arf PF00025.16 EPS25611.1 - 1.4e-64 216.5 1.7 1.6e-64 216.3 1.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EPS25611.1 - 2.8e-13 49.5 0.0 3.3e-13 49.3 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EPS25611.1 - 1.2e-11 43.9 4.1 1e-06 27.7 0.2 2.6 2 1 1 3 3 3 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EPS25611.1 - 4.8e-11 42.2 0.0 5.9e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EPS25611.1 - 3.4e-09 36.6 0.0 4.7e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EPS25611.1 - 3.8e-08 32.7 0.0 4.5e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EPS25611.1 - 2.2e-07 30.5 0.0 2.5e-05 23.8 0.0 2.1 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EPS25611.1 - 2.2e-07 31.4 0.0 3e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein HCV_NS1 PF01560.12 EPS25611.1 - 0.0014 17.1 0.0 0.0016 16.9 0.0 1.1 1 0 0 1 1 1 1 Hepatitis C virus non-structural protein E2/NS1 FeoB_N PF02421.13 EPS25611.1 - 0.0083 15.4 0.4 0.024 13.8 0.3 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_17 PF13207.1 EPS25611.1 - 0.025 15.4 0.1 0.044 14.5 0.1 1.4 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EPS25611.1 - 0.057 12.9 0.1 0.11 11.9 0.1 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation 6PF2K PF01591.13 EPS25611.1 - 0.06 12.4 0.2 0.15 11.1 0.1 1.6 1 1 1 2 2 2 0 6-phosphofructo-2-kinase NACHT PF05729.7 EPS25611.1 - 0.072 12.7 0.3 2.2 7.8 0.0 2.1 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.10 EPS25611.1 - 0.093 12.4 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 NTPase Amdo_NSP PF12475.3 EPS25611.1 - 0.11 12.4 0.0 0.4 10.6 0.0 1.9 2 0 0 2 2 2 0 Amdovirus non-structural protein DEAD PF00270.24 EPS25612.1 - 6.4e-45 152.6 0.5 5e-44 149.7 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPS25612.1 - 2.6e-26 91.2 0.0 1.1e-25 89.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EPS25612.1 - 1.6e-05 23.4 0.0 1.6e-05 23.4 0.0 2.8 2 1 0 3 3 3 1 Protein of unknown function (DUF1253) Fungal_trans PF04082.13 EPS25614.1 - 3.4e-25 88.3 0.1 3.4e-25 88.3 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS25614.1 - 6.8e-11 41.8 6.9 1.2e-10 41.1 4.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zip PF02535.17 EPS25614.1 - 0.011 14.7 11.0 0.023 13.7 7.6 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.11 EPS25614.1 - 5.9 6.7 7.8 12 5.7 5.4 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PAT1 PF09770.4 EPS25614.1 - 9.9 4.2 23.8 15 3.6 16.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ferric_reduct PF01794.14 EPS25615.1 - 1.2e-18 67.3 12.8 3.4e-18 65.9 8.8 1.8 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EPS25615.1 - 4.6e-17 62.3 0.0 6.5e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EPS25615.1 - 1e-10 41.3 0.0 2e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain FAD_binding_6 PF00970.19 EPS25615.1 - 0.013 15.6 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EPS25615.1 - 0.13 12.8 0.0 29 5.2 0.0 2.4 1 1 0 2 2 2 0 Oxidoreductase NAD-binding domain Sugar_tr PF00083.19 EPS25616.1 - 1.3e-81 274.5 21.9 1.5e-81 274.3 15.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS25616.1 - 6.6e-16 57.9 26.9 6.6e-16 57.9 18.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Amidohydro_2 PF04909.9 EPS25617.1 - 7.1e-26 91.3 0.2 8.4e-26 91.1 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase CD20 PF04103.10 EPS25618.1 - 0.054 13.4 0.4 0.066 13.1 0.3 1.1 1 0 0 1 1 1 0 CD20-like family SVWC PF15430.1 EPS25618.1 - 0.14 12.6 0.6 0.14 12.6 0.4 2.4 1 1 1 2 2 2 0 Single domain von Willebrand factor type C Pyr_redox_2 PF07992.9 EPS25620.1 - 3.4e-38 131.5 0.0 6.6e-38 130.6 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EPS25620.1 - 1.6e-34 118.1 0.3 5.3e-34 116.5 0.2 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EPS25620.1 - 3.3e-14 53.0 0.2 1e-13 51.4 0.2 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPS25620.1 - 6.6e-05 23.0 0.1 0.00022 21.3 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EPS25620.1 - 0.00074 18.5 0.0 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) 3HCDH_N PF02737.13 EPS25620.1 - 0.053 13.1 0.3 0.053 13.1 0.2 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 EPS25620.1 - 0.066 12.0 3.8 7.8 5.2 0.0 3.1 3 0 0 3 3 3 0 FAD binding domain Methyltransf_23 PF13489.1 EPS25621.1 - 6.2e-14 52.0 0.0 1e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS25621.1 - 6.9e-10 39.5 0.0 1.9e-08 34.8 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPS25621.1 - 3.2e-05 24.3 0.0 0.00027 21.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPS25621.1 - 0.00015 22.2 0.0 0.00043 20.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPS25621.1 - 0.00081 19.7 0.0 0.019 15.3 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EPS25621.1 - 0.00091 18.3 0.0 0.0022 17.0 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 EPS25621.1 - 0.0013 18.3 0.0 0.014 15.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPS25621.1 - 0.0079 16.2 0.0 0.019 15.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPS25621.1 - 0.034 13.2 0.0 2.7 7.0 0.0 2.7 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family PrmA PF06325.8 EPS25621.1 - 0.046 12.8 0.0 0.093 11.8 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CheR PF01739.13 EPS25621.1 - 0.086 12.1 0.0 0.16 11.2 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain MTS PF05175.9 EPS25621.1 - 0.13 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain p450 PF00067.17 EPS25624.1 - 2.7e-56 191.0 0.0 3.8e-56 190.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 EPS25625.1 - 1.7e-48 165.0 0.0 8.9e-46 156.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPS25625.1 - 4.1e-29 101.4 0.0 1.9e-28 99.2 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPS25625.1 - 5.1e-05 22.3 0.0 7.7e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EPS25625.1 - 0.00096 18.0 0.1 0.0016 17.3 0.1 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 EPS25625.1 - 0.022 14.4 0.2 0.15 11.7 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EPS25625.1 - 0.025 13.4 0.1 0.037 12.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Dabb PF07876.7 EPS25627.1 - 2.5e-12 47.0 0.1 3.5e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain Fungal_trans PF04082.13 EPS25628.1 - 4.2e-21 74.9 1.0 6.4e-21 74.4 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS25628.1 - 2.8e-08 33.5 11.3 5.6e-08 32.5 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ldh_2 PF02615.9 EPS25629.1 - 9.5e-95 317.1 0.0 1.1e-94 316.9 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Pkinase PF00069.20 EPS25630.1 - 3e-64 216.6 0.0 4.6e-64 216.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS25630.1 - 6.6e-36 123.7 0.0 7.5e-31 107.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EPS25630.1 - 4.5e-05 22.5 0.0 0.031 13.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like RIO1 PF01163.17 EPS25630.1 - 0.0006 19.2 0.0 0.0012 18.1 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EPS25630.1 - 0.004 16.9 0.1 0.013 15.2 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EPS25630.1 - 0.046 12.7 0.0 0.081 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EPS25630.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Senescence PF06911.7 EPS25632.1 - 1.7e-46 158.1 3.2 2.4e-46 157.6 2.2 1.2 1 0 0 1 1 1 1 Senescence-associated protein Cupin_2 PF07883.6 EPS25632.1 - 0.095 12.2 0.1 0.26 10.7 0.1 1.7 1 0 0 1 1 1 0 Cupin domain Dus PF01207.12 EPS25633.1 - 4e-39 134.2 0.0 8e-28 97.1 0.0 2.8 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 EPS25633.1 - 0.074 12.7 0.3 0.074 12.7 0.2 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Bap31 PF05529.7 EPS25634.1 - 1.4e-65 220.4 2.0 1.6e-65 220.1 1.4 1.1 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like DivIC PF04977.10 EPS25634.1 - 0.00016 21.0 3.0 0.013 14.9 0.1 3.3 3 1 0 3 3 3 1 Septum formation initiator HALZ PF02183.13 EPS25634.1 - 0.00027 20.5 0.6 0.00069 19.2 0.4 1.7 1 1 0 1 1 1 1 Homeobox associated leucine zipper Spc7 PF08317.6 EPS25634.1 - 0.0035 16.0 1.2 0.0047 15.6 0.8 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Phage_GP20 PF06810.6 EPS25634.1 - 0.0062 15.9 2.4 0.0086 15.5 1.6 1.2 1 0 0 1 1 1 1 Phage minor structural protein GP20 Mod_r PF07200.8 EPS25634.1 - 0.0076 16.1 0.6 0.011 15.6 0.4 1.4 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein SlyX PF04102.7 EPS25634.1 - 0.014 15.7 1.2 0.03 14.6 0.1 2.0 3 0 0 3 3 3 0 SlyX IncA PF04156.9 EPS25634.1 - 0.016 14.8 0.3 0.03 13.9 0.2 1.5 1 0 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 EPS25634.1 - 0.016 14.9 3.3 0.033 13.9 2.3 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding FlxA PF14282.1 EPS25634.1 - 0.017 15.0 2.1 0.034 14.0 1.5 1.6 1 0 0 1 1 1 0 FlxA-like protein DUF4200 PF13863.1 EPS25634.1 - 0.044 13.7 0.9 0.074 13.0 0.4 1.5 2 0 0 2 2 1 0 Domain of unknown function (DUF4200) Sec2p PF06428.6 EPS25634.1 - 0.06 13.2 0.4 0.11 12.4 0.3 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p bZIP_1 PF00170.16 EPS25634.1 - 1.3 9.0 4.2 2.7 8.0 0.6 2.4 2 0 0 2 2 2 0 bZIP transcription factor DUF1385 PF07136.6 EPS25634.1 - 4 6.4 7.4 14 4.7 5.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1385) DUF2404 PF10296.4 EPS25635.1 - 0.0013 18.7 0.0 0.0037 17.3 0.0 1.6 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Innate_immun PF12782.2 EPS25635.1 - 1 8.5 13.5 0.016 14.4 3.5 2.0 2 0 0 2 2 2 0 Invertebrate innate immunity transcript family Optomotor-blind PF11078.3 EPS25638.1 - 0.075 13.4 0.4 0.1 12.9 0.3 1.1 1 0 0 1 1 1 0 Optomotor-blind protein N-terminal region SAICAR_synt PF01259.13 EPS25639.1 - 0.063 12.3 0.0 0.08 12.0 0.0 1.1 1 0 0 1 1 1 0 SAICAR synthetase zf-C2H2_4 PF13894.1 EPS25640.1 - 1.2e-05 25.2 10.3 0.047 14.0 0.4 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EPS25640.1 - 0.00031 20.9 12.6 0.051 13.9 1.1 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EPS25640.1 - 0.0009 19.3 1.9 0.044 13.9 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 EPS25640.1 - 0.0055 16.9 13.2 0.0083 16.3 0.2 3.1 3 0 0 3 3 3 2 Zinc-finger double domain SprT-like PF10263.4 EPS25640.1 - 0.028 14.1 0.4 0.051 13.2 0.2 1.4 1 0 0 1 1 1 0 SprT-like family zf-C2H2_6 PF13912.1 EPS25640.1 - 9.7 6.2 6.4 0.5 10.3 0.3 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger TFIIA PF03153.8 EPS25642.1 - 1.3e-87 295.1 27.9 6.4e-64 217.1 12.6 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit Zip PF02535.17 EPS25642.1 - 0.1 11.5 3.5 0.21 10.5 2.4 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter WD40 PF00400.27 EPS25643.1 - 1.3e-23 81.9 17.6 1.8e-06 27.6 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 EPS25643.1 - 0.00019 21.2 0.4 0.014 15.0 0.1 2.7 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Kelch_5 PF13854.1 EPS25644.1 - 2.1e-28 97.7 0.4 2e-06 27.6 0.0 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_4 PF13418.1 EPS25644.1 - 6.1e-27 93.1 7.8 2.9e-06 26.9 0.0 5.6 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_3 PF13415.1 EPS25644.1 - 4.6e-23 80.7 6.2 2.5e-07 30.6 0.1 5.5 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.20 EPS25644.1 - 7.5e-23 79.8 0.1 8.1e-06 25.2 0.0 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.1 EPS25644.1 - 1.7e-21 75.4 2.3 2.6e-05 24.1 0.1 5.0 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.10 EPS25644.1 - 1.4e-20 72.1 1.2 6.5e-06 25.6 0.0 4.6 4 0 0 4 4 4 4 Kelch motif BTB PF00651.26 EPS25644.1 - 2.6e-09 37.0 0.1 5e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.10 EPS25644.1 - 0.079 12.7 0.0 0.2 11.4 0.0 1.7 1 1 0 1 1 1 0 BTB And C-terminal Kelch Glyco_hydro_1 PF00232.13 EPS25645.1 - 4.3e-157 522.9 0.0 5.2e-157 522.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Sel1 PF08238.7 EPS25646.1 - 3.8e-36 122.6 63.3 8.1e-08 32.6 1.1 12.8 12 1 0 12 12 12 9 Sel1 repeat WD40 PF00400.27 EPS25647.1 - 1.1e-17 63.1 3.0 6.3e-08 32.2 0.1 4.5 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.6 EPS25647.1 - 2.4e-05 24.1 0.1 0.12 12.1 0.0 2.9 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EPS25647.1 - 0.0077 14.5 0.0 0.017 13.4 0.0 1.6 1 0 0 1 1 1 1 Cytochrome D1 heme domain RNA_pol_Rpb1_1 PF04997.7 EPS25648.1 - 1.1e-116 389.8 0.0 2.1e-116 388.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 EPS25648.1 - 1.1e-103 346.2 0.1 2.1e-103 345.3 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EPS25648.1 - 2.6e-69 232.4 0.0 7.9e-69 230.8 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 EPS25648.1 - 1.3e-61 207.6 0.2 2.4e-61 206.7 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 EPS25648.1 - 3.1e-45 153.7 0.0 7.9e-45 152.4 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 EPS25648.1 - 2.8e-43 146.8 6.3 7.5e-43 145.4 4.4 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 EPS25648.1 - 1.3e-36 124.6 0.1 3.6e-36 123.1 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Apolipo_F PF15148.1 EPS25648.1 - 0.24 10.6 0.1 0.64 9.3 0.1 1.6 1 0 0 1 1 1 0 Apolipoprotein F WD40 PF00400.27 EPS25649.1 - 5.1e-17 61.0 0.0 0.00081 19.1 0.0 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat Methyltransf_23 PF13489.1 EPS25650.1 - 7.1e-17 61.5 0.0 1.1e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS25650.1 - 2.1e-07 31.5 0.0 1.2e-06 29.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPS25650.1 - 4.1e-07 30.3 0.0 1e-06 29.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPS25650.1 - 3.3e-06 27.5 0.0 1e-05 25.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPS25650.1 - 1.5e-05 24.5 0.0 2.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EPS25650.1 - 7.3e-05 22.8 0.0 0.00012 22.1 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.9 EPS25650.1 - 0.00017 20.9 0.0 0.00032 20.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EPS25650.1 - 0.0016 17.5 0.0 0.003 16.6 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 EPS25650.1 - 0.002 18.4 0.0 0.016 15.5 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPS25650.1 - 0.0038 17.2 0.0 0.01 15.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EPS25650.1 - 0.014 14.5 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 EPS25650.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Cyclin PF08613.6 EPS25651.1 - 7e-38 130.3 0.5 2.6e-22 79.8 0.2 2.6 2 0 0 2 2 2 2 Cyclin Proteasome PF00227.21 EPS25652.1 - 3.8e-48 163.2 0.2 4.4e-48 163.0 0.2 1.0 1 0 0 1 1 1 1 Proteasome subunit Abhydrolase_5 PF12695.2 EPS25653.1 - 8.4e-23 80.7 0.0 1.4e-22 80.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPS25653.1 - 3.6e-20 72.8 0.0 5.9e-19 68.8 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPS25653.1 - 4.4e-07 29.6 0.0 6.6e-05 22.5 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EPS25653.1 - 6e-06 25.6 0.0 1.4e-05 24.3 0.0 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family FSH1 PF03959.8 EPS25653.1 - 3.4e-05 23.3 0.0 9.2e-05 21.9 0.0 1.7 2 1 0 2 2 2 1 Serine hydrolase (FSH1) AXE1 PF05448.7 EPS25653.1 - 0.00022 19.8 0.0 0.55 8.6 0.0 2.6 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) DLH PF01738.13 EPS25653.1 - 0.0017 17.6 0.0 0.27 10.5 0.0 2.5 2 0 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.6 EPS25653.1 - 0.0048 16.6 0.0 0.43 10.2 0.0 2.2 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Thioesterase PF00975.15 EPS25653.1 - 0.006 16.8 0.0 0.015 15.5 0.0 1.6 2 0 0 2 2 2 1 Thioesterase domain Esterase PF00756.15 EPS25653.1 - 0.0088 15.4 0.0 0.037 13.4 0.0 1.8 2 0 0 2 2 2 1 Putative esterase Abhydrolase_3 PF07859.8 EPS25653.1 - 0.0089 15.6 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF818 PF05677.7 EPS25653.1 - 0.012 14.3 0.0 0.017 13.8 0.0 1.1 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Hydrolase_4 PF12146.3 EPS25653.1 - 0.014 15.2 0.2 0.035 13.9 0.0 1.8 2 0 0 2 2 1 0 Putative lysophospholipase Abhydrolase_2 PF02230.11 EPS25653.1 - 0.019 14.4 0.0 1.3 8.3 0.0 2.5 2 1 1 3 3 3 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.20 EPS25653.1 - 0.029 13.9 0.0 0.049 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2305 PF10230.4 EPS25653.1 - 0.042 13.2 0.0 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) PGAP1 PF07819.8 EPS25653.1 - 0.046 13.3 0.0 0.35 10.4 0.0 2.2 1 1 0 1 1 1 0 PGAP1-like protein DUF1057 PF06342.7 EPS25653.1 - 0.073 11.8 0.0 0.098 11.4 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) R3H PF01424.17 EPS25654.1 - 6.5e-10 38.5 0.1 2.3e-09 36.8 0.0 1.9 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 EPS25654.1 - 4.8e-05 23.2 52.5 0.00032 20.6 7.6 13.1 13 1 0 13 13 13 8 NF-X1 type zinc finger TGS PF02824.16 EPS25654.1 - 0.073 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 TGS domain Virul_fac_BrkB PF03631.10 EPS25654.1 - 0.92 8.8 1.8 1.4 8.2 1.2 1.1 1 0 0 1 1 1 0 Virulence factor BrkB BAF1_ABF1 PF04684.8 EPS25654.1 - 8.5 5.0 11.0 14 4.3 7.7 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor zf-LYAR PF08790.6 EPS25655.1 - 1.7e-14 53.1 2.7 1.7e-14 53.1 1.9 1.9 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger Evr1_Alr PF04777.8 EPS25656.1 - 6.6e-28 96.4 1.2 9.7e-28 95.9 0.5 1.5 1 1 0 1 1 1 1 Erv1 / Alr family Glyco_hydro_92 PF07971.7 EPS25657.1 - 7.5e-165 549.3 0.1 9.1e-165 549.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 MFS_1 PF07690.11 EPS25658.1 - 4.9e-15 55.0 63.6 2.8e-11 42.7 25.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 EPS25660.1 - 8.5e-47 159.5 55.9 3.6e-46 157.5 26.7 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS25660.1 - 5.3e-11 41.7 8.8 5.3e-11 41.7 6.1 2.8 1 1 0 2 2 2 1 Sugar (and other) transporter DUF2583 PF10762.4 EPS25660.1 - 2.7 8.1 5.1 1.5 9.0 0.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2583) G_glu_transpept PF01019.16 EPS25661.1 - 2.1e-164 547.7 0.1 2.6e-164 547.4 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase HhH-GPD PF00730.20 EPS25662.1 - 2.2e-07 31.0 0.0 5.9e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein ADH_N PF08240.7 EPS25664.1 - 7.4e-19 67.5 4.1 7.4e-19 67.5 2.8 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPS25664.1 - 1.5e-09 37.5 0.0 2.7e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EPS25664.1 - 9.9e-05 21.5 0.1 0.00021 20.5 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EPS25664.1 - 0.0012 18.4 2.0 0.0025 17.3 0.2 2.1 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.10 EPS25664.1 - 0.0048 16.7 0.1 0.0088 15.8 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.17 EPS25664.1 - 0.0059 17.1 0.0 0.047 14.2 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.15 EPS25664.1 - 0.03 14.4 0.1 0.095 12.8 0.1 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EPS25664.1 - 0.08 13.2 0.0 1.6 9.0 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding ADH_zinc_N_2 PF13602.1 EPS25664.1 - 0.081 13.8 0.0 0.17 12.7 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase 3HCDH_N PF02737.13 EPS25664.1 - 0.14 11.8 0.1 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Git3 PF11710.3 EPS25665.1 - 8.6e-36 123.3 19.2 9.1e-36 123.3 12.4 1.6 1 1 1 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EPS25665.1 - 2.2e-12 46.5 1.8 4.2e-12 45.6 0.0 2.4 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.6 EPS25665.1 - 0.00056 18.9 20.3 0.00073 18.5 13.5 1.5 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor Glyco_hydro_76 PF03663.9 EPS25666.1 - 1.9e-43 149.3 19.5 2.5e-43 148.8 13.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EPS25666.1 - 0.00018 20.6 1.9 0.038 13.0 0.0 2.5 1 1 1 2 2 2 2 Glycosyl Hydrolase Family 88 Glyco_hydro_47 PF01532.15 EPS25666.1 - 0.0043 15.7 0.0 0.017 13.8 0.0 1.9 1 1 1 2 2 2 1 Glycosyl hydrolase family 47 DUF2190 PF09956.4 EPS25666.1 - 0.059 13.1 0.3 0.46 10.2 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2190) GST_N_2 PF13409.1 EPS25667.1 - 2.6e-09 36.9 0.0 9.1e-09 35.2 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EPS25667.1 - 1.4e-08 34.7 0.0 2.5e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EPS25667.1 - 1.1e-07 32.0 0.0 2e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EPS25667.1 - 3e-05 23.8 0.0 5.8e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EPS25667.1 - 0.0038 17.1 0.1 0.0062 16.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Beta-lactamase PF00144.19 EPS25669.1 - 1.7e-62 211.4 0.0 2.2e-62 211.0 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Xan_ur_permease PF00860.15 EPS25670.1 - 1.3e-22 79.8 34.9 9.8e-22 76.9 22.5 2.7 2 1 0 2 2 2 1 Permease family Tad PF13400.1 EPS25671.1 - 6.2 6.9 5.8 8.6 6.4 4.0 1.2 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like DUF4050 PF13259.1 EPS25672.1 - 0.069 13.0 0.0 0.076 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Sugar_tr PF00083.19 EPS25673.1 - 5.7e-80 269.0 27.3 6.5e-80 268.9 19.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS25673.1 - 1e-30 106.6 29.6 1e-30 106.6 20.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily CorA PF01544.13 EPS25673.1 - 0.58 9.1 1.8 2.3 7.1 1.5 1.7 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein 14-3-3 PF00244.15 EPS25674.1 - 1.5e-10 40.6 0.1 6.8e-10 38.4 0.0 1.8 2 0 0 2 2 2 1 14-3-3 protein DUF2422 PF10337.4 EPS25675.1 - 1.3e-112 376.9 1.7 1.3e-112 376.9 1.1 2.8 3 1 0 3 3 3 2 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 EPS25675.1 - 1e-14 54.5 13.2 1e-14 54.5 9.1 4.0 2 2 2 4 4 4 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 EPS25675.1 - 5.3e-14 52.3 0.0 3.2e-13 49.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) FUSC PF04632.7 EPS25675.1 - 1.1 7.5 19.8 0.0044 15.5 3.2 3.2 3 0 0 3 3 3 0 Fusaric acid resistance protein family DPBB_1 PF03330.13 EPS25676.1 - 1.3e-07 31.5 0.0 2.2e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EPS25676.1 - 0.0028 17.3 0.1 0.004 16.8 0.1 1.3 1 0 0 1 1 1 1 Barwin family DUF1191 PF06697.7 EPS25676.1 - 0.14 10.9 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Sugar_tr PF00083.19 EPS25677.1 - 1.8e-117 392.6 24.7 2.1e-117 392.4 17.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS25677.1 - 4.5e-23 81.5 46.1 1.2e-22 80.1 19.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily EMP24_GP25L PF01105.19 EPS25679.1 - 4.8e-49 166.5 0.1 5.7e-49 166.3 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD TSC22 PF01166.13 EPS25680.1 - 0.069 13.1 10.1 0.62 10.0 0.1 4.8 4 0 0 4 4 4 0 TSC-22/dip/bun family PAM2 PF07145.10 EPS25680.1 - 0.19 11.2 9.2 1.7 8.3 1.3 3.2 3 0 0 3 3 3 0 Ataxin-2 C-terminal region Reo_sigmaC PF04582.7 EPS25680.1 - 3.1 6.8 10.9 0.98 8.5 0.3 3.0 3 0 0 3 3 3 0 Reovirus sigma C capsid protein Glyco_hydro_17 PF00332.13 EPS25681.1 - 8e-30 103.9 0.0 1.8e-29 102.7 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 GLE1 PF07817.8 EPS25682.1 - 7.4e-17 61.1 11.0 8.1e-15 54.4 0.0 3.4 2 1 1 3 3 3 2 GLE1-like protein Caldesmon PF02029.10 EPS25682.1 - 0.28 9.5 41.0 0.43 8.9 28.4 1.3 1 0 0 1 1 1 0 Caldesmon LMBR1 PF04791.11 EPS25682.1 - 0.35 9.3 8.0 0.5 8.8 5.5 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2413 PF10310.4 EPS25682.1 - 2.7 6.6 24.3 4.4 6.0 16.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) SOBP PF15279.1 EPS25682.1 - 3 8.1 5.9 5.2 7.3 4.1 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein Neur_chan_memb PF02932.11 EPS25682.1 - 3.2 7.5 8.3 5.2 6.8 5.8 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SAPS PF04499.10 EPS25682.1 - 6.2 5.3 14.7 9.1 4.7 10.2 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF572 PF04502.8 EPS25682.1 - 8 5.5 31.1 13 4.8 21.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) Borrelia_P83 PF05262.6 EPS25682.1 - 8.4 4.5 35.4 11 4.0 24.5 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein LEA_3 PF03242.8 EPS25684.1 - 0.37 11.0 2.8 0.19 11.9 0.7 1.4 2 0 0 2 2 2 0 Late embryogenesis abundant protein RNB PF00773.14 EPS25685.1 - 2.6e-85 286.5 0.2 1.7e-83 280.6 0.0 2.3 2 0 0 2 2 2 2 RNB domain UQ_con PF00179.21 EPS25686.1 - 9.8e-35 119.0 0.0 1.6e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EPS25686.1 - 0.0011 18.7 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B MMgT PF10270.4 EPS25688.1 - 1.3e-32 112.4 0.0 1.4e-32 112.2 0.0 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter EF1_GNE PF00736.14 EPS25689.1 - 8.9e-32 108.6 3.3 1.7e-31 107.7 2.3 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EPS25689.1 - 1.6e-12 47.3 4.9 1.6e-12 47.3 3.4 3.4 4 0 0 4 4 4 1 Eukaryotic elongation factor 1 beta central acidic region GST_C PF00043.20 EPS25689.1 - 3.3e-05 23.7 0.8 7.3e-05 22.6 0.0 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EPS25689.1 - 4.4e-05 23.2 1.0 0.0017 18.1 0.7 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EPS25689.1 - 0.00021 21.7 0.1 0.00052 20.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DNA_pol3_a_NII PF11490.3 EPS25689.1 - 0.28 10.8 6.3 0.37 10.4 0.2 2.4 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II AAA_2 PF07724.9 EPS25690.1 - 9.3e-45 152.5 0.0 1e-43 149.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EPS25690.1 - 1.2e-25 89.1 0.2 4.2e-25 87.4 0.2 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EPS25690.1 - 1.7e-19 70.3 0.0 7.8e-11 42.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EPS25690.1 - 9.4e-14 51.3 0.4 6.6e-09 35.6 0.0 3.3 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EPS25690.1 - 5.3e-11 42.7 1.0 0.002 18.2 0.0 3.9 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EPS25690.1 - 6.5e-11 42.5 12.1 0.00012 22.1 0.0 5.4 4 2 2 6 6 5 3 AAA ATPase domain Sigma54_activat PF00158.21 EPS25690.1 - 1.3e-07 31.2 0.4 3.5e-05 23.3 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 EPS25690.1 - 2.9e-07 30.4 0.0 0.019 14.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EPS25690.1 - 7.3e-06 25.7 0.0 0.11 12.2 0.0 2.8 2 0 0 2 2 2 2 NACHT domain Arch_ATPase PF01637.13 EPS25690.1 - 1.6e-05 24.7 7.6 0.027 14.1 0.1 4.3 3 2 0 3 3 2 1 Archaeal ATPase AAA_18 PF13238.1 EPS25690.1 - 2.4e-05 24.6 2.3 0.16 12.2 0.1 3.2 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.1 EPS25690.1 - 2.7e-05 24.9 6.6 0.041 14.7 0.1 4.1 3 2 0 3 3 2 2 AAA domain AAA_28 PF13521.1 EPS25690.1 - 3.9e-05 23.6 0.2 0.07 13.0 0.0 3.6 3 1 0 3 3 3 1 AAA domain MobB PF03205.9 EPS25690.1 - 5e-05 23.0 0.0 0.026 14.2 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B TrwB_AAD_bind PF10412.4 EPS25690.1 - 0.0001 21.1 0.1 0.13 10.9 0.0 3.1 3 0 0 3 3 3 1 Type IV secretion-system coupling protein DNA-binding domain AAA_19 PF13245.1 EPS25690.1 - 0.00011 21.8 0.0 0.011 15.5 0.0 3.1 3 0 0 3 3 2 1 Part of AAA domain IstB_IS21 PF01695.12 EPS25690.1 - 0.0003 20.2 0.0 0.69 9.3 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein SRP54 PF00448.17 EPS25690.1 - 0.00031 20.2 0.1 0.049 13.0 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_30 PF13604.1 EPS25690.1 - 0.00071 19.2 1.8 0.19 11.2 0.0 4.2 3 1 1 5 5 3 1 AAA domain RNA_helicase PF00910.17 EPS25690.1 - 0.0011 19.0 0.0 0.69 10.1 0.0 2.8 2 1 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.16 EPS25690.1 - 0.0024 17.0 0.1 2.2 7.3 0.0 3.1 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 EPS25690.1 - 0.0029 16.5 0.3 0.15 11.0 0.2 3.1 2 1 0 2 2 2 1 Protein of unknown function (DUF815) AAA_10 PF12846.2 EPS25690.1 - 0.0041 16.5 1.9 0.18 11.2 0.0 3.6 3 2 0 3 3 3 1 AAA-like domain Zeta_toxin PF06414.7 EPS25690.1 - 0.0042 16.2 0.0 0.2 10.7 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.1 EPS25690.1 - 0.0044 16.4 1.0 0.85 8.9 0.1 3.1 2 2 1 3 3 3 1 AAA domain ABC_tran PF00005.22 EPS25690.1 - 0.0065 16.7 1.9 2.2 8.5 0.0 3.4 3 0 0 3 3 3 1 ABC transporter ATP_bind_1 PF03029.12 EPS25690.1 - 0.0082 15.7 0.1 0.18 11.3 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.1 EPS25690.1 - 0.0097 15.7 0.1 4.5 7.1 0.0 2.8 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EPS25690.1 - 0.013 15.0 0.0 0.75 9.2 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 EPS25690.1 - 0.013 15.1 0.0 0.82 9.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 EPS25690.1 - 0.015 15.1 4.5 2.1 8.1 0.0 3.6 3 2 1 4 4 4 0 Type III restriction enzyme, res subunit DUF258 PF03193.11 EPS25690.1 - 0.02 14.0 0.0 3.8 6.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Miro PF08477.8 EPS25690.1 - 0.031 14.7 0.1 1.8 9.0 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein UPF0079 PF02367.12 EPS25690.1 - 0.031 13.8 0.0 7.7 6.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PhoH PF02562.11 EPS25690.1 - 0.04 13.1 0.1 0.89 8.7 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein UvrD-helicase PF00580.16 EPS25690.1 - 0.12 11.6 4.1 0.31 10.2 0.0 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain LTXXQ PF07813.7 EPS25690.1 - 0.16 12.4 6.6 0.042 14.3 1.6 2.2 2 0 0 2 2 1 0 LTXXQ motif family protein AAA_29 PF13555.1 EPS25690.1 - 0.17 11.4 0.0 9.4 5.8 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain TcdA_TcdB PF12919.2 EPS25690.1 - 0.21 10.0 2.4 0.35 9.2 1.7 1.3 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain CENP-F_leu_zip PF10473.4 EPS25690.1 - 0.75 9.6 17.1 30 4.4 11.8 2.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 EPS25690.1 - 0.88 9.1 13.6 0.67 9.5 8.1 1.8 2 0 0 2 2 1 0 IncA protein AAA_13 PF13166.1 EPS25690.1 - 1.1 7.6 7.9 1.6 7.0 5.5 1.1 1 0 0 1 1 1 0 AAA domain OEP PF02321.13 EPS25690.1 - 1.5 8.3 11.2 3.6 7.1 7.8 1.5 1 0 0 1 1 1 0 Outer membrane efflux protein V_ATPase_I PF01496.14 EPS25690.1 - 1.6 6.4 5.7 2.3 5.9 4.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2968 PF11180.3 EPS25690.1 - 3.2 7.0 13.3 9.3 5.5 8.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) APG6 PF04111.7 EPS25690.1 - 4.5 6.2 10.6 8.1 5.3 7.3 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 EPS25690.1 - 5.1 5.9 10.3 10 4.9 7.1 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DivIC PF04977.10 EPS25690.1 - 6.8 6.2 13.8 3.1 7.3 4.1 2.8 2 1 1 3 3 2 0 Septum formation initiator MutS_V PF00488.16 EPS25691.1 - 2.4e-56 190.7 0.1 4.8e-56 189.8 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EPS25691.1 - 1.9e-18 67.0 0.1 3.3e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 EPS25691.1 - 0.00076 19.6 0.0 0.0016 18.5 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV AAA_22 PF13401.1 EPS25691.1 - 0.1 12.7 0.1 0.43 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain Sas10 PF09368.5 EPS25692.1 - 5.9e-30 103.2 8.8 5.9e-30 103.2 6.1 2.8 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 EPS25692.1 - 4.1e-16 58.9 0.0 2.3e-15 56.5 0.0 2.4 1 0 0 1 1 1 1 Sas10/Utp3/C1D family adh_short PF00106.20 EPS25693.1 - 7.9e-24 84.4 0.1 1.1e-23 83.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPS25693.1 - 3.9e-13 49.4 0.0 6.3e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EPS25693.1 - 5.5e-09 36.1 0.0 9.5e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EPS25693.1 - 1.5e-07 31.1 0.1 4e-07 29.7 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EPS25693.1 - 4.9e-05 23.4 2.5 6.7e-05 22.9 0.6 2.0 2 1 0 2 2 2 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EPS25693.1 - 0.0036 17.0 0.3 0.064 13.0 0.1 2.3 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.15 EPS25693.1 - 0.0052 16.8 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EPS25693.1 - 0.013 15.7 0.0 0.025 14.8 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.14 EPS25693.1 - 0.016 14.2 0.1 0.03 13.3 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain F420_oxidored PF03807.12 EPS25693.1 - 0.035 14.5 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 EPS25693.1 - 0.061 12.2 0.0 0.098 11.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein FA_hydroxylase PF04116.8 EPS25694.1 - 7.8e-11 42.3 11.3 7.8e-11 42.3 7.9 2.5 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Ribosomal_L6e PF01159.14 EPS25695.1 - 7e-39 132.4 1.0 1.1e-38 131.8 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e Proteasom_Rpn13 PF04683.8 EPS25697.1 - 8e-28 96.3 0.0 1.2e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Ion_trans PF00520.26 EPS25698.1 - 1.7e-105 350.5 85.5 4.2e-36 124.0 3.7 5.3 5 1 0 5 5 5 4 Ion transport protein EF-hand_1 PF00036.27 EPS25698.1 - 0.00063 18.8 0.0 0.0022 17.1 0.0 2.0 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EPS25698.1 - 0.0012 18.5 0.0 0.068 13.0 0.0 3.3 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.1 EPS25698.1 - 0.01 15.9 0.0 0.2 11.8 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain pair PKD_channel PF08016.7 EPS25698.1 - 0.31 9.4 61.4 0.3 9.4 1.4 6.9 6 1 1 7 7 7 0 Polycystin cation channel CtaG_Cox11 PF04442.9 EPS25699.1 - 0.075 12.8 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein CtaG/Cox11 SET PF00856.23 EPS25700.1 - 3.1e-23 82.8 0.0 8.9e-23 81.3 0.0 1.9 1 0 0 1 1 1 1 SET domain Pre-SET PF05033.11 EPS25700.1 - 3.8e-09 36.7 2.1 3.8e-09 36.7 1.5 2.0 2 0 0 2 2 2 1 Pre-SET motif Pkinase PF00069.20 EPS25701.1 - 6.1e-76 254.9 0.0 8.9e-76 254.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS25701.1 - 3.8e-40 137.5 0.0 7.5e-40 136.6 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 EPS25701.1 - 1.3e-17 62.8 0.3 2.2e-17 62.2 0.2 1.3 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 EPS25701.1 - 5.1e-06 25.6 0.0 9.9e-06 24.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EPS25701.1 - 5.5e-05 22.2 0.0 0.00065 18.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EPS25701.1 - 0.0015 18.3 0.0 0.016 14.9 0.0 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EPS25701.1 - 0.0022 17.3 0.0 0.0041 16.4 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL RIO1 PF01163.17 EPS25701.1 - 0.026 13.8 0.3 0.089 12.1 0.2 1.8 1 1 0 1 1 1 0 RIO1 family WaaY PF06176.6 EPS25701.1 - 0.031 13.4 0.1 0.05 12.8 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) XFP_N PF09364.5 EPS25704.1 - 1.1e-179 596.8 0.0 1.4e-179 596.5 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.10 EPS25704.1 - 1.1e-83 279.1 0.0 2.4e-83 278.0 0.0 1.6 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.5 EPS25704.1 - 7.4e-83 276.9 0.0 1.1e-82 276.4 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain Fungal_trans PF04082.13 EPS25705.1 - 5.4e-07 28.7 0.1 7.9e-07 28.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_tranf_2_3 PF13641.1 EPS25706.1 - 1.9e-30 106.3 0.0 5e-30 105.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EPS25706.1 - 1.4e-16 60.7 0.7 1.4e-16 60.7 0.5 2.9 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EPS25706.1 - 1.7e-12 47.3 0.0 2.6e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EPS25706.1 - 8.9e-07 28.3 0.0 1.7e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 YrhC PF14143.1 EPS25706.1 - 0.0088 15.9 0.3 0.022 14.7 0.2 1.6 1 0 0 1 1 1 1 YrhC-like protein Cellulose_synt PF03552.9 EPS25706.1 - 0.033 12.4 0.2 4.9 5.3 0.0 2.6 1 1 2 3 3 3 0 Cellulose synthase ACC_central PF08326.7 EPS25707.1 - 0.11 10.6 0.0 0.11 10.6 0.0 1.0 1 0 0 1 1 1 0 Acetyl-CoA carboxylase, central region 4HBT PF03061.17 EPS25708.1 - 5.6e-09 35.9 0.0 8.5e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.1 EPS25708.1 - 0.12 12.8 0.0 0.16 12.4 0.0 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily FA_desaturase PF00487.19 EPS25709.1 - 3.9e-25 88.7 13.7 6.7e-25 87.9 9.5 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EPS25709.1 - 7.3e-07 29.2 0.0 1.3e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) TRAPPC10 PF12584.3 EPS25711.1 - 7.6e-31 106.5 0.0 1.5e-30 105.6 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.3 EPS25711.1 - 0.21 11.0 1.5 0.24 10.8 0.2 1.7 2 0 0 2 2 2 0 Foie gras liver health family 1 Cu_amine_oxid PF01179.15 EPS25712.1 - 4.6e-165 549.3 0.0 5.7e-165 549.0 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 EPS25712.1 - 8.8e-10 38.5 0.0 1.7e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 EPS25712.1 - 9.5e-07 28.8 0.0 1.9e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Invas_SpaK PF03519.9 EPS25712.1 - 0.055 13.3 0.0 5.4 6.9 0.0 2.4 2 0 0 2 2 2 0 Invasion protein B family Polysacc_deac_1 PF01522.16 EPS25713.1 - 1.3e-21 76.4 0.0 4e-21 74.9 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide deacetylase adh_short PF00106.20 EPS25713.1 - 3.9e-18 65.9 0.5 7.2e-18 65.0 0.1 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPS25713.1 - 2.2e-15 57.0 0.3 4.7e-15 56.0 0.2 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EPS25713.1 - 2.6e-05 24.2 0.0 8.8e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 NADH(P)-binding KR PF08659.5 EPS25713.1 - 3.2e-05 23.6 0.2 0.00011 21.8 0.2 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EPS25713.1 - 5.7e-05 22.6 0.0 0.00012 21.6 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPS25713.1 - 0.014 14.1 0.0 0.021 13.5 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF2334 PF10096.4 EPS25713.1 - 0.047 13.0 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Rad51 PF08423.6 EPS25714.1 - 4.8e-25 87.9 0.0 1.1e-24 86.7 0.0 1.4 2 0 0 2 2 2 1 Rad51 AAA_25 PF13481.1 EPS25714.1 - 4.1e-14 52.4 0.0 7.9e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EPS25714.1 - 2.9e-09 36.4 0.0 6e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 KaiC RecA PF00154.16 EPS25714.1 - 5e-06 25.8 0.2 3e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 recA bacterial DNA recombination protein DUF2075 PF09848.4 EPS25714.1 - 0.014 14.3 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PAXNEB PF05625.6 EPS25714.1 - 0.015 14.1 0.2 0.022 13.5 0.1 1.2 1 0 0 1 1 1 0 PAXNEB protein DnaB_C PF03796.10 EPS25714.1 - 0.018 13.9 0.1 0.032 13.1 0.1 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_22 PF13401.1 EPS25714.1 - 0.02 15.0 0.0 0.045 13.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EPS25714.1 - 0.086 13.1 0.1 0.22 11.8 0.1 1.6 1 0 0 1 1 1 0 ABC transporter Pox_A32 PF04665.7 EPS25714.1 - 0.19 10.9 0.1 0.45 9.7 0.1 1.5 1 0 0 1 1 1 0 Poxvirus A32 protein ER-remodelling PF14755.1 EPS25714.1 - 0.61 10.1 9.5 4.4 7.3 2.8 2.5 2 0 0 2 2 2 0 Intracellular membrane remodeller Homeobox_KN PF05920.6 EPS25715.1 - 0.095 12.4 0.1 2 8.1 0.0 2.3 2 0 0 2 2 2 0 Homeobox KN domain Velvet PF11754.3 EPS25716.1 - 1.5e-61 207.5 0.0 2.2e-61 206.9 0.0 1.3 1 0 0 1 1 1 1 Velvet factor Sugar_tr PF00083.19 EPS25718.1 - 2.9e-81 273.3 19.4 3.5e-81 273.0 13.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS25718.1 - 3.4e-22 78.6 36.0 1.3e-19 70.1 14.0 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Cyclase PF04199.8 EPS25722.1 - 5.6e-12 45.6 0.0 9.9e-12 44.8 0.0 1.4 1 0 0 1 1 1 1 Putative cyclase LSM14 PF12701.2 EPS25723.1 - 2e-32 110.8 0.0 3.5e-32 110.0 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 EPS25723.1 - 4.4e-19 68.9 3.4 9.3e-19 67.9 2.3 1.6 1 0 0 1 1 1 1 FDF domain SM-ATX PF14438.1 EPS25723.1 - 7.9e-05 22.5 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain BAF1_ABF1 PF04684.8 EPS25723.1 - 0.5 9.1 4.0 0.75 8.5 2.8 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor API5 PF05918.6 EPS25723.1 - 9.6 4.5 7.1 13 4.1 4.9 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) WD40 PF00400.27 EPS25724.1 - 1.7e-30 103.7 0.9 2.6e-06 27.0 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Gmad1 PF10647.4 EPS25724.1 - 0.0074 15.7 0.1 0.84 8.9 0.0 2.3 2 0 0 2 2 2 2 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.3 EPS25724.1 - 0.0087 14.2 0.3 0.084 10.9 0.1 2.4 2 1 0 2 2 2 1 Nucleoporin Nup120/160 Reg_prop PF07494.6 EPS25724.1 - 0.027 14.4 0.0 2.1 8.6 0.0 3.1 2 0 0 2 2 2 0 Two component regulator propeller Sigma70_r1_2 PF00140.15 EPS25724.1 - 0.86 9.3 5.5 1.6 8.4 3.8 1.5 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 Thioredox_DsbH PF03190.10 EPS25725.1 - 2.5e-71 238.6 0.0 4.2e-71 237.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 EPS25725.1 - 1.9e-07 31.0 0.0 4.3e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like Glyco_hydro_88 PF07470.8 EPS25725.1 - 0.016 14.2 0.1 4.1 6.3 0.1 3.2 3 1 0 3 3 3 0 Glycosyl Hydrolase Family 88 DUF1680 PF07944.7 EPS25725.1 - 0.046 12.0 0.2 1.6 6.8 0.0 2.3 2 0 0 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) C5-epim_C PF06662.8 EPS25725.1 - 0.051 12.8 0.4 10 5.3 0.1 2.5 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus Sigma70_r4 PF04545.11 EPS25725.1 - 0.096 12.0 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 CAP PF00188.21 EPS25727.1 - 4.5e-19 69.1 0.2 6.8e-19 68.5 0.2 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PAT1 PF09770.4 EPS25727.1 - 7.8 4.5 9.8 9.8 4.2 6.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FAD_binding_3 PF01494.14 EPS25728.1 - 8.8e-22 77.6 0.0 9.7e-11 41.3 0.0 2.4 2 1 0 2 2 2 2 FAD binding domain SE PF08491.5 EPS25728.1 - 0.0013 17.6 0.0 0.0019 17.0 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_3 PF13738.1 EPS25728.1 - 0.0016 18.5 0.0 0.075 13.0 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPS25728.1 - 0.004 17.0 0.5 0.011 15.6 0.3 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPS25728.1 - 0.0044 17.3 0.1 0.011 16.1 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPS25728.1 - 0.0049 16.8 0.3 0.014 15.4 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EPS25728.1 - 0.032 14.0 0.3 0.21 11.3 0.2 2.2 1 1 0 1 1 1 0 FAD-NAD(P)-binding Thi4 PF01946.12 EPS25728.1 - 0.054 12.5 0.0 0.099 11.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family DAO PF01266.19 EPS25728.1 - 0.2 10.5 0.5 0.66 8.8 0.4 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Med11 PF10280.4 EPS25729.1 - 0.085 12.9 0.1 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Mediator complex protein Carn_acyltransf PF00755.15 EPS25730.1 - 2.8e-168 560.6 0.0 1.9e-152 508.4 0.0 2.0 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase Ligase_CoA PF00549.14 EPS25732.1 - 2.6e-35 121.2 2.0 1.1e-17 64.0 0.1 2.4 2 0 0 2 2 2 2 CoA-ligase CoA_binding PF02629.14 EPS25732.1 - 4.9e-17 62.2 0.2 1.3e-16 60.8 0.1 1.8 1 0 0 1 1 1 1 CoA binding domain Succ_CoA_lig PF13607.1 EPS25732.1 - 1.3e-10 40.9 0.1 7.9e-09 35.2 0.0 2.5 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EPS25732.1 - 0.024 14.8 1.1 0.045 13.9 0.1 2.0 2 0 0 2 2 2 0 CoA binding domain Rad60-SLD PF11976.3 EPS25734.1 - 7.8e-21 73.5 0.4 9.8e-21 73.2 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EPS25734.1 - 1.5e-08 33.9 0.1 1.8e-08 33.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family SRP9-21 PF05486.7 EPS25734.1 - 0.065 12.9 0.0 0.083 12.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) DUF1903 PF08991.5 EPS25735.1 - 2.6e-23 81.9 9.8 3.1e-23 81.7 6.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 EPS25735.1 - 0.0026 17.6 7.0 0.0026 17.6 4.8 1.6 2 0 0 2 2 2 1 CHCH domain Cmc1 PF08583.5 EPS25735.1 - 0.73 9.6 7.6 0.37 10.5 2.9 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Brr6_like_C_C PF10104.4 EPS25735.1 - 1.2 8.6 4.3 1.3 8.5 3.0 1.1 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain Nup84_Nup100 PF04121.8 EPS25736.1 - 2.8e-55 187.2 0.2 3.6e-54 183.6 0.2 2.7 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 E1-E2_ATPase PF00122.15 EPS25737.1 - 2.4e-61 206.6 2.0 2.4e-61 206.6 1.4 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EPS25737.1 - 7.3e-44 149.4 8.6 7.3e-44 149.4 5.9 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EPS25737.1 - 1.1e-27 97.8 0.2 1.3e-26 94.4 0.0 2.6 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPS25737.1 - 2e-19 69.2 0.0 4.1e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EPS25737.1 - 1.2e-13 51.6 0.0 3e-13 50.3 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EPS25737.1 - 1.7e-10 40.2 0.4 4e-09 35.8 0.0 2.5 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EPS25737.1 - 3.6e-05 23.4 2.2 0.00027 20.5 1.3 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase D-ser_dehydrat PF14031.1 EPS25738.1 - 1.1e-22 80.0 0.2 2.3e-22 78.9 0.1 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 EPS25738.1 - 8.8e-12 45.0 0.0 1.4e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Transp_cyt_pur PF02133.10 EPS25739.1 - 2.6e-17 62.5 31.4 3.8e-17 61.9 21.8 1.3 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF2236 PF09995.4 EPS25740.1 - 3.2e-13 49.5 2.3 4.4e-13 49.0 0.2 2.2 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) AGT PF11440.3 EPS25740.1 - 0.055 12.3 0.0 0.085 11.7 0.0 1.2 1 0 0 1 1 1 0 DNA alpha-glucosyltransferase Tubulin PF00091.20 EPS25741.1 - 3.1e-69 233.1 0.0 5.3e-69 232.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EPS25741.1 - 6.7e-50 168.3 0.1 1.2e-49 167.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EPS25741.1 - 2.2e-05 24.5 0.0 5.7e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EPS25741.1 - 0.0038 16.7 0.0 0.0066 15.9 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain RRM_1 PF00076.17 EPS25742.1 - 5.1e-16 58.0 0.0 1.5e-06 27.7 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS25742.1 - 7.9e-12 44.9 0.0 5.2e-06 26.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS25742.1 - 1.7e-10 40.5 0.0 1.8e-07 30.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EZH2_WD-Binding PF11616.3 EPS25742.1 - 0.13 12.1 1.0 0.39 10.6 0.4 2.0 2 0 0 2 2 2 0 WD repeat binding protein EZH2 Ammonium_transp PF00909.16 EPS25743.1 - 2.5e-121 404.9 30.8 2.8e-121 404.7 21.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Pkinase PF00069.20 EPS25744.1 - 1.9e-65 220.6 0.0 3.3e-65 219.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS25744.1 - 1e-35 123.0 0.0 2.1e-34 118.7 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPS25744.1 - 3.4e-07 29.5 0.2 1.3e-05 24.3 0.1 2.3 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EPS25744.1 - 0.0023 17.6 0.0 0.0057 16.4 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EPS25744.1 - 0.018 13.8 0.0 0.032 13.0 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Vac_ImportDeg PF09783.4 EPS25745.1 - 3.3e-70 235.1 2.8 4.2e-70 234.8 1.9 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Herpes_gI PF01688.12 EPS25745.1 - 0.03 13.4 0.0 0.048 12.7 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein I Mago_nashi PF02792.9 EPS25746.1 - 4.3e-76 253.4 0.3 4.9e-76 253.2 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein Adaptin_N PF01602.15 EPS25747.1 - 2.9e-90 303.0 10.6 5.2e-90 302.2 7.4 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 EPS25747.1 - 2.3e-62 208.4 0.0 8e-62 206.7 0.0 2.0 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 EPS25747.1 - 6.5e-62 207.3 0.7 1.4e-61 206.2 0.5 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 EPS25747.1 - 3.8e-11 43.1 10.7 3.9e-06 27.0 0.0 4.7 2 2 1 4 4 4 3 HEAT repeats Cnd1 PF12717.2 EPS25747.1 - 0.00015 21.6 10.1 0.007 16.2 0.0 3.9 3 1 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EPS25747.1 - 0.00032 20.5 0.5 0.5 10.5 0.0 4.2 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.1 EPS25747.1 - 0.005 17.2 4.3 0.32 11.5 0.1 4.7 4 1 1 5 5 5 2 HEAT-like repeat AP4E_app_platf PF14807.1 EPS25747.1 - 0.025 14.8 0.2 0.094 12.9 0.1 2.0 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform Arm PF00514.18 EPS25747.1 - 0.16 11.8 1.5 3.6 7.5 0.0 3.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DAGK_cat PF00781.19 EPS25748.1 - 3.7e-22 78.1 0.0 6.2e-22 77.4 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Nop52 PF05997.7 EPS25749.1 - 2.3e-43 148.1 0.0 1e-35 123.1 0.0 2.1 2 0 0 2 2 2 2 Nucleolar protein,Nop52 NOT2_3_5 PF04153.13 EPS25749.1 - 0.081 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 NOT2 / NOT3 / NOT5 family ABC2_membrane PF01061.19 EPS25750.1 - 4.6e-79 264.4 44.8 1.4e-44 151.7 15.9 3.1 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 EPS25750.1 - 3.7e-39 132.5 6.5 1.5e-33 114.4 0.1 3.3 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.22 EPS25750.1 - 3.2e-37 127.8 0.0 1.6e-18 67.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 EPS25750.1 - 1.9e-19 69.5 0.0 1.1e-18 67.0 0.0 2.3 2 0 0 2 2 2 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EPS25750.1 - 4.1e-08 32.8 0.0 0.00015 21.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 EPS25750.1 - 1.1e-07 31.1 42.8 0.00029 19.9 9.4 2.4 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.1 EPS25750.1 - 5.7e-06 26.4 1.4 0.004 17.1 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EPS25750.1 - 1.3e-05 24.4 0.0 0.0059 15.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EPS25750.1 - 6e-05 23.8 0.0 0.057 14.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EPS25750.1 - 8.8e-05 22.8 0.0 0.032 14.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EPS25750.1 - 0.00011 21.6 0.8 0.0036 16.7 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EPS25750.1 - 0.00034 20.5 0.1 0.039 13.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EPS25750.1 - 0.0017 17.8 2.4 0.04 13.4 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_19 PF13245.1 EPS25750.1 - 0.0068 16.1 0.1 2.3 8.0 0.1 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EPS25750.1 - 0.0088 15.6 0.1 0.65 9.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EPS25750.1 - 0.0093 16.1 0.4 0.95 9.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EPS25750.1 - 0.022 14.7 0.0 0.23 11.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 EPS25750.1 - 0.022 13.9 0.0 0.28 10.3 0.0 2.5 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain NACHT PF05729.7 EPS25750.1 - 0.024 14.3 2.0 3.2 7.3 0.2 2.7 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.18 EPS25750.1 - 0.058 13.3 0.1 7.3 6.5 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.1 EPS25750.1 - 0.16 11.9 0.1 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EPS25750.1 - 0.46 10.1 3.0 1.4 8.5 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ubiquitin PF00240.18 EPS25751.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family Ribosomal_L39 PF00832.15 EPS25751.1 - 5.6 6.5 6.1 32 4.0 0.1 2.4 2 0 0 2 2 2 0 Ribosomal L39 protein DUF1604 PF07713.8 EPS25752.1 - 2.1e-39 133.1 7.0 1.8e-38 130.2 1.5 3.4 4 0 0 4 4 4 1 Protein of unknown function (DUF1604) G-patch PF01585.18 EPS25752.1 - 9.6e-07 28.4 2.3 2.8e-06 26.9 1.6 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EPS25752.1 - 0.0021 17.8 3.4 0.0084 15.9 0.1 2.9 2 0 0 2 2 2 1 DExH-box splicing factor binding site Glyco_transf_90 PF05686.7 EPS25753.1 - 6.7e-16 57.9 4.3 4.5e-10 38.7 0.6 3.9 2 1 0 2 2 2 2 Glycosyl transferase family 90 Sugar_tr PF00083.19 EPS25755.1 - 1.7e-92 310.3 23.6 2e-92 310.1 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS25755.1 - 4.8e-26 91.3 18.2 4.8e-26 91.3 12.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Pox_A14 PF05767.7 EPS25755.1 - 0.012 15.5 1.1 0.051 13.5 0.2 2.6 1 1 1 2 2 2 0 Poxvirus virion envelope protein A14 ATG2_CAD PF13329.1 EPS25755.1 - 0.09 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Autophagy-related protein 2 CAD motif DUF3804 PF12707.2 EPS25755.1 - 0.09 12.3 0.0 3.7 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3804) TIG PF01833.19 EPS25756.1 - 1.6e-11 44.0 0.1 6e-11 42.1 0.1 2.0 1 0 0 1 1 1 1 IPT/TIG domain Ank PF00023.25 EPS25756.1 - 6e-11 41.5 7.7 5.5e-05 22.7 1.6 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 EPS25756.1 - 9.8e-11 41.8 0.1 2.7e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPS25756.1 - 7.5e-08 32.6 0.8 2.6e-07 30.9 0.4 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPS25756.1 - 1.4e-07 31.0 1.6 0.03 14.5 0.6 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EPS25756.1 - 1.9e-07 31.0 9.5 6.9e-07 29.3 1.5 3.7 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EPS25757.1 - 8.1e-18 64.5 0.0 1.3e-10 41.5 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EPS25757.1 - 4.9e-16 57.6 0.0 1e-05 25.0 0.0 4.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 EPS25757.1 - 3e-10 40.3 0.1 0.074 13.5 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPS25757.1 - 2.8e-09 36.3 0.0 0.00046 20.1 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EPS25757.1 - 1.6e-08 34.5 0.2 2.9e-06 27.3 0.0 3.4 1 1 3 4 4 4 1 Ankyrin repeats (many copies) NYN PF01936.13 EPS25758.1 - 7.7e-32 110.5 0.0 1.1e-31 110.0 0.0 1.2 1 0 0 1 1 1 1 NYN domain OST-HTH PF12872.2 EPS25758.1 - 6e-20 70.8 0.0 1.2e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 OST-HTH/LOTUS domain DUF3576 PF12100.3 EPS25759.1 - 0.15 12.1 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3576) DUF2065 PF09838.4 EPS25760.1 - 0.077 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2065) Glyco_hydro_61 PF03443.9 EPS25762.1 - 6.9e-85 284.2 0.2 1.3e-84 283.3 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 SUI1 PF01253.17 EPS25763.1 - 1.4e-16 60.0 0.2 2.9e-16 59.0 0.1 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 Dabb PF07876.7 EPS25764.1 - 1.1e-16 61.0 0.0 1.2e-16 60.9 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain La PF05383.12 EPS25765.1 - 4.3e-18 64.8 0.0 7.2e-18 64.1 0.0 1.4 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 EPS25765.1 - 2.5e-08 33.4 0.1 6.6e-08 32.0 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS25765.1 - 2.1e-07 30.8 0.0 5.2e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS25765.1 - 0.074 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Chitin_synth_2 PF03142.10 EPS25766.1 - 5.3e-21 74.6 1.5 5.3e-21 74.6 1.1 2.5 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EPS25766.1 - 1.2e-17 64.2 3.0 1.2e-17 64.2 2.1 2.7 2 2 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EPS25766.1 - 1.7e-15 57.4 0.0 3.9e-15 56.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EPS25766.1 - 0.0042 16.7 0.0 1.8 8.2 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 HSP70 PF00012.15 EPS25767.1 - 6.6e-166 552.7 0.8 6.6e-166 552.7 0.5 2.0 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EPS25767.1 - 3.2e-10 39.1 0.0 1.2e-09 37.2 0.0 1.8 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 EPS25767.1 - 0.0054 16.5 6.1 1.3 8.9 0.5 3.7 3 2 0 3 3 3 2 Cell division protein FtsA Rad52_Rad22 PF04098.10 EPS25767.1 - 0.062 13.0 5.2 9 6.0 0.0 2.5 2 0 0 2 2 2 0 Rad52/22 family double-strand break repair protein Metal_resist PF13801.1 EPS25767.1 - 0.34 10.9 10.9 0.49 10.3 0.1 2.4 2 0 0 2 2 2 0 Heavy-metal resistance V_ATPase_I PF01496.14 EPS25767.1 - 8.7 4.0 9.8 15 3.2 6.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LicD PF04991.8 EPS25768.1 - 2.8e-35 122.3 5.6 4.5e-34 118.3 3.9 2.0 1 1 0 1 1 1 1 LicD family WLM PF08325.5 EPS25769.1 - 2.2e-46 158.1 0.1 8.8e-46 156.1 0.0 1.8 2 0 0 2 2 2 1 WLM domain SprT-like PF10263.4 EPS25769.1 - 9.3e-05 22.1 0.0 0.00015 21.4 0.0 1.4 1 0 0 1 1 1 1 SprT-like family DUF45 PF01863.12 EPS25769.1 - 0.00097 18.9 0.4 0.0019 18.0 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function DUF45 Thiolase_N PF00108.18 EPS25770.1 - 1.1e-71 240.9 0.0 1.8e-71 240.2 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EPS25770.1 - 2e-41 140.2 2.7 2.2e-41 140.1 0.3 2.1 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EPS25770.1 - 0.016 14.7 0.4 0.047 13.1 0.1 2.0 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EPS25770.1 - 0.036 13.7 0.0 6.1 6.5 0.0 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.5 EPS25770.1 - 0.044 13.7 0.0 0.14 12.2 0.0 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Stathmin PF00836.14 EPS25771.1 - 0.045 13.3 0.8 0.079 12.5 0.6 1.4 1 0 0 1 1 1 0 Stathmin family DASH_Ask1 PF08655.5 EPS25772.1 - 3.8e-33 113.1 0.0 7.1e-33 112.2 0.0 1.5 1 0 0 1 1 1 1 DASH complex subunit Ask1 FAD_binding_3 PF01494.14 EPS25773.1 - 2.4e-20 72.8 0.1 2.2e-12 46.7 0.1 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 EPS25773.1 - 9.2e-05 22.3 0.0 0.00049 20.0 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HIG_1_N PF04588.8 EPS25774.1 - 7e-09 35.2 0.4 1.3e-08 34.4 0.3 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region SGT1 PF07093.6 EPS25774.1 - 0.00016 20.2 1.1 0.00017 20.1 0.8 1.0 1 0 0 1 1 1 1 SGT1 protein INCA1 PF15142.1 EPS25774.1 - 0.097 12.4 0.2 0.18 11.5 0.1 1.5 1 0 0 1 1 1 0 INCA1 DUF3169 PF11368.3 EPS25774.1 - 0.39 9.8 0.0 0.39 9.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) Med26 PF08711.6 EPS25775.1 - 4.4e-13 48.5 0.2 8e-13 47.6 0.1 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Tom5 PF10642.4 EPS25776.1 - 1.3e-19 69.6 0.2 1.3e-19 69.5 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Pombe_5TM PF09437.5 EPS25776.1 - 0.12 11.7 0.0 0.13 11.6 0.0 1.0 1 0 0 1 1 1 0 Pombe specific 5TM protein Nup54 PF13874.1 EPS25777.1 - 5.8e-41 139.4 0.1 5.8e-41 139.4 0.1 2.0 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 EPS25777.1 - 1.7e-12 47.5 77.6 3.9e-08 33.5 30.7 2.3 1 1 1 2 2 2 2 Nucleoporin FG repeat region DUF4200 PF13863.1 EPS25777.1 - 6 6.8 11.3 13 5.7 2.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) CHCH PF06747.8 EPS25778.1 - 0.0014 18.4 3.4 0.0014 18.4 2.4 2.6 3 0 0 3 3 3 2 CHCH domain Pet191_N PF10203.4 EPS25778.1 - 0.068 13.2 9.6 2.1 8.4 4.6 2.8 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 EPS25778.1 - 0.24 11.1 13.1 0.31 10.8 2.2 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CD45 PF12567.3 EPS25778.1 - 0.27 11.0 8.4 0.062 13.1 3.2 1.8 1 1 1 2 2 2 0 Leukocyte receptor CD45 COX6B PF02297.12 EPS25778.1 - 5.2 7.1 9.9 3.3 7.7 0.6 2.2 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb ACBP PF00887.14 EPS25779.1 - 1.7e-26 91.6 0.0 3.1e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein Macoilin PF09726.4 EPS25779.1 - 0.31 9.2 6.3 0.38 8.9 4.4 1.2 1 0 0 1 1 1 0 Transmembrane protein Lin-8 PF03353.10 EPS25779.1 - 0.34 10.1 7.2 0.56 9.4 5.0 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Hep_59 PF07052.6 EPS25779.1 - 0.5 10.7 4.4 0.7 10.2 1.6 2.2 2 1 1 3 3 3 0 Hepatocellular carcinoma-associated antigen 59 CDC45 PF02724.9 EPS25779.1 - 2.7 5.8 10.9 4 5.3 7.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.6 EPS25779.1 - 10 3.8 6.6 15 3.2 4.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen AA_permease_2 PF13520.1 EPS25780.1 - 7.9e-58 195.9 54.8 9.7e-58 195.6 38.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPS25780.1 - 7.2e-32 110.3 50.3 9.7e-32 109.9 34.8 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3493 PF11998.3 EPS25780.1 - 1.1 9.2 0.0 1.1 9.2 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3493) JmjC PF02373.17 EPS25781.1 - 4.4e-37 126.8 1.8 5.2e-37 126.5 0.3 1.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.1 EPS25781.1 - 2.4e-18 66.1 2.8 4.2e-18 65.3 2.0 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EPS25781.1 - 1.6e-17 63.4 3.1 3.3e-17 62.3 2.1 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain JmjN PF02375.12 EPS25781.1 - 1.5e-15 56.4 0.7 3.3e-15 55.2 0.5 1.6 1 0 0 1 1 1 1 jmjN domain 4HBT_2 PF13279.1 EPS25782.1 - 7e-11 42.6 0.0 1.2e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Cyclase PF04199.8 EPS25784.1 - 3.2e-08 33.4 0.1 6.6e-08 32.4 0.0 1.5 1 1 0 1 1 1 1 Putative cyclase RHD3 PF05879.7 EPS25785.1 - 0 1070.0 0.0 0 1069.7 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) Dynamin_N PF00350.18 EPS25785.1 - 8.2e-07 28.9 0.0 1.6e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GBP PF02263.14 EPS25785.1 - 8.5e-07 28.2 0.3 1.4e-06 27.5 0.2 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.18 EPS25785.1 - 0.00021 21.2 0.0 0.00042 20.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EPS25785.1 - 0.00027 21.4 0.1 0.00058 20.3 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 EPS25785.1 - 0.00055 19.9 0.0 0.0013 18.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain Septin PF00735.13 EPS25785.1 - 0.016 14.2 0.1 0.036 13.0 0.1 1.5 1 0 0 1 1 1 0 Septin Fungal_trans PF04082.13 EPS25786.1 - 0.00069 18.5 0.1 0.0035 16.2 0.0 2.0 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS25786.1 - 0.0073 16.1 7.2 0.014 15.2 5.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GTP_EFTU PF00009.22 EPS25787.1 - 3e-60 202.8 0.1 4e-60 202.4 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EPS25787.1 - 5.6e-22 77.7 0.0 2.7e-21 75.5 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EPS25787.1 - 1.9e-17 63.1 2.8 2.1e-17 63.0 1.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EPS25787.1 - 8.9e-06 25.6 0.0 1.6e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EPS25787.1 - 0.0013 19.1 0.0 0.0023 18.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU_D4 PF14578.1 EPS25787.1 - 0.0016 18.0 0.1 0.0052 16.4 0.1 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 4 PduV-EutP PF10662.4 EPS25787.1 - 0.04 13.4 0.2 3.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation IF3_C PF00707.17 EPS25788.1 - 3.7e-16 58.6 2.7 6.8e-16 57.7 1.9 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.1 EPS25788.1 - 2.8e-06 26.8 6.2 7.2e-06 25.4 3.9 1.9 1 1 1 2 2 2 1 Mitochondrial translation initiation factor IF3_N PF05198.11 EPS25788.1 - 6.6e-06 25.9 0.1 1.6e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain DUF1938 PF09153.5 EPS25788.1 - 0.027 14.2 0.1 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1938) ALO PF04030.9 EPS25788.1 - 0.072 12.6 0.0 0.096 12.2 0.0 1.3 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase GDA1_CD39 PF01150.12 EPS25789.1 - 5.2e-95 318.4 0.0 7.2e-95 318.0 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family BLVR PF06375.6 EPS25790.1 - 0.0025 17.6 18.6 0.0036 17.1 12.9 1.2 1 0 0 1 1 1 1 Bovine leukaemia virus receptor (BLVR) Peptidase_S49_N PF08496.5 EPS25790.1 - 0.0054 16.5 11.0 0.0074 16.0 7.6 1.2 1 0 0 1 1 1 1 Peptidase family S49 N-terminal RNA_polI_A34 PF08208.6 EPS25790.1 - 0.0097 15.5 18.7 0.012 15.2 13.0 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 Rtf2 PF04641.7 EPS25790.1 - 0.022 13.9 11.7 0.032 13.4 8.1 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger GAGA_bind PF06217.7 EPS25790.1 - 0.11 12.4 8.8 0.14 12.1 6.1 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family YqfQ PF14181.1 EPS25790.1 - 0.15 12.1 8.6 0.21 11.6 6.0 1.2 1 0 0 1 1 1 0 YqfQ-like protein Med19 PF10278.4 EPS25790.1 - 0.25 10.9 22.1 0.41 10.3 15.3 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 TAF1D PF15333.1 EPS25790.1 - 0.27 10.9 14.1 0.38 10.4 9.8 1.2 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D Agouti PF05039.7 EPS25790.1 - 0.29 11.4 6.4 0.48 10.8 4.5 1.4 1 0 0 1 1 1 0 Agouti protein DUF1168 PF06658.7 EPS25790.1 - 0.56 9.7 21.0 0.78 9.2 14.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) OAD_gamma PF04277.8 EPS25790.1 - 0.95 9.8 5.3 1.6 9.1 3.7 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DUF3464 PF11947.3 EPS25790.1 - 2 7.8 8.2 2.8 7.3 5.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Pectate_lyase_3 PF12708.2 EPS25791.1 - 2.2e-42 145.7 23.0 4e-34 118.6 6.5 3.3 4 1 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EPS25791.1 - 0.024 14.0 3.0 0.99 8.9 0.0 3.1 3 0 0 3 3 3 0 N terminal extension of bacteriophage endosialidase DUF4598 PF15370.1 EPS25792.1 - 1.6e-37 128.2 7.2 1.6e-37 128.2 5.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4598) COMPASS-Shg1 PF05205.7 EPS25793.1 - 2.6e-30 104.8 2.5 2.8e-30 104.7 0.4 2.1 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component shg1 MIP-T3 PF10243.4 EPS25793.1 - 0.00063 18.3 31.8 0.0011 17.6 22.0 1.4 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CAF-1_p150 PF11600.3 EPS25793.1 - 4.9 6.4 56.5 0.12 11.7 33.9 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Cation_efflux PF01545.16 EPS25795.1 - 1.3e-32 113.0 5.4 1.6e-32 112.6 3.7 1.1 1 0 0 1 1 1 1 Cation efflux family zf-rbx1 PF12678.2 EPS25796.1 - 4.1e-09 36.4 0.3 8.1e-09 35.4 0.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EPS25796.1 - 2e-08 33.9 10.4 3.3e-07 30.0 7.2 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EPS25796.1 - 6.8e-07 28.8 1.2 1.2e-06 28.0 0.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPS25796.1 - 7.5e-07 28.7 2.4 1.4e-06 27.9 1.0 2.0 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EPS25796.1 - 1.1e-05 24.9 5.5 5.4e-05 22.7 3.8 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPS25796.1 - 9.2e-05 22.3 2.6 9.2e-05 22.3 1.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EPS25796.1 - 0.0064 16.3 1.6 0.018 14.8 1.1 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2921 PF11145.3 EPS25796.1 - 0.035 11.8 0.3 0.056 11.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) zf-RING_UBOX PF13445.1 EPS25796.1 - 0.51 10.1 4.0 0.45 10.2 0.8 2.3 1 1 1 2 2 2 0 RING-type zinc-finger FANCL_C PF11793.3 EPS25796.1 - 5.3 7.0 6.4 24 4.9 4.5 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain GCV_H PF01597.14 EPS25797.1 - 7.5e-36 122.4 0.9 8.9e-36 122.2 0.6 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Ribosomal_S6 PF01250.12 EPS25798.1 - 2.6e-06 27.2 0.0 3.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 Abhydrolase_5 PF12695.2 EPS25799.1 - 1.2e-05 25.1 0.0 3.1e-05 23.7 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EPS25799.1 - 0.00023 20.8 0.0 0.00045 19.8 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 EPS25799.1 - 0.00025 20.4 0.0 0.00042 19.6 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EPS25799.1 - 0.0013 18.7 2.5 0.0029 17.5 1.7 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EPS25799.1 - 0.01 15.4 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold LCAT PF02450.10 EPS25799.1 - 0.038 12.9 0.0 0.059 12.3 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase ATP-synt_ab PF00006.20 EPS25799.1 - 0.14 11.5 0.1 0.47 9.9 0.0 1.8 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Chs3p PF12271.3 EPS25800.1 - 5.9e-138 458.7 16.5 6.7e-138 458.5 11.4 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit Acetyltransf_1 PF00583.19 EPS25805.1 - 2.3e-09 37.1 0.0 3.9e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EPS25805.1 - 3.8e-07 30.2 0.0 8.9e-07 29.0 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EPS25805.1 - 5.7e-07 29.6 0.0 1.1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPS25805.1 - 0.00019 21.2 0.2 0.033 14.0 0.0 3.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPS25805.1 - 0.00039 20.1 0.0 0.00067 19.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 EPS25805.1 - 0.00068 19.4 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 EPS25805.1 - 0.019 14.8 0.0 0.092 12.6 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF3676 PF12429.3 EPS25806.1 - 0.71 9.4 5.4 0.81 9.2 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3676) Arrestin_C PF02752.17 EPS25807.1 - 5.2e-22 78.4 0.3 2.6e-21 76.1 0.0 2.3 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EPS25807.1 - 1.6e-08 34.4 0.0 6.6e-05 22.7 0.0 2.8 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain RRM_1 PF00076.17 EPS25810.1 - 2.5e-61 203.2 0.0 1.4e-21 75.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS25810.1 - 1.2e-45 153.3 0.0 8.7e-15 54.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS25810.1 - 2.2e-30 104.2 0.0 1.7e-10 40.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPS25810.1 - 4.2e-05 23.2 0.0 0.04 13.6 0.0 3.3 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.5 EPS25810.1 - 0.026 14.4 0.0 1.9 8.5 0.0 2.4 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) RRM_3 PF08777.6 EPS25810.1 - 0.03 14.1 0.0 1.6 8.5 0.0 2.6 3 0 0 3 3 3 0 RNA binding motif Glyco_hydro_114 PF03537.8 EPS25810.1 - 0.033 13.9 0.0 10 5.9 0.0 2.6 2 0 0 2 2 2 0 Glycoside-hydrolase family GH114 RNA_bind PF08675.6 EPS25810.1 - 0.08 12.9 0.0 5 7.1 0.0 2.4 2 0 0 2 2 2 0 RNA binding domain DUF2370 PF10176.4 EPS25811.1 - 0.16 11.3 0.1 0.16 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) GATase_4 PF13230.1 EPS25812.1 - 2.3e-14 52.7 0.0 4.7e-13 48.4 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 EPS25812.1 - 1.6e-09 37.7 0.0 4.2e-09 36.4 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EPS25812.1 - 2.3e-06 26.5 0.0 0.00068 18.4 0.1 2.5 3 0 0 3 3 3 2 Glutamine amidotransferases class-II Dynamin_N PF00350.18 EPS25813.1 - 1.8e-43 148.2 0.0 4e-43 147.1 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EPS25813.1 - 2.1e-14 53.0 0.1 6.4e-10 38.2 0.0 2.4 2 0 0 2 2 2 2 Dynamin central region MMR_HSR1 PF01926.18 EPS25813.1 - 0.0033 17.3 0.0 0.015 15.2 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EPS25813.1 - 0.0037 17.7 0.0 0.0095 16.4 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein SRI PF08236.6 EPS25813.1 - 0.026 14.4 0.2 0.073 13.0 0.2 1.7 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain DUF2344 PF10105.4 EPS25813.1 - 0.073 12.5 0.3 11 5.4 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2344) FtsJ PF01728.14 EPS25814.1 - 1.3e-12 48.1 0.0 2.2e-12 47.3 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 EPS25814.1 - 0.0032 18.0 0.0 0.011 16.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPS25814.1 - 0.057 13.7 0.0 0.19 12.0 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_26 PF13659.1 EPS25814.1 - 0.059 13.4 0.0 0.14 12.2 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 EPS25814.1 - 0.15 12.6 0.2 0.92 10.0 0.1 2.2 1 1 0 1 1 1 0 Methyltransferase domain Pyr_redox_2 PF07992.9 EPS25815.1 - 2e-27 96.4 0.0 4.3e-16 59.3 0.0 3.4 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPS25815.1 - 5e-13 49.2 0.0 2.9e-11 43.6 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPS25815.1 - 6.5e-05 23.0 0.1 1.3 8.9 0.2 3.4 3 1 1 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EPS25815.1 - 0.13 10.7 2.7 0.41 9.0 0.1 2.7 2 1 1 3 3 3 0 HI0933-like protein Glyco_hydro_10 PF00331.15 EPS25816.1 - 1.7e-85 286.8 0.1 1.9e-85 286.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Sugar_tr PF00083.19 EPS25817.1 - 1.3e-88 297.5 20.0 1.6e-88 297.2 13.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS25817.1 - 2.3e-25 89.0 17.2 2.3e-25 89.0 11.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EPS25817.1 - 0.00024 19.6 30.3 0.00051 18.5 4.3 3.5 2 2 0 3 3 3 2 MFS/sugar transport protein Gate PF07670.9 EPS25817.1 - 0.013 15.4 4.7 0.013 15.4 3.3 2.8 3 0 0 3 3 3 0 Nucleoside recognition NfeD PF01957.13 EPS25817.1 - 1.4 9.0 6.7 13 5.9 1.3 3.0 2 1 0 2 2 2 0 NfeD-like C-terminal, partner-binding Cyclin PF08613.6 EPS25820.1 - 7.9e-17 62.0 0.1 1.2e-16 61.4 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EPS25820.1 - 8.1e-05 22.1 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ribosomal_L18e PF00828.14 EPS25821.1 - 1.2e-15 57.9 0.1 2.1e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Pkinase PF00069.20 EPS25822.1 - 1.6e-48 165.1 0.0 2.1e-48 164.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS25822.1 - 2.8e-26 92.1 0.0 3.9e-25 88.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase SH3_1 PF00018.23 EPS25823.1 - 4.9e-06 25.8 0.0 9.3e-06 24.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EPS25823.1 - 0.00049 19.6 0.0 0.0009 18.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Rick_17kDa_Anti PF05433.10 EPS25824.1 - 1.3e-06 27.9 6.5 2.9e-06 26.8 4.5 1.5 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.1 EPS25824.1 - 0.0027 17.2 3.8 0.0051 16.4 2.6 1.4 1 0 0 1 1 1 1 Glycine zipper Gly-zipper_OmpA PF13436.1 EPS25824.1 - 0.033 13.8 0.2 0.061 12.9 0.1 1.5 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain PAT1 PF09770.4 EPS25824.1 - 0.94 7.6 3.7 1 7.5 2.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1183 PF06682.7 EPS25824.1 - 2.1 7.8 13.1 1.6 8.2 7.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) PQ-loop PF04193.9 EPS25825.1 - 2.6e-37 126.1 12.4 2.8e-18 65.2 3.9 2.4 2 0 0 2 2 2 2 PQ loop repeat V_ATPase_I PF01496.14 EPS25825.1 - 0.0049 14.7 0.1 0.0067 14.3 0.0 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family MtN3_slv PF03083.11 EPS25825.1 - 0.43 10.4 7.3 0.74 9.7 0.0 2.7 3 0 0 3 3 3 0 Sugar efflux transporter for intercellular exchange SKG6 PF08693.5 EPS25827.1 - 1.7e-05 23.9 0.4 3.3e-05 23.1 0.3 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Glycophorin_A PF01102.13 EPS25827.1 - 0.0043 16.8 0.1 0.0043 16.8 0.1 1.9 2 0 0 2 2 2 1 Glycophorin A Rax2 PF12768.2 EPS25827.1 - 0.0052 16.0 0.0 0.0066 15.6 0.0 1.2 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Lipoprotein_21 PF14041.1 EPS25827.1 - 0.82 9.6 5.0 2.3 8.1 0.0 3.4 2 1 1 3 3 3 0 LppP/LprE lipoprotein Aminotran_1_2 PF00155.16 EPS25829.1 - 3.2e-62 210.5 0.0 4e-62 210.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EPS25829.1 - 0.0025 16.9 0.0 0.0046 16.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.15 EPS25829.1 - 0.018 13.6 0.0 0.049 12.1 0.0 1.7 1 1 1 2 2 2 0 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.14 EPS25829.1 - 0.088 11.5 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V AMP-binding PF00501.23 EPS25830.1 - 1.3e-40 139.0 0.0 1.7e-40 138.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPS25830.1 - 8.4e-06 26.6 0.0 2.2e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CDT1 PF08839.6 EPS25830.1 - 0.086 12.7 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 DNA replication factor CDT1 like Peptidase_M16_C PF05193.16 EPS25831.1 - 8.9e-49 165.6 0.0 5.5e-48 163.0 0.0 2.3 3 1 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EPS25831.1 - 2.5e-41 140.9 0.0 8e-40 136.0 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Tom22 PF04281.8 EPS25832.1 - 5e-53 178.2 1.3 5.9e-53 178.0 0.9 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 DUF4211 PF13926.1 EPS25833.1 - 2.6e-38 130.8 1.0 7.7e-38 129.3 0.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4211) IncA PF04156.9 EPS25834.1 - 5.9 6.4 10.1 14 5.2 7.0 1.6 1 1 0 1 1 1 0 IncA protein Sugar_tr PF00083.19 EPS25835.1 - 4.6e-94 315.5 27.2 5.3e-94 315.3 18.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS25835.1 - 1.4e-29 102.9 31.3 1.2e-21 76.8 7.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EPS25835.1 - 0.0001 20.8 4.9 0.0001 20.8 3.4 3.5 2 2 1 3 3 3 2 MFS/sugar transport protein Topoisom_I_N PF02919.10 EPS25837.1 - 0.056 12.7 1.2 0.054 12.7 0.8 1.0 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment Telomere_Sde2 PF13019.1 EPS25837.1 - 0.11 12.2 0.9 0.11 12.1 0.6 1.0 1 0 0 1 1 1 0 Telomere stability and silencing FMO-like PF00743.14 EPS25838.1 - 1.7e-07 29.8 0.0 6.5e-05 21.3 0.0 2.8 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EPS25838.1 - 1.1e-05 25.6 0.0 2.4e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EPS25838.1 - 0.062 12.1 0.0 0.16 10.8 0.0 1.6 1 1 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EPS25838.1 - 0.087 12.6 0.0 0.66 9.8 0.0 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Zip PF02535.17 EPS25839.1 - 0.0045 16.0 2.9 0.0056 15.7 2.0 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter zf-UDP PF14569.1 EPS25839.1 - 0.016 14.9 2.3 0.029 14.0 1.6 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_5 PF14634.1 EPS25839.1 - 0.21 11.3 8.4 2.1 8.1 5.8 2.4 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EPS25839.1 - 0.33 10.8 6.2 0.21 11.5 2.0 2.1 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING SSFA2_C PF14723.1 EPS25839.1 - 0.34 10.6 5.2 0.062 13.0 1.1 1.6 2 0 0 2 2 2 0 Sperm-specific antigen 2 C-terminus zf-C3HC4 PF00097.20 EPS25839.1 - 0.4 10.3 7.7 2.6 7.7 5.3 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.11 EPS25839.1 - 0.94 9.3 5.5 0.14 12.0 0.2 2.0 2 0 0 2 2 2 0 FYVE-type zinc finger zf-C3HC4_2 PF13923.1 EPS25839.1 - 2 8.4 10.7 15 5.6 7.3 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) CPSF73-100_C PF11718.3 EPS25839.1 - 4.6 6.5 8.4 0.86 8.9 3.1 1.7 2 0 0 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term DUF3405 PF11885.3 EPS25840.1 - 2.7e-218 725.2 0.1 3.2e-218 724.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Arf PF00025.16 EPS25841.1 - 4.4e-79 263.7 0.1 5.1e-79 263.5 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EPS25841.1 - 5.2e-15 55.1 0.0 6.5e-15 54.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EPS25841.1 - 2.9e-13 49.5 0.0 3.3e-13 49.3 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EPS25841.1 - 3.6e-12 45.6 1.4 2.2e-09 36.4 0.2 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EPS25841.1 - 5.8e-11 41.9 0.0 6.8e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EPS25841.1 - 2e-08 34.7 0.0 2.8e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EPS25841.1 - 2.9e-06 27.2 0.0 3.9e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EPS25841.1 - 0.011 14.8 0.2 0.018 14.0 0.2 1.6 1 1 0 1 1 1 0 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 EPS25841.1 - 0.011 15.1 0.1 0.078 12.4 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 EPS25841.1 - 0.062 13.1 0.1 0.11 12.3 0.1 1.8 1 1 0 1 1 1 0 AAA domain CorA PF01544.13 EPS25842.1 - 1.7e-07 30.5 2.5 0.0036 16.3 0.4 3.3 2 1 1 3 3 3 3 CorA-like Mg2+ transporter protein VIT1 PF01988.14 EPS25842.1 - 0.031 13.7 1.2 0.06 12.8 0.4 1.8 2 0 0 2 2 2 0 VIT family Acetyltransf_1 PF00583.19 EPS25843.1 - 7.3e-12 45.1 0.1 1.2e-11 44.4 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EPS25843.1 - 7.1e-07 28.8 0.2 1.7e-06 27.6 0.1 1.6 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EPS25843.1 - 1e-05 25.6 0.0 2e-05 24.6 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPS25843.1 - 0.00017 21.6 0.2 0.00044 20.3 0.1 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EPS25843.1 - 0.00059 20.0 0.0 0.0015 18.6 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPS25843.1 - 0.0052 16.6 0.2 0.015 15.1 0.2 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EPS25843.1 - 0.0085 15.9 0.0 0.021 14.7 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Ribosomal_L1 PF00687.16 EPS25844.1 - 9.8e-52 175.4 0.5 1.2e-51 175.2 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family SNF PF00209.13 EPS25844.1 - 0.012 14.1 0.1 0.017 13.6 0.1 1.1 1 0 0 1 1 1 0 Sodium:neurotransmitter symporter family DEK_C PF08766.6 EPS25844.1 - 0.22 11.2 4.3 0.36 10.6 0.0 2.5 3 0 0 3 3 3 0 DEK C terminal domain RhoGEF PF00621.15 EPS25846.1 - 7.2e-38 130.2 0.0 1.7e-37 129.0 0.0 1.7 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.13 EPS25846.1 - 8.8e-11 41.7 0.9 2.1e-10 40.5 0.6 1.6 1 0 0 1 1 1 1 BAR domain Telomerase_RBD PF12009.3 EPS25847.1 - 5.1e-42 143.0 0.2 1.8e-41 141.2 0.1 2.0 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 EPS25847.1 - 1.9e-15 56.7 0.0 5.6e-15 55.2 0.0 1.7 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Parvo_coat PF00740.13 EPS25848.1 - 0.92 8.3 4.1 1.1 8.1 2.8 1.0 1 0 0 1 1 1 0 Parvovirus coat protein VP2 RabGAP-TBC PF00566.13 EPS25849.1 - 3.7e-27 95.1 0.0 5.7e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.20 EPS25850.1 - 8.4e-30 103.7 0.0 1.2e-23 83.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPS25850.1 - 3.3e-15 55.8 0.0 5.8e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ADH_zinc_N PF00107.21 EPS25851.1 - 7.6e-25 86.9 0.1 1.6e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPS25851.1 - 1.9e-08 35.2 0.0 4.5e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AMP-binding PF00501.23 EPS25853.1 - 5.3e-79 265.5 0.0 7.2e-79 265.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EPS25853.1 - 9.6e-34 116.5 0.0 1.7e-33 115.7 0.0 1.4 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.20 EPS25853.1 - 1.4e-09 38.0 0.0 4.3e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EPS25853.1 - 6.8e-08 33.3 0.9 5.6e-07 30.4 0.0 2.8 2 1 0 2 2 2 1 AMP-binding enzyme C-terminal domain Methyltransf_25 PF13649.1 EPS25854.1 - 7.9e-11 42.2 0.0 1.6e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPS25854.1 - 2.9e-08 34.0 0.0 5e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPS25854.1 - 3.8e-08 33.0 0.0 5.1e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPS25854.1 - 8.5e-08 32.5 0.0 1.6e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPS25854.1 - 1.3e-07 31.5 0.0 2.6e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS25854.1 - 2.6e-07 31.1 0.0 5.9e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPS25854.1 - 8e-07 29.1 0.0 1.5e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPS25854.1 - 0.0011 18.1 0.0 0.0016 17.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CheR PF01739.13 EPS25854.1 - 0.035 13.3 0.0 0.057 12.6 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_32 PF13679.1 EPS25854.1 - 0.037 13.7 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain SnoaL_3 PF13474.1 EPS25854.1 - 0.063 13.3 0.0 0.18 11.8 0.0 1.7 2 0 0 2 2 2 0 SnoaL-like domain Aminotran_5 PF00266.14 EPS25855.1 - 6.4e-19 67.9 0.0 9.9e-19 67.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EPS25855.1 - 0.01 14.1 0.0 0.016 13.4 0.0 1.3 1 1 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme PhyH PF05721.8 EPS25856.1 - 1e-17 64.9 0.2 1.4e-17 64.4 0.1 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) AMP-binding PF00501.23 EPS25857.1 - 2.8e-84 282.9 0.0 3.9e-84 282.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EPS25857.1 - 1.6e-15 56.7 0.1 1.4e-14 53.6 0.1 2.0 1 1 0 1 1 1 1 Condensation domain PP-binding PF00550.20 EPS25857.1 - 1e-09 38.5 0.1 6.9e-09 35.8 0.0 2.4 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EPS25857.1 - 0.00076 20.3 0.1 0.0046 17.8 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PhyH PF05721.8 EPS25858.1 - 9.5e-20 71.5 0.0 1.6e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 EPS25858.1 - 9.2e-05 21.0 0.0 0.00025 19.6 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1479) Transferase PF02458.10 EPS25859.1 - 1.2e-05 23.9 0.0 0.00074 18.0 0.0 2.3 2 0 0 2 2 2 2 Transferase family DUF4381 PF14316.1 EPS25859.1 - 0.068 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) NmrA PF05368.8 EPS25860.1 - 6.2e-29 100.9 0.0 8.2e-29 100.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPS25860.1 - 6.7e-05 22.9 0.0 0.0001 22.4 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EPS25860.1 - 0.027 13.4 0.0 0.039 12.9 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Trp_DMAT PF11991.3 EPS25861.1 - 5.3e-93 312.1 0.0 6.6e-93 311.7 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase DUF1769 PF08588.5 EPS25861.1 - 0.006 16.5 0.0 0.015 15.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) NmrA PF05368.8 EPS25862.1 - 1.2e-34 119.5 0.0 1.6e-34 119.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPS25862.1 - 1.7e-14 54.2 0.0 2.4e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EPS25862.1 - 3e-07 29.4 0.0 4.4e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EPS25862.1 - 8.6e-05 22.0 0.0 0.00014 21.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 EPS25862.1 - 0.0066 16.8 0.0 0.04 14.3 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Saccharop_dh PF03435.13 EPS25862.1 - 0.044 12.7 0.0 0.062 12.2 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase adh_short_C2 PF13561.1 EPS25863.1 - 9.8e-22 77.8 0.3 1.1e-21 77.7 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EPS25863.1 - 2e-12 47.3 0.4 2.8e-12 46.8 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EPS25863.1 - 1.2e-07 31.8 0.4 2.2e-06 27.7 0.1 2.1 1 1 1 2 2 2 2 NADH(P)-binding KR PF08659.5 EPS25863.1 - 0.00068 19.3 0.3 0.0011 18.7 0.2 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_7 PF13241.1 EPS25863.1 - 0.011 15.9 0.1 0.17 12.1 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding TrkA_N PF02254.13 EPS25863.1 - 0.026 14.5 0.1 0.12 12.4 0.0 2.2 3 0 0 3 3 3 0 TrkA-N domain Eno-Rase_NADH_b PF12242.3 EPS25863.1 - 0.051 13.3 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase FAD_binding_3 PF01494.14 EPS25864.1 - 1.3e-14 54.0 5.3 3.8e-13 49.2 3.7 2.6 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EPS25864.1 - 4.3e-08 32.4 2.1 0.00016 20.7 0.2 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPS25864.1 - 8.6e-06 24.8 0.7 2e-05 23.6 0.1 1.9 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.9 EPS25864.1 - 0.0053 16.6 0.0 0.017 15.0 0.0 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EPS25864.1 - 0.0054 15.2 0.4 0.019 13.4 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 EPS25864.1 - 0.0097 15.9 0.1 0.032 14.2 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EPS25864.1 - 0.046 12.6 0.3 6.3 5.6 0.1 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 EPS25864.1 - 0.068 12.7 0.2 0.14 11.6 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 EPS25864.1 - 0.1 11.4 0.2 0.13 11.1 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NmrA PF05368.8 EPS25865.1 - 9.9e-31 106.7 0.0 1.4e-30 106.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPS25865.1 - 1.8e-09 37.8 0.0 2.3e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EPS25865.1 - 0.011 14.4 0.0 0.038 12.7 0.0 1.8 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EPS25865.1 - 0.017 15.4 0.0 0.042 14.1 0.0 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 EPS25865.1 - 0.026 14.4 0.1 0.059 13.2 0.0 1.6 2 0 0 2 2 2 0 short chain dehydrogenase KR PF08659.5 EPS25865.1 - 0.048 13.3 0.0 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 KR domain Amino_oxidase PF01593.19 EPS25866.1 - 1.3e-32 113.4 0.1 9.5e-32 110.6 0.0 2.2 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EPS25866.1 - 2.2e-11 43.5 0.0 6.1e-11 42.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EPS25866.1 - 0.0011 18.8 0.0 0.0026 17.5 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.19 EPS25866.1 - 0.0074 15.2 0.1 0.017 14.0 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EPS25866.1 - 0.012 15.6 0.0 0.027 14.5 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPS25866.1 - 0.071 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family PhyH PF05721.8 EPS25867.1 - 5.1e-19 69.1 0.0 8e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 EPS25867.1 - 0.0016 17.0 0.0 0.003 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) NmrA PF05368.8 EPS25868.1 - 7.8e-29 100.5 0.0 1.1e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPS25868.1 - 1.4e-12 48.0 0.0 2.1e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EPS25868.1 - 0.00012 22.0 0.4 0.00025 21.0 0.3 1.5 2 0 0 2 2 2 1 short chain dehydrogenase TrkA_N PF02254.13 EPS25868.1 - 0.00015 21.7 0.0 0.00025 21.0 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.14 EPS25868.1 - 0.00031 19.5 0.0 0.00058 18.6 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 EPS25868.1 - 0.00099 18.8 0.2 0.0021 17.7 0.1 1.4 1 0 0 1 1 1 1 KR domain Semialdhyde_dh PF01118.19 EPS25868.1 - 0.0021 18.3 0.0 0.0085 16.3 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 EPS25868.1 - 0.0028 17.1 0.0 0.0049 16.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_25 PF13649.1 EPS25869.1 - 1.2e-09 38.4 0.1 2.1e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPS25869.1 - 1.3e-06 28.8 0.0 2.2e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPS25869.1 - 8.3e-06 25.8 1.0 1.5e-05 24.9 0.7 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS25869.1 - 1.4e-05 25.6 0.1 2.7e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPS25869.1 - 3.8e-05 23.3 0.0 5.5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPS25869.1 - 0.00028 21.3 0.0 0.00064 20.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPS25869.1 - 0.0012 18.5 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPS25869.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PhyH PF05721.8 EPS25870.1 - 4.6e-18 66.0 0.1 1.6e-17 64.2 0.0 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF3479 PF11965.3 EPS25870.1 - 0.004 16.9 0.0 0.0067 16.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3479) DUF1479 PF07350.7 EPS25870.1 - 0.0056 15.2 0.0 0.013 14.0 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1479) Trp_DMAT PF11991.3 EPS25871.1 - 2.6e-89 299.9 0.0 3.8e-89 299.4 0.0 1.2 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Arch_fla_DE PF04659.8 EPS25871.1 - 0.0018 18.0 0.0 0.0041 16.8 0.0 1.6 1 0 0 1 1 1 1 Archaeal flagella protein p450 PF00067.17 EPS25872.1 - 1.3e-68 231.6 0.0 1.5e-68 231.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.18 EPS25873.1 - 1.3e-18 66.7 3.3 3.6e-18 65.3 2.3 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EPS25873.1 - 2.4e-08 33.7 0.0 5e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like AMP-binding PF00501.23 EPS25874.1 - 3.3e-152 506.7 0.2 4.7e-76 255.8 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme NAD_binding_4 PF07993.7 EPS25874.1 - 1.5e-41 142.0 0.0 3.5e-41 140.7 0.0 1.7 1 0 0 1 1 1 1 Male sterility protein Condensation PF00668.15 EPS25874.1 - 2.7e-36 124.9 0.0 1.3e-35 122.7 0.0 2.2 2 1 0 2 2 2 1 Condensation domain PP-binding PF00550.20 EPS25874.1 - 1.4e-17 63.6 0.3 9.2e-08 32.2 0.1 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EPS25874.1 - 1.8e-08 35.2 0.0 0.0024 18.7 0.0 3.1 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Epimerase PF01370.16 EPS25874.1 - 1.2e-06 28.1 0.0 0.00047 19.6 0.0 2.5 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPS25874.1 - 0.00053 18.7 0.0 0.36 9.4 0.0 2.3 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EPS25874.1 - 0.0033 17.4 0.5 0.37 10.7 0.0 3.2 3 0 0 3 3 3 1 NADH(P)-binding GH3 PF03321.8 EPS25874.1 - 2 6.8 0.1 20 3.5 0.0 2.3 2 0 0 2 2 2 0 GH3 auxin-responsive promoter p450 PF00067.17 EPS25875.1 - 2.5e-43 148.2 0.0 3.1e-43 147.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 P5CR_dimer PF14748.1 EPS25876.1 - 7.8e-23 80.5 0.1 1e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation Glyco_tranf_2_3 PF13641.1 EPS25877.1 - 1.7e-11 44.3 1.7 2.4e-11 43.8 1.2 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EPS25877.1 - 5.4e-10 39.2 0.0 8.2e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EPS25877.1 - 0.0024 17.1 0.1 1.9 7.7 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 21 PipA PF07108.6 EPS25877.1 - 0.047 13.0 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 PipA protein MFS_1 PF07690.11 EPS25878.1 - 8.6e-33 113.5 27.7 8.6e-33 113.5 19.2 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily Abhydrolase_6 PF12697.2 EPS25879.1 - 7e-06 26.0 0.4 7e-06 26.0 0.3 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPS25879.1 - 0.00021 20.9 0.0 0.00052 19.6 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPS25879.1 - 0.037 13.7 0.1 0.62 9.8 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF676 PF05057.9 EPS25879.1 - 0.093 12.0 0.1 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.8 EPS25879.1 - 0.12 11.9 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_S9 PF00326.16 EPS25879.1 - 0.22 10.7 0.0 0.55 9.4 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family HisG PF01634.13 EPS25880.1 - 2.7e-50 170.1 1.0 4.2e-50 169.5 0.3 1.6 2 0 0 2 2 2 1 ATP phosphoribosyltransferase HisG_C PF08029.6 EPS25880.1 - 8.1e-27 92.9 0.3 1.8e-26 91.8 0.2 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.6 EPS25880.1 - 0.0089 15.6 0.1 0.014 15.0 0.1 1.3 1 0 0 1 1 1 1 NMT1/THI5 like Ribosomal_S28e PF01200.13 EPS25881.1 - 5.3e-34 115.7 2.2 5.8e-34 115.6 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e MutS_V PF00488.16 EPS25882.1 - 5.3e-89 297.6 0.0 9.1e-89 296.8 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EPS25882.1 - 4.7e-36 124.4 1.0 4.7e-36 124.4 0.7 1.7 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.15 EPS25882.1 - 3.9e-29 100.9 0.0 9.2e-29 99.7 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EPS25882.1 - 9e-09 35.5 0.0 3.3e-08 33.6 0.0 2.0 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EPS25882.1 - 8.8e-06 25.8 0.1 2.2e-05 24.5 0.1 1.7 1 0 0 1 1 1 1 MutS family domain IV zf-C2H2_2 PF12756.2 EPS25883.1 - 0.037 14.1 0.2 0.072 13.2 0.1 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Prenyltrans PF00432.16 EPS25884.1 - 3.2e-54 180.1 6.5 6.2e-11 41.6 0.0 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EPS25884.1 - 5.9e-30 103.9 0.1 9.4e-13 48.5 0.0 4.0 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EPS25884.1 - 5.4e-10 39.2 0.0 0.00024 21.0 0.0 3.5 2 1 0 2 2 2 2 Prenyltransferase-like RhoGAP PF00620.22 EPS25887.1 - 6.8e-30 103.6 0.0 1.3e-29 102.7 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain RRS1 PF04939.7 EPS25888.1 - 4.2e-58 195.4 2.2 4.9e-58 195.2 1.5 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) DAP3 PF10236.4 EPS25889.1 - 4.8e-98 327.9 0.0 6e-98 327.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 Fungal_trans PF04082.13 EPS25890.1 - 2.1e-20 72.7 0.0 3.1e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS25890.1 - 4.5e-07 29.6 10.7 8.4e-07 28.7 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidohydro_2 PF04909.9 EPS25891.1 - 3.3e-15 56.3 0.0 5.5e-15 55.6 0.0 1.4 2 0 0 2 2 2 1 Amidohydrolase AA_permease_2 PF13520.1 EPS25892.1 - 1.4e-46 158.9 51.0 3.3e-45 154.4 30.0 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease PF00324.16 EPS25892.1 - 3.4e-23 81.7 36.1 3.4e-23 81.7 25.1 1.6 2 0 0 2 2 2 1 Amino acid permease AA_permease PF00324.16 EPS25894.1 - 1.9e-128 428.8 40.9 2.4e-128 428.5 28.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPS25894.1 - 2.2e-35 122.0 44.9 2.9e-35 121.6 31.2 1.1 1 0 0 1 1 1 1 Amino acid permease HDOD PF08668.7 EPS25894.1 - 0.081 12.1 0.4 0.14 11.4 0.3 1.2 1 0 0 1 1 1 0 HDOD domain Glyoxalase_2 PF12681.2 EPS25895.1 - 1.6e-06 28.6 0.0 2.2e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain ADH_N PF08240.7 EPS25897.1 - 2.2e-25 88.5 0.4 4.4e-25 87.5 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPS25897.1 - 7.9e-25 86.8 0.4 1.1e-24 86.3 0.3 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MMtag PF10159.4 EPS25898.1 - 0.11 12.5 0.6 1.2 9.1 0.1 2.7 2 1 1 3 3 3 0 Kinase phosphorylation protein CDC45 PF02724.9 EPS25900.1 - 0.0016 16.5 0.6 0.0019 16.3 0.4 1.2 1 0 0 1 1 1 1 CDC45-like protein NOA36 PF06524.7 EPS25900.1 - 1.9 7.6 9.2 3.1 6.9 6.4 1.2 1 0 0 1 1 1 0 NOA36 protein Daxx PF03344.10 EPS25900.1 - 3.3 6.1 10.4 4.6 5.6 7.2 1.1 1 0 0 1 1 1 0 Daxx Family CobT PF06213.7 EPS25900.1 - 5 6.1 15.0 12 4.9 9.8 1.9 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT SET PF00856.23 EPS25903.1 - 5.9e-08 33.1 0.0 7.3e-07 29.6 0.0 2.7 2 0 0 2 2 2 1 SET domain TPR_11 PF13414.1 EPS25903.1 - 1.5e-06 27.7 0.0 3.3e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 TPR repeat SAP PF02037.22 EPS25903.1 - 7.4e-05 22.1 0.5 7.4e-05 22.1 0.4 2.5 3 0 0 3 3 3 1 SAP domain Aldo_ket_red PF00248.16 EPS25904.1 - 1.5e-65 220.8 0.0 1.7e-65 220.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Claudin_3 PF06653.6 EPS25904.1 - 0.045 13.4 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 Tight junction protein, Claudin-like Jacalin PF01419.12 EPS25904.1 - 0.052 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Jacalin-like lectin domain AAA_16 PF13191.1 EPS25905.1 - 3.5e-14 53.2 1.1 1.8e-13 50.9 0.1 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA PF00004.24 EPS25905.1 - 3e-12 46.8 0.0 1.3e-11 44.8 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPS25905.1 - 3.8e-12 46.4 0.1 1.3e-11 44.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain Cdc6_C PF09079.6 EPS25905.1 - 4.3e-06 26.3 0.0 1.4e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 CDC6, C terminal NTPase_1 PF03266.10 EPS25905.1 - 4.7e-06 26.4 0.0 1.1e-05 25.2 0.0 1.6 2 0 0 2 2 1 1 NTPase AAA_11 PF13086.1 EPS25905.1 - 0.0015 18.1 0.1 0.0027 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EPS25905.1 - 0.0019 17.9 0.0 0.0038 16.9 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_17 PF13207.1 EPS25905.1 - 0.0031 18.3 0.0 0.0066 17.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EPS25905.1 - 0.0031 17.6 0.0 0.0062 16.6 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AFG1_ATPase PF03969.11 EPS25905.1 - 0.0069 15.2 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 AFG1-like ATPase AAA_14 PF13173.1 EPS25905.1 - 0.0082 16.0 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EPS25905.1 - 0.0089 14.7 0.0 0.014 14.1 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus DUF815 PF05673.8 EPS25905.1 - 0.011 14.6 0.0 0.022 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PIF1 PF05970.9 EPS25905.1 - 0.019 13.9 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase T2SE PF00437.15 EPS25905.1 - 0.02 13.7 0.0 0.048 12.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.1 EPS25905.1 - 0.026 14.2 0.0 0.077 12.7 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 EPS25905.1 - 0.049 13.5 0.0 1.6 8.5 0.0 2.7 3 0 0 3 3 2 0 AAA domain DUF258 PF03193.11 EPS25905.1 - 0.057 12.6 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Rad17 PF03215.10 EPS25905.1 - 0.062 11.9 0.0 0.096 11.3 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Zeta_toxin PF06414.7 EPS25905.1 - 0.076 12.0 0.0 0.74 8.8 0.0 2.3 3 0 0 3 3 3 0 Zeta toxin AAA_18 PF13238.1 EPS25905.1 - 0.099 12.9 0.1 0.24 11.6 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_35 PF14516.1 EPS25905.1 - 0.15 10.6 0.0 0.97 8.0 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain DUF2075 PF09848.4 EPS25905.1 - 0.16 10.9 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Thioredoxin_7 PF13899.1 EPS25906.1 - 1.9e-15 56.5 0.1 7.9e-15 54.6 0.1 2.0 2 0 0 2 2 2 1 Thioredoxin-like UBA_4 PF14555.1 EPS25906.1 - 9.9e-14 50.5 0.1 2.3e-13 49.4 0.1 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 EPS25906.1 - 1.1e-08 35.0 0.0 5.8e-08 32.6 0.0 2.2 2 0 0 2 2 2 1 UBX domain Thioredox_DsbH PF03190.10 EPS25906.1 - 0.0017 18.1 0.1 0.0026 17.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_2 PF13098.1 EPS25906.1 - 0.017 15.2 0.1 0.051 13.7 0.1 1.9 1 1 0 1 1 1 0 Thioredoxin-like domain BDV_P24 PF06595.6 EPS25906.1 - 0.05 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Borna disease virus P24 protein Pkinase PF00069.20 EPS25907.1 - 2.7e-70 236.4 0.0 3.8e-70 236.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS25907.1 - 8e-51 172.5 0.0 1.3e-50 171.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPS25907.1 - 0.00019 20.4 0.0 0.00056 18.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like RhoGAP PF00620.22 EPS25908.1 - 1.3e-14 54.1 0.3 3.4e-14 52.7 0.2 1.7 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 EPS25908.1 - 4.7e-13 49.1 0.0 3.4e-12 46.3 0.0 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.16 EPS25908.1 - 4.8e-13 48.6 0.0 9.9e-13 47.6 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Phage_Gp14 PF10666.4 EPS25908.1 - 0.091 12.6 0.1 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 Phage protein Gp14 AA_permease PF00324.16 EPS25909.1 - 1e-143 479.1 41.7 1.2e-143 478.9 28.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPS25909.1 - 5.7e-36 123.9 41.2 7.7e-36 123.5 28.6 1.0 1 0 0 1 1 1 1 Amino acid permease LSM PF01423.17 EPS25912.1 - 7.9e-20 70.1 0.0 8.8e-20 70.0 0.0 1.0 1 0 0 1 1 1 1 LSM domain DNA_pol_A_exo1 PF01612.15 EPS25913.1 - 2.2e-17 63.0 0.0 4.1e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease Pex2_Pex12 PF04757.9 EPS25914.1 - 2e-42 145.1 8.2 2.5e-42 144.8 5.7 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 EPS25914.1 - 1e-10 41.4 8.8 1.6e-10 40.7 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPS25914.1 - 1.3e-10 40.7 6.5 2e-10 40.1 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPS25914.1 - 1.4e-10 40.6 6.5 2.2e-10 40.0 4.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPS25914.1 - 2.1e-10 40.2 9.6 3.3e-10 39.6 6.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EPS25914.1 - 1.3e-07 31.2 6.6 2.1e-07 30.5 4.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EPS25914.1 - 1.5e-05 24.7 7.8 2.6e-05 24.0 5.4 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EPS25914.1 - 1.9e-05 24.2 2.3 2.7e-05 23.7 0.4 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 EPS25914.1 - 0.00014 21.8 8.0 0.00039 20.4 5.6 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 EPS25914.1 - 0.0017 18.1 3.7 0.0033 17.1 2.6 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EPS25914.1 - 0.051 13.4 3.5 0.09 12.6 2.3 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EPS25914.1 - 0.081 12.5 7.4 0.15 11.6 5.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 EPS25914.1 - 0.1 12.1 3.4 0.22 11.0 2.4 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FYVE PF01363.16 EPS25914.1 - 0.27 11.1 6.5 0.94 9.4 4.5 1.9 1 1 0 1 1 1 0 FYVE zinc finger IBR PF01485.16 EPS25914.1 - 1.3 8.9 7.6 4.4 7.2 5.3 1.9 1 1 0 1 1 1 0 IBR domain EXS PF03124.9 EPS25915.1 - 4.7e-95 318.5 15.9 5.4e-95 318.3 11.0 1.0 1 0 0 1 1 1 1 EXS family UCH_1 PF13423.1 EPS25915.1 - 0.17 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase DUF1510 PF07423.6 EPS25916.1 - 0.0024 17.2 1.9 0.0039 16.5 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) MIP-T3 PF10243.4 EPS25916.1 - 0.076 11.4 5.9 0.093 11.1 4.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 KAR9 PF08580.5 EPS25916.1 - 0.22 9.7 15.7 0.3 9.3 10.9 1.3 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Apt1 PF10351.4 EPS25916.1 - 0.25 10.1 9.0 0.36 9.6 6.2 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain Menin PF05053.8 EPS25916.1 - 4 5.5 9.4 7.6 4.5 6.5 1.4 1 0 0 1 1 1 0 Menin ATP-synt_S1 PF05827.7 EPS25917.1 - 1.4e-62 211.5 0.0 1.6e-62 211.3 0.0 1.0 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Nop25 PF09805.4 EPS25918.1 - 5.3e-39 133.4 16.7 5.3e-39 133.4 11.6 2.7 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) DUF4522 PF15022.1 EPS25918.1 - 0.33 10.6 6.1 0.039 13.6 0.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4522) Tropomyosin_1 PF12718.2 EPS25919.1 - 5.2e-49 165.7 39.6 6e-49 165.5 27.5 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 EPS25919.1 - 2.4e-10 39.9 36.6 8.2e-05 21.7 14.3 2.8 1 1 1 2 2 2 2 Tropomyosin Mod_r PF07200.8 EPS25919.1 - 0.00029 20.7 27.9 0.075 12.9 13.7 2.1 1 1 1 2 2 2 2 Modifier of rudimentary (Mod(r)) protein ADIP PF11559.3 EPS25919.1 - 0.00073 19.4 34.2 0.038 13.8 11.8 2.8 1 1 2 3 3 3 2 Afadin- and alpha -actinin-Binding Laminin_II PF06009.7 EPS25919.1 - 0.0025 17.5 20.9 0.007 16.1 5.5 2.1 1 1 1 2 2 2 2 Laminin Domain II ATG16 PF08614.6 EPS25919.1 - 0.0031 17.3 32.1 0.043 13.6 7.8 2.5 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) DUF4200 PF13863.1 EPS25919.1 - 0.0046 16.9 17.3 0.0046 16.9 12.0 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF4200) TBPIP PF07106.8 EPS25919.1 - 0.0083 15.6 29.6 0.17 11.4 10.3 3.0 1 1 2 3 3 3 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) GAS PF13851.1 EPS25919.1 - 0.011 14.9 32.5 0.041 13.0 16.2 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 EPS25919.1 - 0.015 14.8 35.3 18 4.8 24.5 2.3 1 1 0 1 1 1 0 IncA protein MAD PF05557.8 EPS25919.1 - 0.021 12.9 26.2 0.058 11.4 18.2 1.7 1 1 0 1 1 1 0 Mitotic checkpoint protein Atg14 PF10186.4 EPS25919.1 - 0.028 13.3 30.5 0.016 14.1 15.6 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 KLRAQ PF10205.4 EPS25919.1 - 0.04 13.9 24.9 0.029 14.3 9.2 2.8 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein APG6 PF04111.7 EPS25919.1 - 0.065 12.2 36.5 0.55 9.2 12.1 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 NABP PF07990.7 EPS25919.1 - 0.083 12.1 5.6 0.091 12.0 3.9 1.2 1 0 0 1 1 1 0 Nucleic acid binding protein NABP Cast PF10174.4 EPS25919.1 - 0.1 10.6 32.8 0.13 10.2 22.7 1.2 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone DUF4201 PF13870.1 EPS25919.1 - 0.13 11.7 30.3 0.4 10.1 20.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Reo_sigmaC PF04582.7 EPS25919.1 - 0.13 11.4 7.7 0.27 10.3 4.3 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein TMF_TATA_bd PF12325.3 EPS25919.1 - 0.13 11.9 31.2 1.3 8.7 12.9 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Fmp27_WPPW PF10359.4 EPS25919.1 - 0.13 10.6 28.0 0.18 10.2 8.5 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Spc7 PF08317.6 EPS25919.1 - 0.16 10.6 29.5 0.054 12.1 12.2 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Syntaxin-6_N PF09177.6 EPS25919.1 - 0.17 12.3 21.4 1.3 9.5 3.3 3.2 1 1 2 3 3 3 0 Syntaxin 6, N-terminal TMF_DNA_bd PF12329.3 EPS25919.1 - 0.17 11.6 38.7 65 3.4 17.1 4.0 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding bZIP_1 PF00170.16 EPS25919.1 - 0.2 11.6 32.2 0.42 10.6 0.9 4.5 1 1 4 5 5 5 0 bZIP transcription factor Fez1 PF06818.10 EPS25919.1 - 0.22 11.5 30.4 0.25 11.3 21.1 1.0 1 0 0 1 1 1 0 Fez1 FlaC_arch PF05377.6 EPS25919.1 - 0.26 11.2 23.1 0.097 12.5 2.4 4.3 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) SPX PF03105.14 EPS25919.1 - 0.28 10.9 18.0 0.42 10.3 12.5 1.4 1 0 0 1 1 1 0 SPX domain BLOC1_2 PF10046.4 EPS25919.1 - 0.32 11.1 21.9 15 5.8 4.9 3.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LPP PF04728.8 EPS25919.1 - 0.33 10.7 5.3 0.35 10.6 1.1 2.7 2 1 1 3 3 3 0 Lipoprotein leucine-zipper RdRP_4 PF02123.11 EPS25919.1 - 0.37 9.4 9.8 0.43 9.2 6.8 1.0 1 0 0 1 1 1 0 Viral RNA-directed RNA-polymerase DUF904 PF06005.7 EPS25919.1 - 0.44 10.8 40.4 3.4 8.0 7.3 3.3 1 1 2 3 3 3 0 Protein of unknown function (DUF904) DUF3450 PF11932.3 EPS25919.1 - 0.46 9.7 27.6 1.5 8.0 3.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF4618 PF15397.1 EPS25919.1 - 0.48 9.7 26.8 1.5 8.1 8.2 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4618) Striatin PF08232.7 EPS25919.1 - 0.53 10.5 29.6 3.6 7.8 1.7 2.8 1 1 2 3 3 3 0 Striatin family TPR_MLP1_2 PF07926.7 EPS25919.1 - 0.57 9.9 37.8 0.4 10.4 8.6 2.2 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein CCDC155 PF14662.1 EPS25919.1 - 0.6 9.6 35.9 5.8 6.4 9.7 2.8 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 Fib_alpha PF08702.5 EPS25919.1 - 0.7 10.0 19.8 3.4 7.7 5.3 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.14 EPS25919.1 - 0.71 7.6 21.4 1.2 6.9 14.8 1.4 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 EPS25919.1 - 0.73 10.2 29.2 0.34 11.2 9.5 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF972) AAA_13 PF13166.1 EPS25919.1 - 1.1 7.6 27.5 0.72 8.2 13.3 2.0 1 1 1 2 2 2 0 AAA domain MS_channel PF00924.13 EPS25919.1 - 1.1 8.5 2.9 0.76 9.0 1.1 1.5 1 1 1 2 2 2 0 Mechanosensitive ion channel ERM PF00769.14 EPS25919.1 - 1.1 8.7 39.9 1.2 8.6 12.0 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF3287 PF11690.3 EPS25919.1 - 1.3 9.1 14.1 0.17 11.9 1.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3287) YbaB_DNA_bd PF02575.11 EPS25919.1 - 1.6 8.7 17.2 6.2 6.7 6.2 3.6 2 1 0 3 3 3 0 YbaB/EbfC DNA-binding family DUF2721 PF11026.3 EPS25919.1 - 1.8 8.2 5.4 13 5.3 0.4 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) FUSC PF04632.7 EPS25919.1 - 2.1 6.6 10.8 2.7 6.3 7.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family TMP_2 PF06791.8 EPS25919.1 - 2.4 7.7 6.1 10 5.6 0.9 2.1 1 1 1 2 2 2 0 Prophage tail length tape measure protein PspA_IM30 PF04012.7 EPS25919.1 - 2.5 7.3 34.6 0.36 10.1 4.2 2.1 1 1 1 2 2 2 0 PspA/IM30 family SlyX PF04102.7 EPS25919.1 - 2.5 8.5 25.1 4.7 7.6 1.1 4.0 1 1 4 5 5 5 0 SlyX NPV_P10 PF05531.7 EPS25919.1 - 2.7 8.3 14.2 47 4.3 0.1 3.4 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Nup54 PF13874.1 EPS25919.1 - 2.7 7.6 29.5 1.9e+02 1.6 13.6 3.5 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Rab5-bind PF09311.6 EPS25919.1 - 2.9 7.7 35.7 5 6.9 24.7 1.4 1 1 0 1 1 1 0 Rabaptin-like protein HAP1_N PF04849.8 EPS25919.1 - 3 6.7 33.8 1.6e+02 1.0 23.4 3.1 1 1 0 1 1 1 0 HAP1 N-terminal conserved region IFT46_B_C PF12317.3 EPS25919.1 - 3.5 6.9 12.3 0.31 10.3 3.5 2.0 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal HSP70 PF00012.15 EPS25919.1 - 3.6 5.3 20.3 4.7 4.9 14.0 1.2 1 0 0 1 1 1 0 Hsp70 protein DivIVA PF05103.8 EPS25919.1 - 3.8 7.5 32.6 9 6.3 2.3 3.3 1 1 2 3 3 3 0 DivIVA protein Uds1 PF15456.1 EPS25919.1 - 3.9 7.5 28.1 3.2 7.7 12.7 2.3 1 1 1 2 2 2 0 Up-regulated During Septation CENP-F_leu_zip PF10473.4 EPS25919.1 - 4.1 7.2 35.6 0.93 9.3 4.3 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3584 PF12128.3 EPS25919.1 - 4.5 4.4 33.1 11 3.2 23.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Lebercilin PF15619.1 EPS25919.1 - 5.3 6.4 36.9 5.3 6.4 11.9 2.1 1 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Seryl_tRNA_N PF02403.17 EPS25919.1 - 7 6.7 30.1 3.4 7.7 2.8 3.2 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Phage_GP20 PF06810.6 EPS25919.1 - 7.4 5.9 30.1 3.6 7.0 12.6 2.7 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF1664 PF07889.7 EPS25919.1 - 7.9 6.2 16.0 5.8 6.7 0.3 3.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF812 PF05667.6 EPS25919.1 - 9 4.6 30.1 12 4.2 20.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Allexi_40kDa PF05549.6 EPS25919.1 - 9.4 5.4 15.5 2 7.6 5.8 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF4551 PF15087.1 EPS25920.1 - 0.16 10.2 3.8 0.24 9.7 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CMAS PF02353.15 EPS25921.1 - 1.8e-61 207.6 0.1 2.3e-61 207.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EPS25921.1 - 3e-10 40.0 0.0 5.4e-10 39.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPS25921.1 - 1e-06 29.1 0.0 1.9e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS25921.1 - 0.00038 21.0 0.0 0.00077 20.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPS25921.1 - 0.0014 18.9 0.1 0.0047 17.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPS25921.1 - 0.0018 18.7 0.0 0.0036 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPS25921.1 - 0.0025 17.8 0.0 0.0076 16.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPS25921.1 - 0.003 16.9 0.0 0.0048 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DOT1 PF08123.8 EPS25921.1 - 0.0032 16.8 0.0 0.006 15.9 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_31 PF13847.1 EPS25921.1 - 0.0083 15.7 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EPS25921.1 - 0.032 13.7 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Fungal_trans_2 PF11951.3 EPS25922.1 - 5.2e-46 156.9 0.3 8.3e-46 156.3 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS25922.1 - 0.0044 16.8 6.5 0.01 15.7 4.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pex24p PF06398.6 EPS25923.1 - 2.8e-100 335.6 2.8 4.3e-100 335.0 1.9 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin JSRP PF15312.1 EPS25923.1 - 0.11 12.4 0.1 0.29 11.1 0.0 1.8 1 0 0 1 1 1 0 Junctional sarcoplasmic reticulum protein Pam16 PF03656.8 EPS25924.1 - 4.3e-34 117.0 0.4 5.5e-34 116.6 0.3 1.1 1 0 0 1 1 1 1 Pam16 Aldo_ket_red PF00248.16 EPS25925.1 - 4.4e-65 219.3 0.0 6.3e-65 218.8 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family PAP_assoc PF03828.14 EPS25926.1 - 5.7e-12 45.4 0.3 1.1e-11 44.5 0.2 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EPS25926.1 - 8.6e-10 38.8 0.0 1.7e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain PRKCSH-like PF12999.2 EPS25928.1 - 3.1e-46 157.1 9.3 1.7e-27 96.1 0.3 3.0 4 0 0 4 4 4 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 EPS25928.1 - 8.2e-32 109.7 4.1 8.9e-32 109.6 1.1 2.2 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 EPS25928.1 - 7.3e-10 39.5 0.7 2.3e-09 37.8 0.5 1.9 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Fib_alpha PF08702.5 EPS25928.1 - 0.003 17.6 4.4 0.95 9.5 0.3 3.2 3 0 0 3 3 3 1 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.14 EPS25928.1 - 0.13 10.0 3.5 0.11 10.2 1.3 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family TBCA PF02970.11 EPS25928.1 - 0.3 11.2 0.1 0.3 11.2 0.1 2.9 2 1 1 3 3 3 0 Tubulin binding cofactor A FTA4 PF13093.1 EPS25928.1 - 0.39 10.1 3.8 0.14 11.5 0.7 1.6 2 0 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 NPV_P10 PF05531.7 EPS25928.1 - 0.57 10.4 3.4 26 5.1 0.1 3.3 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF4407 PF14362.1 EPS25928.1 - 0.78 8.6 12.0 0.75 8.6 6.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Snapin_Pallidin PF14712.1 EPS25928.1 - 0.93 9.8 0.0 0.93 9.8 0.0 2.8 3 0 0 3 3 3 0 Snapin/Pallidin SlyX PF04102.7 EPS25928.1 - 2 8.8 7.7 19 5.7 0.1 3.7 3 1 0 3 3 3 0 SlyX PRCC PF10253.4 EPS25928.1 - 2.2 8.9 7.2 1.1 9.8 3.2 1.8 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting IncA PF04156.9 EPS25928.1 - 4.5 6.8 11.2 3.8 7.0 5.2 2.3 2 1 0 2 2 2 0 IncA protein Rtf2 PF04641.7 EPS25929.1 - 6.4e-71 238.5 1.4 7.2e-71 238.4 1.0 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 EPS25929.1 - 8.5e-09 34.7 0.0 0.0059 16.1 0.0 2.8 2 1 1 3 3 3 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EPS25929.1 - 2.2e-05 24.0 0.3 5.5e-05 22.8 0.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 EPS25929.1 - 0.0016 18.1 0.1 0.0034 17.0 0.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EPS25929.1 - 0.0058 16.4 0.3 0.038 13.8 0.0 2.4 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.1 EPS25929.1 - 0.044 13.4 0.1 0.093 12.4 0.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPS25929.1 - 0.092 12.7 0.0 0.33 10.9 0.0 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Plasmodium_Vir PF05795.6 EPS25929.1 - 0.13 11.4 3.0 0.23 10.5 2.1 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Ribosomal_L50 PF10501.4 EPS25930.1 - 6.7e-12 45.3 0.1 1.1e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal subunit 39S Thiolase_N PF00108.18 EPS25931.1 - 7.7e-79 264.3 0.4 1.2e-78 263.7 0.3 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EPS25931.1 - 2e-45 153.1 1.3 3.6e-45 152.3 0.6 1.6 2 0 0 2 2 2 1 Thiolase, C-terminal domain Oxidored_molyb PF00174.14 EPS25932.1 - 8.9e-33 113.0 0.0 1.7e-32 112.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EPS25932.1 - 2e-24 85.6 0.1 3.6e-24 84.8 0.1 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain zf-RING_2 PF13639.1 EPS25933.1 - 4.4e-12 45.6 5.6 8.5e-12 44.7 3.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EPS25933.1 - 3.8e-07 30.0 3.7 3.8e-07 30.0 2.6 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPS25933.1 - 2.2e-06 27.2 1.8 4.1e-06 26.4 1.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EPS25933.1 - 5.4e-06 25.9 2.1 1.1e-05 24.9 1.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EPS25933.1 - 6.4e-06 26.1 4.4 1.2e-05 25.3 3.0 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EPS25933.1 - 1.8e-05 24.3 1.9 3.3e-05 23.4 1.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EPS25933.1 - 4.9e-05 23.0 3.4 6.8e-05 22.6 2.4 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EPS25933.1 - 0.027 14.0 3.2 0.027 14.0 2.2 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 EPS25933.1 - 0.029 14.3 0.7 0.029 14.3 0.5 2.0 2 1 0 2 2 2 0 RING-variant domain PHD PF00628.24 EPS25933.1 - 0.19 11.4 4.2 0.084 12.5 1.1 1.9 2 0 0 2 2 2 0 PHD-finger Prok-RING_4 PF14447.1 EPS25933.1 - 0.4 10.2 3.2 0.91 9.1 2.2 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Vps39_2 PF10367.4 EPS25933.1 - 0.46 10.6 2.1 0.81 9.8 0.3 2.0 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-RING-like PF08746.6 EPS25933.1 - 0.68 9.9 5.3 3 7.9 3.7 2.2 1 1 0 1 1 1 0 RING-like domain zf-H2C2_2 PF13465.1 EPS25933.1 - 2.8 8.3 5.2 1.4 9.3 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger double domain RNase_H PF00075.19 EPS25934.1 - 2.4e-10 40.8 0.0 4.2e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EPS25934.1 - 0.03 14.1 0.4 3.3 7.5 0.1 3.0 2 1 0 2 2 2 0 Reverse transcriptase-like RNase_H PF00075.19 EPS25935.1 - 1.6e-11 44.6 0.0 2.4e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EPS25935.1 - 4.4e-05 23.1 0.0 0.0027 17.4 0.0 3.0 3 0 0 3 3 3 1 Reverse transcriptase-like DAHP_synth_1 PF00793.15 EPS25937.1 - 1.1e-93 312.8 0.0 1.4e-93 312.5 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family COX14 PF14880.1 EPS25938.1 - 1.4e-18 66.2 0.2 1.4e-18 66.2 0.2 2.2 2 0 0 2 2 2 1 Cytochrome oxidase c assembly ECM11 PF15463.1 EPS25938.1 - 0.0032 17.7 0.0 0.0032 17.7 0.0 2.3 2 1 0 2 2 2 1 Extracellular mutant protein 11 Phosphoprotein PF00922.12 EPS25938.1 - 0.032 13.4 0.3 0.058 12.6 0.2 1.4 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein TFIIA PF03153.8 EPS25938.1 - 0.72 9.6 6.8 1.4 8.7 4.7 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2458 PF10454.4 EPS25939.1 - 1.1e-43 148.6 0.2 1.7e-43 148.0 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) DUF1331 PF07048.6 EPS25939.1 - 0.059 12.8 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) NLPC_P60 PF00877.14 EPS25940.1 - 1.4e-18 66.6 0.0 2.2e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 NlpC/P60 family Amidase_5 PF05382.8 EPS25940.1 - 0.00048 19.7 0.8 0.00073 19.1 0.2 1.7 1 1 0 1 1 1 1 Bacteriophage peptidoglycan hydrolase SH3_3 PF08239.6 EPS25940.1 - 0.0035 17.4 0.2 0.0079 16.3 0.1 1.6 1 1 0 1 1 1 1 Bacterial SH3 domain DUF1175 PF06672.6 EPS25940.1 - 0.051 12.9 0.0 8.2 5.7 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1175) Serglycin PF04360.7 EPS25940.1 - 0.69 9.6 10.6 1.7 8.3 7.3 1.8 1 1 0 1 1 1 0 Serglycin F-box PF00646.28 EPS25941.1 - 2.5e-06 26.9 0.1 7.9e-06 25.3 0.1 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EPS25941.1 - 6.1e-05 22.6 0.5 0.00019 21.0 0.1 2.0 2 0 0 2 2 2 1 F-box-like DYW_deaminase PF14432.1 EPS25941.1 - 0.12 12.3 0.2 0.28 11.1 0.1 1.6 1 0 0 1 1 1 0 DYW family of nucleic acid deaminases Hexokinase_2 PF03727.11 EPS25942.1 - 3.9e-35 121.2 0.0 4.8e-27 94.7 0.0 2.2 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 EPS25942.1 - 4e-33 114.4 0.0 5.8e-33 113.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Arylsulfotran_2 PF14269.1 EPS25943.1 - 4.2e-44 150.9 1.4 7.2e-44 150.1 1.0 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EPS25943.1 - 1.6e-16 59.9 1.6 5.1e-15 54.9 1.2 2.1 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) COesterase PF00135.23 EPS25944.1 - 1.3e-86 291.4 0.6 1.9e-86 290.9 0.4 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EPS25944.1 - 1.6e-06 27.8 0.0 4e-06 26.5 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EPS25944.1 - 0.00039 19.6 0.3 0.00078 18.7 0.2 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EPS25944.1 - 0.0036 17.0 0.1 0.0098 15.6 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.5 EPS25944.1 - 0.087 11.6 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Sugar_tr PF00083.19 EPS25945.1 - 1e-106 357.2 24.9 1.2e-106 356.9 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS25945.1 - 1.8e-17 63.0 39.9 3.8e-12 45.5 7.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ribosomal_L12 PF00542.14 EPS25945.1 - 0.024 14.6 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L7/L12 C-terminal domain ADK PF00406.17 EPS25948.1 - 6.8e-44 149.3 0.0 9.2e-44 148.9 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EPS25948.1 - 3.1e-08 34.0 0.0 4.7e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPS25948.1 - 4.8e-08 33.8 0.0 7.2e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EPS25948.1 - 2.2e-07 30.8 0.1 5.4e-06 26.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EPS25948.1 - 8.1e-07 28.5 0.0 0.011 15.1 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase SRP54 PF00448.17 EPS25948.1 - 0.047 13.1 0.0 0.087 12.2 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PCI PF01399.22 EPS25949.1 - 6.4e-13 48.9 0.0 1.7e-12 47.5 0.0 1.8 2 0 0 2 2 2 1 PCI domain Macoilin PF09726.4 EPS25950.1 - 1.2 7.2 8.4 1.4 7.0 5.8 1.1 1 0 0 1 1 1 0 Transmembrane protein DNA_pol_viral_N PF00242.12 EPS25950.1 - 2.7 6.9 6.6 3.5 6.5 4.6 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Rifin_STEVOR PF02009.11 EPS25950.1 - 4.5 6.8 5.4 5.2 6.6 3.8 1.1 1 0 0 1 1 1 0 Rifin/stevor family Med3 PF11593.3 EPS25950.1 - 5.3 6.1 13.7 7.2 5.7 9.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal 4HBT PF03061.17 EPS25952.1 - 1.9e-08 34.2 0.1 3.3e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EPS25953.1 - 1.3e-62 211.8 6.1 1.5e-62 211.6 4.2 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4452 PF14618.1 EPS25954.1 - 0.53 10.0 12.6 1.1 9.0 8.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4452) Glyco_transf_20 PF00982.16 EPS25955.1 - 1.7e-160 534.6 0.0 2.4e-160 534.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EPS25955.1 - 5.1e-40 136.8 0.0 8e-40 136.2 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_5 PF08323.6 EPS25955.1 - 0.1 12.0 0.2 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 Starch synthase catalytic domain DUF3979 PF13141.1 EPS25955.1 - 0.15 11.9 0.0 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3979) TFIID_90kDa PF04494.10 EPS25955.1 - 0.17 11.9 0.2 0.46 10.5 0.1 1.7 2 0 0 2 2 2 0 WD40 associated region in TFIID subunit Stk19 PF10494.4 EPS25956.1 - 1.1e-78 264.1 0.0 1.3e-78 263.8 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 DUF3074 PF11274.3 EPS25957.1 - 1.4e-09 37.8 0.1 2.1e-09 37.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) Claudin_3 PF06653.6 EPS25958.1 - 0.039 13.6 0.9 1.6 8.4 0.1 2.3 2 0 0 2 2 2 0 Tight junction protein, Claudin-like zf-H2C2_2 PF13465.1 EPS25959.1 - 5.1e-15 54.9 18.3 6.5e-09 35.6 2.0 3.8 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EPS25959.1 - 1.2e-11 44.1 21.7 0.0009 19.4 3.1 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPS25959.1 - 8.7e-08 31.9 22.2 0.0035 17.5 3.1 4.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EPS25959.1 - 0.00034 20.6 8.1 0.14 12.3 1.1 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EPS25959.1 - 0.0062 16.4 13.6 0.013 15.4 0.1 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-CHCC PF10276.4 EPS25959.1 - 0.0091 15.8 4.3 3.4 7.6 0.0 3.8 4 0 0 4 4 4 1 Zinc-finger domain zf-Di19 PF05605.7 EPS25959.1 - 0.022 14.9 9.6 0.047 13.8 3.8 2.5 1 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding RRN7 PF11781.3 EPS25959.1 - 0.067 12.7 0.3 8.3 6.0 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Zn-ribbon_8 PF09723.5 EPS25959.1 - 0.18 11.8 10.1 2 8.4 2.7 3.1 1 1 2 3 3 3 0 Zinc ribbon domain zf-RING_3 PF14369.1 EPS25959.1 - 0.19 11.7 5.2 15 5.7 0.1 3.4 3 0 0 3 3 3 0 zinc-finger zf-CHY PF05495.7 EPS25959.1 - 0.31 11.2 5.9 0.61 10.2 4.1 1.4 1 0 0 1 1 1 0 CHY zinc finger DZR PF12773.2 EPS25959.1 - 0.42 10.4 7.8 6.4 6.6 5.4 2.3 1 1 1 2 2 2 0 Double zinc ribbon zf-C3HC4_3 PF13920.1 EPS25959.1 - 0.52 10.0 5.1 1.9 8.2 0.5 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C2HC_2 PF13913.1 EPS25959.1 - 0.64 9.7 8.6 0.032 13.8 1.2 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zinc-ribbons_6 PF07191.7 EPS25959.1 - 1.2 9.0 4.4 2 8.2 1.5 2.1 2 0 0 2 2 2 0 zinc-ribbons zf-C2H2_2 PF12756.2 EPS25959.1 - 1.7 8.8 10.7 1.6 8.8 0.8 3.2 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) FYVE PF01363.16 EPS25959.1 - 2.7 7.9 11.1 1.6 8.6 2.4 2.4 1 1 1 2 2 2 0 FYVE zinc finger FYDLN_acid PF09538.5 EPS25959.1 - 3.1 8.4 10.5 1.6 9.3 0.9 3.4 2 1 1 3 3 3 0 Protein of unknown function (FYDLN_acid) HypA PF01155.14 EPS25959.1 - 3.3 7.4 4.6 4.2 7.0 2.1 1.8 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-ISL3 PF14690.1 EPS25959.1 - 4 7.5 10.6 1.8 8.6 0.3 3.2 3 0 0 3 3 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 GAGA PF09237.6 EPS25959.1 - 7.9 6.1 13.8 2.6 7.7 0.9 3.5 1 1 2 3 3 3 0 GAGA factor MARVEL PF01284.18 EPS25961.1 - 0.00075 19.3 8.7 0.0013 18.5 2.5 2.4 2 0 0 2 2 2 1 Membrane-associating domain Tetraspannin PF00335.15 EPS25961.1 - 0.0017 17.7 4.4 0.0017 17.7 3.1 1.5 1 1 0 1 1 1 1 Tetraspanin family DUF202 PF02656.10 EPS25961.1 - 0.16 12.2 6.2 2.8 8.2 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF202) FixQ PF05545.6 EPS25961.1 - 0.2 11.2 5.0 1.6 8.4 0.3 2.8 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF373 PF04123.8 EPS25961.1 - 0.29 10.1 1.3 0.32 9.9 0.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF373) DUF4131 PF13567.1 EPS25961.1 - 3.1 7.1 7.1 1.8 7.9 3.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Cnd2 PF05786.9 EPS25962.1 - 4.8e-253 841.9 3.6 5.7e-253 841.7 2.5 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 Na_Ca_ex PF01699.19 EPS25963.1 - 1.8e-45 153.9 39.0 1.6e-24 86.0 9.0 3.3 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Herpes_gE PF02480.11 EPS25963.1 - 0.22 9.7 0.0 0.84 7.8 0.0 2.0 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Sugar_tr PF00083.19 EPS25964.1 - 4.7e-91 305.6 32.7 5.3e-91 305.4 22.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS25964.1 - 1.1e-23 83.5 39.2 1.8e-23 82.8 25.4 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPS25964.1 - 0.00079 17.7 4.3 0.00079 17.7 3.0 2.0 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EPS25964.1 - 0.0051 15.2 28.0 0.018 13.4 8.4 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein EF-hand_4 PF12763.2 EPS25965.1 - 1.4e-24 85.8 0.0 7.4e-11 41.7 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF1720 PF08226.6 EPS25965.1 - 1e-14 54.3 151.1 5.1e-06 26.4 16.6 7.5 5 1 2 7 7 7 6 Domain of unknown function (DUF1720) WH2 PF02205.15 EPS25965.1 - 6.7e-11 41.4 0.5 1.4e-10 40.3 0.4 1.6 1 0 0 1 1 1 1 WH2 motif EF-hand_7 PF13499.1 EPS25965.1 - 3.4e-06 27.0 0.2 4.9e-05 23.3 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EPS25965.1 - 0.0036 16.5 0.1 2.5 7.6 0.0 3.2 4 0 0 4 4 4 2 EF hand RNA_pol_L_2 PF13656.1 EPS25966.1 - 6e-24 83.2 0.0 8.7e-24 82.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EPS25966.1 - 2.8e-14 51.9 0.0 4.3e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain PBP1_TM PF14812.1 EPS25967.1 - 0.14 12.4 13.9 3.4 8.0 4.6 2.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleo_P87 PF07267.6 EPS25967.1 - 2.9 6.4 9.8 0.99 8.0 3.9 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 PMT PF02366.13 EPS25969.1 - 6.3e-83 277.8 20.1 1.2e-82 276.9 14.0 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EPS25969.1 - 1.1e-17 64.2 0.1 8.2e-17 61.3 0.0 2.0 1 1 1 2 2 2 1 MIR domain PMT_2 PF13231.1 EPS25969.1 - 0.00044 20.1 13.2 0.00044 20.1 9.1 3.3 4 0 0 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase NAD_binding_4 PF07993.7 EPS25970.1 - 0.0018 17.2 0.0 0.0043 16.0 0.0 1.7 1 0 0 1 1 1 1 Male sterility protein Methyltransf_3 PF01596.12 EPS25972.1 - 1.8e-14 53.2 0.0 2.3e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EPS25972.1 - 1.9e-11 44.7 0.0 3e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 EPS25972.1 - 0.01 15.1 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase Methyltransf_26 PF13659.1 EPS25972.1 - 0.083 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_21 PF05050.7 EPS25972.1 - 0.11 12.4 0.1 0.3 11.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase FkbM domain Lyase_aromatic PF00221.14 EPS25973.1 - 6.6e-152 506.2 0.1 9.5e-152 505.7 0.0 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase FAD_binding_3 PF01494.14 EPS25974.1 - 9.2e-79 265.0 0.0 1.1e-78 264.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EPS25974.1 - 2.3e-34 118.4 0.0 4.3e-34 117.5 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Thi4 PF01946.12 EPS25974.1 - 1.8e-05 23.9 0.1 2.9e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EPS25974.1 - 5.9e-05 21.7 0.3 8.5e-05 21.1 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EPS25974.1 - 0.00012 21.1 0.4 0.0002 20.3 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EPS25974.1 - 0.039 13.8 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EPS25974.1 - 0.041 12.7 0.0 0.37 9.5 0.0 2.1 1 1 0 1 1 1 0 Squalene epoxidase DAO PF01266.19 EPS25974.1 - 0.062 12.1 0.0 0.13 11.1 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPS25974.1 - 0.087 12.8 0.1 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EPS25974.1 - 0.098 11.7 0.3 0.15 11.0 0.2 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase SBF PF01758.11 EPS25975.1 - 4.9e-52 176.0 9.5 4.9e-52 176.0 6.6 2.2 2 2 0 2 2 2 1 Sodium Bile acid symporter family PsbI PF02532.9 EPS25975.1 - 0.31 10.6 2.9 1.5 8.4 2.0 2.2 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) MFS_1 PF07690.11 EPS25977.1 - 5.3e-27 94.4 30.2 5.3e-27 94.4 20.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily WD40 PF00400.27 EPS25978.1 - 1.9e-15 56.0 6.0 4.6e-05 23.1 0.0 5.7 6 1 0 6 6 6 4 WD domain, G-beta repeat Atg14 PF10186.4 EPS25978.1 - 2.1 7.2 5.3 0.43 9.4 1.0 1.7 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 ATP-synt_E PF05680.7 EPS25979.1 - 2.2e-24 85.2 0.7 2.4e-24 85.0 0.5 1.1 1 0 0 1 1 1 1 ATP synthase E chain UCR_14kD PF02271.11 EPS25979.1 - 0.013 15.2 0.1 0.017 14.9 0.1 1.1 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit Chordopox_A13L PF05961.6 EPS25979.1 - 0.3 11.0 1.1 0.7 9.8 0.8 1.7 1 1 0 1 1 1 0 Chordopoxvirus A13L protein PCI_Csn8 PF10075.4 EPS25980.1 - 1.4e-30 105.9 0.0 1.9e-30 105.4 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EPS25980.1 - 0.0013 18.3 0.0 0.0016 18.0 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family STT3 PF02516.9 EPS25981.1 - 1.6e-131 439.6 40.7 7.7e-127 424.1 26.8 2.0 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Coiled-coil_56 PF09813.4 EPS25982.1 - 9.1e-05 22.3 0.0 0.0001 22.2 0.0 1.1 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 56 DUF3453 PF11935.3 EPS25983.1 - 3.4e-70 236.1 0.0 6.8e-70 235.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) Sds3 PF08598.6 EPS25984.1 - 8e-28 97.3 2.1 8e-28 97.3 1.4 2.5 2 1 0 2 2 2 1 Sds3-like DUF1487 PF07368.6 EPS25984.1 - 0.011 14.9 0.6 0.85 8.8 0.0 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1487) Ku_PK_bind PF08785.6 EPS25984.1 - 0.12 12.3 0.2 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 Ku C terminal domain like RRM_1 PF00076.17 EPS25985.1 - 6.2e-06 25.7 1.2 0.0097 15.5 0.0 3.7 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS25985.1 - 0.00018 21.2 0.0 0.093 12.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS25985.1 - 0.00024 20.9 0.4 0.021 14.7 0.0 3.1 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Daxx PF03344.10 EPS25985.1 - 0.092 11.2 20.2 0.15 10.5 14.0 1.4 1 0 0 1 1 1 0 Daxx Family Ebola_NP PF05505.7 EPS25985.1 - 3.6 5.5 19.6 5 5.0 13.6 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Pyr_redox_3 PF13738.1 EPS25987.1 - 1.7e-30 106.6 0.0 2.7e-30 105.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPS25987.1 - 8.7e-07 29.0 0.0 1.4e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPS25987.1 - 4.3e-06 26.5 0.0 0.00019 21.2 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EPS25987.1 - 0.00013 20.9 0.0 0.0012 17.8 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 EPS25987.1 - 0.17 12.0 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GPI-anchored PF10342.4 EPS25989.1 - 1.1e-20 73.9 1.8 1.1e-20 73.9 1.3 2.5 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Gmad2 PF10648.4 EPS25989.1 - 0.029 14.5 2.2 0.16 12.1 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin-like domain of bacterial spore germination AKAP2_C PF15304.1 EPS25989.1 - 0.18 11.3 5.9 0.24 10.9 4.1 1.1 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus KAR9 PF08580.5 EPS25989.1 - 1 7.5 9.9 1 7.5 6.9 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF572 PF04502.8 EPS25989.1 - 1.1 8.4 4.3 1.3 8.1 3.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Rifin_STEVOR PF02009.11 EPS25989.1 - 1.1 8.8 3.8 1.1 8.8 2.6 1.2 1 0 0 1 1 1 0 Rifin/stevor family Herpes_TAF50 PF03326.8 EPS25989.1 - 2.4 7.0 14.7 2.8 6.8 10.2 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Macoilin PF09726.4 EPS25989.1 - 3.1 5.9 13.4 3.4 5.8 9.3 1.0 1 0 0 1 1 1 0 Transmembrane protein Peptidase_S64 PF08192.6 EPS25989.1 - 8.9 4.5 10.1 11 4.2 7.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 PAP1 PF08601.5 EPS25989.1 - 9.8 5.7 17.6 14 5.2 12.2 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 NUFIP1 PF10453.4 EPS25990.1 - 1.4e-15 56.4 3.0 1.4e-15 56.4 2.1 3.1 1 1 1 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.19 EPS25990.1 - 7.3e-08 31.9 3.6 1.2e-07 31.2 2.5 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RNA_pol_Rbc25 PF08292.7 EPS25991.1 - 1.3e-34 118.9 0.1 1.8e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EPS25991.1 - 8.3e-15 54.6 0.0 1.2e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Cys_Met_Meta_PP PF01053.15 EPS25992.1 - 3.1e-137 456.9 0.1 3.5e-137 456.7 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EPS25992.1 - 3.9e-09 35.9 0.1 5.2e-09 35.5 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EPS25992.1 - 4.8e-08 32.4 0.4 8e-08 31.7 0.3 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EPS25992.1 - 5.7e-07 28.6 0.6 1.3e-06 27.4 0.3 1.5 1 1 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EPS25992.1 - 7.2e-05 22.0 0.2 0.00013 21.1 0.2 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase MFS_1 PF07690.11 EPS25994.1 - 1.8e-12 46.6 46.8 1.1e-11 44.0 13.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.10 EPS25994.1 - 0.00067 18.4 3.3 0.00067 18.4 2.3 2.3 2 0 0 2 2 2 1 PUCC protein NAD_binding_10 PF13460.1 EPS25995.1 - 3.5e-06 27.1 0.0 7.5e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EPS25995.1 - 1e-05 24.9 0.0 4.9e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 NmrA-like family p450 PF00067.17 EPS25996.1 - 6.1e-52 176.6 0.0 8.4e-52 176.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ERG4_ERG24 PF01222.12 EPS25997.1 - 1.7e-137 458.5 16.1 1.9e-137 458.3 11.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.8 EPS25997.1 - 0.0078 16.3 3.4 0.0078 16.2 0.0 2.8 3 1 0 3 3 3 1 Phospholipid methyltransferase Methyltransf_16 PF10294.4 EPS25998.1 - 0.028 13.8 0.0 0.8 9.1 0.0 2.2 2 0 0 2 2 2 0 Putative methyltransferase DUF3584 PF12128.3 EPS26000.1 - 5.8e-06 23.9 70.7 0.002 15.5 32.6 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3584) Filament PF00038.16 EPS26000.1 - 0.0052 16.3 67.8 0.016 14.6 30.3 3.1 1 1 1 2 2 2 2 Intermediate filament protein zf-C2H2_jaz PF12171.3 EPS26002.1 - 0.69 10.1 10.5 1.2 9.3 0.2 3.8 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EPS26002.1 - 1.4 9.4 43.2 0.11 12.9 2.3 7.0 7 0 0 7 7 7 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EPS26002.1 - 6.1 7.3 35.6 0.78 10.2 3.5 6.5 6 0 0 6 6 6 0 Zinc finger, C2H2 type AAA PF00004.24 EPS26005.1 - 8e-49 165.2 0.0 5.4e-42 143.1 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EPS26005.1 - 3.9e-08 32.9 0.0 4.4e-06 26.2 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.1 EPS26005.1 - 2.4e-07 30.9 0.3 2.5e-05 24.3 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 EPS26005.1 - 4.6e-06 26.6 0.0 1.2e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EPS26005.1 - 2e-05 24.7 0.2 0.0007 19.7 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EPS26005.1 - 7.2e-05 22.5 0.0 0.00088 19.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EPS26005.1 - 8.3e-05 22.2 0.0 0.016 14.9 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain Sigma54_activ_2 PF14532.1 EPS26005.1 - 0.00015 21.8 0.0 0.097 12.7 0.0 2.8 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 EPS26005.1 - 0.00025 20.9 0.0 0.0044 16.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EPS26005.1 - 0.00048 20.9 0.1 0.013 16.3 0.0 3.3 4 0 0 4 4 2 1 AAA domain Bromodomain PF00439.20 EPS26005.1 - 0.0014 18.4 0.0 0.0038 17.1 0.0 1.7 1 0 0 1 1 1 1 Bromodomain AAA_25 PF13481.1 EPS26005.1 - 0.0025 17.2 0.0 0.0097 15.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EPS26005.1 - 0.003 17.4 0.0 0.016 15.1 0.0 2.3 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.17 EPS26005.1 - 0.0033 17.5 0.0 0.012 15.8 0.0 2.0 1 0 0 1 1 1 1 RNA helicase AAA_30 PF13604.1 EPS26005.1 - 0.0091 15.5 0.8 0.029 13.9 0.0 2.2 3 0 0 3 3 2 1 AAA domain TIP49 PF06068.8 EPS26005.1 - 0.012 14.3 0.0 0.018 13.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_18 PF13238.1 EPS26005.1 - 0.013 15.8 0.0 0.055 13.7 0.0 2.2 2 0 0 2 2 1 0 AAA domain RuvB_N PF05496.7 EPS26005.1 - 0.014 14.4 0.0 0.048 12.6 0.0 1.8 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 EPS26005.1 - 0.015 14.5 0.1 0.09 11.9 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EPS26005.1 - 0.016 14.9 0.0 0.22 11.1 0.0 2.5 2 1 0 2 2 2 0 NACHT domain ABC_tran PF00005.22 EPS26005.1 - 0.025 14.8 0.0 0.13 12.5 0.0 2.3 1 0 0 1 1 1 0 ABC transporter Parvo_NS1 PF01057.12 EPS26005.1 - 0.032 13.1 0.0 0.21 10.4 0.0 2.0 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 EPS26005.1 - 0.042 13.3 0.0 1.6 8.1 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_3 PF07726.6 EPS26005.1 - 0.046 13.3 0.0 0.14 11.8 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 EPS26005.1 - 0.069 12.1 0.1 0.2 10.6 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) MobB PF03205.9 EPS26005.1 - 0.087 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PhoH PF02562.11 EPS26005.1 - 0.13 11.4 0.0 0.28 10.3 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Torsin PF06309.6 EPS26005.1 - 0.15 11.9 0.0 0.55 10.1 0.0 1.9 2 0 0 2 2 1 0 Torsin Sec66 PF09802.4 EPS26006.1 - 3.4e-81 271.1 0.2 4e-81 270.9 0.1 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 DUF3848 PF12959.2 EPS26006.1 - 0.068 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3848) PPR_3 PF13812.1 EPS26007.1 - 7e-07 29.0 1.2 2.9 8.3 0.0 6.8 7 0 0 7 7 7 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 EPS26007.1 - 2.1e-06 27.6 0.3 0.12 12.3 0.0 4.3 4 0 0 4 4 4 2 PPR repeat family EcsC PF12787.2 EPS26007.1 - 0.081 12.3 0.0 9.1 5.5 0.0 2.7 1 1 1 2 2 2 0 EcsC protein family PPR PF01535.15 EPS26007.1 - 0.36 10.9 1.8 14 5.9 0.0 3.6 5 0 0 5 5 5 0 PPR repeat ORC3_N PF07034.6 EPS26008.1 - 4.6e-26 91.5 0.0 1.1e-24 87.0 0.0 2.3 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus HEAT_2 PF13646.1 EPS26009.1 - 0.0019 18.4 1.0 0.0066 16.6 0.3 2.2 1 1 2 3 3 3 1 HEAT repeats HEAT PF02985.17 EPS26009.1 - 0.0051 16.7 0.9 0.26 11.4 0.0 3.1 3 0 0 3 3 3 1 HEAT repeat TFIIA PF03153.8 EPS26009.1 - 0.041 13.7 2.2 0.044 13.6 1.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SURF2 PF05477.6 EPS26009.1 - 0.14 11.2 2.7 0.23 10.5 1.8 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) DUF2457 PF10446.4 EPS26009.1 - 1.8 7.1 15.7 2.5 6.7 10.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Daxx PF03344.10 EPS26009.1 - 2 6.7 8.9 3.7 5.9 6.2 1.4 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 EPS26009.1 - 4.1 5.3 9.3 1 7.2 4.4 1.4 2 0 0 2 2 2 0 CDC45-like protein Nucleoplasmin PF03066.10 EPS26009.1 - 4.7 6.7 9.3 7.7 6.0 6.4 1.4 1 0 0 1 1 1 0 Nucleoplasmin Nop14 PF04147.7 EPS26010.1 - 1.8e-278 925.9 36.5 2.1e-278 925.7 25.3 1.0 1 0 0 1 1 1 1 Nop14-like family Noc2 PF03715.8 EPS26010.1 - 0.063 12.1 0.2 0.18 10.6 0.0 1.8 2 0 0 2 2 2 0 Noc2p family Sulfotransfer_1 PF00685.22 EPS26011.1 - 0.00045 19.5 0.0 0.0043 16.3 0.0 2.2 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 EPS26011.1 - 0.0066 17.3 1.1 0.017 16.0 0.7 1.6 1 1 0 1 1 1 1 Sulfotransferase family Ank_2 PF12796.2 EPS26012.1 - 1.7e-49 166.0 0.4 7.3e-19 67.9 0.0 3.8 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EPS26012.1 - 2.1e-46 153.4 6.9 5.7e-07 29.0 0.0 8.1 8 0 0 8 8 8 8 Ankyrin repeat Ank_3 PF13606.1 EPS26012.1 - 1.7e-36 120.6 1.8 0.002 18.2 0.0 8.2 8 0 0 8 8 8 8 Ankyrin repeat Ank_5 PF13857.1 EPS26012.1 - 1.7e-36 123.4 5.7 6.3e-10 38.9 0.1 7.5 2 2 6 8 8 8 8 Ankyrin repeats (many copies) Ank_4 PF13637.1 EPS26012.1 - 1.4e-34 117.8 0.4 1.8e-11 44.1 0.0 5.2 3 2 2 5 5 5 5 Ankyrin repeats (many copies) COesterase PF00135.23 EPS26013.1 - 3.1e-97 326.5 0.0 3.5e-97 326.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EPS26013.1 - 6.1e-11 42.3 0.0 1.8e-10 40.7 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EPS26013.1 - 0.00034 19.9 0.3 0.00065 18.9 0.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EPS26013.1 - 0.0079 15.9 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family ComC PF03047.9 EPS26013.1 - 0.77 9.2 2.2 0.9 9.0 0.1 2.2 2 0 0 2 2 2 0 COMC family DUF4187 PF13821.1 EPS26014.1 - 3.4e-19 68.1 1.8 8.2e-19 66.9 1.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 EPS26014.1 - 4.5e-08 32.7 0.6 8.7e-07 28.6 0.1 2.5 2 0 0 2 2 2 1 G-patch domain MRP-S31 PF15433.1 EPS26014.1 - 0.11 11.9 11.7 0.011 15.1 2.6 2.1 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 FAR1 PF03101.10 EPS26016.1 - 3.9e-05 24.0 0.2 4.7e-05 23.8 0.1 1.1 1 0 0 1 1 1 1 FAR1 DNA-binding domain dTDP_sugar_isom PF00908.12 EPS26016.1 - 0.13 11.5 0.0 0.17 11.1 0.0 1.1 1 0 0 1 1 1 0 dTDP-4-dehydrorhamnose 3,5-epimerase DbpA PF03880.10 EPS26017.1 - 0.0053 16.3 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 DbpA RNA binding domain Peptidase_S49_N PF08496.5 EPS26018.1 - 0.24 11.1 9.6 1.2 8.9 2.8 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal MFS_1 PF07690.11 EPS26019.1 - 6.5e-30 104.0 35.5 5.2e-27 94.4 16.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS26019.1 - 1.2e-09 37.3 4.7 1.2e-09 37.3 3.2 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.8 EPS26019.1 - 0.16 10.0 9.7 0.068 11.2 1.5 2.7 2 1 1 3 3 3 0 Transmembrane secretion effector Kinetocho_Slk19 PF12709.2 EPS26020.1 - 3.2e-23 81.6 25.2 5.2e-22 77.7 5.2 4.2 3 1 2 5 5 5 2 Central kinetochore-associated THOC7 PF05615.8 EPS26020.1 - 0.43 10.8 25.5 0.31 11.2 4.6 3.4 2 1 1 3 3 3 0 Tho complex subunit 7 DUF4200 PF13863.1 EPS26020.1 - 0.54 10.2 40.0 0.25 11.3 7.0 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF4200) Fib_alpha PF08702.5 EPS26020.1 - 4 7.5 6.4 85 3.2 0.8 3.5 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family IncA PF04156.9 EPS26020.1 - 8.4 5.9 27.2 0.25 10.9 2.7 3.5 2 1 0 2 2 2 0 IncA protein Fungal_trans PF04082.13 EPS26023.1 - 4.4e-37 127.3 1.1 7.1e-37 126.6 0.8 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS26023.1 - 0.00073 19.4 17.6 0.0015 18.3 12.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RAP1 PF07218.6 EPS26023.1 - 3.1 5.7 3.6 4.9 5.1 2.5 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) T5orf172 PF10544.4 EPS26025.1 - 1.8e-09 37.9 0.0 5.5e-09 36.3 0.0 1.9 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.1 EPS26025.1 - 1.7e-06 28.3 1.0 3.7e-06 27.2 0.7 1.6 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 DUF480 PF04337.7 EPS26026.1 - 0.0039 17.0 0.0 0.0045 16.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF480 Peptidase_S10 PF00450.17 EPS26027.1 - 2.2e-108 363.1 3.8 2.6e-108 362.8 2.7 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase MFS_1 PF07690.11 EPS26028.1 - 9.4e-19 67.3 30.5 1.3e-18 66.8 21.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EPS26028.1 - 6.9e-11 41.8 4.6 6.9e-11 41.8 3.2 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Amidohydro_1 PF01979.15 EPS26029.1 - 1e-12 48.3 0.0 5.3e-08 32.8 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EPS26029.1 - 4.3e-10 40.0 2.4 1.3e-08 35.2 1.7 2.6 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EPS26029.1 - 8.5e-06 25.2 0.0 4.1e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 EPS26029.1 - 2.8e-05 23.8 0.0 8.3e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase GMC_oxred_N PF00732.14 EPS26030.1 - 4.6e-54 183.5 0.0 5.7e-54 183.2 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EPS26030.1 - 2e-38 131.9 0.0 3.3e-38 131.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EPS26030.1 - 4e-08 32.5 0.1 0.0039 16.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EPS26030.1 - 7.9e-07 28.2 0.2 0.0023 16.8 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPS26030.1 - 0.00021 21.2 0.1 0.00069 19.5 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EPS26030.1 - 0.00062 18.9 0.3 0.02 14.0 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EPS26030.1 - 0.00069 18.6 0.0 0.001 18.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EPS26030.1 - 0.0054 16.8 0.1 0.07 13.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPS26030.1 - 0.019 14.8 0.0 0.051 13.4 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EPS26030.1 - 0.068 12.0 0.3 0.7 8.6 0.1 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Aldedh PF00171.17 EPS26032.1 - 1.2e-154 515.0 0.1 1.4e-154 514.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family SLAP PF03217.9 EPS26032.1 - 0.092 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial surface layer protein Glucosamine_iso PF01182.15 EPS26033.1 - 1.7e-23 83.3 0.0 2.7e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Glyco_hydro_3 PF00933.16 EPS26034.1 - 7.2e-57 192.6 0.0 1.1e-56 192.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EPS26034.1 - 1.5e-06 27.8 0.2 4.2e-06 26.4 0.2 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Acetyltransf_1 PF00583.19 EPS26034.1 - 0.00021 21.2 0.0 0.0012 18.8 0.0 2.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPS26034.1 - 0.01 15.9 0.0 0.024 14.7 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 EPS26034.1 - 0.012 15.6 0.1 0.17 11.8 0.0 2.7 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain DUF4593 PF15263.1 EPS26034.1 - 0.058 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4593) NDT80_PhoG PF05224.7 EPS26037.1 - 1.4e-38 132.8 0.0 2.5e-38 131.9 0.0 1.5 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family PAT1 PF09770.4 EPS26037.1 - 2.6 6.1 13.7 3.8 5.6 9.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CPSF_A PF03178.10 EPS26038.1 - 1.4e-103 346.3 0.0 5.3e-103 344.4 0.0 2.0 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 EPS26038.1 - 6.5e-07 27.8 0.0 0.017 13.3 0.0 2.9 3 0 0 3 3 3 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term LMBR1 PF04791.11 EPS26039.1 - 1.6e-18 66.5 10.4 2.7e-17 62.5 0.6 2.4 2 0 0 2 2 2 2 LMBR1-like membrane protein Reo_sigmaC PF04582.7 EPS26040.1 - 0.088 11.9 0.3 0.091 11.9 0.2 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF904 PF06005.7 EPS26040.1 - 2.1 8.6 7.6 1.5e+02 2.7 5.3 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF904) IncA PF04156.9 EPS26040.1 - 2.5 7.6 5.1 3.2 7.3 3.6 1.3 1 0 0 1 1 1 0 IncA protein Atg14 PF10186.4 EPS26041.1 - 4.2e-95 318.1 2.1 5.2e-95 317.8 1.5 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Zip PF02535.17 EPS26042.1 - 1.4e-43 149.1 1.1 1.8e-43 148.7 0.8 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Thiolase_N PF00108.18 EPS26043.1 - 1.2e-96 322.7 0.2 1.7e-96 322.2 0.1 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EPS26043.1 - 2.5e-44 149.6 1.8 2.5e-44 149.6 1.3 1.9 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EPS26043.1 - 7.1e-06 25.6 4.3 9.6e-06 25.2 1.8 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EPS26043.1 - 0.0096 15.5 2.8 0.23 11.1 0.1 2.9 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GTP_EFTU PF00009.22 EPS26044.1 - 1.7e-44 151.5 0.0 4.2e-44 150.2 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EPS26044.1 - 6e-27 93.6 0.0 1.4e-26 92.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EPS26044.1 - 1.4e-19 69.7 0.0 3.7e-19 68.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EPS26044.1 - 4.6e-09 36.2 0.7 1e-08 35.1 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EPS26044.1 - 2.5e-07 30.4 0.1 1.9e-06 27.6 0.0 2.2 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EPS26044.1 - 4.7e-07 29.7 0.1 9.2e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EPS26044.1 - 0.0019 18.6 0.0 0.006 17.0 0.0 1.9 1 1 0 1 1 1 1 Miro-like protein Ras PF00071.17 EPS26044.1 - 0.012 15.0 0.0 0.055 12.8 0.0 2.0 2 0 0 2 2 2 0 Ras family SRPRB PF09439.5 EPS26044.1 - 0.12 11.5 0.2 1.3 8.1 0.1 2.6 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 EPS26044.1 - 0.17 11.7 3.0 4.4 7.0 0.1 2.7 2 1 1 3 3 3 0 Dynamin family DNA_pol_phi PF04931.8 EPS26044.1 - 3 5.5 8.8 31 2.1 6.0 2.0 2 0 0 2 2 2 0 DNA polymerase phi DUF59 PF01883.14 EPS26045.1 - 4.4e-08 32.9 0.0 8.7e-08 32.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF59 Zn_clus PF00172.13 EPS26047.1 - 2.8e-06 27.1 8.5 5.2e-06 26.2 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APC_CDC26 PF10471.4 EPS26048.1 - 3.4e-13 50.1 0.1 1.2e-12 48.4 0.0 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 RRF PF01765.14 EPS26050.1 - 1.3e-40 138.5 1.0 1.7e-40 138.1 0.7 1.1 1 0 0 1 1 1 1 Ribosome recycling factor PcfJ PF14284.1 EPS26050.1 - 0.12 11.8 1.4 0.21 11.0 0.9 1.4 1 0 0 1 1 1 0 PcfJ-like protein DUF3391 PF11871.3 EPS26050.1 - 0.89 9.7 7.3 9.3 6.4 0.7 2.7 2 2 1 3 3 3 0 Domain of unknown function (DUF3391) DUF883 PF05957.8 EPS26050.1 - 4.4 7.7 6.6 36 4.8 3.4 2.7 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) HSP70 PF00012.15 EPS26051.1 - 1e-231 770.0 8.2 1.2e-231 769.9 5.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EPS26051.1 - 2.4e-17 62.5 0.2 1.7e-16 59.7 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EPS26051.1 - 0.00028 20.5 0.0 0.00051 19.7 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain NAF PF03822.9 EPS26051.1 - 0.99 9.1 5.0 4.9 6.9 0.7 2.8 2 0 0 2 2 2 0 NAF domain Bromodomain PF00439.20 EPS26052.1 - 1.1e-14 54.0 0.0 2.1e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Bromodomain DUF2218 PF09981.4 EPS26052.1 - 0.056 13.6 0.0 0.66 10.1 0.0 2.5 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2218) Sfi1_C PF10638.4 EPS26052.1 - 0.54 10.7 4.7 0.98 9.8 1.1 2.5 1 1 1 2 2 2 0 Spindle body associated protein C-terminus CKS PF01111.14 EPS26053.1 - 2e-36 123.6 0.4 2e-36 123.6 0.3 1.6 2 0 0 2 2 2 1 Cyclin-dependent kinase regulatory subunit Thioredoxin_4 PF13462.1 EPS26054.1 - 1.4e-11 44.6 0.0 2.4e-11 43.8 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin DSBA PF01323.15 EPS26054.1 - 0.013 15.0 2.4 0.72 9.3 0.2 2.7 1 1 1 2 2 2 0 DSBA-like thioredoxin domain LysM PF01476.15 EPS26054.1 - 0.067 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 LysM domain DUF3844 PF12955.2 EPS26056.1 - 6.5e-40 135.3 2.9 1.1e-39 134.6 2.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) zf-RING_2 PF13639.1 EPS26057.1 - 3.1e-13 49.3 6.6 4.7e-13 48.7 4.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EPS26057.1 - 4.2e-08 32.7 4.4 6.7e-08 32.0 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EPS26057.1 - 1.3e-06 28.3 5.7 2.7e-06 27.4 3.9 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EPS26057.1 - 2.5e-06 27.1 3.9 3.8e-06 26.5 2.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EPS26057.1 - 9.3e-06 25.5 6.1 1.5e-05 24.9 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPS26057.1 - 7e-05 22.4 2.4 0.0001 21.8 1.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EPS26057.1 - 0.0026 17.5 3.1 0.0065 16.2 2.2 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EPS26057.1 - 0.04 13.4 6.4 0.067 12.7 4.4 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EPS26057.1 - 0.062 13.1 5.2 0.12 12.2 3.6 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PHD PF00628.24 EPS26057.1 - 0.077 12.7 5.5 0.15 11.7 3.8 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_UBOX PF13445.1 EPS26057.1 - 0.14 11.8 0.8 0.28 10.9 0.2 1.8 1 1 1 2 2 2 0 RING-type zinc-finger FANCL_C PF11793.3 EPS26057.1 - 0.44 10.5 3.4 1.2 9.1 2.3 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 EPS26057.1 - 0.75 9.8 5.8 1.4 9.0 4.0 1.5 1 0 0 1 1 1 0 RING-variant domain Pro_isomerase PF00160.16 EPS26058.1 - 3.4e-47 160.5 1.0 3.8e-47 160.3 0.7 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD tRNA-synt_2c PF01411.14 EPS26059.1 - 8.6e-220 730.7 0.1 1.1e-219 730.2 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EPS26059.1 - 2e-16 59.6 0.9 4.4e-16 58.4 0.6 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 EPS26059.1 - 0.00023 20.7 0.6 0.00061 19.4 0.4 1.8 1 0 0 1 1 1 1 DHHA1 domain Mucin PF01456.12 EPS26060.1 - 0.0092 15.7 6.8 0.0092 15.7 4.7 1.6 2 0 0 2 2 2 1 Mucin-like glycoprotein SseC PF04888.7 EPS26062.1 - 0.0051 16.1 9.4 0.0057 16.0 6.5 1.0 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family YpjP PF14005.1 EPS26062.1 - 0.011 15.4 1.8 0.014 15.1 1.2 1.2 1 0 0 1 1 1 0 YpjP-like protein Mor PF08765.6 EPS26062.1 - 0.026 14.2 1.0 0.32 10.7 0.6 2.2 1 1 0 1 1 1 0 Mor transcription activator family Toxin_43 PF15604.1 EPS26062.1 - 0.056 13.4 2.3 0.064 13.3 1.6 1.0 1 0 0 1 1 1 0 Putative toxin 43 Flexi_CP PF00286.15 EPS26062.1 - 0.24 11.0 6.7 0.28 10.8 4.6 1.1 1 0 0 1 1 1 0 Viral coat protein UPF0172 PF03665.8 EPS26062.1 - 0.79 9.1 4.0 0.87 9.0 2.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) CAS_CSE1 PF03378.10 EPS26062.1 - 1.8 6.7 6.1 2 6.6 4.2 1.0 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus OmpH PF03938.9 EPS26063.1 - 0.0017 18.3 1.4 0.0017 18.3 1.0 1.6 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) DUF2268 PF10026.4 EPS26063.1 - 0.043 13.1 0.0 0.097 12.0 0.0 1.5 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) DUF2011 PF09428.5 EPS26063.1 - 0.15 11.9 9.3 0.82 9.5 7.0 1.8 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF2011) DUF3425 PF11905.3 EPS26065.1 - 2e-15 56.8 0.3 3.9e-15 55.9 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) MGDG_synth PF06925.6 EPS26065.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Monogalactosyldiacylglycerol (MGDG) synthase NmrA PF05368.8 EPS26066.1 - 3.7e-36 124.5 0.0 5e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPS26066.1 - 5.8e-09 36.2 0.1 3.4e-08 33.7 0.0 1.9 2 0 0 2 2 2 1 NADH(P)-binding adh_short PF00106.20 EPS26066.1 - 7.1e-05 22.7 0.1 0.00018 21.4 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.16 EPS26066.1 - 0.0014 18.1 0.0 0.0021 17.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EPS26066.1 - 0.019 14.5 0.0 0.073 12.7 0.0 1.8 2 0 0 2 2 2 0 KR domain Mito_carr PF00153.22 EPS26067.1 - 1.2e-71 236.4 4.3 4.9e-23 80.6 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tom7 PF08038.7 EPS26068.1 - 2.5e-20 71.6 0.3 2.9e-20 71.4 0.2 1.1 1 0 0 1 1 1 1 TOM7 family RRM_1 PF00076.17 EPS26069.1 - 3.4e-34 116.3 0.0 8.8e-16 57.3 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS26069.1 - 4.4e-18 65.0 0.0 1.3e-08 34.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS26069.1 - 1.6e-15 56.6 0.0 1.5e-06 27.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EPS26069.1 - 0.0042 16.5 0.1 0.45 10.0 0.0 2.4 2 0 0 2 2 2 1 Ribonuclease B OB domain Limkain-b1 PF11608.3 EPS26069.1 - 0.081 12.6 0.1 1.7 8.4 0.0 2.1 2 0 0 2 2 2 0 Limkain b1 DUF2015 PF09435.5 EPS26070.1 - 1.4e-49 167.1 0.0 1.6e-49 166.9 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Ribosomal_L28e PF01778.12 EPS26071.1 - 1.2e-42 144.9 0.8 1.5e-42 144.6 0.6 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family DUF2559 PF10832.3 EPS26071.1 - 0.83 9.4 3.8 6.7 6.5 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2559) Ldh_1_N PF00056.18 EPS26072.1 - 6.7e-46 155.6 0.0 9.3e-46 155.1 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EPS26072.1 - 3.2e-41 140.9 0.0 4.3e-41 140.5 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EPS26072.1 - 0.00047 18.9 0.0 0.00088 18.0 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.11 EPS26072.1 - 0.003 16.9 0.1 0.2 10.9 0.0 2.3 1 1 1 2 2 2 2 Family 4 glycosyl hydrolase THF_DHG_CYH_C PF02882.14 EPS26072.1 - 0.042 12.9 0.1 0.6 9.1 0.1 2.6 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TRAPP PF04051.11 EPS26073.1 - 3.6e-46 156.4 0.0 4.1e-46 156.2 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PorB PF11565.3 EPS26073.1 - 0.049 13.8 0.0 0.087 13.0 0.0 1.4 1 0 0 1 1 1 0 Alpha helical Porin B PINIT PF14324.1 EPS26074.1 - 2.1e-40 138.1 0.2 3.6e-40 137.3 0.1 1.3 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 EPS26074.1 - 2e-21 75.2 7.3 3.4e-21 74.4 5.0 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.22 EPS26074.1 - 9e-11 41.0 0.3 8.1e-10 37.9 0.0 2.3 2 0 0 2 2 2 1 SAP domain zf-Nse PF11789.3 EPS26074.1 - 1.8e-06 27.3 2.8 4.3e-06 26.1 1.9 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DUF2423 PF10338.4 EPS26075.1 - 1.5e-19 69.6 2.6 3.9e-19 68.3 1.8 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) Phosphodiest PF01663.17 EPS26076.1 - 8.9e-18 64.7 1.4 1.9e-16 60.3 1.0 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EPS26076.1 - 2.4e-05 23.7 0.1 0.0018 17.5 0.0 2.4 3 0 0 3 3 3 2 Sulfatase Metalloenzyme PF01676.13 EPS26076.1 - 0.036 13.4 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 Metalloenzyme superfamily DUF229 PF02995.12 EPS26076.1 - 0.13 10.6 0.0 0.2 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Ribosomal_60s PF00428.14 EPS26077.1 - 0.018 15.4 3.1 0.036 14.4 2.1 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Cdd1 PF11731.3 EPS26077.1 - 0.16 11.9 0.5 0.31 10.9 0.3 1.4 1 0 0 1 1 1 0 Pathogenicity locus LZ_Tnp_IS66 PF13007.2 EPS26077.1 - 1.9 9.2 5.9 0.31 11.7 0.9 1.9 2 0 0 2 2 2 0 Transposase C of IS166 homeodomain DUF3787 PF12655.2 EPS26078.1 - 0.0022 17.6 4.5 0.0042 16.7 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3787) Sec15 PF04091.7 EPS26079.1 - 1.4e-117 392.4 2.4 3e-117 391.3 1.7 1.6 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like COG2 PF06148.6 EPS26079.1 - 0.00011 22.0 2.8 0.00011 22.0 1.9 3.0 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.4 EPS26079.1 - 0.00026 20.9 6.6 0.00094 19.1 2.8 2.8 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Sec5 PF15469.1 EPS26079.1 - 0.00089 19.0 0.7 0.00089 19.0 0.5 3.2 3 1 1 4 4 4 1 Exocyst complex component Sec5 DUF2450 PF10475.4 EPS26079.1 - 0.0014 17.6 4.1 0.0014 17.6 2.9 1.9 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) Sec8_exocyst PF04048.9 EPS26079.1 - 0.006 16.2 1.6 0.006 16.2 1.1 3.2 3 1 0 3 3 3 1 Sec8 exocyst complex component specific domain Vps51 PF08700.6 EPS26079.1 - 0.015 15.0 1.9 0.044 13.6 0.2 2.6 2 0 0 2 2 2 0 Vps51/Vps67 CBFD_NFYB_HMF PF00808.18 EPS26080.1 - 3.6e-19 68.5 0.6 6e-19 67.8 0.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EPS26080.1 - 1.7e-12 47.2 0.1 3e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 EPS26080.1 - 0.028 14.2 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Etmic-2 PF06670.6 EPS26080.1 - 0.086 11.5 0.1 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Microneme protein Etmic-2 Fcf2 PF08698.6 EPS26081.1 - 3.6e-33 113.5 0.7 3.6e-33 113.5 0.5 1.7 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing PNP_UDP_1 PF01048.15 EPS26082.1 - 2.6e-51 173.8 0.2 3.3e-51 173.5 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Ribosomal_S10 PF00338.17 EPS26083.1 - 6.2e-26 90.0 0.0 9.8e-26 89.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF3530 PF12048.3 EPS26083.1 - 1.4 7.8 5.6 2.6 6.9 3.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) tRNA-synt_1b PF00579.20 EPS26084.1 - 1.2e-75 254.3 0.0 1.5e-75 254.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) DUF883 PF05957.8 EPS26084.1 - 0.02 15.3 1.0 0.049 14.0 0.7 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Asp PF00026.18 EPS26085.1 - 1e-72 245.1 0.8 1.2e-72 244.8 0.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EPS26085.1 - 5.7e-12 45.8 0.6 2.3e-11 43.9 0.1 2.3 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EPS26085.1 - 7.5e-09 35.9 1.2 0.021 15.2 0.1 4.2 3 1 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 EPS26085.1 - 0.0015 18.0 0.0 0.0082 15.7 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 EPS26085.1 - 0.067 13.0 0.0 11 5.9 0.0 3.2 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease Methyltransf_26 PF13659.1 EPS26086.1 - 7.8e-13 48.4 0.0 3.7e-12 46.3 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPS26086.1 - 4e-08 32.9 0.0 9e-08 31.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS26086.1 - 8.1e-08 32.8 0.0 2.3e-07 31.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPS26086.1 - 0.00021 21.5 0.0 0.00047 20.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPS26086.1 - 0.00032 20.0 0.0 0.092 12.1 0.0 2.9 3 0 0 3 3 3 1 Methyltransferase small domain N6_Mtase PF02384.11 EPS26086.1 - 0.00075 18.6 0.0 0.11 11.4 0.0 2.1 2 0 0 2 2 2 2 N-6 DNA Methylase PrmA PF06325.8 EPS26086.1 - 0.0051 15.9 0.0 0.0084 15.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 EPS26086.1 - 0.054 13.1 0.0 0.11 12.1 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EPS26086.1 - 0.081 13.4 0.0 0.21 12.1 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EPS26086.1 - 0.12 12.8 0.0 0.27 11.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain FA_hydroxylase PF04116.8 EPS26087.1 - 5.1e-13 49.4 19.3 5.1e-13 49.4 13.4 2.3 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily WD40 PF00400.27 EPS26088.1 - 3.5e-75 245.4 8.9 1.3e-12 47.0 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 EPS26088.1 - 2.4e-26 91.7 11.8 3.5e-26 91.1 8.2 1.3 1 0 0 1 1 1 1 Tup N-terminal Cytochrom_D1 PF02239.11 EPS26088.1 - 4.4e-05 21.9 0.5 0.00059 18.2 0.2 2.5 1 1 1 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.3 EPS26088.1 - 0.00034 18.8 0.2 0.15 10.2 0.0 2.8 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 EPS26088.1 - 0.014 14.4 0.0 4.6 6.2 0.0 2.8 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.1 EPS26088.1 - 0.088 12.2 1.5 6 6.2 0.1 2.9 2 1 1 3 3 3 0 PQQ-like domain DUF853 PF05872.7 EPS26088.1 - 0.097 11.0 0.6 0.13 10.5 0.4 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) zf-H2C2_2 PF13465.1 EPS26089.1 - 1.7e-20 72.1 18.1 2.3e-09 37.0 1.3 4.8 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.21 EPS26089.1 - 1.9e-14 53.0 34.4 0.00028 21.0 0.5 5.2 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPS26089.1 - 2.3e-10 40.0 31.1 0.00052 20.1 0.3 5.1 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.2 EPS26089.1 - 0.0015 18.6 5.7 0.058 13.6 0.0 4.3 3 0 0 3 3 3 1 Zinc-finger of C2H2 type Ogr_Delta PF04606.7 EPS26089.1 - 0.15 11.7 0.1 0.15 11.7 0.1 3.7 3 1 1 4 4 4 0 Ogr/Delta-like zinc finger MRI PF15325.1 EPS26089.1 - 6.5 7.7 13.7 7.1 7.6 2.0 3.5 3 0 0 3 3 3 0 Modulator of retrovirus infection MIF4G_like PF09088.6 EPS26090.1 - 7.4e-84 279.9 0.0 1.3e-83 279.1 0.0 1.4 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 EPS26090.1 - 5.3e-61 206.0 0.0 8.9e-61 205.3 0.0 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G PF02854.14 EPS26090.1 - 0.00026 20.4 0.2 0.00087 18.7 0.0 2.0 2 0 0 2 2 2 1 MIF4G domain WD40 PF00400.27 EPS26091.1 - 3.1e-59 194.8 23.3 2.7e-08 33.3 0.0 12.6 13 0 0 13 13 13 9 WD domain, G-beta repeat BBS2_Mid PF14783.1 EPS26091.1 - 4.9e-07 29.4 0.0 3 7.6 0.0 5.8 7 0 0 7 7 7 3 Ciliary BBSome complex subunit 2, middle region Urm1 PF09138.6 EPS26092.1 - 6.8e-36 122.2 0.0 7.8e-36 122.0 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 EPS26092.1 - 0.00029 21.1 0.0 0.00035 20.9 0.0 1.2 1 0 0 1 1 1 1 ThiS family 6PF2K PF01591.13 EPS26093.1 - 4.7e-65 218.7 0.0 6.3e-65 218.3 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EPS26093.1 - 7.2e-22 78.1 0.6 1.2e-21 77.4 0.4 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_17 PF13207.1 EPS26093.1 - 4.1e-05 24.3 0.1 0.00042 21.1 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EPS26093.1 - 0.0014 18.5 0.0 0.0035 17.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EPS26093.1 - 0.0092 15.2 0.0 0.016 14.4 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 APS_kinase PF01583.15 EPS26093.1 - 0.043 13.4 0.0 0.52 9.9 0.0 2.3 1 1 0 1 1 1 0 Adenylylsulphate kinase Porin_3 PF01459.17 EPS26094.1 - 3.1e-81 272.6 0.0 3.6e-81 272.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic porin Zds_C PF08632.5 EPS26094.1 - 0.0028 17.0 0.0 0.0065 15.8 0.0 1.6 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Pkinase PF00069.20 EPS26095.1 - 1.2e-64 217.9 0.0 1.4e-64 217.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS26095.1 - 5.2e-25 87.9 0.0 6.5e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPS26095.1 - 1e-06 27.9 0.0 4.3e-06 25.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EPS26095.1 - 0.0011 18.8 0.1 0.023 14.4 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family rpo132 PF12415.3 EPS26095.1 - 0.032 13.1 0.7 0.91 8.5 0.0 2.5 2 0 0 2 2 2 0 Poxvirus DNA dependent RNA polymerase DUF1556 PF07590.6 EPS26097.1 - 3.4 7.9 7.0 0.65 10.2 0.3 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF1556) ABC_tran PF00005.22 EPS26098.1 - 1e-15 58.2 0.2 9.3e-15 55.1 0.1 2.1 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EPS26098.1 - 3.3e-10 40.4 0.9 0.00025 21.1 0.3 2.1 1 1 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EPS26098.1 - 4.6e-05 22.6 0.0 0.094 11.7 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EPS26098.1 - 0.00022 20.6 0.2 0.00042 19.7 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.14 EPS26098.1 - 0.00033 19.9 0.0 0.15 11.2 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain PduV-EutP PF10662.4 EPS26098.1 - 0.0012 18.3 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation DUF3584 PF12128.3 EPS26098.1 - 0.0018 15.7 0.2 0.0026 15.2 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_24 PF13479.1 EPS26098.1 - 0.0033 17.0 1.0 0.88 9.1 0.2 2.3 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EPS26098.1 - 0.0064 16.8 0.0 0.011 16.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EPS26098.1 - 0.011 15.1 0.1 0.022 14.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EPS26098.1 - 0.014 14.8 0.1 0.031 13.7 0.0 1.6 1 1 1 2 2 2 0 FtsK/SpoIIIE family DUF258 PF03193.11 EPS26098.1 - 0.015 14.4 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EPS26098.1 - 0.026 14.4 1.6 0.093 12.7 1.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 EPS26098.1 - 0.043 14.6 0.5 0.11 13.3 0.3 1.9 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EPS26098.1 - 0.044 13.6 0.0 0.32 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EPS26098.1 - 0.05 13.5 0.9 0.095 12.6 0.6 1.4 1 0 0 1 1 1 0 AAA domain Arf PF00025.16 EPS26098.1 - 0.075 12.2 0.2 0.16 11.2 0.1 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA PF00004.24 EPS26098.1 - 0.089 12.9 0.3 0.6 10.3 0.2 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EPS26098.1 - 0.1 12.0 0.1 0.14 11.5 0.0 1.3 1 1 0 1 1 1 0 AAA-like domain AAA_22 PF13401.1 EPS26098.1 - 0.14 12.3 0.9 0.66 10.1 0.1 2.2 2 1 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EPS26098.1 - 0.15 11.6 0.1 0.3 10.7 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Dynamin_N PF00350.18 EPS26098.1 - 0.15 11.8 0.1 0.25 11.1 0.1 1.3 1 0 0 1 1 1 0 Dynamin family AAA_13 PF13166.1 EPS26098.1 - 0.17 10.2 0.1 0.24 9.8 0.1 1.1 1 0 0 1 1 1 0 AAA domain IPPT PF01715.12 EPS26099.1 - 1.5e-52 178.1 0.5 7.1e-52 175.9 0.3 1.9 1 1 0 1 1 1 1 IPP transferase zf-C2H2_jaz PF12171.3 EPS26099.1 - 0.00023 21.2 0.1 0.00043 20.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AAA_17 PF13207.1 EPS26099.1 - 0.00025 21.8 1.6 0.00076 20.2 0.0 2.5 3 2 0 3 3 2 1 AAA domain AAA_33 PF13671.1 EPS26099.1 - 0.00041 20.2 0.0 0.14 12.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EPS26099.1 - 0.0032 17.7 0.2 0.43 10.8 0.0 3.1 2 1 1 3 3 3 1 AAA domain DUF3449 PF11931.3 EPS26099.1 - 0.0042 16.6 0.1 0.0097 15.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) IPT PF01745.11 EPS26099.1 - 0.0045 16.1 0.0 0.0092 15.1 0.0 1.4 1 0 0 1 1 1 1 Isopentenyl transferase zf-met PF12874.2 EPS26099.1 - 0.0072 16.5 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type AAA_25 PF13481.1 EPS26099.1 - 0.0093 15.3 0.0 0.12 11.7 0.0 2.5 3 0 0 3 3 3 1 AAA domain zf-C2H2_2 PF12756.2 EPS26099.1 - 0.088 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Las1 PF04031.8 EPS26099.1 - 0.11 12.0 0.1 0.27 10.8 0.0 1.7 2 0 0 2 2 2 0 Las1-like AAA_22 PF13401.1 EPS26099.1 - 0.13 12.4 0.0 0.36 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain RAI1 PF08652.6 EPS26100.1 - 1.8e-30 104.5 0.1 3.4e-30 103.6 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease DUF410 PF04190.8 EPS26101.1 - 5e-42 144.2 0.0 6.2e-42 143.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Lipid_DES PF08557.5 EPS26101.1 - 0.088 12.0 0.7 0.16 11.2 0.5 1.4 1 0 0 1 1 1 0 Sphingolipid Delta4-desaturase (DES) HpaP PF09483.5 EPS26102.1 - 0.45 10.4 5.1 0.74 9.7 3.5 1.3 1 0 0 1 1 1 0 Type III secretion protein (HpaP) Rep_fac_C PF08542.6 EPS26103.1 - 6.9e-22 77.2 0.0 1.7e-21 75.9 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 EPS26103.1 - 1.9e-11 44.2 0.0 3.4e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EPS26103.1 - 7.2e-11 42.0 0.0 6.1e-09 35.7 0.0 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA_14 PF13173.1 EPS26103.1 - 4.3e-08 33.0 0.0 1.8e-07 31.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EPS26103.1 - 6.4e-07 29.5 0.1 1.3e-05 25.2 0.0 2.5 1 1 2 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EPS26103.1 - 2.4e-06 27.7 0.0 0.004 17.2 0.0 2.5 1 1 1 2 2 2 2 AAA domain Rad17 PF03215.10 EPS26103.1 - 3.1e-06 26.1 0.0 0.0067 15.1 0.0 2.4 2 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_3 PF07726.6 EPS26103.1 - 4.2e-06 26.3 0.0 7.5e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EPS26103.1 - 4.3e-06 25.9 0.1 1.9e-05 23.8 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Viral_helicase1 PF01443.13 EPS26103.1 - 1.4e-05 24.6 0.0 2.3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DNA_pol3_delta PF06144.8 EPS26103.1 - 0.00045 19.7 0.0 0.00069 19.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_10 PF12846.2 EPS26103.1 - 0.00046 19.7 0.0 0.038 13.4 0.0 2.3 1 1 1 2 2 2 1 AAA-like domain Mg_chelatase PF01078.16 EPS26103.1 - 0.00057 19.1 0.0 0.005 16.0 0.0 2.1 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI ArgK PF03308.11 EPS26103.1 - 0.0014 17.4 0.0 0.0028 16.4 0.0 1.5 1 0 0 1 1 1 1 ArgK protein AAA_18 PF13238.1 EPS26103.1 - 0.002 18.4 0.0 0.0037 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 EPS26103.1 - 0.0032 17.1 0.0 0.011 15.4 0.0 1.9 2 0 0 2 2 2 1 NTPase KTI12 PF08433.5 EPS26103.1 - 0.0036 16.5 0.0 0.0062 15.7 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 FtsK_SpoIIIE PF01580.13 EPS26103.1 - 0.0043 16.5 0.0 0.0083 15.6 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_19 PF13245.1 EPS26103.1 - 0.0063 16.2 0.0 0.017 14.8 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EPS26103.1 - 0.035 14.9 0.0 0.074 13.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain DEAD PF00270.24 EPS26103.1 - 0.041 13.3 0.1 1.4 8.3 0.0 2.5 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_25 PF13481.1 EPS26103.1 - 0.051 12.9 0.1 0.38 10.1 0.0 2.5 3 1 0 3 3 2 0 AAA domain AAA_5 PF07728.9 EPS26103.1 - 0.054 13.2 0.0 0.16 11.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EPS26103.1 - 0.06 13.2 0.0 0.12 12.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EPS26103.1 - 0.063 12.9 0.0 0.2 11.3 0.0 1.7 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.17 EPS26103.1 - 0.064 12.0 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 EPS26103.1 - 0.066 13.3 0.0 0.19 11.9 0.0 1.8 2 0 0 2 2 1 0 RNA helicase AAA_11 PF13086.1 EPS26103.1 - 0.066 12.7 0.0 0.11 11.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_31 PF13614.1 EPS26103.1 - 0.088 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 EPS26103.1 - 0.12 11.6 0.1 0.38 10.0 0.0 1.8 2 0 0 2 2 2 0 Thymidylate kinase AAA_28 PF13521.1 EPS26103.1 - 0.13 12.1 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Fungal_trans PF04082.13 EPS26104.1 - 2.2e-11 43.1 1.2 2.6e-11 42.9 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS26104.1 - 2.6e-09 36.8 9.9 2.6e-09 36.8 6.9 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain T4_Gp59_C PF08994.5 EPS26104.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 T4 gene Gp59 loader of gp41 DNA helicase C-term Glyco_hydro_32N PF00251.15 EPS26105.1 - 3e-42 145.0 0.0 1.2e-41 143.1 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 EPS26105.1 - 3e-08 33.9 0.1 7e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR PF02012.15 EPS26105.1 - 0.0033 16.9 1.0 0.51 10.3 0.0 3.2 2 0 0 2 2 2 1 BNR/Asp-box repeat Sugar_tr PF00083.19 EPS26106.1 - 1.5e-73 247.9 16.4 1.8e-73 247.6 11.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS26106.1 - 1.2e-24 86.6 37.5 4.7e-24 84.7 13.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily AA_permease_2 PF13520.1 EPS26107.1 - 3.2e-69 233.5 35.0 4.3e-69 233.1 24.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPS26107.1 - 2e-28 98.9 23.8 2e-28 98.9 16.5 2.4 2 1 0 2 2 2 2 Amino acid permease FAD_binding_6 PF00970.19 EPS26108.1 - 1e-05 25.5 0.0 4.4e-05 23.5 0.0 2.2 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EPS26108.1 - 5.8e-05 23.6 0.0 0.03 14.8 0.0 2.3 1 1 0 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EPS26108.1 - 0.012 15.5 0.0 0.02 14.7 0.0 1.5 1 1 0 1 1 1 0 Ferric reductase NAD binding domain Aminotran_5 PF00266.14 EPS26109.1 - 1.8e-27 96.0 0.0 3.5e-17 62.2 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Aconitase PF00330.15 EPS26110.1 - 3.4e-68 230.2 0.5 5.2e-43 147.1 0.0 2.5 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EPS26110.1 - 2.7e-23 82.5 0.0 5.3e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Chorismate_bind PF00425.13 EPS26112.1 - 1.9e-65 220.7 0.0 2.1e-63 214.0 0.0 2.2 1 1 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 EPS26112.1 - 4.1e-26 91.6 0.0 7.5e-26 90.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 EPS26112.1 - 1.5e-11 44.4 0.0 6.3e-11 42.4 0.0 2.2 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 EPS26112.1 - 0.0019 17.7 0.6 0.018 14.4 0.4 2.3 1 1 0 1 1 1 1 Peptidase C26 DUF3684 PF12449.3 EPS26113.1 - 0 1529.2 0.0 0 1528.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 EPS26113.1 - 2e-05 24.2 0.0 5e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EPS26113.1 - 0.002 17.8 0.0 0.0058 16.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase WLM PF08325.5 EPS26113.1 - 0.14 11.9 4.8 0.68 9.7 0.1 2.4 2 0 0 2 2 2 0 WLM domain TRAPPC9-Trs120 PF08626.6 EPS26114.1 - 2.2e-154 515.5 0.0 2.7e-154 515.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_12 PF13424.1 EPS26114.1 - 0.07 13.0 0.1 0.19 11.7 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat adh_short PF00106.20 EPS26115.1 - 2.1e-24 86.3 0.0 2.9e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPS26115.1 - 5.9e-15 55.3 0.0 9e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPS26115.1 - 3.8e-07 29.7 0.0 6.5e-07 29.0 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EPS26115.1 - 4.7e-05 22.4 0.0 5.9e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EPS26115.1 - 0.00013 21.0 0.0 0.00018 20.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EPS26115.1 - 0.001 17.8 0.0 0.0014 17.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EPS26115.1 - 0.0079 15.4 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPS26115.1 - 0.0083 16.1 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Synaptonemal_3 PF15191.1 EPS26115.1 - 0.032 13.9 0.0 0.06 13.0 0.0 1.4 1 0 0 1 1 1 0 Synaptonemal complex central element protein 3 NAD_binding_4 PF07993.7 EPS26115.1 - 0.041 12.8 0.1 1.7 7.4 0.0 2.5 1 1 1 2 2 2 0 Male sterility protein DapB_N PF01113.15 EPS26115.1 - 0.064 13.1 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Sec1 PF00995.18 EPS26116.1 - 6.3e-149 497.2 0.0 7.1e-149 497.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family MBOAT PF03062.14 EPS26117.1 - 2.5e-49 168.1 5.0 4.3e-49 167.3 3.5 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Synaptobrevin PF00957.16 EPS26118.1 - 0.0048 16.4 1.8 0.01 15.4 1.2 1.5 1 0 0 1 1 1 1 Synaptobrevin Ni_hydr_CYTB PF01292.15 EPS26118.1 - 0.089 12.1 0.1 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 Abi PF02517.11 EPS26120.1 - 1.1e-14 54.3 17.6 6.5e-14 51.8 6.1 3.0 2 1 1 3 3 3 2 CAAX protease self-immunity DUF4244 PF14029.1 EPS26120.1 - 1.3 8.1 3.7 0.64 9.1 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4244) Methyltransf_25 PF13649.1 EPS26121.1 - 9.5e-08 32.3 0.0 2.9e-07 30.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPS26121.1 - 0.12 11.9 0.0 0.29 10.7 0.0 1.6 1 1 1 2 2 2 0 Methyltransferase domain Epimerase PF01370.16 EPS26122.1 - 9.8e-09 34.9 0.1 7.3e-05 22.3 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPS26122.1 - 1.2e-06 27.5 0.1 2.6e-06 26.3 0.1 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EPS26122.1 - 1.9e-06 28.0 0.3 3.1e-06 27.3 0.2 1.5 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EPS26122.1 - 1.8e-05 24.0 0.2 3.1e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EPS26122.1 - 0.00063 19.7 0.2 0.001 18.9 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EPS26122.1 - 0.0047 15.8 0.1 0.14 11.0 0.0 2.3 2 1 0 2 2 2 1 Male sterility protein Saccharop_dh PF03435.13 EPS26122.1 - 0.0053 15.7 0.2 0.0081 15.1 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase tRNA-synt_1 PF00133.17 EPS26123.1 - 9.4e-57 192.3 0.0 2.2e-36 125.0 0.0 6.1 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 EPS26123.1 - 2.7e-40 137.6 0.0 4.3e-40 136.9 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 EPS26123.1 - 8.6e-29 100.3 0.0 8.7e-23 80.6 0.0 4.0 3 1 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EPS26123.1 - 1.9e-08 34.2 0.0 4.1e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.14 EPS26123.1 - 0.0055 15.5 0.0 0.011 14.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (R) tRNA-synt_1e PF01406.14 EPS26123.1 - 0.25 10.4 0.0 1.7 7.6 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Suc_Fer-like PF06999.7 EPS26125.1 - 3.1e-46 158.2 0.0 4.2e-46 157.8 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like DUF3669 PF12417.3 EPS26127.1 - 5.3e-25 86.9 0.1 6e-24 83.5 0.1 2.2 2 0 0 2 2 2 1 Zinc finger protein p450 PF00067.17 EPS26128.1 - 2.9e-31 108.4 0.0 3.8e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_11 PF08241.7 EPS26129.1 - 1.8e-10 41.1 0.0 3.2e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPS26129.1 - 1.6e-09 37.5 0.0 2.1e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPS26129.1 - 4.5e-09 35.7 0.0 7.5e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EPS26129.1 - 5.6e-07 29.8 0.0 9e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPS26129.1 - 2.8e-05 24.1 0.0 5.1e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPS26129.1 - 5e-05 23.6 0.0 7.8e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPS26129.1 - 0.00047 19.8 0.0 0.0008 19.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS26129.1 - 0.0034 17.9 0.0 0.0064 17.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EPS26129.1 - 0.017 14.8 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EPS26129.1 - 0.041 13.2 0.0 0.46 9.8 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Trp_DMAT PF11991.3 EPS26130.1 - 1.6e-104 350.0 0.0 1.9e-104 349.7 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase MFS_1 PF07690.11 EPS26131.1 - 5.1e-43 147.1 44.7 1e-42 146.1 31.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EPS26131.1 - 6.4e-12 44.4 20.4 1.6e-11 43.1 14.2 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FAD_binding_3 PF01494.14 EPS26132.1 - 1.1e-17 64.0 3.0 2.5e-09 36.6 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.19 EPS26132.1 - 1.5e-09 37.2 5.5 5e-05 22.3 0.4 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPS26132.1 - 2.1e-06 26.8 0.3 3.5e-06 26.1 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EPS26132.1 - 0.00018 20.6 1.3 0.0003 19.9 0.9 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EPS26132.1 - 0.00025 20.1 0.1 0.00041 19.3 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EPS26132.1 - 0.00052 19.9 0.5 0.0011 18.9 0.4 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EPS26132.1 - 0.00085 17.8 0.5 0.019 13.4 0.2 2.2 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 EPS26132.1 - 0.066 13.2 0.2 0.31 11.1 0.1 2.3 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EPS26132.1 - 0.21 11.9 1.0 30 5.1 0.3 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_2 PF00891.13 EPS26133.1 - 9.8e-22 77.3 0.0 1.3e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase p450 PF00067.17 EPS26134.1 - 1.1e-43 149.3 0.0 1.5e-43 149.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.23 EPS26135.1 - 3.7e-156 519.6 0.0 2.7e-77 259.9 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EPS26135.1 - 6.3e-64 215.6 0.0 2.6e-30 105.3 0.0 3.3 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.20 EPS26135.1 - 2.5e-23 82.0 0.0 2.2e-13 50.2 0.0 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EPS26135.1 - 4.7e-08 33.8 0.0 0.012 16.5 0.0 3.2 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain PPDK_N PF01326.14 EPS26136.1 - 3.2e-88 295.9 0.0 5.1e-88 295.2 0.0 1.2 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers_C PF02896.13 EPS26136.1 - 4.2e-60 203.1 0.0 6.4e-60 202.5 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilizers PF00391.18 EPS26136.1 - 3.8e-23 80.8 0.2 8.3e-23 79.7 0.1 1.6 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain Methyltransf_25 PF13649.1 EPS26137.1 - 0.00026 21.3 0.2 0.0036 17.6 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPS26137.1 - 0.0038 16.9 0.0 0.027 14.1 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPS26137.1 - 0.06 13.8 0.0 0.15 12.5 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain p450 PF00067.17 EPS26138.1 - 1.5e-63 214.9 0.0 1.9e-63 214.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1731 PF08338.6 EPS26138.1 - 0.0028 17.1 0.2 0.013 14.9 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1731) Terpene_synth_C PF03936.11 EPS26139.1 - 2.7e-08 33.3 1.0 7e-08 32.0 0.7 1.7 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain p450 PF00067.17 EPS26140.1 - 2.8e-43 148.0 0.0 6.5e-43 146.9 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.23 EPS26141.1 - 1.1e-83 281.0 0.0 1.8e-83 280.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EPS26141.1 - 9.6e-28 96.8 0.0 1.6e-24 86.2 0.0 2.7 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.20 EPS26141.1 - 4.3e-07 30.1 0.1 2.1e-06 27.9 0.0 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EPS26141.1 - 7.2e-07 30.0 0.0 2.6e-06 28.2 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ldh_1_N PF00056.18 EPS26142.1 - 1.3e-22 80.1 0.1 1.9e-22 79.6 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EPS26142.1 - 7.3e-17 61.6 0.0 2.1e-16 60.1 0.0 1.8 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_4 PF02056.11 EPS26142.1 - 0.001 18.4 0.1 0.0029 16.9 0.0 1.7 1 1 1 2 2 2 1 Family 4 glycosyl hydrolase F420_oxidored PF03807.12 EPS26142.1 - 0.0019 18.5 0.2 0.0096 16.3 0.1 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 EPS26142.1 - 0.006 16.5 0.7 0.012 15.6 0.5 1.5 1 0 0 1 1 1 1 TrkA-N domain ThiF PF00899.16 EPS26142.1 - 0.18 11.6 0.9 0.42 10.4 0.4 1.7 1 1 0 1 1 1 0 ThiF family NAD_Gly3P_dh_N PF01210.18 EPS26142.1 - 0.22 11.2 1.0 0.74 9.5 0.2 2.2 1 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AdoHcyase_NAD PF00670.16 EPS26142.1 - 0.41 10.4 2.2 2.6 7.8 0.4 2.6 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EPS26144.1 - 9.2e-51 171.5 0.0 1.6e-50 170.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EPS26144.1 - 2.5e-15 56.1 0.0 3.5e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EPS26144.1 - 0.0042 16.9 0.0 0.024 14.4 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.17 EPS26144.1 - 0.11 13.0 0.0 14 6.2 0.0 2.9 3 0 0 3 3 3 0 Oxidoreductase family, NAD-binding Rossmann fold FH2 PF02181.18 EPS26146.1 - 9e-87 291.3 6.0 9e-87 291.3 4.2 1.8 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 EPS26146.1 - 1.5e-69 233.1 1.0 5.1e-69 231.4 0.0 2.4 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EPS26146.1 - 3.9e-53 179.8 0.4 1.3e-51 174.8 0.0 2.7 1 1 1 2 2 2 2 Diaphanous FH3 Domain TrmE_N PF10396.4 EPS26147.1 - 1.3e-36 125.0 0.0 2.9e-36 123.8 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 EPS26147.1 - 1.2e-24 86.5 0.3 4.5e-24 84.6 0.0 2.2 2 0 0 2 2 2 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 EPS26147.1 - 4.8e-18 65.2 0.0 8.6e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EPS26147.1 - 4.2e-05 23.0 0.0 0.0091 15.4 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EPS26147.1 - 8e-05 21.9 0.1 0.00038 19.7 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EPS26147.1 - 0.00016 21.5 0.0 0.00025 20.9 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Miro PF08477.8 EPS26147.1 - 0.0017 18.8 0.0 0.0044 17.4 0.0 1.8 1 1 0 1 1 1 1 Miro-like protein Glyco_hydro_3_C PF01915.17 EPS26147.1 - 0.0036 16.8 0.8 0.0059 16.1 0.6 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain AAA_24 PF13479.1 EPS26147.1 - 0.17 11.4 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Med6 PF04934.9 EPS26148.1 - 6e-41 139.2 0.0 8e-41 138.8 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component Lysine_decarbox PF03641.9 EPS26149.1 - 3.2e-29 101.4 0.2 1.4e-28 99.3 0.1 1.9 1 1 0 1 1 1 1 Possible lysine decarboxylase Proteasome PF00227.21 EPS26150.1 - 4.9e-50 169.4 0.1 6.2e-50 169.1 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EPS26150.1 - 2.8e-12 45.7 0.3 4.4e-12 45.0 0.2 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Vps55 PF04133.9 EPS26151.1 - 9.2e-48 160.9 5.3 1e-47 160.8 3.7 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 UPF0220 PF05255.6 EPS26153.1 - 9.6e-69 229.8 3.3 1.1e-68 229.7 2.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Fes1 PF08609.5 EPS26154.1 - 1.2e-33 115.4 5.5 2.2e-33 114.6 2.5 2.1 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 EPS26154.1 - 4.8e-10 39.5 1.9 4e-05 23.8 0.1 2.5 1 1 1 2 2 2 2 HEAT repeats HEAT_EZ PF13513.1 EPS26154.1 - 1.8e-06 28.2 0.4 0.00015 22.0 0.1 2.5 2 1 1 3 3 3 2 HEAT-like repeat Arm PF00514.18 EPS26154.1 - 1.7e-05 24.4 0.1 0.0012 18.6 0.0 2.5 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat HEAT PF02985.17 EPS26154.1 - 6.4e-05 22.6 0.1 0.019 15.0 0.0 2.6 2 0 0 2 2 2 1 HEAT repeat AAA_22 PF13401.1 EPS26154.1 - 0.022 14.8 0.0 0.033 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Adaptin_N PF01602.15 EPS26154.1 - 0.096 10.9 0.0 0.17 10.2 0.0 1.3 2 0 0 2 2 2 0 Adaptin N terminal region RICTOR_V PF14668.1 EPS26154.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, domain 5 Actin PF00022.14 EPS26156.1 - 1.3e-158 527.5 0.0 1.5e-158 527.4 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EPS26156.1 - 0.038 14.3 0.0 0.12 12.8 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) GARS_A PF01071.14 EPS26157.1 - 6.2e-81 270.6 0.0 9.3e-81 270.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 EPS26157.1 - 5.5e-35 119.8 0.6 2.8e-34 117.5 0.0 2.6 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 EPS26157.1 - 3.2e-31 108.4 0.0 8.5e-31 107.0 0.0 1.7 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 EPS26157.1 - 4.5e-27 94.0 0.1 1e-26 92.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 EPS26157.1 - 2.6e-15 56.4 1.9 2.6e-15 56.4 1.3 2.6 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 EPS26157.1 - 7.5e-09 35.5 0.0 2.2e-08 34.0 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EPS26157.1 - 2.9e-07 29.5 0.0 5.8e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EPS26157.1 - 0.00018 20.9 0.0 0.00033 20.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EPS26157.1 - 0.0027 17.0 0.0 0.0052 16.0 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.6 EPS26157.1 - 0.013 15.0 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 RimK-like ATP-grasp domain ATP-grasp_2 PF08442.5 EPS26157.1 - 0.021 14.1 0.0 0.052 12.9 0.0 1.5 2 0 0 2 2 2 0 ATP-grasp domain ATP-grasp_3 PF02655.9 EPS26157.1 - 0.028 14.3 0.0 0.14 12.0 0.0 2.2 2 1 0 2 2 2 0 ATP-grasp domain ATPgrasp_ST PF14397.1 EPS26157.1 - 0.27 10.2 0.0 0.73 8.8 0.0 1.6 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Pet127 PF08634.5 EPS26158.1 - 2.7e-122 407.1 1.2 3.8e-122 406.7 0.8 1.2 1 0 0 1 1 1 1 Mitochondrial protein Pet127 MFS_1 PF07690.11 EPS26159.1 - 1.7e-40 138.8 49.4 5.7e-40 137.1 34.2 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS26159.1 - 2.9e-13 49.2 28.8 1.8e-11 43.2 6.6 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter ATG22 PF11700.3 EPS26159.1 - 0.0032 16.0 16.4 0.0032 16.0 11.4 2.8 2 1 0 2 2 2 2 Vacuole effluxer Atg22 like DUF3169 PF11368.3 EPS26159.1 - 0.1 11.7 2.2 11 5.1 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) DUF4188 PF13826.1 EPS26160.1 - 3.4e-31 107.7 0.0 4.9e-31 107.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) LRR_6 PF13516.1 EPS26161.1 - 0.0082 16.1 0.5 2e+02 2.5 0.0 6.3 8 0 0 8 8 8 0 Leucine Rich repeat IGPD PF00475.13 EPS26163.1 - 6e-56 188.3 0.5 8.4e-56 187.8 0.4 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Gly_transf_sug PF04488.10 EPS26165.1 - 1e-19 70.7 0.0 1.8e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EPS26165.1 - 0.022 13.9 0.1 0.038 13.1 0.1 1.3 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Far-17a_AIG1 PF04750.9 EPS26165.1 - 0.14 11.3 3.0 0.18 10.9 0.2 2.2 2 0 0 2 2 2 0 FAR-17a/AIG1-like protein TcdA_TcdB PF12919.2 EPS26165.1 - 1.4 7.2 4.0 1.4 7.3 0.4 2.1 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain DER1 PF04511.10 EPS26168.1 - 4.3e-52 176.4 2.6 5e-52 176.2 1.8 1.0 1 0 0 1 1 1 1 Der1-like family Histone PF00125.19 EPS26169.1 - 7e-28 96.5 0.3 1e-27 96.0 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EPS26169.1 - 0.00073 19.6 0.1 0.0012 18.9 0.1 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 EPS26169.1 - 0.0066 15.7 1.0 0.0083 15.4 0.7 1.2 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T CBFD_NFYB_HMF PF00808.18 EPS26169.1 - 0.028 14.4 0.6 0.061 13.3 0.4 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TEBP_beta PF07404.6 EPS26169.1 - 3 6.9 5.6 2.3 7.2 3.0 1.5 2 0 0 2 2 2 0 Telomere-binding protein beta subunit (TEBP beta) Cohesin_load PF10345.4 EPS26170.1 - 4.9e-167 556.8 1.0 7e-167 556.3 0.7 1.1 1 0 0 1 1 1 1 Cohesin loading factor DUF3323 PF11796.3 EPS26170.1 - 0.065 12.5 4.4 0.019 14.3 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function N-terminus (DUF3323) HTH_WhiA PF02650.9 EPS26170.1 - 0.12 12.7 0.9 0.39 11.1 0.2 2.2 2 0 0 2 2 2 0 WhiA C-terminal HTH domain SpoVS PF04232.7 EPS26170.1 - 0.18 11.3 0.6 0.42 10.2 0.4 1.5 1 0 0 1 1 1 0 Stage V sporulation protein S (SpoVS) Abhydrolase_6 PF12697.2 EPS26171.1 - 3.4e-11 43.4 0.0 5.5e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPS26171.1 - 1.2e-10 41.3 0.0 2.2e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold MCM2_N PF12619.3 EPS26172.1 - 0.015 15.3 2.3 0.024 14.6 1.6 1.4 1 0 0 1 1 1 0 Mini-chromosome maintenance protein 2 Atg14 PF10186.4 EPS26172.1 - 2.5 6.9 6.3 2.7 6.8 4.4 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Complex1_LYR PF05347.10 EPS26173.1 - 1.3e-06 28.1 0.1 2.7e-06 27.0 0.1 1.6 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 EPS26173.1 - 2.2e-06 28.0 0.1 2.9e-06 27.6 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.1 EPS26173.1 - 1.4e-05 25.2 0.1 2.3e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Tetraspannin PF00335.15 EPS26174.1 - 0.0017 17.6 0.9 0.0017 17.6 0.6 2.2 2 0 0 2 2 2 1 Tetraspanin family ATP-grasp_2 PF08442.5 EPS26175.1 - 2.3e-56 190.4 0.0 3.1e-56 189.9 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 EPS26175.1 - 2.5e-17 62.9 0.4 1.6e-16 60.2 0.1 2.1 2 0 0 2 2 2 1 CoA-ligase ATP-grasp_5 PF13549.1 EPS26175.1 - 6.3e-10 38.6 0.1 5.5e-09 35.5 0.0 2.3 2 1 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EPS26175.1 - 0.00033 20.0 0.1 0.0007 18.9 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain GARS_A PF01071.14 EPS26175.1 - 0.00037 20.1 0.0 0.00088 18.8 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 EPS26175.1 - 0.0033 17.1 0.0 0.0067 16.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 EPS26175.1 - 0.0036 16.6 0.0 0.007 15.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain THF_DHG_CYH PF00763.18 EPS26175.1 - 0.098 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain F-box-like PF12937.2 EPS26176.1 - 0.0088 15.7 0.3 0.019 14.7 0.2 1.6 1 0 0 1 1 1 1 F-box-like Hydrophobin PF01185.13 EPS26177.1 - 0.85 10.1 6.9 4.1 7.9 1.2 2.2 1 1 1 2 2 2 0 Fungal hydrophobin Hydrophobin PF01185.13 EPS26178.1 - 0.57 10.6 6.4 38 4.8 4.5 2.2 1 1 0 1 1 1 0 Fungal hydrophobin TPP_enzyme_C PF02775.16 EPS26178.1 - 0.66 9.5 4.2 8.8 5.8 0.1 2.0 1 1 1 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain RNA_pol_L_2 PF13656.1 EPS26179.1 - 9.1e-29 98.7 0.0 1.2e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EPS26179.1 - 2e-12 46.0 0.0 2.6e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Tubulin_2 PF13809.1 EPS26180.1 - 0.023 13.6 0.2 0.027 13.4 0.1 1.1 1 0 0 1 1 1 0 Tubulin like YpjP PF14005.1 EPS26180.1 - 0.037 13.7 0.1 0.059 13.1 0.1 1.4 1 0 0 1 1 1 0 YpjP-like protein DUF697 PF05128.7 EPS26180.1 - 0.045 13.2 2.5 0.062 12.7 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF697) Flexi_CP PF00286.15 EPS26180.1 - 0.088 12.5 2.9 0.21 11.3 2.0 1.6 1 0 0 1 1 1 0 Viral coat protein Fib_alpha PF08702.5 EPS26182.1 - 0.017 15.2 2.8 0.059 13.5 0.1 2.4 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Med9 PF07544.8 EPS26182.1 - 0.02 14.6 2.8 1.1 9.0 0.2 3.3 4 0 0 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 TPR_MLP1_2 PF07926.7 EPS26182.1 - 0.032 13.9 3.7 0.57 9.9 0.1 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Baculo_PEP_C PF04513.7 EPS26182.1 - 0.1 12.4 2.0 2.4 7.9 0.1 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus RGCC PF15151.1 EPS26182.1 - 0.18 12.2 3.3 17 5.8 0.1 3.0 2 1 1 3 3 3 0 Response gene to complement 32 protein family ATG16 PF08614.6 EPS26182.1 - 0.38 10.5 3.3 0.29 10.9 0.1 2.4 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) HAD_2 PF13419.1 EPS26184.1 - 1.3e-05 25.4 0.0 0.009 16.2 0.0 2.1 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EPS26184.1 - 0.012 15.3 0.0 0.018 14.7 0.0 1.4 1 1 0 1 1 1 0 HAD-hyrolase-like Hydrolase PF00702.21 EPS26184.1 - 0.089 13.1 0.0 4.1 7.7 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase TPR_12 PF13424.1 EPS26185.1 - 8.1e-06 25.6 0.0 0.009 15.9 0.0 2.5 2 1 1 3 3 3 3 Tetratricopeptide repeat DUF3669 PF12417.3 EPS26187.1 - 0.014 15.0 0.0 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 Zinc finger protein Amidoligase_2 PF12224.3 EPS26189.1 - 4.8e-07 29.6 0.0 6.4e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Putative amidoligase enzyme AAA PF00004.24 EPS26191.1 - 5.3e-09 36.3 0.0 5e-08 33.2 0.0 2.2 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EPS26191.1 - 0.00074 20.3 0.0 0.0041 17.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain GSH_synthase PF03199.10 EPS26193.1 - 0.052 13.6 0.0 0.064 13.3 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic glutathione synthase RVT_1 PF00078.22 EPS26195.1 - 6.3e-29 100.8 0.0 9.3e-29 100.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EPS26195.1 - 0.0023 17.5 0.0 0.006 16.1 0.0 1.7 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase BTB PF00651.26 EPS26198.1 - 9.8e-13 48.0 0.1 2.2e-12 46.9 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain uDENN PF03456.13 EPS26199.1 - 0.13 12.2 0.2 0.33 10.9 0.1 1.6 1 0 0 1 1 1 0 uDENN domain Tetraspannin PF00335.15 EPS26200.1 - 2.5e-06 26.9 6.3 6.9e-06 25.4 4.4 1.7 1 1 0 1 1 1 1 Tetraspanin family TrbC PF04956.8 EPS26200.1 - 0.23 11.5 10.2 0.13 12.3 0.4 3.1 3 0 0 3 3 3 0 TrbC/VIRB2 family NfeD PF01957.13 EPS26200.1 - 1.1 9.3 7.8 0.66 10.0 2.8 2.3 2 1 0 2 2 2 0 NfeD-like C-terminal, partner-binding Strep_67kDa_ant PF06100.6 EPS26203.1 - 2.6e-113 379.0 0.0 3.1e-113 378.7 0.0 1.0 1 0 0 1 1 1 1 Streptococcal 67 kDa myosin-cross-reactive antigen like family NAD_binding_8 PF13450.1 EPS26203.1 - 0.12 12.4 0.0 6.8 6.7 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Endosulfine PF04667.12 EPS26204.1 - 3.4e-10 39.7 0.1 5.8e-10 38.9 0.0 1.5 1 1 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region DUF1640 PF07798.6 EPS26205.1 - 4e-13 49.7 5.0 4e-13 49.7 3.5 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF1640) LURAP PF14854.1 EPS26205.1 - 0.24 11.1 1.8 0.62 9.7 0.1 2.4 1 1 2 3 3 3 0 Leucine rich adaptor protein Seryl_tRNA_N PF02403.17 EPS26205.1 - 0.25 11.3 6.0 0.15 12.0 1.6 2.4 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain SF-assemblin PF06705.6 EPS26205.1 - 1.7 7.7 10.5 1.4 8.0 4.0 2.1 1 1 1 2 2 2 0 SF-assemblin/beta giardin ATP-synt_ab PF00006.20 EPS26208.1 - 2.8e-70 236.1 0.0 3.8e-70 235.7 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EPS26208.1 - 6.4e-25 87.8 0.4 1.7e-24 86.4 0.1 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EPS26208.1 - 9e-13 48.2 0.9 2.5e-12 46.8 0.6 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EPS26208.1 - 0.0031 17.3 0.9 0.0068 16.2 0.4 1.8 2 0 0 2 2 2 1 HAS barrel domain ATP-synt_ab PF00006.20 EPS26209.1 - 2e-69 233.4 0.0 3e-69 232.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.18 EPS26209.1 - 3.3e-13 49.6 0.8 7.1e-13 48.5 0.5 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain SBDS PF01172.13 EPS26211.1 - 2.1e-20 72.3 0.0 2.5e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein XkdN PF08890.6 EPS26211.1 - 0.036 13.8 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 Phage XkdN-like protein CorA PF01544.13 EPS26211.1 - 0.053 12.5 0.0 0.057 12.4 0.0 1.0 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Pex19 PF04614.7 EPS26212.1 - 0.00025 20.7 0.4 0.00031 20.4 0.3 1.0 1 0 0 1 1 1 1 Pex19 protein family HrpJ PF07201.6 EPS26212.1 - 0.02 14.8 2.3 0.028 14.4 1.6 1.2 1 0 0 1 1 1 0 HrpJ-like domain DUF4071 PF13281.1 EPS26212.1 - 0.027 13.3 0.2 0.03 13.1 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) IncA PF04156.9 EPS26212.1 - 0.051 13.1 3.5 0.058 12.9 2.4 1.1 1 0 0 1 1 1 0 IncA protein DUF3287 PF11690.3 EPS26212.1 - 0.078 13.0 2.0 0.095 12.7 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) ApoO PF09769.4 EPS26212.1 - 0.29 10.8 1.2 0.37 10.4 0.9 1.2 1 0 0 1 1 1 0 Apolipoprotein O MADF_DNA_bdg PF10545.4 EPS26212.1 - 0.38 10.9 3.6 0.73 10.0 2.5 1.6 1 1 0 1 1 1 0 Alcohol dehydrogenase transcription factor Myb/SANT-like ING PF12998.2 EPS26212.1 - 0.42 10.9 4.2 0.21 11.8 1.0 1.7 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding OmpH PF03938.9 EPS26212.1 - 1.6 8.6 4.0 2.1 8.2 2.8 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4316 PF14195.1 EPS26212.1 - 4.6 7.3 6.8 25 5.0 4.7 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4316) PRT_C PF08372.5 EPS26213.1 - 0.12 11.8 1.7 0.43 10.0 0.1 2.3 2 1 1 3 3 3 0 Plant phosphoribosyltransferase C-terminal DUF947 PF06102.7 EPS26217.1 - 4.8e-49 166.4 25.8 4.8e-49 166.4 17.8 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF947) NIF PF03031.13 EPS26218.1 - 9e-23 80.6 0.0 1.8e-22 79.7 0.0 1.5 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase EF1G PF00647.14 EPS26219.1 - 1.8e-44 149.7 0.0 3.4e-44 148.9 0.0 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 EPS26219.1 - 1.2e-13 50.8 0.0 3.2e-13 49.4 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EPS26219.1 - 2.2e-09 37.0 0.0 6.5e-09 35.5 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EPS26219.1 - 5.9e-07 29.5 0.0 1.4e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EPS26219.1 - 9.3e-07 29.2 0.2 1.9e-06 28.2 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EPS26219.1 - 1.3e-05 25.2 0.0 2.7e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EPS26219.1 - 0.1 12.5 0.0 0.32 11.0 0.0 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Ribosomal_60s PF00428.14 EPS26219.1 - 9 6.7 12.8 7.5 7.0 7.1 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein Ribosomal_S9 PF00380.14 EPS26220.1 - 7.8e-36 122.9 0.7 1.2e-35 122.3 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 EF-hand_1 PF00036.27 EPS26223.1 - 1.3e-27 92.9 11.2 2.9e-08 32.4 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EPS26223.1 - 2.1e-23 82.2 2.6 1.1e-12 47.8 0.4 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EPS26223.1 - 1.1e-20 71.5 6.5 2.8e-05 23.6 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EPS26223.1 - 4e-20 70.1 11.8 4.5e-07 28.9 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EPS26223.1 - 3.3e-15 55.4 11.9 1.8e-05 24.2 0.5 4.3 1 1 3 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EPS26223.1 - 1e-06 28.7 0.0 0.0015 18.5 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EPS26223.1 - 0.00013 21.6 7.5 0.36 10.5 0.2 4.0 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EPS26223.1 - 0.0052 16.6 0.0 0.33 10.8 0.0 2.9 2 1 1 3 3 3 1 EF-hand domain Anthrax-tox_M PF09156.5 EPS26223.1 - 0.031 13.3 0.5 0.072 12.1 0.1 1.6 2 0 0 2 2 2 0 Anthrax toxin lethal factor, middle domain EPL1 PF10513.4 EPS26224.1 - 1.2e-32 113.3 1.3 1.2e-32 113.3 0.9 3.2 3 0 0 3 3 3 1 Enhancer of polycomb-like SpecificRecomb PF10136.4 EPS26224.1 - 0.38 8.7 3.2 0.61 8.0 2.2 1.2 1 0 0 1 1 1 0 Site-specific recombinase SET PF00856.23 EPS26225.1 - 5.5e-17 62.5 0.0 8.5e-16 58.6 0.0 2.5 2 1 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.6 EPS26225.1 - 3e-06 27.1 0.1 6.2e-06 26.1 0.1 1.6 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Peptidase_M22 PF00814.20 EPS26226.1 - 2.8e-86 289.3 0.0 3.3e-86 289.1 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family AMPKBI PF04739.10 EPS26227.1 - 2.9e-29 100.8 0.6 2.9e-29 100.8 0.4 1.9 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain DUF4399 PF14347.1 EPS26227.1 - 0.007 16.3 0.0 0.021 14.8 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4399) Phage_Coat_Gp8 PF05371.7 EPS26228.1 - 0.86 9.2 3.9 1.2 8.8 0.1 2.7 2 1 1 3 3 3 0 Phage major coat protein, Gp8 Cupin_2 PF07883.6 EPS26229.1 - 4.8e-10 38.8 0.0 6.7e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 Cupin domain CDO_I PF05995.7 EPS26229.1 - 0.015 14.4 0.0 0.024 13.8 0.0 1.3 1 1 0 1 1 1 0 Cysteine dioxygenase type I CENP-C_C PF11699.3 EPS26229.1 - 0.022 14.7 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 Mif2/CENP-C like DUF4437 PF14499.1 EPS26229.1 - 0.067 12.0 0.0 0.09 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) ADH_zinc_N_2 PF13602.1 EPS26230.1 - 9.3e-20 71.8 0.1 1.7e-19 70.9 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EPS26230.1 - 2.5e-13 49.7 0.0 4.5e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EPS26230.1 - 1.7e-05 24.8 0.1 2.7e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EPS26230.1 - 9e-05 22.7 0.1 0.00015 22.0 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain ADH_N PF08240.7 EPS26230.1 - 0.00012 21.8 0.0 0.0026 17.5 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DapB_N PF01113.15 EPS26230.1 - 0.00061 19.7 0.0 0.001 18.9 0.0 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.12 EPS26230.1 - 0.011 14.6 0.1 0.052 12.4 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain TrkA_N PF02254.13 EPS26230.1 - 0.037 14.0 0.1 0.077 12.9 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Epimerase PF01370.16 EPS26230.1 - 0.074 12.4 0.1 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Fungal_trans_2 PF11951.3 EPS26231.1 - 4.9e-05 22.0 0.2 7.1e-05 21.5 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS26231.1 - 0.0014 18.5 11.4 0.0024 17.7 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_18 PF00704.23 EPS26232.1 - 6.3e-18 65.3 2.9 1.6e-16 60.7 0.3 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 COesterase PF00135.23 EPS26233.1 - 8.9e-61 206.1 0.0 1.3e-55 189.1 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EPS26233.1 - 2.4e-07 30.5 0.0 4.3e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EPS26233.1 - 0.0024 17.4 0.0 0.0051 16.3 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPS26233.1 - 0.013 15.2 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPS26233.1 - 0.02 14.7 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family mRNA_cap_enzyme PF01331.14 EPS26234.1 - 4.4e-52 176.5 0.5 5.9e-52 176.1 0.4 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 EPS26234.1 - 7e-22 77.7 0.0 1.4e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 EPS26234.1 - 2.2e-08 33.7 0.3 1.2e-06 28.1 0.2 2.4 1 1 0 1 1 1 1 ATP dependent DNA ligase domain SCA7 PF08313.7 EPS26236.1 - 4e-34 116.0 2.0 1.2e-33 114.5 1.4 1.8 1 0 0 1 1 1 1 SCA7, zinc-binding domain PhnG PF06754.7 EPS26236.1 - 0.027 14.0 1.1 0.58 9.7 0.0 2.6 3 0 0 3 3 3 0 Phosphonate metabolism protein PhnG CDC45 PF02724.9 EPS26236.1 - 3.9 5.3 10.7 5.5 4.8 7.4 1.2 1 0 0 1 1 1 0 CDC45-like protein ketoacyl-synt PF00109.21 EPS26237.1 - 6e-58 196.3 1.4 6e-58 196.3 1.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EPS26237.1 - 2.2e-32 111.4 3.3 3.2e-32 110.8 1.1 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EPS26237.1 - 1.3e-05 24.3 0.6 5.6e-05 22.2 0.1 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EPS26237.1 - 0.011 15.1 2.9 0.021 14.2 0.2 2.6 3 0 0 3 3 3 0 Thiolase, C-terminal domain Arginase PF00491.16 EPS26238.1 - 7e-91 304.3 0.0 8.4e-91 304.0 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EPS26238.1 - 0.0015 18.7 0.1 0.003 17.7 0.0 1.4 1 0 0 1 1 1 1 UPF0489 domain Ras PF00071.17 EPS26239.1 - 2e-52 176.8 0.0 2.3e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPS26239.1 - 6e-16 59.0 0.0 9e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPS26239.1 - 1.2e-06 27.9 0.0 1.6e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gag_spuma PF03276.9 EPS26240.1 - 2.8 6.1 7.9 3.1 6.0 5.5 1.0 1 0 0 1 1 1 0 Spumavirus gag protein MFS_1 PF07690.11 EPS26241.1 - 2.1e-19 69.4 44.4 1.2e-18 66.9 29.1 2.6 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EPS26241.1 - 0.00073 19.2 4.6 0.00073 19.2 3.2 2.7 2 0 0 2 2 2 1 MFS_1 like family Fst_toxin PF13955.1 EPS26241.1 - 0.4 10.4 2.8 1.2 8.9 2.0 1.9 1 0 0 1 1 1 0 Toxin Fst, type I toxin-antitoxin system DUF1349 PF07081.6 EPS26242.1 - 5.8e-27 94.2 0.0 7.4e-27 93.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) DUF2753 PF10952.3 EPS26247.1 - 0.094 12.6 0.0 0.094 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2753) Pyridoxal_deC PF00282.14 EPS26248.1 - 4.3e-50 170.2 0.0 5.9e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EPS26248.1 - 4.8e-05 22.2 0.0 7.7e-05 21.5 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EPS26248.1 - 8.8e-05 21.6 0.0 0.00015 20.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II AMP-binding PF00501.23 EPS26249.1 - 3.8e-84 282.4 0.0 5.1e-84 282.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EPS26249.1 - 6.9e-36 123.4 0.0 1.2e-35 122.5 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding_C PF13193.1 EPS26249.1 - 1.5e-08 35.4 0.0 4.5e-08 33.9 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Epimerase PF01370.16 EPS26249.1 - 0.00026 20.5 0.0 0.0024 17.3 0.0 2.4 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family Surf_Ag_VNR PF07244.10 EPS26249.1 - 0.007 16.7 0.1 0.025 14.9 0.0 2.0 2 0 0 2 2 2 1 Surface antigen variable number repeat GH3 PF03321.8 EPS26249.1 - 0.16 10.4 0.0 0.25 9.8 0.0 1.2 1 0 0 1 1 1 0 GH3 auxin-responsive promoter adh_short PF00106.20 EPS26250.1 - 4.9e-16 59.0 0.6 3.8e-15 56.2 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EPS26250.1 - 3.4e-09 36.6 0.0 6.4e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPS26250.1 - 0.00028 20.3 0.1 0.00071 19.0 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EPS26250.1 - 0.00044 19.2 0.0 0.00084 18.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein SPACA7 PF15307.1 EPS26250.1 - 0.052 13.6 0.0 0.25 11.4 0.0 1.9 2 0 0 2 2 2 0 Sperm acrosome-associated protein 7 CoA_transf_3 PF02515.12 EPS26250.1 - 0.084 12.1 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 CoA-transferase family III MFS_1 PF07690.11 EPS26251.1 - 1e-31 109.9 87.4 5.1e-29 101.0 45.3 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS26251.1 - 0.00039 19.1 42.5 0.046 12.3 11.1 3.1 2 2 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 EPS26251.1 - 0.19 10.0 48.4 0.0058 15.0 5.3 4.2 1 1 2 4 4 4 0 MFS/sugar transport protein DIT1_PvcA PF05141.7 EPS26252.1 - 1.2e-69 234.7 0.0 1e-68 231.7 0.0 2.0 1 1 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.11 EPS26252.1 - 1.8e-33 116.2 0.2 2.7e-33 115.7 0.1 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Hydrolase_6 PF13344.1 EPS26253.1 - 9.5e-31 105.6 0.0 1.6e-30 104.9 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EPS26253.1 - 9.4e-16 57.2 0.0 1.8e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EPS26253.1 - 1.7e-07 31.8 0.0 4.6e-07 30.4 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EPS26253.1 - 3.1e-06 27.5 0.0 0.032 14.4 0.0 2.4 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PNK3P PF08645.6 EPS26253.1 - 0.062 12.7 0.0 0.71 9.3 0.0 2.2 2 0 0 2 2 2 0 Polynucleotide kinase 3 phosphatase Peripla_BP_4 PF13407.1 EPS26253.1 - 0.066 12.5 0.1 0.32 10.2 0.0 2.1 2 1 1 3 3 3 0 Periplasmic binding protein domain Acid_phosphat_B PF03767.9 EPS26253.1 - 0.13 11.6 0.0 0.33 10.3 0.0 1.6 2 0 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) DUF4066 PF13278.1 EPS26255.1 - 4e-23 81.5 0.0 7.2e-23 80.6 0.0 1.4 1 1 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EPS26255.1 - 9.6e-15 54.3 0.0 1.3e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family Serglycin PF04360.7 EPS26256.1 - 0.027 14.2 1.7 0.027 14.2 1.2 1.8 2 0 0 2 2 2 0 Serglycin DIT1_PvcA PF05141.7 EPS26257.1 - 3e-86 289.1 0.0 4.4e-86 288.6 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein GST_N PF02798.15 EPS26258.1 - 2.8e-12 46.6 0.0 6.3e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EPS26258.1 - 8.2e-10 38.5 0.0 2.1e-09 37.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EPS26258.1 - 1.8e-09 37.6 0.0 3.5e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EPS26258.1 - 3e-09 36.6 0.0 5.6e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EPS26258.1 - 9e-09 35.2 0.0 1.8e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EPS26258.1 - 0.014 15.8 0.0 0.022 15.1 0.0 1.4 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 EPS26258.1 - 0.11 12.8 0.0 0.25 11.7 0.0 1.6 2 0 0 2 2 2 0 MetRS-N binding domain Trp_halogenase PF04820.9 EPS26259.1 - 3.9e-13 48.8 0.1 1.1e-08 34.1 0.0 3.2 2 1 0 3 3 3 3 Tryptophan halogenase DAO PF01266.19 EPS26259.1 - 0.001 18.0 0.2 0.002 17.1 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EPS26259.1 - 0.0013 17.9 0.0 0.002 17.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase zf-ribbon_3 PF13248.1 EPS26259.1 - 0.0075 15.4 2.6 0.019 14.1 1.8 1.7 1 0 0 1 1 1 1 zinc-ribbon domain HI0933_like PF03486.9 EPS26259.1 - 0.018 13.5 0.2 0.025 13.0 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_8 PF13450.1 EPS26259.1 - 0.018 15.0 0.0 0.061 13.3 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EPS26259.1 - 0.044 12.7 0.2 0.71 8.7 0.0 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein Zn_clus PF00172.13 EPS26260.1 - 2.3e-05 24.1 8.4 4.1e-05 23.3 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 EPS26262.1 - 2.2e-57 194.6 0.0 2.9e-57 194.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1910 PF08928.5 EPS26263.1 - 0.0012 18.9 0.3 0.012 15.6 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1910) DUF3357 PF11837.3 EPS26263.1 - 1.3 8.9 3.8 21 5.0 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) COesterase PF00135.23 EPS26264.1 - 4.5e-97 325.9 0.0 6.2e-97 325.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EPS26264.1 - 4.4e-06 26.4 0.3 3.8e-05 23.3 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Alpha-amylase PF00128.19 EPS26265.1 - 2.7e-74 250.4 0.5 4.4e-74 249.7 0.4 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain CBM_20 PF00686.14 EPS26265.1 - 5.6e-33 112.4 0.3 1.5e-32 111.0 0.2 1.8 1 0 0 1 1 1 1 Starch binding domain DUF1966 PF09260.6 EPS26265.1 - 5.9e-32 109.5 1.4 1.9e-31 107.9 0.9 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Aminotran_5 PF00266.14 EPS26265.1 - 0.049 12.3 0.1 0.11 11.1 0.0 1.6 2 0 0 2 2 2 0 Aminotransferase class-V DUF965 PF06135.7 EPS26265.1 - 0.17 11.9 0.3 12 6.0 0.0 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF965) ADH_N PF08240.7 EPS26266.1 - 3.4e-21 75.0 6.9 5.5e-21 74.3 4.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPS26266.1 - 5.7e-19 67.9 0.0 8.8e-19 67.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPS26266.1 - 6.8e-09 36.6 0.0 1.6e-08 35.4 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 EPS26266.1 - 0.0022 17.9 0.0 0.0036 17.2 0.0 1.2 1 0 0 1 1 1 1 TrkA-N domain 2-Hacid_dh_C PF02826.14 EPS26266.1 - 0.0065 15.6 0.2 0.011 14.9 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Grp1_Fun34_YaaH PF01184.14 EPS26268.1 - 1.5e-15 57.0 17.8 1.9e-15 56.7 12.4 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family adh_short PF00106.20 EPS26269.1 - 8.8e-28 97.3 0.0 1.2e-27 96.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPS26269.1 - 2.8e-13 50.1 0.0 3.9e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPS26269.1 - 2.2e-12 47.0 0.0 3.5e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPS26269.1 - 5.2e-07 29.3 0.0 1.7e-06 27.6 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EPS26269.1 - 8.6e-05 22.6 0.0 0.00011 22.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EPS26269.1 - 0.0002 20.3 0.0 0.00029 19.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain MGS PF02142.17 EPS26269.1 - 0.083 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 MGS-like domain Eno-Rase_NADH_b PF12242.3 EPS26269.1 - 0.085 12.6 0.1 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 EPS26269.1 - 0.096 11.8 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NmrA PF05368.8 EPS26269.1 - 0.11 11.7 0.1 0.25 10.5 0.0 1.5 2 0 0 2 2 2 0 NmrA-like family ADH_zinc_N_2 PF13602.1 EPS26269.1 - 0.12 13.2 0.0 0.28 12.0 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DUF2406 PF10295.4 EPS26270.1 - 5.2e-22 78.1 1.1 7.9e-22 77.5 0.1 1.7 2 0 0 2 2 2 1 Uncharacterised protein (DUF2406) Acyl-CoA_dh_1 PF00441.19 EPS26271.1 - 2.2e-33 115.4 1.6 4.6e-33 114.4 1.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EPS26271.1 - 2.8e-17 63.3 0.1 7.4e-17 61.9 0.1 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EPS26271.1 - 1.1e-15 57.9 1.5 1.1e-15 57.9 1.1 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EPS26271.1 - 9.4e-13 47.4 0.1 1.9e-12 46.4 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain CoA_transf_3 PF02515.12 EPS26272.1 - 7.5e-65 217.7 0.0 1.1e-64 217.2 0.0 1.3 1 0 0 1 1 1 1 CoA-transferase family III CbiG_N PF11760.3 EPS26272.1 - 0.073 12.7 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Cobalamin synthesis G N-terminal Pyr_redox PF00070.22 EPS26273.1 - 1.7e-12 47.5 0.6 2.8e-11 43.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPS26273.1 - 1.1e-10 41.7 0.1 0.0018 18.1 0.0 4.1 1 1 2 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPS26273.1 - 1.9e-08 34.6 0.2 0.00086 19.4 0.1 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EPS26273.1 - 1e-06 27.9 0.1 3e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EPS26273.1 - 3e-06 26.3 0.0 0.013 14.4 0.0 3.7 4 0 0 4 4 4 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 EPS26273.1 - 1e-05 25.6 0.0 0.00022 21.4 0.0 2.6 3 0 0 3 3 3 1 Putative NAD(P)-binding NAD_binding_9 PF13454.1 EPS26273.1 - 0.00045 20.0 0.1 3.3 7.4 0.0 3.5 2 1 1 3 3 3 1 FAD-NAD(P)-binding TrkA_N PF02254.13 EPS26273.1 - 0.0032 17.4 0.7 0.17 11.8 0.0 3.1 3 0 0 3 3 3 1 TrkA-N domain NAD_binding_8 PF13450.1 EPS26273.1 - 0.0074 16.2 0.0 0.25 11.3 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EPS26273.1 - 0.033 13.1 0.1 0.71 8.7 0.0 2.7 2 1 1 3 3 3 0 Lycopene cyclase protein Trp_halogenase PF04820.9 EPS26273.1 - 0.036 12.6 0.0 0.14 10.7 0.0 2.0 3 0 0 3 3 3 0 Tryptophan halogenase ApbA PF02558.11 EPS26273.1 - 0.045 13.1 0.1 0.42 10.0 0.0 2.7 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA COX1 PF00115.15 EPS26274.1 - 0.04 12.5 0.7 0.047 12.3 0.5 1.0 1 0 0 1 1 1 0 Cytochrome C and Quinol oxidase polypeptide I AA_permease PF00324.16 EPS26275.1 - 2.1e-87 293.4 40.2 2.6e-87 293.1 27.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPS26275.1 - 8e-23 80.6 43.9 9.6e-23 80.3 30.5 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 EPS26275.1 - 6 6.6 13.4 0.051 13.3 0.5 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF1772) AMP-binding PF00501.23 EPS26276.1 - 0 1429.3 1.8 8.3e-86 287.9 0.0 7.3 6 1 0 6 6 6 6 AMP-binding enzyme Condensation PF00668.15 EPS26276.1 - 0 1021.8 2.0 1.9e-49 168.1 0.0 8.7 8 1 0 8 8 8 8 Condensation domain PP-binding PF00550.20 EPS26276.1 - 7.9e-77 253.4 11.6 5.9e-14 52.0 0.2 8.0 7 0 0 7 7 7 7 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EPS26276.1 - 1.3e-28 99.7 2.4 5.9e-05 23.9 0.0 6.7 6 0 0 6 6 6 5 AMP-binding enzyme C-terminal domain GH3 PF03321.8 EPS26276.1 - 0.15 10.5 0.3 1.3e+02 0.9 0.1 4.6 5 0 0 5 5 5 0 GH3 auxin-responsive promoter TraY PF05509.6 EPS26276.1 - 0.44 10.3 0.7 5.8 6.7 0.2 2.5 2 0 0 2 2 2 0 TraY domain Pescadillo_N PF06732.6 EPS26276.1 - 1.4 8.1 0.3 27 3.8 0.1 2.7 3 0 0 3 3 3 0 Pescadillo N-terminus DUF619 PF04768.8 EPS26277.1 - 2.1e-14 53.2 0.1 6.8e-14 51.6 0.0 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF619) Ank PF00023.25 EPS26278.1 - 4.3e-25 86.2 7.3 9.2e-09 34.6 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 EPS26278.1 - 4.6e-22 78.1 2.0 1.2e-21 76.8 1.4 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPS26278.1 - 6e-20 71.2 0.9 6.7e-13 48.7 0.2 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPS26278.1 - 9.9e-16 56.2 2.4 1.7e-06 27.6 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 EPS26278.1 - 2.4e-15 56.2 2.7 1.4e-07 31.4 0.2 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Aminotran_4 PF01063.14 EPS26279.1 - 4.8e-26 91.6 0.0 5.8e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV p450 PF00067.17 EPS26280.1 - 1.3e-73 248.0 0.0 1.8e-73 247.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.21 EPS26281.1 - 3.1e-19 69.4 0.4 3.1e-19 69.4 0.3 2.5 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 EPS26281.1 - 7.4e-18 65.1 0.0 2.2e-17 63.6 0.0 1.9 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ketoacyl-synt_C PF02801.17 EPS26281.1 - 1.3e-13 50.8 0.0 7.3e-13 48.4 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EPS26281.1 - 0.0011 18.0 0.3 0.0029 16.6 0.2 1.6 1 1 0 1 1 1 1 Thiolase, N-terminal domain ABC_tran PF00005.22 EPS26282.1 - 1.5e-49 167.7 0.0 1.3e-28 99.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EPS26282.1 - 3.3e-37 128.3 29.9 6.5e-32 111.0 6.3 2.7 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_16 PF13191.1 EPS26282.1 - 2.5e-10 40.6 0.0 0.00031 20.7 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EPS26282.1 - 4.5e-09 36.5 0.9 0.00012 22.2 0.0 3.6 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EPS26282.1 - 1.2e-07 31.1 0.4 0.0035 16.8 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 EPS26282.1 - 2.1e-07 31.1 0.0 0.48 10.3 0.0 3.8 4 0 0 4 4 4 2 AAA domain SMC_N PF02463.14 EPS26282.1 - 4.6e-07 29.2 3.5 0.00061 19.0 0.6 3.9 2 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EPS26282.1 - 2.1e-06 27.0 0.3 0.017 14.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_33 PF13671.1 EPS26282.1 - 3.1e-06 27.1 0.2 0.0067 16.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EPS26282.1 - 8.1e-06 26.6 0.7 0.2 12.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EPS26282.1 - 2.7e-05 24.6 0.1 0.06 13.8 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_25 PF13481.1 EPS26282.1 - 0.00017 21.0 0.1 0.42 9.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EPS26282.1 - 0.00028 20.5 0.5 0.29 10.7 0.0 3.1 3 1 0 3 3 2 1 NACHT domain MobB PF03205.9 EPS26282.1 - 0.00032 20.4 1.0 0.74 9.5 0.1 2.4 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EPS26282.1 - 0.00044 20.1 0.1 0.53 10.2 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EPS26282.1 - 0.0013 18.2 0.7 0.47 9.8 0.1 3.0 3 0 0 3 3 3 1 FtsK/SpoIIIE family RNA_helicase PF00910.17 EPS26282.1 - 0.0015 18.6 0.1 3.3 7.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase DUF87 PF01935.12 EPS26282.1 - 0.0016 18.2 1.5 0.086 12.6 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 ATP-synt_ab PF00006.20 EPS26282.1 - 0.0025 17.3 0.6 1.6 8.2 0.0 3.1 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.1 EPS26282.1 - 0.0029 17.9 0.0 2.4 8.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EPS26282.1 - 0.0037 17.4 1.2 0.84 9.8 0.0 3.4 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EPS26282.1 - 0.0037 16.7 5.0 0.64 9.4 0.0 3.2 3 0 0 3 3 3 2 AAA-like domain AAA_23 PF13476.1 EPS26282.1 - 0.0053 17.1 0.6 1.5 9.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.12 EPS26282.1 - 0.0055 16.2 0.5 3 7.2 0.1 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_5 PF07728.9 EPS26282.1 - 0.0058 16.3 0.3 4.7 6.9 0.0 3.4 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 EPS26282.1 - 0.0068 16.2 0.1 5.2 7.0 0.0 3.0 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Septin PF00735.13 EPS26282.1 - 0.0071 15.4 0.9 1.5 7.7 0.1 2.3 2 0 0 2 2 2 1 Septin AAA_14 PF13173.1 EPS26282.1 - 0.012 15.4 0.1 2.4 8.0 0.0 2.9 3 0 0 3 3 2 0 AAA domain ArgK PF03308.11 EPS26282.1 - 0.015 14.1 0.3 0.21 10.3 0.0 2.2 2 0 0 2 2 2 0 ArgK protein Adeno_IVa2 PF02456.10 EPS26282.1 - 0.019 13.6 0.1 0.98 8.0 0.0 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein Viral_helicase1 PF01443.13 EPS26282.1 - 0.022 14.3 0.1 2.2 7.7 0.0 3.1 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase DUF815 PF05673.8 EPS26282.1 - 0.043 12.7 0.0 3.9 6.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Dynamin_N PF00350.18 EPS26282.1 - 0.046 13.5 0.5 1.1 9.0 0.0 2.3 2 0 0 2 2 2 0 Dynamin family Zeta_toxin PF06414.7 EPS26282.1 - 0.047 12.7 0.1 0.92 8.5 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.10 EPS26282.1 - 0.056 13.1 0.6 1.4 8.5 0.0 2.4 2 0 0 2 2 2 0 NTPase T2SE PF00437.15 EPS26282.1 - 0.066 12.1 1.9 3.4 6.4 0.0 2.5 3 0 0 3 3 2 0 Type II/IV secretion system protein Arch_ATPase PF01637.13 EPS26282.1 - 0.084 12.5 0.3 2.7 7.6 0.0 2.6 3 0 0 3 3 2 0 Archaeal ATPase Mg_chelatase PF01078.16 EPS26282.1 - 0.087 11.9 0.0 1.1 8.3 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.17 EPS26282.1 - 0.091 11.6 0.2 1.7 7.4 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Rad17 PF03215.10 EPS26282.1 - 0.095 11.3 0.5 0.4 9.3 0.0 1.9 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein cobW PF02492.14 EPS26282.1 - 0.12 11.7 2.6 3.4 7.0 0.1 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Sigma54_activat PF00158.21 EPS26282.1 - 0.16 11.4 0.0 7.8 5.9 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain UBA_e1_C PF09358.5 EPS26282.1 - 0.25 11.5 0.0 0.54 10.4 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-activating enzyme e1 C-terminal domain AAA_24 PF13479.1 EPS26282.1 - 0.28 10.7 0.3 19 4.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_PrkA PF08298.6 EPS26282.1 - 0.3 9.7 0.0 10 4.7 0.0 2.2 2 0 0 2 2 2 0 PrkA AAA domain 4HBT_2 PF13279.1 EPS26283.1 - 7.6e-08 32.8 0.0 1.3e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_transf_1 PF00698.16 EPS26284.1 - 2e-56 191.6 0.0 2.1e-54 185.0 0.0 3.3 3 1 0 3 3 3 1 Acyl transferase domain DUF1729 PF08354.5 EPS26284.1 - 1.1e-29 101.9 0.0 3.3e-29 100.4 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydratas PF01575.14 EPS26284.1 - 1.1e-27 95.7 0.0 3.6e-27 94.1 0.0 1.8 2 0 0 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EPS26284.1 - 4.4e-14 52.4 0.1 2.3e-13 50.0 0.0 2.2 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase NMO PF03060.10 EPS26284.1 - 0.088 11.9 0.1 2.6 7.1 0.0 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase RTA1 PF04479.8 EPS26285.1 - 1.3e-28 100.0 1.9 1.9e-28 99.5 1.3 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF1145 PF06611.7 EPS26285.1 - 0.0034 16.9 0.0 0.012 15.2 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1145) DUF3007 PF11460.3 EPS26285.1 - 0.14 12.2 4.6 1.5 8.9 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3007) PalH PF08733.5 EPS26285.1 - 3.8 6.2 11.5 8.2 5.1 0.1 2.1 1 1 1 2 2 2 0 PalH/RIM21 Ank_2 PF12796.2 EPS26286.1 - 7.6e-33 112.7 6.1 7.9e-14 51.7 0.2 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EPS26286.1 - 3.1e-29 99.3 13.9 1.4e-07 30.9 0.3 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 EPS26286.1 - 2.3e-25 88.0 8.5 1.1e-10 41.3 0.2 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EPS26286.1 - 5.7e-24 84.0 6.9 2.6e-11 43.7 0.1 3.7 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPS26286.1 - 1.8e-22 77.1 4.5 0.00035 20.5 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat bZIP_1 PF00170.16 EPS26286.1 - 0.022 14.6 5.4 0.038 13.9 3.8 1.3 1 0 0 1 1 1 0 bZIP transcription factor DUF605 PF04652.11 EPS26286.1 - 4.2 6.6 18.3 5.6 6.2 12.7 1.2 1 0 0 1 1 1 0 Vta1 like TSGP1 PF07771.6 EPS26287.1 - 0.3 10.9 3.4 0.47 10.3 2.4 1.2 1 0 0 1 1 1 0 Tick salivary peptide group 1 BLVR PF06375.6 EPS26287.1 - 1.2 8.9 10.3 1.7 8.4 7.2 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Peptidase_S49_N PF08496.5 EPS26287.1 - 2.7 7.7 5.8 3.9 7.2 4.0 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal HSDR_N_2 PF13588.1 EPS26290.1 - 0.082 12.7 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) DUF2199 PF09965.4 EPS26291.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2199) Pheromone PF08015.6 EPS26291.1 - 0.33 11.7 7.9 2.9 8.7 6.4 2.0 2 0 0 2 2 2 0 Fungal mating-type pheromone DUF3632 PF12311.3 EPS26292.1 - 3.4e-37 128.0 0.0 4.6e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Antifungal_prot PF11402.3 EPS26293.1 - 5.4e-19 68.1 9.7 6.6e-19 67.8 6.7 1.1 1 0 0 1 1 1 1 Antifungal protein MTHFR_C PF12225.3 EPS26293.1 - 0.0081 15.6 2.0 0.0094 15.4 1.4 1.1 1 0 0 1 1 1 1 Methylene-tetrahydrofolate reductase C terminal DUF3586 PF12131.3 EPS26293.1 - 0.088 12.8 1.2 0.13 12.3 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3586) Macin PF14865.1 EPS26293.1 - 1.7 8.8 6.7 1.1 9.3 0.3 2.1 1 1 1 2 2 2 0 Macin MFS_1 PF07690.11 EPS26294.1 - 4.3e-26 91.4 52.7 9.7e-18 63.9 17.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 EPS26295.1 - 2e-14 53.1 1.3 4.1e-14 52.0 0.9 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS26295.1 - 5.1e-09 35.9 10.2 1e-08 34.9 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 EPS26297.1 - 2.5e-50 171.5 0.0 3.9e-50 170.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Fungal_trans PF04082.13 EPS26298.1 - 2e-11 43.2 3.5 5.3e-11 41.8 2.4 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS26298.1 - 3e-05 23.8 13.1 5.3e-05 23.0 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.23 EPS26299.1 - 1.6e-84 283.7 0.0 2.7e-84 282.9 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EPS26299.1 - 4.2e-73 245.9 0.1 2e-72 243.7 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EPS26299.1 - 3e-54 184.5 0.1 7e-54 183.3 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EPS26299.1 - 5e-51 172.9 1.8 3.6e-50 170.1 0.1 2.9 3 0 0 3 3 2 1 KR domain Condensation PF00668.15 EPS26299.1 - 9.3e-50 169.1 1.6 2e-49 168.0 1.1 1.6 1 0 0 1 1 1 1 Condensation domain PS-DH PF14765.1 EPS26299.1 - 4.5e-48 163.9 2.1 7.8e-48 163.1 1.5 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EPS26299.1 - 5.5e-43 146.7 0.1 5.8e-41 140.1 0.0 3.1 3 0 0 3 3 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EPS26299.1 - 8.8e-29 99.7 0.0 2.3e-28 98.3 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 EPS26299.1 - 1.1e-25 89.9 0.0 1.9e-24 85.9 0.0 2.4 1 1 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.7 EPS26299.1 - 3.5e-20 72.3 0.0 1.1e-19 70.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EPS26299.1 - 7.9e-16 58.0 0.1 1.1e-06 28.7 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 EPS26299.1 - 5.2e-12 45.9 0.0 1.8e-11 44.1 0.0 2.0 1 0 0 1 1 1 1 HxxPF-repeated domain Epimerase PF01370.16 EPS26299.1 - 2.9e-11 43.2 0.0 2.8e-09 36.7 0.0 2.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Methyltransf_11 PF08241.7 EPS26299.1 - 1.4e-10 41.4 0.1 7.5e-10 39.1 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPS26299.1 - 4.6e-10 39.2 0.0 1.7e-09 37.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPS26299.1 - 2.1e-09 37.2 0.0 6e-09 35.8 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS26299.1 - 2.6e-09 37.6 0.0 2.7e-08 34.3 0.0 3.0 2 0 0 2 2 1 1 Methyltransferase domain 3Beta_HSD PF01073.14 EPS26299.1 - 6.7e-09 34.8 0.0 2e-07 29.9 0.0 2.2 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Thiolase_N PF00108.18 EPS26299.1 - 7e-06 25.2 0.1 1.6e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.13 EPS26299.1 - 1.7e-05 24.0 0.0 3.4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Glyco_hydro_42M PF08532.5 EPS26299.1 - 0.019 14.1 0.0 0.039 13.1 0.0 1.4 1 0 0 1 1 1 0 Beta-galactosidase trimerisation domain Methyltransf_16 PF10294.4 EPS26299.1 - 0.046 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase p450 PF00067.17 EPS26300.1 - 1.3e-35 122.8 0.0 1.6e-35 122.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EPS26301.1 - 6.6e-28 97.4 0.0 2.1e-27 95.7 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.21 EPS26302.1 - 6.6e-07 28.9 0.0 5.2e-06 26.0 0.0 2.4 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPS26302.1 - 1.2e-06 28.2 0.3 6.7e-05 22.6 0.0 2.8 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain MFS_1 PF07690.11 EPS26303.1 - 9.8e-25 87.0 58.0 2.3e-19 69.3 25.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS26303.1 - 0.14 10.6 43.3 1.3 7.5 12.4 3.1 2 1 0 2 2 2 0 Sugar (and other) transporter Zn_clus PF00172.13 EPS26304.1 - 0.2 11.5 15.8 0.41 10.6 11.0 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EPS26305.1 - 7.3e-41 140.0 48.2 6.8e-39 133.5 32.9 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPS26305.1 - 1.2e-13 50.1 23.8 5.4e-13 48.0 16.4 1.9 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) adh_short PF00106.20 EPS26306.1 - 3e-15 56.5 0.5 2.2e-14 53.7 0.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EPS26306.1 - 7.4e-07 29.0 0.2 1.2e-06 28.2 0.1 1.3 1 0 0 1 1 1 1 KR domain Polyketide_cyc PF03364.15 EPS26307.1 - 0.0001 22.3 0.6 0.00025 21.0 0.4 1.8 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 EPS26307.1 - 0.00018 21.6 3.9 0.00042 20.4 2.7 1.7 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport RXT2_N PF08595.6 EPS26309.1 - 0.18 11.6 1.5 0.18 11.5 1.0 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF4611 PF15387.1 EPS26309.1 - 0.2 11.7 2.8 0.23 11.6 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) CENP-B_dimeris PF09026.5 EPS26309.1 - 0.24 11.6 4.9 0.27 11.4 3.4 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 EPS26309.1 - 0.48 9.9 3.7 0.47 9.9 2.6 1.1 1 0 0 1 1 1 0 Nucleoplasmin DUF2457 PF10446.4 EPS26309.1 - 5.8 5.5 7.8 6.1 5.4 5.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Glycos_transf_1 PF00534.15 EPS26311.1 - 4.1e-10 39.3 0.0 7.5e-10 38.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EPS26311.1 - 1.6e-05 25.1 0.0 7.2e-05 22.9 0.0 2.1 1 1 1 2 2 2 1 Glycosyl transferases group 1 Enolase_C PF00113.17 EPS26312.1 - 2.6e-42 144.7 0.0 6.1e-41 140.3 0.0 2.0 1 1 0 1 1 1 1 Enolase, C-terminal TIM barrel domain TB PF00683.12 EPS26312.1 - 0.53 9.8 2.3 0.47 10.0 0.3 1.9 2 0 0 2 2 2 0 TB domain PSDC PF12588.3 EPS26313.1 - 3.1e-54 182.4 0.0 4.4e-54 181.9 0.0 1.2 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 EPS26313.1 - 4.1e-35 120.9 0.0 1.5e-34 119.0 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.1 EPS26313.1 - 0.0039 16.8 1.0 0.54 9.9 0.1 2.5 2 0 0 2 2 2 2 Biotin-lipoyl like Peptidase_M23 PF01551.17 EPS26313.1 - 0.089 12.8 0.4 0.22 11.6 0.0 1.9 2 0 0 2 2 2 0 Peptidase family M23 Biotin_lipoyl PF00364.17 EPS26313.1 - 0.09 12.4 0.6 0.2 11.2 0.1 1.8 2 0 0 2 2 2 0 Biotin-requiring enzyme PTS_EIIA_1 PF00358.15 EPS26313.1 - 0.14 11.6 0.3 0.27 10.8 0.2 1.4 1 0 0 1 1 1 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 AAA_17 PF13207.1 EPS26315.1 - 0.0045 17.8 0.1 0.027 15.3 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EPS26315.1 - 0.025 14.7 0.1 0.22 11.6 0.1 2.5 1 1 0 1 1 1 0 AAA domain B12-binding_2 PF02607.12 EPS26315.1 - 0.12 12.4 0.1 0.36 10.9 0.1 1.8 1 0 0 1 1 1 0 B12 binding domain AAA_16 PF13191.1 EPS26315.1 - 0.53 10.2 7.4 0.33 10.8 0.5 3.4 3 1 1 4 4 4 0 AAA ATPase domain Abhydrolase_6 PF12697.2 EPS26318.1 - 2.8e-26 92.8 5.0 4.4e-26 92.1 3.5 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPS26318.1 - 1.7e-14 53.8 0.1 1.9e-14 53.6 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPS26318.1 - 3.1e-11 43.2 0.0 3.7e-11 43.0 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EPS26318.1 - 6.5e-07 29.1 0.0 1.6e-06 27.8 0.0 1.7 1 1 0 1 1 1 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 EPS26318.1 - 0.014 14.9 0.0 0.02 14.4 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ndr PF03096.9 EPS26318.1 - 0.058 11.8 0.0 0.41 9.0 0.0 1.9 2 0 0 2 2 2 0 Ndr family Esterase_phd PF10503.4 EPS26318.1 - 0.073 12.3 0.4 0.19 10.9 0.0 1.8 2 0 0 2 2 2 0 Esterase PHB depolymerase Glyco_hydro_75 PF07335.6 EPS26319.1 - 7.9e-46 155.7 0.1 1.2e-45 155.2 0.1 1.3 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 Glyco_hydro_76 PF03663.9 EPS26320.1 - 9.8e-141 469.4 26.2 1.3e-140 469.0 18.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Cloacin_immun PF03513.9 EPS26320.1 - 0.0054 16.7 0.1 0.023 14.7 0.0 2.0 2 0 0 2 2 2 1 Cloacin immunity protein MFS_1 PF07690.11 EPS26321.1 - 1.9e-31 109.0 29.0 1.9e-31 109.0 20.1 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.13 EPS26322.1 - 8.7e-10 37.9 0.1 2.1e-09 36.6 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS26322.1 - 3e-08 33.4 13.0 6e-08 32.4 9.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC2_membrane PF01061.19 EPS26323.1 - 1.4e-82 275.9 53.7 1.3e-45 155.1 14.3 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EPS26323.1 - 2.5e-41 141.1 0.0 3.2e-19 69.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EPS26323.1 - 5.9e-26 90.1 0.2 1e-23 82.9 0.0 2.9 2 0 0 2 2 2 1 CDR ABC transporter AAA_21 PF13304.1 EPS26323.1 - 5.1e-09 36.5 0.0 0.08 12.8 0.0 3.4 3 0 0 3 3 3 3 AAA domain AAA_16 PF13191.1 EPS26323.1 - 2.6e-07 30.8 0.0 0.00019 21.4 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain ABC2_membrane_3 PF12698.2 EPS26323.1 - 2.7e-07 29.9 34.2 3.8e-05 22.8 7.8 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 EPS26323.1 - 8.1e-05 22.0 0.0 0.011 15.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EPS26323.1 - 0.00014 21.5 0.1 0.23 11.1 0.0 2.9 3 0 0 3 3 3 2 NACHT domain AAA_22 PF13401.1 EPS26323.1 - 0.00016 21.7 0.0 0.017 15.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EPS26323.1 - 0.00021 20.9 0.3 0.026 14.1 0.1 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 EPS26323.1 - 0.00021 20.4 0.0 0.0044 16.2 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_28 PF13521.1 EPS26323.1 - 0.00029 20.8 0.0 0.034 14.1 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EPS26323.1 - 0.00055 19.4 0.4 0.0075 15.7 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 EPS26323.1 - 0.00063 20.0 0.0 0.13 12.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EPS26323.1 - 0.00094 18.8 0.0 0.8 9.5 0.1 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EPS26323.1 - 0.0032 17.0 0.0 1.4 8.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EPS26323.1 - 0.0045 16.2 0.0 1.3 8.1 0.0 3.2 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EPS26323.1 - 0.0061 17.3 0.0 0.16 12.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EPS26323.1 - 0.0082 15.6 0.0 0.35 10.2 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 EPS26323.1 - 0.009 15.5 0.1 0.7 9.3 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.1 EPS26323.1 - 0.045 13.6 0.0 0.18 11.6 0.0 2.1 2 0 0 2 2 1 0 AAA domain SbcCD_C PF13558.1 EPS26323.1 - 0.049 13.5 0.0 0.33 10.8 0.0 2.2 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Miro PF08477.8 EPS26323.1 - 0.067 13.7 0.0 1.3 9.5 0.0 2.4 2 0 0 2 2 2 0 Miro-like protein AhpC-TSA PF00578.16 EPS26323.1 - 0.085 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA family Arch_ATPase PF01637.13 EPS26323.1 - 0.11 12.1 0.0 2.8 7.5 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase FtsK_SpoIIIE PF01580.13 EPS26323.1 - 0.12 11.8 0.0 15 5.0 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family T2SE PF00437.15 EPS26323.1 - 0.14 11.0 0.0 3.5 6.4 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_23 PF13476.1 EPS26323.1 - 0.15 12.3 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain NPP1 PF05630.6 EPS26324.1 - 5e-57 192.9 0.0 5.8e-57 192.7 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Glyco_hydro_61 PF03443.9 EPS26325.1 - 1.5e-84 283.1 0.0 2.2e-84 282.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EPS26325.1 - 4.6e-10 38.9 10.0 4.6e-10 38.9 6.9 2.0 2 0 0 2 2 2 1 Fungal cellulose binding domain AlaDh_PNT_C PF01262.16 EPS26325.1 - 0.12 11.9 0.0 0.12 11.9 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Asp PF00026.18 EPS26326.1 - 0.034 13.4 0.0 0.051 12.8 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic aspartyl protease PgaD PF13994.1 EPS26326.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 PgaD-like protein Glyco_transf_90 PF05686.7 EPS26328.1 - 1.9e-12 46.5 0.0 4e-12 45.5 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferase family 90 Na_H_Exchanger PF00999.16 EPS26329.1 - 8.9e-69 231.8 52.1 1.3e-68 231.3 36.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family CT47 PF15623.1 EPS26329.1 - 0.18 11.5 0.0 0.29 10.8 0.0 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 Sugar_tr PF00083.19 EPS26332.1 - 7.6e-81 271.9 21.5 9.5e-81 271.6 14.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS26332.1 - 2.1e-17 62.8 22.3 2.1e-17 62.8 15.5 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF3123 PF11321.3 EPS26332.1 - 0.027 14.7 0.0 0.062 13.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3123) DUF4646 PF15496.1 EPS26333.1 - 5.6e-17 61.9 0.0 1e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) Erf4 PF10256.4 EPS26333.1 - 0.002 18.0 0.0 0.0098 15.7 0.0 2.1 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family CoA_binding_3 PF13727.1 EPS26333.1 - 0.094 12.5 0.1 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 CoA-binding domain ISN1 PF06437.6 EPS26334.1 - 8.1e-192 637.4 0.0 9.1e-192 637.2 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase APH PF01636.18 EPS26334.1 - 0.046 13.4 0.1 0.1 12.2 0.1 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family PFK PF00365.15 EPS26335.1 - 1.7e-165 548.8 3.3 1.8e-118 394.5 0.7 2.1 2 0 0 2 2 2 2 Phosphofructokinase DUF4646 PF15496.1 EPS26335.1 - 0.027 14.5 0.0 0.067 13.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4646) Ribosomal_S9 PF00380.14 EPS26335.1 - 0.088 13.0 0.1 0.44 10.8 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein S9/S16 NAD_kinase PF01513.16 EPS26335.1 - 0.12 11.0 0.2 1 8.0 0.1 2.1 2 0 0 2 2 2 0 ATP-NAD kinase PAP2 PF01569.16 EPS26336.1 - 5e-24 84.4 1.7 5e-24 84.4 1.2 1.8 2 1 0 2 2 2 1 PAP2 superfamily TctB PF07331.6 EPS26336.1 - 0.22 11.1 8.0 0.69 9.5 0.7 2.5 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family DAO PF01266.19 EPS26337.1 - 1.5e-38 132.6 0.3 1.8e-38 132.3 0.2 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPS26337.1 - 4.7e-05 23.3 0.3 0.0002 21.3 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EPS26337.1 - 0.00071 19.3 0.2 0.012 15.4 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EPS26337.1 - 0.025 14.6 0.0 1.7 8.6 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPS26337.1 - 0.053 13.4 0.0 0.083 12.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Semialdhyde_dh PF01118.19 EPS26337.1 - 0.054 13.7 0.1 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Thi4 PF01946.12 EPS26337.1 - 0.062 12.3 0.1 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 EPS26337.1 - 0.14 11.0 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein MFS_1 PF07690.11 EPS26339.1 - 1.9e-35 122.2 28.7 1.9e-35 122.2 19.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Med17 PF10156.4 EPS26340.1 - 1.6e-110 369.6 0.0 2.1e-110 369.1 0.0 1.2 1 0 0 1 1 1 1 Subunit 17 of Mediator complex MgsA_C PF12002.3 EPS26340.1 - 0.032 13.9 0.0 0.059 13.0 0.0 1.3 1 0 0 1 1 1 0 MgsA AAA+ ATPase C terminal Glyco_hydro_1 PF00232.13 EPS26341.1 - 6.3e-71 238.9 0.1 7.9e-38 129.8 0.0 3.1 2 1 0 2 2 2 2 Glycosyl hydrolase family 1 Glyco_hydro_cc PF11790.3 EPS26341.1 - 0.001 18.5 0.1 0.0028 17.1 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core ADH_N PF08240.7 EPS26342.1 - 2.7e-25 88.2 0.0 6.7e-25 86.9 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPS26342.1 - 1.4e-17 63.4 0.8 2.5e-17 62.6 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPS26342.1 - 0.0013 19.5 0.1 0.0027 18.6 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Hydrolase_like PF13242.1 EPS26342.1 - 0.023 14.3 0.0 0.19 11.4 0.0 2.3 2 0 0 2 2 2 0 HAD-hyrolase-like Glyco_hydro_76 PF03663.9 EPS26343.1 - 1.3e-159 531.4 24.9 1.7e-159 531.1 17.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EPS26343.1 - 0.00079 18.5 10.3 0.11 11.4 0.0 3.3 1 1 2 3 3 3 3 Glycosyl Hydrolase Family 88 Glyco_hydro_47 PF01532.15 EPS26343.1 - 0.024 13.2 0.4 0.61 8.6 0.0 2.6 1 1 1 3 3 3 0 Glycosyl hydrolase family 47 Glyco_hydro_2 PF00703.16 EPS26344.1 - 2.5e-12 47.1 3.1 2.3e-11 44.1 0.0 3.1 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 EPS26344.1 - 4.5e-08 32.8 0.0 9.9e-08 31.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EPS26344.1 - 0.032 13.1 0.0 0.054 12.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Pox_G7 PF05503.7 EPS26345.1 - 0.079 11.5 0.1 0.13 10.8 0.0 1.4 1 0 0 1 1 1 0 Poxvirus G7-like COesterase PF00135.23 EPS26346.1 - 1.9e-91 307.3 0.0 2.2e-91 307.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EPS26346.1 - 4e-06 26.5 0.1 7.5e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EPS26346.1 - 0.00011 21.4 0.1 0.00018 20.7 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EPS26346.1 - 0.0015 18.2 0.1 0.0026 17.5 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF4316 PF14195.1 EPS26348.1 - 0.09 12.8 0.5 0.09 12.8 0.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4316) SelP_N PF04592.9 EPS26348.1 - 0.77 9.0 3.6 0.83 8.9 2.5 1.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DUF4650 PF15509.1 EPS26348.1 - 4.8 5.9 9.2 5.5 5.7 6.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4650) Dicty_REP PF05086.7 EPS26348.1 - 7.3 4.2 10.2 7.4 4.1 7.1 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Amidohydro_1 PF01979.15 EPS26349.1 - 7.5e-55 186.8 0.2 9.1e-55 186.6 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EPS26349.1 - 4.5e-14 52.4 0.2 2.7e-12 46.6 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EPS26349.1 - 1.4e-13 51.4 0.2 7.1e-12 45.9 0.1 2.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EPS26349.1 - 5.7e-08 32.4 0.0 1.6e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 EPS26349.1 - 0.0024 16.8 0.0 0.013 14.4 0.0 1.9 1 1 0 1 1 1 1 Adenosine/AMP deaminase Glyco_hydro_88 PF07470.8 EPS26350.1 - 1.4e-91 306.9 1.4 2.7e-91 306.0 1.0 1.4 1 1 1 2 2 2 1 Glycosyl Hydrolase Family 88 DUF1680 PF07944.7 EPS26350.1 - 0.00019 19.8 0.1 0.00024 19.5 0.1 1.2 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) MFS_1 PF07690.11 EPS26351.1 - 1.2e-30 106.4 20.9 1.7e-30 105.9 14.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily NfeD PF01957.13 EPS26351.1 - 0.15 12.1 0.0 0.15 12.1 0.0 3.1 2 2 2 4 4 4 0 NfeD-like C-terminal, partner-binding ESSS PF10183.4 EPS26351.1 - 4.1 7.8 8.0 0.93 9.9 0.1 3.0 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) NAD_binding_6 PF08030.7 EPS26352.1 - 7.3e-25 87.6 0.0 1.2e-24 86.9 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EPS26352.1 - 4e-19 68.9 11.2 4e-19 68.9 7.8 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EPS26352.1 - 2.4e-09 37.0 0.0 4.8e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EPS26352.1 - 6.1e-06 26.7 0.0 0.0011 19.5 0.0 2.3 1 1 0 2 2 2 1 Oxidoreductase NAD-binding domain Cytochrom_B_N PF00033.14 EPS26352.1 - 0.35 10.1 17.4 0.87 8.9 8.7 3.0 1 1 1 2 2 2 0 Cytochrome b(N-terminal)/b6/petB Ribonuclease_3 PF00636.21 EPS26353.1 - 4.4e-41 139.8 0.0 4.3e-20 72.2 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EPS26353.1 - 3.2e-28 98.2 0.1 1.1e-11 44.8 0.1 4.2 3 2 0 3 3 3 2 Ribonuclease-III-like Dicer_dimer PF03368.9 EPS26353.1 - 6.8e-24 83.4 0.0 1.6e-23 82.2 0.0 1.7 1 0 0 1 1 1 1 Dicer dimerisation domain Helicase_C PF00271.26 EPS26353.1 - 5.5e-16 58.2 0.0 1.4e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPS26353.1 - 3.5e-15 55.8 0.0 7.9e-15 54.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EPS26353.1 - 2.8e-10 40.3 0.0 8.5e-10 38.7 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_11 PF13086.1 EPS26353.1 - 0.061 12.8 0.1 0.24 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF2296 PF10058.4 EPS26354.1 - 9.2e-20 70.1 0.1 1.5e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) DUF485 PF04341.7 EPS26354.1 - 0.053 13.2 0.2 0.079 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF485 PAT1 PF09770.4 EPS26354.1 - 0.3 9.2 17.6 0.42 8.7 12.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PHY PF00360.15 EPS26357.1 - 8.7e-30 103.2 0.0 1.7e-29 102.2 0.0 1.4 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.21 EPS26357.1 - 1.3e-17 63.5 0.0 2.8e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GAF PF01590.21 EPS26357.1 - 2.9e-16 59.9 0.1 1.3e-15 57.8 0.0 2.2 2 0 0 2 2 2 1 GAF domain Response_reg PF00072.19 EPS26357.1 - 4.6e-14 52.3 0.2 1.7e-13 50.5 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EPS26357.1 - 4.9e-12 45.6 0.4 1.7e-11 43.9 0.2 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.6 EPS26357.1 - 8e-08 32.7 0.0 3e-07 30.8 0.0 2.1 1 0 0 1 1 1 1 PAS fold HATPase_c_3 PF13589.1 EPS26357.1 - 0.16 11.6 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase bZIP_1 PF00170.16 EPS26361.1 - 2.8e-09 36.7 6.2 8.4e-09 35.2 4.3 1.7 1 1 0 1 1 1 1 bZIP transcription factor Glutaredoxin2_C PF04399.8 EPS26361.1 - 0.014 14.9 0.1 0.026 14.0 0.1 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain DUF3972 PF13118.1 EPS26361.1 - 0.047 13.7 0.3 0.13 12.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3972) Adeno_PIX PF03955.9 EPS26361.1 - 0.52 10.8 2.9 0.55 10.7 0.0 2.3 2 1 0 2 2 2 0 Adenovirus hexon-associated protein (IX) bZIP_2 PF07716.10 EPS26361.1 - 2 8.3 13.3 1.8 8.4 6.5 2.5 2 1 0 2 2 2 0 Basic region leucine zipper Not3 PF04065.10 EPS26361.1 - 3.1 6.9 6.7 2 7.6 0.3 2.1 2 0 0 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component Anoctamin PF04547.7 EPS26362.1 - 7.2e-126 420.4 1.1 9.2e-126 420.1 0.8 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Acetyltransf_1 PF00583.19 EPS26363.1 - 9.5e-14 51.2 0.0 1.5e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EPS26363.1 - 1.2e-07 31.3 0.0 2e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EPS26363.1 - 3.1e-06 27.2 0.0 4.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EPS26363.1 - 4.2e-05 23.7 0.0 5.8e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPS26363.1 - 0.00087 19.3 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EPS26363.1 - 0.0034 17.3 0.0 0.041 13.8 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain GRIP PF01465.15 EPS26364.1 - 1.6e-15 56.3 0.3 3.6e-15 55.1 0.2 1.7 1 0 0 1 1 1 1 GRIP domain MscS_porin PF12795.2 EPS26364.1 - 1.3e-06 27.8 126.8 0.0094 15.2 14.0 8.0 3 2 3 8 8 8 6 Mechanosensitive ion channel porin domain Reo_sigmaC PF04582.7 EPS26364.1 - 6.7e-06 25.5 57.2 0.031 13.4 5.0 6.4 3 2 4 7 7 7 4 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 EPS26364.1 - 3.2e-05 23.8 10.0 3.2e-05 23.8 7.0 10.1 3 2 6 9 9 9 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_13 PF13166.1 EPS26364.1 - 3.4e-05 22.5 105.3 0.041 12.3 13.7 5.2 1 1 3 4 4 4 3 AAA domain IncA PF04156.9 EPS26364.1 - 9.8e-05 22.0 153.7 0.02 14.4 11.1 8.8 2 2 5 7 7 7 3 IncA protein FH2 PF02181.18 EPS26364.1 - 0.00012 21.1 2.2 0.00012 21.1 1.5 7.5 2 2 4 7 7 7 1 Formin Homology 2 Domain HOOK PF05622.7 EPS26364.1 - 0.0005 18.0 21.6 0.0005 18.0 15.0 4.4 2 1 2 4 4 4 1 HOOK protein DUF1192 PF06698.6 EPS26364.1 - 0.0014 18.3 1.4 0.0014 18.3 0.9 10.6 9 1 2 11 11 9 1 Protein of unknown function (DUF1192) FliJ PF02050.11 EPS26364.1 - 0.0023 17.9 3.6 0.0023 17.9 2.5 9.2 3 2 8 11 11 11 4 Flagellar FliJ protein APG6 PF04111.7 EPS26364.1 - 0.0033 16.5 15.2 0.0033 16.5 10.6 7.5 2 2 5 7 7 7 3 Autophagy protein Apg6 Baculo_PEP_C PF04513.7 EPS26364.1 - 0.0081 15.9 41.7 4.2 7.2 1.5 7.6 4 2 2 6 6 6 1 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.6 EPS26364.1 - 0.0089 14.7 124.1 0.0055 15.4 9.3 7.6 2 2 6 8 8 8 5 Spc7 kinetochore protein Filament PF00038.16 EPS26364.1 - 0.0091 15.5 129.3 0.02 14.4 27.2 7.8 2 2 4 6 6 6 5 Intermediate filament protein GAS PF13851.1 EPS26364.1 - 0.017 14.3 130.3 0.1 11.7 6.6 9.5 2 2 8 10 10 10 0 Growth-arrest specific micro-tubule binding Tup_N PF08581.5 EPS26364.1 - 0.019 15.1 1.4 0.019 15.1 1.0 10.6 5 2 5 11 11 11 0 Tup N-terminal Myosin_tail_1 PF01576.14 EPS26364.1 - 0.02 12.6 153.5 0.2 9.3 28.8 4.4 2 1 1 3 3 3 0 Myosin tail TPR_MLP1_2 PF07926.7 EPS26364.1 - 0.033 13.9 141.7 0.013 15.2 10.6 10.1 2 2 7 10 10 9 0 TPR/MLP1/MLP2-like protein NPV_P10 PF05531.7 EPS26364.1 - 0.11 12.8 50.7 6.3 7.1 0.6 10.6 7 3 3 10 10 10 0 Nucleopolyhedrovirus P10 protein DUF869 PF05911.6 EPS26364.1 - 0.52 8.4 129.7 0.048 11.8 11.6 6.6 1 1 4 6 6 6 0 Plant protein of unknown function (DUF869) Fib_alpha PF08702.5 EPS26364.1 - 1.1 9.4 76.2 0.36 10.9 0.8 9.0 2 2 7 10 10 10 0 Fibrinogen alpha/beta chain family WEMBL PF05701.6 EPS26364.1 - 3.4 6.0 156.9 0.23 9.8 32.8 5.2 2 2 2 4 4 4 0 Weak chloroplast movement under blue light DUF948 PF06103.6 EPS26364.1 - 8.6 6.3 54.8 0.12 12.2 0.3 9.4 6 2 2 9 9 8 0 Bacterial protein of unknown function (DUF948) cNMP_binding PF00027.24 EPS26365.1 - 4e-37 125.9 0.0 2.3e-20 72.2 0.0 4.9 4 1 0 4 4 4 3 Cyclic nucleotide-binding domain Patatin PF01734.17 EPS26365.1 - 1.6e-18 67.4 5.2 1.9e-17 63.8 3.6 2.5 1 1 0 1 1 1 1 Patatin-like phospholipase CBM_1 PF00734.13 EPS26366.1 - 4.2e-12 45.4 12.7 9.4e-12 44.3 8.8 1.6 1 0 0 1 1 1 1 Fungal cellulose binding domain Lipase_GDSL_2 PF13472.1 EPS26366.1 - 4.7e-12 46.4 1.6 4.7e-12 46.4 1.1 1.7 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EPS26366.1 - 3.1e-09 36.9 0.2 5e-09 36.3 0.2 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF4397 PF14344.1 EPS26366.1 - 0.0029 17.9 0.1 0.0081 16.4 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4397) Lipase_GDSL_3 PF14606.1 EPS26366.1 - 0.03 14.0 0.0 0.055 13.1 0.0 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Toxin_7 PF05980.7 EPS26366.1 - 0.19 11.7 0.5 0.39 10.7 0.4 1.5 1 0 0 1 1 1 0 Toxin 7 MARVEL PF01284.18 EPS26367.1 - 1.6e-13 50.6 12.4 1.9e-13 50.4 8.6 1.1 1 0 0 1 1 1 1 Membrane-associating domain TMEMspv1-c74-12 PF11044.3 EPS26367.1 - 9.1 5.9 7.7 0.68 9.5 0.6 2.5 3 0 0 3 3 3 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Actin PF00022.14 EPS26368.1 - 8.6e-58 195.6 0.0 1.5e-30 105.9 0.0 2.2 2 0 0 2 2 2 2 Actin DUF3509 PF12021.3 EPS26368.1 - 0.025 14.3 0.4 0.23 11.2 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3509) DASH_Dad4 PF08650.5 EPS26369.1 - 7e-28 96.3 6.5 7.6e-28 96.2 4.5 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 GM_CSF PF01109.12 EPS26369.1 - 0.012 15.5 0.4 0.013 15.4 0.3 1.1 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor DASH_Dad1 PF08649.5 EPS26369.1 - 0.014 15.0 2.6 0.018 14.7 1.8 1.1 1 0 0 1 1 1 0 DASH complex subunit Dad1 DUF2443 PF10398.4 EPS26369.1 - 0.074 12.8 0.6 0.11 12.3 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2443) Kdo PF06293.9 EPS26369.1 - 0.1 11.6 0.1 0.12 11.4 0.1 1.0 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Biotin_carb_C PF02785.14 EPS26369.1 - 0.14 12.1 0.1 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 Biotin carboxylase C-terminal domain YL1_C PF08265.6 EPS26370.1 - 1.1e-14 53.6 0.1 2.2e-14 52.7 0.1 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Got1 PF04178.7 EPS26372.1 - 2.6e-19 69.4 12.9 3.1e-19 69.2 8.9 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family YrhK PF14145.1 EPS26372.1 - 0.47 10.1 9.9 0.13 11.9 3.5 2.2 2 0 0 2 2 2 0 YrhK-like protein SdpI PF13630.1 EPS26372.1 - 1.8 8.3 13.6 0.52 10.0 2.2 2.3 1 1 1 2 2 2 0 SdpI/YhfL protein family Profilin PF00235.14 EPS26373.1 - 4.9e-33 113.8 0.3 5.5e-33 113.6 0.2 1.0 1 0 0 1 1 1 1 Profilin ADP_ribosyl_GH PF03747.9 EPS26374.1 - 1.2e-58 199.2 0.4 1.4e-58 198.9 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase GH-E PF14410.1 EPS26374.1 - 0.019 15.0 0.1 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues Sec63 PF02889.11 EPS26377.1 - 6.5e-143 475.6 0.0 1.5e-93 313.5 0.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EPS26377.1 - 2.1e-55 186.8 0.4 7.9e-29 100.3 0.6 3.5 4 0 0 4 4 4 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EPS26377.1 - 5.3e-18 64.6 0.0 1.1e-07 31.6 0.0 3.0 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 EPS26377.1 - 1.2e-16 61.0 0.1 1.5e-07 31.4 0.0 2.7 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EPS26377.1 - 1.6e-07 31.5 0.0 0.029 14.4 0.0 3.3 2 2 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EPS26377.1 - 4.1e-06 26.4 0.4 0.011 15.4 0.0 3.3 3 0 0 3 3 3 2 Part of AAA domain SNF2_N PF00176.18 EPS26377.1 - 5.1e-05 22.2 0.5 0.13 11.0 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain FtsK_SpoIIIE PF01580.13 EPS26377.1 - 0.0024 17.3 0.0 0.51 9.7 0.0 3.1 3 0 0 3 3 3 1 FtsK/SpoIIIE family IstB_IS21 PF01695.12 EPS26377.1 - 0.0072 15.7 0.4 5.6 6.3 0.0 3.7 4 0 0 4 4 4 1 IstB-like ATP binding protein PhoH PF02562.11 EPS26377.1 - 0.009 15.2 0.1 2.5 7.2 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein DUF3824 PF12868.2 EPS26377.1 - 0.25 12.2 0.0 0.58 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Longin PF13774.1 EPS26378.1 - 1.4e-14 53.4 0.0 2.2e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EPS26378.1 - 1.5e-14 53.3 0.5 2.4e-14 52.7 0.3 1.3 1 0 0 1 1 1 1 Synaptobrevin Tbf5 PF06331.7 EPS26378.1 - 0.02 14.6 0.5 0.038 13.7 0.3 1.4 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 Metallophos PF00149.23 EPS26379.1 - 2e-18 66.5 0.0 5e-18 65.2 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 EPS26379.1 - 5.9e-13 48.6 0.8 1.2e-12 47.7 0.1 2.0 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 EPS26379.1 - 2.1e-06 26.6 0.2 4.3e-06 25.5 0.2 1.4 1 0 0 1 1 1 1 PhoD-like phosphatase Metallophos_2 PF12850.2 EPS26379.1 - 0.023 14.5 0.0 0.059 13.1 0.0 1.7 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Atg14 PF10186.4 EPS26380.1 - 0.023 13.6 0.2 0.036 13.0 0.1 1.3 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 AAA_13 PF13166.1 EPS26380.1 - 0.081 11.3 0.0 0.081 11.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain CCDC92 PF14916.1 EPS26380.1 - 0.1 12.2 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Coiled-coil domain of unknown function ATG16 PF08614.6 EPS26380.1 - 0.24 11.2 2.4 0.36 10.6 1.7 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Vps51 PF08700.6 EPS26380.1 - 0.24 11.2 1.3 7.4 6.4 0.1 2.4 2 1 0 2 2 2 0 Vps51/Vps67 2OG-FeII_Oxy_2 PF13532.1 EPS26382.1 - 1.6e-28 99.9 0.0 4e-28 98.5 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily FAM101 PF15068.1 EPS26382.1 - 0.019 14.4 0.4 0.019 14.4 0.2 1.8 2 0 0 2 2 2 0 FAM101 family DUF3431 PF11913.3 EPS26384.1 - 6.1e-81 271.1 0.0 7.4e-81 270.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Ras PF00071.17 EPS26385.1 - 3.3e-39 133.8 0.0 1.2e-36 125.5 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EPS26385.1 - 3.3e-17 63.0 0.0 5.1e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPS26385.1 - 9.4e-11 41.2 0.0 1.6e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EPS26385.1 - 0.00042 19.5 0.0 0.00055 19.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EPS26385.1 - 0.001 19.1 0.0 0.0021 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EPS26385.1 - 0.0014 18.5 0.0 0.0024 17.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EPS26385.1 - 0.0062 15.7 0.0 0.009 15.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 EPS26385.1 - 0.0063 16.5 0.0 0.032 14.2 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain PduV-EutP PF10662.4 EPS26385.1 - 0.008 15.6 0.0 0.16 11.4 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 EPS26385.1 - 0.029 14.3 0.1 0.082 12.8 0.1 1.8 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EPS26385.1 - 0.042 13.0 0.1 0.072 12.2 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 EPS26385.1 - 0.056 13.3 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EPS26385.1 - 0.067 13.0 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 EPS26385.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Dynamin family AAA_24 PF13479.1 EPS26385.1 - 0.15 11.6 0.0 0.25 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EPS26385.1 - 0.17 11.5 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Sugar_tr PF00083.19 EPS26386.1 - 7.2e-103 344.5 28.9 8.4e-103 344.3 20.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS26386.1 - 1e-24 86.9 44.0 3.1e-14 52.4 9.9 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily ELO PF01151.13 EPS26386.1 - 0.23 10.7 9.5 0.24 10.6 0.2 3.2 3 0 0 3 3 3 0 GNS1/SUR4 family Pox_A14 PF05767.7 EPS26386.1 - 0.3 11.0 0.0 0.3 11.0 0.0 3.5 4 0 0 4 4 4 0 Poxvirus virion envelope protein A14 FMN_dh PF01070.13 EPS26388.1 - 2.9e-123 411.2 0.1 3.7e-123 410.8 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EPS26388.1 - 1.4e-23 82.4 0.0 2.7e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EPS26388.1 - 5.5e-07 28.8 0.1 9e-07 28.1 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 EPS26388.1 - 1.8e-05 24.0 0.2 3e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EPS26388.1 - 0.00046 19.1 0.1 0.0014 17.5 0.0 1.8 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 EPS26388.1 - 0.0061 15.8 0.5 0.52 9.5 0.0 2.4 1 1 0 2 2 2 1 Histidine biosynthesis protein DUF561 PF04481.7 EPS26388.1 - 0.05 12.5 0.0 0.43 9.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF561) ThiG PF05690.9 EPS26388.1 - 0.11 11.5 0.1 7.7 5.5 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Brr6_like_C_C PF10104.4 EPS26389.1 - 5.9e-32 110.0 0.4 7.6e-32 109.6 0.3 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Nucleo_P87 PF07267.6 EPS26389.1 - 4.2 5.9 5.7 6.7 5.2 4.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Bud13 PF09736.4 EPS26390.1 - 1.7e-45 154.8 4.0 1.7e-45 154.8 2.8 2.4 3 1 0 3 3 3 1 Pre-mRNA-splicing factor of RES complex DNA_binding_1 PF01035.15 EPS26391.1 - 4.4e-21 74.4 0.1 6.2e-21 73.9 0.1 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Pkinase PF00069.20 EPS26392.1 - 8.5e-42 143.0 0.1 1.5e-24 86.5 0.0 2.8 2 2 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPS26392.1 - 1.3e-14 53.9 0.5 2.3e-10 39.9 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase YopE PF03545.8 EPS26392.1 - 0.048 13.5 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Yersinia virulence determinant (YopE) Metallophos_2 PF12850.2 EPS26393.1 - 4.2e-06 26.6 0.0 1e-05 25.4 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EPS26393.1 - 3.5e-05 23.2 4.3 0.00065 19.1 0.2 2.5 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase ELL PF10390.4 EPS26393.1 - 0.15 11.2 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL Ribonuclease PF00545.15 EPS26394.1 - 6.8e-19 67.7 1.0 9.1e-19 67.3 0.5 1.4 1 1 0 1 1 1 1 ribonuclease ATP-synt_E PF05680.7 EPS26395.1 - 2.2 8.2 6.0 1.3 9.0 3.0 1.5 1 1 0 1 1 1 0 ATP synthase E chain Na_Ca_ex PF01699.19 EPS26396.1 - 5.5e-40 136.2 29.8 2.3e-21 75.8 8.2 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Anoctamin PF04547.7 EPS26397.1 - 3.4e-99 332.5 5.0 4.5e-99 332.1 3.5 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Antimicrobial10 PF08105.6 EPS26397.1 - 0.053 13.1 0.3 5.9 6.5 0.0 2.6 1 1 1 2 2 2 0 Metchnikowin family DUF1212 PF06738.7 EPS26400.1 - 4.6e-57 192.6 9.2 3.9e-49 166.7 0.1 3.3 3 0 0 3 3 3 3 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EPS26400.1 - 7.8e-28 96.9 7.8 7.8e-28 96.9 5.4 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF3815) MFS_1 PF07690.11 EPS26401.1 - 3e-33 115.0 38.9 7.6e-28 97.2 19.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily AMP-binding PF00501.23 EPS26402.1 - 1.3e-68 231.3 0.0 1.8e-68 230.8 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPS26402.1 - 0.0054 17.6 0.0 0.013 16.4 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pectate_lyase_3 PF12708.2 EPS26403.1 - 2.4e-47 161.9 17.3 4e-35 121.9 4.5 3.1 3 1 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EPS26403.1 - 0.00026 20.3 7.7 0.0017 17.8 0.0 3.3 3 0 0 3 3 3 2 N terminal extension of bacteriophage endosialidase DUF3292 PF11696.3 EPS26406.1 - 8.9e-244 810.1 0.0 1e-243 809.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3292) PRT_C PF08372.5 EPS26406.1 - 0.026 14.0 0.1 0.047 13.1 0.1 1.3 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal MIP PF00230.15 EPS26407.1 - 9.8e-48 162.5 10.6 1.3e-47 162.2 7.4 1.1 1 0 0 1 1 1 1 Major intrinsic protein NAD_binding_1 PF00175.16 EPS26409.1 - 3.6e-14 53.2 0.0 7.3e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EPS26409.1 - 4.6e-09 36.3 0.0 8.1e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EPS26409.1 - 1.7e-06 27.9 0.0 1.4e-05 25.0 0.0 2.1 1 1 1 2 2 2 1 Ferric reductase NAD binding domain Globin PF00042.17 EPS26409.1 - 3.2e-06 27.4 0.0 1e-05 25.8 0.0 1.9 2 0 0 2 2 2 1 Globin Protoglobin PF11563.3 EPS26409.1 - 0.014 15.0 0.0 0.033 13.8 0.0 1.7 1 0 0 1 1 1 0 Protoglobin DUF3932 PF13068.1 EPS26411.1 - 0.098 12.7 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3932) HLH PF00010.21 EPS26412.1 - 2.4e-10 39.9 0.5 4.9e-10 38.9 0.3 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain AA_permease_2 PF13520.1 EPS26414.1 - 8.5e-53 179.4 53.9 1.1e-52 179.0 37.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPS26414.1 - 1.5e-24 86.2 42.7 1.9e-24 85.8 29.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4235 PF14019.1 EPS26414.1 - 0.036 13.8 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4235) DUF3493 PF11998.3 EPS26414.1 - 0.12 12.2 1.7 0.21 11.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3493) DUF1182 PF06681.8 EPS26414.1 - 1.9 7.6 11.0 0.1 11.8 3.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1182) Pro-kuma_activ PF09286.6 EPS26417.1 - 4e-37 127.4 0.6 1.2e-36 125.8 0.1 2.1 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EPS26417.1 - 2.4e-12 46.6 0.1 3.9e-12 45.8 0.1 1.3 1 0 0 1 1 1 1 Subtilase family CBM_20 PF00686.14 EPS26418.1 - 2.6e-36 123.0 0.2 2.6e-36 123.0 0.2 1.9 2 0 0 2 2 2 1 Starch binding domain Chitin_bind_3 PF03067.10 EPS26418.1 - 4.2e-09 36.9 1.2 2.7e-05 24.5 0.0 2.5 2 0 0 2 2 2 2 Chitin binding domain CBM_25 PF03423.8 EPS26418.1 - 0.017 15.1 0.0 0.047 13.7 0.0 1.8 1 1 0 1 1 1 0 Carbohydrate binding domain (family 25) CCER1 PF15482.1 EPS26419.1 - 0.07 12.7 0.1 0.076 12.6 0.0 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 Herpes_UL46 PF03387.9 EPS26420.1 - 0.062 11.5 0.0 0.067 11.3 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL46 protein DUF883 PF05957.8 EPS26421.1 - 0.032 14.6 13.8 7.3 7.0 0.0 5.4 2 1 4 6 6 6 0 Bacterial protein of unknown function (DUF883) Peptidase_C39_2 PF13529.1 EPS26421.1 - 0.041 14.2 0.2 0.83 10.0 0.0 2.8 3 1 0 3 3 3 0 Peptidase_C39 like family XH PF03469.9 EPS26421.1 - 0.071 12.7 0.1 0.071 12.7 0.1 4.4 1 1 1 4 4 4 0 XH domain PsbQ PF05757.6 EPS26421.1 - 0.35 10.2 4.1 4 6.7 0.0 3.3 3 1 1 4 4 4 0 Oxygen evolving enhancer protein 3 (PsbQ) UPF0449 PF15136.1 EPS26421.1 - 7.1 6.9 10.5 59 3.9 0.0 4.1 3 1 2 5 5 5 0 Uncharacterised protein family UPF0449 TraG-D_C PF12696.2 EPS26422.1 - 0.062 13.1 1.0 0.1 12.4 0.7 1.3 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG T4SS-DNA_transf PF02534.9 EPS26422.1 - 0.11 11.1 1.7 0.14 10.7 1.1 1.1 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Sporozoite_P67 PF05642.6 EPS26422.1 - 3.2 5.5 10.8 4.1 5.1 7.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Con-6 PF10346.4 EPS26424.1 - 3.1e-25 87.2 9.9 1.6e-15 56.2 0.8 2.2 2 0 0 2 2 2 2 Conidiation protein 6 Toxin_52 PF15605.1 EPS26424.1 - 0.017 15.0 0.5 0.24 11.3 0.0 2.1 2 0 0 2 2 2 0 Putative toxin 52 SpoIIIAH PF12685.2 EPS26424.1 - 0.022 14.2 0.3 4.9 6.5 0.0 2.1 1 1 0 2 2 2 0 SpoIIIAH-like protein Toxin_43 PF15604.1 EPS26424.1 - 0.098 12.7 4.1 0.13 12.3 2.8 1.2 1 0 0 1 1 1 0 Putative toxin 43 Pro_CA PF00484.14 EPS26424.1 - 0.17 11.9 2.0 0.18 11.7 1.4 1.1 1 0 0 1 1 1 0 Carbonic anhydrase LEA_3 PF03242.8 EPS26424.1 - 0.19 12.0 2.5 0.7 10.1 0.6 2.0 1 1 0 2 2 2 0 Late embryogenesis abundant protein DUF3533 PF12051.3 EPS26425.1 - 6e-130 433.4 15.5 6.9e-130 433.2 10.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) NPCC PF08058.6 EPS26425.1 - 0.39 10.5 5.6 0.17 11.7 0.5 2.7 3 0 0 3 3 3 0 Nuclear pore complex component PMG PF05287.7 EPS26426.1 - 0.1 12.3 0.3 0.12 12.1 0.2 1.1 1 0 0 1 1 1 0 PMG protein DnaJ PF00226.26 EPS26428.1 - 1.3e-17 63.2 0.3 1.3e-17 63.2 0.2 2.2 2 0 0 2 2 2 1 DnaJ domain DUF2803 PF10972.3 EPS26428.1 - 0.22 10.9 4.6 0.23 10.9 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2803) FUSC PF04632.7 EPS26428.1 - 2.1 6.6 4.6 3.1 6.1 3.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family V_ATPase_I PF01496.14 EPS26428.1 - 2.4 5.8 10.6 4 5.1 7.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family OmpH PF03938.9 EPS26428.1 - 3.4 7.5 36.9 0.021 14.7 15.7 2.6 2 2 0 2 2 2 0 Outer membrane protein (OmpH-like) Complex1_LYR PF05347.10 EPS26429.1 - 8.8e-05 22.2 3.2 0.00011 21.9 1.5 1.7 1 1 1 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EPS26429.1 - 0.00072 19.7 0.2 0.0012 18.9 0.1 1.4 1 0 0 1 1 1 1 Complex1_LYR-like RRM_5 PF13893.1 EPS26430.1 - 1.1e-08 34.8 0.0 2e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPS26430.1 - 1.7e-08 33.9 0.0 3.2e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS26430.1 - 5.6e-05 23.0 0.0 9.8e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPS26430.1 - 0.0023 17.6 0.0 0.0036 17.0 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Sterol_MT_C PF08498.5 EPS26431.1 - 2.4e-27 94.6 0.0 3.8e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EPS26431.1 - 1.9e-21 76.3 0.0 3.8e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPS26431.1 - 3.2e-16 59.2 0.0 4.5e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPS26431.1 - 2.1e-13 50.5 0.0 3.8e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPS26431.1 - 2.1e-13 50.2 0.0 3.6e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS26431.1 - 5.6e-10 39.8 0.0 1.2e-09 38.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPS26431.1 - 7.4e-10 38.3 0.0 2.5e-09 36.6 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EPS26431.1 - 9.5e-10 38.0 0.0 1.3e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 EPS26431.1 - 2.5e-09 37.4 0.0 5e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPS26431.1 - 4e-08 33.2 0.0 1.3e-07 31.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EPS26431.1 - 0.00019 20.9 0.0 0.0003 20.3 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.9 EPS26431.1 - 0.0012 18.2 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.15 EPS26431.1 - 0.0022 17.0 0.0 0.0037 16.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.14 EPS26431.1 - 0.0032 17.0 0.0 0.0055 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 EPS26431.1 - 0.0059 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PrmA PF06325.8 EPS26431.1 - 0.007 15.5 0.0 0.014 14.5 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_29 PF03141.11 EPS26431.1 - 0.0099 14.2 0.0 0.013 13.8 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_32 PF13679.1 EPS26431.1 - 0.067 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain UPF0020 PF01170.13 EPS26431.1 - 0.084 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 TehB PF03848.9 EPS26431.1 - 0.14 11.3 0.3 0.65 9.1 0.0 1.9 2 0 0 2 2 2 0 Tellurite resistance protein TehB PALP PF00291.20 EPS26433.1 - 6.4e-42 143.8 1.8 7.5e-42 143.6 1.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme MFS_1 PF07690.11 EPS26434.1 - 2.1e-41 141.7 20.4 2.1e-41 141.7 14.1 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS26434.1 - 5.3e-19 68.1 15.2 8.1e-19 67.5 10.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EPS26434.1 - 4.8e-05 21.7 1.1 9.1e-05 20.8 0.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 EPS26434.1 - 0.067 11.2 1.9 0.17 9.8 0.2 2.3 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Phosphoesterase PF04185.9 EPS26435.1 - 2.1e-31 109.5 3.0 6.7e-31 107.8 1.9 1.8 1 1 0 1 1 1 1 Phosphoesterase family Fungal_trans_2 PF11951.3 EPS26436.1 - 7.1e-43 146.6 0.3 1e-42 146.1 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS26436.1 - 2.2e-08 33.8 11.0 3.7e-08 33.1 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.17 EPS26437.1 - 3.4e-136 454.2 0.1 3.8e-136 454.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EPS26437.1 - 2.5e-06 26.4 0.0 8.6e-06 24.7 0.0 1.9 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 EPS26437.1 - 0.00045 19.5 0.1 0.0014 17.9 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) GATase PF00117.23 EPS26438.1 - 2.5e-15 56.4 0.0 3.3e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EPS26438.1 - 0.003 17.0 0.3 0.018 14.4 0.2 2.0 1 1 0 1 1 1 1 Peptidase C26 Isochorismatase PF00857.15 EPS26442.1 - 1.3e-20 74.0 0.0 2.3e-16 60.2 0.0 2.6 2 1 0 2 2 2 2 Isochorismatase family Acetyltransf_1 PF00583.19 EPS26443.1 - 4e-12 46.0 0.0 5.6e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EPS26443.1 - 1.3e-07 31.7 0.0 2.2e-07 31.0 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EPS26443.1 - 4.8e-06 26.6 0.1 1.1e-05 25.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPS26443.1 - 7e-05 22.6 0.0 0.0001 22.1 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPS26443.1 - 0.013 15.2 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein SnoaL_2 PF12680.2 EPS26444.1 - 0.0017 18.7 0.0 0.017 15.5 0.0 2.5 2 1 1 3 3 3 1 SnoaL-like domain SnoaL PF07366.7 EPS26444.1 - 0.022 14.3 0.0 0.13 11.8 0.0 2.2 2 0 0 2 2 2 0 SnoaL-like polyketide cyclase MFS_1 PF07690.11 EPS26446.1 - 1.9e-34 118.9 31.4 1.9e-34 118.9 21.8 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily GDC-P PF02347.11 EPS26447.1 - 1.1e-174 581.1 0.0 8.6e-162 538.6 0.0 2.7 3 0 0 3 3 3 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 EPS26447.1 - 8.3e-05 21.8 0.2 0.00016 20.8 0.1 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EPS26447.1 - 0.037 13.0 0.0 0.1 11.6 0.0 1.6 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family RhgB_N PF09284.5 EPS26448.1 - 1e-117 391.8 4.5 1.6e-117 391.2 3.1 1.3 1 0 0 1 1 1 1 Rhamnogalacturonase B, N-terminal CBM-like PF14683.1 EPS26448.1 - 6e-53 178.9 0.1 1.2e-51 174.6 0.0 2.6 3 0 0 3 3 3 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 EPS26448.1 - 1.8e-17 63.2 2.3 4.9e-17 61.8 1.6 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 EPS26448.1 - 8.9e-05 22.4 2.3 0.00046 20.1 0.3 3.0 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain DUF3823 PF12866.2 EPS26448.1 - 0.006 16.1 0.7 0.013 15.0 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3823) DUF2012 PF09430.5 EPS26448.1 - 0.16 11.8 0.0 0.32 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) Acylphosphatase PF00708.13 EPS26448.1 - 0.17 12.0 0.0 0.55 10.3 0.0 1.8 2 0 0 2 2 2 0 Acylphosphatase Peptidase_S28 PF05577.7 EPS26450.1 - 6.8e-56 189.6 1.8 3.6e-55 187.3 1.2 2.1 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Sugar_tr PF00083.19 EPS26451.1 - 4.5e-122 407.8 23.1 5.6e-122 407.5 16.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS26451.1 - 4.5e-22 78.2 28.3 4.5e-22 78.2 19.6 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF261 PF03196.8 EPS26451.1 - 1.8 8.5 5.2 0.21 11.5 0.5 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF261 Mannitol_dh_C PF08125.8 EPS26452.1 - 3.8e-78 262.0 0.0 5.3e-78 261.5 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 EPS26452.1 - 1.2e-44 151.9 0.0 1.9e-44 151.2 0.0 1.4 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain adh_short PF00106.20 EPS26453.1 - 2.1e-22 79.7 0.6 6.6e-22 78.2 0.4 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPS26453.1 - 1.4e-12 47.6 0.0 2e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPS26453.1 - 4e-08 32.9 0.0 5e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EPS26453.1 - 2.6e-07 30.6 0.0 3.6e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EPS26453.1 - 1.4e-05 25.1 0.0 2.4e-05 24.4 0.0 1.3 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EPS26453.1 - 0.00014 20.8 0.1 0.00025 20.0 0.0 1.4 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 EPS26453.1 - 0.00017 20.7 0.1 0.00024 20.1 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Med15_fungi PF05397.7 EPS26453.1 - 0.0031 17.4 0.1 0.006 16.5 0.1 1.4 1 0 0 1 1 1 1 Mediator complex subunit 15 DUF1776 PF08643.5 EPS26453.1 - 0.027 13.6 0.1 0.084 11.9 0.0 1.7 1 1 1 2 2 2 0 Fungal family of unknown function (DUF1776) NmrA PF05368.8 EPS26453.1 - 0.03 13.5 0.2 0.045 13.0 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family Eno-Rase_NADH_b PF12242.3 EPS26453.1 - 0.3 10.9 1.3 0.35 10.6 0.1 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 4HBT_3 PF13622.1 EPS26454.1 - 6.2e-38 130.9 4.0 7.2e-38 130.7 2.8 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EPS26454.1 - 3.9e-19 68.5 0.0 5.3e-14 51.9 0.0 3.0 2 1 0 2 2 2 2 Acyl-CoA thioesterase GST_N_3 PF13417.1 EPS26455.1 - 1.2e-09 38.2 0.0 2.5e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EPS26455.1 - 3.4e-08 33.3 0.0 8.6e-08 32.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EPS26455.1 - 0.00017 21.4 0.0 0.00034 20.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EPS26455.1 - 0.0042 17.5 0.0 0.0067 16.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1_2 PF13603.1 EPS26455.1 - 0.082 12.1 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 SLT PF01464.15 EPS26456.1 - 1.6e-12 46.9 0.7 3.9e-12 45.7 0.5 1.6 1 1 0 1 1 1 1 Transglycosylase SLT domain Lysozyme_like PF13702.1 EPS26456.1 - 0.0063 16.0 0.1 0.0093 15.4 0.1 1.3 1 0 0 1 1 1 1 Lysozyme-like Glucosaminidase PF01832.15 EPS26456.1 - 0.046 13.8 0.4 0.15 12.1 0.0 1.8 1 1 1 2 2 2 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase SLT_2 PF13406.1 EPS26456.1 - 0.047 12.5 0.0 0.08 11.8 0.0 1.3 1 0 0 1 1 1 0 Transglycosylase SLT domain F-box-like PF12937.2 EPS26457.1 - 0.05 13.3 0.2 0.16 11.7 0.1 1.9 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 EPS26457.1 - 0.17 11.6 0.6 3 7.5 0.1 2.6 2 0 0 2 2 2 0 F-box domain p450 PF00067.17 EPS26458.1 - 3.5e-74 250.0 0.0 4.5e-74 249.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Kin17_mid PF10357.4 EPS26459.1 - 1.4e-51 173.4 2.0 1.4e-51 173.4 1.4 2.1 2 1 1 3 3 3 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 EPS26459.1 - 4.2e-05 23.5 1.2 0.00011 22.2 0.8 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EPS26459.1 - 0.00031 20.8 1.5 0.00088 19.3 1.0 1.9 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EPS26459.1 - 0.031 14.3 0.9 0.031 14.3 0.6 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) MHCassoc_trimer PF08831.5 EPS26459.1 - 1.1 9.1 4.2 1.5 8.7 0.1 2.7 3 0 0 3 3 3 0 Class II MHC-associated invariant chain trimerisation domain AKAP95 PF04988.7 EPS26459.1 - 4.3 7.0 9.8 0.11 12.2 1.9 1.9 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) Actin PF00022.14 EPS26460.1 - 6.7e-21 74.1 0.0 6.1e-20 70.9 0.0 2.3 2 1 0 2 2 2 1 Actin CBFD_NFYB_HMF PF00808.18 EPS26461.1 - 3.5e-18 65.4 0.4 6e-18 64.6 0.3 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EPS26461.1 - 0.00014 21.9 0.0 0.00022 21.2 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 EPS26461.1 - 0.016 14.9 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated DUF3510 PF12022.3 EPS26461.1 - 0.11 12.5 1.1 0.27 11.3 0.6 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3510) SPOB_ab PF14682.1 EPS26461.1 - 0.14 11.9 0.3 0.18 11.5 0.2 1.2 1 0 0 1 1 1 0 Sporulation initiation phospho-transferase B, C-terminal Mrr_N PF14338.1 EPS26461.1 - 0.2 11.7 1.1 0.27 11.3 0.3 1.6 2 0 0 2 2 2 0 Mrr N-terminal domain adh_short PF00106.20 EPS26462.1 - 1.6e-33 116.0 1.0 3.5e-33 114.8 0.4 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EPS26462.1 - 3e-13 49.8 0.3 4.6e-13 49.2 0.2 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EPS26462.1 - 2.8e-12 46.9 0.0 3.7e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EPS26462.1 - 3.6e-07 30.3 0.3 5.9e-07 29.6 0.2 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPS26462.1 - 3.6e-05 23.3 0.0 0.00017 21.1 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EPS26462.1 - 0.00046 19.5 0.5 0.00081 18.7 0.4 1.4 1 0 0 1 1 1 1 NmrA-like family CoA_binding_2 PF13380.1 EPS26462.1 - 0.013 15.6 0.1 0.2 11.8 0.0 2.2 2 0 0 2 2 2 0 CoA binding domain Shikimate_DH PF01488.15 EPS26462.1 - 0.019 15.0 0.0 0.032 14.3 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EPS26462.1 - 0.021 15.2 0.0 0.16 12.3 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Rifin_STEVOR PF02009.11 EPS26462.1 - 0.029 14.0 0.0 0.039 13.5 0.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family 3Beta_HSD PF01073.14 EPS26462.1 - 0.064 11.9 0.1 0.1 11.2 0.0 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EPS26462.1 - 0.077 13.3 0.3 0.91 9.8 0.0 2.3 1 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 EPS26462.1 - 0.11 12.3 0.3 0.2 11.4 0.2 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 EPS26462.1 - 0.13 11.4 0.0 0.2 10.7 0.0 1.4 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) zf-CCCH PF00642.19 EPS26463.1 - 7.2e-09 35.1 17.3 2.8e-07 30.0 1.5 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 EPS26463.1 - 0.00013 21.7 0.0 0.00022 20.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPS26463.1 - 0.009 15.6 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SCRG1 PF15224.1 EPS26463.1 - 0.53 10.1 5.0 0.45 10.3 0.2 2.4 2 0 0 2 2 2 0 Scrapie-responsive protein 1 SMC_Nse1 PF07574.8 EPS26464.1 - 4.5e-36 124.3 0.0 6e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 EPS26464.1 - 3.4e-11 42.9 9.7 3.4e-11 42.9 6.7 1.7 2 0 0 2 2 2 1 RING-like domain C1_1 PF00130.17 EPS26464.1 - 0.022 14.4 3.5 0.022 14.4 2.4 2.2 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-Apc11 PF12861.2 EPS26464.1 - 0.023 14.5 2.8 0.042 13.6 2.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger F420_ligase PF01996.11 EPS26464.1 - 0.04 12.9 0.1 0.06 12.4 0.1 1.2 1 0 0 1 1 1 0 F420-0:Gamma-glutamyl ligase zf-RING_2 PF13639.1 EPS26464.1 - 0.053 13.3 7.4 0.095 12.5 5.1 1.4 1 0 0 1 1 1 0 Ring finger domain DUF1018 PF06252.7 EPS26464.1 - 0.085 13.3 0.1 0.92 10.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1018) Coronavirus_5 PF05528.6 EPS26464.1 - 0.089 12.6 3.7 4.2 7.2 0.1 2.9 2 1 1 3 3 3 0 Coronavirus gene 5 protein FANCL_C PF11793.3 EPS26464.1 - 0.63 10.0 5.7 2.5 8.1 3.9 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4 PF00097.20 EPS26464.1 - 0.93 9.2 5.8 2.1 8.0 4.0 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Glyco_hydro_65m PF03632.10 EPS26466.1 - 6.5e-89 298.1 3.5 3e-88 296.0 2.4 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 EPS26466.1 - 3e-48 164.3 0.6 6.1e-48 163.3 0.4 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.10 EPS26466.1 - 8.3e-09 35.3 0.1 1.6e-08 34.5 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, C-terminal domain Catalase PF00199.14 EPS26467.1 - 2.1e-161 536.9 0.1 2.7e-161 536.5 0.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EPS26467.1 - 2.9e-18 65.4 1.0 4.6e-17 61.6 0.1 2.4 2 0 0 2 2 2 1 Catalase-related immune-responsive Acetyltransf_1 PF00583.19 EPS26468.1 - 2.5e-11 43.4 0.0 3.4e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPS26468.1 - 2.8e-08 33.7 0.0 4.2e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPS26468.1 - 3.5e-08 33.5 0.4 5.3e-07 29.7 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPS26468.1 - 4.6e-05 23.2 0.5 0.0026 17.5 0.1 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPS26468.1 - 0.005 16.5 0.0 0.015 15.0 0.0 1.8 1 1 0 1 1 1 1 FR47-like protein MOZ_SAS PF01853.13 EPS26468.1 - 0.14 11.3 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family Epimerase PF01370.16 EPS26469.1 - 6.2e-17 61.8 0.1 3e-16 59.6 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPS26469.1 - 7.6e-17 60.9 0.0 1.3e-16 60.1 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EPS26469.1 - 8.5e-13 48.7 0.1 2.4e-12 47.2 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EPS26469.1 - 1.4e-09 37.2 0.0 0.0013 17.6 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.8 EPS26469.1 - 3.9e-07 29.5 0.0 1.5e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 EPS26469.1 - 3.6e-06 26.9 0.6 1e-05 25.5 0.4 1.7 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EPS26469.1 - 4.9e-06 25.6 0.1 7.1e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EPS26469.1 - 0.00039 20.1 0.4 0.0019 17.8 0.3 1.9 1 1 0 1 1 1 1 KR domain DapB_N PF01113.15 EPS26469.1 - 0.091 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF427 PF04248.7 EPS26470.1 - 1.1e-27 95.5 0.8 1.2e-27 95.4 0.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) S1-like PF14444.1 EPS26470.1 - 0.18 11.5 0.5 18 5.1 0.0 3.1 2 1 1 3 3 3 0 S1-like Metallothio_Euk PF12749.2 EPS26471.1 - 0.0055 16.7 1.9 0.0055 16.7 1.3 1.8 2 0 0 2 2 2 1 Eukaryotic metallothionein HrpA_pilin PF09589.5 EPS26471.1 - 0.79 10.1 6.2 18 5.8 4.3 2.1 1 1 0 1 1 1 0 HrpA pilus formation protein Cupin_2 PF07883.6 EPS26472.1 - 1.2e-09 37.5 0.0 2.7e-09 36.3 0.0 1.7 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.17 EPS26472.1 - 0.0083 15.5 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 EPS26472.1 - 0.15 11.4 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Esterase_phd PF10503.4 EPS26473.1 - 1.8e-10 40.4 4.2 3.9e-05 23.0 0.2 2.5 2 1 0 2 2 2 2 Esterase PHB depolymerase CBM_1 PF00734.13 EPS26473.1 - 2e-08 33.7 11.4 2e-08 33.7 7.9 3.5 3 0 0 3 3 3 1 Fungal cellulose binding domain Glyco_transf_20 PF00982.16 EPS26474.1 - 8.1e-146 486.2 0.0 9.1e-146 486.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 EPS26474.1 - 5e-08 32.5 0.0 1.1e-06 28.2 0.0 2.4 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EPS26474.1 - 0.00015 21.9 0.0 0.071 13.2 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 DUF1931 PF09123.6 EPS26474.1 - 0.037 13.9 0.1 0.061 13.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) GMC_oxred_N PF00732.14 EPS26476.1 - 2.3e-67 227.2 0.2 3.6e-67 226.5 0.0 1.4 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EPS26476.1 - 2.1e-35 122.1 0.0 3.5e-35 121.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EPS26476.1 - 9.1e-07 28.0 0.0 0.019 13.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EPS26476.1 - 1.6e-06 27.2 0.1 0.00081 18.3 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 EPS26476.1 - 2.4e-05 22.9 0.4 0.0017 16.9 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 EPS26476.1 - 4.9e-05 23.2 0.0 0.00013 21.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EPS26476.1 - 6.8e-05 22.8 1.0 0.021 14.6 0.3 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPS26476.1 - 0.00012 22.2 0.1 0.11 12.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EPS26476.1 - 0.00027 20.0 0.1 0.00042 19.3 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EPS26476.1 - 0.00035 19.7 0.1 0.00077 18.6 0.1 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 EPS26476.1 - 0.0026 17.5 0.1 0.017 14.8 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EPS26476.1 - 0.024 15.0 0.0 0.083 13.3 0.0 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EPS26476.1 - 0.048 12.5 0.0 4.1 6.2 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 EPS26476.1 - 0.079 11.5 0.2 0.13 10.8 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase DUF3431 PF11913.3 EPS26480.1 - 3.6e-59 199.9 0.0 4.4e-59 199.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) p450 PF00067.17 EPS26481.1 - 9.9e-55 185.8 0.0 1.2e-54 185.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 EPS26482.1 - 2e-05 23.6 0.1 3.5e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS26482.1 - 6e-05 22.8 9.3 0.00012 21.8 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CoA_trans PF01144.18 EPS26483.1 - 8.3e-99 329.1 1.1 2.1e-59 200.3 0.0 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 EPS26483.1 - 0.0031 17.2 0.1 0.0064 16.1 0.1 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain DALR_2 PF09190.6 EPS26484.1 - 0.042 14.1 0.1 1.2 9.3 0.1 2.4 2 0 0 2 2 2 0 DALR domain HEAT_2 PF13646.1 EPS26484.1 - 0.06 13.6 0.9 0.25 11.6 0.1 2.3 2 1 0 2 2 2 0 HEAT repeats MFS_1 PF07690.11 EPS26485.1 - 7e-36 123.6 23.8 7e-36 123.6 16.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EPS26485.1 - 9.6e-05 21.9 0.9 9.6e-05 21.9 0.6 2.2 3 1 0 3 3 3 1 Ion channel regulatory protein UNC-93 DUF2970 PF11174.3 EPS26485.1 - 0.042 13.4 4.3 0.6 9.7 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2970) DUF1281 PF06924.6 EPS26485.1 - 0.092 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) MFS_1 PF07690.11 EPS26488.1 - 2.2e-31 108.8 42.8 7.6e-23 80.7 15.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.17 EPS26489.1 - 3.8e-71 239.9 0.0 4.5e-71 239.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_1 PF00175.16 EPS26490.1 - 6.5e-33 113.5 0.0 1.7e-32 112.2 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EPS26490.1 - 5.5e-29 100.2 0.0 1.5e-28 98.8 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 EPS26490.1 - 1.1e-23 82.8 0.1 1.9e-23 82.0 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 EPS26490.1 - 8.7e-07 28.9 0.0 0.00012 21.9 0.0 2.5 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EPS26490.1 - 0.00014 21.7 0.0 0.0013 18.6 0.0 2.4 1 1 0 1 1 1 1 Siderophore-interacting FAD-binding domain Collar PF07484.7 EPS26490.1 - 0.11 12.2 0.1 5.5 6.8 0.0 2.6 2 0 0 2 2 2 0 Phage Tail Collar Domain DUF3990 PF13151.1 EPS26491.1 - 0.16 11.3 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3990) p450 PF00067.17 EPS26492.1 - 2.3e-36 125.3 0.0 3.4e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 TRI5 PF06330.6 EPS26493.1 - 3.6e-26 91.7 0.1 4.5e-26 91.3 0.1 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Methyltransf_25 PF13649.1 EPS26494.1 - 0.053 13.8 0.0 0.097 13.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain AMP-binding PF00501.23 EPS26495.1 - 1.4e-78 264.2 0.0 2e-78 263.6 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EPS26495.1 - 3e-30 105.1 0.0 2e-24 85.9 0.0 3.7 3 1 0 3 3 3 2 Condensation domain PP-binding PF00550.20 EPS26495.1 - 2.3e-06 27.7 0.0 6.3e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF2850 PF11012.3 EPS26495.1 - 0.25 11.5 0.5 0.59 10.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2850) p450 PF00067.17 EPS26496.1 - 4.7e-79 266.0 0.0 5.7e-79 265.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Snf7 PF03357.16 EPS26498.1 - 1.9e-06 27.3 2.2 2.4e-06 27.0 1.5 1.1 1 0 0 1 1 1 1 Snf7 DUF4157 PF13699.1 EPS26498.1 - 0.034 14.2 5.3 0.062 13.4 2.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4157) Remorin_C PF03763.8 EPS26498.1 - 1.7 8.2 14.4 2.9 7.4 10.0 1.4 1 1 0 1 1 1 0 Remorin, C-terminal region bZIP_2 PF07716.10 EPS26499.1 - 1.8e-11 43.6 17.0 1.8e-11 43.6 11.8 2.7 2 1 1 3 3 3 2 Basic region leucine zipper bZIP_1 PF00170.16 EPS26499.1 - 0.00036 20.4 18.3 0.00036 20.4 12.7 2.1 2 1 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.12 EPS26499.1 - 0.00059 20.0 14.9 0.0013 18.9 10.3 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor APG6 PF04111.7 EPS26499.1 - 1.9 7.4 10.4 3.1 6.7 7.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 HAUS-augmin3 PF14932.1 EPS26499.1 - 2.6 7.1 10.3 4.2 6.4 7.2 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DivIC PF04977.10 EPS26499.1 - 3.2 7.3 7.7 0.35 10.3 1.3 2.1 1 1 1 2 2 2 0 Septum formation initiator N_methyl_3 PF13633.1 EPS26500.1 - 0.15 11.9 1.1 0.26 11.2 0.8 1.4 1 0 0 1 1 1 0 Prokaryotic N-terminal methylation site N_methyl_2 PF13544.1 EPS26500.1 - 0.24 10.9 0.9 0.49 9.9 0.6 1.6 1 0 0 1 1 1 0 Type IV pilin N-term methylation site GFxxxE Asp-B-Hydro_N PF05279.6 EPS26502.1 - 0.11 12.3 6.6 0.14 11.9 4.5 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Kdo PF06293.9 EPS26503.1 - 0.0001 21.4 0.3 0.00021 20.4 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPS26503.1 - 0.0045 16.7 1.0 0.0045 16.7 0.7 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPS26503.1 - 0.011 15.2 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase PF00069.20 EPS26503.1 - 0.022 13.9 0.0 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain RIO1 PF01163.17 EPS26503.1 - 0.17 11.1 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Bystin PF05291.6 EPS26504.1 - 4.7e-127 423.0 0.0 7.1e-127 422.4 0.0 1.2 1 0 0 1 1 1 1 Bystin Endonuc-BsobI PF09194.5 EPS26504.1 - 0.073 11.9 0.0 0.15 10.9 0.0 1.5 1 0 0 1 1 1 0 Restriction endonuclease BsobI Amidase PF01425.16 EPS26506.1 - 1.4e-114 383.4 0.7 1.7e-114 383.1 0.5 1.0 1 0 0 1 1 1 1 Amidase ADH_zinc_N PF00107.21 EPS26507.1 - 1.5e-13 50.4 0.0 3.2e-13 49.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.20 EPS26507.1 - 0.0057 16.5 0.2 0.01 15.7 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPS26507.1 - 0.019 14.5 0.3 0.032 13.8 0.2 1.3 1 0 0 1 1 1 0 KR domain ADH_N PF08240.7 EPS26507.1 - 0.087 12.5 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Ribosomal_L12 PF00542.14 EPS26507.1 - 0.1 12.6 0.6 0.22 11.5 0.4 1.5 1 0 0 1 1 1 0 Ribosomal protein L7/L12 C-terminal domain Metallophos PF00149.23 EPS26508.1 - 1.8e-10 40.5 2.3 3.1e-10 39.7 1.6 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Transket_pyr PF02779.19 EPS26509.1 - 2e-44 151.1 0.0 3.3e-44 150.5 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EPS26509.1 - 3.1e-35 120.8 0.1 1.1e-34 118.9 0.0 2.0 3 0 0 3 3 3 1 Transketolase, C-terminal domain GntR PF00392.16 EPS26509.1 - 0.16 11.4 0.4 3.9 6.9 0.1 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family zf-C2H2 PF00096.21 EPS26510.1 - 0.0052 17.0 1.2 0.013 15.8 0.8 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-met PF12874.2 EPS26510.1 - 0.0063 16.6 0.3 0.013 15.6 0.2 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EPS26510.1 - 0.012 15.9 0.4 0.029 14.6 0.2 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EPS26510.1 - 0.073 13.2 1.9 0.12 12.5 1.3 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EPS26510.1 - 0.073 13.1 0.1 0.12 12.5 0.1 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 EPS26510.1 - 0.083 12.8 0.5 0.15 12.0 0.3 1.4 1 0 0 1 1 1 0 C2H2-type zinc finger Peptidase_M48 PF01435.13 EPS26510.1 - 0.1 12.1 0.2 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 Peptidase family M48 DUF1691 PF07950.6 EPS26511.1 - 1.8e-49 166.2 8.0 2.2e-34 117.7 1.7 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) VirB8 PF04335.8 EPS26511.1 - 0.029 13.9 0.1 0.05 13.1 0.1 1.3 1 0 0 1 1 1 0 VirB8 protein TRM PF02005.11 EPS26512.1 - 4.5e-115 384.5 0.0 2.6e-98 329.3 0.0 2.1 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 EPS26512.1 - 7.4e-07 28.9 0.0 1.2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.1 EPS26512.1 - 2.9e-06 26.9 0.0 6.6e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPS26512.1 - 0.00013 21.9 0.0 0.00039 20.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS26512.1 - 0.0012 19.4 0.0 0.0028 18.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 EPS26512.1 - 0.0013 17.8 0.0 0.0021 17.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase PrmA PF06325.8 EPS26512.1 - 0.011 14.8 0.5 0.022 13.8 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) DUF2067 PF09840.4 EPS26512.1 - 0.02 14.3 0.0 0.046 13.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2067) ketoacyl-synt PF00109.21 EPS26514.1 - 2e-20 73.3 0.0 4.8e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.15 EPS26514.1 - 4.2e-18 65.2 0.1 9.6e-18 64.0 0.0 1.6 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 EPS26514.1 - 6.6e-11 42.0 0.0 1.6e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EPS26514.1 - 9.7e-06 25.6 0.0 2.2e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPS26514.1 - 0.0019 17.9 0.0 0.0049 16.5 0.0 1.7 1 0 0 1 1 1 1 KR domain ACTH_domain PF00976.13 EPS26515.1 - 0.027 14.3 0.2 0.053 13.3 0.2 1.5 1 0 0 1 1 1 0 Corticotropin ACTH domain Acyl_transf_1 PF00698.16 EPS26516.1 - 4.4e-83 279.2 0.0 1.1e-80 271.3 0.0 3.1 3 0 0 3 3 3 2 Acyl transferase domain MaoC_dehydratas PF01575.14 EPS26516.1 - 3.9e-39 132.8 0.0 1.1e-38 131.3 0.0 1.8 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 EPS26516.1 - 2.4e-31 107.2 0.2 7.2e-31 105.7 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 EPS26516.1 - 2.9e-20 72.4 0.1 1.2e-19 70.3 0.0 2.2 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase NMO PF03060.10 EPS26516.1 - 0.0023 17.1 0.1 0.02 14.0 0.1 2.2 2 0 0 2 2 2 1 Nitronate monooxygenase TFIIF_alpha PF05793.7 EPS26517.1 - 2.9e-10 39.1 57.6 1.1e-09 37.2 36.7 2.8 2 1 0 2 2 2 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Daxx PF03344.10 EPS26517.1 - 0.11 10.9 31.9 0.0026 16.3 16.9 1.8 2 0 0 2 2 2 0 Daxx Family MIP-T3 PF10243.4 EPS26517.1 - 0.15 10.4 44.7 0.28 9.5 23.8 2.2 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Curto_V2 PF07325.6 EPS26517.1 - 2 8.0 9.6 0.032 13.8 0.8 2.1 2 0 0 2 2 2 0 Curtovirus V2 protein OPT PF03169.10 EPS26518.1 - 4.4e-204 679.4 33.5 5e-204 679.2 23.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF383 PF04063.9 EPS26519.1 - 9.6e-72 240.5 1.5 1.6e-71 239.8 0.0 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF383) DUF384 PF04064.8 EPS26519.1 - 1.4e-21 75.7 3.4 3.7e-21 74.4 0.9 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF384) Inositol_P PF00459.20 EPS26520.1 - 9.9e-66 221.8 0.0 1.1e-65 221.6 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DUF676 PF05057.9 EPS26521.1 - 6.7e-41 139.9 0.0 4.1e-26 91.6 0.0 3.2 3 0 0 3 3 3 3 Putative serine esterase (DUF676) PGAP1 PF07819.8 EPS26521.1 - 0.077 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein DAGK_cat PF00781.19 EPS26522.1 - 1.1e-13 50.7 0.0 1.9e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain His_Phos_2 PF00328.17 EPS26523.1 - 1.4e-119 399.4 0.2 1.8e-119 399.1 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 EPS26523.1 - 1.1e-06 28.3 0.0 2.3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Utp21 PF04192.7 EPS26524.1 - 1.4e-79 266.5 0.0 2.2e-79 265.9 0.0 1.3 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 EPS26524.1 - 7e-19 66.9 17.6 0.0003 20.5 0.2 9.0 9 0 0 9 9 9 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EPS26524.1 - 0.0086 14.4 0.4 0.04 12.1 0.1 2.3 2 0 0 2 2 2 1 Cytochrome D1 heme domain Nup160 PF11715.3 EPS26524.1 - 0.069 11.2 0.2 2.3 6.2 0.1 2.7 3 0 0 3 3 3 0 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EPS26524.1 - 0.14 11.9 0.0 0.59 9.9 0.0 2.1 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, middle region XPG_I_2 PF12813.2 EPS26525.1 - 1.5e-68 230.9 0.0 2e-68 230.5 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.13 EPS26525.1 - 0.0057 16.6 0.0 0.014 15.4 0.0 1.6 1 0 0 1 1 1 1 XPG I-region Fcf1 PF04900.7 EPS26526.1 - 1.4e-39 134.2 0.3 1.4e-39 134.2 0.2 1.7 2 0 0 2 2 2 1 Fcf1 CDH PF02611.10 EPS26528.1 - 1.9e-06 27.2 0.0 3e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 CDP-diacylglycerol pyrophosphatase Pec_lyase_C PF00544.14 EPS26530.1 - 4.7e-21 75.1 4.0 8.4e-21 74.3 2.8 1.4 1 0 0 1 1 1 1 Pectate lyase Glyco_hydro_43 PF04616.9 EPS26531.1 - 1.7e-12 47.0 3.1 2.9e-12 46.2 2.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 HTH_Tnp_Tc5 PF03221.11 EPS26538.1 - 0.00072 19.3 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.14 EPS26538.1 - 0.004 16.3 0.0 0.006 15.7 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3806 PF12713.2 EPS26538.1 - 0.1 12.0 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3806) Strep_67kDa_ant PF06100.6 EPS26543.1 - 2.6e-112 375.7 0.0 3e-112 375.5 0.0 1.0 1 0 0 1 1 1 1 Streptococcal 67 kDa myosin-cross-reactive antigen like family NAD_binding_8 PF13450.1 EPS26543.1 - 2.9e-06 27.2 0.0 6.4e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EPS26543.1 - 0.0053 16.5 0.0 0.0098 15.6 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EPS26543.1 - 0.083 11.7 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain PPDK_N PF01326.14 EPS26544.1 - 1.2e-95 320.2 0.0 2.3e-95 319.4 0.0 1.3 1 0 0 1 1 1 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers_C PF02896.13 EPS26544.1 - 1.8e-60 204.3 0.0 2.9e-60 203.6 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PEP-utilizers PF00391.18 EPS26544.1 - 2.7e-24 84.5 0.8 7.2e-24 83.1 0.5 1.8 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain Ldh_1_N PF00056.18 EPS26545.1 - 5.7e-30 103.9 0.0 9.3e-30 103.3 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EPS26545.1 - 6.3e-27 94.4 0.0 9.6e-27 93.8 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain UDPG_MGDP_dh_N PF03721.9 EPS26545.1 - 0.03 13.7 0.4 0.091 12.1 0.3 1.8 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.16 EPS26545.1 - 0.031 14.1 0.7 0.1 12.4 0.3 1.9 2 0 0 2 2 2 0 ThiF family F420_oxidored PF03807.12 EPS26545.1 - 0.053 13.9 2.1 1.1 9.7 1.2 3.0 3 1 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 EPS26545.1 - 0.08 12.9 0.7 0.3 11.1 0.2 2.1 2 0 0 2 2 2 0 TrkA-N domain EcKinase PF02958.15 EPS26546.1 - 2.5e-14 53.0 0.0 1.6e-13 50.4 0.0 2.0 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.18 EPS26546.1 - 1.5e-09 37.9 0.0 1.5e-09 37.9 0.0 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPS26546.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1679 PF07914.6 EPS26546.1 - 0.17 10.4 0.0 0.34 9.5 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1679) YccV-like PF08755.6 EPS26547.1 - 4.5e-26 90.6 0.0 8.6e-26 89.7 0.0 1.5 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.1 EPS26547.1 - 7.4e-14 51.4 0.0 3.5e-13 49.3 0.0 2.1 2 0 0 2 2 2 1 Transglutaminase-like superfamily F-box-like PF12937.2 EPS26547.1 - 3.6e-11 42.6 0.8 7.9e-11 41.5 0.6 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EPS26547.1 - 3.1e-09 36.2 1.1 4.2e-09 35.8 0.0 1.8 2 0 0 2 2 2 1 F-box domain DnaJ PF00226.26 EPS26548.1 - 1e-26 92.4 0.3 1e-26 92.4 0.2 2.5 3 0 0 3 3 2 1 DnaJ domain zf-C2H2_jaz PF12171.3 EPS26548.1 - 8e-10 38.5 4.2 8e-10 38.5 2.9 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EPS26548.1 - 1.7e-08 34.3 3.1 1.7e-08 34.3 2.1 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EPS26548.1 - 1.5e-06 28.2 6.0 0.00016 21.6 1.0 2.5 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 EPS26548.1 - 0.00013 21.7 8.2 0.098 12.6 0.3 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EPS26548.1 - 0.00023 21.3 11.1 0.061 13.6 1.8 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPS26548.1 - 0.0041 17.3 9.4 0.47 10.8 0.7 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger Transcrip_act PF04949.8 EPS26548.1 - 0.013 15.1 3.5 0.015 14.9 0.0 2.5 2 0 0 2 2 2 0 Transcriptional activator zf-FCS PF06467.9 EPS26548.1 - 0.052 13.1 2.4 1.1 9.0 0.1 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif C1_4 PF07975.7 EPS26548.1 - 0.085 12.8 1.7 2.7 8.0 0.1 2.5 2 0 0 2 2 2 0 TFIIH C1-like domain CpXC PF14353.1 EPS26548.1 - 0.15 12.0 2.5 3.8 7.4 0.0 3.0 3 0 0 3 3 3 0 CpXC protein LIM PF00412.17 EPS26548.1 - 0.24 11.5 2.9 3.5 7.7 0.3 2.4 2 0 0 2 2 2 0 LIM domain Cytochrome_C554 PF13435.1 EPS26548.1 - 0.7 9.9 9.5 0.27 11.2 0.6 2.9 2 1 0 2 2 2 0 Cytochrome c554 and c-prime zf-LYAR PF08790.6 EPS26548.1 - 0.74 9.5 5.1 3.9 7.2 0.4 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-H2C2_2 PF13465.1 EPS26548.1 - 2.4 8.6 4.4 3.3 8.1 0.1 2.8 3 0 0 3 3 3 0 Zinc-finger double domain R3H PF01424.17 EPS26549.1 - 1.6e-12 46.8 0.0 4.9e-12 45.3 0.0 1.9 1 0 0 1 1 1 1 R3H domain G-patch PF01585.18 EPS26549.1 - 3.6e-10 39.4 0.2 8.7e-10 38.2 0.1 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EPS26549.1 - 0.00012 21.8 0.3 0.00012 21.8 0.2 3.5 4 0 0 4 4 4 1 DExH-box splicing factor binding site SAM_2 PF07647.12 EPS26549.1 - 0.08 12.7 0.3 0.4 10.5 0.0 2.3 3 0 0 3 3 3 0 SAM domain (Sterile alpha motif) Peptidase_C54 PF03416.14 EPS26551.1 - 1.3e-95 319.6 0.0 1.7e-95 319.3 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Histone PF00125.19 EPS26552.1 - 2.9e-22 78.5 0.3 4.2e-22 78.0 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EPS26552.1 - 0.00022 21.2 0.9 0.0004 20.3 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EPS26552.1 - 0.00041 20.5 0.0 0.00069 19.8 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.8 EPS26552.1 - 0.031 13.7 0.0 0.044 13.2 0.0 1.2 1 0 0 1 1 1 0 Replication protein C N-terminal domain Histone PF00125.19 EPS26553.1 - 8.7e-26 89.8 0.0 1.1e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EPS26553.1 - 1.3e-05 25.1 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Complex1_LYR PF05347.10 EPS26554.1 - 1.7e-09 37.3 0.4 2.4e-09 36.8 0.3 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EPS26554.1 - 2.7e-07 30.7 0.2 3.6e-07 30.2 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EPS26554.1 - 0.082 13.3 0.1 0.13 12.8 0.1 1.3 1 0 0 1 1 1 0 Complex1_LYR-like 2-oxoacid_dh PF00198.18 EPS26555.1 - 1.1e-79 266.9 0.1 1.7e-79 266.3 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EPS26555.1 - 1.4e-19 69.5 2.2 2.8e-19 68.5 1.5 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD PF00529.15 EPS26555.1 - 0.0017 17.7 0.6 0.0035 16.6 0.4 1.6 1 1 0 1 1 1 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 EPS26555.1 - 0.014 15.0 0.6 0.44 10.2 0.1 2.4 1 1 1 2 2 2 0 Biotin-lipoyl like RnfC_N PF13375.1 EPS26555.1 - 0.02 14.5 0.6 0.29 10.8 0.0 2.8 1 1 2 3 3 3 0 RnfC Barrel sandwich hybrid domain HlyD_3 PF13437.1 EPS26555.1 - 0.039 14.2 0.3 1.1 9.6 0.1 2.3 1 1 1 2 2 2 0 HlyD family secretion protein Tape_meas_lam_C PF09718.5 EPS26555.1 - 0.11 12.4 0.0 6.6 6.7 0.0 2.5 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) GAGA_bind PF06217.7 EPS26555.1 - 0.15 12.0 5.5 0.21 11.4 3.8 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family Neisseria_TspB PF05616.8 EPS26555.1 - 0.54 8.5 7.8 0.74 8.1 5.4 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein MIP-T3 PF10243.4 EPS26555.1 - 0.59 8.5 23.1 0.84 8.0 16.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CMV_1a PF12467.3 EPS26555.1 - 4.6 7.5 11.1 14 5.9 6.7 2.3 2 0 0 2 2 2 0 Cucumber mosaic virus 1a protein family Hid1 PF12722.2 EPS26555.1 - 7.3 4.1 8.1 9.3 3.7 5.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SRP-alpha_N PF04086.8 EPS26555.1 - 8.1 5.7 18.7 13 5.0 12.0 1.8 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal MADF_DNA_bdg PF10545.4 EPS26556.1 - 0.057 13.5 0.1 0.49 10.6 0.0 2.3 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like PCMT PF01135.14 EPS26557.1 - 1.5e-61 207.6 0.0 2.3e-60 203.7 0.0 2.0 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EPS26557.1 - 1.8e-12 47.8 0.0 3e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPS26557.1 - 8.1e-10 38.4 0.0 1.3e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EPS26557.1 - 4.8e-06 26.3 0.0 7.7e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPS26557.1 - 1.1e-05 25.3 0.0 1.8e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPS26557.1 - 1.2e-05 25.0 0.0 1.8e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPS26557.1 - 1.4e-05 25.3 0.0 2.7e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPS26557.1 - 0.00023 21.5 0.0 0.0004 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EPS26557.1 - 0.00026 21.0 0.0 0.00036 20.5 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_11 PF08241.7 EPS26557.1 - 0.0041 17.5 0.0 0.01 16.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EPS26557.1 - 0.0082 15.5 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.9 EPS26557.1 - 0.026 13.9 0.0 0.056 12.8 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain RrnaAD PF00398.15 EPS26557.1 - 0.068 12.1 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DnaJ PF00226.26 EPS26558.1 - 3.3e-24 84.3 3.9 3.7e-24 84.2 0.8 2.6 2 0 0 2 2 2 1 DnaJ domain TPR_11 PF13414.1 EPS26558.1 - 3e-21 74.8 6.5 7.7e-09 35.0 0.0 6.4 4 2 3 7 7 7 6 TPR repeat TPR_2 PF07719.12 EPS26558.1 - 6e-17 60.1 9.7 0.0043 16.8 0.0 9.5 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_1 PF00515.23 EPS26558.1 - 1.5e-16 59.1 0.8 1.4e-05 24.4 0.0 8.1 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.1 EPS26558.1 - 9.3e-13 47.5 13.7 0.087 13.5 0.1 8.2 3 3 5 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.1 EPS26558.1 - 2.1e-10 40.9 18.4 7.2e-05 23.3 0.5 6.2 3 1 5 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 EPS26558.1 - 5.4e-10 39.4 7.6 0.0027 17.9 0.0 5.4 3 3 2 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.1 EPS26558.1 - 2e-09 37.1 7.0 0.011 15.5 0.0 5.1 2 1 4 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 EPS26558.1 - 5.1e-09 35.2 0.0 0.021 14.5 0.0 6.6 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 EPS26558.1 - 4.6e-05 23.2 1.7 0.15 12.3 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 EPS26558.1 - 7.7e-05 22.8 14.8 1 9.9 0.0 7.6 8 1 0 8 8 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 EPS26558.1 - 0.00041 20.2 12.2 0.45 10.4 0.1 6.6 4 3 3 7 7 7 3 Tetratricopeptide repeat Apc3 PF12895.2 EPS26558.1 - 0.002 18.2 6.7 1.1 9.3 0.1 4.3 2 2 3 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 RF-1 PF00472.15 EPS26559.1 - 4e-34 116.8 1.4 8.5e-34 115.7 1.0 1.5 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 EPS26559.1 - 1.1e-27 96.0 0.0 5.1e-27 93.8 0.0 2.1 2 0 0 2 2 2 1 PCRF domain Mito_carr PF00153.22 EPS26560.1 - 6.7e-57 189.1 5.4 1.6e-23 82.1 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein DEAD PF00270.24 EPS26561.1 - 3.1e-41 140.6 0.0 4.4e-41 140.1 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPS26561.1 - 8.9e-24 83.1 0.1 1.6e-23 82.3 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SMC_N PF02463.14 EPS26562.1 - 9.3e-21 74.0 18.2 1.3e-19 70.3 12.7 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EPS26562.1 - 1e-11 45.5 25.6 1e-11 45.5 17.7 4.7 3 2 0 3 3 3 1 AAA domain AAA_21 PF13304.1 EPS26562.1 - 6.8e-10 39.3 1.1 1.2e-05 25.4 0.1 2.5 2 0 0 2 2 2 2 AAA domain SMC_hinge PF06470.8 EPS26562.1 - 1.8e-07 31.1 0.0 1.1e-06 28.5 0.0 2.5 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.1 EPS26562.1 - 5.1e-05 22.4 0.3 5.1e-05 22.4 0.2 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EPS26562.1 - 0.00013 21.3 0.0 0.00029 20.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 EPS26562.1 - 0.0016 18.3 0.0 0.0046 16.8 0.0 1.8 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.22 EPS26562.1 - 0.052 13.8 0.2 0.052 13.8 0.1 5.3 3 2 0 3 3 3 0 ABC transporter Peptidase_M20 PF01546.23 EPS26563.1 - 3.4e-31 108.2 0.0 5e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EPS26563.1 - 7.9e-12 44.9 0.0 1.5e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain MRP-L20 PF12824.2 EPS26564.1 - 3.4e-64 215.7 5.6 4e-64 215.5 3.9 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.6 EPS26564.1 - 0.028 14.2 0.2 0.051 13.3 0.1 1.5 1 0 0 1 1 1 0 Neugrin Hyccin PF09790.4 EPS26564.1 - 0.031 13.1 0.2 0.056 12.3 0.1 1.5 1 0 0 1 1 1 0 Hyccin Cys_Met_Meta_PP PF01053.15 EPS26566.1 - 3.5e-37 127.5 0.0 4.9e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EPS26566.1 - 0.0016 17.4 0.0 0.0029 16.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II BSD PF03909.12 EPS26566.1 - 0.12 12.1 0.0 1.8 8.3 0.0 2.6 2 0 0 2 2 2 0 BSD domain Nrap PF03813.9 EPS26567.1 - 0 1166.1 0.0 0 1165.9 0.0 1.0 1 0 0 1 1 1 1 Nrap protein HWE_HK PF07536.9 EPS26567.1 - 0.0061 16.9 0.2 0.043 14.2 0.0 2.6 3 0 0 3 3 3 1 HWE histidine kinase I-set PF07679.11 EPS26568.1 - 0.0025 17.6 0.2 0.38 10.6 0.0 4.2 4 0 0 4 4 4 1 Immunoglobulin I-set domain Peptidase_C12 PF01088.16 EPS26569.1 - 6.6e-64 215.0 0.0 1.1e-63 214.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Oxysterol_BP PF01237.13 EPS26570.1 - 1.2e-56 191.7 0.0 3.5e-56 190.2 0.0 1.7 1 1 0 1 1 1 1 Oxysterol-binding protein U1snRNP70_N PF12220.3 EPS26570.1 - 2.2 8.6 6.8 25 5.2 0.1 2.8 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Cnd1_N PF12922.2 EPS26572.1 - 1.3e-58 197.3 0.2 1.3e-58 197.3 0.1 2.0 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term Cnd1 PF12717.2 EPS26572.1 - 1.2e-56 191.3 1.8 3.4e-51 173.6 0.3 3.0 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EPS26572.1 - 1.7e-13 50.6 7.1 1.8e-06 28.1 0.0 5.1 3 2 1 4 4 4 2 HEAT repeats HEAT PF02985.17 EPS26572.1 - 4.2e-09 35.7 12.1 0.22 11.6 0.0 7.4 8 0 0 8 8 8 3 HEAT repeat Adaptin_N PF01602.15 EPS26572.1 - 6.2e-07 28.1 8.4 0.0029 15.9 0.5 4.8 4 1 0 4 4 4 2 Adaptin N terminal region HEAT_EZ PF13513.1 EPS26572.1 - 9.1e-06 26.0 10.6 0.31 11.5 0.0 6.1 6 0 0 6 6 6 2 HEAT-like repeat DUF2435 PF10363.4 EPS26572.1 - 0.00075 19.3 0.1 1.5 8.7 0.0 4.0 2 1 1 3 3 3 1 Protein of unknown function (DUF2435) Cnd3 PF12719.2 EPS26572.1 - 0.072 12.0 11.1 0.41 9.5 3.3 4.0 2 2 1 3 3 3 0 Nuclear condensing complex subunits, C-term domain Cohesin_HEAT PF12765.2 EPS26572.1 - 0.13 12.2 8.6 7.7 6.5 0.1 5.4 6 0 0 6 6 6 0 HEAT repeat associated with sister chromatid cohesion FlbD PF06289.6 EPS26572.1 - 0.14 11.5 0.1 0.33 10.3 0.0 1.6 1 0 0 1 1 1 0 Flagellar protein (FlbD) Pkinase PF00069.20 EPS26573.1 - 1.7e-42 145.4 0.0 3.9e-19 68.8 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EPS26573.1 - 1.3e-09 37.4 0.0 5e-05 22.5 0.0 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 EPS26573.1 - 0.0019 17.9 0.1 0.21 11.2 0.1 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EPS26573.1 - 0.0055 15.7 0.0 1.2 8.0 0.0 2.3 2 0 0 2 2 2 2 Kinase-like CENP-B_dimeris PF09026.5 EPS26573.1 - 0.61 10.3 11.4 18 5.6 0.0 3.4 3 0 0 3 3 3 0 Centromere protein B dimerisation domain OTU PF02338.14 EPS26574.1 - 1.8e-12 47.9 0.0 3e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EPS26574.1 - 0.0026 17.1 0.0 0.01 15.1 0.0 1.8 1 1 1 2 2 2 1 Peptidase C65 Otubain Bromodomain PF00439.20 EPS26575.1 - 4.6e-40 135.4 4.4 1.3e-19 69.8 0.2 2.7 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 EPS26575.1 - 4.9e-16 58.5 1.3 9.6e-16 57.6 0.9 1.5 1 0 0 1 1 1 1 BAH domain DUF1353 PF07087.6 EPS26575.1 - 0.013 14.9 0.0 0.062 12.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1353) Nucleoplasmin PF03066.10 EPS26575.1 - 5.2 6.5 13.8 0.094 12.2 4.6 1.7 2 0 0 2 2 2 0 Nucleoplasmin PAT1 PF09770.4 EPS26575.1 - 9.4 4.3 24.1 18 3.4 16.7 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-CCCH PF00642.19 EPS26576.1 - 1.9e-10 40.1 10.9 8.4e-06 25.3 1.6 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EPS26576.1 - 0.82 9.7 16.0 2.4 8.2 2.7 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type TBPIP PF07106.8 EPS26577.1 - 1.2e-31 109.5 0.5 1.4e-31 109.3 0.3 1.0 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Macoilin PF09726.4 EPS26577.1 - 0.00028 19.3 2.6 0.00032 19.1 1.8 1.1 1 0 0 1 1 1 1 Transmembrane protein Penicillinase_R PF03965.11 EPS26577.1 - 0.001 19.1 0.3 0.002 18.1 0.2 1.6 1 1 0 1 1 1 1 Penicillinase repressor Mnd1 PF03962.10 EPS26577.1 - 0.0045 16.6 2.1 0.0096 15.5 1.4 1.6 1 1 0 1 1 1 1 Mnd1 family EzrA PF06160.7 EPS26577.1 - 0.021 13.0 2.2 0.027 12.6 1.5 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA CCDC92 PF14916.1 EPS26577.1 - 0.032 13.8 0.9 24 4.5 0.0 3.3 3 0 0 3 3 3 0 Coiled-coil domain of unknown function DMPK_coil PF08826.5 EPS26577.1 - 0.047 13.5 5.9 0.11 12.3 4.1 1.7 1 0 0 1 1 1 0 DMPK coiled coil domain like IncA PF04156.9 EPS26577.1 - 0.063 12.8 8.1 0.088 12.3 5.6 1.3 1 1 0 1 1 1 0 IncA protein TrmB PF01978.14 EPS26577.1 - 0.087 12.5 0.1 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF4414 PF14377.1 EPS26577.1 - 0.16 11.9 7.3 3.6 7.5 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4414) DUF4140 PF13600.1 EPS26577.1 - 0.21 12.0 9.0 0.18 12.2 1.0 2.7 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4349 PF14257.1 EPS26577.1 - 0.42 9.8 10.3 1.4 8.0 7.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) TMF_TATA_bd PF12325.3 EPS26577.1 - 0.77 9.5 7.1 4.7 6.9 0.6 2.7 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding DivIC PF04977.10 EPS26577.1 - 0.88 9.0 9.7 0.31 10.5 0.7 2.7 2 1 1 3 3 3 0 Septum formation initiator Prefoldin PF02996.12 EPS26577.1 - 1.3 8.6 4.6 2 8.1 1.2 2.4 2 1 1 3 3 3 0 Prefoldin subunit TPR_MLP1_2 PF07926.7 EPS26577.1 - 1.6 8.4 9.4 4.5 7.0 0.4 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 EPS26577.1 - 2 8.2 7.1 1.5 8.6 3.8 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1192 PF06698.6 EPS26577.1 - 9.7 6.0 10.7 4.6 7.1 1.7 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) Sel1 PF08238.7 EPS26578.1 - 4.3e-19 68.5 21.4 2.3e-07 31.1 0.0 7.0 7 0 0 7 7 7 5 Sel1 repeat TPR_1 PF00515.23 EPS26578.1 - 0.00076 18.9 0.1 0.0052 16.3 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EPS26578.1 - 0.0016 18.0 0.2 0.0016 18.0 0.1 2.8 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 EPS26578.1 - 0.14 12.1 0.0 0.14 12.1 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EPS26578.1 - 0.41 11.4 0.0 0.41 11.4 0.0 4.0 4 1 1 5 5 5 0 Tetratricopeptide repeat Helicase_C_2 PF13307.1 EPS26579.1 - 2e-57 193.7 0.1 8.1e-57 191.8 0.0 2.1 3 0 0 3 3 3 1 Helicase C-terminal domain DEAD_2 PF06733.10 EPS26579.1 - 1.3e-45 154.9 0.0 2.8e-45 153.8 0.0 1.6 1 0 0 1 1 1 1 DEAD_2 Ribosomal_L18e PF00828.14 EPS26580.1 - 1.7e-34 118.9 0.0 2.3e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Abhydrolase_6 PF12697.2 EPS26581.1 - 1.2e-07 31.8 0.1 1.6e-07 31.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPS26581.1 - 1.3e-06 28.2 0.0 2.1e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EPS26581.1 - 0.051 12.7 0.0 0.34 10.0 0.0 2.0 1 1 1 2 2 2 0 Prolyl oligopeptidase family PLDc PF00614.17 EPS26582.1 - 1.3e-13 50.2 0.3 2.7e-06 26.9 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EPS26582.1 - 6.1e-12 45.3 0.0 3.3e-07 30.1 0.0 2.6 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 EPS26582.1 - 1.3e-07 31.4 0.0 9e-07 28.6 0.0 2.5 2 1 0 2 2 2 1 PX domain PAP_assoc PF03828.14 EPS26583.1 - 0.00036 20.4 0.0 0.004 17.0 0.0 2.4 1 1 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EPS26583.1 - 0.012 15.8 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyltransferase domain Glyco_transf_20 PF00982.16 EPS26584.1 - 2.8e-147 491.0 0.0 6.5e-147 489.8 0.0 1.5 2 0 0 2 2 2 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EPS26584.1 - 1.4e-90 302.3 0.0 2.2e-90 301.7 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase MFS_1 PF07690.11 EPS26585.1 - 1.8e-18 66.4 54.4 4.8e-18 64.9 34.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PP28 PF10252.4 EPS26586.1 - 6e-32 109.5 12.6 6e-32 109.5 8.8 2.8 3 0 0 3 3 3 2 Casein kinase substrate phosphoprotein PP28 DUF2570 PF10828.3 EPS26586.1 - 0.98 9.0 7.1 1 8.9 0.6 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2570) CENP-B_dimeris PF09026.5 EPS26586.1 - 2 8.7 9.4 1.5 9.1 2.7 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain UNC-50 PF05216.8 EPS26587.1 - 2.8e-87 291.7 6.7 3.6e-87 291.4 4.6 1.1 1 0 0 1 1 1 1 UNC-50 family YobH PF13996.1 EPS26587.1 - 0.044 13.7 0.9 0.1 12.5 0.6 1.6 1 0 0 1 1 1 0 YobH-like protein DUF3278 PF11683.3 EPS26587.1 - 2.4 8.1 10.2 0.1 12.5 0.8 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3278) Sec7 PF01369.15 EPS26588.1 - 8.1e-41 139.7 0.0 1.7e-40 138.7 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EPS26588.1 - 1.4e-19 70.3 0.2 7.8e-19 67.9 0.0 2.3 3 0 0 3 3 3 1 Pleckstrin homology domain Tektin PF03148.9 EPS26588.1 - 0.011 14.3 0.1 0.018 13.5 0.1 1.2 1 0 0 1 1 1 0 Tektin family Flavodoxin_1 PF00258.20 EPS26588.1 - 0.021 14.8 0.0 0.05 13.5 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin DUF4618 PF15397.1 EPS26588.1 - 0.18 11.0 0.1 0.31 10.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) SR-25 PF10500.4 EPS26589.1 - 0.0049 16.3 37.2 0.0064 15.9 25.8 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein eIF3_subunit PF08597.5 EPS26589.1 - 0.021 14.3 26.7 0.029 13.9 18.5 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit GAGA_bind PF06217.7 EPS26589.1 - 0.032 14.2 23.0 0.031 14.2 15.9 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family SpoIIP PF07454.6 EPS26589.1 - 0.043 12.9 12.5 0.047 12.8 8.7 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) YL1 PF05764.8 EPS26589.1 - 0.055 13.0 34.1 0.062 12.8 23.6 1.0 1 0 0 1 1 1 0 YL1 nuclear protein DUF1168 PF06658.7 EPS26589.1 - 0.064 12.7 34.9 0.082 12.4 24.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) PcfK PF14058.1 EPS26589.1 - 0.067 13.3 27.7 0.083 13.0 19.2 1.1 1 0 0 1 1 1 0 PcfK-like protein DUF3807 PF12720.2 EPS26589.1 - 0.072 13.2 19.4 0.081 13.0 13.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Pox_Ag35 PF03286.9 EPS26589.1 - 0.092 12.2 24.3 0.11 12.0 16.8 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NPR3 PF03666.8 EPS26589.1 - 0.11 10.9 19.1 0.11 10.9 13.2 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SprA-related PF12118.3 EPS26589.1 - 0.15 11.3 16.5 0.16 11.2 11.5 1.0 1 0 0 1 1 1 0 SprA-related family Tim54 PF11711.3 EPS26589.1 - 0.15 10.5 13.5 0.15 10.5 9.3 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Cas_Csy4 PF09618.5 EPS26589.1 - 0.16 11.7 11.5 0.18 11.5 8.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) NARP1 PF12569.3 EPS26589.1 - 0.17 10.5 27.7 0.18 10.4 19.2 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Vfa1 PF08432.5 EPS26589.1 - 0.2 11.6 30.9 0.22 11.5 21.4 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Bud13 PF09736.4 EPS26589.1 - 0.23 11.7 22.4 0.26 11.5 15.5 1.1 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DUF2956 PF11169.3 EPS26589.1 - 0.26 11.2 30.9 0.33 10.9 21.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) MIP-T3 PF10243.4 EPS26589.1 - 0.28 9.6 32.4 0.28 9.5 22.5 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 AIF_C PF14721.1 EPS26589.1 - 0.29 11.3 10.0 0.32 11.2 6.9 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term YqfQ PF14181.1 EPS26589.1 - 0.31 11.0 23.1 0.35 10.8 16.0 1.2 1 0 0 1 1 1 0 YqfQ-like protein DUF4355 PF14265.1 EPS26589.1 - 0.32 10.9 32.7 0.4 10.6 22.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) DUF2413 PF10310.4 EPS26589.1 - 0.33 9.7 21.3 0.36 9.6 14.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) FLO_LFY PF01698.11 EPS26589.1 - 0.39 9.5 16.3 0.45 9.3 11.3 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein LicD PF04991.8 EPS26589.1 - 0.41 10.7 17.0 0.46 10.5 11.8 1.1 1 0 0 1 1 1 0 LicD family TraV PF09676.5 EPS26589.1 - 0.51 11.0 9.1 0.71 10.5 6.3 1.3 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) Hid1 PF12722.2 EPS26589.1 - 0.52 7.9 12.4 0.55 7.8 8.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Dala_Dala_lig_N PF01820.16 EPS26589.1 - 0.64 10.3 7.5 0.76 10.0 5.2 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase N-terminus BSMAP PF12280.3 EPS26589.1 - 0.73 9.6 11.0 0.83 9.5 7.6 1.1 1 0 0 1 1 1 0 Brain specific membrane anchored protein AAA_11 PF13086.1 EPS26589.1 - 0.75 9.3 15.1 0.77 9.2 10.5 1.1 1 0 0 1 1 1 0 AAA domain DUF1764 PF08576.5 EPS26589.1 - 0.78 10.5 25.2 1 10.1 17.5 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Paramyxo_ncap PF00973.14 EPS26589.1 - 0.78 8.3 11.8 0.8 8.3 8.2 1.0 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DUF2828 PF11443.3 EPS26589.1 - 0.79 7.8 15.4 0.79 7.8 10.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Ycf1 PF05758.7 EPS26589.1 - 0.81 7.3 17.8 0.9 7.1 12.3 1.0 1 0 0 1 1 1 0 Ycf1 RR_TM4-6 PF06459.7 EPS26589.1 - 0.84 9.4 19.9 0.91 9.3 13.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM176 PF14851.1 EPS26589.1 - 0.88 9.2 9.1 1.2 8.8 6.3 1.3 1 0 0 1 1 1 0 FAM176 family LIM_bind PF01803.11 EPS26589.1 - 0.9 8.5 12.9 1 8.4 8.9 1.1 1 0 0 1 1 1 0 LIM-domain binding protein TAF1D PF15333.1 EPS26589.1 - 0.96 9.1 29.1 1.3 8.7 20.2 1.3 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D DUF2201_N PF13203.1 EPS26589.1 - 0.98 8.5 10.6 1 8.4 7.4 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain DDHD PF02862.12 EPS26589.1 - 1 9.0 14.7 1.2 8.8 10.2 1.1 1 0 0 1 1 1 0 DDHD domain DUF1800 PF08811.6 EPS26589.1 - 1.1 8.1 7.7 1.1 8.1 5.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) U79_P34 PF03064.11 EPS26589.1 - 1.1 8.6 20.8 1.2 8.6 14.4 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 FAM60A PF15396.1 EPS26589.1 - 1.2 8.8 23.2 1.4 8.6 16.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A RNA_pol_Rpb1_5 PF04998.12 EPS26589.1 - 1.3 8.2 12.7 1.3 8.1 8.8 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Rot1 PF10681.4 EPS26589.1 - 1.3 8.2 9.8 1.7 7.9 6.8 1.3 1 0 0 1 1 1 0 Chaperone for protein-folding within the ER, fungal EIIBC-GUT_N PF03612.9 EPS26589.1 - 1.4 8.5 11.4 1.5 8.3 7.9 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DDE_Tnp_1_4 PF13701.1 EPS26589.1 - 1.5 6.9 9.6 1.5 6.9 6.6 1.0 1 0 0 1 1 1 0 Transposase DDE domain group 1 SET PF00856.23 EPS26589.1 - 1.5 9.1 6.0 1.4 9.1 4.2 1.1 1 0 0 1 1 1 0 SET domain DUF3464 PF11947.3 EPS26589.1 - 1.5 8.2 21.9 1.9 7.9 15.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) GCD14 PF08704.5 EPS26589.1 - 1.7 8.1 9.6 1.7 8.1 6.7 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Hom_end_hint PF05203.11 EPS26589.1 - 1.7 8.2 11.5 1.8 8.2 8.0 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint DUF3513 PF12026.3 EPS26589.1 - 1.9 7.9 19.5 2.1 7.8 13.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) Kei1 PF08552.6 EPS26589.1 - 1.9 8.0 5.5 2 8.0 3.8 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 SpoVR PF04293.8 EPS26589.1 - 2 6.6 13.5 2.3 6.5 9.4 1.0 1 0 0 1 1 1 0 SpoVR like protein DUF2561 PF10812.3 EPS26589.1 - 2.1 7.8 3.9 2.5 7.6 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Rpn3_C PF08375.6 EPS26589.1 - 2.2 8.7 18.2 3.2e+02 1.7 12.6 2.1 1 1 0 1 1 1 0 Proteasome regulatory subunit C-terminal JAB PF01398.16 EPS26589.1 - 3 7.6 6.2 5.7 6.7 4.3 1.5 1 1 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease SelP_N PF04592.9 EPS26589.1 - 3 7.1 14.4 3.2 7.0 10.0 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region DDE_Tnp_1 PF01609.16 EPS26589.1 - 3.3 7.2 17.7 3.8 7.0 12.3 1.1 1 0 0 1 1 1 0 Transposase DDE domain DUF3408 PF11888.3 EPS26589.1 - 3.3 7.6 15.7 4.1 7.3 10.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) DDRGK PF09756.4 EPS26589.1 - 3.3 7.0 30.0 3.8 6.8 20.8 1.1 1 0 0 1 1 1 0 DDRGK domain Band_3_cyto PF07565.8 EPS26589.1 - 3.4 7.1 11.8 3.4 7.0 8.2 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF913 PF06025.7 EPS26589.1 - 3.4 6.3 7.0 3.4 6.3 4.8 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RNA_pol_3_Rpc31 PF11705.3 EPS26589.1 - 3.4 7.5 17.3 4 7.3 12.0 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Neur_chan_memb PF02932.11 EPS26589.1 - 3.4 7.4 11.8 3.7 7.3 8.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Folate_carrier PF01770.13 EPS26589.1 - 3.5 6.0 14.3 4.1 5.8 9.9 1.0 1 0 0 1 1 1 0 Reduced folate carrier CDC45 PF02724.9 EPS26589.1 - 4.3 5.2 15.0 4.5 5.1 10.4 1.0 1 0 0 1 1 1 0 CDC45-like protein Pex24p PF06398.6 EPS26589.1 - 4.4 5.9 10.1 4.4 6.0 7.0 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Serinc PF03348.10 EPS26589.1 - 5.1 5.7 10.6 5.5 5.5 7.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4337 PF14235.1 EPS26589.1 - 5.1 6.9 17.4 5.6 6.7 12.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF3987 PF13148.1 EPS26589.1 - 5.3 5.4 18.7 5.6 5.4 13.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Gti1_Pac2 PF09729.4 EPS26589.1 - 5.4 6.8 17.0 6.7 6.5 11.8 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Sre PF03125.13 EPS26589.1 - 5.4 5.8 11.1 6.1 5.6 7.7 1.0 1 0 0 1 1 1 0 C. elegans Sre G protein-coupled chemoreceptor DUF4175 PF13779.1 EPS26589.1 - 5.5 4.5 13.5 5.6 4.5 9.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Tfb4 PF03850.9 EPS26589.1 - 5.9 6.0 7.4 6.3 5.9 5.1 1.1 1 0 0 1 1 1 0 Transcription factor Tfb4 Atrophin-1 PF03154.10 EPS26589.1 - 6.3 4.8 12.2 6.5 4.7 8.5 1.0 1 0 0 1 1 1 0 Atrophin-1 family DUF2422 PF10337.4 EPS26589.1 - 6.5 5.4 7.4 7 5.3 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) DUF853 PF05872.7 EPS26589.1 - 6.6 4.9 8.1 6.7 4.9 5.6 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF694 PF05107.7 EPS26589.1 - 6.7 5.8 19.6 8.5 5.5 13.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF694) RP-C_C PF11800.3 EPS26589.1 - 7.5 6.2 11.2 8.3 6.0 7.8 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region RNA_pol_Rpb1_2 PF00623.15 EPS26589.1 - 7.6 6.4 9.6 8.5 6.3 6.7 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 2 Tubulin_2 PF13809.1 EPS26589.1 - 7.7 5.3 9.0 8.3 5.2 6.3 1.0 1 0 0 1 1 1 0 Tubulin like Presenilin PF01080.12 EPS26589.1 - 7.9 5.1 7.1 8.4 5.0 4.9 1.0 1 0 0 1 1 1 0 Presenilin AAA_23 PF13476.1 EPS26589.1 - 9 6.5 22.6 11 6.3 15.6 1.1 1 0 0 1 1 1 0 AAA domain RNA_pol_Rpc4 PF05132.9 EPS26589.1 - 9.4 6.2 19.5 12 5.8 13.5 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Zip PF02535.17 EPS26589.1 - 9.7 5.0 9.5 11 4.9 6.6 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Microtub_assoc PF07989.6 EPS26590.1 - 1.6e-24 85.5 10.8 1.6e-24 85.5 7.5 8.5 9 1 0 9 9 9 1 Microtubule associated Mto2_bdg PF12808.2 EPS26590.1 - 6.2e-20 71.0 26.9 2.4e-17 62.7 12.0 13.2 12 4 1 13 13 13 2 Micro-tubular organiser Mto1 C-term Mto2-binding region Reo_sigmaC PF04582.7 EPS26590.1 - 5.8e-06 25.7 3.8 5.8e-06 25.7 2.6 5.5 4 1 1 5 5 5 5 Reovirus sigma C capsid protein QRPTase_C PF01729.14 EPS26591.1 - 1e-47 161.7 0.2 3.6e-47 160.0 0.2 1.7 1 1 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 EPS26591.1 - 9.4e-23 79.8 0.0 2.9e-22 78.2 0.0 1.9 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Ribul_P_3_epim PF00834.14 EPS26591.1 - 0.038 13.1 0.0 0.18 10.8 0.0 1.9 1 1 1 2 2 2 0 Ribulose-phosphate 3 epimerase family Pectinesterase PF01095.14 EPS26592.1 - 7.8e-48 162.5 8.7 1e-47 162.2 6.0 1.1 1 0 0 1 1 1 1 Pectinesterase LETM1 PF07766.8 EPS26593.1 - 3.3e-06 26.3 0.1 0.0014 17.7 0.1 2.4 2 0 0 2 2 2 2 LETM1-like protein PAS_9 PF13426.1 EPS26594.1 - 1.4e-31 108.9 0.0 3.1e-18 66.0 0.0 3.5 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.6 EPS26594.1 - 7.1e-19 67.7 0.0 1.4e-11 44.3 0.0 4.0 3 1 0 3 3 3 3 PAS fold GATA PF00320.22 EPS26594.1 - 1.5e-13 49.8 7.1 3.1e-13 48.8 5.0 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.19 EPS26594.1 - 1.5e-13 50.5 0.0 0.001 18.8 0.0 3.5 3 0 0 3 3 3 3 PAS fold PAS_4 PF08448.5 EPS26594.1 - 1.1e-08 35.0 0.0 0.058 13.4 0.0 3.9 4 0 0 4 4 4 3 PAS fold PAS_11 PF14598.1 EPS26594.1 - 2.9e-07 30.4 0.0 0.036 14.0 0.0 2.9 2 0 0 2 2 2 2 PAS domain PAS_8 PF13188.1 EPS26594.1 - 0.00012 21.7 0.0 0.049 13.5 0.0 2.9 2 0 0 2 2 2 1 PAS domain VirE PF05272.6 EPS26594.1 - 0.18 11.2 0.0 0.37 10.2 0.0 1.4 1 0 0 1 1 1 0 Virulence-associated protein E Ras PF00071.17 EPS26595.1 - 2.7e-09 36.6 0.0 4e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Ras family FmdE PF02663.9 EPS26595.1 - 0.1 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Zn_clus PF00172.13 EPS26599.1 - 8.6e-09 35.1 13.2 1.4e-08 34.5 9.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldose_epim PF01263.15 EPS26602.1 - 1.2e-62 211.6 0.0 1.4e-62 211.5 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase ZZ PF00569.12 EPS26604.1 - 3.9e-21 74.3 58.8 7.7e-09 34.9 3.2 4.4 4 0 0 4 4 4 4 Zinc finger, ZZ type Btz PF09405.5 EPS26605.1 - 6.4e-34 116.8 5.0 6.4e-34 116.8 3.5 2.2 2 0 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding RRM_6 PF14259.1 EPS26606.1 - 3.5e-23 81.3 0.0 1.6e-12 47.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPS26606.1 - 2.7e-22 78.1 0.5 3.7e-13 48.8 0.0 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS26606.1 - 5.9e-09 35.6 0.3 0.00012 21.7 0.1 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Apc1 PF12859.2 EPS26606.1 - 0.09 13.0 1.8 0.34 11.1 0.1 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 1 Nup35_RRM_2 PF14605.1 EPS26606.1 - 0.15 11.8 0.0 2.9 7.7 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RNase_H2_suC PF08615.6 EPS26606.1 - 0.23 11.2 3.7 0.94 9.3 0.9 2.2 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) TLP-20 PF06088.6 EPS26606.1 - 3.4 7.2 10.8 0.72 9.5 3.2 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Pex14_N PF04695.8 EPS26606.1 - 4.7 7.2 10.8 5.7 6.9 0.4 3.1 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NOA36 PF06524.7 EPS26606.1 - 5.8 6.0 12.7 0.11 11.6 3.8 1.7 2 0 0 2 2 2 0 NOA36 protein Ino80_Iec3 PF14612.1 EPS26607.1 - 5.1e-78 262.3 4.0 7.3e-78 261.8 2.8 1.2 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling Sec34 PF04136.10 EPS26607.1 - 0.0015 18.2 1.5 0.0025 17.5 1.0 1.3 1 0 0 1 1 1 1 Sec34-like family ECR1_N PF14382.1 EPS26608.1 - 5e-11 41.7 0.1 1.1e-10 40.6 0.1 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 EPS26608.1 - 0.00066 19.5 0.1 0.012 15.5 0.1 2.5 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 UPF0227 PF05728.7 EPS26608.1 - 0.099 12.3 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) IFRD PF05004.8 EPS26609.1 - 6.5e-32 110.8 2.0 9.1e-32 110.3 1.4 1.2 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) Cnd3 PF12719.2 EPS26609.1 - 0.013 14.4 0.2 0.032 13.2 0.0 1.7 1 1 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain Ribophorin_II PF05817.9 EPS26609.1 - 0.061 11.5 1.0 0.081 11.1 0.7 1.1 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II HEAT PF02985.17 EPS26609.1 - 0.079 13.0 0.3 4 7.7 0.0 3.5 3 0 0 3 3 3 0 HEAT repeat Corona_nucleoca PF00937.13 EPS26609.1 - 0.36 9.7 8.5 0.62 8.9 5.9 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Sigma70_ner PF04546.8 EPS26609.1 - 0.6 9.6 10.7 0.27 10.8 1.5 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region Oxysterol_BP PF01237.13 EPS26610.1 - 2.6e-115 384.7 0.0 9.2e-115 382.8 0.0 1.8 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 EPS26610.1 - 3.7e-38 129.4 0.4 1.1e-37 127.9 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 EPS26610.1 - 2.1e-06 27.8 0.1 4.2e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EPS26610.1 - 0.00014 22.0 0.6 0.0012 19.0 0.4 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 EPS26610.1 - 0.051 13.4 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 PH domain EMP24_GP25L PF01105.19 EPS26610.1 - 0.17 11.6 0.0 0.41 10.3 0.0 1.6 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD SH2_2 PF14633.1 EPS26611.1 - 5.6e-84 280.6 0.0 1.4e-83 279.3 0.0 1.7 1 0 0 1 1 1 1 SH2 domain DLD PF14878.1 EPS26611.1 - 7e-38 129.2 4.1 7e-38 129.2 2.8 3.0 3 0 0 3 3 3 1 Death-like domain of SPT6 HHH_7 PF14635.1 EPS26611.1 - 6.9e-32 109.6 0.0 1.5e-31 108.5 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 EPS26611.1 - 1.4e-23 83.1 0.0 4.2e-23 81.5 0.0 1.9 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.1 EPS26611.1 - 8e-19 67.8 4.7 8e-19 67.8 3.3 2.9 2 1 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.1 EPS26611.1 - 3.3e-18 65.6 20.7 3.3e-18 65.6 14.3 5.6 6 0 0 6 6 6 1 Acidic N-terminal SPT6 SH2 PF00017.19 EPS26611.1 - 6.2e-05 22.7 0.0 0.00015 21.5 0.0 1.7 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.2 EPS26611.1 - 0.069 13.1 0.0 0.25 11.2 0.0 2.1 1 0 0 1 1 1 0 Helix-hairpin-helix motif B12-binding PF02310.14 EPS26611.1 - 0.072 12.9 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 B12 binding domain Pkinase PF00069.20 EPS26612.1 - 1e-59 201.8 0.0 1.3e-59 201.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS26612.1 - 1.8e-35 122.3 0.0 2.4e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPS26612.1 - 0.00016 20.7 0.0 0.00028 19.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EPS26612.1 - 0.075 11.8 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 HUN PF08729.5 EPS26614.1 - 5.5e-15 54.9 0.1 1.3e-14 53.7 0.1 1.6 1 0 0 1 1 1 1 HPC2 and ubinuclein domain DUF4544 PF15077.1 EPS26614.1 - 0.39 10.1 5.7 0.92 8.9 4.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4544) RPAP1_C PF08620.5 EPS26615.1 - 1e-28 98.9 0.0 1.8e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 EPS26615.1 - 2.4e-16 59.0 7.8 3.6e-16 58.4 4.8 1.7 2 0 0 2 2 2 1 RPAP1-like, N-terminal Apc1 PF12859.2 EPS26616.1 - 1.5e-29 102.3 0.1 4.7e-29 100.6 0.1 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 EPS26616.1 - 1.6e-06 28.0 9.7 9.1e-05 22.4 0.1 4.4 4 0 0 4 4 4 2 Proteasome/cyclosome repeat Lyase_aromatic PF00221.14 EPS26618.1 - 1.3e-161 538.3 8.1 1.6e-161 537.9 5.6 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase eIF2A PF08662.6 EPS26619.1 - 1.1e-84 283.0 0.0 4.8e-84 280.9 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EPS26619.1 - 0.00013 21.7 0.4 0.3 11.0 0.1 4.7 5 0 0 5 5 5 1 WD domain, G-beta repeat CDV3 PF15359.1 EPS26619.1 - 0.012 15.7 1.6 0.012 15.7 1.1 4.3 2 1 2 4 4 4 0 Carnitine deficiency-associated protein 3 Acetyltransf_13 PF13880.1 EPS26623.1 - 5.1e-30 103.0 0.0 1.3e-29 101.7 0.0 1.7 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 EPS26623.1 - 2e-16 59.2 0.2 3.5e-16 58.4 0.1 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO EMG1 PF03587.9 EPS26624.1 - 2.7e-78 261.9 0.0 3.2e-78 261.6 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Glyoxalase_2 PF12681.2 EPS26626.1 - 6.1e-08 33.2 0.0 1.2e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Glyoxalase-like domain Rick_17kDa_Anti PF05433.10 EPS26626.1 - 0.026 14.2 4.7 0.083 12.5 3.3 1.9 1 0 0 1 1 1 0 Glycine zipper 2TM domain Glyoxalase PF00903.20 EPS26626.1 - 0.027 14.4 2.3 0.083 12.8 0.0 2.7 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Fimbrial_PilY2 PF14481.1 EPS26626.1 - 0.052 12.9 0.0 0.14 11.5 0.0 1.7 1 0 0 1 1 1 0 Type 4 fimbrial biogenesis protein PilY2 Glyco_hydro_3 PF00933.16 EPS26627.1 - 7.5e-92 307.4 0.0 1.1e-91 307.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EPS26627.1 - 2.9e-54 184.0 0.1 2.6e-53 180.8 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EPS26627.1 - 2.7e-17 62.4 0.0 5.1e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF953 PF06110.6 EPS26628.1 - 2.6e-13 49.4 0.0 2.7e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.1 EPS26628.1 - 0.018 14.5 0.1 0.029 13.9 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin GMC_oxred_C PF05199.8 EPS26629.1 - 2.5e-33 115.3 0.1 4.1e-33 114.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EPS26629.1 - 3.7e-29 101.8 0.0 2e-25 89.5 0.0 2.6 2 1 0 2 2 2 2 GMC oxidoreductase NAD_binding_8 PF13450.1 EPS26629.1 - 0.0041 17.1 0.0 0.012 15.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EPS26629.1 - 0.018 13.8 0.1 0.031 13.1 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 EPS26629.1 - 0.023 14.5 0.0 0.082 12.7 0.0 1.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EPS26629.1 - 0.03 13.2 0.0 0.23 10.3 0.0 2.2 3 0 0 3 3 3 0 FAD dependent oxidoreductase ApbA PF02558.11 EPS26629.1 - 0.087 12.2 0.1 0.18 11.2 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UQ_con PF00179.21 EPS26630.1 - 5.5e-52 174.9 0.0 6.2e-52 174.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EPS26630.1 - 7.6e-05 22.4 0.0 9e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EPS26630.1 - 0.0026 17.6 0.0 0.0028 17.5 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EPS26630.1 - 0.02 14.5 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 UEV domain Acyl-CoA_dh_N PF02771.11 EPS26631.1 - 3.4e-26 92.0 0.1 7.8e-26 90.8 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 EPS26631.1 - 4.4e-25 88.5 0.6 8.1e-25 87.6 0.4 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EPS26631.1 - 6.2e-17 60.8 0.0 1.4e-16 59.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EPS26631.1 - 1.2e-08 35.2 0.8 1.2e-08 35.2 0.5 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Zn_clus PF00172.13 EPS26632.1 - 4.8e-09 35.9 8.3 1e-08 34.8 5.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EPS26632.1 - 0.00011 21.1 2.0 0.00034 19.5 1.4 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain TF_Zn_Ribbon PF08271.7 EPS26632.1 - 1.8 7.9 5.5 3.8 6.8 3.8 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding XPG_N PF00752.12 EPS26633.1 - 3.5e-32 110.6 0.3 2.6e-31 107.8 0.0 2.2 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I PF00867.13 EPS26633.1 - 9.3e-31 105.7 0.6 2e-30 104.6 0.0 1.9 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.15 EPS26633.1 - 1.4e-05 25.2 0.3 9.4e-05 22.5 0.0 2.4 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Linker_histone PF00538.14 EPS26634.1 - 7.2e-25 86.8 0.8 7.2e-25 86.8 0.6 1.8 2 0 0 2 2 2 1 linker histone H1 and H5 family DUF650 PF04894.7 EPS26634.1 - 0.064 12.7 1.0 0.084 12.3 0.4 1.4 1 1 0 1 1 1 0 Archaeal protein of unknown function (DUF650) Menin PF05053.8 EPS26634.1 - 4.7 5.2 13.8 5.4 5.0 9.5 1.2 1 0 0 1 1 1 0 Menin Glyco_hydro_18 PF00704.23 EPS26635.1 - 2.5e-76 257.3 2.0 3e-76 257.1 1.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.8 EPS26635.1 - 0.023 13.8 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 PIP5K PF01504.13 EPS26636.1 - 3.6e-86 288.3 0.1 5.2e-86 287.8 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Glyco_hydro_71 PF03659.9 EPS26636.1 - 0.02 13.3 0.2 0.037 12.5 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 71 ATP-sulfurylase PF01747.12 EPS26638.1 - 2.6e-87 291.6 0.0 3.5e-87 291.2 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 EPS26638.1 - 1.7e-60 203.2 0.0 2.7e-60 202.5 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 EPS26638.1 - 1.3e-49 167.6 0.0 2.3e-49 166.8 0.0 1.4 1 0 0 1 1 1 1 PUA-like domain AAA_33 PF13671.1 EPS26638.1 - 0.002 17.9 0.0 0.0048 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain CPT PF07931.7 EPS26638.1 - 0.018 14.6 0.1 0.14 11.7 0.1 2.1 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein KTI12 PF08433.5 EPS26638.1 - 0.096 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 hEGF PF12661.2 EPS26639.1 - 0.067 13.2 1.8 0.15 12.2 1.3 1.6 1 0 0 1 1 1 0 Human growth factor-like EGF DUF997 PF06196.7 EPS26639.1 - 0.12 11.9 0.7 0.21 11.1 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF997) CDK5_activator PF03261.10 EPS26639.1 - 0.17 11.2 4.0 0.42 9.8 2.8 1.6 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein EGF_2 PF07974.8 EPS26639.1 - 9.2 6.5 13.8 16 5.7 9.6 1.4 1 0 0 1 1 1 0 EGF-like domain NADH5_C PF06455.6 EPS26640.1 - 0.15 11.4 1.9 0.21 10.9 1.3 1.3 1 1 0 1 1 1 0 NADH dehydrogenase subunit 5 C-terminus SET PF00856.23 EPS26643.1 - 7e-17 62.1 1.0 7e-17 62.1 0.7 4.0 3 2 0 3 3 3 1 SET domain zf-DHHC PF01529.15 EPS26644.1 - 6.6e-35 120.0 7.8 1.2e-34 119.2 5.0 1.8 1 1 0 1 1 1 1 DHHC palmitoyltransferase PMT PF02366.13 EPS26646.1 - 1.6e-78 263.4 17.8 3.2e-78 262.4 12.3 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EPS26646.1 - 2.5e-53 180.4 0.0 4.8e-53 179.5 0.0 1.5 1 0 0 1 1 1 1 MIR domain DUF4231 PF14015.1 EPS26646.1 - 4.1 7.4 7.9 0.46 10.4 1.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) PRP21_like_P PF12230.3 EPS26647.1 - 4e-59 199.9 13.7 1.3e-58 198.2 9.5 1.7 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 EPS26647.1 - 3.1e-37 125.9 1.2 1e-19 69.8 0.0 2.3 2 0 0 2 2 2 2 Surp module DUF1517 PF07466.6 EPS26647.1 - 0.035 13.0 0.7 0.058 12.3 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Sas10_Utp3 PF04000.10 EPS26648.1 - 2.2e-16 59.7 0.1 1.1e-15 57.6 0.0 2.1 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Band_3_cyto PF07565.8 EPS26648.1 - 1.1 8.7 6.8 1.7 8.0 4.7 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain ApbA PF02558.11 EPS26649.1 - 2.9e-24 85.2 0.0 1.2e-23 83.2 0.0 1.8 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EPS26649.1 - 7.6e-24 84.0 0.0 1.5e-23 83.1 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal F420_oxidored PF03807.12 EPS26649.1 - 0.12 12.8 0.0 22 5.5 0.0 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 EPS26649.1 - 0.12 12.0 0.0 0.59 9.8 0.0 1.9 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sin3_corepress PF08295.7 EPS26649.1 - 0.13 12.0 1.1 0.23 11.2 0.8 1.3 1 0 0 1 1 1 0 Sin3 family co-repressor SET PF00856.23 EPS26650.1 - 1.7e-21 77.2 0.0 2.7e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 SET domain Coq4 PF05019.8 EPS26651.1 - 1.9e-98 327.8 0.0 2.3e-98 327.5 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 dsDNA_bind PF01984.15 EPS26652.1 - 3.8e-34 116.8 16.2 4.4e-34 116.6 11.2 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain DUF4615 PF15393.1 EPS26652.1 - 0.091 12.9 2.5 0.092 12.9 1.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4615) Med4 PF10018.4 EPS26652.1 - 5.5 6.3 11.1 40 3.5 7.7 2.0 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Sec2p PF06428.6 EPS26653.1 - 6.2e-28 96.6 11.3 6.2e-28 96.6 7.8 2.0 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p Arb2 PF09757.4 EPS26653.1 - 0.0024 17.3 1.6 0.54 9.6 0.2 2.4 2 0 0 2 2 2 2 Arb2 domain V_ATPase_I PF01496.14 EPS26653.1 - 0.39 8.5 9.5 0.6 7.9 6.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CorA PF01544.13 EPS26653.1 - 1.8 7.5 8.5 3.1 6.7 5.9 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.7 EPS26653.1 - 9.2 6.0 12.3 17 5.2 1.9 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2076 PF09849.4 EPS26654.1 - 6.5e-12 46.0 8.7 8e-12 45.7 6.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 EPS26654.1 - 3.8e-05 23.4 1.2 6.2e-05 22.8 0.8 1.4 1 0 0 1 1 1 1 CHCH domain DUF2613 PF11021.3 EPS26654.1 - 2.7 7.7 9.9 0.55 9.9 3.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2613) DUF2413 PF10310.4 EPS26654.1 - 3.7 6.2 6.5 4.4 6.0 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) UBX PF00789.15 EPS26655.1 - 2.5e-09 37.0 0.0 5.5e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 UBX domain SURF1 PF02104.10 EPS26656.1 - 7.8e-65 218.6 0.0 1e-64 218.2 0.0 1.1 1 0 0 1 1 1 1 SURF1 family CENP-T PF15511.1 EPS26657.1 - 7.8e-98 328.4 9.6 1.4e-97 327.6 6.6 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T CENP-S PF15630.1 EPS26657.1 - 3.1e-08 33.6 0.0 5.5e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 EPS26657.1 - 0.00012 22.0 0.1 0.00023 21.1 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EPS26657.1 - 0.00073 19.5 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF531 PF04407.7 EPS26657.1 - 0.18 11.7 0.0 0.3 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF531) CMS1 PF14617.1 EPS26658.1 - 6.4e-83 277.6 5.6 9.2e-83 277.1 3.6 1.4 1 1 1 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 EPS26658.1 - 7.2e-05 22.3 0.0 7.2e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase RRM_1 PF00076.17 EPS26659.1 - 5.6e-12 45.1 1.1 1.3e-11 43.9 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS26659.1 - 7.8e-10 38.5 0.0 2.3e-09 37.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 EPS26659.1 - 0.3 9.5 72.0 0.081 11.3 42.7 2.0 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Ras PF00071.17 EPS26660.1 - 6.2e-55 184.9 0.0 7.2e-55 184.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPS26660.1 - 1e-17 64.7 0.0 1.4e-17 64.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPS26660.1 - 5.4e-07 29.0 0.0 7.1e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family ABM PF03992.11 EPS26661.1 - 2.7e-13 49.7 0.0 4.3e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Spt5-NGN PF03439.8 EPS26661.1 - 0.043 13.5 0.1 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Early transcription elongation factor of RNA pol II, NGN section RhoGAP PF00620.22 EPS26662.1 - 5.3e-49 165.7 0.0 1.5e-48 164.2 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 EPS26662.1 - 1.8e-14 53.6 2.2 2.2e-14 53.3 0.4 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain FUSC PF04632.7 EPS26662.1 - 1.7 6.9 9.7 2.6 6.3 6.7 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tropomyosin_1 PF12718.2 EPS26662.1 - 3.1 7.6 12.4 0.14 11.9 3.9 2.1 2 1 0 2 2 2 0 Tropomyosin like MBA1 PF07961.6 EPS26663.1 - 3.7e-08 32.5 0.1 5.8e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 MBA1-like protein Tim44 PF04280.10 EPS26663.1 - 0.11 12.4 0.8 0.31 11.0 0.5 1.7 1 1 0 1 1 1 0 Tim44-like domain EOS1 PF12326.3 EPS26664.1 - 6.6e-31 106.9 13.2 8e-26 90.4 5.9 2.1 1 1 1 2 2 2 2 N-glycosylation protein SUI1 PF01253.17 EPS26665.1 - 2.2e-29 101.0 6.2 2.9e-29 100.7 4.3 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Cas_Csa5 PF09702.5 EPS26665.1 - 0.1 12.7 0.7 0.29 11.2 0.1 1.8 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_Csa5) UPF0139 PF03669.8 EPS26666.1 - 4.3e-06 26.1 0.9 5.6e-06 25.8 0.7 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) Cons_hypoth698 PF03601.9 EPS26666.1 - 0.028 13.0 0.2 0.031 12.9 0.2 1.0 1 0 0 1 1 1 0 Conserved hypothetical protein 698 Med12 PF09497.5 EPS26667.1 - 7.1e-27 93.1 0.6 2.4e-26 91.5 0.4 2.0 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 RRM_1 PF00076.17 EPS26668.1 - 7.8e-10 38.2 0.0 2.8e-08 33.2 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS26668.1 - 5.5e-09 35.8 0.0 3.1e-07 30.2 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS26668.1 - 0.0014 18.4 0.0 0.0095 15.7 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CIA30 PF08547.7 EPS26669.1 - 2.2e-37 128.3 0.0 9.1e-24 84.0 0.0 2.1 2 0 0 2 2 2 2 Complex I intermediate-associated protein 30 (CIA30) SAICAR_synt PF01259.13 EPS26670.1 - 8.6e-87 290.3 0.0 1.1e-86 290.0 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase Apc5 PF12862.2 EPS26671.1 - 6.2e-33 112.5 5.5 1.8e-32 111.0 3.8 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.1 EPS26671.1 - 0.039 13.9 15.7 0.89 9.5 0.1 5.7 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 EPS26671.1 - 1.1 9.2 4.2 28 4.8 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat COX6A PF02046.10 EPS26672.1 - 4.6e-46 155.5 3.1 4.9e-46 155.3 2.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa Exo_endo_phos_2 PF14529.1 EPS26673.1 - 1.6e-13 50.2 0.0 2.8e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EPS26673.1 - 8.3e-11 42.2 0.0 1.3e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.7 EPS26673.1 - 0.00019 21.2 0.8 0.00047 20.0 0.6 1.7 1 0 0 1 1 1 1 GRF zinc finger HMG_box PF00505.14 EPS26675.1 - 6.1e-20 71.2 0.0 1e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EPS26675.1 - 0.00093 19.5 0.0 0.0015 18.8 0.0 1.3 1 0 0 1 1 1 1 HMG-box domain ANTH PF07651.11 EPS26676.1 - 1.2e-78 263.6 2.9 1.5e-78 263.3 0.0 2.5 2 0 0 2 2 2 1 ANTH domain I_LWEQ PF01608.12 EPS26676.1 - 4.9e-63 211.6 8.6 4.9e-63 211.6 6.0 5.8 4 2 3 7 7 7 1 I/LWEQ domain ENTH PF01417.15 EPS26676.1 - 0.00016 21.5 0.0 0.0012 18.6 0.0 2.6 2 0 0 2 2 2 1 ENTH domain NFRKB_winged PF14465.1 EPS26676.1 - 0.045 13.5 2.7 2.5 7.9 0.3 3.8 2 1 1 3 3 3 0 NFRKB Winged Helix-like DUF3682 PF12446.3 EPS26676.1 - 5.6 7.2 10.6 21 5.4 7.4 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) DUF2404 PF10296.4 EPS26677.1 - 3e-30 104.1 0.0 5.5e-30 103.3 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) polyprenyl_synt PF00348.12 EPS26678.1 - 9.1e-54 182.0 0.0 5.5e-51 172.9 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase HEPPP_synt_1 PF07307.6 EPS26678.1 - 0.055 12.9 0.1 0.083 12.3 0.0 1.2 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 TniQ PF06527.6 EPS26678.1 - 0.093 12.9 0.4 0.4 10.8 0.0 2.2 3 0 0 3 3 3 0 TniQ Rpn3_C PF08375.6 EPS26680.1 - 9.1e-25 86.8 0.6 9.1e-25 86.8 0.4 2.1 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 EPS26680.1 - 7.4e-20 71.2 1.1 4e-19 68.8 0.0 2.6 3 0 0 3 3 3 1 PCI domain PCI_Csn8 PF10075.4 EPS26680.1 - 0.0011 18.6 0.5 0.012 15.3 0.1 2.5 2 1 0 2 2 2 1 COP9 signalosome, subunit CSN8 DASH_Spc34 PF08657.5 EPS26681.1 - 5.9e-68 229.3 2.4 3e-66 223.7 1.7 2.0 1 1 0 1 1 1 1 DASH complex subunit Spc34 DUF465 PF04325.8 EPS26681.1 - 0.0013 18.4 1.1 0.0027 17.3 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF465) Myosin_tail_1 PF01576.14 EPS26681.1 - 0.0079 13.9 0.3 0.011 13.5 0.2 1.1 1 0 0 1 1 1 1 Myosin tail Prefoldin_2 PF01920.15 EPS26681.1 - 0.014 15.1 0.6 3.3 7.5 0.1 2.3 2 0 0 2 2 2 0 Prefoldin subunit DUF4140 PF13600.1 EPS26681.1 - 0.02 15.3 0.8 5.1 7.6 0.0 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) CENP-F_leu_zip PF10473.4 EPS26681.1 - 0.054 13.3 4.5 2.3 8.0 0.3 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DASH_Spc19 PF08287.6 EPS26681.1 - 0.089 12.4 0.3 0.15 11.6 0.2 1.3 1 0 0 1 1 1 0 Spc19 IncA PF04156.9 EPS26681.1 - 0.097 12.2 1.6 0.18 11.3 1.0 1.4 1 1 0 1 1 1 0 IncA protein Spectrin PF00435.16 EPS26681.1 - 0.11 12.8 0.1 16 5.8 0.0 2.3 2 0 0 2 2 2 0 Spectrin repeat TMF_DNA_bd PF12329.3 EPS26681.1 - 0.22 11.3 1.6 2.4 8.0 0.2 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 EPS26681.1 - 0.47 9.9 2.7 9.4 5.8 0.3 2.5 2 0 0 2 2 2 0 Septum formation initiator TFIID_20kDa PF03847.8 EPS26682.1 - 1.3e-22 79.8 0.0 2.2e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.19 EPS26682.1 - 0.015 15.3 0.0 0.034 14.2 0.0 1.6 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 DUF829 PF05705.9 EPS26683.1 - 2.1e-56 191.3 0.0 2.4e-56 191.1 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Glyco_hydro_76 PF03663.9 EPS26684.1 - 3.2e-114 382.1 18.1 4.3e-114 381.7 12.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 AA_permease_2 PF13520.1 EPS26685.1 - 8.4e-57 192.5 49.7 1e-56 192.3 34.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPS26685.1 - 4.2e-18 64.9 41.0 5.8e-18 64.4 28.4 1.1 1 0 0 1 1 1 1 Amino acid permease Gram_pos_anchor PF00746.16 EPS26685.1 - 0.23 11.2 0.0 0.23 11.2 0.0 3.8 5 0 0 5 5 5 0 Gram positive anchor DUF4243 PF14027.1 EPS26686.1 - 4.6e-89 299.1 3.3 5.5e-89 298.8 2.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Pro_CA PF00484.14 EPS26687.1 - 1.3e-48 164.8 0.1 1.7e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Pro_CA PF00484.14 EPS26688.1 - 8.5e-34 116.7 0.1 1e-33 116.5 0.0 1.0 1 0 0 1 1 1 1 Carbonic anhydrase ALIX_LYPXL_bnd PF13949.1 EPS26689.1 - 0.01 14.7 1.8 0.013 14.5 1.3 1.1 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV IncA PF04156.9 EPS26689.1 - 0.025 14.1 2.5 0.026 14.1 1.8 1.1 1 0 0 1 1 1 0 IncA protein DUF904 PF06005.7 EPS26689.1 - 0.35 11.1 4.5 0.59 10.4 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) HECT_2 PF09814.4 EPS26690.1 - 3e-81 272.9 0.0 3.4e-81 272.7 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding TauD PF02668.11 EPS26691.1 - 2.2e-54 184.8 0.3 2.8e-54 184.4 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 EPS26692.1 - 6.9e-23 80.9 19.3 6.9e-23 80.9 13.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EPS26692.1 - 0.051 13.3 2.6 0.054 13.3 0.3 2.2 2 0 0 2 2 2 0 MFS_1 like family Cupin_2 PF07883.6 EPS26693.1 - 0.058 12.9 0.2 0.08 12.4 0.2 1.2 1 0 0 1 1 1 0 Cupin domain zf-Apc11 PF12861.2 EPS26694.1 - 0.37 10.6 4.9 0.47 10.3 3.4 1.4 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PI-PLC-X PF00388.14 EPS26696.1 - 4.7e-58 194.7 0.0 9.7e-58 193.7 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EPS26696.1 - 6.6e-36 122.8 0.2 1.5e-35 121.7 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain GST_N_3 PF13417.1 EPS26697.1 - 1e-08 35.2 0.0 1.9e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EPS26697.1 - 6.7e-05 22.6 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EPS26697.1 - 0.0017 18.2 0.0 0.0032 17.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EPS26697.1 - 0.022 15.2 0.0 0.035 14.5 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EPS26697.1 - 0.068 13.1 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ribosomal_L37 PF08561.5 EPS26698.1 - 2.8e-28 97.2 6.5 3.6e-27 93.7 4.5 2.2 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 LELP1 PF15042.1 EPS26698.1 - 0.66 10.1 7.5 2.4 8.3 4.5 2.1 2 0 0 2 2 2 0 Late cornified envelope-like proline-rich protein 1 Epimerase PF01370.16 EPS26699.1 - 8.1e-35 120.3 0.0 1.6e-34 119.3 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EPS26699.1 - 3.1e-12 46.2 0.1 6e-12 45.3 0.1 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit Polysacc_synt_2 PF02719.10 EPS26699.1 - 2.7e-07 29.7 0.0 1.5e-05 24.0 0.0 2.4 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EPS26699.1 - 3.6e-06 25.9 0.0 4.9e-05 22.1 0.0 2.5 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EPS26699.1 - 4e-06 25.9 0.1 3.6e-05 22.8 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EPS26699.1 - 2.7e-05 24.1 0.0 4.5e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPS26699.1 - 0.00027 20.6 0.0 0.00049 19.8 0.0 1.4 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 EPS26699.1 - 0.00043 19.2 0.0 0.0064 15.4 0.0 2.6 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EPS26699.1 - 0.077 12.9 0.0 1 9.3 0.0 2.7 2 1 1 3 3 3 0 NADH(P)-binding SKI PF01202.17 EPS26699.1 - 0.085 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate kinase UDPG_MGDP_dh_N PF03721.9 EPS26699.1 - 0.14 11.5 0.1 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Spherulin4 PF12138.3 EPS26700.1 - 2e-74 250.2 0.0 2.3e-74 250.0 0.0 1.0 1 0 0 1 1 1 1 Spherulation-specific family 4 Glyco_hydro_114 PF03537.8 EPS26701.1 - 1.5e-26 91.9 0.1 2.7e-26 91.1 0.1 1.4 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Polysacc_deac_1 PF01522.16 EPS26703.1 - 0.057 13.0 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 Polysaccharide deacetylase Glycos_transf_1 PF00534.15 EPS26705.1 - 4.1e-12 45.8 0.0 7.3e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3492 PF11997.3 EPS26705.1 - 1.4e-05 24.7 0.0 0.00013 21.6 0.0 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3492) Glyco_trans_1_4 PF13692.1 EPS26705.1 - 5.3e-05 23.3 0.0 0.00026 21.1 0.0 2.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 DPPIV_N PF00930.16 EPS26706.1 - 1.1e-110 369.5 0.2 1.5e-110 369.1 0.2 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EPS26706.1 - 1.8e-54 184.2 0.8 3e-54 183.4 0.6 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EPS26706.1 - 2.2e-09 37.1 0.0 4.5e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPS26706.1 - 7.4e-06 26.0 0.0 0.00013 21.9 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EPS26706.1 - 5.7e-05 22.6 0.6 0.00019 20.9 0.1 1.9 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 EPS26706.1 - 0.014 13.9 0.0 0.15 10.5 0.0 2.2 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Peptidase_S10 PF00450.17 EPS26706.1 - 0.019 14.1 0.0 0.3 10.2 0.1 2.1 2 0 0 2 2 2 0 Serine carboxypeptidase PAF-AH_p_II PF03403.8 EPS26706.1 - 0.025 12.8 0.0 1.5 7.0 0.0 2.1 1 1 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II CHB_HEX PF03173.8 EPS26706.1 - 0.061 12.7 0.0 0.17 11.3 0.0 1.7 2 0 0 2 2 2 0 Putative carbohydrate binding domain DLH PF01738.13 EPS26706.1 - 0.068 12.4 0.0 0.53 9.5 0.0 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydro_lipase PF04083.11 EPS26706.1 - 0.099 12.0 0.1 0.49 9.7 0.0 2.2 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region BAAT_C PF08840.6 EPS26706.1 - 0.16 11.6 0.0 13 5.3 0.0 2.3 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Zn_clus PF00172.13 EPS26707.1 - 1.7e-09 37.4 9.1 3e-09 36.6 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EPS26707.1 - 1.2e-05 24.1 0.1 1.7e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain C5-epim_C PF06662.8 EPS26707.1 - 0.078 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus Cpn60_TCP1 PF00118.19 EPS26708.1 - 7.2e-139 463.5 9.4 9e-139 463.2 6.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.7 EPS26708.1 - 0.028 13.9 0.0 0.068 12.6 0.0 1.6 1 0 0 1 1 1 0 Phage Tail Protein X GTP1_OBG PF01018.17 EPS26708.1 - 0.07 12.7 0.1 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 GTP1/OBG AAA PF00004.24 EPS26709.1 - 2.4e-40 137.7 0.0 4.1e-40 137.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPS26709.1 - 5.1e-06 26.6 0.0 0.00061 19.9 0.0 2.7 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EPS26709.1 - 4.9e-05 23.0 0.1 0.00028 20.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EPS26709.1 - 0.00028 20.9 0.0 0.0012 18.8 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 EPS26709.1 - 0.00043 20.2 0.0 0.0013 18.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EPS26709.1 - 0.0017 17.3 0.0 0.0029 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EPS26709.1 - 0.004 17.9 0.1 0.012 16.4 0.1 2.0 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EPS26709.1 - 0.0099 14.9 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EPS26709.1 - 0.01 15.5 0.1 0.021 14.5 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 EPS26709.1 - 0.018 14.9 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EPS26709.1 - 0.023 14.6 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EPS26709.1 - 0.035 13.9 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EPS26709.1 - 0.042 13.4 0.1 0.61 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EPS26709.1 - 0.049 13.7 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 EPS26709.1 - 0.065 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EPS26709.1 - 0.072 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Sigma54_activ_2 PF14532.1 EPS26709.1 - 0.099 12.6 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 EPS26709.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EPS26709.1 - 0.14 11.5 0.2 0.48 9.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain FAD_binding_2 PF00890.19 EPS26710.1 - 1.3e-126 422.8 3.8 1.9e-126 422.3 2.6 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EPS26710.1 - 6.1e-47 158.6 1.6 9e-47 158.1 1.1 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EPS26710.1 - 7.1e-08 32.5 0.0 0.0016 18.3 0.1 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EPS26710.1 - 2.5e-05 23.3 1.2 0.02 13.7 1.3 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.12 EPS26710.1 - 2.5e-05 23.4 0.2 0.013 14.5 0.0 2.3 2 0 0 2 2 2 2 Thi4 family DAO PF01266.19 EPS26710.1 - 5.9e-05 22.1 0.2 0.00099 18.1 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EPS26710.1 - 0.0046 16.0 0.2 0.0094 15.0 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain PAPS_reduct PF01507.14 EPS26710.1 - 0.13 12.1 0.4 0.21 11.3 0.3 1.2 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family HI0933_like PF03486.9 EPS26710.1 - 0.31 9.4 2.1 0.61 8.4 0.5 2.1 3 0 0 3 3 3 0 HI0933-like protein Shisa PF13908.1 EPS26711.1 - 0.0027 17.9 5.9 0.0043 17.2 0.0 2.4 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator Adeno_E3_CR2 PF02439.10 EPS26711.1 - 0.0061 16.0 0.3 0.011 15.2 0.2 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Herpes_gE PF02480.11 EPS26711.1 - 0.035 12.3 0.0 0.056 11.6 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Lyase_1 PF00206.15 EPS26712.1 - 1.5e-90 303.5 0.0 2.3e-90 302.9 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 EPS26712.1 - 1e-26 92.7 0.1 2.9e-26 91.3 0.1 1.8 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Membralin PF09746.4 EPS26712.1 - 0.13 11.2 0.0 0.37 9.7 0.0 1.6 1 1 1 2 2 2 0 Tumour-associated protein FR47 PF08445.5 EPS26713.1 - 3e-06 26.9 0.0 0.0037 17.0 0.0 2.3 2 0 0 2 2 2 2 FR47-like protein Acetyltransf_3 PF13302.1 EPS26713.1 - 0.00038 20.6 0.1 0.0006 19.9 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPS26713.1 - 0.0034 17.3 0.1 0.0079 16.2 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EPS26713.1 - 0.017 15.2 0.0 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain IBD PF10416.4 EPS26715.1 - 0.02 14.6 0.5 0.031 14.0 0.3 1.3 1 0 0 1 1 1 0 Transcription-initiator DNA-binding domain IBD Terpene_synth_C PF03936.11 EPS26717.1 - 1.7e-11 43.9 0.1 2.4e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Herpes_pp38 PF04846.8 EPS26718.1 - 0.058 12.7 0.3 0.11 11.7 0.2 1.4 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein RRM_1 PF00076.17 EPS26719.1 - 2.2e-44 148.9 0.0 1.5e-21 75.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS26719.1 - 3.7e-37 126.1 0.0 6e-18 64.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS26719.1 - 4.9e-22 77.5 0.0 6.1e-10 38.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Alg6_Alg8 PF03155.10 EPS26720.1 - 8e-128 427.2 21.1 4.3e-82 276.4 6.2 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family COX17 PF05051.8 EPS26721.1 - 9e-22 76.8 6.0 1.4e-21 76.2 4.2 1.3 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 EPS26721.1 - 0.01 15.5 3.0 0.3 10.9 0.0 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like LRR_6 PF13516.1 EPS26722.1 - 2.5e-09 36.2 4.0 0.015 15.3 0.0 6.5 8 0 0 8 8 8 3 Leucine Rich repeat LRR_4 PF12799.2 EPS26722.1 - 6.2e-07 28.9 4.9 0.034 13.7 0.0 5.2 4 2 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPS26722.1 - 0.00016 21.1 2.8 20 5.7 0.0 6.0 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_8 PF13855.1 EPS26722.1 - 0.34 10.7 8.4 3.2 7.5 0.0 4.4 4 2 0 4 4 4 0 Leucine rich repeat SDA1 PF05285.7 EPS26722.1 - 0.56 9.4 18.9 0.99 8.6 13.1 1.4 1 0 0 1 1 1 0 SDA1 Mpp10 PF04006.7 EPS26722.1 - 0.79 8.0 21.4 1.2 7.4 14.8 1.2 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.7 EPS26722.1 - 8.2 4.2 21.4 11 3.7 14.8 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIS_M PF07500.9 EPS26723.1 - 3.4e-26 91.5 1.9 7.9e-26 90.3 0.1 2.1 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 EPS26723.1 - 4.1e-19 67.9 5.3 7.3e-19 67.1 3.7 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 EPS26723.1 - 6.3e-14 51.2 0.3 1.8e-13 49.7 0.2 1.8 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Baculo_LEF5_C PF11792.3 EPS26723.1 - 0.0049 16.2 1.6 0.012 14.9 1.1 1.7 1 1 0 1 1 1 1 Baculoviridae late expression factor 5 C-terminal domain Chordopox_A33R PF05966.7 EPS26723.1 - 0.061 12.0 0.0 0.14 10.9 0.0 1.6 1 0 0 1 1 1 0 Chordopoxvirus A33R protein ABC1 PF03109.11 EPS26725.1 - 7.5e-22 77.5 0.1 7.1e-21 74.3 0.0 2.3 2 0 0 2 2 2 1 ABC1 family APH PF01636.18 EPS26725.1 - 0.0043 16.8 0.7 0.04 13.6 0.5 2.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family DNA_processg_A PF02481.10 EPS26725.1 - 0.14 11.0 0.1 0.39 9.5 0.0 1.7 2 0 0 2 2 2 0 DNA recombination-mediator protein A CO_deh_flav_C PF03450.12 EPS26726.1 - 0.12 12.3 0.0 0.67 9.9 0.0 2.0 2 0 0 2 2 2 0 CO dehydrogenase flavoprotein C-terminal domain Lactamase_B PF00753.22 EPS26727.1 - 2.2e-08 33.9 1.0 1.6e-06 27.8 0.2 2.2 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EPS26727.1 - 0.00098 18.7 0.1 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Abhydrolase_2 PF02230.11 EPS26733.1 - 0.065 12.6 0.0 0.075 12.4 0.0 1.0 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase E1-E2_ATPase PF00122.15 EPS26735.1 - 3.5e-69 232.3 1.3 3.5e-69 232.3 0.9 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EPS26735.1 - 1.5e-23 84.3 0.5 4.3e-23 82.8 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EPS26735.1 - 3.6e-13 50.1 0.0 9.3e-13 48.7 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EPS26735.1 - 6e-11 41.6 0.4 1.7e-10 40.2 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EPS26735.1 - 0.0017 17.9 0.1 0.0034 16.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPS26735.1 - 0.021 14.7 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit DMA PF03474.9 EPS26735.1 - 0.094 12.5 0.2 2.6 7.9 0.0 2.5 2 0 0 2 2 2 0 DMRTA motif Pectinesterase PF01095.14 EPS26736.1 - 1.2e-29 102.8 2.8 8.9e-23 80.2 0.2 2.1 2 0 0 2 2 2 2 Pectinesterase LXG PF04740.7 EPS26738.1 - 0.49 10.1 0.5 0.83 9.3 0.3 1.2 1 0 0 1 1 1 0 LXG domain of WXG superfamily SNARE PF05739.14 EPS26739.1 - 1.1e-17 63.4 3.1 3e-17 62.0 0.6 2.7 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EPS26739.1 - 2.6e-15 56.4 3.0 9.5e-15 54.6 0.1 2.6 2 1 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 EPS26739.1 - 0.0062 16.1 1.5 0.0062 16.1 1.0 2.3 2 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Sed5p PF11416.3 EPS26739.1 - 0.075 12.4 0.1 0.18 11.2 0.1 1.6 1 0 0 1 1 1 0 Integral membrane protein Sed5p zf-C4H2 PF10146.4 EPS26739.1 - 0.091 12.7 1.7 0.97 9.4 0.1 2.2 1 1 1 2 2 2 0 Zinc finger-containing protein NPV_P10 PF05531.7 EPS26739.1 - 0.1 12.8 3.6 10 6.4 0.1 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein LTXXQ PF07813.7 EPS26739.1 - 1.3 9.5 11.9 0.87 10.0 0.1 3.6 3 2 2 5 5 5 0 LTXXQ motif family protein HAUS-augmin3 PF14932.1 EPS26739.1 - 1.8 7.6 9.1 0.55 9.3 1.2 2.4 2 1 0 2 2 2 0 HAUS augmin-like complex subunit 3 SlyX PF04102.7 EPS26739.1 - 2.5 8.5 5.1 16 5.9 0.1 3.0 2 0 0 2 2 2 0 SlyX Fungal_trans PF04082.13 EPS26740.1 - 3.5e-21 75.2 0.0 1.1e-20 73.5 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS26740.1 - 4.6e-10 39.2 10.0 1.2e-09 37.9 6.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 EPS26741.1 - 1.7e-77 260.8 0.0 2.1e-77 260.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EPS26741.1 - 0.00014 22.2 0.1 0.022 15.1 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPS26741.1 - 0.00028 20.0 0.0 0.00054 19.1 0.0 1.4 1 0 0 1 1 1 1 Thi4 family SE PF08491.5 EPS26741.1 - 0.00033 19.5 0.0 0.00049 19.0 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.9 EPS26741.1 - 0.0019 18.1 0.0 0.0042 17.0 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EPS26741.1 - 0.0024 16.4 0.1 0.032 12.6 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.7 EPS26741.1 - 0.0029 16.5 0.0 0.0051 15.7 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EPS26741.1 - 0.0037 17.2 0.0 0.011 15.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EPS26741.1 - 0.0037 16.2 0.4 0.0083 15.0 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPS26741.1 - 0.0073 15.2 0.0 0.015 14.1 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EPS26741.1 - 0.069 13.1 0.0 0.22 11.5 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EPS26742.1 - 2.4e-27 95.9 0.0 5e-27 94.8 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EPS26742.1 - 9.8e-09 34.5 0.2 0.003 16.5 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPS26742.1 - 2.6e-05 24.1 0.2 6.8e-05 22.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EPS26742.1 - 0.00012 22.3 0.1 0.13 12.7 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EPS26742.1 - 0.00021 20.3 0.1 0.38 9.6 0.1 2.3 3 0 0 3 3 3 2 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EPS26742.1 - 0.00029 20.9 0.0 0.00057 19.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EPS26742.1 - 0.00031 19.7 0.1 0.016 14.0 0.1 2.1 1 1 1 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EPS26742.1 - 0.00049 18.6 0.1 0.41 9.0 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Amino_oxidase PF01593.19 EPS26742.1 - 0.0044 16.1 0.0 0.82 8.6 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 EPS26742.1 - 0.017 14.8 0.3 0.26 11.0 0.1 2.8 4 0 0 4 4 4 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EPS26742.1 - 0.03 14.1 0.1 0.097 12.5 0.0 1.8 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EPS26742.1 - 0.054 12.3 0.0 1.1 8.0 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Thi4 PF01946.12 EPS26742.1 - 0.073 12.1 0.1 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Thi4 family NAD_Gly3P_dh_N PF01210.18 EPS26742.1 - 0.093 12.4 0.0 0.27 10.9 0.0 1.7 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ArsB PF02040.10 EPS26745.1 - 4.2e-13 49.0 23.0 2.9e-09 36.3 6.7 2.3 2 0 0 2 2 2 2 Arsenical pump membrane protein Mannosyl_trans3 PF11051.3 EPS26746.1 - 6.6e-82 274.9 0.0 1.3e-81 273.9 0.0 1.5 1 1 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_34 PF05637.7 EPS26748.1 - 1.9e-55 187.9 1.6 2.3e-55 187.7 1.1 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Acyl_transf_3 PF01757.17 EPS26749.1 - 2.2e-21 76.0 32.0 3.8e-21 75.2 22.2 1.4 1 1 0 1 1 1 1 Acyltransferase family DUF1624 PF07786.7 EPS26749.1 - 0.00066 19.0 11.6 0.015 14.6 4.9 3.4 1 1 0 2 2 2 2 Protein of unknown function (DUF1624) Peptidase_M24 PF00557.19 EPS26749.1 - 0.065 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Metallopeptidase family M24 p450 PF00067.17 EPS26750.1 - 2e-78 263.9 0.0 2.5e-78 263.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 EPS26750.1 - 5.2e-31 107.7 0.0 8.3e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EPS26750.1 - 4.9e-29 101.1 0.0 1.9e-27 96.0 0.0 2.4 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 EPS26750.1 - 4.8e-12 46.4 0.0 1.7e-11 44.6 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EPS26750.1 - 0.00062 19.7 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin domain Glyco_hydro_16 PF00722.16 EPS26751.1 - 1.3e-38 132.1 6.3 1.3e-38 132.1 4.4 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 RCR PF12273.3 EPS26751.1 - 0.05 14.1 0.0 0.14 12.7 0.0 1.7 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red SMC_N PF02463.14 EPS26753.1 - 1.3e-74 250.2 19.0 8.7e-74 247.4 13.2 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EPS26753.1 - 4.9e-28 97.5 0.0 2e-27 95.5 0.0 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EPS26753.1 - 5.3e-10 39.7 14.1 9.9e-05 22.4 1.8 3.7 2 2 0 2 2 2 2 AAA domain Reo_sigmaC PF04582.7 EPS26753.1 - 6.8e-05 22.2 0.9 6.8e-05 22.2 0.6 4.6 2 2 3 5 5 5 1 Reovirus sigma C capsid protein AAA_29 PF13555.1 EPS26753.1 - 0.0001 21.7 0.0 0.00023 20.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EPS26753.1 - 0.0011 19.3 28.4 0.0011 19.3 19.7 7.4 2 2 3 5 5 5 1 AAA domain Bacillus_HBL PF05791.6 EPS26753.1 - 0.15 11.4 56.8 0.024 14.0 1.6 6.4 4 1 2 6 6 6 0 Bacillus haemolytic enterotoxin (HBL) DUF948 PF06103.6 EPS26753.1 - 1.8 8.4 26.8 2 8.3 0.4 5.8 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) ELYS PF13934.1 EPS26754.1 - 7.8e-74 248.2 0.0 9.3e-74 247.9 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore complex assembly zf-CCCH PF00642.19 EPS26755.1 - 1.7e-06 27.5 2.7 3.7e-06 26.4 1.9 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EPS26755.1 - 0.076 13.0 4.3 0.17 11.9 2.9 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Ribosomal_S10 PF00338.17 EPS26756.1 - 2.2e-27 94.7 0.5 2.7e-27 94.4 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e CUE PF02845.11 EPS26757.1 - 1.9e-06 27.2 0.1 4e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 CUE domain FA_desaturase PF00487.19 EPS26758.1 - 4.4e-37 127.9 26.9 6.4e-37 127.3 18.7 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EPS26758.1 - 4.7e-13 48.7 0.0 1e-12 47.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PGM_PMM_I PF02878.11 EPS26759.1 - 4.8e-32 110.3 0.1 8.8e-32 109.4 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EPS26759.1 - 2.9e-20 72.5 0.0 6.8e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 EPS26759.1 - 1.4e-14 54.0 0.2 2.8e-14 53.1 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 EPS26759.1 - 3.7e-09 36.4 0.0 1e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain MFS_1 PF07690.11 EPS26760.1 - 3.8e-31 108.0 54.1 9.1e-31 106.8 35.3 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EPS26760.1 - 3.5e-14 51.9 9.2 3.5e-14 51.9 6.4 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EPS26760.1 - 5e-10 38.5 30.3 1.6e-07 30.2 9.8 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 EPS26760.1 - 2.3e-07 29.5 2.4 2.3e-07 29.5 1.7 2.9 3 2 0 3 3 3 1 MFS/sugar transport protein SKG6 PF08693.5 EPS26760.1 - 0.48 9.7 4.6 0.93 8.8 1.5 2.7 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Pyr_redox_dim PF02852.17 EPS26761.1 - 2.1e-40 137.1 0.2 6.6e-40 135.5 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 EPS26761.1 - 1.1e-38 133.2 13.8 7.3e-37 127.2 9.5 4.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPS26761.1 - 1.2e-22 80.0 10.8 6e-21 74.6 0.8 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPS26761.1 - 4.1e-10 40.0 0.2 5.9e-07 29.7 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EPS26761.1 - 4.4e-10 39.2 11.1 5.1e-10 38.9 0.2 3.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPS26761.1 - 1.7e-09 37.5 5.6 7.8e-05 22.6 0.5 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EPS26761.1 - 1.2e-07 30.9 13.9 1.3e-06 27.5 2.7 3.0 2 2 1 3 3 3 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EPS26761.1 - 4.6e-07 29.0 3.8 4.6e-07 29.0 2.6 2.7 3 1 0 3 3 3 1 FAD binding domain Thi4 PF01946.12 EPS26761.1 - 7.2e-07 28.5 5.9 1.1e-05 24.6 0.2 2.5 2 0 0 2 2 2 2 Thi4 family DAO PF01266.19 EPS26761.1 - 1.8e-06 27.0 22.2 0.00095 18.1 1.5 4.0 2 2 1 4 4 4 3 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EPS26761.1 - 6.8e-06 25.7 3.2 0.002 17.6 0.1 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 EPS26761.1 - 7.7e-06 24.6 15.4 0.0006 18.3 1.4 4.1 4 0 0 4 4 4 2 HI0933-like protein K_oxygenase PF13434.1 EPS26761.1 - 2.6e-05 23.3 0.4 0.077 11.8 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 EPS26761.1 - 0.0083 15.0 2.4 0.11 11.3 0.0 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 EPS26761.1 - 0.014 14.4 12.0 0.18 10.8 0.8 3.1 2 1 0 2 2 2 0 FAD binding domain 3HCDH_N PF02737.13 EPS26761.1 - 0.022 14.3 1.3 0.022 14.3 0.9 2.6 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 EPS26761.1 - 0.031 13.3 1.0 0.68 9.0 0.0 3.1 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glucodextran_N PF09137.6 EPS26761.1 - 0.032 13.4 0.0 0.051 12.8 0.0 1.2 1 0 0 1 1 1 0 Glucodextranase, domain N Amino_oxidase PF01593.19 EPS26761.1 - 0.064 12.3 0.1 0.14 11.2 0.1 1.4 1 1 0 1 1 1 0 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.1 EPS26761.1 - 0.13 12.5 4.6 0.23 11.7 0.1 2.9 2 1 0 2 2 2 0 Putative NAD(P)-binding FMO-like PF00743.14 EPS26761.1 - 0.44 8.6 4.7 0.76 7.8 0.7 2.6 2 1 2 4 4 4 0 Flavin-binding monooxygenase-like Trp_halogenase PF04820.9 EPS26761.1 - 1.4 7.4 7.6 1 7.9 0.6 2.3 2 0 0 2 2 2 0 Tryptophan halogenase Nitroreductase PF00881.19 EPS26762.1 - 3.4e-11 43.2 0.0 4.4e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family Abhydrolase_3 PF07859.8 EPS26763.1 - 1.9e-27 96.2 0.0 2.7e-27 95.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EPS26763.1 - 3.4e-10 39.1 0.0 5.2e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EPS26763.1 - 0.0007 19.3 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Sugar_tr PF00083.19 EPS26765.1 - 9.7e-83 278.2 23.0 1.1e-82 278.0 15.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS26765.1 - 1.1e-20 73.7 49.4 9.2e-17 60.7 11.5 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EPS26765.1 - 0.14 12.1 8.5 2.4 8.2 0.1 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1228) Rick_17kDa_Anti PF05433.10 EPS26765.1 - 0.44 10.2 5.6 1.5 8.5 3.9 1.9 1 0 0 1 1 1 0 Glycine zipper 2TM domain DNA_binding_1 PF01035.15 EPS26766.1 - 2e-27 94.7 0.2 3.3e-27 94.0 0.1 1.4 1 1 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain zf-C2H2_4 PF13894.1 EPS26767.1 - 1.1e-05 25.4 7.7 0.0021 18.2 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EPS26767.1 - 5.8e-05 23.1 9.7 0.0033 17.6 0.4 2.8 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EPS26767.1 - 0.086 12.7 3.7 0.93 9.4 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Not3 PF04065.10 EPS26770.1 - 1.2e-95 319.1 21.4 1.7e-95 318.7 14.8 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EPS26770.1 - 7.4e-44 148.8 10.3 1.9e-43 147.5 7.2 1.8 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Cep57_MT_bd PF06657.8 EPS26770.1 - 0.0004 20.2 5.2 0.048 13.6 0.1 2.8 2 0 0 2 2 2 2 Centrosome microtubule-binding domain of Cep57 DUF2373 PF10180.4 EPS26770.1 - 0.008 15.7 3.9 0.02 14.4 2.7 1.7 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Snapin_Pallidin PF14712.1 EPS26770.1 - 0.019 15.2 11.8 0.11 12.8 1.3 2.5 2 0 0 2 2 2 0 Snapin/Pallidin DUF1192 PF06698.6 EPS26770.1 - 0.35 10.7 4.0 0.27 11.0 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Syntaxin_2 PF14523.1 EPS26770.1 - 6.9 6.7 9.4 0.36 10.8 2.2 2.1 2 1 0 2 2 2 0 Syntaxin-like protein Syntaxin PF00804.20 EPS26770.1 - 8.6 6.5 15.3 1.4e+03 -0.6 11.1 3.1 2 1 0 2 2 2 0 Syntaxin Tyr_Deacylase PF02580.11 EPS26771.1 - 1.8e-46 157.7 0.0 2.3e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase DUF29 PF01724.11 EPS26771.1 - 0.046 13.5 0.0 0.085 12.7 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function DUF29 Pro_isomerase PF00160.16 EPS26772.1 - 7.3e-46 156.2 1.3 1.1e-45 155.6 0.9 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 EPS26772.1 - 6.4e-10 38.5 5.5 9.8e-05 21.9 0.2 2.3 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EPS26772.1 - 5.6e-06 25.8 0.7 5.6e-06 25.8 0.5 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EPS26772.1 - 1.2e-05 25.1 8.6 5.4e-05 23.0 4.6 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EPS26772.1 - 1.6e-05 24.2 0.3 1.6e-05 24.2 0.2 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EPS26772.1 - 0.0015 18.1 0.2 0.0015 18.1 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EPS26772.1 - 0.17 12.6 10.0 0.91 10.2 6.5 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EPS26772.1 - 0.84 10.4 5.6 0.27 11.9 0.6 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat DAO PF01266.19 EPS26773.1 - 4.7e-52 177.0 0.0 6.1e-52 176.6 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase ThiF PF00899.16 EPS26773.1 - 1.9e-05 24.4 0.0 4.7e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 ThiF family FAD_binding_2 PF00890.19 EPS26773.1 - 4.2e-05 22.5 0.1 0.00013 20.9 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EPS26773.1 - 7.7e-05 22.6 0.0 0.16 11.8 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EPS26773.1 - 0.00035 19.5 0.0 0.46 9.2 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A 3HCDH_N PF02737.13 EPS26773.1 - 0.0014 18.3 0.0 0.15 11.6 0.0 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 EPS26773.1 - 0.0033 17.4 0.0 0.0088 16.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_Gly3P_dh_N PF01210.18 EPS26773.1 - 0.0074 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_3 PF01494.14 EPS26773.1 - 0.02 13.9 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 EPS26773.1 - 0.044 14.1 0.0 0.2 12.0 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPS26773.1 - 0.049 13.4 0.1 0.54 10.0 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EPS26773.1 - 0.1 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FmdA_AmdA PF03069.10 EPS26774.1 - 2.8e-159 529.7 0.0 3.2e-159 529.5 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family EI24 PF07264.6 EPS26775.1 - 5.8e-05 22.6 2.8 5.8e-05 22.6 1.9 3.0 1 1 1 2 2 2 2 Etoposide-induced protein 2.4 (EI24) Inp1 PF12634.2 EPS26776.1 - 7.2e-31 106.8 0.1 3.1e-30 104.7 0.0 2.1 2 0 0 2 2 2 1 Inheritance of peroxisomes protein 1 SOBP PF15279.1 EPS26776.1 - 2.4 8.4 14.3 4.7 7.4 9.9 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein AMP-binding PF00501.23 EPS26777.1 - 2.9e-81 273.0 0.0 3.8e-81 272.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPS26777.1 - 3.2e-16 60.0 0.1 1e-15 58.4 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Transferase PF02458.10 EPS26777.1 - 4.9e-07 28.5 0.0 7.7e-07 27.8 0.0 1.2 1 0 0 1 1 1 1 Transferase family SUKH-3 PF14433.1 EPS26777.1 - 0.04 13.6 0.0 0.079 12.7 0.0 1.4 1 0 0 1 1 1 0 SUKH-3 immunity protein TRI5 PF06330.6 EPS26778.1 - 5.1e-29 101.0 1.8 6.8e-29 100.6 1.3 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) polyprenyl_synt PF00348.12 EPS26779.1 - 3.9e-59 199.6 0.0 5.2e-59 199.2 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase p450 PF00067.17 EPS26780.1 - 5.8e-24 84.4 0.0 8e-23 80.6 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 SRP14 PF02290.10 EPS26781.1 - 1.3e-22 79.4 0.0 1.5e-21 76.0 0.0 2.1 1 1 0 1 1 1 1 Signal recognition particle 14kD protein MA3 PF02847.12 EPS26782.1 - 9.5e-21 73.6 0.0 4e-20 71.6 0.0 2.1 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.14 EPS26782.1 - 1.3e-20 73.7 0.3 8.5e-20 71.0 0.0 2.2 2 0 0 2 2 2 1 MIF4G domain DUF2611 PF11022.3 EPS26782.1 - 0.54 10.3 3.9 4.7 7.3 1.4 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2611) MFS_1 PF07690.11 EPS26784.1 - 3.2e-50 170.8 52.7 7.7e-50 169.5 36.5 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EPS26784.1 - 4.8e-18 64.6 16.6 4.8e-18 64.6 11.5 2.7 1 1 3 4 4 4 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EPS26784.1 - 1.4e-11 43.6 12.6 1.4e-11 43.6 8.8 3.1 1 1 3 4 4 4 1 Sugar (and other) transporter MFS_3 PF05977.8 EPS26784.1 - 7.4e-05 21.0 14.9 0.0028 15.8 3.9 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector Orthopox_A43R PF06517.6 EPS26784.1 - 0.033 13.7 0.3 0.074 12.6 0.2 1.5 1 0 0 1 1 1 0 Orthopoxvirus A43R protein Phytase-like PF13449.1 EPS26785.1 - 6.8e-30 104.4 0.0 1.8e-29 103.0 0.0 1.7 1 1 0 1 1 1 1 Esterase-like activity of phytase SdiA-regulated PF06977.6 EPS26785.1 - 0.11 11.4 0.0 2.8 6.8 0.0 2.5 3 0 0 3 3 3 0 SdiA-regulated Coatomer_WDAD PF04053.9 EPS26788.1 - 1.7e-152 508.2 0.0 5.5e-152 506.6 0.0 1.7 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.6 EPS26788.1 - 9e-92 307.8 0.0 1.3e-91 307.3 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 EPS26788.1 - 1.2e-52 173.9 12.9 2.4e-09 36.7 0.0 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 EPS26788.1 - 0.0051 15.0 7.0 1.5 6.8 0.0 4.0 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Evr1_Alr PF04777.8 EPS26789.1 - 5.7e-27 93.4 3.2 5.7e-27 93.4 2.2 2.0 2 1 0 2 2 2 1 Erv1 / Alr family Bd3614-deam PF14439.1 EPS26789.1 - 0.062 13.1 0.0 3.5 7.4 0.0 2.2 2 0 0 2 2 2 0 Bd3614-like deaminase Ank_2 PF12796.2 EPS26791.1 - 5.8e-10 39.3 0.0 1.7e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EPS26791.1 - 1.7e-09 36.9 0.0 3.7e-06 26.4 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat NACHT PF05729.7 EPS26791.1 - 2e-07 30.7 0.0 5.6e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EPS26791.1 - 2.5e-06 27.6 2.7 9.1e-06 25.7 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EPS26791.1 - 3.2e-06 27.3 0.5 6.8e-05 23.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain Ank_3 PF13606.1 EPS26791.1 - 8.2e-06 25.5 0.0 0.04 14.1 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat NB-ARC PF00931.17 EPS26791.1 - 1.5e-05 24.0 0.0 8.8e-05 21.5 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain Ank_5 PF13857.1 EPS26791.1 - 6.3e-05 23.0 0.0 0.024 14.9 0.0 2.8 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EPS26791.1 - 0.00014 22.2 0.0 0.00059 20.2 0.0 2.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) AAA_14 PF13173.1 EPS26791.1 - 0.00022 21.1 0.1 0.0011 18.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 EPS26791.1 - 0.0067 16.1 0.0 0.13 11.9 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 EPS26791.1 - 0.012 15.3 0.0 0.034 13.9 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 EPS26791.1 - 0.028 14.2 2.9 0.1 12.5 0.2 3.1 3 1 0 3 3 3 0 AAA domain AAA_29 PF13555.1 EPS26791.1 - 0.03 13.8 0.1 0.13 11.7 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_25 PF13481.1 EPS26791.1 - 0.032 13.6 0.0 0.098 12.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EPS26791.1 - 0.035 13.6 0.0 0.088 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EPS26791.1 - 0.037 13.7 0.0 0.08 12.6 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA_17 PF13207.1 EPS26791.1 - 0.071 13.9 1.0 2.2 9.1 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA PF00004.24 EPS26791.1 - 0.081 13.1 2.4 1.3 9.1 1.7 2.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 EPS26791.1 - 0.084 12.8 0.0 0.48 10.4 0.0 2.3 3 1 0 3 3 1 0 50S ribosome-binding GTPase Parvo_NS1 PF01057.12 EPS26791.1 - 0.085 11.7 0.0 0.27 10.0 0.0 1.8 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ABC_tran PF00005.22 EPS26791.1 - 0.11 12.7 0.0 0.42 10.9 0.0 1.9 1 0 0 1 1 1 0 ABC transporter Reo_sigmaC PF04582.7 EPS26791.1 - 0.11 11.6 3.6 1.7 7.7 0.0 2.4 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DEK_C PF08766.6 EPS26792.1 - 0.024 14.4 0.0 0.061 13.1 0.0 1.7 1 0 0 1 1 1 0 DEK C terminal domain EntA_Immun PF08951.5 EPS26793.1 - 0.0021 18.1 0.0 0.0031 17.6 0.0 1.2 1 0 0 1 1 1 1 Enterocin A Immunity Adaptin_N PF01602.15 EPS26794.1 - 1e-148 495.9 2.5 1.3e-148 495.5 1.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EPS26794.1 - 2e-31 109.2 0.3 1.6e-27 96.4 0.1 2.9 2 1 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EPS26794.1 - 5.7e-20 71.3 1.1 2.7e-06 27.5 0.0 6.0 4 2 2 6 6 6 4 HEAT repeats HEAT PF02985.17 EPS26794.1 - 6e-11 41.4 3.2 0.016 15.2 0.0 6.3 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 EPS26794.1 - 8.5e-06 26.1 1.5 2 9.0 0.0 6.7 7 1 1 8 8 8 1 HEAT-like repeat Arm PF00514.18 EPS26794.1 - 0.0012 18.5 0.8 8.3 6.4 0.0 5.2 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 EPS26794.1 - 0.0012 18.2 0.2 1.9 7.8 0.0 3.7 3 1 1 4 4 4 2 CLASP N terminal AF0941-like PF14591.1 EPS26794.1 - 0.11 12.5 0.9 0.32 11.0 0.6 1.8 1 0 0 1 1 1 0 AF0941-like S_100 PF01023.14 EPS26794.1 - 0.13 11.5 0.0 1.4 8.3 0.0 2.5 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain ADH_N PF08240.7 EPS26795.1 - 1.1e-22 79.8 3.6 1.9e-22 79.1 2.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPS26795.1 - 4.2e-16 58.6 0.0 7.1e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPS26795.1 - 2.6e-07 31.5 0.0 4.3e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EPS26795.1 - 0.0025 16.9 0.0 0.0038 16.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thr_synth_N PF14821.1 EPS26796.1 - 2.7e-30 104.2 0.0 1.9e-29 101.4 0.0 2.3 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.20 EPS26796.1 - 7.8e-18 64.7 0.0 2.3e-17 63.2 0.0 1.7 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Collagen PF01391.13 EPS26797.1 - 0.00023 20.6 64.0 1.5e+04 -23.9 44.4 3.7 1 1 0 1 1 1 0 Collagen triple helix repeat (20 copies) FAM196 PF15265.1 EPS26798.1 - 0.51 9.5 17.1 0.59 9.3 11.9 1.0 1 0 0 1 1 1 0 FAM196 family DUF605 PF04652.11 EPS26798.1 - 3.1 7.0 19.3 3.6 6.8 13.4 1.1 1 0 0 1 1 1 0 Vta1 like DNA_primase_S PF01896.14 EPS26799.1 - 2.7e-57 192.6 0.0 4.4e-57 191.9 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit MAM33 PF02330.11 EPS26800.1 - 1.8e-33 116.0 3.0 2.7e-33 115.4 2.1 1.3 1 0 0 1 1 1 1 Mitochondrial glycoprotein DUF2962 PF11176.3 EPS26801.1 - 5.8e-51 172.1 3.1 6.6e-51 171.9 2.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) XPG_I PF00867.13 EPS26802.1 - 4.2e-27 94.0 0.1 9.1e-27 92.9 0.1 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EPS26802.1 - 3e-22 78.7 0.0 1.5e-21 76.5 0.0 2.1 2 0 0 2 2 2 1 XPG N-terminal domain XPG_I_2 PF12813.2 EPS26802.1 - 0.00051 19.6 0.0 0.0011 18.5 0.0 1.6 1 0 0 1 1 1 1 XPG domain containing TPR_2 PF07719.12 EPS26802.1 - 0.12 12.3 0.0 0.41 10.6 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Fig1 PF12351.3 EPS26803.1 - 3.9e-59 199.6 4.7 3.9e-59 199.6 3.3 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 EPS26803.1 - 2.1e-09 37.2 8.3 2.9e-09 36.8 5.8 1.2 1 0 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.8 EPS26803.1 - 0.00042 19.3 6.5 0.00042 19.3 4.5 1.8 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) DUF2410 PF10307.4 EPS26804.1 - 1e-79 266.5 0.0 1.4e-79 266.0 0.0 1.2 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) zf-RING_2 PF13639.1 EPS26805.1 - 9.4e-09 34.9 9.1 1.6e-08 34.2 6.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EPS26805.1 - 6.4e-06 26.0 9.3 1e-05 25.4 6.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPS26805.1 - 1.1e-05 24.9 3.2 1.7e-05 24.4 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPS26805.1 - 1.3e-05 24.7 8.5 2.1e-05 24.0 5.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EPS26805.1 - 0.00037 20.5 8.3 0.0014 18.6 5.8 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-MIZ PF02891.15 EPS26805.1 - 0.045 13.2 6.3 0.078 12.4 4.4 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-Apc11 PF12861.2 EPS26805.1 - 0.11 12.3 0.9 0.27 11.0 0.6 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EPS26805.1 - 1.6 8.4 5.7 2.8 7.7 4.0 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Drc1-Sld2 PF11719.3 EPS26806.1 - 2.6e-111 372.7 19.9 3e-111 372.5 13.8 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein S-antigen PF05756.6 EPS26806.1 - 0.83 9.6 3.3 1.6 8.7 0.1 2.7 3 0 0 3 3 3 0 S-antigen protein Beta-lactamase PF00144.19 EPS26807.1 - 3.2e-52 177.5 0.0 4.4e-52 177.1 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 EPS26807.1 - 6.9e-10 38.6 0.0 1.2e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) Suc_Fer-like PF06999.7 EPS26808.1 - 3.1e-47 161.5 0.0 3.5e-47 161.3 0.0 1.0 1 0 0 1 1 1 1 Sucrase/ferredoxin-like rve PF00665.21 EPS26809.1 - 0.12 12.4 0.0 0.17 11.9 0.0 1.2 1 0 0 1 1 1 0 Integrase core domain Fungal_trans PF04082.13 EPS26810.1 - 1.1e-09 37.6 1.5 1.1e-09 37.6 1.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS26810.1 - 8.4e-09 35.1 7.7 1.6e-08 34.2 5.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_43 PF04616.9 EPS26811.1 - 2.8e-35 121.7 2.0 3.5e-35 121.4 1.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 FMO-like PF00743.14 EPS26812.1 - 4.5e-27 94.4 0.0 7.1e-11 40.9 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EPS26812.1 - 7.7e-18 65.2 0.5 1.1e-16 61.4 0.2 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPS26812.1 - 6.1e-06 26.1 0.0 1.8e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EPS26812.1 - 1.5e-05 25.0 0.0 0.11 12.3 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EPS26812.1 - 5.7e-05 22.2 0.1 0.0048 15.8 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EPS26812.1 - 8.2e-05 22.4 0.0 0.0015 18.3 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EPS26812.1 - 0.015 14.3 0.3 0.033 13.2 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 EPS26812.1 - 0.077 11.4 1.1 0.17 10.3 0.4 1.7 2 0 0 2 2 2 0 HI0933-like protein DAO PF01266.19 EPS26812.1 - 0.079 11.8 0.6 3.1 6.5 0.3 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pirin PF02678.11 EPS26813.1 - 2.2e-23 82.1 0.9 7.2e-23 80.5 0.6 1.8 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.6 EPS26813.1 - 1.8e-07 30.5 0.9 5.4e-05 22.6 0.1 3.6 3 2 0 3 3 3 2 Cupin domain Cupin_3 PF05899.7 EPS26813.1 - 0.003 16.8 0.2 4.9 6.5 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF861) Fungal_trans PF04082.13 EPS26814.1 - 8.4e-17 60.8 0.0 1.5e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS26814.1 - 4.8e-09 35.9 13.3 9.4e-09 35.0 9.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_2 PF02230.11 EPS26814.1 - 0.086 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase NAD_binding_10 PF13460.1 EPS26815.1 - 1.7e-12 47.6 0.0 2.2e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding ADH_zinc_N PF00107.21 EPS26815.1 - 0.067 12.7 0.3 0.34 10.4 0.0 2.2 2 1 0 2 2 2 0 Zinc-binding dehydrogenase SCO1-SenC PF02630.9 EPS26816.1 - 1.3e-58 197.4 0.0 1.7e-58 197.0 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 EPS26816.1 - 2.4e-05 23.9 0.1 4.9e-05 22.9 0.1 1.5 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 EPS26816.1 - 0.00048 20.1 0.0 0.0012 18.9 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like Alpha-amylase PF00128.19 EPS26817.1 - 8.1e-97 324.3 4.5 8.1e-97 324.3 3.1 1.8 2 0 0 2 2 2 1 Alpha amylase, catalytic domain MoaE PF02391.12 EPS26817.1 - 1.1e-27 96.1 0.0 2e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 MoaE protein Cyc-maltodext_C PF10438.4 EPS26817.1 - 0.0062 16.5 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 Cyclo-malto-dextrinase C-terminal domain hDGE_amylase PF14701.1 EPS26817.1 - 0.0064 15.4 0.0 0.01 14.7 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme RRM_1 PF00076.17 EPS26818.1 - 5.7e-13 48.2 0.1 1.6e-05 24.4 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.18 EPS26818.1 - 1.4e-11 43.9 0.3 4.7e-11 42.3 0.2 2.0 1 0 0 1 1 1 1 G-patch domain RRM_6 PF14259.1 EPS26818.1 - 1e-09 38.1 0.1 0.00062 19.6 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.13 EPS26818.1 - 4.5e-09 35.2 2.6 8.1e-09 34.4 1.8 1.5 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others G-patch_2 PF12656.2 EPS26818.1 - 0.00028 20.6 1.0 0.00028 20.6 0.7 2.3 2 0 0 2 2 2 1 DExH-box splicing factor binding site Antimicrobial10 PF08105.6 EPS26818.1 - 0.044 13.4 0.3 0.12 12.0 0.2 1.7 1 0 0 1 1 1 0 Metchnikowin family RRM_5 PF13893.1 EPS26818.1 - 0.065 13.0 0.0 0.23 11.3 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2956 PF11169.3 EPS26818.1 - 0.94 9.4 5.9 0.6 10.0 0.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) RED_N PF07808.8 EPS26818.1 - 8.7 5.4 8.0 0.21 10.7 0.4 2.0 2 0 0 2 2 2 0 RED-like protein N-terminal region DUF3433 PF11915.3 EPS26820.1 - 1.4e-30 105.3 15.0 3.6e-24 84.7 2.1 3.3 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) SUR7 PF06687.7 EPS26821.1 - 2e-29 102.6 12.6 2.5e-29 102.3 8.7 1.1 1 0 0 1 1 1 1 SUR7/PalI family SCIMP PF15050.1 EPS26821.1 - 0.14 12.1 0.1 0.14 12.1 0.0 2.8 2 1 1 3 3 3 0 SCIMP protein Ion_trans_2 PF07885.11 EPS26822.1 - 4.5e-27 93.5 26.8 4.4e-17 61.5 4.5 3.3 3 0 0 3 3 3 2 Ion channel Yae1_N PF09811.4 EPS26825.1 - 1.6e-11 43.5 0.2 2.8e-11 42.7 0.1 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal SGL PF08450.7 EPS26826.1 - 8.4e-24 84.2 0.2 2.2e-23 82.9 0.2 1.8 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 EPS26826.1 - 3.4e-05 23.8 0.0 0.00015 21.7 0.0 2.1 1 1 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.15 EPS26826.1 - 0.0003 20.7 0.1 0.006 16.5 0.0 2.4 2 0 0 2 2 2 1 Arylesterase Acatn PF13000.2 EPS26829.1 - 1.2e-148 496.1 22.2 8.8e-76 255.5 5.8 3.1 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 DUF3951 PF13131.1 EPS26829.1 - 8.1 6.3 9.1 0.14 11.9 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) CENP-O PF09496.5 EPS26830.1 - 1.5e-27 95.6 0.0 4e-27 94.2 0.0 1.7 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component Abhydrolase_3 PF07859.8 EPS26832.1 - 2.3e-38 131.9 0.0 2.8e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EPS26832.1 - 1.8e-08 33.8 0.0 7.1e-08 31.9 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EPS26832.1 - 2.3e-06 27.6 3.0 3.9e-06 26.9 2.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPS26832.1 - 1.3e-05 24.9 0.0 2.3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EPS26832.1 - 1.8e-05 24.1 0.0 0.0017 17.6 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family AXE1 PF05448.7 EPS26832.1 - 0.0001 20.8 0.0 0.0014 17.1 0.0 2.0 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) DUF2974 PF11187.3 EPS26832.1 - 0.00092 18.6 0.0 0.0015 17.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Esterase PF00756.15 EPS26832.1 - 0.0046 16.4 0.0 1.5 8.1 0.0 2.2 2 0 0 2 2 2 2 Putative esterase BAAT_C PF08840.6 EPS26832.1 - 0.0091 15.7 0.0 0.017 14.8 0.0 1.4 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Chlorophyllase2 PF12740.2 EPS26832.1 - 0.02 13.7 0.0 0.031 13.1 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Peptidase_S15 PF02129.13 EPS26832.1 - 0.021 14.2 0.0 2.6 7.4 0.0 2.2 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_2 PF02230.11 EPS26832.1 - 0.026 13.9 0.0 0.063 12.7 0.0 1.5 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Chlorophyllase PF07224.6 EPS26832.1 - 0.14 10.9 0.0 0.18 10.5 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase CAP_N PF01213.14 EPS26833.1 - 1.1 8.4 4.6 7.5 5.7 0.8 2.3 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DFP PF04127.10 EPS26834.1 - 4.1e-14 52.6 0.0 1.8e-05 24.4 0.0 3.2 3 0 0 3 3 3 3 DNA / pantothenate metabolism flavoprotein Fringe PF02434.11 EPS26835.1 - 2.1e-09 36.9 0.1 1.3e-07 31.1 0.1 2.9 2 1 0 2 2 2 1 Fringe-like PAN_4 PF14295.1 EPS26835.1 - 0.0018 17.9 2.1 0.0042 16.7 1.4 1.6 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.21 EPS26835.1 - 0.002 17.8 1.1 0.0038 16.9 0.8 1.4 1 0 0 1 1 1 1 PAN domain PAN_3 PF08277.7 EPS26835.1 - 0.62 9.7 2.3 1.2 8.7 1.6 1.4 1 0 0 1 1 1 0 PAN-like domain Polysacc_deac_1 PF01522.16 EPS26836.1 - 2.3e-19 69.2 0.0 4.3e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase ERF PF04404.7 EPS26836.1 - 0.12 11.8 1.0 0.24 10.9 0.7 1.4 1 0 0 1 1 1 0 ERF superfamily DEAD PF00270.24 EPS26837.1 - 3.5e-41 140.4 0.0 6.2e-41 139.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPS26837.1 - 2e-20 72.3 0.1 4.2e-20 71.3 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EPS26837.1 - 0.076 11.4 0.0 7.8 4.7 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1253) CMS1 PF14617.1 EPS26837.1 - 0.19 10.7 0.0 0.34 9.9 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Fumble PF03630.9 EPS26838.1 - 5.1e-135 449.7 1.3 3.6e-134 446.9 0.9 1.9 1 1 0 1 1 1 1 Fumble GPI2 PF06432.6 EPS26839.1 - 6.5e-125 416.1 0.9 7.6e-125 415.9 0.6 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase IncA PF04156.9 EPS26839.1 - 0.62 9.6 2.7 1.2 8.7 1.9 1.4 1 0 0 1 1 1 0 IncA protein Glyco_hydro_18 PF00704.23 EPS26840.1 - 8.7e-52 176.6 3.2 9.4e-51 173.2 2.2 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EPS26840.1 - 2.1e-06 27.6 21.4 4e-06 26.7 14.8 1.5 1 0 0 1 1 1 1 Chitin recognition protein Aldedh PF00171.17 EPS26841.1 - 1.6e-156 521.2 0.1 1.9e-156 521.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FSH1 PF03959.8 EPS26842.1 - 5.3e-40 137.1 0.0 6.2e-40 136.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EPS26842.1 - 3.8e-06 26.7 0.0 4.7e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 EPS26842.1 - 0.0064 16.2 0.0 0.009 15.7 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.2 EPS26842.1 - 0.022 14.6 0.4 0.44 10.3 0.1 2.0 1 1 1 2 2 2 0 Alpha/beta hydrolase family IucA_IucC PF04183.7 EPS26842.1 - 0.067 12.4 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 IucA / IucC family DLH PF01738.13 EPS26842.1 - 0.1 11.8 0.0 1.1 8.4 0.0 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family ADH_zinc_N PF00107.21 EPS26842.1 - 0.13 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase FAD_binding_4 PF01565.18 EPS26844.1 - 4.6e-17 61.7 2.4 8.4e-17 60.9 1.7 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EPS26844.1 - 2.4e-08 33.7 0.1 6.3e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like Nup88 PF10168.4 EPS26845.1 - 0.038 11.8 0.2 0.048 11.4 0.1 1.1 1 0 0 1 1 1 0 Nuclear pore component Amidohydro_2 PF04909.9 EPS26846.1 - 5.5e-19 68.7 0.0 1.9e-18 67.0 0.0 1.9 2 1 0 2 2 2 1 Amidohydrolase Aldedh PF00171.17 EPS26847.1 - 4.5e-161 536.2 0.2 5e-161 536.1 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EPS26847.1 - 3.5e-05 22.7 0.0 6.8e-05 21.7 0.0 1.4 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 EPS26847.1 - 0.00078 18.7 0.0 0.14 11.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) NadA PF02445.11 EPS26847.1 - 0.031 13.0 0.1 0.1 11.4 0.0 1.8 2 0 0 2 2 2 0 Quinolinate synthetase A protein MFS_1 PF07690.11 EPS26850.1 - 7.6e-20 70.9 28.6 7.6e-20 70.9 19.8 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS26850.1 - 0.0006 18.4 32.9 0.0014 17.3 20.5 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter Peptidase_M56 PF05569.6 EPS26850.1 - 0.0034 16.4 0.2 0.076 11.9 0.0 2.2 2 0 0 2 2 2 1 BlaR1 peptidase M56 Axin_b-cat_bind PF08833.5 EPS26851.1 - 1.6 8.4 6.5 4.5 7.0 0.3 3.0 3 0 0 3 3 3 0 Axin beta-catenin binding domain Zn_clus PF00172.13 EPS26852.1 - 1e-06 28.5 9.6 1e-06 28.5 6.7 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EPS26853.1 - 3.2e-35 121.4 27.1 3.2e-35 121.4 18.8 2.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS26853.1 - 2.1e-12 46.3 13.1 2.1e-12 46.3 9.1 3.1 3 1 0 3 3 3 2 Sugar (and other) transporter UPF0016 PF01169.14 EPS26854.1 - 7.3e-42 141.3 24.8 4.7e-21 74.7 5.6 2.4 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Myb_DNA-binding PF00249.26 EPS26855.1 - 2.2e-06 27.5 0.2 6.4e-06 26.1 0.1 1.9 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EPS26855.1 - 5.5e-06 26.3 0.3 1.8e-05 24.7 0.1 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain SLIDE PF09111.5 EPS26855.1 - 0.026 14.2 0.0 0.064 12.9 0.0 1.7 1 0 0 1 1 1 0 SLIDE TRF PF08558.5 EPS26855.1 - 0.064 12.5 0.5 2.9 7.1 0.2 2.8 2 1 0 2 2 2 0 Telomere repeat binding factor (TRF) ATG2_CAD PF13329.1 EPS26855.1 - 0.11 12.0 0.0 0.62 9.6 0.0 2.2 2 0 0 2 2 2 0 Autophagy-related protein 2 CAD motif PBP1_TM PF14812.1 EPS26855.1 - 6.1 7.2 16.7 0.67 10.3 7.1 2.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal WSC PF01822.14 EPS26856.1 - 3.4e-13 49.3 5.6 3.4e-13 49.3 3.8 1.8 2 1 0 2 2 2 1 WSC domain Late_protein_L2 PF00513.13 EPS26856.1 - 0.09 11.6 1.0 0.11 11.2 0.7 1.1 1 0 0 1 1 1 0 Late Protein L2 Peptidase_M20 PF01546.23 EPS26857.1 - 1.9e-26 92.7 0.0 3.5e-26 91.8 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EPS26857.1 - 1.6e-08 34.2 0.0 3.5e-08 33.1 0.0 1.6 1 1 0 1 1 1 1 Peptidase dimerisation domain DUF1793 PF08760.6 EPS26858.1 - 3.1e-70 235.4 0.7 6.7e-70 234.3 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) Annexin PF00191.15 EPS26860.1 - 2.9e-13 49.5 6.0 0.00048 19.9 0.1 4.5 4 0 0 4 4 4 4 Annexin Septin PF00735.13 EPS26861.1 - 6.2e-33 114.0 0.0 1.2e-12 47.4 0.0 3.1 3 0 0 3 3 3 3 Septin MMR_HSR1 PF01926.18 EPS26861.1 - 0.00024 21.0 0.0 0.00063 19.6 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EPS26861.1 - 0.014 15.8 0.0 0.057 13.9 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein Dynamin_N PF00350.18 EPS26861.1 - 0.02 14.7 0.2 0.085 12.6 0.0 2.1 2 1 0 2 2 2 0 Dynamin family FtsK_SpoIIIE PF01580.13 EPS26861.1 - 0.052 13.0 0.0 0.097 12.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.1 EPS26861.1 - 0.058 13.7 0.1 0.13 12.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF946 PF06101.6 EPS26862.1 - 2.8e-11 42.1 1.1 1.1e-09 36.8 0.2 2.2 2 0 0 2 2 2 2 Plant protein of unknown function (DUF946) NPP1 PF05630.6 EPS26862.1 - 0.03 14.0 1.2 0.044 13.5 0.8 1.2 1 0 0 1 1 1 0 Necrosis inducing protein (NPP1) DOPA_dioxygen PF08883.6 EPS26863.1 - 4.1e-32 110.3 0.0 5.3e-32 109.9 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family MIP-T3 PF10243.4 EPS26864.1 - 9.5 4.5 39.7 13 4.0 27.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Prefoldin PF02996.12 EPS26865.1 - 0.0041 16.7 1.9 0.0041 16.7 1.3 3.1 2 2 1 3 3 3 1 Prefoldin subunit Baculo_PEP_C PF04513.7 EPS26865.1 - 0.026 14.3 3.1 0.069 12.9 0.4 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 EPS26865.1 - 0.087 11.9 0.5 0.21 10.7 0.2 1.6 1 1 1 2 2 2 0 Reovirus sigma C capsid protein ISG65-75 PF11727.3 EPS26865.1 - 0.82 8.6 6.9 0.34 9.9 1.5 2.1 2 0 0 2 2 2 0 Invariant surface glycoprotein TBPIP PF07106.8 EPS26865.1 - 1.9 7.9 14.7 0.41 10.1 1.3 2.8 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Filament PF00038.16 EPS26865.1 - 2.6 7.4 19.8 40 3.5 13.8 2.3 1 1 0 1 1 1 0 Intermediate filament protein Mod_r PF07200.8 EPS26865.1 - 6.7 6.6 15.7 0.97 9.3 4.0 2.6 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF4446 PF14584.1 EPS26865.1 - 7.2 6.4 7.3 1.9 8.3 1.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4446) DUF947 PF06102.7 EPS26865.1 - 8 6.2 10.9 13 5.5 2.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF947) FlaC_arch PF05377.6 EPS26865.1 - 9.1 6.2 8.4 8.4 6.3 0.3 3.0 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Ribosomal_S4 PF00163.14 EPS26866.1 - 1.2e-30 105.7 1.0 1.9e-30 105.0 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EPS26866.1 - 6.6e-13 47.8 0.7 6.6e-13 47.8 0.5 2.3 3 0 0 3 3 3 1 S4 domain Ribosomal_L21e PF01157.13 EPS26867.1 - 3.3e-40 135.8 4.1 3.3e-40 135.8 2.8 1.5 2 0 0 2 2 2 1 Ribosomal protein L21e Thioredoxin PF00085.15 EPS26868.1 - 5.2e-28 96.7 0.0 6.2e-28 96.5 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EPS26868.1 - 4.4e-06 26.8 0.1 6.3e-05 23.1 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EPS26868.1 - 1.5e-05 24.9 0.0 2.6e-05 24.2 0.0 1.4 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EPS26868.1 - 2.3e-05 23.9 0.0 2.6e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Redoxin PF08534.5 EPS26868.1 - 0.002 17.6 0.0 0.0039 16.7 0.0 1.5 1 1 1 2 2 2 1 Redoxin AhpC-TSA PF00578.16 EPS26868.1 - 0.0069 16.0 0.0 0.013 15.1 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Phosducin PF02114.11 EPS26868.1 - 0.022 13.5 0.0 0.025 13.3 0.0 1.1 1 0 0 1 1 1 0 Phosducin HrcA_DNA-bdg PF03444.10 EPS26868.1 - 0.072 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding Toxin-deaminase PF14424.1 EPS26868.1 - 0.14 12.1 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases RRM_6 PF14259.1 EPS26869.1 - 3.8e-06 26.7 0.0 6.6e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS26869.1 - 0.00033 20.4 0.1 0.00063 19.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPS26869.1 - 0.0084 15.7 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SecE PF00584.15 EPS26870.1 - 1.5e-12 46.8 0.0 1.8e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex WD40 PF00400.27 EPS26871.1 - 2.8e-20 71.3 15.7 1.3e-05 24.8 0.4 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat PQQ_3 PF13570.1 EPS26871.1 - 0.00018 21.6 0.2 1 9.7 0.0 3.5 3 0 0 3 3 3 2 PQQ-like domain Cytochrom_D1 PF02239.11 EPS26871.1 - 0.0017 16.7 1.7 0.62 8.3 0.0 3.8 4 1 0 4 4 4 2 Cytochrome D1 heme domain PX PF00787.19 EPS26872.1 - 5.6e-27 93.7 0.2 6.8e-27 93.5 0.1 1.1 1 0 0 1 1 1 1 PX domain FAM91_N PF14647.1 EPS26872.1 - 0.1 11.6 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 FAM91 N-terminus Myb_DNA-bind_6 PF13921.1 EPS26873.1 - 4.5e-16 58.6 0.0 8.5e-07 28.9 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EPS26873.1 - 2.3e-13 49.9 0.3 1.5e-06 28.1 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Ribosomal_S4e PF00900.15 EPS26877.1 - 6.5e-34 115.4 0.2 1.3e-33 114.4 0.2 1.5 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 EPS26877.1 - 1.4e-17 63.2 3.8 3e-17 62.1 2.6 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 EPS26877.1 - 1.5e-06 27.4 0.0 3e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 EPS26877.1 - 0.0017 18.0 0.3 0.0017 18.0 0.2 3.5 4 1 0 4 4 4 1 KOW motif Semialdhyde_dhC PF02774.13 EPS26878.1 - 1e-33 116.7 0.0 1.4e-33 116.3 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 EPS26878.1 - 4.6e-29 101.1 0.0 1.2e-28 99.8 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.11 EPS26878.1 - 0.067 13.7 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase FAD-oxidase_C PF02913.14 EPS26879.1 - 3e-61 206.9 0.0 4e-61 206.4 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EPS26879.1 - 4.7e-37 126.5 0.0 1.2e-36 125.2 0.0 1.7 1 0 0 1 1 1 1 FAD binding domain SLA_LP_auto_ag PF05889.8 EPS26879.1 - 0.068 11.6 0.0 0.14 10.5 0.0 1.5 2 0 0 2 2 2 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Cast PF10174.4 EPS26880.1 - 1.2e-06 26.9 49.6 2e-06 26.2 34.4 1.3 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone DUF4618 PF15397.1 EPS26880.1 - 0.0042 16.4 10.9 0.0042 16.4 7.5 3.5 1 1 1 2 2 2 1 Domain of unknown function (DUF4618) Bacillus_HBL PF05791.6 EPS26880.1 - 0.0073 15.6 0.2 0.0073 15.6 0.2 4.5 3 1 2 5 5 5 1 Bacillus haemolytic enterotoxin (HBL) CENP-F_leu_zip PF10473.4 EPS26880.1 - 0.1 12.4 59.5 3.1 7.6 13.8 4.5 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 EPS26880.1 - 0.47 9.6 53.3 0.6 9.2 7.6 3.5 1 1 2 3 3 3 0 Growth-arrest specific micro-tubule binding ADIP PF11559.3 EPS26880.1 - 3.4 7.5 52.2 1.6 8.5 4.0 3.9 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding EB1 PF03271.12 EPS26880.1 - 4.4 7.4 6.2 6.6 6.8 0.0 4.0 3 1 0 3 3 3 0 EB1-like C-terminal motif RdRP PF05183.7 EPS26881.1 - 4e-183 610.2 0.0 5.5e-183 609.8 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase DNA_pol_B PF00136.16 EPS26882.1 - 4e-93 312.7 0.0 6.1e-93 312.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EPS26882.1 - 4e-21 75.2 0.4 1.2e-10 40.7 0.1 2.5 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EPS26882.1 - 5e-20 71.2 4.4 5e-20 71.2 3.1 2.1 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta Slu7 PF11708.3 EPS26883.1 - 4.7e-81 272.0 17.3 4.7e-81 272.0 12.0 1.6 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 EPS26883.1 - 0.016 14.8 0.7 0.041 13.5 0.5 1.7 1 0 0 1 1 1 0 Zinc knuckle Ribosomal_L37e PF01907.14 EPS26884.1 - 8.4e-28 95.9 12.4 1.3e-27 95.3 8.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 EPS26884.1 - 0.0012 18.6 3.0 0.0019 17.9 2.1 1.2 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 EPS26884.1 - 0.04 13.1 2.3 0.61 9.3 0.2 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EPS26884.1 - 0.048 13.1 2.6 2.9 7.4 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain C1_1 PF00130.17 EPS26884.1 - 0.066 12.9 2.3 0.11 12.2 1.6 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc_ribbon_6 PF14599.1 EPS26884.1 - 0.38 10.5 2.3 0.53 10.1 1.6 1.2 1 0 0 1 1 1 0 Zinc-ribbon zf-C3HC4_2 PF13923.1 EPS26884.1 - 1.3 9.1 5.0 2 8.4 3.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-CCHC_5 PF14787.1 EPS26884.1 - 1.7 8.2 7.2 1.1 8.8 3.8 1.7 1 1 0 1 1 1 0 GAG-polyprotein viral zinc-finger DUF2348 PF09807.4 EPS26885.1 - 2.5e-12 46.4 0.0 5.2e-05 22.4 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2348) KaiC PF06745.8 EPS26885.1 - 0.17 10.9 0.0 0.3 10.1 0.0 1.3 1 0 0 1 1 1 0 KaiC Fungal_trans PF04082.13 EPS26886.1 - 2.8e-34 118.1 0.4 4.4e-34 117.5 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS26886.1 - 2.9e-10 39.8 10.5 5.5e-10 39.0 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 EPS26886.1 - 2e-05 24.4 0.1 4.2e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 Gal4-like dimerisation domain CIA30 PF08547.7 EPS26887.1 - 1.1e-41 142.3 0.1 1.4e-41 141.9 0.1 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) CBM_11 PF03425.8 EPS26887.1 - 0.038 13.6 0.1 0.059 13.0 0.1 1.3 1 1 0 1 1 1 0 Carbohydrate binding domain (family 11) TP_methylase PF00590.15 EPS26888.1 - 5.5e-48 163.4 0.2 9e-48 162.7 0.1 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 EPS26888.1 - 1.6e-14 54.0 0.0 2.8e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EPS26888.1 - 2.7e-12 45.8 0.1 1.4e-08 33.9 0.0 2.4 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal CysG_dimeriser PF10414.4 EPS26888.1 - 0.12 11.9 0.6 0.56 9.7 0.4 2.1 1 1 0 1 1 1 0 Sirohaem synthase dimerisation region PCI PF01399.22 EPS26889.1 - 1.2e-19 70.5 0.6 3.7e-19 68.9 0.0 2.1 2 0 0 2 2 2 1 PCI domain Asp_Glu_race_2 PF14669.1 EPS26889.1 - 0.0041 16.4 1.0 0.3 10.3 0.1 2.4 2 0 0 2 2 2 2 Putative aspartate racemase PCI_Csn8 PF10075.4 EPS26889.1 - 0.026 14.2 0.1 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 EST1_DNA_bind PF10373.4 EPS26889.1 - 0.035 13.3 0.1 0.75 8.9 0.0 2.3 2 0 0 2 2 2 0 Est1 DNA/RNA binding domain DUF3702 PF12486.3 EPS26889.1 - 2.8 7.5 7.6 0.81 9.3 0.5 3.2 3 1 1 4 4 4 0 ImpA domain protein FSH1 PF03959.8 EPS26890.1 - 2.9e-67 226.2 0.0 3.4e-67 225.9 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EPS26890.1 - 1.4e-05 24.8 0.0 1.8e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPS26890.1 - 0.00028 20.8 2.2 0.0047 16.8 1.5 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EPS26890.1 - 0.14 11.5 0.0 3.4 7.0 0.1 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Patched PF02460.13 EPS26891.1 - 0.0046 14.9 0.0 0.0051 14.7 0.0 1.0 1 0 0 1 1 1 1 Patched family Ribosomal_S27e PF01667.12 EPS26892.1 - 5.8e-29 99.4 6.6 7.4e-29 99.0 4.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 EPS26892.1 - 0.0039 17.0 1.1 0.0045 16.8 0.8 1.2 1 0 0 1 1 1 1 IBR domain zf-CSL PF05207.8 EPS26892.1 - 0.1 12.1 0.8 0.19 11.2 0.5 1.5 1 0 0 1 1 1 0 CSL zinc finger CDP-OH_P_transf PF01066.16 EPS26894.1 - 1.9e-16 60.2 5.4 7.4e-16 58.3 3.7 2.1 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Prenyltrans PF00432.16 EPS26894.1 - 0.068 12.7 0.0 0.19 11.3 0.0 1.8 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat NIPSNAP PF07978.8 EPS26896.1 - 2.5e-40 136.5 0.7 1.9e-28 98.4 0.1 2.4 2 0 0 2 2 2 2 NIPSNAP Pyridox_oxidase PF01243.15 EPS26897.1 - 4.5e-13 49.0 0.1 1.6e-12 47.2 0.0 1.9 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Colicin_C PF12106.3 EPS26897.1 - 0.27 10.8 5.2 0.17 11.5 0.6 2.5 2 0 0 2 2 2 0 Colicin C terminal ribonuclease domain BPL_LplA_LipB PF03099.14 EPS26898.1 - 1.6e-09 37.8 0.0 2.9e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Ras PF00071.17 EPS26899.1 - 2e-50 170.3 0.0 2.4e-50 170.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPS26899.1 - 4.1e-14 53.0 0.0 5.6e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPS26899.1 - 1.2e-08 34.4 0.0 1.5e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EPS26899.1 - 0.00078 18.6 0.0 0.00096 18.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EPS26899.1 - 0.02 14.1 0.0 0.03 13.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PCI PF01399.22 EPS26900.1 - 4.1e-19 68.8 0.4 1.2e-18 67.3 0.0 2.0 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EPS26900.1 - 1.1e-06 28.4 0.0 2.3e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_2 PF07719.12 EPS26900.1 - 0.0025 17.6 1.3 0.17 11.8 0.0 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat DUF1480 PF07351.8 EPS26900.1 - 0.0028 17.6 0.0 0.01 15.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1480) TPR_7 PF13176.1 EPS26900.1 - 0.0054 16.4 0.5 0.54 10.1 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 EPS26900.1 - 0.018 14.9 0.1 0.95 9.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EPS26900.1 - 0.019 14.5 0.8 0.37 10.4 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.12 EPS26900.1 - 0.024 13.7 0.1 4.1 6.4 0.0 2.2 2 0 0 2 2 2 0 Protein tyrosine kinase KilA-N PF04383.8 EPS26900.1 - 0.034 13.7 0.2 0.15 11.7 0.1 2.1 2 1 0 2 2 2 0 KilA-N domain Ipi1_N PF12333.3 EPS26900.1 - 0.041 13.8 0.1 0.45 10.4 0.0 2.4 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation TPR_12 PF13424.1 EPS26900.1 - 0.079 12.9 1.5 0.7 9.8 0.2 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EPS26900.1 - 0.095 13.2 0.3 8.4 7.1 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EPS26900.1 - 0.31 10.9 3.1 0.66 9.8 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat PS_pyruv_trans PF04230.8 EPS26901.1 - 0.1 12.2 0.0 0.11 12.1 0.0 1.0 1 0 0 1 1 1 0 Polysaccharide pyruvyl transferase Peptidase_C65 PF10275.4 EPS26904.1 - 6.9e-65 218.7 0.0 9.1e-65 218.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain DeoC PF01791.4 EPS26908.1 - 4e-46 157.2 1.4 5e-46 156.9 1.0 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase DHO_dh PF01180.16 EPS26908.1 - 0.00098 18.1 0.2 0.0019 17.1 0.1 1.4 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 EPS26908.1 - 0.019 13.8 0.2 0.037 12.8 0.2 1.5 1 1 0 1 1 1 0 FMN-dependent dehydrogenase DUF2763 PF10961.3 EPS26909.1 - 0.00029 21.1 4.5 0.00066 20.0 3.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2763) Sugar_tr PF00083.19 EPS26910.1 - 4.6e-120 401.2 19.1 8.1e-120 400.4 13.2 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS26910.1 - 1e-24 86.9 62.9 2.6e-19 69.1 23.9 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4066 PF13278.1 EPS26911.1 - 7e-14 51.4 0.0 9.1e-14 51.0 0.0 1.3 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EPS26911.1 - 3e-09 36.5 0.0 4.2e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 EPS26911.1 - 0.073 12.5 0.0 0.092 12.1 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Asp PF00026.18 EPS26912.1 - 1.2e-55 189.0 1.0 2.2e-55 188.1 0.7 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EPS26912.1 - 2.4e-06 27.2 0.0 2.2e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 EPS26912.1 - 3.8e-06 26.9 0.1 9e-05 22.4 0.0 3.0 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EPS26912.1 - 0.0013 19.1 3.0 0.49 10.9 0.6 3.6 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 EPS26912.1 - 0.023 14.5 0.0 3.1 7.6 0.0 2.7 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Sugar_tr PF00083.19 EPS26913.1 - 1.8e-77 260.8 23.5 2.1e-77 260.6 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS26913.1 - 5.7e-11 41.7 41.1 1.9e-07 30.1 13.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3767 PF12597.3 EPS26913.1 - 1.6 8.3 3.7 11 5.6 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3767) Abhydrolase_3 PF07859.8 EPS26914.1 - 1.1e-17 64.3 0.1 1.6e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPS26914.1 - 3.7e-09 36.4 0.0 7.5e-09 35.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EPS26914.1 - 8.2e-07 28.1 0.0 2.4e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.16 EPS26914.1 - 9.2e-07 28.2 0.0 0.00092 18.4 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EPS26914.1 - 5e-06 26.5 2.4 7.5e-06 25.9 1.6 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EPS26914.1 - 0.00013 20.5 0.0 0.085 11.3 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.4 EPS26914.1 - 0.00022 20.5 1.5 0.021 14.0 0.4 2.8 2 1 0 2 2 2 1 Esterase PHB depolymerase Chlorophyllase2 PF12740.2 EPS26914.1 - 0.0003 19.7 0.0 0.0004 19.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Esterase PF00756.15 EPS26914.1 - 0.00087 18.7 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.15 EPS26914.1 - 0.0011 18.6 0.0 0.031 13.8 0.0 2.3 3 0 0 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EPS26914.1 - 0.0013 18.1 0.0 0.025 14.0 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Chlorophyllase PF07224.6 EPS26914.1 - 0.02 13.7 0.0 0.027 13.2 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase UPF0546 PF10639.4 EPS26915.1 - 1.2e-36 124.9 0.6 2.5e-29 101.3 0.2 2.1 2 0 0 2 2 2 2 Uncharacterised protein family UPF0546 EamA PF00892.15 EPS26915.1 - 0.93 9.5 7.2 0.47 10.4 2.8 2.0 2 0 0 2 2 2 0 EamA-like transporter family Chitin_synth_1 PF01644.12 EPS26916.1 - 2.2e-81 271.4 0.0 3.2e-81 270.8 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EPS26916.1 - 2.2e-30 104.1 0.0 4.1e-30 103.3 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EPS26916.1 - 4.6e-22 78.1 2.1 1.6e-18 66.4 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EPS26916.1 - 6.9e-09 35.6 3.9 6.9e-09 35.6 2.7 3.0 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EPS26916.1 - 1.4e-07 31.5 0.0 7.1e-07 29.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_hydro_3_C PF01915.17 EPS26916.1 - 0.7 9.3 3.7 10 5.5 0.9 2.4 2 0 0 2 2 2 0 Glycosyl hydrolase family 3 C-terminal domain LMWPc PF01451.16 EPS26918.1 - 5.4e-32 110.9 0.0 5.1e-31 107.8 0.0 1.9 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase COQ7 PF03232.8 EPS26919.1 - 7.2e-62 207.8 0.7 8.8e-62 207.5 0.5 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 EPS26919.1 - 1.2e-06 28.9 1.9 5.2e-06 26.8 1.3 1.9 1 1 0 1 1 1 1 Rubrerythrin Plus-3 PF03126.13 EPS26920.1 - 2.4e-33 114.4 0.0 8.4e-33 112.6 0.0 1.9 2 0 0 2 2 2 1 Plus-3 domain DUF4463 PF14703.1 EPS26920.1 - 1.9 9.0 8.9 0.76 10.3 0.6 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4463) MRC1 PF09444.5 EPS26921.1 - 1.7e-39 135.4 20.1 1.7e-39 135.4 14.0 6.8 6 1 1 7 7 7 2 MRC1-like domain Hydrolase_like PF13242.1 EPS26922.1 - 2.7e-07 30.2 0.0 5e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 EPS26922.1 - 0.00016 21.9 0.0 0.25 11.5 0.0 3.3 2 2 0 2 2 2 2 Haloacid dehalogenase-like hydrolase FAD_binding_3 PF01494.14 EPS26924.1 - 2.3e-18 66.3 0.1 2.3e-10 40.0 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EPS26924.1 - 1.1e-07 31.7 0.5 2.9e-07 30.4 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EPS26924.1 - 0.0002 20.4 2.0 0.00048 19.1 0.8 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPS26924.1 - 0.00038 19.4 2.0 0.001 18.0 1.0 1.8 1 1 1 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EPS26924.1 - 0.0026 17.6 0.9 0.0052 16.6 0.6 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 EPS26924.1 - 0.0087 15.4 1.3 0.017 14.5 0.2 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.12 EPS26924.1 - 0.012 14.6 0.1 0.021 13.9 0.1 1.4 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.17 EPS26924.1 - 0.054 12.3 0.7 0.087 11.6 0.5 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EPS26924.1 - 0.06 13.1 0.9 0.14 11.9 0.2 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 EPS26924.1 - 0.095 13.1 0.2 0.21 12.0 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EPS26924.1 - 0.15 10.6 0.5 0.24 9.9 0.4 1.3 1 0 0 1 1 1 0 Tryptophan halogenase TBCC PF07986.7 EPS26925.1 - 1.4e-34 118.0 1.2 2.1e-34 117.4 0.9 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C Pro-kuma_activ PF09286.6 EPS26926.1 - 6e-35 120.3 0.0 1.1e-34 119.5 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EPS26926.1 - 0.0016 17.6 0.0 0.004 16.3 0.0 1.5 1 1 0 1 1 1 1 Subtilase family SAC3_GANP PF03399.11 EPS26927.1 - 4.9e-24 85.0 0.0 6.6e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EPS26927.1 - 1.5e-20 73.3 0.0 2.5e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 DUF3433 PF11915.3 EPS26927.1 - 0.033 14.3 0.0 0.067 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3433) WD40 PF00400.27 EPS26928.1 - 0.031 14.1 7.1 1.2 9.1 0.0 4.8 5 1 0 5 5 5 0 WD domain, G-beta repeat DUF1917 PF08939.5 EPS26929.1 - 2e-77 260.2 0.0 2.3e-77 260.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) TrmB PF01978.14 EPS26929.1 - 0.038 13.6 0.8 0.076 12.7 0.0 1.8 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB Vps51 PF08700.6 EPS26930.1 - 5.9e-27 93.3 0.0 9.5e-27 92.6 0.0 1.3 1 0 0 1 1 1 1 Vps51/Vps67 COG5 PF10392.4 EPS26930.1 - 0.026 14.4 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Dor1 PF04124.7 EPS26930.1 - 0.057 11.8 0.0 0.068 11.6 0.0 1.2 1 0 0 1 1 1 0 Dor1-like family Sec5 PF15469.1 EPS26930.1 - 0.066 12.9 0.0 0.21 11.2 0.0 1.7 1 1 0 1 1 1 0 Exocyst complex component Sec5 DUF1767 PF08585.7 EPS26931.1 - 3.2e-15 56.1 0.1 5e-15 55.5 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) TPR_11 PF13414.1 EPS26932.1 - 1e-41 140.4 48.4 3.1e-07 29.9 0.2 14.8 13 2 2 15 15 15 11 TPR repeat TPR_16 PF13432.1 EPS26932.1 - 2.6e-22 78.9 53.4 0.00017 22.1 0.0 12.6 13 0 0 13 13 12 6 Tetratricopeptide repeat TPR_2 PF07719.12 EPS26932.1 - 1.4e-21 74.5 53.8 0.0088 15.8 0.0 16.3 18 0 0 18 18 18 7 Tetratricopeptide repeat TPR_17 PF13431.1 EPS26932.1 - 2.8e-21 73.8 25.1 0.23 11.7 0.0 16.1 17 0 0 17 17 17 5 Tetratricopeptide repeat TPR_14 PF13428.1 EPS26932.1 - 1.2e-20 72.1 52.7 0.00095 19.5 0.0 17.0 15 6 4 19 19 18 6 Tetratricopeptide repeat TPR_1 PF00515.23 EPS26932.1 - 6.5e-20 69.8 39.6 0.0011 18.4 0.0 14.8 17 0 0 17 17 17 6 Tetratricopeptide repeat TPR_12 PF13424.1 EPS26932.1 - 8e-16 57.7 48.7 1.1e-07 31.6 0.3 10.4 7 2 5 13 13 13 7 Tetratricopeptide repeat TPR_8 PF13181.1 EPS26932.1 - 1.5e-14 52.6 22.2 0.16 11.8 0.0 12.3 12 2 1 13 13 13 5 Tetratricopeptide repeat TPR_19 PF14559.1 EPS26932.1 - 6.7e-14 51.9 39.1 0.018 15.3 0.3 11.3 12 3 2 14 14 14 6 Tetratricopeptide repeat TPR_6 PF13174.1 EPS26932.1 - 2.3e-08 33.9 32.4 0.003 17.9 0.0 12.4 13 0 0 13 13 13 2 Tetratricopeptide repeat TPR_7 PF13176.1 EPS26932.1 - 4e-06 26.2 19.2 0.043 13.6 0.0 10.3 11 1 0 11 11 11 2 Tetratricopeptide repeat TPR_9 PF13371.1 EPS26932.1 - 0.0014 18.4 11.8 7.1 6.5 0.0 7.1 6 1 0 6 6 6 2 Tetratricopeptide repeat Cellulase PF00150.13 EPS26933.1 - 1.9e-08 33.8 5.1 7.8e-07 28.5 2.0 2.8 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Xpo1 PF08389.7 EPS26934.1 - 1.5e-07 31.3 9.0 3.3e-06 27.0 1.2 4.4 4 1 0 4 4 4 1 Exportin 1-like protein HEAT_2 PF13646.1 EPS26934.1 - 0.0034 17.6 4.8 0.0055 16.9 0.0 3.6 4 0 0 4 4 4 1 HEAT repeats DUF2435 PF10363.4 EPS26934.1 - 0.051 13.4 0.4 35 4.3 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2435) GRIM-19 PF06212.7 EPS26935.1 - 6.8e-24 84.0 0.6 1.3e-23 83.1 0.4 1.4 1 1 0 1 1 1 1 GRIM-19 protein tRNA_m1G_MT PF01746.16 EPS26936.1 - 8.2e-33 113.5 0.0 6e-32 110.7 0.0 2.1 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase VID27 PF08553.5 EPS26937.1 - 0 1175.7 1.8 0 1175.6 1.2 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein Nop14 PF04147.7 EPS26937.1 - 0.26 9.1 18.2 0.56 8.0 12.6 1.4 1 0 0 1 1 1 0 Nop14-like family ECIST_Cterm PF14784.1 EPS26937.1 - 0.35 10.8 4.3 0.95 9.4 3.0 1.7 1 0 0 1 1 1 0 C-terminal domain of the ECSIT protein CDC45 PF02724.9 EPS26937.1 - 8.7 4.2 17.2 16 3.3 11.9 1.3 1 0 0 1 1 1 0 CDC45-like protein zf-Di19 PF05605.7 EPS26938.1 - 0.075 13.1 12.1 0.28 11.3 0.2 5.2 5 0 0 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding DUF3734 PF12536.3 EPS26941.1 - 0.14 12.2 2.3 0.83 9.8 0.4 2.5 2 1 1 3 3 3 0 Patatin phospholipase DNA_primase_lrg PF04104.9 EPS26941.1 - 0.42 9.8 2.0 0.59 9.3 1.1 1.4 1 1 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit RTA1 PF04479.8 EPS26943.1 - 1e-44 152.6 11.8 1e-44 152.6 8.2 1.4 2 0 0 2 2 2 1 RTA1 like protein MgtE PF01769.11 EPS26944.1 - 5.5 7.2 9.5 0.85 9.9 0.6 3.0 1 1 1 3 3 3 0 Divalent cation transporter HNH_2 PF13391.1 EPS26945.1 - 0.0054 16.4 0.0 0.0094 15.7 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease TLD PF07534.11 EPS26947.1 - 2.1e-25 89.3 0.0 4.6e-16 59.0 0.0 2.2 2 0 0 2 2 2 2 TLD Corona_NS2 PF04753.7 EPS26947.1 - 0.024 14.5 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 Coronavirus non-structural protein NS2 Spherulin4 PF12138.3 EPS26948.1 - 1.7e-34 119.4 0.0 2.7e-34 118.7 0.0 1.3 1 0 0 1 1 1 1 Spherulation-specific family 4 MU117 PF15474.1 EPS26948.1 - 3.2e-15 56.3 10.0 9.3e-15 54.8 6.9 1.9 1 0 0 1 1 1 1 Meiotically up-regulated gene family Lipase_GDSL_2 PF13472.1 EPS26948.1 - 6.2e-08 32.9 0.2 1.8e-07 31.5 0.2 1.8 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family fn3 PF00041.16 EPS26948.1 - 0.00015 21.7 0.0 0.00038 20.5 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain F-box-like PF12937.2 EPS26950.1 - 0.00039 20.0 0.2 0.00074 19.1 0.1 1.5 1 0 0 1 1 1 1 F-box-like FNIP PF05725.7 EPS26950.1 - 0.031 14.2 1.1 8.3 6.4 0.0 3.5 4 0 0 4 4 4 0 FNIP Repeat F-box PF00646.28 EPS26950.1 - 0.096 12.3 2.9 0.12 12.0 0.2 2.5 3 0 0 3 3 3 0 F-box domain LRR_4 PF12799.2 EPS26950.1 - 0.11 12.1 1.5 7.9 6.2 0.0 3.6 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) JAB PF01398.16 EPS26952.1 - 1.6e-13 50.3 0.0 4.4e-13 48.9 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease USP8_dimer PF08969.6 EPS26952.1 - 1.3e-09 37.9 1.1 2.5e-09 37.0 0.8 1.4 1 0 0 1 1 1 1 USP8 dimerisation domain Prok-JAB PF14464.1 EPS26952.1 - 8e-06 25.3 0.1 2.6e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain Pkinase PF00069.20 EPS26954.1 - 2e-14 53.3 0.0 2.7e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS26954.1 - 0.00064 18.8 0.0 0.001 18.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPS26954.1 - 0.0032 17.2 0.0 0.0056 16.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EPS26954.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Polyketide_cyc2 PF10604.4 EPS26955.1 - 3.8e-06 27.1 8.1 1.2e-05 25.5 5.6 1.9 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 EPS26955.1 - 0.00011 22.2 0.4 0.00041 20.3 0.3 2.0 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport CRISPR_assoc PF08798.6 EPS26955.1 - 0.00087 19.1 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 CRISPR associated protein Glyco_hydro_28 PF00295.12 EPS26956.1 - 5.1e-39 134.1 11.9 1.1e-37 129.7 5.4 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EPS26956.1 - 0.014 15.1 8.1 0.014 15.1 5.6 2.7 1 1 1 2 2 2 0 Right handed beta helix region Amidase PF01425.16 EPS26957.1 - 2.2e-93 313.4 0.0 2.7e-93 313.2 0.0 1.1 1 0 0 1 1 1 1 Amidase Iso_dh PF00180.15 EPS26959.1 - 3.3e-71 240.0 0.0 3.9e-71 239.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF2543 PF10820.3 EPS26959.1 - 0.13 12.3 0.2 0.27 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2543) FTHFS PF01268.14 EPS26961.1 - 8.5e-256 849.2 0.0 1.3e-255 848.7 0.0 1.3 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EPS26961.1 - 2.6e-67 224.9 1.3 5.5e-67 223.8 0.9 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EPS26961.1 - 2.2e-36 124.4 0.3 5e-36 123.2 0.2 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain WD40 PF00400.27 EPS26962.1 - 7.6e-35 117.5 0.9 2e-10 40.1 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EPS26962.1 - 8.8e-05 20.8 0.1 0.00012 20.4 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Gmad1 PF10647.4 EPS26962.1 - 0.00017 21.1 0.3 0.00041 19.8 0.2 1.5 1 1 1 2 2 2 1 Lipoprotein LpqB beta-propeller domain PQQ_2 PF13360.1 EPS26962.1 - 0.0013 18.2 1.0 0.0023 17.4 0.7 1.5 1 1 0 1 1 1 1 PQQ-like domain MBF1 PF08523.5 EPS26963.1 - 1.3e-25 89.2 0.8 1.3e-25 89.2 0.6 1.6 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 EPS26963.1 - 2.2e-10 40.2 0.1 3.8e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 EPS26963.1 - 2e-05 24.6 0.0 3.8e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 EPS26963.1 - 0.00023 21.1 0.1 0.00041 20.3 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain Glyoxalase_2 PF12681.2 EPS26964.1 - 7.1e-11 42.6 0.0 8.7e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EPS26964.1 - 0.0013 18.7 0.0 0.0037 17.2 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SH3_9 PF14604.1 EPS26965.1 - 2.4e-15 55.8 0.0 4.3e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EPS26965.1 - 1.3e-14 53.2 0.1 2e-14 52.6 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EPS26965.1 - 9.5e-10 37.8 0.0 1.5e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Ank_2 PF12796.2 EPS26966.1 - 6e-39 132.2 0.4 1.6e-19 70.0 0.1 3.6 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EPS26966.1 - 4.7e-30 101.8 3.2 5.2e-06 25.9 0.0 7.5 7 0 0 7 7 7 5 Ankyrin repeat Ank_4 PF13637.1 EPS26966.1 - 2.7e-26 91.4 7.8 2.1e-08 34.4 0.0 6.1 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPS26966.1 - 9e-24 81.1 0.0 0.0014 18.6 0.0 7.5 7 0 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 EPS26966.1 - 5.1e-21 74.2 5.0 4.3e-08 33.1 0.1 5.1 1 1 5 6 6 6 5 Ankyrin repeats (many copies) AIM24 PF01987.12 EPS26967.1 - 7.2e-54 182.5 0.0 8.8e-54 182.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Phostensin_N PF13916.1 EPS26967.1 - 0.17 11.8 2.5 0.42 10.6 1.7 1.6 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal APC_CDC26 PF10471.4 EPS26967.1 - 4.2 8.1 9.5 7.8 7.3 6.6 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 eIF-5_eIF-2B PF01873.12 EPS26968.1 - 3.2e-43 146.3 0.2 6.3e-43 145.4 0.1 1.4 1 0 0 1 1 1 1 Domain found in IF2B/IF5 zinc_ribbon_6 PF14599.1 EPS26968.1 - 0.13 12.0 0.3 16 5.4 0.1 2.5 2 0 0 2 2 2 0 Zinc-ribbon Ykof PF07615.6 EPS26968.1 - 0.14 12.3 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 YKOF-related Family Arc_trans_TRASH PF08394.5 EPS26968.1 - 1.8 8.7 6.7 1.8 8.7 0.2 2.7 1 1 1 2 2 2 0 Archaeal TRASH domain RRM_1 PF00076.17 EPS26971.1 - 3.1e-22 77.9 0.0 4e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS26971.1 - 1.2e-15 57.2 0.0 1.5e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS26971.1 - 7.2e-11 41.7 0.0 9.9e-11 41.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ChaC PF04752.7 EPS26972.1 - 1.3e-53 181.6 0.0 1.6e-53 181.3 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein MFS_1 PF07690.11 EPS26973.1 - 1.6e-49 168.5 65.3 9.4e-49 165.9 44.4 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPS26973.1 - 3.4e-23 81.6 19.5 3.4e-23 81.6 13.5 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EPS26973.1 - 1.9e-15 56.3 13.3 1.9e-15 56.3 9.2 3.5 1 1 1 3 3 3 2 Sugar (and other) transporter EF-hand_1 PF00036.27 EPS26974.1 - 3.4e-22 76.0 6.3 3.6e-08 32.1 0.2 4.7 4 1 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EPS26974.1 - 6.9e-20 69.0 4.0 1.1e-05 24.8 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 EPS26974.1 - 1e-19 70.4 3.0 4.7e-09 36.2 1.4 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EPS26974.1 - 3.6e-19 68.1 5.1 1.3e-09 37.4 0.0 3.8 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 EPS26974.1 - 3.5e-12 45.0 8.3 0.00022 20.4 0.4 4.0 4 1 0 4 4 4 3 EF hand DUF4121 PF13497.1 EPS26974.1 - 0.09 11.7 0.1 6.1 5.7 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4121) adh_short PF00106.20 EPS26975.1 - 2.9e-15 56.5 0.0 4.6e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPS26975.1 - 2.3e-08 33.9 0.0 3.3e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EPS26975.1 - 0.0002 21.2 0.0 0.13 12.0 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase OPT PF03169.10 EPS26976.1 - 2.2e-127 426.1 39.0 2.5e-127 425.9 27.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein GrpE PF01025.14 EPS26976.1 - 0.16 11.4 0.0 0.39 10.2 0.0 1.5 2 0 0 2 2 2 0 GrpE Aminotran_1_2 PF00155.16 EPS26977.1 - 1.5e-42 145.9 0.0 1.8e-42 145.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II GFA PF04828.9 EPS26978.1 - 5.5e-24 83.9 0.1 8.8e-24 83.2 0.1 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 EPS26978.1 - 0.76 9.5 0.1 0.76 9.5 0.0 2.7 3 0 0 3 3 3 0 Nudix N-terminal SRF-TF PF00319.13 EPS26979.1 - 4.6e-23 80.2 0.1 6.9e-23 79.6 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) DUF1708 PF08101.6 EPS26981.1 - 9.3e-154 512.2 0.0 1.2e-153 511.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) DJ-1_PfpI PF01965.19 EPS26982.1 - 6e-23 80.9 0.1 9.1e-23 80.3 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EPS26982.1 - 1.2e-13 50.3 0.0 2.3e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family MFS_2 PF13347.1 EPS26983.1 - 2e-13 49.5 12.0 2e-13 49.5 8.3 2.0 2 0 0 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.2 EPS26983.1 - 0.028 14.1 6.4 0.05 13.3 0.0 3.5 4 0 0 4 4 4 0 MFS_1 like family G6PD_C PF02781.11 EPS26984.1 - 2e-137 456.9 0.0 3.6e-137 456.0 0.0 1.4 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EPS26984.1 - 3.8e-66 222.8 0.1 6.1e-66 222.1 0.1 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF3226 PF11536.3 EPS26984.1 - 0.079 12.4 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3226) Ribosomal_L35Ae PF01247.13 EPS26985.1 - 1.5e-43 146.5 0.4 1.6e-43 146.3 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EPS26985.1 - 0.0014 18.5 0.0 0.8 9.6 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain DUF2406 PF10295.4 EPS26987.1 - 2.6e-22 79.0 1.3 9.1e-22 77.3 0.0 2.6 2 0 0 2 2 2 1 Uncharacterised protein (DUF2406) DUF3602 PF12223.3 EPS26988.1 - 1.6e-18 66.8 10.5 7.7e-14 51.8 2.8 3.0 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Mito_carr PF00153.22 EPS26989.1 - 1.4e-47 159.3 8.3 5.8e-18 64.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CBS PF00571.23 EPS26990.1 - 6.3e-06 25.8 0.1 0.092 12.5 0.0 3.1 2 1 0 2 2 2 2 CBS domain VMA21 PF09446.5 EPS26991.1 - 4.7e-19 68.0 7.7 6.4e-19 67.6 5.4 1.2 1 0 0 1 1 1 1 VMA21-like domain SNF2_N PF00176.18 EPS26992.1 - 2.6e-59 200.4 0.1 3.9e-59 199.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPS26992.1 - 7.8e-14 51.3 0.1 2.1e-13 49.8 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPS26992.1 - 2.9e-09 37.0 0.0 9.5e-09 35.3 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EPS26992.1 - 2e-06 27.3 0.0 4e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 EPS26992.1 - 0.0064 15.3 1.1 1.4 7.6 0.1 2.5 2 1 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 UBA PF00627.26 EPS26992.1 - 0.037 13.8 0.1 0.093 12.6 0.0 1.7 1 0 0 1 1 1 0 UBA/TS-N domain TRAPPC-Trs85 PF12739.2 EPS26992.1 - 0.038 12.6 0.2 0.066 11.8 0.1 1.4 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Dus PF01207.12 EPS26993.1 - 3.6e-42 144.2 0.0 8.7e-42 143.0 0.0 1.6 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Pyrophosphatase PF00719.14 EPS26994.1 - 6.2e-53 178.4 0.2 7.7e-53 178.1 0.2 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Sec20 PF03908.8 EPS26996.1 - 6e-15 54.7 1.0 1.5e-14 53.4 0.7 1.7 1 0 0 1 1 1 1 Sec20 Amidase_3 PF01520.13 EPS26996.1 - 0.065 13.0 1.3 0.39 10.4 0.1 2.2 1 1 1 2 2 2 0 N-acetylmuramoyl-L-alanine amidase MutS_II PF05188.12 EPS26996.1 - 0.3 11.1 4.1 0.75 9.8 2.8 1.6 1 0 0 1 1 1 0 MutS domain II AAA PF00004.24 EPS26997.1 - 3.9e-15 56.2 0.0 1.2e-14 54.6 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EPS26997.1 - 1.2e-13 51.0 0.0 3e-12 46.4 0.0 2.4 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EPS26997.1 - 4.1e-11 42.2 0.0 8.7e-09 34.5 0.0 2.2 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein Rep_fac_C PF08542.6 EPS26997.1 - 6.2e-11 42.1 0.0 1.1e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Replication factor C C-terminal domain RuvB_N PF05496.7 EPS26997.1 - 1.9e-06 27.1 0.0 4.9e-06 25.7 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EPS26997.1 - 4e-06 26.9 0.0 1.6e-05 25.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPS26997.1 - 5.9e-05 22.7 0.0 0.0002 21.0 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EPS26997.1 - 7e-05 22.8 0.1 0.0016 18.4 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.16 EPS26997.1 - 9.9e-05 21.5 0.0 0.008 15.3 0.0 2.5 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 EPS26997.1 - 0.00013 21.6 0.0 0.00028 20.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EPS26997.1 - 0.00025 20.9 0.0 0.00048 20.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EPS26997.1 - 0.0012 18.4 0.3 0.0044 16.6 0.2 1.9 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EPS26997.1 - 0.0017 17.4 0.0 0.0028 16.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.13 EPS26997.1 - 0.0046 16.4 0.0 0.015 14.7 0.0 1.8 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_5 PF07728.9 EPS26997.1 - 0.0062 16.2 0.1 0.039 13.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EPS26997.1 - 0.0071 15.7 0.1 0.027 13.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 EPS26997.1 - 0.01 14.7 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_17 PF13207.1 EPS26997.1 - 0.016 16.0 0.0 0.048 14.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain DNA_pol3_delta PF06144.8 EPS26997.1 - 0.017 14.6 0.0 0.038 13.4 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit AAA_23 PF13476.1 EPS26997.1 - 0.03 14.6 0.0 0.044 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EPS26997.1 - 0.045 13.1 0.4 0.72 9.2 0.0 2.5 2 1 1 3 3 3 0 AAA-like domain AAA_18 PF13238.1 EPS26997.1 - 0.049 13.9 0.0 0.12 12.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EPS26997.1 - 0.059 13.3 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EPS26997.1 - 0.069 13.0 0.0 0.22 11.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain DEAD PF00270.24 EPS26997.1 - 0.094 12.2 0.0 0.98 8.8 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase PhoH PF02562.11 EPS26997.1 - 0.1 11.7 0.2 5 6.3 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein MCM PF00493.18 EPS26997.1 - 0.11 11.2 0.1 4.7 5.9 0.0 2.3 2 0 0 2 2 2 0 MCM2/3/5 family SNF2_N PF00176.18 EPS26997.1 - 0.11 11.2 0.0 1.6 7.4 0.0 2.1 2 0 0 2 2 2 0 SNF2 family N-terminal domain AAA_3 PF07726.6 EPS26997.1 - 0.11 12.0 0.0 2.5 7.7 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) CLP_protease PF00574.18 EPS27000.1 - 2.6e-75 252.0 0.0 3.3e-75 251.7 0.0 1.0 1 0 0 1 1 1 1 Clp protease Peptidase_S49 PF01343.13 EPS27000.1 - 0.11 12.3 0.5 0.47 10.2 0.3 1.9 1 1 0 1 1 1 0 Peptidase family S49 DUF1746 PF08508.5 EPS27001.1 - 6.2e-38 129.3 2.3 8.7e-38 128.8 1.6 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) Peptidase_M18 PF02127.10 EPS27002.1 - 1.6e-165 550.8 0.0 1.8e-165 550.6 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) WD40 PF00400.27 EPS27004.1 - 2.6e-37 125.3 6.1 5e-07 29.3 0.1 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EPS27004.1 - 5e-09 36.1 0.4 0.0024 17.6 0.0 3.2 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A E3_binding PF02817.12 EPS27005.1 - 6.4e-06 25.7 0.2 0.00012 21.6 0.0 2.7 2 0 0 2 2 2 1 e3 binding domain MreD PF04093.7 EPS27006.1 - 0.0029 17.4 0.4 0.0044 16.8 0.3 1.2 1 0 0 1 1 1 1 rod shape-determining protein MreD DUF2358 PF10184.4 EPS27006.1 - 0.038 13.9 0.0 0.068 13.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) SMC_N PF02463.14 EPS27007.1 - 4e-57 192.9 7.2 3.6e-56 189.8 5.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EPS27007.1 - 6.2e-31 106.8 0.0 2.3e-30 105.0 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EPS27007.1 - 3.9e-11 43.4 1.2 6.3e-07 29.6 0.1 4.6 3 2 2 5 5 5 2 AAA domain AAA_29 PF13555.1 EPS27007.1 - 2.3e-08 33.4 0.0 5e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain MAD PF05557.8 EPS27007.1 - 2e-05 22.9 30.7 2e-05 22.9 21.3 4.4 3 2 1 4 4 4 1 Mitotic checkpoint protein IncA PF04156.9 EPS27007.1 - 0.00011 21.8 15.6 0.00011 21.8 10.8 7.2 3 2 3 6 6 4 1 IncA protein DUF4200 PF13863.1 EPS27007.1 - 0.00054 19.8 7.3 0.00054 19.8 5.0 8.6 4 2 4 8 8 5 1 Domain of unknown function (DUF4200) SbcCD_C PF13558.1 EPS27007.1 - 0.0013 18.5 0.0 0.0066 16.3 0.0 2.3 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit TPR_MLP1_2 PF07926.7 EPS27007.1 - 0.013 15.2 0.2 0.013 15.2 0.1 7.6 5 2 1 6 6 5 0 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 EPS27007.1 - 0.031 13.4 22.6 0.84 8.7 0.1 4.6 3 2 1 5 5 5 0 Reovirus sigma C capsid protein ABC_tran PF00005.22 EPS27007.1 - 1 9.6 0.0 1 9.6 0.0 6.7 4 2 2 6 6 5 0 ABC transporter MtrG PF04210.8 EPS27007.1 - 2.3 7.9 12.5 5.4 6.7 0.0 5.1 3 1 1 4 4 4 0 Tetrahydromethanopterin S-methyltransferase, subunit G Cellulase-like PF12876.2 EPS27008.1 - 0.14 12.6 0.1 0.36 11.3 0.0 1.7 1 0 0 1 1 1 0 Sugar-binding cellulase-like DUF2841 PF11001.3 EPS27010.1 - 2.7e-45 153.2 0.1 4.1e-45 152.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) X PF00739.14 EPS27010.1 - 0.0088 15.9 0.9 0.019 14.8 0.6 1.5 1 0 0 1 1 1 1 Trans-activation protein X Zn_clus PF00172.13 EPS27011.1 - 2e-06 27.6 17.1 3.9e-06 26.6 11.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EPS27011.1 - 0.0013 17.6 0.3 0.0028 16.5 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain CN_hydrolase PF00795.17 EPS27012.1 - 8.6e-32 109.9 0.2 1.2e-31 109.5 0.2 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF2838 PF10998.3 EPS27013.1 - 2.8e-44 149.5 12.7 2.8e-44 149.5 8.8 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF2838) Atg14 PF10186.4 EPS27013.1 - 0.0059 15.5 1.5 0.01 14.7 1.0 1.3 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DUF349 PF03993.7 EPS27013.1 - 0.087 13.0 4.9 0.38 10.9 3.6 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) LETM1 PF07766.8 EPS27014.1 - 7.3e-105 349.8 0.1 1.1e-104 349.1 0.1 1.3 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.22 EPS27014.1 - 6.9e-07 28.6 0.0 0.0023 17.4 0.0 3.0 3 0 0 3 3 3 2 SAP domain NUDIX PF00293.23 EPS27015.1 - 0.0018 17.8 0.2 0.0034 17.0 0.2 1.6 1 1 0 1 1 1 1 NUDIX domain Nucleoplasmin PF03066.10 EPS27016.1 - 0.14 11.6 4.8 0.78 9.2 0.5 2.4 2 0 0 2 2 2 0 Nucleoplasmin Grp1_Fun34_YaaH PF01184.14 EPS27017.1 - 9.2e-54 181.9 14.0 1.2e-53 181.5 9.7 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Glyco_hydro_38 PF01074.17 EPS27018.1 - 4.2e-88 295.1 1.4 4.2e-88 295.1 1.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 EPS27018.1 - 2e-70 237.9 0.0 6.1e-70 236.2 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 EPS27018.1 - 9e-26 89.9 0.0 2e-25 88.7 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Glyco_hydro_57 PF03065.10 EPS27018.1 - 0.015 14.1 0.0 0.039 12.8 0.0 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 NuA4 PF09340.5 EPS27019.1 - 3.2e-27 93.9 0.3 6.4e-27 93.0 0.2 1.5 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 Ctr PF04145.10 EPS27020.1 - 2.6e-34 118.3 2.1 3.7e-34 117.8 1.4 1.2 1 0 0 1 1 1 1 Ctr copper transporter family Wzy_C PF04932.10 EPS27020.1 - 4.5 7.0 6.5 18 5.1 1.1 2.2 2 1 0 2 2 2 0 O-Antigen ligase Cupin_8 PF13621.1 EPS27021.1 - 1.5e-14 54.1 0.1 5.4e-13 49.0 0.0 2.1 1 1 0 1 1 1 1 Cupin-like domain F-box-like PF12937.2 EPS27021.1 - 1.2e-11 44.0 0.0 2.4e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 F-box-like JmjC PF02373.17 EPS27021.1 - 3.3e-10 40.1 0.0 1.5e-09 38.1 0.0 2.0 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box PF00646.28 EPS27021.1 - 4e-08 32.7 0.0 8.4e-08 31.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain DEAD PF00270.24 EPS27022.1 - 7.8e-43 145.8 0.9 1.5e-42 144.9 0.6 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPS27022.1 - 1e-27 95.7 0.5 4.1e-27 93.8 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EPS27022.1 - 0.001 19.1 0.2 0.0034 17.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EPS27022.1 - 0.0022 17.8 0.1 0.0055 16.5 0.1 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EPS27022.1 - 0.0052 16.3 0.1 0.014 14.9 0.0 1.7 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EPS27022.1 - 0.007 16.0 0.1 0.019 14.7 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain CMS1 PF14617.1 EPS27022.1 - 0.017 14.1 0.0 0.036 13.1 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Fanconi_A PF03511.9 EPS27022.1 - 0.091 12.5 0.1 0.21 11.3 0.1 1.6 1 0 0 1 1 1 0 Fanconi anaemia group A protein Avl9 PF09794.4 EPS27023.1 - 0.14 10.5 0.0 0.18 10.2 0.0 1.1 1 0 0 1 1 1 0 Transport protein Avl9 Ank_2 PF12796.2 EPS27024.1 - 0.063 13.6 0.1 0.085 13.2 0.1 1.2 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) efb-c PF12199.3 EPS27024.1 - 0.11 12.3 1.0 0.16 11.8 0.7 1.2 1 0 0 1 1 1 0 Extracellular fibrinogen binding protein C terminal UDPGT PF00201.13 EPS27025.1 - 5.5e-12 45.0 0.0 7.7e-12 44.5 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Adeno_E4_ORF3 PF06931.6 EPS27025.1 - 0.0008 19.4 0.0 0.18 11.8 0.0 2.4 2 0 0 2 2 2 2 Mastadenovirus E4 ORF3 protein Glyco_tran_28_C PF04101.11 EPS27025.1 - 0.048 13.3 0.0 2.2 7.9 0.0 2.3 2 0 0 2 2 2 0 Glycosyltransferase family 28 C-terminal domain TMEM107 PF14995.1 EPS27026.1 - 0.054 13.6 0.1 0.069 13.2 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF1426 PF07234.6 EPS27026.1 - 0.072 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1426) Orbi_NS3 PF01616.11 EPS27026.1 - 0.088 11.7 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Orbivirus NS3 MatE PF01554.13 EPS27027.1 - 1.6e-07 31.0 18.0 0.0012 18.5 0.9 3.8 3 2 0 3 3 3 3 MatE PWI PF01480.12 EPS27028.1 - 2.7e-30 104.2 0.1 4e-30 103.7 0.1 1.3 1 0 0 1 1 1 1 PWI domain Penaeidin PF05927.6 EPS27032.1 - 0.11 13.1 0.1 0.33 11.5 0.0 1.8 2 0 0 2 2 2 0 Penaeidin Pkinase PF00069.20 EPS27034.1 - 2.5e-48 164.4 0.0 3.9e-48 163.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS27034.1 - 1.1e-16 60.7 0.0 1.6e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPS27034.1 - 3.6e-05 22.8 0.0 5.8e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EPS27034.1 - 0.00066 19.0 0.2 0.0014 18.0 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EPS27034.1 - 0.061 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PsaA_PsaB PF00223.14 EPS27034.1 - 0.097 10.7 0.0 0.14 10.1 0.0 1.1 1 0 0 1 1 1 0 Photosystem I psaA/psaB protein Ribosomal_S8e PF01201.17 EPS27035.1 - 9.5e-35 119.6 3.2 5.2e-34 117.2 2.3 2.0 1 1 0 1 1 1 1 Ribosomal protein S8e DUF2390 PF09523.5 EPS27035.1 - 2.4 8.3 7.0 4.6 7.4 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) Tis11B_N PF04553.7 EPS27037.1 - 0.08 13.1 0.4 0.086 13.0 0.3 1.3 1 1 0 1 1 1 0 Tis11B like protein, N terminus Fungal_trans PF04082.13 EPS27038.1 - 1.5e-23 83.0 0.1 2.4e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS27038.1 - 0.0024 17.7 5.4 0.006 16.4 3.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_pol_Rpb4 PF03874.11 EPS27040.1 - 3e-27 94.9 1.9 3.6e-27 94.7 1.3 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 Met_10 PF02475.11 EPS27041.1 - 1.6e-64 217.2 0.0 2.3e-64 216.7 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Pro-kuma_activ PF09286.6 EPS27042.1 - 4.3e-33 114.3 0.1 2.8e-32 111.7 0.0 2.3 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EPS27042.1 - 3.6e-06 26.3 0.1 6.5e-06 25.5 0.1 1.5 1 0 0 1 1 1 1 Subtilase family TMF_DNA_bd PF12329.3 EPS27043.1 - 0.025 14.3 0.9 0.058 13.2 0.6 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DUF1190 PF06693.6 EPS27043.1 - 0.031 14.3 0.4 0.031 14.3 0.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1190) DUF399 PF04187.8 EPS27043.1 - 0.087 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF399 Med11 PF10280.4 EPS27043.1 - 0.19 11.7 2.5 1.5 8.9 0.0 2.7 2 1 1 3 3 3 0 Mediator complex protein DUF3818 PF12825.2 EPS27044.1 - 1.4e-136 454.6 0.9 2e-136 454.1 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EPS27044.1 - 2.2e-42 143.9 0.7 4.7e-42 142.8 0.5 1.5 1 0 0 1 1 1 1 PX-associated PX PF00787.19 EPS27044.1 - 4.1e-14 52.3 0.3 2e-13 50.1 0.0 2.3 2 1 0 2 2 2 1 PX domain DUF3990 PF13151.1 EPS27045.1 - 0.00053 19.4 0.0 0.00085 18.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3990) zf-C2H2 PF00096.21 EPS27047.1 - 0.00068 19.8 18.6 0.0018 18.4 3.5 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPS27047.1 - 0.029 14.6 18.8 0.14 12.6 2.2 3.9 4 0 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EPS27047.1 - 0.031 14.5 16.8 0.045 13.9 1.2 3.4 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.1 EPS27047.1 - 0.055 13.7 12.8 4.2 7.8 1.2 3.7 3 0 0 3 3 3 0 Zinc-finger double domain AAA PF00004.24 EPS27048.1 - 5.7e-48 162.4 0.0 2.6e-43 147.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EPS27048.1 - 6.2e-05 22.4 0.0 0.00033 20.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPS27048.1 - 9.3e-05 23.2 0.0 0.0013 19.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EPS27048.1 - 0.00018 20.6 0.0 0.00044 19.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Parvo_NS1 PF01057.12 EPS27048.1 - 0.00045 19.1 0.0 0.00081 18.3 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_22 PF13401.1 EPS27048.1 - 0.00051 20.1 0.1 0.0067 16.5 0.0 2.9 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 EPS27048.1 - 0.0015 17.9 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 EPS27048.1 - 0.0031 17.4 0.0 0.0078 16.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 EPS27048.1 - 0.0046 17.1 0.0 0.013 15.7 0.0 1.8 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.8 EPS27048.1 - 0.0055 15.4 0.0 0.0093 14.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 EPS27048.1 - 0.0065 16.2 0.0 0.028 14.1 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 EPS27048.1 - 0.019 14.1 0.1 0.045 12.9 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 EPS27048.1 - 0.019 14.9 6.2 0.025 14.5 0.0 3.6 4 1 1 5 5 4 0 AAA ATPase domain AAA_5 PF07728.9 EPS27048.1 - 0.021 14.5 0.0 0.066 12.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) KaiC PF06745.8 EPS27048.1 - 0.03 13.4 0.0 0.068 12.2 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.1 EPS27048.1 - 0.031 14.5 0.0 0.096 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EPS27048.1 - 0.043 13.0 0.0 0.086 12.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.1 EPS27048.1 - 0.13 11.7 0.1 0.23 11.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EPS27048.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Dynamin_M PF01031.15 EPS27048.1 - 0.16 10.7 0.0 0.31 9.7 0.0 1.4 1 0 0 1 1 1 0 Dynamin central region PPV_E1_C PF00519.12 EPS27048.1 - 0.18 10.3 0.0 0.28 9.7 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase RNase_T PF00929.19 EPS27051.1 - 2.5e-20 73.3 0.0 4.1e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EPS27051.1 - 0.0028 17.1 0.0 0.01 15.2 0.0 1.9 1 1 0 1 1 1 1 3'-5' exonuclease Sugar_tr PF00083.19 EPS27052.1 - 4.7e-88 295.7 34.1 5.5e-88 295.5 23.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS27052.1 - 3.3e-27 95.1 68.8 1.5e-24 86.4 27.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EPS27052.1 - 0.00023 19.5 6.1 0.00023 19.5 4.3 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) TPR_19 PF14559.1 EPS27052.1 - 0.024 14.9 0.0 0.055 13.8 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat AA_permease_2 PF13520.1 EPS27055.1 - 9.9e-41 139.6 51.3 1.3e-40 139.2 35.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPS27055.1 - 8.5e-18 63.9 43.8 1.3e-17 63.3 30.3 1.2 1 0 0 1 1 1 1 Amino acid permease Sulfate_transp PF00916.15 EPS27056.1 - 4.1e-05 22.7 0.7 4.1e-05 22.7 0.5 3.6 2 1 1 3 3 3 2 Sulfate transporter family WD40 PF00400.27 EPS27058.1 - 1.5e-12 46.8 9.8 4.8e-07 29.4 0.2 5.3 6 0 0 6 6 6 3 WD domain, G-beta repeat SDP_N PF12278.3 EPS27058.1 - 0.011 15.4 2.6 0.019 14.5 1.8 1.3 1 0 0 1 1 1 0 Sex determination protein N terminal DUF4504 PF14953.1 EPS27058.1 - 0.021 14.1 0.4 0.32 10.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4504) FlxA PF14282.1 EPS27058.1 - 0.038 13.9 4.1 0.16 11.9 2.9 2.0 1 1 0 1 1 1 0 FlxA-like protein Gryzun-like PF12742.2 EPS27058.1 - 0.069 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking IncA PF04156.9 EPS27058.1 - 0.12 11.9 6.2 0.2 11.2 4.3 1.2 1 0 0 1 1 1 0 IncA protein GAS PF13851.1 EPS27058.1 - 0.29 10.3 7.7 0.43 9.7 5.3 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.14 EPS27058.1 - 2.8 5.6 4.7 3.7 5.2 3.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Radical_SAM PF04055.16 EPS27060.1 - 1.2e-14 54.7 0.0 1.9e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily HAD PF12710.2 EPS27061.1 - 7.4e-14 52.3 0.0 1.1e-13 51.8 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EPS27061.1 - 1.7e-09 37.6 0.0 1.8e-08 34.2 0.0 2.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPS27061.1 - 2e-09 38.1 0.1 6.8e-08 33.1 0.0 2.2 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EPS27061.1 - 4.5e-06 26.9 0.0 0.00011 22.4 0.0 2.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EPS27061.1 - 0.008 15.3 0.0 0.11 11.6 0.0 2.1 1 1 0 1 1 1 1 Putative Phosphatase DUF705 PF05152.7 EPS27061.1 - 0.02 13.9 0.1 0.03 13.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF705) S6PP PF05116.8 EPS27061.1 - 0.14 11.4 0.1 0.89 8.8 0.0 2.0 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase PAPS_reduct PF01507.14 EPS27062.1 - 5.2e-44 150.1 0.1 2.2e-43 148.0 0.0 1.8 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family Glyco_hydro_30 PF02055.11 EPS27063.1 - 1.5e-48 165.2 2.6 2.2e-48 164.7 1.8 1.1 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Pkinase PF00069.20 EPS27066.1 - 1e-73 247.7 0.0 1.4e-73 247.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS27066.1 - 4.9e-36 124.1 0.0 7e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 EPS27066.1 - 3.2e-09 36.8 0.0 6.5e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 EPS27066.1 - 1.9e-05 23.7 0.0 3.9e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EPS27066.1 - 0.00014 21.2 0.1 0.00038 19.8 0.1 1.7 1 0 0 1 1 1 1 RIO1 family YukC PF10140.4 EPS27066.1 - 0.0089 14.6 0.1 0.014 13.9 0.1 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC APH PF01636.18 EPS27066.1 - 0.025 14.2 3.2 0.13 11.9 0.0 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EPS27066.1 - 0.19 10.4 0.2 0.31 9.7 0.2 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase UTP15_C PF09384.5 EPS27067.1 - 2e-53 180.0 1.3 2.8e-53 179.6 0.3 1.7 1 1 1 2 2 2 1 UTP15 C terminal WD40 PF00400.27 EPS27067.1 - 2.4e-27 93.7 2.9 1.5e-08 34.2 0.1 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat PQQ_2 PF13360.1 EPS27067.1 - 0.002 17.6 0.6 0.071 12.5 0.0 2.5 2 1 2 4 4 4 1 PQQ-like domain LRS4 PF10422.4 EPS27067.1 - 0.081 12.2 0.7 0.14 11.5 0.5 1.3 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Nup160 PF11715.3 EPS27067.1 - 0.3 9.1 3.7 0.22 9.5 0.3 2.3 2 1 0 2 2 2 0 Nucleoporin Nup120/160 L31 PF09784.4 EPS27067.1 - 1.9 8.6 6.2 0.84 9.7 0.5 3.0 3 0 0 3 3 3 0 Mitochondrial ribosomal protein L31 C2 PF00168.25 EPS27068.1 - 2.1e-10 40.2 0.0 3.5e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 C2 domain PhyH PF05721.8 EPS27069.1 - 7.1e-43 147.1 0.0 8.5e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) RNA_pol_Rpb1_5 PF04998.12 EPS27070.1 - 3.4e-88 295.5 1.6 7.1e-88 294.4 1.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EPS27070.1 - 6.4e-87 291.9 0.2 9.7e-87 291.3 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EPS27070.1 - 6.1e-68 227.9 0.1 1.9e-67 226.3 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EPS27070.1 - 1e-34 119.5 0.0 4.2e-34 117.5 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EPS27070.1 - 1.3e-27 95.6 0.1 5.3e-27 93.6 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 NTS PF15447.1 EPS27070.1 - 0.047 14.0 0.0 0.24 11.8 0.0 2.2 2 0 0 2 2 2 0 N-terminal segments of PfEMP1 Rpr2 PF04032.11 EPS27070.1 - 1.1 9.1 5.7 0.5 10.2 0.7 2.8 3 0 0 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Zn_clus PF00172.13 EPS27071.1 - 2.8e-09 36.7 6.0 5.5e-09 35.7 4.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-CCCH PF00642.19 EPS27072.1 - 0.00044 19.8 1.4 0.0007 19.2 0.9 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EPS27072.1 - 0.081 12.9 4.2 0.15 12.1 2.9 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Sec1 PF00995.18 EPS27073.1 - 1.1e-154 516.2 0.0 1.2e-154 516.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Flavi_DEAD PF07652.9 EPS27073.1 - 0.13 12.0 0.1 0.27 10.9 0.1 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain DUF3718 PF12514.3 EPS27075.1 - 0.073 13.1 0.0 0.21 11.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3718) FYVE PF01363.16 EPS27077.1 - 8.9e-21 73.5 25.0 5.1e-16 58.3 4.4 2.9 3 0 0 3 3 3 2 FYVE zinc finger zf-Di19 PF05605.7 EPS27077.1 - 0.00017 21.6 6.5 0.022 14.8 0.0 2.6 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-AN1 PF01428.11 EPS27077.1 - 0.018 14.9 7.1 0.018 14.9 4.9 3.8 3 1 1 4 4 4 0 AN1-like Zinc finger zf-TFIIB PF13453.1 EPS27077.1 - 0.15 11.3 5.5 5.1 6.3 0.0 3.7 3 0 0 3 3 3 0 Transcription factor zinc-finger IBR PF01485.16 EPS27077.1 - 1.7 8.5 18.7 0.037 13.9 1.7 3.2 4 0 0 4 4 4 0 IBR domain FYVE_2 PF02318.11 EPS27077.1 - 9.4 6.1 14.1 3.1 7.7 2.7 3.2 3 1 0 3 3 3 0 FYVE-type zinc finger GLTP PF08718.6 EPS27079.1 - 3.4e-33 114.7 0.0 4.3e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) PH_4 PF15404.1 EPS27080.1 - 3.2e-59 199.5 0.0 2.3e-58 196.7 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain Spo7_2_N PF15407.1 EPS27080.1 - 2.8e-19 68.3 0.4 6.8e-19 67.1 0.3 1.7 1 0 0 1 1 1 1 Sporulation protein family 7 PH PF00169.24 EPS27080.1 - 1e-08 35.2 0.6 5.7e-05 23.2 0.0 4.1 3 2 0 3 3 3 2 PH domain PH_6 PF15406.1 EPS27080.1 - 0.036 14.1 0.1 1.8 8.6 0.0 2.7 2 0 0 2 2 2 0 Pleckstrin homology domain Peptidase_S24 PF00717.18 EPS27081.1 - 1.1e-08 34.6 0.0 2.3e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EPS27081.1 - 0.005 16.3 0.0 1.2 8.6 0.0 2.8 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Macro PF01661.16 EPS27082.1 - 3.1e-40 136.7 0.5 4.7e-40 136.1 0.3 1.3 1 0 0 1 1 1 1 Macro domain GSK-3_bind PF05350.7 EPS27083.1 - 0.09 12.2 0.6 0.12 11.7 0.4 1.2 1 0 0 1 1 1 0 Glycogen synthase kinase-3 binding p450 PF00067.17 EPS27084.1 - 2.8e-17 62.4 0.0 3.5e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FhuF PF06276.7 EPS27085.1 - 7.8e-12 45.4 0.5 1.1e-05 25.4 0.1 2.3 1 1 1 2 2 2 2 Ferric iron reductase FhuF-like transporter IucA_IucC PF04183.7 EPS27085.1 - 3.5e-11 42.8 0.0 8.4e-11 41.5 0.0 1.6 2 0 0 2 2 2 1 IucA / IucC family GATA PF00320.22 EPS27088.1 - 8.3e-15 53.8 5.2 1.7e-14 52.8 3.6 1.6 1 0 0 1 1 1 1 GATA zinc finger zf-RING_3 PF14369.1 EPS27088.1 - 0.25 11.3 1.9 0.53 10.3 1.3 1.5 1 0 0 1 1 1 0 zinc-finger COesterase PF00135.23 EPS27092.1 - 7.4e-101 338.4 0.1 9.9e-101 338.0 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EPS27092.1 - 3.1e-07 30.1 0.4 4.7e-06 26.3 0.3 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EPS27092.1 - 0.00088 18.5 0.1 0.0015 17.7 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family GCS PF03074.11 EPS27093.1 - 1.1e-154 514.9 0.0 3.7e-154 513.2 0.0 1.7 1 1 0 1 1 1 1 Glutamate-cysteine ligase UPF0278 PF08745.6 EPS27093.1 - 0.11 11.6 0.0 0.41 9.8 0.0 1.8 2 0 0 2 2 2 0 UPF0278 family NDUF_B7 PF05676.8 EPS27094.1 - 1.2e-32 111.1 6.1 1.4e-32 110.8 4.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 EPS27094.1 - 0.0078 15.9 3.5 0.01 15.5 2.5 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Antifungal_prot PF11402.3 EPS27094.1 - 2.3 8.4 6.7 0.94 9.7 2.0 2.1 1 1 1 2 2 2 0 Antifungal protein Ank PF00023.25 EPS27095.1 - 4.6e-16 57.7 1.8 6.6e-11 41.4 0.3 3.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.2 EPS27095.1 - 4.6e-15 55.7 0.7 6.3e-10 39.2 0.5 2.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EPS27095.1 - 1.1e-13 49.9 0.3 6.3e-07 29.0 0.2 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EPS27095.1 - 1.6e-12 47.5 1.2 2.1e-07 31.2 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPS27095.1 - 2.4e-11 43.5 1.0 4.9e-05 23.4 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) KilA-N PF04383.8 EPS27095.1 - 1e-05 25.1 0.0 3.4e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 KilA-N domain GGDN PF05165.7 EPS27095.1 - 0.036 13.0 0.0 0.069 12.1 0.0 1.4 1 0 0 1 1 1 0 GGDN family CDC37_N PF03234.9 EPS27095.1 - 0.27 11.5 4.7 0.084 13.1 0.6 2.4 2 1 0 2 2 2 0 Cdc37 N terminal kinase binding DUF2322 PF10084.4 EPS27096.1 - 0.0068 16.1 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2322) DUF1212 PF06738.7 EPS27097.1 - 1.1e-54 184.8 13.6 1.7e-50 171.2 0.2 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EPS27097.1 - 1e-30 106.3 12.0 1e-30 106.3 8.3 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3815) MIS13 PF08202.6 EPS27098.1 - 1e-41 142.9 12.0 4.5e-41 140.8 3.4 3.1 2 1 0 2 2 2 1 Mis12-Mtw1 protein family TSC22 PF01166.13 EPS27098.1 - 0.013 15.4 0.8 0.029 14.3 0.5 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family DivIC PF04977.10 EPS27098.1 - 0.14 11.6 1.5 0.3 10.6 1.1 1.5 1 0 0 1 1 1 0 Septum formation initiator Sds3 PF08598.6 EPS27098.1 - 9 5.7 13.3 0.23 10.9 0.2 2.6 3 0 0 3 3 3 0 Sds3-like PS_Dcarbxylase PF02666.10 EPS27099.1 - 2.9e-51 173.6 0.0 4.3e-51 173.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 EPS27099.1 - 1.6e-17 63.0 0.1 9e-15 54.2 0.1 2.5 2 0 0 2 2 2 2 C2 domain EF-hand_7 PF13499.1 EPS27099.1 - 0.0063 16.6 0.1 0.021 14.9 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EPS27099.1 - 0.018 14.2 0.1 0.057 12.7 0.1 1.9 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 EPS27099.1 - 0.063 13.1 0.1 0.37 10.7 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain APH PF01636.18 EPS27100.1 - 1.7e-11 44.3 0.1 2.3e-11 43.8 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPS27100.1 - 0.0057 16.2 0.0 0.0084 15.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Sugar_tr PF00083.19 EPS27101.1 - 6.6e-93 311.7 15.1 8.4e-93 311.3 10.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS27101.1 - 2.4e-35 121.9 39.1 4.1e-26 91.5 8.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EPS27101.1 - 7.9e-06 24.3 2.4 7.9e-06 24.3 1.7 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Pkinase PF00069.20 EPS27103.1 - 4.6e-62 209.5 0.0 6e-62 209.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS27103.1 - 2.3e-29 102.2 0.0 3.6e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPS27103.1 - 0.012 14.5 0.0 0.023 13.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like zf-UBR PF02207.15 EPS27104.1 - 8.4e-17 60.6 4.5 8.4e-17 60.6 3.1 3.2 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) MCM PF00493.18 EPS27105.1 - 3e-138 460.1 0.1 4e-138 459.7 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 EPS27105.1 - 6.5e-34 117.1 40.8 6.5e-34 117.1 28.3 2.5 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 EPS27105.1 - 2.7e-17 63.3 0.1 7.2e-17 62.0 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EPS27105.1 - 4.8e-09 35.6 0.1 7.6e-07 28.4 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EPS27105.1 - 7.9e-06 25.6 0.0 1.6e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EPS27105.1 - 0.00099 18.7 0.0 0.0062 16.1 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EPS27105.1 - 0.001 18.5 0.1 0.0062 16.0 0.1 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain Zn_ribbon_2 PF12674.2 EPS27105.1 - 0.014 15.7 0.3 0.048 14.0 0.2 1.9 1 0 0 1 1 1 0 Putative zinc ribbon domain Pal1 PF08316.6 EPS27106.1 - 4.3e-49 166.5 2.5 2.7e-48 163.9 1.7 2.3 1 1 0 1 1 1 1 Pal1 cell morphology protein Tannase PF07519.6 EPS27108.1 - 8e-100 334.7 0.7 9.6e-100 334.5 0.5 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.16 EPS27108.1 - 0.017 14.3 0.2 1.6 7.8 0.0 2.6 2 1 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EPS27108.1 - 0.038 13.7 0.0 0.11 12.2 0.0 1.9 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_2 PF07486.7 EPS27108.1 - 0.072 13.6 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Cell Wall Hydrolase Med31 PF05669.7 EPS27109.1 - 7.6e-30 102.6 0.0 8.9e-30 102.4 0.0 1.0 1 0 0 1 1 1 1 SOH1 DUF4551 PF15087.1 EPS27110.1 - 0.63 8.3 2.2 1.1 7.5 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Palm_thioest PF02089.10 EPS27111.1 - 3.7e-55 186.8 0.0 4.5e-55 186.5 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.6 EPS27111.1 - 0.0081 15.2 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) zf-C2H2_4 PF13894.1 EPS27113.1 - 0.043 14.1 1.8 0.043 14.1 1.2 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EPS27113.1 - 7.8 7.0 9.2 4.1 7.9 0.3 3.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type KTI12 PF08433.5 EPS27114.1 - 3e-62 210.2 0.0 6.3e-62 209.2 0.0 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 EPS27114.1 - 0.00012 21.9 0.1 0.00025 20.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain Methyltransf_16 PF10294.4 EPS27115.1 - 4.1e-14 52.4 0.0 6.6e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EPS27115.1 - 0.001 18.8 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DUF605 PF04652.11 EPS27117.1 - 9.4 5.5 15.9 12 5.2 11.0 1.0 1 0 0 1 1 1 0 Vta1 like Peptidase_C14 PF00656.17 EPS27120.1 - 1.5e-69 234.4 0.0 1.9e-69 234.1 0.0 1.0 1 0 0 1 1 1 1 Caspase domain F-box-like PF12937.2 EPS27121.1 - 0.0074 15.9 0.7 0.021 14.5 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EPS27121.1 - 0.053 13.1 4.4 0.059 13.0 0.1 2.6 3 0 0 3 3 3 0 F-box domain bZIP_1 PF00170.16 EPS27122.1 - 1.9e-08 34.1 14.5 9.4e-07 28.7 6.6 2.3 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 EPS27122.1 - 4.1e-05 23.3 20.1 0.0085 15.9 6.8 2.4 1 1 1 2 2 2 2 Basic region leucine zipper ATG16 PF08614.6 EPS27122.1 - 0.00065 19.5 10.5 0.001 18.9 7.3 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) bZIP_Maf PF03131.12 EPS27122.1 - 0.0018 18.5 14.3 0.0018 18.5 7.9 2.2 1 1 1 2 2 2 1 bZIP Maf transcription factor IncA PF04156.9 EPS27122.1 - 0.0021 17.6 10.4 0.003 17.1 7.2 1.3 1 0 0 1 1 1 1 IncA protein DUF724 PF05266.9 EPS27122.1 - 0.0086 15.7 5.5 0.017 14.7 3.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF724) DUF1640 PF07798.6 EPS27122.1 - 0.011 15.8 4.4 0.018 15.0 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) TBPIP PF07106.8 EPS27122.1 - 0.015 14.8 6.8 0.025 14.1 4.7 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TMF_TATA_bd PF12325.3 EPS27122.1 - 0.02 14.5 8.0 0.044 13.5 5.5 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding COG5 PF10392.4 EPS27122.1 - 0.021 14.8 3.3 0.041 13.8 2.3 1.5 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DUF972 PF06156.8 EPS27122.1 - 0.022 15.0 7.7 0.024 14.9 4.2 1.9 2 1 0 2 2 1 0 Protein of unknown function (DUF972) FUSC PF04632.7 EPS27122.1 - 0.022 13.1 1.2 0.028 12.8 0.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family HALZ PF02183.13 EPS27122.1 - 0.044 13.5 0.6 0.044 13.5 0.4 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF4559 PF15112.1 EPS27122.1 - 0.055 12.6 3.8 0.07 12.2 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) SPX PF03105.14 EPS27122.1 - 0.062 13.0 5.9 0.071 12.8 4.1 1.2 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.4 EPS27122.1 - 0.073 11.3 8.4 0.08 11.2 5.8 1.0 1 0 0 1 1 1 0 Transmembrane protein Put_DNA-bind_N PF06971.8 EPS27122.1 - 0.094 12.4 0.0 6.9 6.5 0.0 2.5 2 0 0 2 2 2 0 Putative DNA-binding protein N-terminus Seryl_tRNA_N PF02403.17 EPS27122.1 - 0.1 12.5 8.5 0.17 11.8 5.9 1.3 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ADIP PF11559.3 EPS27122.1 - 0.13 12.1 11.7 0.21 11.4 8.1 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding APG6 PF04111.7 EPS27122.1 - 0.14 11.2 8.6 0.21 10.6 6.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Cep57_CLD_2 PF14197.1 EPS27122.1 - 0.16 11.8 10.7 0.34 10.8 7.4 1.6 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Sec34 PF04136.10 EPS27122.1 - 0.18 11.4 3.1 0.44 10.2 1.6 1.9 2 0 0 2 2 2 0 Sec34-like family V_ATPase_I PF01496.14 EPS27122.1 - 0.18 9.5 3.3 0.22 9.3 2.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Glutaredoxin2_C PF04399.8 EPS27122.1 - 0.25 10.9 2.7 0.58 9.7 1.9 1.6 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain OmpH PF03938.9 EPS27122.1 - 0.3 11.0 7.8 0.58 10.0 5.4 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Viral_P18 PF04521.8 EPS27122.1 - 0.51 9.7 5.9 0.15 11.5 1.7 1.9 3 0 0 3 3 1 0 ssRNA positive strand viral 18kD cysteine rich protein DUF904 PF06005.7 EPS27122.1 - 0.52 10.6 12.0 0.84 9.9 7.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Rootletin PF15035.1 EPS27122.1 - 0.75 9.7 16.8 17 5.3 11.6 2.1 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Mst1_SARAH PF11629.3 EPS27122.1 - 1 9.2 5.3 29 4.5 0.1 3.7 3 1 1 4 4 3 0 C terminal SARAH domain of Mst1 DUF4446 PF14584.1 EPS27122.1 - 1.1 9.1 4.8 1.4 8.7 3.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) Mto2_bdg PF12808.2 EPS27122.1 - 1.2 9.2 14.2 0.23 11.5 0.7 2.6 1 1 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF349 PF03993.7 EPS27122.1 - 2.7 8.2 7.8 4.5 7.4 5.4 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) DUF342 PF03961.8 EPS27122.1 - 3 6.1 5.6 4.1 5.6 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DivIC PF04977.10 EPS27122.1 - 4.1 6.9 10.7 0.68 9.4 2.9 2.3 1 1 1 2 2 2 0 Septum formation initiator DUF3712 PF12505.3 EPS27124.1 - 6.9e-33 113.3 2.0 1.5e-32 112.2 1.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) DUF3328 PF11807.3 EPS27124.1 - 0.066 12.8 0.0 0.36 10.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) DUF2236 PF09995.4 EPS27125.1 - 7.9e-42 143.2 5.9 9.6e-42 142.9 4.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) MDMPI_C PF07398.6 EPS27125.1 - 0.0093 16.5 0.1 0.088 13.3 0.0 2.3 2 1 0 2 2 2 1 MDMPI C-terminal domain DEC-1_N PF04625.8 EPS27126.1 - 1.4 7.5 4.2 1.9 7.0 2.9 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region SOBP PF15279.1 EPS27126.1 - 3.6 7.8 6.5 4.6 7.5 4.5 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein CsbD PF05532.7 EPS27128.1 - 3.1e-18 65.1 22.9 3.9e-11 42.4 3.8 3.4 3 1 0 3 3 3 2 CsbD-like IDO PF01231.13 EPS27129.1 - 6.2e-167 555.3 0.0 7.1e-167 555.1 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.6 EPS27129.1 - 0.025 13.1 0.0 0.074 11.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1864) AA_permease_2 PF13520.1 EPS27131.1 - 8.7e-50 169.4 42.0 1.1e-49 169.1 29.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPS27131.1 - 6e-23 80.9 36.9 8.1e-23 80.4 25.6 1.1 1 0 0 1 1 1 1 Amino acid permease MgtE PF01769.11 EPS27132.1 - 0.002 18.4 0.1 0.002 18.4 0.1 3.4 1 1 3 4 4 4 1 Divalent cation transporter Aminotran_5 PF00266.14 EPS27133.1 - 4.8e-96 321.7 0.0 6.1e-96 321.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EPS27133.1 - 3.2e-08 33.0 0.0 5.8e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EPS27133.1 - 8.2e-05 21.7 0.0 0.0002 20.5 0.0 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family BAR PF03114.13 EPS27134.1 - 6.6e-63 212.2 9.6 8.2e-63 211.9 6.6 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EPS27134.1 - 5.3e-15 54.5 0.1 1.1e-14 53.5 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EPS27134.1 - 5.8e-13 48.2 0.1 9.8e-13 47.4 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EPS27134.1 - 4.6e-11 42.0 1.2 6.6e-11 41.5 0.0 1.9 3 0 0 3 3 3 1 Variant SH3 domain Vps5 PF09325.5 EPS27134.1 - 0.0036 16.5 8.0 0.35 10.0 0.1 2.3 2 0 0 2 2 2 2 Vps5 C terminal like AHS1 PF02682.11 EPS27134.1 - 0.041 13.3 0.4 0.086 12.2 0.3 1.5 1 0 0 1 1 1 0 Allophanate hydrolase subunit 1 UBA PF00627.26 EPS27134.1 - 0.061 13.1 0.2 0.75 9.7 0.1 2.5 2 0 0 2 2 2 0 UBA/TS-N domain APG6 PF04111.7 EPS27134.1 - 0.14 11.1 7.7 2.2 7.2 2.7 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 YlqD PF11068.3 EPS27134.1 - 0.79 9.7 7.5 0.67 10.0 0.1 2.6 3 0 0 3 3 3 0 YlqD protein TMPIT PF07851.8 EPS27134.1 - 1 8.3 7.8 0.18 10.8 0.1 2.1 1 1 1 2 2 2 0 TMPIT-like protein BRE1 PF08647.6 EPS27134.1 - 1.3 9.0 9.9 0.27 11.2 0.6 2.7 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase STE2 PF02116.10 EPS27135.1 - 1e-96 323.3 15.5 1.2e-96 323.0 10.7 1.1 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR DUF3852 PF12963.2 EPS27135.1 - 0.16 12.0 5.9 0.032 14.2 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3852) HNH_2 PF13391.1 EPS27136.1 - 0.01 15.6 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease PYRIN PF02758.11 EPS27136.1 - 0.093 12.4 0.1 0.22 11.2 0.0 1.7 2 1 0 2 2 2 0 PAAD/DAPIN/Pyrin domain Oxidored_FMN PF00724.15 EPS27137.1 - 8.3e-72 242.0 0.0 1e-71 241.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family UEV PF05743.8 EPS27138.1 - 7.8e-40 135.3 0.1 1.4e-39 134.5 0.1 1.4 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 EPS27138.1 - 6.3e-22 76.9 0.0 1.5e-21 75.7 0.0 1.7 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.21 EPS27138.1 - 0.0012 18.2 0.1 0.0012 18.2 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Sipho_Gp157 PF05565.6 EPS27138.1 - 0.041 13.4 0.0 0.065 12.8 0.0 1.2 1 0 0 1 1 1 0 Siphovirus Gp157 Striatin PF08232.7 EPS27138.1 - 0.14 12.4 0.1 0.25 11.6 0.1 1.3 1 0 0 1 1 1 0 Striatin family APH PF01636.18 EPS27139.1 - 0.0069 16.1 0.0 0.0096 15.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family HipA_N PF07805.7 EPS27139.1 - 0.039 14.1 0.0 0.099 12.8 0.0 1.7 1 1 0 1 1 1 0 HipA-like N-terminal domain Fructosamin_kin PF03881.9 EPS27139.1 - 0.042 12.8 0.0 0.052 12.5 0.0 1.1 1 0 0 1 1 1 0 Fructosamine kinase Chitin_synth_1 PF01644.12 EPS27140.1 - 1.8e-67 226.1 0.0 2.7e-67 225.6 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EPS27140.1 - 8.9e-28 95.8 0.0 1.6e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EPS27140.1 - 4.3e-26 91.4 0.0 1.8e-21 76.1 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EPS27140.1 - 2.8e-12 46.7 0.1 2.8e-12 46.7 0.0 2.8 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EPS27140.1 - 1.9e-09 37.6 0.0 6e-09 36.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 UQ_con PF00179.21 EPS27141.1 - 2e-38 130.9 0.0 2.9e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EPS27141.1 - 0.023 14.4 0.0 0.025 14.3 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B APH PF01636.18 EPS27142.1 - 4.3e-14 52.8 0.0 7.3e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPS27142.1 - 0.0011 18.5 0.0 0.0041 16.7 0.0 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase DUF1679 PF07914.6 EPS27142.1 - 0.0092 14.6 0.0 0.17 10.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.9 EPS27142.1 - 0.09 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase TAF8_C PF10406.4 EPS27144.1 - 7.8e-23 80.2 0.2 2.3e-22 78.7 0.1 1.9 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.8 EPS27144.1 - 1.7e-06 27.6 0.0 3.7e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated Mitochondr_Som1 PF11093.3 EPS27145.1 - 7.2e-10 38.5 0.1 9.3e-10 38.1 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial export protein Som1 AAA_25 PF13481.1 EPS27146.1 - 0.00011 21.6 0.0 0.0013 18.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain PALP PF00291.20 EPS27147.1 - 1.3e-77 261.1 0.3 1.8e-77 260.6 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EPS27147.1 - 0.039 12.9 0.1 0.066 12.2 0.1 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family NAD_binding_2 PF03446.10 EPS27147.1 - 0.046 13.5 0.1 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EPS27148.1 - 1.1e-45 154.9 0.0 1.7e-45 154.3 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 EPS27148.1 - 4.6e-45 153.0 0.0 7.3e-45 152.4 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 EPS27148.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Isochorismatase PF00857.15 EPS27149.1 - 3.7e-24 85.5 0.0 3.5e-23 82.4 0.0 2.3 1 1 0 1 1 1 1 Isochorismatase family 2OG-FeII_Oxy_2 PF13532.1 EPS27149.1 - 1.5e-23 83.6 0.0 2.9e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GST_C_3 PF14497.1 EPS27149.1 - 5.3e-06 26.8 0.0 1.4e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EPS27149.1 - 9.9e-05 22.1 0.1 0.00045 20.0 0.1 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EPS27149.1 - 0.063 13.2 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.8 EPS27149.1 - 0.19 11.3 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain Lipase_GDSL PF00657.17 EPS27150.1 - 1.2e-14 54.6 0.5 1.6e-14 54.3 0.3 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EPS27150.1 - 2.5e-12 47.2 0.9 3.7e-12 46.7 0.6 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF1330 PF07045.6 EPS27150.1 - 0.081 12.7 0.3 3.9 7.3 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1330) ECH PF00378.15 EPS27151.1 - 6.4e-39 133.5 0.9 1.2e-38 132.6 0.6 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family HSP20 PF00011.16 EPS27152.1 - 3.2e-18 65.4 0.2 1.3e-16 60.3 0.1 2.1 1 1 0 1 1 1 1 Hsp20/alpha crystallin family Tbf5 PF06331.7 EPS27153.1 - 1.9e-24 85.2 1.3 2.2e-24 85.0 0.9 1.1 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 DUF1325 PF07039.6 EPS27153.1 - 0.029 13.9 0.2 0.032 13.8 0.2 1.1 1 0 0 1 1 1 0 SGF29 tudor-like domain MFS_1 PF07690.11 EPS27155.1 - 8.9e-37 126.5 57.2 1.7e-36 125.6 39.7 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2937 PF11157.3 EPS27155.1 - 7.9 5.7 14.2 0.25 10.6 1.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2937) HRXXH PF13933.1 EPS27156.1 - 2.7e-105 351.2 0.0 3.6e-105 350.8 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family NAGLU PF05089.7 EPS27157.1 - 6.9e-129 429.3 8.6 9.1e-129 428.9 6.0 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.2 EPS27157.1 - 2.4e-68 230.3 8.2 3.8e-68 229.7 5.7 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.2 EPS27157.1 - 5e-17 61.3 0.0 1.1e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Glyco_hydro_11 PF00457.12 EPS27158.1 - 2.9e-72 241.8 19.3 4.8e-72 241.1 13.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 CBM_1 PF00734.13 EPS27158.1 - 1.4e-09 37.4 19.5 1.4e-09 37.4 13.5 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain Toxin_7 PF05980.7 EPS27158.1 - 0.025 14.6 9.8 0.047 13.7 6.8 1.5 1 0 0 1 1 1 0 Toxin 7 CBM_1 PF00734.13 EPS27159.1 - 5.7e-13 48.2 8.0 5.7e-13 48.2 5.6 3.4 4 0 0 4 4 4 1 Fungal cellulose binding domain Pollen_allerg_1 PF01357.16 EPS27159.1 - 1.2e-06 28.1 0.1 1.1e-05 25.1 0.1 2.2 1 1 0 1 1 1 1 Pollen allergen Y_phosphatase3C PF13348.1 EPS27160.1 - 0.058 13.4 0.0 0.092 12.8 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family C-terminal region MT0933_antitox PF14013.1 EPS27160.1 - 0.24 11.5 1.8 0.72 10.0 1.3 2.1 1 1 0 1 1 1 0 MT0933-like antitoxin protein TPR_12 PF13424.1 EPS27161.1 - 4.6e-26 90.5 23.0 1.1e-09 38.0 1.4 5.3 4 1 1 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 EPS27161.1 - 1.2e-08 34.5 30.3 0.042 13.7 0.7 7.3 7 1 0 7 7 7 4 Tetratricopeptide repeat PGAP1 PF07819.8 EPS27161.1 - 2e-06 27.5 0.0 4.3e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein TPR_11 PF13414.1 EPS27161.1 - 7.1e-06 25.5 9.0 0.011 15.3 0.1 3.9 4 0 0 4 4 4 2 TPR repeat Abhydrolase_6 PF12697.2 EPS27161.1 - 5.5e-05 23.1 0.1 0.00017 21.5 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.9 EPS27161.1 - 0.00012 21.4 0.0 0.00023 20.5 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) TPR_8 PF13181.1 EPS27161.1 - 0.00013 21.5 9.7 0.15 11.9 0.4 4.5 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EPS27161.1 - 0.00023 21.5 22.0 0.29 11.8 0.2 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 EPS27161.1 - 0.00061 20.3 21.4 0.2 12.3 0.2 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EPS27161.1 - 0.0027 17.3 0.3 0.0027 17.3 0.2 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 EPS27161.1 - 0.0035 17.1 1.2 0.0035 17.1 0.8 5.8 6 0 0 6 6 5 1 Tetratricopeptide repeat Abhydrolase_5 PF12695.2 EPS27161.1 - 0.0048 16.6 0.0 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family TPR_19 PF14559.1 EPS27161.1 - 0.0059 16.9 17.6 1.2 9.5 0.1 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat Lipase_3 PF01764.20 EPS27161.1 - 0.0065 16.0 0.0 0.055 13.0 0.0 2.3 2 0 0 2 2 2 1 Lipase (class 3) TPR_1 PF00515.23 EPS27161.1 - 0.016 14.7 1.6 0.016 14.7 1.1 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF2664 PF10867.3 EPS27161.1 - 0.03 14.9 4.1 0.85 10.2 0.2 4.1 3 1 1 4 4 4 0 Protein of unknown function (DUF2664) Cutinase PF01083.17 EPS27161.1 - 0.05 13.3 0.0 0.098 12.3 0.0 1.4 1 0 0 1 1 1 0 Cutinase Cu_amine_oxid PF01179.15 EPS27162.1 - 7.2e-164 545.4 0.1 8.8e-164 545.1 0.1 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EPS27162.1 - 1.4e-05 25.0 0.0 2.8e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EPS27162.1 - 0.0011 19.0 0.1 0.0026 17.7 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Abhydrolase_6 PF12697.2 EPS27163.1 - 2e-26 93.3 0.1 2.4e-26 93.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPS27163.1 - 1.7e-16 60.5 0.0 1.1e-15 57.7 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPS27163.1 - 9.7e-13 48.1 0.0 2.4e-12 46.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EPS27163.1 - 0.0022 17.4 0.0 0.085 12.2 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase PhoPQ_related PF10142.4 EPS27163.1 - 0.0035 15.8 0.0 0.0054 15.2 0.0 1.2 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Hydrolase_4 PF12146.3 EPS27163.1 - 0.016 15.0 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Ndr PF03096.9 EPS27163.1 - 0.044 12.2 0.0 0.17 10.3 0.0 1.9 1 1 0 1 1 1 0 Ndr family Peptidase_S9 PF00326.16 EPS27163.1 - 0.067 12.4 0.0 1.1 8.4 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 EPS27163.1 - 0.072 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 EPS27163.1 - 0.13 10.6 0.0 0.55 8.6 0.0 1.9 2 1 0 2 2 2 0 Acetyl xylan esterase (AXE1) MFS_1 PF07690.11 EPS27164.1 - 2.4e-27 95.6 55.1 1.4e-23 83.1 24.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS27164.1 - 3.2e-16 58.9 26.8 2.3e-13 49.5 5.1 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter Glyco_hydro_3 PF00933.16 EPS27165.1 - 3.3e-75 252.8 0.0 5e-75 252.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EPS27165.1 - 1e-58 198.5 0.0 1.5e-58 198.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EPS27165.1 - 3.2e-22 78.2 0.0 6.7e-22 77.2 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 EPS27165.1 - 8.4e-16 57.9 0.0 2e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 PA14 domain Sugar_tr PF00083.19 EPS27166.1 - 2.2e-68 230.9 21.5 3e-68 230.4 14.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS27166.1 - 1.3e-20 73.3 28.0 5.4e-20 71.4 11.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EPS27166.1 - 0.0072 14.5 2.1 0.011 13.9 1.5 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Chal_sti_synt_N PF00195.14 EPS27167.1 - 1.7e-32 112.5 0.1 5.1e-32 110.9 0.0 1.7 2 0 0 2 2 2 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.10 EPS27167.1 - 8.9e-19 67.9 0.0 2e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain FAE1_CUT1_RppA PF08392.7 EPS27167.1 - 7.9e-09 34.9 0.1 1.4e-08 34.2 0.1 1.3 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III PF08545.5 EPS27167.1 - 3e-07 30.0 1.9 5.9e-07 29.0 0.7 2.0 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.5 EPS27167.1 - 0.00047 20.1 0.1 0.003 17.5 0.0 2.4 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal RDM PF11002.3 EPS27167.1 - 0.15 11.7 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 RFPL defining motif (RDM) Sulfotransfer_3 PF13469.1 EPS27168.1 - 0.0022 18.9 1.3 0.0045 17.9 0.7 1.7 1 1 0 1 1 1 1 Sulfotransferase family DUF1206 PF06724.6 EPS27170.1 - 0.065 12.9 6.0 1.2 8.9 0.1 3.0 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1206) SHR3_chaperone PF08229.6 EPS27170.1 - 0.076 11.9 0.7 0.18 10.7 0.5 1.7 1 1 0 1 1 1 0 ER membrane protein SH3 Cas_Cmr3 PF09700.5 EPS27170.1 - 0.2 11.0 0.0 0.27 10.6 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cmr3) Lig_chan PF00060.21 EPS27170.1 - 1.7 8.3 6.6 3.9 7.1 4.6 1.6 1 0 0 1 1 1 0 Ligand-gated ion channel DUF4383 PF14325.1 EPS27170.1 - 3.8 7.5 8.7 1.3 9.0 0.8 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4383) p450 PF00067.17 EPS27171.1 - 2.8e-51 174.4 0.0 3.5e-51 174.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2651 PF10852.3 EPS27172.1 - 0.029 14.7 1.6 1.4 9.3 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2651) DUF1772 PF08592.6 EPS27172.1 - 0.82 9.4 13.4 0.021 14.5 3.2 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) DUF2909 PF11137.3 EPS27172.1 - 0.93 9.2 5.7 1.6 8.5 1.9 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2909) TRAM_LAG1_CLN8 PF03798.11 EPS27172.1 - 4.4 6.7 8.4 4.4 6.8 0.5 2.5 1 1 0 2 2 2 0 TLC domain DUF4234 PF14018.1 EPS27172.1 - 5.1 6.9 6.7 22 4.8 1.5 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) DUF3632 PF12311.3 EPS27173.1 - 1.3e-28 100.0 2.0 1.7e-28 99.6 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) AraC_binding PF02311.14 EPS27173.1 - 0.16 11.6 0.3 0.44 10.2 0.1 1.8 2 0 0 2 2 2 0 AraC-like ligand binding domain FliT PF05400.8 EPS27173.1 - 0.18 12.1 3.2 9 6.7 0.3 3.4 3 0 0 3 3 3 0 Flagellar protein FliT Ribonuclease PF00545.15 EPS27174.1 - 8.2e-14 51.4 0.4 1e-13 51.1 0.3 1.2 1 0 0 1 1 1 1 ribonuclease DUF3892 PF13031.1 EPS27174.1 - 0.043 14.2 0.0 0.13 12.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3892) DUF2713 PF10897.3 EPS27174.1 - 0.1 11.8 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2713) FAD_binding_3 PF01494.14 EPS27175.1 - 1.9e-17 63.3 0.0 1.3e-08 34.3 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EPS27175.1 - 3.2e-11 42.7 0.1 2.9e-06 26.4 0.1 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase GIDA PF01134.17 EPS27175.1 - 2.5e-06 26.6 0.0 6.9e-06 25.1 0.0 1.6 1 1 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EPS27175.1 - 1.8e-05 24.6 0.1 3.9e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EPS27175.1 - 1.8e-05 25.0 0.0 0.007 16.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EPS27175.1 - 0.00037 19.4 0.4 0.0028 16.5 0.2 2.2 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.9 EPS27175.1 - 0.00062 19.6 0.0 0.0012 18.7 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EPS27175.1 - 0.0023 16.4 0.1 0.006 15.0 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein Trp_halogenase PF04820.9 EPS27175.1 - 0.0026 16.4 0.0 0.0053 15.4 0.0 1.5 2 0 0 2 2 2 1 Tryptophan halogenase SE PF08491.5 EPS27175.1 - 0.0028 16.5 0.0 1.1 8.0 0.0 2.3 3 0 0 3 3 3 2 Squalene epoxidase Lycopene_cycl PF05834.7 EPS27175.1 - 0.005 15.8 0.2 0.011 14.6 0.1 1.7 1 1 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.2 EPS27175.1 - 0.0067 15.5 0.1 0.019 14.0 0.1 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EPS27175.1 - 0.056 13.0 0.0 0.095 12.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Rab3-GTPase_cat PF13890.1 EPS27175.1 - 0.079 12.3 0.2 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 Rab3 GTPase-activating protein catalytic subunit Methyltransf_2 PF00891.13 EPS27176.1 - 4.1e-31 108.0 0.0 7.5e-31 107.1 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 EPS27176.1 - 0.00023 20.8 0.1 0.00056 19.6 0.1 1.7 1 0 0 1 1 1 1 Dimerisation domain p450 PF00067.17 EPS27178.1 - 2.1e-31 108.9 0.0 3.1e-31 108.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF258 PF03193.11 EPS27178.1 - 0.15 11.2 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Methyltransf_2 PF00891.13 EPS27180.1 - 7.9e-31 107.0 0.0 2.1e-30 105.6 0.0 1.7 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_23 PF13489.1 EPS27180.1 - 6.2e-05 22.7 0.0 0.00014 21.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Dimerisation PF08100.6 EPS27180.1 - 0.019 14.7 0.4 0.084 12.7 0.0 2.3 3 0 0 3 3 3 0 Dimerisation domain Methyltransf_19 PF04672.7 EPS27180.1 - 0.081 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl methyltransferase Cytochrom_B561 PF03188.11 EPS27183.1 - 2.8e-10 40.1 0.7 3.7e-10 39.7 0.4 1.4 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 tRNA-synt_2b PF00587.20 EPS27184.1 - 6.2e-06 25.8 0.0 1.1e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Cu-oxidase_3 PF07732.10 EPS27185.1 - 6.1e-31 106.5 0.2 1.8e-30 105.1 0.1 1.8 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.17 EPS27185.1 - 3.8e-26 91.8 0.0 7.2e-24 84.4 0.0 2.3 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EPS27185.1 - 6.6e-17 61.3 8.3 3.9e-14 52.3 1.0 3.3 2 1 0 2 2 2 2 Multicopper oxidase SseC PF04888.7 EPS27186.1 - 0.02 14.2 6.0 0.021 14.1 4.2 1.0 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family YpjP PF14005.1 EPS27186.1 - 0.036 13.8 1.2 0.039 13.7 0.8 1.1 1 0 0 1 1 1 0 YpjP-like protein Flexi_CP PF00286.15 EPS27186.1 - 0.09 12.4 3.3 0.097 12.3 2.3 1.1 1 0 0 1 1 1 0 Viral coat protein Mor PF08765.6 EPS27186.1 - 0.26 11.0 1.0 0.61 9.8 0.3 1.8 1 1 0 1 1 1 0 Mor transcription activator family Cauli_DNA-bind PF03310.8 EPS27186.1 - 0.57 10.0 4.1 0.65 9.8 2.9 1.2 1 0 0 1 1 1 0 Caulimovirus DNA-binding protein HK97-gp10_like PF04883.7 EPS27186.1 - 0.83 10.6 4.6 1.2 10.1 3.2 1.3 1 1 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component ABC_tran PF00005.22 EPS27187.1 - 6.2e-43 146.3 1.0 3.4e-25 88.9 0.1 3.5 3 1 0 3 3 3 2 ABC transporter ABC_membrane PF00664.18 EPS27187.1 - 4.6e-32 111.5 27.2 1.7e-21 76.9 9.5 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EPS27187.1 - 3.9e-13 49.1 2.0 0.003 16.8 1.5 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EPS27187.1 - 1.2e-06 28.7 0.5 0.014 15.3 0.0 4.5 4 1 1 5 5 4 1 AAA domain AAA_16 PF13191.1 EPS27187.1 - 2.2e-06 27.7 2.2 0.011 15.6 0.4 2.9 2 0 0 2 2 2 2 AAA ATPase domain T2SE PF00437.15 EPS27187.1 - 7.2e-06 25.0 0.1 0.019 13.8 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA PF00004.24 EPS27187.1 - 0.0001 22.5 0.2 0.2 11.8 0.0 3.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 EPS27187.1 - 0.00011 22.6 0.1 0.17 12.3 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 EPS27187.1 - 0.0011 19.1 0.9 3.1 7.9 0.1 3.3 3 1 0 3 3 2 2 AAA domain cobW PF02492.14 EPS27187.1 - 0.0022 17.4 0.2 2.4 7.5 0.0 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 EPS27187.1 - 0.0025 17.2 0.2 2.8 7.2 0.0 3.1 4 0 0 4 4 4 1 AAA domain Arch_ATPase PF01637.13 EPS27187.1 - 0.0027 17.4 0.0 0.77 9.4 0.0 2.7 2 0 0 2 2 2 1 Archaeal ATPase AAA_29 PF13555.1 EPS27187.1 - 0.0038 16.7 0.1 4.3 6.9 0.1 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EPS27187.1 - 0.0055 17.0 0.1 3.2 8.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EPS27187.1 - 0.014 15.0 0.0 1.1 9.0 0.0 2.9 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EPS27187.1 - 0.016 14.4 0.2 1.7 7.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EPS27187.1 - 0.03 13.4 0.6 6 5.9 0.0 3.3 3 0 0 3 3 3 0 Zeta toxin AAA_18 PF13238.1 EPS27187.1 - 0.035 14.4 1.6 6.6 7.0 0.1 2.9 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.20 EPS27187.1 - 0.038 13.4 0.4 0.51 9.7 0.1 2.4 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.17 EPS27187.1 - 0.052 12.3 0.7 3.4 6.4 0.0 3.2 2 1 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.1 EPS27187.1 - 0.053 13.0 0.4 4.5 6.8 0.0 2.6 2 1 0 2 2 2 0 AAA domain NACHT PF05729.7 EPS27187.1 - 0.059 13.0 0.7 7.6 6.1 0.0 2.7 2 1 0 2 2 2 0 NACHT domain AAA_17 PF13207.1 EPS27187.1 - 0.067 14.0 2.5 11 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 EPS27187.1 - 0.077 12.8 0.0 1.8 8.3 0.0 2.7 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_11 PF13086.1 EPS27187.1 - 0.082 12.4 0.0 0.47 9.9 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EPS27187.1 - 0.085 12.7 0.2 0.95 9.3 0.0 2.7 3 0 0 3 3 3 0 AAA domain Viral_helicase1 PF01443.13 EPS27187.1 - 0.092 12.2 0.1 15 5.0 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.18 EPS27187.1 - 0.11 12.4 0.0 14 5.6 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 EPS27187.1 - 0.29 10.9 1.9 8.8 6.1 0.0 2.7 3 0 0 3 3 2 0 Dynamin family AMP-binding PF00501.23 EPS27188.1 - 0 1901.0 0.0 2.4e-84 283.1 0.0 7.3 7 0 0 7 7 7 7 AMP-binding enzyme Condensation PF00668.15 EPS27188.1 - 1.5e-267 884.2 0.0 7.2e-40 136.7 0.0 8.4 8 0 0 8 8 8 8 Condensation domain PP-binding PF00550.20 EPS27188.1 - 6.1e-71 234.6 2.8 3.8e-10 39.8 0.1 8.1 7 0 0 7 7 7 7 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EPS27188.1 - 3.4e-35 120.8 2.1 7.4e-06 26.8 0.0 8.1 7 0 0 7 7 7 7 AMP-binding enzyme C-terminal domain RNA_pol_I_A49 PF06870.7 EPS27188.1 - 0.24 9.9 0.2 2.6 6.5 0.0 2.1 2 0 0 2 2 2 0 A49-like RNA polymerase I associated factor Abhydrolase_6 PF12697.2 EPS27189.1 - 8.3e-24 84.7 2.6 1e-23 84.4 1.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPS27189.1 - 1.7e-08 34.2 0.3 2.6e-08 33.7 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EPS27189.1 - 3.1e-08 34.1 0.1 4.8e-08 33.4 0.1 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.15 EPS27189.1 - 1e-07 31.7 0.0 1.3e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EPS27189.1 - 0.0013 18.5 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Ser_hydrolase PF06821.8 EPS27189.1 - 0.0027 17.3 0.2 0.006 16.1 0.1 1.5 1 0 0 1 1 1 1 Serine hydrolase PGAP1 PF07819.8 EPS27189.1 - 0.02 14.4 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Pyr_redox_2 PF07992.9 EPS27190.1 - 8.2e-21 74.8 0.0 1.1e-20 74.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPS27190.1 - 7.6e-07 29.0 0.7 0.0064 16.2 0.5 2.4 1 1 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.19 EPS27190.1 - 6.4e-06 25.3 0.5 8e-05 21.7 0.0 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPS27190.1 - 1.2e-05 24.4 0.4 2.1e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EPS27190.1 - 6.8e-05 21.5 0.1 0.00079 18.0 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 EPS27190.1 - 8.1e-05 22.5 0.0 8.1e-05 22.5 0.0 2.4 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EPS27190.1 - 0.00014 20.8 0.1 0.02 13.7 0.1 2.3 1 1 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EPS27190.1 - 0.00047 20.2 0.1 0.024 14.7 0.1 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EPS27190.1 - 0.0041 16.2 0.0 0.0065 15.5 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EPS27190.1 - 0.011 14.8 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 EPS27190.1 - 0.037 13.1 0.0 0.069 12.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family DIOX_N PF14226.1 EPS27191.1 - 1.1e-16 61.3 0.1 1.4e-15 57.8 0.0 2.5 2 1 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EPS27191.1 - 3.6e-14 52.8 0.0 6.9e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ketoacyl-synt PF00109.21 EPS27192.1 - 8.7e-20 71.2 0.1 1.8e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 EPS27192.1 - 2.7e-16 60.1 0.0 5e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ketoacyl-synt_C PF02801.17 EPS27192.1 - 1.8e-10 40.6 0.2 3.5e-09 36.5 0.0 2.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EPS27192.1 - 0.014 14.4 0.0 0.026 13.5 0.0 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain HLH PF00010.21 EPS27193.1 - 2.5e-10 39.8 0.7 9.8e-10 37.9 0.0 2.1 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Acyl_transf_1 PF00698.16 EPS27194.1 - 2.8e-54 184.6 0.0 1.6e-53 182.1 0.0 2.1 2 0 0 2 2 2 1 Acyl transferase domain DUF1729 PF08354.5 EPS27194.1 - 2.8e-24 84.6 0.0 5.8e-24 83.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydratas PF01575.14 EPS27194.1 - 4.8e-23 80.8 0.0 9.4e-23 79.9 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EPS27194.1 - 9.2e-10 38.4 0.0 6.2e-09 35.7 0.0 2.3 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase NMO PF03060.10 EPS27194.1 - 0.074 12.1 0.0 0.73 8.9 0.0 2.2 2 0 0 2 2 2 0 Nitronate monooxygenase FA_desaturase PF00487.19 EPS27195.1 - 2e-15 56.9 19.6 3.7e-15 56.0 13.6 1.4 1 0 0 1 1 1 1 Fatty acid desaturase FA_hydroxylase PF04116.8 EPS27196.1 - 7.5e-17 61.7 16.6 7.5e-17 61.7 11.5 1.9 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily HsbA PF12296.3 EPS27197.1 - 1.2e-19 70.3 0.0 8.3e-19 67.6 0.0 1.9 2 0 0 2 2 2 1 Hydrophobic surface binding protein A DUF1488 PF07369.6 EPS27197.1 - 0.067 13.0 0.3 1.1 9.1 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1488) KR PF08659.5 EPS27198.1 - 2.7e-57 193.3 1.6 8.4e-57 191.7 0.8 2.1 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 EPS27198.1 - 2.4e-56 191.4 0.1 4.3e-56 190.5 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EPS27198.1 - 3.7e-52 177.3 0.0 7.1e-52 176.3 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.21 EPS27198.1 - 9.5e-47 159.5 0.0 7.2e-46 156.7 0.0 2.3 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short PF00106.20 EPS27198.1 - 1.3e-44 152.0 2.1 2.2e-44 151.3 0.5 2.2 3 0 0 3 3 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EPS27198.1 - 1.7e-29 102.0 0.1 4.3e-29 100.7 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EPS27198.1 - 5.4e-18 64.7 0.0 1.8e-17 63.1 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EPS27198.1 - 3.4e-17 62.7 0.0 1.2e-16 61.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EPS27198.1 - 1.8e-12 48.2 0.0 1.1e-11 45.6 0.0 2.5 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 EPS27198.1 - 1.2e-10 41.3 0.0 3.1e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS27198.1 - 3.8e-10 40.3 0.0 1.1e-09 38.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPS27198.1 - 9.5e-09 35.0 0.0 2.4e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPS27198.1 - 3.1e-08 33.9 0.0 8.2e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 EPS27198.1 - 0.00016 21.3 0.1 0.00039 20.1 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 EPS27198.1 - 0.00048 20.3 0.0 0.0031 17.7 0.0 2.5 2 0 0 2 2 2 1 Phosphopantetheine attachment site DUF938 PF06080.7 EPS27198.1 - 0.012 15.1 0.0 0.041 13.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF938) 3Beta_HSD PF01073.14 EPS27198.1 - 0.017 13.8 0.1 0.031 12.9 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_26 PF13659.1 EPS27198.1 - 0.052 13.5 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Gas_vesicle_C PF01304.12 EPS27198.1 - 0.13 11.9 0.0 0.45 10.1 0.0 2.0 1 0 0 1 1 1 0 Gas vesicles protein GVPc repeated domain Polysacc_synt_2 PF02719.10 EPS27198.1 - 0.17 10.7 0.0 0.29 9.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Pyr_redox_3 PF13738.1 EPS27199.1 - 9.3e-16 58.4 0.1 2.5e-14 53.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EPS27199.1 - 5.1e-10 38.8 0.0 3.9e-07 29.2 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EPS27199.1 - 6.7e-10 37.7 0.0 3.2e-09 35.5 0.0 1.9 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like THF_DHG_CYH_C PF02882.14 EPS27199.1 - 0.078 12.0 0.3 6.7 5.7 0.0 2.7 2 1 1 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Pyr_redox_2 PF07992.9 EPS27199.1 - 0.14 12.0 0.0 3.3 7.5 0.0 2.4 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Hemerythrin PF01814.18 EPS27200.1 - 0.013 15.7 0.1 0.11 12.6 0.1 2.1 1 1 0 1 1 1 0 Hemerythrin HHE cation binding domain Mus7 PF09462.5 EPS27200.1 - 0.073 11.9 0.0 0.079 11.7 0.0 1.1 1 0 0 1 1 1 0 Mus7/MMS22 family Methyltransf_23 PF13489.1 EPS27201.1 - 3.3e-20 72.4 0.0 5.8e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPS27201.1 - 4.2e-12 45.9 0.0 6e-11 42.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPS27201.1 - 2.4e-10 40.7 0.0 5.4e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS27201.1 - 1.5e-08 35.1 0.0 2.6e-07 31.2 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPS27201.1 - 8.2e-08 32.6 0.0 9.2e-07 29.2 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPS27201.1 - 2.1e-05 24.8 0.0 4.5e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPS27201.1 - 0.0017 18.4 0.0 0.0054 16.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EPS27201.1 - 0.0036 17.3 0.0 0.0053 16.7 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.8 EPS27201.1 - 0.0048 16.0 0.0 0.0076 15.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EPS27201.1 - 0.01 14.8 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_16 PF10294.4 EPS27201.1 - 0.036 13.5 0.0 0.059 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.9 EPS27201.1 - 0.062 12.6 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.13 EPS27201.1 - 0.12 11.4 0.0 0.52 9.3 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family GPI-anchored PF10342.4 EPS27202.1 - 4.7e-19 68.6 4.0 4.7e-19 68.6 2.8 2.3 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Glyco_hydro_81 PF03639.8 EPS27202.1 - 0.038 12.0 0.5 0.043 11.8 0.3 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 81 Peptidase_M28 PF04389.12 EPS27203.1 - 5.5e-33 114.2 0.0 9.4e-33 113.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EPS27203.1 - 2.2e-16 59.3 0.8 6.8e-16 57.8 0.5 1.9 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.23 EPS27203.1 - 0.00012 21.6 0.0 0.00019 20.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.10 EPS27203.1 - 0.0081 15.4 0.2 0.019 14.2 0.0 1.6 2 0 0 2 2 2 1 Nicastrin GRP PF07172.6 EPS27204.1 - 0.13 12.7 4.8 0.14 12.6 3.3 1.2 1 0 0 1 1 1 0 Glycine rich protein family Beta-lactamase PF00144.19 EPS27204.1 - 3 6.7 6.2 3.2 6.6 4.3 1.1 1 0 0 1 1 1 0 Beta-lactamase DUF2877 PF11392.3 EPS27205.1 - 0.07 13.3 0.8 0.18 12.0 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2877) BLVR PF06375.6 EPS27205.1 - 0.18 11.6 23.8 0.37 10.6 3.2 2.2 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) Macoilin PF09726.4 EPS27205.1 - 1.8 6.7 21.3 2.1 6.5 14.8 1.0 1 0 0 1 1 1 0 Transmembrane protein AAA PF00004.24 EPS27206.1 - 2.5e-16 60.0 0.0 5.5e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EPS27206.1 - 9.7e-06 25.2 0.3 4.1e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 EPS27206.1 - 0.00011 22.2 0.3 0.0017 18.5 0.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EPS27206.1 - 0.0012 18.5 0.0 0.0032 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EPS27206.1 - 0.0013 18.7 0.0 0.0044 16.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EPS27206.1 - 0.0031 17.5 0.2 0.011 15.7 0.1 1.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_30 PF13604.1 EPS27206.1 - 0.0051 16.4 0.3 0.039 13.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EPS27206.1 - 0.017 15.9 0.2 0.078 13.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 EPS27206.1 - 0.017 14.6 0.0 0.037 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EPS27206.1 - 0.025 14.4 0.1 0.08 12.8 0.1 2.1 1 1 0 1 1 1 0 AAA domain Zot PF05707.7 EPS27206.1 - 0.053 12.9 0.4 2.4 7.5 0.0 2.3 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) Mg_chelatase PF01078.16 EPS27206.1 - 0.074 12.2 0.8 0.38 9.8 0.1 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Torsin PF06309.6 EPS27206.1 - 0.086 12.7 0.3 0.38 10.6 0.0 2.2 2 0 0 2 2 2 0 Torsin Ldh_1_C PF02866.13 EPS27207.1 - 8.8e-45 152.5 0.1 1.4e-44 151.8 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 EPS27207.1 - 7.4e-43 145.7 0.0 2.1e-42 144.3 0.0 1.8 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EPS27207.1 - 0.00086 18.0 0.0 0.0012 17.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EPS27207.1 - 0.0031 17.8 0.3 0.073 13.3 0.0 2.8 2 1 1 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 EPS27207.1 - 0.033 13.2 0.0 0.39 9.7 0.0 2.6 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain V-SNARE_C PF12352.3 EPS27208.1 - 5.7e-13 48.7 0.2 1.4e-12 47.4 0.1 1.7 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EPS27208.1 - 0.00043 19.9 0.0 0.0012 18.5 0.0 1.7 1 0 0 1 1 1 1 Sec20 BAR_2 PF10455.4 EPS27208.1 - 0.016 14.1 0.0 0.02 13.8 0.0 1.3 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking CHDCT2 PF08074.6 EPS27208.1 - 0.027 14.1 0.2 4.3 7.0 0.1 2.1 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain She9_MDM33 PF05546.6 EPS27208.1 - 0.037 13.5 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 She9 / Mdm33 family TPR_MLP1_2 PF07926.7 EPS27208.1 - 0.038 13.7 1.0 0.088 12.5 0.7 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF1785 PF08699.5 EPS27208.1 - 0.13 11.6 0.0 0.3 10.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1785) Vps5 PF09325.5 EPS27208.1 - 0.2 10.8 2.6 0.17 11.1 0.7 1.6 2 0 0 2 2 2 0 Vps5 C terminal like DUF4407 PF14362.1 EPS27208.1 - 1.3 7.8 4.2 3.6 6.4 2.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) 2-oxoacid_dh PF00198.18 EPS27210.1 - 2.8e-74 249.2 0.1 3.6e-74 248.9 0.1 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EPS27210.1 - 5.2e-17 61.2 0.6 1.8e-16 59.5 0.4 2.0 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EPS27210.1 - 2.6e-12 46.1 0.8 6.8e-12 44.8 0.5 1.8 1 0 0 1 1 1 1 e3 binding domain Sec7 PF01369.15 EPS27211.1 - 4.1e-66 222.2 1.6 1.4e-65 220.5 1.1 2.0 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EPS27211.1 - 7.5e-54 181.6 4.9 7.5e-54 181.6 3.4 3.0 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EPS27211.1 - 3.4e-31 106.6 2.1 4.5e-30 103.0 0.0 4.0 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) NAD_binding_7 PF13241.1 EPS27212.1 - 2.8e-33 114.2 0.0 4e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EPS27212.1 - 9.5e-28 95.3 0.0 1.6e-27 94.5 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EPS27212.1 - 5.3e-16 57.2 0.1 8.2e-16 56.6 0.1 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Pribosyltran_N PF13793.1 EPS27213.1 - 5.6e-43 145.3 0.0 4.8e-42 142.3 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EPS27213.1 - 6.7e-33 113.9 0.2 1e-27 97.0 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EPS27213.1 - 3e-05 23.7 0.2 0.0071 16.0 0.0 2.8 3 0 0 3 3 3 2 Phosphoribosyl transferase domain SpoVAD PF07451.6 EPS27213.1 - 0.082 11.3 0.0 0.14 10.6 0.0 1.3 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) Prok-RING_2 PF14445.1 EPS27215.1 - 0.21 11.5 9.1 0.35 10.8 6.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 2 zf-B_box PF00643.19 EPS27215.1 - 0.47 10.3 12.7 0.14 12.0 6.4 1.8 1 1 1 2 2 2 0 B-box zinc finger Zn_Tnp_IS91 PF14319.1 EPS27215.1 - 5.6 6.5 10.0 6.4 6.3 6.9 1.3 1 0 0 1 1 1 0 Transposase zinc-binding domain PLDc PF00614.17 EPS27217.1 - 9.7e-13 47.4 3.8 2.2e-06 27.2 0.1 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EPS27217.1 - 4.5e-12 45.8 0.2 4.5e-06 26.4 0.2 3.4 2 1 0 2 2 2 2 PLD-like domain RFX_DNA_binding PF02257.10 EPS27218.1 - 1.5e-29 101.9 0.2 3.3e-29 100.8 0.2 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain LigB PF02900.13 EPS27219.1 - 5.5e-23 81.3 0.0 6.9e-23 80.9 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Fungal_trans PF04082.13 EPS27220.1 - 7.3e-17 61.0 2.5 1.1e-16 60.5 1.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS27220.1 - 2.6e-06 27.2 12.6 4.6e-06 26.4 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3425 PF11905.3 EPS27221.1 - 1.3e-38 131.9 4.2 1.3e-38 131.9 2.9 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) Herpes_capsid PF06112.6 EPS27221.1 - 0.16 11.9 7.0 0.35 10.8 4.9 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Glyco_hydro_43 PF04616.9 EPS27222.1 - 5.3e-68 229.1 1.4 7.1e-68 228.7 0.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 MFS_1 PF07690.11 EPS27223.1 - 4.3e-23 81.5 56.6 2e-13 49.8 17.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ACOX PF01756.14 EPS27224.1 - 9.5e-39 132.7 0.0 3e-38 131.0 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 EPS27224.1 - 2e-27 95.9 3.0 4.2e-27 94.9 2.1 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 EPS27224.1 - 8e-13 47.6 0.9 1.8e-12 46.5 0.2 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EPS27224.1 - 2.2e-06 27.8 0.3 0.019 15.1 0.0 2.8 3 0 0 3 3 3 2 Acyl-CoA dehydrogenase, C-terminal domain Sugar_tr PF00083.19 EPS27225.1 - 4.9e-96 322.0 30.9 5.7e-96 321.8 21.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS27225.1 - 2.3e-25 89.0 41.1 9.7e-23 80.4 15.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EPS27225.1 - 9e-05 20.8 1.2 9e-05 20.8 0.9 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) ABC2_membrane_5 PF13346.1 EPS27225.1 - 0.0063 15.8 10.0 0.0063 15.8 6.9 3.2 3 0 0 3 3 3 1 ABC-2 family transporter protein Sugar_tr PF00083.19 EPS27226.1 - 6e-110 367.8 25.8 7e-110 367.6 17.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS27226.1 - 6e-22 77.8 24.1 3e-14 52.5 4.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EPS27226.1 - 0.0021 16.1 5.9 0.34 8.9 0.1 2.7 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family DUF1228 PF06779.9 EPS27226.1 - 0.16 11.9 6.8 0.098 12.6 0.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) MFS_1 PF07690.11 EPS27227.1 - 8.8e-45 152.9 42.8 1.7e-44 152.0 27.4 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPS27227.1 - 1.7e-10 39.7 16.3 2.6e-10 39.1 11.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EPS27227.1 - 4.3e-08 32.1 9.7 4.3e-08 32.1 6.7 3.8 4 1 0 4 4 4 2 Sugar (and other) transporter SIT PF15330.1 EPS27227.1 - 0.039 14.1 0.4 0.51 10.4 0.0 2.7 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Sugar_tr PF00083.19 EPS27228.1 - 2.5e-87 293.3 21.8 2.9e-87 293.1 15.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS27228.1 - 6.1e-26 90.9 38.0 8.5e-25 87.2 21.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EPS27228.1 - 2.4e-05 22.5 2.6 0.0027 15.8 0.0 2.3 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family UDPG_MGDP_dh_N PF03721.9 EPS27229.1 - 4.3e-50 169.6 0.1 4e-48 163.2 0.1 2.3 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 EPS27229.1 - 4.9e-30 103.5 0.0 9.8e-30 102.6 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 EPS27229.1 - 1.3e-22 79.9 0.0 7e-17 61.5 0.0 3.4 3 0 0 3 3 3 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_Gly3P_dh_N PF01210.18 EPS27229.1 - 0.00035 20.3 0.2 2.7 7.7 0.0 3.8 3 1 0 3 3 3 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 EPS27229.1 - 0.0034 16.8 0.0 0.0085 15.5 0.0 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.10 EPS27229.1 - 0.0038 17.0 0.1 0.34 10.7 0.0 2.8 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Saccharop_dh PF03435.13 EPS27229.1 - 0.0045 16.0 0.0 0.0087 15.0 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase DAO PF01266.19 EPS27229.1 - 0.011 14.6 0.0 0.37 9.6 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 EPS27229.1 - 0.032 13.9 0.0 0.072 12.7 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EPS27229.1 - 0.034 14.1 0.1 0.26 11.3 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain TPT PF03151.11 EPS27231.1 - 5.1e-19 68.4 12.6 5.1e-19 68.4 8.7 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EPS27231.1 - 0.0068 15.3 28.1 0.012 14.5 19.5 1.3 1 1 0 1 1 1 1 UAA transporter family KdpC PF02669.10 EPS27231.1 - 6.5 6.4 7.4 8.5 6.0 0.5 2.6 3 0 0 3 3 3 0 K+-transporting ATPase, c chain EamA PF00892.15 EPS27231.1 - 6.8 6.7 43.8 0.17 11.8 10.9 3.1 2 1 1 3 3 3 0 EamA-like transporter family DUF1480 PF07351.8 EPS27233.1 - 0.075 13.0 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1480) Herpes_UL46 PF03387.9 EPS27236.1 - 0.098 10.8 0.0 0.11 10.6 0.0 1.0 1 0 0 1 1 1 0 Herpesvirus UL46 protein DNA_pack_N PF02500.10 EPS27237.1 - 0.0045 16.5 3.0 48 3.3 0.0 5.7 2 1 5 7 7 7 0 Probable DNA packing protein, N-terminus DUF2730 PF10805.3 EPS27237.1 - 0.032 13.9 2.8 1.7 8.4 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) PP2C_C PF07830.8 EPS27237.1 - 0.13 12.3 4.1 1.2e+02 2.8 0.0 5.2 5 0 0 5 5 5 0 Protein serine/threonine phosphatase 2C, C-terminal domain Lipid_DES PF08557.5 EPS27237.1 - 0.64 9.3 1.9 17 4.7 0.0 3.3 4 0 0 4 4 4 0 Sphingolipid Delta4-desaturase (DES) Het-C PF07217.6 EPS27237.1 - 0.81 7.8 5.6 2.6 6.1 0.0 2.8 2 1 0 2 2 2 0 Heterokaryon incompatibility protein Het-C LUC7 PF03194.10 EPS27237.1 - 1.2 8.6 2.9 48 3.3 0.6 4.0 5 1 0 5 5 5 0 LUC7 N_terminus TFIIA PF03153.8 EPS27237.1 - 2.5 7.9 7.4 3.9 7.2 5.1 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EF-hand_7 PF13499.1 EPS27239.1 - 7e-14 51.7 0.2 6.6e-10 38.9 0.1 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EPS27239.1 - 1.3e-10 40.2 0.7 0.0085 15.8 0.0 3.9 4 0 0 4 4 4 2 EF-hand domain EF-hand_9 PF14658.1 EPS27239.1 - 9.7e-09 35.0 0.0 0.0014 18.5 0.0 2.4 2 1 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EPS27239.1 - 2.1e-08 32.8 1.2 0.013 14.7 0.0 3.9 4 1 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 EPS27239.1 - 6.5e-07 28.8 0.6 0.00076 19.0 0.1 3.5 2 1 1 3 3 3 1 EF-hand domain pair DUF3216 PF11505.3 EPS27239.1 - 0.028 14.2 0.0 0.086 12.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3216) UPF0154 PF03672.8 EPS27239.1 - 0.058 13.0 0.0 0.12 12.0 0.0 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) EF-hand_5 PF13202.1 EPS27239.1 - 1.4 8.4 7.0 2.2 7.7 0.7 3.0 3 0 0 3 3 3 0 EF hand Fungal_trans PF04082.13 EPS27241.1 - 7e-63 211.9 0.0 9.6e-63 211.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 EPS27241.1 - 0.0011 19.1 15.1 0.0012 19.0 1.6 3.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EPS27241.1 - 0.0015 18.7 2.9 0.0015 18.7 2.0 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EPS27241.1 - 0.0021 18.2 8.5 0.02 15.1 2.7 2.7 2 0 0 2 2 2 1 Zinc-finger double domain PHO4 PF01384.15 EPS27243.1 - 1.5e-108 362.3 12.0 1.8e-108 362.0 8.3 1.1 1 0 0 1 1 1 1 Phosphate transporter family Glycophorin_A PF01102.13 EPS27243.1 - 0.0003 20.5 0.0 0.0011 18.6 0.0 1.9 1 0 0 1 1 1 1 Glycophorin A Xpo1 PF08389.7 EPS27244.1 - 1.8e-26 92.8 0.1 8.9e-25 87.3 0.0 3.6 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 EPS27244.1 - 8.5e-05 22.4 0.0 0.00045 20.0 0.0 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 EPS27244.1 - 0.016 15.4 0.0 0.3 11.3 0.0 3.0 2 0 0 2 2 2 0 HEAT repeats HEAT PF02985.17 EPS27244.1 - 0.078 13.0 1.4 1.5 9.1 0.0 3.8 4 0 0 4 4 4 0 HEAT repeat Pardaxin PF07425.6 EPS27244.1 - 1.7 8.1 3.7 1.9 7.9 0.1 2.6 2 0 0 2 2 2 0 Pardaxin LSM PF01423.17 EPS27245.1 - 6.2e-15 54.4 0.0 7.3e-15 54.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain 5-FTHF_cyc-lig PF01812.15 EPS27246.1 - 2.5e-37 128.4 0.0 2.9e-37 128.2 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Rot1 PF10681.4 EPS27247.1 - 2.7e-87 291.5 0.0 3.1e-87 291.3 0.0 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal YqeY PF09424.5 EPS27248.1 - 1.2e-22 80.3 6.1 1.3e-22 80.1 4.2 1.0 1 0 0 1 1 1 1 Yqey-like protein PRA-PH PF01503.12 EPS27248.1 - 0.076 13.2 2.2 0.15 12.3 1.5 1.7 1 1 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase CM_2 PF01817.16 EPS27248.1 - 0.22 11.6 2.7 0.5 10.5 1.8 1.6 1 1 0 1 1 1 0 Chorismate mutase type II KfrA_N PF11740.3 EPS27248.1 - 0.82 10.1 8.2 0.96 9.9 4.5 2.0 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term Nucleoporin_C PF03177.9 EPS27249.1 - 4.3e-140 468.0 5.5 6e-140 467.5 3.8 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EPS27249.1 - 6.1e-87 292.0 0.1 8.7e-87 291.5 0.1 1.2 1 0 0 1 1 1 1 Nup133 N terminal like ADSL_C PF10397.4 EPS27249.1 - 0.045 13.7 0.2 0.55 10.2 0.1 2.7 2 0 0 2 2 2 0 Adenylosuccinate lyase C-terminus TauD PF02668.11 EPS27250.1 - 2.7e-48 164.9 0.1 3.3e-48 164.6 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF2781 PF10914.3 EPS27252.1 - 1.1e-37 129.0 11.5 1.3e-37 128.8 8.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) Asp_protease PF09668.5 EPS27253.1 - 5.6e-60 200.3 0.1 8.8e-60 199.7 0.1 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EPS27253.1 - 1e-10 41.9 0.0 2.5e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease UBA PF00627.26 EPS27253.1 - 1.3e-06 28.0 0.0 3.5e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain ubiquitin PF00240.18 EPS27253.1 - 2.2e-06 26.9 0.0 4e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family RVP_2 PF08284.6 EPS27253.1 - 2.3e-06 27.5 0.0 4.2e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EPS27253.1 - 1.2e-05 24.9 0.0 2.8e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 EPS27253.1 - 0.0014 18.5 0.0 0.0054 16.6 0.0 2.1 1 1 0 1 1 1 1 Retroviral aspartyl protease RuvA_C PF07499.8 EPS27253.1 - 0.013 15.6 0.9 0.14 12.3 0.0 2.7 3 0 0 3 3 3 0 RuvA, C-terminal domain Rad60-SLD PF11976.3 EPS27253.1 - 0.019 14.6 0.0 0.039 13.6 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like UBA_4 PF14555.1 EPS27253.1 - 0.022 14.2 0.1 0.053 13.0 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain PsbH PF00737.15 EPS27253.1 - 0.096 12.2 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein zf-RING_2 PF13639.1 EPS27255.1 - 3.8e-14 52.2 3.5 6.7e-14 51.4 2.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EPS27255.1 - 4.4e-08 32.6 1.5 7.5e-08 31.9 1.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPS27255.1 - 1.3e-07 31.4 2.1 2.3e-07 30.6 1.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EPS27255.1 - 5.6e-07 29.5 4.1 1.5e-06 28.2 2.8 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EPS27255.1 - 6.1e-06 25.8 1.4 1.1e-05 25.1 1.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EPS27255.1 - 0.00025 20.6 1.4 0.00042 19.9 1.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 EPS27255.1 - 0.0018 18.2 2.0 0.0033 17.3 1.4 1.4 1 0 0 1 1 1 1 RING-like domain Vps39_2 PF10367.4 EPS27255.1 - 0.0052 16.9 0.4 0.0087 16.2 0.2 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-Apc11 PF12861.2 EPS27255.1 - 0.012 15.4 2.7 0.038 13.8 1.9 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EPS27255.1 - 0.013 15.5 2.0 0.036 14.1 1.4 1.8 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 EPS27255.1 - 0.013 15.4 2.0 0.032 14.1 1.4 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 EPS27255.1 - 0.05 13.3 1.7 0.11 12.2 1.2 1.6 1 0 0 1 1 1 0 RING-type zinc-finger DUF4448 PF14610.1 EPS27255.1 - 0.087 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) PHD PF00628.24 EPS27255.1 - 0.088 12.5 2.2 0.15 11.7 1.5 1.4 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.1 EPS27255.1 - 0.12 12.1 0.5 0.22 11.2 0.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-C3HC4_4 PF15227.1 EPS27255.1 - 0.21 11.4 1.2 0.71 9.7 0.9 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF3754 PF12576.3 EPS27257.1 - 1 8.9 5.6 2 8.0 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3754) Peptidase_M3 PF01432.15 EPS27259.1 - 9.9e-162 539.1 0.0 1.4e-161 538.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 SUV3_C PF12513.3 EPS27259.1 - 0.013 14.9 0.0 0.045 13.2 0.0 1.9 1 0 0 1 1 1 0 Mitochondrial degradasome RNA helicase subunit C terminal AMP-binding PF00501.23 EPS27260.1 - 2.8e-74 249.9 0.0 4e-74 249.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EPS27260.1 - 3e-57 193.4 0.0 4.5e-57 192.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EPS27260.1 - 6.8e-15 55.1 0.0 1.6e-14 53.9 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 EPS27260.1 - 7.9e-14 52.3 1.1 2e-13 51.0 0.2 2.2 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.20 EPS27260.1 - 6.7e-09 35.8 0.1 1.3e-08 34.9 0.1 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 EPS27260.1 - 9.9e-09 34.2 0.0 3.4e-08 32.5 0.0 1.9 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EPS27260.1 - 0.0019 18.4 0.0 0.0043 17.3 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 EPS27260.1 - 0.021 13.7 0.0 0.045 12.6 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.20 EPS27260.1 - 0.13 12.1 0.1 0.59 10.0 0.0 2.2 2 0 0 2 2 2 0 short chain dehydrogenase Aminotran_1_2 PF00155.16 EPS27261.1 - 1e-30 106.9 0.0 1.2e-30 106.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EPS27261.1 - 0.00078 17.8 0.0 0.0013 17.0 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EPS27261.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase FA_desaturase PF00487.19 EPS27262.1 - 1.6e-20 73.6 13.9 3.3e-20 72.6 9.6 1.5 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EPS27262.1 - 6.1e-18 64.3 0.1 1.6e-17 63.0 0.0 1.7 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DNA_pol_B_palm PF14792.1 EPS27263.1 - 0.063 13.3 0.0 0.082 12.9 0.0 1.3 1 1 0 1 1 1 0 DNA polymerase beta palm Xan_ur_permease PF00860.15 EPS27264.1 - 3.5e-65 219.9 36.6 3.6e-64 216.6 25.4 2.0 1 1 0 1 1 1 1 Permease family MOSC PF03473.12 EPS27265.1 - 6.2e-15 54.8 0.0 1.4e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 EPS27265.1 - 4.9e-10 39.1 0.0 8.6e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain DUF1705 PF08019.7 EPS27265.1 - 0.19 11.2 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1705) Rad51 PF08423.6 EPS27266.1 - 1.8e-09 36.9 0.0 2.4e-08 33.2 0.0 2.1 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EPS27266.1 - 7.5e-08 31.9 0.1 9.3e-07 28.4 0.1 2.4 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 EPS27266.1 - 3.9e-07 29.4 0.0 1.2e-06 27.8 0.0 1.7 2 0 0 2 2 2 1 KaiC RecA PF00154.16 EPS27266.1 - 4.4e-07 29.2 0.1 1e-06 28.0 0.0 1.7 1 1 0 1 1 1 1 recA bacterial DNA recombination protein IstB_IS21 PF01695.12 EPS27266.1 - 2.2e-05 23.9 0.0 4.1e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_10 PF12846.2 EPS27266.1 - 4.3e-05 23.1 0.1 9e-05 22.0 0.0 1.5 2 0 0 2 2 2 1 AAA-like domain AAA_24 PF13479.1 EPS27266.1 - 0.00048 19.7 0.0 0.0025 17.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EPS27266.1 - 0.0017 18.5 0.0 0.004 17.3 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EPS27266.1 - 0.0037 17.1 0.1 0.029 14.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_31 PF13614.1 EPS27266.1 - 0.0046 16.8 0.0 0.027 14.4 0.0 2.0 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.1 EPS27266.1 - 0.0083 15.8 0.3 0.028 14.1 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 EPS27266.1 - 0.013 15.6 0.0 0.028 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EPS27266.1 - 0.014 16.1 0.4 0.1 13.3 0.0 2.6 2 1 0 2 2 1 0 AAA domain AAA_16 PF13191.1 EPS27266.1 - 0.034 14.1 0.0 0.08 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Zot PF05707.7 EPS27266.1 - 0.042 13.3 0.0 0.065 12.6 0.0 1.3 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) PhoH PF02562.11 EPS27266.1 - 0.12 11.5 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein MobB PF03205.9 EPS27266.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Proteasome PF00227.21 EPS27269.1 - 3.7e-56 189.4 0.0 1.2e-31 109.4 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 EPS27269.1 - 1.7e-11 43.2 0.3 4.1e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Methyltransf_2 PF00891.13 EPS27269.1 - 0.13 11.4 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase RINGv PF12906.2 EPS27270.1 - 1e-09 38.2 3.2 4.3e-09 36.2 0.7 2.3 2 0 0 2 2 2 1 RING-variant domain zf-RanBP PF00641.13 EPS27270.1 - 0.061 12.4 0.1 0.12 11.4 0.1 1.4 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others DUF1206 PF06724.6 EPS27270.1 - 0.078 12.7 0.9 0.078 12.7 0.6 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) zf-RING_2 PF13639.1 EPS27270.1 - 0.087 12.6 9.1 1 9.2 6.3 2.2 1 1 0 1 1 1 0 Ring finger domain PHD PF00628.24 EPS27270.1 - 4.2 7.1 6.1 2 8.1 2.5 1.7 2 0 0 2 2 2 0 PHD-finger Amidohydro_2 PF04909.9 EPS27272.1 - 4.1e-44 151.1 0.2 5e-44 150.8 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase Acid_PPase PF12689.2 EPS27272.1 - 0.05 13.2 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 Acid Phosphatase Sugar_tr PF00083.19 EPS27273.1 - 2.4e-85 286.7 33.0 3.1e-85 286.4 22.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS27273.1 - 1e-13 50.7 31.6 1e-13 50.7 21.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CTP_synth_N PF06418.9 EPS27274.1 - 1.2e-115 385.3 0.6 1.7e-115 384.8 0.4 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EPS27274.1 - 2.3e-51 174.0 0.0 3.5e-51 173.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EPS27274.1 - 4.7e-07 29.4 0.0 1.2e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 EPS27274.1 - 0.00011 21.6 0.0 0.00044 19.7 0.0 1.8 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain Ank_2 PF12796.2 EPS27275.1 - 5.1e-60 199.8 2.3 4.5e-18 65.3 0.0 7.3 3 2 6 9 9 9 9 Ankyrin repeats (3 copies) Ank PF00023.25 EPS27275.1 - 1.3e-41 138.4 12.6 6.5e-07 28.8 0.0 11.5 13 0 0 13 13 13 8 Ankyrin repeat Ank_4 PF13637.1 EPS27275.1 - 2.8e-32 110.4 3.5 1.1e-09 38.5 0.0 9.0 8 2 1 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPS27275.1 - 4.5e-31 103.7 6.3 0.0024 17.9 0.0 11.9 13 0 0 13 13 13 6 Ankyrin repeat Ank_5 PF13857.1 EPS27275.1 - 4.6e-28 96.6 8.4 7.9e-06 25.9 0.0 10.0 6 3 6 12 12 12 6 Ankyrin repeats (many copies) F-box-like PF12937.2 EPS27275.1 - 0.00011 21.8 0.4 0.00028 20.5 0.2 1.7 1 0 0 1 1 1 1 F-box-like Pectate_lyase_3 PF12708.2 EPS27276.1 - 7.7e-81 271.4 16.8 2.3e-65 220.9 2.5 3.1 4 0 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EPS27276.1 - 0.00025 20.4 1.2 0.046 13.2 0.1 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase DNase_NucA_NucB PF14040.1 EPS27277.1 - 0.0008 19.5 0.1 0.2 11.8 0.0 2.7 3 0 0 3 3 3 2 Deoxyribonuclease NucA/NucB F-box-like PF12937.2 EPS27278.1 - 5.5e-07 29.2 0.4 1.4e-06 27.9 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EPS27278.1 - 1.7e-06 27.5 0.4 3.2e-06 26.6 0.3 1.4 1 0 0 1 1 1 1 F-box domain Ret_tiss PF10044.4 EPS27278.1 - 0.014 15.9 0.0 0.027 14.9 0.0 1.5 1 0 0 1 1 1 0 Retinal tissue protein GATA-N PF05349.7 EPS27279.1 - 0.023 14.8 0.0 0.023 14.8 0.0 1.1 1 0 0 1 1 1 0 GATA-type transcription activator, N-terminal DUF1814 PF08843.6 EPS27282.1 - 0.033 13.9 0.1 0.045 13.5 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF1814) GFA PF04828.9 EPS27284.1 - 2.7e-21 75.2 0.0 3.5e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Pkinase PF00069.20 EPS27285.1 - 0.00017 20.8 0.0 0.00033 19.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain RRM_6 PF14259.1 EPS27286.1 - 5.8e-20 71.0 0.0 1.6e-13 50.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPS27286.1 - 6.1e-19 67.4 0.0 3.2e-14 52.2 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS27286.1 - 6.6e-11 41.8 0.0 9.4e-05 22.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Laminin_G_2 PF02210.19 EPS27286.1 - 0.043 13.8 0.0 0.31 11.0 0.0 2.1 2 0 0 2 2 2 0 Laminin G domain Laminin_G_1 PF00054.18 EPS27286.1 - 0.068 13.1 0.0 0.92 9.5 0.0 2.2 2 0 0 2 2 2 0 Laminin G domain TrkA_C PF02080.16 EPS27286.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-C domain 6PF2K PF01591.13 EPS27287.1 - 1.3e-77 259.8 0.1 1.9e-77 259.3 0.0 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EPS27287.1 - 3.2e-34 118.3 0.0 5.9e-34 117.4 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EPS27287.1 - 1.5e-05 24.9 0.0 3.1e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EPS27287.1 - 0.0017 17.6 0.0 0.0027 16.9 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 EPS27287.1 - 0.016 16.0 0.0 0.17 12.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain Vps39_2 PF10367.4 EPS27288.1 - 1e-31 109.3 0.0 3.4e-31 107.6 0.0 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 EPS27288.1 - 7.8e-29 99.8 0.0 3.5e-28 97.7 0.0 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.17 EPS27288.1 - 2.2e-17 63.3 0.0 4.2e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.15 EPS27288.1 - 9e-08 31.8 2.6 4.4e-06 26.3 0.4 3.0 3 0 0 3 3 3 1 Region in Clathrin and VPS DUF3893 PF13032.1 EPS27288.1 - 0.0074 16.4 0.1 0.016 15.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3893) TPR_1 PF00515.23 EPS27288.1 - 0.015 14.8 0.5 0.99 9.1 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat CPSF_A PF03178.10 EPS27288.1 - 0.025 13.6 0.0 6.3 5.7 0.0 2.2 2 0 0 2 2 2 0 CPSF A subunit region TPR_11 PF13414.1 EPS27288.1 - 0.053 13.1 0.8 5 6.8 0.0 3.4 2 1 1 3 3 3 0 TPR repeat TPR_12 PF13424.1 EPS27288.1 - 0.14 12.0 8.7 0.59 10.1 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Gon7 PF08738.5 EPS27289.1 - 4.2e-15 55.5 4.5 2.6e-13 49.8 3.1 2.0 1 1 0 1 1 1 1 Gon7 family DUF4611 PF15387.1 EPS27289.1 - 0.088 12.9 2.3 0.12 12.5 1.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) HbrB PF08539.6 EPS27290.1 - 1.5e-52 177.6 0.1 2.2e-52 177.0 0.0 1.2 1 0 0 1 1 1 1 HbrB-like CFEM PF05730.6 EPS27291.1 - 2.7e-05 23.8 3.7 2.7e-05 23.8 2.6 2.7 2 0 0 2 2 2 1 CFEM domain Tme5_EGF_like PF09064.5 EPS27291.1 - 0.045 13.3 3.1 0.21 11.2 2.1 2.2 1 0 0 1 1 1 0 Thrombomodulin like fifth domain, EGF-like Fungal_trans PF04082.13 EPS27292.1 - 4.4e-12 45.4 0.1 6.8e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS27292.1 - 4e-09 36.2 10.2 6.5e-09 35.5 7.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhyH PF05721.8 EPS27293.1 - 3.5e-06 27.2 0.1 7.9e-06 26.0 0.1 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 EPS27293.1 - 2.8e-05 22.7 0.0 0.49 8.8 0.1 3.0 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_5 PF13759.1 EPS27293.1 - 0.001 19.2 0.0 0.0023 18.1 0.0 1.5 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase NmrA PF05368.8 EPS27296.1 - 3.7e-19 68.9 0.0 4.5e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPS27296.1 - 2.1e-10 40.8 0.0 4e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EPS27296.1 - 0.001 19.0 0.1 0.013 15.4 0.0 2.4 2 1 0 2 2 2 1 short chain dehydrogenase Methyltransf_11 PF08241.7 EPS27296.1 - 0.0019 18.6 0.0 0.0081 16.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain TrkA_N PF02254.13 EPS27296.1 - 0.0065 16.4 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain HTH_15 PF12324.3 EPS27296.1 - 0.087 12.4 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase Methyltransf_12 PF08242.7 EPS27296.1 - 0.12 12.8 0.0 0.37 11.2 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain MFS_1 PF07690.11 EPS27298.1 - 3.4e-22 78.6 21.8 3.4e-22 78.6 15.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS27298.1 - 7.4e-10 37.9 24.3 4.7e-09 35.3 16.0 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter DUF4191 PF13829.1 EPS27298.1 - 5.4 6.0 7.5 0.33 10.0 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) Peptidase_S15 PF02129.13 EPS27299.1 - 1.5e-44 152.4 0.0 1.4e-40 139.4 0.0 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 EPS27299.1 - 8.6e-30 104.2 0.0 1.2e-29 103.7 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 EPS27299.1 - 0.0011 18.9 0.0 0.0022 17.9 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family ThiF PF00899.16 EPS27301.1 - 1.5e-13 50.7 0.0 2.6e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 ThiF family Ytp1 PF10355.4 EPS27302.1 - 1.4e-84 283.5 20.0 1.4e-84 283.5 13.9 1.9 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EPS27302.1 - 2.5e-32 110.5 1.8 2.5e-32 110.5 1.3 3.3 4 1 1 5 5 5 1 Domain of unknown function (DUF2427) DUF4051 PF13260.1 EPS27302.1 - 0.17 11.2 1.1 2.4 7.5 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) Swi5 PF07061.6 EPS27303.1 - 9.6e-33 111.8 0.4 1.1e-32 111.6 0.3 1.1 1 0 0 1 1 1 1 Swi5 Atg14 PF10186.4 EPS27303.1 - 0.0018 17.2 0.4 0.0022 16.9 0.3 1.0 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 TACC PF05010.9 EPS27303.1 - 0.0033 17.2 0.1 0.0038 17.0 0.0 1.1 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC) TSC22 PF01166.13 EPS27303.1 - 0.011 15.6 0.5 0.023 14.6 0.2 1.6 1 1 1 2 2 2 0 TSC-22/dip/bun family DUF342 PF03961.8 EPS27303.1 - 0.014 13.8 0.3 0.015 13.7 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF904 PF06005.7 EPS27303.1 - 0.021 15.1 0.8 0.027 14.7 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DivIC PF04977.10 EPS27303.1 - 0.024 14.1 3.9 0.085 12.3 2.7 1.9 1 1 0 1 1 1 0 Septum formation initiator DUF2115 PF09888.4 EPS27303.1 - 0.041 13.9 0.0 0.045 13.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) Prefoldin_2 PF01920.15 EPS27303.1 - 0.045 13.5 0.9 0.17 11.6 0.4 1.8 1 1 1 2 2 2 0 Prefoldin subunit TMF_DNA_bd PF12329.3 EPS27303.1 - 0.045 13.5 0.4 0.069 12.9 0.3 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding BicD PF09730.4 EPS27303.1 - 0.047 12.0 0.1 0.051 11.9 0.1 1.0 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D Cep57_MT_bd PF06657.8 EPS27303.1 - 0.048 13.5 0.5 0.07 13.0 0.4 1.3 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Snf7 PF03357.16 EPS27303.1 - 0.077 12.3 0.6 0.082 12.2 0.4 1.1 1 0 0 1 1 1 0 Snf7 Snapin_Pallidin PF14712.1 EPS27303.1 - 0.21 11.9 2.1 0.42 10.9 1.2 1.7 1 1 0 1 1 1 0 Snapin/Pallidin HALZ PF02183.13 EPS27303.1 - 0.37 10.5 2.4 0.69 9.6 1.4 1.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper ABC_membrane PF00664.18 EPS27304.1 - 2.5e-90 302.6 34.8 2.4e-48 164.9 8.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EPS27304.1 - 3.3e-68 228.2 0.0 8.8e-33 113.4 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EPS27304.1 - 1.7e-13 50.3 0.1 0.00082 18.6 0.0 4.0 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EPS27304.1 - 2.4e-10 40.8 0.0 0.045 13.7 0.0 4.4 3 1 0 3 3 3 3 AAA domain AAA_17 PF13207.1 EPS27304.1 - 4.5e-09 37.1 0.2 0.0035 18.1 0.0 3.9 4 0 0 4 4 3 2 AAA domain AAA_29 PF13555.1 EPS27304.1 - 7.4e-09 35.0 0.2 0.0003 20.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 EPS27304.1 - 4.2e-08 32.1 0.2 0.0017 17.0 0.0 2.6 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 EPS27304.1 - 2.3e-07 30.9 3.0 0.0012 18.9 0.0 3.4 3 1 0 3 3 3 2 AAA ATPase domain AAA PF00004.24 EPS27304.1 - 4.6e-07 30.1 0.1 4.7 7.4 0.0 4.5 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EPS27304.1 - 3.6e-06 26.2 0.1 0.095 11.8 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EPS27304.1 - 8.4e-06 25.9 0.3 0.48 10.5 0.0 4.1 4 0 0 4 4 4 2 AAA domain AAA_30 PF13604.1 EPS27304.1 - 7e-05 22.4 1.8 2.4 7.6 0.0 4.2 5 0 0 5 5 5 2 AAA domain SbcCD_C PF13558.1 EPS27304.1 - 0.00018 21.3 2.3 0.36 10.7 0.2 3.6 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 EPS27304.1 - 0.00018 20.9 2.3 0.47 9.8 0.0 3.3 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.1 EPS27304.1 - 0.00019 21.2 0.0 0.7 9.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EPS27304.1 - 0.00036 20.8 0.0 0.38 11.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EPS27304.1 - 0.001 18.7 0.5 3 7.5 0.0 3.2 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 EPS27304.1 - 0.0011 18.5 3.3 2.6 7.4 0.0 3.9 4 0 0 4 4 4 2 AAA-like domain AAA_23 PF13476.1 EPS27304.1 - 0.0012 19.2 0.2 0.51 10.6 0.0 2.8 3 0 0 3 3 2 1 AAA domain Rad17 PF03215.10 EPS27304.1 - 0.0041 15.8 0.1 0.075 11.6 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein MobB PF03205.9 EPS27304.1 - 0.007 16.0 0.3 5.9 6.6 0.0 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 EPS27304.1 - 0.0081 15.6 0.4 1.1 8.6 0.0 2.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain DUF87 PF01935.12 EPS27304.1 - 0.01 15.6 0.3 2.1 8.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_14 PF13173.1 EPS27304.1 - 0.016 15.1 0.0 4.6 7.1 0.0 3.6 4 0 0 4 4 3 0 AAA domain Zeta_toxin PF06414.7 EPS27304.1 - 0.016 14.2 0.3 4.4 6.3 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin AAA_28 PF13521.1 EPS27304.1 - 0.017 15.1 0.4 1.2 9.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EPS27304.1 - 0.021 14.9 0.1 4.6 7.4 0.0 3.1 3 0 0 3 3 2 0 RNA helicase AAA_19 PF13245.1 EPS27304.1 - 0.034 13.9 3.8 2 8.2 0.1 3.2 3 0 0 3 3 2 0 Part of AAA domain PRK PF00485.13 EPS27304.1 - 0.043 13.3 0.0 2.7 7.4 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family BTB PF00651.26 EPS27304.1 - 0.3 11.1 1.2 3.4 7.6 0.2 2.6 2 1 0 2 2 2 0 BTB/POZ domain Ribosomal_L39 PF00832.15 EPS27305.1 - 1.2e-22 79.0 9.0 1.4e-22 78.8 6.3 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Selenoprotein_S PF06936.6 EPS27305.1 - 0.1 12.1 0.7 0.12 11.9 0.5 1.1 1 0 0 1 1 1 0 Selenoprotein S (SelS) Ribosomal_L13e PF01294.13 EPS27305.1 - 0.18 11.2 2.2 0.19 11.2 1.5 1.0 1 0 0 1 1 1 0 Ribosomal protein L13e Skp1 PF01466.14 EPS27306.1 - 1e-39 134.4 2.0 1.8e-39 133.6 1.4 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EPS27306.1 - 1.1e-21 76.6 0.1 2.6e-21 75.4 0.0 1.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF4375 PF14300.1 EPS27306.1 - 0.09 12.7 0.6 0.15 12.0 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) Glyco_transf_22 PF03901.12 EPS27307.1 - 1.1e-65 222.2 16.8 1.4e-65 221.9 11.6 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family XPC-binding PF09280.6 EPS27308.1 - 9.2e-22 76.2 11.2 1.8e-21 75.3 7.7 1.5 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.26 EPS27308.1 - 8.6e-17 60.4 2.0 2.1e-09 36.9 0.1 2.5 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.18 EPS27308.1 - 4.3e-14 51.6 0.2 7.5e-14 50.8 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EPS27308.1 - 6.1e-07 29.0 0.6 1.2e-06 28.0 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 EPS27308.1 - 0.00029 20.6 0.0 0.00029 20.6 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.5 EPS27308.1 - 0.0059 16.1 0.0 2 8.1 0.0 2.4 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain DUF2407 PF10302.4 EPS27308.1 - 0.011 15.8 1.1 0.025 14.7 0.4 2.1 2 1 0 2 2 2 0 DUF2407 ubiquitin-like domain Rap1_C PF11626.3 EPS27308.1 - 0.03 14.2 0.0 2.7 7.9 0.0 2.5 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF2360 PF10152.4 EPS27308.1 - 1.1 9.4 11.2 2 8.6 2.7 2.5 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Gly-zipper_OmpA PF13436.1 EPS27308.1 - 8 6.1 20.7 0.12 12.0 4.3 2.4 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain ABC2_membrane_5 PF13346.1 EPS27309.1 - 0.18 11.0 2.8 0.27 10.5 1.9 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein eIF-6 PF01912.13 EPS27311.1 - 1.2e-83 279.1 0.9 1.5e-83 278.7 0.6 1.1 1 0 0 1 1 1 1 eIF-6 family SET PF00856.23 EPS27312.1 - 1.8e-20 73.9 0.4 1.8e-20 73.9 0.3 3.7 3 1 0 3 3 3 1 SET domain SRI PF08236.6 EPS27312.1 - 5e-16 58.4 11.9 1.2e-15 57.1 8.2 1.7 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain WW PF00397.21 EPS27312.1 - 0.00028 20.6 1.3 0.00061 19.6 0.9 1.6 1 0 0 1 1 1 1 WW domain Med26 PF08711.6 EPS27312.1 - 0.00081 18.8 0.1 0.00081 18.8 0.1 2.1 3 0 0 3 3 3 1 TFIIS helical bundle-like domain AT_hook PF02178.14 EPS27314.1 - 0.0032 16.9 1.4 0.017 14.7 1.0 2.4 1 0 0 1 1 1 1 AT hook motif Pkinase PF00069.20 EPS27315.1 - 1.1e-58 198.4 0.0 1.6e-58 197.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS27315.1 - 4.3e-35 121.0 0.1 1.7e-33 115.8 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EPS27315.1 - 2e-07 30.3 0.0 6.9e-07 28.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EPS27315.1 - 0.0014 18.3 0.1 0.0035 17.1 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Sybindin PF04099.7 EPS27316.1 - 3.2e-26 91.7 0.0 4e-26 91.4 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EPS27316.1 - 0.00057 19.7 0.1 0.00083 19.2 0.1 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Pkinase PF00069.20 EPS27319.1 - 1.3e-62 211.3 0.0 2.1e-62 210.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS27319.1 - 4.1e-26 91.6 0.0 6e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EPS27319.1 - 0.0082 15.2 0.0 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EPS27319.1 - 0.016 14.1 0.0 0.033 13.1 0.0 1.5 1 1 0 1 1 1 0 Kinase-like APH PF01636.18 EPS27319.1 - 0.02 14.6 0.6 1.9 8.1 0.0 3.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family Ndc1_Nup PF09531.5 EPS27319.1 - 1.7 6.9 3.6 2.4 6.4 2.5 1.4 1 1 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PIP49_N PF14875.1 EPS27321.1 - 0.048 13.3 0.0 0.071 12.7 0.0 1.2 1 0 0 1 1 1 0 N-term cysteine-rich ER, FAM69 MFP2b PF12150.3 EPS27323.1 - 0.14 10.8 0.0 0.17 10.5 0.0 1.1 1 0 0 1 1 1 0 Cytosolic motility protein BAR PF03114.13 EPS27325.1 - 3.4e-62 209.9 3.1 4.2e-62 209.6 2.1 1.1 1 0 0 1 1 1 1 BAR domain DUF3987 PF13148.1 EPS27325.1 - 0.096 11.2 4.1 0.12 10.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Pept_tRNA_hydro PF01195.14 EPS27326.1 - 2.6e-20 72.6 0.0 3e-05 23.5 0.0 3.6 3 1 0 3 3 3 3 Peptidyl-tRNA hydrolase Brix PF04427.13 EPS27327.1 - 8.1e-40 136.5 0.1 1.2e-39 135.9 0.0 1.2 1 0 0 1 1 1 1 Brix domain Nop14 PF04147.7 EPS27327.1 - 0.0031 15.5 19.0 0.004 15.1 13.1 1.1 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.9 EPS27327.1 - 0.55 8.1 12.4 0.85 7.5 8.6 1.3 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.6 EPS27327.1 - 2.7 5.7 7.3 3.7 5.2 5.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen tRNA-synt_2b PF00587.20 EPS27328.1 - 1.3e-65 220.1 0.0 3.4e-65 218.8 0.1 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EPS27328.1 - 1.2e-21 76.4 0.0 5.7e-21 74.2 0.0 2.3 1 0 0 1 1 1 1 Anticodon binding domain Pkinase PF00069.20 EPS27329.1 - 5.7e-70 235.4 0.0 1.2e-69 234.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS27329.1 - 5.1e-52 176.5 0.1 9.6e-52 175.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EPS27329.1 - 7.8e-24 83.8 0.7 7.8e-23 80.6 0.0 2.7 2 0 0 2 2 2 1 P21-Rho-binding domain PH_11 PF15413.1 EPS27329.1 - 1.9e-19 69.9 0.4 4.3e-19 68.8 0.2 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EPS27329.1 - 4.1e-08 33.3 0.1 8.5e-08 32.3 0.1 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 EPS27329.1 - 3.2e-07 29.6 0.0 1.2e-06 27.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 EPS27329.1 - 0.017 13.9 0.1 0.028 13.2 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 EPS27329.1 - 0.029 14.1 0.3 0.029 14.1 0.2 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family Acyltransferase PF01553.16 EPS27331.1 - 8.8e-27 93.1 0.0 1.3e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase TPR_2 PF07719.12 EPS27332.1 - 5.3e-29 97.7 27.0 0.00085 19.0 0.1 13.0 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_11 PF13414.1 EPS27332.1 - 4.1e-26 90.4 37.3 2.3e-05 23.9 0.5 11.7 10 4 1 12 12 12 6 TPR repeat TPR_1 PF00515.23 EPS27332.1 - 4e-21 73.6 24.8 0.00027 20.4 0.0 11.8 13 0 0 13 13 13 5 Tetratricopeptide repeat TPR_19 PF14559.1 EPS27332.1 - 1.1e-20 73.6 28.5 2.4e-06 27.8 0.2 10.6 9 3 2 11 11 11 6 Tetratricopeptide repeat TPR_12 PF13424.1 EPS27332.1 - 8.3e-16 57.6 37.1 0.00035 20.4 0.1 10.7 8 3 4 12 12 12 7 Tetratricopeptide repeat TPR_8 PF13181.1 EPS27332.1 - 2.1e-15 55.2 28.5 0.00052 19.6 0.1 11.4 13 0 0 13 13 12 4 Tetratricopeptide repeat TPR_16 PF13432.1 EPS27332.1 - 3.3e-11 43.5 58.1 0.0023 18.5 0.0 13.1 10 2 4 14 14 13 6 Tetratricopeptide repeat TPR_14 PF13428.1 EPS27332.1 - 6.7e-11 41.8 48.9 0.083 13.5 0.0 12.8 12 2 2 14 14 12 5 Tetratricopeptide repeat TPR_6 PF13174.1 EPS27332.1 - 1.7e-10 40.6 23.2 0.016 15.6 0.0 11.8 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_7 PF13176.1 EPS27332.1 - 7.7e-05 22.2 33.0 0.00083 18.9 0.3 10.0 13 0 0 13 13 12 2 Tetratricopeptide repeat TPR_10 PF13374.1 EPS27332.1 - 0.00053 19.8 18.9 0.41 10.6 0.3 7.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 EPS27332.1 - 0.0018 18.3 24.3 0.57 10.5 0.0 10.6 12 0 0 12 12 12 1 Tetratricopeptide repeat DUF3347 PF11827.3 EPS27334.1 - 0.0088 16.0 1.8 0.013 15.5 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3347) DUF1925 PF09094.6 EPS27334.1 - 0.085 12.8 4.6 0.17 11.8 3.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1925) BAF1_ABF1 PF04684.8 EPS27334.1 - 0.52 9.0 7.4 0.66 8.7 5.1 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor RRP14 PF15459.1 EPS27334.1 - 1.2 9.2 13.7 0.26 11.3 5.0 2.3 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 60KD_IMP PF02096.15 EPS27334.1 - 4.7 6.8 7.0 7.1 6.2 4.9 1.2 1 0 0 1 1 1 0 60Kd inner membrane protein Es2 PF09751.4 EPS27339.1 - 2.7e-114 382.8 2.8 3.2e-114 382.5 2.0 1.0 1 0 0 1 1 1 1 Nuclear protein Es2 DUF4515 PF14988.1 EPS27339.1 - 0.027 14.1 2.2 0.088 12.4 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4515) Oxidored-like PF09791.4 EPS27340.1 - 0.00032 20.0 7.3 0.00032 20.0 5.0 1.9 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal Mid1 PF12929.2 EPS27341.1 - 7.3e-154 512.5 7.0 8.7e-154 512.3 4.9 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 EPS27341.1 - 0.15 12.3 2.9 2.5 8.4 1.0 2.6 2 1 0 2 2 2 0 Fz domain CorA PF01544.13 EPS27342.1 - 8.5e-46 156.2 0.0 1.2e-45 155.8 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF3346 PF11826.3 EPS27343.1 - 0.0038 17.0 0.0 0.0045 16.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3346) Tricorn_C1 PF14684.1 EPS27343.1 - 0.087 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Tricorn protease C1 domain GHMP_kinases_N PF00288.21 EPS27344.1 - 3.8e-14 52.4 0.1 7.3e-14 51.5 0.1 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EPS27344.1 - 9.7e-06 25.6 0.0 1.9e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal zf-rbx1 PF12678.2 EPS27346.1 - 8.8e-36 121.8 13.6 1.1e-35 121.5 9.4 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EPS27346.1 - 1.7e-17 62.9 10.4 2.4e-17 62.5 7.2 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EPS27346.1 - 2.9e-07 30.1 12.8 1.8e-06 27.6 8.9 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EPS27346.1 - 0.0018 17.9 12.4 0.03 13.9 8.6 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPS27346.1 - 0.003 17.1 9.6 0.3 10.7 6.8 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPS27346.1 - 0.051 13.6 13.2 1.4 9.0 9.2 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EPS27346.1 - 0.079 12.9 8.7 0.33 10.9 6.1 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 EPS27346.1 - 0.38 10.5 6.4 0.46 10.2 1.3 2.3 1 1 1 2 2 2 0 RING-type zinc-finger zf-HC5HC2H_2 PF13832.1 EPS27346.1 - 0.65 10.0 9.8 1.6 8.7 6.8 1.7 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_5 PF14634.1 EPS27346.1 - 1.1 9.0 11.9 8.9 6.1 8.2 2.4 1 1 0 1 1 1 0 zinc-RING finger domain zf-HC5HC2H PF13771.1 EPS27346.1 - 1.2 9.3 11.1 65 3.7 7.7 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain PNRC PF15365.1 EPS27347.1 - 1.5e-10 40.9 7.7 1.1e-07 31.7 0.9 4.4 3 0 0 3 3 3 2 Proline-rich nuclear receptor coactivator DUF3534 PF12053.3 EPS27347.1 - 4.4 7.1 6.2 1.3 8.8 1.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3534) SMI1_KNR4 PF09346.5 EPS27348.1 - 6.6e-34 116.7 0.0 1.1e-33 116.0 0.0 1.3 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) Thioredoxin PF00085.15 EPS27349.1 - 1.6e-05 24.4 0.0 2.6e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Ank_2 PF12796.2 EPS27351.1 - 2.1e-11 43.9 0.5 0.00016 21.9 0.0 4.0 2 2 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EPS27351.1 - 2.6e-09 36.4 5.1 0.0062 16.2 0.2 5.7 5 1 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 EPS27351.1 - 5.6e-09 35.9 5.5 0.00083 19.5 0.1 5.2 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EPS27351.1 - 1.3e-08 35.1 2.9 0.65 10.5 0.0 5.8 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPS27351.1 - 0.00034 20.5 3.2 23 5.6 0.0 5.6 4 1 1 5 5 5 1 Ankyrin repeat UAA PF08449.6 EPS27352.1 - 1.5e-11 43.7 21.8 1.9e-11 43.4 15.1 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EPS27352.1 - 9.2e-10 38.3 8.2 9.2e-10 38.3 5.7 2.8 1 1 2 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 EPS27352.1 - 0.00057 19.9 7.0 0.00057 19.9 4.9 2.3 2 0 0 2 2 2 1 EamA-like transporter family Multi_Drug_Res PF00893.14 EPS27352.1 - 0.44 11.0 13.1 2.1 8.8 3.5 2.8 2 1 0 2 2 2 0 Small Multidrug Resistance protein Herpes_LMP1 PF05297.6 EPS27352.1 - 1.2 8.0 9.3 0.14 11.1 2.7 1.8 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) Orbi_NS3 PF01616.11 EPS27352.1 - 1.7 7.6 4.1 0.81 8.6 0.3 2.1 2 0 0 2 2 2 0 Orbivirus NS3 DUF2431 PF10354.4 EPS27353.1 - 7.5e-45 152.8 0.0 2.3e-42 144.7 0.0 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF2431) Methyltransf_26 PF13659.1 EPS27353.1 - 0.057 13.4 0.0 0.099 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CDC45 PF02724.9 EPS27353.1 - 0.37 8.7 8.8 0.12 10.3 1.7 2.0 2 0 0 2 2 2 0 CDC45-like protein Nucleoplasmin PF03066.10 EPS27353.1 - 0.49 9.8 9.7 0.077 12.5 0.7 2.3 2 0 0 2 2 2 0 Nucleoplasmin TEX19 PF15553.1 EPS27353.1 - 0.99 9.2 9.2 1.5 8.6 0.7 2.7 2 0 0 2 2 2 0 Testis-expressed protein 19 DUF3537 PF12056.3 EPS27353.1 - 2.8 6.5 3.9 5.1 5.6 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) CLTH PF10607.4 EPS27354.1 - 6e-36 123.2 0.1 1.1e-35 122.4 0.1 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EPS27354.1 - 0.0096 15.6 0.0 0.024 14.4 0.0 1.7 1 0 0 1 1 1 1 LisH DKCLD PF08068.7 EPS27355.1 - 1.9e-28 98.1 0.1 1.3e-27 95.4 0.0 2.3 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 EPS27355.1 - 3.2e-24 85.7 0.2 2.3e-21 76.5 0.1 3.4 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 EPS27355.1 - 7e-22 76.9 1.3 1.3e-21 76.0 0.9 1.5 1 0 0 1 1 1 1 PUA domain Med19 PF10278.4 EPS27355.1 - 0.012 15.3 12.4 0.02 14.5 8.6 1.4 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 TFIIF_alpha PF05793.7 EPS27355.1 - 0.14 10.4 20.5 0.18 10.1 14.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RNase_H2-Ydr279 PF09468.5 EPS27355.1 - 2.2 7.4 9.4 3.2 6.8 6.5 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Peptidase_S49_N PF08496.5 EPS27355.1 - 6 6.6 7.6 11 5.8 5.2 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal RNA_polI_A34 PF08208.6 EPS27355.1 - 6.4 6.3 23.8 10 5.7 16.5 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DDHD PF02862.12 EPS27355.1 - 6.6 6.4 7.7 30 4.3 5.9 1.6 2 0 0 2 2 2 0 DDHD domain DER1 PF04511.10 EPS27356.1 - 4.7e-25 88.2 1.4 5.5e-25 88.0 1.0 1.0 1 0 0 1 1 1 1 Der1-like family MgtE PF01769.11 EPS27356.1 - 0.0022 18.3 0.4 0.0035 17.6 0.3 1.2 1 0 0 1 1 1 1 Divalent cation transporter Papilloma_E5A PF05776.7 EPS27356.1 - 0.093 12.8 5.1 0.37 10.9 2.8 2.1 2 0 0 2 2 2 0 Papillomavirus E5A protein MaoC_dehydratas PF01575.14 EPS27357.1 - 0.0009 18.6 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain PDT PF00800.13 EPS27358.1 - 5.4e-69 231.3 0.0 6.9e-69 231.0 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydratase ACT PF01842.20 EPS27358.1 - 0.00076 18.9 0.0 0.0023 17.4 0.0 1.9 2 0 0 2 2 2 1 ACT domain eRF1_2 PF03464.10 EPS27359.1 - 2.9e-47 160.3 0.1 4.9e-47 159.5 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EPS27359.1 - 1e-39 135.2 0.3 2.4e-39 134.0 0.2 1.7 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EPS27359.1 - 6.1e-29 100.2 0.0 1.1e-28 99.4 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 Ribosomal_L7Ae PF01248.21 EPS27359.1 - 0.11 12.0 0.0 0.25 10.8 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Aa_trans PF01490.13 EPS27360.1 - 4.6e-65 219.6 20.9 5.3e-65 219.4 14.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EPS27360.1 - 0.033 13.0 14.4 0.018 13.8 5.2 2.3 2 0 0 2 2 2 0 Tryptophan/tyrosine permease family DUF3321 PF11968.3 EPS27361.1 - 5e-91 304.2 0.0 6.4e-91 303.8 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Ribosomal_L23eN PF03939.8 EPS27362.1 - 3.2e-21 75.1 6.7 3.2e-21 75.1 4.6 1.7 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 EPS27362.1 - 2.6e-18 65.7 1.6 5.6e-18 64.6 1.1 1.6 1 1 0 1 1 1 1 Ribosomal protein L23 zf-Tim10_DDP PF02953.10 EPS27363.1 - 5.4e-21 73.6 4.5 6.5e-21 73.4 3.1 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF4280 PF14107.1 EPS27363.1 - 0.016 15.4 0.3 0.019 15.2 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4280) LRR_5 PF13306.1 EPS27363.1 - 0.051 13.2 0.3 0.062 13.0 0.2 1.1 1 0 0 1 1 1 0 Leucine rich repeats (6 copies) G10 PF01125.12 EPS27364.1 - 1.2e-65 219.4 4.5 1.4e-65 219.3 3.1 1.0 1 0 0 1 1 1 1 G10 protein DNA_RNApol_7kD PF03604.8 EPS27364.1 - 1.3 8.6 9.1 0.48 9.9 3.7 2.1 1 1 1 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Fork_head PF00250.13 EPS27365.1 - 1.2e-36 124.5 0.1 2.2e-36 123.7 0.1 1.4 1 0 0 1 1 1 1 Fork head domain AA_kinase PF00696.23 EPS27368.1 - 5.1e-42 144.0 0.1 7.9e-42 143.4 0.1 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.1 EPS27368.1 - 3.7e-12 45.5 1.2 3.2e-10 39.3 0.1 2.4 2 0 0 2 2 2 2 ACT domain ACT PF01842.20 EPS27368.1 - 2.1e-11 43.0 2.7 2e-09 36.7 0.1 3.4 3 0 0 3 3 3 2 ACT domain Glyco_trans_1_3 PF13528.1 EPS27369.1 - 0.015 14.4 0.1 0.12 11.5 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 1 Eaf7 PF07904.8 EPS27369.1 - 0.022 14.6 0.0 0.17 11.8 0.0 2.2 2 0 0 2 2 2 0 Chromatin modification-related protein EAF7 AAA PF00004.24 EPS27370.1 - 2.4e-16 60.1 0.0 5.8e-16 58.8 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EPS27370.1 - 0.0027 17.4 0.1 0.008 15.9 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EPS27370.1 - 0.012 15.5 0.0 0.04 13.9 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain Torsin PF06309.6 EPS27370.1 - 0.16 11.8 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_22 PF13401.1 EPS27370.1 - 0.17 12.0 0.1 0.17 12.0 0.1 3.0 2 1 1 3 3 3 0 AAA domain Peptidase_C78 PF07910.8 EPS27371.1 - 1.7e-73 246.3 0.0 2.4e-73 245.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 zf-C2H2_4 PF13894.1 EPS27371.1 - 0.005 17.0 3.3 3.7 8.1 0.0 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 EPS27371.1 - 0.0066 16.5 5.9 0.46 10.6 0.8 2.6 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 EPS27371.1 - 0.77 10.2 6.3 3 8.3 1.3 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type AAA_18 PF13238.1 EPS27372.1 - 3.8e-26 91.9 0.4 5.6e-26 91.3 0.0 1.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EPS27372.1 - 1.7e-13 51.4 1.1 3.9e-13 50.2 0.8 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EPS27372.1 - 0.00011 22.1 0.0 0.0033 17.3 0.0 2.2 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.1 EPS27372.1 - 0.00029 20.8 0.2 0.00036 20.5 0.2 1.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EPS27372.1 - 0.00076 19.6 0.0 0.0012 19.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EPS27372.1 - 0.0017 18.5 0.0 0.0026 17.9 0.0 1.3 1 0 0 1 1 1 1 RNA helicase ADK PF00406.17 EPS27372.1 - 0.0028 17.5 0.0 0.014 15.2 0.0 2.0 2 0 0 2 2 2 1 Adenylate kinase AAA_14 PF13173.1 EPS27372.1 - 0.0049 16.7 0.0 0.0098 15.7 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EPS27372.1 - 0.0066 16.6 0.0 0.013 15.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EPS27372.1 - 0.0099 15.1 0.0 0.018 14.2 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_16 PF13191.1 EPS27372.1 - 0.011 15.7 0.0 0.016 15.1 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain Cytidylate_kin2 PF13189.1 EPS27372.1 - 0.015 15.1 0.0 0.022 14.6 0.0 1.6 1 1 0 1 1 1 0 Cytidylate kinase-like family AAA_10 PF12846.2 EPS27372.1 - 0.016 14.6 0.0 0.11 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain NTPase_1 PF03266.10 EPS27372.1 - 0.016 14.8 0.2 0.039 13.6 0.1 1.7 2 0 0 2 2 2 0 NTPase IstB_IS21 PF01695.12 EPS27372.1 - 0.052 12.9 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein CoaE PF01121.15 EPS27372.1 - 0.12 11.7 0.0 4.9 6.5 0.0 2.2 2 0 0 2 2 2 0 Dephospho-CoA kinase Viral_helicase1 PF01443.13 EPS27372.1 - 0.12 11.8 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Ham1p_like PF01725.11 EPS27373.1 - 2.6e-56 190.0 0.0 2.9e-56 189.8 0.0 1.0 1 0 0 1 1 1 1 Ham1 family DUF719 PF05334.8 EPS27373.1 - 0.12 12.3 0.5 0.24 11.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF719) Myosin_head PF00063.16 EPS27374.1 - 5.7e-247 821.1 3.2 8.3e-247 820.6 2.2 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.14 EPS27374.1 - 3.7e-34 116.7 3.9 3.7e-34 116.7 2.7 2.5 2 1 1 3 3 3 1 DIL domain IQ PF00612.22 EPS27374.1 - 1.7e-16 58.1 28.4 9.5e-05 21.7 0.0 7.1 6 0 0 6 6 6 6 IQ calmodulin-binding motif AAA_22 PF13401.1 EPS27374.1 - 4.3e-05 23.6 0.0 0.00037 20.6 0.0 2.7 1 0 0 1 1 1 1 AAA domain Myosin_N PF02736.14 EPS27374.1 - 0.0014 18.2 1.1 0.0036 16.9 0.7 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_16 PF13191.1 EPS27374.1 - 0.0043 17.0 0.6 0.07 13.1 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 EPS27374.1 - 0.0093 15.1 0.0 0.025 13.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_19 PF13245.1 EPS27374.1 - 0.012 15.3 0.0 0.055 13.2 0.0 2.2 1 0 0 1 1 1 0 Part of AAA domain AAA_10 PF12846.2 EPS27374.1 - 0.024 14.0 0.3 0.13 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain RNA_helicase PF00910.17 EPS27374.1 - 0.084 13.0 0.0 0.54 10.4 0.0 2.5 2 0 0 2 2 2 0 RNA helicase GAS PF13851.1 EPS27374.1 - 1.9 7.6 24.9 0.84 8.7 8.2 2.6 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Pterin_bind PF00809.17 EPS27375.1 - 0.058 12.7 0.0 0.068 12.5 0.0 1.1 1 0 0 1 1 1 0 Pterin binding enzyme NAP PF00956.13 EPS27376.1 - 4.1e-87 291.3 11.3 4.1e-87 291.3 7.8 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Afaf PF15339.1 EPS27376.1 - 0.86 9.1 5.7 0.16 11.5 0.7 1.9 2 0 0 2 2 2 0 Acrosome formation-associated factor Sigma70_ner PF04546.8 EPS27376.1 - 9.5 5.7 32.4 1.2 8.6 6.5 2.6 2 1 0 2 2 2 0 Sigma-70, non-essential region P5-ATPase PF12409.3 EPS27378.1 - 2.3e-38 130.7 0.0 6.6e-38 129.2 0.0 1.9 1 0 0 1 1 1 1 P5-type ATPase cation transporter HAD PF12710.2 EPS27378.1 - 1.2e-32 113.6 0.0 4.1e-32 111.9 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EPS27378.1 - 8.2e-31 106.8 0.0 2e-30 105.5 0.0 1.6 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EPS27378.1 - 1e-18 68.5 0.0 2.6e-17 63.9 0.0 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPS27378.1 - 7.2e-05 22.6 0.0 0.00019 21.3 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EPS27378.1 - 0.012 15.1 0.1 1.4 8.4 0.0 2.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EPS27378.1 - 0.18 11.3 0.0 0.46 9.9 0.0 1.7 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus NADH_B2 PF14813.1 EPS27379.1 - 0.026 14.1 0.2 0.027 14.1 0.2 1.1 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 Pkinase PF00069.20 EPS27380.1 - 4.5e-68 229.2 0.0 5.4e-68 228.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS27380.1 - 4.2e-33 114.5 0.0 5.5e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPS27380.1 - 0.13 11.2 0.0 0.25 10.2 0.0 1.5 1 1 0 1 1 1 0 Kinase-like 2-Hacid_dh_C PF02826.14 EPS27381.1 - 3.9e-51 172.7 0.0 6.3e-51 172.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EPS27381.1 - 1.3e-36 125.0 0.0 1.7e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EPS27381.1 - 5.4e-05 23.0 0.2 0.00013 21.8 0.1 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.20 EPS27381.1 - 0.0014 18.0 0.0 0.0036 16.7 0.0 1.7 1 0 0 1 1 1 1 ACT domain IlvN PF07991.7 EPS27381.1 - 0.0047 16.2 0.2 0.18 11.1 0.0 2.3 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain AdoHcyase_NAD PF00670.16 EPS27381.1 - 0.02 14.7 0.0 0.048 13.4 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.1 EPS27381.1 - 0.051 13.8 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain 3HCDH_N PF02737.13 EPS27381.1 - 0.096 12.3 0.7 0.27 10.8 0.1 2.1 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain tRNA-synt_2b PF00587.20 EPS27382.1 - 6.5e-32 110.4 0.0 1.1e-31 109.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EPS27382.1 - 5.8e-19 68.1 7.0 5.8e-19 68.1 4.9 2.5 3 0 0 3 3 3 1 Seryl-tRNA synthetase N-terminal domain Cytochrom_C552 PF02335.10 EPS27382.1 - 0.38 9.3 8.1 0.26 9.9 0.1 2.3 2 0 0 2 2 2 0 Cytochrome c552 DUF4375 PF14300.1 EPS27382.1 - 3 7.8 7.2 0.5 10.3 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4375) Ras PF00071.17 EPS27383.1 - 5.7e-46 155.8 0.2 6.5e-46 155.6 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPS27383.1 - 4.7e-16 59.3 0.1 6.3e-16 58.9 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPS27383.1 - 4.6e-09 35.7 0.0 5e-09 35.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EPS27383.1 - 7.7e-07 28.7 0.2 4.8e-05 22.8 0.1 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EPS27383.1 - 1.2e-06 28.4 0.1 2e-06 27.7 0.1 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EPS27383.1 - 0.00029 20.1 0.0 0.00043 19.5 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_28 PF13521.1 EPS27383.1 - 0.0083 16.1 0.0 0.017 15.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EPS27383.1 - 0.012 15.4 0.1 0.019 14.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 EPS27383.1 - 0.13 11.5 0.0 0.3 10.3 0.0 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B WAPL PF07814.8 EPS27384.1 - 8.3e-38 130.0 2.4 1.4e-37 129.3 1.6 1.4 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin Creb_binding PF09030.5 EPS27384.1 - 0.069 13.3 0.0 0.069 13.3 0.0 3.3 4 0 0 4 4 4 0 Creb binding UPRTase PF14681.1 EPS27385.1 - 2.3e-77 258.8 0.0 2.9e-77 258.5 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EPS27385.1 - 0.0019 17.9 0.0 0.0032 17.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 EPS27385.1 - 0.089 12.5 0.2 0.14 11.8 0.2 1.2 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Elf1 PF05129.8 EPS27386.1 - 8.3e-29 99.1 0.1 1e-28 98.8 0.1 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-Sec23_Sec24 PF04810.10 EPS27386.1 - 0.03 13.8 0.7 1.5 8.4 0.1 2.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-C2H2_6 PF13912.1 EPS27386.1 - 0.27 11.2 0.3 0.27 11.2 0.2 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger Ribosomal_S3Ae PF01015.13 EPS27387.1 - 2e-80 268.7 5.3 2.3e-80 268.5 3.7 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Prok-RING_2 PF14445.1 EPS27388.1 - 0.16 11.9 0.8 8 6.4 0.3 2.6 2 1 0 2 2 2 0 Prokaryotic RING finger family 2 adh_short PF00106.20 EPS27392.1 - 4.4e-13 49.4 0.0 7.2e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPS27392.1 - 3.2e-05 23.6 0.0 5.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EPS27392.1 - 0.0028 17.7 0.0 0.014 15.3 0.0 2.0 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EPS27392.1 - 0.0081 15.6 0.0 0.021 14.2 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EPS27392.1 - 0.074 13.1 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3A PF00803.13 EPS27392.1 - 0.17 10.9 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 3A/RNA2 movement protein family SseC PF04888.7 EPS27393.1 - 0.0071 15.7 12.3 0.008 15.5 8.5 1.0 1 0 0 1 1 1 1 Secretion system effector C (SseC) like family YpjP PF14005.1 EPS27393.1 - 0.024 14.3 1.1 0.03 14.1 0.8 1.1 1 0 0 1 1 1 0 YpjP-like protein Mor PF08765.6 EPS27393.1 - 0.21 11.3 2.0 0.74 9.6 1.3 1.9 1 1 0 1 1 1 0 Mor transcription activator family Fungal_trans PF04082.13 EPS27395.1 - 4.3e-11 42.1 0.3 6.7e-11 41.5 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS27395.1 - 9.5e-08 31.8 10.9 2.4e-07 30.5 7.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HTH_41 PF14502.1 EPS27395.1 - 0.07 12.7 0.1 0.27 10.8 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain SWIRM PF04433.12 EPS27397.1 - 8.6e-14 51.4 0.0 1.6e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain CDC50 PF03381.10 EPS27398.1 - 2.6e-97 325.3 0.0 3.3e-97 325.0 0.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF4282 PF14110.1 EPS27398.1 - 0.31 11.2 2.6 4.8 7.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) Peptidase_M43 PF05572.8 EPS27399.1 - 1.8e-11 43.8 0.0 3.7e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 EPS27399.1 - 0.0032 17.4 5.9 0.012 15.5 4.1 1.9 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 EPS27399.1 - 0.0034 16.9 0.1 0.0043 16.5 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like SopD PF11047.3 EPS27399.1 - 0.024 13.5 0.0 0.033 13.1 0.0 1.1 1 0 0 1 1 1 0 Salmonella outer protein D Reprolysin_2 PF13574.1 EPS27399.1 - 0.034 14.2 0.8 0.056 13.4 0.5 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 EPS27399.1 - 0.1 11.4 0.1 0.15 10.8 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 SPT16 PF08644.6 EPS27400.1 - 1.9e-60 203.1 0.0 1.9e-60 203.1 0.0 2.0 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 EPS27400.1 - 4.3e-54 182.4 0.3 1.5e-53 180.6 0.2 2.0 1 0 0 1 1 1 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 EPS27400.1 - 2.5e-23 82.7 0.0 4.2e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 EPS27400.1 - 2.1e-20 72.5 0.0 5.5e-20 71.1 0.0 1.8 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Mito_carr PF00153.22 EPS27401.1 - 2.5e-21 75.1 3.3 9.9e-16 57.2 0.0 3.5 3 1 0 3 3 3 2 Mitochondrial carrier protein Sugar_tr PF00083.19 EPS27402.1 - 2.6e-100 336.1 17.4 3.1e-100 335.9 12.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS27402.1 - 4.3e-31 107.8 53.1 1.3e-27 96.4 16.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EPS27402.1 - 2.5e-09 36.0 16.9 3.6e-05 22.3 2.5 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 EPS27402.1 - 0.0062 16.3 0.3 0.028 14.2 0.0 2.2 2 0 0 2 2 2 1 MFS_1 like family PMT PF02366.13 EPS27403.1 - 1.6e-84 283.1 15.8 1.6e-84 283.1 10.9 2.6 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EPS27403.1 - 2.5e-37 128.2 0.3 3.5e-37 127.7 0.2 1.2 1 0 0 1 1 1 1 MIR domain Ras PF00071.17 EPS27404.1 - 4.1e-48 162.8 0.0 1.7e-37 128.2 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EPS27404.1 - 1e-14 55.0 0.0 1.8e-09 38.0 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein Arf PF00025.16 EPS27404.1 - 4.6e-12 45.5 0.0 2.1e-11 43.3 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EPS27404.1 - 6.4e-10 38.7 0.0 4e-09 36.1 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EPS27404.1 - 7.8e-06 25.1 0.1 2.9e-05 23.3 0.1 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EPS27404.1 - 0.00073 19.4 0.0 0.0055 16.6 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Flu_M1_C PF08289.6 EPS27404.1 - 0.017 15.1 0.1 0.029 14.3 0.1 1.3 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain AAA_30 PF13604.1 EPS27404.1 - 0.019 14.5 0.2 0.26 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EPS27404.1 - 0.029 14.5 0.0 0.53 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EPS27404.1 - 0.056 12.8 0.0 8.4 5.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EPS27404.1 - 0.13 11.4 0.0 0.29 10.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EPS27404.1 - 0.22 11.4 1.0 0.74 9.7 0.2 1.9 2 0 0 2 2 2 0 AAA ATPase domain Choline_transpo PF04515.7 EPS27405.1 - 1.3e-06 27.3 20.1 1.3e-06 27.3 13.9 3.2 2 1 1 3 3 3 3 Plasma-membrane choline transporter Aldo_ket_red PF00248.16 EPS27407.1 - 2.8e-46 157.6 0.0 3.7e-46 157.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family UPF0061 PF02696.9 EPS27408.1 - 8.8e-119 396.9 0.0 1.1e-118 396.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family zf-CCHC PF00098.18 EPS27409.1 - 2.9e-51 169.0 59.4 8.7e-09 34.9 1.0 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 EPS27409.1 - 3.9e-14 52.0 41.2 0.05 13.2 0.5 7.0 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.1 EPS27409.1 - 2.3e-06 27.2 51.4 0.004 16.8 1.1 7.0 2 2 5 7 7 7 6 Zinc knuckle zf-CCHC_6 PF15288.1 EPS27409.1 - 0.00038 20.0 48.4 0.03 13.9 1.8 6.8 6 1 1 7 7 7 6 Zinc knuckle zf-CCHC_2 PF13696.1 EPS27409.1 - 0.003 17.0 0.4 0.003 17.0 0.2 7.1 3 2 4 7 7 7 4 Zinc knuckle F-box-like PF12937.2 EPS27410.1 - 8.1e-09 35.0 0.6 2.3e-08 33.6 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EPS27410.1 - 3.9e-08 32.7 1.9 9.4e-08 31.5 1.3 1.7 1 0 0 1 1 1 1 F-box domain WD40 PF00400.27 EPS27410.1 - 6.1e-05 22.7 3.3 0.33 10.8 0.1 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat SAE2 PF08573.5 EPS27411.1 - 2.3e-27 95.5 1.0 2.3e-27 95.5 0.7 3.2 3 0 0 3 3 3 1 DNA repair protein endonuclease SAE2/CtIP C-terminus Baculo_PEP_C PF04513.7 EPS27411.1 - 1.8 8.3 4.7 0.52 10.1 1.1 1.7 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pex16 PF08610.5 EPS27412.1 - 4.8e-116 387.4 0.1 5.5e-116 387.2 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) RNase_HII PF01351.13 EPS27413.1 - 6.6e-45 153.2 0.0 1.4e-44 152.1 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease HII CENP-C_C PF11699.3 EPS27414.1 - 4.1e-35 119.6 0.8 7e-35 118.8 0.6 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.1 EPS27414.1 - 1.5e-25 90.3 5.2 1.5e-25 90.3 3.6 3.8 4 1 1 5 5 5 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.6 EPS27414.1 - 2.2e-05 23.8 0.0 7.3e-05 22.1 0.0 1.9 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EPS27414.1 - 0.081 12.3 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Cupin CAP_GLY PF01302.20 EPS27415.1 - 3.1e-26 90.8 0.0 4.7e-26 90.2 0.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 EPS27415.1 - 1.2e-15 57.4 0.0 1.9e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 EPS27415.1 - 5.5e-06 25.6 0.0 3.6e-05 23.0 0.0 2.2 1 1 0 1 1 1 1 Ubiquitin family Methyltransf_11 PF08241.7 EPS27416.1 - 4.8e-15 55.8 0.1 9.1e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPS27416.1 - 6.5e-09 36.0 0.1 1.1e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPS27416.1 - 9.2e-09 35.2 0.0 1.7e-08 34.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPS27416.1 - 8.7e-07 29.3 0.1 1.5e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPS27416.1 - 2.3e-06 27.2 0.0 3.8e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS27416.1 - 0.0019 18.7 0.0 0.004 17.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EPS27416.1 - 0.003 17.2 0.0 0.0042 16.7 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase MetW PF07021.7 EPS27416.1 - 0.017 14.4 0.1 0.036 13.4 0.1 1.5 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.6 EPS27416.1 - 0.083 11.5 0.1 0.36 9.4 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) TehB PF03848.9 EPS27416.1 - 0.14 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB Myb_DNA-binding PF00249.26 EPS27417.1 - 1.2e-11 44.4 2.8 1.9e-09 37.4 0.1 2.8 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EPS27417.1 - 2e-07 30.9 5.1 4.5e-05 23.4 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain CobT PF06213.7 EPS27418.1 - 0.13 11.4 10.3 0.13 11.3 7.2 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2992 PF11208.3 EPS27418.1 - 0.54 10.1 17.8 0.64 9.9 12.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) DUF2413 PF10310.4 EPS27418.1 - 0.81 8.4 13.3 0.86 8.3 9.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF1510 PF07423.6 EPS27418.1 - 1.2 8.4 16.0 1.3 8.3 11.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF3464 PF11947.3 EPS27418.1 - 1.9 7.9 8.7 2.4 7.6 6.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Glyco_transf_15 PF01793.11 EPS27418.1 - 2.3 7.0 5.5 2.6 6.8 3.8 1.2 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Rubella_Capsid PF05750.6 EPS27418.1 - 4.4 6.5 11.9 4.6 6.5 8.2 1.1 1 0 0 1 1 1 0 Rubella capsid protein Presenilin PF01080.12 EPS27418.1 - 8.9 5.0 5.9 9.4 4.9 4.1 1.0 1 0 0 1 1 1 0 Presenilin eIF-3_zeta PF05091.7 EPS27418.1 - 9 4.7 15.6 9.3 4.7 10.8 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MIP-T3 PF10243.4 EPS27418.1 - 9.6 4.5 31.6 11 4.3 21.9 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Nucleoplasmin PF03066.10 EPS27420.1 - 0.033 13.6 0.8 0.038 13.4 0.5 1.2 1 0 0 1 1 1 0 Nucleoplasmin Ribosomal_60s PF00428.14 EPS27420.1 - 1 9.8 12.6 1.6 9.1 8.7 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein BSP_II PF05432.6 EPS27420.1 - 2.1 7.5 9.3 2.9 7.1 6.5 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) UCH PF00443.24 EPS27421.1 - 2.6e-27 95.5 1.0 3.8e-27 95.0 0.7 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPS27421.1 - 4e-12 46.1 1.5 9.3e-12 44.9 1.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MitMem_reg PF13012.1 EPS27423.1 - 5e-40 136.1 0.5 1e-39 135.1 0.2 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EPS27423.1 - 4.3e-29 100.5 0.1 1e-28 99.3 0.0 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF884 PF05959.6 EPS27423.1 - 0.028 13.7 0.0 0.047 12.9 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF884) ADK PF00406.17 EPS27424.1 - 7.9e-59 197.8 0.0 1e-58 197.5 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EPS27424.1 - 8.7e-16 57.3 0.0 2.4e-15 55.8 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.1 EPS27424.1 - 1.2e-05 25.1 0.0 2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPS27424.1 - 0.00014 22.6 0.0 0.00025 21.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EPS27424.1 - 0.00039 19.5 0.0 0.00059 18.9 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 EPS27424.1 - 0.017 15.4 0.1 0.038 14.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 EPS27424.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Thymidylate kinase GFO_IDH_MocA PF01408.17 EPS27425.1 - 3.2e-18 66.4 0.1 5.1e-18 65.7 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Attachment_P66 PF11263.3 EPS27425.1 - 0.015 14.3 0.0 0.028 13.4 0.0 1.4 1 0 0 1 1 1 0 Borrelia burgdorferi attachment protein P66 NAD_binding_3 PF03447.11 EPS27425.1 - 0.03 14.7 0.1 0.05 13.9 0.0 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain CTD_bind PF04818.8 EPS27426.1 - 0.0034 17.6 0.0 0.009 16.2 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CFIA_Pcf11 PF11526.3 EPS27426.1 - 0.0051 16.9 0.2 0.014 15.5 0.1 1.7 1 0 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 VHS PF00790.14 EPS27426.1 - 0.028 14.0 0.0 0.056 13.0 0.0 1.4 1 0 0 1 1 1 0 VHS domain zf-C2H2_6 PF13912.1 EPS27426.1 - 0.88 9.5 3.3 7.2 6.6 0.3 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EPS27426.1 - 1.2 8.9 6.1 2.5 7.8 0.1 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Inhibitor_I9 PF05922.11 EPS27427.1 - 0.01 16.4 0.0 0.013 16.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase inhibitor I9 HOOK PF05622.7 EPS27428.1 - 5.1e-26 90.7 52.2 5.1e-26 90.7 36.1 2.7 1 1 2 3 3 3 1 HOOK protein Reo_sigmaC PF04582.7 EPS27428.1 - 0.0076 15.4 2.0 0.0076 15.4 1.4 3.3 3 1 2 5 5 5 2 Reovirus sigma C capsid protein BLOC1_2 PF10046.4 EPS27428.1 - 1.2 9.2 54.2 3.3 7.9 2.9 7.2 2 2 4 7 7 7 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.5 EPS27428.1 - 2.9 7.9 54.1 0.03 14.4 4.7 5.9 3 2 4 7 7 7 0 Fibrinogen alpha/beta chain family GAS PF13851.1 EPS27428.1 - 5.9 6.0 73.0 0.79 8.8 6.4 5.2 2 2 3 5 5 5 0 Growth-arrest specific micro-tubule binding CCDC155 PF14662.1 EPS27428.1 - 7.5 6.1 76.1 3 7.4 12.2 4.9 2 2 2 4 4 4 0 Coiled-coil region of CCDC155 Coprogen_oxidas PF01218.13 EPS27429.1 - 2.5e-120 400.5 0.0 4.3e-120 399.7 0.0 1.4 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase Fungal_trans PF04082.13 EPS27430.1 - 7.8e-21 74.1 0.3 1.3e-20 73.3 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS27430.1 - 4.8e-08 32.7 10.3 8.8e-08 31.9 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Innate_immun PF12782.2 EPS27430.1 - 0.29 10.3 15.0 0.56 9.3 10.4 1.4 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Zip PF02535.17 EPS27430.1 - 0.68 8.8 4.2 1.3 7.9 2.9 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Atg8 PF02991.11 EPS27432.1 - 2.5e-51 171.9 0.2 3e-51 171.7 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EPS27432.1 - 2.5e-06 27.5 0.0 3e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Mito_carr PF00153.22 EPS27434.1 - 3.9e-28 96.9 0.8 5.2e-15 54.9 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2665 PF11654.3 EPS27435.1 - 1.1e-05 24.9 0.3 2.4e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2665) HSP70 PF00012.15 EPS27436.1 - 1.6e-272 904.8 7.8 1.8e-272 904.6 5.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EPS27436.1 - 2.8e-19 68.8 0.1 3.1e-18 65.4 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EPS27436.1 - 0.0013 18.4 0.0 0.0028 17.2 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EPS27436.1 - 0.0019 18.0 2.8 0.81 9.5 0.1 3.4 2 2 0 2 2 2 2 Cell division protein FtsA Hydantoinase_A PF01968.13 EPS27436.1 - 0.0065 15.5 0.1 0.039 13.0 0.0 2.1 1 1 1 2 2 2 1 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.15 EPS27436.1 - 0.019 14.2 0.1 1.6 7.9 0.0 2.4 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.6 EPS27436.1 - 0.046 12.6 0.0 0.095 11.6 0.0 1.5 1 0 0 1 1 1 0 StbA protein Macoilin PF09726.4 EPS27436.1 - 0.2 9.8 6.4 0.063 11.5 1.5 1.8 1 1 0 2 2 2 0 Transmembrane protein OPT PF03169.10 EPS27437.1 - 9.5e-136 453.7 48.1 1.1e-135 453.5 33.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3040 PF11239.3 EPS27437.1 - 0.76 9.8 2.6 28 4.8 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) CHZ PF09649.5 EPS27438.1 - 1.2e-13 50.0 4.9 1.2e-13 50.0 3.4 1.8 2 0 0 2 2 2 1 Histone chaperone domain CHZ NCKAP5 PF15246.1 EPS27438.1 - 0.014 14.7 0.9 0.02 14.2 0.7 1.1 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein SNARE PF05739.14 EPS27439.1 - 8.4e-07 28.5 0.9 1.1e-06 28.2 0.6 1.2 1 0 0 1 1 1 1 SNARE domain Apc15p PF05841.6 EPS27440.1 - 4.2e-24 85.6 4.7 7.4e-24 84.8 0.7 2.4 2 0 0 2 2 2 1 Apc15p protein Nop14 PF04147.7 EPS27442.1 - 0.63 7.8 5.6 0.82 7.5 3.9 1.0 1 0 0 1 1 1 0 Nop14-like family Glu_synthase PF01645.12 EPS27443.1 - 1.1e-160 534.6 0.0 1.5e-160 534.1 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 EPS27443.1 - 3.2e-140 466.9 0.0 4.3e-140 466.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 EPS27443.1 - 5.9e-118 393.3 0.0 1.2e-117 392.2 0.0 1.5 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.14 EPS27443.1 - 3.2e-66 222.2 2.3 5.9e-66 221.3 1.6 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 EPS27443.1 - 2.5e-22 78.5 0.0 5.9e-22 77.3 0.0 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 EPS27443.1 - 2.6e-19 69.8 0.0 7.7e-19 68.3 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPS27443.1 - 1.3e-11 44.9 1.0 4.9e-05 23.4 0.1 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPS27443.1 - 3e-09 37.1 0.1 1.2e-05 25.6 0.0 2.9 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPS27443.1 - 5.2e-09 36.0 0.0 2.3e-08 33.9 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EPS27443.1 - 2.7e-06 26.7 0.1 4.7e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 EPS27443.1 - 2.9e-06 26.4 1.3 0.00021 20.2 0.2 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EPS27443.1 - 1.1e-05 24.1 0.3 2.5e-05 22.9 0.2 1.6 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EPS27443.1 - 2e-05 23.6 0.2 0.00017 20.5 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 EPS27443.1 - 2.5e-05 23.5 0.3 4.8e-05 22.6 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 EPS27443.1 - 0.00049 20.3 1.3 0.47 10.7 0.1 3.0 2 0 0 2 2 2 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 EPS27443.1 - 0.00049 19.6 0.1 0.023 14.2 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 EPS27443.1 - 0.0018 17.3 0.0 0.0039 16.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EPS27443.1 - 0.0021 17.1 0.2 0.009 15.1 0.1 2.0 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 EPS27443.1 - 0.0062 15.4 0.2 0.0062 15.4 0.1 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.18 EPS27443.1 - 0.016 14.9 0.1 0.035 13.8 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.15 EPS27443.1 - 0.036 14.1 0.1 18 5.4 0.0 2.9 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase FMO-like PF00743.14 EPS27443.1 - 0.041 12.0 0.1 1.4 6.9 0.0 2.7 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like NAD_binding_2 PF03446.10 EPS27443.1 - 0.06 13.1 0.1 0.17 11.6 0.1 1.8 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DJ-1_PfpI PF01965.19 EPS27443.1 - 0.11 11.9 0.0 0.28 10.6 0.0 1.7 1 1 0 1 1 1 0 DJ-1/PfpI family AdoHcyase_NAD PF00670.16 EPS27443.1 - 0.12 12.1 0.9 7.6 6.3 0.1 2.8 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EPS27443.1 - 0.14 11.2 0.0 0.42 9.7 0.0 1.7 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EPS27443.1 - 2.2 7.8 5.2 0.25 11.0 0.3 1.9 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3128 PF11326.3 EPS27444.1 - 1.1e-28 99.1 1.6 2.1e-28 98.2 1.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) RNA12 PF10443.4 EPS27445.1 - 2.7e-168 559.9 0.0 4e-168 559.3 0.0 1.2 1 0 0 1 1 1 1 RNA12 protein Arch_ATPase PF01637.13 EPS27445.1 - 3.8e-07 30.0 0.0 1.6e-06 27.9 0.0 2.0 1 1 0 1 1 1 1 Archaeal ATPase RRM_1 PF00076.17 EPS27445.1 - 8.1e-05 22.1 0.0 0.00025 20.5 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TIR_2 PF13676.1 EPS27445.1 - 0.00026 21.0 1.6 0.27 11.3 0.0 4.2 4 0 0 4 4 4 1 TIR domain AAA_16 PF13191.1 EPS27445.1 - 0.0011 19.0 0.1 0.027 14.4 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EPS27445.1 - 0.0038 17.1 0.1 0.43 10.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF2487 PF10673.4 EPS27445.1 - 0.0057 16.4 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2487) AAA_22 PF13401.1 EPS27445.1 - 0.078 13.1 0.0 0.84 9.7 0.0 2.7 2 1 0 2 2 2 0 AAA domain p450 PF00067.17 EPS27446.1 - 1.4e-15 56.7 0.0 8.7e-12 44.2 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 WD40 PF00400.27 EPS27448.1 - 1.9e-20 71.9 0.7 8.9e-10 38.0 0.0 6.6 7 0 0 7 7 7 3 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EPS27448.1 - 1.7e-07 30.3 0.0 1.5e-06 27.2 0.0 2.1 1 1 1 2 2 2 1 Coatomer WD associated region DUF3639 PF12341.3 EPS27448.1 - 7.1e-07 29.1 0.5 7.1e-07 29.1 0.4 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3639) eIF2A PF08662.6 EPS27448.1 - 6.5e-06 25.9 0.2 8.4e-05 22.3 0.0 2.6 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.1 EPS27448.1 - 0.018 15.2 3.5 33 4.9 0.8 5.1 4 1 0 4 4 4 0 PQQ-like domain Lactonase PF10282.4 EPS27448.1 - 0.023 13.7 0.0 0.33 9.9 0.0 2.5 2 1 0 2 2 2 0 Lactonase, 7-bladed beta-propeller DNA_pol_alpha_N PF12254.3 EPS27448.1 - 0.026 14.3 4.6 0.064 13.0 3.2 1.6 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal DUF3312 PF11768.3 EPS27448.1 - 0.067 11.4 0.0 1.6 6.8 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3312) IKI3 PF04762.7 EPS27448.1 - 0.3 8.8 0.2 0.86 7.3 0.1 1.6 1 1 0 1 1 1 0 IKI3 family ILVD_EDD PF00920.16 EPS27449.1 - 7.7e-163 542.6 0.2 8.7e-163 542.4 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family Inhibitor_I78 PF11720.3 EPS27449.1 - 0.01 15.5 0.0 0.32 10.7 0.0 2.4 2 0 0 2 2 2 0 Peptidase inhibitor I78 family DAO PF01266.19 EPS27450.1 - 5.7e-49 166.9 0.0 1e-48 166.0 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EPS27450.1 - 1.4e-06 28.1 0.1 0.0084 15.9 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.17 EPS27450.1 - 6.2e-06 25.3 0.0 9.1e-05 21.4 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EPS27450.1 - 7.5e-06 25.0 0.1 0.036 12.9 0.0 2.3 2 1 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EPS27450.1 - 2.3e-05 24.5 0.1 0.0021 18.1 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPS27450.1 - 6.1e-05 22.9 0.0 0.091 12.6 0.0 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPS27450.1 - 0.00046 20.1 0.0 0.0014 18.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EPS27450.1 - 0.00049 18.8 0.3 0.018 13.7 0.1 2.4 2 1 0 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.9 EPS27450.1 - 0.0062 15.0 0.0 0.55 8.6 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Shikimate_DH PF01488.15 EPS27450.1 - 0.033 14.2 0.0 0.058 13.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 EPS27450.1 - 0.04 13.9 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Het-C PF07217.6 EPS27450.1 - 0.17 10.0 0.0 0.25 9.4 0.0 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C VTC PF09359.5 EPS27451.1 - 3.3e-91 305.2 0.1 5.8e-91 304.4 0.0 1.4 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 EPS27451.1 - 7.5e-21 75.1 13.3 3.6e-12 46.6 0.4 4.5 2 2 2 4 4 4 2 SPX domain DUF202 PF02656.10 EPS27451.1 - 2.8e-10 40.2 3.8 2.8e-10 40.2 2.6 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Med10 PF09748.4 EPS27451.1 - 0.031 14.0 2.3 0.69 9.7 0.3 2.8 3 0 0 3 3 3 0 Transcription factor subunit Med10 of Mediator complex RTA1 PF04479.8 EPS27452.1 - 1.3e-60 204.7 11.5 1.3e-60 204.7 8.0 1.3 2 0 0 2 2 2 1 RTA1 like protein 7TMR-DISM_7TM PF07695.6 EPS27452.1 - 0.0047 16.6 20.6 0.025 14.2 5.6 2.5 1 1 0 2 2 2 2 7TM diverse intracellular signalling DUF4328 PF14219.1 EPS27452.1 - 6.8 5.9 8.6 0.81 8.9 0.8 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4328) Bac_rhamnosid PF05592.6 EPS27453.1 - 7.6e-32 110.1 0.1 2.5e-24 85.3 0.3 3.0 2 1 0 2 2 2 2 Bacterial alpha-L-rhamnosidase AA_permease_2 PF13520.1 EPS27455.1 - 3.5e-61 207.0 45.4 4.2e-61 206.7 31.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPS27455.1 - 7.4e-19 67.4 33.2 1e-18 66.9 23.0 1.0 1 0 0 1 1 1 1 Amino acid permease PSII_Ycf12 PF05969.6 EPS27456.1 - 0.012 15.2 1.1 0.034 13.7 0.7 1.8 1 0 0 1 1 1 0 Photosystem II complex subunit Ycf12 Sdh_cyt PF01127.17 EPS27456.1 - 0.015 15.1 0.5 0.015 15.1 0.4 2.7 2 1 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit PsiE PF06146.7 EPS27456.1 - 0.094 12.9 1.5 0.32 11.2 0.6 2.3 2 1 0 2 2 2 0 Phosphate-starvation-inducible E DUF3671 PF12420.3 EPS27456.1 - 0.14 12.1 4.7 0.2 11.6 1.1 2.6 2 1 0 2 2 2 0 Protein of unknown function TctB PF07331.6 EPS27456.1 - 7.3 6.2 9.7 1.3 8.6 3.1 2.2 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family MFS_1 PF07690.11 EPS27457.1 - 5.2e-37 127.3 40.4 5.7e-36 123.9 14.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS27457.1 - 3.2e-07 29.2 3.9 3.2e-07 29.2 2.7 1.9 1 1 1 2 2 2 1 Sugar (and other) transporter DUF791 PF05631.9 EPS27457.1 - 0.0015 17.3 1.6 0.0018 17.0 0.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF791) TRI12 PF06609.8 EPS27457.1 - 0.0024 16.1 1.2 0.0037 15.5 0.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Metallophos PF00149.23 EPS27458.1 - 2.6e-07 30.2 1.6 2e-06 27.3 1.1 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EPS27458.1 - 1.2e-06 28.4 0.0 4.3e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain CBFD_NFYB_HMF PF00808.18 EPS27460.1 - 4.4e-05 23.4 0.1 5.8e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-W PF15510.1 EPS27460.1 - 0.058 13.3 0.1 0.16 11.9 0.1 1.7 1 1 0 1 1 1 0 Centromere kinetochore component W NUDIX PF00293.23 EPS27461.1 - 3.9e-15 55.6 0.0 8.7e-15 54.5 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain DSBA PF01323.15 EPS27462.1 - 8.1e-36 123.3 0.0 4.8e-34 117.6 0.0 2.0 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 EPS27462.1 - 0.03 14.3 0.0 0.053 13.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin FMN_dh PF01070.13 EPS27463.1 - 3.3e-108 361.7 0.1 4e-108 361.4 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EPS27463.1 - 1.5e-21 75.9 0.0 9.9e-21 73.3 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.20 EPS27463.1 - 2.6e-06 26.5 0.1 0.0007 18.5 0.0 2.6 3 0 0 3 3 3 2 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EPS27463.1 - 3.3e-06 26.2 0.1 5.3e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 EPS27463.1 - 0.0091 15.2 0.0 0.14 11.3 0.0 2.2 2 0 0 2 2 2 1 Histidine biosynthesis protein ATP11 PF06644.6 EPS27463.1 - 0.045 13.2 0.0 0.067 12.6 0.0 1.2 1 0 0 1 1 1 0 ATP11 protein NMO PF03060.10 EPS27463.1 - 0.091 11.8 0.6 0.22 10.6 0.4 1.6 1 1 0 1 1 1 0 Nitronate monooxygenase DUF998 PF06197.8 EPS27464.1 - 0.047 12.9 4.7 0.16 11.2 3.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF998) DUF202 PF02656.10 EPS27464.1 - 0.053 13.7 7.9 0.34 11.1 5.5 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF202) DUF3215 PF11503.3 EPS27464.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3215) 6PF2K PF01591.13 EPS27465.1 - 4.9e-70 235.0 0.0 2.1e-49 167.5 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EPS27465.1 - 7.2e-31 107.4 0.0 1.3e-30 106.5 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EPS27465.1 - 2.6e-10 40.3 0.0 0.00011 22.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EPS27465.1 - 0.0012 19.6 0.0 0.0067 17.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 EPS27465.1 - 0.056 12.6 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MFS_1 PF07690.11 EPS27466.1 - 2e-13 49.8 25.7 3.2e-09 35.9 6.7 3.0 2 2 0 2 2 2 2 Major Facilitator Superfamily p450 PF00067.17 EPS27467.1 - 1.9e-16 59.6 0.1 2.8e-09 36.0 0.0 2.3 2 0 0 2 2 2 2 Cytochrome P450 Fer2 PF00111.22 EPS27468.1 - 2.9e-07 30.1 3.4 2.9e-07 30.1 2.4 1.7 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain FAD_binding_4 PF01565.18 EPS27469.1 - 7.5e-18 64.3 0.6 1.4e-17 63.5 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EPS27469.1 - 0.00018 21.3 0.0 0.00048 19.9 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like CaKB PF03185.10 EPS27469.1 - 0.045 13.1 0.1 0.067 12.5 0.0 1.2 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit Glyco_hydro_3 PF00933.16 EPS27470.1 - 2.5e-63 213.8 0.0 4e-63 213.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EPS27470.1 - 1.2e-54 185.2 0.0 1.7e-54 184.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EPS27470.1 - 2.9e-18 65.5 0.5 2.9e-18 65.5 0.3 2.7 2 0 0 2 2 2 1 Fibronectin type III-like domain HypD PF01924.11 EPS27470.1 - 0.097 11.3 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Hydrogenase formation hypA family Bin3 PF06859.7 EPS27471.1 - 1.4e-25 89.4 0.0 1.9e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_23 PF13489.1 EPS27471.1 - 1.7e-11 44.0 0.0 2.3e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS27471.1 - 3e-11 43.9 0.0 5.4e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPS27471.1 - 3.7e-09 36.3 0.0 4.7e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPS27471.1 - 8.3e-08 32.6 0.0 1.5e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPS27471.1 - 3.2e-06 27.5 0.0 6.3e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPS27471.1 - 2.5e-05 24.2 0.2 6.5e-05 22.9 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPS27471.1 - 5e-05 23.5 0.0 9.7e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPS27471.1 - 0.00013 21.4 0.0 0.00033 20.0 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase small domain PrmA PF06325.8 EPS27471.1 - 0.0025 16.9 0.0 0.0041 16.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FmrO PF07091.6 EPS27471.1 - 0.023 13.6 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_9 PF08003.6 EPS27471.1 - 0.13 10.9 0.0 0.16 10.6 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) Filament PF00038.16 EPS27472.1 - 0.0036 16.8 11.3 0.0047 16.4 7.8 1.1 1 0 0 1 1 1 1 Intermediate filament protein APG6 PF04111.7 EPS27472.1 - 0.0081 15.2 7.6 0.011 14.7 5.3 1.3 1 0 0 1 1 1 1 Autophagy protein Apg6 DUF4201 PF13870.1 EPS27472.1 - 0.011 15.1 11.3 0.017 14.6 7.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Macoilin PF09726.4 EPS27472.1 - 0.017 13.4 7.9 0.021 13.1 5.5 1.1 1 0 0 1 1 1 0 Transmembrane protein V_ATPase_I PF01496.14 EPS27472.1 - 0.028 12.3 4.1 0.033 12.0 2.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Rootletin PF15035.1 EPS27472.1 - 0.033 14.1 17.4 0.03 14.3 7.8 2.1 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion EMP24_GP25L PF01105.19 EPS27472.1 - 0.034 13.8 0.8 0.41 10.3 1.7 1.9 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Reo_sigmaC PF04582.7 EPS27472.1 - 0.051 12.7 0.6 0.067 12.3 0.4 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DUF4527 PF15030.1 EPS27472.1 - 0.06 12.6 1.8 0.12 11.7 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) DUF1664 PF07889.7 EPS27472.1 - 0.072 12.8 3.4 0.12 12.1 2.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) IncA PF04156.9 EPS27472.1 - 0.11 12.0 11.0 0.16 11.5 7.6 1.2 1 0 0 1 1 1 0 IncA protein GAS PF13851.1 EPS27472.1 - 0.15 11.2 9.7 0.25 10.4 6.7 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding BLOC1_2 PF10046.4 EPS27472.1 - 0.43 10.7 5.4 6.8 6.8 0.8 2.5 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF342 PF03961.8 EPS27472.1 - 0.57 8.5 5.8 0.77 8.1 4.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF972 PF06156.8 EPS27472.1 - 0.63 10.4 9.1 1.4 9.2 4.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Spc7 PF08317.6 EPS27472.1 - 1.4 7.5 10.0 2 6.9 6.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.4 EPS27472.1 - 1.9 8.3 15.0 0.49 10.2 8.4 1.5 2 0 0 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.4 EPS27472.1 - 2.1 7.2 13.6 3 6.6 9.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Mto2_bdg PF12808.2 EPS27472.1 - 2.2 8.4 19.3 0.47 10.6 0.7 3.6 2 1 1 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region FlaC_arch PF05377.6 EPS27472.1 - 5.1 7.0 6.8 8.5 6.3 1.3 2.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) FUSC PF04632.7 EPS27472.1 - 7.2 4.9 6.3 10 4.4 4.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family UPF0184 PF03670.8 EPS27472.1 - 8.7 6.6 12.0 20 5.4 5.9 2.7 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0184) Cauli_VI PF01693.11 EPS27473.1 - 7e-35 118.7 2.1 1.2e-16 60.4 0.1 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.19 EPS27473.1 - 2.3e-28 99.1 0.0 3.4e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 RNase H Na_H_Exchanger PF00999.16 EPS27474.1 - 6.2e-44 150.0 16.7 8e-44 149.6 11.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF1691 PF07950.6 EPS27474.1 - 0.014 15.2 2.0 0.017 15.0 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1691) Glyco_hydro_10 PF00331.15 EPS27475.1 - 9e-112 373.2 0.7 1e-111 373.0 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 DUF4339 PF14237.1 EPS27475.1 - 0.015 14.8 0.2 0.035 13.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4339) NTP_transf_3 PF12804.2 EPS27475.1 - 0.04 13.9 0.0 0.14 12.2 0.0 1.7 2 0 0 2 2 2 0 MobA-like NTP transferase domain GFO_IDH_MocA PF01408.17 EPS27476.1 - 1.6e-23 83.5 0.0 3.1e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 EPS27476.1 - 0.00053 20.2 0.0 0.0012 19.1 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain BC10 PF06726.7 EPS27478.1 - 4.3e-15 55.4 9.6 6.8e-15 54.8 6.7 1.3 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 Chs3p PF12271.3 EPS27480.1 - 5.2e-109 363.7 3.4 5.9e-109 363.5 2.3 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF998 PF06197.8 EPS27480.1 - 0.051 12.8 19.6 0.87 8.8 5.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF998) DUF973 PF06157.6 EPS27480.1 - 1.7 7.5 12.5 0.28 10.1 4.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF973) DUF1129 PF06570.6 EPS27480.1 - 1.8 7.8 5.7 0.73 9.1 1.8 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) DLH PF01738.13 EPS27481.1 - 2.5e-30 105.3 0.0 2.9e-30 105.1 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EPS27481.1 - 2.1e-08 34.0 0.0 2.7e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 EPS27481.1 - 0.0079 15.9 0.0 0.62 9.7 0.0 2.1 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2305 PF10230.4 EPS27481.1 - 0.05 13.0 0.0 0.065 12.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 EPS27481.1 - 0.057 13.2 0.0 5.5 6.7 0.0 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EPS27481.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) ERG4_ERG24 PF01222.12 EPS27483.1 - 5.7e-141 469.9 22.3 6.7e-141 469.7 15.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family zf-C3HC4 PF00097.20 EPS27484.1 - 2.2e-07 30.3 3.9 4.8e-07 29.3 2.7 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPS27484.1 - 3e-07 30.3 9.7 5e-07 29.6 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPS27484.1 - 3.5e-06 26.5 6.0 5.7e-06 25.9 4.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPS27484.1 - 3.9e-06 26.5 8.8 7.1e-06 25.7 6.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EPS27484.1 - 4.3e-06 26.4 5.1 3.9e-05 23.4 4.0 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EPS27484.1 - 0.0001 21.9 6.4 0.00021 20.9 4.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain GEMIN8 PF15348.1 EPS27484.1 - 0.014 15.4 1.4 0.014 15.4 0.9 2.0 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 zf-RING_UBOX PF13445.1 EPS27484.1 - 0.044 13.4 6.0 0.04 13.6 2.8 2.0 1 1 1 2 2 2 0 RING-type zinc-finger UCH PF00443.24 EPS27485.1 - 2.3e-49 167.9 0.0 4e-49 167.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPS27485.1 - 1.1e-19 71.0 0.0 1.6e-18 67.1 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase dCMP_cyt_deam_1 PF00383.17 EPS27486.1 - 1.3e-05 24.7 0.7 0.06 13.0 0.0 2.9 2 1 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region Cyclin PF08613.6 EPS27488.1 - 2.3e-29 102.7 0.0 4.3e-29 101.8 0.0 1.6 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EPS27488.1 - 1.2e-05 24.8 0.0 2.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Arm PF00514.18 EPS27489.1 - 7.7e-17 60.4 17.1 9.8e-05 22.0 0.1 10.0 13 0 0 13 13 13 4 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EPS27489.1 - 3.5e-07 30.4 7.7 0.57 10.5 0.0 7.0 7 2 1 8 8 8 2 HEAT repeats HEAT PF02985.17 EPS27489.1 - 0.0005 19.9 15.9 0.053 13.6 0.0 6.8 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.1 EPS27489.1 - 0.001 19.4 15.7 0.86 10.1 0.0 7.3 9 0 0 9 9 9 2 HEAT-like repeat V-ATPase_H_N PF03224.9 EPS27489.1 - 0.0071 15.5 0.0 0.12 11.4 0.0 2.9 3 1 1 4 4 4 1 V-ATPase subunit H Fructosamin_kin PF03881.9 EPS27490.1 - 2.5e-81 272.8 0.0 2.8e-81 272.6 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EPS27490.1 - 3.2e-11 43.4 0.7 6.9e-11 42.3 0.5 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EPS27490.1 - 0.19 10.3 0.0 0.27 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) GST_N_3 PF13417.1 EPS27491.1 - 2.4e-27 94.9 0.3 4.8e-27 93.9 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EPS27491.1 - 4.2e-19 68.3 0.2 1.9e-18 66.1 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EPS27491.1 - 1.1e-07 31.9 0.1 1.8e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EPS27491.1 - 2.6e-05 24.0 0.4 6.9e-05 22.6 0.3 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EPS27491.1 - 4.5e-05 23.3 0.0 0.00011 22.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EPS27491.1 - 0.0016 18.8 0.1 0.0029 18.0 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 EPS27491.1 - 0.12 12.4 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin Cyclin_N PF00134.18 EPS27492.1 - 7.4e-11 41.7 0.0 9.4e-10 38.1 0.0 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain CTP_transf_1 PF01148.15 EPS27493.1 - 7e-83 278.2 27.6 8.3e-83 277.9 19.1 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF3636 PF12331.3 EPS27494.1 - 1e-50 171.1 0.0 1.8e-50 170.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) IncA PF04156.9 EPS27494.1 - 0.0058 16.2 7.1 0.01 15.4 4.9 1.5 1 0 0 1 1 1 1 IncA protein Ribosomal_S24e PF01282.14 EPS27494.1 - 0.057 13.2 2.8 0.094 12.5 0.6 2.2 3 0 0 3 3 3 0 Ribosomal protein S24e Atg14 PF10186.4 EPS27494.1 - 0.22 10.4 6.8 0.054 12.4 2.3 1.6 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 PcfJ PF14284.1 EPS27494.1 - 0.23 10.9 5.8 1.1 8.6 0.0 2.5 2 0 0 2 2 2 0 PcfJ-like protein DUF4559 PF15112.1 EPS27494.1 - 1 8.4 5.8 1.8 7.6 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Mod_r PF07200.8 EPS27494.1 - 1.2 9.0 10.2 13 5.6 0.1 2.4 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein APG6 PF04111.7 EPS27494.1 - 1.8 7.5 8.6 3.2 6.7 6.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 S4 PF01479.20 EPS27495.1 - 1.5e-15 56.3 0.7 3.1e-15 55.3 0.0 1.9 2 0 0 2 2 2 1 S4 domain HBS1_N PF08938.5 EPS27495.1 - 0.035 14.2 2.3 7.2 6.8 0.0 2.6 3 0 0 3 3 3 0 HBS1 N-terminus Musclin PF11037.3 EPS27495.1 - 0.037 13.6 0.5 0.07 12.7 0.4 1.5 1 0 0 1 1 1 0 Insulin-resistance promoting peptide in skeletal muscle S4_2 PF13275.1 EPS27495.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 S4 domain NPIP PF06409.6 EPS27496.1 - 0.018 13.7 0.1 0.04 12.6 0.1 1.5 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) DUF2939 PF11159.3 EPS27496.1 - 0.11 12.6 1.2 0.23 11.6 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2939) E1_dh PF00676.15 EPS27497.1 - 1.5e-113 378.4 0.4 1.9e-113 378.1 0.3 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EPS27497.1 - 0.00043 19.3 0.0 0.00077 18.4 0.0 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase PH_10 PF15411.1 EPS27500.1 - 3e-23 82.1 0.0 5.2e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain VWA_3 PF13768.1 EPS27500.1 - 1e-10 41.5 0.1 5.6e-10 39.1 0.0 2.3 2 1 0 2 2 2 1 von Willebrand factor type A domain zf-RING_2 PF13639.1 EPS27500.1 - 3.6e-08 33.0 6.2 7.3e-08 32.1 4.3 1.6 1 0 0 1 1 1 1 Ring finger domain VWA PF00092.23 EPS27500.1 - 5.8e-08 32.6 0.0 1.1e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-C3HC4_3 PF13920.1 EPS27500.1 - 0.0006 19.4 2.1 0.0011 18.5 1.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPS27500.1 - 0.00094 18.8 5.5 0.0017 18.0 3.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EPS27500.1 - 0.0024 17.9 2.1 0.0052 16.8 1.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EPS27500.1 - 0.025 14.5 5.0 0.048 13.7 3.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPS27500.1 - 0.03 13.9 5.3 0.063 12.9 3.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1147 PF06615.6 EPS27500.1 - 0.047 13.5 0.6 0.098 12.5 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) PH_5 PF15405.1 EPS27500.1 - 0.053 13.4 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain zf-RING-like PF08746.6 EPS27500.1 - 0.82 9.7 4.9 1.6 8.8 3.4 1.5 1 0 0 1 1 1 0 RING-like domain Peptidase_M48 PF01435.13 EPS27501.1 - 6.5e-35 120.7 0.0 8.6e-35 120.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Cpn60_TCP1 PF00118.19 EPS27502.1 - 1.1e-135 452.9 2.4 1.3e-135 452.7 1.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ribosomal_L12 PF00542.14 EPS27503.1 - 2.1e-19 69.2 8.2 1.5e-18 66.5 4.2 2.3 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Bac_DNA_binding PF00216.16 EPS27503.1 - 0.062 13.3 0.5 0.13 12.3 0.4 1.5 1 0 0 1 1 1 0 Bacterial DNA-binding protein TPR_8 PF13181.1 EPS27504.1 - 2.5 8.1 5.0 11 6.0 0.4 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Velvet PF11754.3 EPS27505.1 - 5.7e-62 208.9 0.0 7.5e-62 208.5 0.0 1.1 1 0 0 1 1 1 1 Velvet factor Cdc6_C PF09079.6 EPS27505.1 - 0.08 12.6 0.1 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 CDC6, C terminal NUFIP2 PF15293.1 EPS27507.1 - 0.26 9.9 0.0 0.44 9.2 0.0 1.2 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 2 SYF2 PF08231.7 EPS27508.1 - 6.5e-55 185.4 14.9 6.5e-55 185.4 10.3 1.9 2 0 0 2 2 2 1 SYF2 splicing factor NAD_binding_10 PF13460.1 EPS27509.1 - 1.3e-13 51.3 0.0 2.4e-12 47.2 0.0 2.3 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPS27509.1 - 2.2e-07 30.5 0.0 4.2e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPS27509.1 - 4.3e-06 25.6 0.0 1.2e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EPS27509.1 - 0.00028 20.8 0.0 0.00054 19.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EPS27509.1 - 0.011 14.6 0.0 0.14 10.9 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain NAD_binding_4 PF07993.7 EPS27509.1 - 0.025 13.4 0.0 1.6 7.5 0.0 2.3 2 0 0 2 2 2 0 Male sterility protein 3HCDH_N PF02737.13 EPS27509.1 - 0.061 12.9 0.0 3.3 7.3 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YEATS PF03366.11 EPS27510.1 - 4e-35 119.3 0.9 6.5e-35 118.7 0.6 1.3 1 0 0 1 1 1 1 YEATS family IDO PF01231.13 EPS27511.1 - 1.2e-155 518.1 0.0 1.4e-155 517.9 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.6 EPS27511.1 - 0.0085 14.6 0.0 0.024 13.1 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1864) Aminotran_5 PF00266.14 EPS27512.1 - 1.9e-08 33.4 0.0 1.8e-06 26.9 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EPS27512.1 - 0.02 13.9 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Fungal_trans PF04082.13 EPS27513.1 - 9.4e-13 47.6 0.1 2.8e-12 46.0 0.1 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS27513.1 - 1.3e-08 34.6 10.5 2.4e-08 33.7 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain COX7a PF02238.10 EPS27514.1 - 0.085 12.5 0.6 0.19 11.4 0.4 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase subunit VIIa PI-PLC-X PF00388.14 EPS27516.1 - 0.008 15.5 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Ins_P5_2-kin PF06090.7 EPS27517.1 - 4.7e-68 229.5 0.0 5.6e-68 229.2 0.0 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Oxidored_molyb PF00174.14 EPS27518.1 - 6.3e-48 162.3 0.0 1.1e-47 161.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EPS27518.1 - 1.4e-38 131.5 0.3 3e-38 130.4 0.2 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain NAD_binding_1 PF00175.16 EPS27518.1 - 1.7e-21 76.8 0.0 1.1e-20 74.1 0.0 2.5 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EPS27518.1 - 3.3e-20 72.0 0.0 7.2e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 EPS27518.1 - 1.4e-17 63.2 0.1 4.3e-17 61.6 0.1 1.9 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 EPS27518.1 - 0.0035 17.2 0.7 0.21 11.4 0.0 3.3 2 1 0 3 3 3 1 Ferric reductase NAD binding domain LMBR1 PF04791.11 EPS27518.1 - 6 5.3 4.0 11 4.5 2.8 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Molybdopterin PF00384.17 EPS27519.1 - 9.8e-68 228.8 0.0 1.3e-67 228.4 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin oxidoreductase Molydop_binding PF01568.16 EPS27519.1 - 6.1e-26 90.3 0.0 1.3e-25 89.3 0.0 1.6 1 0 0 1 1 1 1 Molydopterin dinucleotide binding domain Molybdop_Fe4S4 PF04879.11 EPS27519.1 - 4.4e-12 45.6 1.1 8.1e-12 44.7 0.1 2.0 2 0 0 2 2 2 1 Molybdopterin oxidoreductase Fe4S4 domain NTP_transf_3 PF12804.2 EPS27520.1 - 1e-19 71.1 0.0 2.1e-19 70.1 0.0 1.5 1 1 0 1 1 1 1 MobA-like NTP transferase domain MoeA_N PF03453.12 EPS27521.1 - 7.9e-30 103.3 0.0 1.1e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.19 EPS27521.1 - 8.4e-27 93.3 0.0 1.3e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain NUDIX PF00293.23 EPS27522.1 - 3.8e-20 71.9 0.1 4.4e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 EPS27522.1 - 0.065 12.6 0.0 0.096 12.1 0.0 1.3 1 1 0 1 1 1 0 NUDIX domain Tub_2 PF04525.7 EPS27523.1 - 0.00035 20.0 0.0 0.0013 18.1 0.0 1.9 1 1 0 1 1 1 1 Tubby C 2 ParBc PF02195.13 EPS27523.1 - 0.055 13.5 0.0 3.4 7.8 0.1 2.3 1 1 1 2 2 2 0 ParB-like nuclease domain Acetyltransf_3 PF13302.1 EPS27525.1 - 1.1e-31 109.8 0.0 1.4e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EPS27525.1 - 1.4e-06 28.2 0.0 3.6e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPS27525.1 - 3.1e-06 27.1 0.0 5.6e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EPS27525.1 - 0.02 14.8 0.0 0.051 13.5 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPS27525.1 - 0.1 12.3 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein WES_acyltransf PF03007.11 EPS27526.1 - 0.2 11.2 4.0 0.26 10.8 2.8 1.2 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Polysacc_deac_1 PF01522.16 EPS27527.1 - 5.9e-24 84.0 0.1 9.4e-24 83.4 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Novirhabdo_Nv PF05554.6 EPS27527.1 - 0.01 15.3 0.1 0.058 12.9 0.0 2.1 2 0 0 2 2 2 1 Viral hemorrhagic septicemia virus non-virion protein DUF1682 PF07946.9 EPS27528.1 - 1.7e-110 368.8 1.7 2.1e-110 368.5 1.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Phage_Gp23 PF10669.4 EPS27528.1 - 1 9.4 8.7 1.8 8.7 6.1 1.4 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) DUF2404 PF10296.4 EPS27529.1 - 0.00021 21.3 0.0 0.00069 19.6 0.0 1.9 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) DUF3635 PF12330.3 EPS27531.1 - 1.7e-05 24.8 0.4 5.7e-05 23.1 0.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3635) Med20 PF08612.6 EPS27532.1 - 4e-78 261.6 0.0 4.7e-78 261.4 0.0 1.0 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Med3 PF11593.3 EPS27532.1 - 4.8 6.3 6.2 6.7 5.8 4.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal EF-hand_1 PF00036.27 EPS27533.1 - 3.1e-41 135.5 11.5 1.1e-09 36.9 0.6 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EPS27533.1 - 9.2e-37 125.0 5.9 6.4e-20 71.0 1.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EPS27533.1 - 1.5e-34 117.3 11.8 6.8e-16 57.6 0.5 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EPS27533.1 - 1.5e-30 102.3 6.8 3.4e-09 35.8 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EPS27533.1 - 1.8e-26 90.2 7.7 1.9e-06 26.9 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EPS27533.1 - 1.2e-15 57.0 0.3 2.2e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EPS27533.1 - 5.1e-10 39.0 1.5 0.00063 19.4 0.2 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EPS27533.1 - 1.6e-08 34.5 0.0 0.0038 17.2 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 EPS27533.1 - 3.2e-08 33.0 0.1 0.022 14.3 0.0 3.2 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 EPS27533.1 - 5.8e-07 29.3 2.4 4.5e-06 26.5 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 EPS27533.1 - 0.00015 21.5 0.3 0.32 10.7 0.0 2.2 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 EPS27533.1 - 0.0004 19.9 0.1 0.064 12.8 0.1 2.7 1 1 0 1 1 1 1 Caleosin related protein Tenui_NCP PF04876.7 EPS27533.1 - 0.0025 17.3 0.1 0.13 11.8 0.0 2.3 1 1 1 2 2 2 1 Tenuivirus major non-capsid protein RNA_pol_Rpb4 PF03874.11 EPS27533.1 - 0.0027 17.6 0.7 1.3 9.0 0.0 2.6 3 0 0 3 3 3 2 RNA polymerase Rpb4 Toprim_2 PF13155.1 EPS27533.1 - 0.0059 16.9 1.4 1.8 8.9 0.0 2.5 1 1 1 2 2 2 2 Toprim-like DUF3349 PF11829.3 EPS27533.1 - 0.025 14.9 0.4 8.4 6.8 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) EF-hand_10 PF14788.1 EPS27533.1 - 0.14 11.8 2.4 0.84 9.3 0.1 3.1 1 1 3 4 4 4 0 EF hand RloB PF13707.1 EPS27533.1 - 0.28 10.8 4.1 0.59 9.7 0.3 2.3 1 1 1 2 2 2 0 RloB-like protein PB1 PF00564.19 EPS27533.1 - 0.43 10.2 2.8 35 4.1 0.0 3.3 2 1 1 3 3 3 0 PB1 domain SNARE PF05739.14 EPS27534.1 - 4.5e-17 61.4 3.6 4.5e-17 61.4 2.5 2.4 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EPS27534.1 - 1.5e-12 47.5 0.1 1.5e-12 47.5 0.0 2.5 2 1 0 2 2 2 1 Syntaxin DUF3357 PF11837.3 EPS27534.1 - 0.0013 18.5 0.1 0.0027 17.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3357) Syntaxin_2 PF14523.1 EPS27534.1 - 0.013 15.5 9.1 0.12 12.4 0.0 3.3 2 2 1 3 3 3 0 Syntaxin-like protein MCPsignal PF00015.16 EPS27534.1 - 0.017 14.6 10.1 0.019 14.5 1.9 2.6 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain ODV-E18 PF10717.4 EPS27534.1 - 0.088 12.2 0.0 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF2019 PF09450.5 EPS27534.1 - 0.11 12.3 1.8 0.23 11.3 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2019) FliD_C PF07195.7 EPS27534.1 - 0.32 10.2 6.1 1.4 8.2 0.1 2.2 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 C-terminus ATG16 PF08614.6 EPS27534.1 - 3.5 7.3 10.5 0.64 9.8 2.3 2.6 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) CTD_bind PF04818.8 EPS27535.1 - 5.3e-21 74.6 0.1 1.4e-20 73.2 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Clathrin_lg_ch PF01086.12 EPS27536.1 - 1.5e-73 247.4 4.9 1.7e-73 247.3 3.4 1.0 1 0 0 1 1 1 1 Clathrin light chain CDC37_N PF03234.9 EPS27537.1 - 3.4e-60 203.3 6.1 3.4e-60 203.3 4.2 2.6 2 1 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 EPS27537.1 - 1.8e-49 167.5 0.0 5.4e-49 166.0 0.0 1.8 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 EPS27537.1 - 1.9e-28 98.2 4.0 2.2e-28 98.0 1.2 2.3 2 0 0 2 2 2 1 Cdc37 C terminal domain MecA_N PF05223.6 EPS27537.1 - 0.0077 16.2 0.8 0.0077 16.2 0.6 2.5 3 0 0 3 3 3 1 NTF2-like N-terminal transpeptidase domain CesA PF11439.3 EPS27537.1 - 0.055 13.3 0.2 0.28 11.1 0.0 2.3 2 0 0 2 2 2 0 Type III secretion system filament chaperone CesA ABC_membrane PF00664.18 EPS27538.1 - 1.5e-46 159.0 10.6 2.1e-46 158.5 7.4 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EPS27538.1 - 1.2e-35 122.7 0.0 2.4e-35 121.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EPS27538.1 - 1.7e-05 24.1 0.0 0.0009 18.5 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EPS27538.1 - 0.0001 22.3 0.4 0.14 12.0 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EPS27538.1 - 0.0029 17.0 0.1 0.0077 15.7 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_ATPase PF09818.4 EPS27538.1 - 0.026 13.1 0.9 0.062 11.8 0.1 1.8 2 0 0 2 2 2 0 Predicted ATPase of the ABC class SbcCD_C PF13558.1 EPS27538.1 - 0.029 14.2 0.6 0.22 11.4 0.4 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 EPS27538.1 - 0.043 13.9 0.3 0.28 11.3 0.2 2.2 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EPS27538.1 - 0.052 13.5 0.7 0.26 11.2 0.5 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 EPS27538.1 - 0.084 13.1 0.2 0.24 11.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain IstB_IS21 PF01695.12 EPS27538.1 - 0.1 12.0 0.1 0.74 9.2 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_17 PF13207.1 EPS27538.1 - 0.1 13.4 0.0 0.22 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EPS27538.1 - 0.16 11.3 0.3 0.86 8.9 0.2 2.0 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EPS27538.1 - 0.17 11.0 0.0 0.35 10.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Yip1 PF04893.12 EPS27538.1 - 2.8 7.3 14.1 2.7 7.4 1.0 3.0 3 0 0 3 3 3 0 Yip1 domain APH PF01636.18 EPS27539.1 - 7.8e-09 35.6 0.0 0.0013 18.5 0.0 2.4 1 1 0 2 2 2 2 Phosphotransferase enzyme family GFA PF04828.9 EPS27540.1 - 3.3e-23 81.4 0.0 4.3e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Zn_ribbon_recom PF13408.1 EPS27540.1 - 0.11 12.8 2.2 4.1 7.7 0.0 2.4 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-NADH-PPase PF09297.6 EPS27540.1 - 0.33 10.5 0.3 0.33 10.5 0.2 2.6 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Nucleoside_tran PF01733.13 EPS27541.1 - 8.6e-48 163.0 17.6 1.7e-45 155.5 12.2 2.3 1 1 0 1 1 1 1 Nucleoside transporter MFS_1 PF07690.11 EPS27541.1 - 0.00025 19.8 41.9 0.066 11.9 6.9 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Scs3p PF10261.4 EPS27541.1 - 0.6 9.1 0.0 0.6 9.1 0.0 2.5 3 0 0 3 3 3 0 Inositol phospholipid synthesis and fat-storage-inducing TM DUF1049 PF06305.6 EPS27541.1 - 0.77 9.2 0.0 0.77 9.2 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1049) Glyco_hydro_47 PF01532.15 EPS27542.1 - 4.2e-171 569.5 0.0 4.8e-171 569.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF3328 PF11807.3 EPS27542.1 - 0.031 13.9 0.8 0.055 13.1 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) LSM PF01423.17 EPS27543.1 - 4.2e-19 67.8 0.0 4.7e-19 67.6 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EPS27543.1 - 0.00045 20.0 0.0 0.00054 19.8 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain IceA2 PF05862.6 EPS27543.1 - 0.077 12.7 0.3 0.15 11.7 0.1 1.6 1 1 0 1 1 1 0 Helicobacter pylori IceA2 protein Rad60-SLD PF11976.3 EPS27544.1 - 3.9e-21 74.5 0.1 2.1e-19 68.9 0.0 2.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EPS27544.1 - 6.7e-06 25.4 0.1 3.6e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin family Trm112p PF03966.11 EPS27545.1 - 1.1e-14 54.5 0.0 1.3e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Trm112p-like protein Zn_ribbon_recom PF13408.1 EPS27545.1 - 0.022 14.9 0.2 0.042 14.1 0.1 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain N-SET PF11764.3 EPS27546.1 - 1.1e-48 165.2 0.4 2.4e-48 164.1 0.3 1.6 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.3 EPS27546.1 - 5.6e-25 86.4 0.7 1e-24 85.5 0.5 1.5 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated SET PF00856.23 EPS27546.1 - 7.6e-24 84.8 0.2 7.6e-24 84.8 0.1 2.6 2 2 0 2 2 2 1 SET domain RRM_1 PF00076.17 EPS27546.1 - 0.001 18.6 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SIS PF01380.17 EPS27547.1 - 2e-56 189.1 0.0 1.8e-29 101.9 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 EPS27547.1 - 8.3e-28 97.1 0.1 5e-19 68.2 0.0 2.3 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EPS27547.1 - 3.6e-19 69.0 0.0 7.2e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EPS27547.1 - 3.4e-12 46.1 0.0 7.6e-12 45.0 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EPS27547.1 - 8.6e-07 27.9 0.0 1.5e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 EPS27547.1 - 0.1 12.3 0.0 0.3 10.8 0.0 1.8 1 0 0 1 1 1 0 SIS domain DMRL_synthase PF00885.14 EPS27548.1 - 8.1e-45 152.0 0.1 3.4e-25 88.3 0.0 2.1 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase Proteasome PF00227.21 EPS27549.1 - 1.4e-46 158.2 0.9 1.3e-32 112.5 0.0 2.7 2 1 0 3 3 3 2 Proteasome subunit Proteasome_A_N PF10584.4 EPS27549.1 - 8.4e-12 44.1 0.9 1e-11 43.9 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Elf1 PF05129.8 EPS27550.1 - 0.023 14.3 0.2 0.041 13.5 0.2 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zf-Mss51 PF13824.1 EPS27550.1 - 0.057 13.2 0.4 0.17 11.7 0.3 1.9 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF2387 PF09526.5 EPS27550.1 - 0.1 12.5 0.3 0.29 11.0 0.2 1.8 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) Iso_dh PF00180.15 EPS27551.1 - 2.4e-84 283.2 0.0 2.9e-84 282.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase CP12 PF02672.10 EPS27552.1 - 0.47 10.9 3.6 0.61 10.5 2.5 1.4 1 0 0 1 1 1 0 CP12 domain MDMPI_N PF11716.3 EPS27552.1 - 1.5 9.2 6.4 28 5.1 4.4 2.0 1 1 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain WBS_methylT PF12589.3 EPS27553.1 - 1.4e-17 63.9 2.9 2.4e-17 63.1 2.0 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EPS27553.1 - 1.1e-10 41.8 0.0 2.2e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPS27553.1 - 6.3e-08 32.9 0.0 1.3e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPS27553.1 - 9.2e-06 25.3 0.0 1.4e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPS27553.1 - 6.4e-05 22.9 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPS27553.1 - 7.9e-05 23.0 0.0 0.00021 21.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS27553.1 - 0.00014 22.3 0.0 0.00026 21.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPS27553.1 - 0.00016 21.4 0.0 0.00022 20.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EPS27553.1 - 0.00092 18.8 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 EPS27553.1 - 0.0037 16.3 0.0 0.015 14.4 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EPS27553.1 - 0.057 12.4 0.0 0.63 9.0 0.0 2.0 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Erv26 PF04148.8 EPS27554.1 - 3.2e-94 314.1 3.1 3.7e-94 314.0 2.1 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 Cytochrom_C_asm PF01578.15 EPS27554.1 - 0.0023 17.4 0.5 0.004 16.7 0.0 1.7 2 0 0 2 2 2 1 Cytochrome C assembly protein DUF3377 PF11857.3 EPS27554.1 - 0.12 11.9 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) RhoGAP PF00620.22 EPS27555.1 - 3.3e-41 140.4 0.1 6.3e-41 139.5 0.1 1.4 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 EPS27555.1 - 1.9e-13 50.4 0.0 4e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EPS27555.1 - 1.1e-06 28.7 0.0 2.6e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain DUF3450 PF11932.3 EPS27555.1 - 0.0013 18.0 0.8 0.0024 17.1 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) PH_8 PF15409.1 EPS27555.1 - 0.0063 16.5 0.0 0.15 12.1 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain DUF386 PF04074.7 EPS27555.1 - 0.18 11.2 0.0 0.39 10.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF386) MDM31_MDM32 PF08118.6 EPS27556.1 - 3.5e-196 652.5 0.0 4.1e-196 652.3 0.0 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Ribosomal_60s PF00428.14 EPS27556.1 - 0.022 15.1 1.1 0.058 13.7 0.8 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Peptidase_M61 PF05299.7 EPS27556.1 - 0.14 12.1 0.0 5.7 6.9 0.0 2.4 2 0 0 2 2 2 0 M61 glycyl aminopeptidase KH_1 PF00013.24 EPS27557.1 - 0.00019 21.0 1.8 0.00038 20.0 1.2 1.5 1 0 0 1 1 1 1 KH domain Proteasome PF00227.21 EPS27558.1 - 6.2e-33 113.6 0.1 2.3e-32 111.8 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit HCNGP PF07818.8 EPS27559.1 - 4.9e-32 109.8 0.1 6.6e-32 109.4 0.1 1.1 1 0 0 1 1 1 1 HCNGP-like protein Clathrin_H_link PF13838.1 EPS27559.1 - 0.14 12.0 0.0 4.4 7.2 0.0 2.3 2 0 0 2 2 2 0 Clathrin-H-link Proteasome PF00227.21 EPS27560.1 - 8e-27 93.7 0.0 9.4e-27 93.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit FAA_hydrolase PF01557.13 EPS27561.1 - 2.7e-60 203.5 0.0 3.4e-60 203.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family HSP20 PF00011.16 EPS27562.1 - 3.9e-16 58.7 0.4 3.4e-12 46.1 0.1 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family Autophagy_act_C PF03987.10 EPS27564.1 - 3.2e-11 43.2 0.2 5.5e-11 42.4 0.1 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain DUF3300 PF11737.3 EPS27564.1 - 0.073 12.3 0.2 0.098 11.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3300) RRM_5 PF13893.1 EPS27565.1 - 1.1e-09 38.0 0.2 1.5e-09 37.5 0.2 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPS27565.1 - 1.6e-09 37.2 0.1 3.9e-09 35.9 0.1 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS27565.1 - 1e-06 28.6 0.0 1.7e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EPS27566.1 - 4e-21 74.0 12.4 1.4e-08 34.3 0.1 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat Rax2 PF12768.2 EPS27566.1 - 0.00023 20.4 0.1 0.0036 16.5 0.0 2.3 2 0 0 2 2 2 1 Cortical protein marker for cell polarity Pkinase PF00069.20 EPS27567.1 - 1.1e-64 218.0 0.0 1.4e-64 217.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS27567.1 - 7.9e-29 100.5 0.0 1.1e-28 99.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EPS27567.1 - 8.7e-07 28.2 0.0 1.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EPS27567.1 - 0.00043 19.3 0.0 0.00059 18.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EPS27567.1 - 0.0026 17.5 0.2 0.01 15.5 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EPS27567.1 - 0.003 16.9 0.1 0.0043 16.4 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pox_ser-thr_kin PF05445.6 EPS27567.1 - 0.013 14.3 0.4 0.017 13.9 0.3 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.6 EPS27567.1 - 0.035 12.9 0.2 0.087 11.6 0.1 1.6 1 1 1 2 2 2 0 Seadornavirus VP7 Fungal_trans PF04082.13 EPS27569.1 - 5.6e-23 81.1 4.2 5.6e-23 81.1 2.9 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS27569.1 - 3.1e-08 33.3 5.5 6.7e-08 32.3 3.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 EPS27570.1 - 2.9e-36 125.0 23.7 6.3e-22 77.7 3.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EPS27570.1 - 1.1e-18 67.1 35.9 5.6e-13 48.3 9.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Melibiase PF02065.13 EPS27571.1 - 7.5e-38 130.2 0.0 1.4e-23 83.2 0.0 2.1 1 1 1 2 2 2 2 Melibiase CBM_1 PF00734.13 EPS27571.1 - 1.1e-12 47.4 13.6 1.1e-12 47.4 9.4 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain Lipase_3 PF01764.20 EPS27572.1 - 4.3e-29 100.9 0.0 2.1e-28 98.6 0.0 1.9 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EPS27572.1 - 0.0013 18.4 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPS27572.1 - 0.0076 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EPS27572.1 - 0.0086 15.6 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF2974 PF11187.3 EPS27572.1 - 0.015 14.6 0.0 0.23 10.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) DUF676 PF05057.9 EPS27572.1 - 0.05 12.8 0.0 0.073 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) UPF0227 PF05728.7 EPS27572.1 - 0.052 13.2 0.0 0.084 12.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Esterase PF00756.15 EPS27572.1 - 0.083 12.3 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.15 EPS27572.1 - 0.091 12.2 0.6 0.65 9.5 0.0 2.4 3 0 0 3 3 3 0 alpha/beta hydrolase fold WW PF00397.21 EPS27573.1 - 5.9e-09 35.6 0.6 1.5e-08 34.3 0.4 1.8 1 0 0 1 1 1 1 WW domain Serinc PF03348.10 EPS27573.1 - 1.5 7.4 2.5 2.3 6.8 1.7 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Fungal_trans_2 PF11951.3 EPS27574.1 - 1.8e-17 63.0 7.1 2.6e-17 62.5 4.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS27574.1 - 7.5e-09 35.3 7.7 1.2e-08 34.7 5.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4463 PF14703.1 EPS27574.1 - 0.073 13.5 0.1 5.2 7.6 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) Ecm29 PF13001.2 EPS27576.1 - 1.9e-159 531.3 0.0 8.6e-159 529.2 0.0 2.2 2 1 0 2 2 2 1 Proteasome stabiliser HEAT PF02985.17 EPS27576.1 - 5.9e-09 35.2 7.2 0.42 10.8 0.0 9.9 10 0 0 10 10 10 2 HEAT repeat Vac14_Fab1_bd PF12755.2 EPS27576.1 - 7.6e-07 29.4 0.0 0.008 16.5 0.1 5.0 5 2 1 6 6 6 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EPS27576.1 - 0.00029 19.3 0.4 1.9 6.7 0.0 3.8 3 0 0 3 3 3 3 Adaptin N terminal region SNF2_N PF00176.18 EPS27577.1 - 1.6e-56 191.3 0.0 1.1e-55 188.5 0.0 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.1 EPS27577.1 - 4e-09 36.0 6.1 9.4e-09 34.8 4.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPS27577.1 - 1.6e-08 34.0 8.8 3.8e-08 32.8 6.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPS27577.1 - 7.9e-08 32.0 10.0 1.9e-07 30.8 6.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EPS27577.1 - 3e-05 23.9 10.2 7.8e-05 22.6 7.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPS27577.1 - 3.3e-05 23.4 9.0 8.1e-05 22.2 6.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EPS27577.1 - 0.00019 21.4 6.7 0.00051 20.0 4.7 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger Baculo_IE-1 PF05290.6 EPS27577.1 - 0.0014 18.3 1.1 0.0041 16.8 0.8 1.8 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.1 EPS27577.1 - 0.0051 16.3 3.7 0.013 14.9 2.3 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Helicase_C PF00271.26 EPS27577.1 - 0.0053 16.5 0.0 0.017 14.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.1 EPS27577.1 - 0.038 13.7 4.3 0.15 11.8 3.0 2.1 1 1 0 1 1 1 0 RING-type zinc-finger zf-P11 PF03854.9 EPS27577.1 - 0.11 11.9 9.4 0.25 10.8 6.5 1.6 1 0 0 1 1 1 0 P-11 zinc finger zf-C3HC4_4 PF15227.1 EPS27577.1 - 0.11 12.3 8.5 0.24 11.2 5.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EPS27577.1 - 0.68 9.5 8.2 2 8.0 5.7 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DZR PF12773.2 EPS27577.1 - 9.6 6.1 7.1 19 5.1 2.8 2.5 2 0 0 2 2 2 0 Double zinc ribbon PNGaseA PF12222.3 EPS27578.1 - 2.1e-161 537.5 4.2 2.5e-161 537.3 2.9 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A DUF1640 PF07798.6 EPS27579.1 - 3.4e-64 216.1 4.8 4.2e-64 215.8 3.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Metal_resist PF13801.1 EPS27579.1 - 0.062 13.2 2.6 0.16 11.9 1.8 1.7 1 0 0 1 1 1 0 Heavy-metal resistance PMM PF03332.8 EPS27580.1 - 1e-103 345.6 0.1 1.2e-103 345.4 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 EPS27580.1 - 0.0048 16.4 0.0 0.023 14.2 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TMPIT PF07851.8 EPS27580.1 - 0.013 14.5 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein S6PP PF05116.8 EPS27580.1 - 0.022 14.0 0.0 1.5 8.0 0.0 2.1 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase DUF2608 PF11019.3 EPS27580.1 - 0.14 11.1 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) DnaJ PF00226.26 EPS27581.1 - 3.2e-21 74.8 0.8 5e-21 74.2 0.6 1.3 1 0 0 1 1 1 1 DnaJ domain Gly-zipper_OmpA PF13436.1 EPS27581.1 - 6.6e-05 22.5 0.2 0.00013 21.5 0.1 1.5 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain Bacteriocin_IIc PF10439.4 EPS27581.1 - 0.013 15.6 3.0 0.019 15.0 2.0 1.3 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DUF456 PF04306.8 EPS27581.1 - 0.015 15.3 1.0 0.021 14.8 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Gly-zipper_Omp PF13488.1 EPS27581.1 - 0.69 9.5 12.7 1.3 8.7 8.8 1.4 1 0 0 1 1 1 0 Glycine zipper Gly-zipper_YMGG PF13441.1 EPS27581.1 - 0.76 9.3 14.8 1.3 8.5 10.0 1.5 1 1 0 1 1 1 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.10 EPS27581.1 - 1.2 8.8 15.5 2.9 7.6 10.7 1.6 1 1 0 1 1 1 0 Glycine zipper 2TM domain DnaJ PF00226.26 EPS27583.1 - 3.3e-08 33.1 3.0 1.2e-07 31.3 2.1 1.9 1 1 0 1 1 1 1 DnaJ domain PRA1 PF03208.14 EPS27584.1 - 1.7e-34 118.3 4.3 2.6e-34 117.7 3.0 1.2 1 0 0 1 1 1 1 PRA1 family protein BCD PF15461.1 EPS27584.1 - 0.16 11.3 3.2 0.054 12.8 0.4 1.4 2 0 0 2 2 2 0 Beta-carotene 15,15'-dioxygenase PAT1 PF09770.4 EPS27584.1 - 3.7 5.6 10.1 4.7 5.3 7.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Frag1 PF10277.4 EPS27585.1 - 9e-43 146.2 9.6 1e-42 146.0 6.7 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF3353 PF11833.3 EPS27585.1 - 0.063 12.7 0.1 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) DUF4407 PF14362.1 EPS27585.1 - 0.4 9.5 3.3 0.74 8.7 2.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF373 PF04123.8 EPS27585.1 - 1.8 7.4 7.3 0.47 9.4 3.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Y_phosphatase3 PF13350.1 EPS27588.1 - 1.9e-30 106.3 0.9 9.5e-29 100.7 0.6 2.1 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 EPS27588.1 - 1.6e-07 30.8 0.0 1.1e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EPS27588.1 - 4.7e-06 26.6 0.1 1.1e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 EPS27588.1 - 0.0041 16.4 0.0 0.0062 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EPS27588.1 - 0.0079 15.7 0.0 0.039 13.5 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Myotub-related PF06602.9 EPS27588.1 - 0.046 12.4 0.1 0.17 10.6 0.0 1.7 2 0 0 2 2 2 0 Myotubularin-like phosphatase domain Glyco_hydro_35 PF01301.14 EPS27589.1 - 2e-78 263.9 3.6 2.9e-78 263.4 2.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 EPS27589.1 - 1.2e-56 191.0 2.6 2e-56 190.2 1.8 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 EPS27589.1 - 5.7e-49 165.0 2.0 1.8e-24 86.1 0.9 3.2 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 EPS27589.1 - 1.3e-23 82.1 0.1 3.1e-23 80.9 0.0 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 DUF3812 PF12757.2 EPS27590.1 - 1.4e-34 118.8 15.8 1.4e-34 118.8 11.0 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF3812) YrhK PF14145.1 EPS27591.1 - 0.0003 20.3 16.0 0.34 10.5 1.1 4.6 4 1 0 4 4 4 3 YrhK-like protein PROL5-SMR PF15621.1 EPS27591.1 - 0.077 13.4 8.4 0.42 11.0 3.8 2.3 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family Mito_fiss_reg PF05308.6 EPS27591.1 - 0.3 10.4 5.0 0.28 10.5 1.7 1.8 2 0 0 2 2 2 0 Mitochondrial fission regulator MFS_1 PF07690.11 EPS27592.1 - 4.3e-29 101.3 22.8 4.3e-29 101.3 15.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS27592.1 - 3.5e-09 35.7 8.4 3.5e-09 35.7 5.8 3.6 3 1 0 3 3 3 2 Sugar (and other) transporter CFEM PF05730.6 EPS27593.1 - 6.2e-12 45.1 13.7 6.2e-12 45.1 9.5 2.2 3 1 0 3 3 3 1 CFEM domain Rifin_STEVOR PF02009.11 EPS27593.1 - 2.3 7.7 10.5 2.5 7.6 7.3 1.1 1 0 0 1 1 1 0 Rifin/stevor family Ilm1 PF10311.4 EPS27594.1 - 9.4e-42 142.3 12.3 4.3e-41 140.1 8.6 1.8 1 1 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 Trp_oprn_chp PF09534.5 EPS27594.1 - 0.011 15.2 0.6 0.025 14.2 0.1 1.7 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Prenyltrans PF00432.16 EPS27595.1 - 1.5e-36 123.6 13.8 5.9e-11 41.7 0.0 6.2 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EPS27595.1 - 9.5e-25 87.2 0.0 3.2e-18 66.1 0.0 3.2 2 1 1 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EPS27595.1 - 1.8e-05 24.7 0.0 0.011 15.7 0.0 3.8 3 1 0 3 3 3 1 Prenyltransferase-like Nucleoplasmin PF03066.10 EPS27595.1 - 0.0085 15.6 0.8 0.012 15.1 0.5 1.2 1 0 0 1 1 1 1 Nucleoplasmin DUF2457 PF10446.4 EPS27595.1 - 0.62 8.7 8.0 0.86 8.2 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 EPS27595.1 - 8.6 4.1 8.3 11 3.7 5.7 1.0 1 0 0 1 1 1 0 Nop14-like family APH PF01636.18 EPS27596.1 - 2.3e-11 43.9 0.0 1.3e-10 41.3 0.0 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 EPS27596.1 - 0.0014 17.8 0.1 0.0029 16.7 0.0 1.5 2 0 0 2 2 2 1 Ecdysteroid kinase DUF1679 PF07914.6 EPS27596.1 - 0.0024 16.5 0.0 1.1 7.8 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Fructosamin_kin PF03881.9 EPS27596.1 - 0.11 11.4 0.0 2.8 6.8 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase Pkinase PF00069.20 EPS27597.1 - 5.1e-67 225.7 0.0 8.4e-67 225.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS27597.1 - 1.2e-41 142.5 0.0 1.7e-41 141.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPS27597.1 - 3.3e-10 39.4 0.0 2e-08 33.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EPS27597.1 - 0.0066 15.5 0.4 0.029 13.4 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPS27597.1 - 0.28 10.8 8.6 2 8.1 0.1 3.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family MFS_1 PF07690.11 EPS27598.1 - 1.2e-16 60.3 27.3 1.2e-16 60.3 18.9 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS27598.1 - 0.00011 20.9 7.7 0.00011 20.9 5.3 2.9 1 1 1 3 3 3 1 Sugar (and other) transporter DUF2811 PF10929.3 EPS27598.1 - 0.021 14.8 0.1 0.05 13.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) DUF1049 PF06305.6 EPS27598.1 - 0.054 12.9 0.2 0.054 12.9 0.1 3.9 7 0 0 7 7 7 0 Protein of unknown function (DUF1049) HlyIII PF03006.15 EPS27598.1 - 0.15 11.4 11.8 0.019 14.3 1.4 2.8 1 1 1 3 3 2 0 Haemolysin-III related E1-E2_ATPase PF00122.15 EPS27599.1 - 5.3e-64 215.3 4.7 5.3e-64 215.3 3.3 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EPS27599.1 - 7.6e-47 159.1 9.5 9.5e-47 158.8 4.6 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EPS27599.1 - 4.3e-33 115.5 0.0 2.9e-31 109.5 0.0 2.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPS27599.1 - 4.5e-19 68.2 0.0 8.7e-19 67.2 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EPS27599.1 - 5.5e-18 65.8 0.0 1.9e-17 64.1 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EPS27599.1 - 1.3e-17 63.0 0.0 4.6e-17 61.2 0.0 2.1 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EPS27599.1 - 3.8e-08 33.2 1.3 6.5e-06 25.9 0.7 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EPS27599.1 - 0.014 15.6 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase 14-3-3 PF00244.15 EPS27601.1 - 2.5e-115 383.5 2.0 3.2e-115 383.1 1.4 1.1 1 0 0 1 1 1 1 14-3-3 protein DUF837 PF05769.6 EPS27601.1 - 0.012 15.1 0.5 14 5.1 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF837) DUF4085 PF13315.1 EPS27601.1 - 0.051 12.9 0.2 0.08 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) TPR_12 PF13424.1 EPS27601.1 - 0.056 13.3 0.2 8.2 6.4 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat HisKA PF00512.20 EPS27601.1 - 0.07 13.1 1.1 19 5.3 0.0 3.3 4 0 0 4 4 4 0 His Kinase A (phospho-acceptor) domain MCM_N PF14551.1 EPS27601.1 - 0.34 11.3 1.5 5.5 7.4 1.0 2.3 1 1 0 1 1 1 0 MCM N-terminal domain eIF3_subunit PF08597.5 EPS27602.1 - 1e-65 221.7 27.1 1.1e-65 221.5 18.8 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit ATC_hydrolase PF14196.1 EPS27602.1 - 0.14 12.5 0.1 0.14 12.5 0.0 2.3 2 0 0 2 2 2 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase Nha1_C PF08619.5 EPS27602.1 - 6.7 5.8 29.2 3.6 6.7 16.8 2.1 2 0 0 2 2 2 0 Alkali metal cation/H+ antiporter Nha1 C terminus Enolase_C PF00113.17 EPS27603.1 - 5.5e-152 504.8 0.1 7.5e-152 504.4 0.1 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EPS27603.1 - 1.1e-57 193.6 0.2 1.8e-57 192.9 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE PF01188.16 EPS27603.1 - 0.0055 17.2 0.0 0.014 15.8 0.0 1.8 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain AAA PF00004.24 EPS27604.1 - 4.9e-43 146.5 0.0 7.8e-43 145.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EPS27604.1 - 1.1e-06 28.7 0.0 4e-05 23.6 0.0 2.5 2 1 1 3 3 2 1 AAA ATPase domain AAA_2 PF07724.9 EPS27604.1 - 1.7e-06 28.0 0.0 5.5e-06 26.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EPS27604.1 - 2.4e-06 27.3 0.0 6.2e-05 22.7 0.0 2.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EPS27604.1 - 3.6e-06 26.2 0.0 6.4e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EPS27604.1 - 6.9e-06 26.2 0.0 0.0014 18.7 0.0 2.5 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 EPS27604.1 - 0.0003 19.8 0.0 0.0006 18.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 EPS27604.1 - 0.00091 18.9 0.0 0.002 17.8 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EPS27604.1 - 0.0015 19.3 0.4 0.0042 17.8 0.1 2.1 2 1 0 2 2 1 1 AAA domain Zeta_toxin PF06414.7 EPS27604.1 - 0.0016 17.5 0.0 0.0034 16.5 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin TIP49 PF06068.8 EPS27604.1 - 0.0025 16.6 0.0 0.0046 15.7 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_14 PF13173.1 EPS27604.1 - 0.0031 17.4 0.0 0.0077 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EPS27604.1 - 0.0032 16.9 0.0 0.0062 15.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activat PF00158.21 EPS27604.1 - 0.005 16.3 0.0 0.02 14.3 0.0 1.9 1 1 1 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 EPS27604.1 - 0.0052 15.9 0.0 0.0098 15.0 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EPS27604.1 - 0.0061 15.9 0.1 0.031 13.6 0.1 2.0 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 EPS27604.1 - 0.0071 16.2 0.0 0.022 14.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EPS27604.1 - 0.0072 16.6 0.0 0.019 15.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EPS27604.1 - 0.0072 15.9 0.0 0.017 14.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EPS27604.1 - 0.011 15.9 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase GAS PF13851.1 EPS27604.1 - 0.015 14.4 0.2 0.031 13.4 0.1 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding AAA_24 PF13479.1 EPS27604.1 - 0.022 14.3 0.1 0.045 13.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EPS27604.1 - 0.023 14.7 0.0 0.066 13.2 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.11 EPS27604.1 - 0.027 13.6 0.0 0.048 12.8 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.1 EPS27604.1 - 0.028 14.3 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EPS27604.1 - 0.031 13.3 0.0 0.11 11.5 0.0 2.0 1 1 1 2 2 2 0 KaiC UPF0079 PF02367.12 EPS27604.1 - 0.032 13.8 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Parvo_NS1 PF01057.12 EPS27604.1 - 0.048 12.5 0.0 0.075 11.8 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Arch_ATPase PF01637.13 EPS27604.1 - 0.057 13.1 0.0 0.24 11.0 0.0 2.0 1 1 0 1 1 1 0 Archaeal ATPase ResIII PF04851.10 EPS27604.1 - 0.062 13.1 0.0 0.19 11.5 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_11 PF13086.1 EPS27604.1 - 0.07 12.6 0.1 0.21 11.1 0.0 1.9 2 1 0 2 2 2 0 AAA domain NACHT PF05729.7 EPS27604.1 - 0.09 12.4 0.0 0.26 10.9 0.0 1.8 2 0 0 2 2 2 0 NACHT domain Glyco_hydro_47 PF01532.15 EPS27605.1 - 3e-165 550.2 0.0 3.5e-165 550.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Peptidase_M20 PF01546.23 EPS27606.1 - 6.2e-21 74.7 0.2 9.2e-21 74.2 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EPS27606.1 - 6e-19 67.8 0.1 1e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M42 PF05343.9 EPS27606.1 - 0.0042 15.8 0.0 0.42 9.3 0.0 2.9 3 0 0 3 3 3 1 M42 glutamyl aminopeptidase PNK3P PF08645.6 EPS27609.1 - 1.4e-57 193.5 0.0 2.3e-57 192.8 0.0 1.4 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 EPS27609.1 - 5.4e-28 97.6 0.0 2e-27 95.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain HAD_2 PF13419.1 EPS27609.1 - 4e-05 23.9 0.1 0.0098 16.1 0.0 3.2 1 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase KTI12 PF08433.5 EPS27609.1 - 4.8e-05 22.7 2.2 0.057 12.6 0.0 2.8 2 1 0 3 3 3 2 Chromatin associated protein KTI12 Spore_YhcN_YlaJ PF09580.5 EPS27609.1 - 0.0069 16.5 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) NIF PF03031.13 EPS27609.1 - 0.011 15.3 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase Zeta_toxin PF06414.7 EPS27609.1 - 0.013 14.5 0.0 0.28 10.2 0.0 2.5 3 0 0 3 3 3 0 Zeta toxin Hydrolase_6 PF13344.1 EPS27609.1 - 0.063 13.1 0.1 0.77 9.6 0.0 2.5 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Med18 PF09637.5 EPS27610.1 - 1.6e-65 221.1 0.0 1.8e-65 220.9 0.0 1.0 1 0 0 1 1 1 1 Med18 protein CSD PF00313.17 EPS27610.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain DUF2638 PF10937.3 EPS27611.1 - 4.7e-38 130.6 0.1 5.3e-38 130.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) RGS PF00615.14 EPS27612.1 - 6.2e-07 29.5 0.0 9.9e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Rhodanese PF00581.15 EPS27613.1 - 5.9e-10 39.4 0.0 1.5e-09 38.2 0.0 1.7 1 1 0 1 1 1 1 Rhodanese-like domain Sirohm_synth_M PF14824.1 EPS27613.1 - 0.15 11.0 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 Sirohaem biosynthesis protein central Isochorismatase PF00857.15 EPS27615.1 - 2.1e-19 70.1 0.2 1.3e-18 67.5 0.1 2.0 1 1 0 1 1 1 1 Isochorismatase family Fungal_trans_2 PF11951.3 EPS27616.1 - 4.3e-09 35.4 0.3 3.2e-05 22.6 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Pkinase PF00069.20 EPS27617.1 - 2.1e-36 125.4 0.0 2.6e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS27617.1 - 1.8e-14 53.4 0.0 2.2e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPS27617.1 - 0.017 14.8 0.0 0.56 9.9 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family DLIC PF05783.6 EPS27617.1 - 2.7 6.5 6.3 4 6.0 4.4 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Rtt106 PF08512.7 EPS27619.1 - 1.2e-26 92.5 0.0 2.7e-26 91.3 0.0 1.6 1 0 0 1 1 1 1 Histone chaperone Rttp106-like TFIIA PF03153.8 EPS27619.1 - 0.96 9.2 18.7 1.8 8.3 13.0 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cwf_Cwc_15 PF04889.7 EPS27619.1 - 1.4 8.5 17.5 2.4 7.8 12.1 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein KOW PF00467.24 EPS27620.1 - 0.0049 16.5 0.0 0.0094 15.6 0.0 1.5 1 0 0 1 1 1 1 KOW motif Fungal_trans PF04082.13 EPS27621.1 - 2.2e-12 46.3 0.2 3.5e-12 45.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF754 PF05449.6 EPS27621.1 - 0.15 12.0 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF754) bZIP_1 PF00170.16 EPS27622.1 - 1e-07 31.7 6.7 1.6e-07 31.1 4.7 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EPS27622.1 - 0.00013 21.7 11.0 0.00019 21.1 7.6 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EPS27622.1 - 0.004 17.4 2.4 0.004 17.4 1.6 2.0 3 0 0 3 3 3 1 bZIP Maf transcription factor RFXA_RFXANK_bdg PF15289.1 EPS27622.1 - 0.05 13.7 3.5 0.12 12.5 0.5 2.2 1 1 1 2 2 2 0 Regulatory factor X-associated C-terminal binding domain DUF1635 PF07795.6 EPS27622.1 - 0.28 10.5 2.1 0.52 9.6 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Homoserine_dh PF00742.14 EPS27623.1 - 5.2e-39 133.7 0.0 6.6e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 EPS27623.1 - 9.5e-13 48.5 0.0 2.4e-12 47.2 0.0 1.7 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Ras PF00071.17 EPS27625.1 - 1.5e-55 186.9 0.0 1.8e-55 186.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPS27625.1 - 9.6e-16 58.3 0.0 1.5e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPS27625.1 - 4.3e-07 29.3 0.0 6.9e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EPS27625.1 - 0.0015 17.8 0.0 0.002 17.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EPS27625.1 - 0.0017 17.8 0.0 0.0078 15.6 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EPS27625.1 - 0.041 13.0 0.0 0.048 12.8 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EPS27625.1 - 0.097 12.1 0.0 11 5.4 0.0 2.5 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF1712 PF08217.6 EPS27626.1 - 4.6e-15 54.9 0.0 6.2e-13 47.8 0.0 2.8 2 1 0 2 2 2 2 Fungal domain of unknown function (DUF1712) Formyl_trans_N PF00551.14 EPS27627.1 - 1.5e-21 76.7 0.1 2.6e-21 75.9 0.1 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 EPS27627.1 - 0.082 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 Formyl transferase, C-terminal domain Alg14 PF08660.6 EPS27628.1 - 3.7e-51 173.5 0.6 5.2e-51 173.0 0.0 1.5 2 0 0 2 2 2 1 Oligosaccharide biosynthesis protein Alg14 like Glyco_trans_4_4 PF13579.1 EPS27628.1 - 0.00085 19.5 0.7 0.0014 18.7 0.5 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain UPF0197 PF05251.7 EPS27628.1 - 0.17 12.2 1.5 0.36 11.1 1.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0197) Ima1_N PF09779.4 EPS27629.1 - 1.3e-38 132.4 3.2 2.3e-38 131.6 2.3 1.4 1 0 0 1 1 1 1 Ima1 N-terminal domain RNHCP PF12647.2 EPS27629.1 - 0.63 9.8 4.9 0.61 9.9 1.3 2.2 1 1 1 2 2 2 0 RNHCP domain OrfB_Zn_ribbon PF07282.6 EPS27629.1 - 0.98 9.1 2.7 1.3 8.6 0.5 2.1 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DZR PF12773.2 EPS27629.1 - 3.3 7.5 8.5 1.2 8.9 0.4 2.8 2 1 0 2 2 2 0 Double zinc ribbon Sugar_tr PF00083.19 EPS27630.1 - 8.2e-116 387.2 26.8 9.4e-116 387.0 18.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS27630.1 - 3.8e-18 65.3 49.9 1.7e-17 63.2 12.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily NmrA PF05368.8 EPS27631.1 - 1.2e-09 37.7 0.0 1.7e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPS27631.1 - 0.066 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding UBA_4 PF14555.1 EPS27631.1 - 0.11 12.0 1.5 5.8 6.5 0.0 3.5 4 0 0 4 4 4 0 UBA-like domain BPL_LplA_LipB PF03099.14 EPS27633.1 - 3.1e-15 56.2 0.0 6.5e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Chorismate_synt PF01264.16 EPS27634.1 - 1.3e-133 444.7 0.0 1.5e-133 444.5 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Kelch_4 PF13418.1 EPS27635.1 - 4.4e-06 26.3 3.4 0.28 10.9 0.0 4.6 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.1 EPS27635.1 - 0.0002 21.2 0.0 0.044 13.7 0.0 3.3 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.10 EPS27635.1 - 0.021 14.5 0.1 0.63 9.8 0.0 3.1 2 0 0 2 2 2 0 Kelch motif Kelch_3 PF13415.1 EPS27635.1 - 0.023 14.8 13.8 1.1 9.4 0.3 5.1 5 0 0 5 5 5 0 Galactose oxidase, central domain MLANA PF14991.1 EPS27635.1 - 0.077 13.0 0.0 0.36 10.8 0.0 2.1 1 1 1 2 2 2 0 Protein melan-A Pkinase PF00069.20 EPS27637.1 - 4.5e-54 183.3 0.5 4.4e-37 127.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPS27637.1 - 1.1e-27 96.7 0.0 1.2e-26 93.4 0.0 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPS27637.1 - 3.3e-05 23.0 0.0 8.6e-05 21.6 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EPS27637.1 - 0.00041 20.1 0.7 0.0032 17.2 0.5 2.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Glyco_hydro_53 PF07745.8 EPS27639.1 - 9.6e-109 363.1 0.1 1.1e-108 363.0 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Glyco_hydro_cc PF11790.3 EPS27639.1 - 0.027 13.9 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core zf-H2C2_2 PF13465.1 EPS27640.1 - 5.9e-14 51.5 7.4 5.5e-08 32.7 0.2 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EPS27640.1 - 4.3e-12 45.6 11.3 8.4e-06 25.8 1.6 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPS27640.1 - 5.1e-11 42.1 11.5 4.1e-05 23.6 1.8 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EPS27640.1 - 2.4e-07 30.6 1.8 0.031 14.4 0.1 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EPS27640.1 - 6.5e-05 22.9 2.4 0.014 15.5 0.2 3.4 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-Di19 PF05605.7 EPS27640.1 - 0.12 12.5 1.7 0.22 11.6 1.2 1.4 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 EPS27640.1 - 0.75 9.7 10.2 11 6.0 0.4 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger LIM PF00412.17 EPS27640.1 - 0.89 9.6 3.0 5.9 7.0 2.2 2.1 1 1 1 2 2 2 0 LIM domain Glycos_transf_1 PF00534.15 EPS27641.1 - 1e-17 64.1 0.0 1.8e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EPS27641.1 - 9.2e-11 42.0 0.0 1.1e-09 38.5 0.0 2.5 3 0 0 3 3 3 1 Glycosyl transferases group 1 AAA_5 PF07728.9 EPS27641.1 - 7.6e-05 22.4 0.1 0.00018 21.2 0.0 1.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Glyco_transf_4 PF13439.1 EPS27641.1 - 0.00012 21.8 0.0 0.00047 19.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.1 EPS27641.1 - 0.026 14.7 0.1 0.077 13.2 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EPS27641.1 - 0.2 11.7 0.0 0.2 11.7 0.0 2.8 2 1 0 2 2 2 0 Glycosyl transferase 4-like domain 60KD_IMP PF02096.15 EPS27642.1 - 6.1e-18 65.1 0.6 9.1e-18 64.6 0.4 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein PP2C PF00481.16 EPS27643.1 - 2.3e-40 138.6 0.0 4.8e-40 137.5 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EPS27643.1 - 2.3e-07 30.4 0.1 4.6e-06 26.1 0.0 2.2 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.7 EPS27643.1 - 3.8e-05 23.4 0.0 0.45 10.1 0.0 2.9 3 0 0 3 3 3 2 Stage II sporulation protein E (SpoIIE) Beta-lactamase2 PF13354.1 EPS27643.1 - 0.042 13.2 0.1 1.9 7.8 0.0 2.6 2 1 0 2 2 2 0 Beta-lactamase enzyme family Tcf25 PF04910.9 EPS27644.1 - 4.1e-87 292.4 0.1 6.6e-87 291.7 0.1 1.3 1 0 0 1 1 1 1 Transcriptional repressor TCF25 PGA2 PF07543.7 EPS27644.1 - 5.9 6.6 11.5 11 5.7 7.9 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 PQ-loop PF04193.9 EPS27645.1 - 2.4e-40 135.9 4.3 1.4e-20 72.5 0.0 2.7 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 EPS27645.1 - 0.11 12.3 1.3 0.42 10.4 0.0 2.3 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Ribosomal_60s PF00428.14 EPS27646.1 - 2.2e-27 95.2 11.0 2.7e-27 94.9 7.6 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2408 PF10303.4 EPS27647.1 - 1.2e-54 184.0 2.9 6.9e-34 116.8 0.9 5.0 3 2 2 5 5 5 4 Protein of unknown function (DUF2408) XhlA PF10779.4 EPS27647.1 - 0.017 14.9 1.8 3.3 7.7 0.1 3.4 3 0 0 3 3 3 0 Haemolysin XhlA MscS_porin PF12795.2 EPS27647.1 - 0.023 14.0 1.5 0.19 11.0 0.1 2.4 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain Spc7 PF08317.6 EPS27647.1 - 0.027 13.1 1.2 0.05 12.2 0.5 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein EzrA PF06160.7 EPS27647.1 - 0.03 12.5 1.6 0.52 8.4 0.0 2.2 1 1 0 2 2 2 0 Septation ring formation regulator, EzrA HR1 PF02185.11 EPS27647.1 - 0.039 13.7 1.3 0.89 9.3 0.1 3.1 2 1 1 3 3 3 0 Hr1 repeat DUF972 PF06156.8 EPS27647.1 - 0.06 13.6 0.2 0.28 11.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Prefoldin_2 PF01920.15 EPS27647.1 - 0.11 12.2 2.6 5.4 6.8 0.2 3.1 1 1 2 3 3 3 0 Prefoldin subunit DUF1664 PF07889.7 EPS27647.1 - 0.18 11.5 1.0 33 4.2 0.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) CorA PF01544.13 EPS27647.1 - 2.5 7.0 7.7 0.53 9.2 0.7 2.7 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein IncA PF04156.9 EPS27647.1 - 2.9 7.4 5.7 11 5.5 3.4 2.3 1 1 1 2 2 2 0 IncA protein Aconitase PF00330.15 EPS27648.1 - 8.9e-155 515.6 0.0 4e-154 513.5 0.0 1.8 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EPS27648.1 - 1.6e-39 134.9 0.0 2.5e-39 134.3 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain PALP PF00291.20 EPS27649.1 - 7.2e-53 179.8 0.0 9.1e-53 179.4 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ank_2 PF12796.2 EPS27650.1 - 6e-13 48.9 0.5 8.8e-09 35.5 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EPS27650.1 - 3.9e-09 35.8 0.1 0.0005 19.7 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EPS27650.1 - 1.6e-08 34.5 0.4 0.079 13.2 0.0 3.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPS27650.1 - 3.2e-08 33.0 0.1 0.009 16.1 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EPS27650.1 - 5e-05 23.6 0.1 0.063 13.8 0.0 3.3 3 2 1 4 4 4 2 Ankyrin repeats (many copies) PPR_3 PF13812.1 EPS27650.1 - 0.072 13.4 0.3 4.6 7.7 0.0 3.1 3 0 0 3 3 3 0 Pentatricopeptide repeat domain Polysacc_synt_2 PF02719.10 EPS27650.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TFIIS_C PF01096.13 EPS27651.1 - 2.9e-20 71.6 2.1 2.9e-20 71.6 1.5 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EPS27651.1 - 9.2e-07 28.4 4.9 2.4e-06 27.1 1.0 2.7 3 1 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 EPS27651.1 - 0.0015 18.2 4.1 0.11 12.2 0.2 2.5 2 1 0 2 2 2 2 Transposase zinc-ribbon domain Zn_ribbon_recom PF13408.1 EPS27651.1 - 0.0017 18.5 0.5 0.12 12.7 0.1 2.4 2 0 0 2 2 2 1 Recombinase zinc beta ribbon domain DUF2387 PF09526.5 EPS27651.1 - 0.0093 15.8 1.9 0.21 11.5 0.1 2.3 2 0 0 2 2 2 1 Probable metal-binding protein (DUF2387) NOB1_Zn_bind PF08772.6 EPS27651.1 - 0.045 13.5 1.5 0.15 11.8 0.1 2.1 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like IBR PF01485.16 EPS27651.1 - 0.086 12.7 8.2 2.8 7.8 0.3 2.9 2 1 0 2 2 2 0 IBR domain Elf1 PF05129.8 EPS27651.1 - 0.18 11.5 4.1 7.3 6.3 0.1 2.7 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like zinc_ribbon_4 PF13717.1 EPS27651.1 - 0.31 10.7 6.4 1.9 8.2 0.1 3.2 4 0 0 4 4 4 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 EPS27651.1 - 0.31 10.3 12.0 2.5 7.4 3.3 3.3 3 1 0 3 3 3 0 zinc-ribbon domain DZR PF12773.2 EPS27651.1 - 0.4 10.5 6.4 0.82 9.5 0.1 2.7 2 1 0 2 2 2 0 Double zinc ribbon DNA_RNApol_7kD PF03604.8 EPS27651.1 - 0.42 10.1 2.6 5 6.6 0.0 3.1 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Zn_Tnp_IS1 PF03811.8 EPS27651.1 - 1.1 8.8 8.5 0.11 11.9 0.8 2.8 3 1 0 3 3 3 0 InsA N-terminal domain zinc_ribbon_5 PF13719.1 EPS27651.1 - 1.1 8.8 7.8 1.7 8.2 0.1 3.1 4 0 0 4 4 4 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 EPS27651.1 - 3.1 7.1 9.6 3.7 6.9 0.8 3.1 3 1 0 3 3 3 0 TFIIB zinc-binding zf-H2C2_2 PF13465.1 EPS27651.1 - 3.4 8.1 7.5 17 5.8 0.1 3.7 4 0 0 4 4 4 0 Zinc-finger double domain Ogr_Delta PF04606.7 EPS27651.1 - 7.2 6.3 7.5 1.7 8.3 0.1 2.8 3 0 0 3 3 2 0 Ogr/Delta-like zinc finger zf-TFIIB PF13453.1 EPS27651.1 - 8 5.7 10.0 0.47 9.6 0.7 2.9 3 1 0 3 3 3 0 Transcription factor zinc-finger GTP_EFTU PF00009.22 EPS27652.1 - 7.1e-57 191.8 0.0 1.1e-56 191.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EPS27652.1 - 3.4e-36 123.3 0.1 1e-35 121.8 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EPS27652.1 - 3.4e-16 59.1 1.4 9.8e-16 57.6 1.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EPS27652.1 - 6.4e-05 22.5 0.3 0.00014 21.4 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EPS27652.1 - 0.0014 18.5 0.2 0.0045 16.9 0.2 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Semialdhyde_dhC PF02774.13 EPS27652.1 - 0.01 15.7 0.1 0.12 12.2 0.0 2.2 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, dimerisation domain MAGE PF01454.14 EPS27653.1 - 1.7e-42 145.0 0.0 2.2e-42 144.6 0.0 1.2 1 0 0 1 1 1 1 MAGE family Ribosomal_L27e PF01777.13 EPS27655.1 - 1e-36 124.9 1.4 1.3e-36 124.5 1.0 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EPS27655.1 - 0.00015 21.3 0.4 0.0004 19.9 0.2 1.7 1 0 0 1 1 1 1 KOW motif TRAM_LAG1_CLN8 PF03798.11 EPS27657.1 - 8e-52 175.6 16.9 1.4e-51 174.9 11.7 1.4 1 0 0 1 1 1 1 TLC domain SWIB PF02201.13 EPS27658.1 - 2.7e-16 58.9 0.0 1e-15 57.1 0.0 1.9 2 0 0 2 2 2 1 SWIB/MDM2 domain TRP_2 PF08344.6 EPS27658.1 - 0.14 12.1 0.7 23 4.9 0.0 2.6 2 0 0 2 2 2 0 Transient receptor ion channel II PCI PF01399.22 EPS27659.1 - 6.5e-21 74.6 1.4 2e-20 73.0 0.1 2.4 2 1 0 2 2 2 1 PCI domain DDRGK PF09756.4 EPS27659.1 - 7.5e-05 22.2 0.1 0.00013 21.4 0.1 1.3 1 0 0 1 1 1 1 DDRGK domain HTH_Crp_2 PF13545.1 EPS27659.1 - 0.0011 18.7 0.0 0.8 9.5 0.0 3.2 3 0 0 3 3 3 1 Crp-like helix-turn-helix domain TPR_8 PF13181.1 EPS27659.1 - 0.0015 18.1 4.1 9.3 6.2 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat PCI_Csn8 PF10075.4 EPS27659.1 - 0.019 14.7 0.4 0.052 13.3 0.2 1.7 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 Prefoldin_2 PF01920.15 EPS27659.1 - 0.031 14.0 0.7 0.031 14.0 0.5 2.4 3 0 0 3 3 2 0 Prefoldin subunit TPR_14 PF13428.1 EPS27659.1 - 0.042 14.4 11.0 11 6.9 0.0 6.3 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 EPS27659.1 - 0.095 12.6 16.0 1.4 8.9 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat CesA PF11439.3 EPS27659.1 - 0.11 12.4 0.5 20 5.2 0.0 3.8 3 2 0 3 3 3 0 Type III secretion system filament chaperone CesA TPR_1 PF00515.23 EPS27659.1 - 0.14 11.8 6.0 1.6 8.5 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 EPS27659.1 - 1.3 9.1 8.9 33 4.7 0.4 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat WD40 PF00400.27 EPS27660.1 - 7.3e-37 123.9 3.7 7e-08 32.0 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Sof1 PF04158.9 EPS27660.1 - 1.8e-28 98.3 9.9 3.7e-28 97.3 6.9 1.6 1 0 0 1 1 1 1 Sof1-like domain eIF2A PF08662.6 EPS27660.1 - 0.0055 16.4 0.2 0.015 15.0 0.0 1.8 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A adh_short PF00106.20 EPS27661.1 - 1e-28 100.3 0.1 1.6e-28 99.7 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPS27661.1 - 2.9e-15 56.6 0.0 4.3e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPS27661.1 - 4.5e-13 49.2 0.1 7.6e-13 48.5 0.1 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EPS27661.1 - 0.0003 20.0 0.0 0.00046 19.4 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) 3Beta_HSD PF01073.14 EPS27661.1 - 0.0045 15.7 0.2 0.0065 15.1 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Bacteriocin_IId PF09221.5 EPS27661.1 - 0.73 9.7 0.0 0.73 9.7 0.0 3.1 4 0 0 4 4 4 0 Bacteriocin class IId cyclical uberolysin-like PHD PF00628.24 EPS27662.1 - 1.6e-09 37.2 8.3 2.8e-09 36.5 5.8 1.4 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.17 EPS27662.1 - 0.011 15.4 2.4 0.011 15.4 1.7 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.1 EPS27662.1 - 0.026 13.8 5.0 0.082 12.1 3.5 1.9 1 1 0 1 1 1 0 PHD/FYVE-zinc-finger like domain Prok-RING_1 PF14446.1 EPS27662.1 - 0.46 10.2 8.7 0.04 13.6 2.7 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD_2 PF13831.1 EPS27662.1 - 0.5 9.7 14.2 0.095 12.0 6.2 2.4 2 1 0 2 2 2 0 PHD-finger zf-CHY PF05495.7 EPS27662.1 - 0.56 10.4 6.5 1.2 9.3 0.7 2.4 1 1 1 2 2 2 0 CHY zinc finger CoA_transf_3 PF02515.12 EPS27663.1 - 8.6e-61 204.5 0.0 1.2e-60 204.0 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Lum_binding PF00677.12 EPS27664.1 - 1.3e-37 127.5 0.2 2.8e-21 75.1 0.0 2.1 2 0 0 2 2 2 2 Lumazine binding domain DUF3127 PF11325.3 EPS27664.1 - 0.0088 16.0 0.1 0.049 13.6 0.1 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3127) MFS_1 PF07690.11 EPS27665.1 - 8e-32 110.3 46.2 2e-31 108.9 31.9 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EPS27665.1 - 1.3e-10 40.0 7.4 1.3e-10 40.0 5.1 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) AMP-binding PF00501.23 EPS27666.1 - 0 1078.1 0.0 5e-85 285.3 0.0 4.2 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.15 EPS27666.1 - 5.8e-129 429.2 0.4 4.7e-34 117.6 0.0 5.8 4 2 0 4 4 4 4 Condensation domain PP-binding PF00550.20 EPS27666.1 - 7.2e-46 154.3 6.7 2.7e-11 43.5 0.1 5.7 5 0 0 5 5 5 4 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EPS27666.1 - 2.9e-26 92.1 0.2 7.9e-05 23.5 0.0 4.8 4 0 0 4 4 4 4 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.11 EPS27666.1 - 4.3e-05 23.1 0.0 0.23 10.9 0.0 2.7 2 0 0 2 2 2 2 Wax ester synthase-like Acyl-CoA acyltransferase domain AATase PF07247.7 EPS27667.1 - 2.4e-24 85.7 0.0 5.8e-24 84.4 0.0 1.6 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 EPS27667.1 - 1.5e-07 30.5 0.0 0.0025 16.7 0.0 2.1 2 0 0 2 2 2 2 Condensation domain Peptidase_M20 PF01546.23 EPS27668.1 - 1.4e-21 76.8 0.4 1.9e-21 76.4 0.2 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.12 EPS27668.1 - 3.6e-07 30.0 0.0 1.8e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M28 M20_dimer PF07687.9 EPS27668.1 - 8.7e-05 22.2 0.0 0.00022 20.9 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_S9 PF00326.16 EPS27669.1 - 2e-39 135.0 1.5 2e-38 131.7 1.1 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EPS27669.1 - 1e-15 58.2 2.3 2.2e-15 57.1 1.6 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPS27669.1 - 4.6e-13 49.1 0.2 1.7e-12 47.2 0.1 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EPS27669.1 - 2.8e-09 36.7 0.0 0.00072 19.0 0.0 2.4 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 EPS27669.1 - 4.1e-08 33.0 0.0 7.3e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 EPS27669.1 - 6.4e-07 29.0 1.3 0.0031 16.9 0.9 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PD40 PF07676.7 EPS27669.1 - 8.3e-07 28.5 0.1 0.29 10.8 0.0 3.7 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat DLH PF01738.13 EPS27669.1 - 9.2e-06 25.0 0.0 0.0059 15.9 0.0 2.4 2 0 0 2 2 2 2 Dienelactone hydrolase family LIP PF03583.9 EPS27669.1 - 1.9e-05 24.0 0.6 0.0043 16.3 0.2 2.2 2 0 0 2 2 2 2 Secretory lipase FSH1 PF03959.8 EPS27669.1 - 0.00019 20.9 0.0 0.00042 19.8 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DPPIV_N PF00930.16 EPS27669.1 - 0.00042 19.0 0.4 0.69 8.4 0.0 2.9 2 1 1 3 3 3 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region BAAT_C PF08840.6 EPS27669.1 - 0.0014 18.3 0.0 0.0029 17.3 0.0 1.4 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal eIF2A PF08662.6 EPS27669.1 - 0.0026 17.4 0.0 1.8 8.2 0.0 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A AXE1 PF05448.7 EPS27669.1 - 0.0082 14.6 0.0 0.013 14.0 0.0 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Esterase PF00756.15 EPS27669.1 - 0.019 14.4 0.1 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Abhydrolase_4 PF08386.5 EPS27669.1 - 0.039 13.8 0.0 0.091 12.6 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein Ank PF00023.25 EPS27670.1 - 7e-20 69.7 2.0 1.7e-07 30.6 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 EPS27670.1 - 1e-19 70.6 1.4 1.1e-16 60.9 0.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EPS27670.1 - 1.2e-17 62.1 0.5 5e-06 26.2 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 EPS27670.1 - 5.2e-16 58.3 1.4 5.4e-13 48.7 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EPS27670.1 - 3.4e-13 49.7 1.1 6e-07 29.8 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Mto2_bdg PF12808.2 EPS27670.1 - 0.035 14.2 0.9 0.079 13.0 0.7 1.6 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region bZIP_2 PF07716.10 EPS27670.1 - 0.039 13.7 0.6 0.064 13.0 0.4 1.3 1 0 0 1 1 1 0 Basic region leucine zipper Brix PF04427.13 EPS27672.1 - 7.1e-59 198.6 0.3 9.4e-59 198.2 0.2 1.1 1 0 0 1 1 1 1 Brix domain RNA_pol_3_Rpc31 PF11705.3 EPS27672.1 - 0.011 15.6 24.8 0.023 14.6 17.2 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF4512 PF14975.1 EPS27672.1 - 1.1 10.1 4.3 0.73 10.6 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4512) DEAD PF00270.24 EPS27673.1 - 3.9e-46 156.6 0.0 6.5e-46 155.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPS27673.1 - 1.8e-25 88.5 0.0 4.1e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPS27673.1 - 1.4e-05 24.9 0.0 4.8e-05 23.2 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA PF00004.24 EPS27674.1 - 1.2e-40 138.7 0.0 2.4e-40 137.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EPS27674.1 - 3.4e-05 22.9 0.1 0.00011 21.2 0.0 1.9 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EPS27674.1 - 5.7e-05 22.8 0.0 0.00031 20.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EPS27674.1 - 0.00036 20.5 0.2 0.017 15.1 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.9 EPS27674.1 - 0.002 18.0 1.8 0.0096 15.8 0.0 2.9 3 1 0 3 3 3 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EPS27674.1 - 0.0026 16.7 0.0 0.0074 15.2 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF815) PhoH PF02562.11 EPS27674.1 - 0.0048 16.1 0.2 0.05 12.8 0.1 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_22 PF13401.1 EPS27674.1 - 0.0049 17.0 2.2 0.031 14.4 0.1 2.7 2 1 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 EPS27674.1 - 0.008 15.3 0.0 0.018 14.2 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EPS27674.1 - 0.0089 15.9 0.0 0.032 14.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EPS27674.1 - 0.012 15.3 0.3 0.031 14.0 0.2 1.6 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 EPS27674.1 - 0.024 14.0 0.1 0.051 12.9 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF496 PF04363.7 EPS27674.1 - 0.028 14.2 7.6 2.2 8.1 0.3 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF496) AAA_14 PF13173.1 EPS27674.1 - 0.036 13.9 0.0 0.25 11.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EPS27674.1 - 0.039 13.5 0.1 0.14 11.7 0.1 2.0 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EPS27674.1 - 0.039 13.3 1.0 0.47 9.8 0.1 2.5 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.1 EPS27674.1 - 0.043 14.6 0.1 0.043 14.6 0.0 3.0 2 2 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EPS27674.1 - 0.044 12.8 0.9 0.11 11.6 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_11 PF13086.1 EPS27674.1 - 0.43 10.1 3.7 0.83 9.1 0.0 2.5 2 1 1 3 3 3 0 AAA domain TauD PF02668.11 EPS27675.1 - 6.2e-42 144.0 0.2 1.4e-41 142.9 0.1 1.5 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 EPS27675.1 - 1.2e-05 25.6 0.0 2.4e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF971) 2OG-FeII_Oxy_3 PF13640.1 EPS27675.1 - 0.00022 21.6 1.1 0.014 15.8 0.1 2.5 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily CsiD PF08943.5 EPS27675.1 - 0.0061 15.4 0.0 0.019 13.9 0.0 1.7 1 1 0 1 1 1 1 CsiD MaoC_dehydratas PF01575.14 EPS27676.1 - 8.8e-24 83.2 0.0 1.6e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EPS27676.1 - 6.4e-10 38.9 0.0 1.5e-06 27.9 0.0 2.3 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase Methyltransf_31 PF13847.1 EPS27677.1 - 4.4e-13 49.0 0.0 5.8e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EPS27677.1 - 4.6e-11 42.3 0.0 7.5e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EPS27677.1 - 5.4e-11 42.5 0.0 1.4e-10 41.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS27677.1 - 9.8e-11 42.2 0.0 1.8e-10 41.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 EPS27677.1 - 8.8e-10 38.0 0.0 1.1e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_11 PF08241.7 EPS27677.1 - 3.1e-08 34.0 0.0 7e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPS27677.1 - 3.2e-06 26.9 0.0 5.3e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPS27677.1 - 8.6e-06 25.2 0.0 1.6e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EPS27677.1 - 9.8e-06 25.8 0.1 3.5e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.6 EPS27677.1 - 1.1e-05 24.3 0.1 1.6e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.15 EPS27677.1 - 1.9e-05 23.9 0.0 2.7e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 EPS27677.1 - 0.00017 21.6 0.0 0.00032 20.7 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_12 PF08242.7 EPS27677.1 - 0.0013 19.1 0.0 0.0026 18.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EPS27677.1 - 0.0014 18.0 0.0 0.0022 17.5 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.1 EPS27677.1 - 0.013 15.1 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 EPS27677.1 - 0.021 14.3 0.2 0.037 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.13 EPS27677.1 - 0.027 14.0 0.0 0.044 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Ubie_methyltran PF01209.13 EPS27677.1 - 0.028 13.5 0.1 0.064 12.3 0.0 1.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family TehB PF03848.9 EPS27677.1 - 0.029 13.5 0.0 0.057 12.5 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_24 PF13578.1 EPS27677.1 - 0.072 13.9 0.0 0.19 12.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 EPS27677.1 - 0.074 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_4 PF02390.12 EPS27677.1 - 0.11 11.4 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Per1 PF04080.8 EPS27679.1 - 2.3e-109 364.9 15.7 3.1e-109 364.5 10.9 1.1 1 0 0 1 1 1 1 Per1-like PGM_PMM_I PF02878.11 EPS27680.1 - 6.4e-17 61.3 0.1 2.2e-07 30.4 0.0 2.8 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EPS27680.1 - 9.7e-16 57.9 0.6 5.9e-15 55.4 0.1 2.4 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EPS27680.1 - 1.8e-11 43.8 0.3 6.6e-11 42.0 0.2 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 EPS27680.1 - 0.0012 18.8 0.1 0.0041 17.1 0.1 1.9 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III tRNA-synt_1c PF00749.16 EPS27681.1 - 8.3e-96 320.3 0.0 1.4e-95 319.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EPS27681.1 - 7.8e-31 107.0 0.0 3.8e-30 104.8 0.0 2.1 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), anti-codon binding domain THUMP PF02926.12 EPS27681.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 THUMP domain SNN_transmemb PF09049.5 EPS27681.1 - 0.33 10.6 0.6 0.62 9.8 0.4 1.3 1 0 0 1 1 1 0 Stannin transmembrane F-box-like PF12937.2 EPS27682.1 - 0.0019 17.9 0.4 0.0056 16.3 0.2 1.9 1 0 0 1 1 1 1 F-box-like Pkinase PF00069.20 EPS27684.1 - 2.9e-71 239.6 0.0 4.1e-71 239.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS27684.1 - 1.2e-30 106.5 0.0 1.8e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EPS27684.1 - 6.2e-13 49.0 0.3 6.2e-13 49.0 0.2 2.6 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 EPS27684.1 - 7.4e-09 34.9 0.0 1.2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EPS27684.1 - 0.0035 17.1 0.0 0.0063 16.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EPS27684.1 - 0.058 12.7 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 EPS27684.1 - 0.096 12.2 0.1 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 EPS27684.1 - 0.15 11.0 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CRC_subunit PF08624.5 EPS27685.1 - 1.9e-55 186.6 0.0 2.6e-55 186.1 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Snf7 PF03357.16 EPS27686.1 - 7.8e-35 119.7 21.7 7.8e-35 119.7 15.1 2.0 1 1 1 2 2 2 1 Snf7 DUF3138 PF11336.3 EPS27686.1 - 0.0078 14.4 5.0 0.0099 14.1 3.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3138) HlyD PF00529.15 EPS27686.1 - 0.019 14.2 10.0 0.032 13.5 6.9 1.3 1 0 0 1 1 1 0 HlyD family secretion protein Fmp27_WPPW PF10359.4 EPS27686.1 - 0.1 10.9 9.2 0.15 10.4 6.4 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain YlqD PF11068.3 EPS27686.1 - 0.42 10.6 20.2 1.4 8.9 6.3 2.3 1 1 1 2 2 2 0 YlqD protein Sas10 PF09368.5 EPS27686.1 - 0.51 10.5 3.4 0.86 9.8 1.6 1.8 1 1 1 2 2 2 0 Sas10 C-terminal domain TMCO5 PF14992.1 EPS27686.1 - 0.6 9.1 15.1 0.035 13.2 7.1 1.4 2 0 0 2 2 2 0 TMCO5 family Peptidase_S46 PF10459.4 EPS27686.1 - 0.64 8.3 12.1 0.7 8.2 8.4 1.2 1 0 0 1 1 1 0 Peptidase S46 IFT57 PF10498.4 EPS27686.1 - 1.1 7.8 14.7 0.51 9.0 8.3 1.7 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 NuA4 PF09340.5 EPS27686.1 - 1.5 8.5 6.3 0.49 10.0 0.3 2.9 3 0 0 3 3 3 0 Histone acetyltransferase subunit NuA4 Viral_P18 PF04521.8 EPS27686.1 - 4 6.9 9.3 1.2 8.5 2.6 2.6 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Ten1 PF12658.2 EPS27687.1 - 4.6e-41 139.4 0.0 5.4e-41 139.2 0.0 1.1 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.1 EPS27687.1 - 0.002 17.6 0.0 0.0034 16.9 0.0 1.5 1 1 0 1 1 1 1 Telomere-capping, CST complex subunit MoaE PF02391.12 EPS27687.1 - 0.039 13.7 0.0 0.14 12.0 0.0 1.7 2 0 0 2 2 2 0 MoaE protein MFS_1 PF07690.11 EPS27688.1 - 6.4e-42 143.5 31.9 8.5e-41 139.8 20.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS27688.1 - 1.3e-13 50.4 12.1 1.3e-13 50.4 8.4 1.9 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EPS27688.1 - 9.2e-08 30.7 4.7 9.2e-08 30.7 3.3 1.8 3 0 0 3 3 3 1 Fungal trichothecene efflux pump (TRI12) 3Beta_HSD PF01073.14 EPS27689.1 - 1e-25 90.0 0.0 3.6e-25 88.2 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EPS27689.1 - 1.5e-13 50.7 0.0 2.6e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EPS27689.1 - 1.7e-09 36.9 0.0 5.2e-09 35.4 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EPS27689.1 - 9.5e-07 28.9 0.0 2.9e-06 27.3 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EPS27689.1 - 2.2e-05 24.4 0.2 5.6e-05 23.1 0.2 1.6 1 1 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EPS27689.1 - 0.00013 21.0 0.0 0.0036 16.2 0.0 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EPS27689.1 - 0.00025 20.0 0.0 0.00043 19.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EPS27689.1 - 0.00065 19.4 0.4 0.003 17.2 0.3 2.0 1 1 0 1 1 1 1 KR domain BCAS2 PF05700.6 EPS27690.1 - 1.8e-58 197.6 1.0 1.9e-58 197.5 0.7 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Ceramidase_alk PF04734.8 EPS27691.1 - 1.8e-276 918.3 0.0 2.1e-276 918.1 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase Zn_clus PF00172.13 EPS27694.1 - 5.3e-08 32.6 10.7 5.3e-08 32.6 7.4 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EPS27694.1 - 0.0099 14.7 0.0 0.018 13.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain EI24 PF07264.6 EPS27695.1 - 4.9e-07 29.3 16.8 6.8e-07 28.9 11.7 1.2 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) HAD_2 PF13419.1 EPS27696.1 - 1e-29 103.9 0.0 1.3e-29 103.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EPS27696.1 - 2.4e-05 23.9 0.0 4.6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Cyt-b5 PF00173.23 EPS27697.1 - 3.3e-16 58.8 0.1 1.7e-15 56.5 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 EPS27697.1 - 1.7e-15 57.1 8.3 3.6e-15 56.1 5.7 1.5 1 0 0 1 1 1 1 Fatty acid desaturase ELO PF01151.13 EPS27698.1 - 5.1e-63 212.6 8.4 6e-63 212.4 5.8 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family HNH PF01844.18 EPS27699.1 - 0.0024 17.6 1.7 0.0051 16.6 1.2 1.6 1 0 0 1 1 1 1 HNH endonuclease GTP_EFTU PF00009.22 EPS27700.1 - 5.6e-36 123.7 2.0 3.5e-35 121.1 1.4 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EPS27700.1 - 1.3e-27 95.8 0.3 3.3e-27 94.5 0.2 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EPS27700.1 - 7.9e-12 45.1 0.8 9.2e-06 25.6 0.0 2.7 2 0 0 2 2 2 2 Elongation factor Tu domain 2 IF2_N PF04760.10 EPS27700.1 - 2.7e-11 42.9 0.0 6.6e-11 41.6 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.18 EPS27700.1 - 4.9e-07 29.7 0.1 1.1e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase zf-RanBP PF00641.13 EPS27700.1 - 8.8e-06 24.7 2.5 8.8e-06 24.7 1.7 2.7 2 1 0 2 2 2 1 Zn-finger in Ran binding protein and others SRPRB PF09439.5 EPS27700.1 - 0.00068 18.9 0.0 0.0018 17.5 0.0 1.7 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EPS27700.1 - 0.00093 19.6 0.1 0.0022 18.4 0.1 1.7 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPS27700.1 - 0.0012 18.0 0.0 0.0025 17.0 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.4 EPS27700.1 - 0.004 16.6 0.1 0.011 15.1 0.1 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 EPS27700.1 - 0.08 12.2 0.1 0.2 10.9 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B zf-C3HC4_3 PF13920.1 EPS27700.1 - 0.36 10.5 10.4 0.12 12.0 1.7 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.2 EPS27700.1 - 0.36 10.6 12.7 0.3 10.9 1.7 2.1 1 1 2 3 3 3 0 Double zinc ribbon Mito_carr PF00153.22 EPS27701.1 - 1.8e-65 216.6 4.3 1e-21 76.4 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Phage_base_V PF04717.7 EPS27701.1 - 0.1 12.5 0.1 0.37 10.7 0.0 1.9 2 0 0 2 2 2 0 Phage-related baseplate assembly protein Fungal_trans PF04082.13 EPS27702.1 - 3.5e-08 32.6 0.0 8e-08 31.4 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS27702.1 - 2.1e-05 24.3 2.8 4.9e-05 23.1 1.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EPS27703.1 - 2.4e-33 115.2 23.1 3.1e-33 114.9 16.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Bac_export_1 PF01311.15 EPS27703.1 - 4 6.6 13.3 1.1 8.4 0.3 2.8 3 0 0 3 3 3 0 Bacterial export proteins, family 1 Glyco_hydro_31 PF01055.21 EPS27704.1 - 3.3e-87 293.1 0.2 4.4e-87 292.7 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EPS27704.1 - 4.3e-14 52.1 0.0 1e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Galactose mutarotase-like Ribosomal_S2 PF00318.15 EPS27705.1 - 3.6e-51 173.3 0.0 4.6e-51 173.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S2 Rick_17kDa_Anti PF05433.10 EPS27706.1 - 1.8e-05 24.3 15.5 3.2e-05 23.4 10.8 1.4 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_Omp PF13488.1 EPS27706.1 - 0.0013 18.3 12.3 0.004 16.7 8.5 1.9 1 0 0 1 1 1 1 Glycine zipper TraT PF05818.7 EPS27706.1 - 0.15 11.4 2.1 0.24 10.7 1.4 1.3 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Transgly_assoc PF04226.8 EPS27706.1 - 2.1 8.5 11.6 3.2 7.8 8.0 1.3 1 0 0 1 1 1 0 Transglycosylase associated protein Git3 PF11710.3 EPS27709.1 - 1.7e-22 79.9 16.6 1.7e-22 79.9 11.5 1.7 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EPS27709.1 - 6.2e-09 35.5 0.0 6.2e-09 35.5 0.0 2.6 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term 2OG-FeII_Oxy_2 PF13532.1 EPS27710.1 - 1.6e-16 60.7 0.0 1.9e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EPS27710.1 - 4.8e-10 39.6 0.0 9.4e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CRAL_TRIO PF00650.15 EPS27711.1 - 7.7e-38 129.4 0.0 1.1e-37 128.9 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EPS27711.1 - 6.4e-10 39.0 0.1 2.2e-09 37.2 0.1 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EPS27711.1 - 4.4e-08 33.1 0.0 8.5e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF2625 PF10946.3 EPS27711.1 - 0.038 12.9 0.0 0.071 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF2625 p450 PF00067.17 EPS27712.1 - 2.3e-64 217.6 0.0 3.1e-64 217.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 EPS27713.1 - 1.4e-15 56.9 0.4 4e-15 55.4 0.3 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.3 EPS27715.1 - 5.3e-07 28.5 0.1 2.1e-06 26.6 0.0 1.7 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS27715.1 - 0.033 14.1 13.3 0.053 13.4 9.2 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain SURF6 PF04935.7 EPS27718.1 - 6.3e-50 169.4 38.6 6.3e-50 169.4 26.8 4.2 2 1 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.1 EPS27718.1 - 7.7e-24 83.5 1.7 7.7e-24 83.5 1.2 9.3 8 1 0 8 8 8 1 60S ribosome biogenesis protein Rrp14 Fer4 PF00037.22 EPS27720.1 - 5.4e-14 51.1 16.4 3.1e-08 32.8 2.8 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EPS27720.1 - 2.8e-12 46.8 10.8 4.2e-12 46.2 7.5 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EPS27720.1 - 1.9e-10 40.3 23.8 2.5e-08 33.5 9.2 1.8 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 EPS27720.1 - 5.5e-10 39.3 10.3 1e-09 38.5 7.1 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_21 PF14697.1 EPS27720.1 - 9.6e-10 38.1 5.2 5.7e-05 22.9 0.3 2.1 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 EPS27720.1 - 1.2e-09 38.7 8.4 6.1e-05 23.6 0.6 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_17 PF13534.1 EPS27720.1 - 6.3e-09 36.0 2.3 0.0007 19.9 0.3 2.3 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.1 EPS27720.1 - 6.5e-09 35.6 20.2 1.1e-05 25.3 8.3 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 EPS27720.1 - 1.1e-07 31.3 14.3 0.00057 19.6 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 EPS27720.1 - 4.1e-07 29.8 12.5 0.00056 20.0 2.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 EPS27720.1 - 6.1e-07 29.0 17.4 0.0012 18.6 3.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 EPS27720.1 - 7.6e-05 23.0 10.6 0.02 15.3 0.7 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_15 PF13459.1 EPS27720.1 - 0.0054 17.2 13.5 0.32 11.5 1.3 2.8 2 1 0 2 2 2 2 4Fe-4S single cluster domain Fer4_13 PF13370.1 EPS27720.1 - 0.0083 16.4 15.7 0.29 11.5 3.2 2.7 2 1 0 2 2 2 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 EPS27720.1 - 0.018 15.5 17.5 0.039 14.5 2.8 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 EPS27720.1 - 0.02 15.0 4.7 0.35 11.0 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_11 PF13247.1 EPS27720.1 - 0.11 12.4 4.4 0.18 11.7 3.1 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain PP-binding PF00550.20 EPS27721.1 - 1.6e-10 41.0 0.1 2.2e-10 40.6 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EPS27721.1 - 1.6e-06 28.0 0.1 2.3e-06 27.5 0.1 1.1 1 0 0 1 1 1 1 Acyl-carrier Ribosomal_L50 PF10501.4 EPS27721.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.6 1 1 0 1 1 1 0 Ribosomal subunit 39S GPP34 PF05719.6 EPS27722.1 - 5.3e-66 222.6 0.2 6.8e-66 222.2 0.1 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) DUF2183 PF09949.4 EPS27723.1 - 1.2e-31 108.5 0.1 3e-31 107.3 0.1 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) DUF3885 PF13021.1 EPS27723.1 - 0.1 12.2 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3885) ADH_zinc_N_2 PF13602.1 EPS27724.1 - 0.0016 19.3 0.1 0.0034 18.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF367 PF04034.8 EPS27725.1 - 5.5e-50 168.2 0.1 8.9e-50 167.5 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 EPS27725.1 - 1.2e-11 44.0 0.7 2.5e-11 42.9 0.5 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SDA1 PF05285.7 EPS27725.1 - 1.1 8.4 24.8 1.7 7.8 17.2 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 EPS27725.1 - 2.6 5.8 30.8 3.4 5.4 21.3 1.1 1 0 0 1 1 1 0 Nop14-like family VHS PF00790.14 EPS27726.1 - 9.6e-44 148.4 0.0 3.3e-43 146.6 0.0 1.9 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 EPS27726.1 - 2.1e-25 88.6 0.2 6.4e-25 87.0 0.1 1.8 1 0 0 1 1 1 1 GAT domain Alpha_adaptinC2 PF02883.15 EPS27726.1 - 2.2e-19 69.8 0.1 5.2e-19 68.6 0.1 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain DUF4139 PF13598.1 EPS27726.1 - 0.012 14.9 0.9 0.012 14.9 0.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4139) Mei5 PF10376.4 EPS27726.1 - 0.023 14.2 2.7 0.051 13.1 1.8 1.6 1 0 0 1 1 1 0 Double-strand recombination repair protein PRA-PH PF01503.12 EPS27726.1 - 0.34 11.2 0.0 0.34 11.2 0.0 3.0 2 1 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase DUF349 PF03993.7 EPS27726.1 - 1.1 9.4 5.3 0.42 10.7 0.1 2.7 3 0 0 3 3 3 0 Domain of Unknown Function (DUF349) CBS PF00571.23 EPS27728.1 - 1.9e-21 75.5 2.1 9e-07 28.5 0.0 5.1 5 0 0 5 5 5 4 CBS domain Peptidase_C14 PF00656.17 EPS27730.1 - 3.6e-74 249.5 0.0 4.3e-74 249.3 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 EPS27730.1 - 0.052 13.3 0.3 0.2 11.4 0.0 2.2 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain Cpn60_TCP1 PF00118.19 EPS27731.1 - 8.9e-142 473.1 2.9 1e-141 472.9 2.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Rep_fac_C PF08542.6 EPS27731.1 - 0.019 14.9 0.0 0.42 10.6 0.0 2.6 2 0 0 2 2 2 0 Replication factor C C-terminal domain HSDR_N_2 PF13588.1 EPS27731.1 - 0.12 12.1 0.3 0.36 10.6 0.1 1.9 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) zf-H2C2 PF09337.5 EPS27732.1 - 3.6e-22 77.4 5.1 6.3e-22 76.7 3.5 1.4 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Acetyltransf_1 PF00583.19 EPS27732.1 - 3.5e-06 26.9 0.0 6.7e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EPS27732.1 - 0.0017 18.3 0.0 0.0035 17.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EPS27732.1 - 0.011 15.8 0.0 0.024 14.7 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPS27732.1 - 0.05 13.3 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_8 PF13523.1 EPS27732.1 - 0.062 13.1 0.0 0.36 10.7 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain LANC_like PF05147.8 EPS27733.1 - 9.8e-29 100.0 0.0 1.5e-27 96.1 0.0 2.2 1 1 0 1 1 1 1 Lanthionine synthetase C-like protein BAG PF02179.11 EPS27734.1 - 4.3e-20 71.6 0.1 4.3e-20 71.6 0.1 1.7 2 0 0 2 2 2 1 BAG domain ubiquitin PF00240.18 EPS27734.1 - 0.0017 17.6 0.0 0.0038 16.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Zn_clus PF00172.13 EPS27735.1 - 0.0016 18.3 11.8 0.0031 17.3 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gly_transf_sug PF04488.10 EPS27736.1 - 1.4e-13 51.1 0.0 2.4e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EPS27736.1 - 0.0068 15.5 0.0 0.014 14.5 0.0 1.5 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein RTA1 PF04479.8 EPS27737.1 - 2.2e-47 161.4 6.2 2.2e-47 161.4 4.3 1.5 2 0 0 2 2 2 1 RTA1 like protein Abhydrolase_9_N PF15420.1 EPS27737.1 - 0.0085 15.8 2.8 0.0085 15.8 2.0 2.1 1 1 2 3 3 3 1 Alpha/beta-hydrolase family N-terminus DUF1279 PF06916.8 EPS27737.1 - 0.097 12.9 0.0 0.33 11.2 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) Glyco_hydro_11 PF00457.12 EPS27738.1 - 6.6e-43 146.1 18.8 1.1e-42 145.3 13.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 CBM_1 PF00734.13 EPS27738.1 - 1.6e-10 40.4 16.8 3.5e-10 39.3 10.2 2.8 2 0 0 2 2 2 1 Fungal cellulose binding domain Toxin_7 PF05980.7 EPS27738.1 - 2.1 8.4 10.6 5.1 7.2 7.3 1.7 1 0 0 1 1 1 0 Toxin 7 Uma2 PF05685.7 EPS27739.1 - 0.017 14.4 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Putative restriction endonuclease Glutaredoxin PF00462.19 EPS27741.1 - 3.7e-20 71.6 0.0 6.9e-20 70.7 0.0 1.5 2 0 0 2 2 2 1 Glutaredoxin DUF836 PF05768.9 EPS27741.1 - 0.0018 18.4 0.2 0.0037 17.4 0.2 1.7 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) TraF PF13728.1 EPS27741.1 - 0.0045 16.5 0.0 0.0055 16.2 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin PF00085.15 EPS27741.1 - 0.014 15.0 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_4 PF13462.1 EPS27741.1 - 0.028 14.4 0.7 1.5 8.8 0.1 2.1 1 1 1 2 2 2 0 Thioredoxin Thioredoxin_2 PF13098.1 EPS27741.1 - 0.033 14.3 0.1 0.05 13.8 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain DSBA PF01323.15 EPS27741.1 - 0.04 13.4 0.1 0.1 12.1 0.1 1.7 1 1 0 1 1 1 0 DSBA-like thioredoxin domain DUF4124 PF13511.1 EPS27741.1 - 0.066 13.2 0.0 0.088 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4124) Thioredoxin_9 PF14595.1 EPS27741.1 - 0.068 12.7 0.0 0.076 12.5 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Chalcone PF02431.10 EPS27742.1 - 9e-67 224.3 0.0 1.2e-66 223.9 0.0 1.1 1 0 0 1 1 1 1 Chalcone-flavanone isomerase KOW PF00467.24 EPS27743.1 - 1.4e-06 27.7 1.3 2.9e-06 26.7 0.9 1.5 1 0 0 1 1 1 1 KOW motif Bac_rhamnosid PF05592.6 EPS27744.1 - 1.1e-36 126.1 3.7 1.3e-24 86.3 3.8 2.7 1 1 1 2 2 2 2 Bacterial alpha-L-rhamnosidase Trehalase PF01204.13 EPS27744.1 - 0.0012 17.5 0.0 0.0019 16.9 0.0 1.2 1 0 0 1 1 1 1 Trehalase DUF608 PF04685.8 EPS27744.1 - 0.0085 14.8 3.2 0.015 14.0 2.2 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF608 Glyco_hydro_28 PF00295.12 EPS27745.1 - 5.6e-40 137.2 4.9 4.7e-39 134.2 3.4 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Fe-ADH PF00465.14 EPS27746.1 - 3.4e-63 213.4 0.0 1.1e-62 211.8 0.0 1.6 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EPS27746.1 - 1.2e-09 37.8 0.3 0.00017 20.9 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase HEAT_2 PF13646.1 EPS27747.1 - 2.3e-21 75.8 14.9 3.3e-05 24.0 0.0 8.9 7 2 1 8 8 8 5 HEAT repeats HEAT PF02985.17 EPS27747.1 - 2.2e-19 67.7 13.8 0.00087 19.1 0.0 12.2 13 0 0 13 13 12 3 HEAT repeat HEAT_EZ PF13513.1 EPS27747.1 - 3.7e-16 59.0 28.0 3.8e-08 33.5 0.2 11.0 9 2 3 12 12 11 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EPS27747.1 - 1.1e-09 38.5 0.1 0.0029 17.9 0.0 6.5 4 2 3 7 7 6 1 Vacuolar 14 Fab1-binding region RIX1 PF08167.7 EPS27747.1 - 2.9e-07 30.3 1.1 0.0028 17.3 0.0 5.4 4 2 3 7 7 7 1 rRNA processing/ribosome biogenesis Adaptin_N PF01602.15 EPS27747.1 - 5.2e-06 25.0 0.8 0.0022 16.3 0.1 3.8 3 1 0 3 3 3 1 Adaptin N terminal region Cnd1 PF12717.2 EPS27747.1 - 5.3e-06 26.3 0.5 1.2 8.9 0.0 5.0 3 2 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.3 EPS27747.1 - 8.8e-06 24.6 5.2 0.00014 20.7 0.1 4.3 5 1 1 6 6 6 1 RNAPII transcription regulator C-terminal CLASP_N PF12348.3 EPS27747.1 - 3.4e-05 23.3 0.5 0.26 10.6 0.0 5.2 5 2 1 6 6 6 1 CLASP N terminal Arm PF00514.18 EPS27747.1 - 0.00016 21.3 3.0 3.1 7.7 0.0 5.1 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat IBN_N PF03810.14 EPS27747.1 - 0.00074 19.3 0.3 0.029 14.2 0.0 3.5 3 0 0 3 3 3 1 Importin-beta N-terminal domain DUF4042 PF13251.1 EPS27747.1 - 0.0012 18.3 0.3 6.8 6.1 0.0 4.5 4 1 0 4 4 4 1 Domain of unknown function (DUF4042) Proteasom_PSMB PF10508.4 EPS27747.1 - 0.0023 16.2 0.3 0.11 10.7 0.0 2.7 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit DUF3385 PF11865.3 EPS27747.1 - 0.0067 16.3 0.1 36 4.2 0.0 4.6 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) CBS PF00571.23 EPS27748.1 - 2.2e-42 142.5 7.2 4.1e-10 39.2 0.0 5.1 5 0 0 5 5 5 4 CBS domain PB1 PF00564.19 EPS27748.1 - 2.1e-09 36.8 0.0 5.5e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 PB1 domain MSP1a PF11670.3 EPS27748.1 - 0.0069 16.2 7.7 0.072 12.9 0.3 2.3 2 0 0 2 2 2 2 Major surface protein 1a (MSP1a) Ribosomal_S26e PF01283.14 EPS27749.1 - 9.8e-52 174.0 7.2 1.1e-51 173.8 5.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.2 EPS27749.1 - 0.019 15.3 1.0 0.59 10.5 0.4 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain Zn_ribbon_2 PF12674.2 EPS27749.1 - 0.068 13.5 0.3 10 6.5 0.0 2.3 1 1 1 2 2 2 0 Putative zinc ribbon domain DUF1918 PF08940.6 EPS27749.1 - 0.14 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) F-box-like PF12937.2 EPS27750.1 - 4.3e-06 26.3 0.9 1.5e-05 24.6 0.6 2.0 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 EPS27750.1 - 0.00043 20.0 0.1 2.9 8.2 0.0 4.7 5 0 0 5 5 5 1 Leucine Rich repeat LRR_8 PF13855.1 EPS27750.1 - 0.0079 15.9 0.3 1.4 8.7 0.3 4.0 3 1 2 5 5 5 2 Leucine rich repeat F-box PF00646.28 EPS27750.1 - 0.028 14.0 0.2 0.028 14.0 0.1 2.7 3 0 0 3 3 3 0 F-box domain LRR_7 PF13504.1 EPS27750.1 - 0.28 11.5 1.5 1.6e+02 3.2 0.0 4.9 5 0 0 5 5 5 0 Leucine rich repeat LMBR1 PF04791.11 EPS27751.1 - 3.8e-30 104.8 4.4 5.1e-30 104.4 3.1 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein NAD_binding_9 PF13454.1 EPS27751.1 - 0.053 13.2 0.1 0.24 11.1 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding IncA PF04156.9 EPS27751.1 - 0.089 12.3 0.0 0.089 12.3 0.0 2.4 2 0 0 2 2 2 0 IncA protein DUF3165 PF11364.3 EPS27751.1 - 3 8.0 9.0 0.94 9.6 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3165) Med15_fungi PF05397.7 EPS27754.1 - 5.9e-16 58.4 0.1 5.9e-16 58.4 0.0 4.1 4 0 0 4 4 4 1 Mediator complex subunit 15 EamA PF00892.15 EPS27756.1 - 4e-10 39.8 17.3 1.4e-05 25.0 1.8 3.0 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.10 EPS27756.1 - 2.4e-09 36.6 0.2 3.9e-09 35.9 0.1 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 EPS27756.1 - 1.4e-08 34.0 3.6 2.5e-08 33.1 2.5 1.3 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EPS27756.1 - 1.5e-05 24.7 13.4 0.002 17.7 4.2 2.4 2 0 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 EPS27756.1 - 0.00044 20.4 4.5 0.00044 20.4 3.1 3.3 2 1 1 3 3 3 1 Multidrug resistance efflux transporter Adaptin_N PF01602.15 EPS27757.1 - 1.4e-139 465.8 0.8 1.7e-139 465.5 0.5 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EPS27757.1 - 3.7e-18 65.9 0.0 6.6e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 EPS27757.1 - 4.9e-08 33.1 1.6 0.19 12.0 0.0 4.4 2 1 1 4 4 4 3 HEAT repeats HEAT PF02985.17 EPS27757.1 - 0.00082 19.2 1.5 13 6.1 0.0 5.0 4 1 0 4 4 4 1 HEAT repeat Arm PF00514.18 EPS27757.1 - 0.0011 18.6 0.5 29 4.6 0.1 5.9 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat TIP120 PF08623.5 EPS27757.1 - 0.0027 17.3 0.5 0.025 14.1 0.0 2.5 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) HEAT_EZ PF13513.1 EPS27757.1 - 0.0054 17.1 0.2 6.4 7.4 0.0 5.1 3 1 2 5 5 5 1 HEAT-like repeat Cnd1 PF12717.2 EPS27757.1 - 0.0054 16.5 2.2 0.027 14.3 0.8 2.8 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 MBOAT PF03062.14 EPS27758.1 - 2.5e-39 135.3 11.1 3.8e-39 134.6 7.7 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF3671 PF12420.3 EPS27758.1 - 2.8 7.9 4.6 1.5 8.8 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function DnaJ PF00226.26 EPS27760.1 - 2.5e-22 78.3 0.4 2.5e-22 78.3 0.2 2.1 2 1 0 2 2 2 1 DnaJ domain IncA PF04156.9 EPS27760.1 - 1.8 8.0 5.1 6.2 6.3 3.5 1.8 1 0 0 1 1 1 0 IncA protein Ribosomal_L13 PF00572.13 EPS27763.1 - 7.9e-28 97.0 0.1 1.6e-27 96.0 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L13 DSBA PF01323.15 EPS27763.1 - 0.057 12.9 0.0 0.094 12.2 0.0 1.4 1 0 0 1 1 1 0 DSBA-like thioredoxin domain GFO_IDH_MocA PF01408.17 EPS27764.1 - 1.5e-21 77.0 0.2 2.7e-21 76.3 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EPS27764.1 - 0.071 12.9 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain AMP-binding PF00501.23 EPS27765.1 - 9e-72 241.7 0.0 1.1e-71 241.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPS27765.1 - 6e-16 59.1 0.0 1.3e-15 58.1 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain F-box-like PF12937.2 EPS27766.1 - 2.3e-13 49.6 0.8 1.1e-12 47.4 0.1 2.5 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 EPS27766.1 - 2.1e-12 46.6 11.6 0.012 15.3 0.0 6.8 3 1 4 7 7 7 7 Leucine rich repeat LRR_4 PF12799.2 EPS27766.1 - 3.3e-12 45.7 4.8 0.061 12.9 0.0 7.0 5 2 1 7 7 7 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EPS27766.1 - 3e-06 26.7 14.7 13 6.2 0.0 10.5 13 0 0 13 13 13 1 Leucine Rich repeat LRR_1 PF00560.28 EPS27766.1 - 0.00089 18.9 18.8 34 5.0 0.0 9.8 9 2 0 9 9 9 0 Leucine Rich Repeat F-box PF00646.28 EPS27766.1 - 0.001 18.6 0.2 0.0044 16.6 0.1 2.2 1 0 0 1 1 1 1 F-box domain DUF1699 PF08004.6 EPS27766.1 - 0.037 13.5 1.5 0.39 10.2 0.1 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF1699) Peptidase_M28 PF04389.12 EPS27767.1 - 9.3e-31 106.9 0.1 1.4e-30 106.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EPS27767.1 - 0.00025 20.6 0.0 0.00026 20.5 0.0 1.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 DUF3767 PF12597.3 EPS27767.1 - 0.1 12.2 0.9 0.2 11.2 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) Med10 PF09748.4 EPS27770.1 - 3.4e-43 146.5 0.0 4e-43 146.3 0.0 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex NPV_P10 PF05531.7 EPS27770.1 - 0.084 13.1 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF3877 PF12993.2 EPS27770.1 - 0.098 12.2 0.0 0.11 12.0 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) adh_short PF00106.20 EPS27771.1 - 3.3e-06 27.0 0.0 6e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPS27771.1 - 5.6e-05 22.8 0.0 0.00013 21.7 0.0 1.6 2 0 0 2 2 2 1 KR domain Pkinase PF00069.20 EPS27772.1 - 4.5e-39 134.1 0.0 6.6e-39 133.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS27772.1 - 1.9e-32 112.3 0.0 2.7e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPS27772.1 - 0.0035 16.3 0.0 0.0055 15.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EPS27772.1 - 0.025 13.6 0.0 0.046 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PB1 PF00564.19 EPS27772.1 - 0.15 11.7 0.1 0.38 10.4 0.1 1.6 1 0 0 1 1 1 0 PB1 domain TPR_11 PF13414.1 EPS27774.1 - 8.8e-31 105.3 24.6 1.3e-17 63.1 2.2 4.7 3 1 1 4 4 4 4 TPR repeat DnaJ PF00226.26 EPS27774.1 - 8.2e-30 102.3 3.7 8.2e-30 102.3 2.6 2.6 3 0 0 3 3 3 1 DnaJ domain TPR_1 PF00515.23 EPS27774.1 - 1.7e-23 81.1 13.9 2.6e-08 33.1 0.5 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 EPS27774.1 - 1.2e-22 77.9 13.9 7.3e-07 28.6 0.3 5.9 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.1 EPS27774.1 - 2.3e-19 69.5 11.7 1.1e-07 32.3 0.8 4.7 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EPS27774.1 - 5.9e-15 54.4 7.9 0.001 19.4 0.1 5.8 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 EPS27774.1 - 6.6e-13 48.8 19.8 2.4e-06 27.8 2.1 5.3 3 3 3 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 EPS27774.1 - 1.3e-12 46.5 4.9 0.011 15.5 0.0 6.2 6 1 0 6 6 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 EPS27774.1 - 8.5e-12 44.8 11.3 1.1e-05 25.2 1.4 4.4 3 1 1 4 4 4 4 Tetratricopeptide repeat Apc3 PF12895.2 EPS27774.1 - 6.3e-11 42.2 4.7 3.7e-05 23.7 0.4 3.9 2 1 1 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 EPS27774.1 - 1.8e-08 34.1 4.8 0.0065 16.3 0.1 3.9 3 1 1 4 4 4 3 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.1 EPS27774.1 - 2.4e-07 30.4 10.1 0.018 15.1 0.3 5.2 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EPS27774.1 - 2.9e-06 26.6 15.5 0.0003 20.3 0.2 6.3 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 EPS27774.1 - 4.3e-06 26.8 13.7 0.092 13.2 0.1 6.5 6 1 0 6 6 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 EPS27774.1 - 4.4e-05 22.6 3.4 0.11 11.5 0.1 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 EPS27774.1 - 0.00019 21.2 4.3 0.3 10.9 0.1 3.5 1 1 2 3 3 3 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 EPS27774.1 - 0.0021 18.3 4.2 0.88 9.7 0.7 3.6 2 1 1 3 3 3 2 Alkyl sulfatase dimerisation RPT PF13446.1 EPS27774.1 - 0.019 14.3 3.4 0.96 8.9 0.0 3.9 3 2 1 4 4 4 0 A repeated domain in UCH-protein DUF3808 PF10300.4 EPS27774.1 - 0.024 13.1 0.1 5.1 5.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3808) FAT PF02259.18 EPS27774.1 - 0.029 13.3 0.8 0.076 11.9 0.3 1.8 2 0 0 2 2 2 0 FAT domain MIT PF04212.13 EPS27774.1 - 0.059 13.2 7.4 3 7.7 0.4 4.4 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_20 PF14561.1 EPS27774.1 - 0.15 12.2 3.4 2.6 8.2 0.1 3.0 1 1 1 3 3 3 0 Tetratricopeptide repeat SPO22 PF08631.5 EPS27774.1 - 0.29 10.1 2.7 0.3 10.1 0.6 2.0 2 1 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like BTAD PF03704.12 EPS27774.1 - 0.4 10.9 6.9 1.9 8.7 0.1 3.3 3 1 0 3 3 3 0 Bacterial transcriptional activator domain HHH_8 PF14716.1 EPS27774.1 - 0.68 10.1 3.9 24 5.1 0.1 3.6 3 0 0 3 3 3 0 Helix-hairpin-helix domain TPR_3 PF07720.7 EPS27774.1 - 1.1 9.1 5.5 2.9 7.7 0.1 3.3 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 EPS27774.1 - 1.3 9.0 11.4 5.9 6.9 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Pkinase PF00069.20 EPS27778.1 - 2.9e-61 206.8 0.0 3.6e-61 206.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS27778.1 - 2.8e-36 124.9 0.0 3.8e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPS27778.1 - 6.2e-09 35.2 0.0 9e-09 34.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Sec39 PF08314.6 EPS27779.1 - 7.8e-228 757.9 7.6 8.9e-228 757.7 5.3 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Ndufs5 PF10200.4 EPS27780.1 - 0.00015 21.7 0.1 0.00018 21.4 0.1 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.3 EPS27780.1 - 0.002 18.2 0.4 0.0033 17.5 0.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3128) CHCH PF06747.8 EPS27780.1 - 0.0072 16.2 0.2 0.012 15.4 0.2 1.3 1 0 0 1 1 1 1 CHCH domain COX6B PF02297.12 EPS27780.1 - 0.029 14.3 0.3 0.045 13.7 0.2 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb DUF3535 PF12054.3 EPS27781.1 - 1.4e-147 491.8 0.0 4.6e-147 490.2 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 EPS27781.1 - 6e-72 241.9 0.0 1e-71 241.2 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPS27781.1 - 2.6e-14 52.8 0.0 6.8e-14 51.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.17 EPS27781.1 - 5.8e-11 41.5 22.0 0.07 13.2 0.0 10.4 11 0 0 11 11 11 3 HEAT repeat HEAT_2 PF13646.1 EPS27781.1 - 5.7e-06 26.5 16.3 0.0028 17.9 0.3 7.1 6 2 1 7 7 7 2 HEAT repeats Vac14_Fab1_bd PF12755.2 EPS27781.1 - 4.1e-05 23.8 0.0 1.3 9.4 0.0 4.0 3 1 1 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EPS27781.1 - 0.0033 17.8 20.2 0.29 11.6 0.1 8.6 10 0 0 10 10 10 1 HEAT-like repeat U3_snoRNA_assoc PF08297.6 EPS27781.1 - 0.0096 16.1 0.3 0.033 14.4 0.2 1.9 1 0 0 1 1 1 1 U3 snoRNA associated Cnd1 PF12717.2 EPS27781.1 - 0.052 13.3 0.6 20 5.0 0.0 4.6 5 1 1 6 6 6 0 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 EPS27781.1 - 0.12 11.6 0.3 31 3.8 0.1 3.5 2 2 1 3 3 3 0 CLASP N terminal Abhydrolase_2 PF02230.11 EPS27783.1 - 7.9e-31 107.1 0.0 5.1e-22 78.3 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EPS27783.1 - 7e-08 32.6 1.2 2.2e-07 31.0 0.8 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPS27783.1 - 6.6e-06 25.9 0.0 1.2e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EPS27783.1 - 0.00085 18.6 0.0 0.0038 16.4 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family LIP PF03583.9 EPS27783.1 - 0.022 13.9 0.0 0.046 12.9 0.0 1.6 2 0 0 2 2 2 0 Secretory lipase Esterase_phd PF10503.4 EPS27783.1 - 0.027 13.7 0.0 6.2 6.0 0.0 2.2 2 0 0 2 2 2 0 Esterase PHB depolymerase Pro_racemase PF05544.6 EPS27784.1 - 8.1e-123 409.3 0.1 9.2e-123 409.2 0.0 1.0 1 0 0 1 1 1 1 Proline racemase Aa_trans PF01490.13 EPS27785.1 - 1.9e-56 191.2 39.8 2.2e-56 191.1 27.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Erythro_esteras PF05139.9 EPS27786.1 - 8.6e-144 478.9 1.4 1e-143 478.7 1.0 1.0 1 0 0 1 1 1 1 Erythromycin esterase Scs3p PF10261.4 EPS27788.1 - 7.6e-63 211.7 2.2 9.8e-63 211.3 1.5 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM CDV3 PF15359.1 EPS27789.1 - 0.32 11.0 5.5 3.6 7.6 2.2 2.6 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 ABC_tran PF00005.22 EPS27791.1 - 3.6e-38 130.9 0.0 3.5e-22 79.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EPS27791.1 - 4e-12 46.1 9.5 4e-12 46.1 6.6 4.8 5 1 0 5 5 3 1 ABC transporter transmembrane region AAA_16 PF13191.1 EPS27791.1 - 4e-09 36.7 0.1 0.00011 22.2 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EPS27791.1 - 4.3e-09 35.7 0.4 0.00015 21.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EPS27791.1 - 2.8e-06 26.6 0.1 0.019 14.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA PF00004.24 EPS27791.1 - 3.2e-06 27.3 0.0 0.014 15.6 0.0 3.2 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.1 EPS27791.1 - 3.4e-06 27.2 0.1 0.13 12.2 0.0 3.5 2 1 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.18 EPS27791.1 - 4.5e-06 26.6 0.0 0.062 13.2 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Zeta_toxin PF06414.7 EPS27791.1 - 1.1e-05 24.6 0.2 0.022 13.8 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_25 PF13481.1 EPS27791.1 - 1.2e-05 24.7 0.4 0.035 13.5 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EPS27791.1 - 2.8e-05 23.8 0.2 0.23 11.1 0.1 3.5 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Miro PF08477.8 EPS27791.1 - 5.1e-05 23.7 0.1 0.048 14.1 0.0 2.9 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 EPS27791.1 - 6.2e-05 23.1 0.0 0.28 11.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EPS27791.1 - 0.00014 21.7 0.0 0.041 13.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EPS27791.1 - 0.00019 20.7 1.2 1.6 7.8 0.0 3.5 4 0 0 4 4 3 1 RecF/RecN/SMC N terminal domain T2SE PF00437.15 EPS27791.1 - 0.00029 19.8 0.1 0.29 10.0 0.0 2.2 2 0 0 2 2 2 2 Type II/IV secretion system protein RNA_helicase PF00910.17 EPS27791.1 - 0.00052 20.1 0.0 0.14 12.3 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.16 EPS27791.1 - 0.00086 18.5 0.2 0.61 9.2 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 EPS27791.1 - 0.0011 17.9 0.0 0.23 10.3 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_23 PF13476.1 EPS27791.1 - 0.0013 19.1 0.8 0.066 13.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EPS27791.1 - 0.0017 18.0 1.1 2.1 7.9 0.2 3.0 3 0 0 3 3 3 2 NACHT domain AAA_18 PF13238.1 EPS27791.1 - 0.0018 18.5 0.1 1.7 8.9 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EPS27791.1 - 0.0023 18.7 0.0 1.6 9.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EPS27791.1 - 0.0027 17.2 0.4 0.48 9.8 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain FtsK_SpoIIIE PF01580.13 EPS27791.1 - 0.0029 17.0 0.1 0.91 8.9 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family Dynamin_N PF00350.18 EPS27791.1 - 0.0032 17.3 1.5 1.6 8.5 0.2 2.4 2 0 0 2 2 2 2 Dynamin family Sigma54_activat PF00158.21 EPS27791.1 - 0.0038 16.7 0.0 0.061 12.7 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain cobW PF02492.14 EPS27791.1 - 0.0044 16.4 0.3 0.94 8.8 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 EPS27791.1 - 0.0082 15.0 0.1 0.3 9.9 0.0 2.4 2 1 0 2 2 2 1 NB-ARC domain AAA_24 PF13479.1 EPS27791.1 - 0.0082 15.7 1.0 0.18 11.3 0.3 2.2 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EPS27791.1 - 0.026 14.2 0.6 1.7 8.3 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.13 EPS27791.1 - 0.028 13.9 0.7 0.15 11.6 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Adeno_IVa2 PF02456.10 EPS27791.1 - 0.034 12.7 0.1 5 5.6 0.0 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_14 PF13173.1 EPS27791.1 - 0.036 13.9 0.1 1.4 8.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EPS27791.1 - 0.04 13.6 0.1 8.4 6.0 0.0 2.4 2 0 0 2 2 2 0 NTPase VirE PF05272.6 EPS27791.1 - 0.064 12.7 0.0 0.25 10.7 0.0 1.9 2 0 0 2 2 2 0 Virulence-associated protein E AAA_30 PF13604.1 EPS27791.1 - 0.094 12.2 0.1 7.2 6.1 0.1 2.5 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EPS27791.1 - 0.11 12.2 0.0 8.4 6.0 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase Rad17 PF03215.10 EPS27791.1 - 0.14 10.8 0.2 0.22 10.1 0.1 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein MCM PF00493.18 EPS27791.1 - 0.26 10.0 0.1 5.9 5.6 0.0 2.2 2 0 0 2 2 2 0 MCM2/3/5 family DAP3 PF10236.4 EPS27791.1 - 0.28 10.0 0.6 16 4.2 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 ATP-synt_ab PF00006.20 EPS27791.1 - 0.29 10.6 0.5 5.4 6.4 0.1 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain CBF_beta PF02312.12 EPS27791.1 - 0.31 10.6 0.0 0.57 9.7 0.0 1.3 1 0 0 1 1 1 0 Core binding factor beta subunit Guanylate_kin PF00625.16 EPS27791.1 - 0.32 10.4 0.2 1.3 8.4 0.0 2.0 2 0 0 2 2 2 0 Guanylate kinase Glyco_hydro_3 PF00933.16 EPS27792.1 - 1.9e-94 316.0 0.0 2.8e-94 315.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EPS27792.1 - 6e-53 179.6 0.0 9.4e-53 179.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EPS27792.1 - 6.4e-17 61.2 0.0 1.6e-16 60.0 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF11 PF01345.13 EPS27792.1 - 1.1 9.4 5.7 0.61 10.1 0.1 3.2 4 0 0 4 4 4 0 Domain of unknown function DUF11 SBF PF01758.11 EPS27794.1 - 5e-48 162.9 11.0 6.6e-48 162.5 6.2 2.2 2 0 0 2 2 2 1 Sodium Bile acid symporter family PufQ PF05398.6 EPS27794.1 - 9.6 6.3 6.6 1.3 9.1 1.1 2.2 2 1 1 3 3 3 0 PufQ cytochrome subunit bZIP_1 PF00170.16 EPS27795.1 - 0.0027 17.6 15.1 0.003 17.4 7.5 2.3 1 1 1 2 2 2 1 bZIP transcription factor EcoR124_C PF12008.3 EPS27795.1 - 0.039 13.1 0.9 0.057 12.6 0.6 1.2 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal FUSC PF04632.7 EPS27795.1 - 1.4 7.3 6.0 2.3 6.5 4.2 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family NP1-WLL PF11733.3 EPS27795.1 - 8.9 6.6 12.2 0.83 9.9 1.2 2.4 2 0 0 2 2 2 0 Non-capsid protein NP1 EBP PF05241.7 EPS27796.1 - 5.1e-05 22.3 7.3 0.00029 19.8 5.1 2.2 1 1 0 1 1 1 1 Emopamil binding protein Cytochrom_B_N PF00033.14 EPS27796.1 - 0.00077 18.8 0.1 0.00077 18.8 0.1 1.7 2 0 0 2 2 2 1 Cytochrome b(N-terminal)/b6/petB Fungal_trans PF04082.13 EPS27797.1 - 2.4e-25 88.9 0.0 4.2e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS27797.1 - 2.4e-09 36.9 11.9 3.9e-09 36.2 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Man-6-P_recep PF02157.10 EPS27798.1 - 4.3e-10 39.0 0.0 6e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.13 EPS27798.1 - 1e-08 35.0 0.1 0.00018 21.2 0.1 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.5 EPS27798.1 - 0.0001 21.6 0.0 0.00024 20.4 0.0 1.6 1 1 0 1 1 1 1 Autophagy-related protein 27 ERG4_ERG24 PF01222.12 EPS27799.1 - 2.7e-159 530.3 5.4 3e-159 530.1 3.7 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EPS27799.1 - 0.00012 21.4 0.2 0.00012 21.4 0.2 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1295) A_deamin PF02137.13 EPS27800.1 - 6.3e-47 160.5 0.0 1.6e-46 159.2 0.0 1.6 1 1 0 1 1 1 1 Adenosine-deaminase (editase) domain SF3b10 PF07189.6 EPS27801.1 - 3.4e-35 119.7 0.0 3.8e-35 119.5 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) L27_2 PF09045.5 EPS27801.1 - 0.096 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 L27_2 DUF3074 PF11274.3 EPS27802.1 - 1.4e-60 204.0 0.1 3.1e-60 202.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3074) HR1 PF02185.11 EPS27802.1 - 0.0066 16.1 15.5 0.055 13.2 0.2 2.6 2 0 0 2 2 2 2 Hr1 repeat AAA_23 PF13476.1 EPS27802.1 - 0.0088 16.3 7.9 1.1 9.5 5.8 2.3 2 0 0 2 2 2 1 AAA domain ATG16 PF08614.6 EPS27802.1 - 0.015 15.1 17.8 0.016 15.0 9.5 2.5 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) START PF01852.14 EPS27802.1 - 0.017 14.4 0.0 0.71 9.1 0.0 2.4 2 0 0 2 2 2 0 START domain IncA PF04156.9 EPS27802.1 - 0.5 9.9 18.7 0.38 10.3 10.4 2.3 2 0 0 2 2 2 0 IncA protein DUF3573 PF12097.3 EPS27802.1 - 0.74 8.3 2.5 1.3 7.5 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Pox_A_type_inc PF04508.7 EPS27802.1 - 1.4 8.8 9.1 0.13 12.0 1.1 3.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Seryl_tRNA_N PF02403.17 EPS27802.1 - 1.7 8.7 19.6 1.4 8.9 8.2 2.9 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TSC22 PF01166.13 EPS27802.1 - 3 7.8 8.9 0.71 9.8 1.1 3.4 3 1 1 4 4 4 0 TSC-22/dip/bun family DUF342 PF03961.8 EPS27802.1 - 3.5 5.9 14.9 0.69 8.2 7.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Atg14 PF10186.4 EPS27802.1 - 3.9 6.3 18.0 0.18 10.7 8.3 1.7 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 FlaC_arch PF05377.6 EPS27802.1 - 5.4 6.9 6.4 7.5 6.5 0.8 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Allexi_40kDa PF05549.6 EPS27802.1 - 5.9 6.1 11.4 9.7 5.3 3.0 2.6 3 0 0 3 3 3 0 Allexivirus 40kDa protein Bap31 PF05529.7 EPS27802.1 - 8.2 5.8 13.6 1.3 8.4 6.7 1.6 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like Mnd1 PF03962.10 EPS27802.1 - 8.6 5.9 16.1 1.9 8.1 8.0 2.1 2 0 0 2 2 2 0 Mnd1 family GST_N_3 PF13417.1 EPS27805.1 - 2.2e-10 40.6 0.0 1.1e-09 38.3 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EPS27805.1 - 2.2e-08 33.9 0.1 7.1e-08 32.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EPS27805.1 - 5.5e-07 29.3 1.9 9.3e-07 28.6 1.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EPS27805.1 - 0.0046 17.4 0.0 0.008 16.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_4 PF14834.1 EPS27805.1 - 0.025 14.5 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EPS27805.1 - 0.096 12.8 0.0 0.31 11.2 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Spc7 PF08317.6 EPS27807.1 - 0.0082 14.8 1.2 0.0095 14.6 0.8 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Caudo_TAP PF02413.12 EPS27807.1 - 0.013 15.7 0.7 0.014 15.5 0.5 1.2 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein LRRC37AB_C PF14914.1 EPS27807.1 - 0.043 13.2 0.0 0.054 12.9 0.0 1.2 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain IncA PF04156.9 EPS27807.1 - 3 7.3 7.3 3.8 7.0 5.1 1.1 1 0 0 1 1 1 0 IncA protein NT-C2 PF10358.4 EPS27808.1 - 2.7e-33 114.4 0.1 3.5e-33 114.0 0.1 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Myotub-related PF06602.9 EPS27809.1 - 4.9e-126 420.2 0.0 6.2e-126 419.9 0.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 EPS27809.1 - 0.05 13.8 0.1 0.16 12.2 0.0 1.8 2 0 0 2 2 2 0 Tyrosine phosphatase family Y_phosphatase PF00102.22 EPS27809.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Ribosomal_S3_C PF00189.15 EPS27810.1 - 7.9e-17 61.2 0.1 1.6e-16 60.3 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EPS27810.1 - 2.7e-12 46.0 0.1 4.7e-12 45.2 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 EPS27810.1 - 0.056 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 B3_4 PF03483.12 EPS27811.1 - 1.9e-25 89.2 0.0 3.7e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 EPS27811.1 - 7.2e-19 67.3 0.0 1.9e-15 56.4 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain HEAT PF02985.17 EPS27812.1 - 4.3e-41 135.3 19.6 0.0028 17.5 0.1 13.5 14 0 0 14 14 14 11 HEAT repeat HEAT_2 PF13646.1 EPS27812.1 - 2e-33 114.5 3.6 1.7e-08 34.6 0.0 7.2 2 2 6 8 8 8 8 HEAT repeats HEAT_EZ PF13513.1 EPS27812.1 - 7.9e-14 51.6 6.8 0.057 13.9 0.0 9.3 6 2 3 9 9 9 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EPS27812.1 - 1.8e-11 44.2 5.3 0.00086 19.6 0.1 7.4 5 2 5 10 10 10 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EPS27812.1 - 5e-08 31.7 10.2 2.2e-06 26.2 1.7 4.1 3 1 1 4 4 4 3 Adaptin N terminal region CLASP_N PF12348.3 EPS27812.1 - 0.002 17.4 2.1 0.4 10.0 0.1 4.2 3 2 1 4 4 4 1 CLASP N terminal DUF2435 PF10363.4 EPS27812.1 - 0.0095 15.8 4.3 4.8 7.1 0.1 4.4 3 1 1 4 4 4 1 Protein of unknown function (DUF2435) Arm PF00514.18 EPS27812.1 - 0.023 14.5 6.7 1.4 8.8 0.0 5.8 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat RIX1 PF08167.7 EPS27812.1 - 0.07 12.8 0.1 3.8 7.1 0.0 3.3 4 1 0 4 4 4 0 rRNA processing/ribosome biogenesis Cnd1 PF12717.2 EPS27812.1 - 0.072 12.9 4.9 4 7.2 0.0 4.6 3 1 2 6 6 6 0 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.4 EPS27812.1 - 0.44 8.7 5.4 0.88 7.7 0.1 3.0 2 1 0 3 3 3 0 Proteasome non-ATPase 26S subunit Ferric_reduct PF01794.14 EPS27813.1 - 2e-08 34.3 6.6 6.2e-08 32.7 2.4 2.4 2 1 0 2 2 2 1 Ferric reductase like transmembrane component Glyco_transf_90 PF05686.7 EPS27814.1 - 3.1e-18 65.6 9.0 1.1e-14 54.0 5.4 2.9 2 1 0 2 2 2 2 Glycosyl transferase family 90 Abhydrolase_6 PF12697.2 EPS27815.1 - 3.1e-25 89.3 7.0 1.4e-24 87.2 4.9 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPS27815.1 - 1.2e-09 38.1 4.7 1.4e-08 34.6 3.3 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPS27815.1 - 2.5e-09 37.0 1.2 2.1e-08 33.9 0.8 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.7 EPS27815.1 - 0.0026 17.1 0.0 0.045 13.0 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) EHN PF06441.7 EPS27815.1 - 0.014 15.3 0.3 0.029 14.3 0.0 1.7 2 0 0 2 2 2 0 Epoxide hydrolase N terminus Ser_hydrolase PF06821.8 EPS27815.1 - 0.02 14.5 0.1 0.16 11.6 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase Chlorophyllase2 PF12740.2 EPS27815.1 - 0.028 13.3 0.0 0.046 12.6 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme PGAP1 PF07819.8 EPS27815.1 - 0.075 12.5 0.0 0.18 11.3 0.0 1.6 1 1 0 1 1 1 0 PGAP1-like protein Glyco_transf_8 PF01501.15 EPS27816.1 - 2.3e-33 115.6 0.0 3.6e-33 114.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Nucleotid_trans PF03407.11 EPS27816.1 - 0.0046 16.7 0.0 0.0076 16.0 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Mannosyl_trans3 PF11051.3 EPS27816.1 - 0.17 11.1 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative DUF2788 PF10981.3 EPS27817.1 - 0.15 11.8 0.2 0.44 10.3 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2788) APH PF01636.18 EPS27818.1 - 1.7e-09 37.7 0.1 4.4e-09 36.4 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPS27818.1 - 0.0017 17.9 0.0 0.0023 17.5 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase Aa_trans PF01490.13 EPS27819.1 - 3.3e-41 141.1 29.4 4e-41 140.8 20.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CAAD PF14159.1 EPS27819.1 - 1.2 8.8 8.2 8.1 6.1 0.1 3.5 4 0 0 4 4 4 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase TGS PF02824.16 EPS27820.1 - 3.1e-21 74.9 0.1 7.6e-21 73.7 0.1 1.7 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EPS27820.1 - 2.3e-18 66.2 0.1 6.8e-18 64.7 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EPS27820.1 - 3.6e-10 39.3 0.1 2.7e-09 36.5 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EPS27820.1 - 1.8e-05 24.2 0.4 0.23 10.8 0.0 4.0 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EPS27820.1 - 0.00023 21.0 0.3 0.048 13.4 0.0 2.4 1 1 1 2 2 2 2 Dynamin family ArgK PF03308.11 EPS27820.1 - 0.0037 16.0 0.2 0.012 14.4 0.1 1.8 2 0 0 2 2 2 1 ArgK protein Arf PF00025.16 EPS27820.1 - 0.023 13.9 0.4 2 7.6 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Miro PF08477.8 EPS27820.1 - 0.023 15.1 0.1 0.07 13.6 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein HTH_Tnp_Tc5 PF03221.11 EPS27821.1 - 1.5e-15 56.7 0.0 3.3e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 EPS27821.1 - 1.3e-05 24.4 0.1 2.9e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_38 PF13936.1 EPS27821.1 - 0.0061 16.0 0.1 0.013 15.0 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 EPS27821.1 - 0.014 15.0 0.1 0.068 12.8 0.0 2.1 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_4 PF13613.1 EPS27821.1 - 0.023 14.2 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease MarR PF01047.17 EPS27821.1 - 0.024 14.3 0.0 0.086 12.5 0.0 2.0 1 0 0 1 1 1 0 MarR family HTH_10 PF04967.7 EPS27821.1 - 0.038 13.5 0.0 0.082 12.5 0.0 1.5 1 0 0 1 1 1 0 HTH DNA binding domain HTH_Crp_2 PF13545.1 EPS27821.1 - 0.14 11.9 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain PXA PF02194.10 EPS27823.1 - 9.4e-39 132.8 0.0 1.3e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 PXA domain Tecti-min-caps PF09300.5 EPS27823.1 - 0.057 13.2 0.7 10 5.9 0.0 2.4 2 0 0 2 2 2 0 Tectiviridae, minor capsid IU_nuc_hydro PF01156.14 EPS27824.1 - 6e-80 268.7 0.0 6.9e-80 268.5 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Vac_ImportDeg PF09783.4 EPS27825.1 - 3.4e-44 150.4 0.0 7.1e-44 149.4 0.0 1.5 2 0 0 2 2 2 1 Vacuolar import and degradation protein MFS_1 PF07690.11 EPS27826.1 - 1.6e-24 86.3 92.0 6.5e-21 74.4 40.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Trp_syntA PF00290.15 EPS27827.1 - 1.8e-93 311.8 0.0 1.5e-92 308.8 0.0 2.0 2 0 0 2 2 2 1 Tryptophan synthase alpha chain PALP PF00291.20 EPS27827.1 - 4.5e-41 141.0 0.2 7.4e-41 140.3 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Fungal_trans PF04082.13 EPS27828.1 - 4.5e-22 78.1 0.0 1e-21 76.9 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS27828.1 - 5.5e-06 26.1 10.4 1e-05 25.3 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S49_N PF08496.5 EPS27828.1 - 0.032 14.0 2.3 0.074 12.8 1.6 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal FAM176 PF14851.1 EPS27828.1 - 0.25 11.0 6.7 2 8.1 3.1 2.3 2 0 0 2 2 2 0 FAM176 family BAF1_ABF1 PF04684.8 EPS27828.1 - 0.52 9.0 17.9 0.79 8.5 12.4 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Med15 PF09606.5 EPS27828.1 - 0.77 7.8 24.3 1.1 7.3 16.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF912 PF06024.7 EPS27828.1 - 1.6 8.8 6.0 16 5.6 2.6 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4175 PF13779.1 EPS27828.1 - 6.6 4.3 23.7 11 3.5 16.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Baculo_PP31 PF05311.6 EPS27828.1 - 7.4 5.7 10.3 13 4.9 7.1 1.3 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) FimP PF09766.4 EPS27828.1 - 8.4 5.3 17.0 16 4.4 11.8 1.4 1 0 0 1 1 1 0 Fms-interacting protein Zn_clus PF00172.13 EPS27829.1 - 1.4e-11 44.0 9.8 2.3e-11 43.3 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EPS27829.1 - 1.7e-06 27.1 0.2 2.4e-06 26.6 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Papo_T_antigen PF02380.10 EPS27829.1 - 5.1 7.1 6.1 14 5.7 0.0 3.1 3 0 0 3 3 3 0 T-antigen specific domain NMO PF03060.10 EPS27830.1 - 1.4e-43 149.2 5.2 9.2e-43 146.6 3.6 2.0 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EPS27830.1 - 3.2e-08 32.8 1.5 0.0012 17.8 2.3 2.1 1 1 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EPS27830.1 - 2.5e-06 26.5 3.9 4.5e-06 25.7 2.7 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EPS27830.1 - 0.00021 20.3 0.1 0.00034 19.6 0.1 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase Ribosomal_L7Ae PF01248.21 EPS27831.1 - 3.8e-27 93.6 0.6 4.7e-27 93.3 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PucR PF07905.6 EPS27831.1 - 0.04 13.4 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family Ank_2 PF12796.2 EPS27832.1 - 1.2e-22 79.9 0.0 6.8e-17 61.5 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EPS27832.1 - 6.3e-20 70.7 0.3 3.7e-08 33.3 0.0 5.2 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 EPS27832.1 - 2.1e-18 65.0 0.1 1.2e-06 28.0 0.0 4.8 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 EPS27832.1 - 1.2e-15 57.5 0.0 5.2e-07 30.0 0.0 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPS27832.1 - 1.1e-12 46.8 0.0 0.00075 19.5 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Steroid_dh PF02544.11 EPS27834.1 - 1.3e-12 47.7 0.9 1.3e-12 47.7 0.6 1.7 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase 2OG-FeII_Oxy_2 PF13532.1 EPS27835.1 - 4.2e-16 59.3 0.0 2.5e-14 53.5 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EPS27835.1 - 0.0011 19.2 0.0 0.0023 18.1 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Rotamase_3 PF13616.1 EPS27836.1 - 8.4e-19 67.9 0.1 1.6e-18 67.0 0.0 1.5 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.16 EPS27836.1 - 3.6e-18 66.0 0.0 5.4e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 EPS27836.1 - 4.8e-06 27.1 0.1 8.1e-06 26.4 0.0 1.4 1 1 1 2 2 2 1 PPIC-type PPIASE domain UAA PF08449.6 EPS27837.1 - 2.5e-73 246.6 10.6 6.1e-73 245.3 7.4 1.5 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EPS27837.1 - 4.5e-08 33.1 28.6 1e-06 28.8 3.9 3.4 3 1 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 EPS27837.1 - 2.5e-07 30.0 3.6 0.0049 16.0 1.1 2.2 2 0 0 2 2 2 2 Nucleotide-sugar transporter EmrE PF13536.1 EPS27837.1 - 4.1e-06 26.9 16.3 0.00086 19.4 1.5 3.1 3 0 0 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 EPS27837.1 - 0.0039 16.8 7.5 0.0039 16.8 5.2 2.8 2 2 0 2 2 2 1 Triose-phosphate Transporter family Sen15 PF09631.5 EPS27838.1 - 3.9e-16 59.1 0.0 4.1e-15 55.8 0.0 2.1 1 1 0 1 1 1 1 Sen15 protein PH PF00169.24 EPS27839.1 - 1.7e-09 37.7 0.0 5e-09 36.3 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EPS27839.1 - 0.75 10.0 7.0 2.7 8.2 0.6 3.5 3 1 0 3 3 3 0 Pleckstrin homology domain Kri1_C PF12936.2 EPS27840.1 - 6e-32 109.4 0.6 6e-32 109.4 0.4 3.8 3 2 1 4 4 4 1 KRI1-like family C-terminal Kri1 PF05178.7 EPS27840.1 - 4.9e-29 100.5 23.0 4.9e-29 100.5 15.9 5.3 4 2 0 4 4 4 1 KRI1-like family LicD PF04991.8 EPS27840.1 - 0.0041 17.2 2.2 0.0041 17.2 1.5 2.6 2 1 0 2 2 2 1 LicD family DUF4381 PF14316.1 EPS27840.1 - 2.8 8.0 6.6 0.95 9.5 2.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Mito_carr PF00153.22 EPS27841.1 - 1.4e-68 226.6 5.7 2.9e-24 84.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Adeno_E3B PF03376.9 EPS27843.1 - 0.031 14.1 4.5 0.051 13.4 3.1 1.3 1 0 0 1 1 1 0 Adenovirus E3B protein Stb3 PF10330.4 EPS27844.1 - 2.9e-37 126.2 0.0 5.3e-37 125.4 0.0 1.4 1 0 0 1 1 1 1 Putative Sin3 binding protein COesterase PF00135.23 EPS27845.1 - 6.2e-85 285.9 0.0 9.1e-85 285.3 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EPS27845.1 - 6.7e-10 38.8 0.3 2.4e-09 37.0 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EPS27845.1 - 0.00046 19.4 0.2 0.00078 18.7 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EPS27845.1 - 0.0014 18.3 0.1 0.0024 17.6 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_13 PF13166.1 EPS27846.1 - 0.039 12.4 0.4 0.047 12.1 0.3 1.0 1 0 0 1 1 1 0 AAA domain DUF2357 PF09823.4 EPS27846.1 - 0.046 12.8 0.1 0.11 11.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) Tropomyosin_1 PF12718.2 EPS27846.1 - 0.12 12.1 1.6 1.1 9.1 0.8 2.2 1 1 1 2 2 2 0 Tropomyosin like CoA_transf_3 PF02515.12 EPS27847.1 - 4.8e-31 107.4 0.9 1.8e-30 105.6 0.1 2.1 3 0 0 3 3 3 1 CoA-transferase family III SnoaL_2 PF12680.2 EPS27848.1 - 0.022 15.1 0.0 0.031 14.6 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain SnoaL_4 PF13577.1 EPS27848.1 - 0.056 13.3 0.0 0.08 12.8 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain Ribosomal_S19e PF01090.14 EPS27849.1 - 2.6e-56 188.9 0.2 2.9e-56 188.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Abhydrolase_6 PF12697.2 EPS27850.1 - 2.3e-25 89.8 0.5 1.1e-24 87.6 0.2 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPS27850.1 - 3.5e-14 52.7 0.0 1.1e-13 51.1 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPS27850.1 - 2.3e-11 43.7 0.0 6.8e-09 35.6 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold DSPc PF00782.15 EPS27850.1 - 1.2e-10 41.0 0.0 2.4e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain FSH1 PF03959.8 EPS27850.1 - 0.00037 20.0 0.0 0.0062 15.9 0.0 2.2 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Thioesterase PF00975.15 EPS27850.1 - 0.00073 19.8 0.1 0.0014 18.8 0.1 1.4 1 0 0 1 1 1 1 Thioesterase domain Ser_hydrolase PF06821.8 EPS27850.1 - 0.0028 17.2 0.0 0.039 13.5 0.0 2.6 3 0 0 3 3 3 1 Serine hydrolase PGAP1 PF07819.8 EPS27850.1 - 0.0051 16.4 0.1 0.035 13.6 0.1 2.2 1 1 0 1 1 1 1 PGAP1-like protein DUF2305 PF10230.4 EPS27850.1 - 0.0091 15.4 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) PTPlike_phytase PF14566.1 EPS27850.1 - 0.011 15.8 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF1749 PF08538.5 EPS27850.1 - 0.015 14.2 0.0 0.71 8.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Y_phosphatase PF00102.22 EPS27850.1 - 0.052 12.8 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Hydrolase_4 PF12146.3 EPS27850.1 - 0.065 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Lipase_3 PF01764.20 EPS27850.1 - 0.069 12.7 0.8 0.15 11.6 0.1 1.8 1 1 1 2 2 2 0 Lipase (class 3) Abhydrolase_4 PF08386.5 EPS27850.1 - 0.07 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein LCAT PF02450.10 EPS27850.1 - 0.075 11.9 0.0 0.22 10.4 0.0 1.7 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase ILVD_EDD PF00920.16 EPS27851.1 - 1.7e-205 683.4 0.3 1.9e-205 683.2 0.2 1.0 1 0 0 1 1 1 1 Dehydratase family Pex2_Pex12 PF04757.9 EPS27852.1 - 3.7e-39 134.5 0.5 3.7e-39 134.5 0.4 1.4 2 0 0 2 2 2 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 EPS27852.1 - 0.0013 18.5 4.9 0.0027 17.5 3.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EPS27852.1 - 0.14 11.8 1.8 0.31 10.7 1.3 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPS27852.1 - 0.49 10.4 9.3 0.38 10.8 3.8 2.5 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Na_trans_assoc PF06512.8 EPS27852.1 - 1.5 8.7 3.8 1.7 8.5 0.5 2.0 1 1 1 2 2 2 0 Sodium ion transport-associated Phosphoesterase PF04185.9 EPS27853.1 - 9.9e-33 113.8 8.1 6.2e-32 111.2 5.6 2.0 1 1 0 1 1 1 1 Phosphoesterase family IBN_N PF03810.14 EPS27855.1 - 1.5e-12 47.2 0.0 1.6e-11 43.9 0.0 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EPS27855.1 - 0.0026 17.6 0.8 0.026 14.4 0.0 3.0 2 1 0 2 2 2 1 Exportin 1-like protein Cellulase PF00150.13 EPS27856.1 - 9.6e-16 57.7 1.6 9.6e-16 57.7 1.1 2.2 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_N PF02837.13 EPS27857.1 - 2e-29 102.2 0.4 1.2e-28 99.7 0.0 2.3 3 0 0 3 3 3 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EPS27857.1 - 2.9e-12 46.1 0.0 2.4e-11 43.1 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 EPS27857.1 - 2.3e-11 44.0 1.1 4.7e-11 43.1 0.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 EPS27857.1 - 0.0021 18.2 0.2 0.0058 16.8 0.2 1.7 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain Protoglobin PF11563.3 EPS27858.1 - 1.8e-54 183.6 0.2 2.3e-54 183.3 0.1 1.1 1 0 0 1 1 1 1 Protoglobin Aldedh PF00171.17 EPS27859.1 - 4.9e-136 453.7 0.5 5.9e-136 453.4 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EPS27859.1 - 6.7e-07 28.3 0.1 3.6e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) GPI-anchored PF10342.4 EPS27861.1 - 2.9e-21 75.7 0.1 2.9e-21 75.7 0.0 2.8 2 1 0 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Med3 PF11593.3 EPS27861.1 - 5.9 6.0 15.6 13 4.8 10.8 1.6 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal DUF624 PF04854.9 EPS27861.1 - 6.3 6.7 6.5 4.5 7.2 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function, DUF624 DUF2462 PF09495.5 EPS27862.1 - 2.4e-20 73.0 11.7 2.4e-20 73.0 8.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2462) Zn_clus PF00172.13 EPS27863.1 - 0.0059 16.4 10.8 0.014 15.3 7.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNA_helicase PF00910.17 EPS27863.1 - 0.17 12.0 0.1 3.4 7.8 0.0 2.7 3 0 0 3 3 3 0 RNA helicase SurE PF01975.12 EPS27864.1 - 7.3e-45 152.7 0.0 2e-44 151.2 0.0 1.6 2 0 0 2 2 2 1 Survival protein SurE Glyco_transf_28 PF03033.15 EPS27864.1 - 0.04 13.6 0.0 0.081 12.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain Glyco_trans_4_4 PF13579.1 EPS27864.1 - 0.043 13.9 0.1 0.16 12.1 0.0 1.9 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain DUF2888 PF11135.3 EPS27864.1 - 0.14 11.8 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2888) DUF2413 PF10310.4 EPS27865.1 - 5.7e-147 490.1 0.0 6.4e-147 489.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) CMD PF02627.15 EPS27867.1 - 7.7e-08 32.0 0.1 1.9e-06 27.6 0.1 2.5 2 1 0 2 2 2 1 Carboxymuconolactone decarboxylase family API5 PF05918.6 EPS27868.1 - 0.16 10.4 3.2 0.24 9.8 2.2 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) zf-C2H2_4 PF13894.1 EPS27869.1 - 0.036 14.3 4.6 0.21 12.0 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EPS27869.1 - 0.081 13.3 6.3 0.2 12.0 0.6 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type Tmemb_14 PF03647.8 EPS27871.1 - 4.8e-21 74.9 10.3 5.5e-21 74.7 7.1 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C UbiA PF01040.13 EPS27871.1 - 0.16 11.2 3.2 0.18 10.9 2.2 1.1 1 0 0 1 1 1 0 UbiA prenyltransferase family MFS_1 PF07690.11 EPS27872.1 - 2.3e-36 125.2 35.4 1.1e-32 113.1 10.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS27872.1 - 2.9e-10 39.3 9.3 2.1e-09 36.4 3.0 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 EPS27872.1 - 3.7e-08 32.1 13.0 3e-05 22.6 2.3 3.0 2 1 1 3 3 3 3 MFS/sugar transport protein MFS_3 PF05977.8 EPS27872.1 - 0.0028 15.8 3.3 0.0028 15.8 2.3 2.4 2 1 1 3 3 3 1 Transmembrane secretion effector ATG22 PF11700.3 EPS27872.1 - 0.0045 15.5 4.8 0.0045 15.5 3.3 3.5 2 2 1 3 3 3 2 Vacuole effluxer Atg22 like MFS_1_like PF12832.2 EPS27872.1 - 0.028 14.2 4.8 0.058 13.1 0.0 3.1 3 1 0 3 3 3 0 MFS_1 like family TFR_dimer PF04253.10 EPS27873.1 - 3.3e-17 62.2 0.0 5.9e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EPS27873.1 - 6.6e-17 61.8 0.0 1.2e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EPS27873.1 - 1.1e-06 28.2 0.0 3.2e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.10 EPS27873.1 - 0.032 13.4 0.0 0.058 12.6 0.0 1.3 1 0 0 1 1 1 0 Nicastrin RTC4 PF14474.1 EPS27874.1 - 2.2e-34 118.0 0.0 4e-34 117.2 0.0 1.4 1 0 0 1 1 1 1 RTC4-like domain DUF726 PF05277.7 EPS27875.1 - 8e-127 422.8 2.2 1.1e-126 422.4 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) PAT1 PF09770.4 EPS27876.1 - 5.1 5.2 18.3 7.7 4.6 12.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Fungal_trans PF04082.13 EPS27877.1 - 7.9e-08 31.4 0.0 1.4e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS27877.1 - 9.5e-05 22.2 12.5 0.00015 21.6 8.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MtrE PF04206.7 EPS27877.1 - 0.035 13.1 0.0 0.055 12.4 0.0 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit E p450 PF00067.17 EPS27880.1 - 2.6e-42 144.9 0.0 3.2e-42 144.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 LicD PF04991.8 EPS27882.1 - 4.2e-36 124.9 6.6 2e-35 122.7 4.6 1.9 1 1 0 1 1 1 1 LicD family Fungal_trans PF04082.13 EPS27883.1 - 1e-19 70.4 0.0 2.1e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS27883.1 - 2.5e-10 40.0 10.4 4.9e-10 39.1 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Apis_Csd PF11671.3 EPS27883.1 - 1.9 8.2 5.8 4 7.2 4.0 1.4 1 0 0 1 1 1 0 Complementary sex determiner protein Senescence PF06911.7 EPS27884.1 - 0.018 14.7 6.7 0.025 14.2 4.6 1.1 1 0 0 1 1 1 0 Senescence-associated protein SseC PF04888.7 EPS27884.1 - 3.3 6.9 8.8 4.2 6.5 6.1 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family DAD PF02109.11 EPS27885.1 - 4.3e-43 145.9 1.1 3.8e-42 142.8 0.8 1.9 1 1 0 1 1 1 1 DAD family TSP9 PF11493.3 EPS27885.1 - 0.16 12.5 0.6 15 6.2 0.3 2.5 1 1 1 2 2 2 0 Thylakoid soluble phosphoprotein TSP9 HA2 PF04408.18 EPS27886.1 - 1.1e-22 79.8 0.1 4.9e-22 77.8 0.0 2.2 3 0 0 3 3 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EPS27886.1 - 1.6e-20 72.9 0.0 1.2e-18 67.0 0.0 2.6 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EPS27886.1 - 3.2e-14 52.5 0.0 1.1e-13 50.8 0.0 2.0 2 0 0 2 2 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPS27886.1 - 8.5e-08 31.8 0.1 1.5e-06 27.8 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EPS27886.1 - 3.1e-05 24.1 0.1 8.7e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 EPS27886.1 - 0.0011 18.7 0.1 0.28 11.0 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 EPS27886.1 - 0.0021 17.8 0.1 0.0042 16.8 0.0 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain T2SE PF00437.15 EPS27886.1 - 0.0023 16.8 0.0 0.0059 15.5 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein SRP54 PF00448.17 EPS27886.1 - 0.0082 15.6 0.4 0.024 14.1 0.3 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_23 PF13476.1 EPS27886.1 - 0.013 15.8 0.3 0.11 12.8 0.0 2.6 3 1 0 3 3 3 0 AAA domain AAA_14 PF13173.1 EPS27886.1 - 0.017 15.0 0.1 0.14 12.1 0.1 2.3 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EPS27886.1 - 0.029 13.3 0.0 0.05 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) KaiC PF06745.8 EPS27886.1 - 0.029 13.4 0.0 0.053 12.6 0.0 1.4 1 0 0 1 1 1 0 KaiC Arch_ATPase PF01637.13 EPS27886.1 - 0.031 13.9 0.0 0.087 12.5 0.0 1.7 1 0 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 EPS27886.1 - 0.058 13.6 1.2 0.68 10.2 0.2 3.0 2 1 0 2 2 2 0 ABC transporter AAA_25 PF13481.1 EPS27886.1 - 0.064 12.6 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EPS27886.1 - 0.068 12.7 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.14 EPS27886.1 - 0.12 11.8 0.1 0.45 9.9 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 EPS27886.1 - 0.12 11.2 0.1 0.2 10.4 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.7 EPS27886.1 - 0.14 11.8 1.1 1 8.9 0.0 2.5 3 0 0 3 3 3 0 NACHT domain Prefoldin_2 PF01920.15 EPS27887.1 - 2.5e-24 85.0 5.8 2.9e-24 84.8 4.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit Tho2 PF11262.3 EPS27887.1 - 0.0028 16.7 1.3 0.0083 15.2 0.9 1.6 1 1 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 GAS PF13851.1 EPS27887.1 - 0.0059 15.8 6.8 0.0097 15.1 4.7 1.3 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF4200 PF13863.1 EPS27887.1 - 0.013 15.4 6.0 0.11 12.4 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DASH_Dad3 PF08656.5 EPS27887.1 - 0.023 14.3 3.5 0.049 13.3 0.4 2.1 2 0 0 2 2 2 0 DASH complex subunit Dad3 Dna2 PF08696.6 EPS27887.1 - 0.054 12.8 0.2 0.13 11.6 0.0 1.7 1 1 1 2 2 2 0 DNA replication factor Dna2 STAT_alpha PF01017.15 EPS27887.1 - 0.059 13.0 5.8 0.08 12.6 4.0 1.2 1 0 0 1 1 1 0 STAT protein, all-alpha domain Prefoldin PF02996.12 EPS27887.1 - 0.07 12.7 6.4 0.76 9.4 0.1 2.1 1 1 0 2 2 2 0 Prefoldin subunit p25-alpha PF05517.7 EPS27887.1 - 0.085 13.1 0.5 0.95 9.7 0.0 2.0 2 0 0 2 2 2 0 p25-alpha PMC2NT PF08066.7 EPS27887.1 - 0.3 11.3 1.7 2.3 8.5 0.1 2.1 1 1 1 2 2 2 0 PMC2NT (NUC016) domain ATP-synt_D PF01813.12 EPS27887.1 - 0.32 10.5 2.5 6.7 6.2 0.1 2.0 2 0 0 2 2 2 0 ATP synthase subunit D FliE PF02049.13 EPS27887.1 - 0.34 10.9 3.7 1.5 8.9 0.5 2.1 2 0 0 2 2 2 0 Flagellar hook-basal body complex protein FliE CENP-F_leu_zip PF10473.4 EPS27887.1 - 0.35 10.7 4.7 0.37 10.6 0.4 2.0 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2205 PF10224.4 EPS27887.1 - 1.5 8.4 6.6 0.18 11.3 0.9 1.9 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) IncA PF04156.9 EPS27887.1 - 2.2 7.8 8.8 6 6.4 6.1 1.7 1 1 0 1 1 1 0 IncA protein CBFD_NFYB_HMF PF00808.18 EPS27888.1 - 2.7e-29 100.9 0.9 3.8e-29 100.5 0.6 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EPS27888.1 - 1.1e-06 28.7 0.1 1.6e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 EPS27888.1 - 0.00071 19.3 0.0 0.001 18.8 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 EPS27888.1 - 0.0015 18.2 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 EPS27888.1 - 0.043 14.0 0.0 0.085 13.1 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Fungal_trans PF04082.13 EPS27889.1 - 5.1e-21 74.7 0.1 2e-20 72.7 0.0 1.9 1 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS27889.1 - 2.6e-09 36.8 11.1 3.9e-09 36.2 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_fiss_reg PF05308.6 EPS27889.1 - 8.7 5.6 13.4 0.59 9.4 5.4 1.8 2 0 0 2 2 2 0 Mitochondrial fission regulator TatD_DNase PF01026.16 EPS27890.1 - 2.9e-35 121.7 0.0 6.1e-35 120.6 0.0 1.4 1 1 0 1 1 1 1 TatD related DNase Abhydrolase_6 PF12697.2 EPS27892.1 - 2.4e-24 86.5 4.5 2.4e-24 86.5 3.1 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPS27892.1 - 5.7e-17 62.0 0.0 2.4e-13 50.1 0.0 2.6 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPS27892.1 - 2.8e-11 43.3 0.0 2.7e-09 36.9 0.0 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.15 EPS27892.1 - 0.00013 21.5 0.0 0.00029 20.3 0.0 1.5 1 0 0 1 1 1 1 Putative esterase DUF915 PF06028.6 EPS27892.1 - 0.00014 21.0 0.0 0.00026 20.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Chlorophyllase2 PF12740.2 EPS27892.1 - 0.0047 15.8 0.0 0.0068 15.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_2 PF02230.11 EPS27892.1 - 0.0074 15.7 0.1 0.35 10.2 0.0 2.9 3 1 0 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 EPS27892.1 - 0.011 15.3 0.0 0.032 13.8 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Thioesterase PF00975.15 EPS27892.1 - 0.012 15.8 0.3 0.095 12.9 0.2 2.5 1 1 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.20 EPS27892.1 - 0.042 13.4 0.0 0.088 12.4 0.0 1.5 2 0 0 2 2 2 0 Lipase (class 3) Hydrolase_4 PF12146.3 EPS27892.1 - 0.11 12.3 0.1 0.6 10.0 0.0 2.2 2 0 0 2 2 2 0 Putative lysophospholipase Chlorophyllase PF07224.6 EPS27892.1 - 0.13 10.9 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Spo7 PF03907.8 EPS27893.1 - 2.1e-68 230.0 0.0 2.7e-68 229.6 0.0 1.1 1 0 0 1 1 1 1 Spo7-like protein Cupin_2 PF07883.6 EPS27894.1 - 4.4e-21 74.1 0.3 2.1e-10 39.9 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EPS27894.1 - 6e-16 57.5 1.6 6e-12 44.7 0.2 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF861) CENP-C_C PF11699.3 EPS27894.1 - 4.4e-05 23.3 0.0 0.00013 21.8 0.0 1.7 2 0 0 2 2 2 1 Mif2/CENP-C like AraC_binding PF02311.14 EPS27894.1 - 0.00011 21.8 0.1 0.029 14.0 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_1 PF00190.17 EPS27894.1 - 0.00096 18.6 0.0 0.013 14.9 0.0 2.4 1 1 0 1 1 1 1 Cupin Cupin_6 PF12852.2 EPS27894.1 - 0.0025 17.4 0.0 0.3 10.6 0.0 2.1 1 1 1 2 2 2 2 Cupin MCM PF00493.18 EPS27895.1 - 7.9e-130 432.4 0.3 1.1e-129 431.9 0.2 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EPS27895.1 - 4.8e-16 59.3 0.0 1.3e-15 57.9 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EPS27895.1 - 4.6e-07 29.1 0.0 6.1e-06 25.5 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EPS27895.1 - 0.0055 16.3 0.0 0.013 15.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EPS27895.1 - 0.054 12.9 0.0 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain RAP1 PF07218.6 EPS27895.1 - 5 5.0 6.9 7.4 4.5 4.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PPR_3 PF13812.1 EPS27896.1 - 9.4e-17 59.8 10.9 0.00025 21.1 0.0 11.0 12 0 0 12 12 12 4 Pentatricopeptide repeat domain PPR_2 PF13041.1 EPS27896.1 - 5.2e-14 51.9 2.9 6.3e-10 38.8 0.0 6.2 6 2 2 8 8 8 1 PPR repeat family PPR PF01535.15 EPS27896.1 - 5.7e-12 44.7 1.6 0.002 17.9 0.0 8.0 10 0 0 10 10 10 2 PPR repeat PPR_1 PF12854.2 EPS27896.1 - 2.3e-08 33.3 0.0 0.2 11.1 0.0 5.7 6 0 0 6 6 6 2 PPR repeat TPR_14 PF13428.1 EPS27896.1 - 0.3 11.8 16.5 5 8.0 0.0 8.2 8 1 1 9 9 9 0 Tetratricopeptide repeat TPR_2 PF07719.12 EPS27897.1 - 0.027 14.3 0.1 0.12 12.3 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat p450 PF00067.17 EPS27898.1 - 1.5e-54 185.2 0.0 2.1e-54 184.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Rhodanese PF00581.15 EPS27899.1 - 2.8e-13 50.2 0.0 4.4e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain GTP_EFTU PF00009.22 EPS27900.1 - 4.3e-32 111.0 0.0 2.9e-31 108.3 0.0 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EPS27900.1 - 1.8e-19 69.5 0.1 5.2e-19 68.1 0.1 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EPS27900.1 - 8.1e-13 48.2 0.6 4.1e-10 39.6 0.0 3.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EPS27900.1 - 6.3e-06 26.1 0.0 2.3e-05 24.3 0.0 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EPS27900.1 - 0.00021 20.8 0.1 0.00063 19.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 EPS27900.1 - 0.0039 17.6 0.2 0.025 15.0 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein ATP_bind_1 PF03029.12 EPS27900.1 - 0.006 16.1 0.0 0.015 14.8 0.0 1.8 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 EPS27900.1 - 0.047 13.8 0.0 0.19 11.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain MMS1_N PF10433.4 EPS27901.1 - 1.1e-113 380.0 0.0 1.7e-113 379.4 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 EPS27901.1 - 6.6e-08 31.9 0.0 3.1e-06 26.4 0.0 2.5 2 0 0 2 2 2 1 CPSF A subunit region Abhydrolase_7 PF12715.2 EPS27901.1 - 0.17 10.7 0.0 0.29 10.0 0.0 1.2 1 0 0 1 1 1 0 Abhydrolase family RabGAP-TBC PF00566.13 EPS27902.1 - 1.4e-27 96.5 0.3 2.1e-27 96.0 0.2 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Yip1 PF04893.12 EPS27903.1 - 3.6e-15 55.8 14.3 4.7e-15 55.5 9.9 1.1 1 0 0 1 1 1 1 Yip1 domain Ribosomal_L40e PF01020.12 EPS27904.1 - 1.5e-29 101.3 11.6 2.7e-29 100.5 8.0 1.4 1 0 0 1 1 1 1 Ribosomal L40e family ubiquitin PF00240.18 EPS27904.1 - 1.6e-27 94.6 1.4 1.3e-26 91.7 0.4 2.3 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 EPS27904.1 - 2e-12 46.6 0.3 5.5e-12 45.1 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EPS27904.1 - 0.0068 16.6 0.1 0.02 15.1 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.4 EPS27904.1 - 0.081 13.1 0.0 0.23 11.6 0.0 1.8 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain eIF-5a PF01287.15 EPS27905.1 - 4.9e-26 90.4 1.5 7.2e-26 89.9 1.1 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 EPS27905.1 - 5.8e-05 22.6 0.8 5.8e-05 22.6 0.6 1.8 2 0 0 2 2 2 1 KOW motif EFP_N PF08207.7 EPS27905.1 - 0.012 15.4 0.2 0.029 14.2 0.0 1.7 2 0 0 2 2 2 0 Elongation factor P (EF-P) KOW-like domain Vps52 PF04129.7 EPS27906.1 - 1.1e-120 403.6 0.1 1.4e-120 403.2 0.1 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.4 EPS27906.1 - 1.4e-06 26.7 0.3 2.2e-06 26.1 0.2 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 IncA PF04156.9 EPS27906.1 - 0.00046 19.8 2.9 0.00057 19.5 0.4 2.1 2 0 0 2 2 2 1 IncA protein BicD PF09730.4 EPS27906.1 - 0.001 17.5 2.3 0.0015 17.0 1.6 1.1 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D Sec8_exocyst PF04048.9 EPS27906.1 - 0.0092 15.6 0.5 0.026 14.1 0.3 1.7 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain V_ATPase_I PF01496.14 EPS27906.1 - 0.23 9.2 3.1 0.32 8.7 2.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PLC-beta_C PF08703.5 EPS27906.1 - 0.25 11.0 2.7 1.1 8.9 0.8 2.3 2 0 0 2 2 2 0 PLC-beta C terminal Baculo_PEP_C PF04513.7 EPS27906.1 - 6.7 6.5 6.2 3 7.6 0.3 2.9 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DAO PF01266.19 EPS27907.1 - 1.7e-55 188.3 0.2 2e-55 188.1 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPS27907.1 - 1.6e-06 27.9 0.1 4.7e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EPS27907.1 - 0.00012 22.2 0.0 0.00023 21.2 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EPS27907.1 - 0.00097 18.3 1.4 0.0081 15.2 1.0 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EPS27907.1 - 0.0039 16.3 0.1 0.078 12.0 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 EPS27907.1 - 0.012 15.3 0.2 0.25 11.1 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 EPS27907.1 - 0.019 14.0 0.5 0.14 11.2 0.0 2.4 3 0 0 3 3 3 0 Thi4 family Pyr_redox PF00070.22 EPS27907.1 - 0.04 14.3 0.8 0.18 12.2 0.1 2.2 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPS27907.1 - 0.077 12.8 0.1 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EPS27907.1 - 0.1 11.4 2.2 0.86 8.3 1.6 1.9 1 1 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.14 EPS27907.1 - 0.1 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.20 EPS27907.1 - 0.11 12.4 0.5 0.22 11.4 0.4 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Fungal_trans PF04082.13 EPS27908.1 - 3.1e-15 55.7 0.8 1.1e-14 53.9 0.6 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EPS27908.1 - 1.9e-08 34.1 18.3 0.00065 19.8 4.9 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPS27908.1 - 1.2e-05 25.2 15.4 0.0079 16.4 3.8 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EPS27908.1 - 2.4e-05 24.3 7.9 2.4e-05 24.3 5.5 3.5 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 EPS27908.1 - 0.00097 18.9 15.4 0.0073 16.1 0.2 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger DUF4035 PF13227.1 EPS27908.1 - 0.066 12.5 0.1 0.19 11.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4035) XPA_N PF01286.13 EPS27908.1 - 1.6 8.4 4.7 15 5.3 0.1 3.1 3 0 0 3 3 3 0 XPA protein N-terminal zf-C2H2_jaz PF12171.3 EPS27908.1 - 2.8 8.2 15.2 0.36 11.0 3.1 2.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Zn_ribbon_recom PF13408.1 EPS27908.1 - 7.2 6.9 6.5 14 6.0 4.5 1.4 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain SET PF00856.23 EPS27909.1 - 1.5e-11 44.8 0.1 5.9e-09 36.4 0.1 2.3 2 0 0 2 2 2 2 SET domain DUF4237 PF14021.1 EPS27910.1 - 1.3e-33 115.0 0.1 2.1e-33 114.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4237) NAD_binding_10 PF13460.1 EPS27911.1 - 3.7e-28 98.7 0.0 4.6e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPS27911.1 - 6.1e-08 32.3 0.0 1.2e-07 31.4 0.0 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EPS27911.1 - 2.7e-07 30.0 0.3 8.6e-07 28.4 0.1 1.9 2 1 0 2 2 2 1 NmrA-like family TrkA_N PF02254.13 EPS27911.1 - 1e-05 25.5 0.0 2.4e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 TrkA-N domain NAD_binding_4 PF07993.7 EPS27911.1 - 3.5e-05 22.8 0.1 0.062 12.2 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein ApbA PF02558.11 EPS27911.1 - 0.0014 18.1 0.0 0.002 17.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DapB_N PF01113.15 EPS27911.1 - 0.013 15.4 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_2 PF03446.10 EPS27911.1 - 0.078 12.8 0.1 0.25 11.1 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short PF00106.20 EPS27911.1 - 0.11 12.3 0.2 0.58 10.0 0.1 2.1 2 1 0 2 2 2 0 short chain dehydrogenase Fungal_trans PF04082.13 EPS27912.1 - 2.2e-14 52.9 0.2 4e-14 52.1 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS27912.1 - 1.4e-06 28.0 17.5 3.8e-06 26.6 12.1 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M24 PF00557.19 EPS27913.1 - 2e-43 148.3 0.0 2.7e-43 147.9 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 MIP-T3 PF10243.4 EPS27913.1 - 0.55 8.6 6.3 0.71 8.2 4.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 RRM_1 PF00076.17 EPS27914.1 - 8.7e-82 268.7 5.5 2.8e-21 74.9 0.2 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS27914.1 - 2.6e-53 177.8 1.3 2e-13 50.1 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS27914.1 - 2.1e-41 139.5 0.3 3.1e-08 33.3 0.1 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EPS27914.1 - 1.2e-32 111.4 2.3 3.3e-32 109.9 0.7 2.6 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain Nup35_RRM_2 PF14605.1 EPS27914.1 - 2.5e-05 23.9 0.2 8.7 6.1 0.0 4.4 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif CbiG_mid PF11761.3 EPS27914.1 - 0.0011 19.1 6.1 0.64 10.2 0.0 4.1 5 0 0 5 5 5 2 Cobalamin biosynthesis central region Limkain-b1 PF11608.3 EPS27914.1 - 0.0052 16.5 4.9 5.1 6.9 0.1 3.7 3 0 0 3 3 3 1 Limkain b1 OB_RNB PF08206.6 EPS27914.1 - 0.013 14.9 1.6 6.8 6.2 0.0 3.6 3 0 0 3 3 3 0 Ribonuclease B OB domain HECT PF00632.20 EPS27915.1 - 1e-85 287.7 0.0 1.6e-85 287.0 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 EPS27915.1 - 0.0012 18.2 3.1 0.004 16.6 2.1 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif MRP-L27 PF09809.4 EPS27916.1 - 1e-14 54.0 0.1 1.3e-14 53.7 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Ribosomal_L14e PF01929.12 EPS27916.1 - 0.073 13.4 0.0 0.18 12.1 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L14 Utp14 PF04615.8 EPS27917.1 - 1.7e-215 717.4 73.3 1.7e-215 717.4 50.8 2.0 1 1 1 2 2 2 1 Utp14 protein DUF4054 PF13262.1 EPS27917.1 - 0.12 12.6 2.0 0.2 11.9 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4054) Glyco_hydro_81 PF03639.8 EPS27918.1 - 1.5e-204 680.9 2.0 1.9e-204 680.6 1.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Metallophos_2 PF12850.2 EPS27919.1 - 5.7e-10 39.2 0.0 1.2e-09 38.1 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EPS27919.1 - 5.2e-08 32.5 0.9 0.00093 18.6 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase RVT_3 PF13456.1 EPS27919.1 - 0.068 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase-like Ribosomal_S8e PF01201.17 EPS27920.1 - 3.6e-47 159.8 2.8 4.2e-47 159.6 1.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e SMAP PF15477.1 EPS27920.1 - 0.11 12.7 1.5 0.36 11.1 1.0 2.1 1 1 0 1 1 1 0 Small acidic protein family DUF2470 PF10615.4 EPS27921.1 - 4.1e-18 65.3 0.1 5.5e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DPM2 PF07297.7 EPS27921.1 - 5.9 7.2 10.5 12 6.2 1.8 2.5 1 1 1 2 2 2 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) TFIIF_alpha PF05793.7 EPS27922.1 - 0.46 8.7 22.5 0.51 8.6 15.6 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FRQ PF09421.5 EPS27922.1 - 2.9 5.5 14.1 3.5 5.2 9.8 1.1 1 0 0 1 1 1 0 Frequency clock protein Cwf_Cwc_15 PF04889.7 EPS27922.1 - 8 6.0 23.2 11 5.5 16.1 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nucleo_P87 PF07267.6 EPS27922.1 - 8.5 4.9 14.1 13 4.3 9.8 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 SPX PF03105.14 EPS27924.1 - 1.3e-46 159.6 0.0 1.8e-46 159.1 0.0 1.2 1 0 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 EPS27924.1 - 6.6e-30 104.3 39.8 9.6e-30 103.8 27.6 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EPS27924.1 - 4.5e-13 48.5 43.8 3.5e-12 45.5 16.9 2.3 1 1 1 2 2 2 2 Citrate transporter MEDS PF14417.1 EPS27924.1 - 0.041 12.9 0.2 0.088 11.8 0.0 1.6 2 0 0 2 2 2 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Ribosomal_S7 PF00177.16 EPS27925.1 - 1.1e-24 86.7 0.0 2.2e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e F-box PF00646.28 EPS27926.1 - 1.1e-05 24.9 0.0 2.2e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EPS27926.1 - 4e-05 23.2 0.2 0.0001 21.9 0.1 1.7 1 0 0 1 1 1 1 F-box-like SRP40_C PF05022.7 EPS27927.1 - 2.5e-22 79.1 0.7 8.8e-22 77.4 0.5 2.0 1 0 0 1 1 1 1 SRP40, C-terminal domain Utp14 PF04615.8 EPS27927.1 - 0.45 8.6 49.2 0.55 8.3 34.1 1.2 1 0 0 1 1 1 0 Utp14 protein Sec3_C PF09763.4 EPS27928.1 - 1.4e-210 701.0 0.0 1.8e-210 700.6 0.0 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 EPS27928.1 - 5.3e-29 99.9 0.0 1e-28 99.0 0.0 1.5 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.1 EPS27928.1 - 0.099 12.7 0.2 0.26 11.4 0.1 1.7 1 0 0 1 1 1 0 Sec3 exocyst complex subunit Vps52 PF04129.7 EPS27928.1 - 0.11 10.9 0.3 0.19 10.1 0.2 1.3 1 0 0 1 1 1 0 Vps52 / Sac2 family DOCK-C2 PF14429.1 EPS27929.1 - 6.5e-34 117.1 0.0 1.1e-33 116.4 0.0 1.4 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 EPS27929.1 - 8.5e-12 44.7 0.0 2.5e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 Dedicator of cytokinesis SH3_1 PF00018.23 EPS27929.1 - 4.7e-05 22.6 0.0 9.5e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EPS27929.1 - 0.00034 20.1 0.0 0.0025 17.3 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain Ofd1_CTDD PF10637.4 EPS27929.1 - 0.023 13.8 0.0 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term Ribosomal_S19 PF00203.16 EPS27929.1 - 0.055 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein S19 CD47 PF04549.9 EPS27929.1 - 0.54 10.2 0.1 1 9.3 0.1 1.3 1 0 0 1 1 1 0 CD47 transmembrane region Na_Ca_ex PF01699.19 EPS27931.1 - 1.6e-44 150.8 34.9 9.9e-23 80.2 8.9 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein p450 PF00067.17 EPS27932.1 - 1.1e-52 179.0 0.0 1.6e-52 178.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CHCH PF06747.8 EPS27933.1 - 0.0021 17.9 0.8 0.0029 17.4 0.6 1.2 1 0 0 1 1 1 1 CHCH domain Cid2 PF09774.4 EPS27933.1 - 0.032 14.3 0.1 0.037 14.1 0.1 1.1 1 0 0 1 1 1 0 Caffeine-induced death protein 2 Cmc1 PF08583.5 EPS27933.1 - 0.097 12.4 1.5 0.13 12.0 1.1 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF1992 PF09350.5 EPS27934.1 - 7.2e-25 86.6 0.3 1.9e-24 85.2 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) GLYCAM-1 PF05242.6 EPS27936.1 - 0.088 12.7 0.8 0.18 11.6 0.6 1.5 1 0 0 1 1 1 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) P5CR_dimer PF14748.1 EPS27937.1 - 1.1e-18 67.1 0.4 1.1e-17 63.9 0.1 2.2 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EPS27937.1 - 2.1e-07 31.2 0.1 5.4e-07 29.9 0.1 1.8 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.10 EPS27938.1 - 8.9e-13 47.6 0.0 1.2e-10 40.6 0.0 3.2 2 1 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 EPS27938.1 - 1e-05 25.6 0.0 3.8e-05 23.7 0.0 1.9 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Acetyltransf_8 PF13523.1 EPS27939.1 - 6.1e-50 169.0 0.1 8.9e-50 168.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EPS27939.1 - 0.00055 20.1 0.0 0.00094 19.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EPS27939.1 - 0.13 12.2 0.0 0.87 9.5 0.0 2.2 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain ERG2_Sigma1R PF04622.7 EPS27940.1 - 4.5e-95 316.9 0.5 5.1e-95 316.8 0.4 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein DUF3125 PF11323.3 EPS27941.1 - 0.048 13.4 0.1 0.086 12.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3125) Glyco_hydro_12 PF01670.11 EPS27942.1 - 3.8e-36 124.2 2.0 3.8e-36 124.2 1.4 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 zf-C2H2 PF00096.21 EPS27943.1 - 0.0035 17.5 0.0 0.0066 16.7 0.0 1.4 1 0 0 1 1 1 1 Zinc finger, C2H2 type DUF3505 PF12013.3 EPS27943.1 - 0.019 15.1 0.0 0.028 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3505) zf-C2H2_4 PF13894.1 EPS27943.1 - 0.023 14.9 0.1 0.066 13.5 0.0 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger VP4_2 PF08935.5 EPS27944.1 - 0.1 13.2 0.1 0.14 12.7 0.0 1.1 1 0 0 1 1 1 0 Viral protein VP4 subunit Cyclin_N PF00134.18 EPS27945.1 - 4.8e-11 42.3 0.0 2.2e-10 40.1 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin PF08613.6 EPS27945.1 - 4.3e-10 40.1 0.0 8.4e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Cyclin Amidohydro_2 PF04909.9 EPS27946.1 - 8.5e-33 114.0 0.0 1e-32 113.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.16 EPS27946.1 - 0.00027 20.2 0.0 0.00042 19.5 0.0 1.4 1 0 0 1 1 1 1 TatD related DNase Raptor_N PF14538.1 EPS27947.1 - 0.027 14.3 0.6 0.12 12.1 0.4 2.0 1 1 0 1 1 1 0 Raptor N-terminal CASPase like domain ATP_bind_3 PF01171.15 EPS27948.1 - 3.8e-19 68.8 0.0 6.4e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 PP-loop family RecR PF02132.10 EPS27948.1 - 0.00043 19.6 1.8 0.00043 19.6 1.2 2.5 3 0 0 3 3 3 1 RecR protein tRNA_Me_trans PF03054.11 EPS27948.1 - 0.037 12.5 0.0 0.062 11.8 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase DUF2392 PF10288.4 EPS27948.1 - 0.052 13.8 0.0 0.12 12.7 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2392) zf-UBR PF02207.15 EPS27948.1 - 0.2 11.3 6.1 3.1 7.5 0.5 2.5 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) RasGEF PF00617.14 EPS27949.1 - 2.9e-45 154.3 1.1 4.7e-45 153.6 0.8 1.3 1 0 0 1 1 1 1 RasGEF domain Complex1_LYR_2 PF13233.1 EPS27949.1 - 9.5e-18 64.6 0.1 5.5e-17 62.1 0.0 2.2 2 0 0 2 2 2 1 Complex1_LYR-like RasGEF_N PF00618.15 EPS27949.1 - 1.5e-13 50.7 0.0 3.7e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif Miro PF08477.8 EPS27949.1 - 3.6e-07 30.6 0.0 1.1e-06 29.1 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 EPS27949.1 - 0.028 13.8 0.0 5.8 6.3 0.0 2.7 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EPS27949.1 - 0.14 12.0 0.0 1.3 9.0 0.0 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase zf-HIT PF04438.11 EPS27951.1 - 1.4e-08 34.2 8.0 2.2e-08 33.5 5.5 1.3 1 0 0 1 1 1 1 HIT zinc finger Nfu_N PF08712.6 EPS27952.1 - 2.3e-29 100.8 0.0 1.4e-28 98.2 0.0 2.1 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 EPS27952.1 - 1.1e-22 79.5 0.2 2e-22 78.7 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain PI31_Prot_C PF08577.6 EPS27952.1 - 0.057 14.0 0.1 0.13 12.9 0.1 1.5 1 0 0 1 1 1 0 PI31 proteasome regulator PSP1 PF04468.7 EPS27954.1 - 6.6e-30 102.9 1.4 1.2e-29 102.0 1.0 1.5 1 0 0 1 1 1 1 PSP1 C-terminal conserved region Rotavirus_VP3 PF06929.6 EPS27954.1 - 0.33 8.7 0.5 0.47 8.2 0.3 1.1 1 0 0 1 1 1 0 Rotavirus VP3 protein Sugar_tr PF00083.19 EPS27955.1 - 4.1e-82 276.1 19.3 4.7e-82 275.9 13.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS27955.1 - 1.2e-32 113.0 49.9 9.1e-27 93.6 17.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EPS27955.1 - 3.6e-05 22.1 2.0 3.6e-05 22.1 1.4 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.13 EPS27956.1 - 3.3e-12 45.8 0.0 7.8e-12 44.6 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS27956.1 - 1.2e-09 37.9 10.2 2.1e-09 37.1 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_88 PF07470.8 EPS27957.1 - 3e-09 36.3 0.3 1e-08 34.6 0.2 1.8 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 DUF2264 PF10022.4 EPS27958.1 - 1.8e-127 424.9 0.0 2.2e-127 424.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) FRG1 PF06229.7 EPS27959.1 - 3.4e-60 202.7 0.0 5.3e-60 202.1 0.0 1.3 1 0 0 1 1 1 1 FRG1-like family Fascin PF06268.8 EPS27959.1 - 0.011 15.8 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 0 Fascin domain Glyco_hydro_3 PF00933.16 EPS27960.1 - 5.7e-89 298.0 0.0 8e-89 297.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EPS27960.1 - 3.7e-43 147.6 0.1 8.7e-43 146.4 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EPS27960.1 - 5e-22 77.6 0.1 1.2e-21 76.3 0.0 1.7 2 0 0 2 2 2 1 Fibronectin type III-like domain HECT PF00632.20 EPS27961.1 - 8.3e-74 248.5 0.0 1.2e-73 248.0 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ribosomal_L15e PF00827.12 EPS27962.1 - 8e-90 299.5 12.1 9.1e-90 299.3 8.4 1.0 1 0 0 1 1 1 1 Ribosomal L15 zf-RING_2 PF13639.1 EPS27963.1 - 6.9e-14 51.4 8.8 6.9e-14 51.4 6.1 1.7 2 0 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.2 EPS27963.1 - 2.8e-08 33.7 5.5 5.8e-08 32.7 3.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EPS27963.1 - 1.8e-07 31.0 7.6 1.8e-07 31.0 5.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPS27963.1 - 5.8e-07 29.0 5.5 1.3e-06 27.9 3.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPS27963.1 - 9.5e-06 25.1 6.0 2e-05 24.1 4.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPS27963.1 - 3.6e-05 23.3 6.4 7.8e-05 22.3 4.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EPS27963.1 - 0.0015 18.3 4.1 0.0015 18.3 2.9 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H_2 PF13832.1 EPS27963.1 - 0.072 13.0 2.0 0.16 11.9 1.4 1.5 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_UBOX PF13445.1 EPS27963.1 - 0.58 9.9 4.0 1.4 8.6 2.8 1.7 1 0 0 1 1 1 0 RING-type zinc-finger RINGv PF12906.2 EPS27963.1 - 0.64 10.1 7.6 1.5 8.9 5.2 1.7 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.1 EPS27963.1 - 0.78 9.6 10.5 0.081 12.8 3.3 2.3 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 EPS27963.1 - 0.93 9.0 4.8 2.2 7.8 3.4 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.3 EPS27963.1 - 0.99 9.4 6.6 5.6 7.0 4.6 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 EPS27963.1 - 2.5 7.7 5.5 4.5 6.9 3.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Ada3 PF10198.4 EPS27964.1 - 2.6e-40 137.1 0.9 6.4e-40 135.9 0.6 1.7 1 0 0 1 1 1 1 Histone acetyltransferases subunit 3 NPR2 PF06218.6 EPS27965.1 - 1.3e-130 435.9 0.0 1e-129 433.0 0.0 1.9 2 0 0 2 2 2 1 Nitrogen permease regulator 2 DUF4250 PF14056.1 EPS27965.1 - 0.1 12.3 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) Afi1 PF07792.7 EPS27965.1 - 0.12 12.3 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking NPR3 PF03666.8 EPS27965.1 - 0.22 10.0 0.2 14 4.0 0.0 2.8 2 1 1 3 3 3 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF1656 PF07869.7 EPS27966.1 - 0.34 10.7 2.1 0.59 9.9 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) Lactamase_B_2 PF12706.2 EPS27967.1 - 8.8e-10 38.4 0.0 2.4e-09 37.0 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EPS27967.1 - 2.9e-09 36.8 0.1 5.4e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DRMBL PF07522.9 EPS27967.1 - 0.00016 21.6 0.0 0.006 16.6 0.0 2.6 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase Sporozoite_P67 PF05642.6 EPS27967.1 - 0.0031 15.4 6.1 0.0052 14.7 4.2 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Nop14 PF04147.7 EPS27967.1 - 0.16 9.8 21.2 0.26 9.1 14.7 1.3 1 0 0 1 1 1 0 Nop14-like family BSP_II PF05432.6 EPS27967.1 - 1.4 8.1 17.4 0.037 13.2 7.4 1.7 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) PRP21_like_P PF12230.3 EPS27967.1 - 1.7 8.0 15.5 1.3 8.4 5.1 2.1 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein RRN3 PF05327.6 EPS27967.1 - 3.2 5.7 7.2 4.9 5.1 5.0 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TFIIA PF03153.8 EPS27967.1 - 3.6 7.3 19.3 6 6.6 13.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RNA_pol_3_Rpc31 PF11705.3 EPS27967.1 - 4.8 7.0 20.3 11 5.8 14.1 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 TRAP_alpha PF03896.11 EPS27967.1 - 6.4 5.6 10.7 13 4.6 7.4 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Amidohydro_1 PF01979.15 EPS27968.1 - 3.4e-61 207.7 3.1 2e-60 205.2 1.7 2.1 2 0 0 2 2 2 1 Amidohydrolase family Urease_alpha PF00449.15 EPS27968.1 - 3.5e-56 188.5 0.9 6.4e-56 187.7 0.6 1.4 1 0 0 1 1 1 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 EPS27968.1 - 1.4e-40 137.1 0.2 1.7e-39 133.6 0.0 2.3 2 0 0 2 2 2 1 Urease beta subunit Urease_gamma PF00547.13 EPS27968.1 - 7.3e-34 115.7 0.1 1.7e-33 114.5 0.0 1.6 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_5 PF13594.1 EPS27968.1 - 4.1e-07 29.7 3.8 1.2e-06 28.1 1.8 2.3 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EPS27968.1 - 3.3e-06 26.5 0.6 0.00032 20.0 0.0 2.9 3 0 0 3 3 3 1 Amidohydrolase family HMG_box PF00505.14 EPS27969.1 - 1.3e-11 44.5 2.8 2.6e-11 43.6 2.0 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EPS27969.1 - 6.2e-08 32.8 2.7 1.3e-07 31.8 1.9 1.6 1 0 0 1 1 1 1 HMG-box domain KRAB PF01352.22 EPS27969.1 - 0.021 14.2 0.2 0.035 13.5 0.1 1.3 1 0 0 1 1 1 0 KRAB box NAD_binding_1 PF00175.16 EPS27970.1 - 4.5e-31 107.6 0.0 6.6e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EPS27970.1 - 1.1e-22 80.0 0.0 3.1e-22 78.5 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EPS27970.1 - 1.6e-08 34.5 0.0 8.6e-05 22.4 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain B12D PF06522.6 EPS27970.1 - 0.019 14.6 0.1 2 8.1 0.0 2.4 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit FAD_binding_9 PF08021.6 EPS27970.1 - 0.058 13.3 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Ribosomal_L18ae PF01775.12 EPS27971.1 - 8e-60 200.2 0.3 1e-59 199.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain PCI PF01399.22 EPS27972.1 - 3.4e-10 40.1 0.0 7.3e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 PCI domain DUF433 PF04255.9 EPS27972.1 - 0.029 13.8 0.0 0.061 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF433) Peptidase_M76 PF09768.4 EPS27972.1 - 0.091 12.2 0.2 0.25 10.7 0.0 1.8 2 0 0 2 2 2 0 Peptidase M76 family BTB PF00651.26 EPS27973.1 - 0.00014 21.7 0.0 0.00028 20.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain CLTH PF10607.4 EPS27974.1 - 1.1e-31 109.4 0.1 3e-31 108.0 0.0 1.7 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 EPS27974.1 - 1.6e-18 66.1 0.6 4.4e-18 64.7 0.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.7 EPS27974.1 - 1e-05 24.8 0.0 2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_2 PF13639.1 EPS27974.1 - 0.00011 21.9 0.2 0.0002 21.1 0.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EPS27974.1 - 0.00015 21.3 0.2 0.00029 20.4 0.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EPS27974.1 - 0.0016 18.4 0.6 0.0028 17.6 0.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPS27974.1 - 0.0051 16.4 0.5 0.0083 15.7 0.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Syntaxin PF00804.20 EPS27974.1 - 0.011 15.9 0.5 0.011 15.9 0.4 2.4 3 1 0 3 3 3 0 Syntaxin FANCAA PF15146.1 EPS27974.1 - 0.012 14.5 0.1 0.019 13.8 0.1 1.3 1 0 0 1 1 1 0 Fanconi anemia-associated zf-C3HC4 PF00097.20 EPS27974.1 - 0.028 14.0 0.4 0.053 13.1 0.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Flagellin_C PF00700.16 EPS27974.1 - 0.065 13.3 0.5 0.2 11.8 0.3 1.8 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region Corona_S2 PF01601.11 EPS27974.1 - 0.1 10.7 1.2 0.14 10.2 0.9 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein zf-C3HC4_4 PF15227.1 EPS27974.1 - 0.11 12.3 0.8 0.28 11.0 0.5 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Nsp1_C PF05064.8 EPS27975.1 - 0.026 14.1 0.2 0.072 12.7 0.1 1.7 1 0 0 1 1 1 0 Nsp1-like C-terminal region zf-Tim10_DDP PF02953.10 EPS27976.1 - 6.1e-25 86.3 0.8 7e-25 86.1 0.6 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 EPS27976.1 - 0.12 11.8 1.0 0.15 11.4 0.7 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) tRNA-synt_2 PF00152.15 EPS27977.1 - 3e-72 243.2 0.0 3.7e-72 242.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EPS27977.1 - 8.4e-10 38.3 0.0 1.5e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EPS27977.1 - 4.4e-07 29.3 0.1 0.00021 20.5 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EPS27977.1 - 0.0035 16.9 0.0 1.2 8.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_anti_2 PF13742.1 EPS27977.1 - 0.015 15.1 0.0 0.22 11.3 0.0 1.9 1 1 1 2 2 2 0 OB-fold nucleic acid binding domain 2OG-FeII_Oxy PF03171.15 EPS27978.1 - 0.0013 18.9 0.0 0.0035 17.6 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Clr2 PF10383.4 EPS27979.1 - 3.2e-24 85.4 0.0 6e-24 84.6 0.0 1.5 1 0 0 1 1 1 1 Transcription-silencing protein Clr2 ABC_membrane_2 PF06472.10 EPS27980.1 - 8.1e-92 307.3 0.0 1.5e-91 306.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EPS27980.1 - 1.2e-13 51.4 0.0 2.3e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter RuvB_N PF05496.7 EPS27980.1 - 0.023 13.7 0.0 0.059 12.4 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_29 PF13555.1 EPS27980.1 - 0.03 13.8 0.0 0.14 11.7 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain Mg_chelatase PF01078.16 EPS27980.1 - 0.037 13.1 0.1 0.064 12.4 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_21 PF13304.1 EPS27980.1 - 0.065 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EPS27980.1 - 0.12 12.7 2.6 1.3 9.2 1.8 2.1 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EPS27980.1 - 0.15 12.2 0.0 0.44 10.7 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ALIX_LYPXL_bnd PF13949.1 EPS27980.1 - 0.17 10.8 0.3 0.27 10.1 0.2 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV NIF PF03031.13 EPS27981.1 - 4e-52 176.0 0.3 5.6e-52 175.6 0.2 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase LRR_4 PF12799.2 EPS27982.1 - 2.7e-46 154.5 32.6 9.7e-11 41.0 2.0 7.3 4 2 4 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPS27982.1 - 3.6e-23 81.0 56.0 4.4e-08 32.7 2.3 5.5 2 1 5 7 7 7 7 Leucine rich repeat LRR_1 PF00560.28 EPS27982.1 - 2.7e-17 60.1 31.9 0.23 11.6 0.0 11.5 10 1 1 11 11 11 7 Leucine Rich Repeat LRR_6 PF13516.1 EPS27982.1 - 1.7e-15 55.3 26.8 0.05 13.6 0.1 11.0 7 2 5 12 12 12 5 Leucine Rich repeat LRR_9 PF14580.1 EPS27982.1 - 2.9e-12 46.5 16.6 9.1e-06 25.3 1.3 4.2 1 1 3 4 4 4 4 Leucine-rich repeat LRR_7 PF13504.1 EPS27982.1 - 5.6e-12 43.7 22.7 0.35 11.2 0.0 10.6 10 1 1 11 11 11 3 Leucine rich repeat S-layer PF07752.6 EPS27982.1 - 0.22 10.6 1.9 0.9 8.6 0.1 2.1 2 0 0 2 2 2 0 S-layer protein Aldo_ket_red PF00248.16 EPS27984.1 - 2.4e-52 177.5 0.0 2.8e-52 177.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF223 PF02721.9 EPS27986.1 - 0.31 11.1 1.3 5.5 7.1 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF223 TEA PF01285.13 EPS27987.1 - 1.4e-135 452.8 0.1 2.1e-135 452.2 0.1 1.3 1 0 0 1 1 1 1 TEA/ATTS domain family Myb_DNA-binding PF00249.26 EPS27987.1 - 0.092 12.8 0.2 0.43 10.6 0.1 2.2 2 1 0 2 2 2 0 Myb-like DNA-binding domain RRM_1 PF00076.17 EPS27989.1 - 1.4e-72 239.2 0.4 1e-17 63.4 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS27989.1 - 2.2e-59 197.3 0.2 4.9e-13 48.8 0.0 5.6 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS27989.1 - 5.3e-32 109.4 0.0 4.9e-08 32.6 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPS27989.1 - 1.2e-05 24.9 0.0 2.7 7.8 0.0 3.7 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 EPS27989.1 - 0.00018 21.2 0.8 1.8 8.3 0.0 4.8 5 0 0 5 5 5 1 Limkain b1 RNA_bind PF08675.6 EPS27989.1 - 0.01 15.7 0.0 1.6 8.7 0.0 4.0 4 1 1 5 5 5 0 RNA binding domain Dynein_light PF01221.13 EPS27990.1 - 8.7e-41 137.8 3.6 1e-40 137.5 2.5 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Peptidase_C3 PF00548.15 EPS27990.1 - 0.019 14.7 0.2 0.021 14.6 0.1 1.1 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) RFC1 PF08519.7 EPS27990.1 - 0.062 13.0 0.2 0.078 12.7 0.2 1.2 1 0 0 1 1 1 0 Replication factor RFC1 C terminal domain DUF2766 PF10964.3 EPS27990.1 - 0.081 12.8 0.3 0.11 12.3 0.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2766) SSF PF00474.12 EPS27992.1 - 3.1e-18 65.6 32.1 5.9e-18 64.6 22.3 1.5 1 0 0 1 1 1 1 Sodium:solute symporter family WTF PF03303.8 EPS27992.1 - 0.066 12.6 0.0 0.066 12.6 0.0 2.3 2 0 0 2 2 2 0 WTF protein Sec61_beta PF03911.11 EPS27993.1 - 3e-18 65.3 0.3 4.7e-18 64.6 0.2 1.3 1 0 0 1 1 1 1 Sec61beta family DUF2730 PF10805.3 EPS27994.1 - 0.014 15.1 0.2 0.89 9.3 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) SCIMP PF15050.1 EPS27994.1 - 0.018 14.9 2.7 0.55 10.1 0.0 3.4 4 0 0 4 4 4 0 SCIMP protein Hid1 PF12722.2 EPS27994.1 - 0.15 9.7 0.3 0.18 9.4 0.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FMN_dh PF01070.13 EPS27995.1 - 8.9e-105 350.4 0.0 1e-104 350.2 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EPS27995.1 - 0.0007 18.5 1.2 0.001 18.0 0.8 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EPS27995.1 - 0.0023 16.9 0.2 0.0033 16.3 0.2 1.1 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 EPS27995.1 - 0.0074 15.5 0.2 0.018 14.3 0.1 1.5 1 0 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.9 EPS27995.1 - 0.035 13.1 0.9 0.18 10.8 0.4 2.3 2 1 0 2 2 2 0 Thiazole biosynthesis protein ThiG PCNA_C PF02747.10 EPS27998.1 - 1.6e-52 176.7 0.0 4.2e-52 175.4 0.0 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.13 EPS27998.1 - 1.9e-32 111.4 0.5 3.7e-32 110.4 0.3 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad9 PF04139.8 EPS27998.1 - 0.00021 20.5 0.0 0.00026 20.1 0.0 1.1 1 0 0 1 1 1 1 Rad9 Vezatin PF12632.2 EPS27999.1 - 8.8e-59 198.6 0.0 2.1e-58 197.4 0.0 1.7 2 0 0 2 2 2 1 Mysoin-binding motif of peroxisomes IQ PF00612.22 EPS28000.1 - 0.0041 16.6 0.5 0.01 15.4 0.3 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif 2OG-FeII_Oxy PF03171.15 EPS28001.1 - 1.4e-13 50.9 0.0 2.5e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EPS28001.1 - 2.7e-11 44.0 0.0 8.2e-11 42.4 0.0 1.8 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal DUF3336 PF11815.3 EPS28002.1 - 2.8e-48 163.1 5.7 4.4e-48 162.4 3.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EPS28002.1 - 9.5e-20 71.4 0.4 8.4e-19 68.2 0.0 2.7 3 1 1 4 4 4 1 Patatin-like phospholipase LRR_4 PF12799.2 EPS28003.1 - 2.6e-15 55.6 9.7 1.3e-05 24.7 2.2 5.4 3 2 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPS28003.1 - 2.5e-13 49.5 8.4 3.3e-08 33.1 1.8 3.7 2 1 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 EPS28003.1 - 3.4e-08 32.4 11.3 0.55 10.4 0.7 6.7 5 1 0 5 5 5 4 Leucine Rich Repeat LRR_7 PF13504.1 EPS28003.1 - 0.0096 15.9 14.0 27 5.5 0.1 6.1 5 0 0 5 5 5 1 Leucine rich repeat LRR_6 PF13516.1 EPS28003.1 - 0.12 12.5 10.5 45 4.5 0.0 5.5 4 1 1 5 5 5 0 Leucine Rich repeat Metallophos PF00149.23 EPS28004.1 - 1.4e-44 151.8 0.2 1.7e-44 151.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Arf PF00025.16 EPS28006.1 - 2e-64 216.0 0.0 2.2e-64 215.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EPS28006.1 - 1.5e-10 40.3 0.2 5.6e-07 28.5 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EPS28006.1 - 3.2e-08 33.0 0.0 4.2e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EPS28006.1 - 4.8e-07 30.2 0.0 6.3e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EPS28006.1 - 7.3e-07 29.1 0.0 9.6e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 EPS28006.1 - 2.6e-05 23.6 0.0 3.5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EPS28006.1 - 0.0001 21.5 0.0 0.00011 21.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EPS28006.1 - 0.016 14.6 0.0 0.57 9.5 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain cobW PF02492.14 EPS28006.1 - 0.031 13.7 0.0 3.7 6.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 EPS28006.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF2457 PF10446.4 EPS28007.1 - 1.8e-170 567.6 26.2 1.8e-170 567.6 18.2 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF2457) Nop14 PF04147.7 EPS28007.1 - 0.55 8.0 26.2 0.032 12.1 14.5 1.5 2 0 0 2 2 2 0 Nop14-like family CDC45 PF02724.9 EPS28007.1 - 6.2 4.7 14.7 11 3.8 10.2 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF2282 PF10048.4 EPS28008.1 - 0.074 12.9 0.1 0.079 12.8 0.1 1.2 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2282) TPR_11 PF13414.1 EPS28009.1 - 5.8e-23 80.3 18.7 2.2e-05 24.0 0.0 8.2 7 2 3 10 10 10 4 TPR repeat TPR_19 PF14559.1 EPS28009.1 - 5.4e-16 58.6 7.4 0.0025 18.0 0.0 7.1 6 1 2 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.12 EPS28009.1 - 4.5e-13 48.0 15.2 0.0029 17.3 0.0 8.7 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_17 PF13431.1 EPS28009.1 - 1.1e-12 47.0 0.4 0.085 13.0 0.0 7.1 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 EPS28009.1 - 1.5e-12 46.3 1.8 0.01 15.5 0.1 7.7 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 EPS28009.1 - 4.6e-12 45.4 17.0 0.38 11.5 0.2 9.4 6 3 4 10 10 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 EPS28009.1 - 5.5e-11 42.8 17.4 6.5e-05 23.4 0.0 6.6 6 1 2 8 8 7 3 Tetratricopeptide repeat TPR_1 PF00515.23 EPS28009.1 - 1.1e-10 40.6 11.2 0.084 12.5 0.0 8.7 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.1 EPS28009.1 - 5.3e-09 35.8 17.7 0.0045 16.8 0.1 6.9 6 2 3 9 9 8 4 Tetratricopeptide repeat Apc3 PF12895.2 EPS28009.1 - 9.2e-09 35.3 11.7 0.028 14.5 0.5 7.2 6 1 1 7 7 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EPS28009.1 - 8.9e-07 28.2 5.6 0.28 11.1 0.0 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat NARP1 PF12569.3 EPS28009.1 - 0.0024 16.7 0.3 0.59 8.8 0.0 2.9 3 0 0 3 3 3 1 NMDA receptor-regulated protein 1 TPR_9 PF13371.1 EPS28009.1 - 0.035 13.9 3.6 0.27 11.1 0.1 4.0 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EPS28009.1 - 0.092 13.2 6.7 22 5.7 0.0 6.3 9 0 0 9 9 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 EPS28009.1 - 3 8.5 9.4 16 6.3 0.1 5.7 7 0 0 7 7 6 0 Tetratricopeptide repeat SAM_2 PF07647.12 EPS28010.1 - 2e-09 37.1 0.1 5.1e-09 35.8 0.0 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EPS28010.1 - 2.6e-05 24.2 0.4 5.9e-05 23.1 0.1 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Rab5ip PF07019.7 EPS28011.1 - 1.4e-08 34.7 1.5 1.4e-08 34.7 1.0 2.1 2 0 0 2 2 2 1 Rab5-interacting protein (Rab5ip) Sulfate_transp PF00916.15 EPS28012.1 - 4.2e-76 255.6 10.1 7.7e-76 254.7 7.0 1.5 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EPS28012.1 - 1.5e-30 104.7 4.0 1.5e-30 104.7 2.7 3.2 5 0 0 5 5 5 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EPS28012.1 - 4e-09 35.8 0.0 8e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 STAS domain SNN_transmemb PF09049.5 EPS28012.1 - 1.9 8.2 10.5 0.031 13.9 1.2 2.7 2 0 0 2 2 2 0 Stannin transmembrane CC PF04942.9 EPS28013.1 - 0.0018 18.0 1.3 0.0041 16.9 0.9 1.6 1 0 0 1 1 1 1 CC domain Acetyltransf_1 PF00583.19 EPS28014.1 - 1e-11 44.6 0.0 1.4e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EPS28014.1 - 2.3e-06 27.2 0.0 4e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EPS28014.1 - 0.0012 18.9 0.0 0.0022 18.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPS28014.1 - 0.024 14.7 0.0 0.034 14.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPS28014.1 - 0.1 12.4 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MFS_1 PF07690.11 EPS28015.1 - 1.7e-20 73.0 56.1 4.3e-14 51.9 25.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RNA_pol_Rpb6 PF01192.17 EPS28016.1 - 6e-24 83.5 0.1 1e-23 82.8 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 KOW PF00467.24 EPS28016.1 - 0.011 15.4 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 0 KOW motif zf-C2H2 PF00096.21 EPS28017.1 - 5.1e-29 98.8 61.0 5.5e-05 23.2 0.4 11.3 11 1 0 11 11 11 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPS28017.1 - 1.1e-23 81.7 57.8 0.0027 17.9 0.5 10.9 10 1 0 10 10 10 8 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EPS28017.1 - 3.7e-19 67.9 60.9 0.00021 21.4 0.6 11.0 11 0 0 11 11 11 8 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EPS28017.1 - 2.7e-06 27.3 16.9 5.4 7.2 0.0 8.5 9 0 0 9 9 9 3 Zinc-finger double-stranded RNA-binding GAGA PF09237.6 EPS28017.1 - 0.0037 16.8 2.0 0.0037 16.8 1.4 2.9 3 0 0 3 3 3 1 GAGA factor zf-H2C2_5 PF13909.1 EPS28017.1 - 0.046 13.9 0.5 0.046 13.9 0.4 10.0 11 2 0 11 11 11 0 C2H2-type zinc-finger domain zf-met PF12874.2 EPS28017.1 - 0.16 12.2 13.8 18 5.7 0.2 6.9 8 0 0 8 8 8 0 Zinc-finger of C2H2 type CHORD PF04968.7 EPS28017.1 - 2.8 8.2 25.9 1.5 9.1 1.3 5.6 4 3 2 6 6 6 0 CHORD ECH PF00378.15 EPS28019.1 - 6e-44 150.0 0.0 7e-44 149.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EPS28019.1 - 0.00069 19.4 0.0 0.0045 16.7 0.0 2.1 2 0 0 2 2 2 1 Peptidase family S49 PH PF00169.24 EPS28021.1 - 0.00013 22.0 0.0 0.0012 19.0 0.0 2.7 2 1 0 2 2 2 1 PH domain COPIIcoated_ERV PF07970.7 EPS28022.1 - 2e-68 230.3 0.0 2.4e-44 151.5 0.0 2.5 3 0 0 3 3 3 2 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EPS28022.1 - 4.3e-35 119.5 0.0 1.8e-34 117.5 0.0 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) TAP_C PF03943.8 EPS28023.1 - 2.1e-13 49.4 0.2 4.3e-13 48.4 0.2 1.5 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.2 EPS28023.1 - 5.8e-09 35.3 11.0 8.7e-06 25.2 2.0 2.6 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPS28023.1 - 2.2e-05 24.0 0.8 4.1e-05 23.2 0.6 1.5 1 0 0 1 1 1 1 Leucine rich repeat NTF2 PF02136.15 EPS28023.1 - 4e-05 23.9 0.0 0.00011 22.5 0.0 1.8 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_1 PF00560.28 EPS28023.1 - 0.0091 15.8 3.8 1.9 8.8 0.4 3.7 2 1 1 3 3 3 1 Leucine Rich Repeat LRR_6 PF13516.1 EPS28023.1 - 0.0092 15.9 0.5 1.5 9.1 0.1 3.2 3 0 0 3 3 3 1 Leucine Rich repeat LRR_7 PF13504.1 EPS28023.1 - 0.037 14.2 2.2 2.1 8.8 0.1 3.5 3 0 0 3 3 3 0 Leucine rich repeat Alpha_E3_glycop PF01563.11 EPS28024.1 - 0.15 11.8 0.0 0.21 11.4 0.0 1.1 1 0 0 1 1 1 0 Alphavirus E3 glycoprotein Vps53_N PF04100.7 EPS28025.1 - 1.7e-106 356.2 5.2 1.7e-106 356.2 3.6 1.7 2 0 0 2 2 2 1 Vps53-like, N-terminal DUF2450 PF10475.4 EPS28025.1 - 1.5e-07 30.5 8.6 3.5e-07 29.4 6.0 1.5 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) COG2 PF06148.6 EPS28025.1 - 4e-05 23.4 4.0 4e-05 23.4 2.8 2.2 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Spc7 PF08317.6 EPS28025.1 - 0.0008 18.1 6.4 0.0016 17.1 4.5 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein Zw10 PF06248.8 EPS28025.1 - 0.014 13.6 9.7 0.0088 14.2 4.8 2.0 2 0 0 2 2 2 0 Centromere/kinetochore Zw10 Sigma70_ner PF04546.8 EPS28025.1 - 0.029 13.9 4.3 0.068 12.7 2.9 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region HsbA PF12296.3 EPS28025.1 - 0.15 11.8 6.3 0.57 10.0 4.4 1.9 1 0 0 1 1 1 0 Hydrophobic surface binding protein A DUF1515 PF07439.6 EPS28025.1 - 0.36 10.6 5.5 0.51 10.1 1.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Baculo_PEP_C PF04513.7 EPS28025.1 - 0.49 10.2 8.1 0.57 10.0 3.7 2.5 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 EPS28025.1 - 2.3 7.7 12.8 0.28 10.7 4.6 2.4 2 0 0 2 2 2 0 IncA protein Ribosomal_L10 PF00466.15 EPS28026.1 - 1.6e-25 88.9 0.2 3.2e-25 87.9 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 EPS28026.1 - 4.2e-18 65.5 6.6 7e-18 64.8 2.5 2.3 2 0 0 2 2 2 1 60s Acidic ribosomal protein WD40 PF00400.27 EPS28027.1 - 3.3e-05 23.5 1.6 0.0036 17.1 0.1 3.9 3 0 0 3 3 3 1 WD domain, G-beta repeat URO-D PF01208.12 EPS28028.1 - 1.2e-123 412.3 0.0 1.4e-123 412.2 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) dCMP_cyt_deam_1 PF00383.17 EPS28029.1 - 5.8e-24 83.6 0.0 7.4e-24 83.3 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EPS28029.1 - 3.3e-05 23.7 0.7 0.12 12.2 0.7 2.2 1 1 1 2 2 2 2 Bd3614-like deaminase XOO_2897-deam PF14440.1 EPS28029.1 - 0.015 14.9 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase APOBEC_N PF08210.6 EPS28029.1 - 0.021 14.4 0.1 0.029 14.0 0.1 1.4 1 1 0 1 1 1 0 APOBEC-like N-terminal domain DnaJ PF00226.26 EPS28030.1 - 4.5e-25 87.1 2.0 9.1e-25 86.1 1.4 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EPS28030.1 - 3.4e-21 74.9 0.4 3e-18 65.5 0.0 2.7 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EPS28030.1 - 6.2e-14 51.7 19.6 1.1e-13 50.9 13.6 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EPS28030.1 - 0.062 12.9 10.5 0.07 12.8 1.7 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF2614 PF11023.3 EPS28030.1 - 2.4 7.9 5.0 2.5 7.9 0.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) PADR1 PF08063.7 EPS28030.1 - 8.7 5.8 8.7 24 4.4 0.3 3.5 2 1 1 3 3 3 0 PADR1 (NUC008) domain CENP-Q PF13094.1 EPS28031.1 - 9.2 6.2 8.5 15 5.5 4.1 2.5 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit PCI PF01399.22 EPS28032.1 - 1.1e-09 38.5 4.7 1.5e-09 38.0 0.0 3.3 3 0 0 3 3 3 1 PCI domain G-gamma PF00631.17 EPS28033.1 - 1.9e-25 88.3 0.0 2.2e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 GGL domain RSS_P20 PF11757.3 EPS28033.1 - 0.035 14.2 0.0 0.041 14.0 0.0 1.1 1 0 0 1 1 1 0 Suppressor of RNA silencing P21-like DUF3220 PF11516.3 EPS28033.1 - 0.044 13.7 0.0 0.059 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3120) PUB PF09409.5 EPS28033.1 - 0.11 12.2 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 PUB domain Rdx PF10262.4 EPS28034.1 - 1.1e-28 99.0 0.0 1.6e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Rdx family CHZ PF09649.5 EPS28035.1 - 0.00048 19.3 0.2 0.0014 17.7 0.1 1.8 1 0 0 1 1 1 1 Histone chaperone domain CHZ Sec3_C_2 PF15278.1 EPS28035.1 - 0.057 13.5 0.4 0.07 13.2 0.3 1.2 1 0 0 1 1 1 0 Sec3 exocyst complex subunit Heme_oxygenase PF01126.15 EPS28036.1 - 0.00016 21.3 0.0 0.11 11.9 0.0 2.8 3 0 0 3 3 3 2 Heme oxygenase PDEase_I PF00233.14 EPS28038.1 - 2.1e-48 165.1 0.0 3.7e-47 161.0 0.0 2.1 1 1 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DUF2376 PF09550.5 EPS28038.1 - 0.036 14.2 0.1 0.29 11.2 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical phage protein (DUF2376) Exo70 PF03081.10 EPS28038.1 - 0.043 12.6 0.0 0.069 11.9 0.0 1.2 1 0 0 1 1 1 0 Exo70 exocyst complex subunit ADH_zinc_N PF00107.21 EPS28039.1 - 1.8e-25 88.9 0.0 3e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPS28039.1 - 6e-14 53.0 0.0 1.2e-13 52.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPS28039.1 - 3.5e-11 42.8 0.0 3.3e-09 36.4 0.0 2.5 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain zf-HC5HC2H_2 PF13832.1 EPS28040.1 - 9.9e-21 73.8 1.1 9.9e-21 73.8 0.8 4.1 4 0 0 4 4 4 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EPS28040.1 - 1.5e-19 69.9 2.3 1.5e-19 69.9 1.6 4.0 4 0 0 4 4 4 1 PHD-like zinc-binding domain BAH PF01426.13 EPS28040.1 - 2e-16 59.7 0.0 3.7e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 BAH domain PHD PF00628.24 EPS28040.1 - 1.3e-09 37.5 45.8 5.2e-07 29.2 3.9 5.3 6 0 0 6 6 6 3 PHD-finger PHD_2 PF13831.1 EPS28040.1 - 1.9e-09 36.6 2.6 1.9e-09 36.6 1.8 5.0 6 0 0 6 6 6 1 PHD-finger Myb_DNA-binding PF00249.26 EPS28040.1 - 0.00013 21.9 0.1 0.0024 17.9 0.0 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain zf-RING-like PF08746.6 EPS28040.1 - 8.4 6.4 38.5 0.25 11.3 1.0 4.1 4 0 0 4 4 4 0 RING-like domain DEAD PF00270.24 EPS28041.1 - 4.7e-18 65.2 0.1 2.4e-17 62.9 0.0 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPS28041.1 - 5.5e-09 35.7 0.1 1.3e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPS28041.1 - 1.3e-06 28.4 0.0 2.7e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HHH_5 PF14520.1 EPS28041.1 - 0.00021 21.3 0.0 0.0031 17.6 0.0 2.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain AAA_22 PF13401.1 EPS28041.1 - 0.01 15.9 0.5 0.13 12.3 0.1 2.9 2 1 0 2 2 2 0 AAA domain DUF4332 PF14229.1 EPS28041.1 - 0.048 13.6 0.0 0.16 11.9 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4332) PI-PLC-X PF00388.14 EPS28042.1 - 0.023 14.1 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Ank PF00023.25 EPS28042.1 - 0.037 13.8 0.2 3.6 7.5 0.0 3.2 2 1 0 2 2 2 0 Ankyrin repeat Vps8 PF12816.2 EPS28043.1 - 3.8e-70 235.1 0.0 9.1e-70 233.9 0.0 1.7 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 EPS28043.1 - 2.3e-05 24.0 0.0 0.12 11.9 0.0 3.2 2 0 0 2 2 2 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 EPS28043.1 - 0.0023 17.7 1.3 0.0023 17.7 0.9 2.2 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 EPS28043.1 - 0.0061 16.5 0.6 0.019 14.9 0.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Pox_D3 PF04580.8 EPS28043.1 - 0.028 13.6 0.0 0.049 12.8 0.0 1.3 1 0 0 1 1 1 0 Chordopoxvirinae D3 protein zf-RING_6 PF14835.1 EPS28043.1 - 0.099 12.4 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 EPS28043.1 - 0.32 11.1 2.1 2.1 8.5 0.5 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger zf-RING_5 PF14634.1 EPS28043.1 - 1.1 9.0 3.5 0.43 10.3 0.3 1.9 2 0 0 2 2 2 0 zinc-RING finger domain Glyco_hydro_16 PF00722.16 EPS28044.1 - 6.1e-11 41.9 0.6 2.2e-10 40.1 0.0 2.2 1 1 2 3 3 3 1 Glycosyl hydrolases family 16 Glyco_transf_90 PF05686.7 EPS28045.1 - 4e-12 45.5 0.1 0.00011 21.0 0.0 3.4 3 1 0 3 3 3 3 Glycosyl transferase family 90 GNAT_acetyltr_2 PF13718.1 EPS28046.1 - 6e-79 263.9 0.0 1e-78 263.1 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 EPS28046.1 - 6.8e-67 224.5 0.0 3e-66 222.4 0.0 2.0 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 EPS28046.1 - 5.1e-40 135.0 0.0 1.2e-39 133.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 EPS28046.1 - 8.7e-38 128.5 0.7 2.6e-37 126.9 0.5 1.8 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 EPS28046.1 - 0.0048 17.0 0.0 0.014 15.4 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AAA_19 PF13245.1 EPS28046.1 - 0.018 14.8 0.3 0.2 11.4 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain Acetyltransf_1 PF00583.19 EPS28046.1 - 0.036 14.1 0.2 0.27 11.2 0.0 2.5 3 0 0 3 3 3 0 Acetyltransferase (GNAT) family Thioredoxin PF00085.15 EPS28047.1 - 3.1e-33 113.5 0.3 2.7e-26 91.2 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 EPS28047.1 - 7.1e-09 35.8 1.1 0.00044 20.4 0.2 2.8 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EPS28047.1 - 1.2e-07 31.7 0.1 0.00041 20.4 0.0 3.8 3 2 1 4 4 4 2 Thioredoxin-like Thioredoxin_6 PF13848.1 EPS28047.1 - 6e-07 29.4 0.0 2.3e-06 27.5 0.0 1.9 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 EPS28047.1 - 0.0051 16.6 0.3 0.38 10.6 0.1 2.5 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_7 PF13899.1 EPS28047.1 - 0.006 16.5 0.0 0.016 15.1 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 EPS28047.1 - 0.012 15.3 0.0 0.031 13.9 0.0 1.7 1 0 0 1 1 1 0 AhpC/TSA family HyaE PF07449.6 EPS28047.1 - 0.065 13.1 0.1 0.44 10.4 0.1 2.3 1 1 0 1 1 1 0 Hydrogenase-1 expression protein HyaE ATP-synt PF00231.14 EPS28048.1 - 2e-68 230.8 8.9 2.4e-68 230.6 6.2 1.0 1 0 0 1 1 1 1 ATP synthase Beta-Casp PF10996.3 EPS28048.1 - 0.045 13.6 0.0 0.085 12.7 0.0 1.6 1 0 0 1 1 1 0 Beta-Casp domain Topoisom_I_N PF02919.10 EPS28049.1 - 2.5e-97 324.3 2.9 2.5e-97 324.3 2.0 3.7 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 EPS28049.1 - 9.5e-83 276.8 6.1 9.5e-83 276.8 4.2 2.3 2 1 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 EPS28049.1 - 8.2e-32 108.6 0.3 3.1e-31 106.8 0.2 2.1 1 0 0 1 1 1 1 C-terminal topoisomerase domain Ribosomal_S15 PF00312.17 EPS28049.1 - 1.3 8.8 7.3 0.18 11.5 0.8 2.6 2 0 0 2 2 2 0 Ribosomal protein S15 Epimerase PF01370.16 EPS28050.1 - 2.2e-20 73.0 0.0 3.5e-20 72.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPS28050.1 - 3.5e-08 32.5 0.0 1.6e-07 30.3 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EPS28050.1 - 3.3e-07 30.3 0.0 1.2e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EPS28050.1 - 2.3e-06 26.7 0.0 4.1e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EPS28050.1 - 0.0002 21.4 0.1 0.0015 18.5 0.0 2.3 2 1 0 2 2 2 1 NADH(P)-binding KR PF08659.5 EPS28050.1 - 0.0019 17.9 0.1 0.0091 15.6 0.0 2.0 2 0 0 2 2 2 1 KR domain Ldh_1_N PF00056.18 EPS28050.1 - 0.03 14.1 0.0 0.064 13.0 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EPS28050.1 - 0.071 12.0 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase DUF605 PF04652.11 EPS28052.1 - 2.5e-100 336.5 8.1 2.9e-100 336.3 5.6 1.0 1 0 0 1 1 1 1 Vta1 like Peptidase_C2 PF00648.16 EPS28053.1 - 1.1e-18 67.3 0.0 3.3e-18 65.7 0.0 1.7 1 1 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 EPS28053.1 - 2.1e-18 66.3 0.0 2e-14 53.4 0.0 3.0 3 1 0 3 3 3 2 Calpain large subunit, domain III MIT PF04212.13 EPS28053.1 - 0.0037 17.0 1.9 0.0065 16.3 1.3 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Mito_carr PF00153.22 EPS28054.1 - 1.4e-56 188.1 1.7 1.3e-20 72.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein SNase PF00565.12 EPS28055.1 - 4e-21 75.3 0.1 5.7e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue ADK PF00406.17 EPS28056.1 - 4.4e-35 120.7 0.0 6.9e-20 71.4 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.9 EPS28056.1 - 4.5e-13 48.6 0.0 7.8e-13 47.8 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.1 EPS28056.1 - 0.00051 20.3 0.0 0.0073 16.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EPS28056.1 - 0.00063 20.5 0.0 0.0024 18.7 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EPS28056.1 - 0.00071 19.4 0.0 0.031 14.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EPS28056.1 - 0.032 13.3 0.1 0.091 11.8 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_5 PF07728.9 EPS28056.1 - 0.11 12.1 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 EPS28056.1 - 0.14 12.0 0.2 0.4 10.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain DNA_primase_lrg PF04104.9 EPS28057.1 - 2.3e-84 282.7 0.0 3.1e-84 282.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Sec23_trunk PF04811.10 EPS28058.1 - 1.3e-79 267.0 0.0 1.8e-79 266.5 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EPS28058.1 - 2.3e-33 113.7 0.0 5.2e-33 112.5 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EPS28058.1 - 2.1e-29 101.8 0.0 4.3e-29 100.8 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EPS28058.1 - 2.9e-16 58.7 3.8 6.2e-16 57.6 2.7 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EPS28058.1 - 7.3e-12 44.8 0.0 1.6e-11 43.6 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Ribosomal_L11_N PF03946.9 EPS28059.1 - 1.5e-17 62.7 0.0 2.3e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EPS28059.1 - 3.3e-10 39.9 0.2 5.1e-10 39.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Glyco_transf_41 PF13844.1 EPS28061.1 - 2.1e-99 332.6 0.0 2.3e-51 174.2 0.0 3.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_11 PF13414.1 EPS28061.1 - 3.2e-20 71.5 14.8 6.3e-07 28.9 0.1 4.8 4 0 0 4 4 4 3 TPR repeat TPR_1 PF00515.23 EPS28061.1 - 6.6e-17 60.3 10.9 1.5e-05 24.3 0.1 6.1 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 EPS28061.1 - 4.1e-14 51.2 13.6 0.0024 17.6 0.0 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 EPS28061.1 - 1.3e-12 47.4 10.0 1.6e-07 31.1 0.8 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EPS28061.1 - 2.8e-11 42.6 8.7 0.029 14.5 0.2 5.6 5 0 0 5 5 4 4 Tetratricopeptide repeat TPR_14 PF13428.1 EPS28061.1 - 2.1e-10 40.2 11.5 0.0011 19.4 0.1 5.9 4 2 2 6 6 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 EPS28061.1 - 2.1e-10 40.9 17.1 0.00041 20.9 0.3 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EPS28061.1 - 2.6e-08 33.0 7.7 0.0024 17.5 0.0 5.2 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EPS28061.1 - 4e-08 33.4 5.4 0.001 19.3 0.8 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EPS28061.1 - 1.7e-06 27.4 5.6 0.18 11.6 0.1 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 EPS28061.1 - 3.2e-05 23.6 18.8 0.04 13.8 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_5 PF12688.2 EPS28061.1 - 0.0012 18.9 0.9 0.038 14.0 0.1 3.1 3 0 0 3 3 3 1 Tetratrico peptide repeat Apc3 PF12895.2 EPS28061.1 - 0.0012 18.8 3.0 0.19 11.8 0.0 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 EPS28061.1 - 0.0018 17.3 2.7 0.037 13.0 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.12 EPS28061.1 - 0.039 14.2 3.3 3.4 7.9 0.0 3.2 3 0 0 3 3 3 0 Bacterial transcriptional activator domain TPR_9 PF13371.1 EPS28061.1 - 0.046 13.5 6.4 0.17 11.7 0.1 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF2225 PF09986.4 EPS28061.1 - 0.21 11.0 0.0 1.1 8.6 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_6 PF13174.1 EPS28061.1 - 0.38 11.2 9.4 33 5.2 0.0 4.7 5 0 0 5 5 3 0 Tetratricopeptide repeat DUF2353 PF09789.4 EPS28061.1 - 0.99 8.5 0.0 1.6 7.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Myb_DNA-binding PF00249.26 EPS28062.1 - 1.1e-24 86.2 1.8 2.4e-13 49.9 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EPS28062.1 - 6.8e-21 74.1 3.0 6.6e-15 54.9 0.1 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain DUF2774 PF11242.3 EPS28062.1 - 0.012 15.5 0.0 0.038 13.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) Myb_DNA-bind_4 PF13837.1 EPS28062.1 - 0.013 15.5 1.1 0.048 13.7 0.1 2.3 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain HTH_23 PF13384.1 EPS28062.1 - 0.031 13.9 0.1 0.079 12.6 0.0 1.6 2 0 0 2 2 2 0 Homeodomain-like domain HTH_38 PF13936.1 EPS28062.1 - 0.033 13.7 0.1 0.062 12.8 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Glyco_hydro_31 PF01055.21 EPS28064.1 - 5.5e-123 411.0 3.4 7.2e-123 410.6 2.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EPS28064.1 - 6.6e-05 22.6 0.7 0.0015 18.3 0.1 3.1 3 1 0 3 3 3 1 Galactose mutarotase-like DUF2414 PF10309.4 EPS28065.1 - 6.8e-25 86.5 0.1 1e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) RNA_bind PF08675.6 EPS28065.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 RNA binding domain WD40 PF00400.27 EPS28066.1 - 0.39 10.6 9.3 7.7 6.5 0.0 4.5 5 0 0 5 5 5 0 WD domain, G-beta repeat Ribosomal_L29e PF01779.12 EPS28067.1 - 1.1e-21 76.3 8.9 1.1e-21 76.3 6.2 1.5 2 0 0 2 2 2 1 Ribosomal L29e protein family ATP-synt_DE_N PF02823.11 EPS28068.1 - 1.7e-20 72.5 0.1 2.3e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Cytochrom_B561 PF03188.11 EPS28071.1 - 0.038 13.8 11.9 0.06 13.1 7.2 2.0 1 1 0 1 1 1 0 Eukaryotic cytochrome b561 DUF533 PF04391.7 EPS28071.1 - 0.54 9.5 5.1 0.53 9.6 1.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF533) CopD PF05425.8 EPS28071.1 - 7 6.9 10.7 12 6.2 3.6 3.8 2 1 2 4 4 4 0 Copper resistance protein D PQ-loop PF04193.9 EPS28072.1 - 2.8e-26 90.8 21.2 6.9e-17 60.7 1.2 3.5 3 0 0 3 3 3 2 PQ loop repeat zf-C2H2_4 PF13894.1 EPS28074.1 - 0.00021 21.4 13.7 0.68 10.3 0.0 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EPS28074.1 - 0.075 13.4 0.1 0.075 13.4 0.1 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type APH PF01636.18 EPS28075.1 - 0.036 13.7 0.0 0.071 12.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1115 PF06544.7 EPS28076.1 - 0.11 12.1 0.4 0.12 12.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1115) zf-H2C2_2 PF13465.1 EPS28077.1 - 5.1e-06 26.5 7.5 0.11 12.8 0.1 4.3 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EPS28077.1 - 5.9e-06 26.2 15.9 0.00078 19.6 2.0 4.4 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EPS28077.1 - 1.2e-05 25.2 13.2 0.0063 16.7 1.2 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-Di19 PF05605.7 EPS28077.1 - 1 9.5 7.3 0.22 11.6 0.7 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding SR-25 PF10500.4 EPS28078.1 - 0.011 15.2 2.0 0.011 15.2 1.4 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein dUTPase PF00692.14 EPS28080.1 - 7.3e-42 141.8 0.0 9.3e-42 141.5 0.0 1.1 1 0 0 1 1 1 1 dUTPase DCD PF06559.6 EPS28080.1 - 0.032 12.6 0.0 0.046 12.1 0.0 1.2 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) Phos_pyr_kin PF08543.7 EPS28081.1 - 6.3e-11 41.9 0.0 1.4e-10 40.7 0.0 1.5 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 EPS28081.1 - 7.9e-07 28.4 2.2 6.5e-06 25.4 1.5 2.4 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Afi1 PF07792.7 EPS28083.1 - 1.1e-63 213.6 0.0 1.9e-63 212.8 0.0 1.4 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 EPS28083.1 - 1.9e-38 130.6 0.0 3.1e-38 129.9 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 EPS28083.1 - 4.8e-09 35.1 0.0 0.0027 16.2 0.0 3.8 3 1 1 4 4 4 3 Transport protein Avl9 DUF2347 PF09804.4 EPS28083.1 - 0.016 14.4 0.0 0.059 12.6 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) EF-hand_1 PF00036.27 EPS28084.1 - 7.4e-12 43.6 3.1 2.5e-05 23.2 0.2 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EPS28084.1 - 1.5e-11 43.1 4.8 5.5e-05 22.7 0.2 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 EPS28084.1 - 5e-09 36.1 5.8 1.3e-07 31.6 0.8 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EPS28084.1 - 1.1e-07 31.3 0.2 0.0097 15.5 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EPS28084.1 - 1.1e-06 27.6 6.5 0.0017 17.6 0.5 2.4 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.1 EPS28084.1 - 0.092 12.6 0.0 1.5 8.7 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain RabGAP-TBC PF00566.13 EPS28085.1 - 5.3e-29 101.2 0.0 2.2e-24 86.1 0.0 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain RRM_1 PF00076.17 EPS28086.1 - 1.6e-10 40.4 0.0 2.3e-07 30.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS28086.1 - 5.4e-08 32.7 0.0 1.3e-06 28.3 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS28086.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_3 PF14369.1 EPS28089.1 - 0.0065 16.4 3.5 0.037 14.0 0.3 2.3 2 1 1 3 3 3 1 zinc-finger C1_1 PF00130.17 EPS28089.1 - 0.061 13.0 0.3 0.1 12.3 0.2 1.4 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-CHY PF05495.7 EPS28089.1 - 0.064 13.4 0.4 0.078 13.1 0.3 1.1 1 0 0 1 1 1 0 CHY zinc finger DUF3268 PF11672.3 EPS28089.1 - 0.078 13.0 0.5 0.092 12.8 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3268) Zn_ribbon_recom PF13408.1 EPS28089.1 - 0.1 12.8 1.3 0.17 12.1 0.9 1.3 1 1 0 1 1 1 0 Recombinase zinc beta ribbon domain E7 PF00527.13 EPS28089.1 - 0.16 12.1 1.9 1 9.5 1.5 1.9 1 1 1 2 2 2 0 E7 protein, Early protein DNA_RNApol_7kD PF03604.8 EPS28089.1 - 0.19 11.2 1.7 11 5.6 0.0 2.2 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Yippee-Mis18 PF03226.9 EPS28089.1 - 0.37 10.8 3.3 4.7 7.3 0.3 2.0 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-FPG_IleRS PF06827.9 EPS28089.1 - 1.8 8.2 6.9 1.7 8.3 0.1 2.2 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Glucosamine_iso PF01182.15 EPS28090.1 - 3.2e-58 196.7 0.0 3.9e-58 196.4 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase WD40 PF00400.27 EPS28092.1 - 3.4e-23 80.6 13.4 5.5e-07 29.2 0.1 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat BSP_II PF05432.6 EPS28092.1 - 0.032 13.5 7.9 0.066 12.4 5.5 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CRT10 PF08728.5 EPS28092.1 - 0.22 9.4 0.0 10 3.9 0.0 2.2 2 0 0 2 2 2 0 CRT10 SET PF00856.23 EPS28093.1 - 7.1e-07 29.6 0.6 0.0016 18.7 0.0 3.0 4 0 0 4 4 4 2 SET domain TPR_9 PF13371.1 EPS28093.1 - 0.0083 15.9 0.4 0.021 14.6 0.3 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 EPS28093.1 - 0.17 11.5 3.3 0.22 11.1 1.2 1.9 2 0 0 2 2 2 0 TPR repeat Phage_XkdX PF09693.5 EPS28093.1 - 0.23 11.0 1.2 0.6 9.6 0.8 1.8 1 0 0 1 1 1 0 Phage uncharacterised protein (Phage_XkdX) zf-MYND PF01753.13 EPS28093.1 - 4.7 7.1 11.4 0.17 11.7 3.3 2.1 2 0 0 2 2 2 0 MYND finger MA3 PF02847.12 EPS28094.1 - 2.1e-26 91.8 0.0 7.1e-26 90.1 0.0 1.9 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.14 EPS28094.1 - 2.8e-26 92.2 1.7 3e-26 92.1 0.4 1.6 2 0 0 2 2 2 1 MIF4G domain NOA36 PF06524.7 EPS28094.1 - 3.5 6.7 10.7 6.5 5.9 7.4 1.4 1 0 0 1 1 1 0 NOA36 protein DPM2 PF07297.7 EPS28095.1 - 8.7e-34 115.6 1.0 1e-33 115.4 0.7 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DUF4083 PF13314.1 EPS28095.1 - 0.00031 20.5 0.1 0.00057 19.6 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4083) PIG-P PF08510.7 EPS28095.1 - 0.00032 20.3 0.8 0.00038 20.0 0.6 1.1 1 0 0 1 1 1 1 PIG-P Cytochrom_C_asm PF01578.15 EPS28095.1 - 0.061 12.8 0.2 0.065 12.7 0.2 1.0 1 0 0 1 1 1 0 Cytochrome C assembly protein DUF4229 PF14012.1 EPS28095.1 - 0.065 13.1 3.2 0.071 13.0 0.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4229) COX14 PF14880.1 EPS28095.1 - 0.069 12.7 2.4 0.15 11.7 0.0 2.0 2 0 0 2 2 2 0 Cytochrome oxidase c assembly HD PF01966.17 EPS28097.1 - 1e-06 28.7 0.1 6.9e-06 26.0 0.0 2.2 2 1 0 2 2 2 1 HD domain Spc7_N PF15402.1 EPS28098.1 - 0.11 10.4 12.0 0.13 10.2 8.3 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Golgin_A5 PF09787.4 EPS28098.1 - 6.7 5.1 6.7 8.6 4.7 4.7 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DEAD PF00270.24 EPS28099.1 - 4.2e-20 71.9 0.0 1.6e-19 70.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPS28099.1 - 3.1e-19 68.6 0.1 1e-18 66.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPS28099.1 - 5.8e-18 65.3 0.0 1.4e-17 64.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EPS28099.1 - 0.022 14.9 0.0 0.066 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EPS28099.1 - 0.06 12.3 0.0 0.12 11.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) F_actin_cap_B PF01115.12 EPS28100.1 - 4.5e-108 360.0 0.0 5.2e-108 359.8 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Med11 PF10280.4 EPS28101.1 - 4.9e-34 116.8 0.0 6.2e-34 116.5 0.0 1.1 1 0 0 1 1 1 1 Mediator complex protein Med29 PF11568.3 EPS28101.1 - 0.069 13.2 0.1 0.093 12.7 0.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 29 DUF4164 PF13747.1 EPS28101.1 - 0.12 12.5 0.2 0.34 11.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) WD40 PF00400.27 EPS28102.1 - 1.3e-54 180.2 15.3 8.6e-11 41.2 0.5 7.2 8 0 0 8 8 8 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EPS28102.1 - 1.6e-47 161.1 0.0 2.5e-47 160.5 0.0 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit Nup160 PF11715.3 EPS28102.1 - 6.2e-07 27.9 3.6 0.022 12.8 0.0 3.2 2 1 1 3 3 3 3 Nucleoporin Nup120/160 LisH PF08513.6 EPS28102.1 - 1.2e-06 28.0 0.0 2.4e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 LisH Nucleoporin_N PF08801.6 EPS28102.1 - 0.016 14.0 0.0 5.8 5.5 0.0 3.2 1 1 1 2 2 2 0 Nup133 N terminal like Nbas_N PF15492.1 EPS28102.1 - 0.019 14.0 0.5 1.3 8.0 0.1 2.7 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.6 EPS28102.1 - 0.028 14.1 0.6 0.12 12.1 0.0 2.3 3 0 0 3 3 3 0 Eukaryotic translation initiation factor eIF2A Abhydrolase_6 PF12697.2 EPS28103.1 - 1.1e-22 81.0 0.9 1.1e-22 81.0 0.6 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPS28103.1 - 1.5e-09 37.7 0.1 2.8e-09 36.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPS28103.1 - 4.6e-05 23.0 0.1 0.00069 19.2 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EPS28103.1 - 0.052 13.4 0.0 0.095 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Thioesterase PF00975.15 EPS28103.1 - 0.057 13.6 0.0 15 5.7 0.0 2.3 2 0 0 2 2 2 0 Thioesterase domain Lipase_3 PF01764.20 EPS28103.1 - 0.065 12.8 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Pkinase PF00069.20 EPS28104.1 - 1.1e-10 41.1 0.0 8.1e-10 38.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain DUF2417 PF10329.4 EPS28105.1 - 3.9e-82 275.1 1.2 5.1e-82 274.7 0.8 1.1 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 EPS28105.1 - 8.8e-09 35.5 0.4 1.6e-08 34.7 0.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3333 PF11812.3 EPS28105.1 - 0.2 11.6 1.3 0.45 10.4 0.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3333) NPL4 PF05021.10 EPS28106.1 - 2.6e-125 417.6 0.0 3.2e-125 417.3 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 EPS28106.1 - 2.9e-72 241.1 0.4 4.5e-72 240.5 0.3 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 EPS28106.1 - 0.0085 16.3 0.0 0.049 13.9 0.0 2.2 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 Flavodoxin_1 PF00258.20 EPS28107.1 - 2.1e-08 34.2 0.0 3e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.12 EPS28107.1 - 3.3e-07 30.0 0.0 4.2e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.10 EPS28107.1 - 1e-06 28.3 0.0 1.4e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_5 PF12724.2 EPS28107.1 - 0.066 13.2 0.0 0.31 11.0 0.0 1.8 1 1 1 2 2 2 0 Flavodoxin domain Bacteriocin_IIc PF10439.4 EPS28107.1 - 0.88 9.7 6.4 1.2 9.2 1.7 2.3 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide zf-CCCH PF00642.19 EPS28108.1 - 2.2e-16 59.0 28.7 2.4e-07 30.2 0.7 5.3 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.4 EPS28108.1 - 0.056 12.9 4.4 0.65 9.5 0.1 3.1 2 0 0 2 2 2 0 Putative zinc-finger domain Glyco_hydro_18 PF00704.23 EPS28109.1 - 2.2e-76 257.5 0.0 2.5e-76 257.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3142 PF11340.3 EPS28109.1 - 0.02 14.5 0.1 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3142) DUF218 PF02698.12 EPS28109.1 - 0.072 12.5 0.0 0.81 9.1 0.0 2.1 2 0 0 2 2 2 0 DUF218 domain Acyl-CoA_dh_1 PF00441.19 EPS28110.1 - 2e-16 60.4 0.0 4.9e-16 59.1 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EPS28110.1 - 7.9e-07 28.4 0.1 1.2e-05 24.7 0.1 2.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain AcylCoA_dehyd_C PF12186.3 EPS28110.1 - 0.052 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase C terminal DUF3632 PF12311.3 EPS28111.1 - 9.4e-41 139.6 0.0 1.5e-40 139.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Fungal_trans PF04082.13 EPS28112.1 - 1.1e-12 47.4 0.0 1.8e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ECH PF00378.15 EPS28113.1 - 7.5e-40 136.5 1.4 3.1e-39 134.5 1.0 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EPS28113.1 - 0.04 13.7 0.0 0.44 10.3 0.0 2.3 3 0 0 3 3 3 0 Peptidase family S49 PIG-F PF06699.6 EPS28114.1 - 2.2e-49 168.0 3.5 3.1e-49 167.5 2.4 1.2 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F Gly-zipper_YMGG PF13441.1 EPS28114.1 - 0.018 14.5 0.9 0.038 13.5 0.4 1.7 1 1 0 1 1 1 0 YMGG-like Gly-zipper DUF4310 PF14187.1 EPS28114.1 - 0.028 13.9 0.1 0.059 12.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4310) Gly-zipper_Omp PF13488.1 EPS28114.1 - 0.31 10.7 5.4 4.5 6.9 0.2 2.2 2 0 0 2 2 2 0 Glycine zipper Rick_17kDa_Anti PF05433.10 EPS28114.1 - 6.2 6.5 7.6 7.2 6.3 0.2 2.3 2 0 0 2 2 2 0 Glycine zipper 2TM domain RhoGAP PF00620.22 EPS28115.1 - 1.5e-38 131.8 0.0 2.2e-38 131.2 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain zf-Tim10_DDP PF02953.10 EPS28117.1 - 3.6e-20 71.0 8.6 4.7e-20 70.6 6.0 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger YqzH PF14164.1 EPS28117.1 - 0.015 15.2 0.5 0.047 13.6 0.1 1.9 1 1 1 2 2 2 0 YqzH-like protein GED PF02212.13 EPS28117.1 - 0.025 14.4 0.4 0.03 14.2 0.3 1.1 1 0 0 1 1 1 0 Dynamin GTPase effector domain DUF842 PF05811.8 EPS28117.1 - 0.094 12.1 7.6 0.14 11.5 5.2 1.4 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) PaREP1 PF05942.6 EPS28117.1 - 0.12 12.2 0.0 0.14 12.0 0.0 1.1 1 0 0 1 1 1 0 Archaeal PaREP1/PaREP8 family CDC37_N PF03234.9 EPS28117.1 - 0.75 10.0 3.0 0.92 9.8 2.1 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding ADH_N PF08240.7 EPS28118.1 - 7.9e-27 93.1 1.7 7.9e-27 93.1 1.2 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPS28118.1 - 2.2e-17 62.8 0.6 5.6e-17 61.5 0.4 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PQQ PF01011.16 EPS28118.1 - 0.029 13.9 0.1 0.072 12.6 0.1 1.6 1 0 0 1 1 1 0 PQQ enzyme repeat NAD_binding_5 PF07994.7 EPS28119.1 - 7.3e-113 376.9 0.1 8.9e-113 376.6 0.1 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 EPS28119.1 - 4.2e-46 155.3 0.5 8.1e-46 154.4 0.4 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase DUF4635 PF15466.1 EPS28119.1 - 0.088 12.0 0.0 0.64 9.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4635) zf-MYND PF01753.13 EPS28121.1 - 2.9e-08 33.4 10.6 5.7e-08 32.4 7.4 1.5 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 EPS28121.1 - 5.2 6.8 6.7 9.5 5.9 4.7 1.4 1 0 0 1 1 1 0 HIT zinc finger ADH_zinc_N PF00107.21 EPS28122.1 - 4.5e-26 90.9 0.3 6.8e-26 90.3 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPS28122.1 - 3e-21 75.2 0.7 5.1e-21 74.4 0.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EPS28122.1 - 8.7e-09 36.3 0.2 1.8e-08 35.3 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EPS28122.1 - 0.0002 21.3 0.1 0.00035 20.6 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding Glucokinase PF02685.11 EPS28122.1 - 0.026 13.3 0.2 0.043 12.5 0.2 1.3 1 0 0 1 1 1 0 Glucokinase ACP_syn_III_C PF08541.5 EPS28122.1 - 0.037 14.0 0.1 0.12 12.4 0.1 1.7 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Arf PF00025.16 EPS28123.1 - 1.8e-73 245.4 0.1 2e-73 245.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EPS28123.1 - 4e-12 45.7 0.0 4.8e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EPS28123.1 - 3.6e-11 42.7 0.0 4.2e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EPS28123.1 - 5.2e-10 38.5 0.4 4.3e-06 25.6 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EPS28123.1 - 3.6e-09 36.1 0.0 4.6e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EPS28123.1 - 1.2e-07 32.2 0.0 1.7e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EPS28123.1 - 9.5e-06 25.5 0.0 1.3e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EPS28123.1 - 2.5e-05 23.7 0.0 0.0037 16.7 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EPS28123.1 - 0.0095 15.2 0.5 0.046 13.0 0.4 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF3986 PF13143.1 EPS28123.1 - 0.075 13.4 0.1 0.18 12.3 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3986) Actin PF00022.14 EPS28124.1 - 9.3e-29 100.0 0.0 1.3e-17 63.3 0.0 2.6 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 EPS28124.1 - 2.9e-06 26.1 0.0 0.00025 19.7 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein DUF2114 PF09887.4 EPS28124.1 - 0.09 11.0 0.0 0.13 10.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2114) Paf1 PF03985.8 EPS28125.1 - 6.9e-39 133.8 0.0 4.7e-29 101.4 0.0 2.9 2 1 0 2 2 2 2 Paf1 4HBT_3 PF13622.1 EPS28125.1 - 1.4 8.5 8.0 0.15 11.8 0.8 2.5 2 1 0 2 2 2 0 Thioesterase-like superfamily DHO_dh PF01180.16 EPS28127.1 - 1.4e-65 221.1 0.1 4.6e-55 186.6 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase PcrB PF01884.12 EPS28127.1 - 4.2e-05 22.9 0.4 0.13 11.4 0.0 2.4 2 0 0 2 2 2 2 PcrB family FMN_dh PF01070.13 EPS28127.1 - 0.0061 15.4 0.0 0.1 11.4 0.0 2.2 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Dus PF01207.12 EPS28127.1 - 0.14 10.9 0.2 0.34 9.6 0.0 1.7 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) TIM PF00121.13 EPS28128.1 - 1.3e-43 148.8 0.0 1.9e-43 148.3 0.0 1.2 1 0 0 1 1 1 1 Triosephosphate isomerase LacAB_rpiB PF02502.13 EPS28129.1 - 3.7e-40 136.8 0.0 4.2e-40 136.6 0.0 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase URO-D PF01208.12 EPS28129.1 - 0.073 11.9 0.0 0.25 10.2 0.0 1.7 2 0 0 2 2 2 0 Uroporphyrinogen decarboxylase (URO-D) U-box PF04564.10 EPS28130.1 - 1e-22 79.8 0.0 1.9e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 U-box domain TPR_11 PF13414.1 EPS28130.1 - 2.5e-15 55.8 0.3 2.2e-12 46.4 0.0 3.2 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 EPS28130.1 - 1.7e-07 30.5 0.6 0.025 14.4 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EPS28130.1 - 2.1e-06 28.2 1.2 0.14 12.8 0.0 2.7 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EPS28130.1 - 2.3e-06 26.9 0.1 0.00069 19.1 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EPS28130.1 - 1.6e-05 24.7 0.3 0.047 13.6 0.1 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EPS28130.1 - 2.8e-05 24.3 0.7 0.068 13.5 0.4 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EPS28130.1 - 7.2e-05 23.0 0.8 0.22 12.2 0.5 3.2 3 1 0 3 3 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EPS28130.1 - 0.0013 18.7 0.0 2.7 8.4 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EPS28130.1 - 0.044 13.5 0.2 1.1 9.1 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.9 EPS28130.1 - 0.048 14.1 0.1 0.048 14.1 0.1 2.2 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_10 PF13374.1 EPS28130.1 - 0.088 12.7 0.4 2.2 8.3 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat ACBP PF00887.14 EPS28131.1 - 1.2e-14 53.7 0.4 2e-14 53.0 0.3 1.4 1 0 0 1 1 1 1 Acyl CoA binding protein Tyr-DNA_phospho PF06087.7 EPS28132.1 - 1.1e-121 406.6 0.0 4e-102 342.1 0.0 2.1 1 1 1 2 2 2 2 Tyrosyl-DNA phosphodiesterase DIE2_ALG10 PF04922.7 EPS28133.1 - 6.6e-76 255.7 9.4 1.4e-67 228.3 2.2 2.4 2 1 0 2 2 2 2 DIE2/ALG10 family Sld5 PF05916.6 EPS28134.1 - 1.7e-30 105.4 0.0 2.4e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein TFIIE_alpha PF02002.12 EPS28134.1 - 0.16 11.4 0.1 0.26 10.7 0.1 1.3 1 0 0 1 1 1 0 TFIIE alpha subunit CUE PF02845.11 EPS28135.1 - 1.1e-10 40.7 0.0 2e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 CUE domain SMC_N PF02463.14 EPS28136.1 - 2.2e-64 216.7 26.7 6.2e-62 208.7 18.5 3.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EPS28136.1 - 1.1e-22 80.1 1.9 3e-21 75.6 0.3 3.0 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 EPS28136.1 - 1.6e-13 51.4 10.6 1.6e-13 51.4 7.3 6.4 2 2 4 6 6 6 1 AAA domain AAA_21 PF13304.1 EPS28136.1 - 3.3e-13 50.2 9.1 7.3e-06 26.1 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EPS28136.1 - 8.1e-05 22.0 0.0 0.0002 20.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 EPS28136.1 - 0.00019 20.0 30.5 0.00019 20.0 21.1 5.3 3 2 2 5 5 5 2 AAA domain TMCO5 PF14992.1 EPS28136.1 - 0.0058 15.7 1.7 0.0058 15.7 1.2 6.5 2 2 4 6 6 6 2 TMCO5 family Reo_sigmaC PF04582.7 EPS28136.1 - 0.018 14.2 35.6 0.04 13.0 2.2 5.7 3 2 1 5 5 5 0 Reovirus sigma C capsid protein ABC_tran PF00005.22 EPS28136.1 - 0.057 13.7 0.0 0.057 13.7 0.0 5.9 3 2 1 4 4 4 0 ABC transporter Methyltransf_31 PF13847.1 EPS28137.1 - 1.4e-14 53.9 0.0 2e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPS28137.1 - 7.5e-13 48.7 0.0 1.3e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPS28137.1 - 5.1e-10 39.7 0.0 1.1e-09 38.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPS28137.1 - 5.7e-10 39.4 0.0 1.2e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPS28137.1 - 5.9e-10 38.6 0.0 1e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EPS28137.1 - 2.8e-08 33.7 0.0 5e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS28137.1 - 4.3e-06 27.2 0.0 8.9e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPS28137.1 - 1.1e-05 25.2 0.0 1.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPS28137.1 - 0.0041 16.5 0.0 0.014 14.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain NOT2_3_5 PF04153.13 EPS28138.1 - 7.1e-34 116.5 0.0 7.1e-34 116.5 0.0 2.1 3 0 0 3 3 3 1 NOT2 / NOT3 / NOT5 family MRP-L47 PF06984.8 EPS28139.1 - 1.1e-19 70.0 0.1 1.7e-19 69.4 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Clc-like PF07062.7 EPS28139.1 - 0.078 12.2 0.7 0.12 11.5 0.5 1.3 1 0 0 1 1 1 0 Clc-like GDI PF00996.13 EPS28140.1 - 6.1e-176 585.0 0.0 7.2e-176 584.7 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor 4HBT PF03061.17 EPS28141.1 - 1.2e-12 47.7 0.1 2e-12 47.0 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EPS28141.1 - 0.0024 17.6 0.1 0.0032 17.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4442 PF14539.1 EPS28141.1 - 0.11 12.5 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) ORC4_C PF14629.1 EPS28142.1 - 1.5e-54 184.4 0.0 2.7e-54 183.6 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 EPS28142.1 - 1.9e-17 63.8 0.5 2.8e-16 60.0 0.3 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 EPS28142.1 - 7e-08 32.7 0.0 2.9e-07 30.7 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EPS28142.1 - 2.6e-06 27.1 0.1 1e-05 25.2 0.1 2.0 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EPS28142.1 - 9.2e-06 25.8 0.0 2.1e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EPS28142.1 - 0.00016 21.4 0.0 0.00052 19.7 0.0 1.8 1 1 0 1 1 1 1 Archaeal ATPase DUF815 PF05673.8 EPS28142.1 - 0.00031 19.7 0.1 0.0005 19.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) KAP_NTPase PF07693.9 EPS28142.1 - 0.0034 16.4 0.0 0.0053 15.7 0.0 1.3 1 0 0 1 1 1 1 KAP family P-loop domain ABC_tran PF00005.22 EPS28142.1 - 0.015 15.6 0.0 0.035 14.4 0.0 1.7 1 0 0 1 1 1 0 ABC transporter ATP-synt_ab PF00006.20 EPS28142.1 - 0.027 13.9 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 EPS28142.1 - 0.028 13.9 0.1 0.072 12.5 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_14 PF13173.1 EPS28142.1 - 0.032 14.1 0.0 0.16 11.8 0.0 2.2 2 1 0 2 2 2 0 AAA domain RGS PF00615.14 EPS28146.1 - 3.4e-34 117.4 0.1 8.9e-34 116.1 0.0 1.8 1 0 0 1 1 1 1 Regulator of G protein signaling domain DEP PF00610.16 EPS28146.1 - 5.3e-25 86.9 0.0 1.2e-18 66.6 0.0 3.2 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) CDC73 PF05179.9 EPS28149.1 - 7.3e-41 140.3 0.0 1.9e-40 138.9 0.0 1.7 1 1 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family SET PF00856.23 EPS28150.1 - 9.5e-06 26.0 0.1 9.5e-06 26.0 0.1 3.0 4 0 0 4 4 4 1 SET domain PHD PF00628.24 EPS28150.1 - 1.1e-05 24.9 8.3 2.4e-05 23.9 5.8 1.6 1 0 0 1 1 1 1 PHD-finger WD40 PF00400.27 EPS28152.1 - 1.3e-25 88.3 8.1 8.2e-07 28.6 0.0 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat Glycos_transf_4 PF00953.16 EPS28153.1 - 5e-32 110.8 12.4 5e-32 110.8 8.6 2.5 2 1 0 2 2 2 1 Glycosyl transferase family 4 DUF4267 PF14087.1 EPS28154.1 - 6.5e-07 28.9 2.2 9.8e-07 28.3 1.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DUF3425 PF11905.3 EPS28155.1 - 8.8e-21 74.2 1.2 1.3e-20 73.7 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Aconitase PF00330.15 EPS28156.1 - 1.1e-183 611.0 0.1 1.3e-183 610.7 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EPS28156.1 - 8.3e-43 145.6 0.0 1.7e-42 144.6 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Glyco_transf_5 PF08323.6 EPS28157.1 - 1.7e-12 47.3 0.2 2.9e-12 46.5 0.1 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain Alpha-amylase PF00128.19 EPS28157.1 - 9.2e-09 35.1 1.2 1.5e-07 31.1 0.0 3.3 3 1 0 3 3 3 1 Alpha amylase, catalytic domain Glyco_trans_1_4 PF13692.1 EPS28157.1 - 0.00012 22.2 0.0 0.00028 21.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 EPS28157.1 - 0.00032 20.1 0.0 0.00069 19.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Pribosyltran PF00156.22 EPS28158.1 - 2.6e-15 56.2 0.4 4.9e-15 55.3 0.2 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain MTHFR PF02219.12 EPS28159.1 - 6e-117 389.8 0.0 8.7e-117 389.2 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase ComA PF02679.10 EPS28159.1 - 0.17 10.8 0.0 0.31 9.9 0.0 1.4 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) DUF2418 PF10332.4 EPS28161.1 - 4.8e-34 116.6 0.5 9.4e-34 115.6 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) ATP-synt_F PF01990.12 EPS28162.1 - 3.4e-31 107.5 0.1 3.9e-31 107.2 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit E1_DerP2_DerF2 PF02221.10 EPS28164.1 - 6.3e-27 94.4 0.2 7.6e-27 94.1 0.1 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 EPS28164.1 - 0.00094 19.2 0.1 0.0017 18.3 0.0 1.5 1 1 0 1 1 1 1 ML-like domain Glyco_hydro_17 PF00332.13 EPS28166.1 - 3.3e-06 26.3 0.7 5.7e-06 25.5 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Thiolase_N PF00108.18 EPS28167.1 - 1.4e-67 227.4 0.3 2.5e-67 226.6 0.2 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EPS28167.1 - 4.9e-43 145.4 0.2 1.1e-42 144.3 0.1 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EPS28167.1 - 0.001 18.6 0.7 0.025 14.2 0.1 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 EPS28167.1 - 0.0094 15.4 0.9 0.044 13.2 0.8 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.5 EPS28167.1 - 0.026 14.5 0.0 0.11 12.5 0.0 2.1 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal AMP-binding PF00501.23 EPS28168.1 - 1e-64 218.4 0.0 1.4e-64 218.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPS28168.1 - 1.3e-05 26.0 0.0 2.8e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DIOX_N PF14226.1 EPS28170.1 - 4.4e-32 111.0 0.0 6.5e-30 104.0 0.0 2.3 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal Abhydrolase_6 PF12697.2 EPS28170.1 - 5.1e-19 69.0 0.0 9.7e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family 2OG-FeII_Oxy PF03171.15 EPS28170.1 - 3.9e-12 46.3 0.0 8.4e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Abhydrolase_5 PF12695.2 EPS28170.1 - 5.3e-09 35.9 0.0 8.2e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EPS28170.1 - 3.6e-05 23.4 0.0 0.00011 21.8 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) DUF2305 PF10230.4 EPS28170.1 - 8.5e-05 22.0 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Thioesterase PF00975.15 EPS28170.1 - 0.00018 21.7 0.0 0.00088 19.5 0.0 1.9 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_1 PF00561.15 EPS28170.1 - 0.00031 20.3 0.0 0.00049 19.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EPS28170.1 - 0.0029 17.2 0.0 0.0045 16.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 EPS28170.1 - 0.0038 16.8 0.0 0.0072 15.9 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Esterase PF00756.15 EPS28170.1 - 0.0093 15.4 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 EPS28170.1 - 0.018 14.5 0.0 0.22 10.9 0.0 2.5 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase DUF2974 PF11187.3 EPS28170.1 - 0.16 11.3 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) APH PF01636.18 EPS28171.1 - 3e-19 69.7 0.0 6.9e-19 68.5 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 EPS28171.1 - 4.3e-06 25.9 0.3 0.0011 18.0 0.0 2.2 2 0 0 2 2 2 2 Fructosamine kinase ATG22 PF11700.3 EPS28172.1 - 8.8e-133 443.2 31.0 1e-132 443.0 21.5 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like Phage_holin_1 PF04531.8 EPS28172.1 - 4 7.5 7.2 0.41 10.7 0.6 2.6 2 1 1 3 3 3 0 Bacteriophage holin FAD_binding_3 PF01494.14 EPS28173.1 - 5.6e-75 252.6 0.0 7.6e-75 252.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EPS28173.1 - 6.9e-05 22.9 0.0 0.009 16.0 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EPS28173.1 - 0.00014 20.8 0.2 0.24 10.2 0.0 2.5 1 1 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EPS28173.1 - 0.011 14.9 0.1 0.13 11.2 0.0 2.4 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EPS28173.1 - 0.053 13.5 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EPS28173.1 - 0.055 13.3 0.0 0.41 10.5 0.0 2.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPS28173.1 - 0.079 13.3 0.0 3 8.3 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EPS28173.1 - 0.11 11.3 0.1 0.24 10.1 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain Sugar_tr PF00083.19 EPS28175.1 - 2.9e-128 428.2 19.8 3.3e-128 428.1 13.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS28175.1 - 4.3e-26 91.4 26.8 1.3e-19 70.1 7.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EPS28175.1 - 2.9e-07 29.2 25.9 0.0036 15.7 0.9 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 EPS28175.1 - 0.014 13.5 11.6 0.0073 14.5 1.2 2.1 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 EPS28175.1 - 0.43 10.3 4.4 3 7.7 0.2 3.3 3 0 0 3 3 3 0 MFS_1 like family KH_1 PF00013.24 EPS28176.1 - 0.0013 18.3 0.0 0.004 16.7 0.0 1.9 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EPS28176.1 - 0.018 14.6 0.0 0.13 11.9 0.0 2.3 2 0 0 2 2 2 0 KH domain GAGA_bind PF06217.7 EPS28176.1 - 3.9 7.3 17.2 5.2 6.9 11.9 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Methyltransf_23 PF13489.1 EPS28177.1 - 2.5e-11 43.5 0.0 4.2e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPS28177.1 - 3.7e-09 36.9 0.0 8.7e-09 35.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPS28177.1 - 7.2e-07 29.6 0.0 1.7e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPS28177.1 - 0.00045 19.8 0.0 0.14 11.7 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 EPS28177.1 - 0.00052 20.3 0.0 0.0028 17.9 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS28177.1 - 0.0019 18.7 0.1 0.024 15.2 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_29 PF03141.11 EPS28177.1 - 0.021 13.1 0.1 0.1 10.8 0.0 1.8 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.13 EPS28177.1 - 0.11 11.5 0.0 0.64 9.0 0.0 2.1 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Spc97_Spc98 PF04130.8 EPS28179.1 - 4.5e-136 454.3 2.0 5.6e-136 454.0 1.4 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family Proteasome PF00227.21 EPS28180.1 - 2.5e-57 193.2 0.1 3.1e-57 192.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EPS28180.1 - 9e-14 50.4 0.2 2.3e-13 49.2 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Fungal_trans PF04082.13 EPS28181.1 - 2.3e-19 69.2 2.4 3.5e-19 68.7 1.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Methyltransf_8 PF05148.10 EPS28182.1 - 1.1e-54 185.4 0.0 1.1e-52 178.9 0.0 2.7 3 0 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 EPS28182.1 - 2.6e-07 31.0 0.1 1.4e-06 28.6 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Macoilin PF09726.4 EPS28182.1 - 0.018 13.3 8.8 0.021 13.1 6.1 1.2 1 0 0 1 1 1 0 Transmembrane protein Methyltransf_25 PF13649.1 EPS28182.1 - 0.021 15.1 0.0 1.7 9.0 0.0 2.5 1 1 0 1 1 1 0 Methyltransferase domain SR-25 PF10500.4 EPS28182.1 - 1.9 7.9 31.0 0.93 8.9 14.3 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Fungal_trans_2 PF11951.3 EPS28183.1 - 1.1e-17 63.7 0.0 4.3e-16 58.5 0.0 2.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS28183.1 - 2e-06 27.5 8.4 4.3e-06 26.5 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BAR_2 PF10455.4 EPS28185.1 - 8.3e-63 211.9 3.0 1.2e-62 211.4 2.1 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 EPS28185.1 - 1.2e-20 74.0 7.7 1.5e-19 70.4 5.3 2.0 1 1 0 1 1 1 1 BAR domain ATP-synt_B PF00430.13 EPS28185.1 - 0.0021 17.8 4.1 0.0021 17.8 2.9 2.3 3 0 0 3 3 3 1 ATP synthase B/B' CF(0) GAS PF13851.1 EPS28185.1 - 0.28 10.3 8.1 0.32 10.1 0.3 2.4 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding ATP_synt_H PF05493.8 EPS28186.1 - 7.2e-26 90.0 4.2 7.8e-26 89.9 2.9 1.0 1 0 0 1 1 1 1 ATP synthase subunit H OppC_N PF12911.2 EPS28186.1 - 0.00099 18.4 0.4 0.54 9.6 0.1 2.1 2 0 0 2 2 2 2 N-terminal TM domain of oligopeptide transport permease C Git3 PF11710.3 EPS28186.1 - 0.018 14.6 0.1 0.02 14.4 0.1 1.0 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 DUF4131 PF13567.1 EPS28186.1 - 0.031 13.6 3.2 0.033 13.5 2.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Bax1-I PF01027.15 EPS28186.1 - 0.04 13.5 1.8 0.05 13.2 1.2 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Pox_A14 PF05767.7 EPS28186.1 - 0.065 13.1 0.5 0.073 13.0 0.3 1.1 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 MgtE PF01769.11 EPS28186.1 - 0.069 13.4 0.5 0.085 13.1 0.4 1.0 1 0 0 1 1 1 0 Divalent cation transporter YfhO PF09586.5 EPS28186.1 - 0.089 10.8 0.8 0.089 10.8 0.6 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO EamA PF00892.15 EPS28186.1 - 0.11 12.5 4.3 0.13 12.3 3.0 1.1 1 0 0 1 1 1 0 EamA-like transporter family DUF1129 PF06570.6 EPS28186.1 - 0.13 11.5 0.8 0.15 11.3 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) 5TM-5TMR_LYT PF07694.7 EPS28186.1 - 0.27 10.5 2.3 0.29 10.4 1.6 1.0 1 0 0 1 1 1 0 5TMR of 5TMR-LYT ABC2_membrane_4 PF12730.2 EPS28186.1 - 0.27 10.3 5.1 0.35 10.0 3.6 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein Arv1 PF04161.8 EPS28187.1 - 7.5e-42 143.5 0.0 4.4e-36 124.7 0.0 2.2 2 0 0 2 2 2 2 Arv1-like family DUF619 PF04768.8 EPS28188.1 - 2.1e-52 176.9 0.0 3.4e-51 173.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF619) PEP_mutase PF13714.1 EPS28188.1 - 0.013 14.7 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase Rep_4 PF05797.6 EPS28188.1 - 0.038 12.7 0.1 0.08 11.6 0.1 1.4 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) Sua5_yciO_yrdC PF01300.13 EPS28188.1 - 0.041 13.1 0.1 0.11 11.7 0.1 1.8 1 0 0 1 1 1 0 Telomere recombination Acetyltransf_1 PF00583.19 EPS28189.1 - 1.2e-11 44.4 0.0 1.9e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPS28189.1 - 3.9e-09 36.5 0.0 6.5e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPS28189.1 - 0.00024 20.9 0.0 0.00063 19.5 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EPS28189.1 - 0.0034 17.2 0.0 0.0067 16.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPS28189.1 - 0.0049 16.5 0.0 0.0079 15.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 EPS28189.1 - 0.0069 16.3 0.0 0.17 11.8 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPS28189.1 - 0.085 12.9 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NOGCT PF08155.6 EPS28190.1 - 1.5e-28 98.2 1.3 3.2e-28 97.1 0.9 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 EPS28190.1 - 5.2e-27 93.5 0.7 1.4e-26 92.1 0.5 1.8 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 EPS28190.1 - 3.9e-15 55.8 0.0 8.7e-15 54.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EPS28190.1 - 2.4e-07 30.1 0.0 6e-07 28.8 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EPS28190.1 - 8.1e-05 23.1 0.0 0.0011 19.4 0.0 2.5 1 1 1 2 2 2 1 Miro-like protein Sigma54_activ_2 PF14532.1 EPS28190.1 - 0.0056 16.7 0.0 0.016 15.2 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain Dynamin_N PF00350.18 EPS28190.1 - 0.0084 15.9 0.0 5.2 6.8 0.0 2.6 1 1 1 2 2 2 2 Dynamin family Hydrolase_4 PF12146.3 EPS28191.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative lysophospholipase SHP PF03579.8 EPS28192.1 - 2.5 7.5 9.1 12 5.3 0.0 3.7 3 1 1 4 4 4 0 Small hydrophobic protein DUF4149 PF13664.1 EPS28192.1 - 6.5 6.8 9.1 1.2 9.2 1.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) Sugar_tr PF00083.19 EPS28194.1 - 1.7e-139 465.3 34.7 1.9e-139 465.1 24.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS28194.1 - 7.7e-25 87.3 60.3 1.1e-21 77.0 22.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.4 EPS28194.1 - 0.0056 16.6 0.9 0.031 14.2 0.6 2.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2530) NAD_binding_2 PF03446.10 EPS28195.1 - 1e-30 106.7 0.2 1.5e-30 106.1 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EPS28195.1 - 1.3e-11 44.7 0.1 3.4e-11 43.4 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EPS28195.1 - 2.2e-08 34.2 0.0 3.6e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_11 PF14833.1 EPS28195.1 - 9.7e-08 32.1 1.1 5.2e-07 29.7 0.2 2.5 2 1 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Semialdhyde_dh PF01118.19 EPS28195.1 - 0.00025 21.3 0.0 0.00044 20.5 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain OCD_Mu_crystall PF02423.10 EPS28195.1 - 0.011 14.5 0.1 0.018 13.8 0.0 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family IlvN PF07991.7 EPS28195.1 - 0.011 15.1 0.0 0.045 13.1 0.0 1.9 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.14 EPS28195.1 - 0.03 13.4 0.0 0.046 12.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 EPS28195.1 - 0.036 14.4 0.0 0.1 12.9 0.0 1.8 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EPS28195.1 - 0.036 13.0 0.0 0.064 12.2 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_Gly3P_dh_N PF01210.18 EPS28195.1 - 0.061 13.0 0.2 0.12 12.1 0.1 1.5 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GFO_IDH_MocA PF01408.17 EPS28195.1 - 0.096 13.2 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold UDPG_MGDP_dh_N PF03721.9 EPS28195.1 - 0.097 12.0 0.3 1.3 8.3 0.0 2.3 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DSBA PF01323.15 EPS28197.1 - 3.8e-17 62.4 0.0 4.7e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain MFS_1 PF07690.11 EPS28198.1 - 8.2e-40 136.5 42.4 8.2e-40 136.5 29.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS28198.1 - 3.4e-05 22.6 18.1 3.4e-05 22.6 12.5 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter Cofilin_ADF PF00241.15 EPS28198.1 - 0.025 14.4 0.0 0.41 10.5 0.0 2.2 2 0 0 2 2 2 0 Cofilin/tropomyosin-type actin-binding protein DDRGK PF09756.4 EPS28199.1 - 0.048 13.0 29.9 0.054 12.9 20.7 1.1 1 0 0 1 1 1 0 DDRGK domain MIP-T3 PF10243.4 EPS28199.1 - 0.18 10.2 36.1 0.18 10.2 25.0 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 TFIIF_alpha PF05793.7 EPS28199.1 - 0.25 9.6 27.3 0.26 9.6 18.9 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Vfa1 PF08432.5 EPS28199.1 - 0.37 10.8 29.7 0.4 10.6 20.6 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 eIF3_subunit PF08597.5 EPS28199.1 - 0.77 9.2 25.4 0.95 8.9 17.6 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit GAGA_bind PF06217.7 EPS28199.1 - 1.3 8.9 21.4 1.5 8.7 14.9 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Tir_receptor_N PF07490.6 EPS28199.1 - 1.4 8.4 6.7 1.6 8.2 4.6 1.1 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus YL1 PF05764.8 EPS28199.1 - 1.6 8.2 34.5 1.8 8.1 23.9 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Pox_Ag35 PF03286.9 EPS28199.1 - 1.7 8.1 25.8 2 7.8 17.9 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Tim54 PF11711.3 EPS28199.1 - 2.2 6.8 12.9 2.2 6.7 8.9 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF1777 PF08648.7 EPS28199.1 - 2.2 7.9 31.1 2.4 7.8 21.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) CDC45 PF02724.9 EPS28199.1 - 2.5 6.0 20.9 2.8 5.8 14.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2413 PF10310.4 EPS28199.1 - 3 6.5 24.2 3 6.5 16.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Draxin PF15550.1 EPS28199.1 - 3 7.3 20.5 3.4 7.2 14.2 1.1 1 0 0 1 1 1 0 Draxin SRP-alpha_N PF04086.8 EPS28199.1 - 3.3 7.0 27.1 3.8 6.8 18.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Atrophin-1 PF03154.10 EPS28199.1 - 3.5 5.6 26.1 3.9 5.5 18.1 1.0 1 0 0 1 1 1 0 Atrophin-1 family FAM60A PF15396.1 EPS28199.1 - 4.4 7.0 25.4 5.6 6.6 17.6 1.2 1 0 0 1 1 1 0 Protein Family FAM60A FLO_LFY PF01698.11 EPS28199.1 - 5.7 5.6 17.0 6.1 5.5 11.8 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein ELL PF10390.4 EPS28199.1 - 5.8 6.0 25.2 6.2 5.9 17.5 1.1 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL Ctr PF04145.10 EPS28199.1 - 6 6.9 9.8 7.5 6.5 6.8 1.3 1 0 0 1 1 1 0 Ctr copper transporter family LicD PF04991.8 EPS28199.1 - 6.2 6.8 15.6 6.6 6.7 10.8 1.1 1 0 0 1 1 1 0 LicD family BTV_NS2 PF04514.7 EPS28199.1 - 8 5.2 16.3 7.7 5.2 11.3 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF4207 PF13904.1 EPS28199.1 - 8.3 5.6 33.9 9.6 5.4 23.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4207) eIF-3_zeta PF05091.7 EPS28199.1 - 9.2 4.7 18.1 9 4.7 12.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) BSMAP PF12280.3 EPS28199.1 - 9.4 6.0 13.4 11 5.7 9.3 1.2 1 0 0 1 1 1 0 Brain specific membrane anchored protein GalP_UDP_transf PF01087.17 EPS28201.1 - 7.4e-69 231.4 0.8 3.9e-67 225.8 0.2 2.9 3 0 0 3 3 3 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 EPS28201.1 - 5.3e-57 191.9 0.1 1.3e-56 190.7 0.0 1.6 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain DAO PF01266.19 EPS28202.1 - 3.4e-32 111.7 0.1 4.7e-32 111.2 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPS28202.1 - 0.00058 18.8 0.0 0.001 17.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EPS28202.1 - 0.0009 19.2 0.0 0.0027 17.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EPS28202.1 - 0.0017 18.7 0.2 0.0042 17.4 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF1188 PF06690.6 EPS28202.1 - 0.0085 15.2 0.0 1.2 8.2 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1188) Shikimate_DH PF01488.15 EPS28202.1 - 0.022 14.8 0.3 0.27 11.3 0.1 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.1 EPS28202.1 - 0.031 14.3 0.0 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EPS28202.1 - 0.035 13.1 0.7 0.072 12.1 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain ApbA PF02558.11 EPS28202.1 - 0.043 13.2 0.3 0.12 11.7 0.1 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 EPS28202.1 - 0.045 13.9 0.0 0.077 13.2 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_2 PF07992.9 EPS28202.1 - 0.048 13.5 0.0 0.084 12.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPS28202.1 - 0.058 12.4 0.1 0.13 11.3 0.1 1.6 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 EPS28202.1 - 0.13 10.8 0.3 0.35 9.4 0.1 1.7 2 0 0 2 2 2 0 Tryptophan halogenase UDPG_MGDP_dh_N PF03721.9 EPS28202.1 - 0.17 11.2 0.1 0.31 10.4 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Erg28 PF03694.8 EPS28203.1 - 3.5e-35 120.3 0.2 4.2e-35 120.1 0.2 1.1 1 0 0 1 1 1 1 Erg28 like protein G2F PF07474.7 EPS28203.1 - 0.11 11.7 0.1 5.8 6.2 0.0 2.0 2 0 0 2 2 2 0 G2F domain adh_short PF00106.20 EPS28204.1 - 9.4e-20 71.1 0.1 2e-19 70.1 0.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPS28204.1 - 7.8e-11 42.1 0.0 1.1e-10 41.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPS28204.1 - 1.3e-05 24.9 0.1 2.5e-05 24.0 0.1 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EPS28204.1 - 0.0046 16.9 0.0 0.0073 16.3 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EPS28204.1 - 0.0085 15.0 0.1 0.011 14.6 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein p53-inducible11 PF14936.1 EPS28205.1 - 0.24 11.3 4.5 0.52 10.2 3.1 1.6 1 0 0 1 1 1 0 Tumour protein p53-inducible protein 11 Dicistro_VP4 PF11492.3 EPS28206.1 - 0.012 15.6 1.3 55 3.8 0.0 4.5 3 1 1 4 4 4 0 Cricket paralysis virus, VP4 CoA_binding_2 PF13380.1 EPS28208.1 - 4.3e-27 94.5 0.0 5.6e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain Rad4 PF03835.10 EPS28209.1 - 8.7e-37 125.7 0.0 8.7e-37 125.7 0.0 1.9 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 EPS28209.1 - 9.5e-29 98.9 0.0 1.6e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 EPS28209.1 - 8e-18 63.7 0.0 1.7e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EPS28209.1 - 2.6e-17 62.8 0.1 2.6e-17 62.8 0.0 2.9 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 EPS28209.1 - 0.0058 16.8 0.0 0.015 15.5 0.0 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily HAUS6_N PF14661.1 EPS28210.1 - 3.8e-51 173.8 0.6 6.5e-51 173.0 0.4 1.3 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus HD_3 PF13023.1 EPS28211.1 - 9.3e-47 158.8 0.2 1.1e-46 158.5 0.2 1.1 1 0 0 1 1 1 1 HD domain HIT PF01230.18 EPS28212.1 - 5.8e-24 84.4 0.1 8.7e-24 83.9 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EPS28212.1 - 5.6e-07 29.8 0.0 8.4e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Mob1_phocein PF03637.12 EPS28213.1 - 1.1e-26 93.5 0.1 1.9e-26 92.7 0.0 1.3 1 0 0 1 1 1 1 Mob1/phocein family cobW PF02492.14 EPS28214.1 - 3.8e-45 153.5 0.1 5.4e-45 152.9 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EPS28214.1 - 3.8e-05 23.3 0.0 7.2e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain Arch_ATPase PF01637.13 EPS28214.1 - 0.0015 18.3 0.0 0.0023 17.6 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 EPS28214.1 - 0.0024 17.9 0.0 0.0064 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 EPS28214.1 - 0.025 14.8 0.4 0.073 13.3 0.1 1.8 2 0 0 2 2 1 0 AAA domain GTP_EFTU PF00009.22 EPS28214.1 - 0.03 13.7 0.4 1.8 7.9 0.0 2.3 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain ArgK PF03308.11 EPS28214.1 - 0.031 13.0 0.9 0.32 9.7 0.0 2.5 3 0 0 3 3 3 0 ArgK protein MMR_HSR1 PF01926.18 EPS28214.1 - 0.032 14.1 0.1 0.082 12.8 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.1 EPS28214.1 - 0.033 13.7 0.1 0.1 12.1 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain MobB PF03205.9 EPS28214.1 - 0.034 13.8 0.1 0.063 12.9 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EPS28214.1 - 0.038 14.1 0.2 0.14 12.3 0.0 2.0 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.1 EPS28214.1 - 0.045 13.6 0.0 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EPS28214.1 - 0.047 13.1 0.0 0.095 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_23 PF13476.1 EPS28214.1 - 0.057 13.7 0.0 0.093 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EPS28214.1 - 0.058 12.2 0.1 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ATP_bind_1 PF03029.12 EPS28214.1 - 0.061 12.8 0.2 1.4 8.3 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_19 PF13245.1 EPS28214.1 - 0.071 12.8 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain DUF258 PF03193.11 EPS28214.1 - 0.075 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 EPS28214.1 - 0.084 13.1 0.1 0.35 11.1 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Zeta_toxin PF06414.7 EPS28214.1 - 0.092 11.8 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Pkinase PF00069.20 EPS28215.1 - 1.8e-11 43.6 0.0 7.2e-10 38.4 0.0 2.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS28215.1 - 2.4e-11 43.1 0.0 2.1e-10 40.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Lon_C PF05362.8 EPS28216.1 - 1.6e-64 216.9 0.0 2.9e-64 216.1 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EPS28216.1 - 3.4e-35 121.5 0.0 7.9e-35 120.3 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EPS28216.1 - 5.9e-22 78.2 0.0 1.3e-21 77.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EPS28216.1 - 2.8e-07 30.3 0.0 5.6e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 EPS28216.1 - 5.2e-07 29.1 0.0 1.3e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.9 EPS28216.1 - 2.3e-06 27.6 0.1 7.5e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EPS28216.1 - 5.3e-06 26.6 0.1 0.0001 22.4 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.6 EPS28216.1 - 1.2e-05 24.2 0.2 2.5e-05 23.1 0.0 1.6 2 0 0 2 2 2 1 PrkA AAA domain AAA_16 PF13191.1 EPS28216.1 - 1.5e-05 25.0 0.3 0.00024 21.1 0.0 2.8 2 1 0 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 EPS28216.1 - 8.3e-05 23.4 0.0 0.00032 21.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EPS28216.1 - 0.00045 19.3 0.0 0.0019 17.2 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EPS28216.1 - 0.0028 17.5 0.0 0.0067 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPS28216.1 - 0.0059 16.9 1.8 0.036 14.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain NTPase_1 PF03266.10 EPS28216.1 - 0.029 14.0 0.1 0.3 10.8 0.0 2.4 1 1 1 2 2 2 0 NTPase ATP-synt_ab PF00006.20 EPS28216.1 - 0.033 13.6 0.0 0.2 11.1 0.0 2.2 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.12 EPS28216.1 - 0.051 12.9 0.0 0.14 11.5 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF258 PF03193.11 EPS28216.1 - 0.079 12.1 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 EPS28216.1 - 0.14 12.3 0.0 0.39 10.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase CTDII PF01556.13 EPS28217.1 - 5.7e-29 99.8 0.7 2.8e-20 72.0 0.1 3.3 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 EPS28217.1 - 1e-23 82.8 3.7 1.8e-23 82.0 2.5 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EPS28217.1 - 2.3e-11 43.5 19.0 4.9e-11 42.5 13.2 1.6 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EPS28217.1 - 0.9 9.2 7.2 4.1 7.1 0.4 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family BRO1 PF03097.13 EPS28218.1 - 1.1e-128 429.1 5.9 1.1e-128 429.1 4.1 2.2 3 0 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EPS28218.1 - 5.7e-98 327.5 18.2 1.1e-97 326.6 12.6 1.5 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF416 PF04222.7 EPS28218.1 - 0.003 16.7 1.4 0.43 9.6 0.1 3.0 2 0 0 2 2 2 2 Protein of unknown function (DUF416) BLOC1_2 PF10046.4 EPS28218.1 - 0.57 10.3 8.2 0.12 12.4 0.9 3.5 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 adh_short PF00106.20 EPS28219.1 - 2.1e-11 44.0 0.1 8.8e-11 41.9 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EPS28219.1 - 1.1e-08 34.8 0.0 1.9e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EPS28219.1 - 0.019 14.9 0.0 0.44 10.5 0.0 2.6 2 1 0 2 2 2 0 NADH(P)-binding NAD_binding_4 PF07993.7 EPS28219.1 - 0.086 11.7 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein SAP30_Sin3_bdg PF13867.1 EPS28220.1 - 1.5e-15 56.7 0.1 1e-13 50.9 0.0 2.3 2 0 0 2 2 2 2 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF3114 PF11311.3 EPS28220.1 - 0.053 12.8 0.1 0.074 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3114) VDE PF07137.6 EPS28221.1 - 0.0076 16.1 0.1 0.0096 15.7 0.1 1.1 1 0 0 1 1 1 1 Violaxanthin de-epoxidase (VDE) zf-H2C2_2 PF13465.1 EPS28222.1 - 9.6e-10 38.2 16.3 1.1e-05 25.4 2.3 4.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 EPS28222.1 - 1.4e-07 31.4 16.5 0.0013 18.9 1.3 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPS28222.1 - 0.00019 21.5 16.7 0.013 15.7 1.1 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EPS28222.1 - 4.9 7.4 7.7 0.4 10.9 0.2 2.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 EPS28223.1 - 1.5 9.2 6.3 0.26 11.6 1.3 2.0 2 0 0 2 2 2 0 Zinc-finger double domain LSM PF01423.17 EPS28224.1 - 7.2e-14 51.0 0.1 1.2e-13 50.3 0.1 1.4 1 0 0 1 1 1 1 LSM domain Atrophin-1 PF03154.10 EPS28224.1 - 0.43 8.6 5.1 0.57 8.2 3.6 1.1 1 0 0 1 1 1 0 Atrophin-1 family NUC173 PF08161.7 EPS28225.1 - 3.3e-78 261.6 0.0 6.6e-77 257.3 0.0 2.6 2 0 0 2 2 2 1 NUC173 domain HEAT PF02985.17 EPS28225.1 - 0.053 13.6 0.8 39 4.6 0.0 4.3 4 0 0 4 4 4 0 HEAT repeat Vps35 PF03635.12 EPS28225.1 - 0.076 11.1 0.1 0.13 10.3 0.1 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 35 HEAT_2 PF13646.1 EPS28225.1 - 0.25 11.6 5.7 1.5 9.1 0.1 4.1 4 0 0 4 4 4 0 HEAT repeats Nop14 PF04147.7 EPS28225.1 - 1.3 6.8 8.8 2.9 5.7 6.1 1.5 1 0 0 1 1 1 0 Nop14-like family TPR_1 PF00515.23 EPS28231.1 - 2.6e-51 169.2 25.9 4.2e-08 32.4 0.0 11.3 10 2 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.12 EPS28231.1 - 7.2e-47 153.5 17.3 1.4e-05 24.6 0.0 10.9 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_11 PF13414.1 EPS28231.1 - 1.5e-44 149.4 18.6 1.8e-10 40.2 0.3 6.4 3 2 3 7 7 7 7 TPR repeat TPR_8 PF13181.1 EPS28231.1 - 9.3e-39 128.3 20.0 2.7e-05 23.6 0.6 10.3 8 1 2 10 10 10 9 Tetratricopeptide repeat TPR_16 PF13432.1 EPS28231.1 - 6.4e-32 109.5 7.6 6e-07 29.9 0.1 6.6 4 2 1 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 EPS28231.1 - 3.7e-30 103.7 20.5 1.5e-07 31.2 0.3 7.5 2 2 5 8 8 8 7 Tetratricopeptide repeat TPR_14 PF13428.1 EPS28231.1 - 2.6e-27 92.8 9.4 2.6e-05 24.4 0.0 9.4 2 2 8 10 10 10 8 Tetratricopeptide repeat TPR_17 PF13431.1 EPS28231.1 - 4.7e-26 88.7 18.5 0.00021 21.2 0.0 9.6 11 0 0 11 11 9 6 Tetratricopeptide repeat TPR_19 PF14559.1 EPS28231.1 - 2.6e-22 78.9 14.0 8.4e-05 22.8 0.0 7.2 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_6 PF13174.1 EPS28231.1 - 1.8e-20 71.9 16.6 0.012 16.0 0.0 10.3 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_7 PF13176.1 EPS28231.1 - 2.4e-20 70.6 12.3 0.0078 15.9 0.1 9.8 9 1 0 9 9 9 3 Tetratricopeptide repeat TPR_9 PF13371.1 EPS28231.1 - 3.2e-15 55.7 8.9 0.0028 17.4 0.0 6.9 3 2 5 8 8 8 5 Tetratricopeptide repeat Apc3 PF12895.2 EPS28231.1 - 5.5e-12 45.6 10.6 1.8e-08 34.3 1.6 4.1 3 1 1 4 4 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 EPS28231.1 - 1.1e-07 31.1 9.6 0.00014 21.0 1.7 4.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_21 PF09976.4 EPS28231.1 - 0.00031 20.7 8.8 0.61 10.0 2.6 4.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.1 EPS28231.1 - 0.0016 18.4 0.2 0.46 10.6 0.0 4.0 2 1 2 4 4 4 1 Tetratricopeptide repeat DUF2225 PF09986.4 EPS28231.1 - 0.0022 17.5 5.0 0.71 9.2 0.0 3.1 3 1 0 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) BTAD PF03704.12 EPS28231.1 - 0.023 15.0 5.3 2.4 8.4 0.0 3.6 3 0 0 3 3 3 0 Bacterial transcriptional activator domain TPR_10 PF13374.1 EPS28231.1 - 0.047 13.6 8.6 19 5.3 0.1 6.0 6 0 0 6 6 5 0 Tetratricopeptide repeat MIT PF04212.13 EPS28231.1 - 0.29 11.0 17.0 1.5 8.7 1.3 5.3 5 1 0 5 5 4 0 MIT (microtubule interacting and transport) domain Ribosomal_L3 PF00297.17 EPS28232.1 - 9.2e-118 392.3 7.9 1.1e-117 392.1 5.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 SKN1 PF03935.10 EPS28235.1 - 1.1e-214 713.2 1.3 1.7e-214 712.6 0.9 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Chorismate_bind PF00425.13 EPS28236.1 - 7.4e-64 215.5 0.0 3.3e-63 213.4 0.0 1.8 2 0 0 2 2 2 1 chorismate binding enzyme Methyltransf_31 PF13847.1 EPS28237.1 - 6e-09 35.6 0.0 8.7e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPS28237.1 - 7.1e-08 32.8 0.0 2.3e-07 31.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPS28237.1 - 2.7e-07 30.4 0.0 4.9e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPS28237.1 - 1.2e-05 25.7 0.0 2.8e-05 24.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS28237.1 - 0.00093 19.7 0.0 0.0034 17.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPS28237.1 - 0.0067 15.5 0.0 0.011 14.9 0.0 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EPS28237.1 - 0.013 15.8 0.0 0.029 14.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EPS28237.1 - 0.022 14.8 0.0 0.043 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 EPS28237.1 - 0.17 11.8 0.0 0.54 10.2 0.0 1.8 1 1 0 1 1 1 0 FtsJ-like methyltransferase Cytadhesin_P30 PF07271.6 EPS28238.1 - 0.041 13.1 0.6 0.058 12.6 0.4 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 BCDHK_Adom3 PF10436.4 EPS28239.1 - 3.5e-70 234.7 0.0 4.9e-70 234.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EPS28239.1 - 1.5e-17 63.3 0.0 2.8e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EPS28239.1 - 0.025 14.2 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Crust_neurohorm PF01147.12 EPS28239.1 - 0.15 11.4 0.1 0.34 10.2 0.0 1.5 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family DUF2948 PF11164.3 EPS28240.1 - 0.0085 15.7 2.0 0.067 12.8 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2948) Lyase_1 PF00206.15 EPS28243.1 - 9.3e-22 77.5 0.0 2e-21 76.5 0.0 1.5 2 0 0 2 2 2 1 Lyase ADSL_C PF10397.4 EPS28243.1 - 6.9e-16 58.0 0.2 3.2e-15 55.8 0.0 2.2 3 0 0 3 3 3 1 Adenylosuccinate lyase C-terminus Lyase_N PF09092.6 EPS28243.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Lyase, N terminal Exo70 PF03081.10 EPS28244.1 - 2.9e-70 236.9 0.0 5.9e-70 235.9 0.0 1.5 2 0 0 2 2 2 1 Exo70 exocyst complex subunit TPD52 PF04201.10 EPS28244.1 - 0.068 12.8 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 Tumour protein D52 family PLA2_B PF01735.13 EPS28245.1 - 2.7e-28 98.4 0.0 4.7e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 Lysophospholipase catalytic domain DSPc PF00782.15 EPS28246.1 - 5.6e-10 38.9 0.0 1.1e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EPS28246.1 - 1.9e-06 27.3 0.0 3.1e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EPS28246.1 - 0.0064 16.7 0.0 0.015 15.5 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EPS28246.1 - 0.06 13.4 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate BCAS3 PF12490.3 EPS28247.1 - 0.097 11.9 0.1 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 PPR_2 PF13041.1 EPS28248.1 - 7.1e-10 38.7 0.7 0.003 17.5 0.0 6.5 5 2 1 6 6 6 3 PPR repeat family PPR_3 PF13812.1 EPS28248.1 - 5.4e-06 26.2 5.0 0.88 10.0 0.0 6.2 6 1 0 6 6 6 3 Pentatricopeptide repeat domain PPR PF01535.15 EPS28248.1 - 0.0018 18.1 8.1 1.3 9.1 0.1 5.7 6 0 0 6 6 6 1 PPR repeat LSM PF01423.17 EPS28249.1 - 9.9e-18 63.4 0.0 1.6e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EPS28249.1 - 0.0061 16.4 0.0 0.0087 15.9 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain Hat1_N PF10394.4 EPS28250.1 - 6.2e-44 149.8 0.0 1.2e-43 148.9 0.0 1.5 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Ank PF00023.25 EPS28251.1 - 0.05 13.4 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeat APH PF01636.18 EPS28252.1 - 4.8e-12 46.1 0.0 3.2e-11 43.4 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPS28252.1 - 0.042 13.4 0.0 0.06 12.9 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Cellulase PF00150.13 EPS28253.1 - 8.7e-19 67.7 1.3 1.2e-18 67.3 0.9 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CFEM PF05730.6 EPS28254.1 - 6.7e-08 32.2 11.3 1.2e-07 31.4 7.8 1.4 1 0 0 1 1 1 1 CFEM domain TIL PF01826.12 EPS28254.1 - 2.2 8.4 6.9 5.4 7.2 4.8 1.6 1 0 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain Zip PF02535.17 EPS28255.1 - 1.7e-41 142.2 9.3 2.6e-39 135.0 6.4 2.9 1 1 0 1 1 1 1 ZIP Zinc transporter DUF3649 PF12365.3 EPS28255.1 - 0.77 9.3 0.0 0.77 9.3 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3649) WD40 PF00400.27 EPS28256.1 - 4e-50 165.9 24.6 4.1e-09 35.9 0.2 7.8 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.2 EPS28256.1 - 2e-10 40.1 0.7 4.5e-10 39.0 0.5 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 EPS28256.1 - 1.7e-08 33.0 8.6 0.002 16.3 0.2 5.1 1 1 4 5 5 5 3 Nucleoporin Nup120/160 F-box PF00646.28 EPS28256.1 - 0.0013 18.3 1.0 0.0029 17.1 0.7 1.7 1 0 0 1 1 1 1 F-box domain Lamp PF01299.12 EPS28256.1 - 0.11 11.6 0.8 0.18 10.9 0.5 1.2 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Intg_mem_TP0381 PF09529.5 EPS28257.1 - 0.013 14.7 1.6 0.014 14.6 1.1 1.1 1 0 0 1 1 1 0 Integral membrane protein (intg_mem_TP0381) DUF872 PF05915.7 EPS28257.1 - 0.13 12.1 0.8 0.78 9.6 0.2 1.9 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Zn_clus PF00172.13 EPS28258.1 - 1.1e-07 31.6 8.7 2e-07 30.7 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_carr PF00153.22 EPS28259.1 - 3.3e-48 161.3 3.5 1e-16 60.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF155 PF02582.9 EPS28261.1 - 9.6e-54 181.9 0.1 1.4e-53 181.3 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 U3_snoRNA_assoc PF08297.6 EPS28262.1 - 6.1e-18 64.8 0.6 6.1e-18 64.8 0.4 3.7 3 1 0 3 3 3 2 U3 snoRNA associated CTK3 PF12243.3 EPS28263.1 - 1e-57 193.6 0.3 1.4e-57 193.2 0.2 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 EPS28263.1 - 5.7e-17 61.4 5.7 1.6e-16 60.0 4.0 1.8 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus HeLo PF14479.1 EPS28263.1 - 0.078 12.7 1.3 0.14 11.8 0.9 1.5 1 0 0 1 1 1 0 Prion-inhibition and propagation Voltage_CLC PF00654.15 EPS28264.1 - 1.2e-90 304.0 28.0 1.2e-90 304.0 19.4 1.4 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EPS28264.1 - 0.001 18.8 0.0 1.2 8.9 0.0 2.4 2 0 0 2 2 2 2 CBS domain AAA_5 PF07728.9 EPS28265.1 - 4.7e-130 428.1 1.0 4.2e-22 78.3 0.0 9.7 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EPS28265.1 - 7.1e-30 103.2 0.0 7.8e-11 41.7 0.0 7.4 7 0 0 7 7 7 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 EPS28265.1 - 1.7e-28 99.4 0.0 0.00014 22.0 0.0 7.1 6 0 0 6 6 6 6 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EPS28265.1 - 1.9e-24 86.1 0.0 0.00079 19.3 0.0 7.4 6 2 0 6 6 6 5 AAA domain AAA_17 PF13207.1 EPS28265.1 - 9.4e-22 78.0 1.0 0.0014 19.3 0.0 7.5 7 0 0 7 7 6 3 AAA domain AAA_14 PF13173.1 EPS28265.1 - 6e-21 74.6 0.0 0.00042 20.2 0.0 7.7 8 0 0 8 8 6 4 AAA domain AAA_16 PF13191.1 EPS28265.1 - 7.5e-21 74.9 9.5 0.0018 18.2 0.1 8.7 7 0 0 7 7 7 4 AAA ATPase domain AAA_22 PF13401.1 EPS28265.1 - 1.4e-20 73.8 0.5 0.015 15.4 0.0 8.5 7 0 0 7 7 7 4 AAA domain ABC_tran PF00005.22 EPS28265.1 - 1.2e-18 67.7 0.3 0.0021 18.3 0.0 7.0 6 0 0 6 6 6 3 ABC transporter AAA_18 PF13238.1 EPS28265.1 - 1.5e-18 67.3 2.1 0.021 15.1 0.0 7.5 7 0 0 7 7 6 4 AAA domain Zeta_toxin PF06414.7 EPS28265.1 - 6.5e-17 61.2 0.9 0.065 12.3 0.0 7.6 8 0 0 8 8 7 4 Zeta toxin Sigma54_activat PF00158.21 EPS28265.1 - 3.2e-15 55.9 0.0 0.016 14.7 0.0 6.1 6 0 0 6 6 5 3 Sigma-54 interaction domain UPF0079 PF02367.12 EPS28265.1 - 6.1e-14 51.7 6.0 0.073 12.7 0.0 6.9 7 0 0 7 7 6 3 Uncharacterised P-loop hydrolase UPF0079 Mg_chelatase PF01078.16 EPS28265.1 - 1.6e-13 50.2 1.3 1.3 8.1 0.0 9.1 9 1 0 9 9 9 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EPS28265.1 - 4.5e-13 49.3 1.1 0.73 10.0 0.0 6.8 7 0 0 7 7 6 4 RNA helicase Arch_ATPase PF01637.13 EPS28265.1 - 4.7e-13 49.3 0.1 0.96 9.0 0.0 6.5 6 0 0 6 6 6 3 Archaeal ATPase DUF258 PF03193.11 EPS28265.1 - 2.5e-12 46.2 2.4 0.12 11.5 0.1 6.2 6 0 0 6 6 6 3 Protein of unknown function, DUF258 Miro PF08477.8 EPS28265.1 - 3.7e-12 46.8 2.0 0.32 11.5 0.1 6.9 6 0 0 6 6 6 1 Miro-like protein Sigma54_activ_2 PF14532.1 EPS28265.1 - 5.4e-12 45.9 0.3 0.035 14.1 0.0 6.2 5 0 0 5 5 5 2 Sigma-54 interaction domain NACHT PF05729.7 EPS28265.1 - 6.1e-12 45.5 6.7 0.088 12.4 0.1 5.5 5 0 0 5 5 5 4 NACHT domain MobB PF03205.9 EPS28265.1 - 1.1e-11 44.5 1.6 0.49 10.0 0.1 6.7 6 0 0 6 6 6 2 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 EPS28265.1 - 3.6e-11 42.4 3.5 0.56 9.0 0.0 6.4 6 0 0 6 6 6 3 Type II/IV secretion system protein SRP54 PF00448.17 EPS28265.1 - 4e-11 42.7 5.9 0.026 13.9 0.0 5.9 6 0 0 6 6 5 2 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EPS28265.1 - 1.9e-10 40.4 3.8 0.92 8.8 0.0 5.9 5 0 0 5 5 5 2 AAA domain PduV-EutP PF10662.4 EPS28265.1 - 2.5e-10 40.0 5.2 0.081 12.4 0.0 6.2 6 0 0 6 6 6 3 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 EPS28265.1 - 2.7e-10 40.4 6.3 0.19 11.7 0.1 6.7 6 0 0 6 6 6 2 AAA domain MMR_HSR1 PF01926.18 EPS28265.1 - 3.2e-10 39.9 0.5 0.012 15.5 0.0 6.8 7 0 0 7 7 6 1 50S ribosome-binding GTPase AAA_19 PF13245.1 EPS28265.1 - 4.4e-10 39.1 7.1 0.58 9.9 0.0 7.2 7 0 0 7 7 7 3 Part of AAA domain RuvB_N PF05496.7 EPS28265.1 - 1.2e-09 37.6 6.5 0.37 9.7 0.0 7.3 7 1 1 8 8 8 3 Holliday junction DNA helicase ruvB N-terminus AAA_29 PF13555.1 EPS28265.1 - 5.3e-09 35.4 2.1 0.27 10.8 0.0 6.3 6 0 0 6 6 6 1 P-loop containing region of AAA domain DUF815 PF05673.8 EPS28265.1 - 1.4e-08 33.9 2.1 0.43 9.4 0.0 5.9 6 0 0 6 6 6 3 Protein of unknown function (DUF815) IstB_IS21 PF01695.12 EPS28265.1 - 8e-07 28.6 0.1 2.4 7.5 0.0 5.2 5 0 0 5 5 5 2 IstB-like ATP binding protein Rad17 PF03215.10 EPS28265.1 - 8.1e-07 28.0 0.6 0.053 12.2 0.0 4.7 5 0 0 5 5 5 1 Rad17 cell cycle checkpoint protein Bac_DnaA PF00308.13 EPS28265.1 - 1.6e-06 27.9 0.0 0.94 9.0 0.0 3.9 4 0 0 4 4 3 2 Bacterial dnaA protein NTPase_1 PF03266.10 EPS28265.1 - 1.7e-06 27.8 7.7 1.5 8.5 0.1 5.7 5 0 0 5 5 5 2 NTPase AAA_7 PF12775.2 EPS28265.1 - 3.5e-06 26.3 0.5 0.52 9.3 0.0 4.9 5 0 0 5 5 5 1 P-loop containing dynein motor region D3 Viral_helicase1 PF01443.13 EPS28265.1 - 3.8e-06 26.6 0.2 0.34 10.3 0.0 5.0 5 0 0 5 5 4 1 Viral (Superfamily 1) RNA helicase ATP_bind_1 PF03029.12 EPS28265.1 - 4.2e-06 26.4 3.5 2.4 7.6 0.0 5.6 5 0 0 5 5 4 1 Conserved hypothetical ATP binding protein cobW PF02492.14 EPS28265.1 - 5.6e-06 25.9 4.9 3 7.2 0.0 6.1 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.5 EPS28265.1 - 7.3e-06 25.3 5.0 2.3 7.4 0.0 6.0 6 0 0 6 6 6 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.1 EPS28265.1 - 1.3e-05 24.8 1.2 4 6.9 0.0 5.6 6 0 0 6 6 6 0 AAA domain NB-ARC PF00931.17 EPS28265.1 - 8.2e-05 21.6 2.2 2.3 7.0 0.0 4.9 5 0 0 5 5 4 1 NB-ARC domain TIP49 PF06068.8 EPS28265.1 - 0.00037 19.3 3.9 0.43 9.2 0.0 4.6 5 0 0 5 5 5 1 TIP49 C-terminus ResIII PF04851.10 EPS28265.1 - 0.00037 20.3 7.1 0.16 11.8 0.0 5.0 6 0 0 6 6 4 1 Type III restriction enzyme, res subunit MCM PF00493.18 EPS28265.1 - 0.00048 19.0 0.4 2.3 6.9 0.0 4.5 5 0 0 5 5 5 1 MCM2/3/5 family PhoH PF02562.11 EPS28265.1 - 0.00059 19.1 0.6 2.6 7.2 0.0 4.3 4 0 0 4 4 4 0 PhoH-like protein ATP-synt_ab PF00006.20 EPS28265.1 - 0.0014 18.1 0.1 11 5.3 0.0 4.5 5 0 0 5 5 5 0 ATP synthase alpha/beta family, nucleotide-binding domain KaiC PF06745.8 EPS28265.1 - 0.0016 17.6 0.3 24 3.9 0.0 4.8 5 0 0 5 5 4 0 KaiC FeoB_N PF02421.13 EPS28265.1 - 0.0017 17.6 6.4 0.25 10.6 0.0 5.2 6 0 0 6 6 5 1 Ferrous iron transport protein B KTI12 PF08433.5 EPS28265.1 - 0.0031 16.7 0.6 10 5.2 0.0 4.8 6 0 0 6 6 4 0 Chromatin associated protein KTI12 AAA_15 PF13175.1 EPS28265.1 - 0.012 14.6 0.2 11 4.9 0.0 4.2 5 0 0 5 5 5 0 AAA ATPase domain CbiA PF01656.18 EPS28265.1 - 0.015 14.6 0.3 0.86 8.9 0.1 3.2 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain Gtr1_RagA PF04670.7 EPS28265.1 - 0.021 13.9 0.4 23 4.0 0.0 4.4 5 0 0 5 5 5 0 Gtr1/RagA G protein conserved region ArgK PF03308.11 EPS28265.1 - 0.022 13.5 3.5 2 7.1 0.1 3.5 4 0 0 4 4 3 0 ArgK protein Septin PF00735.13 EPS28265.1 - 0.058 12.4 1.9 6 5.7 0.0 4.0 5 0 0 5 5 4 0 Septin AAA_6 PF12774.2 EPS28265.1 - 0.078 12.5 0.0 1.2e+02 2.0 0.0 5.2 7 0 0 7 7 5 0 Hydrolytic ATP binding site of dynein motor region D1 Dynamin_N PF00350.18 EPS28265.1 - 0.087 12.6 2.5 26 4.5 0.0 4.3 4 0 0 4 4 3 0 Dynamin family Y_phosphatase PF00102.22 EPS28265.1 - 0.83 8.9 2.5 14 4.8 0.0 3.7 5 0 0 5 5 5 0 Protein-tyrosine phosphatase PRCC PF10253.4 EPS28266.1 - 5.9e-44 150.9 3.9 5.9e-44 150.9 2.7 3.2 3 1 0 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting Pkinase PF00069.20 EPS28267.1 - 1.7e-67 227.3 0.0 2.5e-67 226.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS28267.1 - 9.1e-37 126.5 0.0 1.5e-36 125.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPS28267.1 - 3.3e-06 26.2 0.0 6.4e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EPS28267.1 - 0.016 14.9 1.0 0.053 13.2 0.2 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family DUF605 PF04652.11 EPS28267.1 - 1.3 8.3 17.7 1.7 7.9 12.3 1.1 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 EPS28267.1 - 2.7 7.8 24.5 3.7 7.3 17.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-Tim10_DDP PF02953.10 EPS28268.1 - 1e-22 79.1 0.9 1.3e-22 78.8 0.6 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Condensin2nSMC PF12422.3 EPS28268.1 - 0.038 13.7 0.1 0.042 13.5 0.1 1.1 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit DUF3398 PF11878.3 EPS28268.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3398) Lectin_leg-like PF03388.8 EPS28269.1 - 1.3e-65 220.7 0.0 1.7e-65 220.3 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family ATG27 PF09451.5 EPS28269.1 - 0.006 15.8 0.1 0.0075 15.5 0.0 1.1 1 0 0 1 1 1 1 Autophagy-related protein 27 TMEM237 PF15383.1 EPS28270.1 - 0.24 10.4 1.0 0.4 9.7 0.7 1.3 1 0 0 1 1 1 0 Transmembrane protein 237 BRF1 PF07741.8 EPS28270.1 - 0.75 10.0 29.6 0.066 13.4 6.4 4.0 2 2 1 3 3 3 0 Brf1-like TBP-binding domain SIN1 PF05422.7 EPS28271.1 - 1.7e-28 99.4 8.1 3.6e-16 58.7 5.5 3.2 2 1 0 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) TUG-UBL1 PF11470.3 EPS28271.1 - 0.08 12.8 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 GLUT4 regulating protein TUG Glyco_hydro_28 PF00295.12 EPS28272.1 - 1.9e-108 362.3 19.5 2.2e-108 362.0 13.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 RFC1 PF08519.7 EPS28274.1 - 2.3e-58 196.3 0.1 4.8e-58 195.3 0.0 1.6 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 EPS28274.1 - 5.4e-13 48.9 0.0 2e-12 47.0 0.0 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 EPS28274.1 - 1.4e-09 38.2 0.1 4.3e-09 36.6 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPS28274.1 - 8.3e-06 25.9 0.0 2.3e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EPS28274.1 - 7.7e-05 21.5 0.0 0.00049 18.9 0.0 2.0 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EPS28274.1 - 0.00016 22.5 0.0 0.00016 22.5 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 EPS28274.1 - 0.001 18.9 0.0 0.0032 17.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPS28274.1 - 0.0013 18.3 0.1 0.0044 16.7 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EPS28274.1 - 0.0017 18.3 0.6 0.0078 16.2 0.0 2.4 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 EPS28274.1 - 0.002 17.2 0.0 0.0038 16.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EPS28274.1 - 0.008 16.0 0.0 0.029 14.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPS28274.1 - 0.014 15.6 0.1 0.014 15.6 0.0 3.7 4 0 0 4 4 4 0 AAA domain NTPase_1 PF03266.10 EPS28274.1 - 0.047 13.3 0.3 0.65 9.6 0.0 2.4 1 1 1 2 2 2 0 NTPase AAA_28 PF13521.1 EPS28274.1 - 0.081 12.8 0.0 0.081 12.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain PTCB-BRCT PF12738.2 EPS28274.1 - 0.096 12.5 0.0 0.3 10.9 0.0 1.9 1 0 0 1 1 1 0 twin BRCT domain Ribosomal_L16 PF00252.13 EPS28275.1 - 1.5e-28 99.2 0.1 1.9e-28 98.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Rep_fac_C PF08542.6 EPS28276.1 - 5.1e-21 74.4 0.0 1.2e-20 73.2 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EPS28276.1 - 1.3e-11 44.4 0.0 2.7e-11 43.3 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EPS28276.1 - 2.6e-06 27.6 0.1 5.8e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPS28276.1 - 0.00014 22.0 0.6 0.00059 19.9 0.3 2.2 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EPS28276.1 - 0.0012 18.8 1.7 0.082 12.8 0.0 2.9 2 1 0 3 3 3 1 AAA ATPase domain Sigma54_activ_2 PF14532.1 EPS28276.1 - 0.018 15.0 0.2 0.31 11.0 0.1 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 EPS28276.1 - 0.026 14.8 0.0 0.051 13.8 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_33 PF13671.1 EPS28276.1 - 0.027 14.3 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EPS28276.1 - 0.027 13.9 0.1 0.84 9.0 0.0 2.3 1 1 0 2 2 2 0 AAA-like domain Arch_ATPase PF01637.13 EPS28276.1 - 0.071 12.7 0.0 0.14 11.8 0.0 1.4 1 1 0 1 1 1 0 Archaeal ATPase SNF2_N PF00176.18 EPS28276.1 - 0.077 11.7 0.1 0.095 11.4 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain T4SS-DNA_transf PF02534.9 EPS28276.1 - 0.1 11.1 0.0 0.16 10.4 0.0 1.2 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer Rad17 PF03215.10 EPS28276.1 - 0.12 11.0 0.0 0.21 10.2 0.0 1.4 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein CtaG_Cox11 PF04442.9 EPS28277.1 - 2.6e-58 196.1 0.0 4.4e-58 195.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Cation_ATPase_C PF00689.16 EPS28278.1 - 0.024 14.1 0.0 0.047 13.2 0.0 1.5 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus HLH PF00010.21 EPS28279.1 - 7.8e-08 31.9 0.0 1.4e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain KIAA1328 PF15369.1 EPS28279.1 - 0.24 11.1 4.5 0.39 10.4 3.1 1.2 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 CENP-Q PF13094.1 EPS28280.1 - 7.9e-42 143.0 6.6 7.9e-42 143.0 4.6 1.8 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit CCDC-167 PF15188.1 EPS28280.1 - 0.5 10.3 7.9 1.6 8.6 4.5 2.3 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 DUF4337 PF14235.1 EPS28280.1 - 0.99 9.2 6.0 2.4 7.9 4.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Macoilin PF09726.4 EPS28280.1 - 1.1 7.3 9.9 1.6 6.9 6.8 1.2 1 0 0 1 1 1 0 Transmembrane protein Atg14 PF10186.4 EPS28280.1 - 2.3 7.0 11.8 0.42 9.5 5.5 1.6 2 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 COG2 PF06148.6 EPS28280.1 - 5.9 6.7 9.1 2.3 8.1 3.0 2.5 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4207 PF13904.1 EPS28281.1 - 0.8 9.0 4.0 0.18 11.1 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4207) SPO22 PF08631.5 EPS28282.1 - 3.5e-07 29.5 0.0 2.1e-06 27.0 0.0 2.2 2 0 0 2 2 2 1 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.1 EPS28282.1 - 2.7e-05 24.0 6.9 0.02 14.8 1.3 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF506 PF04720.7 EPS28282.1 - 0.085 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Glyco_transf_7C PF02709.9 EPS28282.1 - 0.12 11.9 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase TPR_2 PF07719.12 EPS28282.1 - 2.1 8.4 10.7 0.61 10.1 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat WD40 PF00400.27 EPS28284.1 - 1.5e-21 75.4 15.9 4.3e-06 26.4 0.0 9.8 10 0 0 10 10 10 4 WD domain, G-beta repeat SGL PF08450.7 EPS28284.1 - 0.13 11.6 0.0 0.27 10.5 0.0 1.5 1 0 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region Neugrin PF06413.6 EPS28285.1 - 9.6e-14 51.7 0.5 1.7e-13 50.9 0.3 1.4 1 0 0 1 1 1 1 Neugrin MRP-L20 PF12824.2 EPS28285.1 - 5.3e-06 26.5 9.3 1.8e-05 24.8 6.4 1.8 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_11 PF08279.7 EPS28285.1 - 0.13 11.8 0.0 0.23 11.1 0.0 1.3 1 0 0 1 1 1 0 HTH domain Rgp1 PF08737.5 EPS28286.1 - 9.5e-113 377.3 0.0 1.5e-112 376.7 0.0 1.3 1 0 0 1 1 1 1 Rgp1 Arrestin_N PF00339.24 EPS28286.1 - 0.00051 19.8 0.7 0.00098 18.9 0.0 1.8 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EPS28286.1 - 0.065 13.3 0.0 0.34 11.0 0.0 2.2 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Spo0M PF07070.6 EPS28286.1 - 0.19 11.0 0.0 0.44 9.8 0.0 1.5 1 0 0 1 1 1 0 SpoOM protein Mob1_phocein PF03637.12 EPS28287.1 - 2.8e-71 238.7 0.0 3.4e-71 238.4 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family OSCP PF00213.13 EPS28288.1 - 2.9e-44 150.9 2.1 3.3e-44 150.7 1.5 1.0 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Gasdermin PF04598.7 EPS28288.1 - 0.045 12.5 0.2 0.05 12.3 0.2 1.2 1 0 0 1 1 1 0 Gasdermin family DUF1539 PF07560.6 EPS28288.1 - 0.05 13.4 0.3 6.1 6.7 0.0 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) DUF148 PF02520.12 EPS28288.1 - 0.058 13.1 0.6 1.1 9.0 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function DUF148 Glyco_hydro_63 PF03200.11 EPS28289.1 - 1.9e-06 26.0 3.5 0.00014 19.8 0.2 3.4 2 1 0 2 2 2 2 Mannosyl oligosaccharide glucosidase ADIP PF11559.3 EPS28290.1 - 0.00069 19.5 1.1 0.00085 19.2 0.8 1.1 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding SlyX PF04102.7 EPS28290.1 - 0.017 15.5 1.8 0.026 14.8 1.3 1.3 1 0 0 1 1 1 0 SlyX Mod_r PF07200.8 EPS28290.1 - 0.021 14.7 0.8 0.023 14.5 0.6 1.1 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein DivIC PF04977.10 EPS28290.1 - 0.064 12.7 2.1 0.088 12.3 1.5 1.2 1 0 0 1 1 1 0 Septum formation initiator RIC3 PF15361.1 EPS28290.1 - 0.79 9.9 3.6 0.79 9.9 1.8 1.6 1 1 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Bromodomain PF00439.20 EPS28291.1 - 1.7e-17 63.1 0.0 5.3e-17 61.5 0.0 1.8 2 0 0 2 2 2 1 Bromodomain Diphthamide_syn PF01866.12 EPS28292.1 - 5.1e-114 380.6 0.0 1.7e-113 378.9 0.0 1.7 2 0 0 2 2 2 1 Putative diphthamide synthesis protein HMGL-like PF00682.14 EPS28293.1 - 1.9e-40 138.9 0.1 4.5e-40 137.7 0.1 1.6 1 1 0 1 1 1 1 HMGL-like DUF1674 PF07896.7 EPS28294.1 - 6e-17 61.5 4.2 1.4e-16 60.4 2.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) Aminotran_3 PF00202.16 EPS28295.1 - 8.7e-97 323.9 0.0 1.1e-96 323.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EPS28295.1 - 1.8e-05 23.8 0.0 2.7e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II CLN3 PF02487.12 EPS28296.1 - 1.7e-95 320.1 20.5 6.9e-93 311.5 14.2 2.8 1 1 0 1 1 1 1 CLN3 protein Abhydrolase_3 PF07859.8 EPS28297.1 - 1.3e-36 126.1 0.5 1.9e-23 83.1 0.0 3.1 3 1 1 4 4 4 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EPS28297.1 - 0.031 12.9 0.0 0.051 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) RAP1 PF07218.6 EPS28297.1 - 0.4 8.7 1.9 0.57 8.2 1.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MFS_1 PF07690.11 EPS28298.1 - 1.2e-31 109.7 19.6 1.2e-31 109.7 13.6 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS28298.1 - 8.2e-10 37.8 9.1 8.2e-10 37.8 6.3 3.4 3 1 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 EPS28298.1 - 0.00097 17.4 3.2 0.0018 16.5 2.2 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Rxt3 PF08642.5 EPS28299.1 - 2.5e-28 98.6 0.0 5.1e-28 97.6 0.0 1.6 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 EPS28299.1 - 0.004 17.0 0.0 0.0099 15.8 0.0 1.6 1 0 0 1 1 1 1 LCCL domain SLEI_Leptospira PF07620.6 EPS28299.1 - 0.13 12.0 0.1 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 SLEI Carn_acyltransf PF00755.15 EPS28300.1 - 2.5e-183 610.3 0.0 2.9e-183 610.1 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF2968 PF11180.3 EPS28301.1 - 0.032 13.6 0.3 0.032 13.6 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) DivIC PF04977.10 EPS28301.1 - 0.042 13.3 0.5 0.042 13.3 0.4 2.3 2 0 0 2 2 2 0 Septum formation initiator DASH_Spc34 PF08657.5 EPS28301.1 - 0.1 12.2 4.9 1 8.9 1.8 2.2 2 0 0 2 2 2 0 DASH complex subunit Spc34 TMCO5 PF14992.1 EPS28301.1 - 0.14 11.3 2.2 0.32 10.0 0.1 1.9 2 0 0 2 2 2 0 TMCO5 family DUF2046 PF09755.4 EPS28301.1 - 0.15 10.8 9.0 0.028 13.3 3.3 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) DUF3573 PF12097.3 EPS28301.1 - 0.2 10.2 0.6 2.5 6.6 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3573) FlxA PF14282.1 EPS28301.1 - 0.32 10.9 16.3 9.2 6.2 8.6 2.7 2 0 0 2 2 2 0 FlxA-like protein DUF3138 PF11336.3 EPS28301.1 - 0.98 7.5 11.4 1.6 6.8 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) MerR-DNA-bind PF09278.6 EPS28301.1 - 1.1 9.7 12.1 0.11 12.9 0.6 2.3 2 0 0 2 2 2 0 MerR, DNA binding Nsp1_C PF05064.8 EPS28301.1 - 1.8 8.2 8.1 1.1 8.8 2.8 2.1 2 0 0 2 2 2 0 Nsp1-like C-terminal region IncA PF04156.9 EPS28301.1 - 2.9 7.4 12.0 5.4 6.5 0.1 2.2 2 0 0 2 2 2 0 IncA protein Spc24 PF08286.6 EPS28301.1 - 2.9 7.6 6.2 11 5.6 0.1 2.2 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF2051 PF09738.4 EPS28301.1 - 3.3 6.9 9.3 0.59 9.3 0.7 2.7 2 1 1 3 3 3 0 Double stranded RNA binding protein (DUF2051) SPX PF03105.14 EPS28301.1 - 7.8 6.1 10.9 0.16 11.7 3.0 1.4 2 0 0 2 2 1 0 SPX domain MFS_1 PF07690.11 EPS28302.1 - 4.9e-25 87.9 28.9 2.3e-24 85.7 17.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pterin_4a PF01329.14 EPS28303.1 - 1.9e-24 85.2 0.1 2.5e-24 84.8 0.1 1.2 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Sec62 PF03839.11 EPS28305.1 - 1.3e-55 188.2 0.6 2.3e-55 187.4 0.4 1.3 1 0 0 1 1 1 1 Translocation protein Sec62 VIT1 PF01988.14 EPS28305.1 - 0.19 11.2 1.3 0.43 10.0 0.9 1.8 1 1 0 1 1 1 0 VIT family Med15 PF09606.5 EPS28305.1 - 1.6 6.7 44.4 1.9 6.5 30.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.8 EPS28305.1 - 8.3 6.1 28.1 26 4.5 0.0 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Lectin_C PF00059.16 EPS28306.1 - 0.041 14.5 0.0 0.11 13.1 0.0 1.7 1 0 0 1 1 1 0 Lectin C-type domain Pyr_redox_2 PF07992.9 EPS28308.1 - 1.5e-07 31.5 0.0 2.9e-06 27.2 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPS28308.1 - 2.1e-05 24.6 0.0 0.068 13.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPS28308.1 - 0.00091 19.2 0.0 0.0021 18.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EPS28308.1 - 0.013 14.0 0.0 0.022 13.2 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.1 EPS28308.1 - 0.014 15.2 0.0 0.041 13.6 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding K_oxygenase PF13434.1 EPS28308.1 - 0.14 11.0 0.0 0.56 9.0 0.0 1.8 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Cerato-platanin PF07249.7 EPS28309.1 - 1.3e-36 125.2 0.3 2.9e-36 124.0 0.1 1.6 1 1 1 2 2 2 1 Cerato-platanin Barwin PF00967.12 EPS28309.1 - 0.0073 15.9 0.1 0.0097 15.5 0.1 1.3 1 1 0 1 1 1 1 Barwin family Glyco_hydro_45 PF02015.11 EPS28309.1 - 0.034 14.2 0.0 0.038 14.0 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 45 PsbY PF06298.6 EPS28309.1 - 0.076 12.5 0.1 8.9 5.9 0.0 2.4 2 0 0 2 2 2 0 Photosystem II protein Y (PsbY) Git3 PF11710.3 EPS28311.1 - 2.1e-22 79.6 9.8 2.1e-22 79.6 6.8 1.9 2 1 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EPS28311.1 - 1e-10 41.2 0.5 9.6e-10 38.0 0.0 2.5 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Nterm_IS4 PF13006.2 EPS28311.1 - 0.058 13.4 0.1 0.18 11.8 0.1 1.9 1 0 0 1 1 1 0 Insertion element 4 transposase N-terminal Cytochrom_B561 PF03188.11 EPS28312.1 - 2.1e-08 34.0 11.8 4.7e-08 32.9 8.2 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 EPS28312.1 - 4e-05 23.1 1.5 0.00011 21.7 1.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) Ferric_reduct PF01794.14 EPS28312.1 - 0.016 15.2 5.9 0.033 14.2 1.5 2.6 2 1 0 2 2 2 0 Ferric reductase like transmembrane component Abhydrolase_3 PF07859.8 EPS28313.1 - 7.5e-44 149.8 0.0 1.8e-35 122.4 0.0 3.8 4 0 0 4 4 4 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EPS28313.1 - 3.5e-18 65.4 0.0 5.8e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EPS28313.1 - 0.00012 21.8 0.0 0.00027 20.7 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPS28313.1 - 0.00022 21.2 0.0 0.00052 19.9 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EPS28313.1 - 0.055 12.1 0.0 1.1 7.9 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family ParA PF10609.4 EPS28314.1 - 5.2e-33 112.7 0.1 1e-32 111.8 0.1 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EPS28314.1 - 1.4e-16 60.4 0.0 2.1e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EPS28314.1 - 6.8e-09 35.8 0.0 1.9e-08 34.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 EPS28314.1 - 1.3e-05 24.3 0.1 2.2e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 EPS28314.1 - 0.0015 17.6 1.0 0.0063 15.5 0.4 2.1 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_25 PF13481.1 EPS28314.1 - 0.0068 15.8 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 EPS28314.1 - 0.016 14.4 0.0 0.2 10.7 0.0 2.0 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family Ribosomal_S27e PF01667.12 EPS28314.1 - 0.069 12.7 0.2 0.14 11.6 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein S27 DUF1610 PF07754.6 EPS28314.1 - 0.32 11.1 1.7 1.1 9.4 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) TRAUB PF08164.7 EPS28315.1 - 3e-32 110.5 0.6 1.8e-31 108.0 0.0 2.7 3 0 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 EPS28315.1 - 4e-32 111.1 1.5 4e-32 111.1 1.1 2.8 3 0 0 3 3 3 1 Apoptosis antagonizing transcription factor Nop14 PF04147.7 EPS28315.1 - 0.0036 15.3 28.8 0.0065 14.4 20.0 1.5 1 0 0 1 1 1 1 Nop14-like family Daxx PF03344.10 EPS28315.1 - 0.93 7.8 31.7 1.5 7.2 21.5 1.7 1 1 0 1 1 1 0 Daxx Family Tom37_C PF11801.3 EPS28315.1 - 1.7 8.5 7.0 1.2 8.9 3.2 2.0 1 1 0 1 1 1 0 Tom37 C-terminal domain DUF1793 PF08760.6 EPS28316.1 - 4.3e-49 166.6 0.0 7.5e-49 165.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) GBA2_N PF12215.3 EPS28316.1 - 2.2e-05 23.7 0.2 0.00011 21.4 0.1 2.1 2 1 0 2 2 2 1 beta-Glucocerebrosidase 2 N terminal DUF2433 PF10360.4 EPS28317.1 - 1.4e-51 174.2 0.0 2.2e-51 173.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos_2 PF12850.2 EPS28317.1 - 0.002 17.9 0.0 0.0051 16.6 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EPS28317.1 - 0.0054 16.1 0.0 0.011 15.1 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PAP1 PF08601.5 EPS28318.1 - 1.1e-87 294.9 11.4 1.1e-87 294.9 7.9 2.9 2 1 0 2 2 2 2 Transcription factor PAP1 bZIP_1 PF00170.16 EPS28318.1 - 5.8e-09 35.7 9.8 1.2e-08 34.8 6.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor ERM PF00769.14 EPS28318.1 - 0.0011 18.5 5.0 0.0024 17.4 3.5 1.5 1 0 0 1 1 1 1 Ezrin/radixin/moesin family bZIP_Maf PF03131.12 EPS28318.1 - 0.012 15.9 10.7 0.031 14.5 7.4 1.7 1 0 0 1 1 1 0 bZIP Maf transcription factor SlyX PF04102.7 EPS28318.1 - 0.039 14.3 0.8 0.1 12.9 0.6 1.8 1 0 0 1 1 1 0 SlyX MbeD_MobD PF04899.7 EPS28318.1 - 0.075 12.9 1.9 0.18 11.7 1.3 1.6 1 0 0 1 1 1 0 MbeD/MobD like bZIP_2 PF07716.10 EPS28318.1 - 0.078 12.8 14.7 0.45 10.3 10.2 2.2 1 1 0 1 1 1 0 Basic region leucine zipper DUF904 PF06005.7 EPS28318.1 - 0.093 13.0 4.5 0.28 11.5 3.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Sirohm_synth_M PF14824.1 EPS28318.1 - 0.16 10.9 1.0 8.8 5.4 0.2 2.6 2 0 0 2 2 2 0 Sirohaem biosynthesis protein central FlaC_arch PF05377.6 EPS28318.1 - 0.18 11.7 0.7 0.35 10.8 0.5 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) IncA PF04156.9 EPS28318.1 - 0.92 9.0 5.6 2.2 7.8 3.9 1.6 1 0 0 1 1 1 0 IncA protein EMP24_GP25L PF01105.19 EPS28318.1 - 1 9.0 2.9 0.76 9.4 0.9 1.5 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Macoilin PF09726.4 EPS28318.1 - 1.3 7.2 14.4 0.46 8.7 1.4 2.2 2 0 0 2 2 2 0 Transmembrane protein Adeno_PIX PF03955.9 EPS28318.1 - 1.8 9.0 7.2 0.15 12.5 0.6 2.2 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) TUDOR PF00567.19 EPS28319.1 - 0.0034 17.1 0.0 0.042 13.6 0.0 2.1 2 0 0 2 2 2 1 Tudor domain DUF4537 PF15057.1 EPS28319.1 - 0.004 16.9 0.0 0.0077 16.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) Fis1_TPR_C PF14853.1 EPS28319.1 - 0.021 14.6 0.3 0.037 13.9 0.2 1.4 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat Rad9_Rad53_bind PF08605.5 EPS28319.1 - 0.085 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Fungal Rad9-like Rad53-binding DUF2730 PF10805.3 EPS28319.1 - 0.093 12.4 1.2 0.15 11.8 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF1325 PF07039.6 EPS28319.1 - 0.11 12.1 0.2 0.58 9.7 0.0 2.0 2 0 0 2 2 2 0 SGF29 tudor-like domain DUF3275 PF11679.3 EPS28319.1 - 5.7 6.4 8.9 5.6 6.5 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) Patched PF02460.13 EPS28320.1 - 5.8e-79 265.9 11.0 3.9e-78 263.2 7.7 1.9 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 EPS28320.1 - 4.8e-50 168.9 6.9 4.8e-50 168.9 4.8 3.0 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 EPS28320.1 - 9.5e-06 24.5 11.2 9.5e-06 24.5 7.8 3.7 3 1 0 3 3 3 1 MMPL family DUF3278 PF11683.3 EPS28320.1 - 3.4 7.6 8.0 13 5.7 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3278) HEAT_2 PF13646.1 EPS28321.1 - 2e-22 79.2 7.5 3.9e-06 27.0 0.0 8.1 6 3 2 8 8 8 6 HEAT repeats HEAT PF02985.17 EPS28321.1 - 1.7e-21 74.3 6.2 5.2e-05 22.9 0.1 11.1 11 1 1 12 12 12 3 HEAT repeat HEAT_EZ PF13513.1 EPS28321.1 - 1.1e-20 73.4 6.7 1.2e-05 25.6 0.0 10.4 11 1 0 11 11 11 4 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EPS28321.1 - 3.7e-13 49.6 0.4 0.18 12.1 0.0 6.6 6 1 1 7 7 6 3 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 EPS28321.1 - 4.8e-11 42.4 0.3 3.2e-09 36.5 0.0 3.4 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cnd1 PF12717.2 EPS28321.1 - 1.3e-10 41.4 2.5 0.0029 17.4 0.0 3.9 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 EPS28321.1 - 1.2e-07 31.3 0.0 0.00077 18.8 0.0 4.2 4 2 0 4 4 4 2 CLASP N terminal MMS19_C PF12460.3 EPS28321.1 - 1e-05 24.4 1.7 0.0019 16.9 0.0 4.0 4 0 0 4 4 4 1 RNAPII transcription regulator C-terminal UME PF08064.8 EPS28321.1 - 5.4e-05 23.1 0.0 1.1 9.2 0.0 5.3 4 3 1 5 5 5 1 UME (NUC010) domain Arm PF00514.18 EPS28321.1 - 0.00062 19.4 0.7 4.2 7.3 0.0 5.8 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 EPS28321.1 - 0.001 17.5 0.7 0.33 9.2 0.0 3.7 3 0 0 3 3 3 1 Adaptin N terminal region ParcG PF10274.4 EPS28321.1 - 0.0018 18.2 0.8 0.045 13.6 0.2 3.1 3 0 0 3 3 3 1 Parkin co-regulated protein DUF4042 PF13251.1 EPS28321.1 - 0.063 12.7 1.1 0.45 9.9 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4042) ERO1 PF04137.10 EPS28321.1 - 0.11 11.4 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Zn_clus PF00172.13 EPS28322.1 - 7e-09 35.4 12.8 1.4e-08 34.4 8.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EPS28322.1 - 1.9e-08 33.5 2.0 2.7e-08 32.9 0.1 2.4 2 1 0 2 2 2 1 Fungal specific transcription factor domain Med7 PF05983.6 EPS28323.1 - 7.4e-58 194.9 2.1 9.2e-58 194.5 1.4 1.1 1 0 0 1 1 1 1 MED7 protein PAP2 PF01569.16 EPS28324.1 - 5.3e-23 81.1 1.1 5.3e-23 81.1 0.8 2.1 1 1 1 2 2 2 1 PAP2 superfamily DUF2933 PF11666.3 EPS28324.1 - 0.37 10.3 0.1 0.37 10.3 0.1 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2933) Fungal_trans_2 PF11951.3 EPS28325.1 - 1.5e-73 247.6 3.3 1.8e-73 247.3 2.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS28325.1 - 1.3e-07 31.4 8.5 2.5e-07 30.4 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2740 PF10872.3 EPS28325.1 - 0.15 11.7 0.0 0.37 10.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) F-actin_cap_A PF01267.12 EPS28327.1 - 4.5e-94 314.4 0.0 5.1e-94 314.3 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Endonuc-MspI PF09208.5 EPS28327.1 - 0.078 12.0 0.2 3.3 6.7 0.0 2.1 2 0 0 2 2 2 0 Restriction endonuclease MspI PEX11 PF05648.9 EPS28328.1 - 2.3e-37 128.4 0.0 2.7e-37 128.2 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) HET PF06985.6 EPS28329.1 - 0.00027 21.1 0.1 0.0089 16.1 0.1 2.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SET PF00856.23 EPS28334.1 - 0.0024 18.1 0.0 0.0041 17.4 0.0 1.3 1 0 0 1 1 1 1 SET domain 2-Hacid_dh_C PF02826.14 EPS28336.1 - 1.9e-46 157.4 0.0 3.3e-46 156.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EPS28336.1 - 5.2e-09 35.6 0.0 6.7e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EPS28336.1 - 0.013 15.3 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Drf_DAD PF06345.6 EPS28336.1 - 0.089 12.6 0.3 0.21 11.4 0.2 1.6 1 0 0 1 1 1 0 DRF Autoregulatory Domain Acetyltransf_7 PF13508.1 EPS28337.1 - 5.4e-09 36.0 0.0 2.8e-08 33.7 0.0 2.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPS28337.1 - 7.5e-08 32.2 0.0 1.4e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EPS28337.1 - 1.8e-06 28.0 0.0 3.3e-05 23.9 0.0 2.3 1 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPS28337.1 - 0.00077 19.3 0.0 0.0018 18.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPS28337.1 - 0.073 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Response_reg PF00072.19 EPS28340.1 - 3.6e-27 94.6 0.3 6.8e-27 93.6 0.2 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 EPS28340.1 - 4.2e-25 87.6 0.0 7.2e-25 86.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.1 EPS28340.1 - 1e-21 77.2 0.0 8.2e-18 64.7 0.0 2.6 2 0 0 2 2 2 2 PAS domain HisKA PF00512.20 EPS28340.1 - 2.4e-17 62.6 0.1 5.9e-17 61.4 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.19 EPS28340.1 - 8.5e-17 60.9 0.0 2.3e-10 40.2 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.5 EPS28340.1 - 1.8e-12 47.2 0.0 3e-07 30.4 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.1 EPS28340.1 - 0.0059 16.4 0.0 0.03 14.2 0.0 2.1 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.6 EPS28340.1 - 0.021 14.8 0.0 0.049 13.7 0.0 1.7 1 0 0 1 1 1 0 PAS fold Pro-kuma_activ PF09286.6 EPS28341.1 - 4.3e-46 156.5 0.0 7.3e-46 155.7 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EPS28341.1 - 5e-07 29.1 0.4 8.7e-07 28.3 0.3 1.3 1 0 0 1 1 1 1 Subtilase family Aldo_ket_red PF00248.16 EPS28342.1 - 6.8e-45 153.0 0.0 7.9e-45 152.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family XH PF03469.9 EPS28342.1 - 0.11 12.1 0.1 0.52 9.9 0.0 2.0 2 0 0 2 2 2 0 XH domain Lipase_GDSL_2 PF13472.1 EPS28343.1 - 6.7e-19 68.6 3.5 8.8e-19 68.3 2.4 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EPS28343.1 - 2.6e-11 43.8 0.9 3.6e-11 43.3 0.6 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glyco_trans_2_3 PF13632.1 EPS28344.1 - 5.7e-46 156.6 5.1 5.7e-46 156.6 3.6 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EPS28344.1 - 1.7e-05 24.7 0.1 0.0019 18.0 0.1 2.5 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EPS28344.1 - 0.15 11.7 0.1 0.44 10.2 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 2 Glyco_hydro_16 PF00722.16 EPS28345.1 - 1.2e-19 70.3 4.6 2e-19 69.5 3.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 WSC PF01822.14 EPS28346.1 - 9e-35 118.4 27.6 7.9e-19 67.3 8.3 3.2 3 1 0 3 3 3 2 WSC domain Chitin_bind_1 PF00187.14 EPS28346.1 - 6.3e-06 26.0 25.0 6.3e-06 26.0 17.3 5.6 4 3 1 5 5 5 1 Chitin recognition protein Cutinase PF01083.17 EPS28348.1 - 5.8e-46 156.4 1.0 7.1e-46 156.1 0.7 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EPS28348.1 - 0.0048 16.3 0.2 0.0082 15.5 0.0 1.5 2 0 0 2 2 2 1 PE-PPE domain TPIP1 PF15338.1 EPS28348.1 - 0.018 14.8 0.1 0.038 13.8 0.1 1.5 1 0 0 1 1 1 0 p53-regulated apoptosis-inducing protein 1 VirJ PF06057.6 EPS28348.1 - 0.024 14.3 0.0 0.035 13.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_1 PF00561.15 EPS28348.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold CFEM PF05730.6 EPS28349.1 - 1.9e-13 49.9 6.5 2.2e-13 49.8 4.5 1.2 1 0 0 1 1 1 1 CFEM domain Peptidase_C34 PF05413.6 EPS28349.1 - 0.077 13.0 1.1 0.099 12.7 0.7 1.5 1 1 0 1 1 1 0 Putative closterovirus papain-like endopeptidase Glyco_hydro_25 PF01183.15 EPS28350.1 - 1.7e-41 142.0 0.4 2e-41 141.8 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Response_reg PF00072.19 EPS28351.1 - 0.035 14.0 0.0 0.047 13.7 0.0 1.3 1 1 0 1 1 1 0 Response regulator receiver domain Fungal_trans PF04082.13 EPS28352.1 - 4.7e-26 91.2 0.1 1.1e-25 89.9 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS28352.1 - 8.1e-10 38.4 9.5 1.6e-09 37.5 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4175 PF13779.1 EPS28352.1 - 0.18 9.4 13.5 3.7 5.1 10.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) Tim54 PF11711.3 EPS28352.1 - 0.58 8.6 3.7 0.86 8.1 2.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PAT1 PF09770.4 EPS28352.1 - 4.4 5.4 23.9 7.2 4.7 16.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1993 PF09351.5 EPS28353.1 - 1.5e-57 194.0 0.2 1.7e-57 193.9 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) Amidohydro_1 PF01979.15 EPS28354.1 - 1.1e-33 117.3 0.0 1.5e-33 116.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EPS28354.1 - 4.2e-07 30.2 0.0 0.0073 16.3 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 EPS28354.1 - 5e-07 29.2 1.5 0.00029 20.1 0.0 2.9 2 1 1 3 3 3 2 Amidohydrolase family Amidohydro_5 PF13594.1 EPS28354.1 - 3.7e-05 23.4 0.0 8.4e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 EPS28354.1 - 0.00081 18.3 0.0 0.0013 17.7 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase OPT PF03169.10 EPS28355.1 - 4.8e-167 557.1 52.5 5.5e-167 556.9 36.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein IQ PF00612.22 EPS28356.1 - 0.00059 19.2 1.2 0.0018 17.7 0.9 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif AMP-binding PF00501.23 EPS28358.1 - 1.3e-34 119.3 0.0 1.3e-32 112.7 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme NAD_binding_4 PF07993.7 EPS28358.1 - 1.5e-33 115.7 0.0 3.7e-33 114.4 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.16 EPS28358.1 - 4.7e-14 52.4 0.0 7.5e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EPS28358.1 - 3.1e-07 30.5 0.0 1.1e-06 28.8 0.0 2.0 2 0 0 2 2 2 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.12 EPS28358.1 - 4.3e-05 22.5 0.0 0.0038 16.1 0.0 2.3 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EPS28358.1 - 0.0028 17.6 0.0 0.0077 16.2 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EPS28358.1 - 0.0093 14.8 0.0 0.02 13.7 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EPS28358.1 - 0.015 14.0 0.0 0.045 12.4 0.0 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family YpjP PF14005.1 EPS28359.1 - 0.065 13.0 0.8 0.07 12.8 0.5 1.2 1 0 0 1 1 1 0 YpjP-like protein Flexi_CP PF00286.15 EPS28359.1 - 0.079 12.6 4.2 0.089 12.4 2.9 1.0 1 0 0 1 1 1 0 Viral coat protein SseC PF04888.7 EPS28359.1 - 0.14 11.4 14.6 0.15 11.3 10.1 1.0 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Phage_capsid PF05065.8 EPS28359.1 - 0.31 10.1 7.4 0.35 10.0 5.1 1.1 1 0 0 1 1 1 0 Phage capsid family DUF3439 PF11921.3 EPS28359.1 - 0.67 9.7 10.9 0.72 9.6 7.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 EPS28359.1 - 0.77 7.4 6.2 0.8 7.3 4.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Phage_sheath_1 PF04984.9 EPS28359.1 - 1.2 7.4 7.6 1.3 7.3 5.3 1.1 1 0 0 1 1 1 0 Phage tail sheath protein Mor PF08765.6 EPS28359.1 - 1.7 8.4 4.8 6.4 6.5 3.2 1.9 1 1 0 1 1 1 0 Mor transcription activator family Mucin PF01456.12 EPS28359.1 - 2.5 7.8 18.6 2.7 7.7 12.9 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.6 EPS28359.1 - 9.2 4.1 14.8 11 3.8 10.2 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 S-methyl_trans PF02574.11 EPS28360.1 - 0.15 11.2 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Homocysteine S-methyltransferase NmrA PF05368.8 EPS28361.1 - 0.0015 17.8 0.1 0.0019 17.4 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family Mur_ligase PF01225.20 EPS28361.1 - 0.026 14.5 0.0 0.043 13.8 0.0 1.4 1 0 0 1 1 1 0 Mur ligase family, catalytic domain BNR PF02012.15 EPS28362.1 - 0.025 14.3 1.4 0.091 12.6 0.5 2.4 2 0 0 2 2 2 0 BNR/Asp-box repeat HCBP_related PF06594.6 EPS28362.1 - 0.13 11.9 3.0 0.54 9.9 0.0 2.4 2 0 0 2 2 2 0 Haemolysin-type calcium binding protein related domain Sugar_tr PF00083.19 EPS28363.1 - 1.2e-86 291.1 28.1 1.5e-86 290.7 19.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS28363.1 - 8.8e-14 50.9 39.7 9.3e-14 50.8 18.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CBM_4_9 PF02018.12 EPS28364.1 - 0.00047 20.1 1.6 0.00078 19.4 0.1 1.9 2 0 0 2 2 2 1 Carbohydrate binding domain GH114_assoc PF14741.1 EPS28364.1 - 0.019 14.6 0.4 0.053 13.2 0.3 1.8 1 0 0 1 1 1 0 N-terminal glycosyl-hydrolase-114-associated domain PLRV_ORF5 PF01690.12 EPS28364.1 - 6.3 5.8 8.6 13 4.7 6.0 1.5 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Sugar_tr PF00083.19 EPS28365.1 - 3.8e-112 375.1 22.3 4.9e-112 374.7 15.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS28365.1 - 3.6e-22 78.5 35.0 1.3e-15 56.9 12.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Acetyltransf_3 PF13302.1 EPS28366.1 - 3.8e-32 111.3 0.0 4.9e-32 111.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPS28366.1 - 0.00033 20.6 0.0 0.00051 20.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EPS28366.1 - 0.018 14.9 0.0 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Sugar_tr PF00083.19 EPS28367.1 - 3.4e-106 355.5 27.5 4e-106 355.2 19.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS28367.1 - 4.5e-20 71.6 42.0 2.2e-19 69.3 23.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Phtf-FEM1B_bdg PF12129.3 EPS28367.1 - 0.072 12.4 0.2 0.14 11.4 0.1 1.5 1 1 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor F-box-like PF12937.2 EPS28369.1 - 9.7e-07 28.4 0.5 2.3e-06 27.2 0.4 1.7 1 0 0 1 1 1 1 F-box-like Redoxin PF08534.5 EPS28370.1 - 2.4e-38 130.9 0.0 2.7e-38 130.7 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EPS28370.1 - 4.5e-14 52.2 0.0 5.7e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Stirrup PF09061.1 EPS28370.1 - 0.056 13.3 0.0 0.81 9.6 0.0 2.4 3 0 0 3 3 3 0 Stirrup ADH_N PF08240.7 EPS28371.1 - 7.4e-24 83.6 1.9 1.4e-23 82.7 1.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPS28371.1 - 2.5e-16 59.3 0.0 4e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EPS28371.1 - 8.4e-05 21.7 0.3 0.00014 21.1 0.2 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EPS28371.1 - 0.0011 18.5 0.3 0.0011 18.5 0.2 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 EPS28371.1 - 0.0013 18.8 0.0 0.0019 18.2 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_2 PF03446.10 EPS28371.1 - 0.011 15.6 0.1 0.018 14.8 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase McyA_C PF12593.3 EPS28371.1 - 0.015 14.9 0.0 1.8 8.3 0.0 2.6 2 0 0 2 2 2 0 Microcystin synthetase C terminal 3HCDH_N PF02737.13 EPS28371.1 - 0.026 14.1 0.1 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 EPS28371.1 - 0.034 13.9 0.5 0.066 13.0 0.4 1.5 1 0 0 1 1 1 0 ThiF family ApbA PF02558.11 EPS28371.1 - 0.062 12.7 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 EPS28371.1 - 0.074 13.3 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding MAF_flag10 PF01973.13 EPS28371.1 - 0.15 11.5 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF115 MFS_1 PF07690.11 EPS28372.1 - 2.7e-30 105.3 35.6 2.6e-29 102.0 25.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF912 PF06024.7 EPS28372.1 - 0.0023 17.9 0.1 0.0048 16.9 0.0 1.5 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) UL40 PF10682.4 EPS28373.1 - 3.2 7.2 7.0 2.4 7.6 0.1 2.8 2 1 1 3 3 3 0 Glycoprotein of human cytomegalovirus HHV-5 Pheromone PF08015.6 EPS28374.1 - 2.3 9.1 6.7 5.9 7.7 4.7 1.8 1 1 0 1 1 1 0 Fungal mating-type pheromone Pyr_redox_3 PF13738.1 EPS28376.1 - 8.9e-23 81.4 0.1 7.9e-22 78.3 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EPS28376.1 - 1.3e-12 46.7 0.0 3.5e-12 45.3 0.0 1.6 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EPS28376.1 - 4.9e-12 45.4 0.1 3e-11 42.8 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EPS28376.1 - 1.8e-08 34.5 0.0 2.1e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPS28376.1 - 1.6e-06 28.0 0.1 5.4e-06 26.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EPS28376.1 - 0.00078 18.6 0.3 0.0025 16.9 0.1 1.8 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 EPS28376.1 - 0.006 15.1 0.8 0.98 7.8 0.1 2.7 3 0 0 3 3 3 2 HI0933-like protein NAD_binding_9 PF13454.1 EPS28376.1 - 0.012 15.3 1.5 0.071 12.8 0.2 2.5 2 1 0 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.19 EPS28376.1 - 0.024 13.5 0.0 0.63 8.8 0.0 2.6 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EPS28376.1 - 0.027 13.5 0.5 0.25 10.3 0.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPS28376.1 - 0.046 12.5 0.2 0.58 8.9 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.7 EPS28376.1 - 0.062 12.2 0.2 0.12 11.2 0.1 1.6 1 1 0 1 1 1 0 Lycopene cyclase protein CrtC PF07143.6 EPS28377.1 - 1.2e-15 57.6 5.1 4.4e-15 55.7 3.5 1.8 1 1 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) zf-C2H2 PF00096.21 EPS28378.1 - 4.2e-11 42.4 12.1 1.2e-05 25.3 0.8 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EPS28378.1 - 2.5e-08 33.7 9.6 2.5e-06 27.5 1.1 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EPS28378.1 - 2.5e-08 33.6 7.6 0.00065 19.8 0.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EPS28378.1 - 0.00024 21.1 7.1 0.02 15.0 1.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 EPS28378.1 - 0.003 17.6 5.9 0.018 15.2 0.1 2.8 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EPS28378.1 - 0.023 14.6 3.8 1 9.3 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.10 EPS28378.1 - 0.16 11.7 0.2 0.16 11.7 0.1 2.2 2 0 0 2 2 2 0 BED zinc finger zf-met PF12874.2 EPS28378.1 - 0.4 10.9 0.1 0.4 10.9 0.1 2.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DLH PF01738.13 EPS28382.1 - 1.4e-13 50.6 0.0 1.7e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EPS28382.1 - 0.0085 15.8 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Zn_clus PF00172.13 EPS28385.1 - 2.9e-08 33.4 6.5 4.3e-08 32.9 4.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Staygreen PF12638.2 EPS28387.1 - 0.086 12.3 0.0 0.091 12.3 0.0 1.0 1 0 0 1 1 1 0 Staygreen protein AreA_N PF07573.6 EPS28388.1 - 1e-19 70.8 3.6 1e-19 70.8 2.5 3.8 3 0 0 3 3 3 1 Nitrogen regulatory protein AreA N terminus GATA PF00320.22 EPS28388.1 - 1.5e-16 59.4 1.9 3e-16 58.4 1.3 1.5 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 EPS28388.1 - 1.1e-13 50.4 4.4 1.1e-13 50.4 3.0 1.9 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) HSP9_HSP12 PF04119.7 EPS28390.1 - 0.00098 19.1 2.2 0.028 14.4 0.3 2.2 2 0 0 2 2 2 2 Heat shock protein 9/12 Ipi1_N PF12333.3 EPS28391.1 - 4.5e-29 100.4 0.0 4e-28 97.3 0.0 2.2 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation MMS19_C PF12460.3 EPS28391.1 - 0.022 13.5 1.6 0.1 11.3 1.3 1.7 1 1 0 1 1 1 0 RNAPII transcription regulator C-terminal HEAT_2 PF13646.1 EPS28391.1 - 0.038 14.2 0.6 0.13 12.5 0.2 1.9 1 1 1 2 2 2 0 HEAT repeats HEAT PF02985.17 EPS28391.1 - 0.14 12.2 2.8 2 8.7 0.2 3.2 3 0 0 3 3 3 0 HEAT repeat Transp_cyt_pur PF02133.10 EPS28393.1 - 2.8e-86 289.8 41.7 3.4e-86 289.5 28.9 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Pyrid_oxidase_2 PF13883.1 EPS28394.1 - 5.4e-35 120.6 0.0 8.2e-35 120.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Cyclin PF08613.6 EPS28395.1 - 2.7e-14 53.8 0.3 2.7e-14 53.8 0.2 2.1 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EPS28395.1 - 0.011 15.3 0.0 0.024 14.2 0.0 1.6 1 1 0 1 1 1 0 Cyclin, N-terminal domain Aminotran_5 PF00266.14 EPS28398.1 - 2.4e-56 191.1 0.0 4.4e-56 190.2 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EPS28398.1 - 6.6e-09 35.1 0.0 1.2e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EPS28398.1 - 0.00027 19.3 0.0 0.00044 18.6 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Glyco_hydro_47 PF01532.15 EPS28398.1 - 0.025 13.2 0.0 0.033 12.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 47 HTH_AsnC-type PF13404.1 EPS28398.1 - 0.052 13.1 0.1 3.5 7.2 0.0 3.2 3 0 0 3 3 3 0 AsnC-type helix-turn-helix domain Robl_LC7 PF03259.12 EPS28399.1 - 3.2e-06 26.5 1.0 0.018 14.5 0.0 2.9 3 0 0 3 3 3 2 Roadblock/LC7 domain Opi1 PF08618.5 EPS28399.1 - 0.018 13.9 1.7 0.024 13.5 1.2 1.2 1 0 0 1 1 1 0 Transcription factor Opi1 DUF972 PF06156.8 EPS28400.1 - 0.044 14.1 1.0 0.65 10.3 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF972) bZIP_2 PF07716.10 EPS28400.1 - 7.9 6.3 7.2 0.78 9.6 0.7 2.3 2 0 0 2 2 2 0 Basic region leucine zipper SEN1_N PF12726.2 EPS28401.1 - 7.3e-223 741.7 9.1 9.3e-223 741.3 6.3 1.1 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 EPS28401.1 - 6e-68 228.9 0.4 1.6e-67 227.5 0.3 1.8 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 EPS28401.1 - 2.1e-61 206.8 0.0 1e-60 204.5 0.0 2.2 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EPS28401.1 - 1.2e-11 44.2 0.0 3.7e-11 42.6 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EPS28401.1 - 1.3e-09 37.9 0.0 7.3e-06 25.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.16 EPS28401.1 - 4.9e-08 32.6 0.4 2e-06 27.3 0.0 2.6 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 EPS28401.1 - 7.9e-07 28.8 0.1 0.016 14.7 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 EPS28401.1 - 1.6e-05 24.5 0.0 0.00029 20.3 0.0 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_16 PF13191.1 EPS28401.1 - 0.0015 18.5 0.0 0.0056 16.6 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain T2SE PF00437.15 EPS28401.1 - 0.0036 16.2 0.1 0.0096 14.8 0.0 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.1 EPS28401.1 - 0.0052 16.9 0.2 0.089 12.9 0.0 3.2 4 0 0 4 4 4 1 AAA domain AAA_23 PF13476.1 EPS28401.1 - 0.036 14.3 0.4 0.11 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EPS28401.1 - 0.053 12.9 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 EPS28401.1 - 0.081 12.7 0.0 0.23 11.2 0.0 1.8 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit HAD PF12710.2 EPS28403.1 - 1.9e-13 51.0 0.0 5.2e-13 49.5 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EPS28403.1 - 1.4e-12 47.1 0.1 5e-12 45.3 0.0 1.9 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EPS28403.1 - 9.1e-12 44.7 0.0 2.5e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 EPS28403.1 - 3e-10 40.8 3.4 5.5e-09 36.7 2.4 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EPS28403.1 - 0.009 15.6 0.3 0.028 13.9 0.2 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EPS28403.1 - 0.051 13.7 0.0 0.24 11.6 0.0 2.0 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase N6-adenineMlase PF10237.4 EPS28404.1 - 0.027 14.1 0.1 0.066 12.8 0.0 1.6 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase vATP-synt_E PF01991.13 EPS28405.1 - 1.5e-58 197.3 10.7 1.7e-58 197.1 7.4 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit IBB PF01749.15 EPS28405.1 - 0.55 10.4 5.4 11 6.2 0.1 2.6 2 0 0 2 2 2 0 Importin beta binding domain Mg_trans_NIPA PF05653.9 EPS28406.1 - 5.8e-14 51.7 11.2 1.5e-09 37.3 1.7 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EamA PF00892.15 EPS28406.1 - 3.6e-06 27.0 0.6 3.6e-06 27.0 0.4 2.8 3 0 0 3 3 3 2 EamA-like transporter family DUF202 PF02656.10 EPS28406.1 - 0.16 12.1 7.8 1.6 9.0 0.5 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Multi_Drug_Res PF00893.14 EPS28406.1 - 1.2 9.6 8.0 9.5 6.7 0.2 2.9 2 1 0 2 2 2 0 Small Multidrug Resistance protein SRF-TF PF00319.13 EPS28407.1 - 1.4e-23 81.8 0.2 1.9e-23 81.3 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CDC45 PF02724.9 EPS28407.1 - 0.027 12.5 0.2 0.037 12.0 0.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF604 PF04646.7 EPS28408.1 - 0.00037 19.7 0.0 0.0006 19.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.11 EPS28408.1 - 0.001 18.3 0.0 0.0023 17.2 0.0 1.5 1 1 0 1 1 1 1 Fringe-like Ser_hydrolase PF06821.8 EPS28408.1 - 0.13 11.8 0.3 0.24 11.0 0.2 1.4 1 0 0 1 1 1 0 Serine hydrolase GDI PF00996.13 EPS28410.1 - 2.7e-39 134.7 0.0 3.3e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 EPS28410.1 - 0.045 13.7 0.0 0.33 11.0 0.0 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pro_isomerase PF00160.16 EPS28411.1 - 4.2e-52 176.4 0.1 4.8e-52 176.2 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_A22B PF04258.8 EPS28412.1 - 1e-57 195.8 0.1 3e-57 194.3 0.0 1.6 1 1 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 EPS28412.1 - 5.9e-05 22.3 2.6 5.9e-05 22.3 1.8 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1119) RNase_PH PF01138.16 EPS28413.1 - 2.7e-13 50.3 0.9 8.8e-12 45.4 0.6 2.3 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 NAD_binding_6 PF08030.7 EPS28414.1 - 4.2e-24 85.2 0.0 6e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EPS28414.1 - 1.6e-15 57.3 9.9 3.3e-15 56.2 5.6 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EPS28414.1 - 5.3e-15 55.1 0.0 1.3e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EPS28414.1 - 0.019 15.5 0.0 2.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Acetyltransf_1 PF00583.19 EPS28415.1 - 3.7e-07 30.0 0.2 2.4e-06 27.4 0.2 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPS28415.1 - 0.018 15.1 0.0 0.038 14.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sgf11 PF08209.6 EPS28416.1 - 9.4e-09 34.4 0.3 9.4e-09 34.4 0.2 2.0 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-C2HC5 PF06221.8 EPS28418.1 - 3.4e-23 81.1 5.2 5.3e-23 80.5 3.6 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type p450 PF00067.17 EPS28419.1 - 6.8e-67 225.9 0.0 8.8e-67 225.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mpv17_PMP22 PF04117.7 EPS28420.1 - 3.6e-15 55.3 0.1 9e-15 54.0 0.0 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family MFS_1 PF07690.11 EPS28421.1 - 1.9e-38 132.0 56.9 1.9e-38 132.0 39.5 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Aldo_ket_red PF00248.16 EPS28423.1 - 4e-68 229.2 0.0 4.6e-68 229.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Hexokinase_2 PF03727.11 EPS28424.1 - 7.7e-72 241.4 0.0 1e-71 240.9 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EPS28424.1 - 2.2e-62 210.0 0.0 3.2e-62 209.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase DUF1690 PF07956.6 EPS28425.1 - 8.8e-30 103.5 3.4 5e-14 52.4 0.0 2.1 2 0 0 2 2 2 2 Protein of Unknown function (DUF1690) Herpes_UL25 PF01499.11 EPS28425.1 - 0.065 11.5 0.2 0.079 11.2 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF3391 PF11871.3 EPS28425.1 - 1.1 9.5 6.9 0.5 10.5 0.5 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) Phasin PF05597.6 EPS28425.1 - 1.1 8.9 5.6 0.6 9.8 0.6 2.1 2 1 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) POP1 PF06978.6 EPS28426.1 - 4.3e-66 222.1 18.1 9.3e-66 221.0 12.5 1.6 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 EPS28426.1 - 2.8e-30 104.0 1.0 8.9e-30 102.3 0.7 2.0 1 0 0 1 1 1 1 POPLD (NUC188) domain TRI12 PF06609.8 EPS28427.1 - 1.4e-33 116.0 33.0 1.6e-33 115.8 22.2 1.4 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EPS28427.1 - 6.9e-13 48.0 66.7 5e-12 45.1 42.1 3.2 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS28427.1 - 8.4e-07 27.9 13.1 8.4e-07 27.9 9.1 4.2 2 1 2 4 4 4 2 Sugar (and other) transporter Cation_ATPase_C PF00689.16 EPS28427.1 - 0.089 12.3 8.4 0.026 14.0 2.7 2.5 1 1 0 1 1 1 0 Cation transporting ATPase, C-terminus 4HBT PF03061.17 EPS28428.1 - 1.3e-05 25.2 0.1 2.2e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily UCH PF00443.24 EPS28429.1 - 2.3e-54 184.3 0.2 3.1e-54 183.9 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPS28429.1 - 1.7e-14 53.9 4.9 5.4e-14 52.3 3.4 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EPS28429.1 - 1.4e-10 40.4 0.0 4.4e-10 38.8 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 EPS28429.1 - 0.093 12.9 0.0 0.37 11.0 0.0 2.1 1 0 0 1 1 1 0 Ubiquitin-like domain ARPC4 PF05856.7 EPS28430.1 - 1.1e-73 246.2 3.1 1.2e-73 246.1 2.2 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) RRM_1 PF00076.17 EPS28431.1 - 6.2e-05 22.5 0.0 0.00013 21.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS28431.1 - 0.0029 17.5 0.0 0.0081 16.1 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2461 PF09365.5 EPS28432.1 - 7.9e-71 237.8 0.0 1.2e-70 237.2 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) CDC45 PF02724.9 EPS28432.1 - 1.1 7.1 6.8 0.71 7.8 3.7 1.4 2 0 0 2 2 2 0 CDC45-like protein Nop14 PF04147.7 EPS28432.1 - 6.1 4.6 14.1 9.5 3.9 9.8 1.2 1 0 0 1 1 1 0 Nop14-like family Zn_clus PF00172.13 EPS28433.1 - 9.4e-09 35.0 7.8 1.3e-08 34.5 5.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hep_59 PF07052.6 EPS28434.1 - 0.048 14.0 0.2 0.062 13.6 0.2 1.1 1 0 0 1 1 1 0 Hepatocellular carcinoma-associated antigen 59 MerT PF02411.10 EPS28434.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 MerT mercuric transport protein Pkinase PF00069.20 EPS28435.1 - 1.5e-71 240.6 0.0 2.1e-71 240.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS28435.1 - 1.1e-37 129.5 0.0 6e-35 120.5 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EPS28435.1 - 1.6e-05 24.7 0.3 0.0026 17.5 0.0 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EPS28435.1 - 0.00079 18.4 0.0 0.0019 17.2 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EPS28435.1 - 0.0012 17.9 0.0 0.0031 16.6 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EPS28435.1 - 0.006 16.1 0.1 0.026 14.1 0.0 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase DUF844 PF05815.6 EPS28435.1 - 0.16 10.7 0.0 0.31 9.8 0.0 1.4 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) Redoxin PF08534.5 EPS28436.1 - 2.2e-34 118.1 0.0 2.4e-34 117.9 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EPS28436.1 - 6.1e-16 58.2 0.0 8.2e-16 57.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family WD40 PF00400.27 EPS28437.1 - 2.9e-12 45.9 17.7 0.00014 21.5 0.0 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat zf-C3HC4 PF00097.20 EPS28437.1 - 0.0026 17.3 1.5 0.0026 17.3 1.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RWD PF05773.17 EPS28437.1 - 0.0054 16.6 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 RWD domain zf-C3HC4_2 PF13923.1 EPS28437.1 - 0.0065 16.4 7.1 0.0065 16.4 4.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) UQ_con PF00179.21 EPS28438.1 - 1.8e-46 157.0 0.0 2.1e-46 156.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EPS28438.1 - 6.5e-05 22.7 0.0 8.2e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EPS28438.1 - 0.01 15.4 0.1 0.021 14.5 0.0 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.17 EPS28438.1 - 0.057 13.3 0.0 0.066 13.1 0.0 1.3 1 0 0 1 1 1 0 RWD domain WH1 PF00568.18 EPS28439.1 - 2.2e-30 104.6 0.0 2.9e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 EPS28439.1 - 0.1 12.2 2.5 0.42 10.2 1.8 2.0 1 1 0 1 1 1 0 WH2 motif BNIP3 PF06553.7 EPS28440.1 - 0.094 12.0 1.0 0.11 11.8 0.7 1.0 1 0 0 1 1 1 0 BNIP3 ERCC4 PF02732.10 EPS28441.1 - 6.2e-25 87.6 0.0 2.1e-24 85.9 0.0 2.0 1 0 0 1 1 1 1 ERCC4 domain HHH_5 PF14520.1 EPS28441.1 - 2.1e-05 24.5 0.0 9.4e-05 22.5 0.0 2.2 1 1 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.2 EPS28441.1 - 0.092 12.6 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Peptidase_S41 PF03572.13 EPS28442.1 - 9e-12 44.7 0.0 1.7e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S41 eIF-1a PF01176.14 EPS28443.1 - 2.1e-28 97.5 0.1 3e-28 97.0 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 PTCB-BRCT PF12738.2 EPS28445.1 - 1.8e-11 43.6 0.0 3.4e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EPS28445.1 - 2.4e-07 30.8 0.0 4.2e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain fn3 PF00041.16 EPS28445.1 - 0.00043 20.3 0.0 0.0011 19.0 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain DUF3006 PF11213.3 EPS28445.1 - 0.00064 19.4 0.0 0.0015 18.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) HpaP PF09483.5 EPS28445.1 - 7.4 6.4 10.7 14 5.6 7.4 1.5 1 0 0 1 1 1 0 Type III secretion protein (HpaP) Aminotran_1_2 PF00155.16 EPS28446.1 - 1.5e-75 254.4 0.0 1.7e-75 254.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Abhydrolase_3 PF07859.8 EPS28447.1 - 3.5e-58 196.6 0.0 4.6e-58 196.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EPS28447.1 - 0.00084 18.6 0.0 0.031 13.4 0.0 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 EPS28447.1 - 0.088 12.0 0.0 0.36 10.0 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family Esterase_phd PF10503.4 EPS28447.1 - 0.089 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase Abhydrolase_5 PF12695.2 EPS28447.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lyase_1 PF00206.15 EPS28448.1 - 5.1e-110 367.5 0.0 7.2e-110 367.0 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 EPS28448.1 - 8.4e-22 76.9 0.0 3.1e-21 75.1 0.0 2.1 2 0 0 2 2 2 1 Fumarase C C-terminus X_fast-SP_rel PF06669.6 EPS28449.1 - 0.011 15.6 0.0 0.013 15.3 0.0 1.1 1 0 0 1 1 1 0 Xylella fastidiosa surface protein related Acetyltransf_7 PF13508.1 EPS28450.1 - 7.1e-09 35.7 0.1 1.1e-08 35.0 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPS28450.1 - 4.1e-07 29.9 0.0 7.3e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Ribosomal_L24e PF01246.15 EPS28451.1 - 1.5e-30 104.8 0.3 1.5e-30 104.8 0.2 2.2 2 1 1 3 3 3 1 Ribosomal protein L24e DUF775 PF05603.7 EPS28451.1 - 0.098 12.1 0.5 0.12 11.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF775) WTX PF09422.5 EPS28451.1 - 0.62 8.9 7.0 0.79 8.6 4.9 1.1 1 0 0 1 1 1 0 WTX protein Metallophos PF00149.23 EPS28453.1 - 4.3e-40 137.2 0.5 1e-39 136.0 0.4 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 EPS28453.1 - 2.2e-17 62.8 0.1 8.9e-17 60.9 0.1 2.1 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 EPS28453.1 - 4.6e-10 38.6 0.5 6.7e-09 34.8 0.4 2.0 2 0 0 2 2 2 1 PhoD-like phosphatase Metallophos_2 PF12850.2 EPS28453.1 - 0.077 12.8 0.0 0.28 11.0 0.0 2.0 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain CorA PF01544.13 EPS28454.1 - 6.4e-08 31.9 0.0 1e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Sporozoite_P67 PF05642.6 EPS28454.1 - 0.0089 13.9 0.6 0.011 13.6 0.4 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Melibiase PF02065.13 EPS28455.1 - 2.3e-41 141.7 0.0 3.6e-22 78.6 0.0 2.2 2 0 0 2 2 2 2 Melibiase AdoMet_MTase PF07757.8 EPS28456.1 - 2.6e-36 124.1 0.0 5.3e-36 123.1 0.0 1.5 1 1 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase His_Phos_1 PF00300.17 EPS28457.1 - 7.2e-32 110.6 0.0 8.5e-32 110.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF1246 PF06849.7 EPS28457.1 - 0.0044 16.7 0.0 0.0066 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1246) DASH_Hsk3 PF08227.6 EPS28458.1 - 1.3e-19 70.0 2.7 2e-19 69.4 1.9 1.3 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like Mating_C PF12737.2 EPS28458.1 - 0.014 14.2 0.6 0.017 14.0 0.4 1.1 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 ApbA PF02558.11 EPS28460.1 - 5.3e-25 87.6 0.0 7.6e-25 87.1 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EPS28460.1 - 1.6e-20 73.3 0.0 2.6e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DEAD PF00270.24 EPS28462.1 - 1.2e-34 119.2 0.0 2e-34 118.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPS28462.1 - 5e-24 83.9 0.0 4.4e-23 80.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPS28462.1 - 1.8e-05 24.6 0.1 5.3e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Rpr2 PF04032.11 EPS28463.1 - 6.5e-22 77.2 6.6 6.5e-22 77.2 4.5 1.8 2 1 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain E_Pc_C PF06752.7 EPS28463.1 - 0.0079 15.7 1.5 0.01 15.3 1.1 1.1 1 0 0 1 1 1 1 Enhancer of Polycomb C-terminus GFA PF04828.9 EPS28463.1 - 0.2 11.6 0.1 0.2 11.6 0.1 2.4 2 1 0 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme DUF4482 PF14818.1 EPS28463.1 - 0.8 10.3 8.0 0.17 12.5 2.5 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4482) Striatin PF08232.7 EPS28463.1 - 3.8 7.8 8.2 0.33 11.2 1.7 1.9 1 1 1 2 2 2 0 Striatin family ESX-1_EspG PF14011.1 EPS28464.1 - 0.0061 15.8 0.0 0.0076 15.5 0.0 1.1 1 0 0 1 1 1 1 EspG family FHA PF00498.21 EPS28464.1 - 0.12 12.5 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 FHA domain Glyco_hydro_3_C PF01915.17 EPS28465.1 - 0.012 15.1 0.0 0.015 14.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain Syntaxin PF00804.20 EPS28465.1 - 0.015 15.4 2.9 0.66 10.1 0.2 2.5 1 1 1 2 2 2 0 Syntaxin DUF2365 PF10157.4 EPS28465.1 - 0.032 14.1 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) Vps51 PF08700.6 EPS28465.1 - 0.053 13.3 2.1 3.3 7.6 0.8 2.9 1 1 1 2 2 2 0 Vps51/Vps67 Baculo_PEP_C PF04513.7 EPS28465.1 - 0.08 12.7 0.1 0.31 10.8 0.1 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 EPS28465.1 - 0.17 11.6 0.8 1.5 8.6 0.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) KKLCAg1 PF15204.1 EPS28465.1 - 0.26 11.3 1.3 0.31 11.1 0.0 1.8 2 0 0 2 2 2 0 Kita-kyushu lung cancer antigen 1 Wbp11 PF09429.5 EPS28466.1 - 1.4e-22 79.4 15.2 1.4e-22 79.4 10.5 2.6 3 0 0 3 3 3 1 WW domain binding protein 11 ECH PF00378.15 EPS28467.1 - 6.8e-47 159.6 0.0 8.4e-47 159.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Acetyltransf_8 PF13523.1 EPS28468.1 - 2.7e-33 114.9 0.1 3.8e-33 114.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ABC_membrane PF00664.18 EPS28469.1 - 1.2e-77 261.0 23.2 3.4e-46 157.8 3.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EPS28469.1 - 8.9e-61 204.1 0.0 1.4e-30 106.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EPS28469.1 - 3.5e-17 62.3 0.6 2.4e-05 23.7 0.0 4.4 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EPS28469.1 - 2.9e-09 36.3 0.1 0.0028 17.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 EPS28469.1 - 4.3e-09 36.7 1.2 0.056 13.4 0.0 4.2 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EPS28469.1 - 1.3e-08 35.0 2.7 0.00036 20.5 0.1 3.1 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EPS28469.1 - 1.5e-07 31.6 0.4 0.44 10.6 0.2 4.4 3 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EPS28469.1 - 5.5e-07 30.4 0.0 0.029 15.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 EPS28469.1 - 5e-06 25.3 0.3 0.00041 19.0 0.0 2.5 3 0 0 3 3 3 1 Predicted ATPase of the ABC class AAA_25 PF13481.1 EPS28469.1 - 8.3e-06 25.3 0.2 0.3 10.4 0.0 4.3 4 0 0 4 4 4 2 AAA domain AAA_30 PF13604.1 EPS28469.1 - 2.8e-05 23.7 0.2 0.42 10.1 0.0 4.1 4 0 0 4 4 4 1 AAA domain DUF258 PF03193.11 EPS28469.1 - 2.9e-05 23.3 0.0 0.062 12.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 EPS28469.1 - 7.4e-05 23.1 0.1 0.58 10.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 EPS28469.1 - 0.00016 21.8 1.6 3.2 7.9 0.2 4.3 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EPS28469.1 - 0.00017 21.4 0.6 0.84 9.5 0.0 2.8 3 0 0 3 3 2 2 AAA domain SbcCD_C PF13558.1 EPS28469.1 - 0.00022 21.0 0.2 1.4 8.9 0.1 3.4 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 EPS28469.1 - 0.00062 19.5 0.0 0.91 9.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) DUF87 PF01935.12 EPS28469.1 - 0.001 18.9 0.1 0.3 10.8 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_18 PF13238.1 EPS28469.1 - 0.0011 19.2 0.0 2 8.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EPS28469.1 - 0.0012 18.5 0.7 0.66 9.7 0.0 3.1 3 0 0 3 3 2 1 Part of AAA domain Zeta_toxin PF06414.7 EPS28469.1 - 0.01 14.9 0.0 1.3 8.0 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin APS_kinase PF01583.15 EPS28469.1 - 0.014 15.0 0.0 4 7.0 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase MMR_HSR1 PF01926.18 EPS28469.1 - 0.015 15.2 0.0 5 7.1 0.0 3.0 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_10 PF12846.2 EPS28469.1 - 0.019 14.3 2.6 2.9 7.2 0.2 3.2 2 1 1 3 3 3 0 AAA-like domain AAA_14 PF13173.1 EPS28469.1 - 0.037 13.9 0.0 14 5.5 0.0 3.1 3 0 0 3 3 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EPS28469.1 - 0.039 13.4 0.0 0.42 10.0 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family SRP54 PF00448.17 EPS28469.1 - 0.052 12.9 0.2 14 5.0 0.0 3.0 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain G-alpha PF00503.15 EPS28469.1 - 0.056 12.1 0.0 8.6 4.9 0.0 2.4 2 0 0 2 2 2 0 G-protein alpha subunit NB-ARC PF00931.17 EPS28469.1 - 0.11 11.2 0.1 10 4.9 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AMP-binding PF00501.23 EPS28470.1 - 7.1e-87 291.4 0.0 2.5e-78 263.3 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EPS28470.1 - 8.5e-65 218.5 0.0 9.4e-33 113.3 0.0 3.0 2 1 0 2 2 2 2 Condensation domain PP-binding PF00550.20 EPS28470.1 - 2.2e-25 88.6 0.2 2.5e-12 46.8 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EPS28470.1 - 1.8e-05 25.5 1.9 0.25 12.3 0.3 3.4 2 1 0 2 2 2 2 AMP-binding enzyme C-terminal domain DUF1749 PF08538.5 EPS28471.1 - 1.1e-98 329.9 0.0 1.2e-98 329.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 EPS28471.1 - 8.1e-07 29.1 0.0 1.3e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPS28471.1 - 5.1e-05 23.0 0.0 0.00011 22.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EPS28471.1 - 0.0039 16.7 0.0 0.0094 15.5 0.0 1.7 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_1 PF00561.15 EPS28471.1 - 0.032 13.7 0.0 0.094 12.2 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF900 PF05990.7 EPS28471.1 - 0.047 13.0 0.0 0.12 11.6 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Pkinase PF00069.20 EPS28472.1 - 2.5e-59 200.5 0.0 4.7e-59 199.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS28472.1 - 6.3e-37 127.0 0.0 1.3e-25 90.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EPS28472.1 - 0.0075 15.2 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EPS28472.1 - 0.13 11.9 0.5 0.51 10.0 0.0 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family BTB PF00651.26 EPS28473.1 - 5.6e-27 93.9 0.0 5.8e-14 52.0 0.1 2.8 2 0 0 2 2 2 2 BTB/POZ domain Ank_2 PF12796.2 EPS28473.1 - 1.1e-09 38.4 0.0 3.1e-09 37.0 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPS28473.1 - 8.6e-09 35.6 0.0 4.1e-08 33.5 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 EPS28473.1 - 1.1e-08 34.5 0.3 8e-06 25.4 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EPS28473.1 - 2.1e-07 30.9 0.1 1.4e-06 28.3 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPS28473.1 - 0.0011 18.9 0.1 0.013 15.6 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat DUF3342 PF11822.3 EPS28473.1 - 0.041 13.0 0.1 0.087 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3342) DUF4446 PF14584.1 EPS28474.1 - 0.037 13.8 1.6 0.046 13.5 1.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Fmp27_WPPW PF10359.4 EPS28474.1 - 0.11 10.8 1.0 0.13 10.6 0.7 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain FTR1 PF03239.9 EPS28474.1 - 0.13 11.2 0.1 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Iron permease FTR1 family FlxA PF14282.1 EPS28474.1 - 0.18 11.7 5.8 2.9 7.8 4.0 2.0 1 1 0 1 1 1 0 FlxA-like protein MxiH PF09392.5 EPS28474.1 - 0.33 11.5 2.3 0.76 10.3 0.8 1.9 1 1 1 2 2 2 0 Type III secretion needle MxiH like DUF4200 PF13863.1 EPS28474.1 - 0.35 10.8 7.4 0.44 10.5 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Osmo_CC PF08946.5 EPS28474.1 - 0.63 10.1 6.6 11 6.1 0.0 3.0 1 1 2 3 3 3 0 Osmosensory transporter coiled coil DUF4224 PF13986.1 EPS28474.1 - 3.3 7.3 6.1 2.7 7.5 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4224) SMC_N PF02463.14 EPS28475.1 - 2.9e-23 82.2 0.0 1.7e-22 79.7 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EPS28475.1 - 4.9e-12 46.6 16.5 4.9e-12 46.6 11.4 4.7 2 2 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EPS28475.1 - 2.7e-05 24.3 0.0 0.001 19.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EPS28475.1 - 5.9e-05 22.5 0.0 0.00019 20.9 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_13 PF13166.1 EPS28475.1 - 0.045 12.2 60.3 0.1 11.0 0.0 4.7 3 2 1 4 4 4 0 AAA domain AAA_25 PF13481.1 EPS28475.1 - 0.06 12.7 1.3 0.12 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EPS28475.1 - 0.12 12.1 0.0 0.37 10.5 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain HrpB7 PF09486.5 EPS28475.1 - 0.33 10.8 0.0 0.33 10.8 0.0 6.9 3 2 2 6 6 6 0 Bacterial type III secretion protein (HrpB7) Reo_sigmaC PF04582.7 EPS28475.1 - 0.44 9.6 15.3 5.3 6.1 0.2 4.0 4 1 1 5 5 5 0 Reovirus sigma C capsid protein zf-C2H2 PF00096.21 EPS28479.1 - 3e-06 27.2 17.3 0.0025 18.0 3.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EPS28479.1 - 4.1e-05 23.6 2.6 4.1e-05 23.6 1.8 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EPS28479.1 - 0.082 13.2 15.0 0.27 11.6 2.6 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.2 EPS28479.1 - 0.16 12.2 4.1 0.34 11.1 1.4 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zn-ribbon_8 PF09723.5 EPS28479.1 - 0.17 11.8 1.2 4.2 7.4 0.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-BED PF02892.10 EPS28479.1 - 0.23 11.2 9.0 0.4 10.4 0.8 2.5 1 1 1 2 2 2 0 BED zinc finger Spc7_N PF15402.1 EPS28479.1 - 6.7 4.5 11.0 9.2 4.1 7.7 1.2 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Lipase_3 PF01764.20 EPS28480.1 - 5.1e-14 52.0 0.0 4.1e-13 49.1 0.0 2.2 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EPS28480.1 - 0.00032 20.6 0.1 0.00074 19.4 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPS28480.1 - 0.0071 16.1 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family FMN_dh PF01070.13 EPS28481.1 - 3e-125 417.7 0.0 3.4e-125 417.5 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.9 EPS28481.1 - 8.2e-06 25.0 0.4 0.08 12.0 0.0 2.6 3 0 0 3 3 3 2 Thiazole biosynthesis protein ThiG NMO PF03060.10 EPS28481.1 - 0.0004 19.6 1.2 0.0007 18.8 0.9 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.12 EPS28481.1 - 0.0005 19.0 0.2 0.00081 18.3 0.2 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EPS28481.1 - 0.0027 16.6 0.8 0.0056 15.6 0.1 1.8 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 EPS28481.1 - 0.024 13.9 0.9 1.4 8.0 0.1 2.7 2 1 1 3 3 3 0 Histidine biosynthesis protein IGPS PF00218.16 EPS28481.1 - 0.12 11.4 0.2 0.55 9.2 0.1 1.9 1 1 1 2 2 2 0 Indole-3-glycerol phosphate synthase MFS_1 PF07690.11 EPS28482.1 - 3.2e-34 118.2 27.7 3.2e-34 118.2 19.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF539 PF04400.8 EPS28482.1 - 0.22 11.0 0.1 0.37 10.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF539) His_Phos_2 PF00328.17 EPS28483.1 - 4.6e-30 105.1 0.0 5.7e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) NAC PF01849.13 EPS28485.1 - 8.6e-21 73.2 0.0 1.6e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 NAC domain FSH1 PF03959.8 EPS28486.1 - 6.6e-37 127.0 0.0 8e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EPS28486.1 - 1.1e-05 25.4 0.1 3.5e-05 23.8 0.1 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPS28486.1 - 9.7e-05 22.1 0.0 0.00013 21.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EPS28486.1 - 0.0016 17.9 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase PE-PPE PF08237.6 EPS28486.1 - 0.0025 17.2 0.0 0.0035 16.7 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Glyco_trans_4_4 PF13579.1 EPS28486.1 - 0.0036 17.4 0.0 0.0043 17.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain DUF3089 PF11288.3 EPS28486.1 - 0.092 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Abhydrolase_2 PF02230.11 EPS28487.1 - 2e-57 194.1 0.0 2.3e-57 193.9 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EPS28487.1 - 3e-14 52.9 0.0 3.8e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPS28487.1 - 8.6e-09 35.6 0.0 0.00078 19.3 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EPS28487.1 - 3e-06 26.6 0.2 0.00021 20.5 0.0 2.5 3 0 0 3 3 3 1 Prolyl oligopeptidase family FSH1 PF03959.8 EPS28487.1 - 0.00015 21.3 0.0 0.0006 19.3 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) BAAT_C PF08840.6 EPS28487.1 - 0.0053 16.4 0.0 0.032 13.9 0.0 2.0 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 EPS28487.1 - 0.027 14.0 0.0 0.085 12.4 0.0 1.7 1 1 1 2 2 2 0 alpha/beta hydrolase fold LIP PF03583.9 EPS28487.1 - 0.03 13.5 0.0 0.12 11.5 0.0 1.7 1 1 0 2 2 2 0 Secretory lipase DUF2974 PF11187.3 EPS28487.1 - 0.18 11.1 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) MARVEL PF01284.18 EPS28488.1 - 8.9e-05 22.3 13.5 0.00014 21.6 9.2 1.3 1 1 0 1 1 1 1 Membrane-associating domain DUF3611 PF12263.3 EPS28488.1 - 0.083 12.2 1.3 0.15 11.4 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3611) Tetraspannin PF00335.15 EPS28488.1 - 0.18 11.0 8.1 1.2 8.3 6.8 1.5 2 0 0 2 2 2 0 Tetraspanin family PepSY_2 PF13670.1 EPS28489.1 - 0.082 12.8 2.9 3.7 7.5 2.3 2.2 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain AATase PF07247.7 EPS28490.1 - 1.4e-22 79.9 0.0 4.3e-22 78.3 0.0 1.6 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 EPS28490.1 - 0.0023 16.8 0.0 0.047 12.5 0.0 2.6 2 1 0 2 2 2 1 Condensation domain RAP1 PF07218.6 EPS28491.1 - 5.1 5.0 6.1 6.7 4.6 4.2 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ctr PF04145.10 EPS28492.1 - 4.4e-35 120.8 0.4 5.2e-35 120.5 0.3 1.1 1 0 0 1 1 1 1 Ctr copper transporter family FAD_binding_8 PF08022.7 EPS28493.1 - 6.1e-21 74.2 0.0 1.9e-20 72.6 0.0 1.8 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.14 EPS28493.1 - 2.4e-17 63.1 10.0 5e-17 62.1 6.9 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EPS28493.1 - 5e-16 58.9 0.0 1.5e-15 57.4 0.0 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.19 EPS28493.1 - 0.004 17.2 0.0 0.013 15.5 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EPS28493.1 - 0.16 12.5 0.0 39 4.8 0.0 2.7 3 0 0 3 3 3 0 Oxidoreductase NAD-binding domain DUF1687 PF07955.6 EPS28494.1 - 1.7e-10 40.9 0.0 1.1e-09 38.3 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) Pkinase PF00069.20 EPS28495.1 - 6.3e-57 192.6 0.0 4.6e-56 189.8 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS28495.1 - 2.1e-28 99.0 0.0 2.9e-20 72.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 EPS28495.1 - 1.3e-05 25.5 0.2 1.3e-05 25.5 0.2 2.0 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 EPS28495.1 - 0.00014 20.9 0.1 0.0011 17.9 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EPS28495.1 - 0.00047 19.9 4.7 0.084 12.5 0.0 3.5 3 1 1 4 4 4 2 Phosphotransferase enzyme family DUF605 PF04652.11 EPS28495.1 - 1.8 7.8 17.9 2.8 7.2 12.4 1.2 1 0 0 1 1 1 0 Vta1 like Fungal_trans PF04082.13 EPS28496.1 - 7.8e-22 77.3 3.4 7.8e-22 77.3 2.4 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain CCDC144C PF14915.1 EPS28496.1 - 0.2 10.5 0.0 0.31 9.9 0.0 1.2 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Epimerase PF01370.16 EPS28497.1 - 9.9e-29 100.4 0.0 1.6e-28 99.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EPS28497.1 - 1.9e-09 37.8 0.0 1e-08 35.4 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EPS28497.1 - 3.7e-09 35.8 0.0 1.1e-08 34.3 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EPS28497.1 - 4.9e-09 35.4 0.1 2.4e-07 29.9 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 EPS28497.1 - 2.3e-08 33.0 0.2 9.8e-08 31.0 0.1 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EPS28497.1 - 0.00046 19.1 0.0 0.0034 16.3 0.0 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EPS28497.1 - 0.0091 15.9 0.1 0.024 14.5 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EPS28497.1 - 0.014 14.6 0.0 0.022 13.9 0.0 1.5 1 1 0 1 1 1 0 NmrA-like family KR PF08659.5 EPS28497.1 - 0.02 14.5 0.2 0.099 12.2 0.1 1.9 1 1 0 1 1 1 0 KR domain ILVD_EDD PF00920.16 EPS28498.1 - 1.1e-157 525.6 0.0 1.2e-157 525.4 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family Fungal_trans_2 PF11951.3 EPS28500.1 - 5e-10 38.5 0.1 5.5e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain APH PF01636.18 EPS28503.1 - 6.1e-12 45.7 0.0 4.3e-10 39.7 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 EPS28503.1 - 0.01 14.8 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase Pkinase_Tyr PF07714.12 EPS28503.1 - 0.02 13.9 0.0 0.034 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase TrkH PF02386.11 EPS28504.1 - 2e-106 355.5 7.6 1.1e-103 346.6 3.0 2.2 2 0 0 2 2 2 2 Cation transport protein MSP PF01716.13 EPS28504.1 - 0.014 14.4 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 Manganese-stabilising protein / photosystem II polypeptide ICL PF00463.16 EPS28505.1 - 6.1e-193 641.7 0.0 7e-193 641.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EPS28505.1 - 2e-09 37.0 0.0 5.4e-09 35.6 0.0 1.6 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.13 EPS28505.1 - 0.15 11.5 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain Glyco_hydro_72 PF03198.9 EPS28506.1 - 7.9e-127 422.5 7.2 1.1e-126 422.1 5.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EPS28506.1 - 7.4e-26 90.4 7.5 2.4e-25 88.7 5.2 2.0 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.13 EPS28506.1 - 2.7e-06 26.8 0.5 4.5e-06 26.0 0.3 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) MFS_1 PF07690.11 EPS28507.1 - 3.6e-38 131.1 46.6 1.7e-37 128.9 30.2 3.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPS28507.1 - 7.8e-15 54.0 14.9 1.2e-14 53.4 10.3 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) E1-E2_ATPase PF00122.15 EPS28507.1 - 0.49 9.3 4.2 1.5 7.8 2.9 1.9 1 1 0 1 1 1 0 E1-E2 ATPase FSH1 PF03959.8 EPS28508.1 - 1.1e-27 96.8 0.0 3.1e-27 95.4 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EPS28508.1 - 0.075 12.7 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family ketoacyl-synt PF00109.21 EPS28509.1 - 7.2e-76 255.0 0.0 1.7e-75 253.8 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EPS28509.1 - 1.5e-58 198.6 0.6 2.4e-58 197.9 0.4 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EPS28509.1 - 3.3e-44 150.7 0.1 8.7e-44 149.3 0.1 1.8 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 EPS28509.1 - 4.7e-41 140.8 0.0 7.2e-41 140.2 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 EPS28509.1 - 2.5e-36 124.1 2.0 8.3e-36 122.4 0.0 2.9 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EPS28509.1 - 3e-35 121.5 0.6 3e-35 121.5 0.4 2.4 3 0 0 3 3 2 1 short chain dehydrogenase Methyltransf_12 PF08242.7 EPS28509.1 - 2.7e-19 69.4 0.0 8.4e-19 67.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 EPS28509.1 - 2.8e-18 65.7 0.2 4.4e-17 61.8 0.0 2.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 EPS28509.1 - 2e-14 53.6 0.0 6.6e-14 51.9 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPS28509.1 - 7.4e-10 39.1 0.0 2.2e-09 37.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPS28509.1 - 6.7e-09 35.5 0.0 1.6e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS28509.1 - 7.6e-08 32.9 0.0 5.7e-07 30.1 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 EPS28509.1 - 8e-08 32.4 1.1 2.2e-07 31.0 0.8 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N_2 PF13602.1 EPS28509.1 - 4.5e-07 30.8 0.0 9.4e-06 26.5 0.0 3.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPS28509.1 - 2.3e-06 27.3 0.9 8.4e-06 25.5 0.7 2.0 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.18 EPS28509.1 - 5.1e-05 22.3 0.1 0.00026 20.0 0.0 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.13 EPS28509.1 - 5.6e-05 22.3 0.0 0.00013 21.1 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF3237 PF11578.3 EPS28510.1 - 3.4e-36 123.8 0.0 5e-36 123.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) zf-BED PF02892.10 EPS28510.1 - 1.4e-07 31.1 2.3 0.0048 16.6 0.2 2.3 2 0 0 2 2 2 2 BED zinc finger Herpes_capsid PF06112.6 EPS28510.1 - 0.035 14.1 2.0 0.37 10.8 1.3 2.5 2 1 0 2 2 2 0 Gammaherpesvirus capsid protein zf-C2H2_2 PF12756.2 EPS28510.1 - 0.05 13.7 5.3 2.4 8.2 0.2 2.2 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Rad21_Rec8_N PF04825.8 EPS28511.1 - 8.8e-27 93.2 0.0 1.7e-26 92.3 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EPS28511.1 - 4.8e-06 25.6 0.0 1.1e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein DUF619 PF04768.8 EPS28512.1 - 1.9e-51 173.8 0.1 3.9e-51 172.8 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 EPS28512.1 - 1.3e-29 102.9 0.0 3.5e-29 101.5 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 EPS28512.1 - 9.9e-24 84.2 0.0 1.8e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.15 EPS28512.1 - 0.032 14.1 0.0 0.086 12.7 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 EPS28512.1 - 0.073 13.5 0.0 0.39 11.2 0.0 2.2 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold vATP-synt_E PF01991.13 EPS28512.1 - 0.32 10.2 0.5 20 4.3 0.0 2.5 2 0 0 2 2 2 0 ATP synthase (E/31 kDa) subunit Synaptobrevin PF00957.16 EPS28513.1 - 3.2e-34 116.3 0.9 3.7e-34 116.2 0.6 1.0 1 0 0 1 1 1 1 Synaptobrevin PRT_C PF08372.5 EPS28513.1 - 0.082 12.4 1.3 0.11 11.9 0.9 1.2 1 1 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal CDP-OH_P_transf PF01066.16 EPS28513.1 - 0.087 13.1 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 CDP-alcohol phosphatidyltransferase DUF912 PF06024.7 EPS28513.1 - 0.19 11.7 1.2 0.3 11.1 0.8 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2937 PF11157.3 EPS28513.1 - 0.29 10.4 1.3 0.37 10.0 0.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2937) Fzo_mitofusin PF04799.8 EPS28513.1 - 0.4 10.0 2.4 0.22 10.9 0.4 1.5 1 1 1 2 2 2 0 fzo-like conserved region Sel1 PF08238.7 EPS28516.1 - 6.2e-41 137.9 35.6 1.1e-06 29.0 0.0 8.1 8 0 0 8 8 8 7 Sel1 repeat TPR_6 PF13174.1 EPS28516.1 - 1.4 9.5 4.7 17 6.1 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat LigB PF02900.13 EPS28517.1 - 1.2e-48 165.4 0.0 1.4e-48 165.2 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase L51_S25_CI-B8 PF05047.11 EPS28518.1 - 3e-13 49.2 0.0 3.8e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain MPC PF03650.8 EPS28519.1 - 5.3e-44 149.0 0.4 6.9e-44 148.6 0.3 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) DUF2863 PF11062.3 EPS28519.1 - 0.0061 14.7 0.5 0.023 12.7 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2863) Metal_resist PF13801.1 EPS28519.1 - 0.11 12.5 0.7 0.66 9.9 0.0 2.0 2 0 0 2 2 2 0 Heavy-metal resistance Glyco_hydro_28 PF00295.12 EPS28520.1 - 4.5e-53 180.3 9.5 7.6e-53 179.5 6.6 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EPS28520.1 - 1.6 8.4 18.6 8.7 6.0 12.8 2.2 1 1 1 2 2 2 0 Right handed beta helix region Zn_clus PF00172.13 EPS28521.1 - 6.8e-08 32.2 5.8 6.8e-08 32.2 4.0 2.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EPS28521.1 - 3.6e-07 29.3 1.6 4.8e-07 28.9 1.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EPS28521.1 - 4.5e-05 23.5 16.3 0.009 16.3 3.4 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPS28521.1 - 0.0049 17.0 3.8 0.0049 17.0 2.7 3.6 3 1 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EPS28521.1 - 0.012 15.9 3.9 0.012 15.9 2.7 3.1 3 0 0 3 3 3 0 Zinc-finger double domain zf-met PF12874.2 EPS28521.1 - 0.25 11.6 0.1 0.25 11.6 0.1 2.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Pyr_redox_3 PF13738.1 EPS28522.1 - 1.3e-18 67.8 0.0 1.2e-16 61.3 0.0 2.4 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPS28522.1 - 5.3e-12 45.5 0.0 2.6e-11 43.3 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 EPS28522.1 - 2.2e-08 32.7 5.5 7e-08 31.1 1.2 3.2 3 1 0 3 3 3 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 EPS28522.1 - 8.6e-08 32.1 1.7 3.2e-05 23.7 0.0 3.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EPS28522.1 - 1.3e-07 31.7 0.0 3.8e-07 30.2 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EPS28522.1 - 2.5e-07 29.9 0.3 0.0013 17.7 0.1 3.2 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EPS28522.1 - 1.2e-05 24.4 0.0 0.0011 17.9 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EPS28522.1 - 0.0049 15.9 0.1 0.017 14.2 0.0 1.8 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.7 EPS28522.1 - 0.013 14.4 0.2 0.025 13.5 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein rve PF00665.21 EPS28522.1 - 0.036 14.1 0.0 6.4 6.9 0.0 2.4 2 0 0 2 2 2 0 Integrase core domain GIDA PF01134.17 EPS28522.1 - 0.082 11.7 0.4 10 4.8 0.0 2.5 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 EPS28522.1 - 0.14 10.5 0.1 0.34 9.3 0.1 1.6 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 EPS28523.1 - 3.6e-76 256.5 0.0 8.4e-75 252.0 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EPS28523.1 - 1.4e-23 83.3 0.0 2.8e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.9 EPS28523.1 - 0.036 13.9 0.0 0.67 9.7 0.0 2.4 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EPS28523.1 - 0.046 12.5 0.0 0.12 11.1 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase DAO PF01266.19 EPS28523.1 - 0.081 11.8 0.6 1.3 7.8 0.0 2.2 1 1 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 EPS28523.1 - 0.11 10.9 0.0 0.16 10.3 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Lactamase_B_2 PF12706.2 EPS28525.1 - 1.6e-23 83.2 0.0 1.9e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EPS28525.1 - 3.8e-14 52.7 0.0 5.1e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain BAALC_N PF06989.7 EPS28525.1 - 0.06 13.6 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 BAALC N-terminus EphA2_TM PF14575.1 EPS28526.1 - 0.069 13.5 0.3 0.22 11.9 0.0 1.8 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DUF912 PF06024.7 EPS28526.1 - 0.16 11.9 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) VSP PF03302.8 EPS28526.1 - 0.32 9.6 5.1 0.19 10.3 2.1 1.6 2 0 0 2 2 2 0 Giardia variant-specific surface protein DDE_1 PF03184.14 EPS28527.1 - 3.9e-44 150.3 0.0 1.7e-43 148.2 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EPS28527.1 - 9.2e-16 57.4 9.7 1.6e-14 53.4 0.3 3.4 3 0 0 3 3 3 2 Tc5 transposase DNA-binding domain Dioxygenase_C PF00775.16 EPS28528.1 - 1.5e-10 40.5 0.6 3e-10 39.6 0.0 1.9 2 1 0 2 2 2 1 Dioxygenase Sugar_tr PF00083.19 EPS28529.1 - 1.2e-123 413.0 30.4 1.4e-123 412.8 21.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS28529.1 - 1.3e-26 93.1 58.4 1.4e-23 83.1 21.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EPS28529.1 - 2.3e-06 26.2 32.9 3.6e-05 22.3 7.7 3.4 3 1 0 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 EPS28529.1 - 0.0034 15.6 0.7 0.0034 15.6 0.5 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF3154 PF11351.3 EPS28529.1 - 4 7.2 7.7 4 7.2 2.6 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3154) PEMT PF04191.8 EPS28533.1 - 3.9e-13 49.4 1.4 3.9e-13 49.4 1.0 2.5 2 1 1 3 3 3 1 Phospholipid methyltransferase ICMT PF04140.9 EPS28533.1 - 1e-10 41.6 2.2 1.2e-09 38.2 0.5 2.7 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1295 PF06966.7 EPS28533.1 - 0.017 14.4 0.2 0.023 13.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) MerC PF03203.9 EPS28533.1 - 9.7 6.5 9.3 1.5 9.2 2.9 2.1 2 0 0 2 2 2 0 MerC mercury resistance protein AA_permease_2 PF13520.1 EPS28534.1 - 7.8e-52 176.2 58.7 9.5e-52 175.9 40.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPS28534.1 - 2.1e-14 52.7 50.0 3.4e-14 52.0 34.7 1.2 1 0 0 1 1 1 1 Amino acid permease BRE PF06113.7 EPS28534.1 - 0.035 13.1 0.0 0.068 12.1 0.0 1.4 1 1 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) DUF3767 PF12597.3 EPS28534.1 - 1.8 8.2 3.5 30 4.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3767) SecE PF00584.15 EPS28534.1 - 9.7 5.8 13.6 2.8 7.5 0.4 3.6 3 0 0 3 3 3 0 SecE/Sec61-gamma subunits of protein translocation complex Amino_oxidase PF01593.19 EPS28535.1 - 1.5e-62 212.1 0.5 1.5e-51 175.8 0.2 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EPS28535.1 - 2.7e-07 30.4 0.0 6.2e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EPS28535.1 - 5.1e-05 23.4 0.1 0.00094 19.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPS28535.1 - 0.015 15.7 0.2 0.21 12.0 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPS28535.1 - 0.024 14.5 0.1 0.075 12.8 0.1 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EPS28535.1 - 0.036 13.1 0.0 0.16 10.9 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.17 EPS28535.1 - 0.051 12.4 0.0 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Shikimate_DH PF01488.15 EPS28535.1 - 0.069 13.2 0.1 0.34 11.0 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 EPS28535.1 - 0.11 11.3 0.2 0.17 10.7 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 EPS28535.1 - 0.13 11.3 0.4 0.22 10.5 0.3 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 EPS28535.1 - 0.13 11.3 0.1 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family DAO PF01266.19 EPS28535.1 - 0.65 8.8 3.2 0.33 9.8 0.1 2.0 3 0 0 3 3 3 0 FAD dependent oxidoreductase Malate_synthase PF01274.17 EPS28537.1 - 1.1e-235 782.6 0.0 1.2e-235 782.4 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Glyco_hydro_3 PF00933.16 EPS28539.1 - 4.5e-87 291.8 0.0 6.3e-87 291.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EPS28539.1 - 4.9e-54 183.2 0.0 4e-53 180.2 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EPS28539.1 - 1.2e-22 79.5 0.1 3e-22 78.3 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain ABC_tran PF00005.22 EPS28540.1 - 6.2e-47 159.3 0.0 3.1e-25 89.0 0.0 4.1 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EPS28540.1 - 8e-16 58.8 2.3 0.0036 17.3 0.0 4.2 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 EPS28540.1 - 2.7e-11 43.1 1.3 0.0062 15.7 0.0 4.4 4 1 0 4 4 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EPS28540.1 - 5.2e-07 29.0 1.6 0.022 14.3 0.4 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.1 EPS28540.1 - 3.9e-06 26.1 0.0 0.14 11.1 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain Chromo PF00385.19 EPS28540.1 - 5.3e-06 26.0 0.0 1.1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SbcCD_C PF13558.1 EPS28540.1 - 1.3e-05 25.0 0.0 0.23 11.4 0.0 3.2 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 EPS28540.1 - 2.3e-05 23.6 0.0 0.064 12.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 EPS28540.1 - 3.3e-05 24.3 3.5 0.039 14.2 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 EPS28540.1 - 3.3e-05 24.0 0.0 0.027 14.5 0.0 3.1 2 1 0 2 2 2 1 AAA domain Miro PF08477.8 EPS28540.1 - 4.4e-05 23.9 0.0 0.12 12.8 0.0 3.0 2 0 0 2 2 2 2 Miro-like protein AAA_10 PF12846.2 EPS28540.1 - 5.2e-05 22.8 0.8 1.1 8.5 0.0 4.0 4 0 0 4 4 4 2 AAA-like domain MMR_HSR1 PF01926.18 EPS28540.1 - 7.5e-05 22.6 1.0 0.54 10.2 0.0 3.3 4 0 0 4 4 2 2 50S ribosome-binding GTPase AAA_13 PF13166.1 EPS28540.1 - 0.00059 18.4 0.3 0.12 10.7 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EPS28540.1 - 0.00087 20.0 0.0 1.6 9.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EPS28540.1 - 0.0018 18.2 0.0 1.1 9.1 0.0 3.0 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EPS28540.1 - 0.0019 18.3 0.0 1.1 9.4 0.0 2.6 2 0 0 2 2 2 1 RNA helicase DUF87 PF01935.12 EPS28540.1 - 0.0023 17.7 2.6 0.23 11.2 0.1 3.2 4 0 0 4 4 3 1 Domain of unknown function DUF87 NACHT PF05729.7 EPS28540.1 - 0.0024 17.5 0.1 0.2 11.3 0.0 2.6 2 0 0 2 2 2 1 NACHT domain MobB PF03205.9 EPS28540.1 - 0.0042 16.7 0.0 2.7 7.6 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 EPS28540.1 - 0.0049 16.6 0.0 1 9.1 0.0 3.2 2 1 0 2 2 2 1 Dynamin family AAA_25 PF13481.1 EPS28540.1 - 0.01 15.2 0.0 3.8 6.8 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EPS28540.1 - 0.012 15.4 0.0 2.5 7.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EPS28540.1 - 0.02 14.3 0.3 3.2 7.1 0.1 2.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family HEAT_2 PF13646.1 EPS28540.1 - 0.021 15.0 6.3 1.1 9.5 0.2 4.1 3 2 0 3 3 2 0 HEAT repeats ArgK PF03308.11 EPS28540.1 - 0.047 12.4 0.4 4.2 6.0 0.0 2.4 2 0 0 2 2 2 0 ArgK protein AAA PF00004.24 EPS28540.1 - 0.095 12.9 0.0 3 8.0 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 EPS28540.1 - 0.1 11.4 0.2 6.4 5.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Septin PF00735.13 EPS28540.1 - 0.18 10.7 0.0 18 4.2 0.0 2.3 2 0 0 2 2 2 0 Septin DUF3584 PF12128.3 EPS28540.1 - 0.5 7.6 1.7 2.6 5.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Citrate_synt PF00285.16 EPS28541.1 - 2.1e-99 332.6 0.0 2.5e-99 332.3 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase AMP-binding PF00501.23 EPS28542.1 - 1e-75 254.7 0.0 1.2e-75 254.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPS28542.1 - 5.1e-09 36.9 0.0 1.5e-08 35.4 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain BATS PF06968.8 EPS28544.1 - 1.1e-27 95.6 0.0 6e-27 93.3 0.0 2.1 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 EPS28544.1 - 6.6e-18 65.4 0.1 3.3e-17 63.1 0.0 2.1 3 0 0 3 3 3 1 Radical SAM superfamily IGPS PF00218.16 EPS28544.1 - 0.12 11.3 0.1 0.23 10.4 0.0 1.4 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase FA_hydroxylase PF04116.8 EPS28545.1 - 1.2e-15 57.8 17.1 1.2e-15 57.8 11.9 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Tautomerase_3 PF14832.1 EPS28546.1 - 7.1e-52 175.0 0.0 8.1e-52 174.8 0.0 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Tautomerase PF01361.16 EPS28546.1 - 0.082 12.5 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Tautomerase enzyme DUF3433 PF11915.3 EPS28547.1 - 5.6e-25 87.3 15.6 3.6e-13 49.4 2.6 3.6 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) MFS_1 PF07690.11 EPS28548.1 - 4.5e-18 65.0 47.4 1.2e-09 37.3 13.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Aminotran_3 PF00202.16 EPS28549.1 - 6.3e-38 130.4 0.0 2.8e-19 69.1 0.0 2.5 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.1 EPS28549.1 - 2.2e-37 128.6 0.0 3.5e-37 127.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain CbiA PF01656.18 EPS28549.1 - 0.00016 21.1 0.1 0.00049 19.5 0.0 1.8 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain Aminotran_1_2 PF00155.16 EPS28550.1 - 4.1e-37 127.9 0.0 4.8e-37 127.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EPS28550.1 - 0.0087 14.8 0.0 0.13 11.0 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_3 PF00202.16 EPS28550.1 - 0.013 14.3 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-III Cys_Met_Meta_PP PF01053.15 EPS28550.1 - 0.029 12.6 0.0 0.04 12.1 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.15 EPS28550.1 - 0.047 12.2 0.0 0.094 11.2 0.0 1.4 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Hairy_orange PF07527.8 EPS28550.1 - 0.23 11.2 1.4 1.6 8.5 0.0 2.5 2 0 0 2 2 2 0 Hairy Orange E1-E2_ATPase PF00122.15 EPS28551.1 - 1.2e-62 211.0 0.6 2.6e-62 209.8 0.4 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EPS28551.1 - 6.5e-32 110.5 8.5 6.5e-32 110.5 5.9 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EPS28551.1 - 1.9e-28 100.3 0.0 2.7e-27 96.5 0.0 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EPS28551.1 - 1.4e-19 69.2 1.6 1.8e-19 68.9 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EPS28551.1 - 9.3e-16 57.5 0.0 1.7e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EPS28551.1 - 9e-12 45.5 0.0 3e-11 43.8 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EPS28551.1 - 0.00011 21.8 0.2 0.015 14.9 0.3 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DctM PF06808.7 EPS28551.1 - 0.0054 15.3 0.6 0.0054 15.3 0.4 2.8 3 0 0 3 3 3 1 DctM-like transporters zf-RING_2 PF13639.1 EPS28552.1 - 3.3e-10 39.6 3.4 5.9e-08 32.4 1.0 2.3 2 0 0 2 2 2 2 Ring finger domain zf-rbx1 PF12678.2 EPS28552.1 - 1.2e-08 34.9 2.3 7.6e-08 32.3 1.6 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EPS28552.1 - 1.1e-06 28.1 1.4 1.8e-05 24.2 0.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPS28552.1 - 8.8e-06 25.6 5.2 7.5e-05 22.6 0.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPS28552.1 - 9.7e-06 25.1 2.1 0.00026 20.6 0.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EPS28552.1 - 1.3e-05 24.9 0.6 3.1e-05 23.7 0.1 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EPS28552.1 - 7.8e-05 22.3 1.1 0.00059 19.5 0.1 2.2 2 0 0 2 2 2 1 zinc-RING finger domain TMEM154 PF15102.1 EPS28552.1 - 0.017 14.8 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family PHD PF00628.24 EPS28552.1 - 0.038 13.6 0.7 0.11 12.1 0.5 1.8 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.2 EPS28552.1 - 0.05 13.6 3.7 0.21 11.6 1.1 2.4 2 1 0 2 2 2 0 RING-variant domain FANCL_C PF11793.3 EPS28552.1 - 0.081 12.9 6.6 2.5 8.1 4.3 2.7 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 EPS28552.1 - 0.6 9.8 6.0 0.37 10.5 0.8 2.4 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.1 EPS28552.1 - 1 9.0 4.1 0.88 9.2 1.2 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 EPS28552.1 - 2.6 7.6 5.9 0.26 10.8 0.9 1.7 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit DUF3112 PF11309.3 EPS28553.1 - 0.069 12.9 6.1 1.4 8.6 1.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3112) AA_permease_2 PF13520.1 EPS28554.1 - 5.1e-61 206.4 46.5 6.4e-61 206.1 32.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPS28554.1 - 1.6e-25 89.3 37.8 2.2e-25 88.9 26.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF4181 PF13789.1 EPS28554.1 - 3.7 7.5 17.4 1 9.3 0.4 4.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4181) MmgE_PrpD PF03972.9 EPS28555.1 - 9.6e-152 505.2 0.0 1.1e-151 505.0 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DHC_N1 PF08385.7 EPS28555.1 - 0.049 12.0 0.1 0.073 11.4 0.1 1.1 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 DNA_methylase PF00145.12 EPS28556.1 - 1.2e-41 142.9 0.0 4.8e-28 98.2 0.0 2.3 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase GATase_2 PF00310.16 EPS28557.1 - 1.3e-21 76.7 0.0 2.2e-16 59.5 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EPS28557.1 - 2.3e-15 56.7 0.0 5.3e-15 55.5 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EPS28557.1 - 2.4e-13 49.8 0.0 9.6e-13 47.9 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 EPS28557.1 - 6.2e-13 48.5 0.3 2.1e-12 46.8 0.1 2.0 2 0 0 2 2 2 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 EPS28557.1 - 7e-06 24.9 0.0 1.3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II PRTase_2 PF15609.1 EPS28557.1 - 0.054 12.7 0.0 0.15 11.3 0.0 1.6 1 1 0 1 1 1 0 Phosphoribosyl transferase HhH-GPD PF00730.20 EPS28558.1 - 2.1e-07 31.1 0.0 4.4e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EPS28558.1 - 0.022 14.4 0.0 0.069 12.8 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif Aldedh PF00171.17 EPS28559.1 - 1.2e-118 396.4 0.0 1.6e-118 396.0 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3969 PF13108.1 EPS28559.1 - 0.092 12.4 0.0 2.2 8.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3969) ADH_N PF08240.7 EPS28562.1 - 0.0075 16.0 0.3 0.0085 15.8 0.2 1.1 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Adeno_E3_CR2 PF02439.10 EPS28562.1 - 2.9 7.4 7.8 0.89 9.1 1.8 2.4 1 1 1 2 2 2 0 Adenovirus E3 region protein CR2 FAM217 PF15344.1 EPS28563.1 - 0.14 11.7 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 FAM217 family Mt_ATP-synt_D PF05873.7 EPS28564.1 - 3.4e-18 65.8 0.8 4.1e-18 65.5 0.5 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) HlyD PF00529.15 EPS28564.1 - 0.068 12.4 5.1 0.091 12.0 3.6 1.2 1 0 0 1 1 1 0 HlyD family secretion protein Spectrin PF00435.16 EPS28564.1 - 0.2 11.9 3.1 3.6 7.9 0.6 2.2 1 1 1 2 2 2 0 Spectrin repeat Tropomyosin_1 PF12718.2 EPS28564.1 - 0.25 11.1 3.7 11 5.7 1.1 2.3 2 1 0 2 2 2 0 Tropomyosin like NAC PF01849.13 EPS28565.1 - 1e-23 82.6 0.0 1.3e-22 79.0 0.0 2.2 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 EPS28565.1 - 0.00035 20.3 0.3 0.00065 19.4 0.2 1.5 1 0 0 1 1 1 1 UBA/TS-N domain CDC45 PF02724.9 EPS28565.1 - 0.0062 14.6 3.3 0.0082 14.2 2.3 1.1 1 0 0 1 1 1 1 CDC45-like protein SpoIIIAH PF12685.2 EPS28565.1 - 3.1 7.2 10.0 0.55 9.7 4.4 1.5 2 0 0 2 2 2 0 SpoIIIAH-like protein TRAP_alpha PF03896.11 EPS28565.1 - 3.5 6.5 5.7 5.5 5.9 3.9 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Ribosomal_L14e PF01929.12 EPS28566.1 - 1.6e-24 86.0 0.1 2.5e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 EPS28566.1 - 3.4e-07 29.7 0.2 6.5e-07 28.8 0.1 1.5 1 0 0 1 1 1 1 KOW motif YIF1 PF03878.10 EPS28567.1 - 5.1e-74 248.4 4.4 6.2e-74 248.1 3.1 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 EPS28567.1 - 0.00024 20.6 5.5 0.00024 20.6 3.8 1.7 2 0 0 2 2 2 1 Yip1 domain SRP-alpha_N PF04086.8 EPS28568.1 - 4.4e-82 275.5 0.0 5.8e-82 275.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 EPS28568.1 - 4e-49 166.7 0.0 6.7e-49 166.0 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 EPS28568.1 - 3.9e-07 30.0 0.1 1.3e-06 28.4 0.0 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain ArgK PF03308.11 EPS28568.1 - 3.8e-06 25.8 0.0 7e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 ArgK protein CbiA PF01656.18 EPS28568.1 - 7.6e-06 25.4 0.1 1.5e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.1 EPS28568.1 - 0.0012 18.4 0.0 0.0023 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EPS28568.1 - 0.0056 16.1 0.1 0.052 12.9 0.0 2.2 2 0 0 2 2 2 1 AAA-like domain MobB PF03205.9 EPS28568.1 - 0.0064 16.2 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EPS28568.1 - 0.0095 15.9 0.0 0.02 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.14 EPS28568.1 - 0.042 13.0 0.0 0.071 12.3 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 EPS28568.1 - 0.07 13.0 0.0 0.24 11.3 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase Fer4_NifH PF00142.13 EPS28568.1 - 0.08 12.1 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ABC_tran PF00005.22 EPS28568.1 - 0.1 12.8 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter MFS_1 PF07690.11 EPS28570.1 - 1.1e-39 136.1 12.9 2.4e-26 92.2 3.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS28570.1 - 5.5e-15 54.8 2.7 2.3e-10 39.6 0.2 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 EPS28570.1 - 1.6e-07 30.1 9.0 0.00029 19.3 2.0 3.7 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 EPS28570.1 - 0.017 14.9 2.0 0.08 12.7 0.0 3.2 4 0 0 4 4 4 0 MFS_1 like family ATG22 PF11700.3 EPS28570.1 - 0.97 7.8 23.3 0.11 10.9 3.3 3.8 2 1 0 2 2 2 0 Vacuole effluxer Atg22 like DUF4233 PF14017.1 EPS28570.1 - 3.7 7.5 12.3 5.4 6.9 2.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4233) Acetyltransf_1 PF00583.19 EPS28572.1 - 7.9e-12 45.0 0.0 1.1e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPS28572.1 - 2.2e-11 43.7 0.0 3.1e-11 43.2 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPS28572.1 - 5.3e-10 39.4 0.0 7.9e-09 35.6 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPS28572.1 - 4.4e-09 36.2 0.0 5.7e-06 26.1 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EPS28572.1 - 0.0032 17.3 0.0 0.005 16.6 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 EPS28572.1 - 0.014 15.1 0.0 0.03 14.0 0.0 1.5 1 1 0 1 1 1 0 FR47-like protein AA_permease_2 PF13520.1 EPS28574.1 - 2.8e-46 157.9 45.9 3.4e-46 157.6 31.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPS28574.1 - 1.4e-24 86.3 40.6 2e-24 85.8 28.1 1.1 1 0 0 1 1 1 1 Amino acid permease Mpv17_PMP22 PF04117.7 EPS28576.1 - 5.9e-19 67.4 3.3 8.6e-19 66.9 0.4 2.2 2 0 0 2 2 2 1 Mpv17 / PMP22 family DUF1270 PF06900.6 EPS28576.1 - 0.52 10.4 4.1 3.7 7.7 0.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1270) RabGAP-TBC PF00566.13 EPS28577.1 - 2.4e-40 138.2 0.4 4.7e-40 137.3 0.3 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 EPS28577.1 - 1.1e-12 47.6 0.0 4.2e-05 22.9 0.0 3.5 3 0 0 3 3 3 3 Domain of unknown function (DUF3548) zf-met2 PF12907.2 EPS28578.1 - 6.6e-18 64.4 1.1 8.8e-18 64.0 0.8 1.2 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 EPS28578.1 - 1.4e-07 32.1 10.7 1.4e-07 32.1 7.4 1.5 2 0 0 2 2 2 1 4F5 protein family Myelin-PO_C PF10570.4 EPS28578.1 - 0.022 14.7 1.1 0.033 14.2 0.8 1.3 1 1 0 1 1 1 0 Myelin-PO cytoplasmic C-term p65 binding region zinc_ribbon_5 PF13719.1 EPS28578.1 - 0.07 12.7 0.2 0.1 12.1 0.1 1.3 1 0 0 1 1 1 0 zinc-ribbon domain RAMP4 PF06624.7 EPS28578.1 - 0.071 12.6 0.2 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 FAM110_N PF14161.1 EPS28578.1 - 0.072 13.3 0.2 0.082 13.1 0.1 1.2 1 0 0 1 1 1 0 Centrosome-associated N terminus zf-H2C2_2 PF13465.1 EPS28578.1 - 0.13 12.6 0.2 0.9 9.9 0.0 2.0 2 0 0 2 2 2 0 Zinc-finger double domain GAS2 PF02187.12 EPS28579.1 - 8.7e-05 22.2 0.1 0.00018 21.2 0.1 1.4 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Hexokinase_2 PF03727.11 EPS28580.1 - 1.3e-71 240.6 0.0 1.9e-71 240.1 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EPS28580.1 - 5.3e-67 225.1 0.0 9.4e-67 224.3 0.0 1.4 2 0 0 2 2 2 1 Hexokinase Tetrabrachion PF11401.3 EPS28580.1 - 0.069 12.9 1.3 1.2 8.9 0.0 2.9 3 0 0 3 3 3 0 Tetrabrachion Hus1 PF04005.7 EPS28581.1 - 1.3e-96 323.0 0.0 1.6e-96 322.7 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein Sec16_C PF12931.2 EPS28582.1 - 2.4e-105 352.3 0.1 3.3e-105 351.9 0.1 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16_N PF12935.2 EPS28582.1 - 9.2e-38 130.5 23.9 9.2e-38 130.5 16.6 4.2 4 0 0 4 4 4 1 Vesicle coat trafficking protein Sec16 N-terminus Sec16 PF12932.2 EPS28582.1 - 4.1e-32 110.6 0.0 9.1e-32 109.4 0.0 1.6 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region E1-E2_ATPase PF00122.15 EPS28583.1 - 9e-19 67.4 0.0 7.2e-18 64.4 0.0 2.5 2 2 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EPS28583.1 - 1.2e-14 55.2 0.0 9.3e-14 52.3 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EPS28583.1 - 9.6e-10 38.9 0.0 2.6e-09 37.5 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPS28583.1 - 2.7e-07 30.4 0.0 4.2e-06 26.6 0.0 2.6 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EPS28583.1 - 0.0026 17.3 0.0 0.0051 16.4 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Sugar_tr PF00083.19 EPS28584.1 - 1.1e-86 291.2 17.8 1.3e-86 290.9 12.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS28584.1 - 7.7e-28 97.2 19.6 7.7e-28 97.2 13.6 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPS28584.1 - 4.5e-06 25.1 2.8 2.5e-05 22.7 0.7 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EPS28584.1 - 0.036 12.2 3.2 0.086 10.9 1.1 1.7 1 1 1 2 2 2 0 Transmembrane secretion effector DUF4131 PF13567.1 EPS28584.1 - 0.5 9.7 7.9 0.47 9.8 0.5 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) Mso1_Sec1_bdg PF14475.1 EPS28587.1 - 1.6e-10 40.2 0.0 2.9e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Sec1-binding region of Mso1 Ribosomal_L28e PF01778.12 EPS28588.1 - 3.2e-32 111.3 1.3 6e-32 110.5 0.9 1.4 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.9 EPS28588.1 - 2.1e-26 91.9 11.0 2.1e-26 91.9 7.7 2.4 2 0 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.5 EPS28588.1 - 1.8e-07 30.6 11.3 2e-07 30.4 7.9 1.1 1 0 0 1 1 1 1 BUD22 CENP-T PF15511.1 EPS28588.1 - 0.052 12.7 14.1 0.067 12.4 9.8 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIIF_alpha PF05793.7 EPS28588.1 - 0.091 11.1 22.7 0.1 10.9 15.7 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.7 EPS28588.1 - 0.25 9.2 25.7 0.35 8.7 17.8 1.1 1 0 0 1 1 1 0 Nop14-like family DUF3402 PF11882.3 EPS28589.1 - 2.9e-160 533.8 0.0 4.2e-160 533.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 EPS28589.1 - 1e-93 313.4 0.0 1.4e-93 312.9 0.0 1.2 1 0 0 1 1 1 1 N1221-like protein PAP2 PF01569.16 EPS28590.1 - 6.3e-16 58.2 1.6 6.3e-16 58.2 1.1 2.0 1 1 1 2 2 2 1 PAP2 superfamily DUF212 PF02681.9 EPS28590.1 - 0.017 14.8 0.1 0.28 10.9 0.0 2.3 1 1 0 2 2 2 0 Divergent PAP2 family RWD PF05773.17 EPS28592.1 - 9.1e-20 70.6 0.0 1.4e-19 70.0 0.0 1.3 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 EPS28592.1 - 2.5e-18 65.7 37.5 3.6e-14 52.3 1.5 4.2 3 1 1 4 4 4 3 IBR domain zf-RING_2 PF13639.1 EPS28592.1 - 0.00077 19.2 10.7 0.00077 19.2 7.4 3.8 2 1 1 3 3 3 2 Ring finger domain Peptidase_S15 PF02129.13 EPS28593.1 - 5.5e-44 150.6 0.0 1.3e-43 149.4 0.0 1.6 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 EPS28593.1 - 4.6e-31 108.3 0.0 7.7e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_5 PF12695.2 EPS28593.1 - 0.0019 17.9 0.0 0.015 15.0 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family CRT10 PF08728.5 EPS28594.1 - 8.1e-20 70.4 0.0 2.5e-11 42.3 0.0 2.4 2 0 0 2 2 2 2 CRT10 MMtag PF10159.4 EPS28595.1 - 4.4e-33 113.1 6.4 4.4e-33 113.1 4.4 2.7 2 1 0 2 2 2 1 Kinase phosphorylation protein Glyco_hydro_63 PF03200.11 EPS28596.1 - 2.1e-240 799.8 0.0 1.8e-239 796.7 0.0 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 EPS28596.1 - 3.8e-05 22.5 0.5 6.5e-05 21.7 0.3 1.3 1 0 0 1 1 1 1 Trehalase Bac_rhamnosid PF05592.6 EPS28596.1 - 0.033 12.3 0.0 0.056 11.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase DAO PF01266.19 EPS28597.1 - 1.6e-62 211.5 0.1 2e-62 211.1 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPS28597.1 - 2e-06 27.7 0.1 4.8e-06 26.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EPS28597.1 - 2.4e-05 23.3 0.3 0.11 11.3 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.9 EPS28597.1 - 0.00018 20.2 0.3 0.018 13.7 0.1 2.0 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.22 EPS28597.1 - 0.0012 19.2 0.1 0.022 15.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPS28597.1 - 0.003 17.4 1.8 2.1 8.1 0.1 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EPS28597.1 - 0.0089 14.9 0.2 1.4 7.7 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Mqo PF06039.10 EPS28597.1 - 0.0095 14.1 0.0 0.51 8.4 0.0 2.1 2 0 0 2 2 2 1 Malate:quinone oxidoreductase (Mqo) NAD_binding_9 PF13454.1 EPS28597.1 - 0.0097 15.6 0.4 0.33 10.7 0.1 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_oxidored PF12831.2 EPS28597.1 - 0.028 13.5 1.3 0.18 10.8 0.9 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 EPS28597.1 - 0.039 13.0 0.7 0.085 11.9 0.2 1.7 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.14 EPS28597.1 - 0.049 12.6 0.0 1.5 7.8 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain GMC_oxred_N PF00732.14 EPS28597.1 - 0.068 12.3 0.1 1.6 7.8 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase DUF1777 PF08648.7 EPS28598.1 - 4.1e-26 91.8 47.9 4.1e-26 91.8 33.2 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF1777) Elong_Iki1 PF10483.4 EPS28599.1 - 2.8e-94 315.6 0.0 3.2e-94 315.4 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 Longin PF13774.1 EPS28600.1 - 7.6e-29 99.1 0.9 1.2e-28 98.4 0.6 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EPS28600.1 - 4.7e-15 54.9 0.0 9.4e-15 53.9 0.0 1.5 1 0 0 1 1 1 1 Synaptobrevin PilJ PF13675.1 EPS28600.1 - 0.1 12.9 2.9 0.62 10.3 0.2 2.2 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Syntaxin PF00804.20 EPS28600.1 - 0.2 11.8 1.5 2.9 8.1 0.1 2.1 2 0 0 2 2 2 0 Syntaxin ASXH PF13919.1 EPS28601.1 - 2e-36 124.8 1.4 2e-36 124.8 0.9 1.8 2 0 0 2 2 2 1 Asx homology domain AT_hook PF02178.14 EPS28601.1 - 0.027 14.0 3.0 0.081 12.6 2.1 1.8 1 0 0 1 1 1 0 AT hook motif adh_short PF00106.20 EPS28602.1 - 6.6e-15 55.4 0.5 1.4e-14 54.3 0.1 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPS28602.1 - 1.8e-11 44.2 0.0 3.5e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPS28602.1 - 5.7e-06 26.1 0.0 9.5e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 KR domain CLPTM1 PF05602.7 EPS28603.1 - 2.3e-172 573.6 0.0 3.1e-172 573.2 0.0 1.2 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF1240 PF06836.7 EPS28603.1 - 0.13 12.4 3.6 0.36 11.0 2.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1240) CENP-I PF07778.6 EPS28604.1 - 1.2e-90 304.2 5.0 1.6e-90 303.7 3.4 1.1 1 0 0 1 1 1 1 Mis6 Transcrip_reg PF01709.15 EPS28605.1 - 3.3e-63 212.9 0.1 3.8e-63 212.7 0.1 1.0 1 0 0 1 1 1 1 Transcriptional regulator AhpC-TSA_2 PF13911.1 EPS28605.1 - 0.084 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme HEAT PF02985.17 EPS28606.1 - 3.2e-06 26.7 12.5 8.1 6.8 0.0 9.3 9 0 0 9 9 9 4 HEAT repeat DUF1640 PF07798.6 EPS28607.1 - 1.8e-11 44.4 6.1 3.1e-11 43.6 4.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) Tyrosinase PF00264.15 EPS28608.1 - 1.5e-47 162.6 0.7 1.7e-47 162.4 0.5 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Vps51 PF08700.6 EPS28609.1 - 2.9e-14 52.6 0.0 1.2e-13 50.6 0.0 2.0 1 0 0 1 1 1 1 Vps51/Vps67 D123 PF07065.9 EPS28610.1 - 4.3e-89 298.5 0.0 5.8e-87 291.5 0.0 2.1 1 1 0 1 1 1 1 D123 DUF3627 PF12299.3 EPS28610.1 - 0.064 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3627) ECH PF00378.15 EPS28611.1 - 1.3e-27 96.4 0.0 1.6e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF2346 PF09803.4 EPS28612.1 - 0.0014 18.4 1.5 0.0022 17.8 1.1 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2346) CR6_interact PF10147.4 EPS28612.1 - 0.0019 17.5 0.9 0.0023 17.2 0.7 1.1 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF3317 PF11779.3 EPS28613.1 - 4.6e-24 83.6 3.8 4.6e-24 83.6 2.7 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3317) RF-1 PF00472.15 EPS28614.1 - 1.6e-25 89.0 2.6 2.6e-25 88.4 1.8 1.2 1 0 0 1 1 1 1 RF-1 domain CAS_CSE1 PF03378.10 EPS28615.1 - 3.7e-177 588.9 0.2 9.2e-177 587.6 0.1 1.7 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 EPS28615.1 - 3.7e-158 525.9 0.5 3.7e-158 525.9 0.4 1.7 2 0 0 2 2 2 1 Cse1 IBN_N PF03810.14 EPS28615.1 - 6.7e-16 57.9 1.4 3.3e-15 55.7 0.3 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EPS28615.1 - 0.00069 19.5 3.3 0.041 13.8 0.0 4.5 5 1 1 6 6 6 1 Exportin 1-like protein HEAT_2 PF13646.1 EPS28615.1 - 0.034 14.4 0.2 1.3 9.3 0.0 3.3 3 0 0 3 3 3 0 HEAT repeats DUF1529 PF07485.6 EPS28615.1 - 0.15 11.7 0.0 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1259) HEAT PF02985.17 EPS28615.1 - 0.18 11.9 2.1 29 5.0 0.0 5.0 4 0 0 4 4 4 0 HEAT repeat DUF3384 PF11864.3 EPS28616.1 - 4.6e-90 302.3 0.9 1e-89 301.2 0.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 EPS28616.1 - 2.7e-51 173.6 0.0 4.9e-51 172.7 0.0 1.4 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 EPS28616.1 - 2e-30 106.0 0.9 1.3e-28 100.1 0.0 2.4 2 0 0 2 2 2 2 Tuberin DUF2372 PF10178.4 EPS28617.1 - 0.015 15.4 0.0 0.024 14.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2372) HA2 PF04408.18 EPS28618.1 - 3.4e-20 71.9 0.0 1.5e-19 69.8 0.0 2.2 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EPS28618.1 - 1.4e-14 53.6 0.0 8.7e-14 51.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EPS28618.1 - 4.6e-10 39.3 0.0 1.5e-09 37.6 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EPS28618.1 - 2.5e-09 36.8 0.0 2.4e-08 33.6 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EPS28618.1 - 0.00068 19.7 0.1 0.0031 17.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EPS28618.1 - 0.0094 15.5 0.1 0.09 12.3 0.0 2.5 3 0 0 3 3 3 1 AAA domain T2SE PF00437.15 EPS28618.1 - 0.035 13.0 0.0 0.083 11.7 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.1 EPS28618.1 - 0.081 12.8 0.0 1.1 9.1 0.0 2.9 2 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EPS28618.1 - 0.085 12.5 3.1 0.85 9.2 0.0 2.7 2 0 0 2 2 2 0 Archaeal ATPase AAA_23 PF13476.1 EPS28618.1 - 0.095 13.0 0.0 0.095 13.0 0.0 4.2 4 1 0 4 4 4 0 AAA domain AAA_19 PF13245.1 EPS28618.1 - 0.13 12.0 0.0 0.99 9.2 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain ResIII PF04851.10 EPS28618.1 - 0.2 11.4 0.0 0.38 10.5 0.0 4.0 5 0 0 5 5 4 0 Type III restriction enzyme, res subunit cwf21 PF08312.7 EPS28619.1 - 3.2e-13 49.2 26.4 3.2e-13 49.2 18.3 2.7 2 1 0 2 2 2 1 cwf21 domain GvpG PF05120.7 EPS28619.1 - 0.021 14.6 0.6 0.021 14.6 0.4 2.7 3 0 0 3 3 3 0 Gas vesicle protein G Ndc1_Nup PF09531.5 EPS28619.1 - 0.33 9.3 2.4 0.39 9.0 1.6 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PUF PF00806.14 EPS28620.1 - 9.6e-61 197.9 11.0 1.4e-08 33.7 0.2 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF260 PF03195.9 EPS28620.1 - 0.087 13.1 0.4 7 6.9 0.1 3.7 2 2 0 3 3 3 0 Protein of unknown function DUF260 Phosphodiest PF01663.17 EPS28624.1 - 3.8e-13 49.4 0.3 6.6e-13 48.7 0.2 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 EPS28624.1 - 1.1e-06 28.2 0.0 2.3e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 EPS28624.1 - 0.00015 21.0 0.1 0.00028 20.1 0.1 1.4 1 0 0 1 1 1 1 Sulfatase Sugar_tr PF00083.19 EPS28625.1 - 1.7e-84 284.0 18.2 1.9e-84 283.8 12.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS28625.1 - 1.2e-18 66.9 43.3 4e-16 58.6 18.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_67M PF07488.7 EPS28626.1 - 4.1e-143 476.1 0.0 5.4e-143 475.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.7 EPS28626.1 - 5.5e-90 300.7 0.7 9.7e-90 299.8 0.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.9 EPS28626.1 - 4.4e-18 65.4 0.1 2.6e-16 59.7 0.1 2.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus DRAT PF07357.6 EPS28626.1 - 0.095 11.8 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) Glyco_hydro_30 PF02055.11 EPS28627.1 - 3e-21 75.2 1.4 4.3e-13 48.3 0.3 2.4 2 1 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 EPS28627.1 - 1.9e-12 46.7 2.2 1e-10 41.1 0.0 2.9 3 0 0 3 3 3 2 O-Glycosyl hydrolase family 30 Alpha-L-AF_C PF06964.7 EPS28627.1 - 0.0002 21.1 0.7 0.00044 20.0 0.2 1.7 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase C-terminus DUF1966 PF09260.6 EPS28627.1 - 0.082 12.9 0.3 0.32 11.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1966) Tyr-DNA_phospho PF06087.7 EPS28628.1 - 1.9e-77 260.7 0.0 2.5e-77 260.3 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 EPS28628.1 - 1.1e-06 28.4 0.0 0.014 15.0 0.0 2.5 2 0 0 2 2 2 2 PLD-like domain UIM PF02809.15 EPS28628.1 - 0.011 15.2 0.6 0.028 13.9 0.4 1.7 1 0 0 1 1 1 0 Ubiquitin interaction motif ABC2_membrane PF01061.19 EPS28629.1 - 4.6e-88 293.8 57.6 5e-48 163.0 14.1 3.4 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.22 EPS28629.1 - 1.3e-40 138.8 0.6 2.1e-21 76.6 0.0 3.0 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 EPS28629.1 - 1.7e-32 111.1 0.7 2.6e-26 91.2 0.0 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EPS28629.1 - 3.9e-08 33.2 0.1 1.6e-07 31.3 0.1 2.1 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_21 PF13304.1 EPS28629.1 - 6.2e-06 26.3 0.1 0.16 11.8 0.0 3.5 2 1 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EPS28629.1 - 7.7e-06 26.0 0.0 0.073 13.2 0.0 4.0 3 1 1 4 4 4 1 AAA domain cobW PF02492.14 EPS28629.1 - 1.6e-05 24.4 0.1 0.0003 20.2 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 EPS28629.1 - 2.1e-05 23.7 0.0 0.00076 18.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EPS28629.1 - 4.1e-05 23.0 0.0 0.31 10.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EPS28629.1 - 4.5e-05 23.3 0.3 0.01 15.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.1 EPS28629.1 - 0.0001 21.7 0.2 0.28 10.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EPS28629.1 - 0.00017 21.6 4.2 0.0034 17.4 0.0 3.1 4 0 0 4 4 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EPS28629.1 - 0.00019 21.0 0.0 0.84 9.0 0.0 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_17 PF13207.1 EPS28629.1 - 0.00025 21.8 0.0 0.009 16.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EPS28629.1 - 0.00027 20.8 0.0 0.19 11.6 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.1 EPS28629.1 - 0.0003 20.7 0.2 0.0027 17.6 0.0 2.7 3 0 0 3 3 3 1 AAA domain UPF0079 PF02367.12 EPS28629.1 - 0.00037 20.1 0.9 0.038 13.6 0.3 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 EPS28629.1 - 0.00048 20.4 0.0 0.013 15.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EPS28629.1 - 0.0021 17.7 0.1 0.16 11.6 0.1 2.5 2 0 0 2 2 2 1 NACHT domain SMC_N PF02463.14 EPS28629.1 - 0.0053 16.0 1.6 0.032 13.4 0.0 2.7 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain NB-ARC PF00931.17 EPS28629.1 - 0.0094 14.8 0.2 3.8 6.2 0.2 2.8 3 0 0 3 3 3 1 NB-ARC domain Miro PF08477.8 EPS28629.1 - 0.017 15.6 0.0 0.71 10.3 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein AAA_10 PF12846.2 EPS28629.1 - 0.019 14.3 0.6 2.9 7.2 0.1 2.4 2 0 0 2 2 2 0 AAA-like domain AAA_24 PF13479.1 EPS28629.1 - 0.022 14.3 0.2 0.53 9.8 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EPS28629.1 - 0.024 14.8 0.1 7.1 6.8 0.0 3.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EPS28629.1 - 0.047 13.4 0.6 20 5.0 0.0 3.1 3 0 0 3 3 3 0 Part of AAA domain Septin PF00735.13 EPS28629.1 - 0.051 12.5 0.1 0.25 10.3 0.1 2.0 2 0 0 2 2 2 0 Septin T2SE PF00437.15 EPS28629.1 - 0.074 11.9 0.0 3.8 6.3 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_15 PF13175.1 EPS28629.1 - 0.082 11.9 0.8 11 4.9 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain AAA_30 PF13604.1 EPS28629.1 - 0.098 12.2 2.6 2.2 7.8 0.2 3.0 3 0 0 3 3 2 0 AAA domain PduV-EutP PF10662.4 EPS28629.1 - 0.19 11.2 0.6 0.45 10.0 0.2 1.7 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation CDP-OH_P_transf PF01066.16 EPS28631.1 - 5.1e-16 58.8 4.8 1.1e-15 57.7 3.4 1.5 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase MFS_1_like PF12832.2 EPS28631.1 - 0.034 13.9 0.1 2.1 8.1 0.0 2.7 2 0 0 2 2 2 0 MFS_1 like family ABC1 PF03109.11 EPS28633.1 - 1.7e-32 111.8 0.0 4e-32 110.6 0.0 1.7 1 0 0 1 1 1 1 ABC1 family UreF PF01730.11 EPS28634.1 - 1.3e-13 51.3 0.2 3.6e-13 49.8 0.1 1.7 1 1 0 1 1 1 1 UreF Ribosomal_L29 PF00831.18 EPS28634.1 - 0.11 12.2 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 Ribosomal L29 protein BRE1 PF08647.6 EPS28635.1 - 2.8e-28 97.7 11.7 2.8e-28 97.7 8.1 7.0 4 3 2 6 6 5 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 EPS28635.1 - 1.5e-09 37.7 10.4 2.4e-09 37.0 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPS28635.1 - 5e-09 35.6 8.1 8.1e-09 35.0 5.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPS28635.1 - 4.8e-08 32.5 10.3 8.4e-08 31.7 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPS28635.1 - 2.7e-07 30.2 8.1 5.4e-07 29.3 5.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EPS28635.1 - 3.4e-06 26.6 10.7 5.7e-06 25.9 7.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EPS28635.1 - 5.2e-06 26.0 6.1 1.5e-05 24.5 4.2 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EPS28635.1 - 0.002 17.9 6.9 0.0037 17.1 4.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EPS28635.1 - 0.0028 17.7 4.2 0.011 15.8 2.4 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger Sec2p PF06428.6 EPS28635.1 - 0.003 17.3 12.9 0.003 17.3 8.9 6.2 2 2 3 6 6 5 1 GDP/GTP exchange factor Sec2p zf-RING_4 PF14570.1 EPS28635.1 - 0.017 14.7 7.3 0.084 12.4 5.4 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 EPS28635.1 - 0.02 14.4 3.9 0.042 13.3 2.7 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF1272 PF06906.6 EPS28635.1 - 0.02 14.7 5.6 0.045 13.5 3.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Reo_sigmaC PF04582.7 EPS28635.1 - 0.095 11.8 39.8 0.053 12.7 1.1 4.9 2 1 2 4 4 4 0 Reovirus sigma C capsid protein zf-RING_6 PF14835.1 EPS28635.1 - 0.17 11.7 4.4 0.32 10.8 3.0 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C2HC_2 PF13913.1 EPS28635.1 - 0.57 9.9 7.1 0.58 9.8 1.9 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Baculo_PEP_C PF04513.7 EPS28635.1 - 0.76 9.6 41.0 1.1 9.1 0.5 6.2 4 3 2 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus FYVE PF01363.16 EPS28635.1 - 1.4 8.8 12.4 26 4.8 8.7 2.4 1 1 1 2 2 2 0 FYVE zinc finger zf-Nse PF11789.3 EPS28635.1 - 1.5 8.4 9.7 0.24 10.9 4.0 1.8 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-C2H2_6 PF13912.1 EPS28635.1 - 2.1 8.3 4.6 6.6 6.7 0.4 3.0 3 0 0 3 3 2 0 C2H2-type zinc finger Filament PF00038.16 EPS28635.1 - 8.8 5.6 69.2 4.5 6.6 20.4 4.9 2 2 2 4 4 4 0 Intermediate filament protein Myb_DNA-binding PF00249.26 EPS28636.1 - 0.00024 21.0 0.0 0.001 19.0 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Phage_Gp23 PF10669.4 EPS28636.1 - 0.038 14.1 0.7 0.038 14.1 0.5 1.7 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) ATAD4 PF15321.1 EPS28636.1 - 0.82 10.7 0.0 0.82 10.7 0.0 4.6 4 0 0 4 4 4 0 ATPase family AAA domain containing 4 DUF1183 PF06682.7 EPS28637.1 - 1e-95 321.0 7.0 1.2e-95 320.8 4.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) DUF2763 PF10961.3 EPS28637.1 - 10 6.6 18.6 0.035 14.5 4.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2763) DUF2404 PF10296.4 EPS28638.1 - 0.00015 21.7 0.0 0.00026 21.0 0.0 1.4 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) ARD PF03079.9 EPS28639.1 - 9.6e-47 158.8 0.2 1.2e-46 158.5 0.1 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 EPS28639.1 - 1.2e-10 40.7 0.0 2.1e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EPS28639.1 - 1.5e-05 24.7 0.0 2.4e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EPS28639.1 - 0.0046 16.3 0.0 0.0064 15.9 0.0 1.4 1 1 0 1 1 1 1 Cupin F5_F8_type_C PF00754.20 EPS28639.1 - 0.1 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 F5/8 type C domain GIDA PF01134.17 EPS28640.1 - 1.5e-154 514.6 0.0 1.9e-154 514.2 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 EPS28640.1 - 2.3e-20 72.4 0.1 7.4e-20 70.7 0.0 1.9 1 0 0 1 1 1 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 EPS28640.1 - 5.2e-08 32.9 0.5 1.1e-07 31.9 0.3 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EPS28640.1 - 2.6e-06 26.7 1.3 4.3e-06 26.0 0.9 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 EPS28640.1 - 1.1e-05 24.5 4.8 0.0059 15.5 0.1 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPS28640.1 - 0.001 18.0 1.8 0.001 18.0 1.3 2.0 3 0 0 3 3 3 1 FAD binding domain AlaDh_PNT_C PF01262.16 EPS28640.1 - 0.011 15.2 0.8 0.02 14.4 0.5 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 EPS28640.1 - 0.026 13.0 0.7 0.24 9.8 0.4 2.1 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.9 EPS28640.1 - 0.056 12.0 0.5 7.1 5.1 0.3 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Ammonium_transp PF00909.16 EPS28641.1 - 2.6e-115 385.0 30.5 3e-115 384.8 21.1 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family E1-E2_ATPase PF00122.15 EPS28643.1 - 9.4e-81 270.2 0.3 1.5e-80 269.5 0.2 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EPS28643.1 - 8.2e-44 149.3 1.3 4.4e-43 146.9 0.0 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EPS28643.1 - 2.1e-30 106.7 0.0 7.3e-30 104.9 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EPS28643.1 - 6.5e-19 67.1 0.0 1.3e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EPS28643.1 - 6e-15 55.9 0.0 1.7e-14 54.4 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPS28643.1 - 1.3e-12 47.4 0.0 2.5e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EPS28643.1 - 4.2e-05 23.2 1.4 0.00035 20.2 0.5 2.5 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Rad21_Rec8_N PF04825.8 EPS28644.1 - 1.6e-38 131.0 0.0 2.8e-38 130.3 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EPS28644.1 - 1.4e-07 30.5 0.2 3.1e-07 29.4 0.2 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 EPS28644.1 - 0.19 11.2 0.0 0.19 11.2 0.0 2.4 3 0 0 3 3 3 0 ScpA/B protein MFS_1 PF07690.11 EPS28645.1 - 4.5e-42 144.0 35.4 5.8e-42 143.6 19.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EPS28645.1 - 3.2e-07 28.9 1.4 3.2e-07 28.9 1.0 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Bap31 PF05529.7 EPS28645.1 - 0.016 14.6 0.1 0.056 12.9 0.1 1.9 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Hexokinase_2 PF03727.11 EPS28646.1 - 1.9e-84 282.7 0.0 2.5e-84 282.3 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EPS28646.1 - 1.1e-74 250.2 0.0 1.5e-74 249.8 0.0 1.1 1 0 0 1 1 1 1 Hexokinase SIR2 PF02146.12 EPS28647.1 - 1.5e-55 187.6 0.0 2e-55 187.2 0.0 1.2 1 0 0 1 1 1 1 Sir2 family COG4 PF08318.7 EPS28648.1 - 2e-107 358.8 0.0 2.7e-107 358.3 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein TMF_TATA_bd PF12325.3 EPS28648.1 - 0.12 12.0 4.8 2.3 7.9 0.5 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Tom22 PF04281.8 EPS28649.1 - 0.14 11.6 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Gti1_Pac2 PF09729.4 EPS28657.1 - 5.2e-62 208.6 0.0 9.8e-62 207.7 0.0 1.4 2 0 0 2 2 2 1 Gti1/Pac2 family Mannosyl_trans3 PF11051.3 EPS28658.1 - 1.4e-78 264.0 0.0 7.6e-78 261.5 0.0 1.9 1 1 0 1 1 1 1 Mannosyltransferase putative YscJ_FliF_C PF08345.6 EPS28659.1 - 0.069 13.1 7.0 0.11 12.4 4.8 1.3 1 0 0 1 1 1 0 Flagellar M-ring protein C-terminal TATR PF03430.8 EPS28659.1 - 1 7.9 4.5 1.1 7.8 3.1 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Neur_chan_memb PF02932.11 EPS28659.1 - 3.8 7.3 9.4 5.1 6.9 6.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.8 EPS28659.1 - 5.3 6.8 14.3 6.4 6.5 9.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribophorin_I PF04597.9 EPS28660.1 - 1.5e-146 488.2 0.0 1.8e-146 488.1 0.0 1.0 1 0 0 1 1 1 1 Ribophorin I ICAT PF06384.6 EPS28660.1 - 0.12 12.1 0.0 0.53 10.0 0.0 2.0 2 0 0 2 2 2 0 Beta-catenin-interacting protein ICAT Indigoidine_A PF04227.7 EPS28661.1 - 7.7e-113 376.5 0.1 1.1e-112 376.0 0.1 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 EPS28661.1 - 2.3e-16 59.8 0.0 1.1e-08 34.6 0.0 2.6 2 1 0 2 2 2 2 pfkB family carbohydrate kinase DUF1138 PF06592.8 EPS28661.1 - 0.36 10.8 1.8 1.1 9.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1138) Flavokinase PF01687.12 EPS28663.1 - 4.5e-37 126.7 0.0 5.4e-37 126.4 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Zn_clus PF00172.13 EPS28664.1 - 0.0068 16.2 9.2 0.014 15.2 6.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 EPS28664.1 - 0.14 11.9 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 PAS fold Aa_trans PF01490.13 EPS28666.1 - 1.1e-73 248.1 27.7 1.2e-73 247.9 19.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PilX_N PF14341.1 EPS28666.1 - 2.5 7.8 8.3 0.11 12.2 1.1 2.3 2 0 0 2 2 2 0 PilX N-terminal EamA PF00892.15 EPS28666.1 - 5.2 7.1 19.3 5.8 6.9 2.4 3.0 2 1 0 2 2 2 0 EamA-like transporter family TatD_DNase PF01026.16 EPS28668.1 - 1.9e-51 174.7 0.0 2.4e-51 174.3 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase FMN_dh PF01070.13 EPS28669.1 - 4.3e-111 371.2 0.0 5.2e-111 370.9 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EPS28669.1 - 9e-17 60.6 0.0 1.9e-16 59.5 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EPS28669.1 - 0.00015 20.7 0.0 0.00026 20.0 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EPS28669.1 - 0.0012 17.8 0.2 0.019 13.8 0.2 2.3 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EPS28669.1 - 0.0013 17.9 0.2 0.58 9.2 0.0 2.2 1 1 1 2 2 2 2 Nitronate monooxygenase ThiG PF05690.9 EPS28669.1 - 0.051 12.6 0.0 5.1 6.0 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG SAP PF02037.22 EPS28670.1 - 1.8e-09 36.8 0.1 3e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 SAP domain Asp PF00026.18 EPS28671.1 - 4.5e-67 226.5 4.1 5.5e-67 226.2 2.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EPS28671.1 - 2.9e-10 40.3 0.4 2.9e-10 40.3 0.3 2.3 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EPS28671.1 - 0.00035 21.0 0.1 0.48 10.9 0.0 3.0 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EPS28671.1 - 0.0013 18.3 0.0 0.017 14.6 0.0 2.2 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Bac_rhamnosid PF05592.6 EPS28672.1 - 2.5e-23 82.0 0.0 3.5e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 EPS28672.1 - 4.7e-07 29.5 0.0 8.1e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain DUF608 PF04685.8 EPS28672.1 - 0.00036 19.3 0.0 0.0029 16.3 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF608 4HBT PF03061.17 EPS28673.1 - 0.00019 21.4 0.3 0.069 13.2 0.1 2.5 2 0 0 2 2 2 2 Thioesterase superfamily Methyltransf_2 PF00891.13 EPS28674.1 - 1e-23 83.7 0.0 1.6e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Rrf2 PF02082.15 EPS28674.1 - 0.026 14.6 0.0 0.064 13.3 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator MarR_2 PF12802.2 EPS28674.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 MarR family FAD_binding_3 PF01494.14 EPS28675.1 - 3.3e-09 36.2 0.0 4.4e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EPS28675.1 - 0.0033 17.4 0.1 0.0079 16.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EPS28675.1 - 0.046 12.7 0.0 0.31 10.0 0.0 2.0 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Aminotran_1_2 PF00155.16 EPS28676.1 - 9.3e-43 146.5 0.0 1.1e-42 146.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EPS28676.1 - 0.00072 18.7 0.0 0.0012 18.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_3 PF00202.16 EPS28676.1 - 0.0097 14.7 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-III p450 PF00067.17 EPS28677.1 - 5.4e-34 117.5 0.0 7e-34 117.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-C2H2_4 PF13894.1 EPS28678.1 - 1.8e-06 27.8 23.7 0.03 14.6 1.7 5.0 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2 PF00096.21 EPS28678.1 - 0.00012 22.2 26.1 0.015 15.6 1.4 4.7 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-FCS PF06467.9 EPS28678.1 - 0.012 15.2 1.9 4.1 7.1 0.2 2.8 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-H2C2_2 PF13465.1 EPS28678.1 - 0.026 14.8 0.3 0.026 14.8 0.2 3.3 3 0 0 3 3 3 0 Zinc-finger double domain zf-CHCC PF10276.4 EPS28678.1 - 0.049 13.4 4.5 3 7.7 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger domain PyrI_C PF02748.10 EPS28678.1 - 0.14 11.5 2.9 2.7 7.4 0.3 2.4 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_jaz PF12171.3 EPS28678.1 - 0.26 11.4 18.6 0.034 14.3 2.4 4.2 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding DSPc PF00782.15 EPS28680.1 - 1.2e-26 92.8 0.0 1.7e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EPS28680.1 - 0.014 14.7 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 EPS28680.1 - 0.049 12.4 0.0 0.065 12.0 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Y_phosphatase3 PF13350.1 EPS28680.1 - 0.052 13.8 0.0 0.088 13.0 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family IBR PF01485.16 EPS28680.1 - 0.98 9.3 5.3 0.73 9.7 0.1 2.7 2 1 1 3 3 3 0 IBR domain Vfa1 PF08432.5 EPS28682.1 - 2e-64 216.9 16.6 2.2e-64 216.8 11.5 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.9 EPS28682.1 - 0.0028 15.7 9.5 0.0027 15.8 6.6 1.0 1 0 0 1 1 1 1 CDC45-like protein Ycf1 PF05758.7 EPS28682.1 - 0.053 11.2 14.0 0.064 10.9 9.7 1.0 1 0 0 1 1 1 0 Ycf1 Caldesmon PF02029.10 EPS28682.1 - 0.12 10.7 21.2 0.16 10.3 14.7 1.1 1 0 0 1 1 1 0 Caldesmon Raftlin PF15250.1 EPS28682.1 - 0.18 10.2 5.9 0.22 10.0 4.1 1.1 1 0 0 1 1 1 0 Raftlin NPR3 PF03666.8 EPS28682.1 - 0.23 9.9 7.9 0.27 9.7 5.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Ctr PF04145.10 EPS28682.1 - 0.36 10.8 1.7 0.49 10.4 1.2 1.3 1 0 0 1 1 1 0 Ctr copper transporter family GAGA_bind PF06217.7 EPS28682.1 - 0.38 10.6 9.3 0.49 10.3 6.4 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family DUF1510 PF07423.6 EPS28682.1 - 0.84 8.9 20.3 1.2 8.4 14.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Presenilin PF01080.12 EPS28682.1 - 0.9 8.2 8.5 1.2 7.8 5.9 1.1 1 0 0 1 1 1 0 Presenilin DUF2201_N PF13203.1 EPS28682.1 - 0.92 8.6 6.8 1.1 8.3 4.7 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF4407 PF14362.1 EPS28682.1 - 1.2 8.0 9.6 1.5 7.7 6.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RR_TM4-6 PF06459.7 EPS28682.1 - 4.4 7.1 14.6 5.6 6.7 10.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Atrophin-1 PF03154.10 EPS28682.1 - 5.9 4.8 13.1 8.2 4.4 9.1 1.3 1 0 0 1 1 1 0 Atrophin-1 family YABBY PF04690.8 EPS28682.1 - 6.5 6.9 7.0 8.9 6.5 4.8 1.3 1 0 0 1 1 1 0 YABBY protein Ndc1_Nup PF09531.5 EPS28683.1 - 8.7e-139 463.6 0.2 3.2e-138 461.8 0.1 1.7 1 1 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Syntaxin_2 PF14523.1 EPS28684.1 - 7.7e-25 86.8 3.3 7.7e-25 86.8 2.3 2.5 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 EPS28684.1 - 1.6e-17 62.9 3.8 1.9e-17 62.6 1.4 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EPS28684.1 - 7.8e-06 25.9 0.3 7.8e-06 25.9 0.2 2.9 1 1 0 2 2 2 1 Syntaxin Synaptobrevin PF00957.16 EPS28684.1 - 0.031 13.8 2.1 0.1 12.2 1.1 2.2 2 1 0 2 2 2 0 Synaptobrevin DUF883 PF05957.8 EPS28684.1 - 0.21 11.9 0.1 0.21 11.9 0.0 3.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) AAA_13 PF13166.1 EPS28684.1 - 0.22 9.9 8.9 0.5 8.7 6.2 1.4 1 1 0 1 1 1 0 AAA domain OmpH PF03938.9 EPS28684.1 - 0.23 11.4 8.8 0.31 10.9 6.1 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.7 EPS28684.1 - 0.53 10.7 0.1 0.53 10.7 0.1 3.7 2 1 2 4 4 4 0 SlyX DUF1664 PF07889.7 EPS28684.1 - 0.77 9.5 4.3 13 5.6 0.1 2.5 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF2951 PF11166.3 EPS28684.1 - 1.2 9.0 6.3 0.84 9.5 0.2 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF2951) Cyto_heme_lyase PF01265.12 EPS28685.1 - 2.4e-77 260.0 0.2 7.8e-73 245.2 0.0 2.0 1 1 1 2 2 2 2 Cytochrome c/c1 heme lyase GHMP_kinases_N PF00288.21 EPS28686.1 - 1.6e-10 40.9 0.4 1.6e-10 40.9 0.3 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain LIF_OSM PF01291.12 EPS28686.1 - 0.059 13.3 0.4 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 LIF / OSM family DUF1772 PF08592.6 EPS28687.1 - 2e-30 105.3 6.4 2.4e-30 105.0 4.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) CbiM PF01891.11 EPS28687.1 - 0.025 14.1 4.1 0.073 12.6 2.9 1.8 1 1 0 1 1 1 0 Cobalt uptake substrate-specific transmembrane region NAD_binding_9 PF13454.1 EPS28688.1 - 7.5e-29 100.5 0.4 5.7e-26 91.1 0.0 3.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EPS28688.1 - 9.8e-12 45.3 0.0 7.3e-10 39.2 0.0 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Formyl_trans_N PF00551.14 EPS28688.1 - 1.7e-10 40.7 0.0 3.3e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase DAO PF01266.19 EPS28688.1 - 2.6e-08 33.1 0.9 0.045 12.6 0.3 3.5 3 1 1 4 4 4 3 FAD dependent oxidoreductase K_oxygenase PF13434.1 EPS28688.1 - 9.5e-07 28.0 0.0 0.007 15.3 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.19 EPS28688.1 - 7.8e-05 21.6 0.1 0.043 12.6 0.0 2.7 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.1 EPS28688.1 - 0.0014 18.6 0.2 0.021 14.8 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EPS28688.1 - 0.0059 16.5 0.0 0.13 12.1 0.0 3.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPS28688.1 - 0.13 11.3 0.3 1.7 7.6 0.0 2.4 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.9 EPS28688.1 - 0.17 10.3 0.1 3 6.2 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein MFS_1 PF07690.11 EPS28689.1 - 4e-21 75.1 62.6 6.6e-21 74.3 34.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pro-kuma_activ PF09286.6 EPS28690.1 - 3.7e-50 169.6 0.0 8.6e-50 168.4 0.0 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EPS28690.1 - 0.00014 21.1 0.1 0.00028 20.1 0.0 1.4 1 0 0 1 1 1 1 Subtilase family IKI3 PF04762.7 EPS28691.1 - 0 1115.8 0.0 0 1115.6 0.0 1.1 1 0 0 1 1 1 1 IKI3 family DUF2191 PF09957.4 EPS28691.1 - 0.81 9.5 4.0 24 4.8 0.0 4.1 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2191) TPR_1 PF00515.23 EPS28691.1 - 1 9.1 6.4 0.44 10.2 1.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EPS28691.1 - 4.5 7.4 6.1 1.7 8.7 0.7 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat COX7C PF02935.11 EPS28692.1 - 1e-15 57.2 0.7 1.1e-15 57.1 0.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc rRNA_proc-arch PF13234.1 EPS28693.1 - 4.3e-95 317.9 0.0 8.6e-95 316.9 0.0 1.5 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 EPS28693.1 - 3.2e-65 218.7 2.1 5.9e-65 217.8 1.4 1.4 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EPS28693.1 - 1.5e-21 76.6 0.1 4.5e-21 75.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPS28693.1 - 2.5e-07 30.4 0.0 5.8e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SE PF00437.15 EPS28693.1 - 0.0034 16.3 0.0 0.0082 15.0 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 EPS28693.1 - 0.021 14.6 0.0 0.13 12.0 0.0 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Cut8_C PF08559.5 EPS28694.1 - 9.8e-51 171.3 0.0 1.3e-50 170.9 0.0 1.2 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_N PF14482.1 EPS28694.1 - 3.1e-14 52.6 6.3 5.6e-14 51.8 4.4 1.4 1 0 0 1 1 1 1 Cut8 proteasome-binding domain Cut8_M PF14483.1 EPS28694.1 - 7.5e-14 51.2 1.9 1.9e-13 49.9 1.3 1.7 1 0 0 1 1 1 1 Cut8 dimerisation domain DUF3984 PF13136.1 EPS28695.1 - 3.9e-106 354.9 23.5 5.1e-106 354.5 16.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3984) Macoilin PF09726.4 EPS28695.1 - 0.89 7.7 9.4 1.1 7.4 6.5 1.1 1 0 0 1 1 1 0 Transmembrane protein OTCace_N PF02729.16 EPS28696.1 - 1.5e-43 147.8 1.3 2.7e-43 147.0 0.1 1.9 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 EPS28696.1 - 1.7e-41 141.7 0.0 2.6e-41 141.1 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain LEA_2 PF03168.8 EPS28697.1 - 2.2e-12 47.2 2.2 0.00017 21.8 0.0 4.5 4 0 0 4 4 4 3 Late embryogenesis abundant protein ALS_ss_C PF10369.4 EPS28698.1 - 8.8e-20 70.2 0.0 1.7e-18 66.0 0.0 2.4 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 EPS28698.1 - 6.4e-11 41.5 0.1 1.4e-10 40.4 0.1 1.6 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 EPS28698.1 - 8.9e-10 38.2 0.0 1.7e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 ACT domain UPF0058 PF01893.11 EPS28698.1 - 0.018 15.0 0.4 0.03 14.3 0.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0058 ACT_6 PF13740.1 EPS28698.1 - 0.023 14.4 0.1 6.1 6.6 0.0 2.6 2 0 0 2 2 2 0 ACT domain KH_1 PF00013.24 EPS28699.1 - 1.2e-10 40.8 0.0 4.3e-07 29.4 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 EPS28699.1 - 1e-05 25.0 4.2 0.00037 20.0 0.2 3.6 4 0 0 4 4 4 2 KH domain DEAD PF00270.24 EPS28700.1 - 1.9e-16 60.0 0.0 3e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPS28700.1 - 8.3e-16 57.6 0.0 1e-13 50.9 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain PPR_2 PF13041.1 EPS28701.1 - 4e-10 39.4 0.0 0.037 14.0 0.0 4.1 3 1 1 4 4 4 4 PPR repeat family PPR_3 PF13812.1 EPS28701.1 - 3.8e-09 36.0 4.4 0.013 15.7 0.0 4.8 5 0 0 5 5 5 3 Pentatricopeptide repeat domain PPR PF01535.15 EPS28701.1 - 0.0003 20.5 0.0 0.58 10.2 0.0 4.1 4 0 0 4 4 4 1 PPR repeat TPR_14 PF13428.1 EPS28701.1 - 0.038 14.6 5.6 0.3 11.8 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat MRP-S25 PF13741.1 EPS28702.1 - 3.4e-90 301.5 2.8 4e-90 301.3 2.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 SOG2 PF10428.4 EPS28703.1 - 7.4e-118 394.0 0.1 7.4e-118 394.0 0.1 2.9 4 0 0 4 4 4 1 RAM signalling pathway protein LRR_4 PF12799.2 EPS28703.1 - 1.8e-14 52.9 5.9 4.6e-06 26.1 0.2 3.5 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPS28703.1 - 2.3e-11 43.2 6.0 1.1e-06 28.2 0.6 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EPS28703.1 - 1.5e-09 36.5 5.2 0.21 11.7 0.2 6.3 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 EPS28703.1 - 4e-05 23.1 4.6 5.3 7.7 0.0 5.6 5 0 0 5 5 5 1 Leucine rich repeat LRR_6 PF13516.1 EPS28703.1 - 0.11 12.6 6.8 13 6.2 0.2 4.8 4 1 1 5 5 5 0 Leucine Rich repeat Peptidase_S10 PF00450.17 EPS28704.1 - 5.4e-63 213.5 0.0 5.2e-62 210.3 0.0 2.3 1 1 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EPS28704.1 - 2.8e-05 24.0 0.0 0.022 14.6 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family Tcp11 PF05794.8 EPS28705.1 - 2.7e-121 405.3 0.4 3.7e-121 404.9 0.3 1.1 1 0 0 1 1 1 1 T-complex protein 11 Ydc2-catalyt PF09159.5 EPS28706.1 - 1.5e-82 277.2 0.0 1.9e-82 276.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.8 EPS28706.1 - 0.00086 19.2 0.0 2.7 7.8 0.0 3.3 3 0 0 3 3 3 1 Poxvirus A22 protein SAP PF02037.22 EPS28706.1 - 0.033 13.7 0.1 0.14 11.7 0.0 2.2 2 0 0 2 2 2 0 SAP domain Glypican PF01153.14 EPS28708.1 - 7.8 4.9 6.4 5.8 5.3 3.3 1.5 1 1 1 2 2 2 0 Glypican Zn_clus PF00172.13 EPS28709.1 - 0.025 14.4 14.8 0.34 10.8 6.5 2.5 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EPS28710.1 - 8.2e-30 103.5 0.1 1.2e-29 102.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain EMP24_GP25L PF01105.19 EPS28711.1 - 2.9e-51 173.7 0.7 3.4e-51 173.5 0.5 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD HeLo PF14479.1 EPS28711.1 - 0.017 14.9 0.3 0.029 14.1 0.2 1.4 1 0 0 1 1 1 0 Prion-inhibition and propagation GCS PF03074.11 EPS28712.1 - 0.027 13.5 0.1 0.042 12.8 0.0 1.2 1 0 0 1 1 1 0 Glutamate-cysteine ligase MyTH4 PF00784.12 EPS28712.1 - 0.056 13.3 0.1 0.16 11.8 0.1 1.7 1 0 0 1 1 1 0 MyTH4 domain Meth_synt_2 PF01717.13 EPS28714.1 - 3.6e-141 469.8 0.0 2.2e-137 457.3 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EPS28714.1 - 5.6e-121 403.5 0.0 1.5e-107 359.4 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain Steroid_dh PF02544.11 EPS28715.1 - 8.2e-14 51.6 0.5 3.8e-05 23.4 0.1 3.6 3 1 0 3 3 3 3 3-oxo-5-alpha-steroid 4-dehydrogenase Ufd2P_core PF10408.4 EPS28716.1 - 2e-181 604.4 11.7 2.4e-181 604.2 8.1 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 EPS28716.1 - 5e-28 96.8 3.4 6.4e-28 96.5 0.6 2.6 2 0 0 2 2 2 1 U-box domain EF-1_beta_acid PF10587.4 EPS28716.1 - 0.0076 16.3 2.7 1.9 8.7 0.1 3.1 2 0 0 2 2 2 2 Eukaryotic elongation factor 1 beta central acidic region DUF1977 PF09320.6 EPS28717.1 - 5.2e-27 94.1 0.0 8.1e-27 93.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.26 EPS28717.1 - 2.7e-24 84.6 1.2 4.4e-24 83.9 0.9 1.4 1 0 0 1 1 1 1 DnaJ domain DUF2416 PF10315.4 EPS28718.1 - 1.7e-05 25.0 0.0 3e-05 24.2 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2416) DUF4536 PF15055.1 EPS28718.1 - 0.09 12.8 0.2 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4536) CTP_transf_2 PF01467.21 EPS28719.1 - 5.1e-06 26.6 0.0 2.3e-05 24.5 0.0 2.0 1 1 0 2 2 2 1 Cytidylyltransferase Proteasome PF00227.21 EPS28720.1 - 2.5e-41 141.0 0.0 2.9e-41 140.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit TUG-UBL1 PF11470.3 EPS28721.1 - 2.7e-25 88.0 0.1 5.9e-25 86.9 0.0 1.6 1 0 0 1 1 1 1 GLUT4 regulating protein TUG UBX PF00789.15 EPS28721.1 - 4.7e-05 23.3 0.0 0.00013 21.9 0.0 1.8 1 0 0 1 1 1 1 UBX domain Ribosomal_L36e PF01158.13 EPS28722.1 - 8.6e-38 128.2 6.8 9.9e-38 128.0 4.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e HTH_38 PF13936.1 EPS28722.1 - 0.084 12.4 0.5 1.4 8.5 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain Abi_HHR PF07815.9 EPS28722.1 - 0.71 10.0 3.4 0.29 11.2 0.5 1.8 2 1 0 2 2 2 0 Abl-interactor HHR NatB_MDM20 PF09797.4 EPS28723.1 - 1.3e-81 274.2 0.0 2.1e-81 273.5 0.0 1.4 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.1 EPS28723.1 - 8.7e-05 22.7 3.5 0.47 10.8 0.1 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EPS28723.1 - 0.26 11.9 3.1 5.1 7.8 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4363 PF14276.1 EPS28723.1 - 0.88 9.2 5.6 0.91 9.2 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4363) DUF1903 PF08991.5 EPS28724.1 - 1.3e-05 25.2 2.6 1.8e-05 24.8 1.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 EPS28724.1 - 3.5e-05 23.5 6.8 6e-05 22.8 4.7 1.4 1 0 0 1 1 1 1 CHCH domain UPF0203 PF05254.7 EPS28724.1 - 0.074 12.9 4.3 0.16 11.8 3.0 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Cmc1 PF08583.5 EPS28724.1 - 0.22 11.3 3.0 1 9.1 0.2 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 EPS28724.1 - 0.26 11.3 3.3 0.45 10.5 2.3 1.5 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 zf-RING_2 PF13639.1 EPS28725.1 - 3.8e-09 36.2 6.9 3.8e-09 36.2 4.8 2.2 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EPS28725.1 - 4.5e-09 35.8 4.2 4.5e-09 35.8 2.9 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPS28725.1 - 2.9e-08 33.5 6.9 2.9e-08 33.5 4.8 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EPS28725.1 - 2.7e-07 30.3 6.9 2.7e-07 30.3 4.8 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EPS28725.1 - 6.6e-07 28.9 3.6 6.6e-07 28.9 2.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPS28725.1 - 1.1e-06 28.2 5.6 1.1e-06 28.2 3.9 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EPS28725.1 - 1.2e-05 24.9 1.7 2.5e-05 23.9 1.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 EPS28725.1 - 0.0039 16.9 7.2 0.13 12.0 1.8 2.3 2 0 0 2 2 2 2 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EPS28725.1 - 0.004 16.9 2.4 0.004 16.9 1.7 2.2 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1470 PF07336.6 EPS28725.1 - 0.01 16.1 0.1 0.027 14.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1470) zf-rbx1 PF12678.2 EPS28725.1 - 0.017 15.1 4.0 0.017 15.1 2.8 2.5 2 1 0 2 2 2 0 RING-H2 zinc finger DZR PF12773.2 EPS28725.1 - 0.025 14.3 9.8 1.5 8.7 0.1 2.5 2 0 0 2 2 2 0 Double zinc ribbon Baculo_IE-1 PF05290.6 EPS28725.1 - 0.19 11.4 1.5 0.32 10.7 1.1 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.1 EPS28725.1 - 1.5 8.4 12.6 0.026 14.1 1.7 2.6 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zinc-ribbons_6 PF07191.7 EPS28725.1 - 9.6 6.0 9.2 3.1 7.6 0.2 2.5 2 1 0 2 2 2 0 zinc-ribbons Peptidase_S9 PF00326.16 EPS28726.1 - 7.1e-35 120.1 0.0 3.6e-34 117.8 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EPS28726.1 - 4.9e-11 42.5 0.0 9.2e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPS28726.1 - 1.7e-06 28.0 1.4 1.6e-05 24.8 1.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EPS28726.1 - 3.7e-05 23.4 0.0 8.4e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.7 EPS28726.1 - 0.00028 19.5 0.0 0.0012 17.4 0.0 2.0 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) BAAT_C PF08840.6 EPS28726.1 - 0.00058 19.6 0.0 0.011 15.4 0.0 2.3 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 EPS28726.1 - 0.0013 18.1 0.0 0.0033 16.7 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_4 PF08386.5 EPS28726.1 - 0.0017 18.2 0.1 0.0043 16.9 0.0 1.7 2 0 0 2 2 2 1 TAP-like protein LIP PF03583.9 EPS28726.1 - 0.0034 16.6 0.4 2.3 7.3 0.0 2.2 2 0 0 2 2 2 2 Secretory lipase FSH1 PF03959.8 EPS28726.1 - 0.0098 15.3 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S15 PF02129.13 EPS28726.1 - 0.011 15.1 0.1 0.53 9.6 0.2 2.4 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.15 EPS28726.1 - 0.012 15.1 0.0 5.6 6.4 0.0 2.3 1 1 0 2 2 2 0 alpha/beta hydrolase fold WD40 PF00400.27 EPS28727.1 - 5.6e-30 102.1 18.3 3.1e-08 33.2 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EPS28727.1 - 8.6e-06 24.1 0.1 1.6 6.8 0.1 3.6 2 1 2 4 4 4 3 Nucleoporin Nup120/160 Proteasome PF00227.21 EPS28728.1 - 5.8e-37 126.8 0.0 7.8e-37 126.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit UCH PF00443.24 EPS28729.1 - 4.2e-25 88.3 0.0 4e-23 81.9 0.0 2.1 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EPS28729.1 - 3.3e-12 46.3 0.2 8e-12 45.0 0.1 1.7 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EPS28729.1 - 4.2e-05 23.1 0.0 6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.27 EPS28731.1 - 7.6e-76 247.5 25.4 1.4e-08 34.3 0.0 12.7 12 1 0 12 12 12 11 WD domain, G-beta repeat Utp13 PF08625.6 EPS28731.1 - 1.2e-43 148.1 0.1 2e-43 147.4 0.0 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 EPS28731.1 - 1.1e-09 36.9 12.6 0.02 13.0 0.9 5.4 2 2 0 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EPS28731.1 - 1.1e-06 27.7 9.1 0.0012 17.6 1.8 5.8 1 1 2 4 4 4 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 EPS28731.1 - 0.014 13.7 0.1 0.027 12.7 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain DUF3312 PF11768.3 EPS28731.1 - 0.059 11.5 0.0 0.28 9.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) G-patch_2 PF12656.2 EPS28732.1 - 2.7e-28 97.6 0.8 2.1e-27 94.7 0.0 3.0 2 0 0 2 2 2 1 DExH-box splicing factor binding site G-patch PF01585.18 EPS28732.1 - 0.0032 17.2 0.2 0.0071 16.1 0.1 1.7 1 0 0 1 1 1 1 G-patch domain HSA PF07529.8 EPS28733.1 - 9.7e-20 70.1 1.9 9.7e-20 70.1 1.3 3.5 3 0 0 3 3 3 1 HSA Myb_DNA-bind_6 PF13921.1 EPS28733.1 - 1.3e-16 60.4 0.1 4.5e-16 58.7 0.1 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EPS28733.1 - 0.0039 17.1 0.1 0.0095 15.9 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain WD40 PF00400.27 EPS28734.1 - 1.8e-10 40.2 0.4 0.0048 16.7 0.0 5.4 6 0 0 6 6 6 4 WD domain, G-beta repeat MCR_beta_N PF02783.10 EPS28734.1 - 0.027 13.9 0.0 0.056 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, N-terminal domain GTP_EFTU PF00009.22 EPS28735.1 - 4.1e-37 127.4 0.0 6.6e-37 126.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EPS28735.1 - 1.8e-36 124.0 0.2 4e-36 122.9 0.2 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EPS28735.1 - 3.6e-12 46.2 0.0 7.9e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EPS28735.1 - 0.014 15.3 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Peptidase_M48 PF01435.13 EPS28736.1 - 4.4e-49 167.0 0.1 6.2e-49 166.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 EPS28736.1 - 0.0093 14.9 0.5 0.019 13.9 0.3 1.5 1 1 0 1 1 1 1 BlaR1 peptidase M56 DUF4538 PF15061.1 EPS28736.1 - 0.03 13.6 2.1 0.054 12.7 0.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) RNA_polI_A14 PF08203.6 EPS28737.1 - 8.1e-05 22.7 0.6 0.00029 21.0 0.0 2.0 2 0 0 2 2 2 1 Yeast RNA polymerase I subunit RPA14 Herpes_DNAp_acc PF04929.7 EPS28737.1 - 0.2 10.6 4.5 0.24 10.3 3.1 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF4637 PF15470.1 EPS28737.1 - 8.9 5.8 10.4 14 5.2 7.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Ribosomal_L34 PF00468.12 EPS28738.1 - 1.1e-11 44.1 13.1 1.7e-11 43.5 9.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 LAT PF15234.1 EPS28738.1 - 4.4 6.7 5.9 5.3 6.4 3.8 1.4 1 1 0 1 1 1 0 Linker for activation of T-cells Peptidase_M16_C PF05193.16 EPS28739.1 - 2.4e-20 73.0 0.0 1.1e-13 51.2 0.0 2.9 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EPS28739.1 - 4.1e-06 26.6 0.1 7e-05 22.6 0.0 2.9 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) CobT PF06213.7 EPS28739.1 - 0.00062 18.9 6.4 0.0016 17.6 4.4 1.7 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT Nop14 PF04147.7 EPS28739.1 - 0.089 10.7 10.4 0.13 10.1 7.2 1.3 1 0 0 1 1 1 0 Nop14-like family Zw10 PF06248.8 EPS28740.1 - 2.7e-14 52.2 0.6 3.4e-13 48.6 0.1 2.1 2 0 0 2 2 2 1 Centromere/kinetochore Zw10 Dsl1_C PF11989.3 EPS28740.1 - 7.9e-07 28.5 0.0 5.1e-06 25.8 0.0 2.2 2 0 0 2 2 2 1 Retrograde transport protein Dsl1 C terminal Syntaxin-6_N PF09177.6 EPS28740.1 - 0.062 13.7 2.2 1.4 9.3 0.0 3.4 2 1 0 2 2 2 0 Syntaxin 6, N-terminal NPV_P10 PF05531.7 EPS28740.1 - 0.096 12.9 0.6 13 6.1 0.0 3.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.17 EPS28740.1 - 3.3 7.7 7.9 1.5 8.8 0.3 3.4 4 0 0 4 4 4 0 Seryl-tRNA synthetase N-terminal domain WD40 PF00400.27 EPS28741.1 - 5e-35 118.1 17.3 1.9e-07 30.6 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat NLE PF08154.7 EPS28741.1 - 6.4e-23 80.5 0.2 1.2e-22 79.7 0.2 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 EPS28741.1 - 0.061 11.4 7.8 3.2 5.7 0.6 3.6 1 1 2 4 4 4 0 Nucleoporin Nup120/160 Ribosomal_S13 PF00416.17 EPS28742.1 - 2.4e-24 85.8 0.0 2.7e-24 85.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 Pro_isomerase PF00160.16 EPS28743.1 - 8.1e-47 159.3 0.6 9.8e-47 159.0 0.4 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DEAD PF00270.24 EPS28744.1 - 1.1e-46 158.3 0.0 2.7e-45 153.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPS28744.1 - 2.7e-28 97.6 0.1 5.7e-28 96.6 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EPS28744.1 - 0.022 13.5 0.0 0.03 13.1 0.0 1.1 1 0 0 1 1 1 0 SNF2 family N-terminal domain ResIII PF04851.10 EPS28744.1 - 0.057 13.2 0.0 0.14 11.9 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EPS28744.1 - 0.099 11.0 0.0 0.18 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1253) CMS1 PF14617.1 EPS28744.1 - 0.15 11.1 0.1 0.28 10.2 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Glyco_transf_28 PF03033.15 EPS28746.1 - 7.7e-22 77.5 0.0 2.3e-21 76.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EPS28746.1 - 0.00099 17.7 0.1 0.0017 17.0 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase zf-Tim10_DDP PF02953.10 EPS28746.1 - 0.14 11.4 0.1 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Tim10/DDP family zinc finger RTA1 PF04479.8 EPS28747.1 - 3.1e-42 144.5 10.9 3.1e-42 144.5 7.5 1.5 2 0 0 2 2 2 1 RTA1 like protein gpD PF02925.11 EPS28747.1 - 0.052 13.3 0.5 0.094 12.4 0.3 1.4 1 0 0 1 1 1 0 Bacteriophage scaffolding protein D Zn_clus PF00172.13 EPS28748.1 - 2.3e-09 36.9 12.1 5.4e-09 35.8 6.0 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EPS28748.1 - 1.5e-05 23.7 3.9 2e-05 23.3 2.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.8 EPS28749.1 - 5.3e-46 156.9 12.7 8.2e-46 156.3 8.8 1.2 1 0 0 1 1 1 1 RTA1 like protein gpD PF02925.11 EPS28749.1 - 0.017 14.9 0.4 0.028 14.2 0.3 1.3 1 0 0 1 1 1 0 Bacteriophage scaffolding protein D Abhydrolase_6 PF12697.2 EPS28750.1 - 2.4e-06 27.6 0.5 4.1e-06 26.8 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPS28750.1 - 2.4e-06 27.3 0.1 3.9e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EPS28750.1 - 0.00096 18.8 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein UPF0227 PF05728.7 EPS28750.1 - 0.002 17.8 0.2 0.0039 16.9 0.2 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_3 PF07859.8 EPS28750.1 - 0.0041 16.7 0.0 0.007 15.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2974 PF11187.3 EPS28750.1 - 0.0058 16.0 0.0 0.0097 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Thioesterase PF00975.15 EPS28750.1 - 0.0063 16.7 0.1 0.012 15.8 0.1 1.4 1 0 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.20 EPS28750.1 - 0.015 14.8 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_1 PF00561.15 EPS28750.1 - 0.058 12.9 0.0 0.084 12.4 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold ADH_zinc_N_2 PF13602.1 EPS28751.1 - 1.1e-12 48.9 0.1 3.4e-12 47.3 0.0 1.9 2 1 1 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPS28751.1 - 8.1e-11 41.6 0.1 1.4e-10 40.8 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPS28751.1 - 1.3e-06 28.0 0.0 2.7e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UPF0506 PF11703.3 EPS28752.1 - 0.0027 17.6 3.5 0.0027 17.6 2.4 3.6 3 1 0 3 3 3 2 UPF0506 Toxin_29 PF08116.6 EPS28752.1 - 0.0051 16.5 30.8 0.037 13.8 4.9 3.8 3 1 0 3 3 3 2 PhTx neurotoxin family Colipase PF01114.13 EPS28752.1 - 0.0059 16.0 3.1 0.0059 16.0 2.2 3.4 3 0 0 3 3 3 1 Colipase, N-terminal domain INSIG PF07281.7 EPS28754.1 - 5.5e-85 283.6 2.2 6.9e-85 283.2 1.5 1.1 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) AICARFT_IMPCHas PF01808.13 EPS28755.1 - 2e-109 365.5 0.0 2.8e-109 365.0 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 EPS28755.1 - 1.1e-25 89.3 0.0 2.9e-25 88.0 0.0 1.7 1 0 0 1 1 1 1 MGS-like domain Beta-lactamase PF00144.19 EPS28756.1 - 9.8e-36 123.4 0.0 1.6e-35 122.6 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase DEAD PF00270.24 EPS28757.1 - 2.3e-37 128.1 0.1 3.8e-37 127.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPS28757.1 - 2.1e-21 75.5 0.0 4.1e-20 71.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EPS28757.1 - 0.0006 19.5 2.7 0.011 15.5 0.8 2.9 2 1 1 3 3 3 1 Part of AAA domain ResIII PF04851.10 EPS28757.1 - 0.0018 18.1 0.0 0.0035 17.2 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 EPS28757.1 - 0.03 13.6 0.0 0.15 11.3 0.0 2.0 1 1 0 1 1 1 0 SecA DEAD-like domain UvrD-helicase PF00580.16 EPS28757.1 - 0.14 11.3 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Usp PF00582.21 EPS28760.1 - 3.2e-20 72.7 0.3 9e-20 71.2 0.0 1.9 2 0 0 2 2 2 1 Universal stress protein family MIF4G PF02854.14 EPS28761.1 - 1.1e-50 171.9 0.0 1.7e-50 171.3 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 EPS28761.1 - 4.6e-21 74.5 0.4 1.5e-20 72.8 0.3 1.9 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 TB2_DP1_HVA22 PF03134.14 EPS28763.1 - 5e-29 99.9 6.8 7.2e-29 99.3 4.7 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family NRDE PF05742.7 EPS28764.1 - 4.2e-43 147.6 0.0 7.5e-43 146.7 0.0 1.4 1 1 0 1 1 1 1 NRDE protein PP2C_C PF07830.8 EPS28764.1 - 0.0056 16.7 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein serine/threonine phosphatase 2C, C-terminal domain Cellulase PF00150.13 EPS28765.1 - 1.8e-54 184.8 2.4 2.3e-54 184.5 1.6 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 EPS28765.1 - 4.8e-14 51.7 7.3 4.8e-14 51.7 5.0 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain SSF PF00474.12 EPS28765.1 - 0.11 11.1 0.0 0.17 10.4 0.0 1.2 1 0 0 1 1 1 0 Sodium:solute symporter family Hyaluronidase_1 PF07212.6 EPS28766.1 - 0.12 11.3 0.1 0.13 11.2 0.0 1.0 1 0 0 1 1 1 0 Hyaluronidase protein (HylP) DUF1768 PF08719.6 EPS28768.1 - 2e-48 164.1 0.1 2.3e-48 163.9 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) BPL_N PF09825.4 EPS28769.1 - 7e-144 479.1 0.0 8.9e-144 478.8 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 EPS28769.1 - 2.4e-19 69.5 0.0 4.2e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family GATase_3 PF07685.9 EPS28769.1 - 0.056 13.0 0.2 0.096 12.2 0.1 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain CHCH PF06747.8 EPS28770.1 - 1.8e-07 30.8 7.7 2.8e-07 30.2 5.3 1.3 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 EPS28770.1 - 0.013 15.2 6.6 0.07 12.9 0.4 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Ndufs5 PF10200.4 EPS28770.1 - 0.043 13.7 1.8 0.06 13.3 1.2 1.2 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa COX17 PF05051.8 EPS28770.1 - 0.086 12.8 3.2 0.12 12.4 2.3 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Toxin_25 PF08095.6 EPS28770.1 - 0.19 11.5 0.4 0.19 11.5 0.3 2.0 3 0 0 3 3 3 0 Hefutoxin family Mgm101p PF06420.7 EPS28771.1 - 1e-89 298.3 0.0 1.3e-89 297.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Menin PF05053.8 EPS28771.1 - 5 5.1 6.1 6.5 4.8 4.3 1.1 1 0 0 1 1 1 0 Menin MS_channel PF00924.13 EPS28772.1 - 6.3e-19 68.1 0.3 1.1e-18 67.3 0.2 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EPS28772.1 - 0.0021 17.2 0.3 0.0052 15.9 0.2 1.8 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EPS28772.1 - 0.0077 16.3 0.1 0.018 15.1 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EPS28772.1 - 0.014 15.1 0.1 0.05 13.5 0.1 1.9 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.1 EPS28772.1 - 0.15 11.4 0.1 0.15 11.4 0.0 2.3 2 0 0 2 2 2 0 EF hand zf-RING_2 PF13639.1 EPS28776.1 - 1.5e-14 53.5 5.4 2.5e-14 52.8 3.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EPS28776.1 - 6.7e-08 32.0 3.0 1.1e-07 31.3 2.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EPS28776.1 - 1.9e-07 31.0 1.0 4.2e-07 29.9 0.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EPS28776.1 - 2.6e-06 27.3 5.1 4.7e-06 26.5 3.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPS28776.1 - 1.4e-05 24.6 1.2 2.7e-05 23.7 0.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPS28776.1 - 2.5e-05 23.9 2.1 4.5e-05 23.0 1.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EPS28776.1 - 0.00042 20.1 1.2 0.001 18.8 0.9 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EPS28776.1 - 0.0031 17.0 2.6 0.0066 16.0 1.8 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 EPS28776.1 - 0.2 11.6 2.7 0.35 10.9 1.9 1.4 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.1 EPS28776.1 - 0.39 10.6 4.7 1.2 9.1 3.4 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EPS28776.1 - 4.3 7.3 5.7 31 4.6 3.9 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain Aminotran_1_2 PF00155.16 EPS28777.1 - 2e-85 286.9 0.0 2.9e-85 286.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Syntaxin-18_N PF10496.4 EPS28778.1 - 2.2e-18 65.8 0.8 1.1e-17 63.5 0.1 2.4 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 EPS28778.1 - 3.4e-06 26.6 0.7 8.7e-06 25.3 0.5 1.7 1 0 0 1 1 1 1 SNARE domain TPR_1 PF00515.23 EPS28779.1 - 3.7e-13 48.4 2.8 3.7e-06 26.3 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EPS28779.1 - 3.8e-13 48.8 3.2 2.7e-09 36.5 0.1 3.3 1 1 2 3 3 3 2 TPR repeat TPR_2 PF07719.12 EPS28779.1 - 2.5e-12 45.7 4.1 0.00046 19.8 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EPS28779.1 - 4.6e-08 32.8 1.4 0.00021 21.1 0.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EPS28779.1 - 6.1e-08 31.9 0.0 0.0058 16.3 0.0 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EPS28779.1 - 3.1e-07 30.8 1.5 0.00049 20.7 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EPS28779.1 - 2.6e-06 26.7 0.1 5.9e-05 22.5 0.1 3.0 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.1 EPS28779.1 - 2.1e-05 24.6 0.6 2.7 8.6 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat PB1 PF00564.19 EPS28779.1 - 2.3e-05 23.9 0.0 3.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 PB1 domain TPR_9 PF13371.1 EPS28779.1 - 0.00022 21.0 0.3 0.48 10.3 0.0 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EPS28779.1 - 0.0056 16.7 0.3 0.63 10.3 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EPS28779.1 - 0.011 16.2 0.5 0.63 10.8 0.0 3.6 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 EPS28779.1 - 0.026 14.9 3.5 47 4.8 0.0 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_5 PF12688.2 EPS28779.1 - 0.052 13.5 0.0 0.094 12.7 0.0 1.4 1 0 0 1 1 1 0 Tetratrico peptide repeat TPR_10 PF13374.1 EPS28779.1 - 0.095 12.6 0.4 15 5.6 0.0 4.1 2 1 2 4 4 4 0 Tetratricopeptide repeat DUF1814 PF08843.6 EPS28780.1 - 1.2e-07 31.7 0.1 1.6e-07 31.4 0.1 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF1814) DUF2007 PF09413.5 EPS28781.1 - 0.083 12.7 0.0 0.19 11.5 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2007) Sod_Cu PF00080.15 EPS28782.1 - 9.6e-16 58.2 0.0 1.3e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.21 EPS28782.1 - 1.5e-14 53.8 0.0 3.4e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Heavy-metal-associated domain Pkinase PF00069.20 EPS28783.1 - 1.5e-62 211.1 0.0 2.3e-62 210.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS28783.1 - 3.5e-27 95.0 0.0 5.2e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EPS28783.1 - 0.013 14.5 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EPS28783.1 - 0.022 13.7 0.0 0.049 12.5 0.0 1.5 2 0 0 2 2 2 0 Kinase-like APH PF01636.18 EPS28783.1 - 0.15 11.7 0.1 0.15 11.7 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family AF-4 PF05110.8 EPS28783.1 - 0.53 8.0 10.6 0.71 7.6 7.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF3987 PF13148.1 EPS28783.1 - 2.7 6.4 7.0 3.9 5.9 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Peptidase_C14 PF00656.17 EPS28784.1 - 0.0053 16.4 0.0 0.0064 16.2 0.0 1.4 1 1 0 1 1 1 1 Caspase domain Methyltransf_28 PF02636.12 EPS28786.1 - 2.8e-79 266.0 0.0 3.5e-79 265.7 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Rhodanese PF00581.15 EPS28787.1 - 1.7e-14 54.1 0.0 2.2e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain AA_kinase PF00696.23 EPS28787.1 - 0.13 11.8 0.0 1.4 8.3 0.0 1.9 2 0 0 2 2 2 0 Amino acid kinase family Ribosomal_S21 PF01165.15 EPS28788.1 - 3.8e-08 32.6 0.7 6.7e-08 31.8 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S21 Pex14_N PF04695.8 EPS28788.1 - 0.076 13.0 9.4 0.14 12.1 6.5 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Med3 PF11593.3 EPS28788.1 - 0.15 11.3 11.3 0.2 10.8 7.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal AF-4 PF05110.8 EPS28788.1 - 0.19 9.5 17.0 0.22 9.3 11.8 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein ORC6 PF05460.8 EPS28788.1 - 0.31 10.0 10.3 0.39 9.7 7.2 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SOG2 PF10428.4 EPS28788.1 - 0.58 8.7 12.2 0.52 8.9 7.7 1.4 2 0 0 2 2 2 0 RAM signalling pathway protein TPPII_N PF12583.3 EPS28788.1 - 1.1 9.4 6.9 1.7 8.8 4.8 1.2 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal Med13_C PF06333.7 EPS28788.1 - 2 6.8 7.6 2.6 6.5 5.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal DUF605 PF04652.11 EPS28788.1 - 2.2 7.6 17.8 2.9 7.1 12.3 1.1 1 0 0 1 1 1 0 Vta1 like Herpes_capsid PF06112.6 EPS28788.1 - 6.6 6.7 18.0 13 5.7 12.5 1.6 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein PGI PF00342.14 EPS28790.1 - 8.3e-220 730.2 0.1 9.8e-220 730.0 0.1 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase PWI PF01480.12 EPS28791.1 - 5.8e-12 45.5 0.4 2.2e-11 43.6 0.4 1.9 2 0 0 2 2 2 1 PWI domain RRM_1 PF00076.17 EPS28791.1 - 0.0029 17.1 0.0 0.0078 15.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS28791.1 - 0.056 13.4 0.0 0.65 10.0 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SUKH_6 PF14568.1 EPS28791.1 - 0.14 12.6 0.0 0.4 11.1 0.0 1.8 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall LCD1 PF09798.4 EPS28791.1 - 3.8 5.3 6.0 6.4 4.6 4.1 1.3 1 0 0 1 1 1 0 DNA damage checkpoint protein MR_MLE_C PF13378.1 EPS28792.1 - 1.8e-18 66.5 0.0 9.6e-18 64.1 0.0 2.2 3 0 0 3 3 3 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EPS28792.1 - 3.6e-15 56.2 0.1 2e-14 53.8 0.0 2.2 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EPS28792.1 - 6.2e-06 26.2 0.0 1.3e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain TIM21 PF08294.6 EPS28793.1 - 2.6e-41 140.6 0.0 3.1e-41 140.3 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 EPS28793.1 - 2e-06 27.2 0.0 7e-06 25.5 0.0 1.8 1 1 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 ArfGap PF01412.13 EPS28794.1 - 4e-35 120.1 0.2 6.4e-35 119.4 0.1 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF3275 PF11679.3 EPS28794.1 - 0.037 13.6 0.2 0.037 13.6 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3275) Herpes_ICP4_N PF03584.10 EPS28794.1 - 0.059 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus ICP4-like protein N-terminal region Fungal_trans PF04082.13 EPS28795.1 - 4e-07 29.1 0.1 7.2e-07 28.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DELLA PF12041.3 EPS28795.1 - 0.1 12.2 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator DELLA protein N terminal FPN1 PF06963.7 EPS28796.1 - 2.5e-104 349.0 16.9 3.1e-104 348.7 11.7 1.1 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Kelch_3 PF13415.1 EPS28797.1 - 1.5e-31 107.8 8.0 2.8e-06 27.3 0.1 6.1 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.1 EPS28797.1 - 2.3e-27 94.4 15.6 1.2e-10 40.9 0.0 7.1 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.1 EPS28797.1 - 9e-20 69.9 3.7 0.00046 20.2 0.0 6.4 5 1 1 6 6 6 5 Kelch motif Kelch_5 PF13854.1 EPS28797.1 - 1.5e-15 56.7 0.7 0.0094 15.8 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 EPS28797.1 - 1.6e-11 43.4 9.3 0.00029 20.4 0.3 6.0 6 1 0 6 6 6 4 Kelch motif Kelch_1 PF01344.20 EPS28797.1 - 7.9e-11 41.3 9.5 0.0099 15.4 0.2 6.2 6 3 0 6 6 6 4 Kelch motif Acetyltransf_1 PF00583.19 EPS28798.1 - 0.098 12.6 0.1 0.51 10.4 0.0 2.3 2 1 0 2 2 2 0 Acetyltransferase (GNAT) family Pterin_bind PF00809.17 EPS28799.1 - 1.9e-65 220.1 0.0 3.1e-65 219.4 0.0 1.3 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 EPS28799.1 - 4.8e-41 139.4 0.0 9.5e-41 138.4 0.0 1.5 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) NMO PF03060.10 EPS28800.1 - 3e-71 240.2 2.4 3.5e-71 240.0 1.7 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EPS28800.1 - 3.6e-09 35.9 0.9 7.7e-09 34.9 0.6 1.5 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EPS28800.1 - 2.5e-07 29.8 2.8 4e-07 29.1 1.9 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EPS28800.1 - 0.0005 19.1 1.7 0.00095 18.1 1.2 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.16 EPS28800.1 - 0.01 14.8 0.7 0.019 13.9 0.5 1.5 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Transp_cyt_pur PF02133.10 EPS28801.1 - 1.3e-45 155.8 33.0 1.5e-45 155.5 22.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Cation_efflux PF01545.16 EPS28802.1 - 5.4e-74 248.8 7.2 7e-74 248.4 5.0 1.1 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 EPS28802.1 - 0.0076 15.2 14.9 0.0091 15.0 8.8 2.2 2 1 0 2 2 2 1 ZIP Zinc transporter BPD_transp_2 PF02653.11 EPS28802.1 - 0.015 14.2 0.2 0.015 14.2 0.1 2.3 2 1 0 2 2 2 0 Branched-chain amino acid transport system / permease component DUF4396 PF14342.1 EPS28803.1 - 1.6e-39 135.1 1.5 2.8e-27 95.5 0.3 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4396) HSP70 PF00012.15 EPS28805.1 - 0.0036 15.2 0.0 0.0052 14.7 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein Peptidase_M22 PF00814.20 EPS28805.1 - 0.038 13.4 0.0 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 Glycoprotease family eIF3g PF12353.3 EPS28806.1 - 1.2e-46 157.7 3.4 1.7e-46 157.2 2.3 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 EPS28806.1 - 1.5e-16 59.8 0.0 2.3e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS28806.1 - 1.4e-12 47.4 0.0 2.8e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS28806.1 - 2.1e-07 30.6 0.0 4e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2782 PF11191.3 EPS28806.1 - 0.12 12.3 0.5 0.22 11.5 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2782) NDT80_PhoG PF05224.7 EPS28808.1 - 1.5e-36 126.1 0.0 2.1e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family PROL5-SMR PF15621.1 EPS28808.1 - 1.3 9.5 13.7 1.4 9.3 1.6 3.3 3 0 0 3 3 3 0 Proline-rich submaxillary gland androgen-regulated family AMP-binding PF00501.23 EPS28811.1 - 9e-77 258.2 0.0 1.3e-76 257.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPS28811.1 - 0.00071 20.4 0.1 0.0018 19.2 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Methyltransf_16 PF10294.4 EPS28812.1 - 2.8e-09 36.6 0.0 0.00054 19.4 0.0 2.6 2 1 0 2 2 2 2 Putative methyltransferase DUF2415 PF10313.4 EPS28813.1 - 5.7e-15 54.7 0.1 2.4e-14 52.7 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) WD40 PF00400.27 EPS28813.1 - 0.16 11.9 2.9 14 5.7 0.4 3.8 3 0 0 3 3 3 0 WD domain, G-beta repeat HSP70 PF00012.15 EPS28814.1 - 1.4e-263 875.3 15.6 1.6e-263 875.1 10.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EPS28814.1 - 1.8e-14 53.1 4.6 1.8e-13 49.8 0.9 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 EPS28814.1 - 0.0034 17.0 0.0 0.01 15.4 0.0 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EPS28814.1 - 0.0067 16.2 9.7 0.54 10.0 0.3 4.4 3 2 0 3 3 3 2 Cell division protein FtsA DUF4363 PF14276.1 EPS28814.1 - 0.082 12.6 1.9 0.18 11.5 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) Hydantoinase_A PF01968.13 EPS28814.1 - 5.4 6.0 9.5 2.1 7.3 0.1 3.7 3 1 1 4 4 4 0 Hydantoinase/oxoprolinase Tom22 PF04281.8 EPS28814.1 - 6.2 6.3 11.8 0.35 10.4 3.7 2.3 1 1 1 2 2 2 0 Mitochondrial import receptor subunit Tom22 4HBT_3 PF13622.1 EPS28815.1 - 2.5 7.7 7.9 49 3.5 5.4 2.1 1 1 0 1 1 1 0 Thioesterase-like superfamily NAAA-beta PF15508.1 EPS28816.1 - 0.14 12.5 0.0 0.22 11.8 0.0 1.4 1 0 0 1 1 1 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF1682 PF07946.9 EPS28817.1 - 1.9 7.2 6.8 3.3 6.4 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Zip PF02535.17 EPS28817.1 - 3.1 6.7 11.6 0.14 11.1 3.8 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter DSHCT PF08148.7 EPS28818.1 - 1.9e-60 203.1 0.7 3.8e-60 202.1 0.5 1.5 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EPS28818.1 - 1.5e-20 73.3 0.0 3e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPS28818.1 - 1.7e-06 27.7 0.0 4.1e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPS28818.1 - 0.0078 16.0 0.1 0.087 12.6 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IBN_N PF03810.14 EPS28819.1 - 1.2e-15 57.1 0.3 1.2e-12 47.6 0.0 4.1 4 0 0 4 4 4 1 Importin-beta N-terminal domain Cse1 PF08506.5 EPS28819.1 - 8.7e-10 37.7 0.1 1.7e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Cse1 HEAT_2 PF13646.1 EPS28819.1 - 6.3e-05 23.1 0.1 0.05 13.8 0.0 3.1 2 0 0 2 2 2 2 HEAT repeats Xpo1 PF08389.7 EPS28819.1 - 0.0004 20.3 1.3 0.12 12.2 0.0 3.9 3 1 0 3 3 3 1 Exportin 1-like protein DUF2435 PF10363.4 EPS28819.1 - 0.0017 18.2 0.6 0.0074 16.1 0.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) Terpene_synth_C PF03936.11 EPS28819.1 - 0.011 14.9 0.2 0.053 12.7 0.0 2.2 2 0 0 2 2 2 0 Terpene synthase family, metal binding domain DUF4611 PF15387.1 EPS28819.1 - 0.35 11.0 10.7 0.046 13.8 0.8 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) RRM_1 PF00076.17 EPS28821.1 - 1.3e-10 40.7 0.0 2.8e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS28821.1 - 3.8e-08 33.1 0.0 7.2e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPS28821.1 - 0.00027 20.6 0.0 0.0005 19.7 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF4651 PF15513.1 EPS28821.1 - 0.11 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4651) DUF3025 PF11227.3 EPS28821.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3025) DUF2046 PF09755.4 EPS28822.1 - 0.033 13.0 1.7 0.35 9.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) bZIP_2 PF07716.10 EPS28822.1 - 0.071 12.9 7.3 0.098 12.5 0.7 2.3 2 0 0 2 2 2 0 Basic region leucine zipper Dimerisation PF08100.6 EPS28822.1 - 0.078 12.8 0.5 0.23 11.3 0.1 1.9 2 0 0 2 2 2 0 Dimerisation domain Phage_lysis PF03245.8 EPS28822.1 - 0.095 12.6 3.1 0.23 11.4 0.3 2.3 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein DivIC PF04977.10 EPS28822.1 - 0.37 10.2 3.7 1.4 8.4 0.8 2.2 2 0 0 2 2 2 0 Septum formation initiator SlyX PF04102.7 EPS28822.1 - 0.54 10.6 3.9 6.9 7.1 0.2 2.5 2 0 0 2 2 2 0 SlyX HALZ PF02183.13 EPS28822.1 - 5.6 6.7 6.3 2.9 7.6 1.4 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper CPSase_L_D2 PF02786.12 EPS28825.1 - 2.2e-107 357.1 0.0 8.5e-84 280.0 0.0 2.2 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 EPS28825.1 - 2e-41 140.5 0.0 4.9e-41 139.3 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 EPS28825.1 - 2.1e-38 131.9 0.3 1.5e-21 76.9 0.1 2.8 3 0 0 3 3 3 2 ATP-grasp domain CPSase_L_chain PF00289.17 EPS28825.1 - 9.4e-38 128.7 0.0 2.1e-17 63.1 0.0 2.6 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 EPS28825.1 - 4.8e-26 91.2 0.0 1.8e-10 40.0 0.0 3.7 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EPS28825.1 - 2.5e-17 62.7 0.0 6.5e-08 32.1 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EPS28825.1 - 3.1e-16 59.3 0.2 4.1e-08 32.8 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 EPS28825.1 - 4.5e-08 32.7 0.0 0.00053 19.5 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.1 EPS28825.1 - 0.00077 18.7 1.8 0.24 10.5 0.0 3.1 4 0 0 4 4 4 2 ATP-grasp domain GARS_A PF01071.14 EPS28825.1 - 0.0016 18.0 0.1 0.2 11.1 0.0 2.6 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Peptidase_U40 PF10464.4 EPS28825.1 - 0.023 14.1 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase U40 Epimerase PF01370.16 EPS28825.1 - 0.041 13.3 0.0 2.5 7.4 0.0 2.3 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family SET PF00856.23 EPS28826.1 - 4.2e-15 56.4 0.3 4e-14 53.2 0.0 2.6 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.13 EPS28826.1 - 1.7e-08 34.2 8.6 1.7e-08 34.2 5.9 2.0 2 0 0 2 2 2 1 MYND finger IDO PF01231.13 EPS28827.1 - 0.12 10.7 0.4 0.12 10.7 0.2 1.0 1 0 0 1 1 1 0 Indoleamine 2,3-dioxygenase AAA PF00004.24 EPS28828.1 - 1.1e-54 184.2 0.0 1.9e-43 147.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 EPS28828.1 - 4.3e-28 97.1 0.4 9.4e-28 96.0 0.2 1.6 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 EPS28828.1 - 4.2e-11 43.1 2.6 2.9e-05 24.1 0.0 3.8 2 1 1 3 3 3 2 AAA ATPase domain NACHT PF05729.7 EPS28828.1 - 1.2e-07 31.5 0.5 0.00019 21.1 0.0 3.4 3 0 0 3 3 3 1 NACHT domain AAA_2 PF07724.9 EPS28828.1 - 1.2e-07 31.7 0.0 0.0069 16.3 0.0 2.8 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 EPS28828.1 - 4.4e-07 29.5 0.1 0.0021 17.7 0.0 3.3 3 0 0 3 3 2 2 Part of AAA domain IstB_IS21 PF01695.12 EPS28828.1 - 4.3e-06 26.2 0.3 0.0086 15.5 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_17 PF13207.1 EPS28828.1 - 6.4e-06 26.9 0.0 0.12 13.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 EPS28828.1 - 2.8e-05 23.3 0.0 0.012 14.6 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EPS28828.1 - 5e-05 23.2 0.0 0.39 10.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EPS28828.1 - 0.0001 21.4 0.0 0.2 10.7 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_18 PF13238.1 EPS28828.1 - 0.00011 22.4 0.0 0.073 13.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EPS28828.1 - 0.00014 21.9 1.6 1.2 9.2 0.1 4.0 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EPS28828.1 - 0.00027 20.6 0.1 1.1 8.9 0.0 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) UPF0079 PF02367.12 EPS28828.1 - 0.00033 20.2 0.1 0.0078 15.8 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 EPS28828.1 - 0.00053 20.1 0.0 0.92 9.7 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.1 EPS28828.1 - 0.0018 17.7 4.4 1.8 7.9 0.1 4.2 2 2 0 3 3 3 1 AAA domain AAA_28 PF13521.1 EPS28828.1 - 0.0026 17.7 0.6 1 9.3 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.1 EPS28828.1 - 0.0032 17.3 0.0 0.27 11.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 EPS28828.1 - 0.0038 16.0 0.0 0.88 8.2 0.0 2.3 2 0 0 2 2 2 1 TIP49 C-terminus NTPase_1 PF03266.10 EPS28828.1 - 0.0078 15.9 0.0 0.16 11.6 0.0 2.3 2 0 0 2 2 2 1 NTPase ABC_tran PF00005.22 EPS28828.1 - 0.01 16.1 0.0 6.1 7.1 0.0 2.8 2 0 0 2 2 2 0 ABC transporter Mg_chelatase PF01078.16 EPS28828.1 - 0.014 14.5 0.2 0.68 9.0 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI KAP_NTPase PF07693.9 EPS28828.1 - 0.017 14.1 1.0 0.31 9.9 0.1 2.4 1 1 1 2 2 2 0 KAP family P-loop domain Cytidylate_kin2 PF13189.1 EPS28828.1 - 0.034 14.0 0.0 2.9 7.7 0.0 2.7 3 0 0 3 3 2 0 Cytidylate kinase-like family Sigma54_activat PF00158.21 EPS28828.1 - 0.035 13.5 0.0 2.3 7.6 0.0 2.6 3 0 0 3 3 2 0 Sigma-54 interaction domain KaiC PF06745.8 EPS28828.1 - 0.069 12.2 0.2 11 5.0 0.0 2.3 2 0 0 2 2 2 0 KaiC DUF815 PF05673.8 EPS28828.1 - 0.083 11.8 0.0 1.3 7.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DUF2075 PF09848.4 EPS28828.1 - 0.1 11.5 0.0 6.9 5.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 EPS28828.1 - 0.15 11.3 0.2 18 4.4 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein NB-ARC PF00931.17 EPS28828.1 - 0.15 10.8 0.2 6.9 5.4 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Arch_ATPase PF01637.13 EPS28828.1 - 0.31 10.7 0.5 40 3.7 0.0 3.1 2 2 2 4 4 4 0 Archaeal ATPase cobW PF02492.14 EPS28828.1 - 0.42 10.0 1.5 4 6.8 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MCM PF00493.18 EPS28829.1 - 9.9e-136 451.8 0.1 2.8e-135 450.3 0.0 1.7 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 EPS28829.1 - 1.4e-28 99.7 0.3 3.9e-28 98.3 0.2 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EPS28829.1 - 2.3e-07 30.1 0.0 1.8e-05 24.0 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EPS28829.1 - 2.3e-06 27.3 0.0 7.1e-06 25.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EPS28829.1 - 0.041 13.8 2.8 14 5.6 0.2 3.5 2 1 0 3 3 3 0 AAA ATPase domain Sigma54_activat PF00158.21 EPS28829.1 - 0.059 12.8 0.1 0.81 9.1 0.0 2.6 3 0 0 3 3 3 0 Sigma-54 interaction domain EIF_2_alpha PF07541.7 EPS28829.1 - 0.061 13.0 0.1 4.6 6.9 0.2 2.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 2 alpha subunit EGF_CA PF07645.10 EPS28830.1 - 1.2e-05 25.1 7.9 1.2e-05 25.1 5.5 2.1 2 1 0 2 2 2 1 Calcium-binding EGF domain EGF_3 PF12947.2 EPS28830.1 - 0.00064 19.6 7.8 0.0013 18.6 4.9 2.0 1 1 0 1 1 1 1 EGF domain cEGF PF12662.2 EPS28830.1 - 0.0047 16.5 0.0 0.0047 16.5 0.0 2.7 3 0 0 3 3 3 1 Complement Clr-like EGF-like EGF PF00008.22 EPS28830.1 - 0.0082 16.0 4.2 0.0082 16.0 2.9 2.1 2 1 0 2 2 2 1 EGF-like domain FXa_inhibition PF14670.1 EPS28830.1 - 0.04 14.0 6.5 0.04 14.0 4.5 2.5 2 2 0 2 2 2 0 Coagulation Factor Xa inhibitory site Carb_kinase PF01256.12 EPS28831.1 - 2.4e-54 184.2 0.4 2.8e-53 180.6 0.3 2.0 1 1 0 1 1 1 1 Carbohydrate kinase SPT2 PF08243.6 EPS28832.1 - 0.00018 21.7 19.7 0.00018 21.7 13.6 2.5 2 1 0 2 2 2 1 SPT2 chromatin protein Ribosomal_60s PF00428.14 EPS28833.1 - 1.2e-28 99.2 10.3 1.4e-28 99.0 7.2 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_S19 PF00203.16 EPS28834.1 - 4e-34 116.0 0.3 6.1e-34 115.4 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 SbcD_C PF12320.3 EPS28834.1 - 0.06 13.3 0.4 0.47 10.5 0.0 2.0 1 1 1 2 2 2 0 Type 5 capsule protein repressor C-terminal domain AMP-binding PF00501.23 EPS28835.1 - 5e-92 308.4 0.0 5.8e-92 308.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPS28835.1 - 1.4e-10 41.9 0.0 6.2e-10 39.8 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain NAD_binding_10 PF13460.1 EPS28836.1 - 2.5e-15 56.9 0.0 8.6e-15 55.2 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPS28836.1 - 6.1e-06 25.8 0.0 9.7e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_transf_4 PF13439.1 EPS28836.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.7 1 1 0 1 1 1 0 Glycosyltransferase Family 4 Aldo_ket_red PF00248.16 EPS28840.1 - 2.6e-52 177.3 0.0 3.1e-52 177.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF706 PF05153.10 EPS28841.1 - 8.6e-128 424.9 2.0 1.1e-127 424.6 1.4 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD PF01966.17 EPS28841.1 - 0.016 15.2 0.1 0.44 10.5 0.0 2.6 2 0 0 2 2 2 0 HD domain FAT PF02259.18 EPS28844.1 - 1.5e-124 415.5 1.0 1.5e-124 415.5 0.7 2.0 2 0 0 2 2 2 1 FAT domain DUF3385 PF11865.3 EPS28844.1 - 5.4e-61 205.2 2.1 4.2e-58 195.7 0.4 3.9 3 1 0 3 3 3 2 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.22 EPS28844.1 - 1.2e-57 195.0 0.4 2.4e-57 194.0 0.2 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Rapamycin_bind PF08771.6 EPS28844.1 - 7.9e-41 138.2 3.7 1.7e-40 137.1 0.2 3.5 3 0 0 3 3 3 1 Rapamycin binding domain HEAT_2 PF13646.1 EPS28844.1 - 1.8e-15 57.0 9.8 0.0075 16.5 0.0 8.4 6 2 1 7 7 7 3 HEAT repeats HEAT_EZ PF13513.1 EPS28844.1 - 1.1e-13 51.2 12.3 0.00032 21.1 0.0 11.3 10 3 6 16 16 16 3 HEAT-like repeat FATC PF02260.15 EPS28844.1 - 1.4e-13 49.9 0.6 3e-13 48.9 0.4 1.6 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 EPS28844.1 - 6.9e-10 38.1 17.8 0.35 11.0 0.0 11.5 13 0 0 13 13 13 2 HEAT repeat CLASP_N PF12348.3 EPS28844.1 - 7.1e-05 22.2 1.7 1.5 8.1 0.0 5.0 5 0 0 5 5 5 1 CLASP N terminal Epimerase PF01370.16 EPS28845.1 - 4.3e-19 68.8 0.0 6.6e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPS28845.1 - 5.5e-13 48.2 0.0 6.9e-13 47.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EPS28845.1 - 4.7e-10 39.7 0.0 1.1e-09 38.5 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EPS28845.1 - 5.5e-10 38.5 0.0 1.6e-09 37.1 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EPS28845.1 - 9.2e-06 25.6 0.0 2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EPS28845.1 - 2.6e-05 23.2 0.0 0.00015 20.7 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EPS28845.1 - 0.0019 17.4 0.1 0.0058 15.9 0.1 1.9 2 1 0 2 2 2 1 NmrA-like family KR PF08659.5 EPS28845.1 - 0.0029 17.3 0.0 0.0071 16.0 0.0 1.6 1 1 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 EPS28845.1 - 0.062 12.2 0.0 0.27 10.1 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase RmlD_sub_bind PF04321.12 EPS28845.1 - 0.086 11.7 0.1 0.72 8.6 0.1 2.3 2 1 0 2 2 2 0 RmlD substrate binding domain Mit_ribos_Mrp51 PF11709.3 EPS28846.1 - 8.4e-94 314.3 0.0 9.7e-94 314.0 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit Ribosomal_S17e PF00833.13 EPS28847.1 - 6.5e-59 197.0 1.0 8e-59 196.7 0.7 1.1 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 EPS28847.1 - 0.055 14.1 0.1 0.086 13.5 0.1 1.4 1 1 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal RPAP2_Rtr1 PF04181.8 EPS28848.1 - 2.3e-14 53.2 0.0 4.1e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family SH3_9 PF14604.1 EPS28849.1 - 3.1e-10 39.4 0.2 7.7e-10 38.2 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EPS28849.1 - 7.7e-10 38.0 1.0 1.2e-09 37.3 0.1 1.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 EPS28849.1 - 4.2e-07 29.3 0.0 8.2e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain CWC25 PF12542.3 EPS28850.1 - 1.9e-17 63.4 0.1 1.9e-17 63.4 0.0 3.3 3 1 0 3 3 3 1 Pre-mRNA splicing factor Adaptin_N PF01602.15 EPS28851.1 - 6.5e-130 433.9 9.9 8e-130 433.6 6.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EPS28851.1 - 3.3e-16 59.6 4.5 6.7e-16 58.6 0.1 2.9 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EPS28851.1 - 3.6e-16 59.2 4.0 9.8e-10 38.5 0.0 4.7 3 2 1 4 4 4 2 HEAT repeats HEAT PF02985.17 EPS28851.1 - 4e-11 42.0 6.5 0.00069 19.4 0.0 5.7 7 0 0 7 7 7 3 HEAT repeat Atx10homo_assoc PF09759.4 EPS28851.1 - 1.3e-07 31.2 0.3 0.54 10.0 0.0 4.1 4 0 0 4 4 4 3 Spinocerebellar ataxia type 10 protein domain Arm PF00514.18 EPS28851.1 - 2e-05 24.1 1.2 5.7 6.9 0.0 6.0 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 EPS28851.1 - 0.0001 21.7 1.3 0.5 9.6 0.0 3.7 3 0 0 3 3 3 2 CLASP N terminal HEAT_EZ PF13513.1 EPS28851.1 - 0.0023 18.3 10.1 0.075 13.5 0.0 6.1 6 1 1 7 7 7 2 HEAT-like repeat DNA_alkylation PF08713.6 EPS28851.1 - 0.14 11.6 0.1 1.9 7.9 0.0 2.6 2 1 1 3 3 3 0 DNA alkylation repair enzyme DUF1077 PF06417.7 EPS28852.1 - 7.7e-54 180.3 1.7 9.4e-54 180.0 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) CopD PF05425.8 EPS28852.1 - 0.017 15.3 0.5 0.024 14.8 0.3 1.2 1 0 0 1 1 1 0 Copper resistance protein D Rubella_Capsid PF05750.6 EPS28852.1 - 1.2 8.4 7.7 1.6 8.0 5.4 1.1 1 0 0 1 1 1 0 Rubella capsid protein MFS_1 PF07690.11 EPS28853.1 - 1.1e-49 169.0 22.0 1.1e-49 169.0 15.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS28853.1 - 9.4e-15 54.1 9.8 1.4e-13 50.2 2.0 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter UPF0542 PF15086.1 EPS28853.1 - 0.05 13.3 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 Aminotran_5 PF00266.14 EPS28854.1 - 4.5e-15 55.2 0.0 6.3e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EPS28854.1 - 0.0038 16.3 0.1 0.0063 15.5 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EPS28854.1 - 0.032 12.5 0.0 0.046 12.0 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.15 EPS28854.1 - 0.11 11.0 0.3 0.32 9.5 0.2 1.6 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Fe-S_biosyn PF01521.15 EPS28855.1 - 5.4e-10 39.2 0.0 5e-09 36.0 0.0 2.1 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis Paf67 PF10255.4 EPS28857.1 - 7.1e-157 522.4 0.0 8.2e-157 522.2 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 EPS28857.1 - 0.02 14.7 0.0 0.11 12.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat HNH_2 PF13391.1 EPS28858.1 - 0.00042 20.0 0.0 0.0011 18.7 0.0 1.8 1 1 0 1 1 1 1 HNH endonuclease Aminotran_4 PF01063.14 EPS28859.1 - 1.7e-21 76.7 0.0 3e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class IV AAR2 PF05282.6 EPS28860.1 - 2.1e-99 332.9 0.0 2.5e-99 332.6 0.0 1.0 1 0 0 1 1 1 1 AAR2 protein Ribosomal_S11 PF00411.14 EPS28861.1 - 1.6e-40 137.6 0.5 2.2e-40 137.2 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 DUF2252 PF10009.4 EPS28861.1 - 0.031 13.1 0.0 0.04 12.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) PDH PF02153.12 EPS28862.1 - 1.7e-13 50.0 0.0 2.3e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.10 EPS28862.1 - 5.8e-07 29.4 0.0 1.8e-06 27.8 0.0 1.8 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EPS28862.1 - 1.8e-06 28.2 0.0 4.2e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EPS28862.1 - 0.0002 20.5 0.0 0.00035 19.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 EPS28862.1 - 0.0017 17.8 0.0 0.0037 16.7 0.0 1.6 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EPS28862.1 - 0.0027 17.3 0.0 0.01 15.5 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.4 EPS28862.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Rossmann-like domain RICTOR_N PF14664.1 EPS28863.1 - 1.1e-136 455.3 0.7 6.6e-136 452.7 0.2 2.3 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 EPS28863.1 - 7.8e-89 296.5 0.5 6.5e-87 290.2 0.2 3.3 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 EPS28863.1 - 2.9e-44 149.6 0.0 4e-42 142.7 0.0 3.0 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 EPS28863.1 - 2.6e-25 88.1 1.7 1.4e-24 85.7 0.3 3.0 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 EPS28863.1 - 3.9e-12 45.7 5.7 8.1e-12 44.7 4.0 1.6 1 0 0 1 1 1 1 Hr1 repeat Uds1 PF15456.1 EPS28863.1 - 0.0014 18.6 3.8 0.0032 17.4 2.7 1.6 1 0 0 1 1 1 1 Up-regulated During Septation FAA_hydrolase_N PF09298.6 EPS28863.1 - 0.063 13.2 0.6 0.22 11.5 0.4 1.9 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal LON PF02190.11 EPS28864.1 - 2.2e-27 96.1 0.0 3.4e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain zf-RING_2 PF13639.1 EPS28864.1 - 2.4e-11 43.2 18.0 3e-08 33.3 7.1 2.6 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_2 PF13923.1 EPS28864.1 - 1.7e-10 40.7 20.0 1.8e-08 34.2 6.8 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPS28864.1 - 2.6e-10 39.8 17.3 1.1e-06 28.1 5.2 2.5 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EPS28864.1 - 6e-10 38.6 14.5 3.9e-09 36.0 4.3 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPS28864.1 - 6.8e-09 35.2 16.7 1.5e-07 30.9 6.1 2.5 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EPS28864.1 - 8.8e-09 35.1 18.5 6.8e-06 25.8 4.5 2.9 2 1 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EPS28864.1 - 6.2e-06 25.8 13.9 0.0018 17.9 3.2 3.0 2 1 0 2 2 2 2 RING-type zinc-finger zf-RING_4 PF14570.1 EPS28864.1 - 0.00022 20.7 7.4 0.003 17.1 3.8 2.7 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-P11 PF03854.9 EPS28864.1 - 0.0018 17.7 3.7 0.0018 17.7 2.6 2.9 4 0 0 4 4 4 1 P-11 zinc finger U-box PF04564.10 EPS28864.1 - 0.0068 16.3 0.0 0.024 14.5 0.0 1.9 1 0 0 1 1 1 1 U-box domain zf-rbx1 PF12678.2 EPS28864.1 - 0.012 15.6 3.9 0.029 14.4 2.7 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger Prok-RING_4 PF14447.1 EPS28864.1 - 7.3 6.2 14.4 11 5.6 1.2 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DZR PF12773.2 EPS28864.1 - 7.9 6.3 13.8 13 5.7 4.1 3.0 2 1 0 2 2 2 0 Double zinc ribbon Metallophos_2 PF12850.2 EPS28866.1 - 2.9e-10 40.2 0.1 4.5e-10 39.5 0.1 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EPS28866.1 - 3.5e-09 36.3 0.4 2.9e-08 33.3 0.3 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase BNIP3 PF06553.7 EPS28866.1 - 0.037 13.4 0.1 0.35 10.2 0.0 2.0 2 0 0 2 2 2 0 BNIP3 FBPase_2 PF06874.6 EPS28866.1 - 0.051 11.6 0.0 0.066 11.2 0.0 1.1 1 0 0 1 1 1 0 Firmicute fructose-1,6-bisphosphatase Rad9 PF04139.8 EPS28867.1 - 1.1e-59 201.6 1.1 1.3e-59 201.3 0.7 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.11 EPS28867.1 - 0.00021 20.1 0.8 0.0058 15.4 0.6 2.7 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 RCC1 PF00415.13 EPS28868.1 - 2.9e-31 107.4 16.9 8.6e-10 38.6 0.0 7.3 6 2 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EPS28868.1 - 1.5e-19 69.0 21.3 4.2e-06 26.2 0.0 5.8 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat Abhydrolase_4 PF08386.5 EPS28869.1 - 2.4e-14 53.0 0.0 3.3e-13 49.3 0.0 2.6 3 0 0 3 3 3 1 TAP-like protein Abhydrolase_6 PF12697.2 EPS28869.1 - 1.6e-10 41.2 2.8 3.5e-10 40.1 2.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPS28869.1 - 6.1e-09 35.7 0.0 1.8e-08 34.2 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPS28869.1 - 0.007 16.1 0.0 0.025 14.3 0.0 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Sugar_tr PF00083.19 EPS28870.1 - 1.6e-21 76.4 21.5 1.7e-19 69.7 14.9 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2333 PF10095.4 EPS28870.1 - 0.037 12.6 0.0 0.076 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) SUR7 PF06687.7 EPS28873.1 - 4.9e-20 72.0 0.6 5.9e-20 71.7 0.4 1.0 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 EPS28873.1 - 0.88 9.4 7.0 1.8 8.4 4.9 1.5 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 Mannitol_dh_C PF08125.8 EPS28875.1 - 3.7e-48 163.8 0.0 6.3e-48 163.0 0.0 1.4 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 EPS28875.1 - 8.9e-20 71.1 0.9 1.4e-19 70.4 0.2 1.7 2 0 0 2 2 2 1 Mannitol dehydrogenase Rossmann domain 3HCDH_N PF02737.13 EPS28875.1 - 0.00038 20.1 0.1 0.00088 18.9 0.1 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EPS28875.1 - 0.0026 17.1 0.4 0.0052 16.1 0.3 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 EPS28875.1 - 0.032 14.2 1.6 3.3 7.7 0.3 3.8 3 1 0 3 3 3 0 TrkA-N domain DUF1993 PF09351.5 EPS28877.1 - 1.3e-36 125.9 0.8 1.5e-36 125.7 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) Med29 PF11568.3 EPS28877.1 - 0.0051 16.8 0.1 0.0071 16.4 0.1 1.2 1 0 0 1 1 1 1 Mediator complex subunit 29 FCD PF07729.7 EPS28877.1 - 0.026 14.8 0.7 0.037 14.3 0.5 1.2 1 0 0 1 1 1 0 FCD domain HPPK PF01288.15 EPS28877.1 - 0.04 13.6 0.3 0.069 12.8 0.1 1.5 2 0 0 2 2 2 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) PHAT PF09246.5 EPS28877.1 - 0.12 12.0 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 PHAT ECH PF00378.15 EPS28878.1 - 4.5e-48 163.5 0.0 5.6e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family SWIRM PF04433.12 EPS28879.1 - 2.7e-15 56.2 0.0 8.3e-15 54.6 0.0 1.9 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.12 EPS28879.1 - 4.4e-10 38.9 5.7 7.7e-10 38.1 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 EPS28879.1 - 6.5e-08 32.5 0.0 2.3e-07 30.7 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Vasohibin PF14822.1 EPS28879.1 - 0.11 11.5 0.1 0.2 10.7 0.1 1.4 1 0 0 1 1 1 0 Vasohibin Pkinase PF00069.20 EPS28880.1 - 1.2e-71 240.9 0.0 1.5e-71 240.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS28880.1 - 4.7e-33 114.3 0.0 6.6e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EPS28880.1 - 3.5e-09 37.0 0.3 1.4e-08 35.1 0.2 2.1 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EPS28880.1 - 0.00029 19.9 0.0 0.00051 19.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Coatomer_WDAD PF04053.9 EPS28881.1 - 4.1e-169 563.0 0.0 1.8e-168 560.9 0.0 1.9 2 1 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 EPS28881.1 - 7.2e-48 158.8 9.4 2.5e-10 39.8 0.1 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 EPS28881.1 - 4.1e-06 25.2 0.1 0.026 12.6 0.0 3.6 3 0 0 3 3 3 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EPS28881.1 - 0.00074 19.2 0.0 4.8 6.9 0.0 4.0 1 1 3 4 4 4 2 Ciliary BBSome complex subunit 2, middle region ETC_C1_NDUFA5 PF04716.9 EPS28882.1 - 7.7e-24 82.9 0.6 4.4e-23 80.5 0.1 2.4 2 0 0 2 2 2 1 ETC complex I subunit conserved region Ku_PK_bind PF08785.6 EPS28882.1 - 0.1 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Ku C terminal domain like Thioredoxin PF00085.15 EPS28883.1 - 1.4e-42 143.5 0.0 1.7e-25 88.6 0.0 4.2 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.1 EPS28883.1 - 5.1e-13 49.2 0.0 3.7e-05 23.5 0.0 4.7 3 1 2 5 5 5 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EPS28883.1 - 8.3e-09 35.6 0.3 0.037 14.2 0.1 4.3 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EPS28883.1 - 5e-06 26.5 0.2 0.029 14.4 0.0 4.6 4 2 1 5 5 5 1 Thioredoxin-like HyaE PF07449.6 EPS28883.1 - 0.0001 22.1 0.0 0.31 10.9 0.0 2.8 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.16 EPS28883.1 - 0.0088 15.7 0.3 0.35 10.5 0.0 3.0 3 0 0 3 3 3 1 AhpC/TSA family Thioredoxin_7 PF13899.1 EPS28883.1 - 0.018 15.0 1.2 0.17 11.9 0.1 3.0 4 0 0 4 4 4 0 Thioredoxin-like Thioredoxin_3 PF13192.1 EPS28883.1 - 0.039 13.7 0.2 3.1 7.6 0.0 2.7 2 0 0 2 2 2 0 Thioredoxin domain QCR10 PF09796.4 EPS28884.1 - 1.9e-20 72.2 0.1 2.8e-20 71.7 0.1 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) AA_permease_2 PF13520.1 EPS28885.1 - 9.7e-63 212.1 45.3 1.3e-62 211.7 31.4 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPS28885.1 - 4.7e-15 54.9 38.1 6.3e-15 54.4 26.4 1.1 1 0 0 1 1 1 1 Amino acid permease zf-H2C2_2 PF13465.1 EPS28888.1 - 3.7e-07 30.1 12.4 1e-05 25.5 1.1 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EPS28888.1 - 2.7e-06 27.2 13.9 0.00019 21.5 4.3 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 EPS28888.1 - 0.00065 19.7 4.9 0.0011 19.0 3.4 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 EPS28888.1 - 0.0033 17.6 16.8 0.018 15.3 4.6 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EPS28888.1 - 0.0042 17.1 4.7 0.059 13.5 0.7 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Zn_Tnp_IS1595 PF12760.2 EPS28888.1 - 0.17 11.7 1.4 0.29 10.9 1.0 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-BED PF02892.10 EPS28888.1 - 0.48 10.2 8.4 0.25 11.1 0.9 2.4 2 0 0 2 2 2 0 BED zinc finger zf-met PF12874.2 EPS28888.1 - 0.6 10.3 5.3 1.8 8.8 0.6 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 EPS28888.1 - 5.6 6.7 8.4 8.9 6.1 0.7 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type CytochromB561_N PF09786.4 EPS28891.1 - 8.2 4.7 14.8 11 4.3 10.2 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal PAD_porph PF04371.10 EPS28892.1 - 3.6e-68 230.0 0.0 1.1e-67 228.3 0.0 1.7 1 1 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase DUF2007 PF09413.5 EPS28892.1 - 0.13 12.1 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2007) Amidinotransf PF02274.12 EPS28892.1 - 0.15 11.1 0.0 0.41 9.6 0.0 1.7 1 1 0 1 1 1 0 Amidinotransferase APH PF01636.18 EPS28894.1 - 9.9e-08 32.0 0.7 1.2e-07 31.7 0.5 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPS28894.1 - 0.00015 21.4 0.0 0.00016 21.2 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 EPS28894.1 - 0.048 12.7 0.0 0.059 12.4 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase Uricase PF01014.13 EPS28895.1 - 3.7e-87 289.4 4.0 1.8e-48 164.1 0.8 2.0 2 0 0 2 2 2 2 Uricase Mob_Pre PF01076.14 EPS28895.1 - 0.023 14.3 1.0 0.055 13.1 0.0 2.0 2 0 0 2 2 2 0 Plasmid recombination enzyme Ribosomal_L13 PF00572.13 EPS28896.1 - 2.6e-40 137.4 0.0 3.3e-40 137.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 Ribosomal_S9 PF00380.14 EPS28897.1 - 1.6e-40 138.1 1.0 1.8e-40 137.9 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DNA_pol_B PF00136.16 EPS28898.1 - 1.7e-114 383.1 1.1 1.7e-114 383.1 0.7 1.6 2 0 0 2 2 2 1 DNA polymerase family B zf-DNA_Pol PF08996.5 EPS28898.1 - 2.3e-66 222.7 0.4 4.1e-66 221.9 0.3 1.4 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 EPS28898.1 - 2.2e-37 128.6 0.0 4.7e-37 127.5 0.0 1.5 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 EPS28898.1 - 2.2e-24 85.0 13.2 1.1e-23 82.7 5.0 3.1 2 0 0 2 2 2 2 DNA polymerase alpha subunit p180 N terminal MFS_1 PF07690.11 EPS28899.1 - 4.6e-41 140.6 41.2 3.6e-31 108.1 27.7 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily ApbA PF02558.11 EPS28900.1 - 1.2e-25 89.7 0.0 1.6e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EPS28900.1 - 5e-25 87.9 0.0 7.4e-25 87.3 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Saccharop_dh PF03435.13 EPS28900.1 - 0.00046 19.2 0.1 0.00075 18.5 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase gp37_C PF12604.3 EPS28900.1 - 0.11 12.3 0.1 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Tail fiber protein gp37 C terminal Phos_pyr_kin PF08543.7 EPS28901.1 - 6.9e-81 271.0 0.5 9e-81 270.6 0.4 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 EPS28901.1 - 3e-52 177.4 0.1 4.2e-52 176.9 0.1 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 EPS28901.1 - 1.5e-06 27.5 0.1 2.6e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Carb_kinase PF01256.12 EPS28901.1 - 2.4e-05 23.7 1.6 5.1e-05 22.6 0.2 1.9 2 0 0 2 2 2 1 Carbohydrate kinase HK PF02110.10 EPS28901.1 - 0.00029 20.0 0.6 0.0073 15.5 0.1 2.2 2 0 0 2 2 2 1 Hydroxyethylthiazole kinase family DEAD PF00270.24 EPS28902.1 - 4e-45 153.3 0.0 1.6e-43 148.1 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPS28902.1 - 9.9e-28 95.8 0.0 2.2e-27 94.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EPS28902.1 - 0.0032 17.4 0.0 0.0052 16.7 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.10 EPS28902.1 - 0.005 16.6 0.0 0.018 14.8 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EPS28902.1 - 0.012 14.0 0.0 0.58 8.4 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1253) DUF2443 PF10398.4 EPS28902.1 - 0.049 13.4 0.5 0.12 12.1 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) Desmo_N PF06771.6 EPS28902.1 - 0.2 11.6 0.9 27 4.7 0.0 3.2 2 1 1 3 3 3 0 Viral Desmoplakin N-terminus Lipase_GDSL PF00657.17 EPS28903.1 - 6e-09 36.0 0.1 1.7e-08 34.6 0.1 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EPS28903.1 - 2.8e-05 24.3 0.0 5.2e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family PPR_2 PF13041.1 EPS28908.1 - 6e-20 70.9 0.0 1.7e-14 53.5 0.0 3.2 3 1 0 3 3 3 2 PPR repeat family PPR PF01535.15 EPS28908.1 - 1.3e-05 24.7 0.0 0.0027 17.5 0.0 3.8 4 0 0 4 4 4 1 PPR repeat PPR_3 PF13812.1 EPS28908.1 - 0.0011 19.0 3.5 0.046 14.0 0.0 4.6 6 0 0 6 6 6 1 Pentatricopeptide repeat domain Yip1 PF04893.12 EPS28909.1 - 7.5e-12 45.0 17.3 1.2e-11 44.3 11.9 1.4 1 1 0 1 1 1 1 Yip1 domain DUF1282 PF06930.7 EPS28909.1 - 0.2 11.2 8.9 0.37 10.4 6.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) Ran_BP1 PF00638.13 EPS28910.1 - 6.5e-18 64.9 0.5 1.2e-17 64.1 0.0 1.6 2 0 0 2 2 2 1 RanBP1 domain Methyltransf_23 PF13489.1 EPS28911.1 - 7.5e-11 42.0 0.0 1.2e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPS28911.1 - 2.1e-10 40.9 0.0 5.8e-10 39.5 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPS28911.1 - 2.5e-10 40.1 0.0 3.2e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS28911.1 - 1.5e-09 38.3 0.0 2.4e-09 37.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPS28911.1 - 6.4e-09 36.0 0.0 1.6e-08 34.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPS28911.1 - 1.1e-08 35.4 0.0 2.4e-08 34.3 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPS28911.1 - 9.9e-06 25.5 0.0 1.7e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPS28911.1 - 0.00011 21.5 0.0 0.00017 21.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.13 EPS28911.1 - 0.00048 19.4 0.0 0.00078 18.6 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_4 PF02390.12 EPS28911.1 - 0.0036 16.3 0.0 0.0081 15.2 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase PCMT PF01135.14 EPS28911.1 - 0.017 14.6 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.14 EPS28911.1 - 0.017 15.1 0.0 0.027 14.4 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_32 PF13679.1 EPS28911.1 - 0.022 14.4 0.0 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 EPS28911.1 - 0.023 13.7 0.0 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase FmrO PF07091.6 EPS28911.1 - 0.024 13.6 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) CheR PF01739.13 EPS28911.1 - 0.081 12.2 0.0 0.64 9.2 0.0 2.0 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain DEAD PF00270.24 EPS28912.1 - 4.7e-24 84.7 0.0 8.9e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPS28912.1 - 7.4e-11 41.7 0.0 1.9e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1998 PF09369.5 EPS28912.1 - 5.1e-10 39.7 0.2 2.1e-09 37.7 0.1 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1998) ResIII PF04851.10 EPS28912.1 - 0.013 15.3 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit EB1 PF03271.12 EPS28913.1 - 0.13 12.3 0.2 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 EB1-like C-terminal motif Fungal_trans_2 PF11951.3 EPS28914.1 - 8.2e-12 44.4 0.6 8.2e-12 44.4 0.4 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS28914.1 - 3.8e-07 29.8 9.5 6.3e-07 29.2 6.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_16 PF10294.4 EPS28915.1 - 4e-08 32.9 0.0 6e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase DUF993 PF06187.6 EPS28915.1 - 0.11 10.9 0.1 0.17 10.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF993) Formyl_trans_N PF00551.14 EPS28916.1 - 9.6e-38 129.5 0.1 1.1e-37 129.3 0.1 1.0 1 0 0 1 1 1 1 Formyl transferase zf-RING_2 PF13639.1 EPS28917.1 - 2.4e-15 56.0 4.9 3.9e-15 55.4 3.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EPS28917.1 - 1.3e-09 38.0 2.1 2.3e-09 37.2 1.4 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EPS28917.1 - 1.3e-07 31.1 4.8 1.9e-07 30.5 3.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPS28917.1 - 1.3e-07 31.5 4.7 2.2e-07 30.8 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPS28917.1 - 6.6e-06 25.7 3.4 1e-05 25.1 2.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EPS28917.1 - 1.2e-05 25.0 0.6 2.6e-05 23.9 0.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 EPS28917.1 - 2.5e-05 23.8 2.4 4.1e-05 23.1 1.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 EPS28917.1 - 0.0009 19.2 5.9 0.0014 18.5 4.1 1.3 1 0 0 1 1 1 1 RING-variant domain zf-Nse PF11789.3 EPS28917.1 - 0.018 14.5 2.0 0.036 13.5 1.4 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 EPS28917.1 - 0.043 13.4 4.1 0.07 12.7 2.8 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 EPS28917.1 - 0.051 13.5 3.5 0.093 12.7 2.4 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.6 EPS28917.1 - 0.068 13.1 2.3 0.12 12.3 1.6 1.3 1 0 0 1 1 1 0 RING-like domain zf-RING_UBOX PF13445.1 EPS28917.1 - 0.2 11.4 2.6 0.44 10.3 1.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger ARL6IP6 PF15062.1 EPS28917.1 - 0.77 9.7 3.4 0.41 10.5 0.1 2.2 2 0 0 2 2 2 0 Haemopoietic lineage transmembrane helix RNA_pol_I_TF PF04090.7 EPS28918.1 - 3.7e-12 45.9 0.0 1e-10 41.2 0.0 2.3 1 1 0 1 1 1 1 RNA polymerase I specific initiation factor ECM11 PF15463.1 EPS28919.1 - 5.8e-39 133.5 0.0 5.8e-39 133.5 0.0 2.6 3 0 0 3 3 3 1 Extracellular mutant protein 11 VPS9 PF02204.13 EPS28920.1 - 1e-26 92.9 0.1 4.2e-26 90.9 0.0 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain RED_N PF07808.8 EPS28922.1 - 1.6e-07 30.7 0.5 3.7e-07 29.5 0.3 1.7 1 0 0 1 1 1 1 RED-like protein N-terminal region GvpG PF05120.7 EPS28922.1 - 0.27 11.0 3.4 0.15 11.8 0.6 1.9 2 0 0 2 2 2 0 Gas vesicle protein G zf-UBR PF02207.15 EPS28923.1 - 3.9e-17 61.7 14.9 9.4e-17 60.5 10.3 1.7 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) zf-RING_2 PF13639.1 EPS28923.1 - 0.00019 21.2 1.3 0.00019 21.2 0.9 4.6 4 1 0 4 4 4 1 Ring finger domain ClpS PF02617.12 EPS28923.1 - 0.0012 18.5 0.0 0.0029 17.3 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS SDA1 PF05285.7 EPS28923.1 - 0.0017 17.6 2.1 0.0033 16.7 1.5 1.4 1 0 0 1 1 1 1 SDA1 BUD22 PF09073.5 EPS28923.1 - 1.7 7.5 7.7 4.2 6.3 5.4 1.6 1 0 0 1 1 1 0 BUD22 YL1 PF05764.8 EPS28923.1 - 4.2 6.9 16.4 0.28 10.7 7.5 1.8 2 0 0 2 2 2 0 YL1 nuclear protein Nop14 PF04147.7 EPS28923.1 - 4.2 5.1 18.7 0.11 10.4 8.3 1.6 2 0 0 2 2 2 0 Nop14-like family UCR_UQCRX_QCR9 PF05365.7 EPS28924.1 - 2e-27 94.5 1.1 2.2e-27 94.4 0.8 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Mago-bind PF09282.5 EPS28925.1 - 4.4e-13 48.5 5.5 8e-13 47.6 3.8 1.5 1 0 0 1 1 1 1 Mago binding RNF111_N PF15303.1 EPS28925.1 - 1 8.7 11.3 1.9 7.9 7.8 1.4 1 1 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus eIF-3c_N PF05470.7 EPS28925.1 - 1.2 7.0 8.4 1.6 6.7 5.8 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Borrelia_P83 PF05262.6 EPS28925.1 - 9.6 4.3 12.3 12 4.0 8.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein TATR PF03430.8 EPS28925.1 - 9.6 4.6 6.7 12 4.3 4.6 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Amino_oxidase PF01593.19 EPS28926.1 - 1.1e-18 67.6 0.0 3.3e-18 66.0 0.0 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EPS28926.1 - 8.1e-13 48.1 0.0 2.6e-12 46.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EPS28926.1 - 1.7e-06 27.1 0.0 2.4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EPS28926.1 - 0.0041 16.9 0.0 0.014 15.2 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.9 EPS28926.1 - 0.037 12.4 0.0 0.12 10.8 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.22 EPS28926.1 - 0.074 13.4 0.0 0.23 11.8 0.0 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPS28926.1 - 0.077 13.0 0.0 0.25 11.3 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EPS28926.1 - 0.18 10.5 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain zf-CCCH_2 PF14608.1 EPS28927.1 - 9.1e-10 38.1 57.3 2e-05 24.4 9.1 5.4 5 0 0 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type Nab2 PF11517.3 EPS28927.1 - 0.0063 16.5 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) PAM2 PF07145.10 EPS28927.1 - 0.043 13.3 0.4 0.19 11.2 0.3 2.2 1 0 0 1 1 1 0 Ataxin-2 C-terminal region TRAM_LAG1_CLN8 PF03798.11 EPS28928.1 - 7.3e-41 139.8 19.1 7.3e-41 139.8 13.2 1.5 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EPS28928.1 - 3.2e-19 68.2 0.9 7.6e-19 66.9 0.0 2.1 2 0 0 2 2 2 1 TRAM1-like protein TMEM156 PF15106.1 EPS28928.1 - 1.2 8.3 6.2 0.3 10.2 0.2 2.1 2 0 0 2 2 2 0 TMEM156 protein family PMP22_Claudin PF00822.15 EPS28929.1 - 2 8.0 11.4 0.074 12.7 0.8 3.0 4 0 0 4 4 4 0 PMP-22/EMP/MP20/Claudin family 4F5 PF04419.9 EPS28930.1 - 4.1e-11 43.4 9.4 4.1e-11 43.4 6.5 2.4 2 1 0 2 2 2 1 4F5 protein family PPTA PF01239.17 EPS28931.1 - 0.0032 16.7 5.5 0.28 10.6 0.1 3.1 3 0 0 3 3 3 2 Protein prenyltransferase alpha subunit repeat CHD5 PF04420.9 EPS28932.1 - 6e-61 204.8 2.6 8.3e-61 204.3 1.8 1.2 1 0 0 1 1 1 1 CHD5-like protein RRM_1 PF00076.17 EPS28934.1 - 5.4e-14 51.5 0.0 1.1e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS28934.1 - 5.8e-10 39.0 0.0 1.1e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS28934.1 - 9.6e-07 28.5 0.1 2.1e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Plasmid_Txe PF06769.8 EPS28934.1 - 0.032 14.0 1.0 0.032 14.0 0.7 2.0 2 0 0 2 2 2 0 Plasmid encoded toxin Txe Nup35_RRM_2 PF14605.1 EPS28934.1 - 0.042 13.6 0.0 0.084 12.6 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif SMN PF06003.7 EPS28935.1 - 2.3e-08 33.4 10.2 6.3e-06 25.4 1.9 2.1 1 1 1 2 2 2 2 Survival motor neuron protein (SMN) Med15 PF09606.5 EPS28935.1 - 0.019 13.1 0.4 0.021 13.0 0.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3729 PF12526.3 EPS28935.1 - 0.024 15.9 4.5 0.034 15.5 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3729) Dicistro_VP4 PF11492.3 EPS28936.1 - 0.026 14.5 0.4 0.53 10.3 0.0 2.4 2 0 0 2 2 2 0 Cricket paralysis virus, VP4 AIF_C PF14721.1 EPS28936.1 - 0.11 12.7 0.9 0.14 12.3 0.6 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term AAA_33 PF13671.1 EPS28938.1 - 8.3e-19 67.8 0.0 9.8e-19 67.6 0.0 1.0 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EPS28938.1 - 1e-09 37.8 0.0 1.3e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 EPS28938.1 - 1.2e-09 38.5 0.0 1.5e-09 38.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPS28938.1 - 2.1e-08 34.9 0.0 2.9e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 AAA domain CPT PF07931.7 EPS28938.1 - 9.7e-05 22.0 0.0 0.00016 21.3 0.0 1.3 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein KTI12 PF08433.5 EPS28938.1 - 0.00013 21.2 0.0 0.00018 20.8 0.0 1.1 1 0 0 1 1 1 1 Chromatin associated protein KTI12 APS_kinase PF01583.15 EPS28938.1 - 0.0015 18.2 0.0 0.009 15.6 0.0 1.9 1 1 0 1 1 1 1 Adenylylsulphate kinase SKI PF01202.17 EPS28938.1 - 0.0054 16.6 0.0 0.01 15.7 0.0 1.4 1 1 0 1 1 1 1 Shikimate kinase TOBE PF03459.12 EPS28938.1 - 0.08 13.0 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 TOBE domain DUF3431 PF11913.3 EPS28939.1 - 1.1e-71 240.8 0.0 1.7e-71 240.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DUF3687 PF12459.3 EPS28939.1 - 0.02 14.1 0.1 0.038 13.2 0.1 1.4 1 0 0 1 1 1 0 D-Ala-teichoic acid biosynthesis protein Thiolase_C PF02803.13 EPS28940.1 - 4.9e-12 45.3 0.6 1.6e-10 40.5 0.0 2.5 1 1 1 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EPS28940.1 - 7.8e-08 31.8 0.1 9.2e-06 25.2 0.0 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 EPS28940.1 - 2.3e-06 26.8 1.1 1.1e-05 24.5 0.0 2.5 2 1 1 3 3 3 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 EPS28940.1 - 0.0057 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain SpoVAD PF07451.6 EPS28940.1 - 0.013 13.9 0.1 0.028 12.8 0.1 1.5 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) Mito_carr PF00153.22 EPS28941.1 - 7.5e-47 156.9 3.0 2.6e-17 62.2 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3337 PF11816.3 EPS28942.1 - 4.5e-54 184.0 3.5 2.2e-43 148.9 0.1 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF3337) FTA4 PF13093.1 EPS28943.1 - 0.052 12.9 2.6 1.3 8.4 0.0 2.1 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF869 PF05911.6 EPS28943.1 - 0.17 10.0 0.0 0.2 9.8 0.0 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Ank_2 PF12796.2 EPS28944.1 - 1.4e-24 86.2 0.1 8.5e-13 48.4 0.1 2.5 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EPS28944.1 - 5.9e-21 73.1 3.9 1.2e-06 28.0 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 EPS28944.1 - 2.8e-19 69.0 3.0 1.6e-07 31.6 0.1 4.8 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPS28944.1 - 2.3e-18 65.7 1.0 1.3e-08 34.8 0.0 4.3 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPS28944.1 - 1.2e-17 62.2 1.0 0.00015 21.7 0.0 6.2 6 0 0 6 6 6 4 Ankyrin repeat Transposase_23 PF03017.9 EPS28945.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 TNP1/EN/SPM transposase BRO1 PF03097.13 EPS28946.1 - 5.4e-117 390.7 0.0 1.4e-116 389.3 0.0 1.7 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EPS28946.1 - 8.7e-82 274.3 15.4 9.9e-82 274.2 9.5 2.0 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV TRP PF06011.7 EPS28949.1 - 7e-103 344.5 27.9 8.9e-103 344.1 19.4 1.0 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EPS28949.1 - 2.8e-29 101.9 0.1 4.3e-29 101.3 0.1 1.3 1 0 0 1 1 1 1 ML-like domain DUF912 PF06024.7 EPS28949.1 - 0.45 10.5 5.2 3 7.9 1.2 2.9 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Baculo_11_kDa PF06143.6 EPS28949.1 - 0.5 9.7 7.2 2.4 7.6 0.6 2.9 3 0 0 3 3 3 0 Baculovirus 11 kDa family F-box PF00646.28 EPS28950.1 - 0.033 13.8 1.7 0.035 13.7 0.1 1.9 2 0 0 2 2 2 0 F-box domain Metallophos PF00149.23 EPS28951.1 - 3.8e-38 130.8 0.8 5.1e-38 130.4 0.5 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Zn_clus PF00172.13 EPS28952.1 - 7.1e-09 35.4 6.5 1.3e-08 34.5 4.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SR-25 PF10500.4 EPS28952.1 - 0.16 11.4 5.5 0.34 10.3 3.8 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Aldedh PF00171.17 EPS28953.1 - 3.3e-185 615.8 0.1 3.8e-185 615.6 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Phage_term_smal PF05944.7 EPS28953.1 - 0.036 13.7 0.2 0.83 9.3 0.0 2.3 2 0 0 2 2 2 0 Phage small terminase subunit DUF1487 PF07368.6 EPS28953.1 - 0.12 11.5 0.0 1.2 8.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Cu_amine_oxid PF01179.15 EPS28955.1 - 3.3e-168 559.7 0.0 4e-168 559.4 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EPS28955.1 - 7.8e-20 70.8 0.0 1.8e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EPS28955.1 - 1.4e-13 50.7 0.2 2.8e-13 49.7 0.1 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Zn_clus PF00172.13 EPS28957.1 - 1.1e-09 37.9 10.6 1.9e-09 37.2 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LysM PF01476.15 EPS28959.1 - 3.7e-05 23.5 0.0 6.9e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 LysM domain Rer1 PF03248.8 EPS28960.1 - 1.8e-83 278.4 2.3 2.1e-83 278.2 1.6 1.0 1 0 0 1 1 1 1 Rer1 family DUF4400 PF14348.1 EPS28960.1 - 0.53 9.6 8.9 1.7 8.0 2.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4400) ECH PF00378.15 EPS28961.1 - 5.1e-71 238.6 0.1 6.3e-71 238.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EPS28961.1 - 0.0078 16.0 0.8 0.2 11.3 0.1 2.2 2 0 0 2 2 2 1 Peptidase family S49 ECH_C PF13766.1 EPS28961.1 - 0.011 15.8 0.0 0.022 14.9 0.0 1.4 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region PAS_3 PF08447.6 EPS28962.1 - 1.3e-09 38.0 0.0 1.3e-07 31.5 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS PF00989.19 EPS28962.1 - 1.1e-07 31.5 0.0 0.00049 19.8 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.1 EPS28962.1 - 2.3e-07 31.1 0.0 0.00025 21.3 0.0 2.3 2 0 0 2 2 2 2 PAS domain PAS_11 PF14598.1 EPS28962.1 - 8.1e-05 22.5 0.0 0.0013 18.6 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 EPS28962.1 - 0.0031 17.5 0.0 0.17 11.8 0.0 2.4 2 0 0 2 2 2 1 PAS fold Sugar_tr PF00083.19 EPS28963.1 - 3.8e-84 282.8 18.5 4.5e-84 282.6 12.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS28963.1 - 3.7e-16 58.7 25.1 9.6e-13 47.5 13.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ATP_transf PF09830.4 EPS28964.1 - 6.9e-18 64.2 0.0 1.1e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 ATP adenylyltransferase AKAP7_NLS PF10469.4 EPS28966.1 - 5.3e-15 55.6 0.0 1.7e-14 54.0 0.0 1.8 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Sec6 PF06046.8 EPS28967.1 - 9.8e-170 565.3 9.4 9.8e-170 565.3 6.5 1.5 2 0 0 2 2 2 1 Exocyst complex component Sec6 DUF572 PF04502.8 EPS28967.1 - 2.3 7.3 7.9 5.3 6.1 5.5 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ribosomal_L30 PF00327.15 EPS28968.1 - 9.7e-14 50.6 0.1 1.3e-13 50.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Pyridoxal_deC PF00282.14 EPS28969.1 - 5.6e-21 74.4 0.0 7.9e-21 73.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EPS28969.1 - 4e-08 32.3 0.0 2.8e-07 29.6 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EPS28969.1 - 2.5e-06 26.6 0.0 4.5e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EPS28969.1 - 0.002 17.2 0.0 0.0034 16.4 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EPS28969.1 - 0.12 10.6 0.0 0.2 9.9 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF1744 PF08490.7 EPS28969.1 - 0.14 10.6 0.0 0.22 10.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) HMGL-like PF00682.14 EPS28970.1 - 9.7e-71 238.1 0.5 1.4e-70 237.6 0.4 1.2 1 0 0 1 1 1 1 HMGL-like PTH2 PF01981.11 EPS28972.1 - 2.2e-41 140.1 0.1 2.9e-41 139.7 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 S-antigen PF05756.6 EPS28972.1 - 0.4 10.6 2.9 0.62 10.0 2.0 1.3 1 0 0 1 1 1 0 S-antigen protein SART-1 PF03343.8 EPS28973.1 - 9.5e-181 602.2 61.9 1.1e-180 602.0 42.9 1.0 1 0 0 1 1 1 1 SART-1 family Phage_lysozyme PF00959.14 EPS28973.1 - 0.73 10.1 6.0 0.2 11.9 1.3 2.1 2 1 0 2 2 2 0 Phage lysozyme Aminotran_1_2 PF00155.16 EPS28974.1 - 9.5e-94 314.3 0.0 1.1e-93 314.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II ABC_tran PF00005.22 EPS28975.1 - 6.5e-50 168.9 0.0 7.5e-32 110.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EPS28975.1 - 5.2e-30 104.8 33.2 1.6e-20 73.6 6.7 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 EPS28975.1 - 1.7e-14 54.4 0.0 6.8e-05 22.9 0.0 4.2 3 1 0 3 3 3 2 AAA domain AAA_33 PF13671.1 EPS28975.1 - 1.9e-06 27.7 0.0 0.015 15.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 EPS28975.1 - 2.6e-06 26.8 2.1 0.00034 19.9 0.4 3.4 2 2 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EPS28975.1 - 1.9e-05 24.7 0.1 0.45 10.6 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EPS28975.1 - 2e-05 24.1 0.6 0.11 11.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EPS28975.1 - 2.1e-05 23.9 1.6 0.16 11.5 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EPS28975.1 - 3.8e-05 24.4 0.1 0.07 13.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EPS28975.1 - 0.00026 21.3 0.0 0.47 10.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EPS28975.1 - 0.0018 18.2 0.1 0.44 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 EPS28975.1 - 0.002 17.6 0.1 3 7.1 0.0 2.9 3 0 0 3 3 3 2 AAA-like domain Miro PF08477.8 EPS28975.1 - 0.0034 17.8 0.0 1.1 9.8 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 EPS28975.1 - 0.0038 17.1 0.3 2.9 7.8 0.1 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EPS28975.1 - 0.0038 16.4 0.1 0.48 9.5 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA PF00004.24 EPS28975.1 - 0.0041 17.3 0.0 0.24 11.6 0.0 3.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EPS28975.1 - 0.0076 15.9 0.5 0.59 9.7 0.0 2.9 3 0 0 3 3 2 1 NACHT domain Mg_chelatase PF01078.16 EPS28975.1 - 0.014 14.5 0.0 4.7 6.2 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EPS28975.1 - 0.02 14.8 0.0 1 9.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 EPS28975.1 - 0.024 14.8 0.0 5.2 7.3 0.0 2.5 2 0 0 2 2 2 0 RNA helicase UPF0079 PF02367.12 EPS28975.1 - 0.025 14.2 1.8 0.042 13.4 0.2 2.0 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_5 PF07728.9 EPS28975.1 - 0.056 13.1 2.1 2.6 7.7 0.2 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 EPS28975.1 - 0.059 13.2 0.3 10 6.1 0.0 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit PduV-EutP PF10662.4 EPS28975.1 - 0.073 12.5 0.7 0.77 9.2 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 EPS28975.1 - 0.092 12.5 0.4 2.7 7.7 0.0 2.4 2 0 0 2 2 2 0 Dynamin family DUF87 PF01935.12 EPS28975.1 - 0.099 12.4 0.1 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 MobB PF03205.9 EPS28975.1 - 0.11 12.2 1.1 16 5.1 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Rad17 PF03215.10 EPS28975.1 - 0.18 10.4 0.1 0.36 9.4 0.1 1.4 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_23 PF13476.1 EPS28975.1 - 0.32 11.3 3.8 8.2 6.6 0.2 2.4 2 0 0 2 2 2 0 AAA domain CoxIIa PF08113.6 EPS28975.1 - 1.5 8.5 7.3 1.3 8.8 2.8 2.5 1 1 1 2 2 2 0 Cytochrome c oxidase subunit IIa family CtaG_Cox11 PF04442.9 EPS28976.1 - 0.014 15.2 4.4 16 5.2 0.1 3.7 1 1 6 7 7 7 0 Cytochrome c oxidase assembly protein CtaG/Cox11 RuBisCO_large PF00016.15 EPS28976.1 - 0.12 11.1 2.1 17 4.1 0.0 3.2 1 1 1 3 3 3 0 Ribulose bisphosphate carboxylase large chain, catalytic domain HS1_rep PF02218.10 EPS28976.1 - 0.38 10.6 30.5 31 4.5 0.7 7.8 1 1 7 8 8 8 0 Repeat in HS1/Cortactin Gla PF00594.15 EPS28976.1 - 2.2 8.0 23.0 87 2.9 0.0 8.4 9 0 0 9 9 9 0 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain DUF3328 PF11807.3 EPS28977.1 - 1.3e-42 145.9 3.4 1.7e-42 145.5 2.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EPS28978.1 - 1e-43 149.5 0.1 1.4e-43 149.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) MFS_1 PF07690.11 EPS28979.1 - 4.2e-22 78.3 41.7 7.6e-18 64.3 13.5 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Carn_acyltransf PF00755.15 EPS28980.1 - 7.3e-80 268.7 0.0 1e-79 268.2 0.0 1.2 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase ketoacyl-synt PF00109.21 EPS28980.1 - 2e-79 266.6 0.1 3.9e-79 265.7 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EPS28980.1 - 7.8e-60 202.8 0.8 1.5e-59 201.9 0.6 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EPS28980.1 - 1.4e-52 177.9 0.0 9.2e-52 175.3 0.0 2.5 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 EPS28980.1 - 2.1e-44 151.8 0.0 3.5e-44 151.1 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EPS28980.1 - 3.2e-41 141.0 2.7 3.4e-41 140.9 0.0 2.5 3 0 0 3 3 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EPS28980.1 - 1.3e-36 125.0 0.1 4.3e-36 123.3 0.1 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EPS28980.1 - 4.2e-20 71.6 0.5 3.4e-19 68.6 0.0 2.8 4 0 0 4 4 3 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPS28980.1 - 4.7e-13 50.1 0.0 2.3e-12 47.9 0.0 2.3 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EPS28980.1 - 1.3e-10 41.6 0.0 4.3e-10 39.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPS28980.1 - 9.2e-09 35.2 0.0 2.7e-08 33.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPS28980.1 - 1.1e-07 31.5 0.0 3e-07 30.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPS28980.1 - 4.2e-07 30.3 0.0 1.3e-06 28.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPS28980.1 - 1.1e-06 27.9 0.0 2.3e-05 23.6 0.0 2.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family PP-binding PF00550.20 EPS28980.1 - 1.3e-06 28.5 0.4 3.8e-06 27.0 0.3 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_18 PF12847.2 EPS28980.1 - 1.2e-05 25.7 0.0 5.1e-05 23.8 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 EPS28980.1 - 1.4e-05 24.6 0.0 3.5e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EPS28980.1 - 0.00021 21.3 0.4 0.024 14.6 0.0 3.2 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 EPS28980.1 - 0.00032 19.4 0.0 0.00078 18.2 0.0 1.6 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family ADH_N PF08240.7 EPS28980.1 - 0.00073 19.2 0.2 0.0019 17.9 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.18 EPS28980.1 - 0.0019 17.2 0.2 0.0038 16.2 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_25 PF13649.1 EPS28980.1 - 0.015 15.6 0.0 0.046 14.0 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 EPS28980.1 - 0.056 12.9 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase RTA1 PF04479.8 EPS28981.1 - 9.5e-45 152.8 9.5 9.5e-45 152.8 6.6 1.5 2 0 0 2 2 2 1 RTA1 like protein DUF3007 PF11460.3 EPS28981.1 - 0.11 12.5 0.7 2.4 8.2 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) NnrU PF07298.6 EPS28981.1 - 1.5 8.1 10.2 0.032 13.5 1.1 2.4 2 1 1 3 3 3 0 NnrU protein ABC2_membrane_5 PF13346.1 EPS28981.1 - 1.8 7.8 16.4 0.33 10.1 8.1 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein Sulfotransfer_3 PF13469.1 EPS28982.1 - 0.027 15.4 4.1 0.13 13.1 2.9 2.2 1 1 0 1 1 1 0 Sulfotransferase family MFS_1 PF07690.11 EPS28983.1 - 1.2e-36 126.1 45.7 2e-36 125.4 31.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Transferase PF02458.10 EPS28984.1 - 6.7e-12 44.5 0.0 1.6e-11 43.3 0.0 1.5 1 1 0 1 1 1 1 Transferase family DUF155 PF02582.9 EPS28985.1 - 2.6e-58 196.7 0.0 3.8e-58 196.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 DUF2561 PF10812.3 EPS28985.1 - 0.028 14.0 0.1 0.07 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) zf-H2C2_2 PF13465.1 EPS28990.1 - 1.3e-19 69.3 25.4 2.9e-07 30.4 0.9 5.4 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 EPS28990.1 - 1.4e-19 69.1 26.1 2.6e-05 24.2 1.2 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPS28990.1 - 6.5e-12 44.9 27.1 0.00047 20.2 3.1 4.5 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EPS28990.1 - 4.6e-05 23.4 8.2 0.28 11.3 0.1 4.4 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EPS28990.1 - 0.0015 18.6 15.2 0.023 14.9 0.1 4.1 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EPS28990.1 - 0.05 13.5 16.9 1.7 8.6 0.9 4.3 4 0 0 4 4 4 0 C2H2-type zinc finger XPA_N PF01286.13 EPS28990.1 - 0.088 12.5 0.3 0.088 12.5 0.2 3.2 5 0 0 5 5 5 0 XPA protein N-terminal Yippee-Mis18 PF03226.9 EPS28990.1 - 0.14 12.2 1.6 7.1 6.7 0.2 2.3 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly C1_4 PF07975.7 EPS28990.1 - 0.21 11.6 4.4 1.1 9.2 0.1 2.8 1 1 1 2 2 2 0 TFIIH C1-like domain DDE_Tnp_1_6 PF13751.1 EPS28990.1 - 0.28 11.2 6.9 0.04 13.9 1.5 1.9 2 0 0 2 2 2 0 Transposase DDE domain Zn-ribbon_8 PF09723.5 EPS28990.1 - 0.54 10.2 9.5 25 4.9 1.0 3.8 3 1 0 3 3 3 0 Zinc ribbon domain C1_1 PF00130.17 EPS28990.1 - 1.1 9.0 6.7 0.93 9.2 0.8 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HNH PF01844.18 EPS28990.1 - 7.4 6.5 7.2 21 5.0 0.1 3.6 4 0 0 4 4 4 0 HNH endonuclease Fer4_18 PF13746.1 EPS28990.1 - 8.9 6.8 7.7 5.9 7.3 0.2 2.7 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fringe PF02434.11 EPS28991.1 - 3.5e-12 46.0 0.1 8.7e-12 44.7 0.0 1.6 1 1 0 1 1 1 1 Fringe-like DUF604 PF04646.7 EPS28991.1 - 2.3e-08 33.5 0.0 5e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF604 E1-E2_ATPase PF00122.15 EPS28992.1 - 1.4e-20 73.3 0.0 1.4e-20 73.3 0.0 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EPS28992.1 - 1.5e-17 64.7 0.0 8.9e-17 62.2 0.0 2.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EPS28992.1 - 1.2e-14 54.9 0.3 2e-13 50.9 0.2 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPS28992.1 - 4.7e-12 45.6 0.0 2.3e-11 43.5 0.0 2.3 2 1 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EPS28992.1 - 0.001 18.6 0.2 0.0031 17.1 0.2 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF4181 PF13789.1 EPS28992.1 - 0.017 15.0 0.1 0.017 15.0 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4181) HCV_NS5a_1b PF08301.8 EPS28992.1 - 0.11 12.8 0.5 0.32 11.3 0.1 1.9 2 0 0 2 2 2 0 Hepatitis C virus non-structural 5a domain 1b DPBB_1 PF03330.13 EPS28992.1 - 0.21 11.5 0.9 0.78 9.7 0.0 2.4 3 0 0 3 3 3 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel vWA-TerF-like PF10138.4 EPS28993.1 - 9.1e-05 22.3 0.0 0.00015 21.6 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus Pro-rich PF15240.1 EPS28993.1 - 0.0047 17.0 37.3 0.0047 17.0 25.8 2.5 2 0 0 2 2 2 1 Proline-rich GFO_IDH_MocA PF01408.17 EPS28994.1 - 0.00014 22.4 0.2 0.00034 21.1 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold SRP72 PF08492.7 EPS28995.1 - 1.3e-16 60.6 2.3 1.3e-16 60.6 1.6 2.4 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_19 PF14559.1 EPS28995.1 - 8.4e-06 26.0 31.9 0.026 14.8 1.1 7.5 5 3 4 9 9 9 4 Tetratricopeptide repeat Apc3 PF12895.2 EPS28995.1 - 0.0001 22.3 15.7 0.29 11.2 2.3 4.9 3 1 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EPS28995.1 - 0.00011 21.6 5.7 0.38 10.6 0.0 5.3 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EPS28995.1 - 0.0052 16.6 20.1 0.13 12.2 0.5 5.5 4 2 2 6 6 6 2 Tetratricopeptide repeat PPR PF01535.15 EPS28995.1 - 0.028 14.3 0.0 45 4.3 0.0 4.0 4 0 0 4 4 4 0 PPR repeat DUF711 PF05167.7 EPS28995.1 - 0.068 11.8 1.0 0.29 9.8 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised ACR (DUF711) TPR_4 PF07721.9 EPS28995.1 - 0.072 13.5 16.6 2.1 9.0 0.0 5.3 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EPS28995.1 - 0.1 13.2 32.9 1.1 10.0 0.0 9.5 6 3 4 11 11 10 0 Tetratricopeptide repeat TPR_2 PF07719.12 EPS28995.1 - 0.17 11.8 21.5 3.4 7.8 0.0 7.2 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_17 PF13431.1 EPS28995.1 - 0.3 11.3 4.9 7.1 7.0 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EPS28995.1 - 0.51 10.0 10.7 19 5.0 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 EPS28995.1 - 9.1 6.3 9.5 7.7 6.6 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Aminotran_3 PF00202.16 EPS28997.1 - 6.8e-87 291.4 0.1 8.1e-87 291.2 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EPS28997.1 - 0.00058 18.9 0.0 0.0013 17.7 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class I and II Homeobox PF00046.24 EPS28999.1 - 1.2e-19 69.6 2.6 2.4e-19 68.6 1.8 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EPS28999.1 - 0.00019 21.0 2.3 0.0018 17.9 0.6 2.5 2 0 0 2 2 2 1 Homeobox KN domain PGP_phosphatase PF09419.5 EPS29000.1 - 3e-60 202.4 0.0 3.5e-60 202.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 EPS29000.1 - 0.00028 20.5 0.0 0.00046 19.8 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like LSM PF01423.17 EPS29001.1 - 4.3e-14 51.8 0.5 5.8e-14 51.4 0.3 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EPS29001.1 - 0.066 13.1 0.2 0.12 12.2 0.2 1.5 1 1 0 1 1 1 0 Ataxin 2 SM domain Adaptin_binding PF10199.4 EPS29002.1 - 9.4e-19 68.0 2.5 9.4e-19 68.0 1.7 2.0 2 0 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 Tom22 PF04281.8 EPS29002.1 - 9.5 5.7 12.5 1.7 8.1 0.2 3.2 3 0 0 3 3 3 0 Mitochondrial import receptor subunit Tom22 PTPLA PF04387.9 EPS29003.1 - 4.4e-55 185.5 4.0 6.3e-55 185.0 2.8 1.2 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA CbtB PF09489.5 EPS29003.1 - 0.27 11.1 1.0 1.1 9.1 0.0 2.5 3 0 0 3 3 3 0 Probable cobalt transporter subunit (CbtB) Hpt PF01627.18 EPS29006.1 - 2.3e-11 43.5 0.0 4.1e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Hpt domain PilP PF04351.8 EPS29006.1 - 0.38 10.6 5.7 7 6.5 0.0 2.2 2 0 0 2 2 2 0 Pilus assembly protein, PilP Phageshock_PspD PF09584.5 EPS29007.1 - 0.13 11.9 0.1 0.91 9.2 0.0 2.0 2 0 0 2 2 2 0 Phage shock protein PspD (Phageshock_PspD) DUF607 PF04678.8 EPS29008.1 - 4.5e-45 153.7 0.2 1.3e-44 152.2 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF607 dsrm PF00035.20 EPS29009.1 - 5.9e-05 23.5 0.0 0.00011 22.7 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.1 EPS29009.1 - 0.019 15.2 0.2 0.035 14.3 0.2 1.4 1 1 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 p450 PF00067.17 EPS29010.1 - 5.3e-65 219.7 0.0 6.9e-65 219.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 EPS29011.1 - 9.4e-08 31.9 0.0 2.2e-07 30.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPS29011.1 - 0.00037 20.9 0.0 0.001 19.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPS29011.1 - 0.012 16.0 0.0 0.039 14.4 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.2 EPS29011.1 - 0.02 15.4 0.0 0.11 13.0 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EPS29011.1 - 0.074 13.4 0.0 0.32 11.3 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Prenyltrans PF00432.16 EPS29012.1 - 8.5e-39 130.8 33.1 2.4e-12 46.2 0.8 6.3 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EPS29012.1 - 5.1e-27 94.5 0.0 3.6e-17 62.7 0.1 4.2 1 1 4 5 5 5 5 Prenyltransferase-like Prenyltrans_1 PF13243.1 EPS29012.1 - 1.2e-05 25.2 0.0 0.00026 20.9 0.0 2.7 1 1 1 2 2 2 1 Prenyltransferase-like Zn_clus PF00172.13 EPS29014.1 - 0.0033 17.3 7.7 0.006 16.4 5.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ubiquitin PF00240.18 EPS29015.1 - 1.1e-124 405.8 24.5 1e-33 114.5 0.6 4.5 4 1 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.3 EPS29015.1 - 3e-72 238.2 19.4 4e-19 68.0 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EPS29015.1 - 1.9e-22 79.3 10.4 0.00014 22.0 0.1 5.4 4 3 0 4 4 4 4 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EPS29015.1 - 1.3e-19 70.4 2.7 0.00067 19.3 0.0 4.4 4 1 0 4 4 4 4 Telomere stability and silencing DUF2407 PF10302.4 EPS29015.1 - 1.7e-13 50.5 2.3 0.13 12.4 0.0 4.1 1 1 2 4 4 4 4 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EPS29015.1 - 1.4e-11 44.2 3.5 0.12 12.2 0.0 4.9 3 3 1 4 4 4 3 Ubiquitin-2 like Rad60 SUMO-like DUF2870 PF11069.3 EPS29015.1 - 4.5e-08 33.0 0.0 1.4 8.9 0.0 4.6 4 0 0 4 4 4 3 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 EPS29015.1 - 2e-06 27.6 6.1 4.3 7.3 0.0 4.2 4 0 0 4 4 4 4 GLUT4 regulating protein TUG Methyltrans_RNA PF04452.9 EPS29015.1 - 8.2e-06 25.1 0.2 1.9 7.5 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase FlgD_ig PF13860.1 EPS29015.1 - 5.1e-05 22.9 5.3 13 5.6 0.0 4.3 4 0 0 4 4 4 0 FlgD Ig-like domain Plexin_cytopl PF08337.7 EPS29015.1 - 0.00021 19.7 10.0 2.2 6.5 0.2 5.4 5 2 0 5 5 5 2 Plexin cytoplasmic RasGAP domain Big_3_3 PF13750.1 EPS29015.1 - 0.00093 18.6 0.0 46 3.4 0.0 4.1 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) ACT_4 PF13291.1 EPS29015.1 - 0.0016 18.7 0.6 99 3.3 0.0 4.2 4 0 0 4 4 4 0 ACT domain DUF3861 PF12977.2 EPS29015.1 - 0.0033 17.4 4.6 51 4.0 0.0 4.3 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) CTDII PF01556.13 EPS29015.1 - 0.0044 16.8 12.0 7.1 6.5 0.2 4.4 2 1 2 4 4 4 0 DnaJ C terminal domain Tash_PEST PF07708.6 EPS29015.1 - 0.023 14.5 29.1 3.3 7.7 1.2 4.3 4 0 0 4 4 4 0 Tash protein PEST motif FERM_N PF09379.5 EPS29015.1 - 0.03 14.3 10.5 40 4.3 0.1 5.6 4 3 0 4 4 4 0 FERM N-terminal domain GABP-alpha PF11620.3 EPS29015.1 - 0.28 11.2 9.1 41 4.2 0.1 3.9 3 1 1 4 4 4 0 GA-binding protein alpha chain DUF3781 PF12636.2 EPS29015.1 - 0.35 10.8 7.4 97 3.0 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3781) Myosin_N PF02736.14 EPS29015.1 - 1.6 8.4 8.3 97 2.7 0.1 4.7 4 0 0 4 4 4 0 Myosin N-terminal SH3-like domain CDC48_2 PF02933.12 EPS29015.1 - 7.7 6.2 12.2 66 3.2 0.1 4.1 4 0 0 4 4 4 0 Cell division protein 48 (CDC48), domain 2 BRAP2 PF07576.7 EPS29016.1 - 2.1e-25 88.3 0.0 3.6e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 EPS29016.1 - 2e-19 69.4 6.3 5.9e-19 67.9 4.4 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 EPS29016.1 - 4e-09 36.1 9.9 4e-09 36.1 6.9 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EPS29016.1 - 0.0002 20.9 7.7 0.0002 20.9 5.4 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EPS29016.1 - 0.00088 18.8 5.5 0.00088 18.8 3.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPS29016.1 - 0.0011 18.5 8.8 0.0011 18.5 6.1 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPS29016.1 - 0.0011 18.9 9.7 0.0011 18.9 6.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EPS29016.1 - 0.002 18.1 5.4 0.002 18.1 3.7 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EPS29016.1 - 0.0027 17.3 4.5 0.0067 16.1 1.9 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_6 PF14835.1 EPS29016.1 - 0.012 15.3 3.2 0.012 15.3 2.2 2.2 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EPS29016.1 - 0.015 15.1 5.6 0.038 13.8 3.9 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Occludin_ELL PF07303.8 EPS29016.1 - 0.024 15.3 0.7 0.055 14.2 0.5 1.5 1 0 0 1 1 1 0 Occludin homology domain ApoO PF09769.4 EPS29016.1 - 0.046 13.4 0.1 0.098 12.3 0.1 1.5 1 0 0 1 1 1 0 Apolipoprotein O CCDC92 PF14916.1 EPS29016.1 - 0.095 12.3 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain of unknown function Baculo_RING PF05883.6 EPS29016.1 - 0.29 10.9 1.8 0.68 9.7 1.2 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain Exonuc_VII_L PF02601.10 EPS29016.1 - 0.31 10.1 5.9 0.54 9.3 4.1 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Rootletin PF15035.1 EPS29016.1 - 0.46 10.4 13.9 0.48 10.3 5.8 2.1 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion AATF-Che1 PF13339.1 EPS29016.1 - 0.84 9.7 9.1 1 9.5 5.6 1.7 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor DivIC PF04977.10 EPS29016.1 - 1.5 8.3 3.8 1.3 8.5 0.0 2.4 2 1 0 2 2 2 0 Septum formation initiator bZIP_1 PF00170.16 EPS29016.1 - 1.6 8.7 9.1 0.59 10.1 0.9 2.8 1 1 1 2 2 2 0 bZIP transcription factor DUF342 PF03961.8 EPS29016.1 - 1.9 6.8 4.3 2.8 6.2 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 EPS29016.1 - 2.5 7.0 10.5 3.8 6.4 7.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 EPS29016.1 - 3.5 5.3 4.8 4.8 4.9 3.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 EPS29016.1 - 3.8 7.0 18.1 85 2.6 12.5 2.2 1 1 0 1 1 1 0 IncA protein TMF_DNA_bd PF12329.3 EPS29016.1 - 4.4 7.1 9.9 0.67 9.8 0.4 2.7 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TPR_MLP1_2 PF07926.7 EPS29016.1 - 6.1 6.6 14.9 56 3.4 10.3 2.1 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 EPS29016.1 - 6.5 6.6 15.1 12 5.7 0.8 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Methyltransf_23 PF13489.1 EPS29017.1 - 1.4e-16 60.6 0.0 2.1e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPS29017.1 - 1.6e-11 44.5 0.0 6.5e-06 26.5 0.0 2.5 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EPS29017.1 - 1.2e-10 41.7 0.0 5.2e-10 39.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS29017.1 - 5.7e-09 36.5 0.0 9.3e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPS29017.1 - 4.2e-08 32.9 0.0 0.00099 18.7 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 EPS29017.1 - 1.2e-05 25.6 0.0 0.0001 22.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPS29017.1 - 2.4e-05 24.3 0.0 5.1e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Prp18 PF02840.10 EPS29017.1 - 0.097 12.4 0.2 0.19 11.5 0.2 1.4 1 0 0 1 1 1 0 Prp18 domain Fungal_trans PF04082.13 EPS29018.1 - 1.2e-22 80.1 0.1 2e-22 79.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS29018.1 - 1.2e-08 34.7 11.6 1.2e-08 34.7 8.1 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_31 PF01055.21 EPS29020.1 - 5.1e-167 556.1 3.1 6.8e-167 555.7 2.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EPS29020.1 - 0.026 14.3 0.5 0.11 12.3 0.2 2.3 2 0 0 2 2 2 0 Galactose mutarotase-like GHL15 PF14885.1 EPS29020.1 - 1.5 9.1 5.9 0.13 12.4 0.4 2.1 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase family 15 Zn_clus PF00172.13 EPS29021.1 - 1.7e-06 27.7 8.2 3.2e-06 26.9 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Homeobox_KN PF05920.6 EPS29024.1 - 5.3e-20 70.8 0.3 5.3e-20 70.8 0.2 1.9 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.24 EPS29024.1 - 3.5e-07 29.7 0.1 7.7e-07 28.6 0.1 1.6 1 0 0 1 1 1 1 Homeobox domain Homez PF11569.3 EPS29024.1 - 0.072 12.1 0.3 0.6 9.2 0.0 2.4 2 1 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez P5CR_dimer PF14748.1 EPS29028.1 - 2.9e-37 126.9 1.2 7.1e-37 125.6 0.9 1.7 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EPS29028.1 - 2e-17 63.3 0.2 5e-17 62.1 0.2 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 EPS29028.1 - 4.1e-06 26.6 2.3 5e-05 23.0 1.6 2.2 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 EPS29028.1 - 0.011 15.6 0.1 0.079 12.8 0.0 2.1 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase PDH PF02153.12 EPS29028.1 - 0.04 12.7 0.0 0.07 11.9 0.0 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase Shikimate_DH PF01488.15 EPS29028.1 - 0.16 12.0 1.6 0.33 11.0 0.3 2.3 2 2 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_1 PF00667.15 EPS29029.1 - 3.1e-42 144.5 0.0 4.4e-42 143.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EPS29029.1 - 6.2e-09 36.4 0.0 1.2e-08 35.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Peptidase_S64 PF08192.6 EPS29030.1 - 1.7e-05 23.3 0.0 2.7e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S64 Peptidase_S32 PF05579.8 EPS29030.1 - 0.034 13.1 0.1 0.054 12.4 0.0 1.2 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 bZIP_1 PF00170.16 EPS29031.1 - 0.011 15.6 10.9 0.037 13.9 3.0 2.2 1 1 1 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.10 EPS29031.1 - 1.6 8.5 9.7 11 5.9 6.7 2.0 1 1 0 1 1 1 0 Basic region leucine zipper Methyltransf_31 PF13847.1 EPS29032.1 - 3.7e-31 107.7 0.0 5.1e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPS29032.1 - 5.2e-17 62.1 0.0 9.4e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPS29032.1 - 1.2e-13 51.2 0.0 2e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS29032.1 - 3.9e-13 49.9 0.0 6.5e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPS29032.1 - 7.7e-13 48.0 0.0 1.3e-12 47.3 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 EPS29032.1 - 1.5e-11 44.2 0.0 2.3e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPS29032.1 - 5.2e-09 36.1 0.0 9e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPS29032.1 - 4.9e-08 33.3 0.0 9.8e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EPS29032.1 - 1.4e-07 30.9 0.3 2.1e-07 30.3 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 EPS29032.1 - 2e-06 27.5 0.1 4.4e-06 26.3 0.1 1.6 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 EPS29032.1 - 0.00049 19.2 0.0 0.00072 18.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 EPS29032.1 - 0.0023 17.3 0.0 0.0037 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.13 EPS29032.1 - 0.0034 16.9 0.0 0.0047 16.5 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 DOT1 PF08123.8 EPS29032.1 - 0.0056 16.0 0.1 0.013 14.8 0.0 1.7 1 1 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_3 PF01596.12 EPS29032.1 - 0.021 13.9 0.0 0.097 11.7 0.0 1.9 1 1 0 1 1 1 0 O-methyltransferase Methyltransf_8 PF05148.10 EPS29032.1 - 0.062 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase DUF4152 PF13680.1 EPS29032.1 - 0.078 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4152) Methyltransf_16 PF10294.4 EPS29032.1 - 0.12 11.8 0.1 0.19 11.1 0.1 1.3 1 0 0 1 1 1 0 Putative methyltransferase LMWPc PF01451.16 EPS29033.1 - 1.1e-23 84.1 0.0 1.2e-23 83.9 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase DNA_ligase_OB PF03120.11 EPS29033.1 - 0.056 13.0 0.0 0.097 12.3 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent DNA ligase OB-fold domain Myb_DNA-bind_6 PF13921.1 EPS29035.1 - 2.6e-05 24.2 0.0 5e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain HHH PF00633.18 EPS29036.1 - 0.063 13.0 0.2 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif Ank_2 PF12796.2 EPS29038.1 - 1.6e-155 505.9 6.4 1.2e-22 80.0 0.0 9.1 3 2 7 10 10 10 9 Ankyrin repeats (3 copies) Ank PF00023.25 EPS29038.1 - 2.4e-124 399.4 2.1 3.3e-09 36.0 0.0 15.8 15 0 0 15 15 15 15 Ankyrin repeat Ank_4 PF13637.1 EPS29038.1 - 2.3e-106 346.5 21.2 9.7e-13 48.2 0.1 15.9 3 2 13 16 16 16 14 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPS29038.1 - 1.9e-92 293.7 0.3 1.8e-06 27.6 0.0 16.5 16 0 0 16 16 16 14 Ankyrin repeat Ank_5 PF13857.1 EPS29038.1 - 5.5e-70 229.8 14.1 3.3e-11 43.0 0.5 10.7 6 2 5 11 11 11 10 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.15 EPS29038.1 - 4e-07 29.2 0.0 8.3e-07 28.2 0.0 1.5 1 0 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 EPS29038.1 - 1.5e-06 27.9 0.1 4e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain DUF1296 PF06972.6 EPS29038.1 - 0.0012 18.7 0.0 1.1 9.2 0.0 4.4 4 1 0 4 4 4 1 Protein of unknown function (DUF1296) AAA_22 PF13401.1 EPS29038.1 - 0.0051 16.9 0.0 0.018 15.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EPS29038.1 - 0.086 13.0 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase KAP_NTPase PF07693.9 EPS29038.1 - 0.14 11.1 0.9 2.5 6.9 0.1 2.2 2 0 0 2 2 2 0 KAP family P-loop domain PGA_cap PF09587.5 EPS29038.1 - 0.28 10.5 5.3 42 3.3 0.0 5.8 5 2 1 7 7 7 0 Bacterial capsule synthesis protein PGA_cap RVT_1 PF00078.22 EPS29039.1 - 2.5e-18 66.2 0.0 4.6e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EPS29039.1 - 7.1e-18 64.3 0.9 1.9e-17 62.9 0.1 2.3 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase RNase_H PF00075.19 EPS29039.1 - 4.6e-14 52.8 0.1 1.5e-13 51.2 0.1 2.0 1 0 0 1 1 1 1 RNase H Exo_endo_phos PF03372.18 EPS29039.1 - 4.5e-05 23.5 1.6 0.00011 22.2 1.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF1664 PF07889.7 EPS29039.1 - 0.022 14.5 2.1 0.059 13.1 1.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF972 PF06156.8 EPS29039.1 - 0.022 15.0 0.5 0.52 10.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DivIC PF04977.10 EPS29039.1 - 0.04 13.3 2.5 0.11 11.9 1.7 1.7 1 0 0 1 1 1 0 Septum formation initiator HALZ PF02183.13 EPS29039.1 - 0.05 13.3 0.6 0.12 12.0 0.4 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper GAS PF13851.1 EPS29039.1 - 0.68 9.0 7.5 0.064 12.4 1.0 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding BRE1 PF08647.6 EPS29039.1 - 2.2 8.3 6.7 0.72 9.8 0.9 2.5 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase AAA_16 PF13191.1 EPS29040.1 - 3.6e-05 23.8 0.9 0.0024 17.8 0.4 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EPS29040.1 - 8.9e-05 22.6 0.0 0.0014 18.7 0.0 2.8 3 0 0 3 3 3 1 AAA domain KAP_NTPase PF07693.9 EPS29040.1 - 0.0017 17.4 0.4 0.0088 15.0 0.3 2.0 1 1 0 1 1 1 1 KAP family P-loop domain NACHT PF05729.7 EPS29040.1 - 0.0018 17.9 6.4 0.027 14.1 1.7 3.9 4 1 0 4 4 4 1 NACHT domain PhoU_div PF01865.11 EPS29040.1 - 0.0051 16.0 0.1 0.0095 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF47 NB-ARC PF00931.17 EPS29040.1 - 0.01 14.7 0.0 0.019 13.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 EPS29040.1 - 0.017 15.2 0.0 0.049 13.7 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 EPS29040.1 - 0.03 13.7 0.2 0.1 12.0 0.1 1.9 1 1 1 2 2 2 0 AAA-like domain AAA_18 PF13238.1 EPS29040.1 - 0.032 14.5 0.0 0.12 12.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EPS29040.1 - 0.034 14.0 0.0 0.087 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EPS29040.1 - 0.04 13.6 0.0 0.079 12.6 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase AAA_17 PF13207.1 EPS29040.1 - 0.056 14.2 0.8 0.37 11.6 0.2 2.8 2 1 0 2 2 1 0 AAA domain AAA_29 PF13555.1 EPS29040.1 - 0.087 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain TrwB_AAD_bind PF10412.4 EPS29041.1 - 0.17 10.4 0.1 0.24 9.9 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain APH PF01636.18 EPS29042.1 - 9.2e-13 48.4 0.0 2.8e-12 46.9 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family BCS1_N PF08740.6 EPS29046.1 - 1.3e-34 119.4 0.7 2e-34 118.8 0.5 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EPS29046.1 - 9.1e-17 61.4 0.0 2.1e-16 60.3 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EPS29046.1 - 0.0007 19.0 0.0 0.0022 17.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EPS29046.1 - 0.0097 16.7 0.7 0.074 13.8 0.0 2.8 2 2 0 2 2 2 1 AAA domain KaiC PF06745.8 EPS29046.1 - 0.013 14.6 0.0 0.029 13.4 0.0 1.5 1 0 0 1 1 1 0 KaiC PPV_E1_C PF00519.12 EPS29046.1 - 0.015 13.9 0.0 0.088 11.4 0.0 2.1 2 0 0 2 2 2 0 Papillomavirus helicase AAA_33 PF13671.1 EPS29046.1 - 0.032 14.1 0.0 0.064 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EPS29046.1 - 0.053 13.6 0.0 0.24 11.5 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EPS29046.1 - 0.054 13.2 0.1 0.25 11.0 0.0 2.1 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) IPT PF01745.11 EPS29046.1 - 0.14 11.3 0.0 0.31 10.1 0.0 1.6 1 0 0 1 1 1 0 Isopentenyl transferase AAA_18 PF13238.1 EPS29046.1 - 0.4 10.9 2.0 2.2 8.6 0.1 3.0 2 2 1 3 3 3 0 AAA domain Pkinase PF00069.20 EPS29047.1 - 0.0096 15.0 0.0 0.022 13.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Radial_spoke_3 PF06098.6 EPS29047.1 - 0.073 12.0 6.2 0.22 10.4 4.3 1.8 1 0 0 1 1 1 0 Radial spoke protein 3 Svf1 PF08622.5 EPS29047.1 - 0.1 11.5 0.3 1.5 7.7 0.2 2.1 2 0 0 2 2 2 0 Svf1-like HSDR_N_2 PF13588.1 EPS29047.1 - 0.11 12.2 0.0 0.84 9.4 0.0 2.2 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) TPD PF14811.1 EPS29052.1 - 3.6e-27 94.5 0.0 6.4e-27 93.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function TPD sequence-motif zf-C2H2_jaz PF12171.3 EPS29052.1 - 1.2e-11 44.3 4.6 3e-05 24.0 0.0 2.6 1 1 1 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EPS29052.1 - 4.5e-10 39.3 4.5 1.5e-05 25.0 0.0 3.2 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EPS29052.1 - 0.00045 20.4 7.0 0.063 13.6 0.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EPS29052.1 - 0.0021 18.1 2.1 1.2 9.3 0.0 2.6 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-DBF PF07535.7 EPS29052.1 - 0.015 14.9 3.8 0.1 12.3 1.4 2.4 1 1 1 2 2 2 0 DBF zinc finger zf-C2H2_4 PF13894.1 EPS29052.1 - 0.027 14.7 4.7 0.5 10.8 0.0 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EPS29052.1 - 0.18 11.7 1.0 0.9 9.5 0.0 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger WD40 PF00400.27 EPS29053.1 - 1.6e-79 259.1 34.2 3.5e-13 48.8 0.5 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat NACHT PF05729.7 EPS29053.1 - 9.9e-23 80.6 0.0 1.7e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Nup160 PF11715.3 EPS29053.1 - 9.1e-10 37.2 11.5 0.41 8.7 0.0 6.9 1 1 6 7 7 7 5 Nucleoporin Nup120/160 PD40 PF07676.7 EPS29053.1 - 0.00039 20.0 4.0 2.6 7.8 0.1 5.1 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 EPS29053.1 - 0.00079 18.6 7.7 9.4 5.2 0.0 5.3 1 1 3 5 5 5 2 Neuroblastoma-amplified sequence, N terminal AAA_19 PF13245.1 EPS29053.1 - 0.003 17.2 0.0 0.0075 16.0 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EPS29053.1 - 0.0051 16.8 0.0 0.018 15.0 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Coatomer_WDAD PF04053.9 EPS29053.1 - 0.062 12.0 2.8 4.7 5.9 0.1 2.8 1 1 1 3 3 3 0 Coatomer WD associated region RNA_helicase PF00910.17 EPS29053.1 - 0.078 13.1 0.0 1 9.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Plectin PF00681.15 EPS29053.1 - 0.11 12.0 2.1 51 3.4 0.0 5.1 6 0 0 6 6 6 0 Plectin repeat BIR PF00653.16 EPS29054.1 - 0.00042 20.6 0.1 0.00071 19.9 0.1 1.4 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain Pkinase PF00069.20 EPS29056.1 - 8.6e-13 48.0 0.1 1.8e-12 46.9 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS29056.1 - 1.1e-08 34.5 0.0 2e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PNP_UDP_1 PF01048.15 EPS29056.1 - 2.7e-05 23.2 1.3 0.00022 20.2 0.9 2.2 1 1 0 1 1 1 1 Phosphorylase superfamily HAUS2 PF15003.1 EPS29056.1 - 0.075 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 DUF570 PF04489.8 EPS29056.1 - 0.13 10.5 0.0 0.21 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF570) WD40 PF00400.27 EPS29057.1 - 1.7e-44 148.1 18.0 8.9e-15 53.9 1.1 4.8 4 1 0 4 4 4 4 WD domain, G-beta repeat NACHT PF05729.7 EPS29057.1 - 6.1e-26 91.0 0.0 1.1e-25 90.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain PD40 PF07676.7 EPS29057.1 - 1.8e-08 33.8 6.1 0.43 10.3 0.0 4.6 4 0 0 4 4 4 4 WD40-like Beta Propeller Repeat Nup160 PF11715.3 EPS29057.1 - 0.00053 18.2 0.1 0.045 11.8 0.0 2.5 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 EPS29057.1 - 0.00063 19.5 0.0 0.48 10.0 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A AAA_16 PF13191.1 EPS29057.1 - 0.0043 17.0 0.0 0.028 14.4 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EPS29057.1 - 0.027 14.1 0.0 0.07 12.8 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain IKI3 PF04762.7 EPS29057.1 - 0.043 11.6 2.2 0.23 9.2 1.5 2.0 1 1 0 1 1 1 0 IKI3 family DPPIV_N PF00930.16 EPS29057.1 - 0.53 8.8 4.1 22 3.4 0.0 3.8 2 2 3 5 5 5 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF3435 PF11917.3 EPS29058.1 - 1.3e-151 505.0 4.9 1.8e-151 504.5 3.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) Collagen PF01391.13 EPS29059.1 - 0.032 13.7 0.6 0.052 13.0 0.4 1.2 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) MFS_1 PF07690.11 EPS29061.1 - 5.1e-34 117.5 42.7 5.1e-34 117.5 29.6 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPS29061.1 - 1.7e-12 46.4 12.6 2.1e-12 46.0 8.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FtsH_ext PF06480.10 EPS29061.1 - 0.16 12.1 0.1 0.16 12.1 0.1 2.8 3 0 0 3 3 3 0 FtsH Extracellular Zn_clus PF00172.13 EPS29062.1 - 7.9e-05 22.4 11.0 0.00014 21.6 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MIP-T3 PF10243.4 EPS29064.1 - 2 6.7 17.7 2.3 6.5 12.3 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 HLH PF00010.21 EPS29065.1 - 3.9e-10 39.2 0.1 4.6e-09 35.8 0.0 2.4 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain SPT16 PF08644.6 EPS29065.1 - 0.075 12.8 0.6 0.14 12.0 0.1 1.6 2 0 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) P4Ha_N PF08336.6 EPS29065.1 - 0.092 12.5 0.2 0.22 11.3 0.1 1.6 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region PIF1 PF05970.9 EPS29066.1 - 5.7e-16 58.4 0.0 9e-16 57.7 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EPS29066.1 - 1.8e-09 37.4 0.0 8.5e-09 35.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain Helitron_like_N PF14214.1 EPS29066.1 - 2.8e-08 33.6 0.0 5.2e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus p450 PF00067.17 EPS29067.1 - 7.5e-58 196.1 0.0 2.4e-49 168.1 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 DUF3948 PF13134.1 EPS29067.1 - 0.25 10.8 0.8 0.55 9.7 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3948) p450 PF00067.17 EPS29068.1 - 4.4e-30 104.6 0.0 2.1e-29 102.3 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.23 EPS29069.1 - 3.2e-81 272.8 0.0 5.3e-81 272.1 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EPS29069.1 - 8.7e-76 254.7 0.0 2.2e-75 253.4 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.15 EPS29069.1 - 3.8e-51 173.7 1.8 6.9e-51 172.8 1.3 1.4 1 0 0 1 1 1 1 Condensation domain Acyl_transf_1 PF00698.16 EPS29069.1 - 1.9e-50 171.9 2.7 1.9e-50 171.9 1.8 2.4 3 0 0 3 3 1 1 Acyl transferase domain KR PF08659.5 EPS29069.1 - 6.3e-50 169.3 0.2 5e-49 166.4 0.0 2.5 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 EPS29069.1 - 6.4e-46 156.8 0.1 1.4e-45 155.7 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EPS29069.1 - 2.1e-44 151.3 0.4 3.1e-41 141.0 0.0 2.8 2 0 0 2 2 2 2 short chain dehydrogenase NAD_binding_4 PF07993.7 EPS29069.1 - 9.8e-40 136.0 0.2 6.9e-38 129.9 0.0 3.2 3 1 0 3 3 3 1 Male sterility protein Ketoacyl-synt_C PF02801.17 EPS29069.1 - 3.3e-30 104.3 0.0 1.3e-29 102.5 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Epimerase PF01370.16 EPS29069.1 - 1.4e-19 70.4 0.0 1.2e-16 60.9 0.0 3.0 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family Methyltransf_12 PF08242.7 EPS29069.1 - 3.9e-18 65.7 0.4 3.2e-17 62.8 0.0 2.7 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPS29069.1 - 2.8e-15 56.3 0.0 9.5e-14 51.4 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain HxxPF_rpt PF13745.1 EPS29069.1 - 6.5e-13 48.8 0.0 2.5e-12 46.9 0.0 2.2 1 0 0 1 1 1 1 HxxPF-repeated domain Methyltransf_11 PF08241.7 EPS29069.1 - 6.5e-13 48.9 0.0 2.7e-12 46.9 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EPS29069.1 - 8.8e-13 48.3 5.4 1.7e-07 31.3 0.2 3.3 3 0 0 3 3 2 2 Phosphopantetheine attachment site Methyltransf_31 PF13847.1 EPS29069.1 - 5.2e-11 42.3 0.0 5.6e-10 38.9 0.0 2.6 3 0 0 3 3 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPS29069.1 - 2.2e-09 36.7 0.0 5.1e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EPS29069.1 - 7.5e-09 36.1 0.0 2.4e-07 31.3 0.0 3.6 4 0 0 4 4 2 1 Methyltransferase domain NAD_binding_10 PF13460.1 EPS29069.1 - 1.7e-07 31.4 0.1 5e-06 26.6 0.0 2.7 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 EPS29069.1 - 1.5e-06 27.1 0.0 7.1e-05 21.6 0.0 2.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_16 PF10294.4 EPS29069.1 - 1.5e-05 24.5 0.0 3.5e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Thiolase_N PF00108.18 EPS29069.1 - 2e-05 23.7 0.0 5.4e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_25 PF13649.1 EPS29069.1 - 4.7e-05 23.6 0.0 0.00024 21.4 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EPS29069.1 - 0.00021 20.4 0.0 0.00042 19.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.14 EPS29069.1 - 0.0025 17.3 0.9 0.041 13.4 0.0 2.7 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NodS PF05401.6 EPS29069.1 - 0.016 14.5 0.0 0.041 13.2 0.0 1.6 1 0 0 1 1 1 0 Nodulation protein S (NodS) Polysacc_synt_2 PF02719.10 EPS29069.1 - 0.017 14.0 0.0 1.4 7.7 0.0 2.3 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein DREV PF05219.7 EPS29069.1 - 0.05 12.4 0.0 0.096 11.5 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase Semialdhyde_dh PF01118.19 EPS29069.1 - 0.062 13.5 0.0 0.3 11.3 0.0 2.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain AATase PF07247.7 EPS29069.1 - 0.48 8.9 0.0 0.77 8.2 0.0 1.2 1 0 0 1 1 1 0 Alcohol acetyltransferase 4HBT_2 PF13279.1 EPS29070.1 - 3.5e-08 33.9 0.0 9e-08 32.5 0.0 1.7 1 1 0 1 1 1 1 Thioesterase-like superfamily ADH_zinc_N_2 PF13602.1 EPS29071.1 - 4.5e-22 79.2 0.0 8.5e-22 78.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EPS29071.1 - 6.9e-09 35.3 0.0 1.5e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NmrA PF05368.8 EPS29072.1 - 2.9e-09 36.5 0.1 3.6e-08 32.9 0.1 2.1 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPS29072.1 - 1.8e-07 31.3 0.1 4.7e-07 29.9 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding WD40 PF00400.27 EPS29073.1 - 3.3e-23 80.6 4.5 4.9e-06 26.2 0.0 6.2 7 0 0 7 7 7 4 WD domain, G-beta repeat FmdE PF02663.9 EPS29073.1 - 0.077 12.8 0.0 1.7 8.5 0.0 2.2 2 0 0 2 2 2 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Aminotran_4 PF01063.14 EPS29075.1 - 2e-22 79.8 0.0 2.6e-22 79.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV p450 PF00067.17 EPS29076.1 - 7.5e-74 248.9 0.0 8.9e-74 248.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.2 EPS29078.1 - 1.8e-14 54.1 1.9 1.8e-14 54.1 1.3 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPS29078.1 - 1.1e-12 47.9 0.1 8.8e-12 44.9 0.1 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1100 PF06500.6 EPS29078.1 - 5.2e-10 38.4 0.0 7.4e-10 37.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Esterase PF00756.15 EPS29078.1 - 0.00075 19.0 0.2 0.0022 17.4 0.1 1.7 1 1 0 1 1 1 1 Putative esterase AXE1 PF05448.7 EPS29078.1 - 0.00075 18.0 0.1 0.017 13.6 0.1 2.2 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 EPS29078.1 - 0.00078 18.7 0.1 0.0017 17.6 0.1 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EPS29078.1 - 0.012 15.2 1.0 0.22 11.0 0.5 2.7 2 1 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 EPS29078.1 - 0.042 13.2 0.2 2.8 7.2 0.1 2.6 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Chlorophyllase2 PF12740.2 EPS29078.1 - 0.067 12.0 0.0 0.095 11.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.6 EPS29078.1 - 0.094 11.4 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase BAAT_C PF08840.6 EPS29078.1 - 0.1 12.2 0.0 0.29 10.8 0.0 1.7 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal ADH_zinc_N PF00107.21 EPS29079.1 - 3e-07 30.0 0.0 5.2e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPS29079.1 - 0.00055 19.6 0.0 0.0026 17.5 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EPS29079.1 - 0.025 15.4 0.0 0.042 14.7 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Benyvirus_P25 PF05744.6 EPS29080.1 - 0.072 12.4 0.2 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 Benyvirus P25/P26 protein PALP PF00291.20 EPS29082.1 - 7.7e-61 205.9 0.0 9.7e-61 205.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 EPS29082.1 - 3.2e-06 26.8 0.0 1.9e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 CBS domain adh_short PF00106.20 EPS29083.1 - 5.4e-18 65.4 0.0 9e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPS29083.1 - 2.9e-10 40.1 0.0 4.4e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EPS29083.1 - 0.0015 18.3 0.0 0.0047 16.7 0.0 1.6 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EPS29083.1 - 0.0043 16.0 0.0 0.0065 15.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Zeta_toxin PF06414.7 EPS29083.1 - 0.014 14.5 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Epimerase PF01370.16 EPS29083.1 - 0.026 13.9 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EPS29083.1 - 0.13 12.2 0.1 0.33 10.9 0.1 1.8 1 1 0 1 1 1 0 NADH(P)-binding RNA_helicase PF00910.17 EPS29083.1 - 0.15 12.2 0.0 1.6 8.8 0.0 2.2 2 0 0 2 2 2 0 RNA helicase SRPRB PF09439.5 EPS29084.1 - 9.4e-23 80.3 1.6 3.7e-21 75.1 1.1 2.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 EPS29084.1 - 9.7e-05 21.6 0.3 0.011 15.0 0.0 2.6 2 1 0 2 2 2 1 ADP-ribosylation factor family AAA_16 PF13191.1 EPS29084.1 - 0.00019 21.4 0.3 0.00067 19.7 0.1 2.0 1 1 1 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 EPS29084.1 - 0.00046 20.1 0.0 0.0007 19.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Sigma54_activat PF00158.21 EPS29084.1 - 0.0098 15.3 0.0 1.2 8.6 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_29 PF13555.1 EPS29084.1 - 0.017 14.6 0.2 0.038 13.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EPS29084.1 - 0.038 14.1 0.1 0.077 13.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EPS29084.1 - 0.065 12.6 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.9 EPS29084.1 - 0.081 12.6 0.1 0.14 11.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.12 EPS29084.1 - 0.14 11.6 0.2 6.4 6.2 0.0 2.4 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein GPI-anchored PF10342.4 EPS29085.1 - 6e-06 26.6 0.0 1.5e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family KRE9 PF05390.6 EPS29085.1 - 0.25 11.6 4.7 0.54 10.6 3.3 1.5 1 0 0 1 1 1 0 Yeast cell wall synthesis protein KRE9/KNH1 AA_kinase PF00696.23 EPS29086.1 - 1.3e-38 132.9 0.6 1.9e-38 132.3 0.4 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 EPS29086.1 - 2.8e-18 65.4 0.1 3.6e-17 61.8 0.0 2.4 2 0 0 2 2 2 1 PUA domain Peptidase_M76 PF09768.4 EPS29087.1 - 2.2e-72 242.1 2.5 2.6e-72 241.8 1.7 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.4 EPS29087.1 - 1 8.9 7.7 0.22 11.1 2.1 2.1 1 1 2 3 3 3 0 SprT-like family Pkinase PF00069.20 EPS29088.1 - 1.6e-69 233.9 0.0 2.6e-69 233.2 0.0 1.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS29088.1 - 1.2e-43 149.1 0.0 1.5e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPS29088.1 - 6.9e-07 28.5 0.0 2.2e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EPS29088.1 - 3.5e-05 22.9 0.1 6.4e-05 22.1 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EPS29088.1 - 0.017 14.4 0.2 0.049 12.9 0.1 2.0 2 1 0 2 2 2 0 PhoP regulatory network protein YrbL APH PF01636.18 EPS29088.1 - 0.047 13.4 0.0 0.07 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family TIP41 PF04176.8 EPS29089.1 - 3.9e-81 270.6 0.0 4.7e-81 270.4 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family Orn_Arg_deC_N PF02784.11 EPS29090.1 - 4.2e-33 114.5 0.0 5e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EPS29090.1 - 9.5e-16 57.5 0.0 1.8e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Dak1 PF02733.12 EPS29091.1 - 1.4e-109 365.6 0.1 2e-109 365.1 0.0 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EPS29091.1 - 2.5e-36 124.9 1.0 4.2e-36 124.2 0.7 1.4 1 0 0 1 1 1 1 DAK2 domain DUF3439 PF11921.3 EPS29092.1 - 10 5.9 14.8 15 5.3 10.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Ubiq_cyt_C_chap PF03981.7 EPS29093.1 - 2.1e-36 124.8 0.1 8.1e-36 122.9 0.1 1.8 2 0 0 2 2 2 1 Ubiquinol-cytochrome C chaperone Peptidase_M1 PF01433.15 EPS29094.1 - 5.3e-76 256.2 0.1 6.9e-76 255.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 EPS29094.1 - 1.1e-43 148.2 0.0 2.9e-43 146.8 0.0 1.7 2 0 0 2 2 2 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 EPS29094.1 - 2.4e-17 63.1 0.0 3.8e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M61 PF05299.7 EPS29094.1 - 0.37 10.7 2.3 2.5 8.1 1.6 2.2 1 1 0 1 1 1 0 M61 glycyl aminopeptidase MIT PF04212.13 EPS29096.1 - 3.1e-09 36.5 0.5 7.7e-09 35.3 0.4 1.7 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Zn_clus PF00172.13 EPS29097.1 - 1.9e-08 34.0 7.0 3.3e-08 33.2 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M24 PF00557.19 EPS29099.1 - 5.9e-53 179.5 0.1 8.7e-53 178.9 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EPS29099.1 - 3.8e-28 97.5 0.1 1.1e-27 96.0 0.0 1.8 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain BTB PF00651.26 EPS29100.1 - 0.0019 18.1 0.1 0.0084 16.0 0.0 2.1 2 1 0 2 2 2 1 BTB/POZ domain MBOAT PF03062.14 EPS29101.1 - 5.1e-43 147.4 26.9 5.5e-41 140.7 18.8 3.2 2 1 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family DLH PF01738.13 EPS29102.1 - 1e-30 106.6 0.0 1.2e-30 106.4 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EPS29102.1 - 1.1e-11 44.7 0.0 1.6e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPS29102.1 - 5.7e-06 26.3 0.0 9.3e-05 22.4 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 EPS29102.1 - 0.018 14.1 0.0 0.35 9.8 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) CH PF00307.26 EPS29103.1 - 7.2e-65 215.8 0.0 9.9e-21 73.8 0.2 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 EPS29103.1 - 3.2e-05 23.9 0.4 0.00068 19.7 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair CAMSAP_CH PF11971.3 EPS29103.1 - 6.6e-05 22.4 0.0 0.73 9.5 0.0 3.6 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_6 PF13405.1 EPS29103.1 - 0.015 15.0 1.1 0.32 10.9 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain DDHD PF02862.12 EPS29104.1 - 7.8e-68 228.6 0.0 7.8e-68 228.6 0.0 3.3 2 1 0 2 2 2 1 DDHD domain 4HBT PF03061.17 EPS29105.1 - 7e-14 51.7 0.1 1e-13 51.2 0.1 1.2 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 EPS29105.1 - 0.00058 19.8 0.0 0.00075 19.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) 4HBT_3 PF13622.1 EPS29105.1 - 0.018 14.8 0.1 0.023 14.4 0.1 1.2 1 0 0 1 1 1 0 Thioesterase-like superfamily PXA PF02194.10 EPS29106.1 - 1.2e-39 135.8 0.5 2.9e-39 134.5 0.3 1.7 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.7 EPS29106.1 - 9.2e-25 86.9 0.3 2.3e-23 82.4 0.0 3.1 4 0 0 4 4 4 1 Sorting nexin C terminal PX PF00787.19 EPS29106.1 - 7.4e-09 35.3 0.3 9.3e-08 31.8 0.1 2.5 2 0 0 2 2 2 1 PX domain RGS-like PF09128.6 EPS29106.1 - 0.056 12.9 0.2 1.4 8.4 0.0 2.8 2 1 1 3 3 3 0 Regulator of G protein signalling-like domain PC4 PF02229.11 EPS29107.1 - 3.9e-22 77.2 0.1 6.4e-22 76.5 0.1 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) Hydantoinase_B PF02538.9 EPS29108.1 - 2.1e-206 686.2 0.0 3.1e-206 685.7 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EPS29108.1 - 4.1e-93 311.6 0.0 7.8e-93 310.7 0.0 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EPS29108.1 - 1.4e-56 190.8 1.9 3.2e-55 186.3 0.0 2.7 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase N-terminal region RRM_1 PF00076.17 EPS29109.1 - 1.3e-11 43.9 0.0 1.8e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS29109.1 - 7.7e-08 32.2 0.0 1.2e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS29109.1 - 4e-07 29.7 0.0 5.4e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPS29109.1 - 0.0029 17.3 0.0 0.0042 16.8 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif MIP-T3 PF10243.4 EPS29109.1 - 2.6 6.4 22.6 3.1 6.1 15.7 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Mito_carr PF00153.22 EPS29110.1 - 8.5e-77 252.9 2.7 1.9e-25 88.3 0.0 3.5 4 0 0 4 4 4 3 Mitochondrial carrier protein Tim17 PF02466.14 EPS29110.1 - 0.00047 20.2 0.1 1.3 9.1 0.0 2.7 2 1 0 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family Ribosomal_L18e PF00828.14 EPS29111.1 - 4.5e-25 88.5 0.1 4.5e-25 88.5 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 Aldedh PF00171.17 EPS29112.1 - 5.7e-14 51.2 13.8 4.1e-13 48.4 6.1 2.7 2 1 0 2 2 2 2 Aldehyde dehydrogenase family DUF693 PF05113.8 EPS29112.1 - 0.0083 15.0 0.1 0.015 14.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF693) Polyoma_coat2 PF00761.15 EPS29112.1 - 0.051 13.0 2.6 3.9 6.8 0.2 2.2 2 0 0 2 2 2 0 Polyomavirus coat protein DUF1487 PF07368.6 EPS29112.1 - 0.053 12.7 0.1 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) DUF3383 PF11863.3 EPS29112.1 - 1.7 7.2 8.7 0.044 12.4 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3383) PCI PF01399.22 EPS29113.1 - 0.00021 21.5 0.0 0.0016 18.7 0.0 2.2 2 0 0 2 2 2 1 PCI domain Na_Ca_ex PF01699.19 EPS29116.1 - 8.1e-23 80.5 21.6 3.8e-14 52.4 2.6 2.6 3 0 0 3 3 3 2 Sodium/calcium exchanger protein DUF4173 PF13777.1 EPS29116.1 - 0.046 13.0 0.1 0.046 13.0 0.1 2.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4173) DUF3606 PF12244.3 EPS29117.1 - 0.038 13.6 0.0 0.16 11.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) Macoilin PF09726.4 EPS29117.1 - 0.12 10.6 8.3 0.22 9.7 5.8 1.3 1 0 0 1 1 1 0 Transmembrane protein HAUS-augmin3 PF14932.1 EPS29117.1 - 0.13 11.4 18.6 0.015 14.5 5.4 2.9 2 1 1 3 3 3 0 HAUS augmin-like complex subunit 3 DUF2946 PF11162.3 EPS29120.1 - 2.6 8.2 12.6 0.48 10.6 3.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) Cyclin PF08613.6 EPS29121.1 - 6.3e-33 114.2 0.0 8.6e-33 113.8 0.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EPS29121.1 - 0.0019 17.7 0.1 0.0027 17.2 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ank_2 PF12796.2 EPS29122.1 - 4e-48 161.6 0.4 5.7e-18 65.0 0.1 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) zf-DHHC PF01529.15 EPS29122.1 - 8.6e-40 135.9 4.1 8.6e-40 135.9 2.8 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank PF00023.25 EPS29122.1 - 1e-31 107.1 2.8 8.2e-10 38.0 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 EPS29122.1 - 4.4e-26 90.3 4.0 7e-09 35.6 0.1 5.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPS29122.1 - 4.3e-23 79.0 2.9 6.4e-08 32.1 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 EPS29122.1 - 1.8e-19 69.7 2.6 1.9e-06 28.2 0.1 3.8 1 1 2 4 4 4 4 Ankyrin repeats (many copies) K_oxygenase PF13434.1 EPS29124.1 - 1.3e-111 372.8 0.0 1.5e-111 372.5 0.0 1.0 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EPS29124.1 - 2.5e-11 44.0 0.0 3.8e-10 40.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPS29124.1 - 8.6e-07 28.8 0.0 2.4e-05 24.1 0.0 2.8 2 1 1 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EPS29124.1 - 3.8e-06 26.9 0.0 0.00028 20.8 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Condensation PF00668.15 EPS29125.1 - 4.4e-199 659.4 7.0 2.6e-37 128.3 0.0 7.5 6 2 0 6 6 6 6 Condensation domain AMP-binding PF00501.23 EPS29125.1 - 4.3e-196 651.2 0.0 5.1e-90 301.8 0.0 4.3 4 0 0 4 4 4 4 AMP-binding enzyme PP-binding PF00550.20 EPS29125.1 - 1.1e-56 189.0 19.9 9.4e-11 41.8 0.2 7.5 8 0 0 8 8 8 6 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EPS29125.1 - 6.2e-15 55.9 0.1 9.4e-06 26.4 0.0 3.9 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain Imm1 PF14430.1 EPS29125.1 - 0.066 13.3 0.1 0.89 9.7 0.0 3.0 2 0 0 2 2 2 0 Immunity protein Imm1 HTH_23 PF13384.1 EPS29125.1 - 0.21 11.2 1.2 9.8 5.9 0.0 3.7 4 0 0 4 4 4 0 Homeodomain-like domain Pkinase PF00069.20 EPS29126.1 - 2.7e-43 147.9 0.0 7.4e-43 146.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS29126.1 - 1.4e-26 93.1 0.0 2.7e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPS29126.1 - 0.048 12.6 0.0 0.083 11.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like OB_NTP_bind PF07717.11 EPS29128.1 - 1.2e-28 99.2 0.0 3.8e-28 97.5 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EPS29128.1 - 1.6e-25 89.0 1.7 5.4e-25 87.3 0.0 2.8 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EPS29128.1 - 2.6e-12 46.4 0.0 5.6e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPS29128.1 - 3.4e-05 23.4 0.3 0.00014 21.4 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase T2SE PF00437.15 EPS29128.1 - 5.4e-05 22.2 0.0 0.00011 21.1 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 EPS29128.1 - 7.7e-05 22.8 0.1 0.00046 20.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 EPS29128.1 - 0.0065 16.5 0.0 0.021 14.8 0.0 1.8 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_19 PF13245.1 EPS29128.1 - 0.036 13.8 0.1 0.16 11.7 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain AAA_29 PF13555.1 EPS29128.1 - 0.076 12.5 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EPS29128.1 - 0.16 12.2 0.0 0.16 12.2 0.0 3.4 1 1 1 2 2 2 0 AAA domain Cyt-b5 PF00173.23 EPS29129.1 - 2.9e-21 75.0 0.1 3.2e-21 74.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain V-ATPase_H_C PF11698.3 EPS29129.1 - 0.0075 16.1 0.0 0.0091 15.9 0.0 1.1 1 0 0 1 1 1 1 V-ATPase subunit H EFP_N PF08207.7 EPS29129.1 - 0.073 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain BRX PF08381.6 EPS29129.1 - 0.16 11.0 0.6 0.56 9.3 0.4 2.0 1 1 0 1 1 1 0 Transcription factor regulating root and shoot growth via Pin3 Mcp5_PH PF12814.2 EPS29130.1 - 4.9e-46 155.6 0.0 1.1e-45 154.5 0.0 1.6 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology TPR_MLP1_2 PF07926.7 EPS29130.1 - 0.03 14.0 17.4 0.012 15.3 4.5 2.3 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein GAS PF13851.1 EPS29130.1 - 0.04 13.0 11.1 0.08 12.1 7.7 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.10 EPS29130.1 - 0.084 12.8 17.2 0.17 11.8 11.9 1.4 1 0 0 1 1 1 0 Fez1 CENP-F_leu_zip PF10473.4 EPS29130.1 - 0.19 11.6 12.8 0.34 10.7 8.9 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DDDD PF10161.4 EPS29130.1 - 0.41 10.2 6.9 1.9 8.2 4.8 2.2 1 0 0 1 1 1 0 Putative mitochondrial precursor protein APG6 PF04111.7 EPS29130.1 - 1.9 7.4 10.4 3.3 6.6 7.2 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 HAD_2 PF13419.1 EPS29131.1 - 1.5e-27 96.9 0.0 3e-27 95.9 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPS29131.1 - 1.1e-06 29.1 0.0 2e-06 28.3 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EPS29131.1 - 1.3e-06 28.0 0.0 2.5e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like DUF3920 PF13058.1 EPS29131.1 - 0.098 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3920) FKBP_C PF00254.23 EPS29132.1 - 1.8e-28 98.3 0.0 2.1e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Ras PF00071.17 EPS29134.1 - 1.8e-51 173.7 0.8 1.4e-50 170.8 0.6 1.9 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EPS29134.1 - 4.7e-16 59.3 0.1 1.6e-14 54.4 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EPS29134.1 - 0.00046 19.4 0.2 0.0034 16.6 0.0 1.9 2 0 0 2 2 2 1 ADP-ribosylation factor family FeoB_N PF02421.13 EPS29134.1 - 0.011 14.9 0.4 0.17 11.1 0.0 2.4 2 1 1 3 3 3 0 Ferrous iron transport protein B MMR_HSR1 PF01926.18 EPS29134.1 - 0.012 15.6 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase SRPRB PF09439.5 EPS29134.1 - 0.013 14.7 0.1 0.56 9.4 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_25 PF13481.1 EPS29134.1 - 0.055 12.8 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ser_hydrolase PF06821.8 EPS29134.1 - 0.1 12.2 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase Septin PF00735.13 EPS29134.1 - 0.14 11.1 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Septin I_LWEQ PF01608.12 EPS29135.1 - 0.071 13.0 0.0 0.086 12.7 0.0 1.1 1 0 0 1 1 1 0 I/LWEQ domain AMP-binding PF00501.23 EPS29136.1 - 7.5e-77 258.4 0.0 9.1e-77 258.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPS29136.1 - 1.3e-12 48.4 0.0 5.9e-12 46.3 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Flocculin_t3 PF13928.1 EPS29139.1 - 0.00042 20.4 1.8 0.00042 20.4 1.3 3.2 2 1 1 3 3 3 1 Flocculin type 3 repeat zf-C2H2 PF00096.21 EPS29140.1 - 3.2e-17 61.7 40.4 0.011 15.9 0.2 7.3 7 0 0 7 7 7 7 Zinc finger, C2H2 type zf-met PF12874.2 EPS29140.1 - 5.8e-14 51.7 29.1 6.2e-05 23.0 1.8 6.5 6 0 0 6 6 6 5 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EPS29140.1 - 6.2e-12 45.2 27.5 3.4e-05 23.8 1.4 5.9 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EPS29140.1 - 1.3e-09 38.1 28.9 0.035 14.2 0.8 6.9 1 1 6 7 7 7 5 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 EPS29140.1 - 4.7e-09 35.9 33.6 1.4 9.4 0.2 7.3 7 0 0 7 7 7 6 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EPS29140.1 - 0.00011 22.2 28.0 0.16 12.2 0.5 7.3 7 0 0 7 7 7 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 EPS29140.1 - 0.013 15.3 0.8 0.013 15.3 0.5 6.8 7 0 0 7 7 7 0 C2H2-type zinc finger zf-DBF PF07535.7 EPS29140.1 - 0.22 11.1 13.5 1.1 9.0 1.3 4.2 4 0 0 4 4 4 0 DBF zinc finger zf-DNA_Pol PF08996.5 EPS29140.1 - 0.59 9.4 14.4 0.89 8.8 0.1 3.9 2 1 1 4 4 4 0 DNA Polymerase alpha zinc finger zf-SNAP50_C PF12251.3 EPS29140.1 - 2.6 7.3 12.8 0.075 12.4 1.5 3.0 2 1 1 3 3 3 0 snRNA-activating protein of 50kDa MW C terminal C1_4 PF07975.7 EPS29140.1 - 4.3 7.4 25.1 4.5 7.3 0.8 4.4 3 1 1 4 4 4 0 TFIIH C1-like domain Rad50_zn_hook PF04423.9 EPS29140.1 - 8.4 5.9 9.5 4.8 6.7 0.0 4.3 4 1 1 5 5 5 0 Rad50 zinc hook motif SHMT PF00464.14 EPS29141.1 - 3.2e-200 664.5 0.0 3.8e-200 664.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase MOSC PF03473.12 EPS29142.1 - 2.7e-17 62.4 0.0 4.9e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 EPS29142.1 - 1.5e-15 56.9 0.0 4.2e-14 52.2 0.0 2.3 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain Patatin PF01734.17 EPS29143.1 - 6.6e-28 98.0 0.0 1.3e-27 97.0 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Mg_trans_NIPA PF05653.9 EPS29144.1 - 4e-90 301.8 26.2 5.7e-90 301.3 18.2 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EPS29144.1 - 9.8e-08 32.1 2.1 9.8e-08 32.1 1.4 3.2 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EPS29144.1 - 5.5e-06 26.4 7.0 5.5e-06 26.4 4.8 2.7 2 1 0 2 2 2 1 EamA-like transporter family BRCT PF00533.21 EPS29145.1 - 9.6e-05 22.4 0.0 0.00027 21.0 0.0 1.8 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EPS29145.1 - 0.099 12.5 1.2 0.33 10.8 0.0 2.2 2 0 0 2 2 2 0 twin BRCT domain KilA-N PF04383.8 EPS29146.1 - 0.00027 20.5 0.0 0.0047 16.5 0.0 2.3 1 1 0 1 1 1 1 KilA-N domain HA2 PF04408.18 EPS29148.1 - 2.5e-20 72.4 0.0 6.1e-20 71.1 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EPS29148.1 - 4.5e-13 48.8 0.2 1.7e-12 47.0 0.2 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPS29148.1 - 3.9e-10 39.4 0.1 9.2e-10 38.2 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EPS29148.1 - 2.6e-07 30.8 0.1 1e-06 28.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain OB_NTP_bind PF07717.11 EPS29148.1 - 6.4e-06 25.9 0.0 1.8e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DUF3554 PF12074.3 EPS29149.1 - 1.8e-91 307.0 2.5 8.2e-90 301.6 0.2 4.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3554) HEAT PF02985.17 EPS29149.1 - 8.4e-40 131.2 30.6 0.014 15.4 0.0 20.9 20 0 0 20 20 20 10 HEAT repeat HEAT_2 PF13646.1 EPS29149.1 - 1.1e-37 128.1 47.7 1.8e-09 37.7 0.0 15.4 9 2 6 16 16 16 7 HEAT repeats HEAT_EZ PF13513.1 EPS29149.1 - 6.4e-34 115.5 53.4 1.1e-05 25.7 0.0 23.3 19 4 7 26 26 26 10 HEAT-like repeat Cnd1 PF12717.2 EPS29149.1 - 2.4e-12 47.0 0.2 0.061 13.1 0.0 8.1 6 1 2 9 9 9 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 EPS29149.1 - 2.2e-11 44.0 0.0 2.9 8.3 0.0 8.5 6 2 3 9 9 9 2 Vacuolar 14 Fab1-binding region ParcG PF10274.4 EPS29149.1 - 4.2e-09 36.5 3.7 0.019 14.8 0.0 6.2 5 1 1 6 6 6 2 Parkin co-regulated protein CLASP_N PF12348.3 EPS29149.1 - 1.8e-07 30.7 0.0 0.16 11.3 0.0 5.9 5 1 1 6 6 6 2 CLASP N terminal V-ATPase_H_N PF03224.9 EPS29149.1 - 0.18 10.8 5.7 4 6.4 0.2 3.8 4 1 0 4 4 4 0 V-ATPase subunit H Cohesin_HEAT PF12765.2 EPS29149.1 - 0.25 11.3 11.0 2.1 8.3 0.0 6.6 7 0 0 7 7 7 0 HEAT repeat associated with sister chromatid cohesion Ribosomal_L19e PF01280.15 EPS29150.1 - 9e-61 203.9 9.7 9e-61 203.9 6.7 1.6 1 1 1 2 2 2 1 Ribosomal protein L19e RNase_H2-Ydr279 PF09468.5 EPS29150.1 - 0.045 12.9 0.2 0.048 12.8 0.2 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Endonuc_Holl PF10107.4 EPS29150.1 - 1.7 8.3 5.0 3.6 7.2 3.5 1.6 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Bys1 PF04681.7 EPS29152.1 - 1.2e-10 41.3 0.3 1.4e-10 41.1 0.2 1.1 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Zn_clus PF00172.13 EPS29153.1 - 2e-10 40.3 11.2 2e-10 40.3 7.7 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRN7 PF11781.3 EPS29153.1 - 0.16 11.5 5.4 0.42 10.1 3.8 1.6 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 TPR_12 PF13424.1 EPS29155.1 - 2.7e-38 129.7 7.8 3.7e-16 58.8 0.7 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 EPS29155.1 - 2.2e-33 113.2 1.8 3.2e-07 30.0 0.1 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.23 EPS29155.1 - 6.6e-23 79.3 5.2 0.00022 20.6 0.4 5.6 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 EPS29155.1 - 1.9e-18 64.8 4.9 0.0027 17.4 0.4 5.8 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.1 EPS29155.1 - 1.9e-16 58.4 8.0 0.0056 16.3 0.0 5.6 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_11 PF13414.1 EPS29155.1 - 2.9e-14 52.4 5.1 4.1e-07 29.5 0.1 4.3 2 1 1 4 4 4 3 TPR repeat TPR_14 PF13428.1 EPS29155.1 - 5.9e-13 48.1 7.4 0.094 13.4 0.1 6.2 5 1 1 6 6 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 EPS29155.1 - 2.5e-10 39.3 4.3 0.031 14.0 0.0 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EPS29155.1 - 3.5e-09 37.0 2.8 0.0039 17.8 0.1 4.5 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.9 EPS29155.1 - 2.5e-08 33.5 0.1 2.9 8.5 0.0 5.2 4 0 0 4 4 4 2 Tetratricopeptide repeat NB-ARC PF00931.17 EPS29155.1 - 1.6e-05 23.9 0.0 2.3e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain TPR_19 PF14559.1 EPS29155.1 - 3.3e-05 24.1 11.8 0.05 13.9 0.4 4.7 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 EPS29155.1 - 0.0003 20.7 9.0 5.1 7.5 0.1 6.7 8 1 0 8 8 7 2 Tetratricopeptide repeat Rab5-bind PF09311.6 EPS29155.1 - 0.0063 16.4 0.5 2.1 8.2 0.0 3.4 2 1 1 3 3 3 1 Rabaptin-like protein TPR_6 PF13174.1 EPS29155.1 - 0.03 14.7 6.6 32 5.2 0.1 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat AMP-binding PF00501.23 EPS29156.1 - 7.8e-52 176.0 0.1 1e-51 175.6 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPS29156.1 - 6.2e-09 36.6 0.0 1.4e-08 35.5 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cys_Met_Meta_PP PF01053.15 EPS29157.1 - 8.4e-33 113.1 0.0 1.1e-32 112.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme S-AdoMet_synt_M PF02772.11 EPS29157.1 - 0.16 11.9 0.0 0.33 10.8 0.0 1.5 1 0 0 1 1 1 0 S-adenosylmethionine synthetase, central domain Trp_halogenase PF04820.9 EPS29158.1 - 6.1e-29 100.9 0.0 7e-15 54.5 0.0 2.2 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.14 EPS29158.1 - 1.3e-07 31.0 1.1 6.8e-06 25.3 0.1 2.5 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.9 EPS29158.1 - 5.4e-06 26.4 0.0 9.1e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPS29158.1 - 1.2e-05 25.2 0.1 5.6e-05 23.0 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EPS29158.1 - 1.8e-05 23.8 1.4 4e-05 22.6 0.3 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EPS29158.1 - 7.6e-05 21.9 0.7 0.00017 20.8 0.5 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EPS29158.1 - 0.00048 19.3 0.0 0.11 11.6 0.1 2.4 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 EPS29158.1 - 0.002 17.0 0.0 0.0031 16.4 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 EPS29158.1 - 0.0022 16.5 0.2 0.0094 14.4 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 EPS29158.1 - 0.0028 16.5 0.3 0.0046 15.8 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EPS29158.1 - 0.094 12.7 0.1 0.33 10.9 0.1 1.8 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 EPS29158.1 - 0.1 12.4 0.5 0.4 10.4 0.3 2.0 2 0 0 2 2 2 0 ThiF family Pyr_redox PF00070.22 EPS29158.1 - 0.14 12.5 0.2 0.3 11.5 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EPS29158.1 - 0.15 10.9 0.1 0.3 9.9 0.1 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein 3HCDH_N PF02737.13 EPS29158.1 - 0.16 11.5 0.2 0.34 10.5 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Brr6_like_C_C PF10104.4 EPS29159.1 - 0.00042 19.8 1.0 0.054 13.0 0.0 2.1 1 1 1 2 2 2 2 Di-sulfide bridge nucleocytoplasmic transport domain PSS PF03034.10 EPS29159.1 - 0.85 8.9 4.2 0.1 11.9 0.1 1.6 2 0 0 2 2 2 0 Phosphatidyl serine synthase Glyco_hydro_18 PF00704.23 EPS29160.1 - 1.3e-35 123.4 0.6 4.1e-20 72.5 0.2 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 Mid2 PF04478.7 EPS29163.1 - 0.0017 17.7 0.4 0.003 17.0 0.3 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor MLANA PF14991.1 EPS29163.1 - 0.052 13.5 0.1 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 Protein melan-A adh_short PF00106.20 EPS29164.1 - 7e-26 91.1 2.3 4e-25 88.6 0.7 2.4 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 EPS29164.1 - 7.8e-09 35.4 3.1 2.1e-06 27.5 1.8 3.0 1 1 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EPS29164.1 - 4.9e-05 23.4 0.0 0.00017 21.6 0.0 2.0 2 1 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EPS29164.1 - 0.00079 18.9 0.0 0.0014 18.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EPS29164.1 - 0.03 13.9 0.1 0.16 11.6 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 EPS29164.1 - 0.072 11.9 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain UPF0146 PF03686.8 EPS29164.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) Gly-zipper_Omp PF13488.1 EPS29165.1 - 6.9e-08 32.0 20.7 0.0059 16.2 0.9 5.8 5 0 0 5 5 5 3 Glycine zipper Gly-zipper_OmpA PF13436.1 EPS29165.1 - 0.0074 15.9 20.6 1.8 8.2 0.1 6.0 5 1 0 5 5 5 3 Glycine-zipper containing OmpA-like membrane domain Rick_17kDa_Anti PF05433.10 EPS29165.1 - 2.2 8.0 28.6 1.6 8.4 0.1 5.0 4 0 0 4 4 4 0 Glycine zipper 2TM domain Vasohibin PF14822.1 EPS29166.1 - 4.5 6.2 1.9 15 4.5 1.3 2.0 1 0 0 1 1 1 0 Vasohibin DUF2407 PF10302.4 EPS29167.1 - 0.074 13.2 1.7 0.33 11.1 0.2 2.6 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain Myosin_tail_1 PF01576.14 EPS29168.1 - 8.2e-06 23.8 25.1 1.6e-05 22.8 17.4 1.4 1 0 0 1 1 1 1 Myosin tail TSC22 PF01166.13 EPS29168.1 - 0.00034 20.5 10.6 0.046 13.6 0.4 3.7 3 0 0 3 3 3 2 TSC-22/dip/bun family ADIP PF11559.3 EPS29168.1 - 0.0044 16.9 4.2 0.0044 16.9 2.9 3.1 2 1 0 3 3 2 2 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 EPS29168.1 - 0.011 14.8 11.1 0.015 14.4 1.8 2.4 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Pox_A_type_inc PF04508.7 EPS29168.1 - 0.017 14.8 18.4 0.68 9.8 0.6 4.9 4 0 0 4 4 3 0 Viral A-type inclusion protein repeat bZIP_1 PF00170.16 EPS29168.1 - 0.037 13.9 0.8 0.037 13.9 0.6 4.3 4 1 1 5 5 4 0 bZIP transcription factor PI31_Prot_N PF11566.3 EPS29168.1 - 0.053 13.1 0.8 0.13 11.8 0.5 1.8 1 1 0 1 1 1 0 PI31 proteasome regulator N-terminal Acyl-CoA_dh_C PF12806.2 EPS29168.1 - 0.073 12.9 0.2 0.073 12.9 0.2 2.5 2 0 0 2 2 2 0 Acetyl-CoA dehydrogenase C-terminal like AKNA PF12443.3 EPS29168.1 - 0.076 13.0 9.4 0.91 9.5 1.5 3.1 1 1 0 2 2 2 0 AT-hook-containing transcription factor Bcr-Abl_Oligo PF09036.5 EPS29168.1 - 0.16 11.9 7.6 0.41 10.6 1.0 3.1 3 0 0 3 3 2 0 Bcr-Abl oncoprotein oligomerisation domain GAS PF13851.1 EPS29168.1 - 0.17 11.0 21.7 0.3 10.2 3.1 3.0 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding IZUMO PF15005.1 EPS29168.1 - 0.3 11.1 7.4 1.4 8.9 0.2 3.0 1 1 1 2 2 2 0 Izumo sperm-egg fusion Mnd1 PF03962.10 EPS29168.1 - 0.4 10.3 20.1 0.051 13.2 9.6 2.6 2 1 1 3 3 3 0 Mnd1 family DUF3584 PF12128.3 EPS29168.1 - 0.4 7.9 23.0 0.61 7.3 16.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF948 PF06103.6 EPS29168.1 - 0.45 10.3 3.3 12 5.8 0.1 2.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) FlaC_arch PF05377.6 EPS29168.1 - 0.5 10.3 7.9 2 8.3 0.9 3.4 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) Bacillus_HBL PF05791.6 EPS29168.1 - 0.56 9.5 6.0 0.62 9.4 1.3 2.2 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF4407 PF14362.1 EPS29168.1 - 0.64 8.9 16.4 2 7.3 5.5 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF4446 PF14584.1 EPS29168.1 - 0.7 9.7 11.1 0.17 11.6 2.3 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF4446) PEP-utilisers_N PF05524.8 EPS29168.1 - 0.74 9.6 16.5 3.4 7.4 1.5 3.3 1 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal APG6 PF04111.7 EPS29168.1 - 1.1 8.2 23.8 0.15 11.0 8.8 2.4 1 1 1 2 2 2 0 Autophagy protein Apg6 NPV_P10 PF05531.7 EPS29168.1 - 1.3 9.3 7.6 18 5.6 0.1 4.0 2 1 2 4 4 3 0 Nucleopolyhedrovirus P10 protein TMF_DNA_bd PF12329.3 EPS29168.1 - 1.3 8.8 25.6 0.6 9.9 2.8 4.0 3 1 0 4 4 4 0 TATA element modulatory factor 1 DNA binding Spc7 PF08317.6 EPS29168.1 - 2.6 6.6 24.8 0.014 14.0 9.1 2.6 2 1 1 3 3 3 0 Spc7 kinetochore protein WXG100 PF06013.7 EPS29168.1 - 2.7 8.0 15.1 0.024 14.6 3.5 2.8 3 1 1 4 4 2 0 Proteins of 100 residues with WXG Bap31 PF05529.7 EPS29168.1 - 2.8 7.3 17.7 0.8 9.1 3.6 2.8 3 0 0 3 3 2 0 B-cell receptor-associated protein 31-like Phasin PF05597.6 EPS29168.1 - 3 7.6 13.9 3.6 7.3 6.8 2.8 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Occludin_ELL PF07303.8 EPS29168.1 - 3.1 8.5 10.2 4.8 7.9 1.6 3.3 2 1 1 4 4 3 0 Occludin homology domain DUF4201 PF13870.1 EPS29168.1 - 3.5 7.0 19.2 0.84 9.0 2.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4201) Allexi_40kDa PF05549.6 EPS29168.1 - 4.1 6.6 7.2 4.7 6.4 3.4 2.2 2 1 0 2 2 2 0 Allexivirus 40kDa protein Fib_alpha PF08702.5 EPS29168.1 - 4.5 7.3 19.0 0.18 11.9 3.5 3.3 2 2 1 3 3 3 0 Fibrinogen alpha/beta chain family COG2 PF06148.6 EPS29168.1 - 4.7 7.0 11.9 1.3e+02 2.4 6.9 3.6 2 2 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Baculo_PEP_C PF04513.7 EPS29168.1 - 5 6.9 10.4 0.9 9.3 1.6 2.7 2 1 1 3 3 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ly49 PF08391.5 EPS29168.1 - 5.1 7.2 5.2 1.9 8.6 0.3 2.3 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region DUF2730 PF10805.3 EPS29168.1 - 6.1 6.6 10.4 1.3 8.7 0.7 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2730) DUF3573 PF12097.3 EPS29168.1 - 8.3 4.9 5.2 4.2 5.8 1.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) Fez1 PF06818.10 EPS29168.1 - 8.4 6.3 32.8 11 6.0 18.1 3.0 2 1 0 2 2 2 0 Fez1 Syntaxin PF00804.20 EPS29168.1 - 9.6 6.4 21.2 36 4.5 8.1 4.0 2 1 1 3 3 3 0 Syntaxin CorA PF01544.13 EPS29169.1 - 1.9e-39 135.4 1.5 4.2e-39 134.3 1.0 1.5 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Glyco_hydro_2_C PF02836.12 EPS29171.1 - 6.9e-99 330.4 0.6 9.3e-99 330.0 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.12 EPS29171.1 - 2.5e-52 177.6 0.0 4.3e-52 176.8 0.0 1.3 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.13 EPS29171.1 - 1.3e-48 164.7 0.2 2.3e-48 163.8 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 EPS29171.1 - 2.3e-07 31.2 0.0 9.1e-07 29.3 0.0 2.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_72 PF03198.9 EPS29171.1 - 0.0083 15.1 0.6 0.036 13.0 0.1 2.1 1 1 1 2 2 2 1 Glucanosyltransferase Vac7 PF12751.2 EPS29173.1 - 9e-196 650.2 4.1 1.6e-195 649.4 2.9 1.4 1 0 0 1 1 1 1 Vacuolar segregation subunit 7 DUF3824 PF12868.2 EPS29175.1 - 7.1e-44 150.0 34.3 7.1e-44 150.0 23.8 8.1 4 2 3 8 8 8 2 Domain of unknwon function (DUF3824) DUF3681 PF12442.3 EPS29175.1 - 0.017 15.3 1.0 6 7.0 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3681) DUF2910 PF11139.3 EPS29175.1 - 8.5 5.4 8.7 22 4.0 3.0 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF2910) Cytochrom_B561 PF03188.11 EPS29178.1 - 1.2e-08 34.8 11.6 1.2e-08 34.8 8.0 1.6 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DOMON PF03351.12 EPS29178.1 - 3.3e-05 23.8 1.0 6.5e-05 22.8 0.1 1.8 2 0 0 2 2 2 1 DOMON domain DUF2427 PF10348.4 EPS29178.1 - 0.00023 20.7 5.3 0.00023 20.7 3.7 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) SdpI PF13630.1 EPS29178.1 - 0.00066 19.3 1.7 0.00066 19.3 1.2 2.7 2 1 0 2 2 2 1 SdpI/YhfL protein family DUF1516 PF07457.6 EPS29178.1 - 3.9 7.6 11.2 0.23 11.5 2.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1516) TrbC PF04956.8 EPS29178.1 - 5.9 6.9 19.5 11 6.1 3.8 2.6 2 0 0 2 2 2 0 TrbC/VIRB2 family Copper-bind PF00127.15 EPS29179.1 - 0.0021 18.2 0.1 0.028 14.6 0.1 2.2 1 1 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cu_bind_like PF02298.12 EPS29179.1 - 0.0022 17.7 0.3 0.011 15.5 0.2 2.0 1 1 0 1 1 1 1 Plastocyanin-like domain Cupredoxin_1 PF13473.1 EPS29179.1 - 0.018 14.8 0.0 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 Cupredoxin-like domain Fungal_trans PF04082.13 EPS29180.1 - 1.3e-15 57.0 0.1 1.3e-15 57.0 0.1 2.3 1 1 2 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS29180.1 - 2.9e-07 30.2 7.1 5.3e-07 29.4 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 EPS29180.1 - 1.7 8.8 11.6 0.95 9.6 5.6 2.3 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Sugar_tr PF00083.19 EPS29182.1 - 4.2e-74 249.7 29.0 4.9e-74 249.5 20.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS29182.1 - 9.4e-26 90.3 22.7 9.4e-26 90.3 15.8 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Ribosomal_L44 PF00935.14 EPS29183.1 - 2.5e-34 117.0 12.7 4.2e-34 116.3 8.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L44 ubiquitin PF00240.18 EPS29184.1 - 6.3e-25 86.3 0.0 7e-25 86.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EPS29184.1 - 2.7e-15 55.8 0.0 2.9e-15 55.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EPS29184.1 - 0.00021 21.4 0.0 0.00065 19.9 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain Elongin_A PF06881.6 EPS29185.1 - 5.8e-27 94.2 0.1 8.3e-27 93.7 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A TBCA PF02970.11 EPS29186.1 - 1.5e-23 82.6 12.2 2e-23 82.2 8.5 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A Ribosomal_L29 PF00831.18 EPS29186.1 - 0.0017 18.0 0.4 0.0017 18.0 0.3 2.0 2 1 0 2 2 2 1 Ribosomal L29 protein DUF87 PF01935.12 EPS29186.1 - 0.062 13.1 3.1 0.071 12.9 2.2 1.0 1 0 0 1 1 1 0 Domain of unknown function DUF87 DUF2972 PF11186.3 EPS29186.1 - 0.14 12.0 2.1 0.17 11.7 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2972) DUF4404 PF14357.1 EPS29186.1 - 0.39 11.1 6.9 0.096 13.1 1.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) DUF4315 PF14193.1 EPS29186.1 - 0.59 10.0 9.7 1.3 9.0 6.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4315) DUF2570 PF10828.3 EPS29186.1 - 3 7.4 7.5 2.9 7.5 3.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2570) IncA PF04156.9 EPS29186.1 - 3.1 7.3 13.8 3.4 7.2 9.6 1.1 1 0 0 1 1 1 0 IncA protein HSP70 PF00012.15 EPS29186.1 - 4.3 5.1 10.2 5 4.9 7.1 1.0 1 0 0 1 1 1 0 Hsp70 protein V_ATPase_I PF01496.14 EPS29186.1 - 5.5 4.7 8.1 6.3 4.5 5.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family THOC7 PF05615.8 EPS29187.1 - 9.7e-38 129.5 5.8 9.7e-38 129.5 4.0 2.1 1 1 1 2 2 2 1 Tho complex subunit 7 PilJ PF13675.1 EPS29187.1 - 0.042 14.1 5.4 0.088 13.1 3.8 1.5 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Atg14 PF10186.4 EPS29187.1 - 0.072 12.0 4.6 0.1 11.5 3.2 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 zf-C4H2 PF10146.4 EPS29187.1 - 0.082 12.9 5.2 0.058 13.4 1.7 1.9 1 1 0 2 2 2 0 Zinc finger-containing protein FUSC PF04632.7 EPS29187.1 - 0.093 11.1 3.9 0.12 10.8 2.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family CDC37_N PF03234.9 EPS29187.1 - 0.16 12.3 4.7 0.3 11.3 3.3 1.4 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding DUF4600 PF15372.1 EPS29187.1 - 0.17 12.0 9.9 0.3 11.3 6.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) AAA_23 PF13476.1 EPS29187.1 - 1.1 9.5 6.8 1.8 8.8 4.7 1.4 1 0 0 1 1 1 0 AAA domain DUF342 PF03961.8 EPS29187.1 - 1.7 6.9 5.7 3.5 5.9 4.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF342) V_ATPase_I PF01496.14 EPS29187.1 - 2.2 6.0 3.6 2.9 5.6 2.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RTBV_P46 PF06216.6 EPS29187.1 - 3.8 6.2 5.6 6.5 5.4 0.6 2.1 2 0 0 2 2 2 0 Rice tungro bacilliform virus P46 protein APH PF01636.18 EPS29188.1 - 1.5e-08 34.7 0.0 3e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EPS29188.1 - 0.0036 16.4 0.0 0.022 13.9 0.0 2.0 2 0 0 2 2 2 1 Ecdysteroid kinase DUF1679 PF07914.6 EPS29188.1 - 0.015 13.9 0.0 0.043 12.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) MFS_1 PF07690.11 EPS29189.1 - 5.4e-48 163.5 37.9 4.1e-46 157.3 27.7 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPS29189.1 - 1.6e-15 56.3 19.6 2.2e-15 55.9 13.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EPS29189.1 - 6.1e-11 41.5 12.0 6.1e-11 41.5 8.3 2.7 2 0 0 2 2 2 2 Sugar (and other) transporter Fungal_trans PF04082.13 EPS29190.1 - 7.5e-33 113.4 0.7 1.1e-32 112.9 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS29190.1 - 2.2e-08 33.8 11.6 4.2e-08 32.9 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugarporin_N PF11471.3 EPS29190.1 - 0.0024 17.5 3.0 0.0055 16.3 2.1 1.5 1 0 0 1 1 1 1 Maltoporin periplasmic N-terminal extension Iron_permease PF04120.7 EPS29191.1 - 6.7e-30 103.3 7.9 1.3e-15 57.1 0.0 3.4 3 0 0 3 3 3 3 Low affinity iron permease NicO PF03824.11 EPS29191.1 - 0.00047 19.5 1.4 0.00047 19.5 1.0 2.4 3 0 0 3 3 3 1 High-affinity nickel-transport protein Oxidored_FMN PF00724.15 EPS29192.1 - 1.5e-50 172.1 0.0 3.3e-50 171.0 0.0 1.5 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Malic_M PF03949.10 EPS29193.1 - 4.8e-85 285.1 0.0 6.2e-85 284.8 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EPS29193.1 - 4.6e-63 212.0 0.0 8.1e-63 211.2 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF4449 PF14613.1 EPS29195.1 - 0.0002 21.3 1.1 0.0002 21.3 0.8 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF4449) Tricorn_C1 PF14684.1 EPS29195.1 - 0.00085 19.1 0.4 0.014 15.2 0.2 2.9 3 0 0 3 3 3 1 Tricorn protease C1 domain BRO1 PF03097.13 EPS29195.1 - 0.004 15.9 0.1 0.017 13.8 0.1 2.0 1 1 0 1 1 1 1 BRO1-like domain Lant_dehyd_C PF04738.8 EPS29195.1 - 0.046 11.9 5.0 0.016 13.4 1.1 1.8 2 0 0 2 2 2 0 Lantibiotic dehydratase, C terminus DnaJ PF00226.26 EPS29196.1 - 7.5e-25 86.4 1.6 1.3e-24 85.7 1.1 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EPS29196.1 - 3.6e-17 62.1 14.8 5.9e-17 61.4 10.3 1.4 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 EPS29196.1 - 1.6e-11 43.9 0.0 3.5e-10 39.6 0.0 2.4 2 0 0 2 2 2 1 DnaJ C terminal domain HypA PF01155.14 EPS29196.1 - 0.13 11.9 8.6 0.5 10.0 0.6 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family FYVE_2 PF02318.11 EPS29196.1 - 0.43 10.4 4.9 6.9 6.6 0.1 2.3 2 0 0 2 2 2 0 FYVE-type zinc finger DZR PF12773.2 EPS29196.1 - 6.3 6.7 12.7 7.1e+02 0.1 8.8 2.3 1 1 0 1 1 1 0 Double zinc ribbon Ribosomal_S4 PF00163.14 EPS29197.1 - 5.7e-10 39.4 0.9 9.1e-10 38.7 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EPS29197.1 - 6.4e-05 22.3 0.2 0.00011 21.5 0.1 1.4 1 0 0 1 1 1 1 S4 domain Alk_phosphatase PF00245.15 EPS29198.1 - 2.7e-67 227.3 0.2 4.9e-67 226.4 0.2 1.4 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.18 EPS29198.1 - 1.9e-07 30.5 0.7 3.9e-07 29.5 0.5 1.8 1 1 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EPS29198.1 - 2.2e-06 27.2 0.2 4e-06 26.3 0.1 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EPS29198.1 - 0.00037 19.0 0.3 0.00061 18.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.13 EPS29198.1 - 0.0034 16.8 0.4 0.0077 15.6 0.3 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF1501 PF07394.7 EPS29198.1 - 0.0051 15.6 0.1 0.0087 14.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) FTA4 PF13093.1 EPS29198.1 - 0.008 15.6 0.1 0.012 15.0 0.1 1.2 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Sugar_tr PF00083.19 EPS29201.1 - 1e-84 284.7 17.3 1.2e-84 284.5 12.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS29201.1 - 1.7e-17 63.1 53.8 1.1e-14 53.9 19.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EPS29201.1 - 2e-06 26.4 31.1 0.0025 16.2 5.5 3.6 2 2 2 4 4 4 3 MFS/sugar transport protein Alpha-amylase PF00128.19 EPS29202.1 - 1.5e-96 323.5 0.0 2.1e-96 323.0 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF3459 PF11941.3 EPS29202.1 - 2.4e-05 24.3 0.0 6.9e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3459) Alpha-amylase_C PF02806.13 EPS29202.1 - 0.0048 17.0 0.0 0.02 15.0 0.0 2.1 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Glyco_hydro_42C PF08533.5 EPS29202.1 - 0.0072 15.8 0.0 0.027 13.9 0.0 2.0 1 0 0 1 1 1 1 Beta-galactosidase C-terminal domain hDGE_amylase PF14701.1 EPS29202.1 - 0.015 14.2 0.0 0.027 13.3 0.0 1.3 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Zn_clus PF00172.13 EPS29203.1 - 6.9e-07 29.0 9.9 1.2e-06 28.3 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EPS29203.1 - 5.8e-05 22.0 0.2 9.2e-05 21.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_114 PF03537.8 EPS29205.1 - 1.2e-26 92.2 0.3 2.3e-26 91.3 0.2 1.4 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 CENP-T PF15511.1 EPS29205.1 - 2.2 7.4 28.2 3.1 6.9 19.5 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Hydrolase_6 PF13344.1 EPS29207.1 - 5.1e-22 77.6 0.0 1.1e-21 76.6 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EPS29207.1 - 1e-16 60.4 0.0 2.6e-16 59.0 0.0 1.7 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 EPS29207.1 - 0.0089 16.2 0.0 0.24 11.6 0.0 2.6 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPS29207.1 - 0.013 15.9 0.0 0.15 12.4 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Gly_transf_sug PF04488.10 EPS29208.1 - 5.7e-07 29.8 0.0 1.2e-06 28.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EPS29208.1 - 0.01 14.3 0.0 0.12 10.8 0.0 2.0 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain CAP59_mtransfer PF11735.3 EPS29209.1 - 3.5e-79 265.4 0.0 4.8e-79 264.9 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Virul_fac_BrkB PF03631.10 EPS29209.1 - 0.026 13.9 0.2 0.039 13.2 0.1 1.2 1 0 0 1 1 1 0 Virulence factor BrkB DUF4131 PF13567.1 EPS29209.1 - 0.087 12.2 0.7 0.37 10.1 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) IL13 PF03487.8 EPS29209.1 - 0.16 11.7 0.1 0.79 9.4 0.0 2.1 2 0 0 2 2 2 0 Interleukin-13 PIG-L PF02585.12 EPS29210.1 - 1.4e-21 77.3 0.0 1.9e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Gly_transf_sug PF04488.10 EPS29211.1 - 1.8e-10 41.0 0.0 3.8e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Nuc_sug_transp PF04142.10 EPS29212.1 - 7.6e-19 67.7 10.4 9.8e-19 67.4 7.2 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 EPS29212.1 - 2.3e-08 33.3 6.0 6.4e-08 31.8 3.2 2.3 2 1 0 2 2 2 1 UAA transporter family EmrE PF13536.1 EPS29212.1 - 2.4e-08 34.1 4.9 2.4e-08 34.1 3.4 2.9 2 1 0 2 2 2 1 Multidrug resistance efflux transporter TPT PF03151.11 EPS29212.1 - 0.00062 19.4 2.3 0.00062 19.4 1.6 3.7 2 1 1 3 3 3 2 Triose-phosphate Transporter family EamA PF00892.15 EPS29212.1 - 0.039 13.9 19.1 0.032 14.2 3.6 2.7 2 2 0 2 2 2 0 EamA-like transporter family Glyco_hydro_28 PF00295.12 EPS29213.1 - 3.2e-95 318.8 21.6 4e-95 318.5 15.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EPS29213.1 - 0.03 14.0 40.1 1.4 8.6 27.8 2.9 1 1 0 1 1 1 0 Right handed beta helix region Corona_nucleoca PF00937.13 EPS29214.1 - 0.64 8.9 6.0 0.92 8.3 4.2 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein MFS_1 PF07690.11 EPS29216.1 - 8.7e-39 133.2 27.5 4.3e-38 130.9 17.9 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF4381 PF14316.1 EPS29216.1 - 0.23 11.5 2.4 0.48 10.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF1616 PF07760.6 EPS29216.1 - 2 7.4 13.4 5.2 6.1 3.1 2.8 2 2 1 3 3 3 0 Protein of unknown function (DUF1616) DUF2838 PF10998.3 EPS29216.1 - 4.4 7.2 8.0 1.3 8.9 2.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2838) DUF1201 PF06716.6 EPS29216.1 - 9 6.2 9.1 0.18 11.6 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) OMPdecase PF00215.19 EPS29217.1 - 1.2e-77 260.4 0.0 1.3e-77 260.1 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family MAPEG PF01124.13 EPS29218.1 - 8.2e-26 90.1 0.8 9.6e-26 89.9 0.5 1.0 1 0 0 1 1 1 1 MAPEG family MBOAT PF03062.14 EPS29219.1 - 6.6e-23 81.3 18.7 1.5e-22 80.1 12.9 1.6 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EPS29219.1 - 0.0034 17.4 3.9 0.012 15.6 2.7 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF2293 PF10056.4 EPS29219.1 - 1 9.4 5.0 1.4 8.9 1.2 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2293) WD40 PF00400.27 EPS29220.1 - 3.1e-48 159.9 27.0 1.7e-09 37.1 2.4 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EPS29220.1 - 0.0017 18.1 0.3 0.25 11.0 0.0 2.6 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Bacteroid_pep PF14406.1 EPS29220.1 - 0.077 13.1 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Bacteroidetes Tmemb_170 PF10190.4 EPS29221.1 - 0.00065 19.7 6.8 0.00083 19.3 4.7 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 Tic20 PF09685.5 EPS29221.1 - 5.4 7.0 11.0 2.6 8.0 3.6 2.1 1 1 1 2 2 2 0 Tic20-like protein ICMT PF04140.9 EPS29223.1 - 2.3e-27 95.0 0.1 4.2e-27 94.1 0.1 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EPS29223.1 - 8.8e-13 48.2 2.2 8.8e-13 48.2 1.6 1.8 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 EPS29223.1 - 4.2e-05 22.9 0.4 5.7e-05 22.5 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF161 PF02588.10 EPS29223.1 - 7.5 6.9 8.8 0.2 11.9 0.5 2.4 3 0 0 3 3 3 0 Uncharacterized BCR, YitT family COG1284 Hexapep PF00132.19 EPS29225.1 - 6.6e-14 50.7 3.9 4.6e-11 41.6 1.7 3.1 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EPS29225.1 - 4.2e-13 48.6 4.5 5e-10 38.7 0.7 2.8 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 EPS29225.1 - 1.6e-09 37.6 0.0 2.3e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Maltose acetyltransferase DUF3517 PF12030.3 EPS29226.1 - 1.7e-107 358.9 0.0 3.2e-107 357.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH PF00443.24 EPS29226.1 - 2.2e-47 161.4 0.1 5.7e-47 160.0 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPS29226.1 - 3.7e-18 65.9 0.1 1.3e-17 64.2 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TFIIE_alpha PF02002.12 EPS29228.1 - 5.8e-17 61.1 0.0 1.5e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.7 EPS29228.1 - 0.0086 15.3 1.0 0.022 14.0 0.7 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding NMD3 PF04981.8 EPS29228.1 - 0.027 13.5 0.0 0.053 12.6 0.0 1.4 1 0 0 1 1 1 0 NMD3 family OrfB_Zn_ribbon PF07282.6 EPS29228.1 - 0.085 12.5 0.1 0.2 11.3 0.1 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-FPG_IleRS PF06827.9 EPS29228.1 - 0.3 10.7 1.3 10 5.8 0.2 2.5 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS LEA_6 PF10714.4 EPS29228.1 - 0.38 10.5 4.0 0.16 11.8 0.6 2.0 2 0 0 2 2 2 0 Late embryogenesis abundant protein 18 PseudoU_synth_1 PF01416.15 EPS29229.1 - 2.2e-22 79.4 0.0 8.7e-11 42.1 0.0 2.7 2 0 0 2 2 2 2 tRNA pseudouridine synthase Catalase-rel PF06628.7 EPS29229.1 - 0.25 11.2 1.5 14 5.6 0.0 2.5 2 0 0 2 2 2 0 Catalase-related immune-responsive 2OG-FeII_Oxy_3 PF13640.1 EPS29230.1 - 1.8e-11 44.4 0.0 3.3e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EPS29230.1 - 2.2e-05 24.0 0.1 5.9e-05 22.6 0.1 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Cutinase PF01083.17 EPS29233.1 - 3.3e-54 183.3 5.7 3.8e-54 183.1 3.9 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EPS29233.1 - 1.1e-05 25.0 0.0 1.5e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Lipase_3 PF01764.20 EPS29233.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) MFS_1 PF07690.11 EPS29235.1 - 3.5e-16 58.8 52.2 7.1e-09 34.8 10.7 2.9 1 1 2 3 3 3 2 Major Facilitator Superfamily Cupin_2 PF07883.6 EPS29236.1 - 2.3e-11 43.0 0.1 3.9e-11 42.2 0.1 1.3 1 0 0 1 1 1 1 Cupin domain MannoseP_isomer PF01050.13 EPS29236.1 - 2.1e-05 24.1 0.0 3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase Cupin_1 PF00190.17 EPS29236.1 - 0.0011 18.4 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 Cupin EutQ PF06249.7 EPS29236.1 - 0.0012 18.3 0.0 0.0022 17.5 0.0 1.4 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ AraC_binding PF02311.14 EPS29236.1 - 0.0028 17.3 0.0 0.0043 16.7 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.7 EPS29236.1 - 0.06 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Nitroreductase PF00881.19 EPS29237.1 - 1.2e-14 54.4 0.0 1.4e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family DUF4253 PF14062.1 EPS29237.1 - 0.034 13.7 0.0 0.069 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4253) E1-E2_ATPase PF00122.15 EPS29238.1 - 2.3e-47 160.9 2.9 2.3e-47 160.9 2.0 2.3 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EPS29238.1 - 5.5e-42 143.3 3.5 5.5e-42 143.3 2.4 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EPS29238.1 - 4.6e-30 105.6 0.0 3.3e-29 102.8 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPS29238.1 - 1.4e-23 82.6 0.0 2.7e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EPS29238.1 - 3.5e-14 53.4 0.0 7.7e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EPS29238.1 - 4.1e-09 35.7 0.0 8.8e-09 34.7 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EPS29238.1 - 0.0011 18.6 0.2 0.0021 17.6 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PRRSV_2b PF07069.6 EPS29238.1 - 0.0042 17.3 1.0 0.015 15.5 0.7 1.9 1 0 0 1 1 1 1 Porcine reproductive and respiratory syndrome virus 2b DUF2333 PF10095.4 EPS29238.1 - 0.12 11.0 0.7 0.25 9.9 0.2 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2333) TrkH PF02386.11 EPS29239.1 - 3.1e-94 315.4 11.7 4.1e-90 301.9 3.9 2.1 2 0 0 2 2 2 2 Cation transport protein Chitin_bind_1 PF00187.14 EPS29240.1 - 5.1e-06 26.3 14.3 2.2e-05 24.3 9.1 2.8 2 0 0 2 2 2 1 Chitin recognition protein LysM PF01476.15 EPS29240.1 - 0.00011 21.9 0.0 0.00019 21.2 0.0 1.3 1 0 0 1 1 1 1 LysM domain Mito_fiss_reg PF05308.6 EPS29240.1 - 0.02 14.2 14.7 0.031 13.6 10.2 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator 4HBT_3 PF13622.1 EPS29240.1 - 0.14 11.9 4.2 0.24 11.0 2.9 1.4 1 0 0 1 1 1 0 Thioesterase-like superfamily DUF2360 PF10152.4 EPS29240.1 - 0.58 10.4 4.6 0.83 9.9 3.2 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF605 PF04652.11 EPS29240.1 - 9.4 5.5 14.8 12 5.1 10.2 1.1 1 0 0 1 1 1 0 Vta1 like zf-MYND PF01753.13 EPS29241.1 - 1.2e-09 37.8 18.3 2.3e-09 36.9 12.7 1.5 1 0 0 1 1 1 1 MYND finger SoxD PF04267.7 EPS29241.1 - 0.0096 15.7 0.0 0.025 14.3 0.0 1.7 1 0 0 1 1 1 1 Sarcosine oxidase, delta subunit family PolC_DP2 PF03833.8 EPS29241.1 - 3.2 5.3 5.5 4.1 4.9 3.8 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DEAD PF00270.24 EPS29242.1 - 5e-32 110.7 0.1 1.2e-31 109.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPS29242.1 - 4.8e-15 55.1 0.0 1.7e-14 53.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPS29242.1 - 0.0017 18.2 0.0 0.0034 17.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EPS29242.1 - 0.0051 15.6 0.0 0.011 14.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Anillin PF08174.6 EPS29243.1 - 6.5e-29 100.7 0.4 2e-28 99.2 0.0 2.0 2 0 0 2 2 2 1 Cell division protein anillin PH PF00169.24 EPS29243.1 - 1e-07 32.0 0.0 3.3e-07 30.4 0.0 1.9 1 0 0 1 1 1 1 PH domain Transketolase_N PF00456.16 EPS29244.1 - 6e-21 74.6 1.7 1.3e-19 70.2 1.2 2.1 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.15 EPS29244.1 - 8.4e-13 48.3 0.0 3.7e-12 46.2 0.0 2.0 2 0 0 2 2 2 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.16 EPS29244.1 - 2.7e-06 27.0 1.5 1.1e-05 25.1 1.0 1.9 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Transket_pyr PF02779.19 EPS29244.1 - 0.00022 20.8 0.2 0.00022 20.8 0.1 2.0 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EPS29244.1 - 0.0072 15.0 0.0 0.013 14.2 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component COesterase PF00135.23 EPS29246.1 - 2.1e-79 267.6 0.1 2.7e-79 267.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EPS29246.1 - 1e-05 25.2 0.1 0.00062 19.4 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EPS29246.1 - 0.0095 15.1 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family SET PF00856.23 EPS29247.1 - 9.3e-10 39.0 0.9 3.5e-08 33.9 0.0 3.1 3 0 0 3 3 3 1 SET domain Ribosomal_L14 PF00238.14 EPS29248.1 - 2.7e-44 149.8 2.8 3e-44 149.6 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e TFIIS_C PF01096.13 EPS29249.1 - 1.2e-14 53.5 1.2 1.2e-14 53.5 0.9 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EPS29249.1 - 2.9e-10 39.6 0.7 2.9e-10 39.6 0.5 3.1 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Lar_restr_allev PF14354.1 EPS29249.1 - 0.01 16.0 1.6 0.01 16.0 1.1 2.3 2 1 0 2 2 2 0 Restriction alleviation protein Lar GFA PF04828.9 EPS29249.1 - 0.12 12.2 9.6 0.61 10.0 0.0 2.6 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme zf-AD PF07776.10 EPS29249.1 - 0.14 12.1 0.2 0.14 12.1 0.2 2.6 2 1 0 2 2 2 0 Zinc-finger associated domain (zf-AD) C1_4 PF07975.7 EPS29249.1 - 0.69 9.9 10.8 0.55 10.2 0.6 2.5 2 1 0 2 2 2 0 TFIIH C1-like domain DZR PF12773.2 EPS29249.1 - 2 8.2 15.3 3.6e+03 -2.2 10.6 3.0 1 1 0 1 1 1 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.2 EPS29249.1 - 6.3 6.6 13.9 0.87 9.4 2.2 2.9 2 2 1 3 3 3 0 Transposase zinc-ribbon domain Cytochrome_C7 PF14522.1 EPS29249.1 - 8.6 6.0 9.9 1.1e+02 2.5 6.8 2.3 1 1 0 1 1 1 0 Cytochrome c7 Rotamase PF00639.16 EPS29250.1 - 2.1e-23 82.8 0.1 2.8e-23 82.4 0.1 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EPS29250.1 - 1.2e-16 60.9 0.0 1.5e-16 60.7 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 EPS29250.1 - 1.3e-10 40.8 1.1 3e-10 39.7 0.8 1.6 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.1 EPS29250.1 - 1.4e-06 28.9 0.0 1.7e-06 28.6 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain TACC PF05010.9 EPS29253.1 - 0.00011 21.9 0.4 0.00022 21.0 0.3 1.4 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC) TFIIIC_delta PF12657.2 EPS29253.1 - 0.019 14.6 0.7 0.58 9.8 0.5 2.5 1 1 0 1 1 1 0 Transcription factor IIIC subunit delta N-term RRM_1 PF00076.17 EPS29254.1 - 2.2e-16 59.2 0.0 3.1e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS29254.1 - 6e-12 45.3 0.0 8.5e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS29254.1 - 1.1e-08 34.7 0.0 1.8e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SNO PF01174.14 EPS29255.1 - 2.1e-52 177.4 0.0 1e-42 145.8 0.0 2.0 1 1 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 EPS29255.1 - 1.3e-09 37.8 0.0 7.7e-08 32.0 0.0 2.3 2 1 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 EPS29255.1 - 0.00023 20.7 0.0 0.0033 16.8 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DJ-1_PfpI PF01965.19 EPS29255.1 - 0.00092 18.6 0.0 0.0033 16.9 0.0 1.8 2 0 0 2 2 2 1 DJ-1/PfpI family DUF4066 PF13278.1 EPS29255.1 - 0.0058 15.9 0.0 0.037 13.2 0.0 1.9 2 0 0 2 2 2 1 Putative amidotransferase Peptidase_S51 PF03575.12 EPS29255.1 - 0.071 12.8 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S51 ACPS PF01648.15 EPS29256.1 - 1.1e-09 38.0 0.0 6.2e-09 35.6 0.0 2.1 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily Acyltransferase PF01553.16 EPS29257.1 - 2.2e-34 117.7 0.0 3.8e-34 116.9 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DUF325 PF03804.8 EPS29257.1 - 0.011 15.4 0.1 0.097 12.3 0.0 2.4 3 0 0 3 3 3 0 Viral domain of unknown function TPR_1 PF00515.23 EPS29258.1 - 5.5e-43 142.8 12.0 3.8e-08 32.5 0.0 8.2 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_2 PF07719.12 EPS29258.1 - 1.3e-37 124.6 17.0 4.4e-05 23.0 0.0 9.9 10 0 0 10 10 9 7 Tetratricopeptide repeat TPR_11 PF13414.1 EPS29258.1 - 2.7e-36 123.0 22.9 9.8e-10 37.9 1.8 7.5 5 2 3 8 8 8 7 TPR repeat TPR_8 PF13181.1 EPS29258.1 - 2.2e-26 89.6 0.1 0.0087 15.7 0.0 8.6 8 0 0 8 8 8 7 Tetratricopeptide repeat Apc3 PF12895.2 EPS29258.1 - 3.5e-26 91.1 15.2 1.6e-16 60.1 0.2 4.4 4 0 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EPS29258.1 - 5e-22 78.0 20.8 1.9e-08 34.7 0.0 8.1 7 1 1 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.1 EPS29258.1 - 7.8e-22 77.0 12.8 5.4e-05 23.0 0.1 6.8 5 2 2 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.1 EPS29258.1 - 4.4e-20 70.3 9.3 0.032 14.8 0.0 9.7 7 2 2 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 EPS29258.1 - 2.7e-18 66.0 9.2 2.2e-06 27.9 0.1 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 EPS29258.1 - 1.6e-17 61.8 0.5 0.021 14.5 0.0 7.7 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 EPS29258.1 - 5e-15 54.3 14.4 0.14 12.4 0.0 9.9 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_6 PF13174.1 EPS29258.1 - 1.1e-07 31.7 6.5 2.4 8.7 0.3 8.2 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_9 PF13371.1 EPS29258.1 - 0.00014 21.6 6.3 0.089 12.6 0.1 5.0 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_21 PF09976.4 EPS29258.1 - 0.0029 17.5 0.8 1.1 9.1 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.13 EPS29258.1 - 0.016 15.0 0.2 1.2 9.0 0.1 3.7 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain DUF627 PF04781.7 EPS29258.1 - 0.13 11.9 0.0 0.64 9.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF627) ChAPs PF09295.5 EPS29258.1 - 0.18 10.5 0.5 15 4.2 0.0 2.5 1 1 2 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) APP_E2 PF12925.2 EPS29258.1 - 0.4 10.2 1.5 0.82 9.2 0.1 2.2 2 0 0 2 2 2 0 E2 domain of amyloid precursor protein DUF2225 PF09986.4 EPS29258.1 - 1.4 8.2 5.4 13 5.1 0.0 3.4 2 1 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF788 PF05620.6 EPS29259.1 - 2.6e-45 154.3 0.0 2.9e-45 154.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) CorA PF01544.13 EPS29260.1 - 0.49 9.3 1.4 5.2 6.0 0.1 2.5 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein RINGv PF12906.2 EPS29261.1 - 1.1e-16 60.5 10.2 1.8e-16 59.8 7.1 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 EPS29261.1 - 0.15 11.8 9.2 0.28 11.0 6.4 1.4 1 0 0 1 1 1 0 Ring finger domain zf-Apc11 PF12861.2 EPS29261.1 - 0.93 9.3 3.8 1.9 8.3 2.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 EPS29261.1 - 1.3 9.0 6.0 2.4 8.1 4.2 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 EPS29261.1 - 4.2 7.0 6.4 7.2 6.2 4.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DnaJ_CXXCXGXG PF00684.14 EPS29261.1 - 4.7 7.3 4.8 8.5 6.5 3.3 1.3 1 0 0 1 1 1 0 DnaJ central domain Peptidase_S64 PF08192.6 EPS29262.1 - 0.092 11.0 0.8 0.25 9.6 0.0 1.8 2 0 0 2 2 2 0 Peptidase family S64 Pkinase_Tyr PF07714.12 EPS29262.1 - 0.22 10.5 0.0 0.41 9.6 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase Mur_ligase_M PF08245.7 EPS29263.1 - 3.7e-08 33.6 0.5 7.2e-08 32.6 0.3 1.5 1 1 0 1 1 1 1 Mur ligase middle domain RNase_T PF00929.19 EPS29264.1 - 4.7e-27 95.2 0.0 7.4e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EPS29264.1 - 0.011 15.1 0.0 0.026 13.9 0.0 1.6 1 1 0 1 1 1 0 3'-5' exonuclease HATPase_c PF02518.21 EPS29265.1 - 3.4e-27 94.3 0.0 7.3e-27 93.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EPS29265.1 - 3.4e-24 85.0 1.8 5e-24 84.4 0.3 1.9 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EPS29265.1 - 1.2e-13 50.8 0.0 6.1e-13 48.5 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 EPS29265.1 - 2e-06 27.8 2.4 0.065 13.4 0.0 2.9 2 0 0 2 2 2 2 HAMP domain Cortex-I_coil PF09304.5 EPS29265.1 - 1.5 8.8 6.3 4.7 7.3 0.6 2.5 2 0 0 2 2 2 0 Cortexillin I, coiled coil CMD PF02627.15 EPS29267.1 - 1.3e-12 47.3 0.2 4.9e-10 39.1 0.1 2.4 1 1 0 2 2 2 2 Carboxymuconolactone decarboxylase family ThiF PF00899.16 EPS29268.1 - 9e-43 145.3 0.0 1.6e-42 144.5 0.0 1.4 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 EPS29268.1 - 2.2e-23 81.6 0.3 5.3e-23 80.4 0.2 1.7 1 1 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 EPS29268.1 - 4.2e-08 33.5 0.0 1.3e-07 31.8 0.0 1.8 2 0 0 2 2 2 1 Rhodanese-like domain Shikimate_DH PF01488.15 EPS29268.1 - 0.0026 17.8 0.0 0.012 15.6 0.0 2.2 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ADIP PF11559.3 EPS29268.1 - 0.0084 16.0 1.1 0.014 15.2 0.8 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding NAD_binding_7 PF13241.1 EPS29268.1 - 0.11 12.7 0.0 0.31 11.3 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding SlyX PF04102.7 EPS29268.1 - 0.14 12.5 1.1 0.35 11.2 0.7 1.7 1 0 0 1 1 1 0 SlyX adh_short PF00106.20 EPS29269.1 - 2.6e-25 89.2 2.2 3.7e-25 88.7 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPS29269.1 - 5.6e-19 68.8 0.0 6.8e-19 68.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPS29269.1 - 1.8e-09 37.4 0.8 2.7e-09 36.9 0.5 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EPS29269.1 - 8.2e-05 22.3 0.1 0.00015 21.4 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 EPS29269.1 - 0.0014 18.1 0.2 0.0023 17.4 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EPS29269.1 - 0.0038 16.3 0.2 0.0099 14.9 0.0 1.8 1 1 1 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Saccharop_dh PF03435.13 EPS29269.1 - 0.0065 15.5 0.2 0.0087 15.0 0.2 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 EPS29269.1 - 0.0097 15.9 3.4 0.011 15.7 1.2 2.0 2 1 0 2 2 2 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EPS29269.1 - 0.022 13.6 0.0 0.031 13.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EPS29269.1 - 0.022 14.5 0.9 0.15 11.8 0.1 2.6 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Methyltransf_18 PF12847.2 EPS29269.1 - 0.027 15.0 0.1 0.14 12.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain 3Beta_HSD PF01073.14 EPS29269.1 - 0.049 12.3 0.1 0.35 9.5 0.1 2.1 1 1 2 3 3 3 0 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EPS29269.1 - 0.18 10.6 1.0 0.68 8.7 0.1 2.3 2 1 1 3 3 3 0 RmlD substrate binding domain Gln-synt_C PF00120.19 EPS29270.1 - 1.1e-60 205.0 0.0 1.4e-60 204.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain PALP PF00291.20 EPS29271.1 - 1.2e-61 208.6 0.0 1.4e-61 208.4 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF836 PF05768.9 EPS29272.1 - 2.3e-13 50.1 0.1 2.8e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.1 EPS29272.1 - 0.064 13.4 0.1 0.074 13.2 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain Glutaredoxin PF00462.19 EPS29272.1 - 0.11 12.4 0.1 0.15 12.0 0.1 1.4 1 1 0 1 1 1 0 Glutaredoxin Lipase_3 PF01764.20 EPS29273.1 - 1.4e-08 34.4 0.0 5.9e-08 32.4 0.0 2.0 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EPS29273.1 - 0.034 13.9 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family UPF0227 PF05728.7 EPS29273.1 - 0.07 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) PGAP1 PF07819.8 EPS29273.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF2974 PF11187.3 EPS29273.1 - 0.13 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF4129 PF13559.1 EPS29274.1 - 2.9e-05 23.9 0.0 9.1e-05 22.3 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) NAD_binding_1 PF00175.16 EPS29275.1 - 2.6e-08 34.3 0.0 5.8e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Pyridox_oxidase PF01243.15 EPS29275.1 - 0.00011 22.0 0.0 0.2 11.6 0.0 3.1 3 1 0 3 3 3 2 Pyridoxamine 5'-phosphate oxidase NAD_binding_6 PF08030.7 EPS29275.1 - 0.00014 21.8 0.0 0.0022 17.8 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.19 EPS29275.1 - 0.003 17.6 0.0 0.11 12.6 0.0 2.4 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain Fungal_trans_2 PF11951.3 EPS29276.1 - 1.5e-06 27.1 3.8 4.7e-06 25.4 2.6 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF1875 PF08961.5 EPS29276.1 - 0.013 14.8 2.3 0.022 14.1 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1875) Vps54 PF07928.7 EPS29276.1 - 0.063 13.4 0.1 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Vps54-like protein TPR_11 PF13414.1 EPS29277.1 - 2.4e-12 46.2 1.7 2.4e-12 46.2 1.2 2.1 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.1 EPS29277.1 - 7.7e-07 28.9 1.2 2e-06 27.6 0.9 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 EPS29277.1 - 1.8e-05 24.1 4.3 0.048 13.2 0.0 3.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EPS29277.1 - 0.00011 21.8 0.7 0.52 10.3 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EPS29277.1 - 0.0017 18.0 0.1 0.39 10.6 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EPS29277.1 - 0.0044 17.1 1.8 0.012 15.7 0.6 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EPS29277.1 - 0.0091 15.8 0.2 2.7 7.9 0.0 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EPS29277.1 - 0.03 14.6 2.4 0.034 14.4 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EPS29277.1 - 0.031 14.9 0.6 3.6 8.4 0.0 3.4 2 1 1 3 3 2 0 Tetratricopeptide repeat CAF-1_p150 PF11600.3 EPS29277.1 - 1.2 8.4 8.7 4.6 6.5 0.2 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal BTV_NS2 PF04514.7 EPS29277.1 - 6.4 5.5 7.2 4.2 6.1 0.2 2.1 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 DUF221 PF02714.10 EPS29278.1 - 4.4e-97 324.8 21.8 4.4e-97 324.8 15.1 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EPS29278.1 - 1.2e-42 145.1 0.6 5.9e-42 142.8 0.4 2.3 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EPS29278.1 - 8.8e-21 74.2 2.1 1.5e-20 73.4 1.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_6 PF14259.1 EPS29278.1 - 0.0011 18.8 0.0 0.32 11.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) p450 PF00067.17 EPS29279.1 - 4.2e-70 236.5 0.0 4.8e-70 236.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mito_carr PF00153.22 EPS29280.1 - 4.8e-70 231.3 1.3 2.7e-25 87.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Antimicrobial_8 PF08103.6 EPS29280.1 - 0.11 12.4 1.8 14 5.8 0.0 3.1 3 0 0 3 3 3 0 Uperin family APH PF01636.18 EPS29281.1 - 1.4e-40 139.5 0.0 2.1e-40 138.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EPS29281.1 - 6.2e-06 25.5 0.0 1.6e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.15 EPS29281.1 - 4.5e-05 23.1 0.0 6.7e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 EPS29281.1 - 0.034 13.1 0.0 0.73 8.7 0.0 2.2 1 1 0 1 1 1 0 Fructosamine kinase RIO1 PF01163.17 EPS29281.1 - 0.057 12.7 0.0 8 5.7 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.9 EPS29281.1 - 0.1 11.6 0.0 0.48 9.4 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ank_2 PF12796.2 EPS29282.1 - 3.7e-75 248.3 0.1 6.1e-14 52.1 0.0 6.7 2 1 6 8 8 8 8 Ankyrin repeats (3 copies) Ank PF00023.25 EPS29282.1 - 5.1e-43 142.7 10.1 4.1e-05 23.1 0.0 12.9 13 1 0 13 13 13 9 Ankyrin repeat Ank_4 PF13637.1 EPS29282.1 - 6.3e-43 144.4 6.5 9.1e-09 35.6 0.0 10.5 4 2 6 11 11 11 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPS29282.1 - 4.7e-42 141.0 8.4 1.9e-07 31.1 0.0 10.4 5 1 6 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPS29282.1 - 1.1e-34 115.0 1.7 9.9e-06 25.3 0.0 11.7 13 0 0 13 13 13 8 Ankyrin repeat F-box-like PF12937.2 EPS29282.1 - 0.12 12.1 0.1 0.24 11.1 0.1 1.5 1 0 0 1 1 1 0 F-box-like Porphobil_deam PF01379.15 EPS29283.1 - 7.6e-75 250.5 0.0 1.2e-74 249.9 0.0 1.3 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EPS29283.1 - 2.3e-19 69.2 0.2 5.1e-19 68.1 0.1 1.6 2 0 0 2 2 2 1 Porphobilinogen deaminase, C-terminal domain Ureidogly_hydro PF04115.7 EPS29284.1 - 5.6e-53 178.6 0.0 6.6e-53 178.4 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate hydrolase GTP_EFTU PF00009.22 EPS29285.1 - 3e-48 163.7 0.0 4.7e-48 163.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 EPS29285.1 - 9e-38 128.4 5.8 1.5e-37 127.7 4.0 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 EPS29285.1 - 1.2e-18 66.7 0.0 2.4e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus Ras PF00071.17 EPS29285.1 - 9.4e-06 25.1 0.0 2.5e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 Ras family MMR_HSR1 PF01926.18 EPS29285.1 - 6.1e-05 22.9 0.0 0.00014 21.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.1 EPS29285.1 - 0.0003 20.5 0.0 0.00076 19.2 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EPS29285.1 - 0.00034 20.6 0.3 0.0018 18.3 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 SRPRB PF09439.5 EPS29285.1 - 0.023 13.9 0.0 0.05 12.8 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF1836 PF08876.6 EPS29285.1 - 0.12 12.1 0.2 0.27 10.9 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1836) DUF1882 PF08966.6 EPS29285.1 - 0.12 12.3 0.6 0.3 11.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1882) Snurportin1 PF11538.3 EPS29285.1 - 0.62 9.8 3.1 1 9.1 0.9 2.1 2 0 0 2 2 2 0 Snurportin1 HORMA PF02301.13 EPS29286.1 - 2e-49 167.9 0.1 2.2e-49 167.7 0.0 1.0 1 0 0 1 1 1 1 HORMA domain FlaG PF03646.10 EPS29286.1 - 2.5 8.2 6.2 6.2 7.0 0.5 2.7 2 1 0 2 2 2 0 FlaG protein DUF218 PF02698.12 EPS29287.1 - 6.5e-07 28.9 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain Aldedh PF00171.17 EPS29289.1 - 4.6e-14 51.6 1.6 2.2e-12 46.0 1.1 2.3 1 1 0 1 1 1 1 Aldehyde dehydrogenase family Cupin_2 PF07883.6 EPS29290.1 - 1.4e-09 37.3 0.0 2.5e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 EPS29290.1 - 0.018 14.3 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_1 PF00190.17 EPS29290.1 - 0.085 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Cupin Peptidase_S15 PF02129.13 EPS29291.1 - 1.3e-40 139.5 0.7 1.8e-40 139.1 0.5 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 EPS29291.1 - 5.6e-38 131.0 0.0 9.7e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_5 PF12695.2 EPS29291.1 - 9.6e-05 22.1 0.0 0.00021 21.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPS29291.1 - 0.00056 19.8 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family IN_DBD_C PF00552.16 EPS29291.1 - 0.0088 15.4 0.1 0.022 14.1 0.0 1.6 1 0 0 1 1 1 1 Integrase DNA binding domain Hydrolase_4 PF12146.3 EPS29291.1 - 0.012 15.4 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase FAD_binding_3 PF01494.14 EPS29292.1 - 1.4e-18 67.1 0.2 4.5e-13 48.9 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain ADC PF06314.6 EPS29292.1 - 4.9e-12 45.6 0.0 9.9e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) DAO PF01266.19 EPS29292.1 - 2.7e-10 39.7 0.8 2.6e-05 23.3 0.4 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPS29292.1 - 1.6e-07 31.2 0.4 6.3e-07 29.3 0.2 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EPS29292.1 - 6e-05 23.0 0.2 0.00012 22.0 0.2 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EPS29292.1 - 0.0001 21.3 0.3 0.00018 20.5 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 EPS29292.1 - 0.00019 20.6 0.2 0.043 12.8 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 EPS29292.1 - 0.00053 19.7 0.0 0.0014 18.4 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EPS29292.1 - 0.0014 17.3 0.3 0.27 9.8 0.1 2.4 2 0 0 2 2 2 2 Tryptophan halogenase HI0933_like PF03486.9 EPS29292.1 - 0.0041 15.6 0.1 0.0076 14.7 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 EPS29292.1 - 0.0046 15.8 0.1 0.0072 15.2 0.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 EPS29292.1 - 0.006 16.9 1.9 0.0079 16.5 0.3 2.0 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EPS29292.1 - 0.0085 15.0 0.1 0.17 10.7 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_oxidored PF12831.2 EPS29292.1 - 0.011 14.8 0.2 0.025 13.6 0.1 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.11 EPS29292.1 - 0.025 14.0 0.4 0.05 13.0 0.3 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.12 EPS29292.1 - 0.054 12.5 0.1 0.12 11.4 0.1 1.6 1 0 0 1 1 1 0 Thi4 family HpcH_HpaI PF03328.9 EPS29293.1 - 4.5e-40 136.8 0.0 3.6e-39 133.9 0.0 1.9 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 EPS29293.1 - 2.4e-13 49.6 0.0 8.6e-07 28.0 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold CBP4 PF07960.6 EPS29294.1 - 1.9e-34 118.0 1.6 2.4e-34 117.7 1.1 1.0 1 0 0 1 1 1 1 CBP4 IncA PF04156.9 EPS29294.1 - 0.015 14.9 1.0 0.022 14.3 0.7 1.2 1 0 0 1 1 1 0 IncA protein Trp_oprn_chp PF09534.5 EPS29294.1 - 0.038 13.6 1.1 0.066 12.8 0.0 1.7 1 1 1 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Herpes_UL56 PF04534.7 EPS29294.1 - 0.54 9.9 4.2 0.47 10.1 2.0 1.5 2 0 0 2 2 2 0 Herpesvirus UL56 protein DUF2346 PF09803.4 EPS29294.1 - 4.9 7.0 6.6 6.8 6.6 4.3 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2346) MMtag PF10159.4 EPS29294.1 - 6.8 6.7 11.6 5.9 7.0 7.2 1.5 1 1 0 1 1 1 0 Kinase phosphorylation protein NAD_kinase PF01513.16 EPS29296.1 - 3.5e-44 150.7 0.0 8.1e-44 149.5 0.0 1.4 1 1 0 1 1 1 1 ATP-NAD kinase MaoC_dehydrat_N PF13452.1 EPS29297.1 - 0.0098 15.6 0.0 0.97 9.2 0.0 2.4 2 1 0 2 2 2 2 N-terminal half of MaoC dehydratase Pyridoxal_deC PF00282.14 EPS29298.1 - 1.2e-112 376.1 0.0 1.4e-112 375.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 EPS29298.1 - 9.1e-05 21.7 0.0 0.00015 21.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Sporozoite_P67 PF05642.6 EPS29299.1 - 2.4 5.9 7.1 2.8 5.6 4.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Aa_trans PF01490.13 EPS29300.1 - 2.3e-47 161.4 31.4 2.6e-47 161.2 21.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EPS29300.1 - 0.00089 18.1 14.4 0.00089 18.1 10.0 3.0 2 1 0 3 3 3 1 Tryptophan/tyrosine permease family S1FA PF04689.8 EPS29300.1 - 2.7 7.9 6.1 2.9 7.8 0.0 2.8 3 0 0 3 3 3 0 DNA binding protein S1FA ATP11 PF06644.6 EPS29301.1 - 1e-89 300.6 0.0 1.2e-89 300.3 0.0 1.1 1 0 0 1 1 1 1 ATP11 protein Z1 PF10593.4 EPS29301.1 - 0.16 11.1 0.6 0.27 10.3 0.4 1.3 1 0 0 1 1 1 0 Z1 domain zf-C4H2 PF10146.4 EPS29301.1 - 0.17 11.8 5.2 0.16 11.9 2.8 1.5 1 1 0 1 1 1 0 Zinc finger-containing protein Glyco_hydro_3 PF00933.16 EPS29302.1 - 7.2e-86 287.8 0.0 1e-85 287.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EPS29302.1 - 8.6e-68 228.2 0.0 3.4e-67 226.2 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EPS29302.1 - 3.2e-22 78.2 1.5 1.4e-21 76.2 0.7 2.2 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.7 EPS29302.1 - 2e-17 63.1 0.3 5.2e-17 61.8 0.1 1.8 2 0 0 2 2 2 1 PA14 domain DUF11 PF01345.13 EPS29302.1 - 0.015 15.2 0.3 0.042 13.8 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF11 CARDB PF07705.6 EPS29302.1 - 0.035 14.1 0.0 0.099 12.6 0.0 1.8 1 0 0 1 1 1 0 CARDB AMP-binding PF00501.23 EPS29303.1 - 3.3e-80 269.5 0.1 5.3e-80 268.8 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EPS29303.1 - 4e-75 252.5 0.0 8.2e-75 251.5 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.15 EPS29303.1 - 3.5e-52 177.1 0.5 5.4e-52 176.5 0.3 1.3 1 0 0 1 1 1 1 Condensation domain KR PF08659.5 EPS29303.1 - 1.6e-50 171.2 0.0 5.9e-49 166.1 0.0 2.7 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 EPS29303.1 - 7.2e-48 163.2 0.0 1.2e-47 162.5 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 EPS29303.1 - 4.3e-47 161.0 0.2 7.6e-47 160.1 0.1 1.3 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 EPS29303.1 - 1.7e-44 151.6 0.0 2.7e-40 137.9 0.0 3.3 3 0 0 3 3 3 2 short chain dehydrogenase NAD_binding_4 PF07993.7 EPS29303.1 - 4.6e-39 133.8 0.0 1.3e-38 132.3 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.17 EPS29303.1 - 1.7e-30 105.2 0.0 4.2e-30 104.0 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EPS29303.1 - 7.2e-18 64.6 0.6 8.9e-10 38.6 0.0 3.4 3 0 0 3 3 3 2 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 EPS29303.1 - 2.3e-12 47.2 0.1 9e-12 45.3 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Epimerase PF01370.16 EPS29303.1 - 6.1e-12 45.4 0.0 1.7e-11 44.0 0.0 1.8 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_31 PF13847.1 EPS29303.1 - 4e-11 42.7 0.0 1.5e-10 40.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPS29303.1 - 2.7e-10 40.2 0.0 6e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPS29303.1 - 2.8e-10 40.5 0.0 8.9e-10 38.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain HxxPF_rpt PF13745.1 EPS29303.1 - 8.8e-10 38.7 0.0 3.7e-09 36.7 0.0 2.2 1 0 0 1 1 1 1 HxxPF-repeated domain Methyltransf_18 PF12847.2 EPS29303.1 - 1.4e-08 35.3 0.0 6e-08 33.2 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain 3Beta_HSD PF01073.14 EPS29303.1 - 1e-06 27.6 0.0 3.5e-06 25.9 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ubie_methyltran PF01209.13 EPS29303.1 - 1.9e-05 23.8 0.0 3.7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 EPS29303.1 - 0.00073 18.5 0.0 0.0016 17.5 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.4 EPS29303.1 - 0.00088 18.7 0.0 0.002 17.5 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase NAD_binding_10 PF13460.1 EPS29303.1 - 0.0034 17.4 0.0 0.01 15.8 0.0 1.9 1 0 0 1 1 1 1 NADH(P)-binding MFS_1 PF07690.11 EPS29304.1 - 3.3e-37 128.0 46.5 5.1e-36 124.1 17.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PgaD PF13994.1 EPS29304.1 - 0.28 10.6 3.5 1.4 8.3 0.0 3.2 3 0 0 3 3 3 0 PgaD-like protein DUF3140 PF11338.3 EPS29305.1 - 3.1e-34 116.9 0.3 3.7e-34 116.7 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3140) MerR_1 PF13411.1 EPS29305.1 - 0.14 11.9 0.0 0.7 9.7 0.0 1.9 2 0 0 2 2 2 0 MerR HTH family regulatory protein TauD PF02668.11 EPS29306.1 - 0.0022 17.7 0.0 0.0044 16.7 0.0 1.5 2 0 0 2 2 2 1 Taurine catabolism dioxygenase TauD, TfdA family ADH_zinc_N PF00107.21 EPS29307.1 - 1.1e-09 37.8 0.0 2e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPS29307.1 - 0.00014 21.6 0.0 0.00074 19.2 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Cript PF10235.4 EPS29307.1 - 0.11 12.8 0.2 0.19 12.0 0.1 1.3 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT Zn_clus PF00172.13 EPS29308.1 - 0.00074 19.3 10.0 0.0014 18.4 6.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acyl-CoA_dh_1 PF00441.19 EPS29309.1 - 1.3e-30 106.4 1.3 2.4e-30 105.6 0.9 1.4 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EPS29309.1 - 7.2e-19 67.0 0.2 1.2e-18 66.3 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EPS29309.1 - 7.5e-12 45.6 0.0 1.7e-11 44.5 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EPS29309.1 - 2.6e-06 27.9 0.0 7.3e-06 26.5 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain HpaB_N PF11794.3 EPS29309.1 - 9.7e-05 21.8 0.0 0.00023 20.6 0.0 1.6 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal DUF1540 PF07561.6 EPS29309.1 - 0.12 12.4 0.3 0.31 11.0 0.2 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1540) AA_permease PF00324.16 EPS29310.1 - 8.3e-123 410.2 49.3 1.2e-122 409.7 34.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPS29310.1 - 1.5e-30 106.1 53.4 1.9e-30 105.7 37.0 1.0 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 EPS29312.1 - 2.1e-45 154.9 48.1 1.4e-42 145.6 18.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Zn_clus PF00172.13 EPS29313.1 - 3.5e-07 30.0 11.2 8.4e-07 28.7 7.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.8 EPS29314.1 - 3e-28 98.8 4.8 3e-28 98.8 3.3 1.5 2 0 0 2 2 2 1 RTA1 like protein DUF754 PF05449.6 EPS29314.1 - 0.15 12.1 2.6 8.8 6.4 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF754) DUF3899 PF13038.1 EPS29314.1 - 0.51 10.5 0.0 0.51 10.5 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3899) CTP_transf_1 PF01148.15 EPS29314.1 - 1.1 8.7 19.0 0.25 10.9 0.4 2.1 2 0 0 2 2 2 0 Cytidylyltransferase family OAD_gamma PF04277.8 EPS29314.1 - 1.2 9.5 6.6 10 6.6 0.2 3.7 4 0 0 4 4 4 0 Oxaloacetate decarboxylase, gamma chain DUF2992 PF11208.3 EPS29314.1 - 2.8 7.8 16.2 5.4 6.9 11.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) Pyr_redox_3 PF13738.1 EPS29315.1 - 6.9e-15 55.6 0.0 1.5e-13 51.2 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EPS29315.1 - 2.5e-08 32.6 0.0 1.3e-05 23.5 0.0 3.5 4 0 0 4 4 4 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EPS29315.1 - 1.5e-06 27.4 0.0 0.0039 16.1 0.0 3.2 2 1 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EPS29315.1 - 0.00041 20.3 0.4 1.7 8.6 0.0 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EPS29315.1 - 0.0095 15.8 0.0 4.4 7.1 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EPS29315.1 - 0.16 10.4 0.2 1.9 6.8 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein Rieske PF00355.21 EPS29316.1 - 2.7e-16 58.8 0.0 4.6e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Ring_hydroxyl_A PF00848.14 EPS29316.1 - 4.5e-11 42.8 0.1 1.9e-09 37.4 0.0 2.4 1 1 1 2 2 2 2 Ring hydroxylating alpha subunit (catalytic domain) Fungal_trans PF04082.13 EPS29317.1 - 2.1e-11 43.2 3.1 3.6e-11 42.4 2.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS29317.1 - 2.9e-10 39.8 10.1 8.3e-10 38.4 7.0 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease_2 PF13520.1 EPS29318.1 - 9.7e-45 152.8 55.8 1.2e-44 152.5 38.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPS29318.1 - 9.9e-21 73.6 47.3 1.5e-20 72.9 32.8 1.2 1 0 0 1 1 1 1 Amino acid permease DUF485 PF04341.7 EPS29318.1 - 1.1 8.9 10.9 0.11 12.1 2.0 3.2 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Arylsulfotran_2 PF14269.1 EPS29320.1 - 5.6e-58 196.4 1.2 8.1e-58 195.9 0.9 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EPS29320.1 - 2.5e-15 55.9 1.7 7.8e-15 54.3 1.2 1.8 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Herpes_gE PF02480.11 EPS29320.1 - 0.089 11.0 0.0 0.17 10.0 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E NHL PF01436.16 EPS29320.1 - 4 7.5 5.8 1.1e+02 3.0 0.0 4.2 4 0 0 4 4 4 0 NHL repeat GMC_oxred_C PF05199.8 EPS29321.1 - 7e-31 107.4 0.0 1.2e-30 106.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EPS29321.1 - 1.6e-28 99.7 0.0 1.9e-18 66.6 0.0 3.2 3 0 0 3 3 3 3 GMC oxidoreductase NAD_binding_8 PF13450.1 EPS29321.1 - 0.0024 17.8 0.0 0.0061 16.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EPS29321.1 - 0.021 13.7 0.3 0.033 13.1 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EPS29321.1 - 0.063 13.3 0.0 1.6 8.7 0.0 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HHH PF00633.18 EPS29321.1 - 0.074 12.7 0.5 5.8 6.8 0.0 3.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif FAD_binding_2 PF00890.19 EPS29321.1 - 0.089 11.6 0.3 0.15 10.8 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain CFEM PF05730.6 EPS29322.1 - 2e-14 53.1 14.8 3.9e-14 52.2 10.2 1.5 1 0 0 1 1 1 1 CFEM domain Peroxidase_2 PF01328.12 EPS29324.1 - 4.8e-11 41.8 3.6 7.3e-10 38.0 2.5 2.1 1 1 0 1 1 1 1 Peroxidase, family 2 p450 PF00067.17 EPS29325.1 - 2.2e-71 240.7 0.0 2.6e-71 240.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EPS29327.1 - 7.7e-29 100.4 72.9 1.2e-23 83.3 29.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 EPS29327.1 - 5.9e-06 25.0 16.5 5.9e-06 25.0 11.4 2.4 1 1 2 3 3 3 1 Vacuole effluxer Atg22 like TRAPP PF04051.11 EPS29327.1 - 0.068 12.6 0.2 4.8 6.6 0.0 2.3 2 0 0 2 2 2 0 Transport protein particle (TRAPP) component adh_short PF00106.20 EPS29328.1 - 1e-18 67.8 1.1 2e-18 66.8 0.8 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPS29328.1 - 4.3e-11 42.8 1.3 4.3e-11 42.8 0.9 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EPS29328.1 - 6.1e-05 22.5 0.0 9.1e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RTA1 PF04479.8 EPS29330.1 - 3.4e-50 170.6 8.5 5.3e-50 170.0 5.9 1.2 1 0 0 1 1 1 1 RTA1 like protein bZIP_1 PF00170.16 EPS29331.1 - 3.1e-05 23.8 1.3 6.4e-05 22.8 0.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EPS29331.1 - 0.074 12.8 0.9 0.16 11.8 0.6 1.5 1 0 0 1 1 1 0 Basic region leucine zipper adh_short PF00106.20 EPS29332.1 - 7.7e-26 90.9 0.6 1.1e-25 90.5 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPS29332.1 - 1.7e-19 70.5 0.0 2.4e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 EPS29332.1 - 1.3e-06 27.8 0.3 2.2e-06 27.1 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPS29332.1 - 9.8e-06 25.6 0.2 2.4e-05 24.4 0.1 1.6 2 0 0 2 2 2 1 NADH(P)-binding KR PF08659.5 EPS29332.1 - 4.1e-05 23.3 0.2 7.1e-05 22.5 0.2 1.4 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.21 EPS29332.1 - 0.0029 17.1 1.8 0.025 14.1 1.2 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.16 EPS29332.1 - 0.0065 15.9 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EPS29332.1 - 0.011 15.6 0.1 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain RmlD_sub_bind PF04321.12 EPS29332.1 - 0.068 12.0 0.0 0.092 11.6 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain 2-Hacid_dh_C PF02826.14 EPS29332.1 - 0.1 11.7 0.1 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Antifungal_prot PF11402.3 EPS29334.1 - 2.1e-20 72.6 15.6 2.8e-20 72.2 10.8 1.2 1 0 0 1 1 1 1 Antifungal protein Spheroidin PF05541.7 EPS29334.1 - 0.035 11.7 3.1 0.036 11.6 2.1 1.0 1 0 0 1 1 1 0 Entomopoxvirus spheroidin protein DUF3632 PF12311.3 EPS29335.1 - 4.8e-17 62.3 0.0 4.5e-12 46.1 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3632) DUF3818 PF12825.2 EPS29336.1 - 0.035 12.7 0.3 0.061 11.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) Thiolase_C PF02803.13 EPS29337.1 - 0.15 11.5 5.3 0.024 14.0 1.1 1.7 2 0 0 2 2 2 0 Thiolase, C-terminal domain Cu_amine_oxid PF01179.15 EPS29340.1 - 3.1e-170 566.3 0.5 3.7e-170 566.1 0.3 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EPS29340.1 - 7e-08 32.4 0.1 1.9e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EPS29340.1 - 5e-05 23.2 0.1 9.5e-05 22.4 0.1 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Aldolase_II PF00596.16 EPS29343.1 - 4.6e-48 163.2 0.1 6.1e-48 162.8 0.1 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Lipase_2 PF01674.13 EPS29345.1 - 6.5e-09 35.4 0.0 2.5e-08 33.5 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 2) Abhydrolase_6 PF12697.2 EPS29345.1 - 1.3e-08 35.0 0.0 2.1e-08 34.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPS29345.1 - 2.2e-06 27.4 0.1 3.5e-06 26.8 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPS29345.1 - 0.00022 20.8 0.0 0.00038 20.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.9 EPS29345.1 - 0.0049 16.1 0.0 0.0083 15.4 0.0 1.3 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EPS29345.1 - 0.033 13.7 0.0 0.055 13.0 0.0 1.4 1 1 0 1 1 1 0 PGAP1-like protein DUF915 PF06028.6 EPS29345.1 - 0.071 12.1 0.0 0.69 8.9 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) DUF900 PF05990.7 EPS29345.1 - 0.082 12.2 0.0 0.37 10.0 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) LCAT PF02450.10 EPS29345.1 - 0.13 11.2 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Abhydrolase_2 PF02230.11 EPS29345.1 - 0.13 11.6 0.0 2 7.8 0.0 2.2 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase Zn_clus PF00172.13 EPS29346.1 - 1.3e-05 24.9 13.5 3e-05 23.8 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EPS29346.1 - 0.00031 19.4 0.0 0.0037 15.9 0.0 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EPS29348.1 - 1.4e-33 116.0 30.4 2.1e-33 115.4 21.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily IATP PF04568.7 EPS29350.1 - 3.4e-18 65.4 1.0 4.1e-18 65.2 0.7 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP TMF_DNA_bd PF12329.3 EPS29350.1 - 0.0081 15.9 5.6 0.012 15.3 3.9 1.4 1 1 0 1 1 1 1 TATA element modulatory factor 1 DNA binding Atg14 PF10186.4 EPS29350.1 - 0.055 12.4 1.4 0.057 12.3 0.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4200 PF13863.1 EPS29350.1 - 0.19 11.7 7.8 0.26 11.2 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF4446 PF14584.1 EPS29350.1 - 0.19 11.5 1.5 0.24 11.2 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) HR1 PF02185.11 EPS29350.1 - 0.21 11.3 5.7 0.66 9.7 3.9 1.9 1 1 0 1 1 1 0 Hr1 repeat ABC2_membrane PF01061.19 EPS29351.1 - 1.3e-91 305.4 43.5 1.2e-49 168.3 11.7 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 EPS29351.1 - 5.2e-42 143.4 0.0 2.2e-19 70.0 0.0 3.4 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 EPS29351.1 - 1.1e-29 102.1 6.3 5.9e-28 96.5 0.0 3.1 3 0 0 3 3 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 EPS29351.1 - 3e-13 49.5 28.5 1.8e-08 33.7 7.6 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 EPS29351.1 - 1.4e-05 24.5 0.4 0.0077 15.6 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EPS29351.1 - 0.0003 20.9 0.3 0.067 13.3 0.0 3.1 3 1 0 3 3 2 1 AAA domain AAA_29 PF13555.1 EPS29351.1 - 0.00037 19.9 1.4 0.094 12.2 0.2 2.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 EPS29351.1 - 0.00052 19.2 0.3 0.016 14.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EPS29351.1 - 0.00089 19.2 0.7 0.22 11.5 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 EPS29351.1 - 0.0022 18.2 0.1 2.4 8.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EPS29351.1 - 0.0032 18.2 0.0 1.3 9.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain ABC_trans_N PF14510.1 EPS29351.1 - 0.0038 17.2 0.1 0.0099 15.9 0.1 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_28 PF13521.1 EPS29351.1 - 0.0067 16.4 2.4 0.4 10.6 0.5 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EPS29351.1 - 0.01 15.6 0.6 2.1 8.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.1 EPS29351.1 - 0.02 14.8 0.0 0.81 9.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain cobW PF02492.14 EPS29351.1 - 0.066 12.6 2.5 0.32 10.4 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 EPS29351.1 - 0.076 12.9 0.1 12 5.9 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_19 PF13245.1 EPS29351.1 - 0.13 12.0 0.3 18 5.1 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain PduV-EutP PF10662.4 EPS29351.1 - 0.17 11.3 0.8 1.4 8.4 0.2 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 EPS29351.1 - 0.19 11.3 1.5 2.2 7.9 0.2 2.3 2 0 0 2 2 2 0 NACHT domain TspO_MBR PF03073.10 EPS29353.1 - 1.8e-46 157.3 9.2 2.1e-46 157.0 6.4 1.1 1 0 0 1 1 1 1 TspO/MBR family DUF1212 PF06738.7 EPS29354.1 - 5.6e-56 189.0 15.4 1e-51 175.1 0.3 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EPS29354.1 - 1.7e-28 99.1 9.5 1.7e-28 99.1 6.6 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF3815) Asparaginase_II PF06089.7 EPS29355.1 - 1.4e-107 359.1 0.0 1.6e-107 358.9 0.0 1.0 1 0 0 1 1 1 1 L-asparaginase II HNH_2 PF13391.1 EPS29356.1 - 0.047 13.4 0.1 0.1 12.3 0.1 1.5 1 1 0 1 1 1 0 HNH endonuclease Ank_2 PF12796.2 EPS29357.1 - 1e-18 67.4 0.3 6.2e-09 36.0 0.1 2.6 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPS29357.1 - 8.2e-11 42.1 0.3 0.0054 17.2 0.0 3.8 2 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.25 EPS29357.1 - 3.6e-09 35.9 7.1 0.018 14.8 0.1 5.8 5 1 1 6 6 6 3 Ankyrin repeat Ank_3 PF13606.1 EPS29357.1 - 1.2e-07 31.2 0.8 0.98 9.8 0.1 5.5 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.1 EPS29357.1 - 7.9e-07 29.1 0.9 0.0009 19.4 0.1 3.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) DDE_1 PF03184.14 EPS29358.1 - 1.1e-17 63.8 0.0 2.5e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease PrkA PF06798.7 EPS29358.1 - 0.12 11.5 0.0 6.5 5.9 0.0 2.2 2 0 0 2 2 2 0 PrkA serine protein kinase C-terminal domain Acetyltransf_7 PF13508.1 EPS29360.1 - 1.5e-08 34.6 0.0 2.6e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPS29360.1 - 1.6e-07 31.2 0.0 2.8e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EPS29360.1 - 2.5e-05 24.3 0.2 0.00021 21.4 0.0 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPS29360.1 - 6.5e-05 22.7 0.0 0.0001 22.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPS29360.1 - 0.00014 21.5 0.0 0.00027 20.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EPS29360.1 - 0.022 14.6 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EPS29360.1 - 0.16 11.8 0.0 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Cellulase PF00150.13 EPS29361.1 - 8.6e-16 57.9 7.9 1.3e-15 57.4 5.5 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Fungal_trans PF04082.13 EPS29362.1 - 2e-12 46.5 1.0 3.9e-12 45.5 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS29362.1 - 2e-09 37.1 9.9 2e-09 37.1 6.9 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mak10 PF04112.8 EPS29363.1 - 4.9e-56 188.5 0.0 8.3e-56 187.8 0.0 1.4 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase ATP-synt_Eps PF04627.8 EPS29364.1 - 4.6e-24 83.7 3.9 7.5e-24 83.0 2.7 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain ApoO PF09769.4 EPS29364.1 - 0.12 12.0 0.1 0.13 11.9 0.0 1.0 1 0 0 1 1 1 0 Apolipoprotein O Myc_N PF01056.13 EPS29365.1 - 0.0078 15.4 7.7 0.019 14.1 5.3 1.7 1 1 0 1 1 1 1 Myc amino-terminal region Daxx PF03344.10 EPS29365.1 - 0.01 14.3 8.7 0.012 14.1 6.1 1.1 1 0 0 1 1 1 0 Daxx Family NABP PF07990.7 EPS29365.1 - 0.023 13.9 0.2 0.032 13.5 0.2 1.2 1 0 0 1 1 1 0 Nucleic acid binding protein NABP Nop14 PF04147.7 EPS29365.1 - 0.047 11.6 10.3 0.058 11.3 7.2 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.7 EPS29365.1 - 0.049 13.3 11.0 0.068 12.8 7.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop53 PF07767.6 EPS29365.1 - 0.12 11.2 8.0 0.19 10.6 5.5 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) CDC45 PF02724.9 EPS29365.1 - 0.43 8.5 12.0 0.62 8.0 8.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.8 EPS29365.1 - 0.53 7.9 21.2 0.86 7.3 14.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi Nucleoplasmin PF03066.10 EPS29365.1 - 0.99 8.9 16.4 2.2 7.8 11.4 1.5 1 0 0 1 1 1 0 Nucleoplasmin Sigma70_ner PF04546.8 EPS29365.1 - 1.6 8.3 10.0 2.7 7.5 6.9 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region NOA36 PF06524.7 EPS29365.1 - 1.9 7.6 13.1 3.6 6.7 9.1 1.4 1 0 0 1 1 1 0 NOA36 protein Cpn60_TCP1 PF00118.19 EPS29366.1 - 4.5e-117 391.6 5.6 5.2e-117 391.4 3.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1547 PF07577.6 EPS29366.1 - 0.11 12.2 1.4 0.49 10.1 0.2 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1547) Phosphoesterase PF04185.9 EPS29367.1 - 5.3e-32 111.4 5.5 2.2e-31 109.4 3.8 1.8 1 1 0 1 1 1 1 Phosphoesterase family Big_3_4 PF13754.1 EPS29367.1 - 0.74 10.1 9.5 0.21 11.9 3.9 2.1 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) HAMP PF00672.20 EPS29368.1 - 1.5e-35 121.2 12.8 1.8e-09 37.6 0.2 6.0 5 0 0 5 5 5 5 HAMP domain HATPase_c PF02518.21 EPS29368.1 - 1.7e-29 101.7 0.1 4.4e-29 100.4 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EPS29368.1 - 1.6e-27 95.7 1.3 3.6e-27 94.5 0.5 2.0 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EPS29368.1 - 1e-17 63.8 1.3 7.2e-17 61.1 0.1 3.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain AAA_13 PF13166.1 EPS29368.1 - 0.025 13.0 5.5 0.2 10.0 0.2 2.8 2 1 0 3 3 3 0 AAA domain DUF2200 PF09966.4 EPS29368.1 - 0.04 13.7 0.4 42 4.0 0.0 3.9 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2200) DUF948 PF06103.6 EPS29368.1 - 0.6 10.0 22.8 0.28 11.0 0.3 6.0 3 2 1 5 5 5 0 Bacterial protein of unknown function (DUF948) DUF2365 PF10157.4 EPS29368.1 - 0.99 9.2 11.3 6.1 6.7 0.2 4.7 5 2 0 5 5 5 0 Uncharacterized conserved protein (DUF2365) DASH_Dad2 PF08654.5 EPS29368.1 - 2.1 8.4 7.9 3.9 7.5 0.1 4.5 4 1 1 5 5 5 0 DASH complex subunit Dad2 CorA PF01544.13 EPS29369.1 - 2.6e-08 33.2 3.0 2.7e-08 33.2 0.4 2.1 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF676 PF05057.9 EPS29369.1 - 7.1e-06 25.4 0.0 1.4e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EPS29369.1 - 0.012 15.4 0.1 0.084 12.7 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family PGAP1 PF07819.8 EPS29369.1 - 0.014 15.0 0.0 0.046 13.2 0.0 1.9 2 0 0 2 2 2 0 PGAP1-like protein 7TM_GPCR_Srab PF10292.4 EPS29369.1 - 0.29 9.7 0.1 0.46 9.1 0.1 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor Mito_carr PF00153.22 EPS29370.1 - 1.4e-62 207.4 3.3 1.1e-20 73.1 0.0 4.1 3 1 0 3 3 3 3 Mitochondrial carrier protein F-box-like PF12937.2 EPS29371.1 - 1.2e-09 37.7 0.2 2.8e-09 36.5 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EPS29371.1 - 0.00012 21.6 0.0 0.00026 20.5 0.0 1.5 1 0 0 1 1 1 1 F-box domain TPR_2 PF07719.12 EPS29371.1 - 0.0019 17.9 0.3 0.92 9.5 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EPS29371.1 - 0.013 15.1 0.1 0.88 9.2 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat MIT PF04212.13 EPS29371.1 - 0.019 14.8 0.3 0.034 14.0 0.2 1.3 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_11 PF13414.1 EPS29371.1 - 0.026 14.1 0.4 0.067 12.8 0.2 1.6 1 1 0 1 1 1 0 TPR repeat Mucin PF01456.12 EPS29371.1 - 2.1 8.1 5.6 3.9 7.2 3.9 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Aa_trans PF01490.13 EPS29372.1 - 5.5e-40 137.1 34.7 6.4e-40 136.8 24.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PAS_9 PF13426.1 EPS29373.1 - 1.3e-21 76.9 0.0 1.1e-17 64.3 0.0 2.5 2 0 0 2 2 2 2 PAS domain PAS PF00989.19 EPS29373.1 - 1e-06 28.4 0.0 0.0035 17.1 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.5 EPS29373.1 - 0.0037 17.2 0.0 1.6 8.8 0.0 2.7 3 0 0 3 3 3 2 PAS fold PAS_3 PF08447.6 EPS29373.1 - 0.0083 16.1 0.3 4 7.6 0.0 2.9 3 0 0 3 3 3 2 PAS fold OB_NTP_bind PF07717.11 EPS29374.1 - 1.5e-20 73.1 0.0 3.1e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EPS29374.1 - 1.5e-17 63.4 0.2 3.6e-17 62.2 0.2 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EPS29374.1 - 8.5e-13 47.9 0.0 3.7e-12 45.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPS29374.1 - 0.00086 18.8 0.0 0.0052 16.2 0.0 2.2 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_29 PF13555.1 EPS29374.1 - 0.0024 17.3 0.0 0.0057 16.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EPS29374.1 - 0.016 15.3 0.0 0.052 13.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EPS29374.1 - 0.027 13.3 0.0 0.052 12.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein KaiC PF06745.8 EPS29374.1 - 0.064 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 KaiC DUF258 PF03193.11 EPS29374.1 - 0.064 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 EPS29374.1 - 0.11 12.8 0.0 0.26 11.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter G-alpha PF00503.15 EPS29374.1 - 0.12 11.0 0.2 0.21 10.2 0.1 1.3 1 0 0 1 1 1 0 G-protein alpha subunit Lambda_CIII PF02061.11 EPS29375.1 - 0.14 12.1 0.0 0.57 10.2 0.0 2.0 2 0 0 2 2 2 0 Lambda Phage CIII CFEM PF05730.6 EPS29377.1 - 2.3e-08 33.7 10.4 3e-08 33.3 7.2 1.2 1 0 0 1 1 1 1 CFEM domain WSC PF01822.14 EPS29377.1 - 0.2 11.6 9.1 0.57 10.1 4.7 2.1 1 1 1 2 2 2 0 WSC domain Ribosomal_L16 PF00252.13 EPS29378.1 - 9.3e-33 112.8 0.2 1.2e-32 112.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_L7Ae PF01248.21 EPS29379.1 - 3.9e-26 90.3 0.0 4.5e-26 90.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF342 PF03961.8 EPS29380.1 - 3.5 5.9 9.1 8.7 4.6 6.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4613 PF15390.1 EPS29380.1 - 4.5 5.3 11.3 7 4.7 7.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Laminin_II PF06009.7 EPS29380.1 - 4.5 7.0 13.3 1.5 8.5 6.9 1.9 2 0 0 2 2 2 0 Laminin Domain II Clat_adaptor_s PF01217.15 EPS29381.1 - 3.1e-12 46.3 0.0 1.1e-10 41.4 0.1 2.0 2 0 0 2 2 2 1 Clathrin adaptor complex small chain Homeobox_KN PF05920.6 EPS29381.1 - 0.059 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Homeobox KN domain DUF3441 PF11923.3 EPS29382.1 - 1.9e-37 127.2 0.1 1.9e-37 127.2 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3441) FbpA PF05833.6 EPS29382.1 - 4.4e-33 114.5 21.5 4.4e-33 114.5 14.9 3.0 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 EPS29382.1 - 3.2e-13 49.3 0.0 8.2e-13 48.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Sua5_yciO_yrdC PF01300.13 EPS29383.1 - 4.3e-56 188.9 0.0 6.9e-56 188.3 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 EPS29383.1 - 3.7e-27 94.8 0.0 7.9e-27 93.8 0.0 1.6 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding A_deaminase PF00962.17 EPS29384.1 - 1.2e-71 241.3 0.0 1.3e-71 241.2 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase 2Fe-2S_thioredx PF01257.14 EPS29386.1 - 6.8e-60 200.8 0.1 8.8e-60 200.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin SNF2_N PF00176.18 EPS29387.1 - 3.4e-20 72.0 0.0 4.4e-15 55.2 0.0 2.5 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.12 EPS29387.1 - 8.8e-14 51.3 0.0 2e-13 50.1 0.0 1.5 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase HPD PF05044.7 EPS29387.1 - 0.054 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Homeo-prospero domain zf-RING_5 PF14634.1 EPS29387.1 - 3.7 7.3 22.5 0.13 12.0 3.4 2.8 3 0 0 3 3 3 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EPS29387.1 - 4.1 7.3 11.7 0.06 13.2 0.6 2.7 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EPS29387.1 - 5.8 7.0 19.6 0.13 12.3 2.8 2.9 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) CSTF2_hinge PF14327.1 EPS29388.1 - 1.1e-28 99.0 2.3 1.1e-28 99.0 1.6 2.2 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 EPS29388.1 - 2e-19 68.9 0.0 3e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 EPS29388.1 - 1e-18 66.3 9.7 1e-18 66.3 6.7 2.2 3 0 0 3 3 3 1 Transcription termination and cleavage factor C-terminal RRM_6 PF14259.1 EPS29388.1 - 9.3e-16 57.5 0.0 1.5e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS29388.1 - 1.1e-07 31.5 0.0 1.7e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.1 EPS29388.1 - 0.023 14.1 0.0 0.046 13.2 0.0 1.5 1 0 0 1 1 1 0 Sporulation protein family 7 Band_7 PF01145.20 EPS29389.1 - 2.3e-24 86.2 3.4 3.4e-24 85.7 2.4 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Methyltransf_5 PF01795.14 EPS29389.1 - 0.12 11.6 2.4 0.15 11.2 1.7 1.3 1 1 0 1 1 1 0 MraW methylase family Ank_2 PF12796.2 EPS29390.1 - 1.8e-07 31.3 0.0 1.5e-06 28.4 0.0 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EPS29390.1 - 0.0086 15.8 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.1 EPS29390.1 - 0.14 12.5 0.3 13 6.1 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Nop14 PF04147.7 EPS29390.1 - 1 7.1 8.1 1.2 6.9 5.6 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 EPS29390.1 - 2.1 7.5 7.2 3.5 6.7 5.0 1.3 1 0 0 1 1 1 0 NOA36 protein DUF221 PF02714.10 EPS29391.1 - 2.9e-108 361.5 28.9 2.9e-108 361.5 20.0 1.5 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EPS29391.1 - 3.2e-45 153.4 0.3 3.2e-45 153.4 0.2 3.4 2 1 1 3 3 3 2 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EPS29391.1 - 7.9e-15 54.5 0.0 2.3e-14 53.0 0.0 1.8 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 EPS29391.1 - 4.1e-11 43.2 11.7 1.3e-05 25.5 1.0 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF4463) MCM PF00493.18 EPS29392.1 - 1.5e-139 464.4 0.0 2.2e-139 463.9 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EPS29392.1 - 2.8e-23 82.7 0.0 1.5e-22 80.3 0.0 2.2 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EPS29392.1 - 3.6e-05 23.0 0.0 0.0014 17.7 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EPS29392.1 - 3.7e-05 23.4 0.0 9.6e-05 22.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EPS29392.1 - 0.0045 16.6 0.0 0.013 15.0 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EPS29392.1 - 0.065 12.7 0.1 2.1 7.7 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_32 PF13654.1 EPS29392.1 - 0.31 9.6 2.9 0.14 10.8 0.2 1.6 2 0 0 2 2 2 0 AAA domain VTC PF09359.5 EPS29394.1 - 1.3e-102 342.6 0.1 1.3e-102 342.6 0.1 1.7 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 EPS29394.1 - 8.4e-26 91.3 12.9 3.2e-23 82.8 8.9 3.2 1 1 0 1 1 1 1 SPX domain DUF202 PF02656.10 EPS29394.1 - 3.4e-10 39.9 4.2 3.4e-10 39.9 2.9 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF605 PF04652.11 EPS29395.1 - 9 5.5 13.2 11 5.2 9.1 1.1 1 0 0 1 1 1 0 Vta1 like AIP3 PF03915.8 EPS29396.1 - 0.002 17.0 4.8 0.0026 16.7 3.3 1.1 1 0 0 1 1 1 1 Actin interacting protein 3 Reo_sigmaC PF04582.7 EPS29396.1 - 0.024 13.8 0.4 2.9 6.9 0.0 2.1 1 1 0 2 2 2 0 Reovirus sigma C capsid protein DUF972 PF06156.8 EPS29396.1 - 0.15 12.3 6.0 1.4 9.2 2.6 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Bacillus_HBL PF05791.6 EPS29396.1 - 0.26 10.6 2.8 0.69 9.2 0.6 2.3 2 1 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DUF641 PF04859.7 EPS29396.1 - 0.32 10.7 5.3 0.58 9.9 0.9 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) TBPIP PF07106.8 EPS29396.1 - 0.34 10.4 5.4 1.1 8.8 1.5 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF2968 PF11180.3 EPS29396.1 - 0.69 9.2 3.2 2.8 7.2 0.4 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2968) IncA PF04156.9 EPS29397.1 - 0.0025 17.4 8.9 0.0035 16.9 6.2 1.2 1 0 0 1 1 1 1 IncA protein Cortex-I_coil PF09304.5 EPS29397.1 - 0.0037 17.2 15.1 0.031 14.2 1.9 2.2 1 1 1 2 2 2 2 Cortexillin I, coiled coil Mnd1 PF03962.10 EPS29397.1 - 0.0048 16.5 9.8 0.0056 16.3 6.8 1.1 1 0 0 1 1 1 1 Mnd1 family RmuC PF02646.11 EPS29397.1 - 0.01 14.6 6.7 0.054 12.3 0.7 2.0 2 0 0 2 2 2 0 RmuC family Spc7 PF08317.6 EPS29397.1 - 0.015 13.9 9.6 0.021 13.4 6.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TBCA PF02970.11 EPS29397.1 - 0.02 14.9 13.2 0.16 12.0 3.1 2.3 1 1 1 2 2 2 0 Tubulin binding cofactor A DUF2317 PF10079.4 EPS29397.1 - 0.025 13.2 7.1 0.031 12.8 4.9 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) DUF4404 PF14357.1 EPS29397.1 - 0.026 14.9 9.9 0.031 14.6 1.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) DUF3427 PF11907.3 EPS29397.1 - 0.028 13.4 1.7 0.032 13.1 1.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3427) Filament PF00038.16 EPS29397.1 - 0.029 13.8 12.2 0.11 11.9 8.4 1.7 1 1 0 1 1 1 0 Intermediate filament protein Reo_sigmaC PF04582.7 EPS29397.1 - 0.032 13.3 2.1 3 6.9 0.2 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein AstE_AspA PF04952.9 EPS29397.1 - 0.035 12.9 0.2 0.047 12.5 0.1 1.2 1 1 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family DUF2937 PF11157.3 EPS29397.1 - 0.048 12.9 4.5 1 8.6 0.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2937) NPV_P10 PF05531.7 EPS29397.1 - 0.057 13.6 3.2 2.2 8.6 1.1 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Syntaxin PF00804.20 EPS29397.1 - 0.063 13.4 9.0 1.7 8.8 4.3 2.2 1 1 1 2 2 2 0 Syntaxin Mating_N PF12731.2 EPS29397.1 - 0.074 12.9 0.3 0.27 11.1 0.1 1.8 1 1 1 2 2 2 0 Mating-type protein beta 1 Leu_zip PF15294.1 EPS29397.1 - 0.075 12.1 11.9 0.11 11.5 8.2 1.3 1 0 0 1 1 1 0 Leucine zipper ETF_alpha PF00766.14 EPS29397.1 - 0.079 12.5 0.5 0.31 10.6 0.0 1.9 2 0 0 2 2 2 0 Electron transfer flavoprotein FAD-binding domain Bacillus_HBL PF05791.6 EPS29397.1 - 0.11 11.8 4.1 1.3 8.3 0.1 2.1 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) FliD_C PF07195.7 EPS29397.1 - 0.13 11.5 2.4 3.5 6.8 0.6 2.0 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus SlyX PF04102.7 EPS29397.1 - 0.19 12.1 8.0 1.6 9.1 0.5 2.8 2 1 1 3 3 3 0 SlyX DUF3508 PF12018.3 EPS29397.1 - 0.21 10.5 3.2 0.26 10.2 1.8 1.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3508) Baculo_PEP_C PF04513.7 EPS29397.1 - 0.27 11.0 4.1 11 5.8 2.8 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlgN PF05130.7 EPS29397.1 - 0.3 11.3 10.5 0.55 10.4 7.3 1.5 1 1 0 1 1 1 0 FlgN protein DUF1664 PF07889.7 EPS29397.1 - 0.34 10.7 6.4 0.15 11.8 1.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) COG2 PF06148.6 EPS29397.1 - 0.41 10.5 9.6 0.69 9.7 1.4 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4407 PF14362.1 EPS29397.1 - 0.46 9.3 9.9 0.61 8.9 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cob_adeno_trans PF01923.13 EPS29397.1 - 0.5 10.1 5.1 0.49 10.1 1.0 1.9 1 1 1 2 2 2 0 Cobalamin adenosyltransferase FlaC_arch PF05377.6 EPS29397.1 - 0.51 10.2 5.2 8.1 6.4 0.1 3.1 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.5 EPS29397.1 - 0.55 10.3 4.4 2.5 8.2 2.8 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Spectrin PF00435.16 EPS29397.1 - 0.56 10.5 12.0 0.47 10.7 5.6 2.4 1 1 1 2 2 2 0 Spectrin repeat CCDC-167 PF15188.1 EPS29397.1 - 0.6 10.0 8.2 0.22 11.4 2.8 2.3 1 1 2 3 3 3 0 Coiled-coil domain-containing protein 167 Cytochrom_C_2 PF01322.15 EPS29397.1 - 0.68 10.4 7.6 1.8 9.0 5.3 1.7 1 1 0 1 1 1 0 Cytochrome C' Atg14 PF10186.4 EPS29397.1 - 0.71 8.7 11.6 1.4 7.8 2.3 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 YgaB PF14182.1 EPS29397.1 - 0.76 10.0 7.4 2 8.7 1.6 2.7 1 1 2 3 3 3 0 YgaB-like protein DUF342 PF03961.8 EPS29397.1 - 1.1 7.5 10.1 2.6 6.3 7.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF342) ADIP PF11559.3 EPS29397.1 - 1.1 9.1 9.8 7 6.5 0.4 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.7 EPS29397.1 - 1.1 8.9 16.4 4.8 6.9 11.3 1.9 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein WXG100 PF06013.7 EPS29397.1 - 1.3 9.0 6.2 7.1 6.7 0.2 2.9 1 1 2 4 4 4 0 Proteins of 100 residues with WXG DUF1451 PF07295.6 EPS29397.1 - 1.3 8.7 5.7 1.9 8.2 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) FlxA PF14282.1 EPS29397.1 - 1.7 8.6 7.6 5.5 6.9 5.3 1.9 1 1 0 1 1 1 0 FlxA-like protein ING PF12998.2 EPS29397.1 - 2.8 8.2 6.6 6.5 7.0 4.6 1.7 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding DUF4200 PF13863.1 EPS29397.1 - 3.1 7.7 17.0 5.6 6.9 2.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Dzip-like_N PF13815.1 EPS29397.1 - 3.3 7.5 6.9 4.5 7.1 0.5 2.2 2 0 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal RHH_1 PF01402.16 EPS29397.1 - 3.5 7.6 6.8 4 7.4 0.2 3.3 2 2 1 3 3 3 0 Ribbon-helix-helix protein, copG family Lumazine_bd PF12870.2 EPS29397.1 - 4.5 7.3 7.9 9.5 6.3 3.1 2.0 1 1 1 2 2 2 0 Lumazine-binding domain GrpE PF01025.14 EPS29397.1 - 4.7 6.7 16.0 0.7 9.4 3.6 2.1 1 1 1 2 2 2 0 GrpE HALZ PF02183.13 EPS29397.1 - 6.1 6.6 9.0 15 5.3 0.5 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF972 PF06156.8 EPS29397.1 - 6.8 7.0 10.4 51 4.2 1.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) CDC37_N PF03234.9 EPS29397.1 - 8.6 6.6 10.4 3.4 7.9 1.8 2.0 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding WEMBL PF05701.6 EPS29398.1 - 0.042 12.3 0.5 0.048 12.1 0.3 1.0 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Plasmid_stabil PF05016.9 EPS29398.1 - 0.15 12.5 0.1 0.19 12.1 0.1 1.1 1 0 0 1 1 1 0 Plasmid stabilisation system protein MscS_porin PF12795.2 EPS29399.1 - 0.012 14.9 0.6 0.015 14.6 0.4 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Cortex-I_coil PF09304.5 EPS29399.1 - 0.031 14.3 1.3 0.037 14.0 0.9 1.1 1 0 0 1 1 1 0 Cortexillin I, coiled coil DASH_Spc34 PF08657.5 EPS29400.1 - 0.013 15.2 0.1 0.015 14.9 0.1 1.0 1 0 0 1 1 1 0 DASH complex subunit Spc34 BLOC1_2 PF10046.4 EPS29400.1 - 0.14 12.2 0.7 0.44 10.7 0.5 1.7 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Peptidase_S9 PF00326.16 EPS29403.1 - 9.3e-51 172.0 0.1 1.7e-50 171.2 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EPS29403.1 - 3.7e-09 36.4 0.0 7e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPS29403.1 - 2e-08 34.3 0.1 4.1e-08 33.3 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PD40 PF07676.7 EPS29403.1 - 0.00069 19.2 2.2 0.27 10.9 0.1 3.6 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 EPS29403.1 - 0.0069 15.0 0.0 0.025 13.1 0.0 1.9 2 0 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region COesterase PF00135.23 EPS29403.1 - 0.012 14.3 0.4 0.017 13.8 0.3 1.1 1 0 0 1 1 1 0 Carboxylesterase family DNA_ligase_A_M PF01068.16 EPS29404.1 - 3.2e-57 193.1 0.8 1.4e-54 184.5 0.6 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EPS29404.1 - 2.2e-53 180.6 0.0 3.9e-53 179.8 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EPS29404.1 - 3.5e-28 97.8 0.0 1.5e-27 95.8 0.0 2.2 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region Adeno_E1B_55K_N PF04623.7 EPS29404.1 - 0.028 14.9 0.0 0.028 14.9 0.0 2.3 2 0 0 2 2 2 0 Adenovirus E1B protein N-terminus HEAT_EZ PF13513.1 EPS29405.1 - 0.25 11.8 4.8 0.23 12.0 0.9 3.0 2 0 0 2 2 2 0 HEAT-like repeat DUF4288 PF14119.1 EPS29406.1 - 0.0094 16.0 0.0 0.012 15.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4288) Peptidase_M16_C PF05193.16 EPS29406.1 - 0.046 13.3 0.0 0.071 12.7 0.0 1.4 1 1 0 1 1 1 0 Peptidase M16 inactive domain DpnD-PcfM PF14207.1 EPS29406.1 - 0.11 12.2 0.1 0.19 11.5 0.1 1.3 1 0 0 1 1 1 0 DpnD/PcfM-like protein His_Phos_2 PF00328.17 EPS29407.1 - 1.7e-31 109.8 0.0 2.4e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) EI24 PF07264.6 EPS29409.1 - 7.3e-07 28.8 3.2 1.5e-06 27.8 2.2 1.5 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) DUF3237 PF11578.3 EPS29410.1 - 1.9e-27 95.3 0.0 5.7e-27 93.8 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3237) eIF-5_eIF-2B PF01873.12 EPS29411.1 - 1.3e-39 134.6 0.0 2.6e-39 133.7 0.0 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 EPS29411.1 - 3.5e-25 87.7 0.3 1.2e-24 86.0 0.2 1.9 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Zn-ribbon_8 PF09723.5 EPS29411.1 - 0.4 10.6 2.0 1 9.3 1.4 1.7 1 0 0 1 1 1 0 Zinc ribbon domain Cwf_Cwc_15 PF04889.7 EPS29411.1 - 5.3 6.6 20.0 0.21 11.2 9.5 1.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein HK PF02110.10 EPS29412.1 - 7.9e-75 251.1 0.0 1.8e-74 250.0 0.0 1.6 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 EPS29412.1 - 1.9e-59 199.8 2.7 3.1e-59 199.1 1.9 1.4 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI Carb_kinase PF01256.12 EPS29412.1 - 0.00078 18.8 0.0 0.0019 17.5 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 EPS29412.1 - 0.0087 15.2 0.4 0.072 12.2 0.0 2.6 2 2 1 3 3 3 1 Phosphomethylpyrimidine kinase QRPTase_C PF01729.14 EPS29412.1 - 0.053 13.0 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Isochorismatase PF00857.15 EPS29413.1 - 1.4e-29 103.2 0.1 1.7e-29 102.9 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Lipase_GDSL_2 PF13472.1 EPS29415.1 - 3.4e-28 98.9 0.1 4e-28 98.7 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EPS29415.1 - 9.3e-25 87.8 0.0 1.1e-24 87.5 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Voltage_CLC PF00654.15 EPS29416.1 - 3.8e-94 315.6 21.3 3.8e-94 315.6 14.8 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel PqiA PF04403.8 EPS29416.1 - 0.00059 19.4 2.2 0.0012 18.4 0.6 2.2 2 0 0 2 2 2 1 Paraquat-inducible protein A adh_short PF00106.20 EPS29417.1 - 9.5e-33 113.4 1.1 1.3e-32 113.0 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPS29417.1 - 5.9e-27 94.9 0.1 7.7e-27 94.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPS29417.1 - 3.9e-13 49.4 0.2 5.8e-13 48.8 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPS29417.1 - 0.0003 20.2 0.3 0.0012 18.3 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PA PF02225.17 EPS29417.1 - 0.018 14.7 0.0 0.045 13.4 0.0 1.7 1 0 0 1 1 1 0 PA domain Polysacc_synt_2 PF02719.10 EPS29417.1 - 0.021 13.7 0.0 0.032 13.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DHFR_1 PF00186.14 EPS29418.1 - 1.6e-17 63.5 0.0 1.3e-12 47.5 0.0 2.8 2 1 0 2 2 2 2 Dihydrofolate reductase DUF3184 PF11380.3 EPS29418.1 - 0.078 10.9 2.5 0.1 10.5 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3184) Med22 PF06179.7 EPS29419.1 - 2.5e-22 78.9 1.3 3e-22 78.6 0.9 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex CTK3_C PF12350.3 EPS29419.1 - 0.36 10.8 4.0 0.2 11.7 0.5 2.2 2 1 1 3 3 3 0 CTD kinase subunit gamma CTK3 C-terminus MxiH PF09392.5 EPS29419.1 - 0.51 10.9 2.5 0.95 10.0 1.0 2.1 2 1 0 2 2 2 0 Type III secretion needle MxiH like Cwf_Cwc_15 PF04889.7 EPS29420.1 - 6.5e-87 291.2 17.9 7.3e-87 291.1 12.4 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein APG6 PF04111.7 EPS29420.1 - 1.5 7.7 10.7 2.2 7.2 7.4 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 RR_TM4-6 PF06459.7 EPS29420.1 - 3.9 7.2 11.7 5.6 6.7 8.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tom37_C PF11801.3 EPS29420.1 - 6.8 6.5 7.8 12 5.7 5.4 1.4 1 0 0 1 1 1 0 Tom37 C-terminal domain DUF1510 PF07423.6 EPS29420.1 - 8 5.7 16.6 10 5.3 11.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Sporozoite_P67 PF05642.6 EPS29420.1 - 8.8 4.0 7.8 11 3.6 5.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RNase_PH PF01138.16 EPS29421.1 - 1.6e-18 67.3 0.0 2.6e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EPS29421.1 - 0.00023 21.0 0.0 0.00042 20.2 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 HAD PF12710.2 EPS29422.1 - 7.4e-19 68.6 0.0 1.8e-18 67.4 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EPS29422.1 - 2.5e-16 59.4 0.1 3.9e-16 58.7 0.1 1.2 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EPS29422.1 - 1.1e-14 55.3 0.0 2.9e-14 53.9 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPS29422.1 - 1.4e-12 47.4 0.0 3.5e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EPS29422.1 - 0.0046 16.5 0.1 0.016 14.8 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EPS29422.1 - 0.031 14.5 0.1 0.15 12.2 0.0 2.0 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DNA_pol_lambd_f PF10391.4 EPS29423.1 - 2.7e-20 71.6 0.4 4.8e-20 70.8 0.3 1.4 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_thumb PF14791.1 EPS29423.1 - 9.5e-17 60.4 0.1 4.3e-16 58.3 0.1 2.1 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 EPS29423.1 - 4.4e-16 58.9 0.1 1.1e-15 57.7 0.1 1.6 1 1 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.1 EPS29423.1 - 1.2e-08 35.0 0.1 2.7e-08 33.8 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 EPS29423.1 - 0.011 15.9 0.0 0.026 14.8 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain NicO PF03824.11 EPS29424.1 - 9.8e-55 185.8 23.4 2.3e-54 184.6 4.6 2.5 3 0 0 3 3 3 2 High-affinity nickel-transport protein MIG-14_Wnt-bd PF06664.7 EPS29424.1 - 0.41 9.4 9.1 0.071 11.9 2.8 1.9 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion DUF4231 PF14015.1 EPS29424.1 - 2.4 8.1 10.0 15 5.6 2.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) GMC_oxred_N PF00732.14 EPS29427.1 - 2e-52 178.2 0.0 2.6e-52 177.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EPS29427.1 - 3.3e-32 111.7 0.1 5.5e-32 111.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EPS29427.1 - 3.5e-05 22.8 0.0 0.067 12.0 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EPS29427.1 - 0.00099 18.1 0.0 0.0015 17.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EPS29427.1 - 0.0057 16.6 0.1 0.022 14.7 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EPS29427.1 - 0.021 13.6 0.1 1.6 7.4 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EPS29427.1 - 0.04 13.8 0.1 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EPS29427.1 - 0.056 12.2 0.0 0.2 10.4 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain Pyr_redox_3 PF13738.1 EPS29427.1 - 0.079 13.0 0.0 6.5 6.7 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EPS29427.1 - 0.12 10.8 0.0 1.5 7.1 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Mur_ligase_M PF08245.7 EPS29428.1 - 2.4e-05 24.4 0.0 0.00011 22.2 0.0 1.8 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 EPS29428.1 - 0.0016 18.4 0.0 0.0032 17.4 0.0 1.5 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain HAD_2 PF13419.1 EPS29429.1 - 5.6e-20 72.2 0.0 7e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPS29429.1 - 2.5e-12 47.6 0.2 2.9e-10 40.9 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EPS29429.1 - 3.8e-10 39.3 0.0 8.2e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EPS29429.1 - 1.3e-09 38.5 0.0 1.6e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EPS29429.1 - 3.9e-05 23.4 0.0 0.0062 16.4 0.0 2.4 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EPS29429.1 - 0.032 13.8 0.1 0.6 9.6 0.0 2.3 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Gp-FAR-1 PF05823.7 EPS29429.1 - 0.078 12.9 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Glyco_hydro_71 PF03659.9 EPS29432.1 - 9.2e-157 521.4 7.4 9.2e-157 521.4 5.1 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 71 PAN_1 PF00024.21 EPS29434.1 - 7.4e-06 25.6 0.2 1e-05 25.1 0.2 1.4 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.1 EPS29434.1 - 0.016 14.8 0.4 0.028 14.1 0.3 1.4 1 0 0 1 1 1 0 PAN domain Pkinase PF00069.20 EPS29436.1 - 2.6e-23 82.5 0.0 3.2e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS29436.1 - 2e-19 69.6 0.0 3e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EPS29436.1 - 0.0025 16.9 0.0 0.0039 16.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EPS29436.1 - 0.018 13.9 0.0 0.042 12.8 0.0 1.5 1 1 0 1 1 1 0 Kinase-like RIO1 PF01163.17 EPS29436.1 - 0.029 13.7 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 EPS29436.1 - 0.052 13.2 0.0 0.074 12.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pyridox_oxase_2 PF12766.2 EPS29437.1 - 4.2e-28 97.6 0.0 7.1e-28 96.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Las1 PF04031.8 EPS29438.1 - 3.9e-45 153.2 0.0 6.9e-45 152.4 0.0 1.4 1 0 0 1 1 1 1 Las1-like Lactamase_B PF00753.22 EPS29439.1 - 7.7e-31 107.2 0.2 1e-30 106.8 0.2 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EPS29439.1 - 6.1e-06 25.9 0.0 9.3e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EPS29439.1 - 0.0015 18.2 0.1 0.0033 17.1 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain BcrAD_BadFG PF01869.15 EPS29439.1 - 0.024 13.9 0.0 0.039 13.2 0.0 1.3 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family DUF1275 PF06912.6 EPS29440.1 - 3.9e-47 160.1 9.9 4.7e-47 159.8 6.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF1422 PF07226.6 EPS29440.1 - 0.052 13.2 3.2 0.36 10.5 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1422) WD40 PF00400.27 EPS29442.1 - 1.4e-54 180.1 12.3 3.7e-10 39.2 0.0 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 EPS29442.1 - 2e-13 49.8 0.6 4.1e-13 48.8 0.4 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EPS29442.1 - 2.9e-10 39.5 0.1 7.1e-10 38.2 0.1 1.7 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EPS29442.1 - 5e-10 38.1 8.5 0.012 13.7 0.2 5.2 1 1 4 5 5 5 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EPS29442.1 - 0.15 10.8 0.1 13 4.4 0.1 2.9 1 1 2 3 3 3 0 Nup133 N terminal like Glyco_transf_8 PF01501.15 EPS29443.1 - 0.00036 19.9 0.7 0.0024 17.2 0.0 2.2 1 1 1 2 2 2 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EPS29443.1 - 0.15 11.3 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative Peptidase_M20 PF01546.23 EPS29444.1 - 1.4e-20 73.6 0.1 1.9e-20 73.1 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EPS29444.1 - 7.2e-14 51.4 0.1 2.2e-13 49.9 0.0 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain Glyco_hydro_16 PF00722.16 EPS29445.1 - 6.2e-08 32.1 0.0 1.1e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 TrkH PF02386.11 EPS29446.1 - 1.1e-121 405.6 20.5 2e-119 398.2 6.6 2.1 2 0 0 2 2 2 2 Cation transport protein Fungal_trans PF04082.13 EPS29447.1 - 1.2e-08 34.1 0.0 2.4e-08 33.1 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS29447.1 - 1.4e-07 31.2 10.3 1.4e-07 31.2 7.1 2.1 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RGS PF00615.14 EPS29448.1 - 0.0022 18.1 0.0 0.0044 17.1 0.0 1.5 1 1 0 1 1 1 1 Regulator of G protein signaling domain Lamp PF01299.12 EPS29448.1 - 0.066 12.3 0.2 0.11 11.6 0.1 1.3 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) CAP59_mtransfer PF11735.3 EPS29451.1 - 4.5e-80 268.3 0.0 6.6e-80 267.8 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 IF-2B PF01008.12 EPS29452.1 - 2.6e-70 236.6 0.3 3e-70 236.4 0.2 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family PQQ_3 PF13570.1 EPS29454.1 - 0.00064 19.9 0.4 0.11 12.7 0.0 3.0 2 0 0 2 2 2 1 PQQ-like domain Inositol_P PF00459.20 EPS29454.1 - 0.026 13.8 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 Inositol monophosphatase family SGL PF08450.7 EPS29454.1 - 0.078 12.3 0.1 1.2 8.4 0.0 2.6 1 1 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region Rhomboid PF01694.17 EPS29455.1 - 1.2e-19 70.7 6.9 1.2e-19 70.7 4.8 1.7 2 0 0 2 2 2 1 Rhomboid family CbiM PF01891.11 EPS29455.1 - 0.76 9.3 8.6 0.27 10.8 3.0 2.2 2 1 1 3 3 3 0 Cobalt uptake substrate-specific transmembrane region Metallophos PF00149.23 EPS29456.1 - 2.1e-09 37.1 0.9 4.5e-09 35.9 0.6 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Med19 PF10278.4 EPS29456.1 - 2.6 7.6 11.8 2 8.0 0.9 2.3 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 CENP-X PF09415.5 EPS29457.1 - 0.061 13.1 0.2 1.1 9.1 0.1 2.6 2 0 0 2 2 2 0 CENP-S associating Centromere protein X FAD_binding_3 PF01494.14 EPS29458.1 - 3.7e-81 272.9 0.0 3.8e-79 266.3 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EPS29458.1 - 1.1e-32 113.0 0.0 1.7e-32 112.3 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Thi4 PF01946.12 EPS29458.1 - 8.4e-05 21.7 0.0 0.00014 21.0 0.0 1.2 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EPS29458.1 - 0.00012 20.6 0.1 0.00022 19.8 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EPS29458.1 - 0.00017 20.5 0.2 0.00025 20.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EPS29458.1 - 0.00078 18.4 0.1 0.002 17.0 0.0 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPS29458.1 - 0.0028 17.6 0.1 0.008 16.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EPS29458.1 - 0.0033 16.5 0.3 0.005 15.9 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EPS29458.1 - 0.004 17.0 0.6 0.014 15.3 0.2 2.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EPS29458.1 - 0.0085 14.9 0.1 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 EPS29458.1 - 0.098 13.0 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Zn_clus PF00172.13 EPS29459.1 - 9.6e-11 41.4 10.2 1.7e-10 40.6 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EPS29459.1 - 1.2e-09 37.4 0.4 3.2e-09 36.0 0.3 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_transf_90 PF05686.7 EPS29460.1 - 1.8e-34 119.1 0.0 2.6e-34 118.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.1 EPS29460.1 - 0.00056 20.1 0.0 0.0012 19.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Amidohydro_1 PF01979.15 EPS29461.1 - 1.9e-35 123.1 0.0 2.4e-35 122.7 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EPS29461.1 - 9.6e-06 25.0 0.2 0.0018 17.5 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EPS29461.1 - 0.0062 16.6 0.8 4.5 7.2 0.0 2.7 3 0 0 3 3 3 2 Amidohydrolase Amidohydro_5 PF13594.1 EPS29461.1 - 0.0079 15.9 0.0 0.021 14.6 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 EPS29461.1 - 0.014 14.3 0.0 0.025 13.5 0.0 1.3 1 0 0 1 1 1 0 Adenosine/AMP deaminase Toxin_29 PF08116.6 EPS29461.1 - 0.066 12.9 0.5 0.12 12.1 0.4 1.4 1 0 0 1 1 1 0 PhTx neurotoxin family Fungal_trans PF04082.13 EPS29462.1 - 1.9e-20 72.8 0.0 3.7e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS29462.1 - 5.3e-07 29.4 8.9 9.5e-07 28.6 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.16 EPS29464.1 - 4.7e-73 246.5 0.1 6.1e-73 246.1 0.1 1.1 1 0 0 1 1 1 1 Amidase Isochorismatase PF00857.15 EPS29464.1 - 3e-42 144.5 0.1 6.9e-42 143.3 0.0 1.6 2 0 0 2 2 2 1 Isochorismatase family Transp_cyt_pur PF02133.10 EPS29465.1 - 6.5e-96 321.5 41.7 8.1e-96 321.2 28.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin ACC_central PF08326.7 EPS29466.1 - 9.8e-262 870.1 0.0 1.4e-261 869.7 0.0 1.2 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 EPS29466.1 - 1.1e-181 604.5 0.0 1.6e-181 603.9 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 EPS29466.1 - 2.4e-51 174.0 0.0 4.5e-51 173.1 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EPS29466.1 - 7.5e-24 83.9 0.1 1.4e-23 83.0 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EPS29466.1 - 9.9e-23 80.1 0.0 1.2e-19 70.2 0.0 3.7 4 0 0 4 4 4 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EPS29466.1 - 4.7e-17 61.3 0.1 1.3e-16 60.0 0.0 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EPS29466.1 - 1.6e-09 37.7 0.0 3.7e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EPS29466.1 - 3.6e-08 32.5 0.0 0.017 13.8 0.0 3.2 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EPS29466.1 - 0.0002 20.7 0.0 0.00044 19.7 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EPS29466.1 - 0.002 18.0 0.0 0.0067 16.3 0.0 1.9 1 0 0 1 1 1 1 ATP-grasp domain NUDE_C PF04880.8 EPS29469.1 - 4.2e-31 108.5 2.4 4.2e-31 108.5 1.7 4.7 2 1 0 4 4 2 1 NUDE protein, C-terminal conserved region DUF904 PF06005.7 EPS29469.1 - 7.8e-05 22.8 5.6 7.8e-05 22.8 3.9 4.0 2 1 2 4 4 4 1 Protein of unknown function (DUF904) WEMBL PF05701.6 EPS29469.1 - 0.012 14.0 21.2 0.017 13.6 14.7 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Ax_dynein_light PF10211.4 EPS29469.1 - 0.013 15.3 12.4 0.013 15.3 8.6 2.3 2 0 0 2 2 2 0 Axonemal dynein light chain BAR_2 PF10455.4 EPS29469.1 - 0.014 14.3 8.3 0.024 13.5 5.7 1.3 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking ATG16 PF08614.6 EPS29469.1 - 0.053 13.3 27.3 0.51 10.1 8.5 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) AsmA PF05170.9 EPS29469.1 - 0.095 11.2 2.5 0.14 10.7 1.7 1.1 1 0 0 1 1 1 0 AsmA family MAD PF05557.8 EPS29469.1 - 0.65 8.0 24.2 1.6 6.6 16.8 1.6 1 1 0 1 1 1 0 Mitotic checkpoint protein RTBV_P46 PF06216.6 EPS29469.1 - 1.4 7.7 13.0 1.9 7.2 0.3 2.2 1 1 1 2 2 2 0 Rice tungro bacilliform virus P46 protein IncA PF04156.9 EPS29469.1 - 1.8 8.1 29.7 0.83 9.2 10.5 2.7 2 1 1 3 3 3 0 IncA protein GrpE PF01025.14 EPS29469.1 - 1.9 8.0 19.7 0.44 10.0 10.4 2.2 1 1 1 2 2 2 0 GrpE DUF4407 PF14362.1 EPS29469.1 - 3.1 6.6 8.0 5 5.9 5.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ADIP PF11559.3 EPS29469.1 - 3.7 7.4 27.9 1.6 8.6 1.2 3.3 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding FliD_N PF02465.13 EPS29469.1 - 5 7.5 8.7 21 5.5 0.1 2.9 1 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Tropomyosin_1 PF12718.2 EPS29469.1 - 5.4 6.8 31.7 3.1 7.6 16.2 3.1 2 1 1 3 3 3 0 Tropomyosin like DUF1664 PF07889.7 EPS29469.1 - 6.8 6.5 10.6 1.3 8.8 4.1 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Isochorismatase PF00857.15 EPS29470.1 - 3.8e-42 144.1 0.0 9.4e-42 142.8 0.0 1.6 2 0 0 2 2 2 1 Isochorismatase family FAR1 PF03101.10 EPS29470.1 - 1.8e-06 28.3 0.0 3.6e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain AFT PF08731.6 EPS29470.1 - 0.021 15.0 0.0 0.039 14.1 0.0 1.4 1 0 0 1 1 1 0 Transcription factor AFT PriCT_2 PF08707.6 EPS29470.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Primase C terminal 2 (PriCT-2) Sedlin_N PF04628.8 EPS29471.1 - 1.8e-41 141.0 0.0 2.1e-41 140.8 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EPS29471.1 - 0.00035 20.2 0.0 0.0025 17.4 0.0 1.9 2 0 0 2 2 2 1 Sybindin-like family DUF2040 PF09745.4 EPS29472.1 - 1.4e-41 141.2 17.1 1.4e-41 141.2 11.8 4.5 4 1 0 4 4 4 1 Coiled-coil domain-containing protein 55 (DUF2040) Phage_int_SAM_2 PF12834.2 EPS29472.1 - 0.013 15.8 1.4 0.058 13.7 0.6 2.3 2 0 0 2 2 2 0 Phage integrase, N-terminal BON PF04972.12 EPS29472.1 - 0.038 13.7 1.0 0.15 11.8 0.7 2.0 1 0 0 1 1 1 0 BON domain Ribosomal_S30 PF04758.9 EPS29473.1 - 2.1e-28 97.8 4.8 2.5e-28 97.6 3.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 TPR_12 PF13424.1 EPS29475.1 - 2.1e-09 37.1 10.7 1.1 9.2 0.1 8.9 8 0 0 8 8 8 3 Tetratricopeptide repeat AAA_16 PF13191.1 EPS29475.1 - 2.2e-09 37.5 1.2 1e-07 32.1 0.0 3.4 3 0 0 3 3 3 1 AAA ATPase domain NACHT PF05729.7 EPS29475.1 - 6.6e-07 29.1 0.0 2.7e-06 27.1 0.0 2.1 1 0 0 1 1 1 1 NACHT domain TPR_7 PF13176.1 EPS29475.1 - 7.4e-06 25.3 11.8 1.8 8.5 0.0 7.7 7 0 0 7 7 7 1 Tetratricopeptide repeat AAA_22 PF13401.1 EPS29475.1 - 3.2e-05 24.0 0.0 0.0002 21.5 0.0 2.5 1 0 0 1 1 1 1 AAA domain TPR_14 PF13428.1 EPS29475.1 - 4.1e-05 23.8 1.7 14 6.6 0.1 6.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 EPS29475.1 - 0.011 16.0 5.4 0.11 12.9 0.1 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 EPS29475.1 - 4.5 7.3 11.6 5.4 7.0 0.0 6.2 8 0 0 8 8 8 0 Tetratricopeptide repeat SIMPL PF04402.9 EPS29476.1 - 1.3e-27 97.1 1.2 4.5e-27 95.2 0.8 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF541) Zip PF02535.17 EPS29477.1 - 1.5e-29 103.0 12.0 6.6e-29 100.9 8.3 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter Endonuclease_NS PF01223.18 EPS29478.1 - 2.3e-61 207.0 0.0 3.1e-61 206.6 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease zf-C3HC4_2 PF13923.1 EPS29479.1 - 7.6e-08 32.2 13.5 0.00011 22.1 2.2 3.0 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPS29479.1 - 6.2e-06 25.9 11.2 0.0017 18.1 3.4 2.6 2 1 0 2 2 2 2 Ring finger domain zf-C3HC4 PF00097.20 EPS29479.1 - 0.00037 20.0 2.4 0.00037 20.0 1.7 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPS29479.1 - 0.00043 19.9 13.3 0.00088 18.9 4.5 2.8 2 1 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EPS29479.1 - 0.0042 16.7 3.5 0.0042 16.7 2.4 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 EPS29479.1 - 0.01 15.5 16.1 0.071 12.7 5.5 3.4 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 EPS29479.1 - 0.014 15.2 11.7 0.076 12.9 2.9 3.2 1 1 1 2 2 2 0 FYVE zinc finger Atg14 PF10186.4 EPS29479.1 - 0.089 11.7 9.0 0.16 10.8 6.2 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF1844 PF08899.6 EPS29479.1 - 0.72 9.8 2.8 1.4 8.8 1.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1844) zf-C3HC4_4 PF15227.1 EPS29479.1 - 4.3 7.2 12.8 0.3 11.0 1.4 3.1 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING Sec7 PF01369.15 EPS29480.1 - 3e-41 141.1 0.0 5.9e-41 140.2 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EPS29480.1 - 6.2e-07 29.5 0.1 1.2e-06 28.6 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EPS29480.1 - 2.5e-05 24.3 0.1 5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 PH domain Peptidase_M14 PF00246.19 EPS29481.1 - 2.1e-75 253.9 0.0 2.6e-75 253.6 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase AA_permease PF00324.16 EPS29482.1 - 3.7e-124 414.6 33.6 4.6e-124 414.3 23.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPS29482.1 - 1.8e-34 119.0 38.8 2.3e-34 118.7 26.9 1.1 1 0 0 1 1 1 1 Amino acid permease AMP-binding PF00501.23 EPS29486.1 - 1.1e-26 93.1 0.0 1.6e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EPS29486.1 - 1.2e-22 80.1 0.0 2.5e-15 56.1 0.0 2.3 1 1 1 2 2 2 2 Male sterility protein PP-binding PF00550.20 EPS29486.1 - 1.8e-09 37.6 0.3 3.5e-09 36.7 0.2 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EPS29486.1 - 0.012 15.1 0.0 1.2 8.5 0.0 3.0 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EPS29486.1 - 0.16 12.2 0.0 0.57 10.4 0.0 2.0 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 EPS29488.1 - 7.7e-35 120.0 0.0 1.6e-34 118.9 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.23 EPS29488.1 - 7.4e-23 80.6 0.0 7.3e-17 60.8 0.0 3.3 3 0 0 3 3 3 3 AMP-binding enzyme Epimerase PF01370.16 EPS29488.1 - 7.6e-10 38.6 0.0 1.1e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EPS29488.1 - 6.2e-05 23.1 0.0 0.00018 21.7 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 EPS29488.1 - 0.016 15.1 0.0 0.077 12.9 0.0 2.1 1 1 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.14 EPS29488.1 - 0.059 12.0 0.0 1.1 7.9 0.0 2.4 2 1 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF4329 PF14220.1 EPS29488.1 - 0.061 13.2 0.2 0.4 10.6 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4329) FSH1 PF03959.8 EPS29489.1 - 7.7e-26 90.8 0.0 4.3e-25 88.3 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EPS29489.1 - 0.00036 20.4 0.0 0.00064 19.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.6 EPS29489.1 - 0.058 12.8 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain ADH_zinc_N PF00107.21 EPS29490.1 - 2.2e-11 43.4 0.1 6.3e-11 41.9 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPS29490.1 - 1.2e-06 28.2 2.4 2.5e-06 27.1 1.1 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ketoacyl-synt PF00109.21 EPS29491.1 - 3.9e-75 252.6 0.1 9.9e-75 251.2 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EPS29491.1 - 5.1e-56 190.3 0.1 9.7e-56 189.4 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EPS29491.1 - 2.6e-53 180.3 0.1 6.9e-53 179.0 0.0 1.8 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 EPS29491.1 - 4.6e-50 170.4 1.0 1.4e-49 168.8 0.0 2.1 2 0 0 2 2 2 1 Polyketide synthase dehydratase adh_short PF00106.20 EPS29491.1 - 5e-42 143.6 0.2 1.6e-41 141.9 0.1 2.0 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EPS29491.1 - 2.3e-33 114.5 0.1 8.1e-33 112.8 0.1 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EPS29491.1 - 1.7e-06 28.1 0.7 5.4e-06 26.5 0.1 2.2 2 0 0 2 2 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EPS29491.1 - 8.6e-05 22.0 0.0 0.00016 21.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Thiolase_N PF00108.18 EPS29491.1 - 0.0049 15.8 0.0 0.01 14.8 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 EPS29491.1 - 0.0049 16.4 0.1 0.087 12.5 0.1 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III adh_short_C2 PF13561.1 EPS29491.1 - 0.029 14.1 0.0 0.06 13.1 0.0 1.5 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase mRNA_stabil PF13929.1 EPS29491.1 - 0.055 12.4 0.0 0.12 11.2 0.0 1.5 1 0 0 1 1 1 0 mRNA stabilisation Abhydrolase_3 PF07859.8 EPS29492.1 - 3.8e-12 46.2 0.6 8.4e-09 35.3 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPS29492.1 - 2e-11 43.8 0.1 3e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EPS29492.1 - 6.2e-11 41.9 0.1 5.8e-05 22.3 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EPS29492.1 - 7.8e-07 29.2 0.1 1e-06 28.8 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EPS29492.1 - 1.3e-06 27.5 0.0 1.8e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_2 PF02230.11 EPS29492.1 - 1.8e-05 24.2 1.5 0.18 11.2 0.0 3.0 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Chlorophyllase PF07224.6 EPS29492.1 - 5.8e-05 22.0 0.0 8.3e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Peptidase_S15 PF02129.13 EPS29492.1 - 0.0011 18.4 0.0 0.4 10.0 0.0 2.6 3 0 0 3 3 3 2 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 EPS29492.1 - 0.0021 16.6 0.0 0.21 10.0 0.0 2.3 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) DLH PF01738.13 EPS29492.1 - 0.0094 15.2 0.0 0.27 10.5 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family DUF2920 PF11144.3 EPS29492.1 - 0.062 12.3 0.0 0.09 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2920) DUF829 PF05705.9 EPS29492.1 - 0.16 11.6 0.0 0.39 10.3 0.0 1.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF829) F-box-like PF12937.2 EPS29494.1 - 0.0059 16.2 0.0 0.016 14.9 0.0 1.8 1 0 0 1 1 1 1 F-box-like PP-binding PF00550.20 EPS29496.1 - 3e-06 27.4 0.1 4.4e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site E1-E2_ATPase PF00122.15 EPS29497.1 - 7.4e-52 175.6 1.3 1.4e-51 174.7 0.9 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EPS29497.1 - 6.8e-38 130.0 3.1 6.8e-38 130.0 2.2 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EPS29497.1 - 8.2e-29 101.5 0.0 2.9e-23 83.4 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPS29497.1 - 1.4e-16 60.2 0.0 2.6e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EPS29497.1 - 7.7e-15 55.5 0.0 2.2e-14 54.0 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EPS29497.1 - 2.7e-14 52.3 0.0 5.8e-14 51.3 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EPS29497.1 - 5.4e-05 22.8 0.1 0.00012 21.7 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Bac_rhodopsin PF01036.13 EPS29498.1 - 2e-60 203.8 19.0 2.3e-60 203.6 13.1 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Antitoxin-MazE PF04014.13 EPS29498.1 - 0.018 14.7 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Antidote-toxin recognition MazE RPE65 PF03055.10 EPS29500.1 - 6.4e-120 400.9 0.0 7.3e-120 400.7 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein dCMP_cyt_deam_1 PF00383.17 EPS29501.1 - 1.6e-06 27.6 0.0 2e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 EPS29501.1 - 0.021 14.2 1.1 0.9 8.8 0.7 2.4 1 1 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases YwqJ-deaminase PF14431.1 EPS29501.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 YwqJ-like deaminase Aldo_ket_red PF00248.16 EPS29502.1 - 3.5e-71 239.3 0.0 4e-71 239.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Oxidored_molyb PF00174.14 EPS29503.1 - 9.7e-53 178.0 0.0 1.4e-52 177.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EPS29503.1 - 1.4e-28 99.1 0.3 3.6e-28 97.7 0.2 1.7 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.23 EPS29503.1 - 8.1e-13 47.9 0.0 1.5e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Alpha-amylase PF00128.19 EPS29504.1 - 3.4e-101 338.7 2.6 5.8e-101 338.0 1.8 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 EPS29504.1 - 0.00024 21.1 0.2 0.0013 18.8 0.0 2.5 2 1 1 3 3 3 1 Alpha amylase, C-terminal all-beta domain DUF3459 PF11941.3 EPS29504.1 - 0.07 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) Fungal_trans PF04082.13 EPS29505.1 - 1.7e-10 40.1 0.0 2.7e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EPS29506.1 - 9.2e-23 80.5 22.3 1.3e-22 80.0 15.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TauD PF02668.11 EPS29507.1 - 4.5e-49 167.4 0.0 5.7e-49 167.0 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Terpene_synth_C PF03936.11 EPS29508.1 - 0.0011 18.3 0.7 0.0022 17.2 0.5 1.5 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain Glyco_hydro_28 PF00295.12 EPS29509.1 - 2.8e-88 296.0 11.8 2.8e-88 296.0 8.2 2.1 3 0 0 3 3 3 1 Glycosyl hydrolases family 28 Pectinesterase PF01095.14 EPS29509.1 - 1.5e-43 148.4 0.8 3.4e-43 147.3 0.3 1.7 2 0 0 2 2 2 1 Pectinesterase Beta_helix PF13229.1 EPS29509.1 - 6.9e-06 25.9 18.3 6.9e-06 25.9 12.7 4.4 4 1 0 4 4 4 1 Right handed beta helix region H_lectin PF09458.5 EPS29509.1 - 0.088 12.4 0.7 0.43 10.2 0.5 2.3 1 0 0 1 1 1 0 H-type lectin domain Sulfatase PF00884.18 EPS29510.1 - 6.4e-65 219.3 0.5 9.2e-65 218.8 0.3 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EPS29510.1 - 0.00054 19.3 3.4 0.0065 15.8 2.4 2.0 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Antimicrobial18 PF08130.6 EPS29510.1 - 0.072 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Type A lantibiotic family Fungal_trans PF04082.13 EPS29511.1 - 2.2e-20 72.6 0.1 1.3e-19 70.1 0.1 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS29511.1 - 2.8e-09 36.7 10.8 5.4e-09 35.8 7.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4306 PF14154.1 EPS29511.1 - 0.23 11.4 0.7 0.47 10.4 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4306) FAD_binding_7 PF03441.9 EPS29512.1 - 2.1e-94 315.8 0.5 3.2e-94 315.2 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EPS29512.1 - 2.2e-39 134.8 0.1 4.5e-39 133.8 0.1 1.5 1 0 0 1 1 1 1 DNA photolyase Aminotran_4 PF01063.14 EPS29515.1 - 1e-20 74.2 0.0 1.3e-20 73.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV 3-alpha PF03475.9 EPS29516.1 - 0.099 12.3 0.2 0.099 12.3 0.1 2.2 2 0 0 2 2 2 0 3-alpha domain Pkinase PF00069.20 EPS29517.1 - 2e-42 145.1 0.0 3.3e-42 144.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 EPS29517.1 - 8.1e-41 138.8 0.0 1.7e-40 137.8 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 EPS29517.1 - 3.8e-21 75.3 0.0 9.4e-21 74.0 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase PQQ_2 PF13360.1 EPS29517.1 - 0.00086 18.8 0.1 0.016 14.6 0.0 2.2 2 0 0 2 2 2 1 PQQ-like domain PQQ PF01011.16 EPS29517.1 - 0.0033 16.8 0.1 0.52 9.9 0.0 2.8 2 0 0 2 2 2 1 PQQ enzyme repeat YrbL-PhoP_reg PF10707.4 EPS29517.1 - 0.015 14.6 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 EPS29517.1 - 0.025 13.6 0.0 0.048 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_76 PF03663.9 EPS29518.1 - 1.5e-134 449.0 20.4 2e-134 448.6 14.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Cloacin_immun PF03513.9 EPS29518.1 - 0.00049 20.0 0.1 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Cloacin immunity protein Cpn60_TCP1 PF00118.19 EPS29519.1 - 1e-134 449.7 8.7 1.2e-134 449.5 6.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PAD_M PF08527.5 EPS29519.1 - 0.088 12.2 0.0 0.81 9.0 0.0 2.1 2 0 0 2 2 2 0 Protein-arginine deiminase (PAD) middle domain Pro_isomerase PF00160.16 EPS29520.1 - 5e-51 172.9 0.1 1e-50 171.9 0.1 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EPS29520.1 - 2.6e-16 58.8 2.2 7.9e-07 28.7 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat Cir_Bir_Yir PF06022.6 EPS29521.1 - 0.083 12.1 0.1 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir Glycophorin_A PF01102.13 EPS29521.1 - 0.1 12.3 1.3 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 Glycophorin A TMEM154 PF15102.1 EPS29521.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family DUF4381 PF14316.1 EPS29521.1 - 0.18 11.9 2.8 0.28 11.2 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Sporozoite_P67 PF05642.6 EPS29522.1 - 0.28 8.9 2.9 0.32 8.8 2.0 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MFS_1 PF07690.11 EPS29523.1 - 3.1e-39 134.6 21.0 3.1e-39 134.6 14.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS29523.1 - 1.5e-08 33.7 2.7 1.5e-08 33.7 1.9 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EPS29523.1 - 0.0019 16.5 2.8 0.0031 15.7 2.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1129 PF06570.6 EPS29523.1 - 0.093 12.0 3.3 3.8 6.7 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) DUF515 PF04415.7 EPS29524.1 - 0.11 10.6 3.4 0.16 10.1 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) COX5A PF02284.11 EPS29524.1 - 0.14 12.1 0.0 21 5.1 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Va MFS_1 PF07690.11 EPS29526.1 - 2e-33 115.5 30.2 2.8e-33 115.1 20.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_11 PF00457.12 EPS29528.1 - 6.8e-68 227.6 18.2 7.9e-68 227.4 12.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Maff2 PF12750.2 EPS29528.1 - 0.12 11.8 0.0 0.3 10.6 0.0 1.6 1 0 0 1 1 1 0 Maff2 family SKG6 PF08693.5 EPS29529.1 - 1.7e-08 33.6 0.1 3.7e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mid2 PF04478.7 EPS29529.1 - 0.0069 15.8 0.2 0.022 14.1 0.0 1.7 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor Fil_haemagg_2 PF13332.1 EPS29529.1 - 0.0088 15.8 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 Haemagluttinin repeat Gly-zipper_OmpA PF13436.1 EPS29529.1 - 0.055 13.1 0.5 0.086 12.4 0.4 1.2 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain DUF3611 PF12263.3 EPS29529.1 - 0.067 12.5 0.1 0.12 11.7 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) TrbC PF04956.8 EPS29529.1 - 0.13 12.2 1.8 0.15 12.0 0.5 1.6 2 0 0 2 2 2 0 TrbC/VIRB2 family Pcc1 PF09341.5 EPS29530.1 - 0.087 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Transcription factor Pcc1 Fungal_trans_2 PF11951.3 EPS29531.1 - 5.5e-49 166.7 1.1 8.4e-49 166.1 0.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS29531.1 - 5.7e-10 38.9 8.6 1.3e-09 37.7 6.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Far-17a_AIG1 PF04750.9 EPS29532.1 - 1e-77 259.8 10.0 1.2e-77 259.6 6.9 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Pam17 PF08566.5 EPS29533.1 - 4.6e-70 234.8 0.0 5.9e-70 234.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 ECH PF00378.15 EPS29534.1 - 9.9e-35 119.8 0.0 1.3e-34 119.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family adh_short PF00106.20 EPS29537.1 - 4.9e-13 49.3 0.7 8e-13 48.6 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPS29537.1 - 8.1e-08 32.1 0.6 1.2e-07 31.5 0.4 1.2 1 0 0 1 1 1 1 KR domain BNR_2 PF13088.1 EPS29538.1 - 2.2e-11 43.5 0.8 5.7e-09 35.6 0.3 2.9 1 1 0 2 2 2 2 BNR repeat-like domain BNR PF02012.15 EPS29538.1 - 1.1e-07 30.5 15.9 0.092 12.6 0.4 5.3 6 0 0 6 6 6 4 BNR/Asp-box repeat Mo-co_dimer PF03404.11 EPS29538.1 - 0.13 11.8 0.1 14 5.2 0.0 2.7 3 0 0 3 3 3 0 Mo-co oxidoreductase dimerisation domain MFS_1 PF07690.11 EPS29539.1 - 3.2e-25 88.5 35.4 1.4e-24 86.4 22.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EPS29539.1 - 0.00024 19.4 4.7 0.00037 18.8 3.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) G_glu_transpept PF01019.16 EPS29540.1 - 3.8e-145 484.2 0.1 4.4e-145 484.0 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase FAA_hydrolase PF01557.13 EPS29541.1 - 2.6e-49 167.6 0.0 3.2e-49 167.3 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family YlqD PF11068.3 EPS29541.1 - 0.079 12.9 0.1 0.11 12.4 0.1 1.5 1 1 0 1 1 1 0 YlqD protein DHquinase_I PF01487.10 EPS29542.1 - 6.8e-42 143.6 0.0 9.7e-42 143.1 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 EPS29542.1 - 4.4e-18 65.6 0.3 4.8e-17 62.2 0.0 2.6 3 0 0 3 3 3 1 Shikimate kinase Shikimate_DH PF01488.15 EPS29542.1 - 6.2e-14 52.2 0.1 2.1e-13 50.5 0.1 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Shikimate_dh_N PF08501.6 EPS29542.1 - 2.3e-12 46.7 0.0 4.9e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain F420_oxidored PF03807.12 EPS29542.1 - 0.014 15.8 0.0 0.034 14.5 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.16 EPS29542.1 - 0.16 11.7 0.0 0.55 10.0 0.0 1.9 2 0 0 2 2 2 0 ThiF family SLS PF14611.1 EPS29543.1 - 6e-46 156.5 0.1 1.1e-45 155.6 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator DUF2007 PF09413.5 EPS29543.1 - 0.076 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2007) Ribosomal_L9_N PF01281.14 EPS29543.1 - 0.081 12.1 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L9, N-terminal domain DUF202 PF02656.10 EPS29544.1 - 1.7e-16 60.2 3.1 1.7e-16 60.2 2.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Fumarate_red_C PF02300.12 EPS29544.1 - 0.053 13.4 1.1 0.079 12.8 0.7 1.3 1 0 0 1 1 1 0 Fumarate reductase subunit C DUF2937 PF11157.3 EPS29544.1 - 1.3 8.3 4.5 0.34 10.2 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) adh_short PF00106.20 EPS29545.1 - 1.2e-34 119.6 0.5 1.6e-34 119.2 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPS29545.1 - 2.9e-30 105.7 0.0 3.9e-30 105.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPS29545.1 - 2.4e-19 69.6 0.2 3.6e-19 69.1 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPS29545.1 - 3.6e-06 26.5 0.2 4.8e-06 26.1 0.2 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EPS29545.1 - 0.0039 16.2 0.1 0.22 10.5 0.0 2.2 1 1 1 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 EPS29545.1 - 0.0089 15.7 0.3 0.02 14.6 0.2 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Methyltransf_18 PF12847.2 EPS29545.1 - 0.04 14.5 0.0 0.11 13.0 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain NAD_binding_10 PF13460.1 EPS29545.1 - 0.045 13.7 0.5 0.088 12.8 0.3 1.5 1 1 0 1 1 1 0 NADH(P)-binding Scytalone_dh PF02982.9 EPS29546.1 - 4.6e-79 263.5 2.7 5.7e-79 263.2 1.9 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 EPS29546.1 - 6.7e-09 35.7 2.2 7.8e-09 35.5 1.5 1.1 1 0 0 1 1 1 1 SnoaL-like domain Abhydrolase_3 PF07859.8 EPS29547.1 - 8.1e-71 237.9 0.1 5.1e-70 235.3 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.23 EPS29547.1 - 3.9e-11 42.3 1.3 8.9e-11 41.1 0.9 1.5 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 EPS29547.1 - 5.3e-11 42.1 0.0 8.6e-11 41.4 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EPS29547.1 - 0.0003 20.5 0.0 0.003 17.3 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF2424 PF10340.4 EPS29547.1 - 0.00051 18.7 0.0 0.0025 16.5 0.0 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2424) Chlorophyllase2 PF12740.2 EPS29547.1 - 0.13 11.1 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme adh_short PF00106.20 EPS29548.1 - 3.3e-26 92.1 0.9 4e-26 91.8 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPS29548.1 - 2.3e-19 70.1 0.0 2.8e-19 69.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPS29548.1 - 5.8e-10 39.1 0.4 9.6e-10 38.4 0.3 1.3 1 0 0 1 1 1 1 KR domain MR_MLE_C PF13378.1 EPS29549.1 - 2.7e-20 72.4 0.0 4.8e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EPS29549.1 - 1.8e-12 47.6 0.0 3.4e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EPS29549.1 - 1.2e-09 38.1 0.0 2e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain DUF4149 PF13664.1 EPS29550.1 - 4.4e-21 74.8 2.7 7.4e-21 74.1 0.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) bZIP_1 PF00170.16 EPS29551.1 - 0.0009 19.1 6.8 0.0017 18.3 4.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor adh_short PF00106.20 EPS29552.1 - 1.1e-16 61.2 3.0 1.4e-14 54.3 2.1 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPS29552.1 - 1.3e-08 34.7 0.2 6.2e-08 32.5 0.0 2.0 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 EPS29552.1 - 0.0011 17.9 0.0 0.0018 17.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EPS29552.1 - 0.0016 18.5 0.0 0.0036 17.3 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EPS29552.1 - 0.06 13.3 0.3 0.14 12.1 0.2 1.9 1 1 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 EPS29552.1 - 0.076 12.4 0.1 0.34 10.3 0.1 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Fungal_trans PF04082.13 EPS29553.1 - 8.9e-35 119.8 0.0 2.9e-33 114.8 0.0 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS29553.1 - 5.7e-08 32.5 8.7 1e-07 31.7 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_60s PF00428.14 EPS29553.1 - 0.00074 19.8 0.5 0.002 18.4 0.4 1.7 1 0 0 1 1 1 1 60s Acidic ribosomal protein Hydrolase_6 PF13344.1 EPS29554.1 - 1.1e-30 105.4 0.0 2.3e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPS29554.1 - 4e-14 53.5 0.0 5.8e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EPS29554.1 - 3.1e-11 42.8 0.0 2.5e-10 39.9 0.0 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 EPS29554.1 - 2.1e-06 28.1 0.1 0.00018 21.7 0.1 2.7 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 EPS29554.1 - 0.02 14.2 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Hydrolase_3 PF08282.7 EPS29554.1 - 0.067 12.7 0.0 0.091 12.3 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase CaMKII_AD PF08332.5 EPS29554.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Calcium/calmodulin dependent protein kinase II Association CW_binding_2 PF04122.7 EPS29554.1 - 0.16 12.2 0.2 4.9 7.4 0.0 2.9 2 1 0 2 2 2 0 Putative cell wall binding repeat 2 Tyrosinase PF00264.15 EPS29555.1 - 2.7e-45 155.2 0.0 3.6e-45 154.8 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Lactonase PF10282.4 EPS29556.1 - 3e-87 292.9 0.1 3.6e-87 292.6 0.1 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller DUF814 PF05670.8 EPS29557.1 - 5.3e-18 64.6 0.1 1.4e-17 63.3 0.0 1.8 3 0 0 3 3 3 1 Domain of unknown function (DUF814) TBCC PF07986.7 EPS29557.1 - 0.041 13.2 0.0 0.19 11.1 0.0 2.0 2 1 0 2 2 2 0 Tubulin binding cofactor C DUF3340 PF11818.3 EPS29557.1 - 0.13 12.2 10.7 0.085 12.8 6.3 1.4 2 0 0 2 2 2 0 C-terminal domain of tail specific protease (DUF3340) DUF3752 PF12572.3 EPS29558.1 - 1.3e-36 126.0 13.2 2.1e-36 125.3 9.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3752) Acetyltransf_1 PF00583.19 EPS29559.1 - 5.1e-15 55.2 0.1 8.4e-15 54.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EPS29559.1 - 2.8e-08 33.9 0.0 3.2e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EPS29559.1 - 3.6e-08 33.4 0.0 4.9e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPS29559.1 - 3.1e-07 30.0 0.0 4.8e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EPS29559.1 - 0.0005 19.9 0.1 0.0011 18.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 EPS29559.1 - 0.00096 19.1 0.0 0.0013 18.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPS29559.1 - 0.0012 18.7 0.1 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EPS29559.1 - 0.0072 16.1 0.0 0.015 15.2 0.0 1.5 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase DUF3749 PF12568.3 EPS29559.1 - 0.02 14.4 0.1 0.029 13.9 0.1 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain He_PIG PF05345.7 EPS29560.1 - 3.2e-17 62.2 4.1 0.00013 21.9 0.0 4.7 4 0 0 4 4 4 4 Putative Ig domain SKG6 PF08693.5 EPS29560.1 - 1.4e-07 30.6 1.4 2.9e-07 29.6 1.0 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Shisa PF13908.1 EPS29560.1 - 0.24 11.5 0.3 0.89 9.7 0.1 1.9 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF3602 PF12223.3 EPS29561.1 - 5.7e-20 71.5 9.9 2.4e-17 63.0 0.7 3.2 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Fungal_trans_2 PF11951.3 EPS29562.1 - 0.0013 17.3 1.7 0.0021 16.7 0.3 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF1793 PF08760.6 EPS29563.1 - 2.4e-38 131.6 0.3 4.7e-38 130.7 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) Velvet PF11754.3 EPS29566.1 - 3.2e-83 278.3 0.0 4e-83 278.0 0.0 1.1 1 0 0 1 1 1 1 Velvet factor Yip1 PF04893.12 EPS29567.1 - 0.0081 15.6 4.6 0.0087 15.5 3.2 1.1 1 0 0 1 1 1 1 Yip1 domain DUF3810 PF12725.2 EPS29567.1 - 1.1 8.1 2.9 1.2 7.9 2.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) AIM24 PF01987.12 EPS29569.1 - 0.045 13.2 0.0 0.062 12.7 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial biogenesis AIM24 WD40 PF00400.27 EPS29570.1 - 7.9e-84 272.8 14.7 3.6e-13 48.8 0.0 8.4 8 1 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 EPS29570.1 - 4.8e-09 36.2 0.1 0.012 15.3 0.0 3.7 2 2 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EPS29570.1 - 1.2e-07 30.2 5.8 0.07 11.2 0.1 5.0 3 2 1 5 5 5 3 Nucleoporin Nup120/160 NLE PF08154.7 EPS29570.1 - 7.1e-05 22.7 0.0 0.00015 21.7 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain FAD_binding_9 PF08021.6 EPS29570.1 - 0.013 15.5 0.0 0.25 11.3 0.0 2.5 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain TFIIIC_delta PF12657.2 EPS29570.1 - 0.029 14.0 0.5 0.82 9.3 0.1 2.8 2 1 0 2 2 2 0 Transcription factor IIIC subunit delta N-term SWIB PF02201.13 EPS29571.1 - 1.5e-24 85.4 0.0 3.1e-24 84.4 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.6 EPS29571.1 - 1.4e-15 56.7 0.3 2.8e-15 55.8 0.2 1.5 1 0 0 1 1 1 1 DEK C terminal domain zf-C3HC4_3 PF13920.1 EPS29572.1 - 3.2e-05 23.4 8.9 3.2e-05 23.4 6.2 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) MutS_V PF00488.16 EPS29573.1 - 1.8e-72 243.5 0.0 2.9e-72 242.8 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EPS29573.1 - 8.1e-37 126.9 1.1 8.1e-37 126.9 0.8 1.8 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 EPS29573.1 - 1.9e-13 50.3 0.0 4.2e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 EPS29573.1 - 5.9e-07 29.6 0.1 2e-06 27.9 0.1 1.9 1 1 0 1 1 1 1 MutS domain II DisA_N PF02457.11 EPS29573.1 - 0.065 12.3 0.3 0.28 10.3 0.4 1.9 2 0 0 2 2 2 0 DisA bacterial checkpoint controller nucleotide-binding eIF2A PF08662.6 EPS29574.1 - 6.5e-40 136.9 7.3 4.4e-37 127.6 2.6 4.2 3 2 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_6 PF14259.1 EPS29574.1 - 5.5e-08 32.6 0.0 1.3e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS29574.1 - 1.6e-07 31.0 0.0 3.8e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPS29574.1 - 7.3e-07 28.7 0.0 1.7e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EPS29574.1 - 0.0008 19.2 0.0 0.3 11.0 0.0 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat Lyase_1 PF00206.15 EPS29574.1 - 0.14 11.3 0.1 0.23 10.6 0.1 1.3 1 0 0 1 1 1 0 Lyase MHC_II_alpha PF00993.15 EPS29574.1 - 1.6 8.3 5.1 6.3 6.4 0.0 2.7 2 0 0 2 2 2 0 Class II histocompatibility antigen, alpha domain CAP PF00188.21 EPS29575.1 - 1.6e-21 77.0 0.2 3.2e-21 76.1 0.1 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Sec10 PF07393.6 EPS29576.1 - 3.3e-177 590.8 0.0 3.7e-177 590.6 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.2 EPS29576.1 - 8e-06 25.4 0.1 2.1e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EPS29576.1 - 0.00013 21.5 0.0 0.0003 20.3 0.0 1.6 1 0 0 1 1 1 1 F-box domain RINT1_TIP1 PF04437.8 EPS29576.1 - 0.0031 16.1 0.1 0.0078 14.8 0.1 1.6 1 0 0 1 1 1 1 RINT-1 / TIP-1 family CDO_I PF05995.7 EPS29577.1 - 1.2e-39 135.2 0.5 1.5e-39 134.9 0.3 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 EPS29577.1 - 4.4e-05 22.9 0.1 6.3e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) Auxin_BP PF02041.11 EPS29577.1 - 0.0045 16.4 0.0 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 Auxin binding protein Fungal_trans PF04082.13 EPS29578.1 - 1.8e-10 40.1 0.1 3.3e-10 39.3 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Herpes_UL95 PF03038.9 EPS29578.1 - 0.084 11.7 0.1 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 UL95 family MinC_N PF05209.8 EPS29578.1 - 0.21 11.3 0.0 1.2 8.9 0.0 2.0 2 0 0 2 2 2 0 Septum formation inhibitor MinC, N-terminal domain SLAC1 PF03595.12 EPS29579.1 - 8.8e-103 343.4 55.7 9.9e-103 343.2 38.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF3043 PF11241.3 EPS29579.1 - 0.88 9.1 0.0 0.88 9.1 0.0 3.1 3 1 1 5 5 5 0 Protein of unknown function (DUF3043) Cytochrom_C1 PF02167.10 EPS29580.1 - 7e-79 264.5 0.0 9.1e-79 264.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 EPS29580.1 - 0.0079 16.3 0.0 0.018 15.1 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III SNARE_assoc PF09335.6 EPS29580.1 - 0.069 13.3 0.6 0.17 12.0 0.1 1.8 2 0 0 2 2 2 0 SNARE associated Golgi protein Cytochrom_C PF00034.16 EPS29580.1 - 0.13 13.1 0.3 0.6 10.9 0.1 2.3 2 1 0 2 2 2 0 Cytochrome c AIG2_2 PF13772.1 EPS29581.1 - 6e-06 26.2 0.0 4.1e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 AIG2-like family DAHP_synth_1 PF00793.15 EPS29583.1 - 9.4e-101 336.0 0.0 1.1e-100 335.7 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family F-box-like PF12937.2 EPS29584.1 - 0.00037 20.1 0.1 0.001 18.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like hDGE_amylase PF14701.1 EPS29585.1 - 4.5e-182 605.6 0.0 5.8e-182 605.3 0.0 1.1 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 EPS29585.1 - 2.6e-113 378.5 0.1 8.5e-113 376.8 0.0 1.8 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 EPS29585.1 - 3.9e-89 298.2 0.0 5.9e-89 297.6 0.0 1.3 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 EPS29585.1 - 2.3e-26 91.4 0.1 5.4e-26 90.2 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 EPS29585.1 - 0.00012 21.5 0.1 0.0072 15.7 0.0 2.4 2 0 0 2 2 2 1 Alpha amylase, catalytic domain DUF2868 PF11067.3 EPS29586.1 - 0.045 12.8 0.2 0.052 12.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) NAD_Gly3P_dh_N PF01210.18 EPS29587.1 - 7.5e-48 162.2 0.1 1.8e-47 160.9 0.0 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 EPS29587.1 - 3.9e-45 153.2 0.1 5.6e-45 152.7 0.1 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 EPS29587.1 - 0.016 15.6 0.0 1.6 9.2 0.0 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Pox_VLTF3 PF04947.9 EPS29587.1 - 0.072 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like SLX9 PF15341.1 EPS29588.1 - 5.5e-34 117.2 9.8 6.5e-34 116.9 6.8 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 HrpJ PF07201.6 EPS29588.1 - 0.012 15.6 1.1 0.018 15.0 0.7 1.2 1 0 0 1 1 1 0 HrpJ-like domain DegV PF02645.11 EPS29588.1 - 0.098 11.7 0.8 0.12 11.4 0.1 1.5 2 0 0 2 2 2 0 Uncharacterised protein, DegV family COG1307 DUF3347 PF11827.3 EPS29588.1 - 0.13 12.2 1.8 0.15 12.0 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) Calpain_inhib PF00748.14 EPS29588.1 - 0.58 10.5 5.0 0.38 11.0 2.1 1.7 1 1 0 1 1 1 0 Calpain inhibitor NAD_binding_10 PF13460.1 EPS29589.1 - 5.4e-07 29.7 0.0 6.9e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPS29589.1 - 0.0064 15.9 0.0 0.0088 15.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DFF40 PF09230.5 EPS29589.1 - 0.14 11.5 0.0 0.32 10.3 0.0 1.5 1 1 0 1 1 1 0 DNA fragmentation factor 40 kDa NAD_binding_4 PF07993.7 EPS29589.1 - 0.14 11.0 0.1 0.3 9.9 0.0 1.6 1 1 0 1 1 1 0 Male sterility protein FAD_binding_4 PF01565.18 EPS29590.1 - 1.7e-19 69.6 2.2 1.9e-19 69.5 0.5 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EPS29590.1 - 2.6e-10 40.0 0.1 5e-10 39.1 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like AAA_2 PF07724.9 EPS29591.1 - 2.8e-37 128.2 0.0 2.5e-36 125.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EPS29591.1 - 1e-14 54.8 0.0 1.9e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EPS29591.1 - 3.1e-09 36.6 0.2 1.4e-08 34.4 0.0 2.0 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EPS29591.1 - 3.4e-06 26.8 0.0 1.2e-05 25.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EPS29591.1 - 0.00014 22.0 0.2 0.003 17.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EPS29591.1 - 0.0002 20.6 0.3 0.01 15.0 0.0 3.0 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EPS29591.1 - 0.00039 19.9 0.0 0.085 12.3 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.1 EPS29591.1 - 0.00064 19.7 0.7 0.0023 17.9 0.1 2.1 1 1 1 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 EPS29591.1 - 0.0011 18.4 0.0 0.0021 17.5 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 EPS29591.1 - 0.0022 18.8 0.0 0.0055 17.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EPS29591.1 - 0.0039 16.8 0.1 0.0089 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EPS29591.1 - 0.01 14.9 0.2 0.11 11.5 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EPS29591.1 - 0.026 14.4 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EPS29591.1 - 0.035 13.5 0.0 0.072 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EPS29591.1 - 0.038 14.1 0.0 0.094 12.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 EPS29591.1 - 0.078 12.5 0.0 0.21 11.1 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EPS29591.1 - 0.081 12.5 0.3 0.97 9.0 0.2 2.3 1 1 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 EPS29591.1 - 0.14 12.4 0.1 0.44 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EPS29591.1 - 0.15 11.2 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 EPS29591.1 - 0.15 11.6 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Chromo PF00385.19 EPS29592.1 - 1.4e-09 37.5 0.5 2.7e-09 36.5 0.3 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.1 EPS29592.1 - 0.014 15.2 0.2 0.028 14.2 0.1 1.5 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 AMP-binding PF00501.23 EPS29593.1 - 2.1e-237 787.3 0.0 2.4e-83 279.8 0.0 3.2 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 EPS29593.1 - 2.9e-117 390.8 3.5 1e-29 103.3 0.0 9.0 7 3 1 8 8 8 7 Condensation domain PP-binding PF00550.20 EPS29593.1 - 3.8e-34 116.7 4.9 1.1e-11 44.7 0.0 4.0 3 0 0 3 3 3 3 Phosphopantetheine attachment site GH3 PF03321.8 EPS29593.1 - 7.2e-07 28.1 0.9 0.022 13.2 0.0 3.8 4 0 0 4 4 4 3 GH3 auxin-responsive promoter MFS_1 PF07690.11 EPS29594.1 - 1.1e-40 139.5 50.1 1.2e-38 132.7 23.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS29594.1 - 1.1e-14 53.9 10.3 1.1e-14 53.9 7.1 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 EPS29594.1 - 7.5e-07 27.7 11.9 1.2e-06 27.0 6.0 2.4 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EPS29594.1 - 0.0014 16.8 3.8 0.0014 16.8 2.6 1.6 1 1 0 1 1 1 1 Transmembrane secretion effector MFS_1 PF07690.11 EPS29595.1 - 1.4e-16 60.1 37.9 1.4e-16 60.1 26.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ras PF00071.17 EPS29596.1 - 1.1e-63 213.4 0.2 1.3e-63 213.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPS29596.1 - 1.8e-21 76.8 0.1 2.5e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPS29596.1 - 2.4e-13 49.6 0.1 3.1e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EPS29596.1 - 5.1e-08 32.8 0.1 7.7e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EPS29596.1 - 5.9e-05 22.3 0.1 0.0001 21.5 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EPS29596.1 - 6.7e-05 22.4 0.1 0.00022 20.7 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EPS29596.1 - 0.00013 22.0 0.0 0.00036 20.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 EPS29596.1 - 0.0011 18.1 0.1 0.0014 17.7 0.1 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 EPS29596.1 - 0.0012 18.7 0.1 0.003 17.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EPS29596.1 - 0.0026 16.9 0.1 0.0055 15.9 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SRPRB PF09439.5 EPS29596.1 - 0.015 14.5 0.0 0.022 13.9 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 EPS29596.1 - 0.018 15.0 0.3 0.038 13.9 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 EPS29596.1 - 0.018 15.3 0.1 0.028 14.7 0.1 1.4 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.1 EPS29596.1 - 0.023 14.2 0.1 0.04 13.4 0.1 1.5 1 1 0 1 1 1 0 AAA domain DUF4468 PF14730.1 EPS29596.1 - 0.054 13.1 0.1 0.18 11.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4468) with TBP-like fold FeoB_N PF02421.13 EPS29596.1 - 0.077 12.2 0.1 0.22 10.8 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B SpoIIID PF12116.3 EPS29596.1 - 0.078 12.9 0.1 1 9.3 0.0 2.1 2 0 0 2 2 2 0 Stage III sporulation protein D AAA_29 PF13555.1 EPS29596.1 - 0.1 12.1 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EPS29596.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Brix PF04427.13 EPS29597.1 - 2.9e-31 108.6 0.0 3.7e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Brix domain DUF688 PF05097.7 EPS29597.1 - 0.12 11.3 1.1 0.17 10.8 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF688) PfkB PF00294.19 EPS29598.1 - 1.7e-14 53.6 0.0 7.7e-14 51.5 0.0 1.8 1 1 0 1 1 1 1 pfkB family carbohydrate kinase DUF1400 PF07176.6 EPS29598.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1400) Glu-tRNAGln PF02686.10 EPS29599.1 - 0.1 12.4 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit DUF3410 PF11890.3 EPS29600.1 - 0.0063 16.1 0.1 0.0092 15.6 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3410) UPF0193 PF05250.6 EPS29600.1 - 0.022 14.3 1.6 0.028 13.9 1.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0193) Prothymosin PF03247.9 EPS29600.1 - 0.41 10.8 7.8 0.73 10.0 5.4 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family Abp2 PF09441.5 EPS29602.1 - 3.1e-88 294.2 0.1 5.4e-88 293.4 0.0 1.4 1 0 0 1 1 1 1 ARS binding protein 2 TENA_THI-4 PF03070.11 EPS29602.1 - 0.09 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 TENA/THI-4/PQQC family Surfac_D-trimer PF09006.6 EPS29602.1 - 0.29 10.9 1.6 0.59 9.9 1.1 1.5 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation LRR_4 PF12799.2 EPS29603.1 - 0.0019 17.7 1.3 2.7 7.7 1.5 3.0 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) F-box-like PF12937.2 EPS29603.1 - 0.081 12.6 0.8 0.18 11.5 0.6 1.6 1 0 0 1 1 1 0 F-box-like WW PF00397.21 EPS29604.1 - 0.00031 20.5 2.5 0.00085 19.1 1.8 1.8 1 0 0 1 1 1 1 WW domain ORC6 PF05460.8 EPS29607.1 - 0.068 12.2 5.2 0.078 12.0 3.6 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Fungal_trans PF04082.13 EPS29609.1 - 3.5e-08 32.6 0.1 8.3e-08 31.4 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EPS29609.1 - 8.8e-07 28.9 13.8 0.00042 20.4 0.4 3.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EPS29609.1 - 6.3e-05 23.0 14.3 0.00012 22.2 3.5 3.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EPS29609.1 - 0.00065 19.8 18.1 0.13 12.6 0.9 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EPS29609.1 - 0.012 15.4 8.4 0.5 10.3 0.1 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EPS29609.1 - 0.038 14.1 5.1 4.8 7.4 0.9 3.4 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EPS29609.1 - 0.58 10.4 6.0 0.39 10.9 0.4 3.3 4 0 0 4 4 4 0 Zinc-finger of C2H2 type FAA_hydrolase PF01557.13 EPS29610.1 - 1.3e-49 168.6 0.0 1.7e-49 168.2 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family B12-binding PF02310.14 EPS29611.1 - 0.0022 17.8 0.1 0.0031 17.3 0.1 1.2 1 0 0 1 1 1 1 B12 binding domain DUF1388 PF07142.7 EPS29612.1 - 0.07 12.8 0.2 0.094 12.4 0.2 1.2 1 0 0 1 1 1 0 Repeat of unknown function (DUF1388) ETX_MTX2 PF03318.8 EPS29613.1 - 6e-12 45.5 7.4 8.5e-12 45.1 5.1 1.2 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Aerolysin PF01117.15 EPS29613.1 - 1.8e-05 23.8 0.6 2.4e-05 23.4 0.4 1.1 1 0 0 1 1 1 1 Aerolysin toxin Fmp27_GFWDK PF10347.4 EPS29613.1 - 0.031 14.2 0.1 0.055 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain NmrA PF05368.8 EPS29614.1 - 1.5e-12 47.2 0.0 3.9e-12 45.9 0.0 1.6 1 1 1 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 EPS29614.1 - 1.4e-09 38.1 0.3 2.1e-09 37.6 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EPS29614.1 - 0.0022 18.2 0.1 0.0037 17.5 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 EPS29614.1 - 0.01 16.3 0.1 0.02 15.4 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.15 EPS29614.1 - 0.026 14.4 0.2 0.14 12.1 0.2 2.1 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.5 EPS29614.1 - 0.033 13.8 0.4 0.064 12.9 0.2 1.6 1 1 0 1 1 1 0 KR domain CPSase_L_chain PF00289.17 EPS29614.1 - 0.062 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Epimerase PF01370.16 EPS29614.1 - 0.092 12.1 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family EHN PF06441.7 EPS29616.1 - 1.5e-35 121.5 0.9 7e-35 119.3 0.1 2.1 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EPS29616.1 - 4.1e-08 33.3 3.0 1.3e-07 31.7 2.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPS29616.1 - 7.9e-05 22.3 0.0 0.00024 20.7 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EPS29617.1 - 1.1e-32 113.7 0.0 1.4e-32 113.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPS29617.1 - 1.2e-16 60.9 0.0 3.4e-16 59.5 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPS29617.1 - 1.6e-15 57.1 0.0 2.7e-15 56.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EPS29617.1 - 2.9e-10 40.1 0.0 3.9e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 EPS29617.1 - 3.2e-07 30.8 0.0 4.1e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Ndr PF03096.9 EPS29617.1 - 0.00099 17.6 0.0 0.0017 16.9 0.0 1.4 1 1 0 1 1 1 1 Ndr family Abhydrolase_3 PF07859.8 EPS29617.1 - 0.0012 18.4 0.0 0.0017 17.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EPS29617.1 - 0.0059 16.0 0.0 0.014 14.8 0.0 1.7 2 0 0 2 2 2 1 Putative esterase DUF2048 PF09752.4 EPS29617.1 - 0.0072 15.2 0.0 0.019 13.8 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2048) Lipase_3 PF01764.20 EPS29617.1 - 0.014 15.0 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Ser_hydrolase PF06821.8 EPS29617.1 - 0.014 14.9 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase DUF676 PF05057.9 EPS29617.1 - 0.018 14.3 0.0 0.029 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_2 PF02230.11 EPS29617.1 - 0.031 13.7 0.0 0.37 10.1 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase LCAT PF02450.10 EPS29617.1 - 0.053 12.4 0.1 0.079 11.9 0.1 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF915 PF06028.6 EPS29617.1 - 0.057 12.5 0.1 4.7 6.2 0.0 2.9 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) DUF2305 PF10230.4 EPS29617.1 - 0.099 12.0 0.0 0.28 10.5 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Cutinase PF01083.17 EPS29617.1 - 0.11 12.1 0.1 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 Cutinase NPV_P10 PF05531.7 EPS29618.1 - 0.00014 22.0 16.7 0.83 9.9 0.1 6.9 5 1 2 7 7 7 3 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.7 EPS29618.1 - 0.014 15.1 22.8 1.6 8.5 0.5 6.1 4 3 2 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 EPS29618.1 - 5.2 6.8 22.7 0.18 11.6 0.5 5.8 3 3 3 6 6 6 0 Protein of unknown function (DUF1664) TIP49 PF06068.8 EPS29619.1 - 2.4e-174 579.7 5.1 2.8e-174 579.4 3.5 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EPS29619.1 - 1.2e-08 35.1 2.1 1.1e-05 25.6 0.0 3.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EPS29619.1 - 5.6e-08 32.1 1.6 2.7e-05 23.3 0.0 2.6 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus DnaB_C PF03796.10 EPS29619.1 - 3e-06 26.2 0.6 5.4e-06 25.4 0.4 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.1 EPS29619.1 - 1.1e-05 25.4 0.0 0.00017 21.6 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EPS29619.1 - 6e-05 23.1 0.0 0.073 13.2 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_14 PF13173.1 EPS29619.1 - 0.0011 18.8 0.0 1.4 8.8 0.0 2.7 3 0 0 3 3 3 2 AAA domain Mg_chelatase PF01078.16 EPS29619.1 - 0.0021 17.2 1.0 0.029 13.5 0.4 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EPS29619.1 - 0.0027 17.1 0.1 0.006 16.0 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EPS29619.1 - 0.0035 17.0 0.2 0.4 10.3 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EPS29619.1 - 0.0075 15.7 0.1 3.2 7.1 0.1 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_19 PF13245.1 EPS29619.1 - 0.011 15.4 1.5 0.065 13.0 0.1 2.7 2 2 0 2 2 2 0 Part of AAA domain AAA_11 PF13086.1 EPS29619.1 - 0.06 12.9 0.3 0.15 11.6 0.2 1.5 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 EPS29619.1 - 0.062 12.1 0.0 0.099 11.4 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.1 EPS29619.1 - 0.13 12.1 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain GYF PF02213.11 EPS29620.1 - 2.8e-13 49.2 0.3 5.8e-13 48.2 0.2 1.6 1 0 0 1 1 1 1 GYF domain UFD1 PF03152.9 EPS29621.1 - 4.2e-76 253.9 0.0 5.4e-76 253.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 EPS29621.1 - 0.016 14.7 0.0 0.076 12.6 0.0 2.0 1 1 1 2 2 2 0 Cell division protein 48 (CDC48), domain 2 DUF829 PF05705.9 EPS29622.1 - 8.7e-57 192.5 0.1 1e-56 192.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DUF4246 PF14033.1 EPS29623.1 - 2.7e-142 474.9 0.0 3.4e-142 474.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) DNA_processg_A PF02481.10 EPS29623.1 - 0.19 10.5 0.0 0.33 9.8 0.0 1.3 1 0 0 1 1 1 0 DNA recombination-mediator protein A RNA_pol_Rpb2_6 PF00562.23 EPS29624.1 - 6.3e-119 397.1 0.1 1.3e-118 396.1 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EPS29624.1 - 3.9e-54 182.6 1.4 4.7e-54 182.3 0.2 1.7 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 EPS29624.1 - 4.4e-29 100.5 0.1 1.3e-28 99.0 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 EPS29624.1 - 6.9e-29 100.6 1.9 1.4e-28 99.6 1.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 EPS29624.1 - 9e-21 73.4 0.4 2.9e-20 71.8 0.3 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EPS29624.1 - 9.7e-20 70.1 0.4 3.2e-19 68.4 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EPS29624.1 - 1.3e-12 47.4 0.6 2.7e-12 46.4 0.5 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 PUF PF00806.14 EPS29625.1 - 8.3e-59 191.8 6.5 7.9e-07 28.2 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Lge1 PF11488.3 EPS29625.1 - 0.061 13.5 0.4 0.15 12.2 0.3 1.6 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 ORC5_C PF14630.1 EPS29626.1 - 5.9e-92 307.9 0.0 7.5e-92 307.6 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 EPS29626.1 - 5.8e-15 55.7 0.2 1.6e-14 54.2 0.2 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EPS29626.1 - 0.00049 20.2 0.0 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EPS29626.1 - 0.0073 16.4 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EPS29626.1 - 0.1 12.4 0.4 0.39 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain WD40 PF00400.27 EPS29627.1 - 0.0067 16.2 0.1 9.4 6.2 0.0 3.4 4 0 0 4 4 4 2 WD domain, G-beta repeat EF-hand_4 PF12763.2 EPS29628.1 - 4.1e-36 122.8 0.0 1.8e-13 50.1 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EPS29628.1 - 4.9e-11 42.6 0.0 1.7e-06 28.0 0.0 4.1 3 1 1 4 4 4 1 EF-hand domain pair UBA PF00627.26 EPS29628.1 - 1.5e-08 34.1 0.0 3.1e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_1 PF00036.27 EPS29628.1 - 1.5e-07 30.1 0.1 0.0031 16.7 0.0 4.8 5 0 0 5 5 5 1 EF hand EF-hand_8 PF13833.1 EPS29628.1 - 5.7e-05 22.6 0.0 0.016 14.8 0.0 3.7 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_6 PF13405.1 EPS29628.1 - 0.00025 20.6 2.1 3.3 7.8 0.0 5.4 6 0 0 6 6 5 1 EF-hand domain Myosin_tail_1 PF01576.14 EPS29628.1 - 0.0033 15.2 24.3 0.0046 14.7 16.9 1.1 1 0 0 1 1 1 1 Myosin tail GAS PF13851.1 EPS29628.1 - 0.0033 16.6 23.8 0.04 13.1 7.0 2.3 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.7 EPS29628.1 - 0.025 14.2 26.9 12 5.6 18.7 2.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF960 PF06124.6 EPS29628.1 - 0.072 13.3 0.0 60 3.9 0.0 3.2 3 0 0 3 3 3 0 Staphylococcal protein of unknown function (DUF960) Spc7 PF08317.6 EPS29628.1 - 0.17 10.4 22.2 0.25 9.9 4.1 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF3584 PF12128.3 EPS29628.1 - 0.22 8.7 22.8 0.3 8.3 15.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_13 PF13166.1 EPS29628.1 - 0.48 8.8 16.7 0.76 8.1 11.6 1.2 1 0 0 1 1 1 0 AAA domain COG2 PF06148.6 EPS29628.1 - 0.74 9.6 10.5 2.5 7.9 0.6 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CENP-F_leu_zip PF10473.4 EPS29628.1 - 5.4 6.8 24.3 0.2 11.5 4.2 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Mod_r PF07200.8 EPS29628.1 - 6.9 6.5 22.4 0.85 9.5 9.7 2.3 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein IFT57 PF10498.4 EPS29628.1 - 8 5.0 15.7 21 3.6 10.7 1.7 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 TMF_TATA_bd PF12325.3 EPS29628.1 - 8.7 6.1 22.7 1.9 8.2 2.0 3.6 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding ADIP PF11559.3 EPS29628.1 - 9.6 6.0 26.4 0.99 9.2 6.8 3.0 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 EPS29628.1 - 9.8 5.7 28.3 5.4e+02 -0.0 19.6 2.3 1 1 0 1 1 1 0 IncA protein Tubulin PF00091.20 EPS29629.1 - 1.3e-70 237.5 0.0 1.8e-70 237.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EPS29629.1 - 2.5e-48 163.2 0.0 6.2e-48 162.0 0.0 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EPS29629.1 - 0.002 17.6 0.0 0.0041 16.6 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Pga1 PF10333.4 EPS29630.1 - 0.073 12.7 0.2 0.3 10.7 0.0 2.0 2 0 0 2 2 2 0 GPI-Mannosyltransferase II co-activator tRNA-synt_2 PF00152.15 EPS29631.1 - 1.8e-76 257.0 0.0 2.7e-76 256.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 EPS29631.1 - 3.1e-18 65.6 0.0 4.3e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA-synt_2d PF01409.15 EPS29631.1 - 0.0027 16.9 0.1 0.62 9.2 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 EPS29631.1 - 0.011 15.6 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Abhydrolase_3 PF07859.8 EPS29633.1 - 1e-44 152.6 0.1 1.6e-44 152.0 0.1 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EPS29633.1 - 0.0001 21.2 0.8 0.00021 20.1 0.6 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EPS29633.1 - 0.0014 18.4 0.3 0.0017 18.1 0.2 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EPS29633.1 - 0.0043 16.2 0.2 0.78 8.9 0.0 2.5 3 0 0 3 3 3 2 Prolyl oligopeptidase family DUF2974 PF11187.3 EPS29633.1 - 0.063 12.6 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) RRN3 PF05327.6 EPS29634.1 - 2.9e-170 567.1 0.1 8.9e-170 565.5 0.0 1.7 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 Beach PF02138.13 EPS29634.1 - 0.057 12.8 0.1 0.15 11.4 0.0 1.6 2 0 0 2 2 2 0 Beige/BEACH domain Fungal_trans PF04082.13 EPS29636.1 - 8e-22 77.3 0.4 3.7e-21 75.1 0.2 2.2 2 1 0 2 2 2 1 Fungal specific transcription factor domain Iso_dh PF00180.15 EPS29637.1 - 7.2e-86 288.2 0.0 8.2e-86 288.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Gp_dh_C PF02800.15 EPS29638.1 - 2.1e-57 192.9 0.0 3e-57 192.4 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EPS29638.1 - 2.5e-49 167.1 0.0 4.4e-49 166.3 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EPS29638.1 - 0.0044 16.2 0.0 0.0089 15.2 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DapB_N PF01113.15 EPS29638.1 - 0.021 14.7 0.1 0.086 12.7 0.0 2.0 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus WD40 PF00400.27 EPS29639.1 - 4.8e-25 86.4 9.3 1.5e-06 27.8 0.2 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 EPS29639.1 - 2.9e-05 22.4 1.1 0.0053 14.9 0.1 2.8 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Caldesmon PF02029.10 EPS29639.1 - 0.00025 19.6 2.8 0.00031 19.2 2.0 1.2 1 0 0 1 1 1 1 Caldesmon Nucleoporin_N PF08801.6 EPS29639.1 - 0.053 12.2 0.1 3.3 6.3 0.0 3.0 2 1 0 2 2 2 0 Nup133 N terminal like Cmc1 PF08583.5 EPS29640.1 - 2.9e-17 62.1 3.4 3.8e-17 61.8 2.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Phage_HK97_TLTM PF06120.6 EPS29640.1 - 0.026 13.8 0.9 0.032 13.5 0.6 1.1 1 0 0 1 1 1 0 Tail length tape measure protein GCK PF07802.6 EPS29640.1 - 0.78 9.9 2.9 2.4 8.3 1.2 1.9 1 1 1 2 2 2 0 GCK domain Fcf1 PF04900.7 EPS29641.1 - 1.2e-12 47.7 0.4 5.5e-05 23.1 0.1 3.0 2 1 0 2 2 2 2 Fcf1 SpoIIE PF07228.7 EPS29642.1 - 0.00019 21.2 0.0 0.00096 18.9 0.0 2.1 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EPS29642.1 - 0.00025 20.5 0.1 0.66 9.3 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EPS29642.1 - 0.0021 17.4 0.1 0.003 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C P34-Arc PF04045.9 EPS29644.1 - 3.8e-105 350.5 0.3 4.5e-105 350.2 0.2 1.0 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.7 EPS29644.1 - 0.081 12.3 0.4 0.18 11.2 0.3 1.5 1 1 0 1 1 1 0 ARP2/3 complex 20 kDa subunit (ARPC4) WD40 PF00400.27 EPS29645.1 - 3.3e-74 242.3 20.8 2.9e-10 39.6 0.1 10.9 10 0 0 10 10 10 10 WD domain, G-beta repeat Utp12 PF04003.7 EPS29645.1 - 4.5e-20 71.5 0.5 7.5e-20 70.8 0.4 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 EPS29645.1 - 3e-06 25.6 4.6 0.062 11.4 0.0 5.1 4 2 0 5 5 5 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EPS29645.1 - 0.00034 20.1 1.0 0.33 10.3 0.0 2.7 2 0 0 2 2 2 2 PQQ-like domain DUF3312 PF11768.3 EPS29645.1 - 0.00094 17.5 0.0 0.014 13.6 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF3312) Nucleoporin_N PF08801.6 EPS29645.1 - 0.0063 15.3 3.4 0.25 10.0 0.1 4.2 2 2 0 4 4 4 1 Nup133 N terminal like WLM PF08325.5 EPS29646.1 - 2.1e-60 203.7 0.1 3.4e-60 203.0 0.1 1.3 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.13 EPS29646.1 - 7.2e-05 21.8 5.3 7.2e-05 21.8 3.7 3.3 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others DZR PF12773.2 EPS29646.1 - 0.0019 17.9 11.3 0.19 11.5 0.5 2.5 2 0 0 2 2 2 2 Double zinc ribbon DUF45 PF01863.12 EPS29646.1 - 0.003 17.3 2.4 0.003 17.3 1.7 1.8 2 0 0 2 2 2 1 Protein of unknown function DUF45 C1_1 PF00130.17 EPS29646.1 - 0.013 15.1 2.9 0.013 15.1 2.0 2.6 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SprT-like PF10263.4 EPS29646.1 - 0.014 15.0 0.1 0.014 15.0 0.0 2.8 2 1 0 2 2 2 0 SprT-like family DUF1776 PF08643.5 EPS29647.1 - 1.5e-99 332.9 0.0 1.8e-99 332.6 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DUF1686 PF07937.6 EPS29647.1 - 0.097 12.2 0.0 2.7 7.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1686) Far-17a_AIG1 PF04750.9 EPS29648.1 - 2.8e-06 26.6 19.9 4.8e-06 25.8 13.7 1.5 1 1 0 1 1 1 1 FAR-17a/AIG1-like protein DUF4381 PF14316.1 EPS29648.1 - 6.3 6.8 10.1 2.2 8.4 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) Sel1 PF08238.7 EPS29650.1 - 5.8e-13 49.0 8.2 0.00096 19.7 0.8 4.2 4 0 0 4 4 4 3 Sel1 repeat HCMV_UL139 PF12507.3 EPS29651.1 - 0.02 15.0 0.7 0.031 14.4 0.5 1.3 1 0 0 1 1 1 0 Human Cytomegalovirus UL139 protein DUF3712 PF12505.3 EPS29652.1 - 7.4e-34 116.4 0.3 1.7e-33 115.2 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) LEA_2 PF03168.8 EPS29652.1 - 0.023 15.0 0.7 8.4 6.8 0.1 2.4 2 0 0 2 2 2 0 Late embryogenesis abundant protein ESSS PF10183.4 EPS29652.1 - 0.027 14.8 0.1 0.053 13.9 0.1 1.4 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF805 PF05656.9 EPS29652.1 - 0.086 12.6 0.5 0.16 11.8 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF805) DUF1279 PF06916.8 EPS29652.1 - 0.12 12.6 0.6 0.21 11.8 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1279) MFS_1 PF07690.11 EPS29653.1 - 4.3e-29 101.3 40.2 3.4e-24 85.2 12.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.20 EPS29654.1 - 5.5e-18 65.4 0.0 9.2e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPS29654.1 - 5.2e-09 36.2 0.0 9.6e-09 35.3 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPS29654.1 - 5.3e-06 26.2 0.1 3.2e-05 23.6 0.0 2.3 2 1 0 2 2 2 1 KR domain Epimerase PF01370.16 EPS29654.1 - 0.00052 19.5 0.0 0.00086 18.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EPS29654.1 - 0.053 13.5 0.0 0.072 13.0 0.0 1.6 1 1 0 1 1 1 0 NADH(P)-binding FAD_binding_3 PF01494.14 EPS29655.1 - 9.6e-14 51.1 5.2 4.1e-12 45.8 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EPS29655.1 - 0.00046 20.1 1.3 0.0013 18.7 0.9 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EPS29655.1 - 0.0005 19.0 0.6 0.013 14.4 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase SE PF08491.5 EPS29655.1 - 0.012 14.4 0.0 0.49 9.1 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase NAD_binding_9 PF13454.1 EPS29655.1 - 0.023 14.4 1.2 1.1 8.9 0.4 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EPS29655.1 - 0.086 12.7 0.1 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPS29655.1 - 0.099 12.6 0.7 1.1 9.3 0.2 2.6 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPS29655.1 - 0.24 11.8 1.2 14 6.2 1.4 2.6 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EPS29655.1 - 0.68 8.4 2.8 1.2 7.6 0.0 2.2 2 1 0 2 2 2 0 Tryptophan halogenase AAA_11 PF13086.1 EPS29659.1 - 1.8e-62 211.0 0.7 3.2e-62 210.1 0.5 1.4 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 EPS29659.1 - 6.7e-57 192.1 0.0 2.7e-56 190.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EPS29659.1 - 1.6e-12 46.9 0.1 5.8e-12 45.1 0.0 2.0 2 0 0 2 2 1 1 Part of AAA domain AAA_30 PF13604.1 EPS29659.1 - 2.2e-12 46.9 0.1 1.8e-10 40.7 0.1 2.7 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EPS29659.1 - 2.7e-08 33.6 0.1 0.019 14.5 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 EPS29659.1 - 1.3e-06 27.6 0.7 1.5e-05 24.1 0.5 2.2 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 EPS29659.1 - 2.9e-06 26.6 0.0 0.015 14.4 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein ResIII PF04851.10 EPS29659.1 - 3.9e-06 26.8 0.0 9.8e-06 25.5 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 EPS29659.1 - 9.5e-06 25.1 1.2 2.2e-05 23.9 0.1 2.0 1 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.9 EPS29659.1 - 1.2e-05 25.0 0.1 0.002 17.7 0.1 2.4 1 1 0 1 1 1 1 Helicase AAA_22 PF13401.1 EPS29659.1 - 1.3e-05 25.3 0.2 0.00035 20.7 0.1 2.5 1 1 0 1 1 1 1 AAA domain DEAD PF00270.24 EPS29659.1 - 4.7e-05 22.9 0.2 0.00054 19.4 0.1 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase UvrD_C PF13361.1 EPS29659.1 - 0.00058 19.4 0.1 0.2 11.0 0.0 2.9 2 1 1 3 3 3 1 UvrD-like helicase C-terminal domain T2SE PF00437.15 EPS29659.1 - 0.0011 17.8 0.0 0.0024 16.8 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Flavi_DEAD PF07652.9 EPS29659.1 - 0.002 17.9 1.7 0.0061 16.3 0.1 2.5 3 0 0 3 3 3 1 Flavivirus DEAD domain TrwB_AAD_bind PF10412.4 EPS29659.1 - 0.0027 16.4 0.0 0.0048 15.5 0.0 1.3 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain Zot PF05707.7 EPS29659.1 - 0.0031 16.9 0.1 0.012 15.0 0.0 2.1 3 0 0 3 3 3 1 Zonular occludens toxin (Zot) AAA_16 PF13191.1 EPS29659.1 - 0.0066 16.4 0.0 0.021 14.8 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 EPS29659.1 - 0.0066 15.8 0.0 0.024 14.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EPS29659.1 - 0.0066 15.8 0.0 0.029 13.8 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_5 PF07728.9 EPS29659.1 - 0.0074 16.0 0.0 0.057 13.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.24 EPS29659.1 - 0.008 16.3 0.4 0.053 13.7 0.2 2.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CbiA PF01656.18 EPS29659.1 - 0.026 13.9 0.3 0.15 11.4 0.2 2.2 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain FtsK_SpoIIIE PF01580.13 EPS29659.1 - 0.032 13.6 0.3 0.51 9.7 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family PIF1 PF05970.9 EPS29659.1 - 0.042 12.7 0.0 3.5 6.4 0.0 2.4 2 1 0 2 2 2 0 PIF1-like helicase UvrD_C_2 PF13538.1 EPS29659.1 - 0.054 13.6 0.0 7.2 6.8 0.0 2.8 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain SRP54 PF00448.17 EPS29659.1 - 0.064 12.6 0.0 4.7 6.5 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain 4HB_MCP_1 PF12729.2 EPS29659.1 - 0.071 12.4 0.2 0.071 12.4 0.2 1.5 2 0 0 2 2 1 0 Four helix bundle sensory module for signal transduction TK PF00265.13 EPS29659.1 - 0.18 11.3 0.1 2.5 7.6 0.0 2.3 2 0 0 2 2 2 0 Thymidine kinase HhH-GPD PF00730.20 EPS29660.1 - 7.1e-17 61.6 0.0 2.6e-16 59.8 0.0 2.0 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EPS29660.1 - 1.4e-07 30.8 0.0 5.9e-07 28.8 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif DUF2664 PF10867.3 EPS29660.1 - 0.089 13.4 0.2 0.28 11.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2664) UQ_con PF00179.21 EPS29661.1 - 2.1e-41 140.6 0.0 2.3e-41 140.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EPS29661.1 - 5.7e-05 22.8 0.0 0.0001 22.0 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EPS29661.1 - 0.039 13.8 0.5 0.051 13.4 0.4 1.5 1 1 0 1 1 1 0 RWD domain 1-cysPrx_C PF10417.4 EPS29663.1 - 0.14 11.8 0.3 0.26 10.9 0.2 1.5 1 0 0 1 1 1 0 C-terminal domain of 1-Cys peroxiredoxin Tyrosinase PF00264.15 EPS29664.1 - 4.6e-48 164.3 1.8 5.6e-48 164.0 1.3 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase PBP PF01161.15 EPS29665.1 - 1.9e-23 82.9 0.0 2.4e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein FA_hydroxylase PF04116.8 EPS29666.1 - 2.6e-16 60.0 16.4 2.6e-16 60.0 11.4 2.0 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Hemocyanin_C PF03723.9 EPS29666.1 - 0.86 8.6 2.6 0.38 9.8 0.1 1.5 2 0 0 2 2 2 0 Hemocyanin, ig-like domain GED PF02212.13 EPS29667.1 - 0.089 12.6 1.5 1.8 8.5 1.1 2.4 1 1 0 1 1 1 0 Dynamin GTPase effector domain Glyco_hydro_72 PF03198.9 EPS29668.1 - 2.3e-134 447.3 3.0 2.8e-134 447.0 2.1 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EPS29668.1 - 2.8e-06 26.7 0.1 3.3e-05 23.2 0.1 2.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) HMGL-like PF00682.14 EPS29669.1 - 8.5e-41 140.1 0.0 1.1e-40 139.8 0.0 1.1 1 0 0 1 1 1 1 HMGL-like Copper-fist PF00649.13 EPS29671.1 - 4.4e-23 80.1 2.8 7.7e-23 79.4 1.9 1.4 1 0 0 1 1 1 1 Copper fist DNA binding domain SH3_9 PF14604.1 EPS29672.1 - 4.8e-24 83.6 0.5 7.4e-13 47.8 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.18 EPS29672.1 - 5.5e-23 80.9 2.2 1.4e-22 79.6 0.0 2.6 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 EPS29672.1 - 2.2e-18 65.3 0.9 7.7e-09 34.8 0.0 2.7 3 0 0 3 3 3 2 SH3 domain C1_1 PF00130.17 EPS29672.1 - 1.3e-14 53.6 5.0 2.2e-14 52.8 3.5 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_2 PF07653.12 EPS29672.1 - 8.6e-07 28.3 0.1 0.0046 16.4 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.6 EPS29672.1 - 0.0046 17.1 1.0 0.065 13.4 0.0 2.9 3 0 0 3 3 3 1 Bacterial SH3 domain C1_2 PF03107.11 EPS29672.1 - 0.074 13.1 6.5 0.13 12.4 4.5 1.4 1 0 0 1 1 1 0 C1 domain YlqD PF11068.3 EPS29672.1 - 0.48 10.4 9.5 1.1 9.2 1.3 3.1 2 1 1 3 3 3 0 YlqD protein DUF2458 PF10454.4 EPS29672.1 - 1.8 8.4 9.8 5.1 6.9 0.7 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2458) DEAD PF00270.24 EPS29674.1 - 6.6e-29 100.5 0.0 1.1e-27 96.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPS29674.1 - 3.4e-21 74.8 0.2 6e-21 74.0 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.1 EPS29674.1 - 0.058 12.9 0.0 4.5 6.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain Fungal_trans PF04082.13 EPS29676.1 - 1.6e-10 40.3 0.2 2.9e-10 39.4 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS29676.1 - 2.9e-07 30.2 7.9 5.6e-07 29.3 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GTP_CH_N PF12471.3 EPS29677.1 - 3.3e-92 307.4 0.0 5.1e-92 306.8 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 EPS29677.1 - 3.3e-17 62.2 0.0 5.1e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II adh_short PF00106.20 EPS29678.1 - 1.2e-18 67.5 0.0 1.8e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPS29678.1 - 7.1e-11 42.3 0.0 8.6e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EPS29678.1 - 2.3e-06 27.7 0.1 4.6e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EPS29678.1 - 7.2e-06 25.7 0.0 1.2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 EPS29678.1 - 0.00063 18.8 0.1 0.001 18.1 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase F420_oxidored PF03807.12 EPS29678.1 - 0.00076 19.8 0.1 0.0014 19.0 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 EPS29678.1 - 0.00098 18.6 0.0 0.021 14.2 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EPS29678.1 - 0.0011 19.0 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.3 EPS29678.1 - 0.0049 16.6 0.1 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 EPS29678.1 - 0.012 14.7 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NAD_binding_2 PF03446.10 EPS29678.1 - 0.058 13.2 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase RmlD_sub_bind PF04321.12 EPS29678.1 - 0.13 11.1 0.0 0.21 10.4 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain ADH_zinc_N PF00107.21 EPS29679.1 - 1e-14 54.2 0.0 1.2e-12 47.5 0.0 2.2 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_N PF08240.7 EPS29679.1 - 2.8e-07 30.2 0.2 2.6e-06 27.1 0.1 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EPS29679.1 - 0.0027 18.6 0.0 0.01 16.7 0.0 1.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase Abhydrolase_3 PF07859.8 EPS29680.1 - 5.3e-16 58.8 0.0 6.5e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EPS29680.1 - 3.6e-08 32.4 0.0 6.3e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EPS29680.1 - 0.00051 19.8 0.0 0.00067 19.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EPS29680.1 - 0.00064 18.9 0.0 0.0027 16.9 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.8 EPS29681.1 - 8.7e-34 116.8 0.0 3e-33 115.0 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EPS29681.1 - 7e-06 26.0 0.1 9.9e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ferric_reduct PF01794.14 EPS29682.1 - 4.8e-17 62.2 11.6 4.8e-17 62.2 8.0 2.2 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EPS29682.1 - 9.1e-16 58.1 0.0 2.2e-15 56.9 0.0 1.7 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EPS29682.1 - 1.9e-12 46.9 0.0 1.3e-11 44.2 0.0 2.2 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EPS29682.1 - 0.14 12.6 0.0 0.41 11.2 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF2014 PF09427.5 EPS29683.1 - 6e-104 346.7 0.9 8.3e-104 346.3 0.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.21 EPS29683.1 - 3.4e-19 68.2 0.4 1e-18 66.7 0.3 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Leu_zip PF15294.1 EPS29683.1 - 0.047 12.7 0.8 0.077 12.0 0.5 1.2 1 0 0 1 1 1 0 Leucine zipper TSC22 PF01166.13 EPS29683.1 - 0.33 10.9 1.8 0.83 9.6 0.4 2.1 2 0 0 2 2 2 0 TSC-22/dip/bun family E1-E2_ATPase PF00122.15 EPS29684.1 - 5.3e-63 212.1 5.6 1.1e-62 211.0 3.9 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EPS29684.1 - 3.3e-31 108.2 2.2 3.3e-31 108.2 1.6 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EPS29684.1 - 2.3e-29 103.3 0.0 1.9e-28 100.3 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EPS29684.1 - 3.2e-17 61.7 0.1 3.2e-17 61.7 0.1 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EPS29684.1 - 3e-14 53.6 0.0 7.2e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPS29684.1 - 2.9e-13 49.5 0.0 6.2e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EPS29684.1 - 3.8e-07 29.9 1.5 6.8e-06 25.8 0.5 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RNase_PH PF01138.16 EPS29685.1 - 0.00063 20.0 0.0 0.00095 19.4 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 NAD_kinase PF01513.16 EPS29687.1 - 3.9e-69 232.5 0.0 5e-69 232.2 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase GAF_2 PF13185.1 EPS29688.1 - 5.2e-09 36.7 0.0 7.1e-09 36.3 0.0 1.3 1 1 0 1 1 1 1 GAF domain GAF PF01590.21 EPS29688.1 - 1.6e-06 28.3 0.0 1.9e-06 28.0 0.0 1.4 1 1 0 1 1 1 1 GAF domain GAF_3 PF13492.1 EPS29688.1 - 3.1e-05 24.0 0.0 4.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 GAF domain AA_permease_2 PF13520.1 EPS29690.1 - 2.3e-54 184.5 47.3 2.8e-54 184.2 32.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPS29690.1 - 2.5e-21 75.5 44.1 3.3e-21 75.1 30.5 1.1 1 0 0 1 1 1 1 Amino acid permease Trp_oprn_chp PF09534.5 EPS29690.1 - 0.0081 15.7 4.9 0.37 10.3 0.3 2.7 1 1 1 2 2 2 2 Tryptophan-associated transmembrane protein (Trp_oprn_chp) adh_short PF00106.20 EPS29691.1 - 2.2e-37 128.5 0.2 4e-37 127.6 0.1 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPS29691.1 - 8e-22 78.1 0.1 9.5e-22 77.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPS29691.1 - 3.1e-15 56.3 0.1 4.9e-15 55.6 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPS29691.1 - 4.8e-07 29.4 0.0 9.2e-07 28.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EPS29691.1 - 1.2e-05 25.0 0.0 2.5e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EPS29691.1 - 2.9e-05 22.9 0.0 3.8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EPS29691.1 - 0.0017 17.3 0.0 0.0023 16.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EPS29691.1 - 0.0022 17.9 0.3 0.0032 17.4 0.2 1.7 1 1 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 EPS29691.1 - 0.0025 17.7 0.0 0.0064 16.4 0.0 1.6 2 0 0 2 2 2 1 TrkA-N domain THF_DHG_CYH_C PF02882.14 EPS29691.1 - 0.0028 16.7 0.1 0.014 14.4 0.1 2.0 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_4 PF07993.7 EPS29691.1 - 0.0056 15.6 0.0 0.011 14.6 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 EPS29691.1 - 0.0079 15.1 0.0 0.011 14.6 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain F420_oxidored PF03807.12 EPS29691.1 - 0.013 15.9 0.1 0.028 14.8 0.0 1.6 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Methyltransf_25 PF13649.1 EPS29691.1 - 0.015 15.6 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EPS29691.1 - 0.017 15.5 0.0 0.035 14.5 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Shikimate_DH PF01488.15 EPS29691.1 - 0.022 14.8 0.1 0.056 13.5 0.1 1.7 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EPS29691.1 - 0.025 14.8 0.0 0.044 14.0 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.11 EPS29691.1 - 0.03 13.7 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AdoHcyase_NAD PF00670.16 EPS29691.1 - 0.032 14.0 0.9 0.071 12.9 0.1 1.9 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_3 PF03447.11 EPS29691.1 - 0.035 14.4 0.1 0.094 13.1 0.0 1.7 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 EPS29691.1 - 0.037 13.7 0.1 0.096 12.4 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Mito_carr PF00153.22 EPS29693.1 - 4.2e-41 138.5 0.8 2.1e-21 75.4 0.0 2.7 2 1 1 3 3 3 2 Mitochondrial carrier protein Anp1 PF03452.9 EPS29694.1 - 6.5e-107 356.6 0.0 8.5e-107 356.3 0.0 1.1 1 0 0 1 1 1 1 Anp1 DUF1049 PF06305.6 EPS29694.1 - 0.061 12.8 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF2615 PF11027.3 EPS29694.1 - 0.11 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) Zip PF02535.17 EPS29695.1 - 5.9e-60 202.9 6.7 1.4e-59 201.6 4.7 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter Nop16 PF09420.5 EPS29696.1 - 4e-59 199.3 10.4 4.8e-59 199.1 7.2 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 Pex24p PF06398.6 EPS29697.1 - 5.7e-87 291.8 0.0 7.4e-87 291.4 0.0 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF639 PF04842.7 EPS29697.1 - 0.072 11.2 0.7 0.11 10.6 0.5 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) Pkinase PF00069.20 EPS29698.1 - 4.5e-58 196.4 0.0 6.4e-58 195.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS29698.1 - 4.8e-19 68.4 0.0 8.2e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPS29698.1 - 0.051 13.2 0.0 0.53 9.9 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EPS29698.1 - 0.29 9.8 0.2 0.43 9.3 0.2 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase COPIIcoated_ERV PF07970.7 EPS29700.1 - 3.1e-32 112.0 0.3 3e-31 108.7 0.2 2.1 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EPS29700.1 - 2e-24 85.3 0.0 4.2e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Filament PF00038.16 EPS29701.1 - 1.9e-09 37.4 25.6 1.9e-09 37.4 17.7 3.6 4 1 0 4 4 4 1 Intermediate filament protein DUF4200 PF13863.1 EPS29701.1 - 0.00089 19.2 14.2 0.00089 19.2 9.8 6.3 5 2 1 6 6 6 2 Domain of unknown function (DUF4200) DUF3166 PF11365.3 EPS29701.1 - 0.013 15.9 3.6 0.013 15.9 2.5 5.2 4 2 0 5 5 5 0 Protein of unknown function (DUF3166) Cep57_CLD PF14073.1 EPS29701.1 - 0.013 15.3 10.4 0.013 15.3 7.2 4.3 4 1 0 4 4 4 0 Centrosome localisation domain of Cep57 Reo_sigmaC PF04582.7 EPS29701.1 - 0.019 14.1 15.0 0.39 9.8 4.9 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein HALZ PF02183.13 EPS29701.1 - 0.11 12.1 0.1 0.11 12.1 0.1 5.4 5 0 0 5 5 5 0 Homeobox associated leucine zipper Peptidase_MA_2 PF13485.1 EPS29702.1 - 0.00015 21.7 0.0 0.00028 20.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily BSP PF04450.7 EPS29702.1 - 0.0021 17.5 0.0 0.0032 16.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase of plants and bacteria PDZ PF00595.19 EPS29702.1 - 0.022 14.8 0.0 0.061 13.4 0.0 1.7 1 0 0 1 1 1 0 PDZ domain (Also known as DHR or GLGF) DUF2771 PF10969.3 EPS29704.1 - 0.059 12.6 0.0 0.084 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2771) DUF3586 PF12131.3 EPS29705.1 - 0.01 15.8 0.9 0.014 15.4 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3586) Asparaginase_II PF06089.7 EPS29706.1 - 7.9e-54 182.5 0.0 8.7e-54 182.3 0.0 1.0 1 0 0 1 1 1 1 L-asparaginase II Maf1 PF09174.5 EPS29707.1 - 2.6e-63 213.0 0.0 3.4e-63 212.7 0.0 1.1 1 0 0 1 1 1 1 Maf1 regulator Clat_adaptor_s PF01217.15 EPS29708.1 - 6e-53 178.3 1.1 7.1e-53 178.1 0.7 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Fungal_trans_2 PF11951.3 EPS29708.1 - 0.099 11.2 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Fungal specific transcription factor domain Sugar_tr PF00083.19 EPS29710.1 - 3.2e-17 62.2 29.2 2.4e-15 56.0 20.2 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS29710.1 - 9.5e-13 47.5 17.9 5.5e-08 31.9 1.0 2.9 3 0 0 3 3 3 2 Major Facilitator Superfamily DUF2333 PF10095.4 EPS29710.1 - 0.099 11.2 0.0 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) PRELI PF04707.9 EPS29711.1 - 3.9e-24 84.9 0.0 1.1e-20 73.8 0.0 2.2 2 0 0 2 2 2 2 PRELI-like family Cecropin PF00272.14 EPS29711.1 - 0.12 11.9 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Cecropin family PA_decarbox PF05870.6 EPS29714.1 - 8.8e-11 41.5 0.0 1e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) DIM PF08194.7 EPS29715.1 - 0.0064 16.4 0.6 0.0064 16.4 0.4 1.9 2 1 0 2 2 2 1 DIM protein Hydrophobin PF01185.13 EPS29715.1 - 0.19 12.1 9.8 2.6 8.5 0.4 2.1 1 1 1 2 2 2 0 Fungal hydrophobin Metallophos PF00149.23 EPS29716.1 - 6e-05 22.5 5.5 8.3e-05 22.0 0.2 2.7 3 0 0 3 3 3 2 Calcineurin-like phosphoesterase MARVEL PF01284.18 EPS29717.1 - 3.1e-27 95.1 15.6 3.6e-27 94.9 10.8 1.0 1 0 0 1 1 1 1 Membrane-associating domain SUR7 PF06687.7 EPS29717.1 - 0.96 8.9 12.7 2.3 7.7 8.8 1.7 1 1 0 1 1 1 0 SUR7/PalI family Pex24p PF06398.6 EPS29718.1 - 1.3e-06 27.5 5.2 2.1e-06 26.8 3.6 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF4476 PF14771.1 EPS29718.1 - 0.00089 19.2 0.1 0.0018 18.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4476) Mis14 PF08641.7 EPS29719.1 - 3.4e-29 101.6 0.6 3.4e-29 101.6 0.4 2.7 2 1 1 3 3 3 1 Kinetochore protein Mis14 like FUSC PF04632.7 EPS29719.1 - 0.53 8.6 6.6 0.74 8.1 4.6 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Hid1 PF12722.2 EPS29719.1 - 3.3 5.2 4.6 4 4.9 3.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CRAL_TRIO PF00650.15 EPS29720.1 - 1.1e-35 122.4 0.0 1.8e-35 121.8 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EPS29720.1 - 2.7e-10 40.1 0.3 9.6e-10 38.4 0.2 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EPS29720.1 - 5.6e-06 26.3 0.0 2.1e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain RasGAP PF00616.14 EPS29721.1 - 7.2e-55 185.7 0.0 7.2e-55 185.7 0.0 2.2 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 EPS29721.1 - 9.3e-32 109.6 3.2 9.3e-32 109.6 2.2 2.5 2 0 0 2 2 2 1 RasGAP C-terminus DUF2363 PF10155.4 EPS29721.1 - 0.55 10.1 4.1 47 3.9 0.0 4.4 3 2 1 4 4 4 0 Uncharacterized conserved protein (DUF2363) DUF972 PF06156.8 EPS29721.1 - 3.4 8.0 11.5 4.3 7.7 1.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF972) VIT1 PF01988.14 EPS29724.1 - 0.4 10.1 4.8 0.6 9.5 3.3 1.3 1 0 0 1 1 1 0 VIT family Acetyltransf_1 PF00583.19 EPS29725.1 - 1.9e-18 66.2 0.0 3e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EPS29725.1 - 4.3e-12 46.1 0.0 6.7e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPS29725.1 - 1.3e-11 44.0 0.0 2.4e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EPS29725.1 - 1.9e-11 43.9 0.0 3.2e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EPS29725.1 - 6.3e-09 36.1 0.0 9.3e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EPS29725.1 - 4e-07 30.0 0.0 5.6e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPS29725.1 - 4.1e-06 26.6 0.1 9.8e-06 25.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EPS29725.1 - 0.00047 20.1 0.0 0.00062 19.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 EPS29725.1 - 0.0023 17.5 0.1 0.0032 17.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EPS29725.1 - 0.0038 17.0 0.0 0.0076 16.1 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase GNAT_acetyltran PF12746.2 EPS29725.1 - 0.018 13.8 0.3 0.042 12.6 0.0 1.6 2 0 0 2 2 2 0 GNAT acetyltransferase LCAT PF02450.10 EPS29726.1 - 9.8e-96 321.0 0.0 1.2e-95 320.7 0.0 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.13 EPS29726.1 - 0.007 15.6 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 2) DUF900 PF05990.7 EPS29726.1 - 0.014 14.7 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.2 EPS29726.1 - 0.08 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family PAP2 PF01569.16 EPS29727.1 - 1.8e-14 53.5 5.4 1.8e-14 53.5 3.8 2.0 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 EPS29727.1 - 1.5e-06 27.8 6.2 1.5e-06 27.8 4.3 1.9 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.1 EPS29727.1 - 1.1 9.6 8.1 0.59 10.4 3.0 2.5 2 0 0 2 2 2 0 PAP2 superfamily C-terminal Fungal_trans PF04082.13 EPS29728.1 - 2e-11 43.2 0.3 7.4e-11 41.4 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS29728.1 - 4.1e-07 29.7 10.5 8.6e-07 28.7 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amino_oxidase PF01593.19 EPS29729.1 - 6.5e-49 167.2 0.8 1.9e-48 165.6 0.6 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EPS29729.1 - 6.7e-13 48.4 0.4 5.8e-12 45.4 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EPS29729.1 - 1.3e-08 34.2 1.2 5.9e-07 28.7 0.3 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EPS29729.1 - 1.9e-06 27.1 0.1 3.2e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EPS29729.1 - 0.00011 21.2 0.2 0.00018 20.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EPS29729.1 - 0.00012 21.3 0.0 0.0017 17.5 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EPS29729.1 - 0.00027 20.1 0.1 0.0036 16.4 0.2 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EPS29729.1 - 0.00061 18.3 0.0 0.0012 17.4 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.22 EPS29729.1 - 0.0013 19.0 0.1 0.0032 17.8 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPS29729.1 - 0.0014 18.6 0.1 0.044 13.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EPS29729.1 - 0.0032 16.4 0.0 0.0064 15.4 0.0 1.6 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EPS29729.1 - 0.004 17.0 0.1 0.0082 16.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EPS29729.1 - 0.0065 15.3 0.0 0.0096 14.8 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A GDI PF00996.13 EPS29729.1 - 0.19 9.9 0.0 0.28 9.4 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor VIT1 PF01988.14 EPS29730.1 - 4.9e-58 196.1 3.6 6.5e-58 195.7 2.5 1.2 1 0 0 1 1 1 1 VIT family Abhydrolase_9_N PF15420.1 EPS29730.1 - 0.058 13.1 0.5 0.094 12.4 0.4 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family N-terminus FIST PF08495.5 EPS29730.1 - 0.13 11.3 0.0 0.13 11.3 0.0 1.8 2 0 0 2 2 2 0 FIST N domain Phosphoesterase PF04185.9 EPS29731.1 - 1.9e-59 201.7 6.7 1.6e-58 198.7 4.7 2.1 1 1 0 1 1 1 1 Phosphoesterase family GPI-anchored PF10342.4 EPS29732.1 - 1.8e-19 69.9 6.2 1.8e-19 69.9 4.3 2.6 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family fn3 PF00041.16 EPS29732.1 - 0.00063 19.8 0.7 0.0021 18.1 0.5 1.9 1 0 0 1 1 1 1 Fibronectin type III domain Activator_LAG-3 PF11498.3 EPS29732.1 - 0.32 9.6 4.7 0.45 9.2 3.2 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF572 PF04502.8 EPS29732.1 - 0.94 8.6 6.1 1.1 8.3 4.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4614 PF15391.1 EPS29732.1 - 1.3 8.7 17.0 0.52 10.0 9.7 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4614) TFIIA PF03153.8 EPS29732.1 - 2.4 7.9 9.2 3 7.6 6.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rifin_STEVOR PF02009.11 EPS29732.1 - 4.3 6.9 5.3 5 6.6 3.7 1.1 1 0 0 1 1 1 0 Rifin/stevor family Alpha-amylase PF00128.19 EPS29733.1 - 4.1e-25 88.8 0.0 9.9e-25 87.5 0.0 1.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 EPS29733.1 - 3.7e-06 25.0 0.1 0.012 13.4 0.0 2.9 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 Alpha-amylase PF00128.19 EPS29734.1 - 3.2e-55 187.7 3.2 4.1e-55 187.3 2.2 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EPS29734.1 - 1.3e-31 108.4 0.2 2.6e-31 107.5 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) DUF187 PF02638.10 EPS29734.1 - 0.02 13.7 0.3 0.032 13.1 0.2 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase like GH101 Glyco_transf_5 PF08323.6 EPS29735.1 - 1.7e-16 60.4 0.1 3.9e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Alpha-amylase PF00128.19 EPS29735.1 - 2.6e-14 53.3 1.6 4.3e-13 49.3 1.6 2.4 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Glycos_transf_1 PF00534.15 EPS29735.1 - 2e-06 27.3 0.0 3.9e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EPS29735.1 - 2.5e-06 27.7 0.0 5.6e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DC_STAMP PF07782.8 EPS29736.1 - 0.0069 16.0 0.0 0.0076 15.8 0.0 1.1 1 0 0 1 1 1 1 DC-STAMP-like protein DUF4330 PF14221.1 EPS29736.1 - 0.0094 15.8 0.1 0.011 15.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4330) Consortin_C PF15281.1 EPS29736.1 - 0.01 15.2 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 0 Consortin C-terminus Baculo_E56 PF04639.7 EPS29736.1 - 0.017 13.7 0.7 0.024 13.2 0.5 1.2 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope SpoIIIAH PF12685.2 EPS29736.1 - 0.02 14.3 0.0 0.024 14.1 0.0 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein Anoctamin PF04547.7 EPS29736.1 - 0.032 12.8 0.0 0.036 12.7 0.0 1.0 1 0 0 1 1 1 0 Calcium-activated chloride channel AsnA PF03590.10 EPS29736.1 - 0.044 13.2 0.1 0.052 12.9 0.1 1.0 1 0 0 1 1 1 0 Aspartate-ammonia ligase DUF1183 PF06682.7 EPS29736.1 - 0.044 13.3 0.0 0.044 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) DUF1628 PF07790.6 EPS29736.1 - 0.052 14.3 0.1 0.068 13.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1628) MacB_PCD PF12704.2 EPS29736.1 - 0.056 13.0 0.0 0.062 12.8 0.0 1.1 1 0 0 1 1 1 0 MacB-like periplasmic core domain DUF2500 PF10694.4 EPS29736.1 - 0.066 13.2 0.2 0.08 12.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2500) Brr6_like_C_C PF10104.4 EPS29736.1 - 0.11 12.0 0.2 0.13 11.7 0.2 1.2 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain HemY_N PF07219.8 EPS29736.1 - 0.11 12.1 0.1 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 HemY protein N-terminus Chordopox_A13L PF05961.6 EPS29736.1 - 0.13 12.2 2.6 0.2 11.6 1.8 1.5 1 1 0 1 1 1 0 Chordopoxvirus A13L protein DUF1035 PF06281.7 EPS29736.1 - 0.48 10.2 2.7 0.83 9.4 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1035) DUF2874 PF11396.3 EPS29737.1 - 0.11 12.5 2.7 10 6.1 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2874) MotA_ExbB PF01618.11 EPS29737.1 - 1.2 8.7 5.9 2.2 7.9 0.3 2.9 3 0 0 3 3 3 0 MotA/TolQ/ExbB proton channel family cNMP_binding PF00027.24 EPS29738.1 - 5.7e-41 138.2 0.0 2.6e-21 75.2 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain 2OG-FeII_Oxy_3 PF13640.1 EPS29739.1 - 1.8e-11 44.3 0.0 2.9e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EPS29739.1 - 3.2e-08 33.0 0.0 5.7e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EPS29739.1 - 0.0015 18.7 0.0 0.0027 17.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fork_head PF00250.13 EPS29740.1 - 6.1e-17 61.4 0.0 1.2e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EPS29740.1 - 9e-06 25.7 0.0 1.7e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 FHA domain Cyclin PF08613.6 EPS29742.1 - 1.2e-17 64.7 0.0 2.1e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EPS29742.1 - 0.0062 16.0 0.0 0.0062 16.0 0.0 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Zip PF02535.17 EPS29742.1 - 0.31 10.0 5.8 0.49 9.3 4.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter BAF1_ABF1 PF04684.8 EPS29742.1 - 0.31 9.8 13.1 0.46 9.2 9.1 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor His_Phos_1 PF00300.17 EPS29743.1 - 1.3e-33 116.3 1.2 2e-33 115.7 0.0 2.0 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 EPS29743.1 - 1.8e-06 27.5 0.9 3.1e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) GCP5-Mod21 PF14609.1 EPS29743.1 - 0.15 10.1 1.9 0.21 9.6 1.3 1.1 1 0 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 Dor1 PF04124.7 EPS29744.1 - 3.3e-56 190.1 4.3 1.6e-44 151.7 1.8 2.4 1 1 0 2 2 2 2 Dor1-like family Vps51 PF08700.6 EPS29744.1 - 0.00015 21.5 0.8 0.0005 19.8 0.5 1.9 1 0 0 1 1 1 1 Vps51/Vps67 Sec5 PF15469.1 EPS29744.1 - 0.00049 19.8 0.0 0.002 17.8 0.0 2.0 1 1 0 1 1 1 1 Exocyst complex component Sec5 ApoLp-III PF07464.6 EPS29744.1 - 0.014 15.3 1.0 0.045 13.7 0.2 2.1 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) GAS PF13851.1 EPS29744.1 - 0.022 13.9 1.9 0.031 13.4 0.2 1.9 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 EPS29744.1 - 0.66 9.5 8.0 0.22 11.1 3.0 2.0 2 0 0 2 2 2 0 IncA protein EAF PF09816.4 EPS29745.1 - 3.5e-23 81.6 0.1 5.8e-23 80.9 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Cyclin_N PF00134.18 EPS29746.1 - 2.1e-15 56.4 1.9 5e-15 55.1 0.5 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EPS29746.1 - 1.5e-05 24.8 0.0 0.00023 21.0 0.0 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain TFIIB PF00382.14 EPS29746.1 - 0.19 11.5 4.1 1.3 8.8 0.7 2.6 2 1 0 2 2 2 0 Transcription factor TFIIB repeat SOG2 PF10428.4 EPS29746.1 - 0.7 8.4 11.1 22 3.5 0.0 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein DUF605 PF04652.11 EPS29746.1 - 9.4 5.5 18.9 13 5.0 13.1 1.2 1 0 0 1 1 1 0 Vta1 like Pkinase PF00069.20 EPS29747.1 - 4.4e-65 219.4 0.0 5.5e-65 219.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS29747.1 - 2.8e-28 98.7 0.0 4.2e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPS29747.1 - 0.046 12.6 0.1 0.32 9.9 0.0 1.9 1 1 0 2 2 2 0 Kinase-like Barttin PF15462.1 EPS29747.1 - 4.3 6.9 7.4 0.44 10.1 1.6 1.9 2 1 0 2 2 2 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) FolB PF02152.13 EPS29748.1 - 2.2e-21 76.1 0.0 4.9e-17 62.1 0.0 2.2 2 0 0 2 2 2 2 Dihydroneopterin aldolase RRM_1 PF00076.17 EPS29749.1 - 1.1e-24 85.8 0.1 1.6e-13 50.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS29749.1 - 5.3e-18 64.7 0.0 7.3e-09 35.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS29749.1 - 1.9e-13 50.0 0.0 6.2e-07 29.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EPS29749.1 - 0.0063 16.3 0.1 0.32 10.8 0.0 2.1 2 0 0 2 2 2 1 RNA binding motif ETF_QO PF05187.8 EPS29750.1 - 8.9e-46 154.4 0.0 1.4e-45 153.7 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 EPS29750.1 - 6.1e-09 35.2 0.1 0.00037 19.5 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPS29750.1 - 1.3e-06 27.5 0.3 0.0011 17.9 0.5 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EPS29750.1 - 1.5e-06 28.1 0.0 4.3e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EPS29750.1 - 2.7e-06 26.7 0.0 4.4e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EPS29750.1 - 3.4e-05 24.1 0.1 0.16 12.3 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPS29750.1 - 0.00014 21.8 0.0 0.00021 21.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EPS29750.1 - 0.00018 20.6 0.0 0.0003 19.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EPS29750.1 - 0.00039 19.0 0.5 0.00059 18.4 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 EPS29750.1 - 0.0007 19.7 0.0 0.0011 19.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPS29750.1 - 0.0013 17.8 0.0 0.0038 16.3 0.1 1.6 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 EPS29750.1 - 0.0017 18.1 0.2 0.0054 16.5 0.1 2.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding Fer4_7 PF12838.2 EPS29750.1 - 0.0057 17.0 1.1 0.015 15.6 0.8 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Trp_halogenase PF04820.9 EPS29750.1 - 0.0069 15.0 0.1 0.2 10.2 0.1 2.1 1 1 1 2 2 2 1 Tryptophan halogenase Lycopene_cycl PF05834.7 EPS29750.1 - 0.036 12.9 0.4 0.053 12.4 0.3 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 EPS29750.1 - 0.11 11.3 0.1 0.17 10.7 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A TBP PF00352.16 EPS29752.1 - 8.6e-70 230.1 0.1 9e-35 117.9 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EPS29752.1 - 7.6e-05 22.6 0.0 0.3 11.1 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DAO PF01266.19 EPS29753.1 - 1.7e-48 165.3 0.8 2.1e-48 165.0 0.6 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EPS29753.1 - 5e-06 26.5 0.1 0.022 14.6 0.0 2.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPS29753.1 - 7.1e-06 25.8 0.3 0.058 13.1 0.1 2.6 2 1 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EPS29753.1 - 5.5e-05 23.1 0.3 0.00017 21.5 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EPS29753.1 - 6.8e-05 21.6 0.1 0.0037 15.9 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase GIDA PF01134.17 EPS29753.1 - 0.00024 20.1 0.0 0.00069 18.5 0.0 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EPS29753.1 - 0.001 18.0 1.1 0.014 14.2 0.8 2.1 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EPS29753.1 - 0.0025 16.8 0.1 0.017 14.0 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.22 EPS29753.1 - 0.0047 17.2 0.0 0.01 16.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EPS29753.1 - 0.0048 15.9 0.0 0.65 8.9 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EPS29753.1 - 0.0054 16.8 0.1 0.13 12.2 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EPS29753.1 - 0.07 13.1 0.0 0.2 11.6 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain K_oxygenase PF13434.1 EPS29753.1 - 0.076 11.9 0.0 0.57 9.0 0.0 2.0 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Methyltransf_23 PF13489.1 EPS29754.1 - 6.4e-26 91.0 0.0 9.4e-26 90.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPS29754.1 - 4.8e-07 30.1 0.0 1.1e-06 29.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS29754.1 - 0.00011 22.7 0.1 0.00026 21.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPS29754.1 - 0.00045 20.5 0.0 0.00094 19.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPS29754.1 - 0.00064 20.1 0.0 0.022 15.2 0.0 2.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPS29754.1 - 0.0012 18.8 0.0 0.0022 18.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPS29754.1 - 0.0014 18.2 0.0 0.0041 16.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain DUF3611 PF12263.3 EPS29754.1 - 0.18 11.1 0.8 0.47 9.8 0.0 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF3611) Fungal_trans PF04082.13 EPS29756.1 - 2.8e-22 78.8 0.2 4.8e-22 78.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS29756.1 - 2.1e-07 30.7 10.3 3.6e-07 29.9 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Phage_gp53 PF11246.3 EPS29756.1 - 0.049 13.0 0.4 0.077 12.4 0.3 1.3 1 0 0 1 1 1 0 Base plate wedge protein 53 DUF3864 PF12980.2 EPS29757.1 - 0.00062 19.9 0.0 0.0018 18.4 0.0 1.7 1 0 0 1 1 1 1 Domain of Unknown Function with PDB structure (DUF3864) HTH_IclR PF09339.5 EPS29757.1 - 0.022 14.3 0.3 2.8 7.6 0.0 3.5 3 0 0 3 3 3 0 IclR helix-turn-helix domain DUF3927 PF13064.1 EPS29757.1 - 0.19 11.2 0.1 0.39 10.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3927) Ndc80_HEC PF03801.8 EPS29759.1 - 4.3e-63 211.5 0.0 9.6e-63 210.3 0.0 1.6 1 0 0 1 1 1 1 HEC/Ndc80p family IncA PF04156.9 EPS29759.1 - 0.0019 17.8 17.5 0.0019 17.8 12.1 3.8 2 2 0 3 3 3 1 IncA protein HSBP1 PF06825.7 EPS29759.1 - 0.0022 17.5 6.1 0.052 13.1 0.1 4.3 4 1 0 4 4 4 1 Heat shock factor binding protein 1 DUF1409 PF07197.7 EPS29759.1 - 0.018 15.0 10.4 0.75 9.9 0.9 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1409) NPV_P10 PF05531.7 EPS29759.1 - 0.07 13.3 15.4 0.56 10.4 0.6 4.3 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Adenylsucc_synt PF00709.16 EPS29759.1 - 0.082 11.5 10.3 1.7 7.1 0.1 2.4 2 0 0 2 2 2 0 Adenylosuccinate synthetase Filament PF00038.16 EPS29759.1 - 0.16 11.4 49.0 0.28 10.6 15.7 2.8 2 1 0 2 2 2 0 Intermediate filament protein TMCO5 PF14992.1 EPS29759.1 - 2.1 7.4 44.6 0.11 11.6 5.8 3.2 2 1 0 2 2 2 0 TMCO5 family Tropomyosin_1 PF12718.2 EPS29759.1 - 5.7 6.7 54.4 0.78 9.5 11.9 4.3 2 2 2 4 4 4 0 Tropomyosin like APG6 PF04111.7 EPS29759.1 - 8.6 5.2 47.3 1.4 7.9 9.5 3.3 2 1 1 3 3 3 0 Autophagy protein Apg6 Pex14_N PF04695.8 EPS29760.1 - 6.5e-43 146.0 0.0 6.5e-43 146.0 0.0 3.3 2 1 1 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Baculo_PEP_C PF04513.7 EPS29760.1 - 0.0032 17.3 0.5 0.0096 15.7 0.4 1.8 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Cytochrom_B562 PF07361.6 EPS29760.1 - 0.021 15.1 1.2 0.054 13.9 0.8 1.7 1 0 0 1 1 1 0 Cytochrome b562 IncA PF04156.9 EPS29760.1 - 0.027 14.0 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 IncA protein DUF3584 PF12128.3 EPS29760.1 - 0.033 11.5 4.3 0.044 11.1 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) BID PF06393.6 EPS29760.1 - 0.034 13.5 0.1 0.065 12.5 0.1 1.4 1 0 0 1 1 1 0 BH3 interacting domain (BID) DUF3829 PF12889.2 EPS29760.1 - 0.086 12.0 1.0 0.13 11.4 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) DUF848 PF05852.6 EPS29760.1 - 0.18 11.6 2.7 0.34 10.7 1.8 1.4 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) EamA PF00892.15 EPS29760.1 - 0.18 11.8 0.0 0.29 11.1 0.0 1.2 1 0 0 1 1 1 0 EamA-like transporter family zf-C4H2 PF10146.4 EPS29760.1 - 0.32 10.9 9.4 0.08 12.9 3.2 2.4 2 1 0 2 2 2 0 Zinc finger-containing protein GAS PF13851.1 EPS29760.1 - 0.58 9.3 3.0 1.1 8.4 2.1 1.5 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Acetyltransf_3 PF13302.1 EPS29762.1 - 2.7e-15 56.7 0.0 3.8e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EPS29762.1 - 7.9e-08 32.3 0.0 9.6e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPS29762.1 - 3.5e-06 26.9 0.0 5.1e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EPS29762.1 - 0.034 14.0 0.0 0.062 13.1 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain PrpF PF04303.8 EPS29763.1 - 1.1e-105 353.4 1.0 1.3e-105 353.2 0.7 1.0 1 0 0 1 1 1 1 PrpF protein TTL PF03133.10 EPS29764.1 - 5.2e-56 189.7 0.0 7.8e-56 189.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.12 EPS29764.1 - 7.2e-44 149.4 0.0 1.1e-43 148.8 0.0 1.3 1 0 0 1 1 1 1 Survival protein SurE ATP-grasp_4 PF13535.1 EPS29764.1 - 0.00013 21.7 0.5 0.0036 17.0 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_YheCD PF14398.1 EPS29764.1 - 0.0016 17.2 0.0 0.026 13.3 0.0 2.1 2 0 0 2 2 2 1 YheC/D like ATP-grasp Glyco_trans_4_4 PF13579.1 EPS29764.1 - 0.011 15.8 0.0 0.027 14.5 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Seipin PF06775.9 EPS29765.1 - 2.4e-63 213.2 0.0 3.9e-63 212.5 0.0 1.3 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Not1 PF04054.10 EPS29766.1 - 1.3e-137 458.7 1.5 2.5e-137 457.8 1.0 1.4 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EPS29766.1 - 2.3e-51 173.3 1.5 5.6e-51 172.1 1.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) Surp PF01805.15 EPS29769.1 - 1.1e-18 66.6 0.0 1.9e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Surp module TMA7 PF09072.5 EPS29770.1 - 2.4e-24 85.5 19.0 2.6e-24 85.4 13.2 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 NTF2 PF02136.15 EPS29771.1 - 3.1e-32 111.4 0.2 3.5e-32 111.2 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.1 EPS29771.1 - 0.058 13.6 0.0 0.07 13.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) PQ-loop PF04193.9 EPS29772.1 - 1.7e-17 62.7 22.8 4.1e-10 39.0 1.3 3.4 3 1 1 4 4 4 2 PQ loop repeat DUF485 PF04341.7 EPS29772.1 - 1.8 8.3 7.3 3.2 7.5 0.3 3.2 2 1 2 4 4 4 0 Protein of unknown function, DUF485 Ish1 PF10281.4 EPS29773.1 - 2.2e-81 267.4 21.5 3.8e-14 52.4 0.0 7.6 7 0 0 7 7 7 7 Putative stress-responsive nuclear envelope protein HeH PF12949.2 EPS29773.1 - 5.7e-13 48.1 0.2 0.01 15.3 0.1 6.1 7 0 0 7 7 7 4 HeH/LEM domain SAP PF02037.22 EPS29773.1 - 4.6e-11 41.9 0.0 0.49 9.9 0.0 6.6 7 2 0 7 7 7 3 SAP domain APC2 PF08672.6 EPS29773.1 - 0.00027 21.1 5.9 55 4.1 0.0 6.3 7 0 0 7 7 7 0 Anaphase promoting complex (APC) subunit 2 Slx4 PF09494.5 EPS29773.1 - 0.0019 17.8 7.6 15 5.4 0.0 5.8 6 0 0 6 6 6 0 Slx4 endonuclease Phasin PF05597.6 EPS29773.1 - 0.0057 16.4 10.5 1.3 8.7 0.1 4.5 4 0 0 4 4 4 2 Poly(hydroxyalcanoate) granule associated protein (phasin) Amidase02_C PF12123.3 EPS29773.1 - 0.0063 16.1 0.1 0.71 9.5 0.2 3.4 3 0 0 3 3 3 1 N-acetylmuramoyl-l-alanine amidase SAM_2 PF07647.12 EPS29773.1 - 0.039 13.7 3.6 12 5.8 0.2 4.7 5 0 0 5 5 5 0 SAM domain (Sterile alpha motif) BCDHK_Adom3 PF10436.4 EPS29773.1 - 0.041 13.3 0.0 2 7.8 0.0 2.9 3 0 0 3 3 3 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase DUF1470 PF07336.6 EPS29773.1 - 2.2 8.6 18.6 8.3 6.7 1.4 5.6 4 1 3 7 7 7 0 Protein of unknown function (DUF1470) DUF3622 PF12286.3 EPS29773.1 - 8 6.8 22.6 14 6.0 0.0 6.7 7 0 0 7 7 7 0 Protein of unknown function (DUF3622) Cyt-b5 PF00173.23 EPS29774.1 - 1.2e-14 53.9 0.0 1.8e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4519 PF15012.1 EPS29774.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) DivIC PF04977.10 EPS29775.1 - 3.9 7.0 4.6 5.9 6.4 0.4 2.2 1 1 1 2 2 2 0 Septum formation initiator Pkinase PF00069.20 EPS29776.1 - 1.5e-52 178.3 0.0 2.2e-52 177.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS29776.1 - 6.1e-25 87.7 0.0 1.3e-24 86.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EPS29776.1 - 0.022 13.5 0.1 0.036 12.8 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 EPS29781.1 - 6.9e-60 202.3 0.0 9e-60 202.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS29781.1 - 8.9e-33 113.4 0.0 1.1e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPS29781.1 - 0.001 18.1 0.0 0.0029 16.6 0.0 1.5 1 1 0 2 2 2 1 Kinase-like APH PF01636.18 EPS29781.1 - 0.003 17.3 0.0 0.021 14.5 0.0 2.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EPS29781.1 - 0.043 12.8 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Apc4_WD40 PF12894.2 EPS29781.1 - 0.14 11.7 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain YrbL-PhoP_reg PF10707.4 EPS29781.1 - 0.16 11.2 0.1 0.32 10.2 0.0 1.4 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL adh_short PF00106.20 EPS29782.1 - 1.1e-32 113.2 4.0 1.5e-32 112.8 2.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPS29782.1 - 2.4e-27 96.2 0.2 4.5e-27 95.3 0.2 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPS29782.1 - 1.1e-17 64.2 1.0 1.4e-17 63.9 0.7 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EPS29782.1 - 0.0018 17.9 1.2 0.0029 17.2 0.9 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_26 PF13659.1 EPS29782.1 - 0.01 15.8 0.1 0.016 15.2 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain Epimerase PF01370.16 EPS29782.1 - 0.027 13.9 0.3 0.04 13.3 0.2 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family AdoHcyase_NAD PF00670.16 EPS29782.1 - 0.029 14.1 3.0 0.048 13.5 1.7 1.5 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Polysacc_synt_2 PF02719.10 EPS29782.1 - 0.034 13.0 0.0 0.05 12.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF4410 PF14366.1 EPS29782.1 - 0.047 13.4 0.6 0.08 12.6 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4410) THF_DHG_CYH_C PF02882.14 EPS29782.1 - 0.057 12.4 0.2 0.11 11.5 0.2 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.14 EPS29782.1 - 0.07 12.2 0.1 0.11 11.6 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EPS29782.1 - 0.084 12.2 0.2 0.13 11.6 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Zn_clus PF00172.13 EPS29783.1 - 2.2e-07 30.6 8.1 2.2e-07 30.6 5.6 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HlyIII PF03006.15 EPS29784.1 - 8.8e-62 208.4 8.3 1.1e-61 208.1 5.8 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF4401 PF14351.1 EPS29784.1 - 0.0077 15.2 0.7 0.0077 15.2 0.5 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4401) Bax1-I PF01027.15 EPS29784.1 - 0.17 11.4 9.7 0.026 14.1 1.8 2.3 1 1 1 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 DUF998 PF06197.8 EPS29784.1 - 1.5 8.1 13.1 0.2 10.9 4.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF998) SAC3_GANP PF03399.11 EPS29785.1 - 2e-07 30.7 0.1 3.1e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EPS29785.1 - 0.0065 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_19 PF14559.1 EPS29786.1 - 7.9e-09 35.7 4.8 0.00035 20.8 0.2 3.0 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 EPS29786.1 - 1.4e-05 24.6 0.6 0.0022 17.6 0.1 2.9 3 0 0 3 3 3 1 TPR repeat TPR_12 PF13424.1 EPS29786.1 - 2.7e-05 23.9 3.5 0.0044 16.9 0.2 3.3 2 2 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EPS29786.1 - 0.0012 18.5 0.5 4.2 7.5 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EPS29786.1 - 0.0014 19.1 6.8 4.5 8.1 0.0 4.1 1 1 3 4 4 4 1 Tetratricopeptide repeat Coatomer_E PF04733.9 EPS29786.1 - 0.004 16.3 0.4 0.0064 15.7 0.3 1.3 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_21 PF09976.4 EPS29786.1 - 0.0065 16.4 2.9 0.084 12.8 0.4 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EPS29786.1 - 0.014 16.0 8.4 0.096 13.3 1.1 3.7 1 1 3 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 EPS29786.1 - 0.019 15.3 7.7 2.9 8.5 0.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Apc3 PF12895.2 EPS29786.1 - 0.019 15.1 0.4 0.68 10.1 0.2 2.8 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EPS29786.1 - 0.019 15.3 1.4 46 4.7 0.0 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat Nup84_Nup100 PF04121.8 EPS29786.1 - 0.03 12.0 0.1 0.043 11.5 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore protein 84 / 107 TPR_1 PF00515.23 EPS29786.1 - 0.092 12.3 1.4 5.6 6.7 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.5 EPS29786.1 - 0.45 9.9 3.1 7.8 5.9 0.2 2.3 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) Glycos_transf_2 PF00535.21 EPS29787.1 - 1.9e-33 115.5 0.0 2.3e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EPS29787.1 - 1.5e-12 47.8 0.0 2.1e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EPS29787.1 - 3.9e-10 39.2 0.0 8.2e-10 38.2 0.0 1.5 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EPS29787.1 - 5.7e-05 22.4 0.0 8.7e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.1 EPS29787.1 - 0.0041 16.8 0.0 0.0054 16.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_4 PF13704.1 EPS29787.1 - 0.079 13.2 0.0 0.18 12.1 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase family 2 DUF1749 PF08538.5 EPS29788.1 - 1.1e-100 336.5 0.0 1.2e-100 336.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 EPS29788.1 - 0.0013 18.6 0.0 0.0027 17.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPS29788.1 - 0.002 17.8 0.0 0.0039 16.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 EPS29788.1 - 0.013 14.9 0.0 0.4 10.0 0.0 2.2 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2305) WD40 PF00400.27 EPS29789.1 - 5.1e-05 22.9 10.4 0.23 11.4 0.1 4.9 4 0 0 4 4 4 3 WD domain, G-beta repeat Nop14 PF04147.7 EPS29789.1 - 6.4 4.5 20.9 8.8 4.1 14.5 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EPS29789.1 - 6.9 5.0 19.4 9.9 4.5 13.4 1.2 1 0 0 1 1 1 0 Daxx Family TMP_2 PF06791.8 EPS29790.1 - 0.091 12.3 0.1 0.099 12.2 0.1 1.0 1 0 0 1 1 1 0 Prophage tail length tape measure protein FCH PF00611.18 EPS29791.1 - 2.5e-19 69.2 1.7 7.9e-19 67.6 0.0 2.6 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 EPS29791.1 - 3.5e-12 45.4 0.0 7.4e-12 44.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EPS29791.1 - 1.2e-10 40.6 0.0 2.4e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EPS29791.1 - 5e-10 38.8 0.0 1e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Rapsyn_N PF10579.4 EPS29791.1 - 0.045 13.5 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 Rapsyn N-terminal myristoylation and linker region DASH_Duo1 PF08651.5 EPS29792.1 - 1.9e-30 104.2 2.7 1.9e-30 104.2 1.9 1.8 2 0 0 2 2 2 1 DASH complex subunit Duo1 Tic20 PF09685.5 EPS29792.1 - 2.1e-07 30.8 3.9 3.5e-07 30.1 2.7 1.2 1 0 0 1 1 1 1 Tic20-like protein Rft-1 PF04506.8 EPS29792.1 - 0.16 10.2 2.0 0.22 9.8 1.4 1.1 1 0 0 1 1 1 0 Rft protein DUF745 PF05335.8 EPS29792.1 - 0.69 9.4 8.2 1.1 8.7 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Tox-GHH PF15636.1 EPS29792.1 - 6.9 6.3 11.2 0.99 9.0 3.1 2.5 3 0 0 3 3 3 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin zf-primase PF09329.6 EPS29794.1 - 1.7e-18 65.9 1.6 2.5e-18 65.3 0.6 1.7 2 0 0 2 2 2 1 Primase zinc finger RNase_H2-Ydr279 PF09468.5 EPS29795.1 - 3.3e-91 305.6 0.1 4.1e-91 305.3 0.1 1.0 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) GalKase_gal_bdg PF10509.4 EPS29796.1 - 1.4e-20 72.2 0.0 2.6e-20 71.4 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 EPS29796.1 - 1.8e-15 56.7 0.4 1.1e-14 54.1 0.6 2.1 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EPS29796.1 - 3.6e-13 49.5 0.0 8.1e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal Sigma70_r3 PF04539.11 EPS29796.1 - 0.066 13.1 0.5 0.7 9.8 0.2 2.4 2 0 0 2 2 2 0 Sigma-70 region 3 RPA_C PF08784.6 EPS29796.1 - 0.1 12.9 0.0 0.3 11.5 0.0 1.7 1 0 0 1 1 1 0 Replication protein A C terminal PP2C_C PF07830.8 EPS29796.1 - 0.21 11.7 0.7 10 6.2 0.0 2.7 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain TPP_enzyme_N PF02776.13 EPS29798.1 - 7.1e-58 194.8 0.1 1.3e-55 187.5 0.0 2.9 3 0 0 3 3 3 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EPS29798.1 - 3.1e-48 163.2 0.1 6.8e-47 158.8 0.0 2.7 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EPS29798.1 - 1.9e-38 131.3 0.1 4.7e-38 130.0 0.1 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.14 EPS29798.1 - 0.028 13.9 0.0 0.058 12.8 0.0 1.5 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Vps35 PF03635.12 EPS29799.1 - 0 1045.2 1.7 0 1045.0 1.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 UPF0561 PF10573.4 EPS29799.1 - 0.12 12.2 1.5 0.31 10.8 1.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 2CSK_N PF08521.5 EPS29800.1 - 0.013 14.9 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Two-component sensor kinase N-terminal Dsh_C PF12316.3 EPS29800.1 - 0.22 11.6 4.8 0.29 11.2 3.4 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal NST1 PF13945.1 EPS29801.1 - 4.2e-67 225.9 1.8 4.2e-67 225.9 1.2 4.6 2 2 2 4 4 4 1 Salt tolerance down-regulator Ras PF00071.17 EPS29803.1 - 6.6e-48 162.1 0.0 7.7e-48 161.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPS29803.1 - 7.9e-16 58.6 0.0 1.2e-15 58.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPS29803.1 - 2.2e-07 30.3 0.0 2.9e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EPS29803.1 - 0.0028 16.9 0.0 0.0065 15.7 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EPS29803.1 - 0.0055 15.8 0.0 0.0059 15.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EPS29803.1 - 0.02 14.4 0.0 1.5 8.3 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 EPS29803.1 - 0.089 12.7 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_21 PF13304.1 EPS29803.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain MRP-L28 PF09812.4 EPS29804.1 - 2.7e-08 33.7 0.1 3.7e-08 33.3 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Mfp-3 PF04202.8 EPS29804.1 - 0.05 13.7 0.6 0.43 10.7 0.0 2.1 2 0 0 2 2 2 0 Foot protein 3 RINGv PF12906.2 EPS29805.1 - 9.2e-06 25.6 5.7 1.8e-05 24.7 4.0 1.5 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.3 EPS29805.1 - 5.4e-05 23.0 2.7 0.00011 22.1 1.8 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.1 EPS29805.1 - 0.0035 17.1 4.3 0.0035 17.1 3.0 1.9 2 0 0 2 2 2 1 Ring finger domain Cytochrome-c551 PF10643.4 EPS29805.1 - 0.016 14.4 0.1 0.028 13.7 0.1 1.3 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Transthyretin PF00576.16 EPS29806.1 - 6.3e-21 74.3 0.0 2.2e-18 66.1 0.0 2.2 1 1 0 1 1 1 1 HIUase/Transthyretin family ArsA_ATPase PF02374.10 EPS29807.1 - 5.3e-116 386.9 0.0 6.1e-116 386.7 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 EPS29807.1 - 1.1e-16 60.8 0.3 1.7e-16 60.1 0.2 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EPS29807.1 - 1.7e-08 34.5 0.0 1.8e-07 31.1 0.0 2.4 2 1 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 EPS29807.1 - 1.6e-06 27.4 0.1 3.8e-06 26.2 0.0 1.6 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 EPS29807.1 - 4.1e-05 23.0 0.0 0.00066 19.1 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain PhoH PF02562.11 EPS29807.1 - 0.0078 15.4 0.1 0.022 14.0 0.0 1.7 2 0 0 2 2 2 1 PhoH-like protein AAA_19 PF13245.1 EPS29807.1 - 0.011 15.4 0.0 0.037 13.7 0.0 1.8 2 0 0 2 2 2 0 Part of AAA domain MipZ PF09140.6 EPS29807.1 - 0.016 14.3 0.2 0.042 12.9 0.0 1.8 2 0 0 2 2 2 0 ATPase MipZ AAA_25 PF13481.1 EPS29807.1 - 0.019 14.3 0.2 0.036 13.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EPS29807.1 - 0.023 14.1 0.0 0.043 13.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein YhjQ PF06564.7 EPS29807.1 - 0.028 13.7 0.0 0.063 12.6 0.0 1.5 2 0 0 2 2 2 0 YhjQ protein NB-ARC PF00931.17 EPS29807.1 - 0.062 12.1 0.1 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain T2SE PF00437.15 EPS29807.1 - 0.096 11.5 0.0 0.23 10.3 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein VirC1 PF07015.6 EPS29807.1 - 0.12 11.3 0.1 0.81 8.7 0.0 2.0 2 0 0 2 2 2 0 VirC1 protein A1_Propeptide PF07966.7 EPS29807.1 - 0.38 10.5 1.6 0.75 9.6 0.1 2.4 2 0 0 2 2 2 0 A1 Propeptide Amidase PF01425.16 EPS29808.1 - 5e-57 193.7 0.1 7.3e-55 186.5 0.0 2.7 1 1 1 2 2 2 2 Amidase eIF3_N PF09440.5 EPS29810.1 - 3.3e-52 176.1 1.7 7.4e-52 175.0 1.2 1.6 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 EPS29810.1 - 3.4e-14 53.0 0.0 9.6e-14 51.5 0.0 1.8 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 EPS29810.1 - 0.017 14.8 0.0 0.043 13.5 0.0 1.7 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 Img2 PF05046.9 EPS29811.1 - 6.7e-28 96.7 0.0 1.1e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SBP PF03110.9 EPS29811.1 - 0.011 15.9 1.0 0.02 15.1 0.7 1.4 1 0 0 1 1 1 0 SBP domain Flavoprotein PF02441.14 EPS29812.1 - 1.1e-39 135.0 0.2 1.4e-39 134.6 0.1 1.1 1 0 0 1 1 1 1 Flavoprotein ARID PF01388.16 EPS29813.1 - 3.3e-21 74.9 0.0 1.5e-20 72.8 0.0 2.2 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain AAA PF00004.24 EPS29814.1 - 2e-46 157.4 0.1 7.2e-46 155.6 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EPS29814.1 - 3.3e-09 36.5 0.6 1.1e-08 34.9 0.1 2.1 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EPS29814.1 - 4.3e-09 36.5 0.0 8.9e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EPS29814.1 - 1.6e-07 31.4 0.0 6.2e-07 29.5 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EPS29814.1 - 2.4e-06 27.7 2.6 0.0001 22.4 0.5 2.9 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 EPS29814.1 - 1.7e-05 24.6 0.0 6.5e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 EPS29814.1 - 5.6e-05 22.1 0.0 0.00011 21.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EPS29814.1 - 0.0002 22.1 0.1 0.0012 19.6 0.0 2.2 3 0 0 3 3 2 1 AAA domain RuvB_N PF05496.7 EPS29814.1 - 0.00041 19.4 0.0 0.00096 18.2 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus NTPase_1 PF03266.10 EPS29814.1 - 0.00067 19.4 0.0 0.002 17.8 0.0 1.8 2 0 0 2 2 1 1 NTPase Zeta_toxin PF06414.7 EPS29814.1 - 0.00074 18.6 0.1 0.002 17.2 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.7 EPS29814.1 - 0.00075 19.1 1.2 0.056 13.0 0.0 3.1 3 1 0 3 3 3 1 NACHT domain UPF0079 PF02367.12 EPS29814.1 - 0.0009 18.8 0.1 0.038 13.6 0.0 2.3 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 EPS29814.1 - 0.0012 18.7 0.0 0.0027 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EPS29814.1 - 0.0012 18.9 0.0 0.0025 17.9 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_19 PF13245.1 EPS29814.1 - 0.0012 18.5 0.1 0.0033 17.1 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EPS29814.1 - 0.0022 17.9 0.0 0.0051 16.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EPS29814.1 - 0.0032 17.0 0.0 0.0093 15.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 EPS29814.1 - 0.0036 16.0 0.0 0.0065 15.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_11 PF13086.1 EPS29814.1 - 0.004 16.7 0.4 0.014 14.9 0.0 2.0 2 1 1 3 3 3 1 AAA domain Sigma54_activat PF00158.21 EPS29814.1 - 0.0056 16.1 0.0 0.23 10.9 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_23 PF13476.1 EPS29814.1 - 0.0063 16.8 0.3 0.55 10.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EPS29814.1 - 0.0065 15.6 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EPS29814.1 - 0.0068 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EPS29814.1 - 0.0097 15.3 0.3 0.032 13.6 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.1 EPS29814.1 - 0.0098 15.3 2.2 0.049 13.0 0.0 2.5 2 1 1 3 3 3 1 AAA domain Arch_ATPase PF01637.13 EPS29814.1 - 0.013 15.1 1.0 0.15 11.6 0.0 2.6 2 1 1 3 3 3 0 Archaeal ATPase AAA_30 PF13604.1 EPS29814.1 - 0.021 14.4 0.0 0.083 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.13 EPS29814.1 - 0.028 14.0 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_18 PF13238.1 EPS29814.1 - 0.028 14.7 0.0 0.09 13.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain Cast PF10174.4 EPS29814.1 - 0.034 12.2 1.4 0.055 11.5 0.5 1.5 2 0 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone KaiC PF06745.8 EPS29814.1 - 0.037 13.1 0.9 0.46 9.5 0.0 2.5 3 0 0 3 3 3 0 KaiC Sigma54_activ_2 PF14532.1 EPS29814.1 - 0.083 12.9 0.0 0.39 10.7 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 EPS29814.1 - 0.11 12.8 0.1 0.46 10.7 0.0 2.2 3 0 0 3 3 2 0 ABC transporter Viral_Hsp90 PF03225.9 EPS29814.1 - 0.14 10.4 0.0 0.22 9.7 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue Parvo_NS1 PF01057.12 EPS29814.1 - 0.17 10.7 0.0 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Ank_2 PF12796.2 EPS29815.1 - 1.7e-57 191.7 13.6 4.5e-19 68.5 0.0 5.0 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EPS29815.1 - 1e-43 144.9 19.0 7.8e-06 25.4 0.1 9.9 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.1 EPS29815.1 - 4.6e-38 128.3 12.5 7e-08 32.4 0.1 8.2 3 1 5 8 8 8 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 EPS29815.1 - 2.1e-35 120.4 11.3 6.2e-06 26.5 0.1 8.5 4 2 6 10 10 9 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPS29815.1 - 1.6e-32 108.2 11.2 0.00024 21.0 0.0 10.2 10 0 0 10 10 10 6 Ankyrin repeat NACHT PF05729.7 EPS29815.1 - 3.9e-08 33.1 0.0 8.1e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EPS29815.1 - 2.7e-06 27.4 0.1 9.8e-06 25.6 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EPS29815.1 - 0.003 18.3 0.0 0.016 15.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPS29815.1 - 0.0032 17.7 0.0 0.008 16.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EPS29815.1 - 0.0045 17.1 0.0 0.016 15.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EPS29815.1 - 0.0081 16.3 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_29 PF13555.1 EPS29815.1 - 0.027 14.0 0.0 0.071 12.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TcdB_toxin_midC PF12255.3 EPS29815.1 - 0.029 14.0 0.0 0.064 12.9 0.0 1.5 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/C-terminal region AAA_33 PF13671.1 EPS29815.1 - 0.038 13.8 0.0 0.13 12.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EPS29815.1 - 0.049 13.0 0.0 0.14 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EPS29815.1 - 0.072 12.5 0.1 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain AAA_24 PF13479.1 EPS29815.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2802 PF10975.3 EPS29816.1 - 0.017 14.8 0.4 4.1 7.2 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2802) Asp PF00026.18 EPS29818.1 - 1.3e-105 353.1 0.0 1.8e-105 352.6 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EPS29818.1 - 9.5e-11 41.9 0.1 3.2e-10 40.1 0.1 2.0 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EPS29818.1 - 3.1e-06 27.5 0.3 0.016 15.6 0.0 3.3 3 2 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 EPS29818.1 - 4.9e-05 22.9 0.0 0.00074 19.0 0.0 2.6 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal NIF PF03031.13 EPS29819.1 - 4.2e-27 94.7 0.0 8.3e-27 93.8 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 EPS29819.1 - 3.4e-13 49.2 0.3 6.6e-13 48.3 0.2 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EPS29819.1 - 3.3e-07 30.3 0.0 8.5e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Biotin_lipoyl PF00364.17 EPS29819.1 - 0.04 13.5 0.0 15 5.3 0.0 2.9 3 0 0 3 3 3 0 Biotin-requiring enzyme Arginase PF00491.16 EPS29822.1 - 2e-77 260.1 0.8 2.4e-77 259.9 0.5 1.0 1 0 0 1 1 1 1 Arginase family GatB_N PF02934.10 EPS29823.1 - 1.7e-100 335.6 0.0 2.2e-100 335.2 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 EPS29823.1 - 5.2e-27 94.3 0.1 9.4e-27 93.5 0.1 1.4 1 0 0 1 1 1 1 GatB domain Cep57_MT_bd PF06657.8 EPS29825.1 - 0.039 13.8 1.0 0.12 12.3 0.7 1.7 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 DUF1117 PF06547.7 EPS29825.1 - 1.8 8.6 5.2 0.62 10.1 0.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1117) HeLo PF14479.1 EPS29826.1 - 0.0051 16.5 0.3 0.022 14.5 0.2 2.0 1 0 0 1 1 1 1 Prion-inhibition and propagation DUF3512 PF12024.3 EPS29826.1 - 0.034 13.4 0.3 0.11 11.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3512) ECH PF00378.15 EPS29828.1 - 1.7e-46 158.3 0.0 2.3e-46 157.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF2625 PF10946.3 EPS29828.1 - 0.086 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF2625 LmjF365940-deam PF14421.1 EPS29828.1 - 0.12 11.7 0.1 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases Abhydrolase_6 PF12697.2 EPS29829.1 - 1.7e-05 24.8 0.0 2.3e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EPS29829.1 - 6.2e-05 22.3 0.2 0.00034 19.9 0.0 1.9 2 0 0 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EPS29829.1 - 0.0043 16.6 0.0 0.0077 15.8 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Cutinase PF01083.17 EPS29829.1 - 0.011 15.4 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Cutinase Abhydrolase_5 PF12695.2 EPS29829.1 - 0.015 15.0 0.0 0.031 14.0 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family NB-ARC PF00931.17 EPS29830.1 - 4.6e-11 42.1 0.0 7.4e-11 41.4 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 EPS29830.1 - 4.6e-06 26.8 0.0 1.8e-05 24.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EPS29830.1 - 1e-05 25.6 0.0 3.1e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EPS29830.1 - 0.00018 21.1 0.0 0.00039 20.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Zeta_toxin PF06414.7 EPS29830.1 - 0.00024 20.2 0.1 0.00053 19.1 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin KaiC PF06745.8 EPS29830.1 - 0.00044 19.4 0.0 0.00081 18.5 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_17 PF13207.1 EPS29830.1 - 0.00058 20.6 0.0 0.0013 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EPS29830.1 - 0.019 14.8 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EPS29830.1 - 0.03 14.6 0.0 0.1 12.9 0.0 1.9 2 1 0 2 2 1 0 AAA domain AAA_10 PF12846.2 EPS29830.1 - 0.049 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain AAA_19 PF13245.1 EPS29830.1 - 0.071 12.8 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Viral_helicase1 PF01443.13 EPS29830.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.21 EPS29830.1 - 0.2 11.1 0.0 0.33 10.3 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain adh_short PF00106.20 EPS29831.1 - 4.3e-08 33.2 0.0 6.7e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPS29831.1 - 3.5e-06 26.7 0.0 5.9e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Zn_clus PF00172.13 EPS29832.1 - 0.0002 21.1 14.5 0.0002 21.1 10.0 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APH PF01636.18 EPS29835.1 - 5.8e-12 45.8 0.3 9.6e-12 45.1 0.2 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EPS29835.1 - 0.00082 18.1 0.0 0.067 11.8 0.0 2.2 2 1 0 2 2 2 2 Protein of unknown function (DUF1679) RIO1 PF01163.17 EPS29835.1 - 0.041 13.2 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 RIO1 family Choline_kinase PF01633.15 EPS29835.1 - 0.06 12.9 0.0 0.093 12.2 0.0 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase DUF883 PF05957.8 EPS29836.1 - 0.0013 19.1 10.2 0.0034 17.7 4.2 2.1 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF883) OmpH PF03938.9 EPS29836.1 - 0.076 12.9 5.3 0.095 12.6 3.7 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) YbjQ_1 PF01906.12 EPS29836.1 - 0.091 13.1 1.8 0.12 12.8 0.8 1.5 1 1 0 1 1 1 0 Putative heavy-metal-binding CsbD PF05532.7 EPS29836.1 - 0.14 11.8 22.5 1.2 8.8 13.2 3.4 1 1 1 2 2 2 0 CsbD-like Cytochrom_C_2 PF01322.15 EPS29836.1 - 0.54 10.8 7.6 0.72 10.4 5.3 1.2 1 0 0 1 1 1 0 Cytochrome C' DDHD PF02862.12 EPS29836.1 - 0.6 9.8 3.1 0.71 9.6 2.2 1.1 1 0 0 1 1 1 0 DDHD domain DivIVA PF05103.8 EPS29836.1 - 1.3 9.0 8.3 2.4 8.1 5.8 1.5 1 1 0 1 1 1 0 DivIVA protein YtxH PF12732.2 EPS29836.1 - 3.1 8.2 10.6 1 9.7 2.0 2.2 1 1 1 2 2 2 0 YtxH-like protein FHA PF00498.21 EPS29837.1 - 5.6e-14 52.0 0.4 1.3e-13 50.8 0.0 1.9 2 0 0 2 2 2 1 FHA domain MIP-T3 PF10243.4 EPS29837.1 - 6.2 5.1 32.3 7.7 4.8 22.4 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DnaJ PF00226.26 EPS29838.1 - 3.4e-10 39.5 0.4 7.4e-10 38.4 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain Abhydrolase_3 PF07859.8 EPS29839.1 - 6.1e-42 143.5 0.1 5.2e-40 137.2 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EPS29839.1 - 1e-08 34.2 0.0 2.3e-08 33.0 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EPS29839.1 - 0.0088 15.7 0.0 0.015 15.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Atg14 PF10186.4 EPS29840.1 - 1.9 7.3 7.1 0.072 12.0 0.6 1.7 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2955 PF11168.3 EPS29841.1 - 0.031 13.9 2.3 0.05 13.2 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2955) ATG11 PF10377.4 EPS29842.1 - 2e-40 137.6 0.1 2e-40 137.6 0.0 2.9 3 0 0 3 3 3 1 Autophagy-related protein 11 APG17 PF04108.7 EPS29842.1 - 2.2e-09 36.6 0.2 2.2e-09 36.6 0.1 5.4 2 2 1 4 4 4 3 Autophagy protein Apg17 Myosin_tail_1 PF01576.14 EPS29842.1 - 0.00073 17.3 21.8 0.00073 17.3 15.1 5.9 5 1 1 6 6 6 2 Myosin tail Fib_alpha PF08702.5 EPS29842.1 - 0.0034 17.4 2.1 0.0034 17.4 1.4 7.4 7 2 2 9 9 9 2 Fibrinogen alpha/beta chain family DUF1664 PF07889.7 EPS29842.1 - 0.58 9.9 40.9 2.9 7.7 0.5 7.7 8 1 0 8 8 8 0 Protein of unknown function (DUF1664) CENP-H PF05837.7 EPS29843.1 - 4.7e-30 103.8 9.6 4.7e-30 103.8 6.6 2.1 2 0 0 2 2 2 1 Centromere protein H (CENP-H) NCD1 PF04904.8 EPS29843.1 - 8.7e-05 22.1 0.7 0.36 10.6 0.1 2.5 1 1 1 2 2 2 2 NAB conserved region 1 (NCD1) DLD PF14878.1 EPS29843.1 - 0.024 14.7 1.2 0.024 14.7 0.9 2.0 2 0 0 2 2 2 0 Death-like domain of SPT6 THP2 PF09432.5 EPS29843.1 - 0.13 12.1 15.6 0.065 13.0 1.4 3.1 2 1 1 3 3 3 0 Tho complex subunit THP2 NTP_transf_5 PF14907.1 EPS29843.1 - 0.24 10.7 4.2 0.18 11.0 0.8 2.0 2 0 0 2 2 2 0 Uncharacterised nucleotidyltransferase APG6 PF04111.7 EPS29843.1 - 1.4 7.8 12.7 0.042 12.8 2.4 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 TBPIP PF07106.8 EPS29843.1 - 5.8 6.4 12.3 0.74 9.3 4.1 2.0 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) HMG_box PF00505.14 EPS29845.1 - 9.1e-26 89.9 2.9 1.2e-25 89.5 1.5 1.6 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EPS29845.1 - 1.4e-18 66.9 3.4 1.4e-18 66.9 2.4 1.7 2 0 0 2 2 2 1 HMG-box domain DUF1014 PF06244.7 EPS29845.1 - 0.002 18.3 1.2 0.0066 16.6 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1014) HMG_box_5 PF14887.1 EPS29845.1 - 0.0025 17.5 2.2 0.0054 16.4 1.5 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box 5 Homoserine_dh PF00742.14 EPS29849.1 - 4.7e-52 176.2 0.0 6.2e-52 175.8 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 EPS29849.1 - 2.3e-13 50.5 0.0 4.5e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF4078 PF13300.1 EPS29850.1 - 6.7e-26 90.2 11.8 2.7e-25 88.3 8.2 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4078) DUF221 PF02714.10 EPS29851.1 - 1.7e-94 316.3 20.3 1.7e-94 316.3 14.1 1.5 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EPS29851.1 - 6.3e-41 139.5 1.5 6.3e-41 139.5 1.0 2.4 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EPS29851.1 - 1.4e-13 51.1 0.2 3.7e-13 49.7 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4463) Dockerin_1 PF00404.13 EPS29851.1 - 0.38 10.5 2.8 1.8 8.4 0.0 2.5 2 0 0 2 2 2 0 Dockerin type I repeat F_bP_aldolase PF01116.15 EPS29852.1 - 4.9e-98 327.7 0.0 5.5e-98 327.6 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II UCH PF00443.24 EPS29854.1 - 1e-45 155.9 0.0 4.7e-39 134.1 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPS29854.1 - 5e-16 59.0 0.0 2.1e-15 56.9 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase AlaDh_PNT_N PF05222.10 EPS29855.1 - 9.6e-29 100.1 0.0 1.6e-28 99.4 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 EPS29855.1 - 2.2e-20 72.8 0.0 3.2e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Holin_LLH PF09682.5 EPS29856.1 - 0.031 14.4 0.3 0.059 13.4 0.2 1.5 1 0 0 1 1 1 0 Phage holin protein (Holin_LLH) DUF2993 PF11209.3 EPS29857.1 - 0.055 13.3 0.7 4.1 7.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2993) CUE PF02845.11 EPS29858.1 - 8e-12 44.4 0.0 1.2e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 CUE domain Oxysterol_BP PF01237.13 EPS29859.1 - 1.6e-89 299.8 0.3 1.8e-89 299.6 0.2 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein MFS_1 PF07690.11 EPS29860.1 - 7e-43 146.6 34.5 7e-43 146.6 23.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS29860.1 - 2.6e-09 36.1 8.2 2.6e-09 36.1 5.7 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter DUF4014 PF13198.1 EPS29860.1 - 0.18 12.2 0.7 16 5.9 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4014) ATG22 PF11700.3 EPS29861.1 - 1.9e-109 366.2 22.7 2.2e-109 366.0 15.7 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EPS29861.1 - 1.4e-09 37.1 11.0 1.4e-09 37.1 7.6 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 EPS29861.1 - 0.46 8.8 32.5 0.073 11.4 0.2 3.8 2 1 1 4 4 4 0 MFS/sugar transport protein MFS_1 PF07690.11 EPS29862.1 - 5.1e-39 133.9 58.2 3.2e-38 131.3 39.3 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPS29862.1 - 2.2e-10 39.3 32.4 8.3e-10 37.4 22.5 1.8 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) GerA PF03323.8 EPS29862.1 - 0.1 10.6 5.4 0.27 9.3 3.8 1.7 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein Glyco_hydro_3 PF00933.16 EPS29863.1 - 7.7e-63 212.2 0.0 1.1e-62 211.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Acetyltransf_1 PF00583.19 EPS29863.1 - 3.2e-13 49.4 0.0 4.9e-06 26.4 0.0 2.6 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPS29863.1 - 5.7e-13 48.8 0.0 4.8e-06 26.6 0.0 2.5 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPS29863.1 - 6.3e-07 29.5 0.0 3.6e-05 23.8 0.0 2.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPS29863.1 - 0.00052 19.8 0.0 0.015 15.1 0.0 2.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Glyco_hydro_3_C PF01915.17 EPS29863.1 - 0.022 14.3 0.0 0.044 13.2 0.0 1.5 1 1 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain Antibiotic_NAT PF02522.9 EPS29863.1 - 0.067 12.4 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Aminoglycoside 3-N-acetyltransferase MiaE_2 PF13794.1 EPS29864.1 - 0.041 13.3 0.0 0.059 12.8 0.0 1.2 1 0 0 1 1 1 0 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like GST_N_3 PF13417.1 EPS29865.1 - 1.2e-14 54.2 0.0 2.2e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EPS29865.1 - 4.3e-13 49.0 0.0 7.3e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EPS29865.1 - 8.9e-13 48.2 0.0 3.2e-12 46.4 0.0 1.9 2 1 1 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EPS29865.1 - 1.4e-10 40.9 0.0 2.8e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EPS29865.1 - 5e-07 29.5 0.0 1.7e-06 27.8 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EPS29865.1 - 1.3e-05 25.5 0.0 1.9e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RNase_T PF00929.19 EPS29867.1 - 7.6e-27 94.5 0.0 8.6e-27 94.4 0.0 1.0 1 0 0 1 1 1 1 Exonuclease PGM_PMM_I PF02878.11 EPS29868.1 - 5.9e-32 110.0 0.0 8.7e-32 109.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EPS29868.1 - 9.4e-26 90.0 0.0 1.8e-25 89.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EPS29868.1 - 3.4e-17 62.6 0.1 7.8e-17 61.5 0.1 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EPS29868.1 - 1.6e-09 37.6 0.0 4.2e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain GFO_IDH_MocA PF01408.17 EPS29869.1 - 2.3e-13 50.6 0.7 5.8e-12 46.1 0.5 2.4 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EPS29869.1 - 0.00048 19.9 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Sugar_tr PF00083.19 EPS29870.1 - 4.7e-82 275.9 28.8 5.7e-82 275.6 20.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS29870.1 - 2.7e-28 98.7 45.1 9.6e-23 80.4 12.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PsbJ PF01788.12 EPS29870.1 - 0.33 10.5 0.1 0.33 10.5 0.0 2.9 3 0 0 3 3 3 0 PsbJ K_oxygenase PF13434.1 EPS29871.1 - 2.4e-13 49.7 0.0 2.5e-07 29.9 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EPS29871.1 - 1e-11 45.2 0.0 0.00013 22.1 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPS29871.1 - 1.2e-05 25.1 0.0 0.15 11.8 0.0 3.3 4 0 0 4 4 4 2 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EPS29871.1 - 0.0004 20.4 3.8 0.0044 17.1 0.0 2.7 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 EPS29871.1 - 0.001 18.9 0.0 0.33 10.8 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPS29871.1 - 0.0039 16.3 0.1 0.042 12.9 0.0 2.3 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.7 EPS29871.1 - 0.0048 15.8 0.5 0.0097 14.8 0.1 1.8 2 1 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EPS29871.1 - 0.011 14.6 0.0 0.026 13.3 0.0 1.6 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 EPS29871.1 - 0.019 13.4 0.1 0.1 11.0 0.0 2.1 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_8 PF13450.1 EPS29871.1 - 0.019 14.9 0.0 0.28 11.2 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EPS29871.1 - 0.055 12.5 0.1 0.2 10.6 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Malic_M PF03949.10 EPS29871.1 - 0.14 11.7 1.2 6.6 6.1 0.0 2.9 3 0 0 3 3 3 0 Malic enzyme, NAD binding domain HMG_CoA_synt_C PF08540.5 EPS29873.1 - 2e-103 345.7 1.3 2.5e-103 345.4 0.9 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EPS29873.1 - 4.5e-96 319.3 0.1 6.9e-96 318.7 0.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal Ribosomal_L22e PF01776.12 EPS29875.1 - 9.6e-50 167.2 0.5 1.2e-49 166.9 0.3 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family TFIIA PF03153.8 EPS29876.1 - 3 7.6 7.6 4.2 7.1 5.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF676 PF05057.9 EPS29877.1 - 4.9e-50 169.8 0.0 7.3e-50 169.2 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EPS29877.1 - 1.5e-06 28.3 0.0 2.5e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EPS29877.1 - 4.8e-06 26.3 0.0 8.7e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EPS29877.1 - 7.2e-05 22.5 0.0 0.00014 21.6 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 EPS29877.1 - 0.01 14.8 0.0 0.02 13.8 0.0 1.4 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.20 EPS29877.1 - 0.011 15.3 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Lipase_2 PF01674.13 EPS29877.1 - 0.031 13.5 0.0 0.056 12.7 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 2) DUF915 PF06028.6 EPS29877.1 - 0.052 12.6 0.2 0.6 9.1 0.0 2.5 2 1 1 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_2 PF02230.11 EPS29877.1 - 0.1 12.0 0.1 1 8.7 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase tRNA_SAD PF07973.9 EPS29878.1 - 7.3e-11 41.7 0.3 1.3e-10 40.9 0.2 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.14 EPS29878.1 - 2.3e-09 36.1 0.0 2.8e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) Hydrolase_6 PF13344.1 EPS29879.1 - 3.5e-22 78.1 0.0 6.6e-22 77.3 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EPS29879.1 - 6.2e-09 35.4 0.0 5e-08 32.5 0.0 2.4 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 EPS29879.1 - 0.026 14.7 0.0 5.3 7.2 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase CFEM PF05730.6 EPS29880.1 - 0.00019 21.1 4.8 0.00037 20.2 3.3 1.4 1 0 0 1 1 1 1 CFEM domain Rax2 PF12768.2 EPS29880.1 - 0.0022 17.2 0.5 0.0036 16.5 0.3 1.3 1 0 0 1 1 1 1 Cortical protein marker for cell polarity TMEM154 PF15102.1 EPS29880.1 - 0.77 9.4 8.3 0.03 14.0 0.6 2.1 1 1 1 2 2 2 0 TMEM154 protein family Plasmodium_Vir PF05795.6 EPS29880.1 - 2 7.5 4.3 4.7 6.3 1.5 2.0 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Pmp3 PF01679.12 EPS29881.1 - 2.3e-26 91.2 5.9 2.6e-26 91.0 4.1 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TM_helix PF05552.7 EPS29881.1 - 3.6 7.3 8.0 0.24 11.1 1.9 1.7 2 0 0 2 2 2 0 Conserved TM helix ATP-synt_C PF00137.16 EPS29883.1 - 1e-31 108.6 28.4 7.7e-18 64.1 8.7 2.0 2 0 0 2 2 2 2 ATP synthase subunit C Flavi_NS4A PF01350.12 EPS29883.1 - 0.18 11.3 3.6 0.07 12.6 0.6 1.6 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A DUF1713 PF08213.6 EPS29884.1 - 4.7e-11 42.0 22.0 9.2e-11 41.1 15.3 1.5 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Pet20 PF08692.5 EPS29884.1 - 0.059 13.3 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial protein Pet20 Mito_fiss_reg PF05308.6 EPS29884.1 - 0.082 12.2 5.3 0.07 12.4 0.3 2.4 2 0 0 2 2 2 0 Mitochondrial fission regulator G-alpha PF00503.15 EPS29885.1 - 1.3e-111 373.0 0.0 1.6e-111 372.7 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EPS29885.1 - 4.3e-14 52.1 0.1 3.1e-09 36.3 0.0 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EPS29885.1 - 1.5e-07 30.7 0.3 0.00016 20.8 0.0 2.2 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 EPS29885.1 - 0.013 15.9 0.0 0.67 10.4 0.0 2.6 2 1 0 2 2 2 0 Miro-like protein GTP_EFTU PF00009.22 EPS29885.1 - 0.025 14.0 0.0 1.4 8.3 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EPS29885.1 - 0.026 14.4 0.0 6.6 6.7 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.1 EPS29885.1 - 0.027 13.9 0.1 0.057 12.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Peptidase_M13_N PF05649.8 EPS29887.1 - 7.3e-90 301.8 0.0 1.1e-89 301.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 EPS29887.1 - 2.5e-55 186.8 0.0 3.8e-55 186.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M13 RasGEF PF00617.14 EPS29889.1 - 3.3e-46 157.4 0.5 4.9e-46 156.8 0.3 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EPS29889.1 - 1.5e-13 50.7 0.2 3e-13 49.7 0.1 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif Ank_2 PF12796.2 EPS29890.1 - 3e-19 69.1 0.1 1.6e-18 66.8 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) DIL PF01843.14 EPS29890.1 - 4.3e-18 65.1 3.1 5.1e-16 58.4 2.1 2.6 1 1 0 1 1 1 1 DIL domain Ank PF00023.25 EPS29890.1 - 1.2e-15 56.3 0.1 1.5e-05 24.5 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EPS29890.1 - 1.1e-14 54.0 0.0 7.9e-06 25.9 0.0 3.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EPS29890.1 - 1e-10 41.8 0.1 0.0018 18.7 0.0 3.9 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPS29890.1 - 6.8e-09 35.1 0.9 0.0046 17.0 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat DUF2360 PF10152.4 EPS29890.1 - 0.36 11.1 4.6 0.46 10.7 0.3 2.6 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein (DUF2360) Merozoite_SPAM PF07133.6 EPS29891.1 - 1.3 8.9 7.2 1.4 8.8 3.9 1.8 1 1 1 2 2 2 0 Merozoite surface protein (SPAM) MFS_1 PF07690.11 EPS29893.1 - 4.8e-36 124.1 30.3 6.2e-36 123.8 21.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily YesK PF14150.1 EPS29893.1 - 0.03 14.4 1.2 0.03 14.4 0.9 3.5 3 0 0 3 3 3 0 YesK-like protein 3HCDH_N PF02737.13 EPS29894.1 - 6.3e-34 117.1 0.0 1e-33 116.5 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EPS29894.1 - 1.4e-14 54.2 0.0 2.8e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EPS29894.1 - 4.3e-06 26.6 0.1 8.5e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EPS29894.1 - 4.9e-06 26.8 0.3 1.5e-05 25.3 0.2 1.9 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 EPS29894.1 - 9.6e-06 25.4 0.1 1.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 EPS29894.1 - 0.0027 16.8 0.0 0.0058 15.8 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.19 EPS29894.1 - 0.0051 15.7 0.0 0.0087 14.9 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.11 EPS29894.1 - 0.0063 15.9 0.0 0.014 14.8 0.0 1.6 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 EPS29894.1 - 0.0095 15.3 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 EPS29894.1 - 0.034 14.1 0.1 0.092 12.7 0.1 1.8 1 1 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.1 EPS29894.1 - 0.035 14.3 0.0 0.064 13.5 0.0 1.5 1 1 0 1 1 1 0 Putative NAD(P)-binding IlvN PF07991.7 EPS29894.1 - 0.06 12.7 0.0 0.16 11.3 0.0 1.7 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Shikimate_DH PF01488.15 EPS29894.1 - 0.062 13.4 0.0 0.16 12.0 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase RabGAP-TBC PF00566.13 EPS29895.1 - 1.9e-33 115.7 0.0 3e-33 115.1 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Mo25 PF08569.6 EPS29896.1 - 2.3e-128 427.9 0.6 2.6e-128 427.7 0.4 1.0 1 0 0 1 1 1 1 Mo25-like Methyltransf_31 PF13847.1 EPS29897.1 - 1.5e-11 44.1 0.0 3.1e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS29897.1 - 3.8e-09 37.1 0.0 9.7e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPS29897.1 - 5.7e-09 36.3 0.0 1.6e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EPS29897.1 - 3e-08 33.1 0.0 5.9e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EPS29897.1 - 8.1e-07 29.0 0.0 1.6e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPS29897.1 - 8.1e-06 25.3 0.1 1.5e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EPS29897.1 - 9.3e-06 25.4 0.0 1.9e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPS29897.1 - 0.00054 20.2 0.0 0.0019 18.5 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EPS29897.1 - 0.0028 16.4 0.0 0.0043 15.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_12 PF08242.7 EPS29897.1 - 0.0045 17.4 0.0 0.014 15.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EPS29897.1 - 0.0063 15.6 0.2 0.015 14.5 0.2 1.6 1 1 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.14 EPS29897.1 - 0.018 14.5 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 EPS29897.1 - 0.018 14.1 0.0 0.038 13.0 0.0 1.5 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 EPS29897.1 - 0.028 14.4 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Met_10 PF02475.11 EPS29897.1 - 0.034 13.7 0.1 0.064 12.8 0.1 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_24 PF13578.1 EPS29897.1 - 0.043 14.6 0.0 0.13 13.1 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EPS29897.1 - 0.051 12.6 0.0 0.09 11.8 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Surfac_D-trimer PF09006.6 EPS29897.1 - 0.16 11.6 0.4 0.43 10.3 0.3 1.7 1 0 0 1 1 1 0 Lung surfactant protein D coiled-coil trimerisation IncA PF04156.9 EPS29897.1 - 0.45 10.0 3.5 0.88 9.1 2.4 1.4 1 0 0 1 1 1 0 IncA protein Cir_N PF10197.4 EPS29898.1 - 0.0037 17.2 3.2 0.0037 17.2 2.2 3.9 4 1 0 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR AAA PF00004.24 EPS29899.1 - 7.9e-54 181.4 0.0 7.4e-39 132.9 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EPS29899.1 - 2.4e-12 46.6 0.0 4.9e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain CDC48_2 PF02933.12 EPS29899.1 - 1.9e-10 40.2 0.2 4.9e-09 35.7 0.0 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_22 PF13401.1 EPS29899.1 - 2.6e-10 40.5 0.2 0.00054 20.1 0.0 4.0 2 2 0 3 3 3 2 AAA domain AAA_5 PF07728.9 EPS29899.1 - 1.5e-08 34.4 0.0 0.00092 18.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EPS29899.1 - 3.1e-08 33.5 0.0 0.0045 16.9 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_19 PF13245.1 EPS29899.1 - 3.3e-08 33.1 1.0 0.012 15.3 0.0 3.1 3 0 0 3 3 3 2 Part of AAA domain Mg_chelatase PF01078.16 EPS29899.1 - 4.2e-08 32.6 0.1 0.0039 16.3 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 EPS29899.1 - 4.9e-08 33.1 0.0 0.0062 16.5 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.1 EPS29899.1 - 1.8e-07 31.0 0.0 0.0035 17.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EPS29899.1 - 1.9e-07 31.9 0.0 0.012 16.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 EPS29899.1 - 3.3e-07 30.3 0.0 9.8e-05 22.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 EPS29899.1 - 3.4e-07 30.6 0.0 0.027 14.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain RuvB_N PF05496.7 EPS29899.1 - 8.8e-07 28.2 0.3 0.047 12.7 0.0 2.9 3 1 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EPS29899.1 - 1.4e-06 27.2 0.1 0.021 13.5 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_24 PF13479.1 EPS29899.1 - 1.7e-06 27.7 0.4 0.15 11.5 0.1 3.5 3 0 0 3 3 3 2 AAA domain IstB_IS21 PF01695.12 EPS29899.1 - 8.4e-06 25.3 0.2 0.055 12.8 0.0 2.7 3 0 0 3 3 3 2 IstB-like ATP binding protein RNA_helicase PF00910.17 EPS29899.1 - 1.5e-05 25.0 0.0 0.054 13.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.1 EPS29899.1 - 7.2e-05 22.2 2.0 0.86 8.9 0.0 3.7 2 2 2 4 4 4 2 AAA domain Zeta_toxin PF06414.7 EPS29899.1 - 7.4e-05 21.9 0.0 0.17 10.9 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin NACHT PF05729.7 EPS29899.1 - 0.00014 21.5 0.4 0.078 12.6 0.0 2.8 3 0 0 3 3 2 1 NACHT domain KaiC PF06745.8 EPS29899.1 - 0.00023 20.3 0.1 0.066 12.3 0.1 2.4 2 0 0 2 2 2 1 KaiC PhoH PF02562.11 EPS29899.1 - 0.00039 19.7 0.2 0.43 9.7 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein Arch_ATPase PF01637.13 EPS29899.1 - 0.00045 20.0 0.7 10 5.7 0.1 4.0 2 2 1 3 3 3 0 Archaeal ATPase AAA_28 PF13521.1 EPS29899.1 - 0.00045 20.2 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.22 EPS29899.1 - 0.00054 20.2 0.2 0.047 13.9 0.1 2.6 2 0 0 2 2 2 1 ABC transporter Sigma54_activat PF00158.21 EPS29899.1 - 0.0012 18.3 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.6 EPS29899.1 - 0.0013 18.3 0.0 0.38 10.3 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 EPS29899.1 - 0.0016 18.4 0.0 1.8 8.6 0.0 2.9 2 1 0 2 2 2 1 Sigma-54 interaction domain NB-ARC PF00931.17 EPS29899.1 - 0.0026 16.6 0.5 1.8 7.3 0.1 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_11 PF13086.1 EPS29899.1 - 0.0039 16.7 0.0 1.4 8.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 EPS29899.1 - 0.0045 16.0 0.0 0.45 9.4 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) UPF0079 PF02367.12 EPS29899.1 - 0.0069 16.0 0.1 1.7 8.2 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 DEAD PF00270.24 EPS29899.1 - 0.0098 15.4 0.1 5.6 6.4 0.0 3.8 2 2 0 3 3 3 0 DEAD/DEAH box helicase KTI12 PF08433.5 EPS29899.1 - 0.014 14.6 0.1 1.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Parvo_NS1 PF01057.12 EPS29899.1 - 0.02 13.7 0.0 0.78 8.5 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 KAP_NTPase PF07693.9 EPS29899.1 - 0.028 13.4 0.0 3.2 6.6 0.0 3.0 3 1 0 3 3 3 0 KAP family P-loop domain AAA_30 PF13604.1 EPS29899.1 - 0.032 13.8 0.0 2 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 EPS29899.1 - 0.085 12.6 0.1 17 5.2 0.0 2.7 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Zot PF05707.7 EPS29899.1 - 0.1 12.0 0.0 3.9 6.9 0.0 2.4 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_29 PF13555.1 EPS29899.1 - 0.12 11.9 0.1 5.4 6.6 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain KxDL PF10241.4 EPS29900.1 - 6.5e-35 118.9 0.4 8.2e-35 118.5 0.3 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein HATPase_c PF02518.21 EPS29904.1 - 2.8e-23 81.7 0.1 6.6e-23 80.5 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EPS29904.1 - 1.2e-21 76.8 0.2 3.6e-21 75.2 0.0 1.9 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EPS29904.1 - 5e-18 64.8 0.1 1.6e-17 63.2 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 EPS29904.1 - 1.4e-13 51.0 0.0 4.1e-07 30.3 0.0 3.2 3 0 0 3 3 3 2 PAS domain PAS_3 PF08447.6 EPS29904.1 - 1e-11 44.7 0.5 0.0035 17.4 0.1 4.0 3 1 1 4 4 4 3 PAS fold PAS_4 PF08448.5 EPS29904.1 - 7e-09 35.7 0.1 1.2e-06 28.5 0.0 3.3 3 0 0 3 3 3 1 PAS fold PAS PF00989.19 EPS29904.1 - 2.6e-06 27.2 0.0 0.036 13.8 0.0 2.9 2 0 0 2 2 2 2 PAS fold HATPase_c_2 PF13581.1 EPS29904.1 - 0.043 13.6 0.0 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain MotA_ExbB PF01618.11 EPS29904.1 - 0.24 11.0 0.6 0.7 9.5 0.0 2.0 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family HATPase_c PF02518.21 EPS29906.1 - 4.4e-29 100.4 0.0 1.1e-28 99.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EPS29906.1 - 2.7e-21 75.6 0.3 9.9e-21 73.8 0.0 2.2 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EPS29906.1 - 3.9e-20 71.5 0.0 1.3e-19 69.8 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.1 EPS29906.1 - 1e-11 45.5 0.0 2.3e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 GAF domain AAA_16 PF13191.1 EPS29906.1 - 6.9e-11 42.4 0.2 6.3e-10 39.3 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain GAF_3 PF13492.1 EPS29906.1 - 4e-08 33.4 0.2 1.5e-07 31.5 0.0 2.1 2 0 0 2 2 2 1 GAF domain Pkinase PF00069.20 EPS29906.1 - 3.1e-07 29.7 0.0 1.4e-06 27.6 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain GAF PF01590.21 EPS29906.1 - 9.7e-06 25.7 0.0 5.3e-05 23.3 0.0 2.3 3 0 0 3 3 2 1 GAF domain NB-ARC PF00931.17 EPS29906.1 - 1.8e-05 23.7 0.1 0.0019 17.0 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain HATPase_c_3 PF13589.1 EPS29906.1 - 0.047 13.3 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TPR_11 PF13414.1 EPS29906.1 - 0.062 12.9 0.4 6.5 6.4 0.0 3.1 2 0 0 2 2 2 0 TPR repeat BCL9 PF11502.3 EPS29906.1 - 0.12 11.8 0.0 0.5 9.9 0.1 2.0 2 0 0 2 2 2 0 B-cell lymphoma 9 protein Sugar_tr PF00083.19 EPS29907.1 - 9.7e-63 212.3 31.1 1.2e-62 212.0 21.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS29907.1 - 6.2e-25 87.6 29.2 8.8e-25 87.1 20.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Glyco_hyd_65N_2 PF14498.1 EPS29908.1 - 3.2e-63 213.5 0.0 5.2e-63 212.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_1 PF00232.13 EPS29909.1 - 5.3e-146 486.3 0.8 6.6e-146 486.0 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Cytochrom_B561 PF03188.11 EPS29911.1 - 2.3e-17 63.1 5.2 2.3e-17 63.1 3.6 1.8 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 Cytochrom_B_N PF00033.14 EPS29911.1 - 0.057 12.7 12.6 0.35 10.2 3.8 2.5 1 1 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB DUF1056 PF06341.6 EPS29911.1 - 0.1 12.6 9.2 1 9.4 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1056) PepSY_TM_3 PF13706.1 EPS29911.1 - 0.12 11.8 4.5 0.89 9.0 0.1 2.9 2 0 0 2 2 2 0 PepSY-associated TM helix DUF4079 PF13301.1 EPS29911.1 - 0.18 11.8 15.8 0.028 14.4 4.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) DUF2929 PF11151.3 EPS29911.1 - 6.2 6.9 9.4 1.3 9.1 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2929) DUF2306 PF10067.4 EPS29911.1 - 7.7 6.6 13.1 0.49 10.5 0.7 3.3 2 1 1 3 3 3 0 Predicted membrane protein (DUF2306) CytB6-F_Fe-S PF08802.5 EPS29911.1 - 9.2 6.3 6.6 0.83 9.7 0.4 2.3 2 0 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit tRNA-synt_2b PF00587.20 EPS29912.1 - 1.2e-21 77.0 0.0 3.7e-21 75.4 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EPS29912.1 - 2.7e-08 33.7 6.3 3.8e-07 30.0 4.4 2.2 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain GOLGA2L5 PF15070.1 EPS29912.1 - 0.0015 17.1 4.1 0.0022 16.6 2.9 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 BLOC1_2 PF10046.4 EPS29912.1 - 0.012 15.7 0.9 0.077 13.1 0.2 2.4 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-F_leu_zip PF10473.4 EPS29912.1 - 0.066 13.0 8.9 1.6 8.6 5.7 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.6 EPS29912.1 - 0.12 12.2 8.7 0.23 11.2 6.1 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF724 PF05266.9 EPS29912.1 - 0.41 10.2 3.3 0.69 9.5 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) IncA PF04156.9 EPS29912.1 - 0.48 9.9 12.2 0.82 9.2 8.4 1.3 1 0 0 1 1 1 0 IncA protein TBPIP PF07106.8 EPS29912.1 - 0.49 9.9 6.7 5.3 6.5 0.7 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) CENP-Q PF13094.1 EPS29912.1 - 0.53 10.2 11.2 0.58 10.1 7.0 1.5 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit NUDE_C PF04880.8 EPS29912.1 - 0.55 10.5 6.8 3.5 7.9 0.5 2.5 1 1 1 2 2 2 0 NUDE protein, C-terminal conserved region TMF_DNA_bd PF12329.3 EPS29912.1 - 0.66 9.8 9.8 0.05 13.4 1.8 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF342 PF03961.8 EPS29912.1 - 0.69 8.2 3.9 0.98 7.7 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TMF_TATA_bd PF12325.3 EPS29912.1 - 1.7 8.4 6.8 21 4.8 4.7 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding bZIP_1 PF00170.16 EPS29912.1 - 2.5 8.1 12.7 1.5 8.8 0.1 3.3 3 0 0 3 3 3 0 bZIP transcription factor TPR_MLP1_2 PF07926.7 EPS29912.1 - 2.7 7.7 10.6 3.6 7.3 6.5 1.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein APG6 PF04111.7 EPS29912.1 - 5.5 5.9 9.1 14 4.6 6.3 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 Striatin PF08232.7 EPS29912.1 - 7.8 6.8 8.8 3 8.1 3.9 1.9 1 1 1 2 2 2 0 Striatin family Mnd1 PF03962.10 EPS29912.1 - 9.7 5.8 9.2 2.6 7.6 4.2 1.6 2 0 0 2 2 2 0 Mnd1 family Bromodomain PF00439.20 EPS29913.1 - 5.5e-18 64.6 2.4 8e-17 60.9 0.1 2.6 2 0 0 2 2 2 1 Bromodomain Bromo_TP PF07524.8 EPS29913.1 - 1.4e-09 37.5 0.1 4.2e-09 36.0 0.0 1.8 2 0 0 2 2 2 1 Bromodomain associated Inhibitor_I53 PF11714.3 EPS29913.1 - 5.2 7.1 8.4 0.65 10.0 2.5 2.0 2 0 0 2 2 2 0 Thrombin inhibitor Madanin VanZ PF04892.7 EPS29914.1 - 3.9e-12 46.2 1.4 6.6e-12 45.5 1.0 1.3 1 1 0 1 1 1 1 VanZ like family DUF4401 PF14351.1 EPS29914.1 - 0.007 15.3 0.4 0.0089 15.0 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4401) DUF4383 PF14325.1 EPS29914.1 - 0.16 11.9 2.0 0.5 10.3 0.4 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4383) TrkH PF02386.11 EPS29914.1 - 0.24 9.9 1.9 2.3 6.7 1.3 2.1 1 1 0 1 1 1 0 Cation transport protein DUF3094 PF11293.3 EPS29914.1 - 0.35 10.3 2.7 6.8 6.2 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) DUF4131 PF13567.1 EPS29914.1 - 8.1 5.8 7.5 17 4.7 3.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Y_phosphatase PF00102.22 EPS29915.1 - 1.8e-51 174.7 0.0 9.3e-51 172.4 0.0 1.9 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EPS29915.1 - 0.0026 18.0 0.0 0.006 16.8 0.0 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EPS29915.1 - 0.0063 16.5 0.0 0.015 15.3 0.0 1.7 2 0 0 2 2 2 1 Inositol hexakisphosphate DSPc PF00782.15 EPS29915.1 - 0.018 14.6 1.4 0.12 11.9 0.9 2.2 1 1 1 2 2 2 0 Dual specificity phosphatase, catalytic domain BTB PF00651.26 EPS29916.1 - 0.044 13.7 0.0 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 BTB/POZ domain Piwi PF02171.12 EPS29917.1 - 1.1e-65 221.5 0.0 2.2e-65 220.5 0.0 1.4 2 0 0 2 2 2 1 Piwi domain PAZ PF02170.17 EPS29917.1 - 2e-15 56.2 0.0 4.1e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 EPS29917.1 - 1e-06 28.0 0.0 2.3e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Suf PF05843.9 EPS29918.1 - 1.1e-87 294.3 0.0 1.1e-87 294.3 0.0 3.9 4 1 0 4 4 4 1 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EPS29918.1 - 0.00019 21.7 2.4 0.048 14.3 0.2 4.7 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EPS29918.1 - 0.00027 21.5 2.6 0.019 15.6 0.2 3.7 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EPS29918.1 - 0.035 14.4 0.0 8.3 6.8 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat ASF1_hist_chap PF04729.8 EPS29919.1 - 1.3e-66 222.9 0.0 2.1e-66 222.3 0.0 1.3 1 0 0 1 1 1 1 ASF1 like histone chaperone Nop14 PF04147.7 EPS29919.1 - 0.096 10.5 27.2 0.13 10.1 18.9 1.1 1 0 0 1 1 1 0 Nop14-like family Lgl_C PF08596.5 EPS29920.1 - 6.2e-133 443.0 0.0 1.9e-132 441.4 0.0 1.7 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 EPS29920.1 - 1.6e-05 24.5 0.4 0.44 10.5 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat KTSC PF13619.1 EPS29920.1 - 0.18 11.4 0.1 0.74 9.4 0.0 2.0 2 0 0 2 2 2 0 KTSC domain Nup160 PF11715.3 EPS29920.1 - 0.27 9.3 0.0 0.98 7.4 0.0 1.9 3 0 0 3 3 3 0 Nucleoporin Nup120/160 APH PF01636.18 EPS29921.1 - 3.1e-07 30.3 0.0 4.9e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family THUMP PF02926.12 EPS29922.1 - 1.3e-14 54.2 0.3 2.2e-14 53.5 0.2 1.3 1 0 0 1 1 1 1 THUMP domain Cwf_Cwc_15 PF04889.7 EPS29922.1 - 0.12 12.0 3.3 0.19 11.4 2.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein TPP_enzyme_N PF02776.13 EPS29923.1 - 8.8e-37 126.2 0.0 1.5e-36 125.4 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EPS29923.1 - 4.8e-26 91.1 0.0 1.7e-25 89.3 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EPS29923.1 - 2.4e-16 59.6 0.0 4.7e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 EPS29923.1 - 0.0013 17.5 0.0 0.0024 16.6 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Abhydrolase_1 PF00561.15 EPS29923.1 - 0.049 13.1 0.0 0.098 12.1 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Pkinase PF00069.20 EPS29924.1 - 1.7e-63 214.1 0.0 2.6e-63 213.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS29924.1 - 3.9e-44 150.6 0.0 5.7e-44 150.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPS29924.1 - 8.1e-09 34.8 0.0 3.8e-07 29.3 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EPS29924.1 - 0.016 14.3 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sec34 PF04136.10 EPS29925.1 - 2e-29 102.3 0.9 4.5e-29 101.1 0.6 1.6 1 0 0 1 1 1 1 Sec34-like family Exo70 PF03081.10 EPS29925.1 - 0.0004 19.2 0.1 0.83 8.3 0.0 2.6 2 0 0 2 2 2 2 Exo70 exocyst complex subunit RCC1 PF00415.13 EPS29926.1 - 1.1e-26 92.7 6.3 1.2e-06 28.6 0.0 7.2 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EPS29926.1 - 4.8e-20 70.6 10.3 4.2e-13 48.5 0.1 5.5 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat PQQ_3 PF13570.1 EPS29926.1 - 0.043 14.0 0.1 2.1 8.7 0.0 3.4 3 0 0 3 3 3 0 PQQ-like domain DUF3639 PF12341.3 EPS29926.1 - 0.067 13.2 0.1 0.98 9.4 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3639) adh_short PF00106.20 EPS29927.1 - 9.2e-16 58.1 0.0 1.3e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPS29927.1 - 2.3e-06 27.5 0.0 3.4e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPS29927.1 - 5.7e-05 22.8 0.0 7.9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 KR domain PUF PF00806.14 EPS29928.1 - 2e-11 42.6 0.0 0.71 9.4 0.0 7.1 7 0 0 7 7 7 4 Pumilio-family RNA binding repeat Pectate_lyase22 PF14583.1 EPS29928.1 - 0.078 11.4 0.0 0.13 10.6 0.0 1.3 1 0 0 1 1 1 0 Oligogalacturonate lyase DUF488 PF04343.8 EPS29928.1 - 0.091 13.1 0.6 1.3 9.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF488 Metallopep PF12044.3 EPS29931.1 - 1.2e-170 567.5 0.0 1.6e-170 567.1 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.12 EPS29931.1 - 0.00071 19.4 0.1 0.052 13.4 0.0 2.4 1 1 1 2 2 2 2 Jacalin-like lectin domain Reprolysin_5 PF13688.1 EPS29931.1 - 0.0041 17.0 0.1 0.0073 16.2 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 RNA_polI_A34 PF08208.6 EPS29932.1 - 0.0017 18.0 7.0 0.0018 17.9 4.8 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 GBP_C PF02841.9 EPS29932.1 - 0.0038 16.4 2.4 0.0038 16.4 1.7 1.0 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain AIF_C PF14721.1 EPS29932.1 - 0.05 13.8 1.4 0.064 13.5 1.0 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF694 PF05107.7 EPS29932.1 - 0.098 11.8 5.0 0.12 11.5 3.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF694) DDHD PF02862.12 EPS29932.1 - 1.2 8.9 4.3 1.4 8.7 3.0 1.1 1 0 0 1 1 1 0 DDHD domain YqfQ PF14181.1 EPS29932.1 - 1.3 8.9 6.8 1.6 8.7 4.7 1.1 1 0 0 1 1 1 0 YqfQ-like protein Atrophin-1 PF03154.10 EPS29932.1 - 1.6 6.7 13.4 2 6.4 9.3 1.1 1 0 0 1 1 1 0 Atrophin-1 family Peptidase_S49_N PF08496.5 EPS29932.1 - 9.2 6.0 8.8 11 5.7 6.1 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CP2 PF04516.10 EPS29934.1 - 1.1e-85 286.5 0.0 1.8e-85 285.7 0.0 1.3 1 0 0 1 1 1 1 CP2 transcription factor ubiquitin PF00240.18 EPS29934.1 - 0.35 10.3 1.5 13 5.2 0.0 2.7 2 0 0 2 2 2 0 Ubiquitin family PNP_UDP_1 PF01048.15 EPS29935.1 - 0.078 11.9 0.0 0.093 11.6 0.0 1.2 1 0 0 1 1 1 0 Phosphorylase superfamily DNA_ligase_A_M PF01068.16 EPS29937.1 - 4e-50 170.0 0.1 2.9e-47 160.6 0.0 2.2 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EPS29937.1 - 1.2e-43 149.0 0.1 2e-43 148.2 0.1 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EPS29937.1 - 1.8e-19 69.8 0.0 7.5e-19 67.9 0.0 2.1 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RINT1_TIP1 PF04437.8 EPS29938.1 - 5e-179 595.9 0.0 1.6e-178 594.3 0.0 1.7 2 0 0 2 2 2 1 RINT-1 / TIP-1 family TPR_11 PF13414.1 EPS29938.1 - 0.035 13.7 0.5 0.12 12.0 0.3 2.0 2 0 0 2 2 2 0 TPR repeat TPR_16 PF13432.1 EPS29938.1 - 0.077 13.6 5.8 0.24 12.1 1.9 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2361 PF10153.4 EPS29938.1 - 0.088 12.9 6.5 0.19 11.9 4.5 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) Mo25 PF08569.6 EPS29938.1 - 0.11 11.5 0.8 0.28 10.1 0.0 1.9 1 1 1 2 2 2 0 Mo25-like Acyl-CoA_dh_C PF12806.2 EPS29938.1 - 0.32 10.8 6.4 7.3 6.4 2.7 3.2 2 1 1 3 3 3 0 Acetyl-CoA dehydrogenase C-terminal like DivIVA PF05103.8 EPS29938.1 - 3 7.8 11.1 6.1 6.9 6.8 2.2 2 1 0 2 2 2 0 DivIVA protein Pyridoxal_deC PF00282.14 EPS29939.1 - 5.1e-78 262.1 0.0 2e-76 256.8 0.0 2.3 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EPS29939.1 - 0.00012 20.9 0.0 0.0002 20.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EPS29939.1 - 0.0019 17.3 0.0 0.0033 16.6 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Trp_syntA PF00290.15 EPS29940.1 - 4.2e-92 307.3 0.0 6.7e-92 306.6 0.0 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 EPS29940.1 - 7.8e-45 153.4 1.2 1.3e-44 152.6 0.9 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Clathrin PF00637.15 EPS29941.1 - 5.4e-21 74.6 0.3 2.5e-19 69.2 0.1 2.8 3 0 0 3 3 3 1 Region in Clathrin and VPS WD40 PF00400.27 EPS29941.1 - 3e-05 23.6 2.6 0.0054 16.5 0.8 3.9 3 1 0 3 3 3 1 WD domain, G-beta repeat zf-RING_5 PF14634.1 EPS29941.1 - 0.025 14.3 0.2 0.049 13.3 0.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Vps39_1 PF10366.4 EPS29941.1 - 0.031 14.2 0.8 0.065 13.2 0.1 1.8 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 TPR_2 PF07719.12 EPS29941.1 - 0.091 12.7 0.2 3.6 7.7 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat RXT2_N PF08595.6 EPS29941.1 - 1.1 9.0 6.2 2.3 7.9 4.3 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.7 EPS29941.1 - 2.7 7.1 14.4 4.2 6.5 10.0 1.2 1 0 0 1 1 1 0 NOA36 protein Daxx PF03344.10 EPS29941.1 - 3.9 5.8 13.0 7.5 4.9 9.0 1.3 1 0 0 1 1 1 0 Daxx Family DUF155 PF02582.9 EPS29942.1 - 1.5e-43 148.7 0.0 2.1e-43 148.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Ribonuclease_T2 PF00445.13 EPS29943.1 - 6.9e-45 152.9 0.3 6.9e-45 152.9 0.2 1.7 2 0 0 2 2 2 1 Ribonuclease T2 family DUF1792 PF08759.6 EPS29943.1 - 0.0073 15.9 0.1 0.012 15.1 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1792) GFO_IDH_MocA PF01408.17 EPS29944.1 - 8.7e-20 71.4 0.0 1.5e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EPS29944.1 - 0.00017 21.3 0.0 0.00032 20.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DUF1115 PF06544.7 EPS29945.1 - 2.4e-19 69.3 0.0 3.9e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) zf-H2C2_2 PF13465.1 EPS29946.1 - 6.2e-12 45.1 6.0 1.6e-05 24.9 0.5 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 EPS29946.1 - 1.2e-06 28.4 17.9 0.00054 20.1 1.9 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPS29946.1 - 0.00038 20.5 15.4 0.0035 17.5 0.6 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EPS29946.1 - 0.019 15.1 1.8 0.031 14.4 0.5 2.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EPS29946.1 - 0.43 10.5 12.0 0.32 10.9 0.1 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger Bunya_G2 PF03563.8 EPS29946.1 - 0.61 8.9 1.6 0.85 8.4 1.1 1.2 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 zf-met PF12874.2 EPS29946.1 - 8 6.8 6.3 1.1 9.6 0.4 2.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type ubiquitin PF00240.18 EPS29947.1 - 1.5e-34 117.2 0.9 2.8e-34 116.3 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 EPS29947.1 - 5.1e-28 96.6 1.9 9.3e-28 95.7 1.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 EPS29947.1 - 6.1e-20 70.6 0.7 1e-19 69.9 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EPS29947.1 - 9.9e-06 25.7 0.4 4e-05 23.7 0.1 2.1 2 1 0 2 2 2 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EPS29947.1 - 0.00012 21.8 0.0 0.00017 21.2 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EPS29947.1 - 0.0012 18.6 0.6 0.0026 17.6 0.4 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EPS29947.1 - 0.0042 17.2 0.4 0.0057 16.8 0.3 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain IBR PF01485.16 EPS29947.1 - 0.018 14.8 0.4 0.029 14.2 0.3 1.4 1 0 0 1 1 1 0 IBR domain DUF2870 PF11069.3 EPS29947.1 - 0.06 13.3 0.6 0.14 12.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 EPS29947.1 - 0.16 10.2 2.3 4.9 5.3 0.1 2.1 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain Glyco_hydro_18 PF00704.23 EPS29948.1 - 3.9e-91 306.0 0.1 5.1e-91 305.6 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Proteasome PF00227.21 EPS29950.1 - 1.1e-49 168.3 0.2 1.5e-49 167.9 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EPS29950.1 - 5.7e-13 47.9 0.3 9e-13 47.2 0.2 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF2373 PF10180.4 EPS29951.1 - 9.2e-20 69.9 0.1 2.1e-19 68.7 0.1 1.7 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) MIP-T3 PF10243.4 EPS29951.1 - 0.0017 16.8 23.4 0.0017 16.8 16.2 2.1 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 DUF605 PF04652.11 EPS29951.1 - 2.1 7.6 39.9 0.079 12.3 9.1 2.2 2 0 0 2 2 2 0 Vta1 like Spc97_Spc98 PF04130.8 EPS29952.1 - 1.1e-121 406.7 0.0 1.5e-121 406.3 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family Aft1_HRA PF11786.3 EPS29953.1 - 1e-29 102.5 11.8 1e-29 102.5 8.2 3.2 3 0 0 3 3 3 1 Aft1 HRA domain Aft1_OSA PF11785.3 EPS29953.1 - 1.6e-21 76.5 7.6 1.6e-21 76.5 5.3 3.9 3 1 0 3 3 3 1 Aft1 osmotic stress response (OSM) domain Aft1_HRR PF11787.3 EPS29953.1 - 4.7e-18 66.0 5.6 4.7e-18 66.0 3.9 3.2 3 1 0 3 3 3 1 Aft1 HRR domain bZIP_1 PF00170.16 EPS29953.1 - 2.9e-13 49.5 4.7 5.3e-13 48.7 3.3 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EPS29953.1 - 4.2e-06 26.4 5.4 8.7e-06 25.4 3.7 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EPS29953.1 - 0.0022 18.2 2.1 0.0022 18.2 1.4 1.8 2 0 0 2 2 2 1 bZIP Maf transcription factor KIAA1328 PF15369.1 EPS29953.1 - 4.5 6.9 11.4 0.48 10.1 4.8 1.6 2 0 0 2 2 2 0 Uncharacterised protein KIAA1328 TFIIA PF03153.8 EPS29953.1 - 6.2 6.6 19.4 11 5.8 13.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cg6151-P PF10233.4 EPS29954.1 - 4.2e-40 136.2 13.5 5e-40 135.9 9.4 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P PRA1 PF03208.14 EPS29954.1 - 0.1 11.9 9.7 0.14 11.5 6.7 1.1 1 0 0 1 1 1 0 PRA1 family protein PEMT PF04191.8 EPS29954.1 - 0.44 10.6 9.0 1.5 8.9 0.6 2.1 1 1 1 2 2 2 0 Phospholipid methyltransferase TMEM220 PF15071.1 EPS29954.1 - 0.96 9.9 6.7 2.6 8.5 0.2 2.1 2 0 0 2 2 2 0 Transmembrane family 220, helix AgrB PF04647.10 EPS29954.1 - 1.6 7.7 10.6 2.2 7.3 7.4 1.1 1 0 0 1 1 1 0 Accessory gene regulator B DUF4149 PF13664.1 EPS29954.1 - 2 8.5 8.8 0.28 11.2 1.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) DUF4353 PF14262.1 EPS29955.1 - 0.003 16.8 0.0 0.0032 16.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4353) DUF3210 PF11489.3 EPS29956.1 - 3.8e-234 779.5 71.5 3.8e-234 779.5 49.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3210) ATP_sub_h PF10775.4 EPS29957.1 - 3e-27 94.1 1.2 4.5e-27 93.5 0.8 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 EPS29957.1 - 0.016 15.1 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 AIF-MLS PF14962.1 EPS29957.1 - 0.055 13.1 5.3 0.069 12.7 3.7 1.2 1 0 0 1 1 1 0 Mitochondria Localisation Sequence TFIIB PF00382.14 EPS29958.1 - 2.6e-36 123.2 0.0 9.7e-19 66.9 0.1 2.2 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EPS29958.1 - 1.5e-09 36.9 1.0 1.5e-09 36.9 0.7 1.7 2 0 0 2 2 2 1 TFIIB zinc-binding Cyclin_N PF00134.18 EPS29958.1 - 0.00071 19.1 0.0 0.74 9.3 0.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain HTH_23 PF13384.1 EPS29958.1 - 0.003 17.1 0.0 0.0093 15.5 0.0 1.8 1 0 0 1 1 1 1 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EPS29958.1 - 0.021 14.3 0.0 0.046 13.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 GerE PF00196.14 EPS29958.1 - 0.071 12.4 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family RAG2_PHD PF13341.1 EPS29959.1 - 0.092 12.7 0.2 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 RAG2 PHD domain DUF1765 PF08578.5 EPS29960.1 - 2.5e-44 150.3 2.4 2.5e-44 150.3 1.6 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1765) TPP_enzyme_N PF02776.13 EPS29961.1 - 2.1e-35 121.7 0.2 3.3e-35 121.0 0.2 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EPS29961.1 - 7e-20 71.1 0.0 1.5e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EPS29961.1 - 3e-16 59.3 1.6 1.9e-14 53.5 0.0 3.3 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 EPS29961.1 - 0.12 11.3 0.0 0.21 10.4 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Zn_clus PF00172.13 EPS29962.1 - 7.1e-06 25.8 10.2 1.3e-05 24.9 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EPS29962.1 - 0.00022 20.2 0.3 0.00083 18.3 0.0 2.0 1 1 1 2 2 2 1 Fungal specific transcription factor domain But2 PF09792.4 EPS29963.1 - 2.1e-58 196.1 3.4 3.7e-58 195.3 2.3 1.4 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain MFS_1 PF07690.11 EPS29964.1 - 3.3e-31 108.3 39.9 3.3e-31 108.3 27.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Cutinase PF01083.17 EPS29965.1 - 8.8e-45 152.6 2.8 8.8e-45 152.6 1.9 1.6 2 0 0 2 2 2 1 Cutinase Abhydrolase_2 PF02230.11 EPS29965.1 - 0.0049 16.3 0.1 0.0084 15.5 0.0 1.4 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 EPS29965.1 - 0.0052 16.3 0.0 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold PE-PPE PF08237.6 EPS29965.1 - 0.0062 15.9 0.3 0.012 15.0 0.2 1.4 1 0 0 1 1 1 1 PE-PPE domain Thioesterase PF00975.15 EPS29965.1 - 0.083 13.1 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain TFR_dimer PF04253.10 EPS29966.1 - 9.6e-33 112.4 0.1 1.7e-32 111.5 0.1 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EPS29966.1 - 5.3e-13 49.1 0.0 1.6e-12 47.4 0.0 1.9 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EPS29966.1 - 1.8e-08 33.9 0.0 3.4e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 EPS29966.1 - 0.0014 18.1 0.0 0.0027 17.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DIM1 PF02966.11 EPS29967.1 - 1e-70 235.3 0.3 1.2e-70 235.2 0.2 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 EPS29967.1 - 0.014 15.0 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Translin PF01997.11 EPS29968.1 - 4.3e-52 176.6 0.0 5e-52 176.4 0.0 1.0 1 0 0 1 1 1 1 Translin family FRQ PF09421.5 EPS29968.1 - 0.073 10.8 0.0 0.097 10.4 0.0 1.1 1 0 0 1 1 1 0 Frequency clock protein GMP_synt_C PF00958.17 EPS29968.1 - 0.078 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 GMP synthase C terminal domain GSHPx PF00255.14 EPS29969.1 - 1.2e-37 127.5 0.0 1.6e-37 127.1 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 EPS29969.1 - 0.0015 18.1 0.0 0.0022 17.6 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family SCO1-SenC PF02630.9 EPS29969.1 - 0.045 13.3 0.0 0.13 11.9 0.0 1.6 2 0 0 2 2 2 0 SCO1/SenC Pcc1 PF09341.5 EPS29970.1 - 3.4e-25 87.8 0.0 5e-25 87.3 0.0 1.3 1 0 0 1 1 1 1 Transcription factor Pcc1 SGS PF05002.10 EPS29970.1 - 0.029 14.1 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 SGS domain DSPn PF14671.1 EPS29972.1 - 3e-45 153.6 0.0 1.1e-41 142.1 0.0 3.2 3 0 0 3 3 3 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 EPS29972.1 - 6.5e-16 58.1 0.0 2.8e-15 56.0 0.0 2.0 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EPS29972.1 - 6.1e-06 25.7 0.0 1.5e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase LptE PF04390.7 EPS29972.1 - 0.043 13.5 0.5 0.083 12.6 0.3 1.4 1 0 0 1 1 1 0 Lipopolysaccharide-assembly Y_phosphatase3 PF13350.1 EPS29972.1 - 0.22 11.7 1.3 0.46 10.7 0.0 2.0 2 0 0 2 2 2 0 Tyrosine phosphatase family Fungal_trans_2 PF11951.3 EPS29973.1 - 6.7e-05 21.6 0.5 9.7e-05 21.1 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_6 PF12697.2 EPS29975.1 - 4.2e-34 118.4 0.3 5.4e-34 118.0 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPS29975.1 - 2.4e-19 69.8 0.1 3e-17 62.9 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPS29975.1 - 5.5e-14 52.1 0.5 1.3e-13 50.9 0.3 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EPS29975.1 - 5.3e-06 26.1 0.0 9.3e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 EPS29975.1 - 9.5e-06 24.2 0.0 1.4e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Ndr family PGAP1 PF07819.8 EPS29975.1 - 0.00059 19.4 0.2 0.0011 18.5 0.0 1.4 2 0 0 2 2 2 1 PGAP1-like protein DUF915 PF06028.6 EPS29975.1 - 0.00064 18.8 0.1 0.00089 18.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) DUF2424 PF10340.4 EPS29975.1 - 0.0022 16.7 0.1 0.0052 15.4 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Eno-Rase_NADH_b PF12242.3 EPS29975.1 - 0.0027 17.4 0.0 0.0071 16.1 0.0 1.7 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF676 PF05057.9 EPS29975.1 - 0.0043 16.3 0.0 0.007 15.6 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_3 PF07859.8 EPS29975.1 - 0.0095 15.5 0.1 0.035 13.6 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 EPS29975.1 - 0.019 13.8 0.0 0.13 11.1 0.0 2.2 2 1 0 2 2 2 0 Chlorophyllase enzyme Chlorophyllase PF07224.6 EPS29975.1 - 0.022 13.5 0.0 0.082 11.6 0.0 1.9 2 1 0 2 2 2 0 Chlorophyllase Esterase PF00756.15 EPS29975.1 - 0.024 14.0 0.0 0.036 13.5 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.20 EPS29975.1 - 0.044 13.3 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) DUF2305 PF10230.4 EPS29975.1 - 0.09 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DLH PF01738.13 EPS29975.1 - 0.11 11.7 0.7 9.6 5.4 0.1 3.1 2 1 0 2 2 2 0 Dienelactone hydrolase family DUF900 PF05990.7 EPS29975.1 - 0.12 11.7 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Ser_hydrolase PF06821.8 EPS29975.1 - 0.15 11.6 0.0 4.1 6.9 0.0 2.4 1 1 1 2 2 2 0 Serine hydrolase Pro_CA PF00484.14 EPS29975.1 - 0.16 11.9 0.0 0.4 10.6 0.0 1.5 1 1 0 1 1 1 0 Carbonic anhydrase DUF1057 PF06342.7 EPS29975.1 - 0.19 10.5 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Fungal_trans PF04082.13 EPS29977.1 - 4.1e-10 38.9 0.1 7.1e-10 38.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS29977.1 - 7.4e-06 25.7 11.2 1.5e-05 24.7 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-RING_2 PF13639.1 EPS29978.1 - 6.4e-13 48.3 8.1 9.3e-13 47.7 5.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EPS29978.1 - 3.8e-08 32.8 4.6 5.8e-08 32.2 3.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPS29978.1 - 7.7e-08 32.2 4.7 1.3e-07 31.4 3.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPS29978.1 - 2.5e-05 23.9 7.2 4e-05 23.2 5.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EPS29978.1 - 6e-05 23.0 7.7 0.00013 21.9 5.4 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EPS29978.1 - 0.00023 20.7 1.8 0.00057 19.5 0.8 1.9 1 1 0 1 1 1 1 RING-type zinc-finger SKG6 PF08693.5 EPS29978.1 - 0.00039 19.6 0.1 0.00065 18.9 0.0 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain zf-C3HC4_3 PF13920.1 EPS29978.1 - 0.0012 18.4 5.7 0.0023 17.5 3.9 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 EPS29978.1 - 0.0086 16.1 6.7 0.016 15.2 4.7 1.5 1 0 0 1 1 1 1 RING-variant domain Zn_Tnp_IS1595 PF12760.2 EPS29978.1 - 0.011 15.5 4.1 0.082 12.7 0.5 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Mid2 PF04478.7 EPS29978.1 - 0.012 14.9 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor zf-RING_4 PF14570.1 EPS29978.1 - 0.018 14.6 5.0 0.03 13.9 3.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-HYPF PF07503.7 EPS29978.1 - 0.022 14.1 2.2 0.24 10.8 0.3 2.4 2 0 0 2 2 2 0 HypF finger zf-Apc11 PF12861.2 EPS29978.1 - 0.03 14.1 4.3 0.054 13.3 2.9 1.4 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EPS29978.1 - 0.046 13.5 6.0 0.62 9.9 1.4 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING PhnA_Zn_Ribbon PF08274.7 EPS29978.1 - 0.07 12.9 1.4 0.98 9.2 0.1 2.3 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Rax2 PF12768.2 EPS29978.1 - 0.11 11.7 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity Baculo_RING PF05883.6 EPS29978.1 - 0.26 11.0 1.5 0.46 10.3 1.0 1.4 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain FANCL_C PF11793.3 EPS29978.1 - 0.47 10.4 8.1 4.4 7.3 5.6 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.3 EPS29978.1 - 0.53 9.8 2.9 0.86 9.1 2.0 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.1 EPS29978.1 - 0.74 9.3 10.3 1 8.9 4.0 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 PHD PF00628.24 EPS29978.1 - 0.77 9.5 7.2 1.8 8.3 5.0 1.7 1 1 0 1 1 1 0 PHD-finger Elf1 PF05129.8 EPS29978.1 - 1.1 8.9 4.4 3.1 7.5 0.3 2.3 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Prok-RING_1 PF14446.1 EPS29978.1 - 1.3 8.7 7.6 4.7 7.0 5.2 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 XPA_N PF01286.13 EPS29978.1 - 9.5 5.9 6.8 1.6 8.4 0.5 2.2 2 0 0 2 2 2 0 XPA protein N-terminal zf-MIZ PF02891.15 EPS29978.1 - 10 5.7 7.7 36 3.9 5.4 2.0 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger Pap_E4 PF02711.9 EPS29979.1 - 0.88 10.4 9.3 8.2 7.3 6.5 2.1 1 1 0 1 1 1 0 E4 protein Homeobox PF00046.24 EPS29981.1 - 5.9e-15 54.6 3.4 1.3e-14 53.5 2.4 1.6 1 0 0 1 1 1 1 Homeobox domain Uma2 PF05685.7 EPS29982.1 - 0.0018 17.6 0.0 0.0027 17.1 0.0 1.3 1 1 0 1 1 1 1 Putative restriction endonuclease Amino_oxidase PF01593.19 EPS29983.1 - 3.5e-43 148.3 0.6 3.5e-26 92.2 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EPS29983.1 - 3.1e-14 52.7 1.5 7.6e-14 51.4 1.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EPS29983.1 - 1.2e-05 25.6 0.4 2e-05 24.8 0.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPS29983.1 - 0.00041 20.4 0.8 0.00069 19.7 0.6 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EPS29983.1 - 0.00061 18.7 0.0 0.00088 18.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EPS29983.1 - 0.0042 16.2 0.4 0.0063 15.6 0.3 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EPS29983.1 - 0.005 15.7 0.6 0.0072 15.2 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EPS29983.1 - 0.0081 14.6 0.5 0.012 14.1 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 EPS29983.1 - 0.015 14.3 0.9 0.025 13.6 0.6 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 EPS29983.1 - 0.031 14.1 0.3 0.2 11.5 0.4 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EPS29983.1 - 0.09 12.4 0.2 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 EPS29983.1 - 0.18 11.6 1.1 0.73 9.5 0.4 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.17 EPS29983.1 - 0.38 9.5 1.3 0.54 9.0 0.9 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pol_alpha_B_N PF08418.5 EPS29984.1 - 0.39 10.2 4.8 0.64 9.5 3.4 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF2235 PF09994.4 EPS29985.1 - 5.7e-113 376.9 0.1 8e-113 376.4 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) An_peroxidase PF03098.10 EPS29986.1 - 2.8e-94 316.3 0.0 8.6e-92 308.2 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase GHL5 PF14872.1 EPS29986.1 - 0.14 9.9 0.0 0.22 9.2 0.0 1.2 1 0 0 1 1 1 0 Hypothetical glycoside hydrolase 5 p450 PF00067.17 EPS29986.1 - 0.2 10.1 0.0 1.3 7.4 0.0 2.0 2 0 0 2 2 2 0 Cytochrome P450 DUF2462 PF09495.5 EPS29986.1 - 1.9 9.2 5.9 4.5 8.0 4.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2462) Hexapep PF00132.19 EPS29987.1 - 7.2e-09 34.7 9.4 3.4e-05 23.1 1.3 4.4 3 1 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EPS29987.1 - 4e-06 26.2 0.3 4e-06 26.2 0.2 2.7 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase Glycos_transf_1 PF00534.15 EPS29988.1 - 1.2e-18 67.1 0.0 3.3e-18 65.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EPS29988.1 - 7.5e-08 32.6 0.0 2e-07 31.2 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EPS29988.1 - 3.9e-06 27.0 0.0 8e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Ribosomal_S14 PF00253.16 EPS29989.1 - 7.8e-18 63.6 0.8 1.2e-17 63.0 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e Synaphin PF05835.7 EPS29989.1 - 0.063 13.4 0.1 0.065 13.3 0.1 1.2 1 0 0 1 1 1 0 Synaphin protein Arb2 PF09757.4 EPS29990.1 - 2e-26 92.5 0.0 3e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Arb2 domain DJ-1_PfpI PF01965.19 EPS29991.1 - 2.3e-09 36.8 0.0 2.7e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EPS29991.1 - 2.2e-08 33.5 0.0 2.8e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Putative amidotransferase Prefoldin PF02996.12 EPS29992.1 - 2.4e-29 101.4 0.3 3e-29 101.1 0.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 EPS29992.1 - 0.0005 19.7 0.2 0.0013 18.4 0.0 1.7 1 1 0 1 1 1 1 Prefoldin subunit HR1 PF02185.11 EPS29992.1 - 0.0019 17.8 0.2 0.0049 16.5 0.0 1.7 2 0 0 2 2 2 1 Hr1 repeat MAD PF05557.8 EPS29992.1 - 0.0044 15.1 0.1 0.0081 14.3 0.1 1.3 1 0 0 1 1 1 1 Mitotic checkpoint protein DUF1128 PF06569.6 EPS29992.1 - 0.015 14.9 0.0 0.045 13.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1128) DUF4201 PF13870.1 EPS29992.1 - 0.018 14.4 0.5 0.088 12.2 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Vma12 PF11712.3 EPS29993.1 - 7.5e-36 122.9 0.0 1.2e-35 122.2 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase PsbN PF02468.10 EPS29993.1 - 0.083 12.5 0.2 0.21 11.2 0.1 1.7 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) Amidohydro_1 PF01979.15 EPS29994.1 - 7.5e-21 75.1 0.1 3.2e-18 66.4 0.0 3.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EPS29994.1 - 3.2e-20 73.2 0.5 1.2e-19 71.4 0.4 1.8 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EPS29994.1 - 7.6e-09 35.2 0.1 1.8e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EPS29994.1 - 6.8e-07 28.8 0.0 0.0011 18.3 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Glyco_hydro_26 PF02156.10 EPS29994.1 - 0.17 11.3 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 26 GRAM PF02893.15 EPS29996.1 - 1.2e-30 104.8 1.5 7e-18 63.9 0.0 3.6 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.15 EPS29996.1 - 3e-22 78.8 0.0 6.6e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.24 EPS29996.1 - 2.4e-14 53.4 0.0 3e-13 49.8 0.0 2.7 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 EPS29996.1 - 3.4e-07 30.4 0.2 1.6e-06 28.3 0.1 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 EPS29996.1 - 1.2e-05 25.2 0.0 4.2e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.1 EPS29996.1 - 0.00058 19.6 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 PH domain UDPGT PF00201.13 EPS29996.1 - 0.018 13.6 0.1 0.037 12.5 0.1 1.5 1 1 0 1 1 1 0 UDP-glucoronosyl and UDP-glucosyl transferase RNA_polI_A34 PF08208.6 EPS29997.1 - 5e-41 140.5 17.7 5e-41 140.5 12.3 2.2 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 Serglycin PF04360.7 EPS29997.1 - 2.5 7.8 7.6 4.7 6.9 5.3 1.4 1 0 0 1 1 1 0 Serglycin Clp1 PF06807.9 EPS29998.1 - 8.4e-07 28.9 0.0 0.04 13.6 0.0 2.3 2 0 0 2 2 2 2 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EPS29998.1 - 0.0017 18.0 0.0 0.0088 15.7 0.0 2.3 2 1 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EPS29998.1 - 0.0022 17.8 0.3 0.014 15.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EPS29998.1 - 0.0032 18.2 1.0 0.018 15.8 0.0 2.6 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 EPS29998.1 - 0.049 13.0 0.0 0.13 11.6 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family Med3 PF11593.3 EPS29998.1 - 0.092 11.9 2.9 0.12 11.5 2.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Prenylcys_lyase PF07156.9 EPS30000.1 - 2.7e-36 125.2 0.0 1.2e-24 86.8 0.0 2.3 2 1 0 2 2 2 2 Prenylcysteine lyase NAD_binding_8 PF13450.1 EPS30000.1 - 1e-12 47.8 0.1 2.5e-12 46.6 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EPS30000.1 - 2.9e-12 46.3 0.0 5.1e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 EPS30000.1 - 0.00019 20.4 1.1 0.0019 17.1 0.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EPS30000.1 - 0.002 17.9 0.1 0.0055 16.4 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EPS30000.1 - 0.021 14.8 0.0 0.23 11.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPS30000.1 - 0.034 14.0 0.0 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPS30000.1 - 0.058 13.8 0.7 3.7 8.0 0.2 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PDCD2_C PF04194.8 EPS30001.1 - 1.5e-54 184.0 0.0 4.2e-54 182.5 0.0 1.7 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain A2L_zn_ribbon PF08792.5 EPS30001.1 - 0.13 11.7 0.4 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain APH PF01636.18 EPS30002.1 - 6.9e-08 32.5 0.2 2.3e-07 30.8 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPS30002.1 - 7.2e-05 22.4 0.2 0.00013 21.6 0.1 1.4 1 1 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 EPS30002.1 - 0.031 13.4 0.1 0.094 11.8 0.0 1.7 2 1 0 2 2 2 0 Protein kinase domain PCI_Csn8 PF10075.4 EPS30003.1 - 5.4e-46 155.9 0.1 7.4e-46 155.4 0.1 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EPS30003.1 - 1.3e-24 86.8 0.3 1.7e-24 86.5 0.2 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Folliculin PF11704.3 EPS30004.1 - 1.4e-45 154.9 0.0 1.8e-45 154.5 0.0 1.2 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport SGT1 PF07093.6 EPS30007.1 - 1.3e-148 496.0 29.8 3.1e-147 491.5 20.7 2.0 1 1 0 1 1 1 1 SGT1 protein DUF965 PF06135.7 EPS30007.1 - 0.14 12.1 0.0 1.3 9.1 0.0 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF965) Microtub_assoc PF07989.6 EPS30008.1 - 4.3e-25 87.3 6.9 4.3e-25 87.3 4.8 10.8 9 3 4 14 14 14 1 Microtubule associated PACT_coil_coil PF10495.4 EPS30008.1 - 4.5e-24 84.1 1.3 4.5e-24 84.1 0.9 2.5 2 0 0 2 2 2 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Tropomyosin_1 PF12718.2 EPS30008.1 - 0.0095 15.7 13.9 0.0095 15.7 9.6 11.5 2 2 10 12 12 12 3 Tropomyosin like AAA_13 PF13166.1 EPS30008.1 - 0.18 10.1 111.2 0.0073 14.8 15.8 5.2 1 1 3 5 5 5 0 AAA domain Reo_sigmaC PF04582.7 EPS30008.1 - 0.73 8.9 45.8 0.64 9.1 0.4 6.9 2 2 5 8 8 8 0 Reovirus sigma C capsid protein AAA PF00004.24 EPS30009.1 - 4.6e-42 143.3 0.0 8.7e-42 142.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EPS30009.1 - 2.2e-29 101.1 0.0 1.1e-28 98.9 0.0 2.2 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 EPS30009.1 - 1.7e-23 82.2 1.9 1.7e-23 82.2 1.3 2.4 3 0 0 3 3 2 1 MIT (microtubule interacting and transport) domain AAA_17 PF13207.1 EPS30009.1 - 8.6e-07 29.8 0.0 8.7e-06 26.5 0.0 2.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EPS30009.1 - 7.1e-06 25.2 0.0 1.3e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EPS30009.1 - 1.1e-05 25.5 0.1 0.0013 18.8 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EPS30009.1 - 2.5e-05 24.0 0.0 0.00016 21.4 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EPS30009.1 - 2.6e-05 23.7 0.0 5.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 EPS30009.1 - 2.9e-05 23.5 0.1 0.21 10.9 0.1 3.3 2 1 1 3 3 3 2 AAA domain DUF815 PF05673.8 EPS30009.1 - 3e-05 23.0 0.0 0.0011 17.9 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 EPS30009.1 - 5.3e-05 23.2 0.1 0.00098 19.1 0.0 2.6 2 1 1 3 3 2 1 AAA ATPase domain RNA_helicase PF00910.17 EPS30009.1 - 5.4e-05 23.3 0.0 0.01 15.9 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_14 PF13173.1 EPS30009.1 - 7.5e-05 22.6 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EPS30009.1 - 0.00014 20.6 0.0 0.00024 19.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_2 PF07724.9 EPS30009.1 - 0.00035 20.5 0.0 0.0082 16.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EPS30009.1 - 0.00046 20.0 0.0 0.0012 18.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EPS30009.1 - 0.0057 16.2 0.2 0.033 13.7 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 EPS30009.1 - 0.0065 16.7 0.1 0.023 14.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EPS30009.1 - 0.0082 15.8 0.3 0.3 10.7 0.0 2.7 2 1 1 3 3 3 1 Archaeal ATPase Mg_chelatase PF01078.16 EPS30009.1 - 0.012 14.7 0.0 0.059 12.5 0.0 2.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI USP8_dimer PF08969.6 EPS30009.1 - 0.014 15.3 3.0 0.033 14.1 2.0 1.7 1 0 0 1 1 1 0 USP8 dimerisation domain AAA_19 PF13245.1 EPS30009.1 - 0.019 14.7 0.0 0.068 12.9 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 EPS30009.1 - 0.02 14.5 0.0 0.63 9.6 0.0 2.3 1 1 1 2 2 2 0 NACHT domain Torsin PF06309.6 EPS30009.1 - 0.021 14.7 0.1 0.079 12.8 0.0 1.9 2 0 0 2 2 2 0 Torsin EF-1_beta_acid PF10587.4 EPS30009.1 - 0.026 14.6 0.9 0.23 11.6 0.2 2.9 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region ResIII PF04851.10 EPS30009.1 - 0.028 14.2 0.0 0.062 13.1 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Zeta_toxin PF06414.7 EPS30009.1 - 0.031 13.3 0.0 0.15 11.1 0.0 2.1 1 1 1 2 2 2 0 Zeta toxin PhoH PF02562.11 EPS30009.1 - 0.042 13.0 0.0 0.094 11.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.12 EPS30009.1 - 0.05 12.4 0.0 0.086 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.1 EPS30009.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EPS30009.1 - 0.17 11.0 0.1 7.3 5.6 0.0 2.6 2 1 1 3 3 3 0 KaiC AAA_21 PF13304.1 EPS30009.1 - 0.18 11.7 0.2 2.3 8.1 0.1 2.3 1 1 0 1 1 1 0 AAA domain DUF4398 PF14346.1 EPS30009.1 - 0.65 10.0 3.3 0.49 10.4 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) Prefoldin_2 PF01920.15 EPS30010.1 - 2.8e-22 78.5 18.7 3.5e-22 78.1 13.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.1 EPS30010.1 - 0.00027 20.6 7.1 0.00041 20.0 4.9 1.3 1 0 0 1 1 1 1 Prefoldin subunit Spc7 PF08317.6 EPS30010.1 - 0.0009 17.9 15.2 0.001 17.7 10.6 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein AAA_27 PF13514.1 EPS30010.1 - 0.0013 16.5 13.2 0.0015 16.3 9.2 1.0 1 0 0 1 1 1 1 AAA domain DUF3727 PF12527.3 EPS30010.1 - 0.0043 17.1 5.8 0.45 10.6 0.5 2.6 1 1 2 3 3 3 2 Protein of unknown function (DUF3727) Spc24 PF08286.6 EPS30010.1 - 0.006 16.2 4.9 0.006 16.2 3.4 2.1 1 1 0 2 2 2 1 Spc24 subunit of Ndc80 Prefoldin PF02996.12 EPS30010.1 - 0.0091 15.6 17.1 0.037 13.6 11.8 1.9 1 1 0 1 1 1 1 Prefoldin subunit IncA PF04156.9 EPS30010.1 - 0.031 13.8 23.2 0.18 11.4 16.1 1.8 1 1 0 1 1 1 0 IncA protein COG5 PF10392.4 EPS30010.1 - 0.053 13.4 4.2 0.18 11.7 0.2 2.1 1 1 0 2 2 2 0 Golgi transport complex subunit 5 CENP-F_leu_zip PF10473.4 EPS30010.1 - 0.066 13.0 20.3 0.15 11.9 2.7 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.4 EPS30010.1 - 0.085 11.7 13.0 0.16 10.8 9.0 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TPR_MLP1_2 PF07926.7 EPS30010.1 - 0.098 12.3 17.5 0.49 10.1 3.4 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein FliJ PF02050.11 EPS30010.1 - 0.14 12.2 19.2 0.17 11.9 3.9 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein DUF4201 PF13870.1 EPS30010.1 - 0.14 11.5 13.3 0.91 8.9 3.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) HAP1_N PF04849.8 EPS30010.1 - 0.31 9.9 14.6 0.51 9.2 10.1 1.4 1 1 0 1 1 1 0 HAP1 N-terminal conserved region Myb_Cef PF11831.3 EPS30010.1 - 0.32 10.1 11.8 0.38 9.9 8.2 1.2 1 0 0 1 1 1 0 pre-mRNA splicing factor component XhlA PF10779.4 EPS30010.1 - 0.41 10.5 9.3 1.7 8.6 2.1 2.2 2 0 0 2 2 2 0 Haemolysin XhlA CENP-F_N PF10481.4 EPS30010.1 - 0.45 9.8 17.5 0.69 9.2 2.5 2.0 2 0 0 2 2 2 0 Cenp-F N-terminal domain DUF1192 PF06698.6 EPS30010.1 - 0.56 10.0 6.4 0.21 11.4 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DivIC PF04977.10 EPS30010.1 - 0.69 9.4 21.1 7.6 6.0 5.6 3.3 2 1 0 2 2 2 0 Septum formation initiator ERp29 PF07749.7 EPS30010.1 - 0.82 10.3 6.8 2.1 9.0 4.7 1.8 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain NPV_P10 PF05531.7 EPS30010.1 - 0.85 9.9 9.1 1.5 9.1 2.9 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.7 EPS30010.1 - 0.85 9.4 11.5 1.4 8.6 2.3 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Occludin_ELL PF07303.8 EPS30010.1 - 0.87 10.3 10.2 0.73 10.5 1.0 2.2 2 0 0 2 2 2 0 Occludin homology domain HalX PF08663.5 EPS30010.1 - 0.89 9.5 6.9 1.1 9.2 1.1 2.6 2 1 0 2 2 2 0 HalX domain DASH_Dam1 PF08653.5 EPS30010.1 - 0.93 9.2 3.3 1.3 8.8 0.7 2.3 3 0 0 3 3 2 0 DASH complex subunit Dam1 DASH_Dad3 PF08656.5 EPS30010.1 - 0.98 9.1 6.1 1.8 8.3 2.4 2.2 1 1 1 2 2 2 0 DASH complex subunit Dad3 Streptin-Immun PF11083.3 EPS30010.1 - 1 9.3 7.3 1.3 9.0 1.1 2.3 2 1 0 2 2 2 0 Lantibiotic streptin immunity protein FliD_N PF02465.13 EPS30010.1 - 1 9.7 9.4 0.39 11.1 0.5 2.4 2 1 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF4164 PF13747.1 EPS30010.1 - 1.3 9.2 9.7 3.5 7.8 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) COG2 PF06148.6 EPS30010.1 - 1.3 8.8 12.4 2 8.2 1.0 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 BLOC1_2 PF10046.4 EPS30010.1 - 1.7 8.8 11.8 0.82 9.8 2.3 2.6 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Sas10_Utp3 PF04000.10 EPS30010.1 - 1.7 8.8 7.2 0.47 10.6 2.0 2.0 1 1 1 2 2 2 0 Sas10/Utp3/C1D family DUF4200 PF13863.1 EPS30010.1 - 2 8.3 21.2 1 9.2 1.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) CorA PF01544.13 EPS30010.1 - 2.4 7.1 8.8 2.4 7.1 0.7 2.1 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF972 PF06156.8 EPS30010.1 - 2.4 8.5 14.5 1.3 9.3 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) ATG16 PF08614.6 EPS30010.1 - 2.5 7.9 16.6 12 5.6 11.5 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Siah-Interact_N PF09032.6 EPS30010.1 - 2.6 8.1 18.3 1.2 9.2 3.7 2.4 2 0 0 2 2 2 0 Siah interacting protein, N terminal Mnd1 PF03962.10 EPS30010.1 - 3 7.4 18.7 1.2 8.7 3.1 2.0 1 1 1 2 2 2 0 Mnd1 family DUF848 PF05852.6 EPS30010.1 - 3.1 7.6 13.7 1 9.1 1.7 2.1 1 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Tropomyosin_1 PF12718.2 EPS30010.1 - 3.1 7.6 19.1 0.68 9.7 3.5 2.1 2 0 0 2 2 2 0 Tropomyosin like TcdA_TcdB PF12919.2 EPS30010.1 - 3.7 5.9 9.6 4.7 5.5 6.7 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain DUF4140 PF13600.1 EPS30010.1 - 4.5 7.7 12.6 4.6 7.7 2.4 2.7 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) APG6 PF04111.7 EPS30010.1 - 6 5.8 19.2 1.9 7.4 6.1 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 Fmp27_WPPW PF10359.4 EPS30010.1 - 6.5 5.0 13.3 1.6 7.0 2.2 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Cep57_MT_bd PF06657.8 EPS30010.1 - 6.7 6.7 13.7 0.32 10.9 1.8 2.7 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Allexi_40kDa PF05549.6 EPS30010.1 - 6.7 5.9 6.6 5.4 6.2 0.4 1.9 1 1 1 2 2 2 0 Allexivirus 40kDa protein RP-C_C PF11800.3 EPS30010.1 - 7 6.2 10.1 1.1 8.8 1.0 1.9 1 1 0 2 2 2 0 Replication protein C C-terminal region bZIP_1 PF00170.16 EPS30010.1 - 8.3 6.4 9.8 7.2 6.6 1.0 2.8 2 1 0 2 2 2 0 bZIP transcription factor DUF904 PF06005.7 EPS30010.1 - 8.5 6.7 16.9 0.71 10.2 3.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Kinetocho_Slk19 PF12709.2 EPS30010.1 - 8.6 6.5 17.7 2.3 8.3 0.7 3.3 2 2 1 3 3 3 0 Central kinetochore-associated Metalloenzyme PF01676.13 EPS30011.1 - 1.5e-70 237.4 0.0 1.7e-70 237.3 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 EPS30011.1 - 2e-69 233.3 0.0 2.8e-69 232.8 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.17 EPS30011.1 - 4.4e-10 39.4 0.0 7.2e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EPS30011.1 - 5.5e-05 22.5 0.0 0.00011 21.5 0.0 1.5 1 1 0 1 1 1 1 Sulfatase SIS_2 PF13580.1 EPS30011.1 - 0.027 14.1 0.0 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 SIS domain Alk_phosphatase PF00245.15 EPS30011.1 - 0.047 12.3 0.0 0.091 11.4 0.0 1.4 1 0 0 1 1 1 0 Alkaline phosphatase Methyltransf_31 PF13847.1 EPS30011.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Med9 PF07544.8 EPS30012.1 - 2.8e-26 91.0 0.2 1.2e-25 89.0 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 SlyX PF04102.7 EPS30012.1 - 0.05 13.9 0.1 0.11 12.9 0.1 1.5 1 0 0 1 1 1 0 SlyX Med21 PF11221.3 EPS30012.1 - 0.49 10.3 3.8 1.1 9.2 2.6 1.6 1 1 0 1 1 1 0 Subunit 21 of Mediator complex SHMT PF00464.14 EPS30013.1 - 2e-209 694.9 0.0 2.3e-209 694.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 EPS30013.1 - 2.7e-07 29.8 0.0 5.5e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EPS30013.1 - 0.00029 19.6 0.0 0.0005 18.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EPS30013.1 - 0.00051 19.2 0.0 0.00075 18.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase AMMECR1 PF01871.12 EPS30014.1 - 6.6e-41 139.2 0.0 1.2e-40 138.3 0.0 1.4 1 0 0 1 1 1 1 AMMECR1 RAP1 PF07218.6 EPS30014.1 - 1.3 7.0 8.0 1.8 6.5 5.6 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pkinase PF00069.20 EPS30015.1 - 2.9e-70 236.4 0.0 3.7e-70 236.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS30015.1 - 1.3e-30 106.3 0.0 1.8e-30 105.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPS30015.1 - 9.4e-07 28.0 0.0 1.5e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EPS30015.1 - 0.00017 20.7 0.0 0.00032 19.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPS30015.1 - 0.00021 21.1 0.1 0.00034 20.4 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EPS30015.1 - 0.014 14.7 0.0 0.037 13.3 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL DUF1744 PF08490.7 EPS30016.1 - 6.7e-147 489.2 0.0 9.5e-147 488.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 EPS30016.1 - 2.6e-67 227.0 0.7 5.5e-67 225.9 0.5 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 EPS30016.1 - 7.6e-23 81.0 0.1 1.9e-22 79.7 0.1 1.6 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 EPS30016.1 - 3.9e-09 36.3 0.0 1.1e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EPS30016.1 - 3.3e-05 23.7 0.1 0.00014 21.6 0.0 2.2 2 1 0 2 2 2 1 RNase_H superfamily DUF3767 PF12597.3 EPS30017.1 - 6.7e-36 122.5 0.1 1.6e-35 121.3 0.0 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3767) Nop PF01798.13 EPS30020.1 - 8.4e-61 203.6 0.1 2.6e-60 202.0 0.0 1.9 2 0 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 EPS30020.1 - 7.8e-25 86.4 1.6 9.9e-25 86.1 0.2 1.9 2 0 0 2 2 2 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EPS30020.1 - 4.4e-21 74.8 0.0 4.4e-21 74.8 0.0 2.6 2 0 0 2 2 2 1 NOP5NT (NUC127) domain Cpn60_TCP1 PF00118.19 EPS30021.1 - 7.8e-148 493.0 0.2 8.9e-148 492.9 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family MOZ_SAS PF01853.13 EPS30022.1 - 8.6e-54 181.6 0.0 1.5e-50 171.0 0.0 2.1 2 0 0 2 2 2 2 MOZ/SAS family RRM_1 PF00076.17 EPS30023.1 - 3.3e-12 45.8 0.0 5.9e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS30023.1 - 6.8e-09 35.5 0.0 1.2e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS30023.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFR_dimer PF04253.10 EPS30023.1 - 0.069 12.7 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 Transferrin receptor-like dimerisation domain tRNA-synt_2 PF00152.15 EPS30024.1 - 9.3e-55 185.7 0.0 1.5e-54 185.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EPS30024.1 - 2.1e-06 27.4 0.0 3.4e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti-like PF12869.2 EPS30024.1 - 0.099 12.1 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 tRNA_anti-like Imm44 PF15584.1 EPS30024.1 - 0.1 12.4 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 44 DUF1652 PF07865.6 EPS30025.1 - 0.14 11.8 0.1 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1652) Polyketide_cyc2 PF10604.4 EPS30027.1 - 0.058 13.5 0.0 0.063 13.4 0.0 1.1 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Gti1_Pac2 PF09729.4 EPS30028.1 - 8.7e-50 168.8 0.7 1.2e-48 165.1 0.5 2.0 1 1 0 1 1 1 1 Gti1/Pac2 family CaMKII_AD PF08332.5 EPS30029.1 - 0.064 13.1 0.0 0.094 12.6 0.0 1.3 1 0 0 1 1 1 0 Calcium/calmodulin dependent protein kinase II Association DUF2442 PF10387.4 EPS30031.1 - 0.12 12.4 0.0 18 5.4 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2442) Fungal_trans_2 PF11951.3 EPS30032.1 - 5.5e-61 206.2 0.1 7.3e-61 205.8 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS30032.1 - 1.9e-09 37.2 10.4 3.1e-09 36.5 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.14 EPS30032.1 - 0.36 10.6 6.8 1.1 9.1 4.7 1.9 1 0 0 1 1 1 0 AT hook motif HpcH_HpaI PF03328.9 EPS30033.1 - 3.8e-37 127.3 0.0 4.5e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family VWA_2 PF13519.1 EPS30033.1 - 0.043 13.9 0.1 0.065 13.3 0.1 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain ABC_tran PF00005.22 EPS30034.1 - 8.6e-52 175.0 0.0 1.7e-25 89.8 0.0 2.3 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.19 EPS30034.1 - 1.3e-51 174.7 29.5 1.1e-29 103.1 7.5 2.3 2 0 0 2 2 2 2 ABC-2 type transporter AAA_21 PF13304.1 EPS30034.1 - 2.8e-18 66.8 0.4 3.7e-05 23.8 0.0 4.3 3 1 0 3 3 3 3 AAA domain AAA_16 PF13191.1 EPS30034.1 - 1.1e-09 38.5 0.1 0.0011 18.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EPS30034.1 - 3.3e-09 36.1 0.2 0.0024 17.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EPS30034.1 - 4.1e-09 36.1 0.0 0.0011 18.4 0.0 3.1 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.14 EPS30034.1 - 4.4e-08 32.6 0.4 0.0033 16.6 0.1 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EPS30034.1 - 5.3e-08 33.4 0.1 0.0017 18.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EPS30034.1 - 9.8e-07 28.2 1.8 0.021 14.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EPS30034.1 - 9.8e-07 28.9 0.2 0.019 15.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_15 PF13175.1 EPS30034.1 - 3.1e-06 26.5 0.0 1.3 7.9 0.0 3.9 4 0 0 4 4 4 1 AAA ATPase domain AAA_17 PF13207.1 EPS30034.1 - 6e-06 27.0 0.0 0.035 14.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EPS30034.1 - 8e-06 25.6 0.1 0.031 13.9 0.0 2.5 2 0 0 2 2 2 2 NACHT domain Arch_ATPase PF01637.13 EPS30034.1 - 1.1e-05 25.2 0.0 0.0056 16.4 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase AAA_10 PF12846.2 EPS30034.1 - 2.4e-05 23.9 3.0 0.12 11.7 0.0 2.5 2 0 0 2 2 2 2 AAA-like domain cobW PF02492.14 EPS30034.1 - 3.1e-05 23.5 0.7 0.084 12.3 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 EPS30034.1 - 9.7e-05 22.8 0.2 0.3 11.5 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein MobB PF03205.9 EPS30034.1 - 0.00019 21.1 0.3 0.25 11.0 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EPS30034.1 - 0.00021 21.2 3.3 0.13 12.1 0.0 3.2 3 1 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 EPS30034.1 - 0.00023 21.0 0.4 0.88 9.5 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.1 EPS30034.1 - 0.00034 20.6 1.1 0.25 11.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EPS30034.1 - 0.00037 20.6 0.1 0.44 10.7 0.0 2.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EPS30034.1 - 0.00061 18.7 0.1 0.043 12.7 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein RNA_helicase PF00910.17 EPS30034.1 - 0.00092 19.3 0.1 0.31 11.2 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_30 PF13604.1 EPS30034.1 - 0.00093 18.8 0.1 0.76 9.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EPS30034.1 - 0.00093 18.8 0.3 0.44 10.3 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain FtsK_SpoIIIE PF01580.13 EPS30034.1 - 0.0017 17.8 0.1 1.6 8.1 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_24 PF13479.1 EPS30034.1 - 0.0019 17.8 0.1 0.96 8.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EPS30034.1 - 0.0022 18.3 0.1 0.25 11.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EPS30034.1 - 0.0022 17.7 0.3 0.35 10.6 0.0 2.7 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EPS30034.1 - 0.0031 16.6 1.2 2.1 7.3 0.2 2.5 2 0 0 2 2 2 2 Zeta toxin PduV-EutP PF10662.4 EPS30034.1 - 0.0073 15.7 0.4 1.9 7.9 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.10 EPS30034.1 - 0.0082 15.8 0.4 2.8 7.6 0.0 3.1 3 0 0 3 3 3 1 NTPase ATP_bind_1 PF03029.12 EPS30034.1 - 0.0087 15.6 0.1 4.2 6.8 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SbcCD_C PF13558.1 EPS30034.1 - 0.013 15.3 0.8 7.4 6.5 0.0 3.7 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.20 EPS30034.1 - 0.014 14.9 0.0 4.5 6.7 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain UPF0079 PF02367.12 EPS30034.1 - 0.014 15.0 0.1 2.6 7.6 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Dynamin_N PF00350.18 EPS30034.1 - 0.019 14.8 1.7 0.9 9.3 0.1 2.3 2 0 0 2 2 2 0 Dynamin family AAA_14 PF13173.1 EPS30034.1 - 0.032 14.1 0.0 1.9 8.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.7 EPS30034.1 - 0.052 12.8 1.4 7.5 5.7 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein KAP_NTPase PF07693.9 EPS30034.1 - 0.053 12.5 0.0 5 6.0 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain SRPRB PF09439.5 EPS30034.1 - 0.087 12.0 0.3 6.4 5.9 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Septin PF00735.13 EPS30034.1 - 0.1 11.6 0.2 10 5.0 0.0 2.3 2 0 0 2 2 2 0 Septin PhoH PF02562.11 EPS30034.1 - 0.12 11.5 0.1 12 5.0 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein PRK PF00485.13 EPS30034.1 - 0.13 11.7 1.4 12 5.3 0.1 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_35 PF14516.1 EPS30034.1 - 0.25 9.9 0.4 3.3 6.2 0.0 2.1 2 0 0 2 2 2 0 AAA-like domain NB-ARC PF00931.17 EPS30034.1 - 0.26 10.1 0.1 2.9 6.6 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain DUF2075 PF09848.4 EPS30034.1 - 0.28 10.1 0.1 4.3 6.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF87 PF01935.12 EPS30034.1 - 0.32 10.7 0.6 18 5.0 0.7 2.7 3 0 0 3 3 2 0 Domain of unknown function DUF87 YTV PF07639.6 EPS30037.1 - 0.12 12.1 0.7 0.53 10.0 0.1 2.0 2 0 0 2 2 2 0 YTV Sec23_trunk PF04811.10 EPS30038.1 - 8.8e-52 175.8 0.0 3.4e-51 173.9 0.0 1.8 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EPS30038.1 - 3.6e-27 93.8 0.0 7.5e-27 92.7 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EPS30038.1 - 1.8e-18 66.8 0.0 3.2e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EPS30038.1 - 5.8e-16 57.7 4.9 1.2e-15 56.7 3.4 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EPS30038.1 - 3.7e-09 36.1 0.0 6.3e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Gelsolin repeat DUF1678 PF07913.6 EPS30038.1 - 0.17 11.4 0.0 0.48 9.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1678) AA_permease_2 PF13520.1 EPS30039.1 - 1.1e-51 175.8 45.2 1.3e-51 175.5 31.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPS30039.1 - 5.8e-22 77.6 40.4 7.8e-22 77.2 28.0 1.0 1 0 0 1 1 1 1 Amino acid permease Peptidase_M56 PF05569.6 EPS30039.1 - 1.9 7.3 7.1 0.2 10.5 1.4 1.9 2 0 0 2 2 2 0 BlaR1 peptidase M56 Fungal_trans PF04082.13 EPS30040.1 - 3.7e-22 78.4 0.1 7.3e-22 77.4 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2802 PF10975.3 EPS30040.1 - 0.03 14.0 2.0 0.17 11.6 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2802) HAD_2 PF13419.1 EPS30041.1 - 1.2e-30 107.0 0.1 1.4e-30 106.7 0.1 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EPS30041.1 - 0.018 14.9 0.0 0.38 10.6 0.0 2.3 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPS30041.1 - 0.065 13.6 0.0 0.21 11.9 0.0 1.9 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase AA_permease PF00324.16 EPS30042.1 - 7.6e-96 321.3 47.5 9.3e-96 321.0 32.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPS30042.1 - 2.7e-28 98.7 48.1 3.6e-28 98.2 33.4 1.1 1 0 0 1 1 1 1 Amino acid permease DAO PF01266.19 EPS30043.1 - 2.6e-55 187.8 0.1 3e-55 187.5 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EPS30043.1 - 2.1e-06 27.9 0.3 0.0001 22.4 0.2 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPS30043.1 - 1.3e-05 25.1 0.2 3.8e-05 23.6 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EPS30043.1 - 7.5e-05 22.5 0.5 0.0042 16.8 0.1 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.9 EPS30043.1 - 0.00038 19.0 0.3 0.41 9.0 0.0 2.1 1 1 0 2 2 2 2 HI0933-like protein Thi4 PF01946.12 EPS30043.1 - 0.00038 19.6 0.0 0.00086 18.4 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EPS30043.1 - 0.00053 20.3 0.5 0.2 12.0 0.1 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Strep_67kDa_ant PF06100.6 EPS30043.1 - 0.0099 14.2 0.1 0.026 12.8 0.1 1.6 2 0 0 2 2 2 1 Streptococcal 67 kDa myosin-cross-reactive antigen like family K_oxygenase PF13434.1 EPS30043.1 - 0.019 13.8 0.0 0.048 12.5 0.0 1.6 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EPS30043.1 - 0.023 14.5 1.2 0.056 13.3 0.8 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Malic_M PF03949.10 EPS30043.1 - 0.031 13.8 0.1 0.095 12.2 0.0 1.7 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain Shikimate_DH PF01488.15 EPS30043.1 - 0.052 13.6 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 EPS30043.1 - 0.056 12.2 1.5 0.096 11.5 0.6 1.6 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.7 EPS30043.1 - 0.11 11.3 0.1 0.19 10.5 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Frigida PF07899.6 EPS30043.1 - 0.19 10.4 0.0 0.27 9.9 0.0 1.1 1 0 0 1 1 1 0 Frigida-like protein CPSF100_C PF13299.1 EPS30044.1 - 4.2e-42 144.0 0.4 1.2e-41 142.5 0.0 2.0 2 0 0 2 2 2 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 EPS30044.1 - 2.2e-28 98.6 0.0 2.1e-27 95.5 0.0 2.4 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.7 EPS30044.1 - 0.0058 16.4 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 EPS30044.1 - 0.017 14.7 0.1 0.062 12.9 0.0 1.9 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily Pyridoxal_deC PF00282.14 EPS30044.1 - 0.11 10.8 0.0 0.2 10.0 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Frag1 PF10277.4 EPS30046.1 - 8.6e-43 146.3 14.2 1.7e-42 145.3 5.2 2.6 2 0 0 2 2 2 2 Frag1/DRAM/Sfk1 family DUF3918 PF13056.1 EPS30046.1 - 0.095 12.0 0.7 0.34 10.2 0.5 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) U3_assoc_6 PF08640.6 EPS30047.1 - 2.1e-28 97.8 1.1 5.2e-28 96.6 0.7 1.6 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.5 EPS30047.1 - 0.01 14.7 0.2 0.016 14.0 0.1 1.3 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 EPS30047.1 - 0.023 15.3 0.6 16 6.4 0.0 3.8 3 2 1 4 4 4 0 Tetratricopeptide repeat Suf PF05843.9 EPS30047.1 - 0.74 9.4 6.4 4.4 6.9 0.5 3.1 3 1 0 3 3 3 0 Suppressor of forked protein (Suf) RF-1 PF00472.15 EPS30048.1 - 5.7e-12 45.4 0.6 9.2e-12 44.7 0.4 1.3 1 0 0 1 1 1 1 RF-1 domain KBP_C PF12309.3 EPS30048.1 - 0.066 12.1 1.0 0.089 11.7 0.7 1.1 1 0 0 1 1 1 0 KIF-1 binding protein C terminal RRM_1 PF00076.17 EPS30049.1 - 3.3e-09 36.2 0.0 5.3e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS30049.1 - 2.5e-06 27.3 0.0 6.6e-06 26.0 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS30049.1 - 0.0016 18.2 0.1 0.0028 17.4 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) COX6B PF02297.12 EPS30050.1 - 3.1e-23 81.5 4.5 4.2e-23 81.1 3.1 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 EPS30050.1 - 0.0017 18.3 1.2 0.0025 17.8 0.8 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Prolamin_like PF05617.6 EPS30050.1 - 0.0061 16.6 0.2 0.0079 16.2 0.2 1.3 1 0 0 1 1 1 1 Prolamin-like Ax_dynein_light PF10211.4 EPS30050.1 - 0.02 14.7 2.5 0.022 14.5 1.8 1.0 1 0 0 1 1 1 0 Axonemal dynein light chain PP-binding_2 PF14573.1 EPS30050.1 - 0.033 14.2 0.0 0.046 13.7 0.0 1.2 1 0 0 1 1 1 0 Acyl-carrier XH PF03469.9 EPS30050.1 - 0.067 12.8 2.9 0.092 12.4 2.0 1.1 1 0 0 1 1 1 0 XH domain V-ATPase_G PF03179.10 EPS30050.1 - 0.62 10.3 5.6 0.81 10.0 3.9 1.2 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit SYS1 PF09801.4 EPS30051.1 - 4.6e-52 175.8 7.1 5.4e-52 175.6 5.0 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Amidase PF01425.16 EPS30052.1 - 7.9e-109 364.4 0.0 1e-108 364.0 0.0 1.1 1 0 0 1 1 1 1 Amidase Aldolase_II PF00596.16 EPS30053.1 - 5.3e-45 153.2 0.2 7e-45 152.8 0.1 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF2478 PF10649.4 EPS30053.1 - 0.043 13.1 0.1 0.088 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2478) COG5 PF10392.4 EPS30054.1 - 2.1e-39 134.5 0.3 2.1e-39 134.5 0.2 2.9 4 0 0 4 4 4 1 Golgi transport complex subunit 5 zf-H2C2_2 PF13465.1 EPS30056.1 - 6.9e-06 26.1 4.0 6.9e-06 26.1 2.8 2.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 EPS30056.1 - 6.7e-05 22.9 13.2 0.009 16.3 0.9 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPS30056.1 - 0.00032 20.8 16.7 0.0043 17.2 1.2 3.2 4 0 0 4 4 4 2 C2H2-type zinc finger DUF883 PF05957.8 EPS30057.1 - 0.00028 21.2 4.8 0.00085 19.6 3.1 2.0 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 EPS30057.1 - 0.00065 19.2 2.1 0.0015 18.0 1.5 1.6 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF3552 PF12072.3 EPS30057.1 - 0.0069 15.6 0.7 0.0082 15.3 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) AIF-MLS PF14962.1 EPS30057.1 - 0.087 12.4 0.8 0.12 12.0 0.6 1.2 1 0 0 1 1 1 0 Mitochondria Localisation Sequence ATP-synt_B PF00430.13 EPS30057.1 - 0.1 12.4 7.5 0.15 11.8 5.2 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) KfrA_N PF11740.3 EPS30057.1 - 0.12 12.8 1.7 0.11 12.9 0.6 1.4 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term Myosin_tail_1 PF01576.14 EPS30057.1 - 0.19 9.3 7.3 0.23 9.1 5.0 1.0 1 0 0 1 1 1 0 Myosin tail DUF1423 PF07227.6 EPS30057.1 - 0.21 10.2 2.3 0.24 9.9 1.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) LEA_4 PF02987.11 EPS30057.1 - 2.9 7.8 8.3 27 4.7 0.5 3.4 1 1 1 2 2 2 0 Late embryogenesis abundant protein MutS_V PF00488.16 EPS30059.1 - 2.5e-95 318.3 0.2 6.4e-95 317.0 0.0 1.7 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 EPS30059.1 - 5.7e-41 140.5 0.7 1.2e-40 139.5 0.5 1.6 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 EPS30059.1 - 4.3e-17 62.4 0.5 2.7e-16 59.8 0.0 2.4 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 EPS30059.1 - 1.5e-16 60.3 0.6 1.5e-16 60.3 0.4 2.6 3 0 0 3 3 3 1 MutS family domain IV MutS_I PF01624.15 EPS30059.1 - 2.3e-15 56.5 0.0 1.7e-14 53.8 0.0 2.4 2 0 0 2 2 2 1 MutS domain I Gpi1 PF05024.10 EPS30060.1 - 8.7e-63 211.4 9.0 1.6e-62 210.5 6.3 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) UPF0203 PF05254.7 EPS30061.1 - 1.1e-29 102.0 3.5 1.3e-29 101.8 2.4 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) Cmc1 PF08583.5 EPS30061.1 - 0.00033 20.3 3.4 0.069 12.9 0.0 2.1 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.8 EPS30061.1 - 0.00047 20.1 1.6 0.001 19.0 1.1 1.5 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) UCR_hinge PF02320.11 EPS30061.1 - 0.23 11.3 3.0 0.99 9.3 2.1 1.8 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein COX6B PF02297.12 EPS30061.1 - 0.38 10.8 5.9 0.47 10.5 0.6 2.0 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb DNA_pol_A_exo1 PF01612.15 EPS30062.1 - 1.2e-39 135.5 0.3 1.9e-39 134.9 0.2 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 EPS30062.1 - 1.8e-26 92.2 0.1 4e-26 91.1 0.1 1.6 1 0 0 1 1 1 1 PMC2NT (NUC016) domain HRDC PF00570.18 EPS30062.1 - 8.4e-12 44.6 0.2 2.2e-11 43.3 0.0 1.9 2 0 0 2 2 2 1 HRDC domain tRNA-synt_1b PF00579.20 EPS30063.1 - 3.6e-17 62.4 0.0 1e-16 60.9 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Aminotran_4 PF01063.14 EPS30064.1 - 4.9e-35 121.0 0.0 6.3e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV TPR_11 PF13414.1 EPS30065.1 - 2.2e-51 171.3 21.1 1.2e-11 44.0 0.3 7.8 4 2 5 9 9 9 9 TPR repeat TPR_1 PF00515.23 EPS30065.1 - 1.9e-39 131.6 23.4 6.1e-07 28.7 0.0 11.6 10 1 1 11 11 11 8 Tetratricopeptide repeat TPR_2 PF07719.12 EPS30065.1 - 1e-36 121.8 24.6 1.8e-05 24.2 0.0 11.1 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_16 PF13432.1 EPS30065.1 - 9e-28 96.3 13.7 8.7e-07 29.4 0.2 6.8 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 EPS30065.1 - 1.8e-23 82.2 25.5 1.5e-07 31.2 0.6 7.5 3 1 4 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.1 EPS30065.1 - 2e-19 67.8 14.1 0.0026 17.4 0.1 8.8 8 1 1 9 9 8 4 Tetratricopeptide repeat TPR_17 PF13431.1 EPS30065.1 - 2e-17 61.8 9.1 0.11 12.7 0.0 9.1 10 0 0 10 10 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 EPS30065.1 - 9e-16 56.9 14.5 0.015 15.8 0.1 9.4 6 2 4 10 10 9 5 Tetratricopeptide repeat TPR_7 PF13176.1 EPS30065.1 - 3.8e-14 51.2 16.4 0.025 14.3 0.1 8.7 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_9 PF13371.1 EPS30065.1 - 4.4e-13 48.8 13.9 5.3e-05 22.9 0.1 6.9 4 2 4 8 8 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 EPS30065.1 - 1.5e-12 47.6 17.4 1.3e-05 25.4 0.7 6.5 5 1 1 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 EPS30065.1 - 4.9e-11 42.6 13.8 0.011 15.8 0.2 5.5 2 1 4 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EPS30065.1 - 0.00015 21.9 26.4 3.3 8.3 0.5 9.0 10 0 0 10 10 9 2 Tetratricopeptide repeat PPP4R2 PF09184.6 EPS30065.1 - 0.0012 18.4 4.6 0.79 9.2 2.6 2.3 2 0 0 2 2 2 2 PPP4R2 BLVR PF06375.6 EPS30065.1 - 0.0023 17.7 6.2 0.0047 16.7 4.3 1.5 1 0 0 1 1 1 1 Bovine leukaemia virus receptor (BLVR) SHNi-TPR PF10516.4 EPS30065.1 - 0.0043 16.2 9.9 0.41 9.9 0.0 4.7 5 0 0 5 5 4 2 SHNi-TPR DUF1510 PF07423.6 EPS30065.1 - 0.0089 15.4 8.5 0.016 14.5 5.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) MAS20 PF02064.10 EPS30065.1 - 0.013 15.4 2.4 13 5.7 0.1 4.1 3 1 0 4 4 4 0 MAS20 protein import receptor TPR_10 PF13374.1 EPS30065.1 - 0.017 15.0 10.9 2.5 8.1 0.3 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat SR-25 PF10500.4 EPS30065.1 - 0.086 12.2 17.1 0.15 11.4 11.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ycf1 PF05758.7 EPS30065.1 - 0.12 10.1 0.9 0.16 9.6 0.6 1.2 1 0 0 1 1 1 0 Ycf1 SID-1_RNA_chan PF13965.1 EPS30065.1 - 0.22 9.6 0.4 0.34 9.0 0.3 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 NARP1 PF12569.3 EPS30065.1 - 0.32 9.7 27.0 0.44 9.2 0.3 4.8 2 1 1 3 3 3 0 NMDA receptor-regulated protein 1 Apc5 PF12862.2 EPS30065.1 - 0.58 10.0 10.7 11 5.9 0.0 4.7 3 2 1 4 4 3 0 Anaphase-promoting complex subunit 5 Presenilin PF01080.12 EPS30065.1 - 1.4 7.6 3.4 2.3 6.9 2.4 1.2 1 0 0 1 1 1 0 Presenilin TPR_3 PF07720.7 EPS30065.1 - 3 7.7 17.4 5 7.0 0.0 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat FHA PF00498.21 EPS30066.1 - 9.4e-12 44.8 0.0 1.9e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 FHA domain SDA1 PF05285.7 EPS30066.1 - 4.6 6.4 12.9 7.4 5.7 6.5 2.3 2 1 0 2 2 2 0 SDA1 MFS_1 PF07690.11 EPS30067.1 - 1.8e-34 119.0 24.5 2.9e-34 118.3 17.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EPS30067.1 - 3e-05 22.4 3.0 5e-05 21.7 2.0 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.11 EPS30067.1 - 0.0021 16.8 0.4 0.0072 15.0 0.0 1.8 1 1 0 2 2 2 1 BT1 family PTR2 PF00854.16 EPS30067.1 - 0.0098 14.7 4.4 0.019 13.7 3.1 1.5 1 0 0 1 1 1 1 POT family DUF1056 PF06341.6 EPS30067.1 - 1.4 9.0 11.5 0.15 12.1 0.5 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1056) FAD_binding_3 PF01494.14 EPS30069.1 - 1.5e-20 73.5 0.0 6.6e-20 71.4 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EPS30069.1 - 9e-10 37.9 6.8 0.00052 19.0 0.0 2.5 2 1 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EPS30069.1 - 2e-06 28.1 0.9 0.0062 16.9 0.4 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EPS30069.1 - 2.5e-05 23.3 0.9 3.9e-05 22.6 0.6 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EPS30069.1 - 2.5e-05 22.9 2.4 0.0031 16.0 1.8 2.1 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.1 EPS30069.1 - 6.7e-05 22.8 0.6 0.0002 21.3 0.4 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EPS30069.1 - 7.2e-05 22.7 0.2 0.00024 21.0 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EPS30069.1 - 0.00038 19.4 0.1 0.00048 19.0 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 EPS30069.1 - 0.001 17.7 1.2 0.0013 17.4 0.1 1.5 2 0 0 2 2 2 1 Tryptophan halogenase FAD_oxidored PF12831.2 EPS30069.1 - 0.006 15.7 5.3 0.0098 15.0 3.7 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EPS30069.1 - 0.0069 15.4 0.0 0.015 14.3 0.0 1.6 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase 3HCDH_N PF02737.13 EPS30069.1 - 0.007 16.0 0.1 0.011 15.3 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 EPS30069.1 - 0.0079 16.2 0.0 0.016 15.2 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPS30069.1 - 0.016 14.3 0.7 0.025 13.6 0.5 1.3 1 0 0 1 1 1 0 Thi4 family SE PF08491.5 EPS30069.1 - 0.023 13.5 0.0 0.14 10.9 0.0 1.9 1 1 0 1 1 1 0 Squalene epoxidase AlaDh_PNT_C PF01262.16 EPS30069.1 - 0.054 13.0 0.1 0.087 12.3 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GST_N_3 PF13417.1 EPS30070.1 - 1e-09 38.4 0.0 2.1e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EPS30070.1 - 1.2e-07 31.6 0.0 2.1e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EPS30070.1 - 9.1e-07 28.7 0.0 1.7e-06 27.9 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EPS30070.1 - 1.4e-05 25.5 0.0 2.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EPS30070.1 - 2.7e-05 24.2 0.0 8.3e-05 22.6 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EPS30070.1 - 0.0004 20.2 0.0 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Fungal_trans PF04082.13 EPS30071.1 - 3.3e-16 58.9 1.6 3.3e-16 58.9 1.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS30071.1 - 1.6e-09 37.5 12.7 2.9e-09 36.7 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tmemb_cc2 PF10267.4 EPS30071.1 - 0.035 12.7 0.4 0.054 12.0 0.3 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Cupin_2 PF07883.6 EPS30072.1 - 1.5e-14 53.2 0.6 8.9e-08 31.5 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EPS30072.1 - 0.0003 20.1 0.2 0.014 14.7 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF861) AraC_binding PF02311.14 EPS30072.1 - 0.012 15.2 0.1 0.59 9.8 0.0 2.3 2 0 0 2 2 2 0 AraC-like ligand binding domain cNMP_binding PF00027.24 EPS30072.1 - 0.056 13.2 0.0 0.39 10.5 0.0 2.2 2 0 0 2 2 2 0 Cyclic nucleotide-binding domain CENP-C_C PF11699.3 EPS30072.1 - 0.057 13.3 0.2 0.31 11.0 0.1 2.0 2 0 0 2 2 2 0 Mif2/CENP-C like Cupin_1 PF00190.17 EPS30072.1 - 0.062 12.7 0.2 13 5.1 0.0 2.5 2 0 0 2 2 2 0 Cupin Cupin_4 PF08007.7 EPS30072.1 - 0.085 12.0 0.4 0.27 10.4 0.1 1.8 2 0 0 2 2 2 0 Cupin superfamily protein EutQ PF06249.7 EPS30072.1 - 0.086 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ DUF3500 PF12006.3 EPS30073.1 - 1.3e-109 365.9 0.0 1.5e-109 365.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) L_HGMIC_fpl PF10242.4 EPS30074.1 - 3.1e-05 24.0 5.1 6.5e-05 23.0 3.5 1.5 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein ABC2_membrane PF01061.19 EPS30074.1 - 0.049 12.7 5.1 0.16 11.1 1.9 2.0 2 0 0 2 2 2 0 ABC-2 type transporter Claudin_3 PF06653.6 EPS30074.1 - 0.1 12.3 8.6 0.48 10.1 5.9 2.0 1 1 0 1 1 1 0 Tight junction protein, Claudin-like SPC12 PF06645.8 EPS30074.1 - 0.33 10.8 0.1 0.33 10.8 0.1 2.9 4 0 0 4 4 4 0 Microsomal signal peptidase 12 kDa subunit (SPC12) RRM_1 PF00076.17 EPS30075.1 - 5.4e-48 160.5 0.0 1.1e-12 47.4 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS30075.1 - 1.4e-42 143.5 0.0 2.7e-10 40.0 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS30075.1 - 5.7e-22 77.3 0.0 1.5e-05 24.7 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPS30075.1 - 1.4e-08 34.3 0.0 0.13 12.0 0.0 4.1 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif Lsm_interact PF05391.6 EPS30075.1 - 0.0017 17.6 0.5 0.0058 16.0 0.3 1.9 1 0 0 1 1 1 1 Lsm interaction motif Nup35_RRM PF05172.8 EPS30075.1 - 0.016 14.9 0.0 0.16 11.7 0.0 2.6 2 1 1 3 3 3 0 Nup53/35/40-type RNA recognition motif Ribosomal_L22 PF00237.14 EPS30076.1 - 2.3e-17 62.8 0.1 6.4e-08 32.4 0.1 2.5 2 0 0 2 2 2 2 Ribosomal protein L22p/L17e His_Phos_1 PF00300.17 EPS30077.1 - 2.5e-19 69.8 0.0 3.4e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) GST_N_3 PF13417.1 EPS30079.1 - 4e-14 52.5 0.0 8.7e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EPS30079.1 - 6e-12 45.2 0.1 1.2e-11 44.2 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EPS30079.1 - 7.4e-12 45.0 0.0 1.6e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EPS30079.1 - 2.1e-11 43.7 0.0 5.1e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EPS30079.1 - 9.4e-11 41.5 0.0 1.5e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EPS30079.1 - 1.2e-07 32.0 0.1 2.6e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glyco_trans_1_2 PF13524.1 EPS30079.1 - 0.13 12.5 0.1 7 7.0 0.0 2.5 2 0 0 2 2 2 0 Glycosyl transferases group 1 MetRS-N PF09635.5 EPS30079.1 - 0.13 12.6 0.0 1 9.7 0.0 2.1 1 1 0 1 1 1 0 MetRS-N binding domain zf-CCHC PF00098.18 EPS30080.1 - 1.4e-11 43.7 9.7 1.8e-05 24.4 0.4 2.3 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.24 EPS30080.1 - 1.7e-08 33.9 0.1 3.1e-08 33.1 0.1 1.4 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 EPS30080.1 - 7.3e-07 28.8 5.1 0.00059 19.5 1.9 2.5 1 1 1 2 2 2 2 Zinc knuckle KH_3 PF13014.1 EPS30080.1 - 1.2e-05 24.8 0.2 2.7e-05 23.6 0.1 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC_4 PF14392.1 EPS30080.1 - 0.0011 18.6 6.0 0.28 10.8 0.5 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_6 PF15288.1 EPS30080.1 - 0.0092 15.6 9.4 0.42 10.3 0.5 2.8 3 0 0 3 3 3 2 Zinc knuckle eIF3g PF12353.3 EPS30080.1 - 2.4 8.1 8.5 4.7 7.1 1.0 3.1 2 1 1 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G HCO3_cotransp PF00955.16 EPS30081.1 - 5.2e-67 226.6 10.8 5e-41 140.9 2.3 2.1 1 1 1 2 2 2 2 HCO3- transporter family TMEM171 PF15471.1 EPS30081.1 - 7.4 5.2 6.3 11 4.6 4.4 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 DEAD PF00270.24 EPS30082.1 - 1.2e-41 142.0 0.0 1.9e-41 141.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPS30082.1 - 6.4e-27 93.2 0.1 1.9e-26 91.7 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EPS30082.1 - 0.00033 19.5 0.0 0.00047 19.0 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EPS30082.1 - 0.00036 20.4 0.0 0.0009 19.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1793 PF08760.6 EPS30084.1 - 2.3e-73 245.6 0.2 4.9e-73 244.5 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) Arf PF00025.16 EPS30084.1 - 0.14 11.4 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family Stm1_N PF09598.5 EPS30085.1 - 5.4e-16 59.0 7.0 5.4e-16 59.0 4.9 5.3 3 1 0 3 3 3 1 Stm1 bZIP_1 PF00170.16 EPS30086.1 - 0.00015 21.6 10.3 0.00026 20.8 6.9 1.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EPS30086.1 - 0.024 14.4 9.9 0.024 14.4 6.9 1.7 2 0 0 2 2 2 0 Basic region leucine zipper DUF4407 PF14362.1 EPS30086.1 - 0.049 12.5 2.7 0.28 10.1 2.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.5 EPS30086.1 - 0.05 13.7 2.2 0.078 13.0 1.6 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family GvpL_GvpF PF06386.6 EPS30086.1 - 0.75 9.3 4.4 1.2 8.6 3.0 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Pex19 PF04614.7 EPS30087.1 - 5.1e-70 235.9 3.3 1.1e-69 234.7 2.3 1.6 1 1 0 1 1 1 1 Pex19 protein family EspB PF05802.6 EPS30087.1 - 0.11 11.3 1.7 0.16 10.8 1.2 1.1 1 0 0 1 1 1 0 Enterobacterial EspB protein T2SF PF00482.18 EPS30087.1 - 0.12 12.3 0.2 0.73 9.7 0.0 2.3 3 2 0 3 3 3 0 Type II secretion system (T2SS), protein F FliE PF02049.13 EPS30087.1 - 0.35 10.9 3.0 0.41 10.7 0.4 2.3 1 1 1 2 2 2 0 Flagellar hook-basal body complex protein FliE PGC7_Stella PF15549.1 EPS30088.1 - 0.084 12.8 1.2 0.16 11.9 0.9 1.5 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain Isochorismatase PF00857.15 EPS30089.1 - 1.4e-36 126.0 0.1 1.6e-36 125.8 0.1 1.0 1 0 0 1 1 1 1 Isochorismatase family Mid2 PF04478.7 EPS30090.1 - 4.6e-10 39.1 1.3 4.6e-10 39.1 0.9 2.7 1 1 0 2 2 2 1 Mid2 like cell wall stress sensor Rax2 PF12768.2 EPS30090.1 - 0.056 12.6 0.4 0.11 11.7 0.1 1.5 1 1 0 1 1 1 0 Cortical protein marker for cell polarity ORC6 PF05460.8 EPS30090.1 - 0.44 9.5 11.3 0.53 9.3 7.9 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SKG6 PF08693.5 EPS30090.1 - 4.6 6.6 7.9 0.19 11.0 0.4 2.5 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DUF2697 PF10906.3 EPS30092.1 - 1.5e-06 28.0 0.1 5.1e-06 26.3 0.0 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF2697) Fungal_trans_2 PF11951.3 EPS30093.1 - 3e-27 95.2 1.9 6.9e-27 94.0 1.3 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS30093.1 - 1.4e-06 28.0 8.0 2.7e-06 27.1 5.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 EPS30094.1 - 1e-66 224.7 0.0 1.4e-66 224.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS30094.1 - 3.2e-31 108.3 0.0 8.6e-31 106.9 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPS30094.1 - 9e-05 21.5 0.0 0.00018 20.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EPS30094.1 - 0.00072 18.6 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EPS30094.1 - 0.038 13.3 0.1 0.11 11.8 0.0 1.6 1 1 0 1 1 1 0 RIO1 family APH PF01636.18 EPS30094.1 - 0.055 13.1 0.1 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family APC_CDC26 PF10471.4 EPS30095.1 - 0.00012 22.7 5.6 0.00092 19.8 2.2 2.8 2 1 0 2 2 2 1 Anaphase-promoting complex APC subunit 1 NAD_binding_8 PF13450.1 EPS30096.1 - 3.3e-10 39.8 0.0 8.1e-10 38.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EPS30096.1 - 3e-05 24.1 0.0 9.7e-05 22.5 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EPS30096.1 - 3.5e-05 23.0 0.0 0.00032 19.9 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DUF1344 PF07076.6 EPS30096.1 - 0.011 15.2 0.1 0.19 11.3 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1344) FAD_binding_3 PF01494.14 EPS30096.1 - 0.011 14.7 0.1 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 EPS30096.1 - 0.013 15.3 0.0 0.033 14.0 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPS30096.1 - 0.019 14.0 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EPS30096.1 - 0.04 12.3 0.0 0.061 11.7 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.19 EPS30096.1 - 0.052 12.4 0.0 0.097 11.5 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase TrkA_N PF02254.13 EPS30096.1 - 0.066 13.2 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.1 EPS30096.1 - 0.073 12.8 0.4 0.6 9.8 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.2 EPS30096.1 - 0.097 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EPS30096.1 - 0.17 10.7 0.2 0.34 9.7 0.1 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein TPT PF03151.11 EPS30098.1 - 2.1e-27 95.6 14.4 2.1e-27 95.6 10.0 3.0 3 1 0 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 EPS30098.1 - 2e-05 23.6 23.8 0.00014 20.8 16.5 2.0 1 1 0 1 1 1 1 UAA transporter family DUF914 PF06027.7 EPS30098.1 - 0.018 13.8 14.1 0.061 12.1 9.7 1.8 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EPS30098.1 - 1.1 9.3 33.6 1.5 8.8 8.8 2.8 3 0 0 3 3 3 0 EamA-like transporter family TFIIB PF00382.14 EPS30100.1 - 4.2e-31 106.5 0.5 2.8e-16 59.0 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EPS30100.1 - 3.3e-25 88.1 0.1 7.4e-25 87.0 0.1 1.6 1 0 0 1 1 1 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 EPS30100.1 - 0.0002 20.6 2.2 0.00041 19.5 1.5 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 EPS30100.1 - 0.001 18.6 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain RRN7 PF11781.3 EPS30100.1 - 0.057 12.9 0.3 0.12 11.8 0.2 1.5 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 IBR PF01485.16 EPS30100.1 - 0.15 11.9 1.5 0.27 11.1 1.0 1.3 1 0 0 1 1 1 0 IBR domain YbaB_DNA_bd PF02575.11 EPS30100.1 - 0.16 11.8 0.7 10 6.0 0.0 2.8 2 1 0 2 2 2 0 YbaB/EbfC DNA-binding family E1-E2_ATPase PF00122.15 EPS30101.1 - 2.5e-54 183.7 0.0 3.3e-53 180.0 0.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EPS30101.1 - 2.7e-38 132.5 0.0 4.6e-38 131.7 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EPS30101.1 - 1.2e-28 99.0 1.0 1.1e-12 47.8 0.0 3.6 3 0 0 3 3 3 3 Heavy-metal-associated domain HAD PF12710.2 EPS30101.1 - 7e-18 65.4 0.0 1.3e-17 64.6 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EPS30101.1 - 2.9e-08 33.5 0.1 0.0013 18.3 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EPS30101.1 - 0.082 12.8 0.0 0.35 10.7 0.0 2.0 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase ERCC4 PF02732.10 EPS30102.1 - 1.5e-29 102.6 0.0 2.4e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 EPS30102.1 - 0.0002 21.4 0.0 0.0028 17.8 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain DUF4364 PF14277.1 EPS30102.1 - 0.00095 18.8 0.0 0.0019 17.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) Epimerase PF01370.16 EPS30103.1 - 3.9e-21 75.5 0.0 4.9e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPS30103.1 - 3e-13 49.1 0.0 3.4e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EPS30103.1 - 2.1e-08 33.3 0.1 0.00034 19.6 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 EPS30103.1 - 5.1e-08 33.1 0.0 7e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EPS30103.1 - 3e-07 30.5 0.0 3.7e-05 23.7 0.0 2.3 1 1 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EPS30103.1 - 3.3e-06 26.2 0.0 1e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain KR PF08659.5 EPS30103.1 - 0.00095 18.8 0.0 0.21 11.2 0.0 2.3 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EPS30103.1 - 0.0022 16.9 0.0 0.0058 15.5 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Ldh_1_N PF00056.18 EPS30103.1 - 0.012 15.4 0.0 0.018 14.8 0.0 1.4 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Fungal_trans PF04082.13 EPS30104.1 - 2.6e-07 29.8 0.6 6.1e-07 28.5 0.4 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS30104.1 - 2.7e-06 27.1 10.6 4.4e-06 26.5 7.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ChAPs PF09295.5 EPS30106.1 - 1.3e-156 521.3 0.0 1.7e-156 520.9 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 EPS30106.1 - 9.6e-08 31.5 0.9 0.0032 17.0 0.1 2.5 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EPS30106.1 - 4.3e-05 22.9 0.2 1.7 8.3 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EPS30106.1 - 4.8e-05 22.8 0.2 1.2 9.1 0.0 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EPS30106.1 - 5.6e-05 22.7 0.6 0.13 12.1 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EPS30106.1 - 0.00087 19.7 5.3 5.3 7.9 0.0 4.8 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 EPS30106.1 - 0.00093 19.4 0.6 2.5 8.5 0.0 2.8 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EPS30106.1 - 0.0016 18.3 1.4 8.7 6.3 0.0 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EPS30106.1 - 0.0017 18.4 0.1 1.3 9.2 0.0 3.2 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 EPS30106.1 - 0.0043 16.1 1.3 0.26 10.3 0.1 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EPS30106.1 - 0.0063 17.1 0.1 6.1 7.6 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EPS30106.1 - 0.019 14.7 2.1 16 5.5 0.0 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 EPS30107.1 - 4.1e-05 23.1 3.7 0.91 9.2 0.4 4.9 4 0 0 4 4 4 3 TPR repeat Kinesin PF00225.18 EPS30108.1 - 9.2e-61 205.3 0.0 1.3e-60 204.8 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain PspA_IM30 PF04012.7 EPS30108.1 - 0.012 15.0 3.2 0.89 8.8 0.0 2.3 2 0 0 2 2 2 0 PspA/IM30 family DUF837 PF05769.6 EPS30108.1 - 0.029 13.9 2.6 0.052 13.0 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF837) End3 PF12761.2 EPS30108.1 - 0.041 13.5 0.8 0.072 12.7 0.5 1.4 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 CENP-F_leu_zip PF10473.4 EPS30108.1 - 0.05 13.4 6.8 0.16 11.7 0.1 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_2 PF07716.10 EPS30108.1 - 0.12 12.1 5.9 0.045 13.5 1.7 2.2 2 0 0 2 2 2 0 Basic region leucine zipper IncA PF04156.9 EPS30108.1 - 6.9 6.2 11.3 4.7 6.7 2.0 2.2 1 1 1 2 2 2 0 IncA protein MFS_1 PF07690.11 EPS30109.1 - 2.5e-32 111.9 31.4 1.1e-31 109.8 21.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS30109.1 - 4.8e-15 55.0 21.7 7.7e-15 54.4 15.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter DUF1049 PF06305.6 EPS30109.1 - 0.023 14.1 0.8 0.42 10.1 0.0 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1049) Peptidase_S24 PF00717.18 EPS30110.1 - 5.5e-08 32.3 0.1 1.6e-07 30.8 0.0 1.6 1 1 1 2 2 2 1 Peptidase S24-like UQ_con PF00179.21 EPS30111.1 - 6.8e-40 135.7 0.0 7.7e-40 135.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EPS30111.1 - 9.3e-07 28.6 0.0 1.7e-06 27.7 0.0 1.3 1 1 0 1 1 1 1 Prokaryotic E2 family B HMG14_17 PF01101.13 EPS30112.1 - 1.1 9.9 4.6 1.5 9.5 3.2 1.3 1 0 0 1 1 1 0 HMG14 and HMG17 RabGAP-TBC PF00566.13 EPS30113.1 - 8.8e-39 133.1 0.0 1.7e-38 132.2 0.0 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Choline_transpo PF04515.7 EPS30114.1 - 2.1e-107 358.7 22.7 2.1e-107 358.7 15.8 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter DUF4191 PF13829.1 EPS30114.1 - 7.2 5.6 8.8 14 4.6 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4191) DUF863 PF05904.6 EPS30115.1 - 0.038 12.2 1.8 0.047 11.9 1.2 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF863) CFEM PF05730.6 EPS30115.1 - 0.055 13.3 10.7 0.061 13.1 5.3 2.1 2 0 0 2 2 2 0 CFEM domain Pkinase PF00069.20 EPS30116.1 - 2.7e-24 85.7 0.0 2.8e-17 62.7 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPS30116.1 - 9.9e-09 34.6 0.0 2.3e-06 26.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase BCS1_N PF08740.6 EPS30118.1 - 1.4e-54 184.5 0.3 1.9e-54 184.1 0.2 1.1 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EPS30118.1 - 3e-18 66.3 0.0 5.9e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EPS30118.1 - 5.8e-05 23.8 0.0 0.00013 22.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPS30118.1 - 0.0002 21.4 0.2 0.00084 19.3 0.1 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 EPS30118.1 - 0.00053 20.3 0.0 0.0017 18.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 EPS30118.1 - 0.00073 18.5 0.0 0.0013 17.6 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.1 EPS30118.1 - 0.0013 18.8 0.0 0.0055 16.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EPS30118.1 - 0.0016 17.9 0.0 0.0038 16.6 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EPS30118.1 - 0.0031 17.5 0.0 0.0049 16.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EPS30118.1 - 0.0062 16.4 0.0 0.015 15.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EPS30118.1 - 0.0067 16.1 0.0 0.023 14.3 0.0 2.0 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EPS30118.1 - 0.01 15.9 0.0 0.039 14.1 0.0 2.0 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.22 EPS30118.1 - 0.011 16.0 0.0 0.036 14.3 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.1 EPS30118.1 - 0.011 15.2 0.0 0.042 13.3 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_19 PF13245.1 EPS30118.1 - 0.031 14.0 0.0 0.31 10.8 0.0 2.8 2 0 0 2 2 2 0 Part of AAA domain KaiC PF06745.8 EPS30118.1 - 0.055 12.5 0.0 0.13 11.4 0.0 1.6 1 0 0 1 1 1 0 KaiC DUF258 PF03193.11 EPS30118.1 - 0.06 12.5 0.0 0.23 10.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 EPS30118.1 - 0.091 12.3 0.1 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EPS30118.1 - 0.1 13.0 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein AAA_11 PF13086.1 EPS30118.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EPS30118.1 - 0.2 11.3 0.0 0.64 9.6 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase Lactamase_B_2 PF12706.2 EPS30119.1 - 4.8e-39 133.9 0.1 6.1e-39 133.5 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EPS30119.1 - 1.1e-10 41.4 0.0 2.5e-09 37.0 0.0 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EPS30119.1 - 9.3e-08 31.9 1.9 5.5e-07 29.4 1.3 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Cpn60_TCP1 PF00118.19 EPS30120.1 - 8.1e-164 545.8 0.1 9.2e-164 545.6 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1168 PF06658.7 EPS30121.1 - 2.7e-44 150.1 10.4 3.9e-44 149.6 7.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) ATP-synt_E PF05680.7 EPS30121.1 - 3.8 7.5 8.1 7.4 6.5 5.6 1.4 1 0 0 1 1 1 0 ATP synthase E chain zf-PARP PF00645.13 EPS30122.1 - 1.3e-21 76.5 0.5 2.8e-21 75.5 0.3 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Sec31 PF11549.3 EPS30122.1 - 0.36 10.5 0.0 0.36 10.5 0.0 3.8 3 1 1 4 4 4 0 Protein transport protein SEC31 CDC27 PF09507.5 EPS30122.1 - 1.2 8.3 54.3 1.5 7.9 37.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF3712 PF12505.3 EPS30123.1 - 0.02 14.9 0.1 0.078 13.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3712) BTB PF00651.26 EPS30125.1 - 3.8e-06 26.8 0.0 9.2e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain B3_4 PF03483.12 EPS30125.1 - 0.051 13.0 0.1 7.7 5.9 0.0 2.2 2 0 0 2 2 2 0 B3/4 domain DUF3420 PF11900.3 EPS30126.1 - 0.034 14.2 3.3 18 5.5 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3420) DUF2752 PF10825.3 EPS30126.1 - 0.47 10.5 4.6 0.77 9.8 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) Pkinase_Tyr PF07714.12 EPS30129.1 - 0.00033 19.7 0.4 0.004 16.2 0.3 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EPS30129.1 - 0.0013 17.9 0.0 0.0025 17.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Glyco_hydro_18 PF00704.23 EPS30131.1 - 4.5e-52 177.6 0.1 1.7e-51 175.6 0.1 2.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LysM PF01476.15 EPS30131.1 - 3e-10 39.8 0.1 3.3e-05 23.6 0.0 2.8 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.14 EPS30131.1 - 0.00013 21.8 5.0 0.00013 21.8 3.5 3.8 3 0 0 3 3 3 1 Chitin recognition protein DUF3142 PF11340.3 EPS30131.1 - 0.005 16.5 0.0 0.0093 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3142) CFEM PF05730.6 EPS30132.1 - 0.00054 19.7 5.7 0.00054 19.7 4.0 2.8 2 0 0 2 2 2 1 CFEM domain Pkinase PF00069.20 EPS30133.1 - 6.9e-10 38.5 0.0 6.9e-08 31.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPS30133.1 - 1.9e-07 30.4 0.0 7.6e-07 28.4 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EPS30133.1 - 0.017 14.1 0.0 0.064 12.2 0.0 1.7 1 1 0 2 2 2 0 Kinase-like Glyco_hydro_72 PF03198.9 EPS30134.1 - 1.6e-98 329.6 0.4 2.3e-98 329.0 0.3 1.2 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 EPS30134.1 - 0.13 11.1 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Cu-oxidase_2 PF07731.9 EPS30135.1 - 0.099 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Multicopper oxidase hEGF PF12661.2 EPS30135.1 - 0.51 10.5 3.3 0.33 11.1 0.6 2.0 2 0 0 2 2 2 0 Human growth factor-like EGF Sds3 PF08598.6 EPS30140.1 - 3.4e-51 173.7 6.6 1.1e-50 172.0 4.6 1.8 1 1 0 1 1 1 1 Sds3-like Exonuc_VII_L PF02601.10 EPS30140.1 - 0.067 12.3 2.1 0.13 11.4 1.5 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Lipase_2 PF01674.13 EPS30140.1 - 0.084 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 2) CMD PF02627.15 EPS30144.1 - 0.0036 17.1 0.0 0.0062 16.3 0.0 1.4 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family TpcC PF12642.2 EPS30145.1 - 0.071 12.6 0.1 0.093 12.2 0.1 1.1 1 0 0 1 1 1 0 Conjugative transposon protein TcpC Aldose_epim PF01263.15 EPS30147.1 - 6.1e-46 156.8 0.5 8.1e-46 156.4 0.4 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase ACOX PF01756.14 EPS30148.1 - 3.3e-35 121.1 0.0 9e-35 119.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 EPS30148.1 - 2.3e-22 79.5 1.7 5.2e-22 78.4 1.2 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 EPS30148.1 - 7.2e-08 31.8 0.0 1.7e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EPS30148.1 - 0.024 14.7 0.8 0.093 12.8 0.5 2.0 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain AMP-binding PF00501.23 EPS30149.1 - 3.9e-52 177.0 0.0 4.7e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPS30149.1 - 1.9e-10 41.5 0.1 6.1e-10 39.9 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ECH PF00378.15 EPS30150.1 - 3.9e-23 81.8 0.0 4.3e-23 81.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Actin PF00022.14 EPS30151.1 - 2.3e-22 78.9 0.0 2e-14 52.8 0.0 3.3 3 1 0 3 3 3 3 Actin Peptidase_C26 PF07722.8 EPS30151.1 - 0.14 11.6 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase C26 XPG_I PF00867.13 EPS30152.1 - 1.3e-22 79.6 0.0 3.9e-22 78.1 0.0 1.9 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EPS30152.1 - 0.00013 22.1 0.0 0.00031 20.9 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain Peptidase_S28 PF05577.7 EPS30153.1 - 8e-50 169.6 3.4 1.6e-49 168.6 2.3 1.5 1 1 0 1 1 1 1 Serine carboxypeptidase S28 DEAD PF00270.24 EPS30154.1 - 3.8e-36 124.1 0.0 1.1e-35 122.6 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EPS30154.1 - 9.3e-21 73.1 0.0 1.8e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EPS30154.1 - 1.2e-19 69.9 0.0 3.6e-19 68.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPS30154.1 - 0.013 15.3 1.4 0.056 13.2 0.0 2.4 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EPS30154.1 - 0.069 13.2 1.0 0.37 10.9 0.0 2.4 2 1 0 2 2 2 0 AAA domain CTP_transf_1 PF01148.15 EPS30155.1 - 6.2e-18 65.3 3.1 7.8e-16 58.5 0.5 2.1 1 1 1 2 2 2 2 Cytidylyltransferase family TPPK_C PF12555.3 EPS30155.1 - 0.11 12.2 0.0 0.11 12.2 0.0 3.3 4 0 0 4 4 4 0 Thiamine pyrophosphokinase C terminal Ribosomal_S15 PF00312.17 EPS30157.1 - 2e-18 65.9 0.2 5.7e-18 64.4 0.2 1.8 1 0 0 1 1 1 1 Ribosomal protein S15 Toxin_52 PF15605.1 EPS30157.1 - 0.023 14.5 1.2 0.053 13.4 0.0 2.1 2 0 0 2 2 2 0 Putative toxin 52 Ribosomal_S2 PF00318.15 EPS30158.1 - 2.9e-43 147.5 0.0 1.6e-22 79.7 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 Ras PF00071.17 EPS30159.1 - 1.1e-16 60.6 0.0 2.6e-16 59.4 0.0 1.6 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EPS30159.1 - 2.6e-08 34.3 0.0 4.4e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPS30159.1 - 0.0011 18.2 0.0 0.016 14.4 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family ABC_tran PF00005.22 EPS30159.1 - 0.0041 17.4 0.0 0.0054 17.0 0.0 1.4 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 EPS30159.1 - 0.011 15.1 0.3 0.026 14.0 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.15 EPS30159.1 - 0.012 14.2 0.0 0.015 14.0 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit DUF258 PF03193.11 EPS30159.1 - 0.014 14.6 0.0 0.028 13.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 NACHT PF05729.7 EPS30159.1 - 0.014 15.1 0.1 0.027 14.1 0.1 1.5 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 EPS30159.1 - 0.02 14.9 0.4 0.046 13.6 0.2 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 EPS30159.1 - 0.028 14.5 0.0 0.046 13.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EPS30159.1 - 0.029 13.9 0.1 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 EPS30159.1 - 0.033 13.2 0.0 0.042 12.8 0.0 1.2 1 0 0 1 1 1 0 Septin MMR_HSR1 PF01926.18 EPS30159.1 - 0.034 14.0 0.0 0.082 12.8 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.17 EPS30159.1 - 0.042 14.0 0.1 0.14 12.3 0.0 1.8 1 1 0 1 1 1 0 RNA helicase PRK PF00485.13 EPS30159.1 - 0.07 12.6 0.0 0.092 12.2 0.0 1.3 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Rad17 PF03215.10 EPS30159.1 - 0.16 10.5 0.1 0.22 10.1 0.1 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein PseudoU_synth_1 PF01416.15 EPS30160.1 - 2.1e-27 95.6 0.0 2.6e-21 76.0 0.0 2.8 2 1 0 2 2 2 2 tRNA pseudouridine synthase ubiquitin PF00240.18 EPS30161.1 - 0.00021 20.6 0.0 0.00033 19.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.5 EPS30161.1 - 0.053 14.0 0.0 0.091 13.3 0.0 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD DUF1777 PF08648.7 EPS30161.1 - 2.4 7.8 37.7 3.8 7.2 26.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Pribosyl_synth PF14572.1 EPS30162.1 - 3.8e-39 134.3 2.6 1.6e-34 119.3 0.5 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EPS30162.1 - 1.4e-31 108.6 0.0 5.9e-31 106.6 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EPS30162.1 - 5.3e-11 42.3 0.2 1.4e-10 40.9 0.2 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EPS30162.1 - 0.00051 19.3 0.2 0.00085 18.5 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase vATP-synt_AC39 PF01992.11 EPS30163.1 - 1.1e-110 369.9 0.0 1.2e-110 369.8 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Nop PF01798.13 EPS30164.1 - 4.7e-55 185.0 1.0 8.7e-55 184.1 0.7 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EPS30164.1 - 1.1e-26 92.4 0.1 1.9e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EPS30164.1 - 4.7e-21 74.7 1.0 4.7e-21 74.7 0.7 2.4 2 0 0 2 2 2 1 NOP5NT (NUC127) domain HWE_HK PF07536.9 EPS30164.1 - 0.063 13.7 1.8 7.4 7.0 0.1 3.5 3 0 0 3 3 3 0 HWE histidine kinase RNA_pol_Rpb4 PF03874.11 EPS30165.1 - 3.3e-06 27.0 0.6 0.007 16.3 0.0 2.7 2 1 0 2 2 2 2 RNA polymerase Rpb4 FUSC-like PF12805.2 EPS30166.1 - 0.041 12.8 0.0 0.072 12.0 0.0 1.3 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS EBV-NA3 PF05009.7 EPS30167.1 - 0.13 11.4 0.3 2.3 7.3 0.5 2.1 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Band_7 PF01145.20 EPS30168.1 - 3.6e-28 98.6 3.0 6e-28 97.9 2.1 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Acetyltransf_1 PF00583.19 EPS30169.1 - 2.2e-07 30.8 0.0 4.1e-07 29.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPS30169.1 - 8.2e-07 29.1 0.0 1.8e-06 27.9 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPS30169.1 - 0.00039 20.5 0.0 0.00062 19.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPS30169.1 - 0.0018 18.1 0.0 0.0035 17.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPS30169.1 - 0.0068 16.1 0.0 0.025 14.3 0.0 1.9 1 1 0 1 1 1 1 FR47-like protein adh_short PF00106.20 EPS30171.1 - 5.4e-10 39.4 0.1 1e-09 38.5 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPS30171.1 - 0.00083 19.0 0.0 0.0051 16.4 0.0 1.9 1 1 0 1 1 1 1 KR domain F-box-like PF12937.2 EPS30172.1 - 4.6e-06 26.2 0.9 8.3e-06 25.4 0.0 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EPS30172.1 - 4.6e-05 22.9 0.0 0.0001 21.8 0.0 1.6 1 0 0 1 1 1 1 F-box domain CENP-L PF13092.1 EPS30173.1 - 7.2e-48 162.4 0.1 1.1e-47 161.7 0.1 1.3 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 Sulfate_transp PF00916.15 EPS30175.1 - 5.9e-52 176.3 9.7 8.1e-52 175.9 5.4 2.0 1 1 1 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EPS30175.1 - 5e-26 90.2 4.0 5e-26 90.2 2.8 2.8 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EPS30175.1 - 3.3e-17 61.9 0.0 5.4e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EPS30175.1 - 1.3e-05 25.0 0.0 3e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 STAS domain EIF_2_alpha PF07541.7 EPS30176.1 - 5.4e-39 132.4 0.2 1.5e-38 131.0 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EPS30176.1 - 2e-12 47.0 0.5 4.4e-12 45.9 0.4 1.6 1 0 0 1 1 1 1 S1 RNA binding domain PKD_channel PF08016.7 EPS30177.1 - 0.0018 16.8 21.2 0.0048 15.3 13.6 2.2 1 1 0 1 1 1 1 Polycystin cation channel Hydrolase PF00702.21 EPS30178.1 - 1.7e-23 84.1 0.0 2.1e-21 77.3 0.0 3.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EPS30178.1 - 1.6e-21 77.3 1.5 3.4e-21 76.2 1.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EPS30178.1 - 3.2e-21 75.4 0.0 1.1e-20 73.7 0.0 1.8 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.7 EPS30178.1 - 0.00018 21.1 0.1 0.0018 17.9 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPS30178.1 - 0.00044 20.1 0.0 0.0035 17.2 0.0 2.3 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit S6PP PF05116.8 EPS30178.1 - 0.12 11.6 0.5 0.4 9.9 0.0 2.1 3 0 0 3 3 3 0 Sucrose-6F-phosphate phosphohydrolase Aldo_ket_red PF00248.16 EPS30179.1 - 4.4e-50 170.0 0.0 5.5e-50 169.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 EPS30180.1 - 2.7e-14 52.6 0.0 3.9e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Kdo PF06293.9 EPS30181.1 - 1.3e-11 43.9 0.0 8.2e-11 41.3 0.0 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPS30181.1 - 1.5e-08 34.6 0.4 0.00029 20.6 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.20 EPS30181.1 - 3.9e-07 29.4 0.0 4.3e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS30181.1 - 0.0019 17.3 0.0 0.0025 16.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EPS30181.1 - 0.012 14.9 0.0 0.59 9.4 0.0 2.7 2 1 0 2 2 2 0 RIO1 family Choline_kinase PF01633.15 EPS30181.1 - 0.036 13.6 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.15 EPS30181.1 - 0.092 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase NAD_binding_6 PF08030.7 EPS30182.1 - 1.2e-18 67.4 0.0 2.3e-16 60.0 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EPS30182.1 - 3.3e-16 59.0 0.0 1.2e-15 57.2 0.0 1.9 1 1 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EPS30182.1 - 1.8e-14 53.9 16.2 5.7e-14 52.2 11.2 2.0 1 0 0 1 1 1 1 Ferric reductase like transmembrane component CLU PF13236.1 EPS30184.1 - 8.2e-80 267.3 0.0 2e-79 266.1 0.0 1.7 2 0 0 2 2 2 1 Clustered mitochondria eIF3_p135 PF12807.2 EPS30184.1 - 6.9e-55 185.5 0.0 8.3e-54 182.0 0.0 2.4 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.1 EPS30184.1 - 9.6e-28 96.1 0.2 2.7e-27 94.7 0.1 1.9 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.1 EPS30184.1 - 1.9e-23 82.1 5.4 7.4e-10 38.6 0.0 4.0 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_10 PF13374.1 EPS30184.1 - 8.4e-16 57.3 0.1 0.00014 21.6 0.0 4.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 EPS30184.1 - 2e-06 27.3 2.5 0.071 12.7 0.0 3.7 2 1 1 3 3 3 3 TPR repeat TPR_2 PF07719.12 EPS30184.1 - 4.5e-05 23.0 3.7 0.36 10.8 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EPS30184.1 - 0.0055 17.3 0.0 2.2 9.0 0.0 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EPS30184.1 - 0.012 15.2 1.9 1.2 9.1 0.3 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 EPS30184.1 - 0.016 15.3 2.0 1.2e+02 3.3 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF727 PF05303.7 EPS30184.1 - 0.03 14.1 0.0 0.13 12.0 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF727) Dicty_REP PF05086.7 EPS30184.1 - 0.72 7.5 1.4 1.3 6.6 1.0 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein AAA_16 PF13191.1 EPS30185.1 - 1.3e-05 25.2 1.9 0.00042 20.3 0.8 2.7 2 1 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 EPS30185.1 - 0.00024 20.8 0.1 0.00095 18.9 0.0 1.9 1 1 0 1 1 1 1 Archaeal ATPase AAA_25 PF13481.1 EPS30185.1 - 0.00086 18.7 0.0 0.0081 15.5 0.0 2.5 3 0 0 3 3 3 1 AAA domain ATP-synt_ab PF00006.20 EPS30185.1 - 0.02 14.3 0.0 0.79 9.1 0.0 2.4 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain KaiC PF06745.8 EPS30185.1 - 0.073 12.1 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.1 EPS30185.1 - 0.11 12.6 0.1 0.42 10.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain RTA1 PF04479.8 EPS30187.1 - 2.1e-51 174.5 4.9 2.8e-51 174.1 3.4 1.1 1 0 0 1 1 1 1 RTA1 like protein Deltaretro_Tax PF05599.6 EPS30187.1 - 0.11 12.8 0.1 2.1 8.7 0.0 2.6 3 0 0 3 3 3 0 Deltaretrovirus Tax protein XFP_N PF09364.5 EPS30188.1 - 2.9e-153 509.9 0.0 3.8e-153 509.5 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.10 EPS30188.1 - 9.9e-70 233.7 0.1 1.5e-69 233.1 0.0 1.3 1 0 0 1 1 1 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.5 EPS30188.1 - 2.7e-66 222.8 0.0 4.2e-66 222.2 0.0 1.3 1 0 0 1 1 1 1 XFP C-terminal domain TPP_enzyme_C PF02775.16 EPS30188.1 - 0.03 13.8 0.1 0.082 12.4 0.1 1.7 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SH3_2 PF07653.12 EPS30188.1 - 0.084 12.3 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain Acetate_kinase PF00871.12 EPS30189.1 - 3.8e-91 305.5 0.0 4.5e-91 305.2 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family DUF1464 PF07318.7 EPS30189.1 - 0.089 11.5 0.1 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) Ras PF00071.17 EPS30193.1 - 2e-56 189.8 0.0 2.6e-56 189.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPS30193.1 - 8.3e-21 74.6 0.0 1.2e-20 74.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPS30193.1 - 3e-14 52.6 0.0 4.6e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EPS30193.1 - 3.4e-06 26.3 0.0 3.8e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EPS30193.1 - 3.5e-05 23.3 0.0 8.6e-05 22.0 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EPS30193.1 - 0.0001 22.2 0.0 0.00018 21.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EPS30193.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 EPS30193.1 - 0.093 12.8 0.0 0.23 11.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain Ribosomal_S7e PF01251.13 EPS30194.1 - 8.6e-84 279.7 0.8 9.6e-84 279.5 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Dynactin_p62 PF05502.8 EPS30195.1 - 1.1e-189 631.2 0.0 1.4e-189 630.8 0.0 1.1 1 0 0 1 1 1 1 Dynactin p62 family Trm112p PF03966.11 EPS30195.1 - 0.091 13.1 1.5 8.4 6.8 0.0 3.2 3 0 0 3 3 3 0 Trm112p-like protein Mu-like_Com PF10122.4 EPS30195.1 - 0.87 8.6 6.3 1.2 8.2 0.9 2.7 2 0 0 2 2 2 0 Mu-like prophage protein Com Methyltransf_11 PF08241.7 EPS30196.1 - 2.1e-12 47.3 0.0 4.6e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPS30196.1 - 4.9e-09 36.5 0.0 9.7e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPS30196.1 - 6.6e-09 35.6 0.0 1.1e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPS30196.1 - 8.4e-07 28.6 0.0 1.8e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPS30196.1 - 0.00098 19.4 0.0 0.0029 17.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPS30196.1 - 0.0056 15.8 0.0 0.0094 15.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EPS30196.1 - 0.038 14.5 0.0 0.24 11.9 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain P16-Arc PF04699.9 EPS30197.1 - 3.9e-61 205.5 0.0 4.5e-61 205.3 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) 2-Hacid_dh_C PF02826.14 EPS30198.1 - 2.3e-39 134.3 0.0 3.1e-39 133.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EPS30198.1 - 6.9e-18 64.4 0.0 7.9e-18 64.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.16 EPS30198.1 - 0.041 13.7 0.0 0.75 9.6 0.0 2.7 2 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.1 EPS30198.1 - 0.12 12.6 0.0 0.48 10.7 0.0 2.0 2 0 0 2 2 2 0 XdhC Rossmann domain DUF500 PF04366.7 EPS30199.1 - 6.5e-37 125.7 0.1 1e-36 125.1 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) E1-E2_ATPase PF00122.15 EPS30200.1 - 6.1e-62 208.6 0.2 1.2e-61 207.6 0.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EPS30200.1 - 8.3e-48 162.3 8.7 8.3e-48 162.3 6.0 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EPS30200.1 - 2.6e-26 93.3 0.0 1e-25 91.4 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPS30200.1 - 7.1e-17 61.1 0.0 1.5e-16 60.1 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EPS30200.1 - 5.4e-12 46.2 0.0 1.2e-11 45.1 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EPS30200.1 - 1.6e-08 33.8 0.0 8.1e-08 31.6 0.0 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EPS30200.1 - 0.00015 21.3 0.0 0.0013 18.3 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Adeno_E3_CR2 PF02439.10 EPS30202.1 - 0.0012 18.3 0.1 0.0029 17.1 0.1 1.6 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Plasmodium_Vir PF05795.6 EPS30202.1 - 0.043 13.0 0.5 0.063 12.4 0.4 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SKG6 PF08693.5 EPS30202.1 - 0.094 12.0 0.1 0.29 10.4 0.1 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EB1 PF03271.12 EPS30204.1 - 8.1e-16 57.7 1.1 1.5e-15 56.9 0.7 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 EPS30204.1 - 5.1e-07 29.6 0.7 8e-07 29.0 0.5 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain WD40 PF00400.27 EPS30205.1 - 6.7e-45 149.4 9.5 4e-09 36.0 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.2 EPS30205.1 - 2.3e-08 33.6 0.1 4.9e-08 32.5 0.1 1.6 1 0 0 1 1 1 1 F-box-like PQQ_2 PF13360.1 EPS30205.1 - 0.00033 20.2 0.4 0.012 15.1 0.3 2.5 1 1 0 1 1 1 1 PQQ-like domain F-box PF00646.28 EPS30205.1 - 0.00036 20.0 0.0 0.00071 19.1 0.0 1.5 1 0 0 1 1 1 1 F-box domain PQQ PF01011.16 EPS30205.1 - 0.0019 17.6 0.1 3.7 7.2 0.0 3.2 3 0 0 3 3 3 2 PQQ enzyme repeat Nup160 PF11715.3 EPS30205.1 - 0.048 11.7 1.0 5.3 5.0 0.0 2.9 2 1 1 3 3 3 0 Nucleoporin Nup120/160 PQQ_3 PF13570.1 EPS30205.1 - 0.23 11.8 2.8 12 6.3 0.1 4.2 4 1 1 5 5 5 0 PQQ-like domain ADH_zinc_N PF00107.21 EPS30206.1 - 3e-17 62.3 0.0 8.7e-17 60.8 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPS30206.1 - 9.3e-16 57.5 6.5 6.1e-14 51.6 4.5 2.3 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.14 EPS30206.1 - 5.7e-05 22.3 0.1 9.9e-05 21.5 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 EPS30206.1 - 0.09 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DHDPS PF00701.17 EPS30207.1 - 3.2e-32 111.2 0.0 3.1e-23 81.7 0.0 2.0 2 0 0 2 2 2 2 Dihydrodipicolinate synthetase family GFO_IDH_MocA PF01408.17 EPS30208.1 - 5.2e-10 39.8 0.2 1.4e-09 38.5 0.1 1.9 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold PHD PF00628.24 EPS30209.1 - 1.6e-08 34.1 10.2 3e-08 33.2 7.0 1.5 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 EPS30209.1 - 0.00094 19.4 0.0 0.0018 18.5 0.0 1.5 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding zf-HC5HC2H PF13771.1 EPS30209.1 - 0.12 12.4 1.8 0.25 11.5 1.2 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING-like PF08746.6 EPS30209.1 - 1.8 8.6 5.6 3.1 7.8 3.9 1.4 1 0 0 1 1 1 0 RING-like domain RNase_T PF00929.19 EPS30210.1 - 0.0041 17.4 0.0 0.012 15.8 0.0 1.8 2 0 0 2 2 2 1 Exonuclease TENA_THI-4 PF03070.11 EPS30211.1 - 1.5e-14 54.2 0.0 6.1e-07 29.4 0.0 2.8 3 0 0 3 3 3 2 TENA/THI-4/PQQC family Fork_head PF00250.13 EPS30212.1 - 2e-37 127.0 1.6 3.7e-37 126.2 1.1 1.4 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EPS30212.1 - 4.9e-08 32.9 0.0 1.1e-07 31.8 0.0 1.7 1 0 0 1 1 1 1 FHA domain zf-C2H2 PF00096.21 EPS30213.1 - 3.2e-07 30.2 12.9 2.7e-05 24.2 1.9 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EPS30213.1 - 1.8e-05 24.8 3.3 1.8e-05 24.8 2.3 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EPS30213.1 - 0.00047 20.3 11.8 0.0014 18.8 0.5 3.5 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EPS30213.1 - 0.0011 19.0 0.7 0.0031 17.5 0.5 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 EPS30213.1 - 0.026 14.8 3.8 0.38 11.1 1.6 2.4 2 0 0 2 2 2 0 TRAF-type zinc finger 2OG-FeII_Oxy PF03171.15 EPS30214.1 - 2.4e-05 24.5 0.0 4.7e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EPS30214.1 - 5e-05 22.8 0.5 5e-05 22.8 0.3 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EPS30214.1 - 6.8e-05 23.3 0.1 0.00013 22.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.13 EPS30216.1 - 6.1e-30 103.9 0.0 1.7e-29 102.5 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS30216.1 - 9.6e-11 41.4 12.9 1.7e-10 40.6 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EPS30217.1 - 0.00037 19.3 1.4 0.00048 18.9 0.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS30218.1 - 1.6e-107 359.8 24.8 1.8e-107 359.7 17.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS30218.1 - 1e-28 100.0 37.0 3.8e-27 94.9 13.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily GlnD_UR_UTase PF08335.6 EPS30218.1 - 0.21 11.3 0.7 0.36 10.6 0.5 1.3 1 0 0 1 1 1 0 GlnD PII-uridylyltransferase Fungal_trans_2 PF11951.3 EPS30219.1 - 1.2e-05 24.0 0.3 2.2e-05 23.2 0.2 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Sigma70_r2 PF04542.9 EPS30219.1 - 0.0045 16.5 0.0 0.017 14.7 0.0 1.9 1 0 0 1 1 1 1 Sigma-70 region 2 APH PF01636.18 EPS30220.1 - 3.9e-07 30.0 0.0 5.8e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family PHD PF00628.24 EPS30221.1 - 2.8e-11 42.9 7.3 2.8e-11 42.9 5.1 2.2 2 0 0 2 2 2 1 PHD-finger APH PF01636.18 EPS30221.1 - 0.00019 21.2 0.0 0.00019 21.2 0.0 2.0 3 0 0 3 3 3 1 Phosphotransferase enzyme family ORC6 PF05460.8 EPS30221.1 - 0.61 9.1 9.9 1.3 8.0 6.9 1.5 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Meth_synt_2 PF01717.13 EPS30225.1 - 6.8e-14 51.5 0.0 1.6e-12 47.0 0.0 2.3 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EPS30225.1 - 0.1 11.8 0.1 1.2 8.3 0.0 2.5 3 0 0 3 3 3 0 Cobalamin-independent synthase, N-terminal domain DUF2945 PF11160.3 EPS30226.1 - 4.4e-22 77.6 1.0 4.9e-22 77.5 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2945) Arf PF00025.16 EPS30227.1 - 4.4e-71 237.7 0.2 5.1e-71 237.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EPS30227.1 - 3.7e-14 52.4 0.0 4.1e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EPS30227.1 - 6.8e-13 48.0 1.2 1.8e-09 36.7 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EPS30227.1 - 1.7e-12 46.9 0.1 2.2e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EPS30227.1 - 2.7e-10 39.8 0.0 3e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EPS30227.1 - 1e-07 32.4 0.0 1.6e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EPS30227.1 - 0.00011 22.1 0.1 0.00017 21.5 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EPS30227.1 - 0.00049 19.5 0.0 0.00091 18.7 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 EPS30227.1 - 0.014 14.5 0.2 0.022 13.8 0.1 1.6 1 1 0 1 1 1 0 6-phosphofructo-2-kinase FeoB_N PF02421.13 EPS30227.1 - 0.018 14.3 0.4 0.022 14.0 0.3 1.5 1 1 0 1 1 1 0 Ferrous iron transport protein B Ribosomal_S8 PF00410.14 EPS30229.1 - 2.2e-27 95.4 0.0 3.7e-27 94.7 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S8 3Beta_HSD PF01073.14 EPS30230.1 - 2.4e-57 193.7 0.0 2.8e-57 193.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EPS30230.1 - 7.4e-42 143.3 0.0 9.1e-42 143.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EPS30230.1 - 1.4e-19 70.0 0.0 1.9e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EPS30230.1 - 3e-19 68.9 0.0 6.1e-17 61.3 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EPS30230.1 - 5.5e-14 52.4 0.0 1e-13 51.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EPS30230.1 - 4.3e-13 49.6 0.0 5.9e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EPS30230.1 - 4.7e-09 35.5 0.0 1.6e-08 33.8 0.0 1.9 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 EPS30230.1 - 1.6e-08 34.3 0.0 3.7e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 EPS30230.1 - 0.00098 18.1 0.0 0.0013 17.7 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 EPS30230.1 - 0.0011 18.9 0.0 0.0027 17.6 0.0 1.7 2 0 0 2 2 1 1 TrkA-N domain NmrA PF05368.8 EPS30230.1 - 0.0091 15.2 0.0 0.022 14.0 0.0 1.6 1 1 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 EPS30230.1 - 0.022 15.0 0.0 0.039 14.2 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Iso_dh PF00180.15 EPS30233.1 - 8.9e-98 327.4 0.0 1.7e-97 326.5 0.0 1.4 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF1769 PF08588.5 EPS30234.1 - 1.3e-28 98.6 1.6 1.8e-28 98.2 0.1 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF1769) Reo_sigmaC PF04582.7 EPS30235.1 - 0.0031 16.7 2.4 0.0031 16.7 1.7 3.4 2 1 3 5 5 5 3 Reovirus sigma C capsid protein Filament PF00038.16 EPS30235.1 - 0.11 11.9 38.3 0.038 13.4 4.5 3.4 3 1 1 4 4 4 0 Intermediate filament protein Fib_alpha PF08702.5 EPS30235.1 - 0.14 12.2 18.6 0.4 10.7 3.6 4.6 4 1 1 5 5 5 0 Fibrinogen alpha/beta chain family Tup_N PF08581.5 EPS30235.1 - 0.22 11.7 23.3 0.076 13.2 1.2 5.1 4 1 0 5 5 5 0 Tup N-terminal Tropomyosin PF00261.15 EPS30235.1 - 0.24 10.4 32.0 0.02 13.9 18.2 2.2 2 0 0 2 2 2 0 Tropomyosin GAS PF13851.1 EPS30235.1 - 0.58 9.3 29.1 0.18 11.0 8.0 4.5 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding ADIP PF11559.3 EPS30235.1 - 3.2 7.6 41.4 0.18 11.7 7.4 4.4 3 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 EPS30235.1 - 3.8 7.0 45.2 0.19 11.2 0.3 5.1 2 1 2 5 5 5 0 IncA protein DUF3506 PF12014.3 EPS30236.1 - 2.3e-49 166.6 0.0 4.1e-49 165.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.2 EPS30236.1 - 2.7e-10 39.8 0.1 5.8e-10 38.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EPS30236.1 - 4.6e-06 26.1 0.1 1.1e-05 24.9 0.1 1.7 1 0 0 1 1 1 1 F-box domain PRANC PF09372.5 EPS30236.1 - 0.056 13.4 0.0 0.092 12.7 0.0 1.3 1 0 0 1 1 1 0 PRANC domain DUF1748 PF08520.5 EPS30237.1 - 1.1e-35 121.1 0.1 1.2e-35 120.9 0.1 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Peptidase_S15 PF02129.13 EPS30237.1 - 0.015 14.7 0.4 0.016 14.6 0.3 1.0 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) PK PF00224.16 EPS30238.1 - 4.7e-173 574.6 2.8 5.8e-173 574.3 1.9 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EPS30238.1 - 4e-32 110.2 0.0 9.6e-32 108.9 0.0 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EPS30238.1 - 0.0002 20.2 0.7 0.00058 18.8 0.3 1.7 1 1 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 EPS30238.1 - 0.0094 14.8 0.1 0.16 10.7 0.0 2.1 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain PIP5K PF01504.13 EPS30239.1 - 2.1e-59 200.7 0.0 4.2e-59 199.6 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 EPS30239.1 - 4.1e-25 88.3 0.0 7.1e-25 87.5 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 EPS30239.1 - 2.7e-14 52.8 5.4 2.7e-14 52.8 3.8 2.0 2 0 0 2 2 2 1 FYVE zinc finger XPC-binding PF09280.6 EPS30239.1 - 0.022 14.2 1.3 0.06 12.8 0.9 1.8 1 0 0 1 1 1 0 XPC-binding domain DZR PF12773.2 EPS30239.1 - 0.63 9.9 8.2 0.24 11.2 2.0 2.8 3 0 0 3 3 3 0 Double zinc ribbon SUR7 PF06687.7 EPS30241.1 - 8.6e-51 172.5 12.1 1e-50 172.2 8.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family VIT1 PF01988.14 EPS30241.1 - 0.028 13.8 4.1 0.023 14.1 0.9 2.3 1 1 1 2 2 2 0 VIT family Tetraspannin PF00335.15 EPS30241.1 - 5.2 6.2 23.4 0.26 10.5 6.6 3.1 2 1 1 3 3 3 0 Tetraspanin family Cellulase PF00150.13 EPS30243.1 - 5.3e-57 193.1 3.0 6.8e-57 192.8 2.0 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Lipase_GDSL PF00657.17 EPS30244.1 - 2.9e-16 60.0 0.6 3.5e-16 59.7 0.4 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF778 PF05608.7 EPS30244.1 - 0.03 14.2 0.0 0.055 13.4 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF778) WD40 PF00400.27 EPS30245.1 - 7.9e-16 57.2 33.9 2.6e-08 33.4 0.5 10.4 12 0 0 12 12 12 6 WD domain, G-beta repeat XPG_N PF00752.12 EPS30246.1 - 1.3e-35 121.6 0.0 3.7e-35 120.2 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EPS30246.1 - 3.1e-24 84.8 0.0 9.6e-24 83.2 0.0 1.9 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 EPS30246.1 - 0.032 14.4 0.0 0.11 12.7 0.0 1.9 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold Cauli_DNA-bind PF03310.8 EPS30246.1 - 0.046 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Caulimovirus DNA-binding protein UIM PF02809.15 EPS30246.1 - 0.093 12.3 2.3 0.19 11.3 0.2 2.9 2 0 0 2 2 2 0 Ubiquitin interaction motif Pil1 PF13805.1 EPS30247.1 - 6.4e-154 510.8 0.6 7.9e-154 510.5 0.4 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 EPS30247.1 - 0.21 10.8 4.1 1.4 8.2 2.9 2.0 1 1 0 1 1 1 0 FAM92 protein Methyltransf_11 PF08241.7 EPS30248.1 - 3.7e-17 62.6 0.0 6.6e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS30248.1 - 5.5e-13 49.4 0.0 1.1e-12 48.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPS30248.1 - 5.4e-12 46.0 0.0 1e-11 45.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPS30248.1 - 2.3e-10 40.2 0.0 3.3e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPS30248.1 - 2.4e-10 40.6 0.0 4.8e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPS30248.1 - 1.2e-09 38.1 0.0 1.6e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPS30248.1 - 1.6e-08 34.6 0.0 3.2e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPS30248.1 - 6.1e-06 25.7 0.0 8.5e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EPS30248.1 - 0.00042 19.5 0.0 0.00062 18.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EPS30248.1 - 0.00044 19.4 0.0 0.00055 19.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FmrO PF07091.6 EPS30248.1 - 0.046 12.7 0.0 0.078 11.9 0.0 1.4 1 1 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) RrnaAD PF00398.15 EPS30248.1 - 0.072 12.1 0.0 0.097 11.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase CheR PF01739.13 EPS30248.1 - 0.12 11.6 0.0 3.8 6.7 0.0 2.3 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain bZIP_2 PF07716.10 EPS30249.1 - 1.7e-12 46.9 14.6 2.9e-12 46.1 10.2 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EPS30249.1 - 0.00013 21.8 14.0 0.00037 20.3 9.7 1.8 1 1 0 1 1 1 1 bZIP transcription factor Herpes_BLRF2 PF05812.7 EPS30249.1 - 0.0011 18.7 2.1 0.0013 18.5 0.2 1.9 1 1 0 1 1 1 1 Herpesvirus BLRF2 protein DUF4094 PF13334.1 EPS30249.1 - 0.0097 16.2 2.5 0.031 14.6 1.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4094) CCDC144C PF14915.1 EPS30249.1 - 0.013 14.4 3.6 0.018 14.0 2.5 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region DUF3552 PF12072.3 EPS30249.1 - 0.018 14.2 6.5 0.029 13.5 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF2462 PF09495.5 EPS30249.1 - 0.2 12.4 3.4 1.2 9.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2462) Fungal_trans PF04082.13 EPS30250.1 - 1.4e-21 76.5 0.1 2.7e-21 75.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Spc7_N PF15402.1 EPS30251.1 - 1.3e-294 979.9 80.2 1.4e-187 625.6 31.6 3.3 2 1 1 3 3 3 3 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.6 EPS30251.1 - 3.8e-119 397.1 6.6 7.7e-119 396.1 4.6 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein IFT57 PF10498.4 EPS30251.1 - 0.0029 16.4 5.9 0.0029 16.4 4.1 2.5 2 0 0 2 2 2 1 Intra-flagellar transport protein 57 Ribosomal_S17 PF00366.15 EPS30252.1 - 7.5e-31 105.9 1.2 1.3e-30 105.2 0.8 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 ANTH PF07651.11 EPS30253.1 - 1e-62 211.3 0.2 1.3e-62 211.0 0.1 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 EPS30253.1 - 9.4e-09 35.1 0.1 7.5e-08 32.2 0.0 2.0 2 0 0 2 2 2 1 ENTH domain Fungal_trans_2 PF11951.3 EPS30256.1 - 3.6e-08 32.4 0.3 4.4e-07 28.8 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Methyltransf_23 PF13489.1 EPS30257.1 - 5e-15 55.5 0.0 7.2e-15 55.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS30257.1 - 9.8e-09 35.7 0.0 3.2e-07 30.9 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPS30257.1 - 1e-05 25.9 0.0 0.00013 22.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EPS30257.1 - 0.00022 20.3 0.0 0.00043 19.3 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_11 PF08241.7 EPS30257.1 - 0.00057 20.3 0.0 0.0013 19.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPS30257.1 - 0.0026 18.0 0.0 0.096 13.0 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPS30257.1 - 0.0033 17.0 0.0 0.042 13.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain CheR PF01739.13 EPS30257.1 - 0.054 12.7 0.0 0.084 12.1 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain MTS PF05175.9 EPS30257.1 - 0.068 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_26 PF13659.1 EPS30257.1 - 0.086 12.8 0.0 0.2 11.7 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Med4 PF10018.4 EPS30257.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 CMAS PF02353.15 EPS30257.1 - 0.15 11.1 0.0 0.51 9.3 0.0 1.9 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Epimerase PF01370.16 EPS30258.1 - 8.3e-20 71.2 0.0 1.5e-19 70.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPS30258.1 - 2.8e-16 59.0 0.0 3.6e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EPS30258.1 - 2.5e-12 47.1 0.0 4.8e-12 46.2 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EPS30258.1 - 6.7e-10 38.3 0.0 1.1e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EPS30258.1 - 1.3e-05 24.5 0.0 2.7e-05 23.5 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 EPS30258.1 - 0.0054 15.6 0.0 0.047 12.5 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EPS30258.1 - 0.037 13.9 0.3 0.13 12.1 0.2 1.9 1 1 0 1 1 1 0 short chain dehydrogenase KR PF08659.5 EPS30258.1 - 0.11 12.1 0.1 0.28 10.8 0.1 1.6 1 1 0 1 1 1 0 KR domain Glyco_hydro_11 PF00457.12 EPS30259.1 - 2.1e-74 248.8 19.8 2.5e-74 248.5 13.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 ING PF12998.2 EPS30260.1 - 0.021 15.1 6.4 0.053 13.7 1.4 2.2 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Grp1_Fun34_YaaH PF01184.14 EPS30261.1 - 1.9e-86 288.7 20.8 2.2e-86 288.4 14.4 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF3671 PF12420.3 EPS30261.1 - 0.33 10.9 2.2 1.6 8.7 1.5 2.0 1 1 1 2 2 2 0 Protein of unknown function MFS_1 PF07690.11 EPS30263.1 - 2.9e-35 121.6 17.5 4.2e-35 121.0 12.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily NfeD PF01957.13 EPS30263.1 - 0.84 9.7 4.8 10 6.2 0.0 3.3 4 0 0 4 4 4 0 NfeD-like C-terminal, partner-binding Oxidored_FMN PF00724.15 EPS30264.1 - 2.4e-96 322.6 0.0 2.8e-96 322.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Tautomerase PF01361.16 EPS30264.1 - 0.022 14.3 0.0 0.08 12.5 0.0 1.9 2 0 0 2 2 2 0 Tautomerase enzyme DUF972 PF06156.8 EPS30265.1 - 3.7 7.9 6.1 1.8 8.9 1.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF972) UpxZ PF06603.6 EPS30266.1 - 0.039 13.9 0.0 0.07 13.1 0.0 1.4 1 0 0 1 1 1 0 UpxZ family of transcription anti-terminator antagonists WD40 PF00400.27 EPS30267.1 - 2.6e-30 103.1 8.9 6.5e-07 28.9 0.0 7.4 8 1 1 9 9 9 5 WD domain, G-beta repeat HIRA_B PF09453.5 EPS30267.1 - 2e-06 27.1 0.2 7.3e-06 25.3 0.1 2.1 1 0 0 1 1 1 1 HIRA B motif eIF2A PF08662.6 EPS30267.1 - 2.1e-05 24.3 0.4 0.024 14.3 0.0 2.9 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EPS30267.1 - 0.026 14.1 2.8 6.3 6.5 0.0 3.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Glyco_transf_20 PF00982.16 EPS30268.1 - 1.3e-146 488.7 0.0 1.8e-146 488.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EPS30268.1 - 7.9e-21 74.0 0.0 1.3e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase MBA1 PF07961.6 EPS30268.1 - 0.011 14.6 0.0 0.018 13.8 0.0 1.2 1 0 0 1 1 1 0 MBA1-like protein Pkinase PF00069.20 EPS30269.1 - 1.5e-06 27.6 0.0 0.0024 17.0 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Rad4 PF03835.10 EPS30270.1 - 7.1e-15 54.6 4.2 1.4e-14 53.7 2.9 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 EPS30270.1 - 1.1e-12 48.1 1.7 2.5e-12 46.9 1.2 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily Glyco_hydro_71 PF03659.9 EPS30272.1 - 9e-142 472.0 7.0 1.1e-141 471.8 4.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF4434 PF14488.1 EPS30272.1 - 0.013 15.2 0.2 0.04 13.6 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4434) DUF1180 PF06679.7 EPS30272.1 - 0.042 13.7 0.2 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) PAP2_3 PF14378.1 EPS30273.1 - 1.1e-15 57.6 24.3 1.8e-14 53.6 4.0 2.7 3 0 0 3 3 3 2 PAP2 superfamily PAP2 PF01569.16 EPS30273.1 - 0.017 14.8 9.4 0.052 13.2 6.5 1.9 1 1 0 1 1 1 0 PAP2 superfamily Memo PF01875.12 EPS30274.1 - 9.9e-63 211.5 0.0 1.3e-62 211.2 0.0 1.1 1 0 0 1 1 1 1 Memo-like protein LSM PF01423.17 EPS30276.1 - 1.2e-06 27.9 0.0 2.6e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EPS30276.1 - 0.00036 20.3 0.0 0.0005 19.9 0.0 1.3 1 1 0 1 1 1 1 Ataxin 2 SM domain Gemin6 PF06372.7 EPS30276.1 - 0.083 12.2 0.0 0.12 11.7 0.0 1.3 1 1 0 1 1 1 0 Gemin6 protein Metallophos PF00149.23 EPS30277.1 - 5.2e-41 140.2 0.3 6.8e-41 139.8 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Condensation PF00668.15 EPS30278.1 - 0.018 13.8 1.7 0.034 12.9 1.2 1.4 1 0 0 1 1 1 0 Condensation domain RabGAP-TBC PF00566.13 EPS30279.1 - 3e-33 115.0 4.2 5.4e-33 114.2 2.9 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Prominin PF05478.6 EPS30279.1 - 0.36 8.3 0.1 0.51 7.8 0.1 1.1 1 0 0 1 1 1 0 Prominin Apolipoprotein PF01442.13 EPS30279.1 - 6 6.3 9.1 12 5.2 3.4 2.4 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Pkinase PF00069.20 EPS30280.1 - 5.8e-58 196.0 0.0 8.7e-58 195.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS30280.1 - 6.8e-20 71.2 0.0 1.1e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPS30280.1 - 5.6e-05 22.2 0.0 9.5e-05 21.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EPS30280.1 - 0.00087 19.0 0.1 0.0069 16.1 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 EPS30280.1 - 0.0012 17.9 0.0 0.0023 17.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EPS30280.1 - 0.0097 15.2 0.2 0.032 13.5 0.1 1.9 2 0 0 2 2 2 1 RIO1 family PAS_9 PF13426.1 EPS30280.1 - 0.035 14.4 0.0 9.9 6.6 0.0 3.7 3 2 0 3 3 3 0 PAS domain F-box-like PF12937.2 EPS30282.1 - 2.3e-11 43.2 0.3 2.3e-11 43.2 0.2 2.6 3 0 0 3 3 3 1 F-box-like LRR_6 PF13516.1 EPS30282.1 - 8e-10 37.7 13.3 0.11 12.5 0.1 6.8 9 0 0 9 9 9 4 Leucine Rich repeat F-box PF00646.28 EPS30282.1 - 9.3e-09 34.7 0.2 3.8e-08 32.7 0.2 2.1 1 0 0 1 1 1 1 F-box domain LRR_1 PF00560.28 EPS30282.1 - 0.00013 21.5 9.1 7.5 7.0 0.0 6.8 6 2 0 6 6 6 1 Leucine Rich Repeat LRR_4 PF12799.2 EPS30282.1 - 0.0048 16.4 6.5 13 5.5 0.0 5.5 5 1 1 6 6 6 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPS30282.1 - 0.012 15.3 6.3 4.2 7.1 0.3 4.5 3 2 2 5 5 5 0 Leucine rich repeat p47_phox_C PF08944.6 EPS30282.1 - 0.013 15.7 0.1 0.051 13.7 0.1 2.0 1 0 0 1 1 1 0 NADPH oxidase subunit p47Phox, C terminal domain LRR_7 PF13504.1 EPS30282.1 - 5.8 7.5 16.4 18 6.0 0.0 6.6 8 0 0 8 8 8 0 Leucine rich repeat Dehyd-heme_bind PF09098.5 EPS30283.1 - 0.0027 17.1 0.8 0.0032 16.9 0.5 1.2 1 0 0 1 1 1 1 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding PVL_ORF50 PF07768.6 EPS30283.1 - 1.5 8.8 9.5 2.1 8.3 6.5 1.3 1 1 0 1 1 1 0 PVL ORF-50-like family AFT PF08731.6 EPS30283.1 - 6.9 6.9 8.6 25 5.0 6.0 1.7 1 1 0 1 1 1 0 Transcription factor AFT DUF1400 PF07176.6 EPS30284.1 - 0.057 13.3 0.2 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1400) DUF2361 PF10153.4 EPS30285.1 - 2.5e-35 121.0 9.7 2.5e-35 121.0 6.8 2.8 3 1 0 3 3 3 1 Uncharacterised conserved protein (DUF2361) zf-rbx1 PF12678.2 EPS30286.1 - 0.0031 17.6 3.3 0.009 16.1 2.3 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EPS30286.1 - 1 9.2 11.5 0.039 13.7 3.1 2.3 2 0 0 2 2 2 0 Ring finger domain PTS_2-RNA PF01885.11 EPS30287.1 - 2.5e-71 238.8 0.1 3.2e-71 238.4 0.1 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family Mucin PF01456.12 EPS30287.1 - 1.8 8.3 14.6 3 7.6 10.1 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Tir_receptor_C PF07489.6 EPS30287.1 - 4.4 6.9 15.3 0.26 11.0 6.8 1.6 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) C-terminus Dioxygenase_C PF00775.16 EPS30288.1 - 2.1e-51 173.7 0.0 2.7e-51 173.4 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EPS30288.1 - 2.9e-13 49.5 0.1 4.6e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EPS30288.1 - 0.00022 21.2 0.0 0.001 19.0 0.0 2.0 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain Abhydrolase_6 PF12697.2 EPS30289.1 - 1.3e-32 113.5 0.1 1.6e-32 113.2 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPS30289.1 - 1.2e-18 67.5 0.0 7.5e-15 55.1 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPS30289.1 - 7.7e-18 64.6 0.1 1.6e-17 63.6 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EPS30289.1 - 4.6e-07 28.6 0.0 6.6e-07 28.0 0.0 1.2 1 0 0 1 1 1 1 Ndr family Esterase PF00756.15 EPS30289.1 - 7.3e-05 22.3 0.3 0.0026 17.2 0.0 2.1 1 1 0 2 2 2 1 Putative esterase Abhydrolase_2 PF02230.11 EPS30289.1 - 0.00011 21.7 0.3 0.18 11.2 0.0 3.0 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase DLH PF01738.13 EPS30289.1 - 0.00012 21.4 0.0 0.36 10.0 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Ser_hydrolase PF06821.8 EPS30289.1 - 0.0024 17.5 0.1 0.013 15.0 0.0 2.1 1 1 1 2 2 2 1 Serine hydrolase Peptidase_S9 PF00326.16 EPS30289.1 - 0.0076 15.4 0.0 0.93 8.6 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family PGAP1 PF07819.8 EPS30289.1 - 0.013 15.1 0.1 0.023 14.3 0.1 1.4 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.9 EPS30289.1 - 0.055 12.7 0.1 0.14 11.4 0.1 1.6 1 1 0 1 1 1 0 Putative serine esterase (DUF676) BAAT_C PF08840.6 EPS30289.1 - 0.06 13.0 0.1 0.4 10.3 0.1 1.9 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Thioesterase PF00975.15 EPS30289.1 - 0.063 13.4 0.0 0.082 13.1 0.0 1.3 1 1 0 1 1 1 0 Thioesterase domain Aldo_ket_red PF00248.16 EPS30291.1 - 2.5e-47 161.0 0.0 3.3e-47 160.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family eRF1_1 PF03463.10 EPS30292.1 - 1.4e-45 154.1 0.0 2.2e-45 153.4 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.10 EPS30292.1 - 1.4e-19 70.3 0.0 3e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.10 EPS30292.1 - 2e-19 70.2 0.0 3.1e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 Myb_DNA-bind_3 PF12776.2 EPS30293.1 - 0.18 12.4 4.7 8.4 7.0 0.1 2.3 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain ER_lumen_recept PF00810.13 EPS30294.1 - 2.1e-38 132.0 7.1 4.1e-38 131.1 4.9 1.5 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EPS30294.1 - 0.018 14.5 0.0 0.018 14.5 0.0 4.1 5 1 0 5 5 5 0 PQ loop repeat AGTRAP PF06396.6 EPS30294.1 - 0.37 10.4 7.5 0.03 14.0 1.8 1.7 2 0 0 2 2 2 0 Angiotensin II, type I receptor-associated protein (AGTRAP) Myb_DNA-binding PF00249.26 EPS30295.1 - 1.3e-12 47.5 5.2 2.8e-07 30.4 2.1 3.0 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EPS30295.1 - 2e-09 37.3 1.6 1e-06 28.7 0.4 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Transp_cyt_pur PF02133.10 EPS30296.1 - 6.1e-18 64.5 39.4 9.3e-18 63.9 27.3 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin COX5B PF01215.14 EPS30297.1 - 3.7e-36 123.8 0.0 1.8e-34 118.2 0.0 2.0 1 1 1 2 2 2 2 Cytochrome c oxidase subunit Vb LysM PF01476.15 EPS30298.1 - 0.00048 19.9 0.0 0.0013 18.5 0.0 1.8 2 0 0 2 2 2 1 LysM domain Chitin_bind_1 PF00187.14 EPS30298.1 - 0.48 10.4 8.1 2.1 8.4 5.6 2.2 1 0 0 1 1 1 0 Chitin recognition protein DUF2235 PF09994.4 EPS30299.1 - 9.9e-71 238.3 0.0 1.7e-70 237.5 0.0 1.4 2 0 0 2 2 2 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 EPS30299.1 - 0.11 12.3 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase family Myb_DNA-bind_6 PF13921.1 EPS30300.1 - 1.3e-12 47.6 0.3 1.6e-07 31.2 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EPS30300.1 - 8.9e-11 41.6 0.1 9e-06 25.6 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain DNA_ligase_A_C PF04679.10 EPS30300.1 - 0.074 13.4 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 ATP dependent DNA ligase C terminal region PROCN PF08083.6 EPS30301.1 - 2.8e-223 740.7 7.9 3.6e-223 740.4 4.9 1.6 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 EPS30301.1 - 1.8e-125 416.8 1.6 3.1e-125 416.0 1.1 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 EPS30301.1 - 9.9e-101 333.7 0.2 5.2e-62 207.9 0.1 2.6 2 0 0 2 2 2 2 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 EPS30301.1 - 1.1e-77 258.8 2.1 3.2e-77 257.3 1.5 1.9 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 EPS30301.1 - 5.5e-67 223.5 0.2 1.1e-66 222.5 0.1 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 Hom_end_hint PF05203.11 EPS30301.1 - 3.6e-52 177.2 7.1 1.1e-31 110.2 0.0 3.3 2 1 1 3 3 3 2 Hom_end-associated Hint PROCT PF08084.6 EPS30301.1 - 1.6e-46 157.0 0.0 4.6e-46 155.5 0.0 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.4 EPS30301.1 - 9.7e-45 150.3 0.3 2.8e-44 148.9 0.2 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 Hint_2 PF13403.1 EPS30301.1 - 0.00034 20.5 0.0 0.002 18.0 0.0 2.1 1 1 0 1 1 1 1 Hint domain DUF3753 PF12575.3 EPS30301.1 - 0.097 12.4 0.0 0.27 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) OCD_Mu_crystall PF02423.10 EPS30301.1 - 0.15 10.8 1.0 0.25 10.0 0.7 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Ribosomal_L34e PF01199.13 EPS30302.1 - 5.8e-37 125.8 2.9 7.5e-37 125.4 2.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e DUF1428 PF07237.6 EPS30302.1 - 0.097 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) Fork_head PF00250.13 EPS30303.1 - 2.1e-13 50.1 0.0 3.5e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Fork head domain Cactin_mid PF10312.4 EPS30305.1 - 1.3e-64 216.9 5.5 2.2e-64 216.2 3.8 1.4 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 EPS30305.1 - 5.1e-56 187.6 4.6 8.6e-56 186.9 3.2 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein XLF PF09302.6 EPS30306.1 - 5.5e-31 107.6 0.1 1.1e-30 106.6 0.0 1.5 1 0 0 1 1 1 1 XLF (XRCC4-like factor) YL1 PF05764.8 EPS30306.1 - 7.3 6.1 18.4 0.19 11.2 5.4 2.5 2 1 0 2 2 2 0 YL1 nuclear protein WD40 PF00400.27 EPS30307.1 - 5.4e-31 105.3 6.8 5.1e-10 38.8 0.0 7.2 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EPS30307.1 - 2.8e-05 23.8 0.0 0.21 11.2 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PHD PF00628.24 EPS30307.1 - 4.2 7.1 10.2 0.18 11.5 0.7 2.4 2 0 0 2 2 2 0 PHD-finger ABC_tran PF00005.22 EPS30309.1 - 9.9e-33 113.3 0.0 4.7e-32 111.1 0.0 2.1 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 EPS30309.1 - 6.2e-26 91.4 7.1 6.2e-26 91.4 4.9 2.0 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.14 EPS30309.1 - 4.2e-07 29.4 1.5 1.2e-05 24.6 0.2 2.8 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EPS30309.1 - 0.00013 22.0 0.0 0.11 12.4 0.0 2.3 1 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EPS30309.1 - 0.00057 19.9 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain SbcCD_C PF13558.1 EPS30309.1 - 0.0053 16.6 0.3 0.064 13.1 0.2 2.6 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 EPS30309.1 - 0.0072 15.8 0.2 0.022 14.3 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EPS30309.1 - 0.012 15.7 0.6 0.15 12.2 0.4 2.3 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EPS30309.1 - 0.041 13.0 0.0 0.086 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF498 PF04430.9 EPS30310.1 - 1.1e-25 89.3 0.0 2.7e-25 88.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF498/DUF598) E_Pc_C PF06752.7 EPS30310.1 - 0.0031 17.0 0.6 0.0046 16.4 0.4 1.2 1 0 0 1 1 1 1 Enhancer of Polycomb C-terminus DUF1131 PF06572.7 EPS30310.1 - 0.08 12.4 0.0 0.34 10.3 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1131) Alk_phosphatase PF00245.15 EPS30311.1 - 1.2e-113 379.9 0.1 1.5e-113 379.6 0.1 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 EPS30311.1 - 0.0006 19.2 0.0 0.0011 18.3 0.0 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily RskA PF10099.4 EPS30311.1 - 0.014 15.1 0.0 0.032 13.9 0.0 1.6 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Glyco_hydro_16 PF00722.16 EPS30312.1 - 3.8e-42 143.6 8.5 6.7e-42 142.8 5.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Baculo_VP91_N PF08475.5 EPS30312.1 - 0.049 12.9 0.0 0.09 12.1 0.0 1.3 1 0 0 1 1 1 0 Viral capsid protein 91 N-terminal Chitin_bind_1 PF00187.14 EPS30312.1 - 0.37 10.8 15.6 0.81 9.7 10.8 1.5 1 0 0 1 1 1 0 Chitin recognition protein Period_C PF12114.3 EPS30312.1 - 3.7 7.0 11.7 7.4 6.1 8.1 1.5 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Fungal_trans_2 PF11951.3 EPS30313.1 - 0.0009 17.9 0.1 0.0012 17.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MIT PF04212.13 EPS30313.1 - 0.086 12.7 0.2 17 5.3 0.0 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain PMSR PF01625.16 EPS30314.1 - 2.2e-59 199.8 0.2 2.8e-59 199.4 0.2 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Kinesin PF00225.18 EPS30315.1 - 1.2e-114 382.5 0.0 1.9e-114 381.8 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain AAA_33 PF13671.1 EPS30315.1 - 0.015 15.1 0.0 0.17 11.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain DYW_deaminase PF14432.1 EPS30315.1 - 0.078 12.9 0.8 0.22 11.5 0.1 2.1 2 0 0 2 2 2 0 DYW family of nucleic acid deaminases Tim17 PF02466.14 EPS30317.1 - 7.5e-05 22.7 1.9 0.00012 22.1 1.3 1.4 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family cNMP_binding PF00027.24 EPS30318.1 - 5e-36 122.3 0.0 5.8e-20 70.8 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.1 EPS30318.1 - 9.7e-15 52.9 2.1 0.69 10.1 0.1 9.1 10 0 0 10 10 10 3 Leucine Rich repeat LRR_1 PF00560.28 EPS30318.1 - 5.2e-07 28.8 1.5 7 7.0 0.2 8.0 8 1 1 9 9 9 1 Leucine Rich Repeat LRR_8 PF13855.1 EPS30318.1 - 4e-06 26.4 0.0 0.046 13.4 0.2 3.8 3 0 0 3 3 3 1 Leucine rich repeat F-box-like PF12937.2 EPS30318.1 - 8.3e-06 25.4 0.1 2.9e-05 23.7 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EPS30318.1 - 1.3e-05 24.6 0.0 4.8e-05 22.8 0.0 2.0 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.2 EPS30318.1 - 0.0008 18.9 1.7 1.3 8.7 0.0 4.4 3 1 3 6 6 6 1 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EPS30318.1 - 0.0013 18.6 6.1 42 4.9 0.0 6.7 7 0 0 7 7 7 0 Leucine rich repeat Cupin_3 PF05899.7 EPS30318.1 - 0.013 14.8 0.1 0.9 8.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Ste50p-SAM PF09235.5 EPS30318.1 - 0.061 13.3 0.4 5.4 7.1 0.1 3.1 2 1 0 2 2 2 0 Ste50p, sterile alpha motif PapG_N PF03627.8 EPS30319.1 - 0.13 11.6 0.0 0.13 11.6 0.0 1.0 1 0 0 1 1 1 0 PapG carbohydrate binding domain Slx4 PF09494.5 EPS30320.1 - 1.1e-27 95.4 0.1 2.3e-27 94.4 0.1 1.6 1 0 0 1 1 1 1 Slx4 endonuclease DUF3399 PF11879.3 EPS30321.1 - 4.8 7.4 7.5 22 5.3 0.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3399) Zn_clus PF00172.13 EPS30323.1 - 1.7e-05 24.6 10.9 3.2e-05 23.7 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TMF_DNA_bd PF12329.3 EPS30323.1 - 0.00024 20.8 5.8 0.088 12.6 1.1 2.5 2 0 0 2 2 2 2 TATA element modulatory factor 1 DNA binding HALZ PF02183.13 EPS30323.1 - 0.033 13.9 5.7 0.34 10.6 0.2 2.6 3 0 0 3 3 2 0 Homeobox associated leucine zipper DivIC PF04977.10 EPS30323.1 - 0.077 12.4 9.4 1.8 8.1 0.4 2.4 2 0 0 2 2 2 0 Septum formation initiator DUF3450 PF11932.3 EPS30323.1 - 0.083 12.1 4.5 0.52 9.5 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) MAD PF05557.8 EPS30323.1 - 0.13 10.3 9.1 0.46 8.5 6.3 1.8 1 1 0 1 1 1 0 Mitotic checkpoint protein DUF3373 PF11853.3 EPS30323.1 - 0.14 10.6 6.9 0.09 11.2 1.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3373) DUF904 PF06005.7 EPS30323.1 - 0.14 12.4 7.0 1.6 9.1 1.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF4140 PF13600.1 EPS30323.1 - 0.15 12.5 6.4 4.9 7.6 0.2 3.1 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF2681 PF10883.3 EPS30323.1 - 0.17 12.1 8.3 1.6 8.9 0.0 2.7 3 0 0 3 3 2 0 Protein of unknown function (DUF2681) Herpes_BLRF2 PF05812.7 EPS30323.1 - 0.23 11.2 4.8 10 5.9 0.6 3.0 3 0 0 3 3 3 0 Herpesvirus BLRF2 protein PEP-utilisers_N PF05524.8 EPS30323.1 - 0.24 11.2 7.2 2.9 7.7 5.0 2.1 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal Cluap1 PF10234.4 EPS30323.1 - 0.57 9.3 5.6 2.7 7.0 1.2 2.1 1 1 1 2 2 2 0 Clusterin-associated protein-1 IncA PF04156.9 EPS30323.1 - 1.2 8.6 11.4 22 4.5 0.4 2.3 1 1 1 2 2 2 0 IncA protein DivIVA PF05103.8 EPS30323.1 - 3.4 7.7 7.5 19 5.2 0.9 2.4 1 1 1 2 2 2 0 DivIVA protein ADIP PF11559.3 EPS30323.1 - 3.9 7.3 12.0 4.7 7.0 0.0 2.6 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 EPS30323.1 - 10 6.5 9.0 17 5.7 1.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF972) CGI-121 PF08617.5 EPS30324.1 - 1.9e-50 170.6 0.0 2.2e-50 170.4 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Bax1-I PF01027.15 EPS30325.1 - 8.1e-31 107.2 11.6 1.3e-30 106.5 8.0 1.3 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF2537 PF10801.3 EPS30325.1 - 0.2 11.7 7.4 1.7 8.8 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2537) RRM_1 PF00076.17 EPS30326.1 - 1.1e-16 60.1 0.0 1.7e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS30326.1 - 2e-13 50.1 0.0 3e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS30326.1 - 6.7e-12 45.0 0.0 9.7e-12 44.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EPS30326.1 - 0.059 13.2 0.0 0.095 12.5 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif IATP PF04568.7 EPS30327.1 - 9e-26 89.8 0.2 1e-25 89.6 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Atg14 PF10186.4 EPS30327.1 - 0.0046 15.9 0.1 0.0046 15.9 0.1 1.0 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DUF4078 PF13300.1 EPS30327.1 - 0.063 13.3 0.7 0.082 13.0 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4078) BLOC1_2 PF10046.4 EPS30327.1 - 0.088 12.9 0.7 0.12 12.5 0.5 1.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IncA PF04156.9 EPS30327.1 - 0.089 12.3 1.3 0.11 12.1 0.9 1.1 1 0 0 1 1 1 0 IncA protein DASH_Dad2 PF08654.5 EPS30327.1 - 0.11 12.5 0.9 0.17 11.8 0.6 1.4 1 0 0 1 1 1 0 DASH complex subunit Dad2 RBD-FIP PF09457.5 EPS30327.1 - 0.2 11.4 1.3 0.31 10.8 0.9 1.3 1 0 0 1 1 1 0 FIP domain DivIC PF04977.10 EPS30327.1 - 0.21 11.1 1.2 0.3 10.6 0.8 1.3 1 0 0 1 1 1 0 Septum formation initiator 14-3-3 PF00244.15 EPS30329.1 - 8.8e-115 381.7 7.0 1e-114 381.5 4.8 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF2205 PF10224.4 EPS30331.1 - 5.4e-31 106.0 3.3 5.4e-31 106.0 2.3 1.6 2 0 0 2 2 2 1 Predicted coiled-coil protein (DUF2205) Macoilin PF09726.4 EPS30331.1 - 0.0034 15.7 3.2 0.0039 15.5 2.2 1.0 1 0 0 1 1 1 1 Transmembrane protein Dynamitin PF04912.9 EPS30331.1 - 0.01 14.7 0.7 0.014 14.2 0.5 1.1 1 0 0 1 1 1 0 Dynamitin IncA PF04156.9 EPS30331.1 - 0.016 14.8 1.1 0.016 14.7 0.8 1.2 1 0 0 1 1 1 0 IncA protein DUF972 PF06156.8 EPS30331.1 - 0.016 15.5 2.7 0.026 14.8 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Spectrin PF00435.16 EPS30331.1 - 0.029 14.6 1.2 0.049 13.9 0.8 1.4 1 0 0 1 1 1 0 Spectrin repeat DASH_Dam1 PF08653.5 EPS30331.1 - 0.05 13.3 0.1 0.092 12.5 0.0 1.5 1 0 0 1 1 1 0 DASH complex subunit Dam1 DivIC PF04977.10 EPS30331.1 - 0.056 12.9 2.0 0.093 12.2 1.4 1.4 1 0 0 1 1 1 0 Septum formation initiator HALZ PF02183.13 EPS30331.1 - 0.089 12.5 4.3 0.56 9.9 0.1 2.3 1 1 1 2 2 2 0 Homeobox associated leucine zipper Sas10_Utp3 PF04000.10 EPS30331.1 - 0.097 12.8 0.4 0.21 11.8 0.3 1.5 1 0 0 1 1 1 0 Sas10/Utp3/C1D family Glutaredoxin2_C PF04399.8 EPS30331.1 - 0.11 12.0 0.1 0.16 11.5 0.1 1.2 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain OmpH PF03938.9 EPS30331.1 - 0.11 12.3 5.2 0.15 11.9 3.6 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ADIP PF11559.3 EPS30331.1 - 0.12 12.2 4.9 0.15 11.9 3.4 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4140 PF13600.1 EPS30331.1 - 0.13 12.7 3.7 0.055 13.9 1.0 1.7 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Glyco_hydro_76 PF03663.9 EPS30335.1 - 1.9e-22 80.1 1.1 2.5e-14 53.4 0.0 3.2 2 1 0 2 2 2 2 Glycosyl hydrolase family 76 Nsp1_C PF05064.8 EPS30336.1 - 1e-42 144.4 3.0 2.5e-42 143.2 2.1 1.6 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 EPS30336.1 - 2.1e-08 34.3 100.6 3.1e-06 27.3 33.1 4.8 1 1 3 4 4 4 3 Nucleoporin FG repeat region Peptidase_S64 PF08192.6 EPS30336.1 - 0.47 8.7 6.0 0.33 9.2 3.3 1.3 1 1 0 1 1 1 0 Peptidase family S64 ParB PF08775.5 EPS30336.1 - 0.53 10.5 3.7 0.18 12.0 0.2 1.9 2 1 0 2 2 2 0 ParB family AAA_13 PF13166.1 EPS30336.1 - 0.66 8.3 8.2 1.3 7.3 4.6 1.8 1 1 0 1 1 1 0 AAA domain DUF1664 PF07889.7 EPS30336.1 - 0.76 9.5 4.6 0.72 9.6 0.3 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Laminin_II PF06009.7 EPS30336.1 - 0.78 9.4 11.1 6.5 6.5 2.4 2.7 1 1 1 2 2 2 0 Laminin Domain II DUF4407 PF14362.1 EPS30336.1 - 1.4 7.8 6.9 2.3 7.0 4.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4200 PF13863.1 EPS30336.1 - 1.7 8.6 10.3 0.13 12.1 2.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF4593 PF15263.1 EPS30337.1 - 0.0068 16.3 1.6 0.033 14.0 1.1 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4593) zf-MIZ PF02891.15 EPS30338.1 - 1.2e-11 43.9 0.2 2.9e-11 42.6 0.1 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 EPS30338.1 - 0.026 14.0 0.2 0.083 12.4 0.1 2.0 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Rubredoxin PF00301.15 EPS30338.1 - 0.05 13.4 0.3 0.12 12.2 0.2 1.6 1 0 0 1 1 1 0 Rubredoxin SH3_9 PF14604.1 EPS30339.1 - 4.6e-14 51.7 0.0 8.8e-14 50.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 EPS30339.1 - 3.7e-12 46.3 0.0 1.2e-11 44.7 0.0 1.9 1 0 0 1 1 1 1 PH domain SH3_1 PF00018.23 EPS30339.1 - 1e-09 37.6 0.1 2.1e-09 36.6 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SAM_2 PF07647.12 EPS30339.1 - 5.9e-08 32.4 0.1 9.9e-08 31.7 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.1 EPS30339.1 - 3.1e-06 27.4 0.2 1.1e-05 25.5 0.2 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain SH3_2 PF07653.12 EPS30339.1 - 8.5e-06 25.1 0.1 1.8e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.25 EPS30339.1 - 0.0063 16.6 0.2 0.011 15.8 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Metallophos PF00149.23 EPS30340.1 - 0.00031 20.2 8.7 0.0012 18.2 6.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_L14 PF00238.14 EPS30341.1 - 3.2e-33 114.0 0.0 3.6e-33 113.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Hist_deacetyl PF00850.14 EPS30342.1 - 3e-79 266.5 0.0 4.9e-79 265.8 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain JAB PF01398.16 EPS30343.1 - 6.1e-36 122.6 0.1 1.4e-35 121.4 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EPS30343.1 - 1.3e-27 96.1 3.0 2.3e-27 95.3 2.1 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EPS30343.1 - 5.5e-09 35.5 0.0 1.1e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UCR_14kD PF02271.11 EPS30343.1 - 0.079 12.7 0.4 0.22 11.3 0.1 1.9 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase complex 14kD subunit F-box-like_2 PF13013.1 EPS30344.1 - 0.02 14.5 0.1 0.041 13.5 0.0 1.6 1 1 0 1 1 1 0 F-box-like domain NIF PF03031.13 EPS30345.1 - 1e-39 135.7 0.1 1.5e-39 135.2 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 EPS30345.1 - 0.09 12.9 0.3 0.25 11.5 0.0 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Mucin PF01456.12 EPS30345.1 - 6 6.6 7.7 10 5.9 5.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Fungal_trans PF04082.13 EPS30346.1 - 2.7e-19 69.0 0.0 6.4e-19 67.8 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS30346.1 - 8e-07 28.8 6.8 1.8e-06 27.7 4.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.2 EPS30347.1 - 0.0011 18.5 0.4 0.0024 17.5 0.2 1.5 1 0 0 1 1 1 1 F-box-like DUF1399 PF07173.7 EPS30348.1 - 1.9e-20 73.5 2.6 2.3e-18 66.7 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1399) EF-1_beta_acid PF10587.4 EPS30348.1 - 0.2 11.8 0.5 0.55 10.4 0.4 1.7 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region Fungal_trans PF04082.13 EPS30349.1 - 8.8e-13 47.7 0.9 8.8e-13 47.7 0.6 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS30349.1 - 3.1e-06 26.9 10.7 3.1e-06 26.9 7.4 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 EPS30353.1 - 1e-68 231.2 0.0 1.5e-68 230.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS30353.1 - 1.7e-32 112.4 0.0 7.9e-31 107.0 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPS30353.1 - 0.012 14.6 0.2 2 7.3 0.0 2.4 2 0 0 2 2 2 0 Kinase-like Peptidase_S10 PF00450.17 EPS30354.1 - 9.4e-89 298.4 0.6 1.2e-88 298.0 0.4 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Noggin PF05806.7 EPS30356.1 - 0.06 12.6 0.0 0.07 12.4 0.0 1.0 1 0 0 1 1 1 0 Noggin MFS_1 PF07690.11 EPS30357.1 - 7.9e-30 103.7 46.5 7.9e-30 103.7 32.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS30357.1 - 1.8e-07 30.1 13.5 1.8e-07 30.1 9.3 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter MFS_1 PF07690.11 EPS30358.1 - 2.9e-30 105.2 37.6 2.3e-19 69.3 17.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS30358.1 - 5.2e-22 78.0 20.5 1e-21 77.1 14.2 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter Nucleoside_tran PF01733.13 EPS30358.1 - 0.062 12.4 5.0 2.7 7.0 0.1 2.5 2 0 0 2 2 2 0 Nucleoside transporter CN_hydrolase PF00795.17 EPS30359.1 - 1e-34 119.5 0.0 1.4e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase FGase PF05013.7 EPS30359.1 - 0.075 12.9 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 N-formylglutamate amidohydrolase HAMP PF00672.20 EPS30362.1 - 1.8e-49 165.7 17.2 8.1e-10 38.7 0.4 6.9 6 0 0 6 6 6 6 HAMP domain HATPase_c PF02518.21 EPS30362.1 - 2e-31 107.9 0.2 7.2e-31 106.1 0.1 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EPS30362.1 - 2.3e-27 95.2 0.5 1.1e-25 89.8 0.2 3.0 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EPS30362.1 - 4.5e-16 58.5 0.1 4.5e-16 58.5 0.1 4.6 6 0 0 6 6 5 1 His Kinase A (phospho-acceptor) domain DUF2365 PF10157.4 EPS30362.1 - 0.0021 17.9 16.1 1.6 8.5 0.0 6.9 6 2 0 7 7 7 2 Uncharacterized conserved protein (DUF2365) NOD PF06816.8 EPS30362.1 - 0.04 12.9 0.1 1.2 8.3 0.0 2.7 2 0 0 2 2 2 0 NOTCH protein AAA_13 PF13166.1 EPS30362.1 - 0.081 11.3 28.7 0.14 10.5 2.2 4.1 1 1 2 4 4 4 0 AAA domain PilJ PF13675.1 EPS30362.1 - 0.24 11.7 9.4 10 6.4 0.1 5.8 4 2 2 6 6 5 0 Type IV pili methyl-accepting chemotaxis transducer N-term Pox_A_type_inc PF04508.7 EPS30362.1 - 0.46 10.4 2.9 1.1 9.1 0.1 3.2 3 0 0 3 3 2 0 Viral A-type inclusion protein repeat IncA PF04156.9 EPS30362.1 - 1.4 8.4 14.9 3.2 7.3 4.3 4.0 4 0 0 4 4 4 0 IncA protein Scaffolding_pro PF11418.3 EPS30362.1 - 1.4 9.2 13.4 39 4.6 0.0 5.9 5 1 0 5 5 5 0 Phi29 scaffolding protein NAAA-beta PF15508.1 EPS30362.1 - 1.8 8.9 6.2 19 5.7 0.1 5.1 6 1 0 6 6 4 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase tRNA-synt_2d PF01409.15 EPS30363.1 - 1.2e-88 296.4 0.0 1.6e-88 296.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 EPS30363.1 - 0.0001 21.1 0.2 0.0017 17.1 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 EPS30363.1 - 0.00034 20.2 0.0 0.00076 19.1 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_His PF13393.1 EPS30363.1 - 0.082 11.9 0.2 0.31 10.0 0.0 1.8 2 0 0 2 2 2 0 Histidyl-tRNA synthetase Ribosomal_S21e PF01249.13 EPS30364.1 - 8.3e-42 141.0 0.1 9.2e-42 140.8 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e NUDIX PF00293.23 EPS30365.1 - 5.1e-14 52.0 0.0 4.6e-12 45.7 0.0 2.6 1 1 0 1 1 1 1 NUDIX domain IMPDH PF00478.20 EPS30366.1 - 1.5e-130 435.1 2.0 1.9e-130 434.8 1.4 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 EPS30366.1 - 2.2e-18 65.7 0.0 1.4e-08 34.3 0.0 2.4 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 EPS30366.1 - 4.7e-08 32.5 2.7 0.00012 21.3 1.8 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 EPS30366.1 - 5.1e-07 28.8 1.2 1.4e-06 27.4 0.4 1.9 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 EPS30366.1 - 0.00074 18.8 1.4 0.002 17.4 1.0 1.6 1 1 0 1 1 1 1 Histidine biosynthesis protein Aldolase PF01081.14 EPS30366.1 - 0.0083 15.3 0.6 0.074 12.2 0.1 2.3 1 1 1 2 2 2 1 KDPG and KHG aldolase DUF952 PF06108.7 EPS30367.1 - 4e-25 87.4 0.0 4.8e-25 87.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) RasGAP_C PF03836.10 EPS30368.1 - 7.5e-47 158.5 3.9 3e-46 156.6 2.7 2.2 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.14 EPS30368.1 - 4.5e-35 121.1 0.0 1.6e-34 119.2 0.0 2.0 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CH PF00307.26 EPS30368.1 - 3.7e-11 43.0 0.0 1.2e-10 41.4 0.0 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain IQ PF00612.22 EPS30368.1 - 7.9e-10 37.4 54.1 0.66 9.7 0.0 14.3 15 0 0 15 15 15 6 IQ calmodulin-binding motif ENTH PF01417.15 EPS30369.1 - 6.6e-45 152.0 0.1 9.1e-45 151.5 0.1 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EPS30369.1 - 0.00012 20.8 0.0 0.00019 20.2 0.0 1.2 1 0 0 1 1 1 1 ANTH domain Chorismate_synt PF01264.16 EPS30369.1 - 0.095 11.1 0.2 0.16 10.4 0.1 1.2 1 0 0 1 1 1 0 Chorismate synthase SH3_9 PF14604.1 EPS30370.1 - 1.1e-11 44.1 0.1 2.2e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EPS30370.1 - 8.4e-11 41.0 0.0 1.4e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EPS30370.1 - 6.8e-09 35.0 0.0 1.2e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain HMG-CoA_red PF00368.13 EPS30373.1 - 1.9e-154 513.8 4.0 2.6e-154 513.4 2.7 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 EPS30373.1 - 7.5e-53 178.3 0.2 1.4e-52 177.4 0.2 1.5 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 EPS30373.1 - 2.4e-12 46.5 3.6 1e-11 44.5 2.5 2.0 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 EPS30373.1 - 3.1e-05 22.1 2.0 4.6e-05 21.5 1.4 1.1 1 0 0 1 1 1 1 Patched family DUF2304 PF10066.4 EPS30373.1 - 0.042 13.7 0.1 0.093 12.5 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) GIT_SHD PF08518.6 EPS30374.1 - 2e-24 84.6 5.6 1.4e-14 53.1 0.6 2.6 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT DUF327 PF03885.8 EPS30374.1 - 0.014 15.1 0.0 0.014 15.1 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF327) DUF1843 PF08898.5 EPS30374.1 - 0.16 12.0 0.0 0.16 12.0 0.0 3.8 5 0 0 5 5 5 0 Domain of unknown function (DUF1843) AAA_32 PF13654.1 EPS30374.1 - 0.4 9.2 18.6 0.11 11.1 9.9 2.1 2 0 0 2 2 2 0 AAA domain GP41 PF00517.12 EPS30374.1 - 1.5 8.3 6.3 0.21 11.1 0.9 2.1 2 0 0 2 2 2 0 Retroviral envelope protein APG6 PF04111.7 EPS30374.1 - 8.5 5.3 29.0 0.087 11.8 12.6 2.3 1 1 1 2 2 2 0 Autophagy protein Apg6 Glyco_transf_8 PF01501.15 EPS30375.1 - 4.7e-24 85.0 0.0 6.1e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 8 Pro_isomerase PF00160.16 EPS30376.1 - 3.2e-43 147.5 0.1 3.8e-43 147.3 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ctr PF04145.10 EPS30377.1 - 7.2e-44 149.3 0.0 1.1e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 Ctr copper transporter family RNase_PH PF01138.16 EPS30378.1 - 1.9e-33 115.6 0.5 1.2e-32 113.0 0.2 1.9 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Coiled PF05710.7 EPS30378.1 - 0.015 15.7 2.4 0.039 14.4 1.7 1.7 1 0 0 1 1 1 0 Coiled coil SNF2_N PF00176.18 EPS30379.1 - 4.1e-55 186.6 0.1 6.3e-55 186.0 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.1 EPS30379.1 - 3.6e-24 84.4 0.0 1.2e-23 82.7 0.0 2.0 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.26 EPS30379.1 - 1e-14 54.1 0.0 3.8e-13 49.0 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPS30379.1 - 0.00034 20.5 3.4 0.0013 18.6 0.0 3.4 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit Ssu72 PF04722.8 EPS30380.1 - 1.3e-84 282.4 0.0 1.5e-84 282.1 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Mito_fiss_reg PF05308.6 EPS30380.1 - 6.1 6.1 8.4 9.6 5.4 5.8 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Isochorismatase PF00857.15 EPS30381.1 - 8e-21 74.7 0.1 1.5e-20 73.8 0.0 1.4 1 1 0 1 1 1 1 Isochorismatase family DUF3605 PF12239.3 EPS30382.1 - 3e-62 209.1 1.8 3e-62 209.1 1.3 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3605) Oxysterol_BP PF01237.13 EPS30383.1 - 5.1e-91 304.7 0.0 6.7e-91 304.4 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Hist_deacetyl PF00850.14 EPS30384.1 - 2.4e-77 260.2 0.5 3.3e-77 259.8 0.4 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Zn_clus PF00172.13 EPS30385.1 - 2.9e-09 36.6 11.5 6.4e-09 35.5 8.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PEP_mutase PF13714.1 EPS30386.1 - 1.8e-51 174.6 0.6 2.1e-51 174.4 0.4 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 EPS30386.1 - 7.1e-20 70.7 0.2 9.8e-20 70.2 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.10 EPS30386.1 - 0.034 13.2 0.3 0.22 10.6 0.2 2.0 1 1 0 1 1 1 0 Ketopantoate hydroxymethyltransferase MGC-24 PF05283.6 EPS30388.1 - 1.4 8.7 11.9 2.4 7.9 8.3 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) DUF3433 PF11915.3 EPS30389.1 - 1.5e-31 108.3 9.9 2.8e-19 69.0 1.5 3.5 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) PRD_Mga PF08270.6 EPS30389.1 - 0.19 10.9 0.1 0.34 10.1 0.1 1.3 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) PRD domain Tom37_C PF11801.3 EPS30390.1 - 1.1e-38 132.7 0.0 1.7e-38 132.1 0.0 1.2 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 EPS30390.1 - 2.2e-26 91.8 0.3 3.6e-25 88.0 0.0 2.6 3 0 0 3 3 3 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.1 EPS30390.1 - 0.0034 17.2 0.1 0.012 15.5 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Lipase_GDSL PF00657.17 EPS30391.1 - 7.6e-19 68.4 0.1 9.5e-19 68.1 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EPS30391.1 - 4.7e-05 23.5 4.6 0.00016 21.8 3.2 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Zip PF02535.17 EPS30396.1 - 1.1e-56 192.2 15.0 1.2e-56 192.0 10.4 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DUF872 PF05915.7 EPS30396.1 - 0.037 13.8 0.1 1.4 8.7 0.1 2.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Sugar_tr PF00083.19 EPS30397.1 - 3.5e-48 164.3 31.0 2.4e-47 161.5 21.5 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS30397.1 - 1.9e-15 56.4 38.3 1.6e-07 30.4 10.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF606 PF04657.8 EPS30397.1 - 0.026 14.6 19.3 0.042 13.9 1.8 3.6 3 0 0 3 3 3 0 Protein of unknown function, DUF606 MFS_2 PF13347.1 EPS30397.1 - 0.052 11.9 27.6 0.018 13.4 0.6 3.1 1 1 2 3 3 3 0 MFS/sugar transport protein FKBP_C PF00254.23 EPS30398.1 - 1.6e-33 114.5 0.0 1.9e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Cyt-b5 PF00173.23 EPS30399.1 - 1.1e-13 50.7 0.0 1.7e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PP2C PF00481.16 EPS30400.1 - 5.7e-42 143.8 0.0 6.5e-42 143.6 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EPS30400.1 - 5.7e-08 32.4 0.0 2.5e-07 30.3 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EPS30400.1 - 0.00033 20.4 0.0 0.15 11.7 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) FmdA_AmdA PF03069.10 EPS30402.1 - 2.6e-52 177.7 0.0 2.8e-27 95.3 0.0 2.4 1 1 1 2 2 2 2 Acetamidase/Formamidase family UvrD_C PF13361.1 EPS30403.1 - 4.3e-69 233.6 0.0 6.5e-69 233.0 0.0 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 EPS30403.1 - 3.9e-63 213.6 0.1 9.9e-62 209.0 0.1 2.2 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 EPS30403.1 - 1.6e-13 50.6 0.0 4.3e-13 49.2 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EPS30403.1 - 2.5e-12 46.3 0.0 3.6e-11 42.6 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_12 PF13087.1 EPS30403.1 - 2.1e-05 23.9 0.0 0.0013 18.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EPS30403.1 - 2.2e-05 24.0 0.4 0.078 12.4 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EPS30403.1 - 2.4e-05 24.0 0.0 0.00084 18.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EPS30403.1 - 0.0002 21.0 0.2 0.0011 18.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EPS30403.1 - 0.0068 16.5 0.7 1.1 9.3 0.5 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPS30403.1 - 0.043 13.7 1.5 0.19 11.6 0.2 2.6 2 1 0 2 2 2 0 AAA ATPase domain PolyA_pol_RNAbd PF12627.2 EPS30403.1 - 0.082 12.4 0.0 0.26 10.8 0.0 1.8 1 0 0 1 1 1 0 Probable RNA and SrmB- binding site of polymerase A CDC27 PF09507.5 EPS30403.1 - 1 8.5 5.8 5.6 6.0 0.0 2.2 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Cyclin_N PF00134.18 EPS30406.1 - 2.1e-34 117.8 0.2 5.3e-34 116.5 0.2 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EPS30406.1 - 1.9e-13 50.3 0.2 1.9e-13 50.3 0.1 2.3 3 0 0 3 3 3 1 Cyclin, C-terminal domain WD40 PF00400.27 EPS30410.1 - 5.5e-13 48.2 2.6 0.044 13.6 0.0 8.1 9 0 0 9 9 9 3 WD domain, G-beta repeat PQQ_2 PF13360.1 EPS30410.1 - 1.8e-07 30.9 0.1 0.013 14.9 0.0 4.1 3 2 0 3 3 3 2 PQQ-like domain Yippee-Mis18 PF03226.9 EPS30411.1 - 5.1e-25 87.3 0.5 5.8e-25 87.1 0.3 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.3 EPS30411.1 - 0.01 15.7 1.4 0.022 14.6 1.0 1.5 1 1 0 1 1 1 0 C-terminal domain of RIG-I DUF2039 PF10217.4 EPS30411.1 - 0.014 15.3 0.8 0.086 12.8 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) Evr1_Alr PF04777.8 EPS30411.1 - 0.018 14.9 0.9 0.42 10.5 0.1 2.1 1 1 1 2 2 2 0 Erv1 / Alr family HNH_5 PF14279.1 EPS30411.1 - 0.085 12.8 1.1 3.2 7.8 0.0 2.2 1 1 1 2 2 2 0 HNH endonuclease ADH_N PF08240.7 EPS30412.1 - 6.5e-30 103.1 2.1 1.1e-29 102.3 1.5 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPS30412.1 - 1.9e-18 66.2 0.0 3.6e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EPS30412.1 - 0.027 14.0 0.0 0.059 12.9 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 EPS30412.1 - 0.034 14.1 0.0 0.061 13.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain NADH_4Fe-4S PF10589.4 EPS30412.1 - 0.5 9.5 3.8 1.2 8.3 2.6 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region KH_1 PF00013.24 EPS30413.1 - 4e-39 132.0 8.0 6.4e-15 54.5 0.0 3.1 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EPS30413.1 - 1.3e-29 101.2 10.0 7.8e-11 41.3 0.5 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EPS30413.1 - 2.3e-09 36.6 8.3 0.0018 17.7 0.2 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EPS30413.1 - 4.7e-08 32.5 3.5 0.1 12.2 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EPS30413.1 - 0.00042 20.0 3.4 0.9 9.3 0.0 3.3 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 EPS30413.1 - 0.012 15.1 0.2 0.98 8.8 0.0 3.1 3 0 0 3 3 3 0 dUTPase Toxin-JAB1 PF15659.1 EPS30414.1 - 0.039 13.8 0.5 0.083 12.7 0.4 1.5 1 0 0 1 1 1 0 JAB-like toxin 1 DSPc PF00782.15 EPS30418.1 - 8.7e-23 80.3 0.0 1.1e-20 73.5 0.0 2.2 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Methyltransf_18 PF12847.2 EPS30419.1 - 1.5e-18 67.3 0.0 2.7e-18 66.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPS30419.1 - 4e-13 49.2 0.0 1.5e-07 31.1 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 EPS30419.1 - 1.1e-10 41.4 0.0 1.8e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPS30419.1 - 7.3e-08 32.7 0.0 0.00032 21.1 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EPS30419.1 - 4.2e-06 27.1 0.2 1.8e-05 25.1 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPS30419.1 - 3.5e-05 23.8 0.0 0.00011 22.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPS30419.1 - 0.00016 21.9 0.0 0.00041 20.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EPS30419.1 - 0.018 14.4 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain MetW PF07021.7 EPS30419.1 - 0.02 14.2 0.0 0.06 12.7 0.0 1.7 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW SDA1 PF05285.7 EPS30419.1 - 0.027 13.7 2.8 0.037 13.3 2.0 1.1 1 0 0 1 1 1 0 SDA1 Methyltransf_32 PF13679.1 EPS30419.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EPS30419.1 - 0.16 11.0 0.0 0.81 8.7 0.0 1.8 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Nop14 PF04147.7 EPS30419.1 - 0.17 9.8 3.1 0.24 9.2 2.2 1.2 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 EPS30419.1 - 0.75 9.3 5.4 0.35 10.3 0.3 2.2 2 0 0 2 2 2 0 Nucleoplasmin zf-C2H2_4 PF13894.1 EPS30420.1 - 0.024 14.9 1.2 0.069 13.5 0.8 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EPS30420.1 - 0.23 11.8 3.0 0.66 10.4 2.1 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type Aegerolysin PF06355.8 EPS30422.1 - 1.4e-16 60.5 0.0 2.6e-08 33.7 0.0 2.1 2 0 0 2 2 2 2 Aegerolysin Cytochrom_B561 PF03188.11 EPS30423.1 - 3e-09 36.8 10.0 6.8e-09 35.6 6.9 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 EPS30423.1 - 1.7e-08 33.9 3.0 2.8e-08 33.2 1.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) DUF998 PF06197.8 EPS30423.1 - 0.0029 16.9 14.9 0.0046 16.2 2.1 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF998) Cytochrom_B_N PF00033.14 EPS30423.1 - 0.075 12.3 17.2 0.068 12.5 9.7 2.4 1 1 0 1 1 1 0 Cytochrome b(N-terminal)/b6/petB PgaD PF13994.1 EPS30423.1 - 2 7.8 9.0 2.3 7.7 0.0 2.7 1 1 2 3 3 3 0 PgaD-like protein DUF1129 PF06570.6 EPS30423.1 - 2.5 7.3 6.4 12 5.1 4.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) VSP PF03302.8 EPS30423.1 - 2.8 6.4 5.4 5.6 5.4 3.7 1.4 1 0 0 1 1 1 0 Giardia variant-specific surface protein DUF2306 PF10067.4 EPS30423.1 - 5.8 7.0 12.9 0.45 10.6 1.6 2.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2306) Ni_hydr_CYTB PF01292.15 EPS30423.1 - 8.4 5.7 17.5 16 4.7 5.5 2.9 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 Ribosomal_L24e PF01246.15 EPS30424.1 - 3.4e-26 90.8 3.1 9.7e-26 89.4 2.1 1.8 1 0 0 1 1 1 1 Ribosomal protein L24e Pam16 PF03656.8 EPS30425.1 - 6.2e-08 32.4 0.0 6.8e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.26 EPS30425.1 - 1.4e-07 31.1 0.2 2e-07 30.6 0.1 1.2 1 0 0 1 1 1 1 DnaJ domain Fungal_trans PF04082.13 EPS30427.1 - 1.7e-29 102.5 0.0 3.6e-29 101.4 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS30427.1 - 7e-10 38.6 13.1 1.2e-09 37.8 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 60KD_IMP PF02096.15 EPS30427.1 - 0.31 10.6 0.0 0.31 10.6 0.0 2.7 3 0 0 3 3 3 0 60Kd inner membrane protein OPT PF03169.10 EPS30428.1 - 1.1e-172 575.7 52.4 1.3e-172 575.5 36.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Peptidase_M41 PF01434.13 EPS30429.1 - 1.6e-74 249.9 0.0 3.5e-74 248.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EPS30429.1 - 2.4e-43 147.4 0.0 5.3e-43 146.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 EPS30429.1 - 2.4e-13 50.2 1.0 8.2e-13 48.5 0.0 2.2 2 0 0 2 2 2 1 FtsH Extracellular AAA_5 PF07728.9 EPS30429.1 - 0.00074 19.2 0.0 0.0026 17.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EPS30429.1 - 0.00095 19.3 0.1 0.22 11.6 0.1 2.8 3 0 0 3 3 2 1 AAA domain AAA_17 PF13207.1 EPS30429.1 - 0.0041 17.9 0.0 0.018 15.8 0.0 2.2 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EPS30429.1 - 0.0052 16.5 0.5 0.019 14.7 0.4 1.9 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 EPS30429.1 - 0.0071 15.1 0.1 0.014 14.0 0.1 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 EPS30429.1 - 0.013 15.5 0.2 0.13 12.2 0.1 2.5 1 1 0 2 2 2 0 AAA ATPase domain RuvB_N PF05496.7 EPS30429.1 - 0.013 14.5 0.0 0.037 13.0 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EPS30429.1 - 0.019 14.4 0.1 0.053 12.9 0.1 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 EPS30429.1 - 0.02 15.2 0.2 0.44 10.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 EPS30429.1 - 0.02 14.2 0.4 0.093 12.1 0.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.1 EPS30429.1 - 0.028 14.3 0.0 0.11 12.4 0.0 2.0 2 0 0 2 2 1 0 AAA domain PIH1 PF08190.7 EPS30429.1 - 0.063 12.7 5.9 0.11 11.9 4.1 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 YqfQ PF14181.1 EPS30429.1 - 0.22 11.5 9.1 0.43 10.5 6.3 1.4 1 0 0 1 1 1 0 YqfQ-like protein RR_TM4-6 PF06459.7 EPS30429.1 - 0.87 9.4 7.9 1.4 8.7 5.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Gag_spuma PF03276.9 EPS30429.1 - 1.3 7.2 6.8 64 1.6 0.0 2.6 3 0 0 3 3 3 0 Spumavirus gag protein DUF1295 PF06966.7 EPS30430.1 - 5.1e-43 147.0 11.3 7e-43 146.5 7.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 EPS30430.1 - 0.11 12.7 0.2 0.11 12.7 0.1 3.2 3 1 0 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Topoisom_bac PF01131.15 EPS30431.1 - 2.9e-89 299.7 0.0 3.5e-89 299.4 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 EPS30431.1 - 4.6e-19 68.2 0.0 1.1e-18 67.0 0.0 1.7 1 0 0 1 1 1 1 Toprim domain PX PF00787.19 EPS30435.1 - 2.4e-15 56.2 0.1 5.2e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 PX domain SNARE PF05739.14 EPS30435.1 - 1.1e-05 25.0 5.4 1.1e-05 25.0 3.7 2.0 2 0 0 2 2 2 1 SNARE domain BCIP PF13862.1 EPS30435.1 - 0.025 14.1 0.4 0.043 13.3 0.3 1.4 1 0 0 1 1 1 0 p21-C-terminal region-binding protein Ku PF02735.11 EPS30436.1 - 6.4e-27 94.2 0.0 1.6e-26 92.9 0.0 1.6 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EPS30436.1 - 3.2e-19 69.2 0.0 5.2e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind PF08785.6 EPS30436.1 - 6.7e-15 55.0 0.0 1.6e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 Ku C terminal domain like VWA_2 PF13519.1 EPS30436.1 - 3.7e-05 23.8 0.0 8.2e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF4149 PF13664.1 EPS30437.1 - 3.2e-26 91.3 3.3 6.6e-26 90.3 1.6 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) tRNA-synt_2 PF00152.15 EPS30438.1 - 1.3e-75 254.2 0.2 1.8e-75 253.8 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EPS30438.1 - 2.8e-06 27.0 0.1 4.9e-06 26.3 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Hydrolase_6 PF13344.1 EPS30439.1 - 1e-24 86.3 0.0 2e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EPS30439.1 - 7.4e-17 60.8 0.0 1.1e-15 57.1 0.0 2.6 3 0 0 3 3 3 1 HAD-hyrolase-like HAD_2 PF13419.1 EPS30439.1 - 5.8e-06 26.6 0.0 0.028 14.6 0.0 3.6 2 1 2 4 4 4 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPS30439.1 - 0.00044 20.7 0.0 0.58 10.5 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase F-box-like PF12937.2 EPS30440.1 - 5.6e-06 25.9 0.7 2.3e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 F-box-like Adaptin_N PF01602.15 EPS30441.1 - 1.2e-112 376.9 0.4 1.6e-112 376.5 0.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EPS30441.1 - 1.9e-59 199.7 1.1 5.3e-59 198.3 0.7 1.8 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EPS30441.1 - 3.7e-15 55.9 0.6 2.3e-05 24.6 0.0 6.2 2 2 4 6 6 6 4 HEAT repeats HEAT PF02985.17 EPS30441.1 - 0.0011 18.8 6.5 2.9 8.2 0.1 5.7 6 0 0 6 6 6 1 HEAT repeat HEAT_PBS PF03130.11 EPS30441.1 - 0.0072 16.6 5.5 4.8 7.9 0.0 5.3 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 EPS30441.1 - 0.058 13.9 3.5 0.27 11.7 0.3 3.5 3 0 0 3 3 3 0 HEAT-like repeat Cnd1 PF12717.2 EPS30441.1 - 0.068 13.0 8.0 0.38 10.5 0.2 4.1 4 1 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Phosducin PF02114.11 EPS30442.1 - 1.1e-12 47.2 0.1 1.4e-12 46.9 0.1 1.2 1 0 0 1 1 1 1 Phosducin bZIP_1 PF00170.16 EPS30443.1 - 1.6e-09 37.6 11.4 2.7e-09 36.8 7.9 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EPS30443.1 - 3.9e-05 23.3 8.2 3.9e-05 23.3 5.7 1.6 2 0 0 2 2 1 1 Basic region leucine zipper PGBA_C PF15437.1 EPS30443.1 - 0.00022 21.2 7.1 0.00053 20.0 4.9 1.6 1 0 0 1 1 1 1 Plasminogen-binding protein pgbA C-terminal bZIP_Maf PF03131.12 EPS30443.1 - 0.0091 16.2 9.0 0.014 15.6 6.3 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF972 PF06156.8 EPS30443.1 - 0.014 15.7 0.3 0.014 15.7 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF972) MIS13 PF08202.6 EPS30443.1 - 0.021 13.9 5.1 0.028 13.4 3.5 1.1 1 0 0 1 1 1 0 Mis12-Mtw1 protein family ADIP PF11559.3 EPS30443.1 - 0.024 14.5 4.9 0.024 14.5 3.4 1.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.14 EPS30443.1 - 0.038 11.8 0.7 0.048 11.5 0.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CCDC155 PF14662.1 EPS30443.1 - 0.045 13.3 6.1 0.065 12.8 4.2 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 GAS PF13851.1 EPS30443.1 - 0.1 11.8 5.3 0.15 11.2 3.6 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DivIC PF04977.10 EPS30443.1 - 0.1 12.1 3.1 0.19 11.2 2.2 1.5 1 0 0 1 1 1 0 Septum formation initiator Glutaredoxin2_C PF04399.8 EPS30443.1 - 0.18 11.3 1.7 0.34 10.4 1.2 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain DUF724 PF05266.9 EPS30443.1 - 0.35 10.4 5.2 0.57 9.7 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF904 PF06005.7 EPS30443.1 - 1.3 9.3 6.0 0.14 12.4 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Bap31 PF05529.7 EPS30443.1 - 4.3 6.7 5.0 6.5 6.1 3.5 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Pkinase PF00069.20 EPS30444.1 - 2.3e-38 131.8 0.0 2.9e-38 131.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS30444.1 - 7.6e-14 51.3 0.0 1.1e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPS30444.1 - 1.6e-05 24.7 0.2 0.0015 18.3 0.0 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kelch_3 PF13415.1 EPS30445.1 - 1.3e-38 130.2 12.1 1e-08 35.0 0.1 6.0 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.1 EPS30445.1 - 2.2e-34 116.9 11.0 3.5e-08 33.1 0.7 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 EPS30445.1 - 3.3e-34 116.2 1.8 5.4e-08 32.6 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.20 EPS30445.1 - 5e-30 102.8 0.1 3.2e-09 36.1 0.1 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 EPS30445.1 - 1e-26 91.9 7.5 2.5e-10 40.0 0.2 6.4 4 1 2 6 6 6 5 Kelch motif Kelch_2 PF07646.10 EPS30445.1 - 6.6e-23 79.5 3.6 4.2e-10 38.9 0.1 6.6 6 0 0 6 6 6 4 Kelch motif RAG2 PF03089.9 EPS30445.1 - 0.013 14.2 0.0 0.53 8.9 0.0 3.1 4 1 0 4 4 4 0 Recombination activating protein 2 Raptor_N PF14538.1 EPS30447.1 - 1.9e-63 212.9 0.0 3.7e-63 211.9 0.0 1.5 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 EPS30447.1 - 1.5e-06 27.8 5.5 0.27 11.1 0.0 6.0 6 0 0 6 6 6 1 WD domain, G-beta repeat Peptidase_C14 PF00656.17 EPS30447.1 - 0.0011 18.6 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 Caspase domain BBS2_Mid PF14783.1 EPS30447.1 - 0.0024 17.6 0.6 0.52 10.0 0.1 3.0 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region HEAT PF02985.17 EPS30447.1 - 0.023 14.7 0.1 23 5.4 0.1 3.5 3 0 0 3 3 3 0 HEAT repeat zf-RING_2 PF13639.1 EPS30449.1 - 4.5e-14 51.9 5.8 7.3e-14 51.3 4.0 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 EPS30449.1 - 1.7e-12 46.8 0.0 4.1e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.1 EPS30449.1 - 2e-09 37.2 5.2 3.4e-09 36.5 3.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EPS30449.1 - 4.8e-09 36.1 1.8 8.7e-09 35.3 1.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EPS30449.1 - 1.2e-08 34.4 3.6 1.9e-08 33.8 2.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPS30449.1 - 3.3e-08 33.0 3.2 5e-08 32.4 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPS30449.1 - 1.2e-07 31.3 2.8 1.9e-07 30.7 2.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EPS30449.1 - 0.00044 20.0 0.3 0.00084 19.1 0.2 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EPS30449.1 - 0.016 14.9 2.9 0.037 13.7 2.0 1.7 1 0 0 1 1 1 0 RING-type zinc-finger RINGv PF12906.2 EPS30449.1 - 0.056 13.5 4.2 0.099 12.7 2.9 1.4 1 0 0 1 1 1 0 RING-variant domain FANCL_C PF11793.3 EPS30449.1 - 0.057 13.3 2.7 0.14 12.1 1.9 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 EPS30449.1 - 0.078 12.8 3.6 0.23 11.3 2.6 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EPS30449.1 - 0.36 10.4 3.0 0.64 9.6 2.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.24 EPS30449.1 - 0.69 9.6 3.0 1.2 8.8 2.1 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 EPS30449.1 - 2.3 8.2 3.8 4.2 7.4 2.7 1.4 1 0 0 1 1 1 0 RING-like domain FHA PF00498.21 EPS30450.1 - 7.2e-16 58.0 0.0 1.6e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 FHA domain ERM PF00769.14 EPS30450.1 - 0.026 14.0 31.0 0.062 12.8 9.2 3.4 2 1 0 3 3 3 0 Ezrin/radixin/moesin family EzrA PF06160.7 EPS30450.1 - 1.6 6.8 21.7 0.09 10.9 11.0 1.6 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA DUF972 PF06156.8 EPS30450.1 - 1.9 8.8 21.1 0.026 14.8 5.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF972) TBPIP PF07106.8 EPS30450.1 - 4.1 6.9 20.7 0.46 10.0 4.2 3.2 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Atg14 PF10186.4 EPS30450.1 - 5 5.9 20.5 1.2 8.0 4.4 2.6 2 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 CENP-Q PF13094.1 EPS30450.1 - 5.7 6.9 37.4 1.1 9.2 6.0 3.9 3 1 1 4 4 4 0 CENP-Q, a CENPA-CAD centromere complex subunit Romo1 PF10247.4 EPS30451.1 - 2.5e-29 101.2 13.4 3.1e-29 100.9 9.3 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 LRR_8 PF13855.1 EPS30454.1 - 8.2e-15 54.3 12.8 5.5e-09 35.6 3.3 3.6 3 1 1 4 4 4 2 Leucine rich repeat LRR_4 PF12799.2 EPS30454.1 - 1.8e-11 43.3 12.5 1.1e-07 31.2 1.2 4.3 3 2 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPS30454.1 - 3.5e-05 23.2 11.9 0.3 11.2 0.1 5.6 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 EPS30454.1 - 9.5e-05 21.9 5.6 4.5 7.9 0.1 4.8 4 0 0 4 4 4 2 Leucine rich repeat LRR_9 PF14580.1 EPS30454.1 - 0.00041 19.9 0.1 0.0007 19.1 0.1 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.1 EPS30454.1 - 0.0024 17.7 2.2 7.3 7.0 0.0 4.0 4 0 0 4 4 4 1 Leucine Rich repeat Rpp20 PF12328.3 EPS30455.1 - 2.8e-50 169.7 13.8 4.8e-50 168.9 9.6 1.4 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 EPS30455.1 - 1e-23 82.6 1.4 1.8e-23 81.8 1.0 1.4 1 0 0 1 1 1 1 Alba WHIM3 PF15614.1 EPS30455.1 - 0.078 12.7 0.4 0.14 11.9 0.0 1.7 2 0 0 2 2 2 0 WSTF, HB1, Itc1p, MBD9 motif 3 DUF2786 PF10979.3 EPS30455.1 - 0.14 11.8 0.4 0.14 11.8 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2786) NUP50 PF08911.6 EPS30455.1 - 0.17 12.2 3.3 0.71 10.2 2.3 2.2 1 1 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) UDP-g_GGTase PF06427.6 EPS30459.1 - 3.3e-68 229.1 0.0 6.6e-68 228.1 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 EPS30459.1 - 0.00057 19.2 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Myb_DNA-binding PF00249.26 EPS30460.1 - 1.3e-14 53.9 1.5 2.4e-08 33.8 0.1 2.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EPS30460.1 - 4.1e-14 52.4 7.4 8.2e-11 41.8 0.1 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain HSP70 PF00012.15 EPS30462.1 - 2.4e-87 293.2 0.9 2.4e-87 293.2 0.6 1.3 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EPS30462.1 - 8.4e-11 41.0 0.2 1.2e-10 40.4 0.2 1.3 1 0 0 1 1 1 1 MreB/Mbl protein Peripla_BP_6 PF13458.1 EPS30462.1 - 0.009 15.4 0.6 0.22 10.8 0.2 2.3 2 0 0 2 2 2 1 Periplasmic binding protein SUR7 PF06687.7 EPS30463.1 - 2.5e-38 131.7 6.6 2.9e-38 131.5 4.6 1.0 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EPS30463.1 - 9.8e-05 22.1 8.0 9.8e-05 22.1 5.5 1.9 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Amastin PF07344.6 EPS30463.1 - 0.0071 15.9 6.5 0.0071 15.9 4.5 1.9 2 1 0 2 2 2 1 Amastin surface glycoprotein Clc-like PF07062.7 EPS30463.1 - 0.03 13.5 3.1 0.051 12.8 2.1 1.4 1 0 0 1 1 1 0 Clc-like Fig1 PF12351.3 EPS30463.1 - 0.21 11.4 11.8 0.22 11.4 7.2 1.6 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 DUF4491 PF14898.1 EPS30463.1 - 0.53 10.4 3.1 1.3 9.2 0.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4491) Rogdi_lz PF10259.4 EPS30464.1 - 6.1e-75 251.8 0.0 7e-75 251.6 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Rsm22 PF09243.5 EPS30465.1 - 4.2e-33 114.5 0.0 1.7e-30 106.0 0.0 2.9 2 1 0 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 DASH_Spc19 PF08287.6 EPS30466.1 - 8.9e-52 174.7 6.9 1.2e-51 174.4 4.8 1.1 1 0 0 1 1 1 1 Spc19 Mur_ligase_M PF08245.7 EPS30466.1 - 0.13 12.3 0.0 0.17 11.8 0.0 1.4 1 1 0 1 1 1 0 Mur ligase middle domain COG5 PF10392.4 EPS30466.1 - 1.1 9.1 9.1 1.5 8.7 0.3 3.0 2 1 1 3 3 3 0 Golgi transport complex subunit 5 IFP_35_N PF07334.8 EPS30466.1 - 6.7 6.7 7.1 7.1 6.6 1.3 2.8 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus ATP-synt_J PF04911.7 EPS30467.1 - 8.5e-23 79.5 0.1 9.1e-23 79.4 0.1 1.0 1 0 0 1 1 1 1 ATP synthase j chain HNH_2 PF13391.1 EPS30468.1 - 1.7e-08 34.1 0.0 2.6e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 HNH endonuclease EF-hand_1 PF00036.27 EPS30469.1 - 2e-12 45.4 5.3 1.9e-05 23.6 0.2 3.4 3 0 0 3 3 3 2 EF hand ZZ PF00569.12 EPS30469.1 - 7.6e-11 41.3 4.9 7.6e-11 41.3 3.4 1.6 2 0 0 2 2 2 1 Zinc finger, ZZ type EF-hand_7 PF13499.1 EPS30469.1 - 1.3e-10 41.2 3.9 3.4e-10 39.9 1.9 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EPS30469.1 - 1.8e-09 36.7 3.5 0.00017 21.1 0.1 3.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.1 EPS30469.1 - 8.3e-07 28.5 6.4 0.0073 15.9 0.1 3.2 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 EPS30469.1 - 0.00081 18.6 5.9 0.26 10.7 0.2 3.3 3 0 0 3 3 3 2 EF hand APG6 PF04111.7 EPS30469.1 - 0.58 9.1 0.6 4.2 6.3 0.3 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 C1_3 PF07649.7 EPS30469.1 - 1.2 9.1 6.5 2 8.5 4.5 1.3 1 0 0 1 1 1 0 C1-like domain MFS_1 PF07690.11 EPS30470.1 - 3.2e-44 151.0 55.6 3.2e-44 151.0 38.5 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS30470.1 - 2.1e-16 59.5 5.9 2.1e-16 59.5 4.1 3.1 2 1 0 3 3 3 1 Sugar (and other) transporter DUF2752 PF10825.3 EPS30470.1 - 0.0051 16.8 1.1 0.035 14.1 0.7 2.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2752) Meth_synt_2 PF01717.13 EPS30471.1 - 1.3e-12 47.3 0.0 2.1e-10 40.1 0.0 2.4 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EPS30471.1 - 0.00019 20.8 0.0 0.022 14.0 0.0 3.0 3 1 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain Peptidase_M24 PF00557.19 EPS30472.1 - 1.3e-43 149.0 0.1 1.7e-43 148.6 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 EPS30472.1 - 0.00047 19.9 4.5 0.00047 19.9 3.1 2.4 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.11 EPS30472.1 - 0.28 10.8 3.3 0.58 9.8 2.3 1.6 1 0 0 1 1 1 0 HIT zinc finger FAD_binding_3 PF01494.14 EPS30473.1 - 3.5e-13 49.3 0.0 1.4e-12 47.3 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EPS30473.1 - 5.6e-06 26.6 0.0 0.00014 22.2 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPS30473.1 - 0.00034 20.5 1.1 0.0016 18.4 0.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EPS30473.1 - 0.00098 18.1 0.8 0.0026 16.7 0.3 1.7 1 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EPS30473.1 - 0.0011 17.5 0.1 0.0016 17.0 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 EPS30473.1 - 0.0015 18.4 0.1 0.003 17.4 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EPS30473.1 - 0.0055 15.8 1.5 0.0055 15.8 1.0 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 EPS30473.1 - 0.0082 15.0 0.1 0.02 13.7 0.1 1.6 1 1 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EPS30473.1 - 0.15 10.8 0.1 0.28 10.0 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain WD40 PF00400.27 EPS30474.1 - 4.7e-40 134.0 8.1 2.7e-10 39.7 0.0 7.5 7 1 0 7 7 7 5 WD domain, G-beta repeat PQQ_2 PF13360.1 EPS30474.1 - 0.0024 17.3 0.0 0.017 14.5 0.0 2.3 1 1 0 1 1 1 1 PQQ-like domain Cornichon PF03311.9 EPS30475.1 - 1.9e-53 179.9 12.3 2.2e-53 179.7 8.6 1.0 1 0 0 1 1 1 1 Cornichon protein DUF1634 PF07843.6 EPS30475.1 - 0.14 11.7 0.2 0.14 11.7 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1634) ABC2_membrane PF01061.19 EPS30476.1 - 2.2e-35 121.7 22.2 2.2e-35 121.7 15.4 1.8 2 0 0 2 2 1 1 ABC-2 type transporter ABC_tran PF00005.22 EPS30476.1 - 4.3e-24 85.3 0.4 9.4e-24 84.2 0.0 1.8 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EPS30476.1 - 3.8e-09 36.9 0.0 2.1e-08 34.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain hEGF PF12661.2 EPS30476.1 - 5.7e-05 22.9 21.6 0.025 14.6 1.5 4.3 3 0 0 3 3 3 2 Human growth factor-like EGF ABC2_membrane_3 PF12698.2 EPS30476.1 - 6e-05 22.2 28.5 0.00025 20.1 20.0 1.9 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_25 PF13481.1 EPS30476.1 - 0.0011 18.4 0.1 0.13 11.6 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EPS30476.1 - 0.0025 17.9 0.0 0.0057 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPS30476.1 - 0.0028 17.6 0.0 0.0052 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 EPS30476.1 - 0.0082 15.6 0.2 0.019 14.4 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EPS30476.1 - 0.022 15.5 0.0 0.057 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EPS30476.1 - 0.031 13.4 0.0 0.056 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EPS30476.1 - 0.033 13.8 0.0 0.055 13.1 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase AAA_23 PF13476.1 EPS30476.1 - 0.047 14.0 1.8 0.15 12.3 0.5 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EPS30476.1 - 0.07 13.0 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EPS30476.1 - 0.092 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EPS30476.1 - 0.099 12.9 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 EPS30476.1 - 0.12 11.3 0.0 3.2 6.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.1 EPS30476.1 - 0.16 11.9 0.1 0.32 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EPS30476.1 - 0.18 11.4 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ArgK PF03308.11 EPS30476.1 - 0.2 10.3 0.0 0.33 9.6 0.0 1.2 1 0 0 1 1 1 0 ArgK protein cobW PF02492.14 EPS30476.1 - 0.22 10.9 0.0 0.36 10.2 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF3827 PF12877.2 EPS30476.1 - 0.29 9.2 4.5 7 4.6 2.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3827) DUF1212 PF06738.7 EPS30476.1 - 0.29 10.5 4.5 0.9 8.9 3.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) Aminotran_1_2 PF00155.16 EPS30477.1 - 4.2e-41 141.0 0.0 5.2e-41 140.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EPS30477.1 - 7.1e-08 31.9 0.0 1e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EPS30477.1 - 2.7e-07 29.2 0.0 3.8e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EPS30477.1 - 2e-06 26.7 0.0 3.2e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_MocR PF12897.2 EPS30477.1 - 6.1e-06 25.0 0.0 8.1e-06 24.6 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.12 EPS30477.1 - 8.1e-05 21.8 0.0 0.00012 21.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family AMP-binding PF00501.23 EPS30478.1 - 1.1e-64 218.4 0.0 1.5e-64 217.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPS30478.1 - 3.6e-11 43.8 0.0 9.2e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SCRG1 PF15224.1 EPS30478.1 - 0.16 11.8 0.0 0.33 10.7 0.0 1.4 1 0 0 1 1 1 0 Scrapie-responsive protein 1 Fungal_trans PF04082.13 EPS30479.1 - 7.5e-17 61.0 2.0 8.1e-17 60.9 0.3 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS30479.1 - 0.0028 17.5 2.6 0.0057 16.5 1.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MerC PF03203.9 EPS30479.1 - 0.14 12.4 0.1 0.27 11.6 0.1 1.4 1 0 0 1 1 1 0 MerC mercury resistance protein Polyketide_cyc PF03364.15 EPS30480.1 - 1.2e-22 80.2 0.0 5.8e-22 78.0 0.0 1.8 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 EPS30480.1 - 0.00098 19.3 0.0 1 9.5 0.0 2.1 2 0 0 2 2 2 2 Polyketide cyclase / dehydrase and lipid transport Sod_Fe_C PF02777.13 EPS30481.1 - 8.5e-15 54.4 0.4 6.6e-08 32.3 0.5 2.4 1 1 1 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EPS30481.1 - 0.029 14.6 0.1 0.047 13.9 0.1 1.4 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, alpha-hairpin domain Integrase_Zn PF02022.14 EPS30481.1 - 0.14 11.6 0.0 0.36 10.3 0.0 1.6 1 0 0 1 1 1 0 Integrase Zinc binding domain Granulin PF00396.13 EPS30482.1 - 7.9 6.6 27.3 2.7 8.1 3.3 3.5 2 1 0 2 2 2 0 Granulin PIG-S PF10510.4 EPS30483.1 - 8.2e-177 588.9 0.0 9.4e-177 588.7 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein FimP PF09766.4 EPS30484.1 - 2.4e-26 92.6 12.5 2.8e-26 92.4 8.6 1.1 1 0 0 1 1 1 1 Fms-interacting protein DUF4200 PF13863.1 EPS30484.1 - 0.00018 21.4 13.8 0.04 13.8 0.9 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4200) DUF972 PF06156.8 EPS30484.1 - 0.059 13.7 7.7 3 8.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF972) K-box PF01486.12 EPS30484.1 - 0.13 12.1 0.4 0.13 12.1 0.3 3.2 2 2 1 3 3 3 0 K-box region Cortex-I_coil PF09304.5 EPS30484.1 - 0.14 12.2 12.0 0.95 9.5 0.6 2.2 2 0 0 2 2 2 0 Cortexillin I, coiled coil DUF4140 PF13600.1 EPS30484.1 - 0.4 11.1 9.4 0.48 10.9 0.3 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) RNase_E_G PF10150.4 EPS30484.1 - 1.8 7.7 6.3 0.46 9.6 1.4 1.9 2 0 0 2 2 2 0 Ribonuclease E/G family Atg14 PF10186.4 EPS30484.1 - 1.9 7.3 9.3 0.92 8.3 4.0 1.8 1 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Pinin_SDK_memA PF04696.8 EPS30484.1 - 2.3 7.8 9.8 1.2 8.7 3.7 2.1 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region DUF349 PF03993.7 EPS30484.1 - 2.8 8.1 9.3 0.41 10.8 3.3 1.9 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) DivIC PF04977.10 EPS30484.1 - 3 7.3 13.5 1.2 8.6 0.2 3.1 2 1 1 3 3 3 0 Septum formation initiator HlyIII PF03006.15 EPS30485.1 - 1.8e-57 194.2 24.6 2.3e-57 193.9 17.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related SPC12 PF06645.8 EPS30485.1 - 0.005 16.6 0.5 0.018 14.8 0.3 1.9 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF373 PF04123.8 EPS30485.1 - 0.1 11.5 3.0 0.17 10.8 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Methyltransf_12 PF08242.7 EPS30486.1 - 4.1e-13 49.6 0.0 1.2e-12 48.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPS30486.1 - 1.6e-12 47.4 0.0 4.1e-12 46.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPS30486.1 - 1.1e-11 45.0 0.0 3.6e-11 43.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPS30486.1 - 9.4e-11 41.9 0.0 2e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS30486.1 - 7.7e-09 36.1 0.0 5.3e-08 33.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPS30486.1 - 7.8e-08 32.3 0.0 1.5e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPS30486.1 - 1.6e-07 30.7 0.0 2.3e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EPS30486.1 - 2.9e-07 30.2 0.0 5e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 EPS30486.1 - 0.00072 20.3 0.0 0.0023 18.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain DUF3419 PF11899.3 EPS30486.1 - 0.0009 18.0 0.0 0.0017 17.1 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3419) MTS PF05175.9 EPS30486.1 - 0.0015 17.8 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.12 EPS30486.1 - 0.0036 16.2 0.0 0.21 10.5 0.0 2.2 1 1 1 2 2 2 1 NNMT/PNMT/TEMT family Methyltransf_8 PF05148.10 EPS30486.1 - 0.017 14.7 0.0 0.36 10.4 0.0 2.2 1 1 0 1 1 1 0 Hypothetical methyltransferase Herpes_LMP2 PF07415.6 EPS30487.1 - 1.4 7.3 3.9 1.8 7.0 2.7 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein CS PF04969.11 EPS30488.1 - 4.3e-18 65.6 0.0 9.6e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 CS domain Diphthamide_syn PF01866.12 EPS30492.1 - 7.4e-53 179.7 0.0 1.9e-52 178.4 0.0 1.6 2 0 0 2 2 2 1 Putative diphthamide synthesis protein WD40 PF00400.27 EPS30493.1 - 1.4e-07 31.0 0.4 0.00055 19.7 0.0 4.6 4 1 0 4 4 4 2 WD domain, G-beta repeat DUF3245 PF11595.3 EPS30493.1 - 0.91 9.7 8.1 0.42 10.8 1.7 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3245) Glyco_hydro_7 PF00840.15 EPS30494.1 - 1.8e-213 708.6 22.4 2.1e-213 708.4 15.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Abhydrolase_6 PF12697.2 EPS30495.1 - 7.5e-20 71.7 1.0 5.9e-19 68.8 0.7 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPS30495.1 - 7.9e-10 38.6 0.2 2.2e-09 37.2 0.1 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPS30495.1 - 8.7e-09 35.2 0.4 6.8e-08 32.3 0.3 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 EPS30495.1 - 1.1e-07 31.3 0.4 0.0023 17.2 0.0 3.1 3 0 0 3 3 3 3 Dienelactone hydrolase family Hydrolase_4 PF12146.3 EPS30495.1 - 8.9e-05 22.2 0.0 0.00025 20.8 0.0 1.8 1 0 0 1 1 1 1 Putative lysophospholipase DUF2048 PF09752.4 EPS30495.1 - 0.24 10.2 1.6 0.28 10.0 0.3 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) Aldedh PF00171.17 EPS30496.1 - 0.019 13.3 0.0 0.021 13.1 0.0 1.0 1 0 0 1 1 1 0 Aldehyde dehydrogenase family Abhydrolase_3 PF07859.8 EPS30497.1 - 8.9e-38 129.9 0.0 1.1e-37 129.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EPS30497.1 - 2.4e-06 26.5 0.2 1.5e-05 23.9 0.1 1.8 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 EPS30497.1 - 3.4e-05 23.1 0.0 0.0036 16.5 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EPS30497.1 - 0.00023 21.1 0.0 0.0022 17.9 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPS30497.1 - 0.00031 20.5 0.0 0.00042 20.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EPS30497.1 - 0.002 17.0 0.0 0.0029 16.5 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EPS30497.1 - 0.0028 16.4 0.0 0.0055 15.5 0.0 1.5 1 1 0 1 1 1 1 Chlorophyllase Abhydrolase_2 PF02230.11 EPS30497.1 - 0.012 15.0 0.0 0.025 14.0 0.0 1.5 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DLH PF01738.13 EPS30497.1 - 0.013 14.7 0.0 0.54 9.4 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 EPS30497.1 - 0.021 14.3 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Esterase_phd PF10503.4 EPS30497.1 - 0.032 13.4 0.0 0.053 12.7 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase BAAT_C PF08840.6 EPS30497.1 - 0.046 13.4 0.0 0.064 12.9 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2974 PF11187.3 EPS30497.1 - 0.054 12.8 0.0 0.08 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) AXE1 PF05448.7 EPS30497.1 - 0.088 11.2 0.0 0.31 9.5 0.0 1.7 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) APG5 PF04106.7 EPS30498.1 - 3.7e-67 225.6 0.0 4.8e-67 225.2 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 Ank_2 PF12796.2 EPS30499.1 - 3.4e-68 225.9 29.3 3e-19 69.1 0.4 6.6 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EPS30499.1 - 1.5e-59 194.9 24.3 6.7e-09 35.1 0.1 12.8 12 1 0 12 12 12 10 Ankyrin repeat Ank_4 PF13637.1 EPS30499.1 - 2.6e-52 174.2 20.8 2.2e-09 37.5 0.0 11.4 4 4 7 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPS30499.1 - 3.9e-49 159.6 16.3 4.2e-05 23.3 0.1 13.1 13 0 0 13 13 12 10 Ankyrin repeat Ank_5 PF13857.1 EPS30499.1 - 8.5e-41 137.0 16.8 9.5e-09 35.2 0.2 8.0 6 1 2 8 8 8 6 Ankyrin repeats (many copies) AAA_22 PF13401.1 EPS30499.1 - 1.2e-09 38.3 0.0 4.2e-09 36.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EPS30499.1 - 5.8e-08 32.5 0.1 2.7e-07 30.4 0.0 2.3 2 0 0 2 2 2 1 NACHT domain NB-ARC PF00931.17 EPS30499.1 - 1.2e-06 27.5 0.0 2.2e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 EPS30499.1 - 1e-05 25.6 0.1 4.9e-05 23.3 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 EPS30499.1 - 0.00047 20.0 0.0 0.071 13.0 0.0 2.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EPS30499.1 - 0.00082 19.2 0.1 0.0038 17.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EPS30499.1 - 0.00096 19.3 0.0 0.0031 17.7 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EPS30499.1 - 0.004 16.8 0.0 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase SAM_2 PF07647.12 EPS30500.1 - 5.2e-13 48.6 0.1 1.2e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EPS30500.1 - 4.7e-12 45.9 0.1 9.1e-12 44.9 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.24 EPS30500.1 - 0.0001 22.4 0.0 0.00026 21.1 0.0 1.8 1 0 0 1 1 1 1 PH domain Ste50p-SAM PF09235.5 EPS30500.1 - 0.00027 20.9 0.0 0.00051 20.0 0.0 1.5 1 0 0 1 1 1 1 Ste50p, sterile alpha motif PH_9 PF15410.1 EPS30500.1 - 0.083 13.0 0.4 0.22 11.6 0.1 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain Fungal_trans_2 PF11951.3 EPS30502.1 - 1.3e-85 287.3 0.7 1.6e-85 286.9 0.5 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS30502.1 - 3.3e-07 30.0 8.3 6.4e-07 29.1 5.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF569 PF04601.8 EPS30504.1 - 0.016 14.6 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF569) SHR3_chaperone PF08229.6 EPS30505.1 - 2.6e-79 264.7 0.0 3.2e-79 264.4 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 Tad PF13400.1 EPS30505.1 - 1.3 9.0 8.5 0.16 12.0 2.3 2.2 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like Arrestin_N PF00339.24 EPS30506.1 - 4.6e-14 52.4 0.0 1.6e-12 47.5 0.0 2.9 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EPS30506.1 - 1.4e-08 34.9 1.1 4.4e-06 26.8 0.0 2.7 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain CytochromB561_N PF09786.4 EPS30506.1 - 9.5 4.5 7.0 45 2.2 0.0 2.1 2 0 0 2 2 2 0 Cytochrome B561, N terminal Mnd1 PF03962.10 EPS30507.1 - 8.5e-48 162.5 1.1 1e-47 162.2 0.8 1.1 1 0 0 1 1 1 1 Mnd1 family UBA_e1_C PF09358.5 EPS30507.1 - 0.033 14.3 0.0 0.048 13.8 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-activating enzyme e1 C-terminal domain UAF_Rrn10 PF05234.6 EPS30508.1 - 0.00041 20.3 0.0 0.00088 19.2 0.0 1.6 1 1 0 1 1 1 1 UAF complex subunit Rrn10 DUF1195 PF06708.6 EPS30508.1 - 0.049 13.0 0.0 0.094 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1195) Pterin_4a PF01329.14 EPS30508.1 - 0.057 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Pterin 4 alpha carbinolamine dehydratase MRI PF15325.1 EPS30508.1 - 0.075 14.0 1.0 0.16 12.9 0.3 1.8 1 1 0 1 1 1 0 Modulator of retrovirus infection WD40 PF00400.27 EPS30509.1 - 4.5e-34 115.1 17.8 2.3e-08 33.6 0.0 5.7 6 0 0 6 6 6 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EPS30509.1 - 0.0019 17.0 0.1 1.3 7.6 0.0 2.8 2 1 0 3 3 3 2 Nup133 N terminal like MFS_1 PF07690.11 EPS30513.1 - 4.4e-32 111.1 44.0 4.4e-32 111.1 30.5 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPS30513.1 - 1.7e-17 62.8 25.3 2.2e-17 62.5 17.5 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EPS30513.1 - 1.8e-11 43.3 13.0 1.8e-11 43.3 9.0 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_3 PF05977.8 EPS30513.1 - 0.00046 18.4 5.3 0.00046 18.4 3.6 2.7 2 0 0 2 2 2 1 Transmembrane secretion effector Zip PF02535.17 EPS30514.1 - 5.6e-38 130.7 11.7 5.6e-38 130.7 8.1 2.1 2 0 0 2 2 2 2 ZIP Zinc transporter Glycophorin_A PF01102.13 EPS30514.1 - 0.07 12.8 0.1 0.35 10.6 0.0 2.2 2 0 0 2 2 2 0 Glycophorin A VWA_3 PF13768.1 EPS30515.1 - 9.2e-28 96.8 0.0 1.7e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 EPS30515.1 - 6.2e-18 64.6 0.0 1.1e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 EPS30515.1 - 7.7e-15 55.4 0.0 1.6e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EPS30515.1 - 3.3e-13 49.7 0.0 5.7e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 EPS30515.1 - 0.00022 20.4 0.0 0.00036 19.7 0.0 1.2 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein NIR_SIR_ferr PF03460.12 EPS30516.1 - 0.091 12.4 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 Nitrite/Sulfite reductase ferredoxin-like half domain Pox_A28 PF04584.9 EPS30516.1 - 0.13 12.1 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A28 family Pyr_redox_3 PF13738.1 EPS30518.1 - 2.9e-22 79.7 0.0 4.6e-21 75.8 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EPS30518.1 - 3.6e-12 45.2 0.2 3.8e-09 35.2 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EPS30518.1 - 2.3e-10 40.7 0.0 7e-09 35.8 0.0 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EPS30518.1 - 2.7e-09 36.4 0.2 4.3e-07 29.1 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EPS30518.1 - 7.2e-07 29.1 0.0 3.5e-06 26.9 0.0 2.3 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EPS30518.1 - 2e-05 23.8 0.0 7.7e-05 21.8 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EPS30518.1 - 3e-05 24.3 0.2 0.68 10.3 0.0 3.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EPS30518.1 - 0.00043 19.2 0.6 0.00092 18.1 0.3 1.6 2 0 0 2 2 2 1 FAD binding domain 2-Hacid_dh_C PF02826.14 EPS30518.1 - 0.00088 18.4 0.1 0.084 12.0 0.1 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.12 EPS30518.1 - 0.0015 17.6 0.0 0.28 10.2 0.0 2.4 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 EPS30518.1 - 0.004 15.6 0.2 0.012 14.1 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 EPS30518.1 - 0.0045 15.8 0.8 0.29 9.9 0.1 2.6 3 0 0 3 3 3 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 EPS30518.1 - 0.0065 16.1 0.1 0.35 10.5 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IlvN PF07991.7 EPS30518.1 - 0.0098 15.2 0.1 0.76 9.1 0.0 2.4 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_9 PF13454.1 EPS30518.1 - 0.01 15.5 0.3 4.6 7.0 0.0 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding DAO PF01266.19 EPS30518.1 - 0.016 14.1 2.0 0.44 9.4 1.0 2.7 2 1 0 2 2 2 0 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EPS30518.1 - 0.02 13.9 0.7 0.4 9.6 0.5 2.1 1 1 0 1 1 1 0 FAD dependent oxidoreductase SnoaL_2 PF12680.2 EPS30518.1 - 0.052 13.9 0.1 0.76 10.2 0.0 2.8 3 0 0 3 3 2 0 SnoaL-like domain Gp23 PF07068.6 EPS30520.1 - 0.27 9.7 9.0 0.37 9.2 6.2 1.1 1 0 0 1 1 1 0 Major capsid protein Gp23 Sugar_tr PF00083.19 EPS30521.1 - 1.2e-32 113.1 24.7 1.2e-24 86.7 6.1 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EPS30521.1 - 4.3e-26 91.4 25.7 4.3e-26 91.4 17.8 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 EPS30521.1 - 1.8e-06 26.6 7.1 1.8e-06 26.6 4.9 2.9 3 0 0 3 3 3 2 MFS/sugar transport protein DUF4516 PF14990.1 EPS30521.1 - 0.041 13.4 0.1 0.11 12.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4516) ZYG-11_interact PF05884.7 EPS30521.1 - 0.11 11.6 4.3 0.24 10.4 0.1 2.8 3 0 0 3 3 3 0 Interactor of ZYG-11 DUF4231 PF14015.1 EPS30521.1 - 4.7 7.2 6.4 45 4.0 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF4231) Aminotran_5 PF00266.14 EPS30524.1 - 2.8e-32 111.8 0.0 4.1e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.11 EPS30524.1 - 5e-28 97.2 0.0 1.2e-27 95.9 0.0 1.7 2 0 0 2 2 2 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EPS30524.1 - 2.9e-18 65.6 0.0 5.4e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 MOSC domain TPR_16 PF13432.1 EPS30526.1 - 1.9e-06 28.3 6.1 0.0016 19.0 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat Suf PF05843.9 EPS30526.1 - 1.9e-06 27.8 4.0 0.0028 17.4 0.1 3.2 3 0 0 3 3 3 2 Suppressor of forked protein (Suf) TPR_19 PF14559.1 EPS30526.1 - 8.5e-05 22.8 0.0 0.12 12.7 0.0 3.9 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EPS30526.1 - 0.0002 21.7 9.1 3.8 8.4 0.0 7.5 8 2 2 10 10 10 1 Tetratricopeptide repeat FAT PF02259.18 EPS30526.1 - 0.0028 16.7 3.3 0.005 15.8 0.1 2.8 3 1 1 4 4 4 1 FAT domain TPR_12 PF13424.1 EPS30526.1 - 0.0051 16.7 0.0 2.6 8.0 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat HAT PF02184.11 EPS30526.1 - 0.17 11.6 16.1 11 5.8 0.0 6.1 6 0 0 6 6 6 0 HAT (Half-A-TPR) repeat NRDE-2 PF08424.5 EPS30526.1 - 0.29 9.9 11.8 0.099 11.5 0.8 4.2 4 2 1 5 5 5 0 NRDE-2, necessary for RNA interference TPR_6 PF13174.1 EPS30526.1 - 2.8 8.6 6.6 13 6.4 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat DEAD PF00270.24 EPS30527.1 - 9.7e-41 139.0 0.0 8e-40 136.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPS30527.1 - 2.5e-26 91.3 0.2 6e-26 90.1 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2986 PF11661.3 EPS30527.1 - 0.0013 19.0 5.6 0.0057 16.9 3.9 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2986) DUF3334 PF11813.3 EPS30527.1 - 0.038 13.5 0.0 0.088 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) Peptidase_M1 PF01433.15 EPS30528.1 - 1.3e-145 485.4 0.4 2e-145 484.7 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EPS30528.1 - 7.7e-94 314.5 0.0 1.7e-93 313.4 0.0 1.6 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EPS30528.1 - 3e-19 69.3 0.2 5.9e-19 68.3 0.1 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily DUF2808 PF10989.3 EPS30528.1 - 0.022 14.3 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) AA_permease_2 PF13520.1 EPS30529.1 - 9.1e-96 320.9 33.6 1.1e-95 320.6 23.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPS30529.1 - 2.4e-22 78.9 31.4 3.5e-22 78.4 21.8 1.3 1 0 0 1 1 1 1 Amino acid permease DUF3543 PF12063.3 EPS30530.1 - 1.9e-98 328.4 0.0 3e-98 327.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 EPS30530.1 - 2e-63 213.9 0.0 3.4e-63 213.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS30530.1 - 6.8e-42 143.3 0.0 1.2e-41 142.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase SAE2 PF08573.5 EPS30531.1 - 0.18 12.5 1.6 0.23 12.1 1.1 1.2 1 0 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus CTP_transf_1 PF01148.15 EPS30532.1 - 6.2e-08 32.6 10.5 0.0015 18.2 0.4 2.9 2 0 0 2 2 2 2 Cytidylyltransferase family ATP_bind_4 PF01902.12 EPS30533.1 - 4.2e-18 65.5 0.0 1.5e-10 40.7 0.0 3.9 2 1 0 3 3 3 3 ATP-binding region Ribonuc_L-PSP PF01042.16 EPS30533.1 - 4.3e-17 61.9 0.0 3.2e-08 33.3 0.0 3.4 3 0 0 3 3 3 2 Endoribonuclease L-PSP Cwf_Cwc_15 PF04889.7 EPS30533.1 - 2.6 7.6 4.8 0.37 10.4 0.1 1.9 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein zf-C2H2 PF00096.21 EPS30534.1 - 4.3e-12 45.6 12.1 2.4e-06 27.5 0.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPS30534.1 - 5.1e-10 38.9 10.7 0.00027 21.0 3.7 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EPS30534.1 - 3.8e-07 30.0 11.9 2.9e-06 27.2 3.0 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EPS30534.1 - 1.4e-05 25.1 5.5 0.0024 17.9 0.6 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EPS30534.1 - 9.8e-05 22.4 4.9 0.0033 17.5 0.3 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EPS30534.1 - 0.018 14.9 9.4 0.022 14.6 0.2 2.8 2 1 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.10 EPS30534.1 - 4.8 7.0 7.6 3.5 7.4 2.6 2.2 1 1 1 2 2 2 0 BED zinc finger PITH PF06201.8 EPS30540.1 - 3.2e-39 134.1 0.0 5.1e-39 133.4 0.0 1.3 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 EPS30540.1 - 9.3e-27 92.7 0.0 1.8e-26 91.8 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EPS30540.1 - 2.4e-06 27.5 0.0 0.00072 19.6 0.0 2.5 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EPS30540.1 - 6.6e-06 26.2 0.0 2.9e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 EPS30540.1 - 2.4e-05 23.9 0.0 4.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 EPS30540.1 - 0.013 15.1 0.1 0.62 9.7 0.0 2.3 1 1 1 2 2 2 0 AhpC/TSA family Thioredoxin_7 PF13899.1 EPS30540.1 - 0.036 14.0 0.0 0.081 12.9 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like Redoxin PF08534.5 EPS30540.1 - 0.1 12.1 0.2 1.9 8.0 0.0 2.2 1 1 1 2 2 2 0 Redoxin zf-CSL PF05207.8 EPS30541.1 - 1.2e-18 66.3 3.4 1.8e-18 65.7 2.3 1.3 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 EPS30541.1 - 1.9e-13 49.8 1.1 7.4e-13 48.0 0.8 1.9 1 1 0 1 1 1 1 DnaJ domain peroxidase PF00141.18 EPS30542.1 - 4.2e-52 176.9 0.0 6.4e-52 176.3 0.0 1.2 1 0 0 1 1 1 1 Peroxidase ArfGap PF01412.13 EPS30545.1 - 6.6e-37 125.8 0.1 6.6e-37 125.8 0.1 1.8 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf UBA PF00627.26 EPS30545.1 - 0.077 12.8 0.2 0.16 11.8 0.2 1.6 1 0 0 1 1 1 0 UBA/TS-N domain Glyco_transf_22 PF03901.12 EPS30546.1 - 7.6e-80 268.9 16.3 9.6e-80 268.6 11.3 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Aminotran_3 PF00202.16 EPS30547.1 - 9.2e-107 356.7 0.0 1.1e-106 356.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EPS30547.1 - 0.072 12.0 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EPS30547.1 - 0.077 12.1 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 Beta-eliminating lyase ABC_membrane PF00664.18 EPS30548.1 - 7.3e-49 166.6 38.6 6.1e-27 94.7 14.4 3.2 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 EPS30548.1 - 2.3e-47 160.7 0.0 1.1e-25 90.4 0.0 2.9 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EPS30548.1 - 5.4e-07 29.8 2.0 0.17 11.8 0.1 4.5 3 2 0 5 5 5 2 AAA domain MMR_HSR1 PF01926.18 EPS30548.1 - 1.2e-06 28.4 0.1 0.058 13.3 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 EPS30548.1 - 2.7e-06 27.8 0.3 0.071 13.6 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein SMC_N PF02463.14 EPS30548.1 - 4.4e-06 26.0 1.5 0.26 10.5 0.1 3.6 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.7 EPS30548.1 - 7.5e-06 25.1 0.0 0.052 12.6 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_17 PF13207.1 EPS30548.1 - 6.8e-05 23.6 0.1 0.6 10.9 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 EPS30548.1 - 9.4e-05 21.8 0.7 0.15 11.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EPS30548.1 - 0.00038 19.6 1.8 0.081 12.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EPS30548.1 - 0.00088 19.3 4.5 0.29 11.0 0.0 3.1 3 1 0 3 3 2 2 AAA ATPase domain Dynamin_N PF00350.18 EPS30548.1 - 0.0015 18.3 0.9 0.27 11.0 0.0 2.8 2 0 0 2 2 2 1 Dynamin family ArgK PF03308.11 EPS30548.1 - 0.0025 16.6 1.9 1.1 7.9 0.0 2.4 2 0 0 2 2 2 2 ArgK protein AAA_22 PF13401.1 EPS30548.1 - 0.012 15.8 1.9 10 6.2 0.0 4.2 4 0 0 4 4 4 0 AAA domain AAA_18 PF13238.1 EPS30548.1 - 0.017 15.3 1.8 17 5.6 0.2 3.4 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 EPS30548.1 - 0.019 14.3 0.1 4 6.7 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EPS30548.1 - 0.026 13.9 0.2 6.7 6.0 0.1 2.7 2 0 0 2 2 2 0 AAA-like domain DUF87 PF01935.12 EPS30548.1 - 0.026 14.3 1.7 0.23 11.2 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_23 PF13476.1 EPS30548.1 - 0.054 13.8 6.8 0.51 10.6 0.1 3.4 4 0 0 4 4 4 0 AAA domain AAA_15 PF13175.1 EPS30548.1 - 0.063 12.3 0.1 6.9 5.5 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_28 PF13521.1 EPS30548.1 - 0.11 12.3 0.7 0.92 9.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain FMN_red PF03358.10 EPS30549.1 - 1.3e-29 102.6 0.0 2.2e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EPS30549.1 - 6.8e-09 35.5 0.0 1e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Exo_endo_phos PF03372.18 EPS30550.1 - 2.2e-08 34.3 1.7 3.3e-08 33.7 1.2 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Jacalin PF01419.12 EPS30550.1 - 0.0029 17.4 0.2 0.0071 16.2 0.1 1.7 1 1 0 1 1 1 1 Jacalin-like lectin domain DUF2244 PF10003.4 EPS30551.1 - 0.19 11.1 0.1 0.19 11.1 0.1 2.6 2 1 0 2 2 2 0 Integral membrane protein (DUF2244) DUF3413 PF11893.3 EPS30551.1 - 0.22 10.3 5.6 0.07 11.9 1.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3413) HemY_N PF07219.8 EPS30551.1 - 1.2 8.7 5.7 4.4 6.8 0.5 2.4 2 0 0 2 2 2 0 HemY protein N-terminus PLDc_N PF13396.1 EPS30551.1 - 2.3 7.9 12.4 0.22 11.2 0.5 3.3 3 0 0 3 3 3 0 Phospholipase_D-nuclease N-terminal PAP2 PF01569.16 EPS30554.1 - 5.6e-27 93.9 1.4 1.5e-26 92.5 0.2 2.1 2 0 0 2 2 2 1 PAP2 superfamily RebB PF11747.3 EPS30554.1 - 0.53 10.2 3.6 1.1 9.1 2.5 1.4 1 0 0 1 1 1 0 Killing trait NGP1NT PF08153.7 EPS30557.1 - 1.2e-48 164.3 0.1 1.8e-48 163.7 0.1 1.3 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 EPS30557.1 - 3.5e-19 68.8 0.0 1e-14 54.4 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EPS30557.1 - 1.2e-05 24.6 0.1 6.8e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EPS30557.1 - 3.7e-05 23.6 0.2 0.29 10.9 0.0 3.5 2 1 1 3 3 3 1 Dynamin family Arf PF00025.16 EPS30557.1 - 0.00051 19.3 0.1 0.13 11.5 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.22 EPS30557.1 - 0.0016 17.9 0.0 0.34 10.3 0.0 3.0 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EPS30557.1 - 0.0045 16.1 0.0 0.0092 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Pkinase PF00069.20 EPS30558.1 - 3.3e-41 141.1 0.0 1.5e-40 138.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS30558.1 - 5.9e-30 104.1 0.0 8.9e-30 103.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPS30558.1 - 0.00098 18.1 0.0 0.0044 16.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EPS30558.1 - 0.008 15.2 0.0 0.017 14.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPS30558.1 - 0.068 12.8 1.5 0.22 11.2 0.1 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family DUF3375 PF11855.3 EPS30558.1 - 0.13 10.9 0.4 0.24 10.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) Pox_ser-thr_kin PF05445.6 EPS30558.1 - 0.14 10.9 0.1 0.49 9.1 0.0 1.7 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Prefoldin_3 PF13758.1 EPS30559.1 - 2e-34 117.2 2.5 5.8e-34 115.8 1.7 1.8 1 0 0 1 1 1 1 Prefoldin subunit DUF3835 PF12927.2 EPS30559.1 - 4e-21 75.7 0.3 4e-21 75.7 0.2 5.7 5 2 0 5 5 5 2 Domain of unknown function (DUF3835) TMF_TATA_bd PF12325.3 EPS30559.1 - 1 9.1 7.1 3.5 7.3 0.1 3.8 3 1 2 5 5 5 0 TATA element modulatory factor 1 TATA binding DUF947 PF06102.7 EPS30559.1 - 7.9 6.2 9.1 2.2 8.1 1.7 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF947) MAT1 PF06391.8 EPS30560.1 - 3.7e-37 127.8 17.4 4.9e-37 127.4 12.0 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 EPS30560.1 - 9.5e-05 21.9 3.4 0.00026 20.5 2.4 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPS30560.1 - 0.00022 20.8 5.8 0.00056 19.5 4.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPS30560.1 - 0.00061 19.7 5.4 0.0014 18.6 3.8 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPS30560.1 - 0.0018 18.0 5.9 0.0038 17.0 4.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EPS30560.1 - 0.0046 16.6 8.1 0.041 13.6 5.9 2.2 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.1 EPS30560.1 - 0.0081 15.7 6.4 0.046 13.3 1.3 2.4 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain DUF572 PF04502.8 EPS30560.1 - 0.014 14.6 10.2 0.018 14.2 7.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) APG6 PF04111.7 EPS30560.1 - 2.7 6.9 13.0 3.9 6.4 9.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Cep57_MT_bd PF06657.8 EPS30561.1 - 2.2e-29 101.2 1.2 2.2e-29 101.2 0.9 4.5 4 0 0 4 4 4 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.1 EPS30561.1 - 7.3e-21 73.8 12.4 7.3e-21 73.8 8.6 4.5 5 0 0 5 5 5 2 Centrosome localisation domain of PPC89 HALZ PF02183.13 EPS30561.1 - 1.3 8.8 14.2 0.024 14.3 2.1 3.1 3 0 0 3 3 3 0 Homeobox associated leucine zipper NYD-SP28_assoc PF14775.1 EPS30561.1 - 3 7.5 10.1 7.9 6.2 1.8 3.0 2 0 0 2 2 2 0 Sperm tail C-terminal domain DUF3682 PF12446.3 EPS30563.1 - 0.017 15.4 3.8 0.017 15.4 2.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) CW_binding_2 PF04122.7 EPS30563.1 - 0.058 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Putative cell wall binding repeat 2 Abhydrolase_6 PF12697.2 EPS30564.1 - 4.1e-14 53.0 0.8 4.8e-14 52.7 0.6 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPS30564.1 - 2.1e-06 27.5 0.0 2.6e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family ABC_membrane PF00664.18 EPS30565.1 - 6.8e-67 225.7 29.0 6e-36 124.2 7.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EPS30565.1 - 5.6e-56 188.6 0.0 1.3e-26 93.5 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EPS30565.1 - 9.7e-17 60.9 1.1 1.3e-06 27.7 0.0 4.5 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EPS30565.1 - 1.1e-15 58.4 0.1 0.0006 19.8 0.0 4.2 3 1 0 3 3 3 3 AAA domain AAA_29 PF13555.1 EPS30565.1 - 2e-08 33.6 1.4 0.003 17.0 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EPS30565.1 - 4.7e-08 33.8 0.1 0.019 15.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EPS30565.1 - 8.1e-07 29.2 0.3 0.063 13.4 0.1 3.6 3 1 0 3 3 2 2 AAA domain AAA_18 PF13238.1 EPS30565.1 - 9.9e-07 29.1 0.1 0.019 15.2 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EPS30565.1 - 2.3e-06 27.7 0.9 0.076 12.9 0.4 3.4 2 1 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 EPS30565.1 - 1.1e-05 24.9 0.0 0.23 10.8 0.0 3.3 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 EPS30565.1 - 1.5e-05 24.2 0.1 0.09 11.9 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 EPS30565.1 - 4.7e-05 23.8 0.3 0.011 16.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.4 EPS30565.1 - 0.00019 20.1 0.1 0.1 11.1 0.1 3.6 3 1 0 3 3 3 1 Predicted ATPase of the ABC class FtsK_SpoIIIE PF01580.13 EPS30565.1 - 0.00023 20.6 0.0 0.16 11.4 0.0 2.7 3 0 0 3 3 2 1 FtsK/SpoIIIE family AAA_10 PF12846.2 EPS30565.1 - 0.00078 18.9 2.3 0.78 9.1 0.2 3.1 4 0 0 4 4 4 2 AAA-like domain SbcCD_C PF13558.1 EPS30565.1 - 0.00091 19.0 0.1 2.1 8.2 0.0 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MobB PF03205.9 EPS30565.1 - 0.001 18.8 0.2 0.99 9.1 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_15 PF13175.1 EPS30565.1 - 0.0018 17.4 0.0 1.2 8.1 0.0 3.2 4 0 0 4 4 4 1 AAA ATPase domain AAA_19 PF13245.1 EPS30565.1 - 0.0019 17.9 0.1 0.24 11.1 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_13 PF13166.1 EPS30565.1 - 0.0043 15.5 0.2 12 4.2 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.1 EPS30565.1 - 0.0059 16.4 0.5 3.1 7.6 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EPS30565.1 - 0.0061 16.2 0.0 4.7 6.9 0.0 2.8 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 EPS30565.1 - 0.0079 15.8 0.1 1.1 8.9 0.1 2.6 2 0 0 2 2 2 1 NACHT domain IstB_IS21 PF01695.12 EPS30565.1 - 0.0081 15.5 0.1 3.1 7.1 0.0 3.7 4 0 0 4 4 4 1 IstB-like ATP binding protein DUF3987 PF13148.1 EPS30565.1 - 0.01 14.4 0.1 2.1 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AAA_30 PF13604.1 EPS30565.1 - 0.012 15.1 0.1 0.88 9.1 0.0 3.3 2 1 1 3 3 3 0 AAA domain DUF87 PF01935.12 EPS30565.1 - 0.023 14.4 2.6 0.23 11.2 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 T2SE PF00437.15 EPS30565.1 - 0.034 13.0 0.0 6.1 5.6 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Gtr1_RagA PF04670.7 EPS30565.1 - 0.041 13.0 0.0 3.5 6.6 0.0 2.7 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Sigma54_activat PF00158.21 EPS30565.1 - 0.058 12.8 0.0 3.6 7.0 0.0 2.6 3 0 0 3 3 2 0 Sigma-54 interaction domain RNA_helicase PF00910.17 EPS30565.1 - 0.083 13.0 0.0 26 5.0 0.0 2.9 2 0 0 2 2 2 0 RNA helicase Synapsin_N PF10581.4 EPS30565.1 - 0.14 11.9 1.3 0.21 11.4 0.1 1.9 2 0 0 2 2 1 0 Synapsin N-terminal APS_kinase PF01583.15 EPS30565.1 - 0.15 11.7 0.1 16 5.0 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase MMR_HSR1 PF01926.18 EPS30565.1 - 0.18 11.7 0.1 3.2 7.7 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase CbiA PF01656.18 EPS30565.1 - 0.22 10.9 1.9 14 5.0 0.2 2.4 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain PhoH PF02562.11 EPS30565.1 - 0.24 10.6 1.5 20 4.3 0.1 3.1 3 0 0 3 3 3 0 PhoH-like protein NB-ARC PF00931.17 EPS30565.1 - 0.38 9.5 1.4 4.1 6.1 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain PduV-EutP PF10662.4 EPS30565.1 - 0.39 10.2 1.9 0.93 8.9 0.2 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 EPS30565.1 - 0.52 9.8 1.5 11 5.4 0.3 2.5 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EPS30565.1 - 0.89 8.6 7.5 1.3 8.1 0.2 3.4 4 0 0 4 4 4 0 KaiC Polysacc_synt_4 PF04669.8 EPS30566.1 - 3.9e-23 81.8 2.4 2.1e-22 79.3 1.7 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis Ric8 PF10165.4 EPS30567.1 - 6.9e-129 430.5 0.0 8.1e-129 430.3 0.0 1.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Rif1_N PF12231.3 EPS30568.1 - 8.7e-139 462.6 2.1 1.2e-138 462.0 1.5 1.2 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Aldo_ket_red PF00248.16 EPS30569.1 - 8.6e-49 165.8 0.0 1e-48 165.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family PUA PF01472.15 EPS30569.1 - 0.02 14.5 0.1 0.043 13.5 0.1 1.6 1 0 0 1 1 1 0 PUA domain Aldose_epim PF01263.15 EPS30570.1 - 1.2e-39 136.2 0.1 1.5e-39 135.9 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase CARDB PF07705.6 EPS30570.1 - 0.019 14.9 0.7 0.047 13.7 0.5 1.6 1 0 0 1 1 1 0 CARDB DUF4432 PF14486.1 EPS30570.1 - 0.092 11.2 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) Ski_Sno PF02437.12 EPS30570.1 - 0.1 12.1 0.0 0.26 10.8 0.0 1.6 2 0 0 2 2 2 0 SKI/SNO/DAC family AA_permease_2 PF13520.1 EPS30571.1 - 7.7e-48 163.0 45.7 9.5e-48 162.7 31.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPS30571.1 - 2e-20 72.5 39.7 2.8e-20 72.1 27.5 1.1 1 0 0 1 1 1 1 Amino acid permease Bac_thur_toxin PF01338.13 EPS30572.1 - 0.076 12.2 0.1 0.13 11.5 0.1 1.3 1 0 0 1 1 1 0 Bacillus thuringiensis toxin Glyco_hydro_15 PF00723.16 EPS30575.1 - 2.4e-97 326.3 0.0 2.8e-97 326.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 EPS30575.1 - 5.5e-26 90.0 0.0 1.2e-25 88.8 0.0 1.6 1 0 0 1 1 1 1 Starch binding domain UBA_4 PF14555.1 EPS30576.1 - 0.0084 15.6 0.0 0.021 14.3 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain DAHP_synth_2 PF01474.11 EPS30577.1 - 2.7e-195 648.8 0.0 3.1e-195 648.6 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family adh_short PF00106.20 EPS30579.1 - 6e-15 55.5 0.7 1.7e-14 54.1 0.5 1.7 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EPS30579.1 - 3e-06 26.8 0.0 8.7e-06 25.3 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EPS30579.1 - 0.0012 18.5 0.2 0.0021 17.7 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EPS30579.1 - 0.0015 18.5 0.1 0.0034 17.3 0.1 1.6 2 0 0 2 2 2 1 NADH(P)-binding adh_short_C2 PF13561.1 EPS30579.1 - 0.0035 17.1 0.0 0.005 16.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short_C2 PF13561.1 EPS30580.1 - 5.3e-30 104.9 0.0 6.2e-30 104.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EPS30580.1 - 1.7e-28 99.6 2.1 2.2e-28 99.2 1.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPS30580.1 - 8.8e-16 58.0 0.7 1.2e-15 57.6 0.5 1.1 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.14 EPS30580.1 - 0.015 14.4 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EPS30580.1 - 0.039 14.1 0.0 0.07 13.3 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding PTR2 PF00854.16 EPS30582.1 - 5.2e-42 143.9 12.5 3.4e-41 141.2 8.7 2.0 1 1 0 1 1 1 1 POT family MFS_1 PF07690.11 EPS30582.1 - 1e-07 31.0 21.3 4.7e-07 28.8 14.1 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily PASTA PF03793.14 EPS30582.1 - 0.12 11.9 0.1 6.6 6.4 0.0 2.8 3 0 0 3 3 3 0 PASTA domain RVT_2 PF07727.9 EPS30584.1 - 1.9e-09 36.8 0.0 2.4e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PLA2_B PF01735.13 EPS30585.1 - 9.9e-201 667.1 2.3 1.2e-200 666.9 1.6 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain mRNA_triPase PF02940.10 EPS30586.1 - 4.9e-59 199.6 0.2 6.8e-59 199.2 0.2 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Acyl_transf_3 PF01757.17 EPS30587.1 - 6.8e-33 113.9 40.9 1.4e-32 112.8 28.3 1.5 1 1 0 1 1 1 1 Acyltransferase family MMgT PF10270.4 EPS30587.1 - 0.24 11.8 2.3 0.41 11.1 0.0 2.4 3 0 0 3 3 3 0 Membrane magnesium transporter WD40 PF00400.27 EPS30588.1 - 1.5e-22 78.5 17.8 7e-09 35.2 0.0 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat CTP_transf_2 PF01467.21 EPS30589.1 - 2.4e-05 24.4 0.2 0.00012 22.1 0.2 2.1 1 1 0 1 1 1 1 Cytidylyltransferase FAD_syn PF06574.7 EPS30589.1 - 0.15 11.6 0.1 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 FAD synthetase F-box-like PF12937.2 EPS30591.1 - 0.0025 17.5 0.0 0.013 15.2 0.0 2.3 1 1 0 1 1 1 1 F-box-like His_Phos_2 PF00328.17 EPS30592.1 - 1.5e-66 225.1 0.0 1.8e-66 224.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) APG6 PF04111.7 EPS30593.1 - 0.091 11.7 3.7 0.13 11.2 2.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 bZIP_2 PF07716.10 EPS30593.1 - 0.8 9.5 14.5 1.6 8.6 9.7 1.7 1 1 0 1 1 1 0 Basic region leucine zipper IncA PF04156.9 EPS30593.1 - 4.2 6.9 7.3 7.7 6.0 5.0 1.4 1 0 0 1 1 1 0 IncA protein SGL PF08450.7 EPS30595.1 - 1.3e-77 260.5 0.0 1.5e-77 260.3 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Aldedh PF00171.17 EPS30596.1 - 4.5e-188 625.2 0.4 5.1e-188 625.1 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EPS30596.1 - 0.00063 18.5 0.0 0.0011 17.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 EPS30596.1 - 0.0007 18.8 0.0 0.0015 17.8 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) EVE PF01878.13 EPS30597.1 - 1.3e-52 177.6 0.1 2.1e-52 176.9 0.1 1.3 1 0 0 1 1 1 1 EVE domain AT_hook PF02178.14 EPS30597.1 - 7.3e-09 34.2 66.9 0.049 13.3 3.6 7.1 6 0 0 6 6 6 6 AT hook motif AhpC-TSA PF00578.16 EPS30598.1 - 2.1e-33 114.6 0.0 3.4e-33 113.9 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 EPS30598.1 - 4.9e-14 51.6 0.5 7.6e-14 51.0 0.3 1.3 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 EPS30598.1 - 1.3e-13 50.7 0.0 1.8e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Redoxin Kelch_4 PF13418.1 EPS30599.1 - 3.2e-20 71.6 0.6 3.5e-09 36.3 0.0 5.3 4 1 0 4 4 4 3 Galactose oxidase, central domain Kelch_3 PF13415.1 EPS30599.1 - 2.7e-19 68.7 4.8 1.2e-10 41.2 0.0 5.6 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.1 EPS30599.1 - 3.9e-11 42.6 7.9 3.4e-05 23.6 0.0 4.5 4 1 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 EPS30599.1 - 7.5e-10 38.1 0.1 0.0042 16.8 0.0 4.5 3 1 0 3 3 3 3 Kelch motif Kelch_1 PF01344.20 EPS30599.1 - 3.1e-09 36.2 0.0 0.15 11.6 0.0 3.7 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.1 EPS30599.1 - 5.3e-08 32.6 4.7 0.17 12.0 0.0 5.1 4 1 0 4 4 4 2 Kelch motif BTB PF00651.26 EPS30599.1 - 0.012 15.5 0.0 1.7 8.6 0.0 2.3 2 0 0 2 2 2 0 BTB/POZ domain Ribophorin_II PF05817.9 EPS30602.1 - 3.8e-20 71.6 0.2 4.7e-20 71.3 0.1 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II ERp29 PF07749.7 EPS30603.1 - 0.085 13.5 0.1 0.12 12.9 0.1 1.2 1 0 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain ADH_N PF08240.7 EPS30604.1 - 1.2e-19 70.0 6.1 2.4e-19 69.1 4.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPS30604.1 - 1.9e-13 50.0 0.0 3e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EPS30604.1 - 0.0001 21.5 0.1 0.00018 20.7 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EPS30604.1 - 0.0067 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EPS30604.1 - 0.044 13.4 0.1 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 EPS30604.1 - 0.18 11.5 1.4 0.33 10.7 1.0 1.3 1 0 0 1 1 1 0 ThiF family Orai-1 PF07856.7 EPS30605.1 - 0.12 11.8 0.0 0.15 11.6 0.0 1.0 1 0 0 1 1 1 0 Mediator of CRAC channel activity Sulfatase PF00884.18 EPS30606.1 - 2.7e-19 69.5 0.6 4.2e-19 68.8 0.4 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EPS30606.1 - 2e-08 33.9 0.1 4.3e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EPS30606.1 - 0.00012 20.6 0.1 0.00017 20.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF1048 PF06304.6 EPS30606.1 - 0.13 12.6 0.0 1.5 9.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1048) Fungal_trans_2 PF11951.3 EPS30607.1 - 1.5e-07 30.3 3.0 1.4e-05 23.9 0.2 2.3 1 1 1 2 2 2 2 Fungal specific transcription factor domain DUF2285 PF10074.4 EPS30607.1 - 0.084 13.2 0.0 0.23 11.8 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2285) MFS_1 PF07690.11 EPS30609.1 - 1.2e-26 93.2 24.5 1.2e-26 93.2 17.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS30609.1 - 5.4e-14 51.6 6.9 5.4e-14 51.6 4.8 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter DUF3237 PF11578.3 EPS30610.1 - 2.2e-29 101.7 0.0 2.5e-29 101.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Amidase PF01425.16 EPS30611.1 - 2.4e-95 320.0 0.0 2.8e-95 319.7 0.0 1.0 1 0 0 1 1 1 1 Amidase NAD_binding_4 PF07993.7 EPS30612.1 - 2e-38 131.7 0.0 3e-38 131.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EPS30612.1 - 2.7e-34 118.2 0.0 5.9e-34 117.1 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EPS30612.1 - 1.1e-15 57.7 0.0 2.1e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPS30612.1 - 0.00014 20.6 0.0 0.00025 19.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EPS30612.1 - 0.00068 19.6 0.1 0.01 15.8 0.1 2.3 1 1 0 1 1 1 1 NADH(P)-binding PP-binding PF00550.20 EPS30612.1 - 0.0081 16.4 0.2 0.021 15.0 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 EPS30612.1 - 0.0081 16.0 0.5 0.021 14.7 0.3 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPS30612.1 - 0.012 15.2 0.3 0.037 13.6 0.2 1.9 1 1 0 1 1 1 0 KR domain NmrA PF05368.8 EPS30612.1 - 0.02 14.1 0.0 0.043 13.0 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.12 EPS30612.1 - 0.024 13.5 0.6 0.52 9.1 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain DapB_N PF01113.15 EPS30612.1 - 0.034 14.0 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 EPS30612.1 - 0.12 12.6 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain CTD PF12815.2 EPS30613.1 - 2.4e-32 111.9 47.4 3.1e-28 98.6 18.7 3.7 1 1 2 3 3 3 3 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5-NGN PF03439.8 EPS30613.1 - 4.1e-19 68.1 0.0 6.8e-19 67.4 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 EPS30613.1 - 2.1e-17 63.5 11.3 2.1e-17 63.5 7.8 3.5 2 1 1 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 EPS30613.1 - 5.6e-12 44.8 5.7 0.0003 20.3 0.0 4.6 5 0 0 5 5 5 3 KOW motif SDA1 PF05285.7 EPS30613.1 - 2.5 7.2 35.0 4.7 6.3 24.3 1.4 1 0 0 1 1 1 0 SDA1 TFIIF_alpha PF05793.7 EPS30613.1 - 4 5.6 36.5 5.9 5.1 25.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Acyl-CoA_dh_1 PF00441.19 EPS30614.1 - 4.5e-40 137.1 0.6 6.5e-40 136.6 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EPS30614.1 - 4.9e-20 70.7 0.1 9.6e-20 69.8 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 EPS30614.1 - 2.8e-19 68.6 0.3 5.7e-19 67.7 0.2 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 EPS30614.1 - 4.2e-17 62.7 0.0 8.8e-17 61.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EPS30614.1 - 7.3e-07 29.5 0.0 1.2e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain PC_rep PF01851.17 EPS30616.1 - 9.6e-41 135.7 20.6 1.4e-09 37.6 0.0 10.2 10 0 0 10 10 10 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EPS30616.1 - 1.8e-17 63.3 6.9 1e-12 48.1 0.0 5.0 4 1 2 6 6 6 3 HEAT repeats HEAT PF02985.17 EPS30616.1 - 2.4e-07 30.2 0.1 3.3 8.0 0.0 5.7 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 EPS30616.1 - 3.8e-06 27.2 10.2 4.1e-06 27.1 0.0 4.9 5 1 1 6 6 6 1 HEAT-like repeat HEAT_PBS PF03130.11 EPS30616.1 - 0.062 13.7 2.0 0.88 10.2 0.0 3.9 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Reo_sigmaC PF04582.7 EPS30617.1 - 0.034 13.3 0.7 0.065 12.3 0.2 1.7 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF465 PF04325.8 EPS30617.1 - 0.25 11.0 6.3 3.5 7.4 0.1 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF465) CENP-H PF05837.7 EPS30617.1 - 0.54 10.4 4.8 0.45 10.7 0.2 2.9 3 0 0 3 3 3 0 Centromere protein H (CENP-H) Seryl_tRNA_N PF02403.17 EPS30617.1 - 1.9 8.5 9.4 1.2 9.1 1.3 2.9 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain APG6 PF04111.7 EPS30617.1 - 6.6 5.6 9.6 4.9 6.1 1.4 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 IncA PF04156.9 EPS30617.1 - 9.9 5.7 16.7 0.021 14.4 2.6 2.6 3 0 0 3 3 3 0 IncA protein Abhydrolase_5 PF12695.2 EPS30618.1 - 5.1e-08 32.7 0.0 1e-07 31.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPS30618.1 - 6.1e-07 29.5 3.6 1.8e-06 28.0 2.5 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EPS30618.1 - 0.062 12.7 0.0 0.095 12.1 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.3 EPS30618.1 - 0.068 13.0 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase DUF3336 PF11815.3 EPS30619.1 - 5.5e-41 139.4 1.2 1.2e-40 138.3 0.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EPS30619.1 - 4.1e-24 85.6 0.2 1.6e-23 83.6 0.0 2.0 2 0 0 2 2 2 1 Patatin-like phospholipase PMI_typeI PF01238.16 EPS30621.1 - 1.9e-69 234.4 0.0 5.3e-68 229.6 0.0 2.0 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 EPS30621.1 - 0.00051 19.4 0.0 0.098 12.1 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_6 PF12852.2 EPS30621.1 - 0.11 12.0 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 Cupin Glyphos_transf PF04464.9 EPS30621.1 - 0.18 10.5 0.0 0.49 9.0 0.0 1.6 2 0 0 2 2 2 0 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase Nucleoplasmin PF03066.10 EPS30625.1 - 2.4 7.6 5.2 3.9 6.9 3.6 1.3 1 0 0 1 1 1 0 Nucleoplasmin SKG6 PF08693.5 EPS30626.1 - 0.045 13.0 4.6 0.15 11.4 3.2 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Med8 PF10232.4 EPS30627.1 - 9.8e-49 165.8 0.3 4.5e-48 163.7 0.2 1.8 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 YPEB PF14620.1 EPS30627.1 - 0.0015 17.6 0.0 0.0018 17.3 0.0 1.2 1 0 0 1 1 1 1 YpeB sporulation RnfC_N PF13375.1 EPS30627.1 - 0.032 13.9 0.0 0.07 12.8 0.0 1.5 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Myc_N PF01056.13 EPS30627.1 - 0.2 10.8 3.6 0.076 12.1 0.8 1.5 2 0 0 2 2 2 0 Myc amino-terminal region Nucleoplasmin PF03066.10 EPS30627.1 - 0.24 10.9 3.6 0.32 10.5 2.5 1.2 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 EPS30627.1 - 0.36 11.1 2.8 0.67 10.3 2.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PQ-loop PF04193.9 EPS30628.1 - 7.9e-20 70.1 8.3 4.2e-11 42.2 0.8 2.9 3 0 0 3 3 3 2 PQ loop repeat DUF4383 PF14325.1 EPS30628.1 - 2.8 7.9 12.2 13 5.7 8.4 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4383) UbiA PF01040.13 EPS30629.1 - 6.3e-31 107.5 18.8 9.8e-31 106.8 13.0 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family tRNA-synt_2 PF00152.15 EPS30630.1 - 4.6e-106 354.3 0.0 6.1e-106 353.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 EPS30630.1 - 0.00033 20.2 0.0 0.0011 18.6 0.0 1.6 1 1 1 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) ABC_tran PF00005.22 EPS30631.1 - 1.1e-46 158.5 0.0 8e-30 103.9 0.0 2.9 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 EPS30631.1 - 1.1e-36 126.7 33.4 3.4e-23 82.4 9.0 3.5 3 1 1 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.14 EPS30631.1 - 3.7e-10 39.4 0.5 0.016 14.4 0.1 4.9 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain T2SE PF00437.15 EPS30631.1 - 2.6e-05 23.2 0.0 0.038 12.8 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.1 EPS30631.1 - 0.00011 21.6 0.0 0.24 10.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EPS30631.1 - 0.0004 19.8 0.6 0.91 9.0 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EPS30631.1 - 0.00069 19.6 3.3 0.096 12.6 0.2 3.0 3 0 0 3 3 3 1 AAA ATPase domain DUF87 PF01935.12 EPS30631.1 - 0.0011 18.8 2.4 0.34 10.6 0.0 3.2 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_22 PF13401.1 EPS30631.1 - 0.0012 18.9 0.1 5.3 7.2 0.0 3.8 3 0 0 3 3 3 1 AAA domain MMR_HSR1 PF01926.18 EPS30631.1 - 0.0027 17.6 0.1 0.32 10.9 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_10 PF12846.2 EPS30631.1 - 0.0029 17.1 0.4 1.7 7.9 0.0 2.8 2 1 0 3 3 3 2 AAA-like domain DUF258 PF03193.11 EPS30631.1 - 0.006 15.7 0.1 1.7 7.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 EPS30631.1 - 0.011 16.1 0.1 4.9 7.6 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein AAA_21 PF13304.1 EPS30631.1 - 0.016 15.1 0.5 12 5.7 0.0 3.7 3 1 1 4 4 4 0 AAA domain DUF2075 PF09848.4 EPS30631.1 - 0.018 14.0 0.6 0.34 9.8 0.0 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 EPS30631.1 - 0.021 14.3 0.2 8.4 5.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.1 EPS30631.1 - 0.023 15.0 6.9 0.083 13.2 0.0 3.6 4 0 0 4 4 4 0 AAA domain Viral_helicase1 PF01443.13 EPS30631.1 - 0.038 13.4 0.0 0.21 11.1 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase SbcCD_C PF13558.1 EPS30631.1 - 0.042 13.7 0.0 4.3 7.3 0.0 3.0 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit CbiA PF01656.18 EPS30631.1 - 0.21 11.0 2.5 0.59 9.5 0.0 2.8 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain LigD_N PF13298.1 EPS30632.1 - 3.8e-26 91.2 0.1 9.9e-26 89.9 0.1 1.7 1 1 0 1 1 1 1 DNA polymerase Ligase (LigD) FAD_binding_4 PF01565.18 EPS30633.1 - 3.4e-28 97.8 2.0 5.2e-28 97.2 1.4 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EPS30633.1 - 2.6e-12 46.4 0.1 7.1e-12 45.0 0.0 1.8 2 0 0 2 2 2 1 Berberine and berberine like Sulf_transp PF04143.9 EPS30634.1 - 2.2e-14 53.1 28.5 3e-08 33.5 2.0 4.2 4 0 0 4 4 4 2 Sulphur transport DUF4341 PF14241.1 EPS30634.1 - 2.3e-08 33.6 0.9 2.3e-08 33.6 0.7 4.0 3 2 1 4 4 4 1 Domain of unknown function (DUF4341) EmrE PF13536.1 EPS30634.1 - 9 6.5 13.6 4 7.6 0.6 4.0 4 1 1 5 5 5 0 Multidrug resistance efflux transporter Peptidase_M28 PF04389.12 EPS30635.1 - 7.2e-34 117.0 0.1 9.9e-34 116.6 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 PDZ_assoc PF10600.4 EPS30637.1 - 0.057 13.7 0.6 0.15 12.4 0.0 1.9 1 1 1 2 2 2 0 PDZ-associated domain of NMDA receptors Sigma70_r4_2 PF08281.7 EPS30637.1 - 0.084 12.3 0.3 0.18 11.3 0.2 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 DUF1645 PF07816.6 EPS30638.1 - 0.0061 17.0 2.0 0.0073 16.7 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1645) API5 PF05918.6 EPS30638.1 - 0.0069 14.9 0.8 0.0084 14.6 0.6 1.1 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) FoP_duplication PF13865.1 EPS30638.1 - 1.7 9.1 6.5 3.4 8.1 4.5 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 MutS_V PF00488.16 EPS30639.1 - 1.3e-79 266.9 0.1 2e-79 266.3 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EPS30639.1 - 2.6e-50 171.0 0.0 4.6e-50 170.2 0.0 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EPS30639.1 - 1.7e-32 111.8 0.0 3.6e-32 110.7 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.13 EPS30639.1 - 2.9e-14 52.9 0.5 5.9e-14 52.0 0.3 1.6 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 EPS30639.1 - 7.9e-12 45.4 0.0 1.9e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 MutS domain II AAA_29 PF13555.1 EPS30639.1 - 0.031 13.8 0.0 0.072 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.1 EPS30639.1 - 0.13 12.2 0.1 0.49 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EPS30639.1 - 0.39 11.0 0.0 0.39 11.0 0.0 2.4 3 0 0 3 3 3 0 AAA domain DEAD PF00270.24 EPS30640.1 - 4.7e-20 71.7 0.0 9.2e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EPS30640.1 - 2e-08 34.2 0.0 1.4e-07 31.5 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EPS30640.1 - 3.6e-07 29.9 0.1 9.6e-07 28.5 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.11 EPS30640.1 - 0.012 14.8 0.0 0.025 13.8 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein tRNA-synt_1b PF00579.20 EPS30641.1 - 8.7e-73 244.9 0.0 1.2e-72 244.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Raffinose_syn PF05691.7 EPS30642.1 - 3.3e-51 173.7 1.8 1.3e-49 168.4 1.3 2.3 1 1 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 DUF1697 PF08002.6 EPS30642.1 - 0.072 13.1 0.1 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1697) Acetyltransf_1 PF00583.19 EPS30643.1 - 6.6e-17 61.3 0.2 9.3e-17 60.8 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EPS30643.1 - 2.4e-06 27.6 0.0 6.9e-05 22.9 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPS30643.1 - 5.9e-06 25.9 0.0 9.8e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EPS30643.1 - 1.4e-05 25.1 0.2 2.1e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EPS30643.1 - 0.0077 16.1 0.0 0.047 13.6 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EPS30643.1 - 0.046 13.6 0.0 0.083 12.7 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PIG-U PF06728.8 EPS30644.1 - 9e-121 403.3 22.1 1e-120 403.1 15.3 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Mannosyl_trans PF05007.8 EPS30644.1 - 6e-05 22.8 1.5 0.00011 21.9 0.7 1.6 1 1 0 1 1 1 1 Mannosyltransferase (PIG-M) Pescadillo_N PF06732.6 EPS30645.1 - 6.2e-115 383.2 0.3 6.2e-115 383.2 0.2 2.0 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 EPS30645.1 - 1.9e-07 31.1 0.0 1.5e-06 28.2 0.0 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain SGT1 PF07093.6 EPS30645.1 - 0.00074 18.0 15.3 0.0012 17.3 10.6 1.3 1 0 0 1 1 1 1 SGT1 protein RRN9 PF10680.4 EPS30646.1 - 9.2e-16 57.3 1.4 2.8e-15 55.7 1.0 1.8 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor zf-C2H2_4 PF13894.1 EPS30646.1 - 0.056 13.7 4.5 0.11 12.9 1.7 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Macoilin PF09726.4 EPS30646.1 - 9.4 4.3 13.2 0.14 10.4 4.3 1.4 2 0 0 2 2 2 0 Transmembrane protein Aldedh PF00171.17 EPS30647.1 - 2.4e-166 553.6 0.8 2.7e-166 553.4 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EPS30647.1 - 0.0011 17.8 0.0 0.0016 17.2 0.0 1.1 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF4149 PF13664.1 EPS30648.1 - 0.024 14.6 18.3 0.43 10.6 4.5 3.6 1 1 1 3 3 3 0 Domain of unknown function (DUF4149) NfeD PF01957.13 EPS30648.1 - 5.6 7.0 11.5 0.15 12.1 0.8 3.0 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding bZIP_1 PF00170.16 EPS30650.1 - 2.3e-08 33.8 4.2 4.2e-08 33.0 2.9 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EPS30650.1 - 3.1e-05 23.6 2.7 5.9e-05 22.8 1.8 1.4 1 0 0 1 1 1 1 Basic region leucine zipper SR-25 PF10500.4 EPS30650.1 - 1.6 8.1 13.9 0.17 11.3 6.6 1.5 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.20 EPS30651.1 - 5.2e-71 238.8 0.0 6.2e-71 238.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS30651.1 - 1e-33 116.5 0.0 1.2e-33 116.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EPS30651.1 - 3.8e-05 22.8 0.1 8.1e-05 21.7 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EPS30651.1 - 6e-05 22.1 0.1 0.00032 19.7 0.0 1.9 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 EPS30651.1 - 0.0038 16.9 0.2 0.0091 15.7 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EPS30651.1 - 0.014 14.7 0.1 0.027 13.8 0.1 1.5 1 1 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 EPS30651.1 - 0.084 12.4 0.1 0.17 11.4 0.1 1.7 1 1 0 1 1 1 0 Choline/ethanolamine kinase MARVEL PF01284.18 EPS30652.1 - 9.3e-13 48.2 15.9 1.2e-12 47.8 11.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain HIG_1_N PF04588.8 EPS30653.1 - 8.7e-26 89.4 0.2 1.2e-25 88.9 0.1 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region MAS20 PF02064.10 EPS30653.1 - 0.072 12.9 0.3 0.12 12.2 0.2 1.5 1 0 0 1 1 1 0 MAS20 protein import receptor DUF1491 PF07372.7 EPS30653.1 - 0.14 12.1 2.3 0.19 11.6 0.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1491) PALP PF00291.20 EPS30654.1 - 1.1e-71 241.6 0.1 1.3e-71 241.3 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 EPS30654.1 - 6e-45 150.7 0.0 3.5e-22 77.8 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Ribosomal_L36 PF00444.13 EPS30655.1 - 6.8e-20 70.7 9.7 9.7e-20 70.2 6.7 1.2 1 0 0 1 1 1 1 Ribosomal protein L36 YmdB PF13277.1 EPS30655.1 - 0.081 11.9 0.0 0.099 11.6 0.0 1.1 1 0 0 1 1 1 0 YmdB-like protein Crust_neurohorm PF01147.12 EPS30655.1 - 0.1 11.8 0.5 0.15 11.3 0.4 1.2 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family GTP_EFTU PF00009.22 EPS30656.1 - 2e-55 187.1 0.3 3.5e-55 186.3 0.2 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EPS30656.1 - 5.1e-33 112.7 0.0 1e-32 111.7 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 EPS30656.1 - 4.8e-30 103.5 0.1 9e-30 102.7 0.1 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EPS30656.1 - 3.7e-23 81.2 0.0 1.2e-22 79.5 0.0 2.0 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EPS30656.1 - 3.3e-13 49.5 0.0 8.9e-13 48.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Mitofilin PF09731.4 EPS30659.1 - 3.9e-157 524.4 24.8 4.9e-157 524.0 17.2 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein DUF2422 PF10337.4 EPS30659.1 - 1.7 7.3 11.0 1.9 7.1 5.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2422) FtsK_SpoIIIE PF01580.13 EPS30659.1 - 5.9 6.2 8.0 17 4.8 5.5 1.8 1 1 0 1 1 1 0 FtsK/SpoIIIE family Ras PF00071.17 EPS30660.1 - 4.8e-59 198.3 0.2 5.6e-59 198.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPS30660.1 - 6.6e-20 71.7 0.1 1.2e-19 70.9 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EPS30660.1 - 1.3e-14 53.8 0.0 1.6e-14 53.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EPS30660.1 - 3.4e-08 32.9 0.0 4.2e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EPS30660.1 - 7.8e-08 31.9 0.0 1.4e-07 31.1 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EPS30660.1 - 6e-06 26.2 0.0 7.8e-06 25.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EPS30660.1 - 0.0066 16.5 0.0 0.49 10.5 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPS30660.1 - 0.0085 16.0 0.3 0.12 12.3 0.2 2.3 1 1 1 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 EPS30660.1 - 0.03 13.5 0.1 0.1 11.8 0.0 1.8 1 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 EPS30660.1 - 0.11 12.4 0.1 0.2 11.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain Syja_N PF02383.13 EPS30661.1 - 2.8e-94 315.4 0.0 3.4e-94 315.1 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Mur_ligase_M PF08245.7 EPS30662.1 - 2.2e-07 31.1 0.9 1.6e-05 25.0 0.6 3.2 1 1 0 1 1 1 1 Mur ligase middle domain DUF2188 PF09954.4 EPS30662.1 - 0.26 11.2 1.3 0.56 10.1 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) NMT PF01233.14 EPS30663.1 - 8.9e-79 262.7 0.0 1.7e-78 261.8 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 EPS30663.1 - 6.8e-77 257.1 0.0 1.2e-76 256.3 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 EPS30663.1 - 4.7e-07 29.7 0.0 1.4e-05 24.9 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EPS30663.1 - 0.00094 19.3 0.1 0.0076 16.4 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF3347 PF11827.3 EPS30663.1 - 0.2 11.6 2.3 0.36 10.8 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) TLD PF07534.11 EPS30664.1 - 1.6e-22 79.9 0.0 2.5e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 TLD PBP1_TM PF14812.1 EPS30665.1 - 6.5 7.1 6.7 19 5.6 0.3 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mito_fiss_reg PF05308.6 EPS30666.1 - 0.14 11.4 7.3 0.16 11.3 5.0 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator 4HBT_3 PF13622.1 EPS30666.1 - 0.18 11.5 1.8 0.19 11.4 1.2 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily CAP_N PF01213.14 EPS30666.1 - 0.22 10.7 8.4 0.27 10.4 5.8 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF2360 PF10152.4 EPS30666.1 - 2.9 8.1 4.8 3.4 7.9 3.3 1.1 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Abhydrolase_5 PF12695.2 EPS30667.1 - 6.9e-12 45.3 0.0 1.7e-11 44.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPS30667.1 - 7.8e-10 39.0 1.2 1.4e-09 38.1 0.8 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EPS30667.1 - 0.0011 18.7 0.1 0.0052 16.6 0.0 2.0 1 1 0 1 1 1 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 EPS30667.1 - 0.0011 18.5 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Na_Pi_cotrans PF02690.10 EPS30667.1 - 0.0023 17.6 0.0 0.0039 16.9 0.0 1.3 1 0 0 1 1 1 1 Na+/Pi-cotransporter Abhydrolase_1 PF00561.15 EPS30667.1 - 0.0081 15.7 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DSBA PF01323.15 EPS30669.1 - 1.5e-18 67.0 0.0 1.7e-18 66.8 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain FliG_N PF14842.1 EPS30669.1 - 0.17 11.9 0.0 0.25 11.4 0.0 1.1 1 0 0 1 1 1 0 FliG N-terminal domain CAML PF14963.1 EPS30670.1 - 0.34 10.2 5.5 0.45 9.8 3.8 1.3 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Pol_alpha_B_N PF08418.5 EPS30670.1 - 0.96 8.9 11.3 1.2 8.5 7.9 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal cobW PF02492.14 EPS30671.1 - 3.6e-38 130.7 0.0 5.3e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EPS30671.1 - 0.0026 17.4 0.0 0.31 10.7 0.0 2.6 3 0 0 3 3 3 1 Cobalamin synthesis protein cobW C-terminal domain AAA_19 PF13245.1 EPS30671.1 - 0.0081 15.8 0.1 0.022 14.4 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain MobB PF03205.9 EPS30671.1 - 0.0098 15.5 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EPS30671.1 - 0.012 15.7 0.0 0.025 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EPS30671.1 - 0.039 13.4 0.0 1 8.9 0.0 2.8 3 0 0 3 3 3 0 P-loop containing region of AAA domain EAL PF00563.15 EPS30671.1 - 0.04 13.4 0.0 0.063 12.7 0.0 1.3 1 0 0 1 1 1 0 EAL domain Viral_helicase1 PF01443.13 EPS30671.1 - 0.055 12.9 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 EPS30671.1 - 0.079 12.9 0.0 0.26 11.2 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 EPS30671.1 - 0.12 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.7 EPS30671.1 - 0.12 11.6 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein Orn_Arg_deC_N PF02784.11 EPS30672.1 - 9.8e-78 260.7 0.0 1.3e-77 260.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EPS30672.1 - 9.1e-31 105.9 0.0 1.9e-30 104.9 0.0 1.5 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Methyltransf_16 PF10294.4 EPS30673.1 - 4.4e-50 169.5 0.0 6.2e-50 169.0 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EPS30673.1 - 2e-05 25.0 0.0 4.7e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPS30673.1 - 5.2e-05 23.0 0.0 8.7e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPS30673.1 - 0.00012 22.0 0.1 0.00023 21.1 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPS30673.1 - 0.0018 17.8 0.0 0.0027 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPS30673.1 - 0.0023 17.3 0.0 0.0036 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EPS30673.1 - 0.025 13.7 0.0 0.037 13.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) LCM PF04072.9 EPS30673.1 - 0.076 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Leucine carboxyl methyltransferase Methyltransf_12 PF08242.7 EPS30673.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Phage_holin_2 PF04550.7 EPS30673.1 - 0.26 11.4 1.2 0.41 10.7 0.1 1.9 2 0 0 2 2 2 0 Phage holin family 2 Zn_clus PF00172.13 EPS30675.1 - 8.2e-06 25.6 10.9 1.4e-05 24.9 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain M16C_assoc PF08367.6 EPS30676.1 - 6.5e-55 185.6 0.1 1.3e-54 184.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 EPS30676.1 - 3.8e-24 85.3 0.0 3.8e-14 52.7 0.0 2.8 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EPS30676.1 - 2.6e-09 36.9 0.0 2.6e-08 33.7 0.0 2.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Taxilin PF09728.4 EPS30677.1 - 1.9e-101 339.2 50.7 1.9e-101 339.2 35.1 1.6 1 1 1 2 2 2 1 Myosin-like coiled-coil protein AAA_13 PF13166.1 EPS30677.1 - 5.7e-05 21.7 35.6 0.0004 18.9 5.4 2.1 2 0 0 2 2 2 2 AAA domain DUF4201 PF13870.1 EPS30677.1 - 8.1e-05 22.1 15.1 8.1e-05 22.1 10.5 3.7 2 2 2 4 4 4 1 Domain of unknown function (DUF4201) Laminin_I PF06008.9 EPS30677.1 - 0.028 13.7 35.7 0.015 14.5 9.4 3.2 2 1 1 3 3 3 0 Laminin Domain I ERM PF00769.14 EPS30677.1 - 0.21 11.0 54.6 0.06 12.8 14.4 3.4 1 1 2 3 3 3 0 Ezrin/radixin/moesin family HlyD PF00529.15 EPS30677.1 - 1.3 8.2 19.6 2.9 7.1 4.2 2.3 2 0 0 2 2 2 0 HlyD family secretion protein Laminin_II PF06009.7 EPS30677.1 - 2.8 7.6 34.0 3 7.6 4.4 3.8 2 2 3 5 5 5 0 Laminin Domain II ISG65-75 PF11727.3 EPS30677.1 - 4.3 6.3 28.9 0.17 10.9 11.8 2.4 2 1 0 2 2 2 0 Invariant surface glycoprotein APG6 PF04111.7 EPS30677.1 - 4.5 6.2 50.2 0.23 10.4 11.2 3.2 2 1 1 3 3 3 0 Autophagy protein Apg6 NMO PF03060.10 EPS30678.1 - 1e-71 241.7 1.9 1.2e-71 241.5 1.3 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EPS30678.1 - 1.5e-06 27.3 0.1 0.0022 16.9 0.1 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EPS30678.1 - 0.0088 14.9 1.8 0.014 14.3 1.3 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ATP_synt_I PF03899.10 EPS30678.1 - 0.13 12.4 0.1 0.23 11.6 0.1 1.4 1 0 0 1 1 1 0 ATP synthase I chain DNA_pol_E_B PF04042.11 EPS30679.1 - 1.9e-46 157.9 0.0 2.6e-46 157.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Abhydrolase_5 PF12695.2 EPS30679.1 - 0.024 14.3 0.1 0.044 13.5 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Acetyltransf_3 PF13302.1 EPS30680.1 - 4.1e-25 88.5 0.0 5.9e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EPS30680.1 - 4.1e-05 23.5 0.1 0.0059 16.4 0.1 2.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPS30680.1 - 0.0015 18.5 0.0 0.017 15.1 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EPS30680.1 - 0.02 14.6 0.1 0.48 10.2 0.0 2.2 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_4 PF13420.1 EPS30680.1 - 0.094 12.6 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_hydro_61 PF03443.9 EPS30681.1 - 1.7e-84 283.0 0.2 2e-84 282.8 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 GSu_C4xC__C2xCH PF09698.5 EPS30681.1 - 4.8 7.4 8.9 0.32 11.2 0.7 2.9 3 0 0 3 3 3 0 Geobacter CxxxxCH...CXXCH motif (GSu_C4xC__C2xCH) Ribosomal_L38e PF01781.13 EPS30683.1 - 2e-32 110.7 1.8 2.4e-32 110.5 1.3 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family CLTH PF10607.4 EPS30683.1 - 0.072 12.7 0.0 0.08 12.6 0.0 1.2 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain Far-17a_AIG1 PF04750.9 EPS30684.1 - 0.033 13.3 0.4 0.046 12.8 0.0 1.4 2 0 0 2 2 2 0 FAR-17a/AIG1-like protein Ish1 PF10281.4 EPS30685.1 - 8.3e-08 32.1 0.2 1.3e-07 31.5 0.2 1.3 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein DUF1470 PF07336.6 EPS30685.1 - 0.012 15.9 3.3 0.012 15.9 1.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1470) SAP PF02037.22 EPS30685.1 - 0.052 13.0 1.0 0.63 9.6 0.7 2.1 1 1 0 1 1 1 0 SAP domain DUF4129 PF13559.1 EPS30685.1 - 0.12 12.3 0.6 0.18 11.7 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) NTF2 PF02136.15 EPS30686.1 - 8.7e-06 26.0 0.1 1.8e-05 25.0 0.1 1.5 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 EPS30686.1 - 6.5e-05 22.7 0.0 0.0013 18.5 0.0 2.0 2 0 0 2 2 2 1 Nuclear pore RNA shuttling protein Mtr2 tRNA-synt_1g PF09334.6 EPS30687.1 - 3e-114 381.7 0.4 1.1e-113 379.8 0.2 1.9 2 1 0 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EPS30687.1 - 8.7e-24 83.4 0.0 1.7e-11 42.8 0.0 3.1 2 1 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EPS30687.1 - 3e-11 42.9 0.0 5.7e-06 25.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 EPS30687.1 - 0.0014 18.3 0.0 0.0031 17.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Hira PF07569.6 EPS30687.1 - 0.17 11.0 0.2 0.29 10.3 0.2 1.3 1 0 0 1 1 1 0 TUP1-like enhancer of split PALP PF00291.20 EPS30688.1 - 2.7e-46 158.2 7.2 6.6e-45 153.6 3.6 2.9 2 1 1 3 3 3 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.21 EPS30688.1 - 0.36 10.3 6.2 9.6 5.7 0.1 2.9 3 0 0 3 3 3 0 Zinc-binding dehydrogenase PPTA PF01239.17 EPS30689.1 - 5.9e-35 117.1 20.8 6.3e-08 31.6 0.3 5.6 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat DUF924 PF06041.6 EPS30690.1 - 1e-49 168.8 0.1 1.6e-49 168.2 0.1 1.3 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) NVEALA PF14055.1 EPS30690.1 - 0.14 11.9 0.3 0.26 11.0 0.2 1.4 1 0 0 1 1 1 0 NVEALA protein Fungal_trans_2 PF11951.3 EPS30691.1 - 1.6e-25 89.5 1.9 2e-17 62.8 0.3 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS30691.1 - 2.1e-08 33.9 7.8 3.7e-08 33.1 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CP_ATPgrasp_1 PF04174.8 EPS30691.1 - 0.17 10.5 0.0 0.3 9.6 0.0 1.3 1 0 0 1 1 1 0 A circularly permuted ATPgrasp GHMP_kinases_N PF00288.21 EPS30692.1 - 7.2e-19 67.6 0.0 1.6e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EPS30692.1 - 2.1e-05 24.6 0.0 8.6e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 EPS30692.1 - 0.0016 17.6 0.1 0.0035 16.5 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature AA_permease PF00324.16 EPS30693.1 - 6e-61 206.2 31.4 7.4e-61 205.9 21.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPS30693.1 - 4e-17 61.8 38.4 6.2e-17 61.2 26.6 1.3 1 0 0 1 1 1 1 Amino acid permease Nop14 PF04147.7 EPS30693.1 - 3 5.6 3.8 4.6 5.0 2.6 1.2 1 0 0 1 1 1 0 Nop14-like family Aa_trans PF01490.13 EPS30694.1 - 2.7e-80 269.8 28.6 3.3e-80 269.5 19.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MPC PF03650.8 EPS30695.1 - 1.8e-34 118.2 0.1 2e-34 118.0 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) LSM PF01423.17 EPS30696.1 - 1.8e-18 65.8 0.0 2.2e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain Ribosomal_L5_C PF00673.16 EPS30697.1 - 1.7e-22 78.9 0.0 2.5e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EPS30697.1 - 2.2e-21 75.4 0.1 7.3e-21 73.7 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L5 CPSase_L_D2 PF02786.12 EPS30699.1 - 1.4e-80 269.5 0.2 2.3e-80 268.8 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 EPS30699.1 - 1.1e-64 217.4 0.0 1.9e-64 216.6 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 EPS30699.1 - 3.1e-35 120.5 0.0 6.7e-35 119.5 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EPS30699.1 - 2.5e-30 104.6 0.0 6.7e-30 103.2 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 EPS30699.1 - 3.3e-27 95.6 0.0 5.8e-27 94.8 0.0 1.4 1 0 0 1 1 1 1 HMGL-like ATP-grasp_4 PF13535.1 EPS30699.1 - 7.3e-19 68.2 0.2 1.7e-18 66.9 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EPS30699.1 - 1.1e-17 63.3 3.7 1.2e-17 63.2 0.8 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 EPS30699.1 - 2.8e-17 62.4 0.0 8.5e-17 60.8 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 EPS30699.1 - 3e-11 42.7 1.1 2.8e-05 23.7 0.0 3.7 2 1 1 3 3 3 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 EPS30699.1 - 1.6e-10 40.6 0.0 3.1e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EPS30699.1 - 2.5e-07 30.2 0.1 4.8e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EPS30699.1 - 7.5e-06 25.5 0.0 2.2e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EPS30699.1 - 3.3e-05 23.7 0.0 8.5e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 EPS30699.1 - 0.00068 19.9 0.0 0.23 11.8 0.0 3.8 3 1 1 4 4 4 1 HlyD family secretion protein HlyD PF00529.15 EPS30699.1 - 0.0045 16.3 0.0 0.49 9.6 0.0 2.6 2 0 0 2 2 2 1 HlyD family secretion protein GARS_A PF01071.14 EPS30699.1 - 0.048 13.2 0.0 0.09 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DUF4060 PF13269.1 EPS30699.1 - 0.16 11.9 0.8 0.39 10.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4060) Clathrin PF00637.15 EPS30700.1 - 1.3e-201 660.2 34.3 3.9e-34 117.2 0.5 7.4 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_propel PF01394.15 EPS30700.1 - 5.5e-37 123.5 0.4 1.1e-06 28.5 0.0 7.6 7 0 0 7 7 7 7 Clathrin propeller repeat Clathrin_H_link PF13838.1 EPS30700.1 - 2.4e-29 101.0 1.1 6.9e-29 99.5 0.1 2.5 2 0 0 2 2 2 1 Clathrin-H-link TPR_7 PF13176.1 EPS30700.1 - 0.00049 19.6 2.4 31 4.7 0.0 6.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 EPS30700.1 - 0.0098 15.8 3.0 12 5.9 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EPS30700.1 - 0.97 10.2 12.1 58 4.7 0.0 7.6 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_19 PF14559.1 EPS30700.1 - 1.8 8.9 5.7 58 4.1 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat MFS_1 PF07690.11 EPS30701.1 - 1.9e-32 112.3 48.2 3.1e-31 108.3 16.8 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS30701.1 - 1e-28 100.1 24.9 2e-28 99.1 17.3 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter PIRT PF15099.1 EPS30701.1 - 0.31 10.2 4.3 0.12 11.6 0.8 1.9 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Peptidase_A8 PF01252.13 EPS30701.1 - 7.4 6.1 11.9 0.34 10.5 2.5 2.9 3 2 1 4 4 4 0 Signal peptidase (SPase) II TPMT PF05724.6 EPS30702.1 - 5.5e-27 94.6 0.0 7.4e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_18 PF12847.2 EPS30702.1 - 4.4e-06 27.2 0.0 7.3e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPS30702.1 - 8.6e-06 25.4 0.0 0.00011 21.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPS30702.1 - 2.5e-05 24.2 0.0 4e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPS30702.1 - 5.7e-05 22.8 0.0 8.4e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPS30702.1 - 9.4e-05 22.8 0.0 0.00026 21.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPS30702.1 - 0.0018 18.7 0.0 0.0087 16.5 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain N2227 PF07942.7 EPS30702.1 - 0.15 10.9 0.0 0.22 10.4 0.0 1.1 1 0 0 1 1 1 0 N2227-like protein Aegerolysin PF06355.8 EPS30703.1 - 1.2e-41 141.5 0.2 1.5e-41 141.3 0.1 1.0 1 0 0 1 1 1 1 Aegerolysin DUF3425 PF11905.3 EPS30704.1 - 3.3e-32 111.2 1.7 5.2e-32 110.5 1.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) LysM PF01476.15 EPS30705.1 - 4.3e-10 39.3 0.3 8.9e-10 38.3 0.2 1.6 1 0 0 1 1 1 1 LysM domain NmrA PF05368.8 EPS30706.1 - 3.5e-14 52.6 0.0 5.8e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPS30706.1 - 1.4e-10 41.4 0.0 3.8e-10 40.0 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPS30706.1 - 3.1e-06 26.8 0.0 1.7e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EPS30706.1 - 3.1e-05 23.7 0.0 7.4e-05 22.4 0.0 1.7 2 0 0 2 2 2 1 KR domain Semialdhyde_dh PF01118.19 EPS30706.1 - 4.3e-05 23.8 0.2 0.00023 21.4 0.0 2.1 2 1 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 EPS30706.1 - 0.00016 20.6 0.0 0.00023 20.1 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EPS30706.1 - 0.00017 21.5 0.2 0.00032 20.6 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase Saccharop_dh PF03435.13 EPS30706.1 - 0.0029 16.6 0.1 0.0042 16.1 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DapB_N PF01113.15 EPS30706.1 - 0.0033 17.3 0.6 0.064 13.1 0.1 2.3 1 1 1 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.10 EPS30706.1 - 0.0059 15.5 0.1 0.0096 14.8 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Tubulin_2 PF13809.1 EPS30706.1 - 0.052 12.4 0.0 0.082 11.8 0.0 1.2 1 0 0 1 1 1 0 Tubulin like 3Beta_HSD PF01073.14 EPS30706.1 - 0.12 11.0 0.1 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Med27 PF11571.3 EPS30709.1 - 1.1e-18 67.1 0.0 1.9e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 27 Ldh_2 PF02615.9 EPS30709.1 - 0.056 12.1 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 Malate/L-lactate dehydrogenase DUF927 PF06048.6 EPS30709.1 - 0.09 12.0 0.1 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF927) SOG2 PF10428.4 EPS30711.1 - 6.1 5.3 13.0 8.1 4.9 9.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF4470 PF14737.1 EPS30714.1 - 1e-19 70.0 0.1 1.7e-19 69.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 EPS30714.1 - 1.4e-08 34.5 12.4 2.5e-08 33.6 8.6 1.4 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 EPS30714.1 - 1.7 8.3 10.5 3.3 7.4 7.3 1.4 1 0 0 1 1 1 0 HIT zinc finger SNF2_N PF00176.18 EPS30715.1 - 4.6e-72 242.3 0.0 6.9e-72 241.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPS30715.1 - 4.3e-14 52.1 0.0 1.4e-13 50.5 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPS30715.1 - 0.0023 17.4 0.0 0.026 14.0 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase Baculo_PEP_C PF04513.7 EPS30715.1 - 0.079 12.7 0.2 0.18 11.6 0.2 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus HK97-gp10_like PF04883.7 EPS30715.1 - 4.3 8.3 6.7 1.7 9.6 0.0 3.2 3 1 0 3 3 3 0 Bacteriophage HK97-gp10, putative tail-component Pkinase PF00069.20 EPS30716.1 - 1.6e-50 171.6 0.0 4e-50 170.3 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS30716.1 - 1.4e-21 76.7 0.0 2.8e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPS30716.1 - 0.00055 19.7 0.1 0.0014 18.4 0.1 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EPS30716.1 - 0.0092 15.3 0.6 0.062 12.6 0.4 2.1 1 1 0 1 1 1 1 RIO1 family DUF4430 PF14478.1 EPS30716.1 - 0.09 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4430) MLANA PF14991.1 EPS30716.1 - 0.32 11.0 6.3 0.92 9.5 4.4 1.7 1 0 0 1 1 1 0 Protein melan-A eIF-3c_N PF05470.7 EPS30717.1 - 2.3e-178 594.0 27.3 2.3e-178 594.0 18.9 2.7 2 1 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 EPS30717.1 - 4e-13 49.5 2.4 1.9e-12 47.4 0.0 3.2 3 2 0 3 3 3 1 PCI domain ADH_zinc_N_2 PF13602.1 EPS30720.1 - 4.1e-21 76.2 0.0 7.3e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EPS30720.1 - 1.8e-16 59.8 0.4 2.8e-15 55.9 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 EPS30720.1 - 0.015 14.8 0.4 0.023 14.2 0.3 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Epimerase PF01370.16 EPS30720.1 - 0.02 14.3 0.0 0.028 13.8 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 EPS30720.1 - 0.045 13.6 0.0 0.097 12.5 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DFP PF04127.10 EPS30720.1 - 0.096 12.2 0.0 0.24 10.9 0.0 1.6 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein IBR PF01485.16 EPS30722.1 - 6.7e-06 25.8 2.9 6.7e-06 25.8 2.0 4.3 4 1 0 4 4 4 3 IBR domain adh_short PF00106.20 EPS30723.1 - 2.4e-61 206.5 7.9 1.5e-30 106.2 0.3 2.6 3 0 0 3 3 3 2 short chain dehydrogenase MaoC_dehydratas PF01575.14 EPS30723.1 - 1.9e-30 104.7 0.0 4e-30 103.7 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain KR PF08659.5 EPS30723.1 - 1.5e-29 102.9 2.0 2.4e-14 53.4 0.1 2.3 2 0 0 2 2 2 2 KR domain Epimerase PF01370.16 EPS30723.1 - 9.8e-05 21.8 1.3 0.25 10.7 0.0 2.6 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EPS30723.1 - 0.00015 20.9 1.5 0.0018 17.3 0.1 2.7 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Ldh_1_N PF00056.18 EPS30723.1 - 0.03 14.1 0.9 11 5.8 0.5 2.9 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EPS30723.1 - 0.62 9.6 4.9 2.1 7.9 0.7 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PRK PF00485.13 EPS30724.1 - 0.0096 15.5 0.0 0.016 14.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family SRP54 PF00448.17 EPS30724.1 - 0.011 15.2 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ArgK PF03308.11 EPS30724.1 - 0.042 12.6 0.0 0.31 9.7 0.0 2.1 2 0 0 2 2 2 0 ArgK protein Zeta_toxin PF06414.7 EPS30724.1 - 0.058 12.4 0.0 0.16 11.0 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_16 PF13191.1 EPS30724.1 - 0.062 13.2 0.2 0.1 12.5 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain EAP30 PF04157.11 EPS30725.1 - 2.1e-58 197.1 0.0 2.6e-58 196.8 0.0 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family MarR_2 PF12802.2 EPS30725.1 - 0.011 15.4 0.0 0.058 13.0 0.0 2.2 2 0 0 2 2 2 0 MarR family HTH_6 PF01418.12 EPS30725.1 - 0.012 15.2 0.1 0.079 12.7 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family TrmB PF01978.14 EPS30725.1 - 0.027 14.1 0.3 6 6.6 0.1 3.0 2 1 1 3 3 3 0 Sugar-specific transcriptional regulator TrmB Ribosomal_L30_N PF08079.7 EPS30726.1 - 1.5e-26 92.2 16.7 2.6e-26 91.4 11.6 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EPS30726.1 - 4e-17 61.5 2.9 4.6e-17 61.3 1.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e DNA_gyraseB_C PF00986.16 EPS30727.1 - 0.046 13.4 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 DNA gyrase B subunit, carboxyl terminus Zn_clus PF00172.13 EPS30729.1 - 1.6e-08 34.3 9.4 3e-08 33.4 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EPS30729.1 - 3e-05 22.7 0.5 4.4e-05 22.2 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.8 EPS30730.1 - 1.7e-59 201.0 11.2 1.7e-59 201.0 7.8 1.4 2 0 0 2 2 2 1 RTA1 like protein RTA1 PF04479.8 EPS30731.1 - 5.1e-54 183.1 9.9 7e-54 182.7 6.8 1.1 1 0 0 1 1 1 1 RTA1 like protein zf-DHHC PF01529.15 EPS30731.1 - 4.8 6.5 6.5 6.2 6.1 0.4 2.6 1 1 1 2 2 2 0 DHHC palmitoyltransferase MARVEL PF01284.18 EPS30732.1 - 0.096 12.4 7.5 0.14 11.9 5.2 1.2 1 0 0 1 1 1 0 Membrane-associating domain Bac_rhodopsin PF01036.13 EPS30732.1 - 0.13 11.5 5.8 0.17 11.1 4.0 1.1 1 0 0 1 1 1 0 Bacteriorhodopsin-like protein PalH PF08733.5 EPS30732.1 - 0.19 10.5 6.3 0.26 10.0 4.4 1.2 1 0 0 1 1 1 0 PalH/RIM21 DUF4293 PF14126.1 EPS30732.1 - 0.38 10.6 8.3 0.56 10.1 2.2 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4293) Yip1 PF04893.12 EPS30732.1 - 0.55 9.7 9.8 0.73 9.3 6.8 1.1 1 0 0 1 1 1 0 Yip1 domain CopD PF05425.8 EPS30732.1 - 0.59 10.3 8.1 1 9.6 0.3 2.2 1 1 1 2 2 2 0 Copper resistance protein D DUF4233 PF14017.1 EPS30732.1 - 0.59 10.0 8.5 1.4 8.9 1.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4233) DUF805 PF05656.9 EPS30732.1 - 2.4 8.0 9.2 40 4.0 6.4 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF805) DUF4006 PF13179.1 EPS30732.1 - 3.9 7.1 6.8 1.3 8.6 0.1 2.5 2 1 0 2 2 2 0 Family of unknown function (DUF4006) DUF4282 PF14110.1 EPS30732.1 - 4.5 7.5 8.2 1.5 9.0 1.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4282) RDD PF06271.7 EPS30732.1 - 6.9 6.5 10.2 9.6 6.0 2.1 2.1 1 1 1 2 2 2 0 RDD family Cys_Met_Meta_PP PF01053.15 EPS30735.1 - 3.7e-141 469.8 0.0 4.3e-141 469.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EPS30735.1 - 2.4e-06 26.7 0.0 3.8e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EPS30735.1 - 2.7e-05 23.0 0.0 4.8e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.6 EPS30735.1 - 4.5e-05 21.9 0.0 0.00042 18.7 0.0 2.0 1 1 0 1 1 1 1 Methionine gamma-lyase SelA PF03841.8 EPS30735.1 - 0.00031 19.6 0.0 0.00067 18.4 0.0 1.5 1 1 0 1 1 1 1 L-seryl-tRNA selenium transferase DegT_DnrJ_EryC1 PF01041.12 EPS30735.1 - 0.00073 18.6 0.0 0.002 17.2 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.11 EPS30735.1 - 0.00085 18.1 0.0 0.0014 17.4 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 EPS30735.1 - 0.0012 18.0 0.0 0.0039 16.3 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase PigN PF04987.9 EPS30736.1 - 1.3e-172 574.4 31.2 1.8e-172 573.9 21.6 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 EPS30736.1 - 1.9e-13 50.5 0.0 4e-11 42.8 0.0 2.2 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EPS30736.1 - 6.5e-09 35.4 0.1 1.1e-08 34.7 0.1 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 EPS30736.1 - 0.0099 15.2 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Mur_ligase PF01225.20 EPS30736.1 - 0.11 12.6 0.1 7.3 6.7 0.0 2.5 2 0 0 2 2 2 0 Mur ligase family, catalytic domain Csm1 PF12539.3 EPS30737.1 - 4.9e-26 91.0 0.2 1.5e-25 89.5 0.1 1.8 2 0 0 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 DUF3450 PF11932.3 EPS30737.1 - 0.007 15.6 9.2 0.084 12.1 3.7 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF3450) AAA_13 PF13166.1 EPS30737.1 - 0.0076 14.7 5.7 0.0099 14.3 4.0 1.2 1 0 0 1 1 1 1 AAA domain APG6 PF04111.7 EPS30737.1 - 0.057 12.4 7.3 0.098 11.6 5.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 USP8_interact PF08941.5 EPS30737.1 - 0.072 12.4 0.2 0.18 11.1 0.1 1.6 1 0 0 1 1 1 0 USP8 interacting NYD-SP28 PF14772.1 EPS30737.1 - 0.081 13.0 6.4 0.052 13.6 1.7 2.4 1 1 1 2 2 2 0 Sperm tail SbcD_C PF12320.3 EPS30737.1 - 0.087 12.8 3.3 0.26 11.3 2.0 2.1 2 0 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain COG2 PF06148.6 EPS30737.1 - 0.087 12.6 5.0 0.4 10.5 3.3 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Cluap1 PF10234.4 EPS30737.1 - 0.092 11.9 7.1 0.18 11.0 4.9 1.4 1 0 0 1 1 1 0 Clusterin-associated protein-1 Phage_GP20 PF06810.6 EPS30737.1 - 0.11 11.9 7.9 0.059 12.8 2.3 2.6 2 1 1 3 3 3 0 Phage minor structural protein GP20 ADIP PF11559.3 EPS30737.1 - 0.27 11.1 14.3 0.5 10.2 8.9 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding GAS PF13851.1 EPS30737.1 - 0.81 8.8 10.2 0.66 9.1 2.0 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.6 EPS30737.1 - 1.5 7.4 10.1 2.8 6.4 7.0 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Reo_sigmaC PF04582.7 EPS30737.1 - 2.3 7.3 8.2 3.3 6.7 4.0 2.3 2 1 1 3 3 3 0 Reovirus sigma C capsid protein IncA PF04156.9 EPS30737.1 - 2.6 7.6 14.6 1.3 8.6 4.5 2.4 1 1 1 2 2 2 0 IncA protein DUF3138 PF11336.3 EPS30737.1 - 6.8 4.7 11.8 0.28 9.3 4.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) AAA PF00004.24 EPS30738.1 - 1.1e-37 129.2 0.0 2.9e-37 127.8 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EPS30738.1 - 5.3e-06 26.3 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPS30738.1 - 1.1e-05 26.1 0.0 3.8e-05 24.4 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_22 PF13401.1 EPS30738.1 - 2.1e-05 24.6 0.1 0.00066 19.8 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPS30738.1 - 4.9e-05 23.3 0.3 0.00074 19.5 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 EPS30738.1 - 5.1e-05 22.4 0.0 0.0001 21.4 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EPS30738.1 - 8.1e-05 22.6 0.0 0.00021 21.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EPS30738.1 - 8.4e-05 22.3 0.2 0.00081 19.1 0.2 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EPS30738.1 - 0.00022 21.1 0.0 0.00044 20.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EPS30738.1 - 0.0003 20.2 0.2 0.032 13.6 0.1 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EPS30738.1 - 0.00062 19.2 0.0 0.0013 18.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EPS30738.1 - 0.0007 18.8 0.1 0.0013 17.9 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 EPS30738.1 - 0.00077 19.5 0.0 0.0034 17.4 0.0 1.9 2 0 0 2 2 2 1 Sigma-54 interaction domain RNA_helicase PF00910.17 EPS30738.1 - 0.00099 19.2 0.0 0.0027 17.8 0.0 1.9 1 1 0 1 1 1 1 RNA helicase AAA_28 PF13521.1 EPS30738.1 - 0.002 18.1 0.0 0.0059 16.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EPS30738.1 - 0.0033 17.0 0.0 0.0098 15.5 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.1 EPS30738.1 - 0.0043 17.3 0.0 0.01 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 EPS30738.1 - 0.0062 16.1 0.0 0.0098 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EPS30738.1 - 0.0063 15.6 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 EPS30738.1 - 0.012 15.3 0.2 0.059 13.1 0.1 2.1 2 0 0 2 2 2 0 Part of AAA domain Parvo_NS1 PF01057.12 EPS30738.1 - 0.02 13.7 0.0 0.033 13.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 EPS30738.1 - 0.027 13.9 0.0 0.056 12.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Guanylate_kin PF00625.16 EPS30738.1 - 0.032 13.6 0.1 0.96 8.8 0.0 2.9 3 1 0 4 4 4 0 Guanylate kinase ABC_tran PF00005.22 EPS30738.1 - 0.035 14.4 0.0 0.096 12.9 0.0 1.8 1 1 0 1 1 1 0 ABC transporter CPT PF07931.7 EPS30738.1 - 0.052 13.1 0.0 0.099 12.2 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein DUF815 PF05673.8 EPS30738.1 - 0.055 12.3 0.0 0.099 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 EPS30738.1 - 0.061 13.0 0.0 0.21 11.2 0.0 1.7 1 1 1 2 2 2 0 Archaeal ATPase UPF0079 PF02367.12 EPS30738.1 - 0.092 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 SKI PF01202.17 EPS30738.1 - 0.093 12.5 0.0 0.28 11.0 0.0 1.8 1 0 0 1 1 1 0 Shikimate kinase Rad17 PF03215.10 EPS30738.1 - 0.14 10.8 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein COesterase PF00135.23 EPS30740.1 - 1.6e-88 297.7 0.0 2.8e-87 293.6 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EPS30740.1 - 8.2e-06 25.5 0.1 6.4e-05 22.6 0.0 2.4 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EPS30740.1 - 0.00062 19.0 0.0 0.0011 18.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family tRNA_SAD PF07973.9 EPS30741.1 - 1.3e-06 28.1 1.0 2.2e-06 27.4 0.7 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.14 EPS30741.1 - 3.8e-05 22.1 0.0 5.5e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) FKBP_C PF00254.23 EPS30742.1 - 1.9e-25 88.7 0.0 2.2e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PHP PF02811.14 EPS30743.1 - 2.8e-12 46.7 0.0 4.6e-12 46.0 0.0 1.4 1 1 0 1 1 1 1 PHP domain ACPS PF01648.15 EPS30744.1 - 2.1e-13 50.1 0.0 3.4e-13 49.4 0.0 1.3 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily DUF2611 PF11022.3 EPS30745.1 - 6.4e-26 90.2 0.7 6.8e-26 90.1 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) MTP18 PF10558.4 EPS30746.1 - 2.4e-68 228.7 0.0 3.2e-68 228.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) DUF2964 PF11177.3 EPS30746.1 - 0.14 12.1 0.1 0.31 11.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2964) BMF PF15185.1 EPS30747.1 - 2.1 7.5 4.2 0.6 9.3 0.1 2.2 2 0 0 2 2 2 0 Bcl-2-modifying factor, apoptosis NumbF PF06311.7 EPS30748.1 - 0.057 13.5 0.2 0.066 13.3 0.1 1.2 1 0 0 1 1 1 0 NUMB domain DUF605 PF04652.11 EPS30749.1 - 9.5 5.4 15.6 3.5 6.9 2.2 2.1 2 0 0 2 2 2 0 Vta1 like EAP30 PF04157.11 EPS30751.1 - 2e-52 177.5 0.1 2.6e-52 177.2 0.1 1.1 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 EPS30751.1 - 2.9e-28 97.5 0.0 4.7e-28 96.8 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 EPS30751.1 - 0.00024 20.5 0.0 0.0012 18.3 0.0 2.0 2 0 0 2 2 2 1 GRAM domain zf-Sec23_Sec24 PF04810.10 EPS30751.1 - 0.0011 18.5 0.8 0.0011 18.5 0.6 2.4 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger zf-RanBP PF00641.13 EPS30751.1 - 0.0036 16.3 1.2 0.0036 16.3 0.8 2.7 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others GCC2_GCC3 PF07699.8 EPS30751.1 - 0.16 11.5 1.6 0.33 10.5 0.1 2.0 2 0 0 2 2 2 0 GCC2 and GCC3 DZR PF12773.2 EPS30751.1 - 0.41 10.4 5.0 0.27 11.0 0.2 2.4 2 1 0 2 2 2 0 Double zinc ribbon SAC3_GANP PF03399.11 EPS30752.1 - 1.7e-67 226.9 0.3 2.2e-67 226.5 0.2 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EPS30752.1 - 5.5e-06 26.2 0.4 3.8e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 SH3_1 PF00018.23 EPS30754.1 - 1.8e-24 84.8 0.0 6.7e-11 41.4 0.0 2.7 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.1 EPS30754.1 - 7.2e-15 54.3 0.1 5.7e-07 29.0 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 EPS30754.1 - 3.1e-13 49.5 0.0 5.8e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.12 EPS30754.1 - 5.6e-10 38.5 0.0 5.9e-06 25.6 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.19 EPS30754.1 - 1.7e-09 37.2 0.2 3.9e-09 36.0 0.1 1.6 1 0 0 1 1 1 1 PB1 domain AFG1_ATPase PF03969.11 EPS30755.1 - 2.1e-91 306.4 0.0 2.6e-86 289.6 0.0 2.3 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 EPS30755.1 - 0.00023 21.1 0.4 0.49 10.3 0.0 3.1 2 1 1 3 3 3 2 AAA ATPase domain AAA PF00004.24 EPS30755.1 - 0.015 15.4 0.0 0.045 13.9 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPS30755.1 - 0.015 15.4 0.0 0.041 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.13 EPS30755.1 - 0.022 14.3 0.1 0.78 9.3 0.0 2.3 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_5 PF07728.9 EPS30755.1 - 0.043 13.5 0.0 0.09 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EPS30755.1 - 0.054 13.6 0.0 0.19 11.9 0.0 2.0 2 0 0 2 2 2 0 RNA helicase Catalase PF00199.14 EPS30756.1 - 7.6e-158 525.2 0.1 1.1e-157 524.6 0.1 1.3 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EPS30756.1 - 2.2e-17 62.6 0.1 5.1e-17 61.4 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 EPS30756.1 - 2.8e-07 30.1 0.1 5e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EPS30756.1 - 0.087 12.0 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative amidotransferase Amidase PF01425.16 EPS30757.1 - 3.4e-98 329.3 0.0 4e-98 329.1 0.0 1.0 1 0 0 1 1 1 1 Amidase Chitin_synth_1 PF01644.12 EPS30758.1 - 2.5e-86 287.5 0.1 3.9e-86 286.8 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EPS30758.1 - 1.7e-31 107.7 0.4 3.7e-31 106.6 0.3 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EPS30758.1 - 5.7e-22 77.8 1.6 1.4e-19 69.8 0.0 2.4 1 1 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EPS30758.1 - 2.9e-07 30.3 0.8 1.2e-06 28.4 0.6 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EPS30758.1 - 6.4e-05 22.8 0.0 0.00012 21.9 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase like family 2 DUF1774 PF08611.5 EPS30759.1 - 3e-39 133.0 2.4 3e-39 133.0 1.7 2.1 2 1 0 2 2 2 1 Fungal protein of unknown function (DUF1774) Inositol_P PF00459.20 EPS30760.1 - 4.7e-38 131.0 0.3 1.1e-37 129.8 0.2 1.5 1 1 0 1 1 1 1 Inositol monophosphatase family DUF2264 PF10022.4 EPS30761.1 - 3.5e-135 450.3 0.1 6.2e-135 449.5 0.0 1.4 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2264) Cofilin_ADF PF00241.15 EPS30762.1 - 3e-19 69.1 0.0 3.3e-19 69.0 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein zf-AN1 PF01428.11 EPS30763.1 - 6.5e-25 86.7 22.0 5.9e-13 48.4 5.8 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger Transp_Tc5_C PF04236.10 EPS30763.1 - 0.005 17.0 13.0 0.13 12.5 2.9 2.4 2 0 0 2 2 2 2 Tc5 transposase C-terminal domain zf-RING_5 PF14634.1 EPS30763.1 - 0.047 13.4 0.6 0.047 13.4 0.4 2.6 3 0 0 3 3 3 0 zinc-RING finger domain IBR PF01485.16 EPS30763.1 - 0.093 12.6 22.0 0.033 14.0 2.9 2.8 2 1 0 2 2 2 0 IBR domain zinc_ribbon_5 PF13719.1 EPS30763.1 - 0.73 9.4 7.5 1.5 8.5 0.2 2.8 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EPS30763.1 - 0.82 9.4 7.7 1.3 8.8 0.3 2.8 2 0 0 2 2 2 0 zinc-ribbon domain C1_4 PF07975.7 EPS30763.1 - 1.7 8.6 19.3 4.5 7.3 5.5 3.0 2 2 0 2 2 2 0 TFIIH C1-like domain Zn-ribbon_8 PF09723.5 EPS30763.1 - 3.2 7.7 11.0 3.3 7.7 1.6 2.7 2 0 0 2 2 2 0 Zinc ribbon domain PhnA_Zn_Ribbon PF08274.7 EPS30763.1 - 5.1 6.9 7.1 10 6.0 0.5 2.7 2 1 0 2 2 2 0 PhnA Zinc-Ribbon zf-LITAF-like PF10601.4 EPS30763.1 - 7 6.5 9.2 3.2 7.6 0.2 2.4 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain Thymidylat_synt PF00303.14 EPS30764.1 - 1.9e-111 371.4 0.0 2.1e-111 371.2 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase TGT PF01702.13 EPS30765.1 - 4.5e-94 314.1 0.0 5.7e-94 313.8 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase MFS_1 PF07690.11 EPS30766.1 - 7.8e-29 100.4 29.9 1.1e-28 100.0 20.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily TetR PF13972.1 EPS30767.1 - 0.014 14.8 0.0 0.016 14.6 0.0 1.1 1 0 0 1 1 1 0 Bacterial transcriptional repressor DUF1492 PF07374.6 EPS30767.1 - 0.02 15.0 0.1 0.022 14.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1492) RNA_pol_Rpb4 PF03874.11 EPS30767.1 - 0.056 13.4 0.0 0.056 13.4 0.0 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb4 dsrm PF00035.20 EPS30769.1 - 0.0003 21.2 0.0 0.00064 20.2 0.0 1.5 1 1 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.1 EPS30769.1 - 0.00032 20.9 0.1 0.0013 18.9 0.1 1.9 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 R3H-assoc PF13902.1 EPS30774.1 - 2.5e-25 88.9 5.8 2.5e-25 88.9 4.0 2.0 2 1 0 2 2 2 1 R3H-associated N-terminal domain R3H PF01424.17 EPS30774.1 - 0.00034 20.2 0.3 0.0015 18.1 0.2 2.1 1 1 0 1 1 1 1 R3H domain Peptidase_M28 PF04389.12 EPS30775.1 - 1.7e-25 89.7 0.1 3.3e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EPS30775.1 - 7.2e-05 22.3 0.0 0.00013 21.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Ala_racemase_N PF01168.15 EPS30776.1 - 6e-24 84.8 0.1 7.4e-24 84.5 0.1 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.1 EPS30776.1 - 2.7e-19 69.1 0.0 7.2e-19 67.7 0.0 1.8 2 0 0 2 2 2 1 Putative serine dehydratase domain SDH_alpha PF03313.10 EPS30776.1 - 0.00048 19.2 0.4 0.015 14.3 0.1 2.4 2 0 0 2 2 2 1 Serine dehydratase alpha chain GTP_CH_N PF12471.3 EPS30776.1 - 0.08 12.5 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 GTP cyclohydrolase N terminal Pribosyltran PF00156.22 EPS30778.1 - 1.9e-08 34.1 0.1 4.9e-08 32.7 0.0 1.6 1 1 0 1 1 1 1 Phosphoribosyl transferase domain DPM3 PF08285.6 EPS30779.1 - 3.7e-31 106.8 0.1 4e-31 106.7 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) 3HCDH_N PF02737.13 EPS30781.1 - 6.1e-53 179.1 1.1 8.6e-53 178.6 0.8 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EPS30781.1 - 9.9e-34 115.6 0.1 2.7e-33 114.2 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EPS30781.1 - 2.4e-06 27.5 0.1 5.4e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DAO PF01266.19 EPS30781.1 - 0.00065 18.7 0.0 0.00065 18.7 0.0 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Saccharop_dh PF03435.13 EPS30781.1 - 0.0012 17.8 0.1 0.0015 17.5 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_Gly3P_dh_N PF01210.18 EPS30781.1 - 0.0041 16.8 0.2 0.0069 16.1 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 EPS30781.1 - 0.011 14.9 0.3 0.037 13.1 0.2 1.9 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EPS30781.1 - 0.042 14.2 0.1 0.096 13.0 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPS30781.1 - 0.043 13.6 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 EPS30781.1 - 0.075 13.4 1.4 0.21 12.0 0.7 2.0 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 EPS30781.1 - 0.092 12.7 0.1 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_3 PF13738.1 EPS30781.1 - 0.1 12.6 1.3 0.41 10.6 0.7 1.9 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TIMELESS PF04821.9 EPS30782.1 - 2.1e-89 299.3 0.4 6.4e-89 297.7 0.3 1.9 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.8 EPS30782.1 - 1.1e-54 186.3 30.4 2.4e-53 181.9 0.3 4.2 2 1 1 3 3 3 2 Timeless protein C terminal region PhzC-PhzF PF02567.11 EPS30783.1 - 7.8e-45 153.2 0.1 9.9e-45 152.9 0.1 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein DUF1857 PF08982.6 EPS30784.1 - 1.2e-35 122.2 0.0 1.4e-35 122.1 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1857) Acetyltransf_1 PF00583.19 EPS30785.1 - 5.5e-05 23.1 0.0 8.3e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPS30785.1 - 0.00019 21.5 0.0 0.00029 20.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPS30785.1 - 0.0029 17.7 0.0 0.0063 16.6 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPS30785.1 - 0.043 13.5 0.0 0.093 12.4 0.0 1.5 1 1 0 1 1 1 0 FR47-like protein CobU PF02283.11 EPS30785.1 - 0.088 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Zn_clus PF00172.13 EPS30788.1 - 6.6e-09 35.5 13.1 6.6e-09 35.5 9.1 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Homeobox PF00046.24 EPS30789.1 - 8.1e-17 60.5 3.9 2.4e-16 59.0 2.7 1.8 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EPS30789.1 - 0.04 13.6 0.2 0.091 12.4 0.1 1.6 1 0 0 1 1 1 0 Homeobox KN domain efThoc1 PF11957.3 EPS30792.1 - 1.6e-172 574.4 0.0 2e-172 574.1 0.0 1.0 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor AAA_12 PF13087.1 EPS30793.1 - 6.5e-26 90.9 0.0 1.2e-25 90.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EPS30793.1 - 1e-23 84.2 0.0 1.8e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPS30793.1 - 1.8e-10 40.4 0.1 1.1e-09 37.8 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain ResIII PF04851.10 EPS30793.1 - 6.4e-06 26.1 0.0 1.4e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EPS30793.1 - 1e-05 25.2 0.0 0.0016 18.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EPS30793.1 - 0.00011 21.7 0.0 0.095 12.2 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA PF00004.24 EPS30793.1 - 0.00045 20.4 0.0 0.0018 18.4 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EPS30793.1 - 0.00065 19.1 0.0 0.0015 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EPS30793.1 - 0.0013 18.2 0.0 0.0055 16.2 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EPS30793.1 - 0.0017 18.4 0.0 0.005 16.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.10 EPS30793.1 - 0.0048 15.8 0.1 1.3 7.8 0.0 3.1 3 0 0 3 3 3 1 DnaB-like helicase C terminal domain AAA_17 PF13207.1 EPS30793.1 - 0.0048 17.7 0.0 0.2 12.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 EPS30793.1 - 0.024 13.7 0.0 0.07 12.2 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.4 EPS30793.1 - 0.03 13.2 0.8 0.05 12.5 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.1 EPS30793.1 - 0.042 13.7 0.0 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EPS30793.1 - 0.042 13.5 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) UvrD-helicase PF00580.16 EPS30793.1 - 0.055 12.7 0.0 0.14 11.4 0.0 1.7 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain SMC_N PF02463.14 EPS30793.1 - 0.059 12.5 0.0 0.089 12.0 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_33 PF13671.1 EPS30793.1 - 0.063 13.1 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EPS30793.1 - 0.097 12.3 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase UvrD_C_2 PF13538.1 EPS30793.1 - 0.1 12.7 0.1 0.41 10.8 0.0 2.1 2 0 0 2 2 1 0 UvrD-like helicase C-terminal domain RNA_helicase PF00910.17 EPS30793.1 - 0.19 11.9 0.0 0.48 10.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase KaiC PF06745.8 EPS30793.1 - 0.21 10.7 0.0 0.41 9.7 0.0 1.4 1 0 0 1 1 1 0 KaiC 4HBT PF03061.17 EPS30794.1 - 7.6e-13 48.3 0.1 1.1e-12 47.8 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EPS30794.1 - 0.07 12.8 0.0 0.078 12.7 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily DUF4442 PF14539.1 EPS30794.1 - 0.13 12.2 0.1 0.19 11.7 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4442) Tfb2 PF03849.9 EPS30795.1 - 6.5e-142 472.5 0.0 1.6e-141 471.2 0.0 1.5 2 0 0 2 2 2 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 EPS30795.1 - 5.2e-06 26.2 0.0 7e-05 22.5 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SinI PF08671.5 EPS30795.1 - 0.0071 15.7 0.0 0.029 13.7 0.0 2.0 2 0 0 2 2 2 1 Anti-repressor SinI DUF4006 PF13179.1 EPS30796.1 - 0.023 14.2 0.4 0.023 14.2 0.3 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF4006) DUF3431 PF11913.3 EPS30797.1 - 2.8e-72 242.8 0.0 3.5e-72 242.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) DUF1096 PF06493.6 EPS30798.1 - 3.6 7.6 42.2 0.78 9.7 12.1 3.2 1 1 3 4 4 4 0 Protein of unknown function (DUF1096) Adaptin_N PF01602.15 EPS30799.1 - 5.8e-125 417.5 3.4 7.4e-125 417.2 2.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 EPS30799.1 - 2.5e-43 146.6 0.0 5.6e-43 145.4 0.0 1.6 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 EPS30799.1 - 7.4e-19 68.1 0.0 1.9e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain Ala_racemase_N PF01168.15 EPS30800.1 - 2.4e-45 154.7 0.1 5e-45 153.7 0.1 1.5 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain Hist_deacetyl PF00850.14 EPS30803.1 - 2.1e-59 201.3 0.0 3.3e-59 200.7 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain RTP801_C PF07809.6 EPS30803.1 - 0.17 11.5 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 RTP801 C-terminal region SLAC1 PF03595.12 EPS30805.1 - 7.6e-76 254.8 46.8 8.7e-76 254.6 32.4 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel CaKB PF03185.10 EPS30805.1 - 4.8 6.4 7.7 0.18 11.1 0.4 2.2 2 1 1 3 3 3 0 Calcium-activated potassium channel, beta subunit APH PF01636.18 EPS30806.1 - 1.6e-22 80.3 0.0 1.7e-10 41.0 0.0 2.8 2 1 0 2 2 2 2 Phosphotransferase enzyme family zf-AN1 PF01428.11 EPS30806.1 - 9.1e-08 31.8 24.5 0.00057 19.7 7.6 2.5 2 0 0 2 2 2 2 AN1-like Zinc finger DUF3435 PF11917.3 EPS30807.1 - 1.2e-13 50.6 1.8 1.2e-13 50.5 1.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) CtIP_N PF10482.4 EPS30807.1 - 0.027 14.2 1.4 0.04 13.6 1.0 1.2 1 0 0 1 1 1 0 Tumour-suppressor protein CtIP N-terminal domain DUF812 PF05667.6 EPS30807.1 - 0.028 12.9 0.9 0.032 12.7 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Trans_reg_C PF00486.23 EPS30807.1 - 0.049 13.5 0.1 0.07 13.0 0.1 1.2 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal DUF3435 PF11917.3 EPS30808.1 - 2.5e-09 36.3 0.0 3.3e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3435) adh_short PF00106.20 EPS30809.1 - 7.3e-23 81.3 0.0 1e-22 80.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPS30809.1 - 5e-17 62.4 0.0 6.3e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EPS30809.1 - 1.4e-05 24.3 0.0 0.00013 21.2 0.0 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.8 EPS30809.1 - 0.00011 21.5 0.3 0.0036 16.6 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 EPS30809.1 - 0.00083 19.4 0.1 0.0015 18.6 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPS30809.1 - 0.035 13.5 0.0 0.065 12.6 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GARS_C PF02843.11 EPS30809.1 - 0.053 13.6 0.1 0.2 11.8 0.0 1.9 2 1 1 3 3 3 0 Phosphoribosylglycinamide synthetase, C domain LacI PF00356.16 EPS30809.1 - 0.091 12.3 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, lacI family ADH_zinc_N PF00107.21 EPS30809.1 - 0.11 12.0 0.1 0.68 9.4 0.0 2.0 2 0 0 2 2 2 0 Zinc-binding dehydrogenase MGS PF02142.17 EPS30809.1 - 0.14 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 MGS-like domain ATP-grasp_2 PF08442.5 EPS30810.1 - 1.2e-77 259.9 0.6 1.2e-77 259.9 0.4 1.6 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.14 EPS30810.1 - 2.3e-25 88.9 0.3 5.2e-25 87.8 0.2 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 EPS30810.1 - 1e-06 28.1 0.2 2.7e-06 26.7 0.2 1.7 1 0 0 1 1 1 1 ATP-grasp domain Peripla_BP_2 PF01497.13 EPS30810.1 - 0.0002 20.6 0.3 0.00057 19.0 0.2 1.8 1 0 0 1 1 1 1 Periplasmic binding protein GARS_A PF01071.14 EPS30810.1 - 0.00021 20.9 2.2 0.005 16.4 0.2 2.9 2 1 1 3 3 3 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 EPS30810.1 - 0.0034 17.1 0.0 0.0081 15.9 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.6 EPS30810.1 - 0.0063 16.0 0.0 0.063 12.7 0.0 2.4 2 1 0 2 2 2 1 RimK-like ATP-grasp domain Succ_CoA_lig PF13607.1 EPS30810.1 - 0.036 13.6 0.2 10 5.7 0.0 2.6 1 1 1 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain ATPgrasp_Ter PF15632.1 EPS30810.1 - 0.066 11.9 0.0 0.15 10.7 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon F-box PF00646.28 EPS30811.1 - 1.2e-07 31.2 2.0 3.1e-07 29.8 1.4 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EPS30811.1 - 9.1e-05 22.1 1.2 0.00019 21.0 0.8 1.6 1 0 0 1 1 1 1 F-box-like Med3 PF11593.3 EPS30811.1 - 3.8 6.6 11.4 5.9 6.0 7.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal HSF_DNA-bind PF00447.12 EPS30812.1 - 2.7e-35 120.6 0.3 4.2e-35 120.0 0.2 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding DUF3245 PF11595.3 EPS30813.1 - 7.8e-48 162.5 8.4 7.8e-48 162.5 5.9 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF3245) Vps51 PF08700.6 EPS30813.1 - 0.064 13.1 0.5 0.16 11.8 0.1 2.1 2 1 0 2 2 2 0 Vps51/Vps67 HA2 PF04408.18 EPS30814.1 - 1e-14 54.3 0.1 2.5e-14 53.1 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EPS30814.1 - 1.8e-13 50.1 0.0 1.1e-11 44.4 0.0 3.1 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPS30814.1 - 1e-07 31.5 0.0 2.4e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 EPS30814.1 - 0.00083 19.1 0.0 0.0029 17.4 0.0 1.8 1 1 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Oxidored-like PF09791.4 EPS30815.1 - 5.7e-26 89.7 3.8 1.1e-25 88.8 2.7 1.5 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DUF566 PF04484.7 EPS30815.1 - 0.29 10.6 6.7 0.41 10.1 4.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) Macoilin PF09726.4 EPS30816.1 - 0.02 13.2 2.9 0.026 12.8 2.0 1.1 1 0 0 1 1 1 0 Transmembrane protein Actin PF00022.14 EPS30817.1 - 2.6e-106 355.3 0.0 3.2e-106 355.0 0.0 1.0 1 0 0 1 1 1 1 Actin zf-CCHC PF00098.18 EPS30818.1 - 0.024 14.5 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 Zinc knuckle GCIP PF13324.1 EPS30819.1 - 1.9e-12 47.0 0.5 1.9e-12 47.0 0.4 2.4 1 1 1 2 2 2 1 Grap2 and cyclin-D-interacting OHCU_decarbox PF09349.5 EPS30819.1 - 0.0028 17.9 0.0 0.0081 16.4 0.0 1.8 1 0 0 1 1 1 1 OHCU decarboxylase Med11 PF10280.4 EPS30819.1 - 0.0067 16.4 0.2 0.16 11.9 0.1 2.4 2 0 0 2 2 2 1 Mediator complex protein PEX11 PF05648.9 EPS30819.1 - 0.019 14.2 0.4 0.16 11.2 0.0 2.4 3 0 0 3 3 3 0 Peroxisomal biogenesis factor 11 (PEX11) DUF2457 PF10446.4 EPS30819.1 - 0.42 9.2 7.7 0.89 8.2 5.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) LRR_4 PF12799.2 EPS30820.1 - 2e-36 123.0 43.2 5.7e-07 29.0 1.7 10.4 7 2 4 11 11 11 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPS30820.1 - 1.1e-29 101.8 42.8 2.8e-06 26.9 1.4 8.8 3 2 8 11 11 11 10 Leucine rich repeat LRR_1 PF00560.28 EPS30820.1 - 1.3e-15 54.9 51.9 0.11 12.5 0.3 15.2 14 3 1 15 15 15 6 Leucine Rich Repeat LRR_7 PF13504.1 EPS30820.1 - 1.4e-12 45.5 45.0 0.52 10.7 0.2 14.6 16 0 0 16 16 16 5 Leucine rich repeat LRR_6 PF13516.1 EPS30820.1 - 8.6e-06 25.3 49.1 5.8 7.2 0.1 13.8 12 2 3 15 15 15 4 Leucine Rich repeat LRR_9 PF14580.1 EPS30820.1 - 0.5 9.9 14.9 1.2 8.7 0.0 4.2 2 1 4 6 6 6 0 Leucine-rich repeat Ras_bdg_2 PF14847.1 EPS30821.1 - 0.097 12.6 0.7 0.73 9.7 0.3 2.3 1 1 1 2 2 2 0 Ras-binding domain of Byr2 Ribosomal_L13e PF01294.13 EPS30822.1 - 3.3e-66 222.1 5.6 3.3e-66 222.1 3.9 1.4 1 1 0 1 1 1 1 Ribosomal protein L13e FAM60A PF15396.1 EPS30822.1 - 0.13 12.0 0.3 0.13 12.0 0.2 1.6 2 0 0 2 2 2 0 Protein Family FAM60A Asp-B-Hydro_N PF05279.6 EPS30823.1 - 7 6.4 10.3 7.5 6.3 7.2 1.0 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region zf-C2H2 PF00096.21 EPS30825.1 - 0.009 16.3 1.4 1.2 9.6 0.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2HC_2 PF13913.1 EPS30825.1 - 0.07 12.8 1.5 0.18 11.5 1.0 1.8 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.1 EPS30825.1 - 7.6 7.1 14.7 0.36 11.2 0.5 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger ABC1 PF03109.11 EPS30828.1 - 2.2e-21 76.0 0.0 2.9e-11 43.3 0.0 3.0 3 0 0 3 3 3 2 ABC1 family RIO1 PF01163.17 EPS30828.1 - 0.11 11.8 0.0 0.5 9.6 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Cyto_heme_lyase PF01265.12 EPS30829.1 - 6.3e-83 278.3 0.0 7.8e-83 278.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase Fungal_trans_2 PF11951.3 EPS30831.1 - 2.2e-12 46.2 0.2 3.3e-12 45.6 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tricorn_C1 PF14684.1 EPS30831.1 - 0.053 13.4 1.3 0.12 12.3 0.9 1.5 1 0 0 1 1 1 0 Tricorn protease C1 domain SBF2 PF12335.3 EPS30831.1 - 0.1 11.9 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Myotubularin protein DNA_pol_viral_N PF00242.12 EPS30831.1 - 1.5 7.7 10.0 2 7.3 6.9 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain UQ_con PF00179.21 EPS30832.1 - 1.1e-25 89.7 0.1 1.5e-25 89.2 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Bac_surface_Ag PF01103.18 EPS30833.1 - 4.5e-39 134.7 0.0 5.7e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Surface antigen Yip1 PF04893.12 EPS30834.1 - 0.00024 20.6 23.3 0.0031 17.0 15.8 2.4 1 1 0 1 1 1 1 Yip1 domain UFD1 PF03152.9 EPS30835.1 - 1.8e-23 82.5 0.0 2e-19 69.3 0.0 3.0 2 1 0 2 2 2 2 Ubiquitin fusion degradation protein UFD1 zf-C2H2_6 PF13912.1 EPS30835.1 - 0.0076 16.1 0.0 0.0076 16.1 0.0 3.9 4 0 0 4 4 4 1 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 EPS30835.1 - 6.5 6.7 9.8 6.3 6.8 0.2 3.9 4 0 0 4 4 4 0 Zinc ribbon domain Auto_anti-p27 PF06677.7 EPS30837.1 - 0.12 12.1 0.1 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) AAA PF00004.24 EPS30838.1 - 1.8e-43 147.9 0.0 2.9e-43 147.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EPS30838.1 - 5.2e-08 32.7 0.0 1.4e-07 31.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EPS30838.1 - 2.2e-07 30.9 0.0 4.2e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EPS30838.1 - 2.4e-06 27.6 0.1 2.1e-05 24.6 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EPS30838.1 - 4e-06 27.0 0.1 0.00023 21.2 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPS30838.1 - 9.8e-05 23.1 0.0 0.00023 21.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPS30838.1 - 0.00013 21.6 0.1 0.00028 20.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EPS30838.1 - 0.00013 21.0 0.0 0.00024 20.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EPS30838.1 - 0.00039 19.8 0.0 0.00073 19.0 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EPS30838.1 - 0.0011 17.7 0.0 0.0021 16.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EPS30838.1 - 0.0016 18.3 0.0 0.0032 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EPS30838.1 - 0.0022 17.9 0.0 0.0035 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EPS30838.1 - 0.0028 16.7 0.0 0.0051 15.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 EPS30838.1 - 0.0038 17.1 0.0 0.0066 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EPS30838.1 - 0.0039 16.7 0.0 0.011 15.3 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 EPS30838.1 - 0.0056 15.8 0.0 0.017 14.2 0.0 1.8 2 0 0 2 2 2 1 KaiC Mg_chelatase PF01078.16 EPS30838.1 - 0.0057 15.8 0.1 0.015 14.4 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EPS30838.1 - 0.0065 16.7 0.0 0.03 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EPS30838.1 - 0.019 14.5 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EPS30838.1 - 0.02 14.3 0.0 0.096 12.1 0.0 2.1 3 0 0 3 3 3 0 Sigma-54 interaction domain PhoH PF02562.11 EPS30838.1 - 0.021 14.0 0.0 0.076 12.2 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein DUF815 PF05673.8 EPS30838.1 - 0.021 13.7 0.0 0.037 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 EPS30838.1 - 0.024 14.0 0.1 0.065 12.6 0.1 1.8 1 1 0 1 1 1 0 AAA domain DUF2072 PF09845.4 EPS30838.1 - 0.033 14.1 0.1 0.082 12.8 0.1 1.6 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) RNA_helicase PF00910.17 EPS30838.1 - 0.034 14.3 0.0 0.066 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.12 EPS30838.1 - 0.051 12.4 0.0 0.083 11.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 EPS30838.1 - 0.051 13.6 0.0 0.18 11.8 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.17 EPS30838.1 - 0.082 11.7 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Histone PF00125.19 EPS30838.1 - 0.1 12.7 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 NACHT PF05729.7 EPS30838.1 - 0.13 11.8 0.0 0.52 9.9 0.0 1.9 2 0 0 2 2 2 0 NACHT domain Na_Ca_ex PF01699.19 EPS30839.1 - 5e-30 103.9 23.1 2.5e-18 66.0 6.7 4.2 5 0 0 5 5 5 2 Sodium/calcium exchanger protein DUF307 PF03733.8 EPS30839.1 - 6.8e-14 52.0 8.3 6.8e-14 52.0 5.8 3.9 4 0 0 4 4 4 2 Domain of unknown function (DUF307) FGGY_C PF02782.11 EPS30840.1 - 4.8e-52 176.4 0.1 7.6e-52 175.8 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EPS30840.1 - 5.3e-23 81.5 0.0 4.7e-20 71.9 0.0 2.3 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain F-box PF00646.28 EPS30842.1 - 0.00036 20.1 0.2 0.00078 19.0 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 EPS30842.1 - 0.016 14.9 0.9 0.037 13.7 0.1 2.0 3 0 0 3 3 3 0 F-box-like domain F-box-like PF12937.2 EPS30842.1 - 0.059 13.1 0.2 0.14 11.8 0.2 1.7 1 0 0 1 1 1 0 F-box-like Y_phosphatase PF00102.22 EPS30843.1 - 9.6e-60 201.8 0.0 1.5e-58 197.8 0.0 2.2 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 EPS30843.1 - 2.7e-09 37.3 0.0 1.5e-08 34.9 0.0 2.2 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase3 PF13350.1 EPS30843.1 - 0.0027 17.9 0.3 0.013 15.7 0.1 2.2 1 1 1 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 EPS30843.1 - 0.0057 16.2 0.1 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain COX16 PF14138.1 EPS30844.1 - 2.3e-30 104.5 0.1 3e-30 104.2 0.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Nic96 PF04097.9 EPS30845.1 - 1.4e-207 690.6 0.0 1.7e-207 690.3 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.1 EPS30845.1 - 1.1e-09 38.5 40.3 1.1e-09 38.5 27.9 2.6 2 0 0 2 2 2 1 Nucleoporin FG repeat region RibD_C PF01872.12 EPS30846.1 - 1e-31 110.1 0.0 1.4e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 RibD C-terminal domain RCC1 PF00415.13 EPS30847.1 - 2.4e-54 181.3 0.0 1.8e-11 44.0 0.0 8.0 7 2 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EPS30847.1 - 6.9e-33 111.5 37.3 6e-08 32.0 1.0 6.6 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Swi3 PF07962.7 EPS30848.1 - 7.4e-33 112.0 0.6 1.2e-32 111.3 0.4 1.4 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 RGCC PF15151.1 EPS30848.1 - 0.097 13.1 0.8 1.3 9.4 0.5 2.5 1 1 0 1 1 1 0 Response gene to complement 32 protein family NADH-u_ox-rdase PF10785.4 EPS30849.1 - 3.6e-35 120.0 0.2 5.6e-35 119.4 0.2 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 EPS30849.1 - 6.8e-34 115.4 0.0 1e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit dCMP_cyt_deam_1 PF00383.17 EPS30850.1 - 9.6e-25 86.1 0.0 1.7e-24 85.3 0.0 1.4 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region XOO_2897-deam PF14440.1 EPS30850.1 - 0.0047 16.6 0.0 0.007 16.0 0.0 1.3 1 0 0 1 1 1 1 Xanthomonas XOO_2897-like deaminase Bd3614-deam PF14439.1 EPS30850.1 - 0.17 11.7 0.8 0.46 10.3 0.1 1.8 1 1 1 2 2 2 0 Bd3614-like deaminase PI3_PI4_kinase PF00454.22 EPS30851.1 - 3.6e-49 167.3 0.2 7.7e-49 166.2 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 EPS30851.1 - 2.7e-46 158.1 1.3 6.4e-46 156.9 0.0 2.4 3 0 0 3 3 3 1 FAT domain UME PF08064.8 EPS30851.1 - 8.8e-39 131.7 0.2 3e-38 130.0 0.1 2.1 1 0 0 1 1 1 1 UME (NUC010) domain FATC PF02260.15 EPS30851.1 - 4.9e-15 54.6 0.0 1.4e-14 53.2 0.0 1.8 1 0 0 1 1 1 1 FATC domain TPR_11 PF13414.1 EPS30851.1 - 1.1e-05 25.0 2.0 0.55 9.9 0.0 3.9 2 1 1 3 3 3 3 TPR repeat TPR_14 PF13428.1 EPS30851.1 - 0.00046 20.5 1.6 8 7.4 0.0 5.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EPS30851.1 - 0.0041 17.7 2.4 2.2 9.0 0.1 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EPS30851.1 - 0.0055 16.4 1.6 11 6.1 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EPS30851.1 - 0.0062 16.8 1.0 1.8 8.9 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat RRM_1 PF00076.17 EPS30852.1 - 6.1e-15 54.6 0.0 8.5e-15 54.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS30852.1 - 2.8e-11 43.2 0.0 4.2e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS30852.1 - 1.1e-07 31.5 0.0 1.7e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EPS30852.1 - 0.00039 20.2 0.0 0.00062 19.5 0.0 1.2 1 0 0 1 1 1 1 RNA binding motif DUF1777 PF08648.7 EPS30852.1 - 6.2 6.5 66.5 0.065 12.9 15.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) AAA PF00004.24 EPS30853.1 - 7e-66 220.4 0.0 8.1e-42 142.5 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EPS30853.1 - 1.1e-13 51.5 0.2 0.0006 19.8 0.0 4.0 2 2 1 3 3 3 3 AAA ATPase domain AAA_5 PF07728.9 EPS30853.1 - 3.9e-09 36.3 0.4 0.0031 17.2 0.1 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EPS30853.1 - 2.6e-08 34.0 2.7 0.014 15.4 0.1 4.5 2 2 0 2 2 2 2 AAA domain Bac_DnaA PF00308.13 EPS30853.1 - 4.8e-07 29.6 0.0 1.1e-05 25.1 0.0 2.7 2 2 0 2 2 2 1 Bacterial dnaA protein AAA_14 PF13173.1 EPS30853.1 - 5.1e-07 29.6 0.0 0.022 14.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 EPS30853.1 - 6.5e-06 25.3 0.0 0.022 13.8 0.0 3.8 3 1 1 4 4 4 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 EPS30853.1 - 7.1e-06 25.5 0.7 0.64 9.3 0.0 4.3 3 1 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 EPS30853.1 - 1e-05 25.3 0.7 0.0041 16.8 0.1 3.3 2 2 0 2 2 2 1 Archaeal ATPase AAA_28 PF13521.1 EPS30853.1 - 1.7e-05 24.8 0.0 0.08 12.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EPS30853.1 - 2e-05 25.3 0.0 0.44 11.3 0.0 3.0 2 1 0 2 2 2 2 AAA domain TIP49 PF06068.8 EPS30853.1 - 4.8e-05 22.2 0.7 0.026 13.2 0.0 2.5 3 0 0 3 3 3 2 TIP49 C-terminus AAA_2 PF07724.9 EPS30853.1 - 5e-05 23.2 0.0 0.0065 16.4 0.0 2.9 2 2 0 2 2 2 1 AAA domain (Cdc48 subfamily) Rad17 PF03215.10 EPS30853.1 - 0.00013 20.8 0.1 0.0012 17.5 0.0 2.2 2 1 1 3 3 3 1 Rad17 cell cycle checkpoint protein DUF815 PF05673.8 EPS30853.1 - 0.0002 20.4 0.0 0.19 10.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) RNA_helicase PF00910.17 EPS30853.1 - 0.00021 21.4 0.0 1.1 9.4 0.0 2.6 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.12 EPS30853.1 - 0.00023 20.6 0.0 0.41 10.0 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 EPS30853.1 - 0.0007 19.3 0.1 3.5 7.4 0.0 3.5 4 0 0 4 4 3 2 Part of AAA domain Sigma54_activ_2 PF14532.1 EPS30853.1 - 0.0026 17.7 0.0 0.72 9.9 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.7 EPS30853.1 - 0.0031 17.1 1.8 0.11 12.1 0.2 3.5 2 2 2 4 4 4 1 NACHT domain Mg_chelatase PF01078.16 EPS30853.1 - 0.0052 15.9 0.1 2.7 7.1 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EPS30853.1 - 0.0068 16.0 0.7 0.47 9.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EPS30853.1 - 0.0083 15.2 0.0 1.4 7.9 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin ABC_tran PF00005.22 EPS30853.1 - 0.057 13.7 0.1 7.1 6.9 0.0 2.8 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.1 EPS30853.1 - 0.076 12.8 0.0 6.7 6.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EPS30853.1 - 0.079 13.2 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EPS30853.1 - 0.093 11.8 0.6 5.5 6.0 0.1 2.9 2 2 0 2 2 2 0 KaiC ATP-synt_ab PF00006.20 EPS30853.1 - 0.12 11.8 0.0 9.1 5.7 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain UPF0079 PF02367.12 EPS30853.1 - 0.13 11.8 0.1 9.3 5.9 0.0 2.9 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 Viral_helicase1 PF01443.13 EPS30853.1 - 0.15 11.5 0.2 34 3.8 0.0 3.0 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase Ras PF00071.17 EPS30854.1 - 1.2e-65 219.8 0.1 1.4e-65 219.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPS30854.1 - 7.6e-19 68.3 0.0 1e-18 67.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPS30854.1 - 3.6e-14 52.3 0.0 4.6e-14 52.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EPS30854.1 - 8.6e-07 28.5 0.0 1.4e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EPS30854.1 - 1.6e-06 27.4 0.0 2e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EPS30854.1 - 0.0042 17.0 0.0 0.0058 16.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EPS30854.1 - 0.021 14.0 0.0 0.024 13.8 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EPS30854.1 - 0.021 14.0 0.0 0.099 11.9 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF258 PF03193.11 EPS30854.1 - 0.042 13.0 0.1 0.17 11.0 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA PF00004.24 EPS30854.1 - 0.085 13.0 0.0 5.9 7.1 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EPS30854.1 - 0.095 12.2 0.0 0.29 10.6 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EPS30854.1 - 0.12 12.5 0.0 0.29 11.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain NCA2 PF08637.5 EPS30855.1 - 9.4e-82 274.1 0.0 1.6e-81 273.4 0.0 1.4 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 FA_hydroxylase PF04116.8 EPS30856.1 - 4.1e-16 59.4 18.8 4.1e-16 59.4 13.0 1.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily zf-A20 PF01754.11 EPS30858.1 - 0.017 14.6 0.1 0.04 13.5 0.0 1.7 1 0 0 1 1 1 0 A20-like zinc finger Condensin2nSMC PF12422.3 EPS30858.1 - 0.1 12.3 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit zf-CCHC PF00098.18 EPS30858.1 - 0.14 12.1 2.7 0.33 10.9 1.8 1.7 1 0 0 1 1 1 0 Zinc knuckle rve PF00665.21 EPS30859.1 - 2.5e-18 66.3 0.0 4.3e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 EPS30859.1 - 0.028 13.9 0.0 0.072 12.6 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain Potass_KdpF PF09604.5 EPS30860.1 - 2.4 8.1 4.3 4.5 7.2 3.0 1.4 1 0 0 1 1 1 0 F subunit of K+-transporting ATPase (Potass_KdpF) PPR_1 PF12854.2 EPS30861.1 - 0.038 13.4 0.1 0.061 12.8 0.1 1.4 1 1 0 1 1 1 0 PPR repeat UBN2_3 PF14244.1 EPS30862.1 - 0.0011 18.5 0.0 0.0021 17.6 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type FANCI_S2 PF14676.1 EPS30862.1 - 0.041 13.7 0.3 0.4 10.5 0.0 2.1 2 0 0 2 2 2 0 FANCI solenoid 2 Glyco_hydro_57 PF03065.10 EPS30862.1 - 0.056 12.3 0.1 0.085 11.7 0.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 DUF4209 PF13910.1 EPS30862.1 - 0.064 13.3 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4209) Sigma_1s PF02454.11 EPS30862.1 - 0.085 12.6 0.1 0.25 11.1 0.0 1.8 2 0 0 2 2 2 0 Sigma 1s protein HTH_psq PF05225.11 EPS30863.1 - 1.4e-09 37.3 0.0 1.9e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_28 PF13518.1 EPS30863.1 - 0.12 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4419 PF14388.1 EPS30864.1 - 0.045 12.9 1.7 0.051 12.7 1.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4419) DUF3348 PF11828.3 EPS30864.1 - 0.07 12.5 0.7 0.072 12.4 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3348) Phage_capsid PF05065.8 EPS30864.1 - 0.11 11.6 6.6 0.12 11.5 4.6 1.0 1 0 0 1 1 1 0 Phage capsid family DUF3439 PF11921.3 EPS30864.1 - 0.63 9.8 8.0 0.66 9.7 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.12 EPS30864.1 - 3.1 7.5 17.1 3.3 7.4 11.8 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein YpjP PF14005.1 EPS30865.1 - 0.028 14.1 0.3 0.031 14.0 0.2 1.1 1 0 0 1 1 1 0 YpjP-like protein Mor PF08765.6 EPS30865.1 - 0.08 12.7 3.1 0.65 9.7 0.4 2.1 1 1 1 2 2 2 0 Mor transcription activator family Flexi_CP PF00286.15 EPS30865.1 - 0.23 11.1 4.0 0.25 11.0 2.8 1.1 1 0 0 1 1 1 0 Viral coat protein Euplotes_phero PF05842.6 EPS30865.1 - 0.89 9.9 5.4 1.1 9.6 3.8 1.1 1 0 0 1 1 1 0 Euplotes octocarinatus mating pheromone protein DUF3596 PF12167.3 EPS30865.1 - 3 7.4 7.0 35 4.0 4.8 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3596) XK-related PF09815.4 EPS30866.1 - 0.033 13.1 0.0 0.051 12.5 0.0 1.2 1 0 0 1 1 1 0 XK-related protein Phe_ZIP PF08916.6 EPS30866.1 - 0.059 13.6 0.0 0.34 11.2 0.0 2.2 2 0 0 2 2 2 0 Phenylalanine zipper FGF-BP1 PF06473.7 EPS30866.1 - 0.64 9.5 3.6 0.25 10.9 0.1 2.0 2 0 0 2 2 2 0 FGF binding protein 1 (FGF-BP1) RNA_pol_N PF01194.12 EPS30867.1 - 7.8e-30 102.6 1.9 9.2e-30 102.4 1.3 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit WD40 PF00400.27 EPS30868.1 - 2e-06 27.4 15.2 4.6e-05 23.1 0.1 6.6 6 1 0 6 6 6 2 WD domain, G-beta repeat Clr5 PF14420.1 EPS30869.1 - 9.9e-21 73.3 2.9 9.9e-21 73.3 2.0 2.1 2 0 0 2 2 2 1 Clr5 domain Mito_fiss_reg PF05308.6 EPS30869.1 - 0.0007 19.0 4.1 0.0007 19.0 2.8 1.7 2 0 0 2 2 2 1 Mitochondrial fission regulator DUF2051 PF09738.4 EPS30870.1 - 0.04 13.1 2.6 0.11 11.8 1.8 1.7 1 0 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) Selenoprotein_S PF06936.6 EPS30870.1 - 8.1 5.9 10.8 0.2 11.1 2.1 2.2 2 1 1 3 3 3 0 Selenoprotein S (SelS) Het-C PF07217.6 EPS30872.1 - 2.4e-268 891.3 0.0 3.4e-268 890.8 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C FAD_binding_4 PF01565.18 EPS30873.1 - 3.7e-39 133.3 0.0 7.8e-39 132.3 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.14 EPS30873.1 - 9e-34 116.8 0.1 1.6e-33 116.1 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain DUF1204 PF06721.6 EPS30873.1 - 0.13 11.4 0.6 0.24 10.6 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) ADH_N PF08240.7 EPS30874.1 - 6.6e-35 119.1 0.5 6.6e-35 119.1 0.3 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPS30874.1 - 1.2e-19 70.1 0.3 2.2e-19 69.3 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 EPS30874.1 - 0.00016 21.1 0.0 0.00025 20.4 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ADH_zinc_N_2 PF13602.1 EPS30874.1 - 0.006 17.4 0.1 0.012 16.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EPS30874.1 - 0.022 15.3 0.0 0.042 14.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain AlaDh_PNT_C PF01262.16 EPS30874.1 - 0.024 14.1 0.3 0.061 12.8 0.2 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 EPS30874.1 - 0.028 12.8 0.2 0.04 12.3 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein 2-Hacid_dh_C PF02826.14 EPS30874.1 - 0.048 12.8 0.0 0.081 12.0 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EPS30874.1 - 0.067 13.5 0.3 2.1 8.8 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EPS30874.1 - 0.069 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain XdhC_C PF13478.1 EPS30874.1 - 0.095 13.0 0.1 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain DUF1735 PF08522.5 EPS30874.1 - 0.13 12.6 0.0 0.55 10.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1735) Ras PF00071.17 EPS30875.1 - 2.9e-39 134.0 0.0 4.1e-39 133.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPS30875.1 - 5e-13 49.6 0.0 7.8e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPS30875.1 - 6.3e-11 41.8 0.0 7.8e-10 38.2 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EPS30875.1 - 0.00068 18.8 0.0 0.00092 18.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_33 PF13671.1 EPS30875.1 - 0.0073 16.1 0.1 0.016 15.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EPS30875.1 - 0.013 15.3 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.4 EPS30875.1 - 0.047 13.1 0.0 2.2 7.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 EPS30875.1 - 0.05 13.5 0.0 0.083 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EPS30875.1 - 0.06 12.5 0.0 0.096 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EPS30875.1 - 0.07 13.2 0.0 0.12 12.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EPS30875.1 - 0.085 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter SRPRB PF09439.5 EPS30875.1 - 0.2 10.8 0.0 0.34 10.0 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF1183 PF06682.7 EPS30876.1 - 6.3 6.3 15.6 7.8 5.9 10.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) M_domain PF12938.2 EPS30877.1 - 9.9 5.8 8.5 18 5.0 5.9 1.4 1 1 0 1 1 1 0 M domain of GW182 APG6 PF04111.7 EPS30879.1 - 0.35 9.8 2.8 0.59 9.1 2.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 TMCO5 PF14992.1 EPS30879.1 - 1.2 8.2 4.0 1.9 7.5 2.8 1.2 1 0 0 1 1 1 0 TMCO5 family V_ATPase_I PF01496.14 EPS30879.1 - 2.2 6.0 1.8 3.2 5.5 1.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Glyco_tranf_2_3 PF13641.1 EPS30883.1 - 1.1e-26 94.0 0.1 1.6e-26 93.5 0.1 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EPS30883.1 - 2.3e-08 33.9 0.0 4e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EPS30883.1 - 2.6e-06 26.8 0.0 1.6e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 21 ATP12 PF07542.6 EPS30884.1 - 9.2e-36 122.4 0.1 1.7e-35 121.6 0.1 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein Oxysterol_BP PF01237.13 EPS30885.1 - 1.8e-130 434.5 0.0 8e-130 432.4 0.0 1.9 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.2 EPS30885.1 - 4.9e-19 68.4 0.1 1.3e-11 44.7 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EPS30885.1 - 6.2e-17 60.4 0.2 1.6e-05 24.4 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 EPS30885.1 - 2.1e-14 53.2 4.0 4.3e-09 36.3 0.2 4.1 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPS30885.1 - 1e-13 50.0 0.2 0.00085 19.3 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 EPS30885.1 - 1.5e-13 50.8 0.3 7.3e-07 29.5 0.0 4.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) PH PF00169.24 EPS30885.1 - 9.5e-11 41.8 0.2 2.5e-10 40.4 0.2 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EPS30885.1 - 8.7e-09 35.6 1.1 2.4e-08 34.1 0.7 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 EPS30885.1 - 2.4e-06 27.5 0.8 6.5e-06 26.1 0.5 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain zf-Mss51 PF13824.1 EPS30886.1 - 8.3e-29 99.2 6.2 1.9e-28 98.0 4.3 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 EPS30886.1 - 0.017 14.9 0.6 0.017 14.9 0.4 2.1 2 0 0 2 2 2 0 MYND finger DUF1343 PF07075.6 EPS30886.1 - 0.045 12.5 0.0 0.066 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1343) zf-HIT PF04438.11 EPS30886.1 - 0.1 12.2 2.2 1.6 8.3 0.2 2.5 2 0 0 2 2 2 0 HIT zinc finger ADH_zinc_N PF00107.21 EPS30887.1 - 3.1e-30 104.3 0.6 5.9e-30 103.4 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPS30887.1 - 1.1e-09 39.2 0.1 2.4e-09 38.1 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPS30887.1 - 5.8e-07 29.2 0.0 6.5e-06 25.8 0.0 2.7 3 1 1 4 4 4 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 EPS30887.1 - 0.016 15.2 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain adh_short_C2 PF13561.1 EPS30887.1 - 0.023 14.4 0.1 0.047 13.4 0.1 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase HupF_HypC PF01455.13 EPS30887.1 - 0.11 12.5 0.3 0.6 10.1 0.1 2.2 2 0 0 2 2 2 0 HupF/HypC family Pep_deformylase PF01327.16 EPS30887.1 - 0.17 11.2 0.1 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 Polypeptide deformylase AlaDh_PNT_C PF01262.16 EPS30887.1 - 0.21 11.1 1.6 0.2 11.1 0.2 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Clr5 PF14420.1 EPS30888.1 - 8.5e-14 51.1 1.8 1.6e-13 50.2 1.3 1.5 1 0 0 1 1 1 1 Clr5 domain SCIMP PF15050.1 EPS30888.1 - 0.053 13.4 2.4 0.15 11.9 1.6 1.7 1 0 0 1 1 1 0 SCIMP protein Ndc1_Nup PF09531.5 EPS30888.1 - 4.8 5.4 5.1 5.6 5.2 3.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MEF2_binding PF09047.5 EPS30889.1 - 0.82 9.3 4.3 0.46 10.1 0.8 2.2 2 1 0 2 2 2 0 MEF2 binding HTH_27 PF13463.1 EPS30891.1 - 0.064 13.5 0.0 0.097 13.0 0.0 1.3 1 0 0 1 1 1 0 Winged helix DNA-binding domain SNF2_N PF00176.18 EPS30892.1 - 8.9e-73 244.6 0.3 1.3e-72 244.0 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPS30892.1 - 2.5e-14 52.8 0.0 6.4e-14 51.5 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPS30892.1 - 8.7e-09 35.4 0.0 2.6e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EPS30892.1 - 1.3e-05 24.8 0.0 6.7e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase HSA PF07529.8 EPS30892.1 - 2.5e-05 23.9 5.9 0.00011 21.8 4.1 2.2 1 0 0 1 1 1 1 HSA DEAD_2 PF06733.10 EPS30892.1 - 0.022 14.1 0.3 0.048 13.0 0.0 1.7 2 0 0 2 2 2 0 DEAD_2 HEPPP_synt_1 PF07307.6 EPS30892.1 - 0.078 12.4 0.4 0.15 11.5 0.3 1.4 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 NDUF_B8 PF05821.6 EPS30893.1 - 1.2e-08 34.7 0.0 1.6e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Membr_traf_MHD PF10540.4 EPS30894.1 - 2.2e-30 105.2 0.1 1.4e-29 102.5 0.0 2.5 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 EPS30894.1 - 5e-15 55.1 0.0 1.2e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 C2 domain AIG2_2 PF13772.1 EPS30895.1 - 0.0018 18.3 0.2 0.034 14.2 0.0 2.4 2 1 0 2 2 2 1 AIG2-like family EPL1 PF10513.4 EPS30895.1 - 0.14 12.4 0.0 0.27 11.4 0.0 1.6 2 0 0 2 2 2 0 Enhancer of polycomb-like Pribosyltran PF00156.22 EPS30896.1 - 6e-15 55.0 0.0 7.7e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EPS30896.1 - 0.048 12.8 0.0 0.067 12.3 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Thi4 PF01946.12 EPS30896.1 - 0.055 12.5 0.4 0.083 11.9 0.3 1.2 1 0 0 1 1 1 0 Thi4 family Ribonuc_L-PSP PF01042.16 EPS30898.1 - 8.6e-41 138.4 0.1 9.8e-41 138.3 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Glyco_hydro_47 PF01532.15 EPS30899.1 - 6.7e-131 437.0 0.0 8.5e-131 436.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Death PF00531.17 EPS30900.1 - 0.12 12.1 0.1 0.64 9.8 0.0 1.9 2 0 0 2 2 2 0 Death domain WD40 PF00400.27 EPS30901.1 - 4.2e-58 191.2 7.6 6.9e-09 35.2 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EPS30901.1 - 0.00043 19.1 0.7 0.032 12.9 0.1 3.0 1 1 0 2 2 2 2 Nup133 N terminal like PQQ_2 PF13360.1 EPS30901.1 - 0.034 13.5 0.1 4.4 6.6 0.0 3.0 2 1 1 3 3 3 0 PQQ-like domain TRAPP PF04051.11 EPS30902.1 - 4.2e-38 130.2 0.0 5.1e-38 129.9 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF4250 PF14056.1 EPS30902.1 - 0.032 13.9 0.1 0.032 13.9 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4250) PqqD PF05402.7 EPS30902.1 - 0.056 13.4 0.1 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) LisH PF08513.6 EPS30904.1 - 3.6e-05 23.3 0.2 6.5e-05 22.5 0.1 1.4 1 0 0 1 1 1 1 LisH PEGSRP PF07623.6 EPS30904.1 - 0.077 12.3 2.5 14 5.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1584) OMP_b-brl_2 PF13568.1 EPS30905.1 - 0.037 13.8 0.2 0.047 13.4 0.1 1.1 1 0 0 1 1 1 0 Outer membrane protein beta-barrel domain Porin_3 PF01459.17 EPS30905.1 - 2.8 7.1 6.4 3.3 6.9 4.5 1.1 1 0 0 1 1 1 0 Eukaryotic porin RRM_1 PF00076.17 EPS30908.1 - 3.1e-46 154.8 0.0 8e-17 60.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS30908.1 - 3.9e-28 97.2 0.0 2e-09 37.3 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS30908.1 - 2.5e-22 78.4 0.0 2.6e-08 33.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EPS30908.1 - 9.8e-06 25.3 0.0 9.9e-05 22.1 0.0 2.3 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 EPS30908.1 - 0.00012 21.7 0.1 0.0086 15.8 0.0 3.0 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRP7 PF12923.2 EPS30911.1 - 6.3e-32 110.3 9.8 6.3e-32 110.3 6.8 1.5 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) Dak1_2 PF13684.1 EPS30911.1 - 0.028 13.3 0.8 0.065 12.1 0.2 1.7 2 0 0 2 2 2 0 Dihydroxyacetone kinase family Rad51 PF08423.6 EPS30912.1 - 3.4e-125 416.1 0.0 4.7e-125 415.6 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EPS30912.1 - 1.1e-10 41.1 0.0 1.7e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 EPS30912.1 - 2.8e-09 36.5 0.0 3.6e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 EPS30912.1 - 2.7e-08 33.2 0.0 6.1e-08 32.0 0.0 1.6 2 0 0 2 2 2 1 KaiC HHH_5 PF14520.1 EPS30912.1 - 2.7e-08 33.8 2.5 3.4e-08 33.5 0.2 2.2 3 0 0 3 3 3 1 Helix-hairpin-helix domain RNA_pol_A_CTD PF03118.10 EPS30912.1 - 0.057 12.8 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial RNA polymerase, alpha chain C terminal domain zf-CCHC PF00098.18 EPS30913.1 - 4.3e-45 149.5 54.7 8.2e-08 31.8 1.9 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_3 PF13917.1 EPS30913.1 - 2.4e-08 33.5 38.5 0.032 13.9 0.1 6.9 4 2 2 6 6 6 5 Zinc knuckle zf-CCHC_4 PF14392.1 EPS30913.1 - 3.3e-08 33.0 39.4 0.073 12.7 0.4 7.1 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_2 PF13696.1 EPS30913.1 - 0.09 12.2 0.2 0.09 12.2 0.2 7.2 4 2 3 7 7 7 0 Zinc knuckle UDPGP PF01704.13 EPS30914.1 - 1e-57 195.5 0.0 1.5e-57 195.0 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 EPS30914.1 - 0.073 13.1 0.1 0.26 11.3 0.0 1.9 2 0 0 2 2 2 0 MobA-like NTP transferase domain Pro_isomerase PF00160.16 EPS30915.1 - 7.9e-35 120.3 0.0 1.2e-34 119.7 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 EPS30915.1 - 9.6e-16 57.1 0.0 2.2e-15 56.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS30915.1 - 4.6e-12 45.7 0.0 1e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS30915.1 - 1e-09 38.1 0.0 2.2e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPS30915.1 - 0.17 11.6 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Zn_clus PF00172.13 EPS30917.1 - 1.3e-08 34.5 6.8 2.5e-08 33.6 4.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RAP1 PF07218.6 EPS30917.1 - 8.6 4.3 5.0 14 3.5 3.5 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ribosomal_S24e PF01282.14 EPS30918.1 - 6.8e-36 121.9 0.1 1e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S24e FAD_binding_4 PF01565.18 EPS30918.1 - 0.041 13.3 0.0 0.053 12.9 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain Methyltransf_16 PF10294.4 EPS30919.1 - 1.2e-17 63.9 0.0 1.9e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EPS30919.1 - 0.0002 21.8 0.0 0.00039 20.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EPS30919.1 - 0.00047 19.7 0.0 0.00083 19.0 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.9 EPS30919.1 - 0.0015 17.9 0.0 0.0027 17.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EPS30919.1 - 0.013 14.6 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 EPS30919.1 - 0.013 15.0 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 EPS30919.1 - 0.041 13.8 0.0 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain DUF938 PF06080.7 EPS30919.1 - 0.042 13.3 0.0 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_31 PF13847.1 EPS30919.1 - 0.047 13.2 0.0 0.099 12.2 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EPS30919.1 - 0.07 12.8 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF869 PF05911.6 EPS30920.1 - 0.0009 17.6 21.0 0.0009 17.6 14.5 2.0 1 1 1 2 2 2 1 Plant protein of unknown function (DUF869) DivIVA PF05103.8 EPS30920.1 - 0.42 10.6 26.2 4.2 7.4 0.2 3.3 2 1 1 3 3 3 0 DivIVA protein DUF972 PF06156.8 EPS30920.1 - 2.5 8.5 21.6 3.3 8.0 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF972) APG6 PF04111.7 EPS30920.1 - 6.6 5.6 29.5 0.037 13.0 7.1 2.7 1 1 2 3 3 3 0 Autophagy protein Apg6 CLTH PF10607.4 EPS30922.1 - 2.5e-35 121.2 0.0 4.1e-35 120.6 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 EPS30922.1 - 1.9e-22 79.6 0.2 2.8e-22 79.0 0.1 1.3 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 EPS30922.1 - 0.0093 15.7 0.5 0.026 14.2 0.0 2.1 2 0 0 2 2 2 1 LisH INO80_Ies4 PF08193.6 EPS30923.1 - 7.5e-58 196.1 18.0 9.1e-58 195.8 12.5 1.1 1 0 0 1 1 1 1 INO80 complex subunit Ies4 Corona_NS1 PF06145.6 EPS30924.1 - 0.2 10.9 1.3 1.3 8.3 0.7 2.1 2 0 0 2 2 2 0 Coronavirus nonstructural protein NS1 DnaJ PF00226.26 EPS30925.1 - 8.4e-17 60.6 0.0 1.5e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain SHS2_Rpb7-N PF03876.12 EPS30926.1 - 9.9e-06 25.5 0.0 2.3e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 U79_P34 PF03064.11 EPS30926.1 - 3 7.3 14.9 1.2 8.6 4.7 2.3 2 0 0 2 2 2 0 HSV U79 / HCMV P34 GAGA_bind PF06217.7 EPS30926.1 - 3 7.7 15.5 0.37 10.7 5.4 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family RNA_polI_A34 PF08208.6 EPS30926.1 - 5.4 6.6 43.0 0.87 9.2 19.9 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 Pyr_redox_2 PF07992.9 EPS30927.1 - 1.1e-28 100.5 0.3 1.7e-28 99.9 0.2 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 EPS30927.1 - 4.7e-15 54.9 0.1 1.1e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox PF00070.22 EPS30927.1 - 1.9e-14 53.8 3.5 9.5e-13 48.3 0.2 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.1 EPS30927.1 - 1.3e-07 31.8 0.0 7.5e-07 29.3 0.0 2.2 2 0 0 2 2 2 1 Reductase C-terminal Pyr_redox_3 PF13738.1 EPS30927.1 - 2.3e-07 31.0 0.1 4.1e-05 23.7 0.0 3.0 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPS30927.1 - 3.6e-05 23.5 0.5 0.25 11.1 0.0 3.3 3 0 0 3 3 3 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 EPS30927.1 - 0.00013 21.0 0.1 0.1 11.4 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Rieske_2 PF13806.1 EPS30927.1 - 0.00025 20.7 0.0 0.0007 19.2 0.0 1.8 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain DUF1188 PF06690.6 EPS30927.1 - 0.0011 18.1 0.0 0.002 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1188) TrkA_N PF02254.13 EPS30927.1 - 0.0035 17.3 1.1 1.9 8.5 0.1 3.0 3 0 0 3 3 3 2 TrkA-N domain Fungal_trans PF04082.13 EPS30930.1 - 2.5e-23 82.3 0.4 3.9e-23 81.6 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_3 PF07859.8 EPS30931.1 - 3.3e-16 59.5 0.0 2.1e-09 37.3 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EPS30931.1 - 9e-12 44.6 0.0 3e-06 26.5 0.0 2.5 2 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EPS30931.1 - 5.5e-11 42.3 0.0 1.1e-10 41.3 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPS30931.1 - 1.2e-09 38.4 0.0 1.7e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EPS30931.1 - 9.2e-08 31.2 0.4 2.8e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S15 PF02129.13 EPS30931.1 - 2.4e-07 30.4 0.0 1.1e-06 28.2 0.0 2.1 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.15 EPS30931.1 - 3.7e-06 26.5 0.0 0.03 13.7 0.0 2.2 2 0 0 2 2 2 2 Putative esterase Abhydrolase_2 PF02230.11 EPS30931.1 - 8.4e-06 25.3 0.0 0.11 11.9 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase LIP PF03583.9 EPS30931.1 - 0.00098 18.4 0.0 0.04 13.1 0.0 2.3 2 0 0 2 2 2 1 Secretory lipase AXE1 PF05448.7 EPS30931.1 - 0.0051 15.3 0.0 0.14 10.6 0.0 2.1 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) DUF2424 PF10340.4 EPS30931.1 - 0.0089 14.7 0.0 0.019 13.6 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) DLH PF01738.13 EPS30931.1 - 0.018 14.3 0.0 4.8 6.4 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family IDO PF01231.13 EPS30932.1 - 2.5e-33 115.1 0.1 3.2e-32 111.4 0.0 2.1 2 0 0 2 2 2 1 Indoleamine 2,3-dioxygenase Cyt-b5 PF00173.23 EPS30932.1 - 8.9e-14 51.0 0.0 2.1e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Helicase_Sgs1 PF11408.3 EPS30932.1 - 0.082 12.7 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 Sgs1 RecQ helicase p450 PF00067.17 EPS30933.1 - 2.2e-71 240.7 0.0 2.5e-71 240.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Trp_DMAT PF11991.3 EPS30935.1 - 1.4e-13 50.7 0.3 6.8e-13 48.5 0.2 2.1 1 1 0 1 1 1 1 Tryptophan dimethylallyltransferase Glyco_hydro_18 PF00704.23 EPS30936.1 - 1.8e-08 34.2 0.0 1.9e-08 34.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LEAP-2 PF07359.6 EPS30937.1 - 0.19 11.4 0.9 0.7 9.5 0.2 2.1 2 1 1 3 3 3 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) Nucleopor_Nup85 PF07575.8 EPS30939.1 - 4.2e-28 97.8 0.1 3.3e-15 55.3 0.0 4.0 4 0 0 4 4 4 4 Nup85 Nucleoporin Fungal_trans_2 PF11951.3 EPS30942.1 - 1.9e-10 39.9 0.3 2.5e-10 39.5 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS30942.1 - 3.4e-09 36.4 10.2 6.1e-09 35.6 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.7 EPS30943.1 - 2.3e-22 78.8 1.1 3.8e-22 78.1 0.8 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPS30943.1 - 1.9e-18 66.2 0.0 2.8e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPS30943.1 - 7e-08 33.4 0.0 1.2e-07 32.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EPS30943.1 - 0.00085 18.5 0.2 0.0015 17.7 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EPS30943.1 - 0.023 14.7 0.0 0.037 14.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NMO PF03060.10 EPS30943.1 - 0.075 12.1 0.1 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase adh_short PF00106.20 EPS30943.1 - 0.12 12.2 0.4 0.25 11.2 0.3 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Phage_int_SAM_1 PF02899.12 EPS30944.1 - 0.022 14.8 0.1 0.048 13.8 0.0 1.6 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain DUF642 PF04862.7 EPS30945.1 - 0.12 12.0 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF642) DnaJ PF00226.26 EPS30946.1 - 9.8e-08 31.6 2.3 2.1e-07 30.5 1.6 1.5 1 0 0 1 1 1 1 DnaJ domain Ctr PF04145.10 EPS30947.1 - 1e-39 135.9 3.8 1.3e-39 135.5 2.6 1.2 1 0 0 1 1 1 1 Ctr copper transporter family DUF3169 PF11368.3 EPS30947.1 - 0.011 15.0 0.2 0.19 10.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) DUF1673 PF07895.6 EPS30947.1 - 0.11 11.9 2.1 0.12 11.8 0.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1673) GP41 PF00517.12 EPS30947.1 - 0.16 11.4 2.2 0.16 11.5 0.2 1.7 2 0 0 2 2 2 0 Retroviral envelope protein DUF3021 PF11457.3 EPS30947.1 - 0.51 10.2 6.1 0.8 9.5 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) SnoaL_2 PF12680.2 EPS30948.1 - 0.00038 20.8 0.0 0.00052 20.3 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain ADIP PF11559.3 EPS30951.1 - 2.3e-41 141.1 9.2 2.3e-41 141.1 6.4 3.5 5 0 0 5 5 5 1 Afadin- and alpha -actinin-Binding TPR_11 PF13414.1 EPS30952.1 - 7.8e-11 41.4 0.5 5.4e-09 35.5 0.1 2.3 2 0 0 2 2 2 1 TPR repeat LRR_4 PF12799.2 EPS30952.1 - 2.1e-06 27.1 10.0 0.13 11.9 0.2 5.8 3 2 1 4 4 4 2 Leucine Rich repeats (2 copies) TPR_2 PF07719.12 EPS30952.1 - 3.8e-06 26.4 6.1 0.017 14.9 0.5 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat F-box-like PF12937.2 EPS30952.1 - 2.6e-05 23.8 0.1 5.3e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like TPR_12 PF13424.1 EPS30952.1 - 0.00019 21.2 0.1 0.035 14.0 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat F-box PF00646.28 EPS30952.1 - 0.00022 20.7 0.4 0.00071 19.1 0.2 1.9 1 0 0 1 1 1 1 F-box domain TPR_16 PF13432.1 EPS30952.1 - 0.004 17.7 0.1 1.3 9.8 0.0 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat LRR_8 PF13855.1 EPS30952.1 - 0.011 15.5 12.1 2.6 7.8 0.0 5.3 5 1 1 6 6 6 0 Leucine rich repeat TPR_14 PF13428.1 EPS30952.1 - 0.013 16.1 0.3 16 6.4 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EPS30952.1 - 0.044 14.1 0.6 2.4 8.5 0.1 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EPS30952.1 - 0.052 13.1 8.3 0.082 12.5 0.4 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_6 PF13516.1 EPS30952.1 - 0.068 13.2 6.9 12 6.3 0.0 6.0 7 0 0 7 7 7 0 Leucine Rich repeat LRR_7 PF13504.1 EPS30952.1 - 0.073 13.2 9.5 8.7 7.0 0.0 6.2 5 1 0 5 5 5 0 Leucine rich repeat LRR_1 PF00560.28 EPS30952.1 - 2.6 8.4 6.5 19 5.7 0.0 5.2 6 1 0 6 6 3 0 Leucine Rich Repeat IDO PF01231.13 EPS30953.1 - 2.2e-43 148.2 0.0 3.1e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF3824 PF12868.2 EPS30954.1 - 0.046 14.6 0.1 0.052 14.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Pkinase PF00069.20 EPS30954.1 - 0.095 11.8 0.0 0.1 11.6 0.0 1.0 1 0 0 1 1 1 0 Protein kinase domain Sin_N PF04801.8 EPS30954.1 - 0.15 10.8 1.8 0.18 10.6 1.2 1.0 1 0 0 1 1 1 0 Sin-like protein conserved region EF-1_beta_acid PF10587.4 EPS30954.1 - 3.9 7.6 5.5 11 6.2 3.8 1.8 1 1 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region V-ATPase_G PF03179.10 EPS30955.1 - 1.2e-33 115.5 20.5 1.4e-33 115.3 14.2 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.3 EPS30955.1 - 0.18 10.9 23.3 0.04 13.1 8.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) ATP-synt_B PF00430.13 EPS30955.1 - 0.31 10.8 23.2 0.24 11.2 8.4 2.1 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) HypD PF01924.11 EPS30955.1 - 0.33 9.6 2.8 0.38 9.4 1.9 1.1 1 0 0 1 1 1 0 Hydrogenase formation hypA family MMR_HSR1_C PF08438.5 EPS30955.1 - 0.36 11.0 4.5 0.47 10.6 3.1 1.3 1 0 0 1 1 1 0 GTPase of unknown function C-terminal DUF2870 PF11069.3 EPS30955.1 - 0.62 10.1 8.7 1.1 9.3 6.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) DUF2215 PF10225.4 EPS30955.1 - 0.63 9.4 1.9 0.7 9.2 1.3 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) DAG_kinase_N PF14513.1 EPS30955.1 - 0.73 10.0 5.3 0.76 9.9 0.7 2.0 1 1 1 2 2 2 0 Diacylglycerol kinase N-terminus OmpH PF03938.9 EPS30955.1 - 1.5 8.7 19.1 1.9 8.4 13.2 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2201_N PF13203.1 EPS30955.1 - 1.8 7.6 7.9 2 7.5 5.5 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF1525 PF07511.6 EPS30955.1 - 2.4 8.1 6.9 0.99 9.4 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1525) RRF PF01765.14 EPS30955.1 - 2.5 7.5 17.5 0.53 9.7 10.0 1.4 2 0 0 2 2 2 0 Ribosome recycling factor DUF3435 PF11917.3 EPS30955.1 - 3 6.4 9.0 3.4 6.2 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) Toxin_43 PF15604.1 EPS30955.1 - 3.8 7.5 13.0 5.3 7.0 9.0 1.2 1 0 0 1 1 1 0 Putative toxin 43 SAPS PF04499.10 EPS30955.1 - 5.3 5.5 10.4 5.6 5.4 7.2 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein vATP-synt_E PF01991.13 EPS30955.1 - 6.4 5.9 24.9 2.6 7.2 2.3 2.2 1 1 1 2 2 2 0 ATP synthase (E/31 kDa) subunit AIF-MLS PF14962.1 EPS30955.1 - 7.4 6.1 13.0 9.3 5.8 9.0 1.2 1 0 0 1 1 1 0 Mitochondria Localisation Sequence DUF2151 PF10221.4 EPS30955.1 - 8 4.4 10.0 9.1 4.3 6.9 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator Arrestin_N PF00339.24 EPS30957.1 - 9.6e-11 41.7 0.5 8.6e-06 25.6 0.0 2.8 2 1 1 3 3 3 2 Arrestin (or S-antigen), N-terminal domain HNH_2 PF13391.1 EPS30959.1 - 0.0049 16.6 1.3 0.0095 15.6 0.4 1.8 2 0 0 2 2 2 1 HNH endonuclease RNA_pol_Rpb2_6 PF00562.23 EPS30960.1 - 6.2e-124 413.6 0.2 1.9e-123 412.0 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EPS30960.1 - 4.8e-61 205.2 0.0 7.7e-61 204.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EPS30960.1 - 8.3e-47 159.0 0.0 1.6e-46 158.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EPS30960.1 - 5.1e-31 106.7 0.0 1.3e-30 105.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EPS30960.1 - 2.3e-25 88.1 1.0 5.4e-25 86.9 0.7 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EPS30960.1 - 3.6e-23 81.0 0.4 2.2e-22 78.5 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EPS30960.1 - 9.9e-23 79.8 0.4 2.4e-22 78.6 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 CTNNBL PF08216.6 EPS30961.1 - 3.9e-35 119.7 0.8 2.6e-34 117.0 0.3 2.6 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.18 EPS30961.1 - 0.0012 18.5 0.0 0.57 10.1 0.0 3.4 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat Drf_GBD PF06371.8 EPS30961.1 - 0.0084 15.4 0.7 0.061 12.6 0.1 2.6 1 1 0 2 2 2 1 Diaphanous GTPase-binding Domain Mo25 PF08569.6 EPS30961.1 - 0.035 13.1 1.4 0.16 10.9 0.5 2.4 1 1 1 2 2 2 0 Mo25-like ING PF12998.2 EPS30963.1 - 6.2e-23 81.0 5.1 1.1e-22 80.2 3.5 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EPS30963.1 - 3.3e-08 33.1 9.9 5.7e-08 32.3 6.9 1.4 1 0 0 1 1 1 1 PHD-finger Cwf_Cwc_15 PF04889.7 EPS30963.1 - 0.0052 16.5 4.6 0.0093 15.7 3.2 1.4 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein DUF4200 PF13863.1 EPS30963.1 - 0.074 12.9 4.1 1.5 8.7 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) PHD_2 PF13831.1 EPS30963.1 - 0.66 9.3 5.1 1.3 8.3 3.5 1.5 1 0 0 1 1 1 0 PHD-finger TFIIA PF03153.8 EPS30963.1 - 3 7.6 16.5 2.1 8.1 10.5 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NAPRTase PF04095.11 EPS30964.1 - 4.1e-51 173.6 0.3 7.6e-51 172.7 0.2 1.4 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family Fungal_trans PF04082.13 EPS30965.1 - 2.9e-27 95.1 1.9 2.9e-27 95.1 1.3 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain RNA_pol_Rpc34 PF05158.7 EPS30966.1 - 3.6e-115 384.6 0.0 4e-115 384.4 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.7 EPS30966.1 - 0.0097 15.7 0.1 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC TPR_11 PF13414.1 EPS30967.1 - 6.5e-56 185.8 22.6 1.8e-18 65.9 1.0 6.4 4 2 3 7 7 7 7 TPR repeat TPR_1 PF00515.23 EPS30967.1 - 9e-45 148.5 22.9 3.8e-06 26.2 0.0 8.7 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 EPS30967.1 - 4.4e-34 113.6 21.8 0.00041 20.0 0.0 9.5 8 1 1 9 9 9 6 Tetratricopeptide repeat TPR_12 PF13424.1 EPS30967.1 - 7.3e-23 80.2 20.9 4.6e-10 39.2 0.1 5.5 4 2 1 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.1 EPS30967.1 - 2.3e-21 75.8 20.1 3.4e-05 24.4 0.0 6.7 3 1 2 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.1 EPS30967.1 - 9e-16 56.4 20.5 0.00086 18.9 0.0 7.0 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 EPS30967.1 - 1.5e-15 56.3 13.9 0.27 11.9 0.3 9.1 3 3 6 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.1 EPS30967.1 - 1.3e-12 47.8 15.1 0.012 15.9 0.1 6.7 4 2 2 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 EPS30967.1 - 1e-10 40.5 14.0 0.021 14.5 0.0 8.2 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.1 EPS30967.1 - 2e-10 40.0 9.9 0.0025 17.8 0.1 7.5 7 1 0 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 EPS30967.1 - 2.1e-09 37.1 8.0 0.029 14.2 0.1 5.4 3 2 2 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EPS30967.1 - 3.6e-07 30.2 10.2 0.0034 17.5 0.3 4.0 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EPS30967.1 - 6e-06 26.3 17.5 1.5 9.4 0.0 8.3 8 0 0 8 8 8 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EPS30967.1 - 3.1e-05 23.7 2.1 0.19 11.6 0.0 4.9 5 0 0 5 5 5 1 Fis1 C-terminal tetratricopeptide repeat RPN7 PF10602.4 EPS30967.1 - 0.0025 17.2 9.8 0.69 9.2 0.1 5.0 4 1 1 5 5 5 2 26S proteasome subunit RPN7 TPR_10 PF13374.1 EPS30967.1 - 0.0048 16.7 7.5 0.66 9.9 0.1 5.4 6 0 0 6 6 5 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 EPS30967.1 - 0.0059 15.8 4.4 8.6 5.7 0.0 4.5 4 0 0 4 4 4 0 SHNi-TPR TPR_20 PF14561.1 EPS30967.1 - 0.0074 16.3 0.1 0.0074 16.3 0.1 5.0 5 1 1 6 6 6 1 Tetratricopeptide repeat NARP1 PF12569.3 EPS30967.1 - 0.031 13.0 0.2 0.031 13.0 0.1 3.7 4 0 0 4 4 4 0 NMDA receptor-regulated protein 1 DUF2937 PF11157.3 EPS30967.1 - 0.26 10.5 4.2 0.39 10.0 2.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Alkyl_sulf_dimr PF14863.1 EPS30967.1 - 1.6 8.9 11.6 0.47 10.6 0.1 4.0 3 3 0 4 4 4 0 Alkyl sulfatase dimerisation MIT PF04212.13 EPS30967.1 - 2.3 8.1 24.4 14 5.6 0.0 6.7 5 1 2 7 7 7 0 MIT (microtubule interacting and transport) domain C2 PF00168.25 EPS30968.1 - 3.1e-70 232.0 1.9 8.9e-23 79.9 0.0 5.5 5 0 0 5 5 5 5 C2 domain DUF2404 PF10296.4 EPS30968.1 - 0.034 14.2 0.1 0.5 10.5 0.0 2.7 2 0 0 2 2 2 0 Putative integral membrane protein conserved region (DUF2404) Glycos_transf_1 PF00534.15 EPS30968.1 - 0.065 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 B56 PF01603.15 EPS30968.1 - 0.38 9.2 0.0 0.61 8.6 0.0 1.2 1 0 0 1 1 1 0 Protein phosphatase 2A regulatory B subunit (B56 family) UDPGP PF01704.13 EPS30970.1 - 2.3e-184 612.8 0.3 2.6e-184 612.6 0.2 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase PilO PF04350.8 EPS30970.1 - 0.0044 16.9 0.1 0.013 15.3 0.0 1.8 2 0 0 2 2 2 1 Pilus assembly protein, PilO Fungal_trans PF04082.13 EPS30971.1 - 4.1e-20 71.7 2.1 4.1e-20 71.7 1.4 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS30971.1 - 9.9e-07 28.5 9.2 1.7e-06 27.7 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EPS30972.1 - 8.5e-16 57.5 2.5 8.5e-16 57.5 1.7 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS30972.1 - 1.5e-08 34.4 11.2 1.5e-08 34.4 7.7 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.14 EPS30973.1 - 1e-06 27.7 24.2 0.032 13.8 2.0 4.1 3 0 0 3 3 3 3 AT hook motif Glycoprotein_B PF00606.13 EPS30975.1 - 1.2 7.0 5.3 1.5 6.7 3.7 1.1 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B MFS_1 PF07690.11 EPS30976.1 - 9.4e-22 77.1 36.8 3.3e-16 58.9 13.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS30976.1 - 2.6e-17 62.5 19.7 5.6e-17 61.4 13.2 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter Glyco_hydro_28 PF00295.12 EPS30977.1 - 1.3e-31 109.7 5.0 1.7e-31 109.4 3.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.2 EPS30977.1 - 1.5e-07 31.7 11.3 6.1e-07 29.7 7.2 2.3 1 1 1 2 2 2 1 Pectate lyase superfamily protein Ribosomal_L7Ae PF01248.21 EPS30978.1 - 1.9e-27 94.5 0.0 2.3e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EPS30978.1 - 6.2e-06 26.1 0.1 6.6e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 EPS30978.1 - 0.0013 18.4 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain Metallophos_2 PF12850.2 EPS30979.1 - 5.6e-06 26.2 0.0 6.2e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EPS30979.1 - 3.3e-05 23.3 0.1 9.1e-05 21.9 0.1 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase HNH_2 PF13391.1 EPS30980.1 - 7.5e-10 38.4 0.0 1.2e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease Glyoxalase_2 PF12681.2 EPS30981.1 - 2.8e-11 44.0 0.0 3.6e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EPS30981.1 - 5.7e-10 39.2 0.0 1.2e-09 38.2 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EPS30981.1 - 0.0026 17.7 0.0 0.0035 17.3 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EPS30981.1 - 0.019 14.8 0.1 0.083 12.7 0.1 1.9 1 1 0 1 1 1 0 Glyoxalase-like domain BTB PF00651.26 EPS30982.1 - 0.01 15.7 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain Dyp_perox PF04261.7 EPS30982.1 - 0.04 12.6 0.0 0.061 12.0 0.0 1.2 1 0 0 1 1 1 0 Dyp-type peroxidase family MFS_1 PF07690.11 EPS30983.1 - 1.3e-31 109.6 30.4 1.3e-31 109.6 21.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PSDC PF12588.3 EPS30984.1 - 6.4e-51 171.6 0.0 9.3e-51 171.1 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 EPS30984.1 - 6.8e-36 123.4 0.0 2.2e-35 121.8 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylserine decarboxylase Biotin_lipoyl_2 PF13533.1 EPS30984.1 - 0.16 11.6 0.3 16 5.2 0.0 2.4 2 0 0 2 2 2 0 Biotin-lipoyl like Ank_2 PF12796.2 EPS30985.1 - 1.2e-39 134.4 0.0 2.6e-18 66.1 0.0 3.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EPS30985.1 - 4e-22 76.8 0.3 0.00089 18.9 0.0 6.7 5 1 1 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 EPS30985.1 - 1e-17 64.1 0.3 0.0011 19.4 0.0 5.8 6 0 0 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPS30985.1 - 7.8e-16 56.6 3.6 0.0053 16.8 0.0 7.4 6 1 1 7 7 7 4 Ankyrin repeat Ank_5 PF13857.1 EPS30985.1 - 5.7e-12 45.4 5.0 0.025 14.8 0.0 6.1 4 3 3 7 7 7 3 Ankyrin repeats (many copies) DiS_P_DiS PF06750.8 EPS30985.1 - 0.011 15.4 0.0 1.8 8.3 0.0 2.4 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain DAZAP2 PF11029.3 EPS30985.1 - 0.15 12.5 0.5 0.34 11.3 0.4 1.5 1 0 0 1 1 1 0 DAZ associated protein 2 (DAZAP2) S1-P1_nuclease PF02265.11 EPS30987.1 - 3.3e-71 239.8 0.0 3.8e-71 239.6 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease UBA_4 PF14555.1 EPS30988.1 - 0.027 14.0 2.8 0.093 12.2 0.2 2.4 2 0 0 2 2 2 0 UBA-like domain VWA_2 PF13519.1 EPS30988.1 - 0.09 12.8 0.0 0.35 10.9 0.0 2.2 2 1 0 2 2 2 0 von Willebrand factor type A domain FAD_binding_3 PF01494.14 EPS30989.1 - 2.6e-29 102.3 0.1 7.3e-29 100.9 0.1 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EPS30989.1 - 0.00013 21.8 0.2 0.00036 20.4 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EPS30989.1 - 0.0012 17.7 3.4 0.027 13.3 0.1 2.5 3 0 0 3 3 3 2 Lycopene cyclase protein DAO PF01266.19 EPS30989.1 - 0.034 13.0 1.1 0.071 12.0 0.5 1.8 1 1 1 2 2 2 0 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 EPS30989.1 - 0.094 12.4 0.1 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Metallophos PF00149.23 EPS30992.1 - 5e-09 35.8 0.4 1.2e-08 34.5 0.3 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EPS30992.1 - 8.4e-06 25.7 0.1 1.8e-05 24.6 0.1 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain BTB PF00651.26 EPS30993.1 - 6.7e-06 26.0 0.0 1.3e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Orthoreo_P10 PF07204.6 EPS30995.1 - 0.008 15.9 11.1 0.47 10.2 0.2 5.0 4 1 0 4 4 4 3 Orthoreovirus membrane fusion protein p10 Acetyltransf_2 PF00797.12 EPS30997.1 - 3.2e-43 148.0 0.3 4.2e-42 144.3 0.2 2.1 1 1 0 1 1 1 1 N-acetyltransferase Transglut_core PF01841.14 EPS30997.1 - 3.1e-05 24.1 0.1 6.7e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily FAD_binding_3 PF01494.14 EPS30998.1 - 2.6e-21 76.0 1.1 2.9e-20 72.6 0.8 2.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EPS30998.1 - 9.1e-06 24.8 2.3 0.073 11.9 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EPS30998.1 - 0.00013 21.1 0.3 0.043 12.8 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EPS30998.1 - 0.00089 19.2 0.4 0.0027 17.6 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 EPS30998.1 - 0.019 13.8 0.0 0.023 13.5 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase FAD_binding_2 PF00890.19 EPS30998.1 - 0.029 13.2 0.6 0.046 12.5 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 EPS30998.1 - 0.096 12.7 0.3 0.47 10.4 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EPS30998.1 - 0.27 9.6 2.8 0.67 8.3 0.8 2.0 2 0 0 2 2 2 0 HI0933-like protein Acetyltransf_7 PF13508.1 EPS30999.1 - 4.5e-08 33.1 0.0 6.6e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPS30999.1 - 4.8e-07 29.7 0.0 7.6e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EPS30999.1 - 1.6e-05 24.9 0.0 2.1e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EPS30999.1 - 0.0022 17.9 0.0 0.0026 17.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NAD_binding_10 PF13460.1 EPS31000.1 - 2.5e-11 43.9 0.0 3.3e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EPS31000.1 - 3.1e-06 26.6 0.0 2.9e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.16 EPS31000.1 - 0.00045 19.7 0.0 0.0037 16.7 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EPS31000.1 - 0.021 14.7 0.0 0.14 12.0 0.0 1.9 1 1 1 2 2 2 0 short chain dehydrogenase Peripla_BP_6 PF13458.1 EPS31000.1 - 0.095 12.0 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein APH PF01636.18 EPS31004.1 - 4.2e-11 43.0 0.0 7.9e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPS31004.1 - 2.7e-07 30.3 0.0 4.7e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase UPF0233 PF06781.7 EPS31005.1 - 0.03 13.9 0.1 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) DUF4014 PF13198.1 EPS31005.1 - 0.036 14.4 0.3 0.067 13.6 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4014) TarH PF02203.10 EPS31005.1 - 0.048 13.5 0.2 0.083 12.7 0.1 1.4 2 0 0 2 2 2 0 Tar ligand binding domain homologue DUF3040 PF11239.3 EPS31005.1 - 0.066 13.2 0.0 0.094 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF2370 PF10176.4 EPS31005.1 - 0.1 11.9 0.1 0.095 12.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Herpes_US9 PF06072.6 EPS31005.1 - 0.11 12.3 0.4 0.17 11.7 0.2 1.2 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 HAMP PF00672.20 EPS31005.1 - 0.39 10.9 1.6 0.56 10.4 1.1 1.3 1 0 0 1 1 1 0 HAMP domain Amidase PF01425.16 EPS31006.1 - 8.9e-83 278.5 0.0 1.5e-82 277.8 0.0 1.3 1 1 0 1 1 1 1 Amidase MFS_1 PF07690.11 EPS31007.1 - 2.4e-11 42.9 21.3 2.4e-11 42.9 14.8 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF788 PF05620.6 EPS31007.1 - 0.36 10.6 1.1 3.7 7.3 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF788) Fungal_trans_2 PF11951.3 EPS31008.1 - 1.2e-09 37.2 1.9 7.7e-08 31.3 0.2 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS31008.1 - 1.7e-06 27.8 8.5 3.2e-06 26.9 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 EPS31009.1 - 1.1e-07 31.6 11.4 2e-07 30.8 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EPS31009.1 - 0.00031 19.6 0.1 0.00064 18.6 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain FYVE PF01363.16 EPS31010.1 - 4.1e-21 74.6 1.0 4.1e-21 74.6 0.7 3.1 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.1 EPS31010.1 - 3.4e-09 36.3 4.5 3.4e-09 36.3 3.1 3.4 3 0 0 3 3 3 1 Ring finger domain Rad50_zn_hook PF04423.9 EPS31010.1 - 0.00064 19.1 0.4 0.17 11.4 0.0 2.4 2 0 0 2 2 2 2 Rad50 zinc hook motif zf-C3HC4 PF00097.20 EPS31010.1 - 0.0022 17.6 3.7 0.0022 17.6 2.5 3.5 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPS31010.1 - 0.0025 17.7 4.4 0.0025 17.7 3.1 3.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EPS31010.1 - 0.0038 17.3 2.3 0.0038 17.3 1.6 3.1 3 1 0 3 3 3 1 RING-H2 zinc finger FYVE_2 PF02318.11 EPS31010.1 - 0.022 14.6 0.4 0.022 14.6 0.3 2.2 3 0 0 3 3 3 0 FYVE-type zinc finger Lar_restr_allev PF14354.1 EPS31010.1 - 0.13 12.6 5.6 0.54 10.6 2.1 2.5 2 0 0 2 2 2 0 Restriction alleviation protein Lar RINGv PF12906.2 EPS31010.1 - 0.46 10.5 8.5 0.24 11.4 3.0 2.5 2 0 0 2 2 2 0 RING-variant domain FANCL_C PF11793.3 EPS31010.1 - 6.7 6.7 13.3 0.035 14.0 2.5 2.1 2 0 0 2 2 2 0 FANCL C-terminal domain TRP PF06011.7 EPS31011.1 - 5.6e-85 285.5 24.6 3.2e-84 283.0 17.0 1.9 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EPS31011.1 - 2.2e-25 89.3 0.2 3.2e-25 88.8 0.2 1.2 1 0 0 1 1 1 1 ML-like domain Cys_Met_Meta_PP PF01053.15 EPS31014.1 - 2.6e-61 207.0 0.0 5.6e-61 205.9 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EPS31014.1 - 2e-05 23.7 0.0 3.3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EPS31014.1 - 0.0025 16.6 0.0 0.005 15.6 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EPS31014.1 - 0.0064 15.5 0.0 3.1 6.7 0.0 3.0 3 0 0 3 3 3 2 DegT/DnrJ/EryC1/StrS aminotransferase family MFS_1 PF07690.11 EPS31015.1 - 7.3e-37 126.8 28.8 7.3e-37 126.8 20.0 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily ThiS PF02597.15 EPS31016.1 - 5.7e-08 33.0 0.0 6.5e-08 32.8 0.0 1.0 1 0 0 1 1 1 1 ThiS family MARVEL PF01284.18 EPS31017.1 - 0.016 14.9 11.8 0.024 14.4 8.1 1.3 1 0 0 1 1 1 0 Membrane-associating domain DUF2301 PF10063.4 EPS31017.1 - 0.15 12.2 3.9 0.24 11.6 2.7 1.4 1 0 0 1 1 1 0 Uncharacterized integral membrane protein (DUF2301) FAD_binding_4 PF01565.18 EPS31019.1 - 2.7e-20 72.2 1.2 4.5e-20 71.5 0.8 1.4 1 0 0 1 1 1 1 FAD binding domain RNB PF00773.14 EPS31020.1 - 2.4e-51 174.9 0.0 2.1e-50 171.8 0.0 2.4 1 1 0 1 1 1 1 RNB domain AMP-binding PF00501.23 EPS31021.1 - 2.6e-67 227.0 0.0 3.6e-67 226.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPS31021.1 - 1.2e-12 48.5 0.0 3.2e-12 47.2 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain BolA PF01722.13 EPS31022.1 - 1.4e-29 101.8 2.8 1.8e-29 101.5 1.9 1.1 1 0 0 1 1 1 1 BolA-like protein RPA_C PF08784.6 EPS31022.1 - 0.088 13.2 0.1 0.17 12.2 0.1 1.5 1 1 0 1 1 1 0 Replication protein A C terminal SNARE PF05739.14 EPS31023.1 - 3e-11 42.8 2.6 3e-11 42.8 1.8 2.5 2 0 0 2 2 2 1 SNARE domain DUF3153 PF11353.3 EPS31023.1 - 0.008 15.6 0.4 0.018 14.5 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3153) Dispanin PF04505.7 EPS31023.1 - 0.017 14.6 0.5 0.039 13.4 0.3 1.6 1 0 0 1 1 1 0 Interferon-induced transmembrane protein Bac_export_3 PF01313.14 EPS31023.1 - 0.05 13.2 0.3 0.05 13.2 0.2 2.7 3 0 0 3 3 3 0 Bacterial export proteins, family 3 Axin_b-cat_bind PF08833.5 EPS31023.1 - 0.069 12.8 0.0 0.4 10.4 0.0 2.1 2 0 0 2 2 2 0 Axin beta-catenin binding domain Halo_GVPC PF05465.8 EPS31023.1 - 0.088 12.7 0.1 6.6 6.7 0.0 3.1 3 0 0 3 3 3 0 Halobacterial gas vesicle protein C (GVPC) repeat GP41 PF00517.12 EPS31023.1 - 0.23 10.9 4.8 0.068 12.7 0.3 2.3 2 1 0 2 2 2 0 Retroviral envelope protein HisKA_3 PF07730.8 EPS31023.1 - 1.2 9.5 7.3 4.8 7.6 0.3 3.1 2 1 0 2 2 2 0 Histidine kinase COG5 PF10392.4 EPS31023.1 - 1.3 8.9 11.0 0.2 11.6 1.7 3.0 3 1 0 3 3 3 0 Golgi transport complex subunit 5 DUF3619 PF12279.3 EPS31023.1 - 4.3 7.4 11.2 6.5 6.8 0.7 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3619) Fib_alpha PF08702.5 EPS31023.1 - 7.9 6.5 15.2 0.88 9.6 0.7 2.7 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family V-SNARE PF05008.10 EPS31023.1 - 8.1 6.6 17.5 3.9 7.6 0.1 4.8 4 2 1 5 5 5 0 Vesicle transport v-SNARE protein N-terminus PTR2 PF00854.16 EPS31024.1 - 4.2e-53 180.4 9.3 2.5e-50 171.3 6.4 2.3 1 1 0 1 1 1 1 POT family p450 PF00067.17 EPS31026.1 - 4.4e-41 140.8 0.0 5.6e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1707 PF08044.6 EPS31026.1 - 0.0073 16.0 0.1 0.014 15.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1707) Vps23_core PF09454.5 EPS31026.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Vps23 core domain IF4E PF01652.13 EPS31027.1 - 1.4e-59 200.2 0.0 1.7e-59 200.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Mpv17_PMP22 PF04117.7 EPS31028.1 - 7.9e-26 89.4 1.3 1.4e-25 88.7 0.9 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Ribosomal_S5 PF00333.15 EPS31029.1 - 3.6e-27 93.8 2.1 8.9e-27 92.6 1.0 1.9 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EPS31029.1 - 1.9e-21 75.0 0.1 3.9e-21 74.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Bac_rhodopsin PF01036.13 EPS31032.1 - 5.5e-29 101.0 14.1 6.7e-29 100.7 9.8 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein tRNA-synt_1 PF00133.17 EPS31033.1 - 5.8e-168 559.6 0.0 7.4e-168 559.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EPS31033.1 - 1.6e-21 76.4 0.0 1e-12 47.4 0.0 3.6 3 1 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EPS31033.1 - 8.5e-21 74.3 0.3 1.6e-20 73.3 0.2 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EPS31033.1 - 0.031 13.3 0.0 3 6.9 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.1 EPS31033.1 - 0.033 13.4 0.0 0.059 12.6 0.0 1.3 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 zf-FPG_IleRS PF06827.9 EPS31033.1 - 0.057 13.0 6.3 0.89 9.2 4.9 2.3 1 1 1 2 2 2 0 Zinc finger found in FPG and IleRS UPF0183 PF03676.9 EPS31034.1 - 1.7e-37 128.9 0.0 5.5e-27 94.3 0.0 3.7 3 1 0 3 3 3 3 Uncharacterised protein family (UPF0183) Kinesin PF00225.18 EPS31035.1 - 1.7e-111 372.1 1.9 1.7e-111 372.1 1.3 2.2 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bind PF13931.1 EPS31035.1 - 4.3e-08 33.4 0.0 4.3e-08 33.4 0.0 4.8 4 1 0 5 5 5 1 Kinesin-associated microtubule-binding Filament PF00038.16 EPS31035.1 - 0.017 14.5 54.9 0.4 10.1 15.3 3.6 2 1 1 3 3 3 0 Intermediate filament protein Baculo_PEP_C PF04513.7 EPS31035.1 - 0.045 13.5 26.8 0.065 13.0 0.0 5.9 3 2 2 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus zf-Apc11 PF12861.2 EPS31037.1 - 2.8e-46 155.2 11.1 3.3e-46 155.0 7.7 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EPS31037.1 - 8e-32 109.1 9.9 9.3e-32 108.9 6.9 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EPS31037.1 - 3.6e-08 33.1 17.4 1.9e-07 30.8 11.9 2.4 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EPS31037.1 - 9.9e-06 25.1 12.1 0.00056 19.5 8.5 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPS31037.1 - 0.00013 21.9 14.1 0.0018 18.2 9.8 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPS31037.1 - 0.00066 19.2 13.0 0.0028 17.2 9.0 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EPS31037.1 - 0.00073 19.0 11.6 0.00078 18.9 0.8 2.6 1 1 1 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 EPS31037.1 - 0.0008 19.0 14.3 0.0047 16.6 10.0 2.3 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EPS31037.1 - 0.0014 18.4 1.7 0.0014 18.4 1.2 2.4 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EPS31037.1 - 0.0024 17.7 15.6 0.072 13.0 10.8 3.2 1 1 0 1 1 1 1 FANCL C-terminal domain zf-DBF PF07535.7 EPS31037.1 - 0.008 15.8 1.2 0.44 10.2 0.0 2.3 2 0 0 2 2 2 1 DBF zinc finger zf-RING_3 PF14369.1 EPS31037.1 - 0.042 13.8 4.3 2.3 8.2 0.1 3.2 3 0 0 3 3 3 0 zinc-finger Opy2 PF09463.5 EPS31037.1 - 0.22 11.6 7.5 1 9.5 2.3 2.4 2 1 0 2 2 2 0 Opy2 protein zf-RING-like PF08746.6 EPS31037.1 - 0.33 10.9 11.4 1.8 8.6 7.9 2.2 1 1 0 1 1 1 0 RING-like domain zf-Nse PF11789.3 EPS31037.1 - 0.35 10.4 5.2 0.7 9.4 3.6 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF2256 PF10013.4 EPS31037.1 - 0.41 10.4 0.3 0.41 10.4 0.2 3.3 3 1 1 4 4 3 0 Uncharacterized protein conserved in bacteria (DUF2256) PHD PF00628.24 EPS31037.1 - 0.46 10.2 13.1 2.1 8.1 9.1 2.1 1 1 0 1 1 1 0 PHD-finger DZR PF12773.2 EPS31037.1 - 1 9.1 10.7 4.1 7.3 5.0 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-Di19 PF05605.7 EPS31037.1 - 2.1 8.5 11.6 83 3.4 5.5 3.1 1 1 1 2 2 1 0 Drought induced 19 protein (Di19), zinc-binding RecR PF02132.10 EPS31037.1 - 2.4 7.6 4.9 8.6 5.8 0.1 3.0 3 0 0 3 3 3 0 RecR protein RINGv PF12906.2 EPS31037.1 - 4.3 7.4 13.5 10 6.2 8.4 2.3 1 1 1 2 2 2 0 RING-variant domain zf-RING_UBOX PF13445.1 EPS31037.1 - 6.4 6.5 8.8 7 6.4 4.3 2.4 1 1 1 2 2 2 0 RING-type zinc-finger DUF329 PF03884.9 EPS31037.1 - 7.9 6.1 8.7 2.2 7.9 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF329) zf-HIT PF04438.11 EPS31037.1 - 8.3 6.1 10.6 2.8 7.6 3.5 2.4 2 1 0 2 2 2 0 HIT zinc finger zinc-ribbons_6 PF07191.7 EPS31037.1 - 9.1 6.1 9.3 9.4 6.1 0.1 2.4 1 1 0 2 2 2 0 zinc-ribbons Rhodanese PF00581.15 EPS31038.1 - 2.1e-18 66.7 0.0 1.9e-09 37.8 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain PIN_4 PF13638.1 EPS31039.1 - 0.00014 21.9 0.0 0.036 14.1 0.0 2.4 1 1 0 1 1 1 1 PIN domain API5 PF05918.6 EPS31039.1 - 5.9 5.2 4.8 9.1 4.6 3.4 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) RPEL PF02755.10 EPS31041.1 - 4.4e-28 95.8 11.9 6.9e-10 37.9 0.4 3.5 3 0 0 3 3 3 3 RPEL repeat TnpV PF14198.1 EPS31041.1 - 0.034 14.0 0.4 0.065 13.1 0.1 1.5 1 1 0 1 1 1 0 Transposon-encoded protein TnpV HDAC4_Gln PF12203.3 EPS31041.1 - 0.16 11.9 3.4 0.2 11.6 0.3 2.1 2 0 0 2 2 2 0 Glutamine rich N terminal domain of histone deacetylase 4 Translin PF01997.11 EPS31042.1 - 6.5e-68 228.2 0.3 7.7e-68 228.0 0.2 1.1 1 0 0 1 1 1 1 Translin family ADH_N PF08240.7 EPS31043.1 - 5.9e-24 83.9 0.8 1e-23 83.1 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPS31043.1 - 8.3e-23 80.3 0.0 1.2e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPS31043.1 - 0.00015 22.6 0.0 0.00024 22.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TNFR_c6 PF00020.13 EPS31043.1 - 0.0019 18.2 0.7 0.0045 17.0 0.5 1.6 1 0 0 1 1 1 1 TNFR/NGFR cysteine-rich region Glyco_hydro_2 PF00703.16 EPS31044.1 - 1.7e-13 50.9 0.0 4.2e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 EPS31044.1 - 9.6e-10 38.2 0.1 2.9e-09 36.7 0.1 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EPS31044.1 - 0.00019 20.4 0.0 0.0004 19.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Fungal_trans PF04082.13 EPS31045.1 - 1.1e-21 76.8 0.2 1.9e-21 76.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS31045.1 - 3.3e-06 26.9 14.2 6e-06 26.0 9.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mannosyl_trans PF05007.8 EPS31046.1 - 6e-76 255.5 12.8 7.8e-76 255.1 8.8 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 EPS31046.1 - 9.4e-11 41.1 17.0 2e-10 40.1 11.8 1.5 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 EPS31046.1 - 1.3e-05 24.8 31.0 1.3e-05 24.8 21.5 3.0 2 1 0 3 3 3 1 Protein of unknown function (DUF2029) DUF1158 PF06643.6 EPS31046.1 - 4.5 7.6 10.6 1.1 9.6 3.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1158) FHA PF00498.21 EPS31047.1 - 0.0069 16.4 0.0 0.017 15.2 0.0 1.6 1 0 0 1 1 1 1 FHA domain BRCT PF00533.21 EPS31047.1 - 0.026 14.6 0.0 6.4 7.0 0.0 2.4 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain IMS PF00817.15 EPS31048.1 - 8.3e-43 145.7 0.4 1.6e-42 144.8 0.3 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EPS31048.1 - 1.3e-16 60.7 0.1 4.5e-16 58.9 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EPS31048.1 - 1.3e-05 24.9 0.0 4e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif PhyH PF05721.8 EPS31050.1 - 1.6e-05 25.0 0.4 6.8e-05 22.9 0.3 2.0 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 EPS31050.1 - 7.5e-05 21.3 0.0 0.39 9.1 0.1 3.0 3 0 0 3 3 3 3 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_5 PF13759.1 EPS31050.1 - 0.021 15.0 0.0 0.047 13.9 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase FAD_binding_3 PF01494.14 EPS31051.1 - 2.4e-18 66.3 5.4 1.5e-17 63.6 3.7 2.2 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EPS31051.1 - 1.8e-09 36.9 0.2 4e-06 25.9 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EPS31051.1 - 2.1e-07 29.9 0.2 0.014 14.0 0.1 2.8 3 0 0 3 3 3 2 Tryptophan halogenase Pyr_redox_2 PF07992.9 EPS31051.1 - 2e-06 27.8 1.0 2.3e-05 24.3 0.7 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPS31051.1 - 1.1e-05 25.4 0.1 3e-05 23.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EPS31051.1 - 1.2e-05 24.3 0.2 4e-05 22.6 0.3 1.7 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 EPS31051.1 - 0.00032 19.6 0.0 0.00045 19.2 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EPS31051.1 - 0.00077 19.2 3.1 0.13 12.0 0.1 2.7 3 0 0 3 3 3 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EPS31051.1 - 0.00096 18.1 5.1 0.0026 16.7 1.9 2.7 3 1 0 3 3 3 1 Lycopene cyclase protein Pyr_redox PF00070.22 EPS31051.1 - 0.0015 18.8 0.4 0.0044 17.3 0.3 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EPS31051.1 - 0.0023 16.4 1.3 0.0031 16.0 0.2 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 EPS31051.1 - 0.0076 16.3 0.5 0.045 13.7 0.3 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EPS31051.1 - 0.01 15.3 0.2 0.1 12.1 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain SE PF08491.5 EPS31051.1 - 0.02 13.6 0.0 1.1 8.0 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase FAD_oxidored PF12831.2 EPS31051.1 - 0.074 12.1 0.6 0.15 11.1 0.4 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 EPS31051.1 - 0.083 11.9 0.1 0.22 10.5 0.1 1.6 2 0 0 2 2 2 0 Thi4 family Amino_oxidase PF01593.19 EPS31051.1 - 0.12 11.4 0.7 1.1 8.2 0.1 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase zf-C2H2 PF00096.21 EPS31052.1 - 7.3e-10 38.6 10.3 6.3e-05 23.0 0.1 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type Fungal_trans PF04082.13 EPS31052.1 - 1.2e-09 37.4 1.4 2e-09 36.6 1.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 EPS31052.1 - 3e-08 33.5 6.5 0.00016 21.8 0.3 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EPS31052.1 - 1.7e-07 31.1 18.6 1.8e-05 24.7 0.3 3.7 3 0 0 3 3 2 2 C2H2-type zinc finger zf-met PF12874.2 EPS31052.1 - 0.00036 20.6 2.5 0.1 12.8 0.0 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type Zn_clus PF00172.13 EPS31052.1 - 0.0015 18.3 11.0 0.0039 17.0 7.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2HC_2 PF13913.1 EPS31052.1 - 0.0017 17.9 5.7 0.004 16.7 0.1 2.7 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 EPS31052.1 - 0.0018 18.3 4.1 0.54 10.4 0.0 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EPS31052.1 - 0.0033 17.5 4.6 0.0082 16.2 3.2 1.7 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding DUF2225 PF09986.4 EPS31052.1 - 0.4 10.0 2.3 0.38 10.1 0.5 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_6 PF13912.1 EPS31052.1 - 0.67 9.9 7.1 0.52 10.2 0.1 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger MFS_1 PF07690.11 EPS31053.1 - 2.8e-23 82.1 32.2 2.8e-23 82.1 22.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4282 PF14110.1 EPS31053.1 - 0.088 13.0 0.5 0.088 13.0 0.3 5.0 4 1 0 4 4 4 0 Domain of unknown function (DUF4282) YrhK PF14145.1 EPS31055.1 - 1.7 8.3 6.3 5.2 6.8 1.7 3.0 2 1 0 2 2 2 0 YrhK-like protein GATase PF00117.23 EPS31056.1 - 4.8e-37 127.2 0.0 8.1e-37 126.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 EPS31056.1 - 1.6e-32 111.0 0.0 3.3e-32 110.0 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.12 EPS31056.1 - 5.9e-08 31.9 0.0 6.1e-05 22.0 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 EPS31056.1 - 4e-07 29.6 0.0 1e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.11 EPS31056.1 - 0.0023 16.5 0.0 0.0047 15.5 0.0 1.4 1 0 0 1 1 1 1 tRNA methyl transferase QueC PF06508.8 EPS31056.1 - 0.091 12.0 0.0 0.23 10.7 0.0 1.6 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 EPS31056.1 - 0.16 11.4 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase MARVEL PF01284.18 EPS31057.1 - 3.7e-08 33.3 16.2 5.4e-08 32.7 11.2 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF2678 PF10856.3 EPS31057.1 - 0.53 10.0 3.7 0.14 11.8 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) MotB_plug PF13677.1 EPS31057.1 - 9.4 5.6 7.2 4.5 6.6 1.9 2.3 2 0 0 2 2 2 0 Membrane MotB of proton-channel complex MotA/MotB DnaJ-X PF14308.1 EPS31058.1 - 1.3e-72 243.3 6.2 1.3e-72 243.3 4.3 3.4 3 1 0 3 3 3 1 X-domain of DnaJ-containing DnaJ PF00226.26 EPS31058.1 - 1.2e-25 89.0 0.2 3.8e-25 87.4 0.2 2.0 1 0 0 1 1 1 1 DnaJ domain DIT1_PvcA PF05141.7 EPS31058.1 - 0.15 11.3 2.7 0.12 11.6 0.1 2.0 2 0 0 2 2 2 0 Pyoverdine/dityrosine biosynthesis protein SQS_PSY PF00494.14 EPS31059.1 - 3.9e-39 134.5 0.0 5.2e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase Syntaxin_2 PF14523.1 EPS31059.1 - 0.053 13.5 0.1 0.66 10.0 0.0 2.4 2 0 0 2 2 2 0 Syntaxin-like protein Peptidase_A4 PF01828.12 EPS31060.1 - 1.2e-81 272.7 9.0 1.4e-81 272.4 6.2 1.1 1 0 0 1 1 1 1 Peptidase A4 family FAD_binding_4 PF01565.18 EPS31061.1 - 6.4e-28 96.9 0.5 9.5e-28 96.4 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EPS31061.1 - 0.011 15.6 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 Berberine and berberine like TauD PF02668.11 EPS31063.1 - 1.5e-54 185.3 0.4 1.9e-54 185.0 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 EPS31063.1 - 0.016 15.6 0.1 9.5 6.8 0.0 2.4 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily AA_permease PF00324.16 EPS31064.1 - 4.7e-112 374.7 43.0 5.8e-112 374.4 29.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPS31064.1 - 4.9e-28 97.8 45.7 6.6e-28 97.4 31.7 1.0 1 0 0 1 1 1 1 Amino acid permease ADH_N PF08240.7 EPS31066.1 - 9.7e-29 99.3 0.9 9.7e-29 99.3 0.7 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPS31066.1 - 7.8e-25 86.9 0.0 1.7e-24 85.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 EPS31066.1 - 0.013 15.6 0.0 0.021 14.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPS31066.1 - 0.059 13.2 0.2 0.1 12.4 0.1 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ADH_N_assoc PF13823.1 EPS31066.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated AA_permease_2 PF13520.1 EPS31068.1 - 9.9e-47 159.4 53.6 1.2e-46 159.0 37.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPS31068.1 - 5.1e-31 107.5 46.5 6.8e-31 107.1 32.2 1.0 1 0 0 1 1 1 1 Amino acid permease GAPT PF11770.3 EPS31068.1 - 0.029 14.0 1.1 0.092 12.4 0.8 1.8 2 0 0 2 2 2 0 GRB2-binding adapter (GAPT) DUF1469 PF07332.6 EPS31068.1 - 0.58 9.8 0.0 0.58 9.8 0.0 5.5 6 1 1 7 7 7 0 Protein of unknown function (DUF1469) CTV_P6 PF06706.6 EPS31068.1 - 2.5 7.6 8.5 0.39 10.2 0.1 3.4 3 0 0 3 3 3 0 Citrus tristeza virus 6-kDa protein Cellulase PF00150.13 EPS31069.1 - 2.1e-19 69.8 0.7 3.1e-19 69.2 0.5 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 EPS31069.1 - 1.3e-13 50.3 16.5 3.4e-13 48.9 11.5 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_2_C PF02836.12 EPS31069.1 - 0.00061 18.7 0.1 0.0014 17.6 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase-like PF12876.2 EPS31069.1 - 0.0038 17.6 0.0 0.009 16.4 0.0 1.7 1 1 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_42 PF02449.10 EPS31069.1 - 0.014 14.5 0.1 0.027 13.6 0.0 1.4 1 0 0 1 1 1 0 Beta-galactosidase Mucin PF01456.12 EPS31069.1 - 1.3 8.8 30.3 0.047 13.4 16.9 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein MSP1_C PF07462.6 EPS31069.1 - 8 4.7 5.7 32 2.7 4.7 1.4 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus ArabFuran-catal PF09206.6 EPS31070.1 - 0.036 13.0 0.0 0.036 13.0 0.0 1.1 1 0 0 1 1 1 0 Alpha-L-arabinofuranosidase B, catalytic Sugar_tr PF00083.19 EPS31071.1 - 1.4e-146 488.6 25.5 1.6e-146 488.4 17.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS31071.1 - 2e-23 82.6 33.9 7.7e-17 61.0 6.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_75 PF07335.6 EPS31072.1 - 3e-47 160.4 0.3 4.2e-47 159.9 0.2 1.2 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 DUF605 PF04652.11 EPS31072.1 - 0.42 9.9 28.7 0.56 9.5 19.9 1.1 1 0 0 1 1 1 0 Vta1 like AMP-binding PF00501.23 EPS31073.1 - 5.1e-92 308.4 0.1 6.6e-92 308.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPS31073.1 - 4.6e-13 49.9 0.0 1.2e-12 48.5 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PTPLA PF04387.9 EPS31074.1 - 3.1e-44 150.2 14.5 6.7e-44 149.2 10.0 1.5 1 1 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA DUF2183 PF09949.4 EPS31075.1 - 2.9e-19 68.8 0.1 4.8e-19 68.1 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Methyltransf_23 PF13489.1 EPS31076.1 - 1.3e-18 67.2 0.0 1.7e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPS31076.1 - 1.9e-16 60.3 0.0 4.4e-16 59.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPS31076.1 - 9.2e-16 57.7 0.0 2.3e-15 56.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPS31076.1 - 2.8e-15 56.5 0.0 5.9e-15 55.5 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS31076.1 - 4.3e-13 49.8 0.0 6.3e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPS31076.1 - 2.9e-07 29.8 0.0 1e-06 28.0 0.0 1.8 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EPS31076.1 - 4.9e-07 30.0 0.0 8.9e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPS31076.1 - 1.6e-06 28.1 0.0 3.4e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 EPS31076.1 - 6.5e-06 25.6 0.0 0.00017 21.0 0.0 2.0 2 0 0 2 2 2 1 Nodulation protein S (NodS) Methyltransf_16 PF10294.4 EPS31076.1 - 2e-05 24.1 0.0 4.4e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Putative methyltransferase RrnaAD PF00398.15 EPS31076.1 - 5.4e-05 22.3 0.0 8.3e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.9 EPS31076.1 - 0.00086 18.7 0.0 0.0021 17.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.8 EPS31076.1 - 0.00091 18.4 0.0 0.0013 17.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) DREV PF05219.7 EPS31076.1 - 0.0028 16.5 0.0 0.0062 15.4 0.0 1.5 2 0 0 2 2 2 1 DREV methyltransferase PCMT PF01135.14 EPS31076.1 - 0.0033 16.9 0.0 0.0091 15.5 0.0 1.7 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 EPS31076.1 - 0.02 13.9 0.0 0.24 10.4 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase DUF938 PF06080.7 EPS31076.1 - 0.11 11.9 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_9 PF08003.6 EPS31076.1 - 0.12 11.1 0.1 0.34 9.5 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) Pox_MCEL PF03291.11 EPS31076.1 - 0.15 10.8 0.0 0.41 9.4 0.0 1.7 1 1 0 1 1 1 0 mRNA capping enzyme Peptidase_S10 PF00450.17 EPS31077.1 - 7.6e-107 358.0 10.0 9.2e-107 357.7 6.9 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF4246 PF14033.1 EPS31078.1 - 4.7e-119 398.2 1.5 6.1e-119 397.8 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) NPP1 PF05630.6 EPS31080.1 - 2e-80 269.4 0.3 2.6e-80 269.0 0.2 1.1 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) DEC-1_N PF04625.8 EPS31081.1 - 4.4 5.8 11.8 6 5.4 8.2 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Myb_DNA-bind_6 PF13921.1 EPS31083.1 - 4.9e-05 23.3 0.2 0.00012 22.1 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EPS31083.1 - 0.00048 20.1 0.1 0.00087 19.3 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain AAA PF00004.24 EPS31085.1 - 1.6e-13 51.0 0.0 2.3e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EPS31085.1 - 0.0031 17.2 0.0 0.0064 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EPS31085.1 - 0.12 12.5 0.2 21 5.2 0.0 2.4 2 1 1 3 3 3 0 AAA domain KaiC PF06745.8 EPS31085.1 - 0.16 11.1 0.2 6.2 5.8 0.1 2.1 1 1 1 2 2 2 0 KaiC Ank_2 PF12796.2 EPS31086.1 - 9.4e-18 64.3 0.0 1.6e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EPS31086.1 - 4.1e-17 61.0 0.0 3.1e-07 29.8 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EPS31086.1 - 9.8e-16 57.4 0.1 2.1e-08 34.1 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPS31086.1 - 3.6e-14 51.4 0.0 1.3e-05 24.9 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EPS31086.1 - 4.7e-12 46.0 0.0 5.1e-11 42.7 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) GATase_7 PF13537.1 EPS31086.1 - 0.054 13.2 0.0 0.96 9.1 0.0 2.4 2 0 0 2 2 2 0 Glutamine amidotransferase domain Peroxidase_2 PF01328.12 EPS31088.1 - 8.8e-25 87.0 0.0 1.4e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 RicinB_lectin_2 PF14200.1 EPS31089.1 - 5.6e-06 26.6 0.6 0.0041 17.4 0.2 2.3 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EPS31089.1 - 0.0031 17.5 0.1 0.14 12.1 0.0 2.4 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain Asp PF00026.18 EPS31090.1 - 3.5e-35 121.7 5.0 1.1e-26 93.9 0.6 3.0 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 EPS31090.1 - 0.00045 20.1 0.3 0.24 11.3 0.0 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal DUF1469 PF07332.6 EPS31091.1 - 0.035 13.8 0.2 0.054 13.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) XhlA PF10779.4 EPS31091.1 - 0.05 13.5 0.0 0.05 13.5 0.0 2.3 3 0 0 3 3 3 0 Haemolysin XhlA DASH_Duo1 PF08651.5 EPS31091.1 - 0.13 11.8 0.1 0.91 9.1 0.0 2.3 2 0 0 2 2 2 0 DASH complex subunit Duo1 PAP2 PF01569.16 EPS31092.1 - 1.1e-18 67.0 0.0 1.8e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 PAP2 superfamily Reprolysin_5 PF13688.1 EPS31093.1 - 2.1e-05 24.5 0.0 3.3e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EPS31093.1 - 2.6e-05 24.3 0.0 3.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EPS31093.1 - 3.8e-05 23.2 0.0 5.2e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.3 EPS31093.1 - 0.00018 20.9 0.0 0.00029 20.2 0.0 1.3 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Peptidase_M10 PF00413.19 EPS31093.1 - 0.0007 19.3 0.3 0.0021 17.7 0.2 1.9 1 1 0 1 1 1 1 Matrixin Peptidase_M43 PF05572.8 EPS31093.1 - 0.0018 17.8 0.0 0.003 17.1 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Peptidase_M66 PF10462.4 EPS31093.1 - 0.015 14.2 0.1 0.022 13.6 0.1 1.2 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_3 PF13582.1 EPS31093.1 - 0.021 15.3 0.0 0.052 14.0 0.0 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M64 PF09471.5 EPS31093.1 - 0.041 13.4 0.0 0.2 11.2 0.0 1.9 2 0 0 2 2 2 0 IgA Peptidase M64 DUF3152 PF11350.3 EPS31093.1 - 0.062 12.8 0.0 0.098 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3152) Astacin PF01400.19 EPS31093.1 - 0.069 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Peptidase_M6 PF05547.6 EPS31095.1 - 1.7e-26 92.4 8.8 1.1e-22 79.8 2.8 2.6 1 1 0 2 2 2 2 Immune inhibitor A peptidase M6 FAD_binding_4 PF01565.18 EPS31096.1 - 1e-06 28.2 0.2 3e-06 26.7 0.2 1.7 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EPS31096.1 - 7.1e-06 25.8 0.0 1.8e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like GMC_oxred_N PF00732.14 EPS31097.1 - 6.8e-06 25.4 0.0 4.4e-05 22.7 0.0 2.3 2 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EPS31097.1 - 1.2e-05 25.6 0.1 3.6e-05 24.0 0.1 1.9 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EPS31097.1 - 0.0029 16.5 0.1 0.0054 15.6 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EPS31097.1 - 0.023 14.5 0.0 0.076 12.8 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPS31097.1 - 0.073 13.4 0.0 0.24 11.8 0.0 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EPS31097.1 - 0.12 11.4 0.1 0.18 10.8 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Acetyltransf_1 PF00583.19 EPS31099.1 - 8.7e-10 38.5 0.1 1.3e-09 37.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EPS31099.1 - 1.4e-08 34.8 0.1 3.1e-08 33.7 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EPS31099.1 - 3.8e-08 33.3 0.0 9.9e-08 32.0 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPS31099.1 - 3.6e-05 23.6 0.0 0.0013 18.6 0.0 2.5 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Ribonuclease PF00545.15 EPS31100.1 - 4.2e-12 45.9 1.1 5.9e-12 45.5 0.8 1.3 1 0 0 1 1 1 1 ribonuclease DUF3632 PF12311.3 EPS31101.1 - 5.9e-31 107.6 4.8 8.7e-31 107.1 3.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) DUF4347 PF14252.1 EPS31101.1 - 0.05 13.0 0.1 0.93 8.9 0.1 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4347) Fungal_trans PF04082.13 EPS31102.1 - 2.5e-12 46.2 0.3 3.9e-12 45.5 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS31102.1 - 0.00017 21.4 1.7 0.00033 20.4 1.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydr_30_2 PF14587.1 EPS31103.1 - 1.9e-18 66.5 3.8 3.7e-18 65.6 2.6 1.4 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 AMP-binding PF00501.23 EPS31104.1 - 1e-82 277.7 0.0 1.3e-82 277.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPS31104.1 - 1.9e-11 44.7 0.1 4.7e-11 43.4 0.1 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TFIID_20kDa PF03847.8 EPS31105.1 - 0.044 14.0 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A HSP70 PF00012.15 EPS31105.1 - 0.35 8.7 0.9 9.9 3.9 0.0 2.6 3 0 0 3 3 3 0 Hsp70 protein T4SS PF07996.6 EPS31106.1 - 0.036 13.9 0.3 0.054 13.3 0.2 1.2 1 0 0 1 1 1 0 Type IV secretion system proteins APG6 PF04111.7 EPS31106.1 - 0.56 9.1 5.8 0.83 8.6 4.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 EPS31106.1 - 1 8.9 4.4 1.6 8.2 3.0 1.3 1 0 0 1 1 1 0 IncA protein PEP_mutase PF13714.1 EPS31107.1 - 2.5e-46 157.8 0.0 2.9e-46 157.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 EPS31107.1 - 2.6e-22 78.7 0.1 3.8e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 Isocitrate lyase family DUF1275 PF06912.6 EPS31109.1 - 1.6e-45 154.9 4.9 1.9e-45 154.6 3.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF2484 PF10658.4 EPS31109.1 - 0.054 13.6 1.7 0.054 13.6 1.2 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2484) Glyco_hydro_43 PF04616.9 EPS31112.1 - 1.9e-49 168.2 5.8 1.9e-49 168.2 4.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 CBM_6 PF03422.10 EPS31112.1 - 4.3e-37 127.0 4.8 1.3e-36 125.4 3.3 1.9 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) Glyco_hydro_32N PF00251.15 EPS31112.1 - 0.0002 20.8 2.8 0.00046 19.6 2.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Kelch_3 PF13415.1 EPS31112.1 - 0.1 12.8 3.2 0.15 12.2 0.1 2.7 2 1 0 2 2 2 0 Galactose oxidase, central domain Pec_lyase_C PF00544.14 EPS31113.1 - 1.7e-46 158.2 12.8 2.7e-46 157.6 8.9 1.3 1 0 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 EPS31113.1 - 0.016 14.9 25.2 0.012 15.3 12.6 3.0 1 1 2 3 3 3 0 Right handed beta helix region FAD_binding_3 PF01494.14 EPS31114.1 - 2.9e-15 56.2 0.1 6e-15 55.1 0.1 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EPS31114.1 - 3.1e-08 32.9 0.3 2.1e-06 26.8 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPS31114.1 - 9.7e-06 25.5 0.0 3.5e-05 23.7 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EPS31114.1 - 3.5e-05 23.6 0.0 0.0012 18.6 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EPS31114.1 - 0.0029 16.3 0.4 0.054 12.1 0.0 2.6 3 0 0 3 3 3 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 EPS31114.1 - 0.01 15.6 0.0 0.039 13.8 0.0 1.9 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPS31114.1 - 0.022 13.8 0.0 0.043 12.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family MFS_1 PF07690.11 EPS31116.1 - 3.9e-20 71.8 37.8 2.9e-17 62.4 11.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4440 PF14534.1 EPS31117.1 - 4e-09 36.6 0.0 4.6e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.2 EPS31117.1 - 0.022 15.1 0.0 0.033 14.5 0.0 1.4 1 1 0 1 1 1 0 SnoaL-like domain DUF1348 PF07080.6 EPS31119.1 - 3.1e-46 156.7 2.6 4e-46 156.3 1.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.2 EPS31119.1 - 3.7e-08 33.6 0.9 5.1e-08 33.2 0.6 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 EPS31119.1 - 2.8e-07 30.7 0.5 3.5e-07 30.3 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.7 EPS31119.1 - 0.0041 16.6 0.1 0.0066 16.0 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_4 PF13577.1 EPS31119.1 - 0.049 13.5 0.7 0.095 12.6 0.5 1.8 1 1 0 1 1 1 0 SnoaL-like domain NUP PF06516.6 EPS31120.1 - 2.1e-128 427.5 0.0 2.5e-128 427.3 0.0 1.0 1 0 0 1 1 1 1 Purine nucleoside permease (NUP) adh_short PF00106.20 EPS31121.1 - 2.2e-19 69.9 0.0 3.5e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPS31121.1 - 3.6e-07 30.2 0.0 4.8e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPS31121.1 - 5.4e-06 26.1 0.0 1e-05 25.2 0.0 1.4 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.5 EPS31121.1 - 0.0025 16.9 0.0 0.0038 16.4 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Glyco_hydro_4 PF02056.11 EPS31121.1 - 0.026 13.8 0.0 0.052 12.8 0.0 1.5 1 1 0 1 1 1 0 Family 4 glycosyl hydrolase Eno-Rase_NADH_b PF12242.3 EPS31121.1 - 0.061 13.1 0.4 0.2 11.4 0.1 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase MFS_1 PF07690.11 EPS31122.1 - 7.8e-35 120.2 27.8 3e-34 118.3 19.2 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily ADH_zinc_N PF00107.21 EPS31124.1 - 5e-25 87.5 0.0 7.7e-25 86.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPS31124.1 - 1.2e-19 71.4 0.0 3e-19 70.1 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPS31124.1 - 2.2e-11 43.4 1.3 3.9e-11 42.6 0.2 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain GDPD PF03009.12 EPS31125.1 - 7.7e-32 110.7 0.0 1.3e-31 110.0 0.0 1.4 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 EPS31125.1 - 3.6e-06 27.0 0.4 8e-06 25.8 0.3 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family HNH_2 PF13391.1 EPS31126.1 - 3e-05 23.7 0.1 7e-05 22.5 0.1 1.7 1 0 0 1 1 1 1 HNH endonuclease CENP-F_leu_zip PF10473.4 EPS31126.1 - 0.054 13.3 1.1 0.12 12.2 0.8 1.5 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MFS_1 PF07690.11 EPS31127.1 - 1.8e-39 135.5 28.7 1.8e-39 135.5 19.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS31127.1 - 8.8e-13 47.6 28.9 3.6e-11 42.3 20.1 3.1 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2304 PF10066.4 EPS31127.1 - 0.24 11.2 2.4 1.6 8.5 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) OATP PF03137.15 EPS31127.1 - 1.5 6.7 10.6 0.074 11.0 1.0 2.5 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Lactamase_B PF00753.22 EPS31128.1 - 2.4e-05 24.0 0.1 2.8e-05 23.8 0.1 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily FAD_binding_3 PF01494.14 EPS31129.1 - 5.1e-05 22.4 1.3 0.00011 21.3 0.8 1.7 1 1 1 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EPS31129.1 - 0.00076 19.4 0.1 0.0016 18.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EPS31129.1 - 0.0085 15.2 0.1 0.018 14.1 0.0 1.5 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 EPS31129.1 - 0.067 12.0 0.1 0.076 11.9 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPS31129.1 - 0.16 10.8 0.5 7 5.3 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Fungal_trans PF04082.13 EPS31130.1 - 5.4e-12 45.1 0.0 8.3e-12 44.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS31130.1 - 2.7e-06 27.1 13.9 5.2e-06 26.2 9.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Imm42 PF15601.1 EPS31130.1 - 0.12 11.7 0.1 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 42 LIM PF00412.17 EPS31131.1 - 1.1e-17 63.8 18.0 9.5e-12 44.8 1.4 3.1 3 0 0 3 3 3 2 LIM domain DUF3419 PF11899.3 EPS31132.1 - 1.5e-154 514.3 0.0 2e-154 513.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 EPS31132.1 - 8.2e-14 51.6 0.0 4e-11 42.8 0.0 3.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPS31132.1 - 3.4e-10 39.7 0.0 4.6e-09 36.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS31132.1 - 3.1e-09 37.3 0.0 2.7e-08 34.3 0.0 2.5 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPS31132.1 - 3.3e-08 33.9 0.0 1.2e-07 32.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPS31132.1 - 1.8e-07 31.2 0.0 1.8e-06 27.9 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPS31132.1 - 1.1e-06 28.9 0.0 0.0003 21.2 0.0 3.5 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPS31132.1 - 5.6e-06 25.6 0.0 1.6e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EPS31132.1 - 9.9e-06 25.8 0.0 7.3e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 EPS31132.1 - 0.00011 21.8 0.0 0.00026 20.5 0.0 1.6 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 EPS31132.1 - 0.002 17.8 0.0 0.0052 16.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EPS31132.1 - 0.091 11.7 0.0 0.22 10.4 0.0 1.6 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_28 PF02636.12 EPS31132.1 - 0.1 11.9 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF3096 PF11295.3 EPS31132.1 - 6.2 6.4 5.7 13 5.3 4.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3096) Fungal_trans PF04082.13 EPS31133.1 - 3.3e-19 68.7 0.0 5.9e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS31133.1 - 2.5e-05 24.0 17.5 6e-05 22.8 12.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SBP_bac_8 PF13416.1 EPS31134.1 - 0.0086 15.8 1.5 0.011 15.4 1.1 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein Cu-oxidase_2 PF07731.9 EPS31135.1 - 1.7e-20 72.9 0.1 3e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.17 EPS31135.1 - 1e-11 45.0 0.0 2.4e-11 43.7 0.0 1.5 1 1 0 1 1 1 1 Multicopper oxidase Ferric_reduct PF01794.14 EPS31136.1 - 5e-16 58.9 18.1 5e-16 58.9 12.5 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EPS31136.1 - 3.1e-13 49.5 0.0 6.3e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EPS31136.1 - 3.9e-09 36.6 0.0 3e-08 33.6 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 EPS31136.1 - 0.17 12.4 0.0 28 5.3 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Ctr PF04145.10 EPS31138.1 - 5.1e-33 114.1 0.0 8.7e-33 113.3 0.0 1.4 1 1 0 1 1 1 1 Ctr copper transporter family DUF1469 PF07332.6 EPS31138.1 - 0.26 11.0 2.5 0.54 9.9 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) DIT1_PvcA PF05141.7 EPS31139.1 - 8.7e-56 189.2 0.0 1.4e-55 188.5 0.0 1.3 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein AMP-binding PF00501.23 EPS31139.1 - 3.5e-24 84.9 0.0 6.6e-24 84.0 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme Transferase PF02458.10 EPS31139.1 - 6.3e-13 47.9 0.0 2.7e-05 22.7 0.0 3.1 3 0 0 3 3 3 3 Transferase family PP-binding PF00550.20 EPS31139.1 - 1.7e-07 31.3 0.1 4.8e-07 29.9 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site MFS_1 PF07690.11 EPS31140.1 - 6.2e-42 143.5 57.8 3.6e-31 108.1 16.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EPS31140.1 - 1.1e-05 23.8 21.0 6.1e-05 21.4 14.6 2.1 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EPS31141.1 - 5.4e-22 77.9 59.5 1.3e-13 50.3 22.9 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EPS31141.1 - 0.00041 18.8 52.3 0.0045 15.4 11.3 3.1 2 1 1 3 3 3 3 MFS/sugar transport protein DUF2976 PF11190.3 EPS31141.1 - 0.026 14.0 13.5 1.1 8.8 1.1 4.6 5 0 0 5 5 5 0 Protein of unknown function (DUF2976) DUF2852 PF11014.3 EPS31141.1 - 1.4 8.9 3.8 0.72 9.8 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2852) PAXIP1_C PF15364.1 EPS31144.1 - 0.0063 16.4 0.0 0.0079 16.1 0.0 1.1 1 0 0 1 1 1 1 PAXIP1-associated-protein-1 C term PTIP binding protein DHquinase_I PF01487.10 EPS31145.1 - 3.3e-58 196.9 0.0 4.6e-58 196.5 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase zf-RING_2 PF13639.1 EPS31146.1 - 1.9e-06 27.6 5.1 4.8e-06 26.3 3.6 1.7 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 EPS31146.1 - 0.0016 18.3 7.9 0.0023 17.8 3.2 2.2 2 0 0 2 2 2 1 FANCL C-terminal domain zf-Apc11 PF12861.2 EPS31146.1 - 0.0024 17.6 2.3 0.0024 17.6 1.6 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EPS31146.1 - 0.0048 16.8 5.6 0.011 15.7 3.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EPS31146.1 - 0.0062 16.2 5.7 0.012 15.2 3.9 1.5 1 0 0 1 1 1 1 PHD-finger SWIM PF04434.12 EPS31146.1 - 0.016 14.6 0.1 0.029 13.8 0.1 1.5 1 0 0 1 1 1 0 SWIM zinc finger Prok-RING_1 PF14446.1 EPS31146.1 - 0.038 13.7 4.5 0.044 13.5 2.3 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 zf-rbx1 PF12678.2 EPS31146.1 - 0.12 12.5 5.2 0.052 13.6 1.4 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger zf-RING-like PF08746.6 EPS31146.1 - 0.29 11.1 3.6 1.4 9.0 2.5 2.2 1 1 0 1 1 1 0 RING-like domain zf-RING_5 PF14634.1 EPS31146.1 - 0.31 10.8 10.8 0.026 14.2 3.6 2.1 2 0 0 2 2 2 0 zinc-RING finger domain RINGv PF12906.2 EPS31146.1 - 0.43 10.6 6.5 1 9.4 4.5 1.7 1 0 0 1 1 1 0 RING-variant domain C1_1 PF00130.17 EPS31146.1 - 1.3 8.7 6.5 0.28 10.9 1.7 1.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF974 PF06159.8 EPS31147.1 - 6e-79 265.0 0.0 7.3e-79 264.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) PhaC_N PF07167.8 EPS31147.1 - 0.00093 18.6 0.1 0.0099 15.3 0.0 2.4 2 1 1 3 3 3 1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus DENN PF02141.16 EPS31148.1 - 8.5e-56 188.6 0.1 1.4e-55 187.8 0.1 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.14 EPS31148.1 - 4.1e-19 68.4 1.1 9.1e-19 67.3 0.8 1.6 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.13 EPS31148.1 - 2.4e-16 59.4 0.1 1.3e-15 57.1 0.0 2.2 2 0 0 2 2 2 1 uDENN domain C1_1 PF00130.17 EPS31148.1 - 6.4e-05 22.5 6.8 0.00012 21.7 4.7 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) FDF PF09532.5 EPS31148.1 - 0.02 15.4 0.0 0.066 13.7 0.0 2.0 1 0 0 1 1 1 0 FDF domain DUF4042 PF13251.1 EPS31148.1 - 0.059 12.8 0.1 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4042) zf-HC5HC2H_2 PF13832.1 EPS31148.1 - 0.086 12.8 7.3 0.13 12.2 3.2 2.2 2 0 0 2 2 2 0 PHD-zinc-finger like domain SPA PF08616.5 EPS31148.1 - 0.099 12.3 0.1 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis CENP-K PF11802.3 EPS31148.1 - 0.29 10.3 0.9 0.5 9.5 0.6 1.2 1 0 0 1 1 1 0 Centromere-associated protein K PHD PF00628.24 EPS31148.1 - 0.46 10.2 8.6 0.21 11.2 3.9 2.0 1 1 1 2 2 2 0 PHD-finger C1_3 PF07649.7 EPS31148.1 - 2 8.5 8.3 0.16 12.0 2.1 2.0 2 0 0 2 2 2 0 C1-like domain CENP-N PF05238.8 EPS31149.1 - 1.6e-128 429.2 0.0 1.8e-128 429.0 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like bZIP_2 PF07716.10 EPS31150.1 - 1.4e-12 47.2 12.1 5.2e-12 45.4 8.4 2.0 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EPS31150.1 - 1e-05 25.3 7.8 1e-05 25.3 5.4 2.2 3 0 0 3 3 3 1 bZIP transcription factor CCDC144C PF14915.1 EPS31150.1 - 0.00062 18.7 3.5 0.00062 18.7 2.4 1.6 2 0 0 2 2 2 1 CCDC144C protein coiled-coil region PvlArgDC PF01862.11 EPS31150.1 - 0.038 13.5 0.5 0.063 12.8 0.1 1.5 1 1 0 1 1 1 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) TFIIA PF03153.8 EPS31150.1 - 0.56 10.0 9.9 0.72 9.6 6.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DDRGK PF09756.4 EPS31150.1 - 1.2 8.5 12.0 1.9 7.8 8.3 1.3 1 0 0 1 1 1 0 DDRGK domain IncA PF04156.9 EPS31150.1 - 5.2 6.6 8.8 1.2 8.6 3.6 1.8 2 0 0 2 2 2 0 IncA protein DNA_pol_viral_N PF00242.12 EPS31150.1 - 8.4 5.3 11.8 11 4.8 8.2 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Methyltransf_18 PF12847.2 EPS31151.1 - 0.053 14.0 0.1 0.2 12.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain NAD_binding_8 PF13450.1 EPS31152.1 - 1.6e-14 53.7 0.0 3.1e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EPS31152.1 - 8.3e-07 28.2 0.2 0.00018 20.5 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EPS31152.1 - 8.6e-05 21.7 0.1 0.52 9.3 0.1 3.1 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 EPS31152.1 - 0.0013 18.6 0.0 0.0047 16.8 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Semialdhyde_dh PF01118.19 EPS31152.1 - 0.004 17.4 0.1 0.37 11.1 0.0 2.4 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 EPS31152.1 - 0.0051 16.6 0.1 0.034 13.9 0.0 2.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EPS31152.1 - 0.007 15.2 0.0 0.0098 14.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 EPS31152.1 - 0.0071 15.4 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EPS31152.1 - 0.0072 16.7 0.0 0.084 13.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EPS31152.1 - 0.02 13.8 0.1 0.21 10.4 0.0 2.3 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 EPS31152.1 - 0.022 13.3 0.0 0.033 12.8 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase F420_oxidored PF03807.12 EPS31152.1 - 0.084 13.3 0.2 16 5.9 0.0 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Lycopene_cycl PF05834.7 EPS31152.1 - 0.1 11.5 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein DUF2366 PF10171.4 EPS31152.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2366) HI0933_like PF03486.9 EPS31152.1 - 0.17 10.2 0.0 0.29 9.5 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein UBN2_3 PF14244.1 EPS31153.1 - 0.0052 16.3 0.0 0.0067 16.0 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type HATPase_c_3 PF13589.1 EPS31156.1 - 1.5e-15 57.0 0.0 2.7e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 EPS31156.1 - 2.2e-08 33.7 0.0 3.1e-07 30.1 0.0 2.5 3 0 0 3 3 3 1 MutL C terminal dimerisation domain HATPase_c PF02518.21 EPS31156.1 - 0.00032 20.3 0.0 0.00067 19.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase RasGEF PF00617.14 EPS31157.1 - 8.7e-54 182.0 0.0 1.7e-53 181.1 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EPS31157.1 - 3.5e-18 65.6 0.0 9.9e-18 64.1 0.0 1.8 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.1 EPS31157.1 - 1.5e-06 27.7 0.0 2.8e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EPS31157.1 - 2.1e-05 23.8 0.0 4.2e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 SH3 domain 2OG-FeII_Oxy_5 PF13759.1 EPS31158.1 - 0.15 12.3 3.3 0.16 12.2 2.3 1.1 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Med5 PF08689.5 EPS31160.1 - 1.5e-289 963.0 0.0 8e-289 960.6 0.0 1.7 1 1 0 1 1 1 1 Mediator complex subunit Med5 Mto2_bdg PF12808.2 EPS31160.1 - 0.42 10.7 2.8 0.24 11.5 0.1 2.1 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region WRC PF08879.5 EPS31161.1 - 0.031 13.9 0.2 0.044 13.4 0.2 1.3 1 0 0 1 1 1 0 WRC ELFV_dehydrog PF00208.16 EPS31162.1 - 1.9e-84 283.0 2.4 2.4e-84 282.7 1.7 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 EPS31162.1 - 7.7e-49 164.6 0.0 1.3e-48 163.8 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Gag_p10 PF02337.12 EPS31165.1 - 0.15 11.7 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Retroviral GAG p10 protein MFS_1 PF07690.11 EPS31166.1 - 5.2e-11 41.8 29.9 5.2e-11 41.8 20.8 3.6 2 2 1 3 3 3 2 Major Facilitator Superfamily DUF997 PF06196.7 EPS31166.1 - 0.013 15.0 2.5 2.3 7.7 0.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF997) Metallophos PF00149.23 EPS31167.1 - 2.5e-10 40.0 1.6 4e-10 39.4 1.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ank_2 PF12796.2 EPS31168.1 - 1.2e-50 169.7 10.5 1.1e-12 48.0 1.2 5.7 5 0 0 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPS31168.1 - 2e-30 104.6 9.8 0.00064 20.1 0.0 9.1 5 1 5 10 10 10 9 Ankyrin repeats (many copies) Ank PF00023.25 EPS31168.1 - 4.2e-30 102.0 24.6 0.017 14.8 0.1 13.3 15 0 0 15 15 13 7 Ankyrin repeat Ank_3 PF13606.1 EPS31168.1 - 4.7e-30 100.6 15.2 0.072 13.3 0.0 14.6 15 0 0 15 15 14 7 Ankyrin repeat Ank_5 PF13857.1 EPS31168.1 - 2.6e-25 87.8 22.7 0.014 15.6 0.0 11.8 4 2 9 13 13 13 7 Ankyrin repeats (many copies) NACHT PF05729.7 EPS31168.1 - 7.9e-11 41.8 0.2 1.3e-09 37.9 0.0 2.5 2 0 0 2 2 2 1 NACHT domain DUF3447 PF11929.3 EPS31168.1 - 1.8e-09 37.2 0.0 0.61 9.9 0.0 6.7 3 2 4 7 7 7 1 Domain of unknown function (DUF3447) AAA_16 PF13191.1 EPS31168.1 - 8.5e-07 29.1 0.2 4.3e-06 26.8 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EPS31168.1 - 0.00027 21.0 0.0 0.00098 19.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EPS31168.1 - 0.00028 20.5 0.1 0.00076 19.1 0.1 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EPS31168.1 - 0.0057 16.8 0.0 0.058 13.5 0.0 2.4 2 0 0 2 2 2 1 RNA helicase PIF1 PF05970.9 EPS31168.1 - 0.0067 15.4 0.1 0.017 14.0 0.0 1.7 2 0 0 2 2 2 1 PIF1-like helicase AAA_25 PF13481.1 EPS31168.1 - 0.0075 15.6 0.0 0.019 14.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 EPS31168.1 - 0.016 14.7 0.0 0.041 13.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 EPS31168.1 - 0.017 14.8 0.0 0.063 13.0 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain Shigella_OspC PF06128.6 EPS31168.1 - 0.023 14.2 2.3 8.3 5.8 0.0 4.1 2 2 1 4 4 4 0 Shigella flexneri OspC protein AAA PF00004.24 EPS31168.1 - 0.03 14.5 0.2 0.14 12.3 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EPS31168.1 - 0.035 13.5 0.1 0.15 11.4 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein SyrA PF11089.3 EPS31168.1 - 1.1 9.0 3.7 12 5.7 0.2 2.9 3 0 0 3 3 3 0 Exopolysaccharide production repressor SLT PF01464.15 EPS31169.1 - 0.00013 21.4 1.5 0.0012 18.3 0.7 2.6 2 1 0 2 2 2 1 Transglycosylase SLT domain LysM PF01476.15 EPS31169.1 - 0.00041 20.1 0.0 0.0015 18.3 0.0 2.0 1 0 0 1 1 1 1 LysM domain HrpF PF06266.7 EPS31169.1 - 0.041 14.0 0.2 0.55 10.4 0.0 2.4 2 0 0 2 2 2 0 HrpF protein Lysozyme_like PF13702.1 EPS31169.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Lysozyme-like DUF605 PF04652.11 EPS31169.1 - 8.1 5.7 14.4 12 5.1 10.0 1.1 1 0 0 1 1 1 0 Vta1 like DPBB_1 PF03330.13 EPS31170.1 - 0.00071 19.5 0.0 0.0021 18.0 0.0 2.0 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Mitofilin PF09731.4 EPS31170.1 - 0.057 12.0 3.9 0.064 11.9 2.7 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein HisG_C PF08029.6 EPS31170.1 - 0.18 11.7 1.9 0.41 10.6 1.3 1.6 1 0 0 1 1 1 0 HisG, C-terminal domain TFIIA PF03153.8 EPS31170.1 - 1.8 8.4 14.0 2.2 8.0 9.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 EPS31170.1 - 3.6 5.7 7.4 4.5 5.4 5.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 THRAP3_BCLAF1 PF15440.1 EPS31170.1 - 4.6 5.7 7.5 5.4 5.5 5.2 1.0 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Macoilin PF09726.4 EPS31170.1 - 4.6 5.3 8.3 5.5 5.1 5.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Ribonuc_red_lgC PF02867.10 EPS31172.1 - 2.4e-213 709.5 0.0 3.7e-213 708.9 0.0 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EPS31172.1 - 5.3e-23 80.6 0.0 1.2e-22 79.5 0.0 1.6 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EPS31172.1 - 2.3e-16 59.9 0.2 7.5e-16 58.3 0.1 2.1 2 0 0 2 2 2 1 ATP cone domain Ribosomal_60s PF00428.14 EPS31172.1 - 0.22 11.9 6.5 0.79 10.1 4.5 1.9 1 0 0 1 1 1 0 60s Acidic ribosomal protein AAA_17 PF13207.1 EPS31174.1 - 7.5e-08 33.2 0.1 2.8e-06 28.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 EPS31174.1 - 2.1e-06 27.4 0.0 2.8e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 EPS31174.1 - 2.7e-05 24.4 0.0 0.00076 19.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.12 EPS31174.1 - 0.00079 18.8 0.0 0.49 9.7 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.1 EPS31174.1 - 0.0031 17.3 0.0 0.11 12.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EPS31174.1 - 0.0063 15.6 0.0 0.024 13.7 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.1 EPS31174.1 - 0.024 14.7 0.0 0.16 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EPS31174.1 - 0.038 13.9 0.0 0.15 12.0 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain KTI12 PF08433.5 EPS31174.1 - 0.058 12.6 0.0 0.091 11.9 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_28 PF13521.1 EPS31174.1 - 0.09 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EPS31174.1 - 0.11 11.4 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 EPS31174.1 - 0.13 11.1 0.0 0.2 10.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Viral_helicase1 PF01443.13 EPS31174.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NACHT PF05729.7 EPS31174.1 - 0.16 11.6 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Pkinase PF00069.20 EPS31176.1 - 5.4e-70 235.5 0.0 1.6e-69 233.9 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS31176.1 - 3.2e-50 170.6 0.0 7e-50 169.5 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPS31176.1 - 0.0016 17.4 0.0 0.011 14.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Arm PF00514.18 EPS31176.1 - 0.033 14.0 0.0 4.4 7.2 0.0 3.7 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DRIM PF07539.7 EPS31176.1 - 0.037 13.4 0.1 0.1 12.0 0.1 1.7 1 0 0 1 1 1 0 Down-regulated in metastasis ABC1 PF03109.11 EPS31177.1 - 1.5e-33 115.3 0.0 2.5e-33 114.5 0.0 1.4 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 EPS31177.1 - 0.17 11.1 0.0 0.4 10.0 0.0 1.5 1 0 0 1 1 1 0 RIO1 family NifU_N PF01592.11 EPS31178.1 - 2.9e-52 175.9 0.1 3.9e-52 175.5 0.0 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain Mito_carr PF00153.22 EPS31180.1 - 4.1e-66 218.7 0.0 1.2e-21 76.2 0.0 3.5 2 2 1 3 3 3 3 Mitochondrial carrier protein UCR_14kD PF02271.11 EPS31181.1 - 1.2e-45 153.5 0.1 1.4e-45 153.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit DUF4211 PF13926.1 EPS31181.1 - 0.004 16.5 0.1 0.0048 16.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) DUF1985 PF09331.6 EPS31181.1 - 0.061 13.1 0.0 0.075 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1985) HhH-GPD PF00730.20 EPS31182.1 - 1.3e-14 54.3 0.0 2.1e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HMG14_17 PF01101.13 EPS31182.1 - 2.7 8.7 14.1 0.58 10.8 4.4 2.4 2 0 0 2 2 2 0 HMG14 and HMG17 Ecm33 PF12454.3 EPS31183.1 - 6.6e-15 54.7 2.9 6.6e-15 54.7 2.0 2.3 2 0 0 2 2 2 1 GPI-anchored cell wall organization protein LRR_5 PF13306.1 EPS31183.1 - 2.2e-06 27.4 0.1 0.073 12.7 0.0 2.6 1 1 2 3 3 3 3 Leucine rich repeats (6 copies) DUF3450 PF11932.3 EPS31184.1 - 0.028 13.7 5.0 0.047 12.9 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Peptidase_S30 PF01577.11 EPS31184.1 - 0.064 12.6 0.3 0.11 11.9 0.2 1.2 1 0 0 1 1 1 0 Potyvirus P1 protease DivIC PF04977.10 EPS31184.1 - 0.13 11.7 1.7 0.27 10.7 1.2 1.6 1 0 0 1 1 1 0 Septum formation initiator DUF972 PF06156.8 EPS31184.1 - 0.21 11.9 4.1 0.27 11.6 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) NTR2 PF15458.1 EPS31184.1 - 3.1 6.9 10.8 1.1 8.5 5.4 1.7 2 0 0 2 2 2 0 Nineteen complex-related protein 2 Anp1 PF03452.9 EPS31186.1 - 3.3e-110 367.4 0.0 4e-110 367.2 0.0 1.1 1 0 0 1 1 1 1 Anp1 YCII PF03795.9 EPS31187.1 - 1.3e-09 38.1 0.0 1.5e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Peptidase_M24 PF00557.19 EPS31188.1 - 1.2e-45 155.6 0.1 1.5e-45 155.3 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DnaJ PF00226.26 EPS31189.1 - 3.7e-22 77.8 0.8 5.9e-22 77.1 0.5 1.3 1 0 0 1 1 1 1 DnaJ domain Porin_3 PF01459.17 EPS31190.1 - 5.5e-70 235.7 3.8 6.1e-70 235.6 2.6 1.0 1 0 0 1 1 1 1 Eukaryotic porin Asn_synthase PF00733.16 EPS31191.1 - 5.2e-69 232.5 0.0 7.1e-69 232.1 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EPS31191.1 - 7.7e-38 129.0 0.0 1.3e-37 128.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EPS31191.1 - 3.7e-29 101.3 0.0 8e-29 100.2 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EPS31191.1 - 1.4e-07 30.9 0.0 2.9e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 EPS31191.1 - 0.00054 18.7 0.0 0.34 9.5 0.0 2.8 1 1 2 3 3 3 2 Glutamine amidotransferases class-II NAD_synthase PF02540.12 EPS31191.1 - 0.0013 17.7 0.1 0.0052 15.7 0.0 2.1 2 1 0 2 2 2 1 NAD synthase UQ_con PF00179.21 EPS31192.1 - 6.8e-49 164.9 0.0 7.7e-49 164.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EPS31192.1 - 2.1e-05 24.2 0.0 5.2e-05 23.0 0.0 1.7 1 1 1 2 2 2 1 Prokaryotic E2 family B RWD PF05773.17 EPS31192.1 - 0.047 13.5 1.2 0.085 12.7 0.8 1.7 1 1 0 1 1 1 0 RWD domain G-patch PF01585.18 EPS31193.1 - 3.8e-10 39.4 1.6 7.6e-10 38.4 1.1 1.5 1 0 0 1 1 1 1 G-patch domain RRM_5 PF13893.1 EPS31193.1 - 1.6e-05 24.6 0.0 3.3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPS31193.1 - 2.2e-05 23.9 0.0 5.6e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS31193.1 - 0.048 13.6 0.0 0.096 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FA_desaturase PF00487.19 EPS31194.1 - 1.3e-25 90.3 13.8 2.2e-25 89.6 9.6 1.4 1 1 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 EPS31194.1 - 7.9e-20 69.8 0.1 1.4e-19 69.0 0.1 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Motile_Sperm PF00635.21 EPS31195.1 - 1.9e-26 91.8 0.5 5.8e-26 90.2 0.2 1.8 1 1 1 2 2 2 1 MSP (Major sperm protein) domain FixG_C PF11614.3 EPS31195.1 - 0.022 14.8 0.1 0.035 14.2 0.1 1.3 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase UBA PF00627.26 EPS31196.1 - 5.8e-06 25.9 3.5 6.9e-06 25.7 0.1 2.7 3 0 0 3 3 3 1 UBA/TS-N domain UBX PF00789.15 EPS31196.1 - 0.0032 17.4 0.1 0.0098 15.9 0.0 1.9 1 0 0 1 1 1 1 UBX domain Utp14 PF04615.8 EPS31196.1 - 0.0082 14.3 28.5 0.0091 14.2 19.7 1.0 1 0 0 1 1 1 1 Utp14 protein zf-C2H2 PF00096.21 EPS31196.1 - 0.025 14.9 0.3 0.046 14.0 0.2 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type Crystallin PF00525.13 EPS31196.1 - 0.06 13.5 0.1 0.11 12.7 0.1 1.3 1 0 0 1 1 1 0 Alpha crystallin A chain, N terminal zf-C2H2_jaz PF12171.3 EPS31196.1 - 0.064 13.4 0.2 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EPS31196.1 - 0.23 11.5 3.7 0.1 12.7 0.5 2.0 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) SOBP PF15279.1 EPS31196.1 - 0.81 10.0 7.5 1 9.6 5.2 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein GAGA_bind PF06217.7 EPS31196.1 - 1.2 9.0 13.3 1.8 8.4 9.2 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family Oxysterol_BP PF01237.13 EPS31196.1 - 3.2 6.1 14.2 4.1 5.7 9.9 1.2 1 0 0 1 1 1 0 Oxysterol-binding protein CAF-1_p150 PF11600.3 EPS31196.1 - 3.2 7.0 44.8 5.2 6.3 31.0 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal ACR_tran PF00873.14 EPS31196.1 - 5.2 4.3 8.5 6.3 4.0 5.9 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family V_ATPase_I PF01496.14 EPS31196.1 - 9.2 3.9 8.4 9.5 3.9 5.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Rad52_Rad22 PF04098.10 EPS31197.1 - 5.8e-61 204.7 0.1 7.8e-61 204.3 0.0 1.1 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Terpene_synth_C PF03936.11 EPS31199.1 - 8.7e-11 41.5 2.7 1.6e-10 40.6 1.9 1.4 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain Col_cuticle_N PF01484.12 EPS31199.1 - 2.2 8.0 5.4 2.4 7.8 0.1 2.6 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain adh_short PF00106.20 EPS31200.1 - 5.1e-23 81.8 0.0 7.6e-23 81.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPS31200.1 - 1e-08 35.0 0.0 1.9e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EPS31200.1 - 6.8e-06 26.0 0.0 0.022 14.5 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.14 EPS31200.1 - 0.1 11.2 0.0 0.19 10.3 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_32N PF00251.15 EPS31201.1 - 6.7e-45 153.7 5.1 9e-44 150.0 3.6 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 EPS31201.1 - 1.1e-15 57.7 0.3 3.1e-15 56.3 0.1 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal BNR PF02012.15 EPS31201.1 - 0.003 17.1 0.2 0.019 14.7 0.1 2.5 1 0 0 1 1 1 1 BNR/Asp-box repeat Strep_67kDa_ant PF06100.6 EPS31202.1 - 1.7e-82 277.3 0.0 2e-82 277.1 0.0 1.0 1 0 0 1 1 1 1 Streptococcal 67 kDa myosin-cross-reactive antigen like family NAD_binding_8 PF13450.1 EPS31202.1 - 0.16 12.0 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Cupin_8 PF13621.1 EPS31203.1 - 9.5e-10 38.3 0.0 2.4e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EPS31203.1 - 4.6e-09 36.5 0.1 5.4e-08 33.0 0.0 2.6 1 1 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 EPS31203.1 - 5.9e-09 35.4 5.0 5.9e-09 35.4 3.4 2.6 3 0 0 3 3 3 1 PHD-finger PHD_2 PF13831.1 EPS31203.1 - 0.023 13.9 3.3 0.035 13.4 1.1 2.3 2 0 0 2 2 2 0 PHD-finger DUF1423 PF07227.6 EPS31203.1 - 0.1 11.2 5.4 0.18 10.4 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) Zn_clus PF00172.13 EPS31203.1 - 7.7 6.5 30.9 0.34 10.8 4.2 3.5 3 1 0 3 3 3 0 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.17 EPS31205.1 - 6.2e-19 67.4 0.2 1.1e-18 66.5 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS31205.1 - 4.6e-13 48.9 0.0 7.4e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS31205.1 - 5.1e-10 39.0 0.1 7.9e-10 38.4 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3661 PF12400.3 EPS31206.1 - 9.1e-42 142.1 3.6 1.3e-41 141.6 2.5 1.2 1 0 0 1 1 1 1 Vaculolar membrane protein WD40 PF00400.27 EPS31208.1 - 1.1e-05 25.1 0.5 4.9 7.1 0.0 5.2 6 0 0 6 6 6 3 WD domain, G-beta repeat DUF946 PF06101.6 EPS31209.1 - 8.1e-12 43.9 0.6 1.5e-11 43.0 0.4 1.4 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) DUF2220 PF09983.4 EPS31209.1 - 0.15 11.2 0.4 0.26 10.4 0.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) Spt5_N PF11942.3 EPS31209.1 - 0.2 12.3 3.3 0.42 11.2 2.3 1.5 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal ELK PF03789.8 EPS31209.1 - 1.6 8.6 3.6 2.8 7.8 2.5 1.4 1 0 0 1 1 1 0 ELK domain TFIIIC_sub6 PF10419.4 EPS31211.1 - 8.4e-15 53.9 0.1 1.8e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 TFIIIC subunit Mito_fiss_reg PF05308.6 EPS31212.1 - 0.14 11.4 2.3 0.15 11.4 1.6 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator ELFV_dehydrog PF00208.16 EPS31216.1 - 3.4e-61 206.9 0.0 5.3e-61 206.2 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 EPS31216.1 - 4e-19 67.6 0.0 3.1e-14 51.4 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 EPS31216.1 - 0.0022 17.6 0.0 0.0059 16.1 0.0 1.7 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DUF2204 PF09970.4 EPS31217.1 - 0.00011 21.7 0.0 0.00017 21.0 0.0 1.3 1 1 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF2204) Glycos_transf_1 PF00534.15 EPS31217.1 - 0.025 13.9 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferases group 1 PolyA_pol PF01743.15 EPS31217.1 - 0.071 13.3 0.1 0.22 11.7 0.0 1.8 2 0 0 2 2 2 0 Poly A polymerase head domain Metallophos PF00149.23 EPS31218.1 - 6.1e-12 45.3 1.9 1.4e-11 44.2 1.3 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EPS31218.1 - 3.8e-08 33.3 0.0 7.7e-08 32.3 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MFS_1 PF07690.11 EPS31221.1 - 2.5e-22 79.1 26.1 5.4e-22 77.9 11.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS31221.1 - 1.9e-13 49.7 20.4 3.4e-12 45.6 14.2 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EPS31221.1 - 0.0019 16.4 2.9 0.0032 15.7 2.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PhyH PF05721.8 EPS31222.1 - 1.5e-07 31.7 0.1 3.3e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 EPS31222.1 - 9.9e-05 20.9 0.0 0.2 10.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1479) DHODB_Fe-S_bind PF10418.4 EPS31223.1 - 0.7 9.4 5.8 1.3 8.6 4.1 1.4 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Peptidase_S15 PF02129.13 EPS31224.1 - 1.1e-41 143.0 1.2 3.8e-40 138.0 0.1 2.1 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 EPS31224.1 - 4.4e-27 95.4 0.0 6.2e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 EPS31224.1 - 5.2e-08 33.0 0.0 8.7e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPS31224.1 - 0.00039 20.2 0.0 0.00077 19.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EPS31224.1 - 0.0061 15.8 0.3 0.0061 15.8 0.2 2.2 3 1 0 3 3 3 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 EPS31224.1 - 0.056 13.3 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase AXE1 PF05448.7 EPS31224.1 - 0.16 10.4 0.4 3.5 6.0 0.0 2.6 2 1 1 3 3 3 0 Acetyl xylan esterase (AXE1) Fungal_trans PF04082.13 EPS31225.1 - 6.6e-21 74.3 0.1 9.1e-20 70.6 0.1 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS31225.1 - 5.2e-09 35.8 12.3 8.7e-09 35.1 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tub_2 PF04525.7 EPS31226.1 - 4.6e-05 22.8 0.1 0.012 15.0 0.0 2.3 2 0 0 2 2 2 2 Tubby C 2 DUF1183 PF06682.7 EPS31226.1 - 0.4 10.2 6.1 0.066 12.8 0.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) DUF2930 PF11152.3 EPS31227.1 - 0.021 13.9 0.0 0.021 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2930) DUF1212 PF06738.7 EPS31228.1 - 1.8e-53 180.9 11.4 1.3e-45 155.2 0.8 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EPS31228.1 - 6.6e-28 97.2 8.8 6.6e-28 97.2 6.1 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3815) DUF2934 PF11154.3 EPS31228.1 - 0.028 13.7 0.1 0.052 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2934) DUF3720 PF12517.3 EPS31228.1 - 0.3 11.7 17.8 0.83 10.3 5.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3720) Sugar_tr PF00083.19 EPS31229.1 - 6.8e-70 235.8 24.8 7.8e-70 235.6 17.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS31229.1 - 3.1e-13 49.1 44.5 1.8e-07 30.2 13.6 2.8 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 EPS31229.1 - 0.0026 16.2 8.2 0.0026 16.2 5.7 2.7 3 0 0 3 3 3 2 MFS/sugar transport protein PPR_3 PF13812.1 EPS31230.1 - 3.6e-10 39.3 0.7 0.037 14.3 0.0 6.1 6 0 0 6 6 6 2 Pentatricopeptide repeat domain PPR_2 PF13041.1 EPS31230.1 - 1.1e-05 25.3 0.0 4.7 7.2 0.0 5.6 5 1 2 7 7 7 2 PPR repeat family PPR PF01535.15 EPS31230.1 - 0.0014 18.4 0.5 17 5.6 0.1 5.0 4 0 0 4 4 4 1 PPR repeat Glyco_hydro_67C PF07477.7 EPS31230.1 - 0.0096 15.3 0.2 0.046 13.1 0.0 2.2 2 1 0 2 2 2 1 Glycosyl hydrolase family 67 C-terminus TPR_14 PF13428.1 EPS31230.1 - 0.06 14.0 0.0 53 4.8 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Orn_Arg_deC_N PF02784.11 EPS31230.1 - 0.097 11.8 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Ribosomal_S18 PF01084.15 EPS31231.1 - 1.2e-13 50.7 0.0 2.6e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S18 VARLMGL PF14383.1 EPS31231.1 - 0.078 12.1 0.4 0.16 11.1 0.3 1.5 1 0 0 1 1 1 0 DUF761-associated sequence motif DUF963 PF06131.6 EPS31232.1 - 7.2e-08 31.5 21.2 7.2e-08 31.5 14.7 7.5 6 1 2 8 8 8 2 Schizosaccharomyces pombe repeat of unknown function (DUF963) PAN_1 PF00024.21 EPS31232.1 - 9.5e-06 25.2 0.5 4.4e-05 23.1 0.4 2.2 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.1 EPS31232.1 - 0.025 14.2 0.5 0.075 12.7 0.3 1.8 1 0 0 1 1 1 0 PAN domain WD40 PF00400.27 EPS31233.1 - 7e-52 171.5 22.6 1.9e-09 37.0 0.5 10.7 10 0 0 10 10 10 9 WD domain, G-beta repeat eIF2A PF08662.6 EPS31233.1 - 8.6e-08 32.1 0.3 0.079 12.6 0.0 4.2 3 3 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A IRF PF00605.12 EPS31233.1 - 0.089 12.5 1.1 12 5.7 0.1 2.9 2 1 1 3 3 3 0 Interferon regulatory factor transcription factor FUSC_2 PF13515.1 EPS31234.1 - 4.3e-29 101.0 8.2 4.3e-29 101.0 5.7 2.9 2 1 1 3 3 3 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 EPS31234.1 - 8.7e-06 25.5 2.8 1.2e-05 25.0 0.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) ALMT PF11744.3 EPS31234.1 - 3.8e-05 22.5 20.7 0.065 11.8 0.0 4.6 4 1 0 4 4 4 2 Aluminium activated malate transporter FUSC PF04632.7 EPS31234.1 - 3.5 5.9 31.1 0.27 9.6 0.0 4.4 3 1 0 3 3 3 0 Fusaric acid resistance protein family SAGA-Tad1 PF12767.2 EPS31235.1 - 3.3e-59 200.6 0.0 4.4e-59 200.1 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit PRP1_N PF06424.7 EPS31237.1 - 7.4e-54 181.6 7.3 2.2e-53 180.1 5.1 1.9 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 EPS31237.1 - 4.9e-31 104.3 35.5 0.0013 19.1 0.0 14.3 5 3 10 15 15 15 11 Tetratricopeptide repeat TPR_19 PF14559.1 EPS31237.1 - 2.8e-26 91.6 14.9 1.7e-06 28.2 0.2 9.5 6 2 3 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.1 EPS31237.1 - 6.5e-25 87.1 25.0 1.9e-05 25.2 0.6 8.6 7 1 2 9 9 9 5 Tetratricopeptide repeat TPR_11 PF13414.1 EPS31237.1 - 4.6e-13 48.6 11.4 0.00085 18.9 0.0 7.8 5 2 3 8 8 8 4 TPR repeat TPR_2 PF07719.12 EPS31237.1 - 5.2e-11 41.5 13.9 0.1 12.5 0.0 8.9 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_15 PF13429.1 EPS31237.1 - 1.3e-08 34.2 21.3 1.4e-05 24.3 4.9 5.2 4 2 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 EPS31237.1 - 1.1e-06 27.9 1.3 0.059 13.0 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EPS31237.1 - 1e-05 24.9 0.2 0.77 9.6 0.0 6.8 7 1 1 8 8 7 1 Tetratricopeptide repeat TPR_17 PF13431.1 EPS31237.1 - 6.3e-05 22.8 4.9 32 5.0 0.0 7.9 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_12 PF13424.1 EPS31237.1 - 0.00029 20.7 6.8 2 8.4 0.0 6.3 3 1 2 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 EPS31237.1 - 0.0019 17.8 3.4 12 6.0 0.0 6.1 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_21 PF09976.4 EPS31237.1 - 0.011 15.6 20.8 0.063 13.2 2.0 4.7 3 1 1 5 5 5 0 Tetratricopeptide repeat DUF3808 PF10300.4 EPS31237.1 - 0.037 12.5 1.3 3.3 6.1 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3808) DUF501 PF04417.7 EPS31237.1 - 1.2 9.0 7.2 1.2 8.9 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF501) TPR_6 PF13174.1 EPS31237.1 - 4.5 7.9 18.6 1e+02 3.6 0.0 8.9 10 0 0 10 10 10 0 Tetratricopeptide repeat RrnaAD PF00398.15 EPS31238.1 - 1e-57 195.1 0.0 1.4e-57 194.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EPS31238.1 - 5.3e-11 42.5 0.0 9.7e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS31238.1 - 9.5e-07 29.3 0.0 1.7e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPS31238.1 - 7e-06 25.7 0.0 1.3e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPS31238.1 - 7.2e-06 26.4 0.0 1.6e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPS31238.1 - 0.00019 20.8 0.0 0.00031 20.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EPS31238.1 - 0.00023 21.5 0.0 0.00051 20.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPS31238.1 - 0.00024 20.8 0.0 0.00045 19.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EPS31238.1 - 0.00099 18.6 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.13 EPS31238.1 - 0.0026 17.0 0.0 0.0047 16.1 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_25 PF13649.1 EPS31238.1 - 0.0044 17.3 0.0 0.0089 16.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EPS31238.1 - 0.0046 16.5 0.0 0.0079 15.8 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein CMAS PF02353.15 EPS31238.1 - 0.0063 15.6 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_3 PF01596.12 EPS31238.1 - 0.054 12.5 0.1 0.13 11.2 0.1 1.6 1 1 0 1 1 1 0 O-methyltransferase RabGAP-TBC PF00566.13 EPS31239.1 - 3e-49 167.3 0.0 9.7e-49 165.7 0.0 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain CAP_N PF01213.14 EPS31240.1 - 0.92 8.7 3.9 1 8.5 2.7 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal RRM_1 PF00076.17 EPS31241.1 - 5.5e-38 128.4 0.3 1e-17 63.5 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS31241.1 - 2.5e-30 104.2 0.1 4.3e-14 52.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS31241.1 - 1.1e-14 53.9 0.0 1.5e-06 27.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EPS31241.1 - 0.0026 17.5 0.1 2.6 7.9 0.0 2.7 2 0 0 2 2 2 2 RNA binding motif Pkinase PF00069.20 EPS31242.1 - 0.0028 16.8 0.0 0.0052 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain TRP PF06011.7 EPS31243.1 - 1.8e-129 432.1 12.4 2.2e-129 431.8 8.6 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EPS31243.1 - 7.6e-38 129.7 2.7 1.2e-37 129.0 1.9 1.3 1 0 0 1 1 1 1 ML-like domain CRT-like PF08627.5 EPS31243.1 - 2.3 8.1 7.5 0.098 12.5 0.5 2.1 2 0 0 2 2 2 0 CRT-like SCIMP PF15050.1 EPS31243.1 - 7 6.5 12.7 0.062 13.1 0.8 3.0 3 0 0 3 3 3 0 SCIMP protein Hep_59 PF07052.6 EPS31245.1 - 1.1e-17 64.3 0.0 1.1e-17 64.3 0.0 3.4 3 1 1 4 4 4 1 Hepatocellular carcinoma-associated antigen 59 Actin PF00022.14 EPS31246.1 - 3.8e-146 486.5 0.0 4.3e-146 486.3 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EPS31246.1 - 0.0031 16.1 0.0 3.5 6.1 0.0 3.0 3 0 0 3 3 3 2 MreB/Mbl protein MFS_1 PF07690.11 EPS31247.1 - 1.9e-33 115.6 49.7 6e-33 114.0 33.9 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Dabb PF07876.7 EPS31248.1 - 9.3e-08 32.4 0.0 1.3e-07 31.9 0.0 1.3 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain Fungal_trans PF04082.13 EPS31249.1 - 2e-10 40.0 1.0 1.4e-09 37.2 0.4 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 EPS31249.1 - 7.9e-09 35.3 14.1 3.3e-06 27.1 0.8 3.9 3 1 0 3 3 3 2 Zinc-finger double domain Zn_clus PF00172.13 EPS31249.1 - 7.4e-08 32.1 7.6 1.8e-07 30.9 5.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.21 EPS31249.1 - 3.1e-07 30.3 15.7 0.0009 19.4 1.2 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPS31249.1 - 2.1e-06 27.6 20.7 0.0002 21.4 1.9 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger Innate_immun PF12782.2 EPS31249.1 - 0.27 10.4 2.7 0.38 9.9 1.9 1.1 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family zf-Di19 PF05605.7 EPS31249.1 - 0.99 9.5 6.6 0.14 12.3 1.3 2.1 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 EPS31249.1 - 1 9.5 5.9 0.17 12.0 0.5 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding AMP-binding PF00501.23 EPS31251.1 - 8e-169 561.4 0.0 7e-91 304.6 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EPS31251.1 - 5.2e-76 255.3 9.1 2.4e-31 108.7 0.5 4.5 4 0 0 4 4 4 4 Condensation domain AMP-binding_C PF13193.1 EPS31251.1 - 2.5e-13 50.7 0.6 1.2e-05 26.1 0.1 2.7 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain PP-binding PF00550.20 EPS31251.1 - 1.6e-12 47.4 0.0 2.3e-05 24.5 0.0 3.1 2 0 0 2 2 2 2 Phosphopantetheine attachment site Ku_PK_bind PF08785.6 EPS31251.1 - 0.085 12.7 0.3 0.44 10.4 0.1 2.3 2 0 0 2 2 2 0 Ku C terminal domain like Peptidase_C74 PF12387.3 EPS31254.1 - 0.092 11.9 0.6 0.13 11.3 0.4 1.2 1 0 0 1 1 1 0 Pestivirus NS2 peptidase zf-C4_Topoisom PF01396.14 EPS31255.1 - 0.0049 16.3 0.0 0.013 14.9 0.0 1.7 1 0 0 1 1 1 1 Topoisomerase DNA binding C4 zinc finger Fungal_trans PF04082.13 EPS31258.1 - 2.1e-10 39.9 0.0 4.4e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain UDG PF03167.14 EPS31259.1 - 6.6e-24 84.1 0.1 1.2e-23 83.2 0.0 1.5 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Thioredoxin PF00085.15 EPS31260.1 - 4e-66 219.2 5.5 9.6e-33 111.9 0.1 4.2 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.1 EPS31260.1 - 8.2e-52 175.6 6.3 2.6e-39 134.9 0.4 3.6 3 2 1 4 4 4 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EPS31260.1 - 2.1e-10 40.7 5.4 0.00085 19.4 0.3 4.4 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EPS31260.1 - 3.1e-10 39.9 0.4 0.00022 21.1 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin-like Calsequestrin PF01216.12 EPS31260.1 - 7.2e-10 38.1 3.6 1.1e-08 34.2 0.2 2.4 1 1 1 2 2 2 2 Calsequestrin Thioredoxin_8 PF13905.1 EPS31260.1 - 9.1e-10 38.5 0.3 0.0024 17.9 0.0 4.0 4 1 1 5 5 5 2 Thioredoxin-like Redoxin PF08534.5 EPS31260.1 - 7.2e-07 28.8 1.4 0.062 12.8 0.0 3.4 3 0 0 3 3 3 2 Redoxin AhpC-TSA PF00578.16 EPS31260.1 - 1.3e-06 28.0 1.1 0.0046 16.6 0.0 3.0 3 0 0 3 3 3 2 AhpC/TSA family ERp29_N PF07912.8 EPS31260.1 - 4.3e-05 23.4 0.4 0.22 11.4 0.0 3.9 4 0 0 4 4 4 2 ERp29, N-terminal domain Thioredoxin_4 PF13462.1 EPS31260.1 - 0.0061 16.5 7.3 0.068 13.1 0.0 4.0 4 1 0 4 4 4 1 Thioredoxin Mu-like_Com PF10122.4 EPS31260.1 - 0.27 10.3 0.7 17 4.5 0.0 2.4 2 0 0 2 2 2 0 Mu-like prophage protein Com ATG22 PF11700.3 EPS31262.1 - 2.7e-207 688.9 15.0 3.1e-207 688.7 10.4 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EPS31262.1 - 1e-07 31.0 18.2 1e-07 31.0 12.6 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily Pkinase PF00069.20 EPS31263.1 - 3.2e-10 39.5 0.0 4.2e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EPS31263.1 - 1.3e-06 28.3 0.0 1.8e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EPS31263.1 - 2e-05 23.7 0.0 2.7e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EPS31263.1 - 0.00035 19.6 0.0 0.00052 19.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EPS31263.1 - 0.00089 18.6 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 EPS31263.1 - 0.0025 17.4 0.0 0.0037 16.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.1 EPS31263.1 - 0.011 14.7 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Med14 PF08638.6 EPS31264.1 - 3.5e-70 235.2 0.0 6.2e-70 234.4 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit MED14 DNA_pol_E_B PF04042.11 EPS31265.1 - 2.7e-49 167.2 0.1 3.7e-49 166.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B SLAIN PF15301.1 EPS31265.1 - 0.27 10.3 3.6 1.2 8.2 0.6 2.5 2 0 0 2 2 2 0 SLAIN motif-containing family SHNi-TPR PF10516.4 EPS31266.1 - 3.5e-15 54.9 1.2 6.7e-15 54.0 0.1 2.2 2 0 0 2 2 2 1 SHNi-TPR TPR_11 PF13414.1 EPS31266.1 - 1e-06 28.2 4.6 0.025 14.2 0.8 2.8 3 0 0 3 3 3 2 TPR repeat TPR_12 PF13424.1 EPS31266.1 - 0.00066 19.5 11.0 0.045 13.6 0.0 3.1 4 0 0 4 4 4 2 Tetratricopeptide repeat CCDC-167 PF15188.1 EPS31266.1 - 0.63 10.0 5.9 1.9 8.4 4.1 1.8 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Yippee-Mis18 PF03226.9 EPS31267.1 - 6.5e-21 74.1 0.4 1.1e-20 73.4 0.3 1.4 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.3 EPS31267.1 - 0.077 12.8 0.2 0.55 10.1 0.0 2.0 2 0 0 2 2 2 0 C-terminal domain of RIG-I Transp_Tc5_C PF04236.10 EPS31267.1 - 0.12 12.6 2.5 0.12 12.6 0.5 1.8 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain Ribosomal_S27e PF01667.12 EPS31267.1 - 0.75 9.3 4.4 3.6 7.1 0.7 2.3 2 0 0 2 2 2 0 Ribosomal protein S27 Zip PF02535.17 EPS31267.1 - 3.2 6.6 5.6 4.9 6.0 3.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter ODC_AZ PF02100.12 EPS31268.1 - 8e-26 89.6 0.0 1.2e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme DWNN PF08783.6 EPS31269.1 - 1.3e-31 108.2 0.3 3.3e-31 107.0 0.0 1.8 2 0 0 2 2 2 1 DWNN domain zf-CCHC_2 PF13696.1 EPS31269.1 - 7.6e-06 25.3 7.3 1.9e-05 24.0 5.1 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EPS31269.1 - 0.0086 15.9 1.2 0.02 14.8 0.8 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-Nse PF11789.3 EPS31269.1 - 0.51 9.9 4.3 1 8.8 3.0 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.1 EPS31269.1 - 3.1 7.6 11.2 0.16 11.6 3.5 2.0 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.20 EPS31269.1 - 3.1 7.5 8.2 6.8 6.4 5.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EPS31269.1 - 5.8 6.8 9.6 14 5.6 6.7 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING His_biosynth PF00977.16 EPS31271.1 - 8.5e-47 159.3 0.5 2.1e-46 158.0 0.3 1.7 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 EPS31271.1 - 8.8e-28 97.0 0.0 1.3e-27 96.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 EPS31271.1 - 2.2e-10 40.4 0.0 8.8e-09 35.2 0.0 2.3 2 0 0 2 2 2 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 EPS31271.1 - 9.5e-09 35.0 0.0 2.7e-08 33.5 0.0 1.7 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.8 EPS31271.1 - 0.00064 19.2 0.0 0.0018 17.7 0.0 1.8 1 1 0 1 1 1 1 Peptidase C26 UPF0180 PF03698.8 EPS31271.1 - 0.057 13.2 0.2 4.1 7.3 0.0 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0180) dCMP_cyt_deam_1 PF00383.17 EPS31272.1 - 5.1e-27 93.4 0.6 8.5e-27 92.7 0.4 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_18 PF13238.1 EPS31272.1 - 0.0045 17.3 0.0 0.012 15.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain CoaE PF01121.15 EPS31272.1 - 0.014 14.8 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 Dephospho-CoA kinase ThiF PF00899.16 EPS31273.1 - 6e-29 100.6 0.0 1.1e-28 99.7 0.0 1.5 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 EPS31273.1 - 0.0011 19.1 0.0 0.0028 17.7 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 EPS31273.1 - 0.056 12.5 0.0 0.36 9.9 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Flagellin_C PF00700.16 EPS31273.1 - 0.067 13.3 0.4 0.14 12.3 0.2 1.4 1 0 0 1 1 1 0 Bacterial flagellin C-terminal helical region FtsJ PF01728.14 EPS31274.1 - 4.5e-59 199.4 0.0 5.3e-59 199.2 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 EPS31274.1 - 0.0014 18.3 0.0 0.0033 17.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS31274.1 - 0.035 14.6 0.0 0.077 13.5 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EPS31274.1 - 0.084 12.4 0.0 8.1 6.0 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain OST3_OST6 PF04756.8 EPS31276.1 - 4.7e-21 75.0 4.7 7.8e-21 74.2 3.3 1.2 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 EPS31276.1 - 0.0028 17.3 0.0 0.0064 16.1 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin DUF2649 PF10854.3 EPS31276.1 - 0.046 13.8 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2649) DUF805 PF05656.9 EPS31276.1 - 1.3 8.8 7.2 5.7 6.8 5.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF805) Rft-1 PF04506.8 EPS31277.1 - 2.6e-101 339.6 8.0 3.2e-101 339.4 5.5 1.0 1 0 0 1 1 1 1 Rft protein Polysacc_synt PF01943.12 EPS31277.1 - 1.2e-05 24.7 3.0 1.2e-05 24.7 2.1 3.0 3 0 0 3 3 3 2 Polysaccharide biosynthesis protein ATP-synt_J PF04911.7 EPS31277.1 - 0.61 9.5 2.9 1.7 8.1 0.0 2.8 3 0 0 3 3 3 0 ATP synthase j chain DEAD PF00270.24 EPS31278.1 - 3.1e-45 153.6 0.0 2.5e-44 150.7 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPS31278.1 - 9.5e-26 89.4 0.1 2.4e-25 88.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPS31278.1 - 4.5e-06 26.6 0.3 5.1e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EPS31278.1 - 5.6e-06 25.6 9.9 0.0018 17.3 0.0 2.5 2 0 0 2 2 2 2 U3-containing 90S pre-ribosomal complex subunit Peptidase_S49_N PF08496.5 EPS31278.1 - 1.1 9.0 5.2 2.1 8.1 3.6 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF1253 PF06862.7 EPS31278.1 - 2.1 6.6 6.2 1.5 7.1 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1253) DDHD PF02862.12 EPS31278.1 - 8.5 6.1 7.5 19 4.9 5.2 1.5 1 0 0 1 1 1 0 DDHD domain Rep_fac-A_C PF08646.5 EPS31279.1 - 2.2e-52 176.6 1.8 2.9e-50 169.7 0.8 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 EPS31279.1 - 1.1e-22 79.7 0.0 2.6e-22 78.5 0.0 1.7 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 EPS31279.1 - 2.2e-13 49.8 0.0 1.9e-08 34.0 0.0 3.6 3 0 0 3 3 3 2 OB-fold nucleic acid binding domain UCH PF00443.24 EPS31280.1 - 1.2e-45 155.7 0.0 2.5e-45 154.6 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EPS31280.1 - 1.5e-24 85.9 17.2 2.3e-19 69.2 2.0 3.2 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 EPS31280.1 - 8.5e-21 73.1 0.0 4.9e-09 35.7 0.0 2.7 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.1 EPS31280.1 - 3.6e-20 72.5 0.0 3.7e-19 69.2 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.1 EPS31280.1 - 0.0026 17.2 0.0 0.0065 15.9 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain TerY-C PF15616.1 EPS31280.1 - 0.41 10.5 10.8 0.94 9.4 0.2 3.3 2 1 1 3 3 3 0 TerY-C metal binding domain SH3BGR PF04908.10 EPS31281.1 - 0.011 15.6 0.7 0.019 14.9 0.5 1.3 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein Uds1 PF15456.1 EPS31281.1 - 0.14 12.1 2.2 0.25 11.3 1.5 1.4 1 0 0 1 1 1 0 Up-regulated During Septation Ax_dynein_light PF10211.4 EPS31281.1 - 2.9 7.7 9.1 0.37 10.5 3.6 1.5 2 0 0 2 2 2 0 Axonemal dynein light chain FKBP_N PF01346.13 EPS31281.1 - 3.5 7.7 5.7 6.5 6.8 4.0 1.4 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Ank PF00023.25 EPS31282.1 - 8.9e-18 63.1 0.0 0.00065 19.3 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 EPS31282.1 - 1.8e-17 63.4 0.0 1.5e-08 34.8 0.0 2.4 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EPS31282.1 - 3.7e-13 49.2 0.2 8.2e-07 29.0 0.1 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPS31282.1 - 5.4e-13 47.8 0.0 0.0052 16.9 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.1 EPS31282.1 - 4.2e-08 33.4 0.1 0.14 12.7 0.0 3.8 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Zn_clus PF00172.13 EPS31283.1 - 3.2e-07 30.1 7.1 3.2e-07 30.1 4.9 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EPS31283.1 - 7.4e-05 21.5 0.1 0.00015 20.5 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF305 PF03713.8 EPS31283.1 - 0.17 11.6 0.5 0.99 9.2 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF305) RTA1 PF04479.8 EPS31284.1 - 2e-32 112.5 6.0 7.6e-31 107.3 4.1 2.0 1 1 0 1 1 1 1 RTA1 like protein HCO3_cotransp PF00955.16 EPS31285.1 - 2.5e-54 184.8 13.7 5.8e-34 117.6 3.6 2.1 1 1 1 2 2 2 2 HCO3- transporter family SET PF00856.23 EPS31287.1 - 7.6e-11 42.5 0.2 5.3e-10 39.8 0.0 2.2 2 0 0 2 2 2 1 SET domain TPR_12 PF13424.1 EPS31291.1 - 4.1e-81 266.9 0.6 5.5e-17 61.4 0.0 4.7 2 1 4 6 6 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 EPS31291.1 - 2.5e-78 256.0 0.3 8.1e-12 44.6 0.0 7.4 7 0 0 7 7 7 6 Tetratricopeptide repeat Ank PF00023.25 EPS31291.1 - 4.4e-39 130.3 3.0 7.3e-07 28.6 0.0 6.0 6 0 0 6 6 6 5 Ankyrin repeat Ank_2 PF12796.2 EPS31291.1 - 2.4e-35 120.7 0.0 5.8e-18 65.0 0.0 3.9 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EPS31291.1 - 5.4e-28 96.3 0.4 1.5e-05 25.0 0.0 5.4 2 2 3 5 5 5 5 Ankyrin repeats (many copies) TPR_7 PF13176.1 EPS31291.1 - 1.1e-26 90.4 1.4 0.0014 18.2 0.0 6.3 6 0 0 6 6 6 6 Tetratricopeptide repeat Ank_3 PF13606.1 EPS31291.1 - 3.4e-25 85.5 0.0 0.0019 18.2 0.0 6.4 6 0 0 6 6 5 5 Ankyrin repeat TPR_2 PF07719.12 EPS31291.1 - 1.5e-22 77.5 0.5 0.005 16.6 0.0 6.4 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_17 PF13431.1 EPS31291.1 - 3e-22 76.9 2.8 0.054 13.7 0.0 6.5 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.23 EPS31291.1 - 1.1e-21 75.4 2.4 0.05 13.2 0.0 6.4 6 0 0 6 6 6 6 Tetratricopeptide repeat TPR_4 PF07721.9 EPS31291.1 - 1.6e-20 71.3 0.0 0.07 13.5 0.0 6.6 6 0 0 6 6 6 6 Tetratricopeptide repeat Ank_4 PF13637.1 EPS31291.1 - 7.9e-20 70.8 0.1 1.4e-06 28.6 0.0 5.0 2 2 3 5 5 5 4 Ankyrin repeats (many copies) TPR_19 PF14559.1 EPS31291.1 - 5.2e-18 65.1 0.5 0.38 11.1 0.0 6.3 2 2 4 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.1 EPS31291.1 - 2.7e-17 62.1 1.0 0.00015 21.3 0.0 5.2 2 2 2 5 5 5 5 TPR repeat TPR_16 PF13432.1 EPS31291.1 - 6.4e-15 55.3 0.0 0.00037 21.0 0.0 5.3 2 2 4 6 6 6 4 Tetratricopeptide repeat Apc3 PF12895.2 EPS31291.1 - 3.3e-13 49.5 0.0 0.0013 18.8 0.0 4.7 1 1 3 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.15 EPS31291.1 - 4.5e-12 45.0 3.6 1.8 8.7 0.0 6.5 6 0 0 6 6 6 3 PPR repeat PPR_3 PF13812.1 EPS31291.1 - 2.1e-11 43.1 4.0 3.2 8.2 0.0 7.1 7 0 0 7 7 6 1 Pentatricopeptide repeat domain TPR_8 PF13181.1 EPS31291.1 - 1.6e-10 39.9 3.2 2.7 8.0 0.0 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 EPS31291.1 - 3.9e-10 39.4 1.2 7.1 7.5 0.0 6.6 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_20 PF14561.1 EPS31291.1 - 3.8e-09 36.5 0.4 8.5 6.5 0.0 6.3 1 1 5 6 6 6 0 Tetratricopeptide repeat DUF814 PF05670.8 EPS31291.1 - 6.3e-09 35.6 0.9 1.7 8.5 0.0 5.3 2 1 3 5 5 5 2 Domain of unknown function (DUF814) TPR_6 PF13174.1 EPS31291.1 - 2.9e-08 33.6 10.5 0.39 11.2 0.0 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat Rapsyn_N PF10579.4 EPS31291.1 - 1.9e-06 27.5 0.8 0.051 13.3 0.1 4.5 2 1 2 4 4 4 1 Rapsyn N-terminal myristoylation and linker region DUF4074 PF13293.1 EPS31291.1 - 5.3e-06 26.5 2.1 11 6.3 0.0 6.5 7 0 0 7 7 7 0 Domain of unknown function (DUF4074) PPR_2 PF13041.1 EPS31291.1 - 1.2e-05 25.1 0.2 15 5.6 0.0 5.8 6 0 0 6 6 6 0 PPR repeat family BTAD PF03704.12 EPS31291.1 - 0.00048 20.4 1.0 4.6 7.5 0.0 4.1 2 2 2 4 4 4 1 Bacterial transcriptional activator domain DUF3366 PF11846.3 EPS31291.1 - 0.021 14.6 4.9 10 5.9 0.0 4.4 1 1 2 4 4 4 0 Domain of unknown function (DUF3366) TPR_3 PF07720.7 EPS31291.1 - 0.031 14.0 0.0 8.3 6.3 0.0 4.4 6 0 0 6 6 6 0 Tetratricopeptide repeat A2M PF00207.17 EPS31291.1 - 0.053 13.1 3.9 4.5 6.9 0.0 4.1 2 1 3 5 5 5 0 Alpha-2-macroglobulin family DUF3435 PF11917.3 EPS31294.1 - 4.3e-39 134.4 1.5 3.3e-17 62.3 0.0 3.0 1 1 2 3 3 3 3 Protein of unknown function (DUF3435) RVT_2 PF07727.9 EPS31296.1 - 1.2e-21 76.8 0.0 2.2e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EPS31297.1 - 1.3e-17 63.9 0.0 3.2e-17 62.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 EPS31297.1 - 0.0032 17.0 0.0 0.0081 15.7 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain UBN2_3 PF14244.1 EPS31297.1 - 0.0065 16.0 0.1 0.02 14.4 0.0 1.8 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.1 EPS31297.1 - 0.12 12.0 3.6 0.29 10.8 2.5 1.6 1 0 0 1 1 1 0 Zinc knuckle RAMP4 PF06624.7 EPS31298.1 - 5.3e-08 32.2 0.0 6.2e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 MarC PF01914.12 EPS31298.1 - 0.042 12.9 0.0 0.05 12.7 0.0 1.2 1 0 0 1 1 1 0 MarC family integral membrane protein Adaptin_N PF01602.15 EPS31299.1 - 1.3e-86 291.0 0.0 1.8e-85 287.2 0.0 2.1 1 1 0 1 1 1 1 Adaptin N terminal region HEAT PF02985.17 EPS31299.1 - 8.6e-07 28.5 2.4 0.083 13.0 0.0 5.1 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 EPS31299.1 - 3.9e-06 27.0 4.7 0.45 10.8 0.3 3.9 3 0 0 3 3 3 2 HEAT repeats Cnd1 PF12717.2 EPS31299.1 - 0.00025 20.9 0.7 0.42 10.4 0.1 2.6 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 EPS31299.1 - 0.16 12.5 7.5 2.1 8.9 0.1 4.9 4 1 1 5 5 5 0 HEAT-like repeat TPR_11 PF13414.1 EPS31300.1 - 3.6e-09 36.1 2.5 9.1e-07 28.4 0.1 4.1 3 1 2 5 5 5 2 TPR repeat TPR_17 PF13431.1 EPS31300.1 - 4.5e-07 29.5 0.0 0.23 11.7 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EPS31300.1 - 2.7e-06 27.6 9.1 0.00015 21.9 0.4 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EPS31300.1 - 8.1e-06 26.0 10.1 0.02 15.4 0.9 5.2 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EPS31300.1 - 5.8e-05 23.6 8.3 0.0031 18.1 1.1 4.1 2 1 3 5 5 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EPS31300.1 - 0.00012 21.5 0.3 0.09 12.5 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 EPS31300.1 - 0.00049 19.5 0.7 0.0098 15.4 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EPS31300.1 - 0.0014 18.3 6.3 0.033 14.0 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 EPS31300.1 - 0.022 14.6 2.3 0.07 12.9 0.4 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EPS31300.1 - 0.055 13.4 0.1 0.055 13.4 0.1 3.9 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EPS31300.1 - 0.21 12.1 3.3 64 4.3 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 EPS31300.1 - 0.22 11.4 2.4 2.8 7.9 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_11 PF13086.1 EPS31302.1 - 0.38 10.2 7.9 0.62 9.5 5.5 1.2 1 0 0 1 1 1 0 AAA domain SAPS PF04499.10 EPS31302.1 - 0.57 8.7 5.3 0.88 8.1 3.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Syja_N PF02383.13 EPS31303.1 - 1.3e-84 283.6 0.0 1.9e-84 283.1 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 EPS31303.1 - 1.4e-25 90.6 0.3 1.4e-25 90.6 0.2 1.7 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family TRAPP PF04051.11 EPS31303.1 - 0.16 11.4 0.0 0.32 10.4 0.0 1.4 1 0 0 1 1 1 0 Transport protein particle (TRAPP) component G-patch PF01585.18 EPS31304.1 - 4.8e-05 23.0 0.0 0.00054 19.6 0.0 2.4 1 1 0 1 1 1 1 G-patch domain CDC27 PF09507.5 EPS31304.1 - 0.016 14.4 31.0 0.02 14.1 21.5 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TFIIF_alpha PF05793.7 EPS31304.1 - 0.018 13.4 32.5 0.024 13.0 22.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) MIP-T3 PF10243.4 EPS31304.1 - 0.034 12.6 32.9 0.047 12.1 22.8 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Bud13 PF09736.4 EPS31304.1 - 0.04 14.1 16.2 0.077 13.2 11.3 1.6 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex DUF572 PF04502.8 EPS31304.1 - 0.1 11.7 25.3 0.15 11.2 17.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Macoilin PF09726.4 EPS31304.1 - 0.12 10.6 17.9 0.13 10.4 12.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Neur_chan_memb PF02932.11 EPS31304.1 - 0.3 10.9 10.1 0.48 10.2 7.0 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SAPS PF04499.10 EPS31304.1 - 0.49 8.9 10.9 0.66 8.5 7.5 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.2 EPS31304.1 - 0.56 7.8 16.9 0.65 7.6 11.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF966 PF06136.8 EPS31304.1 - 0.9 8.8 25.0 1.3 8.3 17.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) FLO_LFY PF01698.11 EPS31304.1 - 1.4 7.6 15.9 2.1 7.1 11.0 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein Ycf1 PF05758.7 EPS31304.1 - 1.5 6.4 15.2 1.9 6.0 10.5 1.1 1 0 0 1 1 1 0 Ycf1 Parvo_coat PF00740.13 EPS31304.1 - 1.8 7.4 5.6 2.3 7.0 3.9 1.1 1 0 0 1 1 1 0 Parvovirus coat protein VP2 FAM60A PF15396.1 EPS31304.1 - 1.8 8.2 18.2 3.1 7.4 12.6 1.3 1 0 0 1 1 1 0 Protein Family FAM60A DUF2201_N PF13203.1 EPS31304.1 - 2.6 7.1 16.2 3.9 6.5 11.2 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Presenilin PF01080.12 EPS31304.1 - 2.6 6.7 14.6 3.9 6.1 10.1 1.3 1 0 0 1 1 1 0 Presenilin BTV_NS2 PF04514.7 EPS31304.1 - 3.8 6.3 20.2 5.5 5.7 14.0 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Hex_IIIa PF02455.11 EPS31304.1 - 5.3 5.6 10.5 6.8 5.2 7.3 1.2 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Paramyxo_ncap PF00973.14 EPS31304.1 - 5.6 5.5 10.6 6.8 5.2 7.3 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein SR-25 PF10500.4 EPS31304.1 - 8.3 5.8 44.5 15 4.9 30.8 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DAGAT PF03982.8 EPS31305.1 - 2.1e-91 305.7 0.0 2.6e-91 305.3 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Rer1 PF03248.8 EPS31305.1 - 0.033 13.7 5.7 0.033 13.7 3.2 1.5 1 1 1 2 2 2 0 Rer1 family Kinesin PF00225.18 EPS31306.1 - 1.7e-96 322.8 0.0 3e-96 322.0 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF2205 PF10224.4 EPS31306.1 - 0.39 10.3 5.6 4.5 6.9 2.0 2.7 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) Pkinase PF00069.20 EPS31308.1 - 8.5e-64 215.1 0.0 1e-63 214.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS31308.1 - 1.3e-34 119.4 0.0 1.7e-34 119.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPS31308.1 - 0.0026 16.7 0.0 0.0086 15.0 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EPS31308.1 - 0.06 13.0 0.1 0.25 11.0 0.0 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family IGR PF09597.5 EPS31309.1 - 2.1e-22 78.7 0.1 3.4e-22 78.1 0.1 1.3 1 0 0 1 1 1 1 IGR protein motif Shadoo PF14999.1 EPS31309.1 - 0.11 12.3 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective p450 PF00067.17 EPS31310.1 - 2.2e-73 247.3 0.0 2.7e-73 247.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 EPS31312.1 - 1.8e-78 263.3 0.0 2.4e-78 262.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS31312.1 - 7.4e-37 126.8 0.0 1.1e-36 126.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EPS31312.1 - 7.2e-15 54.8 0.1 1.6e-14 53.7 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EPS31312.1 - 3.6e-11 42.5 0.0 1.5e-09 37.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EPS31312.1 - 0.00016 21.5 0.2 0.00043 20.0 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EPS31312.1 - 0.0076 15.3 0.0 0.015 14.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EPS31312.1 - 0.077 12.3 0.0 0.19 11.0 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pox_ser-thr_kin PF05445.6 EPS31312.1 - 0.091 11.5 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PI3_PI4_kinase PF00454.22 EPS31313.1 - 4.8e-35 121.1 0.0 2.2e-34 118.9 0.0 2.1 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EPS31313.1 - 1.1e-23 83.4 0.1 2.4e-23 82.2 0.1 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) LRR_6 PF13516.1 EPS31314.1 - 0.028 14.4 8.2 5.6 7.3 0.0 6.4 8 0 0 8 8 8 0 Leucine Rich repeat SNF2_N PF00176.18 EPS31315.1 - 1.8e-64 217.4 0.1 3e-64 216.6 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPS31315.1 - 9.5e-13 47.8 0.0 2.4e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 EPS31315.1 - 1.1e-06 28.2 6.9 1.1e-06 28.2 4.8 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPS31315.1 - 3.2e-05 23.8 6.6 3.2e-05 23.8 4.6 2.4 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPS31315.1 - 3.5e-05 23.3 6.9 3.5e-05 23.3 4.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPS31315.1 - 0.00049 19.8 7.6 0.00049 19.8 5.3 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EPS31315.1 - 0.002 17.7 7.8 0.002 17.7 5.4 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EPS31315.1 - 0.004 16.9 6.0 0.004 16.9 4.2 2.4 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EPS31315.1 - 0.013 15.1 1.6 0.013 15.1 1.1 2.4 2 0 0 2 2 2 0 RING-type zinc-finger Zn_Tnp_IS91 PF14319.1 EPS31315.1 - 0.92 9.0 15.6 0.06 12.8 1.9 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain Zn-ribbon_8 PF09723.5 EPS31315.1 - 1 9.3 15.3 0.049 13.5 1.3 2.8 2 0 0 2 2 2 0 Zinc ribbon domain C2 PF00168.25 EPS31316.1 - 8.7e-09 35.1 0.1 1.7e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 C2 domain ArfGap PF01412.13 EPS31319.1 - 1.3e-33 115.2 0.0 1.3e-33 115.2 0.0 2.6 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf PH PF00169.24 EPS31319.1 - 1.3e-12 47.8 0.1 3.7e-12 46.3 0.1 1.8 1 0 0 1 1 1 1 PH domain DUF963 PF06131.6 EPS31320.1 - 0.26 10.5 2.1 5.6 6.3 0.1 2.5 2 0 0 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) YTH PF04146.10 EPS31321.1 - 1.4e-56 189.9 0.0 2.1e-56 189.3 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain RRM_6 PF14259.1 EPS31321.1 - 9.3e-08 31.9 0.0 1.8e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPS31321.1 - 1.4e-07 31.0 0.0 2.5e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS31321.1 - 0.014 15.2 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Telomere_Sde2 PF13019.1 EPS31321.1 - 0.09 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Telomere stability and silencing Katanin_con80 PF13925.1 EPS31322.1 - 0.095 12.4 0.0 0.1 12.3 0.0 1.0 1 0 0 1 1 1 0 con80 domain of Katanin APH PF01636.18 EPS31325.1 - 2e-09 37.5 0.0 9e-08 32.1 0.0 2.0 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pirin PF02678.11 EPS31326.1 - 1.4e-32 111.7 0.1 3e-32 110.6 0.0 1.6 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 EPS31326.1 - 2.8e-25 88.4 0.0 2.1e-24 85.6 0.0 2.1 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 EPS31326.1 - 1.1e-05 24.7 3.1 5.7e-05 22.5 0.8 2.4 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.7 EPS31326.1 - 0.13 11.6 0.2 0.5 9.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF861) PRKCSH PF07915.8 EPS31327.1 - 1.8e-19 70.3 0.4 1.8e-19 70.3 0.3 2.4 3 0 0 3 3 3 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 EPS31327.1 - 0.014 14.8 0.1 0.045 13.2 0.1 1.9 1 1 0 1 1 1 0 Glucosidase II beta subunit-like protein SHD1 PF03983.7 EPS31328.1 - 3.5e-35 119.4 0.2 6.2e-35 118.6 0.2 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.23 EPS31328.1 - 3.9e-33 112.5 7.2 5e-12 45.0 0.0 4.3 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.1 EPS31328.1 - 4.3e-30 103.0 7.2 1.2e-11 44.0 0.2 4.0 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 EPS31328.1 - 7.7e-25 86.1 0.4 4.9e-08 32.3 0.0 4.4 4 0 0 4 4 4 4 Variant SH3 domain DUF1720 PF08226.6 EPS31328.1 - 4.9e-06 26.5 52.7 5.9e-05 23.0 19.5 6.6 1 1 3 4 4 4 2 Domain of unknown function (DUF1720) SH3_3 PF08239.6 EPS31328.1 - 8.7e-05 22.6 2.2 0.054 13.6 0.2 3.2 3 0 0 3 3 3 2 Bacterial SH3 domain SAM_1 PF00536.25 EPS31328.1 - 0.077 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF1989 PF09347.5 EPS31329.1 - 0.14 11.6 0.1 0.14 11.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1989) PAP2_3 PF14378.1 EPS31330.1 - 2.1e-21 76.3 10.3 1.4e-10 40.9 0.3 3.9 3 1 0 3 3 3 3 PAP2 superfamily PAP2 PF01569.16 EPS31330.1 - 0.0032 17.1 3.2 0.0077 15.9 1.1 2.3 1 1 1 2 2 2 1 PAP2 superfamily PWWP PF00855.12 EPS31331.1 - 4.1e-14 52.5 0.0 4.1e-14 52.5 0.0 3.2 3 1 0 3 3 3 1 PWWP domain SpoIIE PF07228.7 EPS31332.1 - 1.1e-11 44.8 0.1 2.5e-11 43.6 0.1 1.6 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EPS31332.1 - 9.1e-10 38.2 0.1 1.5e-09 37.5 0.1 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 EPS31332.1 - 4.8e-08 32.7 0.0 0.0017 17.7 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C WD40 PF00400.27 EPS31333.1 - 1.2e-45 151.7 18.2 8e-10 38.2 0.1 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 EPS31333.1 - 2.4e-13 49.0 5.9 2.4e-13 49.0 4.1 1.7 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like DUF4165 PF13752.1 EPS31333.1 - 0.02 14.6 0.0 0.18 11.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4165) eIF2A PF08662.6 EPS31333.1 - 0.071 12.8 0.0 2.2 7.9 0.0 2.9 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A HSCB_C PF07743.8 EPS31334.1 - 3.4e-20 72.2 0.2 4.1e-19 68.8 0.0 2.1 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 EPS31334.1 - 1.9e-11 43.4 0.0 3.7e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain SLAC1 PF03595.12 EPS31338.1 - 1.8e-83 279.9 38.6 2e-83 279.7 26.8 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel RTC_insert PF05189.8 EPS31339.1 - 1.9e-30 104.9 0.0 3.1e-30 104.2 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain RTC PF01137.16 EPS31339.1 - 2.1e-29 101.9 0.0 3e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase 3-HAO PF06052.7 EPS31340.1 - 5.1e-55 185.0 0.0 6.3e-55 184.7 0.0 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 EPS31340.1 - 0.00027 20.3 0.0 0.00044 19.6 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EPS31340.1 - 0.0024 17.3 0.1 0.0051 16.2 0.0 1.5 2 0 0 2 2 2 1 Cupin DZR PF12773.2 EPS31340.1 - 0.0035 17.1 1.1 0.0096 15.7 0.8 1.8 1 0 0 1 1 1 1 Double zinc ribbon AraC_binding PF02311.14 EPS31340.1 - 0.083 12.5 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 AraC-like ligand binding domain zf-ribbon_3 PF13248.1 EPS31340.1 - 0.088 12.0 0.8 3.1 7.1 0.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-B_box PF00643.19 EPS31340.1 - 0.17 11.7 2.2 12 5.8 0.1 3.1 3 0 0 3 3 3 0 B-box zinc finger FYVE PF01363.16 EPS31340.1 - 0.37 10.7 4.0 0.7 9.8 2.7 1.5 1 1 0 1 1 1 0 FYVE zinc finger zf-ISL3 PF14690.1 EPS31340.1 - 0.43 10.6 2.9 9.8 6.3 0.0 2.9 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Fer4_10 PF13237.1 EPS31340.1 - 1.6 8.5 5.5 2.1 8.1 0.3 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Nudix_N_2 PF14803.1 EPS31340.1 - 6.9 6.4 8.0 38 4.0 0.2 3.2 1 1 3 4 4 4 0 Nudix N-terminal CAP_GLY PF01302.20 EPS31342.1 - 5.8e-16 57.9 0.7 1.1e-15 57.0 0.5 1.5 1 0 0 1 1 1 1 CAP-Gly domain Med4 PF10018.4 EPS31342.1 - 3.6e-05 23.2 8.9 3.6e-05 23.2 6.2 4.0 2 1 2 4 4 4 1 Vitamin-D-receptor interacting Mediator subunit 4 AAA_13 PF13166.1 EPS31342.1 - 0.019 13.4 31.1 0.38 9.1 12.5 2.7 2 1 0 2 2 2 0 AAA domain Reo_sigmaC PF04582.7 EPS31342.1 - 0.44 9.6 11.4 0.34 10.0 1.2 2.8 1 1 1 3 3 3 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 EPS31342.1 - 0.73 10.1 15.6 2.2 8.6 0.5 3.8 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Tropomyosin PF00261.15 EPS31342.1 - 0.81 8.7 46.6 0.073 12.1 2.8 3.3 2 1 1 3 3 3 0 Tropomyosin SlyX PF04102.7 EPS31342.1 - 0.96 9.8 31.4 0.69 10.3 4.6 4.0 3 0 0 3 3 3 0 SlyX APG6 PF04111.7 EPS31342.1 - 2.3 7.2 46.8 0.046 12.7 7.0 3.1 1 1 2 3 3 3 0 Autophagy protein Apg6 TMF_DNA_bd PF12329.3 EPS31342.1 - 2.5 7.9 46.2 2.6 7.9 3.6 5.6 5 1 1 6 6 6 0 TATA element modulatory factor 1 DNA binding Pox_A_type_inc PF04508.7 EPS31342.1 - 2.8 7.9 22.3 1.2 9.0 2.5 5.0 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat YPEB PF14620.1 EPS31342.1 - 3.3 6.6 24.8 0.66 8.9 3.4 2.9 1 1 2 3 3 3 0 YpeB sporulation Cauli_AT PF03233.8 EPS31342.1 - 7.5 6.2 16.5 8.5 6.0 1.3 3.4 2 1 1 3 3 3 0 Aphid transmission protein Fez1 PF06818.10 EPS31342.1 - 8.1 6.4 40.8 1 9.3 1.3 3.8 2 1 2 4 4 4 0 Fez1 Pkinase PF00069.20 EPS31343.1 - 4.7e-39 134.1 0.0 2.1e-22 79.5 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPS31343.1 - 3.5e-14 52.4 0.0 2.6e-12 46.3 0.0 2.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPS31343.1 - 0.0001 22.1 0.0 0.00022 21.0 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EPS31343.1 - 0.0024 16.8 0.0 1.6 7.6 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Sulfolobus_pRN PF05584.6 EPS31344.1 - 0.074 13.0 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Sulfolobus plasmid regulatory protein Beta-Casp PF10996.3 EPS31348.1 - 0.041 13.8 2.5 1.3 8.9 0.0 2.9 3 1 0 3 3 3 0 Beta-Casp domain CVNH PF08881.5 EPS31348.1 - 0.4 10.9 2.2 2 8.7 1.3 2.6 2 1 0 2 2 2 0 CVNH domain SBP_bac_7 PF03480.8 EPS31348.1 - 0.81 8.7 4.4 3.8 6.5 0.5 2.7 2 1 1 3 3 3 0 Bacterial extracellular solute-binding protein, family 7 Med31 PF05669.7 EPS31349.1 - 0.063 13.0 0.0 0.71 9.6 0.0 2.1 2 0 0 2 2 2 0 SOH1 MFS_1 PF07690.11 EPS31350.1 - 3.1e-18 65.6 32.0 1.6e-15 56.6 17.0 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_43 PF04616.9 EPS31351.1 - 3.5e-25 88.6 3.9 2.3e-16 59.7 0.7 2.5 2 1 0 2 2 2 2 Glycosyl hydrolases family 43 Acetyltransf_3 PF13302.1 EPS31352.1 - 0.052 13.7 0.2 0.077 13.1 0.1 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Peptidase_S9 PF00326.16 EPS31353.1 - 5.8e-52 176.0 0.1 1.2e-51 174.9 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EPS31353.1 - 5e-08 32.8 0.0 1e-07 31.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EPS31353.1 - 0.00015 20.3 0.1 0.0013 17.3 0.0 1.9 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) Esterase PF00756.15 EPS31353.1 - 0.011 15.1 0.2 0.024 14.0 0.2 1.6 1 1 0 1 1 1 0 Putative esterase Sec63 PF02889.11 EPS31354.1 - 1.7e-195 648.4 0.0 6e-107 357.4 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EPS31354.1 - 3.2e-55 186.1 1.5 6.5e-30 103.8 0.0 4.3 5 0 0 5 5 5 2 DEAD/DEAH box helicase ResIII PF04851.10 EPS31354.1 - 7.5e-16 58.4 0.0 7.9e-07 29.0 0.0 2.8 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EPS31354.1 - 1.5e-09 37.5 0.0 1.6e-08 34.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EPS31354.1 - 3.5e-06 27.1 0.4 0.0076 16.3 0.1 3.5 2 2 0 2 2 2 2 AAA domain T2SE PF00437.15 EPS31354.1 - 0.00032 19.6 0.0 1.4 7.7 0.0 3.2 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_19 PF13245.1 EPS31354.1 - 0.001 18.7 0.0 0.16 11.7 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain PhoH PF02562.11 EPS31354.1 - 0.0025 17.0 0.0 0.57 9.3 0.0 3.0 2 0 0 2 2 2 1 PhoH-like protein AAA_10 PF12846.2 EPS31354.1 - 0.0029 17.0 5.7 2 7.7 0.0 5.0 5 2 1 6 6 6 2 AAA-like domain FtsK_SpoIIIE PF01580.13 EPS31354.1 - 0.013 14.9 0.0 0.34 10.3 0.0 2.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family MutS_V PF00488.16 EPS31355.1 - 6.1e-84 281.1 0.0 1e-83 280.3 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EPS31355.1 - 7.4e-44 149.9 0.1 7.1e-43 146.7 0.1 2.2 1 1 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EPS31355.1 - 4e-19 68.7 0.0 1.3e-18 67.0 0.0 1.9 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 EPS31355.1 - 3.7e-06 27.0 0.0 1e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EPS31355.1 - 0.00048 20.2 0.0 0.0014 18.7 0.0 1.9 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.1 EPS31355.1 - 0.03 13.8 0.0 0.075 12.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 EPS31355.1 - 0.07 13.0 0.0 0.79 9.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EPS31355.1 - 0.19 12.0 0.0 0.59 10.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain RNase_P_p30 PF01876.11 EPS31357.1 - 5e-50 168.6 0.0 7.4e-50 168.0 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit p30 Pkinase PF00069.20 EPS31358.1 - 3.4e-58 196.8 0.1 3.9e-58 196.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS31358.1 - 6.3e-19 68.0 0.0 8.7e-19 67.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPS31358.1 - 1.4e-07 31.5 0.4 0.0001 22.1 0.1 2.7 2 1 1 3 3 3 2 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPS31358.1 - 0.0078 15.8 0.0 0.024 14.2 0.0 1.7 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.1 EPS31358.1 - 0.016 14.1 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 EPS31358.1 - 0.021 13.8 0.0 0.03 13.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Aconitase_B_N PF11791.3 EPS31358.1 - 0.059 13.1 0.1 0.21 11.3 0.0 1.8 2 0 0 2 2 2 0 Aconitate B N-terminal domain tRNA-synt_1 PF00133.17 EPS31359.1 - 5.7e-218 724.7 0.0 5.7e-218 724.7 0.0 2.3 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EPS31359.1 - 6e-32 110.5 1.6 6e-32 110.5 1.1 2.5 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EPS31359.1 - 2.4e-17 62.7 0.3 6.9e-08 31.5 0.0 5.0 4 2 0 5 5 5 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EPS31359.1 - 2.3e-08 33.5 3.7 2.5e-05 23.6 0.0 3.1 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 EPS31359.1 - 0.041 12.9 0.0 0.32 10.0 0.0 2.3 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain Brix PF04427.13 EPS31360.1 - 5.3e-31 107.7 0.0 7e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 Brix domain Tim17 PF02466.14 EPS31361.1 - 2.1e-24 85.9 0.5 3.4e-24 85.3 0.3 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF3716 PF12511.3 EPS31362.1 - 1.7e-13 49.9 7.4 3.1e-13 49.1 5.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) DUF3431 PF11913.3 EPS31364.1 - 3.7e-84 281.6 0.0 4.8e-84 281.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Mito_carr PF00153.22 EPS31365.1 - 4.9e-69 228.1 1.9 4.5e-23 80.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Chromate_transp PF02417.10 EPS31365.1 - 0.033 13.7 2.5 0.11 12.0 0.2 2.4 2 0 0 2 2 2 0 Chromate transporter zf-rbx1 PF12678.2 EPS31366.1 - 3e-12 46.4 0.3 6.2e-12 45.4 0.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EPS31366.1 - 4.7e-09 35.9 9.2 3.7e-08 33.0 6.4 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EPS31366.1 - 3.4e-07 29.8 0.5 7.8e-07 28.6 0.3 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPS31366.1 - 1e-06 28.3 4.0 6.8e-06 25.6 1.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPS31366.1 - 1.3e-05 25.1 1.7 1.3e-05 25.1 1.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPS31366.1 - 0.00023 20.8 4.1 0.0017 18.0 3.2 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EPS31366.1 - 0.0015 18.2 3.0 0.0048 16.5 2.1 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 EPS31366.1 - 0.0062 16.3 4.2 0.092 12.5 2.9 2.4 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EPS31366.1 - 0.055 13.3 1.0 0.12 12.2 0.7 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EPS31366.1 - 0.19 11.3 1.6 0.47 10.0 1.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain CopD PF05425.8 EPS31366.1 - 0.49 10.6 9.1 0.13 12.4 1.0 2.5 1 1 1 2 2 2 0 Copper resistance protein D OmpH PF03938.9 EPS31366.1 - 2.5 8.0 4.8 7.5 6.4 0.2 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Ceramidase PF05875.7 EPS31367.1 - 5.8e-79 264.9 3.4 6.7e-79 264.7 2.3 1.0 1 0 0 1 1 1 1 Ceramidase SLAC1 PF03595.12 EPS31367.1 - 0.0044 15.7 5.2 0.0044 15.7 3.6 2.4 2 1 1 3 3 3 1 Voltage-dependent anion channel Leader_Trp PF08255.6 EPS31367.1 - 0.15 11.7 2.9 0.45 10.2 2.0 1.8 1 0 0 1 1 1 0 Trp-operon Leader Peptide EamA PF00892.15 EPS31367.1 - 0.75 9.8 15.0 0.79 9.7 2.1 3.0 3 1 0 3 3 3 0 EamA-like transporter family ABC2_membrane_5 PF13346.1 EPS31367.1 - 1.2 8.3 12.6 31 3.7 5.8 3.1 2 1 0 2 2 2 0 ABC-2 family transporter protein Fib_alpha PF08702.5 EPS31368.1 - 0.0015 18.6 1.2 0.0029 17.7 0.9 1.4 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family P4Ha_N PF08336.6 EPS31368.1 - 0.021 14.6 0.3 0.033 13.9 0.2 1.3 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region 2-ph_phosp PF04029.9 EPS31368.1 - 0.037 12.9 0.2 0.062 12.2 0.1 1.3 1 0 0 1 1 1 0 2-phosphosulpholactate phosphatase SlyX PF04102.7 EPS31368.1 - 0.16 12.3 0.8 0.6 10.5 0.4 2.0 1 1 0 1 1 1 0 SlyX FNIP_N PF14636.1 EPS31368.1 - 1 9.8 5.4 0.6 10.5 1.1 2.4 3 1 0 3 3 3 0 Folliculin-interacting protein N-terminus MFS_1 PF07690.11 EPS31369.1 - 1.4e-24 86.4 24.9 4.9e-12 45.2 0.6 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily ATG22 PF11700.3 EPS31369.1 - 1.4e-10 40.2 0.0 0.00013 20.5 0.0 2.4 2 1 0 2 2 2 2 Vacuole effluxer Atg22 like MFS_2 PF13347.1 EPS31369.1 - 2.1e-07 29.6 13.2 0.0006 18.3 1.3 3.5 4 0 0 4 4 4 3 MFS/sugar transport protein MFS_1_like PF12832.2 EPS31369.1 - 0.0029 17.3 5.7 0.55 10.0 0.1 3.7 4 0 0 4 4 4 2 MFS_1 like family p450 PF00067.17 EPS31372.1 - 4.8e-66 223.1 0.0 6e-66 222.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 EPS31373.1 - 5.4e-23 81.4 0.0 9.5e-23 80.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS31373.1 - 1.3e-09 38.5 0.0 1.3e-08 35.3 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPS31373.1 - 9.9e-09 35.5 0.0 7.8e-08 32.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPS31373.1 - 1.4e-08 35.1 0.0 1.2e-07 32.1 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPS31373.1 - 2.9e-08 33.4 0.0 4e-07 29.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPS31373.1 - 0.00017 21.8 0.0 0.00054 20.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EPS31373.1 - 0.001 18.1 0.0 0.011 14.7 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_16 PF10294.4 EPS31373.1 - 0.0018 17.7 0.0 0.0041 16.6 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 EPS31373.1 - 0.002 18.1 0.0 0.092 12.7 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPS31373.1 - 0.0036 16.6 0.0 0.098 12.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.14 EPS31373.1 - 0.014 15.3 0.0 0.032 14.2 0.0 1.5 2 0 0 2 2 2 0 FtsJ-like methyltransferase PrmA PF06325.8 EPS31373.1 - 0.017 14.2 0.0 0.031 13.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) GidB PF02527.10 EPS31373.1 - 0.026 13.6 0.0 0.39 9.8 0.0 2.0 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G Ubie_methyltran PF01209.13 EPS31373.1 - 0.13 11.3 0.0 0.9 8.5 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Rabaptin PF03528.10 EPS31373.1 - 0.13 12.1 0.1 0.27 11.1 0.1 1.4 1 0 0 1 1 1 0 Rabaptin CMAS PF02353.15 EPS31373.1 - 0.14 11.2 0.0 0.27 10.2 0.0 1.5 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Ras PF00071.17 EPS31374.1 - 1.1e-05 24.9 0.0 1.5e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Glyco_hydro_71 PF03659.9 EPS31375.1 - 1.7e-150 500.8 4.6 2e-150 500.6 2.6 1.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 71 Peptidase_S8 PF00082.17 EPS31375.1 - 6.3e-14 51.7 0.0 1.1e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 Subtilase family RPN7 PF10602.4 EPS31376.1 - 3.3e-54 182.9 0.8 4.8e-54 182.3 0.1 1.7 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.22 EPS31376.1 - 2.7e-10 40.4 0.3 1.9e-09 37.7 0.0 2.3 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.12 EPS31376.1 - 0.00042 20.0 1.8 0.94 9.5 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat MHC_I_C PF06623.6 EPS31376.1 - 0.065 12.7 0.3 0.15 11.5 0.2 1.6 1 0 0 1 1 1 0 MHC_I C-terminus TPR_11 PF13414.1 EPS31376.1 - 0.071 12.7 0.3 16 5.1 0.0 3.0 3 0 0 3 3 3 0 TPR repeat TPR_1 PF00515.23 EPS31376.1 - 0.14 11.8 1.4 15 5.3 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EPS31376.1 - 0.22 12.2 7.9 14 6.5 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat adh_short PF00106.20 EPS31377.1 - 5.5e-15 55.6 0.0 7.4e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPS31377.1 - 2.6e-05 23.9 0.0 4.2e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EPS31377.1 - 0.00014 21.7 0.0 0.00018 21.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Peptidase_S26 PF10502.4 EPS31377.1 - 0.0031 17.0 0.1 0.011 15.3 0.0 1.9 2 0 0 2 2 2 1 Signal peptidase, peptidase S26 Eno-Rase_NADH_b PF12242.3 EPS31377.1 - 0.044 13.5 0.1 0.21 11.4 0.1 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EPS31377.1 - 0.068 13.1 0.0 0.17 11.9 0.0 1.7 1 1 0 1 1 1 0 NADH(P)-binding Toxin_65 PF15543.1 EPS31378.1 - 0.044 13.4 0.0 0.084 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative toxin 65 TcdA_TcdB_pore PF12920.2 EPS31378.1 - 7.6 4.3 7.3 9.2 4.0 5.0 1.1 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain PX PF00787.19 EPS31381.1 - 3.1e-18 65.6 0.0 1.2e-17 63.7 0.0 1.8 2 0 0 2 2 2 1 PX domain Troponin-I_N PF11636.3 EPS31381.1 - 0.017 14.8 1.6 0.041 13.5 1.1 1.6 1 0 0 1 1 1 0 Troponin I residues 1-32 DUF2156 PF09924.4 EPS31382.1 - 9.7e-31 106.6 0.0 1.4e-30 106.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) Phosphoesterase PF04185.9 EPS31385.1 - 7.6e-65 219.5 0.1 1.4e-64 218.6 0.0 1.4 1 1 0 1 1 1 1 Phosphoesterase family Zn_clus PF00172.13 EPS31387.1 - 5e-08 32.7 8.5 8.9e-08 31.9 5.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EPS31387.1 - 1.1e-06 27.5 0.1 1.7e-06 26.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF2457 PF10446.4 EPS31388.1 - 0.18 10.4 4.6 0.26 9.9 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sulfatase PF00884.18 EPS31390.1 - 4.7e-15 55.5 1.7 9.7e-15 54.5 1.2 1.5 1 1 0 1 1 1 1 Sulfatase DUF2913 PF11140.3 EPS31390.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2913) MFS_1 PF07690.11 EPS31391.1 - 4e-54 183.6 51.7 8.3e-40 136.5 16.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EPS31391.1 - 0.0012 16.9 0.5 0.12 10.3 0.0 2.5 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Anophelin PF10731.4 EPS31391.1 - 0.07 13.2 0.0 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito DUF1304 PF06993.7 EPS31391.1 - 0.44 10.2 9.0 0.024 14.3 1.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1304) DUF2633 PF11119.3 EPS31391.1 - 2.2 8.0 6.7 6.4 6.5 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) DUF1688 PF07958.6 EPS31392.1 - 1.6e-160 534.2 0.0 1.8e-160 534.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Aldedh PF00171.17 EPS31393.1 - 2.8e-143 477.6 0.1 3.4e-143 477.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EPS31393.1 - 8.8e-07 27.9 0.0 1.4e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 EPS31393.1 - 0.0013 17.9 0.1 0.28 10.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) DUF59 PF01883.14 EPS31393.1 - 0.052 13.5 0.4 0.13 12.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF59 AAA_12 PF13087.1 EPS31394.1 - 1.4e-35 122.4 0.0 2.9e-35 121.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EPS31394.1 - 4.8e-21 75.4 0.1 1.8e-20 73.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPS31394.1 - 1.2e-06 28.1 0.1 8e-06 25.5 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain DUF2075 PF09848.4 EPS31394.1 - 3.1e-06 26.4 0.3 0.0061 15.5 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 EPS31394.1 - 0.0017 18.3 0.3 0.013 15.4 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.1 EPS31394.1 - 0.022 14.3 0.1 0.4 10.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain UvrD_C_2 PF13538.1 EPS31394.1 - 0.14 12.3 0.0 0.39 10.8 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DUF3659 PF12396.3 EPS31396.1 - 1.1e-185 601.5 85.0 7.4e-24 83.2 0.5 9.4 9 0 0 9 9 9 9 Protein of unknown function (DUF3659) RPW8 PF05659.6 EPS31396.1 - 0.13 11.7 0.4 0.31 10.5 0.3 1.5 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Syntaxin_2 PF14523.1 EPS31396.1 - 7.5 6.6 8.8 3.8 7.5 0.3 2.8 3 0 0 3 3 3 0 Syntaxin-like protein DUF2229 PF09989.4 EPS31396.1 - 7.9 5.8 5.2 1.3 8.4 0.1 2.1 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) Acetyltransf_1 PF00583.19 EPS31397.1 - 1.7e-05 24.7 0.0 3.4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPS31397.1 - 0.0062 16.6 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Mito_carr PF00153.22 EPS31398.1 - 5.9e-67 221.4 2.8 2.4e-22 78.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein TauD PF02668.11 EPS31399.1 - 1.4e-59 201.8 0.2 2.7e-59 200.9 0.1 1.4 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 EPS31399.1 - 0.0012 17.7 0.1 0.0075 15.2 0.0 2.0 2 0 0 2 2 2 1 CsiD DUF971 PF06155.7 EPS31399.1 - 0.065 13.6 0.0 0.19 12.1 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF971) Glutaredoxin PF00462.19 EPS31400.1 - 3e-19 68.7 0.0 2.6e-17 62.5 0.0 2.7 2 1 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 EPS31400.1 - 4.3e-13 48.8 0.0 9.9e-13 47.6 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EPS31400.1 - 0.00044 20.3 0.0 0.0028 17.7 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like RNase_T PF00929.19 EPS31401.1 - 1.7e-23 83.7 0.0 2.7e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Exonuclease MFS_1 PF07690.11 EPS31402.1 - 2.6e-20 72.4 80.6 3.7e-15 55.4 32.5 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Beta_elim_lyase PF01212.16 EPS31404.1 - 6.1e-69 232.3 0.0 7.1e-69 232.1 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EPS31404.1 - 4.5e-05 21.9 0.0 7.2e-05 21.2 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.15 EPS31404.1 - 0.13 10.7 0.0 0.2 10.1 0.0 1.2 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Pkinase PF00069.20 EPS31405.1 - 4.1e-71 239.1 0.0 5.8e-71 238.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS31405.1 - 5.6e-33 114.0 0.0 8.5e-33 113.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EPS31405.1 - 2e-10 40.6 0.3 9.7e-10 38.4 0.2 2.2 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.1 EPS31405.1 - 7.3e-06 25.1 0.0 1.5e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EPS31405.1 - 0.00044 20.0 0.1 0.39 10.4 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EPS31405.1 - 0.0014 17.6 0.1 0.003 16.6 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EPS31405.1 - 0.049 12.9 0.0 0.47 9.7 0.0 2.2 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL DUF3811 PF11656.3 EPS31405.1 - 0.1 12.6 0.2 0.47 10.5 0.0 2.0 2 0 0 2 2 2 0 YjbD family (DUF3811) Glyco_transf_34 PF05637.7 EPS31406.1 - 2.2e-64 217.2 0.4 2.7e-64 216.9 0.3 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family NDUFB10 PF10249.4 EPS31407.1 - 0.0051 16.9 0.0 0.006 16.7 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 BRO1 PF03097.13 EPS31408.1 - 0.00017 20.4 0.0 0.00079 18.2 0.0 2.0 2 1 0 2 2 2 1 BRO1-like domain MFS_1 PF07690.11 EPS31409.1 - 3.1e-37 128.1 23.3 4.2e-37 127.6 16.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Bromo_TP PF07524.8 EPS31410.1 - 4.5e-07 29.5 0.0 6.8e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TAFII55_N PF04658.8 EPS31411.1 - 7.1e-53 178.4 0.0 1.5e-52 177.4 0.0 1.5 1 0 0 1 1 1 1 TAFII55 protein conserved region Sigma70_ner PF04546.8 EPS31411.1 - 4.7 6.7 17.3 12 5.3 12.0 1.7 1 0 0 1 1 1 0 Sigma-70, non-essential region Vir_act_alpha_C PF10400.4 EPS31412.1 - 1 9.7 9.1 1.5 9.2 0.4 2.8 2 1 1 3 3 3 0 Virulence activator alpha C-term DinB_2 PF12867.2 EPS31412.1 - 8.7 6.7 6.8 1.8 8.8 0.7 2.1 1 1 1 2 2 2 0 DinB superfamily Abhydrolase_6 PF12697.2 EPS31413.1 - 6.1e-26 91.7 0.9 7.8e-26 91.3 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPS31413.1 - 9.5e-11 41.6 0.0 1.8e-10 40.7 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPS31413.1 - 2e-06 27.6 0.0 2.7e-06 27.1 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 EPS31413.1 - 5.9e-06 25.2 0.0 8.4e-06 24.7 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase Hydrolase_4 PF12146.3 EPS31413.1 - 0.00012 21.8 0.1 0.00025 20.8 0.1 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase2 PF12740.2 EPS31413.1 - 0.0022 16.9 0.0 0.0031 16.4 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme AXE1 PF05448.7 EPS31413.1 - 0.013 13.9 0.0 0.065 11.7 0.0 1.8 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) ECH PF00378.15 EPS31414.1 - 6.2e-20 71.3 0.0 8.3e-20 70.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family PRCC PF10253.4 EPS31416.1 - 0.017 15.8 0.1 0.036 14.7 0.1 1.5 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Ofd1_CTDD PF10637.4 EPS31417.1 - 8.3e-102 339.8 0.8 1.2e-95 319.6 0.7 2.1 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 EPS31417.1 - 1.5e-16 60.6 0.2 1.2e-15 57.8 0.0 2.3 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EPS31417.1 - 0.022 14.3 0.0 0.067 12.8 0.0 1.8 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF3662 PF12401.3 EPS31417.1 - 0.023 14.8 0.0 0.095 12.8 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2662) DUF1712 PF08217.6 EPS31417.1 - 0.22 9.7 0.0 0.57 8.3 0.0 1.5 1 1 1 2 2 2 0 Fungal domain of unknown function (DUF1712) BUD22 PF09073.5 EPS31417.1 - 0.46 9.4 12.6 0.79 8.7 8.7 1.3 1 0 0 1 1 1 0 BUD22 Afi1 PF07792.7 EPS31417.1 - 1.6 8.7 4.7 3.1 7.7 3.2 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking HLH PF00010.21 EPS31420.1 - 7.8e-16 57.5 1.2 1.8e-15 56.3 0.8 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Fzo_mitofusin PF04799.8 EPS31420.1 - 0.25 10.6 2.7 0.38 10.1 1.9 1.2 1 0 0 1 1 1 0 fzo-like conserved region DUF805 PF05656.9 EPS31422.1 - 0.13 12.0 0.1 0.26 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF805) Phosphodiest PF01663.17 EPS31424.1 - 6.3e-85 285.6 1.4 8.3e-85 285.2 0.0 1.7 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EPS31424.1 - 1.4e-05 24.4 0.0 0.03 13.5 0.0 2.3 1 1 1 2 2 2 2 Sulfatase PBP1_TM PF14812.1 EPS31424.1 - 0.62 10.4 24.2 2.5 8.4 0.0 3.6 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RRN3 PF05327.6 EPS31424.1 - 0.63 8.0 12.5 1.1 7.3 8.6 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Vfa1 PF08432.5 EPS31424.1 - 1.4 8.8 8.4 3.2 7.7 5.8 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Daxx PF03344.10 EPS31424.1 - 7.6 4.8 21.7 15 3.9 15.0 1.5 1 0 0 1 1 1 0 Daxx Family Sporozoite_P67 PF05642.6 EPS31424.1 - 9.3 3.9 10.6 16 3.1 7.3 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BCS1_N PF08740.6 EPS31425.1 - 4.1e-49 166.7 3.1 7.5e-49 165.8 2.2 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EPS31425.1 - 2.8e-17 63.1 0.0 4e-07 30.2 0.0 2.6 1 1 1 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EPS31425.1 - 1.6e-05 25.7 0.1 0.00011 23.0 0.0 2.5 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EPS31425.1 - 0.0017 18.4 0.0 0.0034 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 EPS31425.1 - 0.0049 15.8 0.0 0.011 14.7 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_18 PF13238.1 EPS31425.1 - 0.0072 16.6 0.1 0.037 14.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EPS31425.1 - 0.013 14.5 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EPS31425.1 - 0.014 15.0 0.0 0.037 13.7 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain KaiC PF06745.8 EPS31425.1 - 0.033 13.3 0.0 0.065 12.3 0.0 1.4 1 0 0 1 1 1 0 KaiC TIP49 PF06068.8 EPS31425.1 - 0.042 12.5 0.0 0.072 11.8 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_11 PF13086.1 EPS31425.1 - 0.08 12.5 0.0 0.53 9.8 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EPS31425.1 - 0.08 12.3 0.0 0.19 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EPS31425.1 - 0.08 12.6 0.0 0.29 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 EPS31425.1 - 0.095 12.2 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 EPS31425.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Kinesin PF00225.18 EPS31426.1 - 2.2e-112 375.1 0.0 3.4e-112 374.4 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 EPS31426.1 - 2.5e-42 143.8 0.1 5.4e-42 142.7 0.0 1.6 1 0 0 1 1 1 1 Kinesin protein PH PF00169.24 EPS31426.1 - 7.5e-08 32.5 0.0 2.2e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 PH domain KIF1B PF12423.3 EPS31426.1 - 9.6e-08 31.9 0.4 3.5e-07 30.1 0.3 2.1 1 0 0 1 1 1 1 Kinesin protein 1B FHA PF00498.21 EPS31426.1 - 1.7e-05 24.8 0.1 0.00026 21.0 0.0 3.0 3 0 0 3 3 3 1 FHA domain CBFB_NFYA PF02045.10 EPS31428.1 - 1.3e-30 105.6 4.1 2.2e-30 104.9 2.9 1.4 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Hus1 PF04005.7 EPS31428.1 - 0.031 13.2 0.0 0.043 12.7 0.0 1.2 1 0 0 1 1 1 0 Hus1-like protein DUF4604 PF15377.1 EPS31428.1 - 7.4 6.7 10.9 51 4.0 7.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4604) DUF4367 PF14285.1 EPS31429.1 - 0.052 12.8 0.0 0.081 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4367) DUF3350 PF11830.3 EPS31429.1 - 0.064 13.2 0.1 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3350) PRCC PF10253.4 EPS31429.1 - 0.71 10.5 6.1 1.3 9.6 4.2 1.4 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF605 PF04652.11 EPS31429.1 - 1.1 8.5 18.0 1.7 7.9 12.5 1.2 1 0 0 1 1 1 0 Vta1 like DUF4187 PF13821.1 EPS31430.1 - 1.5e-23 82.1 0.2 3.2e-23 81.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) DUF3546 PF12066.3 EPS31430.1 - 2e-23 82.5 1.7 3e-23 81.9 0.4 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) ARS2 PF04959.8 EPS31430.1 - 8.5e-11 42.4 0.0 8.5e-11 42.4 0.0 2.0 2 1 1 3 3 3 1 Arsenite-resistance protein 2 bZIP_1 PF00170.16 EPS31432.1 - 0.0011 18.8 11.4 0.0023 17.8 7.6 1.8 1 1 0 1 1 1 1 bZIP transcription factor Exonuc_VII_L PF02601.10 EPS31432.1 - 0.035 13.2 0.8 0.045 12.9 0.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit TEX13 PF15186.1 EPS31432.1 - 0.051 13.1 5.6 0.084 12.4 3.9 1.2 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family Cobalamin_bind PF01122.14 EPS31432.1 - 0.059 11.9 0.0 0.13 10.8 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic cobalamin-binding protein TPD PF14811.1 EPS31432.1 - 0.14 11.6 1.5 0.27 10.7 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function TPD sequence-motif TSC22 PF01166.13 EPS31432.1 - 0.3 11.0 2.5 1.2 9.1 1.7 2.0 1 1 0 1 1 1 0 TSC-22/dip/bun family bZIP_2 PF07716.10 EPS31432.1 - 1.1 9.1 13.8 0.059 13.2 3.8 2.2 2 0 0 2 2 2 0 Basic region leucine zipper bZIP_Maf PF03131.12 EPS31432.1 - 4 7.8 12.0 7.2 6.9 8.3 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor eIF-3_zeta PF05091.7 EPS31433.1 - 5.3e-191 635.7 0.0 6.3e-191 635.4 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Cupin_1 PF00190.17 EPS31434.1 - 1.5e-26 92.5 0.0 2.1e-14 53.1 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EPS31434.1 - 7.2e-24 83.0 0.2 8.9e-13 47.5 0.1 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EPS31434.1 - 8e-10 37.9 0.0 0.00024 20.4 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 EPS31434.1 - 1.5e-08 34.4 0.1 2.1e-05 24.2 0.0 2.3 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_6 PF12852.2 EPS31434.1 - 6.9e-07 29.0 0.1 0.012 15.2 0.0 2.3 2 0 0 2 2 2 2 Cupin Cupin_4 PF08007.7 EPS31434.1 - 0.00034 19.9 0.0 0.018 14.3 0.0 2.2 2 0 0 2 2 2 1 Cupin superfamily protein MannoseP_isomer PF01050.13 EPS31434.1 - 0.0012 18.4 0.0 0.063 12.8 0.0 2.2 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase 3-HAO PF06052.7 EPS31434.1 - 0.0034 16.8 0.0 0.0061 15.9 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase DUF1971 PF09313.6 EPS31434.1 - 0.033 13.8 0.0 0.077 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1971) ARD PF03079.9 EPS31434.1 - 0.12 12.3 0.0 0.54 10.2 0.0 1.9 2 0 0 2 2 2 0 ARD/ARD' family CSTF_C PF14304.1 EPS31436.1 - 0.058 12.6 2.5 0.08 12.2 1.7 1.2 1 0 0 1 1 1 0 Transcription termination and cleavage factor C-terminal Abhydro_lipase PF04083.11 EPS31439.1 - 4e-20 70.9 0.0 1.8e-19 68.8 0.0 2.1 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 EPS31439.1 - 1.2e-07 31.8 3.4 1.9e-07 31.2 1.3 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPS31439.1 - 0.00026 20.7 0.0 0.00065 19.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPS31439.1 - 0.019 14.5 0.1 0.043 13.3 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF1824 PF08854.5 EPS31440.1 - 0.066 12.8 0.0 0.097 12.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1824) Aa_trans PF01490.13 EPS31441.1 - 1.1e-53 182.2 39.4 1.2e-53 182.1 27.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein zf-LITAF-like PF10601.4 EPS31441.1 - 7.3 6.5 5.9 2 8.3 0.0 2.8 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain Sugar_tr PF00083.19 EPS31442.1 - 1.4e-127 425.9 27.1 1.6e-127 425.7 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS31442.1 - 1.4e-21 76.6 37.5 7.7e-15 54.4 9.6 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Metallophos PF00149.23 EPS31443.1 - 1.3e-11 44.3 0.1 1.1e-10 41.2 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Cation_efflux PF01545.16 EPS31444.1 - 8.4e-80 267.8 0.0 1.6e-79 266.9 0.0 1.4 1 1 0 1 1 1 1 Cation efflux family Zip PF02535.17 EPS31444.1 - 0.093 11.7 8.5 0.44 9.5 5.8 1.9 1 1 0 1 1 1 0 ZIP Zinc transporter Glyco_hydro_3 PF00933.16 EPS31445.1 - 3.2e-46 157.6 0.0 3.9e-46 157.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Abhydrolase_6 PF12697.2 EPS31446.1 - 8e-34 117.4 0.0 9.8e-34 117.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPS31446.1 - 7.5e-18 64.9 0.2 2.2e-16 60.1 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPS31446.1 - 2.9e-16 59.5 0.0 5.1e-16 58.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EPS31446.1 - 9.3e-07 29.2 0.0 1.1e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.15 EPS31446.1 - 3.8e-06 26.5 0.1 5.6e-06 25.9 0.0 1.3 1 1 0 1 1 1 1 Putative esterase PGAP1 PF07819.8 EPS31446.1 - 8.1e-06 25.5 0.1 1.5e-05 24.7 0.1 1.4 1 1 0 1 1 1 1 PGAP1-like protein Ser_hydrolase PF06821.8 EPS31446.1 - 0.0035 16.9 0.0 0.0048 16.5 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase DLH PF01738.13 EPS31446.1 - 0.0095 15.2 0.0 0.73 9.0 0.0 2.9 2 1 0 2 2 2 1 Dienelactone hydrolase family UPF0227 PF05728.7 EPS31446.1 - 0.013 15.2 0.1 0.021 14.5 0.1 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF2048 PF09752.4 EPS31446.1 - 0.016 14.0 0.0 0.13 11.1 0.0 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Abhydrolase_2 PF02230.11 EPS31446.1 - 0.019 14.4 0.0 0.22 10.9 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.3 EPS31446.1 - 0.049 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase DUF915 PF06028.6 EPS31446.1 - 0.063 12.3 0.0 5.4 6.0 0.0 2.1 1 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.20 EPS31446.1 - 0.1 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) MFS_1 PF07690.11 EPS31447.1 - 1.1e-38 132.9 57.8 9.4e-37 126.5 37.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EPS31447.1 - 3.9e-08 31.9 20.3 3.9e-08 31.9 14.0 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EPS31447.1 - 5.8e-05 21.8 19.2 5.8e-05 21.8 13.3 2.8 1 1 1 3 3 3 2 Sugar (and other) transporter Metallophos PF00149.23 EPS31448.1 - 7.4e-07 28.7 1.7 2e-05 24.0 1.2 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EPS31448.1 - 0.0021 17.8 0.0 0.0064 16.3 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain His_Phos_2 PF00328.17 EPS31449.1 - 2.2e-11 43.6 0.0 5.7e-11 42.3 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Glyco_transf_28 PF03033.15 EPS31451.1 - 5.6e-21 74.7 0.0 1.6e-20 73.3 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EPS31451.1 - 3.8e-07 29.0 0.0 5.8e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.6 EPS31451.1 - 0.00019 21.5 0.0 0.00061 19.8 0.0 1.9 1 0 0 1 1 1 1 ATG C terminal domain Glyco_tran_28_C PF04101.11 EPS31451.1 - 0.00037 20.1 0.0 0.00074 19.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain FAM196 PF15265.1 EPS31451.1 - 0.21 10.8 8.5 0.34 10.0 5.9 1.2 1 0 0 1 1 1 0 FAM196 family zf-DHHC PF01529.15 EPS31452.1 - 2.7e-34 118.0 3.7 2.7e-34 118.0 2.5 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase Transglut_core3 PF13471.1 EPS31452.1 - 0.036 13.8 3.1 0.085 12.6 2.2 1.6 1 0 0 1 1 1 0 Transglutaminase-like superfamily HATPase_c PF02518.21 EPS31453.1 - 1.5e-12 47.2 0.1 3.7e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 EPS31453.1 - 6.6e-11 41.7 0.0 1.3e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EPS31453.1 - 1.4e-09 37.7 0.0 3.7e-09 36.3 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Kelch_5 PF13854.1 EPS31454.1 - 2.5e-15 56.0 1.2 2.5e-15 56.0 0.8 2.5 3 0 0 3 3 3 1 Kelch motif Kelch_1 PF01344.20 EPS31454.1 - 3.3e-06 26.5 0.1 0.0068 15.9 0.1 2.7 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.1 EPS31454.1 - 0.0004 20.4 1.5 0.039 14.1 0.1 3.6 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_4 PF13418.1 EPS31454.1 - 0.0011 18.7 1.6 0.069 12.9 0.0 3.2 2 1 0 2 2 2 1 Galactose oxidase, central domain Kelch_2 PF07646.10 EPS31454.1 - 0.057 13.2 0.0 1.8 8.4 0.0 2.8 2 1 0 2 2 2 0 Kelch motif EthD PF07110.6 EPS31456.1 - 9.4e-16 58.5 0.2 1.4e-15 57.9 0.2 1.3 1 0 0 1 1 1 1 EthD domain DUF1295 PF06966.7 EPS31457.1 - 5.7e-33 114.1 0.0 7.9e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 EPS31457.1 - 7.7e-05 22.4 0.0 0.00065 19.4 0.0 2.2 2 0 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 EPS31457.1 - 0.00051 20.1 0.0 0.0012 18.8 0.0 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.9 EPS31457.1 - 0.0013 18.9 0.3 0.0028 17.8 0.0 1.8 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.12 EPS31457.1 - 0.0049 15.4 0.0 0.0075 14.8 0.0 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Epimerase PF01370.16 EPS31459.1 - 3.5e-10 39.7 0.5 2.7e-05 23.7 0.1 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EPS31459.1 - 1.1e-07 32.1 0.2 3.6e-07 30.5 0.1 1.9 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 EPS31459.1 - 1.6e-05 24.2 0.3 2.5e-05 23.6 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 EPS31459.1 - 1.8e-05 23.5 0.0 0.0061 15.2 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family DXP_reductoisom PF02670.11 EPS31459.1 - 0.00022 21.7 0.1 0.00039 20.9 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase NAD_binding_10 PF13460.1 EPS31459.1 - 0.00022 21.2 0.5 0.00039 20.4 0.3 1.7 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EPS31459.1 - 0.00053 19.0 0.3 0.00082 18.4 0.2 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 EPS31459.1 - 0.037 12.9 0.0 0.072 12.0 0.0 1.6 1 1 0 1 1 1 0 Male sterility protein DapB_N PF01113.15 EPS31459.1 - 0.094 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus MFS_1 PF07690.11 EPS31460.1 - 4.9e-46 157.0 58.8 2.7e-44 151.3 41.9 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPS31460.1 - 2.5e-25 88.7 27.3 3.8e-25 88.1 18.7 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EPS31460.1 - 1.1e-11 44.0 17.4 1.1e-11 44.0 12.1 3.9 2 1 1 4 4 4 1 Sugar (and other) transporter Pkinase PF00069.20 EPS31461.1 - 1.1e-71 241.0 0.0 3.7e-71 239.3 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS31461.1 - 2.5e-45 154.5 0.0 4.1e-45 153.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 EPS31461.1 - 1.9e-07 30.9 0.1 0.013 15.4 0.0 2.8 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 EPS31461.1 - 1.5e-06 27.3 0.0 3.2e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like OPA3 PF07047.7 EPS31462.1 - 4e-34 117.2 3.4 7.1e-34 116.4 2.4 1.4 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) DUF2360 PF10152.4 EPS31462.1 - 0.43 10.8 8.0 3.9 7.7 1.2 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Myosin_head PF00063.16 EPS31463.1 - 7e-234 777.9 1.1 1.1e-233 777.3 0.8 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EPS31463.1 - 9.1e-51 172.0 0.0 1.7e-50 171.1 0.0 1.5 1 0 0 1 1 1 1 Myosin tail SH3_1 PF00018.23 EPS31463.1 - 9e-13 47.3 0.1 1.9e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EPS31463.1 - 2.2e-09 36.7 0.0 6.8e-09 35.1 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EPS31463.1 - 2.7e-08 33.1 0.0 9.1e-08 31.4 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain AAA_22 PF13401.1 EPS31463.1 - 0.0056 16.8 0.0 0.02 15.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain bPH_3 PF14470.1 EPS31463.1 - 0.011 15.9 0.0 0.043 14.0 0.0 2.0 1 0 0 1 1 1 0 Bacterial PH domain IQ PF00612.22 EPS31463.1 - 0.012 15.2 8.1 0.47 10.2 0.7 2.6 2 0 0 2 2 2 0 IQ calmodulin-binding motif Zeta_toxin PF06414.7 EPS31463.1 - 0.013 14.6 0.1 0.042 12.9 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin Hpr_kinase_C PF07475.7 EPS31463.1 - 0.029 13.6 0.7 4.5 6.5 0.0 2.8 3 0 0 3 3 3 0 HPr Serine kinase C-terminal domain NACHT PF05729.7 EPS31463.1 - 0.054 13.1 0.0 0.23 11.1 0.0 2.0 2 0 0 2 2 2 0 NACHT domain DUF2075 PF09848.4 EPS31463.1 - 0.073 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 EPS31463.1 - 0.082 13.7 0.0 0.24 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF3759 PF12585.3 EPS31464.1 - 0.22 11.4 5.4 0.04 13.8 1.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3759) WD40 PF00400.27 EPS31465.1 - 4.9e-09 35.7 1.4 6.2e-08 32.2 0.1 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF2415 PF10313.4 EPS31465.1 - 0.03 13.9 0.0 0.099 12.3 0.0 1.9 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) Chitin_synth_2 PF03142.10 EPS31466.1 - 1.7e-292 970.5 0.1 2.6e-292 969.9 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EPS31466.1 - 9.8e-17 61.2 0.9 9.8e-17 61.2 0.6 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EPS31466.1 - 1.9e-13 50.7 0.2 7.2e-12 45.5 0.0 2.7 3 0 0 3 3 3 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 EPS31466.1 - 1.7e-11 43.7 0.1 1.5e-07 31.1 0.0 2.5 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.21 EPS31466.1 - 0.00011 21.9 0.1 0.0034 17.0 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EPS31466.1 - 0.00015 21.1 0.1 0.00088 18.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 Abhydrolase_6 PF12697.2 EPS31467.1 - 7.5e-24 84.8 2.1 8.9e-24 84.6 1.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPS31467.1 - 1.3e-11 44.4 0.0 1.6e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPS31467.1 - 1.2e-06 28.2 0.1 2.3e-06 27.3 0.0 1.5 1 1 0 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EPS31467.1 - 0.0022 18.2 0.0 0.0029 17.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain ADH_N PF08240.7 EPS31468.1 - 4.3e-07 29.6 0.1 1.4e-06 28.0 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain GPP34 PF05719.6 EPS31468.1 - 0.071 13.1 0.0 0.57 10.2 0.0 2.2 2 0 0 2 2 2 0 Golgi phosphoprotein 3 (GPP34) DUF1859 PF08948.5 EPS31469.1 - 0.067 12.9 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1859) Sel1 PF08238.7 EPS31473.1 - 5.7e-37 125.3 26.1 2.1e-06 28.1 0.1 7.5 7 0 0 7 7 7 7 Sel1 repeat PARP PF00644.15 EPS31474.1 - 2.9e-62 209.7 0.3 2.6e-61 206.6 0.0 2.3 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 EPS31474.1 - 2.3e-42 143.8 0.1 3.9e-42 143.0 0.1 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 EPS31474.1 - 1e-21 76.6 0.0 1e-21 76.6 0.0 2.0 2 0 0 2 2 2 1 WGR domain BRCT PF00533.21 EPS31474.1 - 3.3e-09 36.7 0.0 7.2e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EPS31474.1 - 4.6e-07 29.5 0.1 8.6e-07 28.7 0.1 1.5 1 0 0 1 1 1 1 twin BRCT domain PfkB PF00294.19 EPS31475.1 - 9.6e-38 130.0 5.4 1.2e-37 129.6 3.7 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Zn_clus PF00172.13 EPS31476.1 - 4.5e-09 36.0 10.6 8.4e-09 35.1 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 EPS31477.1 - 4.3e-22 78.5 0.0 5.6e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS31477.1 - 1.6e-08 33.9 0.3 1.8e-07 30.5 0.0 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EPS31477.1 - 0.0086 15.0 0.3 0.42 9.5 0.2 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EPS31477.1 - 0.0096 15.6 0.5 0.025 14.3 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Sugar_tr PF00083.19 EPS31478.1 - 9.5e-110 367.2 31.3 1.9e-109 366.2 21.7 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS31478.1 - 1.6e-23 83.0 59.8 5.5e-15 54.9 17.9 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 EPS31478.1 - 7.9e-05 21.2 44.2 0.00024 19.6 7.8 3.9 2 2 1 3 3 3 2 MFS/sugar transport protein Fungal_trans_2 PF11951.3 EPS31479.1 - 9.6e-10 37.5 0.0 2e-09 36.5 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Aa_trans PF01490.13 EPS31480.1 - 1.6e-39 135.6 35.6 1.9e-39 135.3 24.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Ank_2 PF12796.2 EPS31482.1 - 1.4e-53 179.1 1.5 9.1e-15 54.7 0.1 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EPS31482.1 - 7.4e-48 158.0 15.3 2.5e-07 30.1 0.0 7.4 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.1 EPS31482.1 - 9.1e-41 137.5 9.0 1.5e-10 41.3 0.0 6.3 1 1 4 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPS31482.1 - 5.1e-36 119.1 2.1 4.4e-05 23.3 0.1 7.9 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.1 EPS31482.1 - 2.3e-33 113.4 13.6 3.5e-07 30.2 0.2 7.7 3 2 5 8 8 8 7 Ankyrin repeats (many copies) FA PF08736.6 EPS31482.1 - 0.00027 20.6 4.0 1.3 8.8 0.2 4.3 4 0 0 4 4 4 2 FERM adjacent (FA) Glyco_hydro_26 PF02156.10 EPS31483.1 - 3.6e-84 282.8 1.7 5.6e-84 282.2 1.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 CBM_1 PF00734.13 EPS31483.1 - 6.5e-12 44.8 12.2 6.5e-12 44.8 8.4 3.0 3 0 0 3 3 3 1 Fungal cellulose binding domain Glyco_hydro_12 PF01670.11 EPS31484.1 - 1.2e-54 184.3 1.5 1.2e-54 184.3 1.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 12 Glyco_hydro_17 PF00332.13 EPS31486.1 - 0.0037 16.3 0.4 0.14 11.1 0.2 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 Crust_neurohorm PF01147.12 EPS31487.1 - 0.054 12.8 0.1 0.094 12.0 0.1 1.3 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family AcetylCoA_hydro PF02550.10 EPS31489.1 - 8.7e-50 169.2 0.0 1.3e-49 168.6 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 EPS31489.1 - 1.4e-39 135.1 0.0 2.4e-39 134.4 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain PAH PF02671.16 EPS31490.1 - 3.6e-43 144.9 2.8 6.2e-17 60.9 0.5 3.7 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 EPS31490.1 - 2.9e-41 139.3 0.1 8e-41 137.8 0.0 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor JAB PF01398.16 EPS31490.1 - 0.16 11.6 0.0 0.16 11.6 0.0 1.9 2 0 0 2 2 2 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease WD40 PF00400.27 EPS31491.1 - 2.1e-13 49.5 2.3 0.07 13.0 0.2 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat SWI-SNF_Ssr4 PF08549.5 EPS31493.1 - 0.02 13.2 3.8 0.031 12.6 2.7 1.5 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) AhpC-TSA_2 PF13911.1 EPS31494.1 - 1.9e-09 37.4 0.0 2.5e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EPS31494.1 - 1.5e-06 27.8 0.0 2e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EPS31494.1 - 1.6e-05 24.5 0.0 2.1e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin FAD_binding_2 PF00890.19 EPS31495.1 - 4.3e-84 282.7 1.1 5.4e-84 282.4 0.8 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 EPS31495.1 - 8.8e-21 73.4 0.4 3.1e-19 68.5 0.0 3.1 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 EPS31495.1 - 4.8e-11 42.1 4.2 9.6e-10 37.8 2.9 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EPS31495.1 - 3e-09 37.0 0.0 2.9e-07 30.5 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EPS31495.1 - 6.2e-09 35.4 0.8 2.1e-08 33.7 0.5 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPS31495.1 - 1.8e-07 31.1 4.9 2.8e-07 30.4 0.6 3.0 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EPS31495.1 - 8.1e-06 25.0 1.0 0.0026 16.8 0.2 2.5 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.9 EPS31495.1 - 9.2e-06 24.3 4.8 0.0029 16.1 0.2 3.2 3 0 0 3 3 3 2 HI0933-like protein FAD_binding_3 PF01494.14 EPS31495.1 - 0.00017 20.7 0.1 0.00027 20.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 EPS31495.1 - 0.0011 17.9 2.5 0.13 11.0 0.4 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Amino_oxidase PF01593.19 EPS31495.1 - 0.0031 16.6 0.3 1 8.3 0.0 2.5 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 EPS31495.1 - 0.0042 16.8 1.0 0.031 14.0 0.7 2.3 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EPS31495.1 - 0.0089 16.0 1.1 0.033 14.2 0.8 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.13 EPS31495.1 - 0.25 9.6 0.1 0.39 8.9 0.1 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Pyr_redox PF00070.22 EPS31495.1 - 0.28 11.6 1.5 6.1 7.3 0.2 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Bac_rhamnosid PF05592.6 EPS31496.1 - 5e-187 622.1 0.0 9.2e-187 621.2 0.0 1.4 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 EPS31496.1 - 3.8e-57 192.5 0.0 6.4e-57 191.8 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Glyco_hydro_2_N PF02837.13 EPS31496.1 - 0.045 13.3 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain MBD PF01429.14 EPS31496.1 - 0.12 11.9 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Methyl-CpG binding domain Ion_trans_2 PF07885.11 EPS31497.1 - 1.5e-26 91.8 22.5 2.9e-16 58.9 6.8 3.9 5 0 0 5 5 5 2 Ion channel DUF3357 PF11837.3 EPS31497.1 - 0.071 12.9 1.3 3.2 7.6 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) PCI PF01399.22 EPS31498.1 - 1.7e-13 50.8 0.0 4.4e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.4 EPS31498.1 - 0.00012 21.5 0.1 0.00035 19.9 0.0 1.8 2 0 0 2 2 2 1 26S proteasome subunit RPN7 TPR_19 PF14559.1 EPS31498.1 - 0.075 13.3 4.5 0.14 12.5 0.0 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EPS31498.1 - 0.8 10.5 4.6 57 4.7 0.0 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat TFIIF_beta PF02270.10 EPS31499.1 - 2e-80 270.5 5.1 2.3e-80 270.3 3.5 1.0 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit zf-CCCH PF00642.19 EPS31500.1 - 2.1e-13 49.5 29.1 1.6e-05 24.4 1.0 5.2 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TFIIA PF03153.8 EPS31500.1 - 0.017 15.0 5.5 0.031 14.2 3.8 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-C3H1 PF10650.4 EPS31500.1 - 0.13 11.7 1.8 0.47 9.9 0.1 2.7 2 0 0 2 2 2 0 Putative zinc-finger domain LRV_FeS PF05484.6 EPS31500.1 - 1.2 8.7 6.2 4.4 6.9 0.3 3.5 2 1 1 3 3 3 0 LRV protein FeS4 cluster bZIP_2 PF07716.10 EPS31503.1 - 6.8e-08 32.2 21.7 1.3e-07 31.2 7.9 2.8 1 1 0 2 2 2 2 Basic region leucine zipper bZIP_Maf PF03131.12 EPS31503.1 - 2.1e-06 27.9 14.4 2.1e-06 27.9 10.0 2.3 1 1 1 2 2 2 1 bZIP Maf transcription factor bZIP_1 PF00170.16 EPS31503.1 - 0.00013 21.8 23.0 0.00024 20.9 11.6 2.7 2 0 0 2 2 2 1 bZIP transcription factor GA PF01468.12 EPS31503.1 - 0.11 12.6 3.2 5.7 7.1 0.2 2.5 2 0 0 2 2 2 0 GA module Jnk-SapK_ap_N PF09744.4 EPS31503.1 - 1.1 9.2 20.6 4.5 7.2 12.9 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF342 PF03961.8 EPS31503.1 - 5.1 5.3 11.8 8.6 4.6 8.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) F-box-like PF12937.2 EPS31504.1 - 1.2e-08 34.5 0.8 5.3e-08 32.4 0.6 2.3 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EPS31504.1 - 3.7 7.2 9.5 5.8 6.6 0.6 4.7 4 2 2 6 6 6 0 Leucine Rich repeats (2 copies) PAN_4 PF14295.1 EPS31505.1 - 0.00013 21.6 1.0 0.00024 20.7 0.7 1.5 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.21 EPS31505.1 - 0.00046 19.8 1.5 0.00078 19.1 1.0 1.3 1 1 0 1 1 1 1 PAN domain Zip PF02535.17 EPS31506.1 - 6.8e-54 183.0 1.5 7.9e-54 182.7 1.0 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter UNC-50 PF05216.8 EPS31506.1 - 0.53 9.4 2.7 0.4 9.8 0.4 1.8 2 0 0 2 2 2 0 UNC-50 family SKG6 PF08693.5 EPS31507.1 - 0.00027 20.1 0.1 0.00048 19.3 0.0 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Glycophorin_A PF01102.13 EPS31507.1 - 0.029 14.1 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 Glycophorin A Sel1 PF08238.7 EPS31508.1 - 1e-19 70.4 7.9 1.9e-06 28.3 0.1 3.5 3 0 0 3 3 3 3 Sel1 repeat TPR_6 PF13174.1 EPS31508.1 - 0.00071 19.8 4.4 2.3 8.8 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat Mt_ATP-synt_B PF05405.9 EPS31509.1 - 1.6e-52 177.2 6.4 2e-52 176.9 4.4 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF3573 PF12097.3 EPS31509.1 - 0.19 10.2 1.3 0.26 9.8 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Laps PF10169.4 EPS31509.1 - 0.64 10.2 3.7 0.99 9.6 2.3 1.4 1 1 0 1 1 1 0 Learning-associated protein PBP_sp32 PF07222.7 EPS31509.1 - 6 5.9 8.0 1.4 8.0 3.3 1.5 2 0 0 2 2 2 0 Proacrosin binding protein sp32 CBF PF03914.12 EPS31510.1 - 1.6e-48 164.3 0.3 3.3e-48 163.2 0.2 1.6 1 0 0 1 1 1 1 CBF/Mak21 family GPI-anchored PF10342.4 EPS31511.1 - 1.7e-16 60.4 0.1 1.7e-16 60.4 0.0 2.6 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Inhibitor_I10 PF12559.3 EPS31511.1 - 0.18 12.0 1.7 0.46 10.7 0.6 2.2 2 1 0 2 2 2 0 Serine endopeptidase inhibitors Atrophin-1 PF03154.10 EPS31511.1 - 2.5 6.1 13.6 3.2 5.7 9.4 1.1 1 0 0 1 1 1 0 Atrophin-1 family TFIIA PF03153.8 EPS31511.1 - 5.7 6.7 8.4 6.8 6.4 5.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Filament PF00038.16 EPS31512.1 - 0.019 14.4 32.9 0.18 11.2 22.8 2.2 1 1 0 1 1 1 0 Intermediate filament protein ADIP PF11559.3 EPS31512.1 - 8.3 6.2 33.7 2.3 8.1 7.5 2.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding HCV_env PF01539.12 EPS31513.1 - 0.13 11.7 0.8 0.17 11.3 0.2 1.5 2 0 0 2 2 2 0 Hepatitis C virus envelope glycoprotein E1 MMS19_C PF12460.3 EPS31515.1 - 1.5e-112 376.4 13.3 1.7e-112 376.2 4.0 3.5 2 1 0 4 4 4 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.1 EPS31515.1 - 1.9e-94 315.8 1.0 4.3e-94 314.6 0.0 2.2 3 0 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_2 PF13646.1 EPS31515.1 - 1e-07 32.1 10.4 0.023 14.9 0.1 6.6 5 1 1 6 6 6 2 HEAT repeats HEAT PF02985.17 EPS31515.1 - 0.003 17.5 17.0 1.1 9.5 0.2 6.4 7 0 0 7 7 7 3 HEAT repeat Arm PF00514.18 EPS31515.1 - 0.077 12.8 7.5 2.8 7.9 0.0 4.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Ipi1_N PF12333.3 EPS31515.1 - 2.1 8.3 7.4 79 3.2 0.0 5.5 4 2 1 5 5 5 0 Rix1 complex component involved in 60S ribosome maturation HEAT_EZ PF13513.1 EPS31515.1 - 3.9 8.0 20.3 5.6 7.5 1.2 6.8 8 1 0 8 8 8 0 HEAT-like repeat Fasciclin PF02469.17 EPS31516.1 - 1.7e-05 24.8 0.0 3.6e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 Fasciclin domain DUF106 PF01956.11 EPS31517.1 - 4e-55 185.8 0.4 5.8e-55 185.3 0.3 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF106 SPC25 PF06703.6 EPS31518.1 - 7.2e-45 152.4 0.1 8.2e-45 152.2 0.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) MBD PF01429.14 EPS31518.1 - 0.0022 17.4 0.1 0.0047 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyl-CpG binding domain THF_DHG_CYH PF00763.18 EPS31519.1 - 5.8e-19 68.2 0.1 8.4e-19 67.7 0.1 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 EPS31519.1 - 1.4e-12 46.9 0.0 1.3e-10 40.5 0.0 2.7 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF3143 PF11341.3 EPS31519.1 - 0.064 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3143) Stc1 PF12898.2 EPS31520.1 - 0.085 12.9 0.0 0.093 12.8 0.0 1.2 1 0 0 1 1 1 0 Stc1 domain ATP-synt_ab PF00006.20 EPS31521.1 - 4.7e-71 238.7 0.0 6.6e-71 238.2 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EPS31521.1 - 1.9e-25 89.5 1.7 3.2e-25 88.7 0.4 2.1 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EPS31521.1 - 2.2e-15 56.6 3.1 6.5e-15 55.1 2.1 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EPS31521.1 - 0.0058 16.5 1.1 0.018 14.9 0.7 1.9 1 0 0 1 1 1 1 HAS barrel domain DUF962 PF06127.6 EPS31522.1 - 4.2e-25 87.4 1.0 5.8e-25 87.0 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF962) Transgly_assoc PF04226.8 EPS31522.1 - 0.58 10.2 5.1 10 6.2 0.4 2.6 1 1 1 2 2 2 0 Transglycosylase associated protein Asr PF06392.6 EPS31522.1 - 5.9 7.3 8.5 9.9 6.6 5.9 1.3 1 0 0 1 1 1 0 Acid shock protein repeat SHS2_Rpb7-N PF03876.12 EPS31523.1 - 1.7e-14 53.7 0.0 3e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EPS31523.1 - 3.3e-09 36.7 0.0 5.2e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain Piwi PF02171.12 EPS31527.1 - 5.7e-72 242.2 0.0 8.8e-72 241.6 0.0 1.3 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EPS31527.1 - 1.8e-11 43.1 0.0 4e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EPS31527.1 - 5.2e-11 41.9 0.0 1.4e-10 40.5 0.0 1.7 2 0 0 2 2 2 1 PAZ domain Fungal_trans PF04082.13 EPS31528.1 - 3.6e-16 58.8 0.1 7e-16 57.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS31528.1 - 1.5e-07 31.1 12.2 2.7e-07 30.3 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PRCH PF03967.8 EPS31528.1 - 0.041 13.4 0.0 0.084 12.4 0.0 1.4 1 0 0 1 1 1 0 Photosynthetic reaction centre, H-chain N-terminal region HSBP1 PF06825.7 EPS31528.1 - 0.067 12.7 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 RRM_1 PF00076.17 EPS31529.1 - 2.9e-33 113.3 0.4 1.4e-18 66.2 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS31529.1 - 2.5e-28 97.8 1.3 5.2e-14 51.9 0.0 3.3 4 0 0 4 4 4 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS31529.1 - 3.1e-10 39.7 0.0 6.6e-05 22.6 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_11 PF13414.1 EPS31530.1 - 1.1e-25 89.0 5.1 2.1e-11 43.2 0.4 4.4 3 1 1 4 4 4 4 TPR repeat TPR_2 PF07719.12 EPS31530.1 - 8.3e-23 78.4 3.1 1.5e-07 30.7 0.1 6.0 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_1 PF00515.23 EPS31530.1 - 1.4e-22 78.2 3.4 2.4e-08 33.2 0.0 5.9 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 EPS31530.1 - 6.4e-17 60.5 8.3 7.9e-05 22.9 0.0 6.2 6 1 2 8 8 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 EPS31530.1 - 1.2e-15 57.6 7.6 2.4e-06 28.0 0.0 4.9 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 EPS31530.1 - 2.8e-15 55.1 3.8 0.0012 18.9 0.1 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.1 EPS31530.1 - 2.8e-14 53.2 2.6 0.00056 20.1 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EPS31530.1 - 2.1e-13 49.9 4.9 2.9e-08 33.5 0.4 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EPS31530.1 - 4.2e-11 41.7 0.4 0.00038 20.0 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.1 EPS31530.1 - 4.7e-11 42.6 1.1 0.0054 16.8 0.0 4.9 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EPS31530.1 - 6.1e-10 38.1 3.9 0.001 18.7 0.0 6.6 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 EPS31530.1 - 3.8e-07 29.8 3.6 0.0029 17.4 0.0 4.0 4 0 0 4 4 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EPS31530.1 - 1.5e-06 28.2 2.0 3.5e-05 23.8 0.3 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EPS31530.1 - 1.4e-05 25.1 2.2 0.92 10.1 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_3 PF07720.7 EPS31530.1 - 0.0001 22.0 0.0 0.09 12.5 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.1 EPS31530.1 - 0.00059 18.9 0.2 0.5 9.3 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 EPS31530.1 - 0.0054 16.6 1.5 0.47 10.4 0.4 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.13 EPS31530.1 - 0.027 14.3 1.5 1.2 9.1 0.3 3.6 4 1 0 4 4 3 0 MIT (microtubule interacting and transport) domain TOM20_plant PF06552.7 EPS31530.1 - 0.028 13.9 0.1 1.5 8.3 0.0 3.1 3 1 1 4 4 4 0 Plant specific mitochondrial import receptor subunit TOM20 DUF1641 PF07849.6 EPS31530.1 - 0.048 13.2 0.3 0.21 11.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1641) Methyltransf_28 PF02636.12 EPS31531.1 - 6.3e-36 124.0 0.0 9.8e-36 123.4 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_18 PF12847.2 EPS31531.1 - 0.041 14.4 0.0 0.079 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PALP PF00291.20 EPS31532.1 - 3.3e-53 180.8 0.4 5e-53 180.3 0.3 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Scm3 PF10384.4 EPS31533.1 - 1.6e-21 75.5 0.1 3.6e-21 74.4 0.1 1.6 1 0 0 1 1 1 1 Centromere protein Scm3 Myb_DNA-bind_6 PF13921.1 EPS31533.1 - 0.024 14.7 0.5 4.6 7.4 0.2 3.1 3 0 0 3 3 3 0 Myb-like DNA-binding domain APG6 PF04111.7 EPS31534.1 - 1.9e-124 414.8 0.0 2.3e-124 414.5 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 CCDC155 PF14662.1 EPS31534.1 - 0.026 14.1 6.1 0.05 13.2 4.2 1.5 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 HoxA13_N PF12284.3 EPS31534.1 - 0.12 12.5 3.9 0.26 11.4 2.7 1.6 1 0 0 1 1 1 0 Hox protein A13 N terminal DUF4337 PF14235.1 EPS31534.1 - 0.15 11.8 2.3 0.29 10.9 1.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) V_ATPase_I PF01496.14 EPS31534.1 - 0.2 9.4 0.6 0.26 9.0 0.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TBPIP PF07106.8 EPS31534.1 - 0.2 11.1 1.9 0.32 10.5 1.3 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) MbeD_MobD PF04899.7 EPS31534.1 - 0.36 10.7 3.9 1.6 8.6 2.7 2.1 1 1 0 1 1 1 0 MbeD/MobD like bZIP_1 PF00170.16 EPS31534.1 - 0.87 9.5 3.8 2 8.4 2.2 2.1 1 1 0 1 1 1 0 bZIP transcription factor DivIC PF04977.10 EPS31534.1 - 1 8.8 4.6 2.3 7.7 3.2 1.6 1 0 0 1 1 1 0 Septum formation initiator DUF4164 PF13747.1 EPS31534.1 - 1.1 9.4 14.5 0.34 11.0 5.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) IncA PF04156.9 EPS31534.1 - 3.7 7.1 8.1 6 6.4 5.6 1.3 1 0 0 1 1 1 0 IncA protein Clr5 PF14420.1 EPS31537.1 - 2.3e-18 65.8 5.0 4.4e-18 64.9 3.5 1.5 1 0 0 1 1 1 1 Clr5 domain XisI PF08869.6 EPS31537.1 - 0.28 11.3 2.3 1.2 9.2 2.2 1.5 2 0 0 2 2 2 0 XisI protein PyrBI_leader PF08052.6 EPS31539.1 - 0.12 12.2 0.4 0.26 11.0 0.3 1.5 1 0 0 1 1 1 0 PyrBI operon leader peptide LysM PF01476.15 EPS31540.1 - 6e-06 26.0 0.2 0.00078 19.2 0.0 3.2 2 1 0 2 2 2 2 LysM domain Glyco_hydro_18 PF00704.23 EPS31542.1 - 3.7e-68 230.5 0.4 1.4e-67 228.5 0.2 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 DNase_NucA_NucB PF14040.1 EPS31542.1 - 0.00018 21.5 0.5 0.0025 17.9 0.2 2.3 2 0 0 2 2 2 1 Deoxyribonuclease NucA/NucB LysM PF01476.15 EPS31543.1 - 2.5e-24 84.8 0.4 1.5e-06 28.0 0.0 3.2 3 0 0 3 3 3 3 LysM domain HTH_23 PF13384.1 EPS31543.1 - 0.0018 17.8 0.1 7.5 6.3 0.0 3.2 3 0 0 3 3 3 2 Homeodomain-like domain HTH_Tnp_1 PF01527.15 EPS31543.1 - 0.016 15.1 0.0 42 4.1 0.0 3.2 3 0 0 3 3 3 0 Transposase HTH_28 PF13518.1 EPS31543.1 - 0.024 14.6 0.0 19 5.3 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain RNase_T PF00929.19 EPS31543.1 - 0.13 12.4 0.0 9.8 6.4 0.0 2.6 3 0 0 3 3 3 0 Exonuclease Monellin PF09200.5 EPS31543.1 - 0.16 11.6 0.0 31 4.2 0.0 2.6 2 0 0 2 2 2 0 Monellin Peroxin-13_N PF04088.8 EPS31544.1 - 1.1e-59 200.9 0.1 1.7e-59 200.3 0.0 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 EPS31544.1 - 1.5e-09 37.1 0.0 2.5e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EPS31544.1 - 2.2e-08 33.3 0.0 3.6e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EPS31544.1 - 1.9e-06 27.3 0.1 3e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain ERO1 PF04137.10 EPS31546.1 - 4e-140 466.8 0.0 5e-140 466.5 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) UPF0542 PF15086.1 EPS31547.1 - 0.043 13.5 0.7 0.078 12.6 0.1 1.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 DIM PF08194.7 EPS31547.1 - 0.066 13.1 1.5 0.1 12.5 1.1 1.5 1 1 0 1 1 1 0 DIM protein Pal1 PF08316.6 EPS31549.1 - 7.9e-12 45.8 0.2 1.7e-11 44.7 0.1 1.6 1 0 0 1 1 1 1 Pal1 cell morphology protein HVSL PF09749.4 EPS31551.1 - 1.4e-78 263.1 0.0 1.7e-78 262.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein DUF3807 PF12720.2 EPS31552.1 - 4.9e-41 140.7 0.7 5.5e-41 140.5 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) Aa_trans PF01490.13 EPS31553.1 - 4.2e-42 144.0 41.8 5e-42 143.8 29.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SAS4 PF15460.1 EPS31554.1 - 9.7e-30 102.4 9.7 2.5e-29 101.1 6.7 1.7 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 DHDPS PF00701.17 EPS31555.1 - 3.9e-51 173.3 0.0 4.6e-51 173.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Glyco_hydro_20 PF00728.17 EPS31556.1 - 5.2e-96 321.8 0.3 6.4e-96 321.5 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EPS31556.1 - 4.3e-26 92.0 0.0 8e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EPS31556.1 - 5.3e-06 26.9 0.1 1e-05 26.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Pkinase PF00069.20 EPS31557.1 - 2.3e-28 99.0 0.0 3.5e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS31557.1 - 9.1e-08 31.4 1.4 3.8e-06 26.1 1.0 2.8 1 1 0 1 1 1 1 Protein tyrosine kinase AIF-MLS PF14962.1 EPS31560.1 - 0.061 12.9 4.8 0.077 12.6 3.3 1.1 1 0 0 1 1 1 0 Mitochondria Localisation Sequence zf-C2H2_4 PF13894.1 EPS31562.1 - 0.00014 21.9 15.8 0.1 12.9 0.0 5.0 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EPS31562.1 - 0.0024 17.7 0.5 0.14 12.1 0.4 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.2 EPS31562.1 - 0.19 11.9 3.9 3.8 7.8 0.4 3.6 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EPS31562.1 - 0.22 11.9 28.5 0.86 10.0 0.1 6.1 7 0 0 7 7 7 0 Zinc finger, C2H2 type ATP_transf PF09830.4 EPS31563.1 - 4.6e-21 74.3 0.0 7.5e-21 73.6 0.0 1.3 1 0 0 1 1 1 1 ATP adenylyltransferase LtrA PF06772.6 EPS31565.1 - 1.4e-14 53.7 19.1 1.4e-14 53.7 13.3 1.8 2 0 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) NTR2 PF15458.1 EPS31566.1 - 5.2e-74 248.6 17.8 8.6e-74 247.9 12.4 1.3 1 0 0 1 1 1 1 Nineteen complex-related protein 2 Nup54 PF13874.1 EPS31566.1 - 0.046 13.3 0.3 0.046 13.3 0.2 2.2 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 IncA PF04156.9 EPS31566.1 - 3.9 7.0 6.9 2.7 7.5 0.2 2.2 2 0 0 2 2 2 0 IncA protein LSM PF01423.17 EPS31567.1 - 6.6e-20 70.4 0.3 7.6e-20 70.2 0.2 1.0 1 0 0 1 1 1 1 LSM domain Peptidase_M1 PF01433.15 EPS31568.1 - 1.7e-06 27.4 0.0 0.47 9.4 0.0 3.3 2 1 1 3 3 3 3 Peptidase family M1 HEAT_2 PF13646.1 EPS31568.1 - 0.032 14.4 0.0 12 6.2 0.0 2.7 2 0 0 2 2 2 0 HEAT repeats CDP-OH_P_transf PF01066.16 EPS31569.1 - 2.2e-17 63.2 2.7 2.2e-17 63.2 1.8 2.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase ABC_tran PF00005.22 EPS31570.1 - 1.4e-42 145.2 0.0 3.6e-23 82.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EPS31570.1 - 3.8e-33 115.0 24.9 1.1e-28 100.4 7.0 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EPS31570.1 - 2.1e-12 46.7 1.7 0.013 14.7 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EPS31570.1 - 4.9e-11 43.1 5.2 0.0005 20.1 0.0 4.3 3 1 0 3 3 3 3 AAA domain T2SE PF00437.15 EPS31570.1 - 3.3e-06 26.2 0.0 0.015 14.2 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_22 PF13401.1 EPS31570.1 - 4.4e-06 26.8 1.0 0.14 12.2 0.0 3.4 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EPS31570.1 - 4.5e-06 26.0 0.6 0.02 14.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EPS31570.1 - 6.1e-06 27.0 0.5 0.17 12.7 0.0 3.0 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 EPS31570.1 - 6.4e-06 25.9 0.2 0.037 13.7 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EPS31570.1 - 1.2e-05 25.4 0.0 0.052 13.5 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.1 EPS31570.1 - 2.3e-05 24.3 0.4 0.26 11.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EPS31570.1 - 5.3e-05 22.4 0.1 0.11 11.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 EPS31570.1 - 5.4e-05 23.6 0.1 0.057 13.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 EPS31570.1 - 7.9e-05 23.1 0.1 0.54 10.7 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_10 PF12846.2 EPS31570.1 - 0.00042 19.8 0.1 0.23 10.8 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain Dynamin_N PF00350.18 EPS31570.1 - 0.00081 19.2 2.4 0.018 14.8 0.2 2.4 2 0 0 2 2 2 1 Dynamin family IstB_IS21 PF01695.12 EPS31570.1 - 0.0012 18.3 2.1 1.1 8.6 0.0 3.1 3 0 0 3 3 3 2 IstB-like ATP binding protein Zeta_toxin PF06414.7 EPS31570.1 - 0.0014 17.7 0.3 0.81 8.7 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin FtsK_SpoIIIE PF01580.13 EPS31570.1 - 0.0015 18.0 0.0 0.91 8.9 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_25 PF13481.1 EPS31570.1 - 0.0017 17.8 0.1 0.33 10.3 0.0 2.7 3 0 0 3 3 2 1 AAA domain Arch_ATPase PF01637.13 EPS31570.1 - 0.0024 17.5 0.6 0.38 10.4 0.0 3.1 3 0 0 3 3 3 1 Archaeal ATPase AAA_18 PF13238.1 EPS31570.1 - 0.0039 17.4 1.6 2.1 8.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain ATP_bind_1 PF03029.12 EPS31570.1 - 0.0058 16.1 0.9 2.5 7.5 0.1 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 EPS31570.1 - 0.0063 16.1 0.7 1.4 8.4 0.1 2.4 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EPS31570.1 - 0.0083 15.5 1.6 0.19 11.1 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 EPS31570.1 - 0.014 15.0 0.3 4.4 6.9 0.0 3.0 2 0 0 2 2 2 0 NACHT domain PRK PF00485.13 EPS31570.1 - 0.019 14.5 0.4 0.52 9.8 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family UPF0079 PF02367.12 EPS31570.1 - 0.022 14.3 0.5 0.54 9.9 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 SbcCD_C PF13558.1 EPS31570.1 - 0.022 14.6 0.2 6.9 6.6 0.0 2.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA PF00004.24 EPS31570.1 - 0.023 14.8 0.4 11 6.2 0.1 3.4 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EPS31570.1 - 0.029 13.9 0.1 3.8 7.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EPS31570.1 - 0.032 14.1 0.0 1.5 8.7 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_19 PF13245.1 EPS31570.1 - 0.038 13.7 0.2 15 5.4 0.0 2.9 2 0 0 2 2 2 0 Part of AAA domain NB-ARC PF00931.17 EPS31570.1 - 0.056 12.2 0.2 0.45 9.3 0.0 2.5 2 1 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.10 EPS31570.1 - 0.082 12.6 1.1 8.6 6.0 0.0 2.9 3 0 0 3 3 2 0 NTPase MMR_HSR1 PF01926.18 EPS31570.1 - 0.091 12.7 0.3 2.3 8.2 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Pox_A32 PF04665.7 EPS31570.1 - 0.14 11.4 0.3 1.7 7.9 0.0 2.2 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_PrkA PF08298.6 EPS31570.1 - 0.31 9.6 0.4 0.57 8.8 0.0 1.5 2 0 0 2 2 1 0 PrkA AAA domain Glyco_transf_54 PF04666.8 EPS31571.1 - 0.091 11.4 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region DNA_pol_viral_N PF00242.12 EPS31572.1 - 0.43 9.5 6.3 0.52 9.2 4.4 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Macoilin PF09726.4 EPS31572.1 - 3.2 5.9 8.0 3.1 5.9 5.6 1.1 1 0 0 1 1 1 0 Transmembrane protein SOG2 PF10428.4 EPS31572.1 - 4.7 5.7 12.1 5.3 5.5 8.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Peptidase_S64 PF08192.6 EPS31572.1 - 6.4 4.9 6.8 7.5 4.7 4.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 MS_channel PF00924.13 EPS31573.1 - 5e-23 81.5 1.6 9.2e-23 80.6 1.1 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EPS31573.1 - 0.0002 20.4 0.2 0.0005 19.1 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EPS31573.1 - 0.00049 20.1 0.1 0.0012 18.8 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 EPS31573.1 - 0.002 17.3 0.0 0.0045 16.2 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EPS31573.1 - 0.0035 17.1 0.0 0.0084 15.9 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain DUF4066 PF13278.1 EPS31574.1 - 0.019 14.2 0.1 0.021 14.0 0.0 1.1 1 0 0 1 1 1 0 Putative amidotransferase Pkinase PF00069.20 EPS31576.1 - 2.3e-59 200.6 0.0 4.7e-39 134.0 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPS31576.1 - 6.6e-28 97.4 0.0 4.6e-20 71.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 EPS31576.1 - 2.5e-11 43.5 0.0 5.9e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 EPS31576.1 - 1.2e-07 31.0 0.0 4.6e-06 25.8 0.0 2.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EPS31576.1 - 9.2e-06 25.5 0.0 0.0058 16.3 0.1 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EPS31576.1 - 0.0056 15.7 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS PF00989.19 EPS31576.1 - 0.041 13.6 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 PAS fold Seadorna_VP7 PF07387.6 EPS31576.1 - 0.097 11.4 0.1 0.17 10.6 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 GMC_oxred_N PF00732.14 EPS31577.1 - 2.6e-39 135.1 0.0 6.1e-39 133.9 0.0 1.6 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EPS31577.1 - 5.1e-38 130.6 0.0 7.8e-38 130.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EPS31577.1 - 9.1e-09 34.6 1.2 3.1e-07 29.6 0.1 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPS31577.1 - 4.7e-07 29.0 1.4 5e-05 22.3 0.8 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EPS31577.1 - 4.6e-05 22.5 0.2 0.00036 19.5 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EPS31577.1 - 7.6e-05 22.6 0.4 0.00015 21.7 0.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPS31577.1 - 0.00075 19.4 2.2 0.0035 17.3 1.5 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EPS31577.1 - 0.0011 19.0 0.3 0.03 14.4 0.3 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPS31577.1 - 0.0015 17.7 0.2 0.0024 17.0 0.1 1.2 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EPS31577.1 - 0.0015 17.0 0.2 0.0022 16.5 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 EPS31577.1 - 0.0046 15.8 1.5 0.0076 15.1 1.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 EPS31577.1 - 0.0049 17.2 2.5 0.0059 16.9 0.7 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EPS31577.1 - 0.01 14.9 2.4 0.022 13.8 1.7 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EPS31577.1 - 0.035 13.1 0.3 0.058 12.4 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 EPS31577.1 - 0.13 11.8 0.7 0.25 10.9 0.5 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 EPS31577.1 - 0.16 10.5 1.7 0.25 9.9 1.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Sugar_tr PF00083.19 EPS31578.1 - 5e-104 348.3 22.0 5.7e-104 348.2 15.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS31578.1 - 4.8e-25 88.0 22.1 4e-24 84.9 9.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EPS31578.1 - 2.7e-07 29.3 27.2 1.7e-06 26.6 0.3 3.5 3 1 1 4 4 4 3 MFS/sugar transport protein UNC-93 PF05978.11 EPS31578.1 - 3.7 7.0 13.6 1.7 8.1 0.6 3.0 3 0 0 3 3 3 0 Ion channel regulatory protein UNC-93 3Beta_HSD PF01073.14 EPS31579.1 - 5.4e-47 159.8 0.0 3.1e-42 144.2 0.0 2.0 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EPS31579.1 - 2.1e-24 86.2 0.0 5.8e-24 84.8 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EPS31579.1 - 3.7e-14 52.2 0.0 1.7e-13 50.0 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 EPS31579.1 - 6.7e-08 31.7 0.2 4.7e-07 28.9 0.1 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EPS31579.1 - 0.00015 21.8 0.0 0.0024 17.9 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding adh_short PF00106.20 EPS31579.1 - 0.056 13.3 0.1 5.3 6.9 0.0 2.6 2 1 0 2 2 2 0 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EPS31579.1 - 0.11 11.3 0.0 0.64 8.8 0.0 2.1 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein KR PF08659.5 EPS31579.1 - 0.14 11.7 0.1 1.5 8.4 0.1 2.6 1 1 0 1 1 1 0 KR domain UQ_con PF00179.21 EPS31580.1 - 1.7e-33 114.9 0.1 1.6e-13 50.2 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin-conjugating enzyme UEV PF05743.8 EPS31580.1 - 0.00039 20.0 0.1 0.017 14.8 0.0 2.5 2 0 0 2 2 2 1 UEV domain Prok-E2_B PF14461.1 EPS31580.1 - 0.019 14.7 0.0 0.085 12.6 0.0 2.1 2 0 0 2 2 2 0 Prokaryotic E2 family B RhoGAP PF00620.22 EPS31582.1 - 4.4e-36 123.7 0.1 8.7e-36 122.8 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 EPS31582.1 - 4.9e-26 90.5 45.6 4.1e-12 45.9 4.1 4.7 5 0 0 5 5 5 4 LIM domain Nbl1_Borealin_N PF10444.4 EPS31584.1 - 6.4e-21 73.4 2.5 1.1e-20 72.7 1.7 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal VWA_2 PF13519.1 EPS31585.1 - 1e-11 45.2 0.2 1.1e-11 45.1 0.2 1.2 1 1 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 EPS31585.1 - 3.2e-05 23.5 0.1 4.5e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.23 EPS31585.1 - 0.00075 19.2 0.1 0.0012 18.5 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.15 EPS31585.1 - 0.0028 17.0 0.6 0.011 15.1 0.4 2.2 1 0 0 1 1 1 1 Ubiquitin interaction motif DUF4097 PF13349.1 EPS31585.1 - 0.05 13.1 0.6 0.085 12.4 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) Sybindin PF04099.7 EPS31586.1 - 1.8e-46 157.4 0.0 2.6e-46 156.8 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EPS31586.1 - 1.5e-08 34.5 0.0 2.3e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region ABC2_membrane PF01061.19 EPS31587.1 - 3.3e-96 320.4 60.7 1.6e-48 164.6 17.1 2.5 2 0 0 2 2 2 2 ABC-2 type transporter PDR_CDR PF06422.7 EPS31587.1 - 7.8e-36 121.8 2.8 3.3e-32 110.1 0.0 3.5 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.22 EPS31587.1 - 1e-34 119.7 0.0 3.7e-16 59.6 0.0 3.4 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.1 EPS31587.1 - 4.2e-23 81.2 0.2 1.4e-22 79.5 0.1 1.9 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 EPS31587.1 - 1e-06 28.0 13.3 1e-06 28.0 9.2 3.3 3 0 0 3 3 3 1 ABC-2 family transporter protein AAA_25 PF13481.1 EPS31587.1 - 4e-06 26.3 0.1 0.0011 18.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EPS31587.1 - 0.00012 21.5 1.0 0.0016 17.9 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EPS31587.1 - 0.00044 20.1 0.0 0.054 13.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EPS31587.1 - 0.00056 19.1 0.0 0.057 12.5 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EPS31587.1 - 0.0011 18.4 0.3 0.094 12.2 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 EPS31587.1 - 0.0036 17.6 0.0 0.053 13.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EPS31587.1 - 0.0098 16.0 0.1 2.4 8.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EPS31587.1 - 0.013 15.1 3.6 2.2 7.8 0.1 3.9 4 0 0 4 4 4 0 NACHT domain AAA_16 PF13191.1 EPS31587.1 - 0.015 15.2 0.2 0.46 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 EPS31587.1 - 0.016 14.9 0.2 2.3 8.0 0.1 2.5 2 0 0 2 2 2 0 Part of AAA domain AAA_17 PF13207.1 EPS31587.1 - 0.037 14.8 0.0 0.37 11.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EPS31587.1 - 0.041 13.3 0.1 0.5 9.7 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family SMC_N PF02463.14 EPS31587.1 - 0.076 12.2 0.0 1.6 7.9 0.0 2.5 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EPS31587.1 - 0.25 11.6 0.1 0.49 10.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EPS31587.1 - 0.31 9.8 0.2 15 4.3 0.1 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein UPF0079 PF02367.12 EPS31587.1 - 0.35 10.5 1.1 4.1 7.0 0.3 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 SspO PF08175.7 EPS31588.1 - 0.014 15.7 0.3 0.019 15.2 0.2 1.3 1 1 0 1 1 1 0 Small acid-soluble spore protein O family DUF3340 PF11818.3 EPS31590.1 - 0.051 13.5 1.5 0.1 12.5 1.0 1.5 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) Atrophin-1 PF03154.10 EPS31590.1 - 1 7.4 4.9 1.2 7.1 3.4 1.1 1 0 0 1 1 1 0 Atrophin-1 family Alpha-L-AF_C PF06964.7 EPS31591.1 - 7.7e-37 126.7 0.1 1.4e-36 125.9 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus HCV_NS5a_C PF12941.2 EPS31593.1 - 3.8 7.0 8.4 4.2 6.8 5.8 1.1 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region F-box PF00646.28 EPS31600.1 - 5e-07 29.2 4.8 3.5e-05 23.3 0.1 3.4 3 0 0 3 3 3 2 F-box domain F-box-like PF12937.2 EPS31600.1 - 0.033 13.9 0.7 0.033 13.9 0.5 2.3 2 0 0 2 2 2 0 F-box-like SH3BGR PF04908.10 EPS31601.1 - 0.0005 19.9 0.1 0.0015 18.4 0.0 1.9 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein Ribul_P_3_epim PF00834.14 EPS31602.1 - 1.3e-62 210.4 0.0 1.9e-61 206.7 0.0 2.1 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family ThiG PF05690.9 EPS31602.1 - 0.063 12.3 0.1 0.091 11.8 0.1 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Amidohydro_2 PF04909.9 EPS31602.1 - 0.065 12.7 0.2 2 7.9 0.0 2.4 1 1 1 2 2 2 0 Amidohydrolase OMPdecase PF00215.19 EPS31602.1 - 0.068 12.5 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Methyltransf_11 PF08241.7 EPS31603.1 - 3.4e-06 27.4 0.0 6.9e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPS31603.1 - 0.016 14.8 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain LSM PF01423.17 EPS31604.1 - 5.8e-15 54.5 0.6 8e-15 54.1 0.4 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EPS31604.1 - 0.041 13.7 0.0 0.056 13.3 0.0 1.3 1 1 0 1 1 1 0 Ataxin 2 SM domain NTP_transf_2 PF01909.18 EPS31604.1 - 0.056 13.7 0.0 0.1 12.9 0.0 1.4 1 1 0 1 1 1 0 Nucleotidyltransferase domain DRMBL PF07522.9 EPS31605.1 - 4e-33 113.7 0.0 7.7e-33 112.8 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EPS31605.1 - 4e-09 36.2 0.0 7.7e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain p450 PF00067.17 EPS31606.1 - 2.1e-99 333.1 0.0 2.5e-99 332.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 OPT PF03169.10 EPS31607.1 - 1.5e-187 624.8 54.6 1.7e-187 624.6 37.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF754 PF05449.6 EPS31607.1 - 0.85 9.6 6.5 0.2 11.7 1.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF754) DUF3295 PF11702.3 EPS31609.1 - 0.51 9.2 1.7 1 8.2 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3295) Glyco_hydro_18 PF00704.23 EPS31611.1 - 6.3e-73 246.1 0.9 6.3e-73 246.1 0.6 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EPS31611.1 - 5.5e-10 39.0 18.8 5.5e-10 39.0 13.0 4.3 4 0 0 4 4 4 2 Chitin recognition protein DNase_NucA_NucB PF14040.1 EPS31611.1 - 0.00073 19.6 0.2 0.011 15.8 0.1 2.6 2 0 0 2 2 2 1 Deoxyribonuclease NucA/NucB Chitin_bind_1 PF00187.14 EPS31612.1 - 2.4e-11 43.4 81.2 0.00012 21.9 16.6 5.0 4 1 0 4 4 4 3 Chitin recognition protein LysM PF01476.15 EPS31612.1 - 8.9e-09 35.1 0.5 0.0053 16.6 0.0 2.9 3 0 0 3 3 3 2 LysM domain DNA_pol_A_exo1 PF01612.15 EPS31613.1 - 3.6e-10 39.5 0.0 1.8e-09 37.3 0.0 1.9 1 1 0 1 1 1 1 3'-5' exonuclease DNA_pol_B_2 PF03175.8 EPS31613.1 - 0.034 12.8 0.0 0.055 12.1 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral SMP PF04927.7 EPS31614.1 - 2.5e-12 46.5 7.2 4.8e-06 26.4 0.7 3.2 2 1 1 3 3 3 3 Seed maturation protein GFA PF04828.9 EPS31616.1 - 5.6e-23 80.7 0.0 8e-23 80.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Yippee-Mis18 PF03226.9 EPS31616.1 - 0.11 12.5 0.2 0.37 10.8 0.1 2.0 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Nudix_N_2 PF14803.1 EPS31616.1 - 0.13 11.9 0.1 0.13 11.9 0.0 2.6 3 0 0 3 3 3 0 Nudix N-terminal zinc_ribbon_2 PF13240.1 EPS31616.1 - 0.16 11.4 1.1 0.3 10.6 0.1 2.0 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 EPS31616.1 - 0.51 10.2 3.7 7.4 6.4 2.9 2.4 1 1 1 2 2 2 0 Double zinc ribbon Zn_clus PF00172.13 EPS31617.1 - 5.3e-09 35.8 10.1 1.6e-08 34.2 7.0 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HSDR_N_2 PF13588.1 EPS31619.1 - 0.0011 18.7 0.1 0.0023 17.7 0.1 1.6 1 1 0 1 1 1 1 Type I restriction enzyme R protein N terminus (HSDR_N) ATG22 PF11700.3 EPS31620.1 - 1.2e-181 604.3 13.3 1.4e-181 604.1 9.2 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EPS31620.1 - 9.6e-08 31.1 40.9 1.7e-07 30.2 12.1 2.8 3 0 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS31621.1 - 1.2e-80 271.3 24.1 1.4e-80 271.0 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS31621.1 - 1.4e-24 86.5 31.9 1.8e-21 76.2 17.2 2.6 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 EPS31621.1 - 3.9e-05 22.2 18.1 0.00048 18.6 5.7 3.4 3 1 1 4 4 4 2 MFS/sugar transport protein DUF735 PF05246.6 EPS31622.1 - 0.016 14.9 0.1 0.022 14.5 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF735) Glyco_hydro_57 PF03065.10 EPS31622.1 - 0.091 11.6 0.1 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 57 DUF2654 PF10849.3 EPS31622.1 - 0.1 12.3 0.2 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2654) DDE_1 PF03184.14 EPS31623.1 - 2.6e-18 65.9 0.0 4.7e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EPS31623.1 - 5.5e-12 45.3 2.8 8.7e-12 44.6 0.2 2.5 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain HTH_psq PF05225.11 EPS31623.1 - 2.5e-06 26.9 0.4 2.5e-06 26.9 0.3 2.2 2 0 0 2 2 2 1 helix-turn-helix, Psq domain HTH_28 PF13518.1 EPS31623.1 - 0.0053 16.7 0.6 0.051 13.5 0.1 2.7 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.1 EPS31623.1 - 0.089 13.5 1.4 0.21 12.3 0.3 2.3 2 0 0 2 2 2 0 Homeodomain-like domain HTH_Tnp_1 PF01527.15 EPS31623.1 - 0.11 12.5 0.1 3.7 7.5 0.0 3.0 3 0 0 3 3 3 0 Transposase DUF4418 PF14387.1 EPS31625.1 - 0.67 9.7 9.1 0.22 11.2 4.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4418) TPR_12 PF13424.1 EPS31628.1 - 8.8e-67 221.0 5.0 5.7e-17 61.4 0.0 5.1 3 1 2 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.1 EPS31628.1 - 2.4e-64 211.5 0.1 5.6e-11 42.0 0.0 7.8 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_1 PF00515.23 EPS31628.1 - 3.8e-35 118.0 16.8 2.2e-05 23.8 0.9 7.8 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.1 EPS31628.1 - 2.6e-33 113.4 23.4 3.8e-09 36.0 0.6 5.8 2 2 4 6 6 6 6 TPR repeat TPR_7 PF13176.1 EPS31628.1 - 8.6e-32 106.4 15.2 1.7e-05 24.2 0.0 9.4 10 0 0 10 10 8 7 Tetratricopeptide repeat TPR_2 PF07719.12 EPS31628.1 - 1.2e-24 84.1 15.2 0.0018 18.0 0.3 8.6 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.1 EPS31628.1 - 1.7e-20 71.6 8.2 0.16 12.6 0.0 8.9 5 2 3 8 8 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 EPS31628.1 - 1.7e-13 49.3 13.7 0.083 12.7 0.0 7.7 8 0 0 8 8 7 4 Tetratricopeptide repeat NB-ARC PF00931.17 EPS31628.1 - 1.2e-12 47.3 0.0 2.2e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain TPR_16 PF13432.1 EPS31628.1 - 2.3e-11 44.0 16.8 9.3e-06 26.1 0.1 6.5 6 3 0 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 EPS31628.1 - 6.8e-09 35.2 3.7 2.3 8.6 0.1 6.7 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 EPS31628.1 - 4.7e-08 33.2 7.7 0.11 12.8 0.2 5.9 4 2 1 5 5 5 2 Tetratricopeptide repeat 14-3-3 PF00244.15 EPS31628.1 - 1.1e-07 31.2 0.5 0.27 10.2 0.0 4.5 2 1 3 5 5 5 2 14-3-3 protein DUF2225 PF09986.4 EPS31628.1 - 3.9e-06 26.4 0.2 0.19 11.1 0.0 3.6 1 1 1 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) TPR_6 PF13174.1 EPS31628.1 - 7.9e-06 25.9 22.4 0.56 10.7 0.2 8.2 8 0 0 8 8 8 1 Tetratricopeptide repeat AAA_16 PF13191.1 EPS31628.1 - 2.1e-05 24.6 1.1 0.00013 21.9 0.6 2.7 1 1 0 1 1 1 1 AAA ATPase domain TPR_4 PF07721.9 EPS31628.1 - 2.3e-05 24.3 2.4 2.9 8.5 0.0 5.2 5 0 0 5 5 3 1 Tetratricopeptide repeat Tcf25 PF04910.9 EPS31628.1 - 2.6e-05 23.3 0.4 15 4.3 0.0 5.6 1 1 6 7 7 7 0 Transcriptional repressor TCF25 Apc3 PF12895.2 EPS31628.1 - 5.5e-05 23.2 0.1 1 9.5 0.0 4.0 1 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 PNP_UDP_1 PF01048.15 EPS31628.1 - 5.5e-05 22.2 0.1 0.00017 20.6 0.1 1.8 1 1 0 1 1 1 1 Phosphorylase superfamily SPO22 PF08631.5 EPS31628.1 - 0.0012 18.0 0.1 3 6.8 0.0 3.9 3 1 1 4 4 4 1 Meiosis protein SPO22/ZIP4 like Arch_ATPase PF01637.13 EPS31628.1 - 0.0041 16.8 0.0 0.0092 15.7 0.0 1.6 1 1 0 1 1 1 1 Archaeal ATPase RPN7 PF10602.4 EPS31628.1 - 0.0063 15.9 0.4 21 4.4 0.0 4.0 1 1 3 4 4 4 0 26S proteasome subunit RPN7 TPR_21 PF09976.4 EPS31628.1 - 0.0072 16.2 2.0 23 4.9 0.0 4.5 3 1 0 3 3 3 0 Tetratricopeptide repeat Ubiq_cyt_C_chap PF03981.7 EPS31628.1 - 0.073 12.9 0.1 0.91 9.3 0.0 2.5 1 1 1 2 2 2 0 Ubiquinol-cytochrome C chaperone TPR_3 PF07720.7 EPS31628.1 - 1.3 8.8 12.1 0.27 11.0 0.2 5.1 7 0 0 7 7 6 0 Tetratricopeptide repeat Nucleo_P87 PF07267.6 EPS31630.1 - 0.34 9.5 7.5 0.46 9.1 5.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 adh_short_C2 PF13561.1 EPS31631.1 - 1.2e-29 103.7 0.0 1.4e-29 103.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EPS31631.1 - 4.5e-29 101.5 0.2 5.6e-29 101.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPS31631.1 - 3.2e-16 59.5 0.1 4.4e-16 59.0 0.1 1.1 1 0 0 1 1 1 1 KR domain MFS_1 PF07690.11 EPS31635.1 - 3.8e-28 98.2 38.8 5.9e-27 94.3 22.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EPS31635.1 - 4e-05 22.0 2.5 6.9e-05 21.2 1.7 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1275 PF06912.6 EPS31636.1 - 4.6e-37 127.2 16.0 5.6e-37 126.9 11.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Sulfate_transp PF00916.15 EPS31636.1 - 0.011 14.8 0.3 0.016 14.2 0.2 1.4 1 0 0 1 1 1 0 Sulfate transporter family 7TMR-DISM_7TM PF07695.6 EPS31636.1 - 0.15 11.7 11.5 0.026 14.1 2.3 2.2 1 1 1 2 2 2 0 7TM diverse intracellular signalling GCV_T_C PF08669.6 EPS31637.1 - 0.066 13.2 0.2 0.17 11.9 0.1 1.9 1 1 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain zf-CCHC_4 PF14392.1 EPS31639.1 - 0.017 14.7 3.6 0.032 13.8 2.5 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 EPS31639.1 - 0.23 11.4 5.7 0.39 10.7 3.9 1.4 1 0 0 1 1 1 0 Zinc knuckle Cupin_1 PF00190.17 EPS31640.1 - 1.9e-31 108.4 0.0 2.1e-15 56.4 0.0 2.1 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EPS31640.1 - 1.1e-23 82.5 0.5 6.8e-11 41.5 0.1 2.5 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EPS31640.1 - 2e-10 39.9 0.0 7.6e-06 25.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 EPS31640.1 - 2.9e-06 27.0 0.1 0.0028 17.3 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_6 PF12852.2 EPS31640.1 - 0.00068 19.2 0.0 0.47 10.0 0.0 2.5 1 1 0 2 2 2 2 Cupin CENP-C_C PF11699.3 EPS31640.1 - 0.14 12.1 0.0 5.2 7.1 0.0 2.9 3 0 0 3 3 3 0 Mif2/CENP-C like Peptidase_M50B PF13398.1 EPS31641.1 - 1.8e-56 190.7 22.3 2.2e-56 190.4 15.4 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.17 EPS31641.1 - 0.0039 16.1 0.3 0.0039 16.1 0.2 2.7 2 1 1 3 3 3 1 Peptidase family M50 Peptidase_M41 PF01434.13 EPS31641.1 - 0.13 11.6 0.1 0.2 11.1 0.1 1.2 1 0 0 1 1 1 0 Peptidase family M41 Patched PF02460.13 EPS31641.1 - 1.3 6.8 6.7 2.3 6.0 4.6 1.3 1 0 0 1 1 1 0 Patched family UbiA PF01040.13 EPS31641.1 - 4 6.5 21.9 1 8.5 9.9 2.1 2 0 0 2 2 2 0 UbiA prenyltransferase family YlaC PF10777.4 EPS31641.1 - 6.5 6.3 6.3 0.58 9.6 0.7 1.9 2 0 0 2 2 2 0 Inner membrane protein YlaC RTA1 PF04479.8 EPS31642.1 - 1.4e-39 135.9 10.5 2e-39 135.3 7.3 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF373 PF04123.8 EPS31642.1 - 4.1 6.3 12.9 2.7 6.9 5.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF373) DUF3098 PF11297.3 EPS31642.1 - 10 5.9 11.0 0.15 11.7 1.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3098) UDPGT PF00201.13 EPS31645.1 - 2.4e-07 29.6 0.0 4.1e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase UIM PF02809.15 EPS31645.1 - 4.2e-05 22.7 0.9 0.00014 21.1 0.6 2.0 1 0 0 1 1 1 1 Ubiquitin interaction motif Glyco_tran_28_C PF04101.11 EPS31645.1 - 0.0023 17.6 0.0 0.0068 16.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain DUF2701 PF10857.3 EPS31645.1 - 0.16 11.7 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2701) rve PF00665.21 EPS31647.1 - 5e-10 39.5 0.1 9e-10 38.7 0.1 1.4 1 0 0 1 1 1 1 Integrase core domain RVT_2 PF07727.9 EPS31648.1 - 1.3e-25 89.8 0.0 2.1e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cons_hypoth95 PF03602.10 EPS31652.1 - 0.041 13.2 0.0 0.055 12.8 0.0 1.1 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Pkinase PF00069.20 EPS31654.1 - 1.3e-34 119.5 0.1 1.4e-31 109.5 0.1 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPS31654.1 - 1.2e-13 50.7 0.0 1.7e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPS31654.1 - 2.1e-07 30.9 0.0 0.0046 16.7 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EPS31654.1 - 2.6e-06 26.6 0.0 4e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EPS31654.1 - 0.0035 16.9 1.6 0.015 14.8 0.6 2.0 1 1 1 2 2 2 1 Choline/ethanolamine kinase RIO1 PF01163.17 EPS31654.1 - 0.0073 15.6 3.5 0.023 14.0 2.0 1.9 1 1 0 1 1 1 1 RIO1 family Phage_Gp15 PF06854.6 EPS31654.1 - 0.044 13.3 0.2 0.061 12.8 0.1 1.1 1 0 0 1 1 1 0 Bacteriophage Gp15 protein Kinase-like PF14531.1 EPS31654.1 - 0.098 11.6 0.0 0.18 10.7 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Toxin_39 PF15500.1 EPS31655.1 - 0.13 12.3 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 Putative RNase-like toxin 2OG-FeII_Oxy_3 PF13640.1 EPS31656.1 - 2.9e-05 24.4 0.4 0.00013 22.4 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EPS31656.1 - 0.00023 21.3 0.0 0.00044 20.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Peptidase_M3 PF01432.15 EPS31657.1 - 8.3e-110 367.9 0.0 1.1e-109 367.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.1 EPS31657.1 - 0.046 13.7 2.3 0.063 13.3 0.5 1.9 2 0 0 2 2 2 0 Effector protein Aldo_ket_red PF00248.16 EPS31658.1 - 5.7e-14 51.5 0.0 7e-14 51.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 EPS31659.1 - 1e-16 60.6 0.0 1.1e-16 60.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MIP PF00230.15 EPS31662.1 - 1.6e-45 155.3 6.3 2.1e-45 154.9 4.3 1.1 1 0 0 1 1 1 1 Major intrinsic protein OspD PF03207.8 EPS31663.1 - 0.038 13.1 0.1 0.043 12.9 0.0 1.1 1 0 0 1 1 1 0 Borrelia outer surface protein D (OspD) ORC6 PF05460.8 EPS31663.1 - 0.11 11.5 3.4 0.14 11.2 2.4 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) BDM PF10684.4 EPS31663.1 - 0.14 12.3 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative biofilm-dependent modulation protein CAF-1_p150 PF11600.3 EPS31663.1 - 0.19 11.1 11.3 0.22 10.8 7.8 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF737 PF05300.6 EPS31663.1 - 0.4 10.6 10.3 0.49 10.3 7.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Birna_VP3 PF01767.11 EPS31663.1 - 1.4 8.4 5.6 1.7 8.2 3.4 1.4 1 1 0 1 1 1 0 Birnavirus VP3 protein Period_C PF12114.3 EPS31663.1 - 2.2 7.8 9.5 2.8 7.4 6.6 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Glyco_hydro_71 PF03659.9 EPS31664.1 - 1.4e-141 471.4 1.1 1.4e-141 471.4 0.8 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 71 Telomere_Sde2 PF13019.1 EPS31664.1 - 8.7 6.0 6.0 15 5.2 4.1 1.3 1 0 0 1 1 1 0 Telomere stability and silencing ADH_N PF08240.7 EPS31666.1 - 1.3e-23 82.8 0.1 2.3e-23 82.0 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPS31666.1 - 7.3e-18 64.3 0.0 1e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF3433 PF11915.3 EPS31667.1 - 5.9e-44 148.1 22.9 1e-23 83.2 2.4 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) Pyr_redox_2 PF07992.9 EPS31668.1 - 5.1e-11 42.8 0.0 8.5e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EPS31668.1 - 0.00054 18.9 0.0 0.13 11.1 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EPS31668.1 - 0.0048 16.6 0.1 3 7.5 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding HI0933_like PF03486.9 EPS31668.1 - 0.02 13.3 0.0 0.048 12.1 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 EPS31668.1 - 0.032 13.3 0.0 0.059 12.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.17 EPS31668.1 - 0.04 12.7 0.0 4.6 5.9 0.0 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EPS31668.1 - 0.048 13.7 0.2 21 5.1 0.0 3.1 2 2 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_2 PF00891.13 EPS31670.1 - 2.3e-28 99.0 0.0 3.4e-28 98.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 EPS31670.1 - 0.13 12.0 2.5 0.28 11.0 0.5 2.6 2 2 0 2 2 2 0 Dimerisation domain AP_endonuc_2 PF01261.19 EPS31671.1 - 7.2e-24 84.2 0.3 1e-23 83.7 0.2 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel AMP-binding PF00501.23 EPS31673.1 - 3.1e-35 121.3 0.0 6.9e-35 120.2 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EPS31673.1 - 2.2e-30 105.4 0.0 3.3e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EPS31673.1 - 3.2e-13 49.6 0.0 5.1e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EPS31673.1 - 4.5e-05 23.6 0.1 0.0001 22.4 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.5 EPS31673.1 - 0.0041 16.8 0.1 0.029 14.0 0.1 2.2 1 1 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 EPS31673.1 - 0.015 14.2 0.0 1.4 7.7 0.0 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EPS31673.1 - 0.018 13.9 0.0 0.033 13.0 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DapB_N PF01113.15 EPS31673.1 - 0.018 14.9 0.0 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus NmrA PF05368.8 EPS31673.1 - 0.029 13.6 0.0 0.047 12.9 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family Saccharop_dh PF03435.13 EPS31673.1 - 0.029 13.3 0.0 0.043 12.7 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase adh_short PF00106.20 EPS31673.1 - 0.032 14.1 0.2 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 short chain dehydrogenase STAT6_C PF14596.1 EPS31673.1 - 0.041 13.8 0.0 0.085 12.7 0.0 1.4 1 0 0 1 1 1 0 STAT6 C-terminal Semialdhyde_dh PF01118.19 EPS31673.1 - 0.052 13.8 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Hemerythrin PF01814.18 EPS31676.1 - 2.2e-12 47.3 0.6 2.9e-12 46.8 0.4 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Zn_clus PF00172.13 EPS31678.1 - 0.0003 20.6 7.9 0.00055 19.7 5.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HypA PF01155.14 EPS31678.1 - 0.25 11.0 1.7 0.41 10.3 1.2 1.3 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family AAA_17 PF13207.1 EPS31679.1 - 7.1e-07 30.0 0.0 3.1e-06 27.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPS31679.1 - 1.3e-06 28.7 0.0 1.2e-05 25.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 EPS31679.1 - 1.7e-06 27.7 0.0 1.2e-05 24.9 0.0 2.0 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.1 EPS31679.1 - 7.5e-06 25.8 0.0 0.00069 19.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EPS31679.1 - 2.5e-05 24.3 0.0 4.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EPS31679.1 - 9.3e-05 22.1 0.1 0.0002 21.0 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 EPS31679.1 - 0.00013 21.1 1.1 0.00036 19.6 0.3 2.1 2 1 1 3 3 3 1 Zeta toxin AAA_22 PF13401.1 EPS31679.1 - 0.00019 21.5 0.0 0.00036 20.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EPS31679.1 - 0.00045 20.4 0.0 0.00066 19.8 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EPS31679.1 - 0.0013 18.4 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 NACHT domain T2SE PF00437.15 EPS31679.1 - 0.0018 17.2 0.0 0.0027 16.6 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein NB-ARC PF00931.17 EPS31679.1 - 0.0022 16.9 0.0 0.0031 16.4 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain APS_kinase PF01583.15 EPS31679.1 - 0.0036 16.9 0.0 0.045 13.4 0.0 2.2 2 0 0 2 2 2 1 Adenylylsulphate kinase FtsK_SpoIIIE PF01580.13 EPS31679.1 - 0.0042 16.5 0.1 0.0062 16.0 0.0 1.4 1 1 0 1 1 1 1 FtsK/SpoIIIE family AAA_30 PF13604.1 EPS31679.1 - 0.005 16.4 0.1 0.01 15.4 0.1 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EPS31679.1 - 0.0059 15.8 0.0 0.009 15.2 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_11 PF13086.1 EPS31679.1 - 0.01 15.4 0.0 0.015 14.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 EPS31679.1 - 0.011 15.4 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.13 EPS31679.1 - 0.011 15.2 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ArgK PF03308.11 EPS31679.1 - 0.016 14.0 0.0 0.024 13.4 0.0 1.2 1 0 0 1 1 1 0 ArgK protein SRP54 PF00448.17 EPS31679.1 - 0.018 14.5 0.0 0.038 13.4 0.0 1.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Thymidylate_kin PF02223.12 EPS31679.1 - 0.02 14.3 0.0 0.19 11.0 0.0 2.1 2 0 0 2 2 2 0 Thymidylate kinase NTPase_1 PF03266.10 EPS31679.1 - 0.024 14.3 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 NTPase ABC_tran PF00005.22 EPS31679.1 - 0.034 14.4 0.0 0.11 12.8 0.0 1.9 2 0 0 2 2 2 0 ABC transporter DUF2075 PF09848.4 EPS31679.1 - 0.034 13.1 0.0 0.044 12.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.1 EPS31679.1 - 0.053 13.4 0.0 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EPS31679.1 - 0.098 12.4 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 ATP_bind_1 PF03029.12 EPS31679.1 - 0.12 11.9 0.0 0.29 10.6 0.0 1.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.1 EPS31679.1 - 0.23 11.4 1.5 0.35 10.8 0.1 2.0 2 1 0 2 2 2 0 AAA domain GFA PF04828.9 EPS31680.1 - 3.8e-18 65.2 0.9 6.1e-18 64.5 0.6 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme UPF1_Zn_bind PF09416.5 EPS31680.1 - 0.0072 15.9 1.0 0.011 15.3 0.7 1.2 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) DUF512 PF04459.7 EPS31680.1 - 0.046 12.7 0.0 0.056 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF512) RNA_POL_M_15KD PF02150.11 EPS31680.1 - 0.079 12.6 4.4 3.9 7.2 0.2 2.5 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit C1_1 PF00130.17 EPS31680.1 - 0.29 10.9 4.2 5.4 6.8 0.0 2.4 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Cys_rich_CWC PF14375.1 EPS31680.1 - 0.37 10.7 6.8 0.071 13.0 2.0 1.8 2 0 0 2 2 2 0 Cysteine-rich CWC Rpr2 PF04032.11 EPS31680.1 - 0.67 9.8 4.7 2.8 7.8 0.1 2.3 1 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain FYVE PF01363.16 EPS31680.1 - 0.79 9.6 5.7 2.1 8.3 3.9 1.9 1 1 0 1 1 1 0 FYVE zinc finger IF-2B PF01008.12 EPS31681.1 - 1.8e-22 79.6 0.0 4.2e-22 78.4 0.0 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family NUDIX PF00293.23 EPS31681.1 - 4.7e-13 48.9 0.0 8.9e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Abhydrolase_6 PF12697.2 EPS31682.1 - 9.7e-23 81.2 0.1 1.3e-22 80.8 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPS31682.1 - 5.2e-22 78.5 0.0 6.7e-21 74.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPS31682.1 - 7.6e-08 32.2 0.0 1.1e-07 31.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EPS31682.1 - 0.0012 18.3 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.15 EPS31682.1 - 0.005 17.0 0.0 0.022 14.9 0.0 1.9 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.8 EPS31682.1 - 0.016 14.8 0.0 0.034 13.7 0.0 1.6 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ndr PF03096.9 EPS31682.1 - 0.024 13.1 0.0 0.2 10.1 0.0 1.9 2 0 0 2 2 2 0 Ndr family DUF915 PF06028.6 EPS31682.1 - 0.063 12.3 0.0 0.094 11.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Kinesin PF00225.18 EPS31683.1 - 4.3e-105 351.1 0.2 4.3e-105 351.1 0.2 2.6 3 0 0 3 3 3 1 Kinesin motor domain ArsR PF09824.4 EPS31683.1 - 0.055 12.7 4.6 0.59 9.4 0.0 3.1 3 0 0 3 3 3 0 ArsR transcriptional regulator Microtub_assoc PF07989.6 EPS31683.1 - 0.11 12.2 17.8 0.028 14.2 1.3 3.5 3 1 0 3 3 3 0 Microtubule associated ERM PF00769.14 EPS31683.1 - 0.91 9.0 43.2 2.4 7.6 21.8 2.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Reo_sigmaC PF04582.7 EPS31683.1 - 1 8.4 9.3 3.3 6.7 0.3 3.1 3 0 0 3 3 3 0 Reovirus sigma C capsid protein TPR_MLP1_2 PF07926.7 EPS31683.1 - 7.5 6.3 38.4 1.6 8.4 9.6 4.1 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein DUF1900 PF08954.6 EPS31685.1 - 8e-50 167.8 0.0 7.7e-49 164.7 0.0 2.4 2 1 1 3 3 3 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 EPS31685.1 - 4.3e-34 115.9 0.0 7.8e-34 115.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 EPS31685.1 - 1.2e-23 82.0 1.2 1.3e-06 28.0 0.0 4.0 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 EPS31685.1 - 0.00011 20.4 0.4 0.2 9.7 0.0 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 SlyX PF04102.7 EPS31685.1 - 0.22 11.9 2.9 0.24 11.8 0.9 1.8 2 0 0 2 2 2 0 SlyX Peptidase_C97 PF05903.9 EPS31687.1 - 0.068 12.9 0.6 0.12 12.1 0.4 1.4 1 1 0 1 1 1 0 PPPDE putative peptidase domain Dymeclin PF09742.4 EPS31688.1 - 0.07 11.2 0.4 0.078 11.0 0.2 1.0 1 0 0 1 1 1 0 Dyggve-Melchior-Clausen syndrome protein Abi PF02517.11 EPS31688.1 - 0.22 11.6 1.2 0.33 11.1 0.8 1.6 1 1 0 1 1 1 0 CAAX protease self-immunity Baculo_11_kDa PF06143.6 EPS31691.1 - 0.029 13.7 0.5 0.068 12.5 0.4 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family CBM_1 PF00734.13 EPS31692.1 - 2.8e-10 39.6 15.8 2.8e-10 39.6 10.9 3.1 3 0 0 3 3 3 1 Fungal cellulose binding domain Peptidase_S9 PF00326.16 EPS31692.1 - 1.4e-07 31.0 0.1 2.7e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EPS31692.1 - 1.2e-05 24.8 0.0 1.9e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EPS31692.1 - 4.2e-05 23.3 0.0 5.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EPS31692.1 - 0.00014 21.3 0.6 0.0004 19.8 0.4 1.7 1 1 0 1 1 1 1 Putative esterase Esterase_phd PF10503.4 EPS31692.1 - 0.00015 21.1 0.0 0.00023 20.4 0.0 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_6 PF12697.2 EPS31692.1 - 0.00016 21.6 0.0 0.00019 21.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPS31692.1 - 0.0092 15.5 0.4 0.024 14.1 0.3 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.7 EPS31692.1 - 0.2 10.0 0.0 0.29 9.5 0.0 1.1 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Rhodanese PF00581.15 EPS31693.1 - 2.4e-19 69.7 0.0 8.8e-14 51.8 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain Zn_clus PF00172.13 EPS31694.1 - 1.5e-11 43.9 7.4 3.1e-11 42.9 5.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EPS31694.1 - 5.6e-11 41.7 0.9 8.9e-11 41.1 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Metallophos PF00149.23 EPS31695.1 - 1e-05 25.0 1.6 2.7e-05 23.6 1.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EPS31695.1 - 0.001 18.8 0.1 0.0019 18.0 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Elicitin PF00964.12 EPS31695.1 - 0.009 15.9 2.9 0.54 10.2 0.1 2.3 2 0 0 2 2 2 2 Elicitin zf-C3HC4_3 PF13920.1 EPS31696.1 - 0.00083 18.9 11.8 0.0013 18.3 8.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPS31696.1 - 0.51 10.4 13.3 0.81 9.7 9.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPS31696.1 - 6.3 6.6 12.9 9.9 5.9 8.9 1.3 1 0 0 1 1 1 0 zinc-RING finger domain CBFD_NFYB_HMF PF00808.18 EPS31697.1 - 1.6e-15 56.9 2.4 2.5e-15 56.2 1.7 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EPS31697.1 - 9.4e-08 32.0 0.9 1.6e-07 31.3 0.6 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 RAI16-like PF10257.4 EPS31698.1 - 5.9e-87 291.8 0.0 9.7e-87 291.1 0.0 1.3 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein MFS_1 PF07690.11 EPS31699.1 - 1.8e-15 56.5 22.3 1.8e-15 56.5 15.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF202 PF02656.10 EPS31699.1 - 0.36 11.0 0.1 0.36 11.0 0.0 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF202) Acyltransferase PF01553.16 EPS31700.1 - 0.0046 16.3 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase ILVD_EDD PF00920.16 EPS31701.1 - 1.7e-201 670.2 0.9 2e-201 669.9 0.6 1.0 1 0 0 1 1 1 1 Dehydratase family 5_nucleotid_C PF02872.13 EPS31701.1 - 0.11 12.5 0.0 0.42 10.5 0.0 2.0 2 0 0 2 2 2 0 5'-nucleotidase, C-terminal domain Pkinase PF00069.20 EPS31702.1 - 3.3e-47 160.8 0.0 2.3e-46 158.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS31702.1 - 5.2e-27 94.5 0.0 8.7e-27 93.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPS31702.1 - 0.0013 17.7 0.0 0.0031 16.5 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Fungal_trans_2 PF11951.3 EPS31703.1 - 2.4e-39 135.0 1.9 3.9e-39 134.3 1.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS31703.1 - 6.2e-11 42.0 6.7 1.2e-10 41.1 4.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tim17 PF02466.14 EPS31704.1 - 5.8e-28 97.4 5.8 7e-28 97.2 4.0 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF2428 PF10350.4 EPS31705.1 - 1.4e-77 260.1 0.0 3.7e-77 258.8 0.0 1.8 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 EPS31705.1 - 0.00015 21.5 7.0 1 9.5 0.1 6.2 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 EPS31705.1 - 0.0003 20.9 5.8 0.54 10.5 0.2 5.2 6 0 0 6 6 6 2 HEAT repeats HEAT_EZ PF13513.1 EPS31705.1 - 0.0011 19.3 6.4 2.6 8.6 0.0 5.6 4 0 0 4 4 4 2 HEAT-like repeat PX PF00787.19 EPS31707.1 - 8.3e-20 70.6 0.1 2e-18 66.2 0.0 2.7 2 1 0 2 2 2 1 PX domain Vps5 PF09325.5 EPS31707.1 - 1.1e-09 37.9 10.6 2.1e-05 23.8 1.3 2.2 2 0 0 2 2 2 2 Vps5 C terminal like Peptidase_C10 PF01640.12 EPS31707.1 - 0.035 13.8 0.0 0.083 12.6 0.0 1.6 2 0 0 2 2 2 0 Peptidase C10 family Noggin PF05806.7 EPS31707.1 - 0.099 11.9 0.0 0.37 10.0 0.0 1.9 2 0 0 2 2 2 0 Noggin Glyco_hydro_43 PF04616.9 EPS31708.1 - 9.4e-34 116.7 0.4 1.4e-33 116.2 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 UCH PF00443.24 EPS31709.1 - 7.4e-69 231.8 0.0 1.5e-68 230.8 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPS31709.1 - 1.2e-15 57.7 0.0 1.7e-09 37.5 0.0 2.9 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EPS31709.1 - 2.7e-12 46.9 0.0 8e-12 45.4 0.0 1.9 1 0 0 1 1 1 1 DUSP domain DUF3785 PF12653.2 EPS31709.1 - 0.31 10.9 0.1 1.3 8.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3785) Zn_clus PF00172.13 EPS31710.1 - 0.33 10.8 27.4 0.8 9.6 0.1 4.6 3 1 1 4 4 4 0 Fungal Zn(2)-Cys(6) binuclear cluster domain APG17 PF04108.7 EPS31711.1 - 1.1e-134 449.3 2.5 1.3e-134 449.1 1.8 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 CAMP_factor PF07373.6 EPS31711.1 - 0.022 14.2 1.7 0.26 10.7 0.1 2.7 3 0 0 3 3 3 0 CAMP factor (Cfa) CALCOCO1 PF07888.6 EPS31711.1 - 0.14 10.4 7.5 0.064 11.5 0.2 2.1 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like AATF-Che1 PF13339.1 EPS31711.1 - 0.35 11.0 5.8 0.28 11.3 1.1 2.6 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor FliD_N PF02465.13 EPS31711.1 - 0.39 11.1 4.5 9.2 6.6 0.5 3.4 4 0 0 4 4 4 0 Flagellar hook-associated protein 2 N-terminus zf-C4H2 PF10146.4 EPS31711.1 - 2 8.3 5.8 17 5.3 0.3 3.1 2 1 0 3 3 3 0 Zinc finger-containing protein ALIX_LYPXL_bnd PF13949.1 EPS31711.1 - 2.4 7.0 12.1 0.06 12.3 1.3 2.8 2 2 1 3 3 3 0 ALIX V-shaped domain binding to HIV Syntaxin-6_N PF09177.6 EPS31711.1 - 5.6 7.4 11.3 13 6.3 0.5 4.2 2 2 2 4 4 4 0 Syntaxin 6, N-terminal Syntaxin PF00804.20 EPS31711.1 - 9.7 6.4 9.5 4.7 7.4 0.5 3.6 3 1 1 4 4 4 0 Syntaxin RIO1 PF01163.17 EPS31712.1 - 1.1e-73 246.6 0.0 1.1e-73 246.6 0.0 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 EPS31712.1 - 6.8e-05 22.7 0.0 0.0016 18.1 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EPS31712.1 - 0.001 18.1 0.1 0.44 9.5 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EPS31712.1 - 0.036 13.6 0.2 0.13 11.7 0.0 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase SMC_N PF02463.14 EPS31713.1 - 1.2e-70 237.2 5.7 2e-70 236.4 3.9 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EPS31713.1 - 5.2e-33 113.5 0.0 2.9e-32 111.1 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 EPS31713.1 - 1.1e-18 68.2 4.7 1.1e-18 68.2 3.3 6.9 2 2 2 4 4 1 1 AAA domain AAA_21 PF13304.1 EPS31713.1 - 1.5e-17 64.4 3.5 4.1e-09 36.8 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.1 EPS31713.1 - 4.2e-11 42.5 19.2 9.5e-09 34.7 0.1 3.9 2 2 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 EPS31713.1 - 0.00034 20.0 0.0 0.00076 18.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain APG6 PF04111.7 EPS31713.1 - 0.0014 17.7 10.7 0.0014 17.7 7.4 7.4 2 2 6 8 8 8 2 Autophagy protein Apg6 Reo_sigmaC PF04582.7 EPS31713.1 - 0.014 14.6 27.7 0.47 9.5 1.0 5.3 3 1 1 5 5 5 0 Reovirus sigma C capsid protein FliD_N PF02465.13 EPS31713.1 - 0.016 15.5 1.9 0.016 15.5 1.3 7.9 4 3 3 8 8 8 0 Flagellar hook-associated protein 2 N-terminus AAA_13 PF13166.1 EPS31713.1 - 0.026 13.0 88.6 0.3 9.4 0.0 6.1 3 2 2 6 6 6 0 AAA domain MCPsignal PF00015.16 EPS31713.1 - 0.61 9.5 44.2 0.11 12.0 2.7 6.2 6 0 0 6 6 6 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3605 PF12239.3 EPS31714.1 - 2.8e-55 186.5 0.0 1.7e-35 122.1 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3605) FAD_binding_6 PF00970.19 EPS31715.1 - 2e-30 104.8 0.0 3e-30 104.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EPS31715.1 - 2.2e-27 95.7 0.0 1.6e-26 93.0 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EPS31715.1 - 2.7e-06 27.3 0.0 0.00055 19.8 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EPS31715.1 - 0.00095 19.1 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain DUF4176 PF13780.1 EPS31715.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4176) MFS_1 PF07690.11 EPS31717.1 - 6.3e-17 61.3 56.2 3.6e-16 58.8 33.6 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPS31717.1 - 1.7e-12 46.3 16.8 1.7e-12 46.3 11.7 1.6 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PIP5K PF01504.13 EPS31721.1 - 6.7e-30 104.0 0.0 9.2e-30 103.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase tRNA-synt_1d PF00750.14 EPS31722.1 - 6.7e-83 278.4 6.8 5.1e-80 268.9 4.7 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EPS31722.1 - 4.7e-27 94.3 0.2 4.7e-27 94.3 0.1 1.8 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 EPS31722.1 - 1.7e-08 34.8 0.3 7e-08 32.9 0.0 2.2 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain ABC2_membrane PF01061.19 EPS31723.1 - 1.5e-28 99.4 29.1 2.3e-28 98.8 20.2 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EPS31723.1 - 3.7e-26 92.0 0.0 6.8e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EPS31723.1 - 1.3e-06 28.6 0.1 0.0068 16.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EPS31723.1 - 1e-05 25.6 0.0 1.8e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EPS31723.1 - 2.7e-05 23.3 0.1 5e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EPS31723.1 - 0.00033 20.1 0.4 0.0047 16.3 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 EPS31723.1 - 0.00074 19.6 0.1 0.003 17.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 EPS31723.1 - 0.00083 18.5 0.0 0.053 12.5 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EPS31723.1 - 0.00088 20.0 0.0 0.002 18.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EPS31723.1 - 0.0018 18.2 0.1 0.0037 17.2 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EPS31723.1 - 0.002 17.6 0.0 0.031 13.7 0.0 2.1 2 0 0 2 2 2 1 AAA-like domain SMC_N PF02463.14 EPS31723.1 - 0.0023 17.1 0.1 0.019 14.2 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_33 PF13671.1 EPS31723.1 - 0.0025 17.7 0.0 0.0051 16.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 EPS31723.1 - 0.003 16.3 0.1 0.005 15.6 0.1 1.3 1 0 0 1 1 1 1 ArgK protein Rad17 PF03215.10 EPS31723.1 - 0.0035 16.1 0.0 0.0052 15.5 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA PF00004.24 EPS31723.1 - 0.0058 16.8 0.1 0.041 14.0 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EPS31723.1 - 0.01 15.5 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase UPF0079 PF02367.12 EPS31723.1 - 0.01 15.4 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 EPS31723.1 - 0.013 15.8 0.0 0.028 14.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EPS31723.1 - 0.018 14.4 0.0 0.037 13.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.7 EPS31723.1 - 0.024 14.3 0.0 0.054 13.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.1 EPS31723.1 - 0.025 14.1 0.0 0.052 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 EPS31723.1 - 0.027 14.3 0.0 0.063 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EPS31723.1 - 0.027 13.3 0.0 0.043 12.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.1 EPS31723.1 - 0.032 13.8 0.1 0.065 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EPS31723.1 - 0.038 13.7 0.3 0.089 12.5 0.2 1.6 1 0 0 1 1 1 0 Part of AAA domain MobB PF03205.9 EPS31723.1 - 0.042 13.5 0.0 0.076 12.7 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 EPS31723.1 - 0.043 13.2 0.2 0.096 12.1 0.0 1.6 2 0 0 2 2 1 0 SRP54-type protein, GTPase domain PduV-EutP PF10662.4 EPS31723.1 - 0.051 13.0 0.0 0.096 12.1 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 EPS31723.1 - 0.054 12.9 0.1 0.096 12.1 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 EPS31723.1 - 0.057 13.3 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase RNA_helicase PF00910.17 EPS31723.1 - 0.079 13.1 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase SbcCD_C PF13558.1 EPS31723.1 - 0.087 12.7 0.0 0.27 11.1 0.0 1.9 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.9 EPS31723.1 - 0.098 12.3 0.0 0.24 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC2_membrane_3 PF12698.2 EPS31723.1 - 2.2 7.2 29.1 0.39 9.6 17.4 1.8 2 1 0 2 2 2 0 ABC-2 family transporter protein Epimerase PF01370.16 EPS31726.1 - 2.7e-21 76.0 0.0 3.9e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPS31726.1 - 3.6e-14 52.1 0.0 9.7e-14 50.7 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EPS31726.1 - 2.7e-12 46.1 0.0 5.7e-08 31.9 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 EPS31726.1 - 7e-12 45.7 0.0 1.4e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EPS31726.1 - 3.3e-06 26.5 0.0 9.6e-06 25.0 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 EPS31726.1 - 0.00024 21.0 0.0 0.00062 19.7 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EPS31726.1 - 0.00025 20.0 0.0 0.00053 18.9 0.0 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 EPS31726.1 - 0.023 14.3 0.4 4 7.0 0.0 2.3 2 0 0 2 2 2 0 KR domain RmlD_sub_bind PF04321.12 EPS31726.1 - 0.044 12.6 0.1 0.75 8.6 0.0 2.3 1 1 2 3 3 3 0 RmlD substrate binding domain AgrD PF05931.6 EPS31727.1 - 1.7 8.3 5.3 17 5.0 0.6 2.8 2 1 0 2 2 2 0 Staphylococcal AgrD protein Acetyltransf_2 PF00797.12 EPS31730.1 - 3.9e-34 118.2 0.0 5e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase MOZ_SAS PF01853.13 EPS31732.1 - 4.9e-78 260.7 0.0 6.9e-78 260.2 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family PHD PF00628.24 EPS31732.1 - 0.0047 16.6 11.2 0.0047 16.6 7.8 2.1 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 EPS31732.1 - 3.1 7.2 6.0 7.4 5.9 4.1 1.7 1 0 0 1 1 1 0 PHD-finger DEADboxA PF12343.3 EPS31733.1 - 0.11 12.7 8.0 0.47 10.7 1.3 2.4 1 1 1 2 2 2 0 Cold shock protein DEAD box A Velvet PF11754.3 EPS31735.1 - 7.9e-53 179.0 5.2 4e-37 127.7 0.3 2.3 1 1 1 2 2 2 2 Velvet factor AAA_17 PF13207.1 EPS31737.1 - 8e-05 23.4 0.0 0.0002 22.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPS31737.1 - 0.00089 19.5 0.0 0.0016 18.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 EPS31737.1 - 0.0017 17.9 0.3 0.0028 17.2 0.2 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family ABC_tran PF00005.22 EPS31737.1 - 0.0061 16.8 0.1 0.065 13.5 0.1 2.2 2 0 0 2 2 2 1 ABC transporter MobB PF03205.9 EPS31737.1 - 0.011 15.4 0.1 0.024 14.3 0.0 1.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_21 PF13304.1 EPS31737.1 - 0.026 14.5 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EPS31737.1 - 0.039 13.9 0.1 0.076 12.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain CPT PF07931.7 EPS31737.1 - 0.045 13.3 0.3 0.078 12.6 0.2 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_16 PF13191.1 EPS31737.1 - 0.1 12.5 0.3 0.23 11.4 0.1 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_33 PF13671.1 EPS31737.1 - 0.14 12.0 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EPS31737.1 - 0.14 11.2 0.1 0.21 10.6 0.1 1.2 1 0 0 1 1 1 0 Zeta toxin Rad17 PF03215.10 EPS31737.1 - 0.2 10.2 0.0 0.28 9.8 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein zf-met PF12874.2 EPS31738.1 - 1.2e-10 41.2 12.9 0.0009 19.3 0.1 4.7 4 0 0 4 4 4 4 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EPS31738.1 - 0.00023 21.2 20.9 0.031 14.4 0.1 5.1 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EPS31738.1 - 0.0054 16.9 33.6 0.74 10.2 2.1 6.3 6 1 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EPS31738.1 - 0.0098 15.9 21.3 0.96 9.5 0.0 5.0 2 2 3 5 5 5 3 C2H2 type zinc-finger (2 copies) zf-DNA_Pol PF08996.5 EPS31738.1 - 0.13 11.6 7.9 0.29 10.4 0.1 2.7 3 0 0 3 3 3 0 DNA Polymerase alpha zinc finger zf-DBF PF07535.7 EPS31738.1 - 0.57 9.9 12.2 9 6.0 4.9 3.9 3 1 0 3 3 3 0 DBF zinc finger zf-C2H2 PF00096.21 EPS31739.1 - 3.9e-08 33.1 26.9 0.16 12.3 0.1 4.8 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-Di19 PF05605.7 EPS31739.1 - 0.00046 20.2 0.2 0.00046 20.2 0.1 3.6 4 0 0 4 4 4 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 EPS31739.1 - 0.00074 19.6 22.3 0.38 11.1 0.6 4.8 5 0 0 5 5 4 2 C2H2-type zinc finger zf-met PF12874.2 EPS31739.1 - 0.0017 18.5 8.7 0.92 9.8 0.0 3.6 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 EPS31739.1 - 0.0022 17.6 0.1 0.0022 17.6 0.1 3.4 4 0 0 4 4 3 1 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.2 EPS31739.1 - 0.0036 17.3 11.6 0.8 9.8 1.0 4.1 3 1 1 4 4 4 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EPS31739.1 - 0.0048 17.0 15.6 0.086 13.0 1.5 3.9 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding DUF4187 PF13821.1 EPS31739.1 - 0.14 11.7 5.0 0.22 11.1 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4187) zf-C2H2_6 PF13912.1 EPS31739.1 - 0.16 11.8 22.0 1.5 8.8 0.8 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger DZR PF12773.2 EPS31739.1 - 0.36 10.6 5.0 1.4 8.7 0.6 2.7 2 1 0 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.1 EPS31739.1 - 0.93 8.7 5.0 3.5 6.9 3.5 2.0 1 1 0 1 1 1 0 zinc-ribbon domain zf-RING_3 PF14369.1 EPS31739.1 - 1.3 9.1 0.0 1.3 9.1 0.0 3.6 4 0 0 4 4 4 0 zinc-finger zinc_ribbon_2 PF13240.1 EPS31739.1 - 2 8.0 6.3 0.8 9.2 1.1 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zf-H2C2_2 PF13465.1 EPS31739.1 - 2.5 8.5 19.2 10 6.6 0.1 4.6 4 0 0 4 4 4 0 Zinc-finger double domain C1_4 PF07975.7 EPS31739.1 - 2.9 7.9 11.0 1.7 8.7 1.2 3.1 2 2 0 2 2 2 0 TFIIH C1-like domain SNF2_N PF00176.18 EPS31740.1 - 6.7e-33 113.7 0.0 2.2e-30 105.4 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EPS31740.1 - 0.00033 20.4 0.0 0.00081 19.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HMG_box PF00505.14 EPS31741.1 - 9.9e-22 76.9 0.9 1.7e-21 76.2 0.6 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EPS31741.1 - 5.9e-08 32.9 0.4 1.2e-07 31.9 0.3 1.5 1 0 0 1 1 1 1 HMG-box domain CD24 PF14984.1 EPS31742.1 - 1 9.1 5.0 2.3 8.0 0.8 2.3 2 0 0 2 2 2 0 CD24 protein Lipase_GDSL PF00657.17 EPS31744.1 - 0.001 18.9 0.0 0.0019 18.1 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Ribosomal_S6e PF01092.14 EPS31746.1 - 5.6e-58 194.1 0.1 1.1e-57 193.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e Pribosyltran_N PF13793.1 EPS31747.1 - 2.9e-46 155.9 1.4 1.7e-44 150.2 0.0 2.4 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EPS31747.1 - 3.4e-42 144.2 1.9 1.7e-35 122.4 0.6 2.5 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EPS31747.1 - 1.1e-13 51.0 0.6 1.3e-12 47.4 0.4 2.3 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EPS31747.1 - 3.3e-05 23.1 0.2 6.2e-05 22.2 0.2 1.5 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Chlorosome_CsmC PF11098.3 EPS31747.1 - 0.13 11.9 1.2 0.25 11.0 0.8 1.4 1 0 0 1 1 1 0 Chlorosome envelope protein C DUF913 PF06025.7 EPS31748.1 - 1.1e-150 501.5 0.0 1.1e-150 501.5 0.0 4.4 8 0 0 8 8 8 1 Domain of Unknown Function (DUF913) HECT PF00632.20 EPS31748.1 - 1.1e-96 323.6 0.0 1.9e-96 322.9 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 EPS31748.1 - 3e-91 306.1 3.4 3e-91 306.1 2.4 2.7 3 0 0 3 3 3 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 EPS31748.1 - 2.6e-32 110.9 10.1 2.6e-32 110.9 7.0 3.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4414) An_peroxidase PF03098.10 EPS31749.1 - 1.3e-100 337.3 0.0 2e-80 270.7 0.0 2.2 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.17 EPS31749.1 - 7.3e-11 41.2 0.4 8e-10 37.8 0.0 2.4 3 0 0 3 3 3 1 Cytochrome P450 Vps55 PF04133.9 EPS31749.1 - 0.14 11.8 0.0 0.65 9.7 0.0 2.0 2 0 0 2 2 2 0 Vacuolar protein sorting 55 Steroid_dh PF02544.11 EPS31752.1 - 7.7e-32 110.1 1.6 1e-31 109.7 1.1 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EPS31752.1 - 1.9e-05 24.0 2.3 2.8e-05 23.5 1.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 EPS31752.1 - 0.00046 20.2 0.3 0.0011 19.0 0.2 1.7 1 0 0 1 1 1 1 Phospholipid methyltransferase Glyco_transf_34 PF05637.7 EPS31753.1 - 2.9e-57 193.9 0.0 3.6e-57 193.6 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF3357 PF11837.3 EPS31753.1 - 0.12 12.2 0.4 0.21 11.4 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Ribosomal_L28 PF00830.14 EPS31754.1 - 4.5e-19 68.0 0.5 6.9e-19 67.4 0.4 1.3 1 0 0 1 1 1 1 Ribosomal L28 family HABP4_PAI-RBP1 PF04774.10 EPS31754.1 - 6 7.4 7.2 0.17 12.4 0.6 1.6 2 0 0 2 2 2 0 Hyaluronan / mRNA binding family TIP49 PF06068.8 EPS31755.1 - 1.6e-187 623.1 0.1 1.8e-187 622.9 0.1 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EPS31755.1 - 3.7e-11 43.3 0.2 3.9e-07 30.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EPS31755.1 - 2.7e-10 39.6 1.1 1.1e-06 27.9 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EPS31755.1 - 3.8e-06 27.0 0.0 0.0087 16.0 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EPS31755.1 - 1.2e-05 25.4 0.1 0.14 12.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EPS31755.1 - 5.2e-05 22.9 0.1 0.00015 21.4 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 EPS31755.1 - 0.00032 20.7 0.1 0.00068 19.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EPS31755.1 - 0.00064 19.4 0.2 0.16 11.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EPS31755.1 - 0.0012 18.0 0.3 0.003 16.6 0.2 1.6 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 EPS31755.1 - 0.0012 18.3 0.1 0.97 8.8 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.1 EPS31755.1 - 0.0021 17.4 0.0 0.0048 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EPS31755.1 - 0.011 14.8 0.1 0.49 9.5 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EPS31755.1 - 0.025 13.9 0.1 0.048 13.0 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 EPS31755.1 - 0.028 14.7 0.1 0.23 11.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 EPS31755.1 - 0.028 13.4 0.1 0.051 12.5 0.0 1.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) KaiC PF06745.8 EPS31755.1 - 0.029 13.4 0.2 0.11 11.6 0.0 1.9 2 0 0 2 2 2 0 KaiC AAA_17 PF13207.1 EPS31755.1 - 0.051 14.3 0.1 0.16 12.8 0.0 2.0 2 2 0 2 2 2 0 AAA domain DnaB_C PF03796.10 EPS31755.1 - 0.098 11.5 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain V-SNARE PF05008.10 EPS31756.1 - 6.9e-22 77.4 7.9 6.9e-22 77.4 5.5 1.7 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 EPS31756.1 - 1.3e-13 50.7 2.1 1.3e-13 50.7 1.4 2.8 3 1 0 3 3 2 1 Snare region anchored in the vesicle membrane C-terminus Phe_tRNA-synt_N PF02912.13 EPS31756.1 - 0.029 14.0 1.3 3.5 7.4 0.4 2.7 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain Fusion_gly PF00523.13 EPS31756.1 - 0.038 12.0 3.7 0.36 8.8 0.3 2.1 2 0 0 2 2 2 0 Fusion glycoprotein F0 YkyA PF10368.4 EPS31756.1 - 0.13 11.6 3.2 0.17 11.1 2.2 1.3 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein PRP1_N PF06424.7 EPS31756.1 - 0.29 11.4 4.7 0.62 10.3 3.2 1.6 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal ZapA PF05164.8 EPS31756.1 - 0.31 11.0 9.3 2.6 8.0 0.0 3.9 2 1 0 2 2 2 0 Cell division protein ZapA End3 PF12761.2 EPS31756.1 - 0.4 10.2 8.7 0.06 12.9 3.3 1.6 2 1 1 3 3 3 0 Actin cytoskeleton-regulatory complex protein END3 DivIVA PF05103.8 EPS31756.1 - 0.65 10.0 7.9 0.77 9.8 3.2 2.1 2 0 0 2 2 2 0 DivIVA protein Mnd1 PF03962.10 EPS31756.1 - 0.89 9.1 10.6 0.27 10.8 0.3 2.1 1 1 1 2 2 2 0 Mnd1 family TBCA PF02970.11 EPS31756.1 - 1.2 9.2 8.5 0.24 11.5 2.2 2.4 2 1 0 2 2 2 0 Tubulin binding cofactor A Exonuc_VII_L PF02601.10 EPS31756.1 - 2.5 7.1 8.8 5.9 5.9 6.1 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit Histone_HNS PF00816.16 EPS31756.1 - 3.5 8.1 5.3 0.83 10.2 1.2 1.8 2 0 0 2 2 2 0 H-NS histone family DUF349 PF03993.7 EPS31756.1 - 6 7.0 7.5 12 6.1 1.7 2.7 2 1 0 2 2 2 0 Domain of Unknown Function (DUF349) DUF2407_C PF13373.1 EPS31757.1 - 3.8e-41 140.2 0.1 6.6e-41 139.4 0.1 1.4 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 EPS31757.1 - 2.5e-29 101.3 0.1 6.3e-29 100.0 0.1 1.7 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 EPS31757.1 - 0.002 17.4 0.0 0.0041 16.4 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family C1_3 PF07649.7 EPS31758.1 - 0.075 13.0 1.2 2.8 8.0 0.0 2.8 3 0 0 3 3 3 0 C1-like domain zf-GRF PF06839.7 EPS31758.1 - 7 6.6 7.0 12 5.8 1.8 2.6 2 1 0 2 2 2 0 GRF zinc finger Fe-S_biosyn PF01521.15 EPS31759.1 - 2.2e-17 62.9 0.0 3e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF1741 PF08427.5 EPS31760.1 - 2e-91 305.6 0.0 1.6e-90 302.7 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) UPF0118 PF01594.11 EPS31760.1 - 0.24 10.3 1.0 0.37 9.7 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF20 MRG PF05712.8 EPS31761.1 - 7.6e-51 171.7 0.1 1.2e-50 171.0 0.1 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 EPS31761.1 - 2e-09 36.9 2.6 4.1e-09 36.0 1.8 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 EPS31761.1 - 0.00085 18.9 2.2 0.0021 17.7 1.5 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Cnl2_NKP2 PF09447.5 EPS31762.1 - 3.3e-28 97.1 0.6 7.2e-28 96.0 0.4 1.6 1 0 0 1 1 1 1 Cnl2/NKP2 family protein GlutR_dimer PF00745.15 EPS31762.1 - 0.0079 16.1 2.2 0.014 15.3 0.7 1.9 2 0 0 2 2 2 1 Glutamyl-tRNAGlu reductase, dimerisation domain DUF1887 PF09002.6 EPS31762.1 - 0.016 13.6 0.9 0.018 13.4 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1887) DUF948 PF06103.6 EPS31762.1 - 0.019 14.8 0.0 0.047 13.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Nsp1_C PF05064.8 EPS31762.1 - 0.075 12.6 2.6 0.93 9.1 0.5 2.3 1 1 1 2 2 2 0 Nsp1-like C-terminal region DUF572 PF04502.8 EPS31762.1 - 0.3 10.2 4.2 0.36 10.0 2.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) FTCD_C PF04961.7 EPS31762.1 - 0.36 10.2 2.7 1.1 8.6 1.9 1.8 1 1 0 1 1 1 0 Formiminotransferase-cyclodeaminase APG6 PF04111.7 EPS31762.1 - 0.75 8.7 3.9 1.3 8.0 2.1 1.7 1 1 1 2 2 2 0 Autophagy protein Apg6 Toxin_39 PF15500.1 EPS31762.1 - 0.78 9.9 3.2 1 9.5 0.4 2.2 1 1 1 2 2 2 0 Putative RNase-like toxin Ctf8 PF09696.5 EPS31763.1 - 2.1e-39 134.0 0.0 2.6e-39 133.7 0.0 1.1 1 0 0 1 1 1 1 Ctf8 Dabb PF07876.7 EPS31764.1 - 2.6e-12 47.0 0.0 2.8e-12 46.9 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF1687 PF07955.6 EPS31764.1 - 0.083 12.8 0.1 0.29 11.0 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1687) PocR PF10114.4 EPS31764.1 - 0.14 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Sensory domain found in PocR RabGAP-TBC PF00566.13 EPS31765.1 - 5e-52 176.4 0.3 1.9e-51 174.6 0.2 2.0 1 1 0 1 1 1 1 Rab-GTPase-TBC domain PPTA PF01239.17 EPS31766.1 - 5.8e-33 110.8 13.3 4.7e-07 28.8 0.1 5.6 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat WD40 PF00400.27 EPS31767.1 - 1.3e-15 56.5 1.1 0.00015 21.4 0.0 5.8 5 0 0 5 5 5 3 WD domain, G-beta repeat Utp12 PF04003.7 EPS31768.1 - 1.1e-22 79.9 0.1 1.8e-22 79.2 0.1 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family CENP-T PF15511.1 EPS31768.1 - 1 8.5 37.5 0.47 9.6 3.1 2.4 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T RuBisCO_large PF00016.15 EPS31769.1 - 0.022 13.5 0.0 0.027 13.3 0.0 1.0 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain Bromodomain PF00439.20 EPS31770.1 - 1.4e-39 133.8 0.6 7.8e-20 70.5 0.0 2.8 3 0 0 3 3 3 2 Bromodomain DUF3573 PF12097.3 EPS31770.1 - 1.5 7.3 3.8 3.2 6.2 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) HAUS4 PF14735.1 EPS31772.1 - 0.01 15.1 2.7 0.033 13.4 0.8 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 4 DUF904 PF06005.7 EPS31772.1 - 0.067 13.4 5.0 1.9 8.8 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF904) ORC5_C PF14630.1 EPS31772.1 - 0.54 9.6 3.3 0.38 10.1 0.6 1.8 2 0 0 2 2 2 0 Origin recognition complex (ORC) subunit 5 C-terminus PARG_cat PF05028.9 EPS31773.1 - 6.4e-28 97.9 0.0 3.1e-17 62.8 0.0 2.2 1 1 1 2 2 2 2 Poly (ADP-ribose) glycohydrolase (PARG) AKAP_110 PF05716.8 EPS31773.1 - 0.005 14.8 0.0 0.0071 14.4 0.0 1.1 1 0 0 1 1 1 1 A-kinase anchor protein 110 kDa (AKAP 110) zf-CSL PF05207.8 EPS31774.1 - 6.5e-24 83.2 0.7 7.9e-24 82.9 0.5 1.1 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.5 EPS31774.1 - 0.022 14.6 0.2 0.041 13.8 0.1 1.4 1 0 0 1 1 1 0 Zinc ribbon domain NAD_binding_8 PF13450.1 EPS31776.1 - 1.4e-12 47.4 0.0 2.9e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EPS31776.1 - 4.1e-09 36.0 0.0 6.4e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPS31776.1 - 1.5e-07 30.6 0.4 3.9e-07 29.2 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EPS31776.1 - 1e-06 27.9 0.0 1.8e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EPS31776.1 - 1.3e-06 27.2 0.3 3.6e-06 25.7 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 EPS31776.1 - 1.1e-05 25.4 0.1 9e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EPS31776.1 - 1.9e-05 23.9 0.0 3.2e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EPS31776.1 - 3.7e-05 23.8 0.2 0.014 15.4 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPS31776.1 - 0.00025 21.3 0.0 0.00048 20.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EPS31776.1 - 0.00038 19.6 0.2 0.00072 18.6 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EPS31776.1 - 0.0018 17.4 0.1 0.0031 16.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 EPS31776.1 - 0.0035 16.2 0.0 0.0058 15.5 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 EPS31776.1 - 0.0041 15.8 0.1 0.0057 15.3 0.1 1.1 1 0 0 1 1 1 1 Tryptophan halogenase IlvN PF07991.7 EPS31776.1 - 0.026 13.8 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Lycopene_cycl PF05834.7 EPS31776.1 - 0.035 13.0 0.0 0.059 12.2 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.11 EPS31776.1 - 0.039 13.3 0.0 0.08 12.3 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 EPS31776.1 - 0.066 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_9 PF13454.1 EPS31776.1 - 0.09 12.5 0.1 0.26 11.0 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Frataxin_Cyay PF01491.11 EPS31778.1 - 5.5e-32 109.8 0.0 6.9e-32 109.4 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain FixH PF05751.6 EPS31778.1 - 0.049 13.4 0.0 0.059 13.1 0.0 1.2 1 0 0 1 1 1 0 FixH His_Phos_2 PF00328.17 EPS31779.1 - 1.9e-26 93.2 0.1 2.3e-26 92.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 EPS31779.1 - 0.00032 20.8 0.0 0.00044 20.3 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Lactamase_B PF00753.22 EPS31781.1 - 1.4e-09 37.8 0.9 6.7e-09 35.6 0.6 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EPS31781.1 - 1.1e-05 25.0 0.0 1.6e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EPS31781.1 - 0.022 14.4 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain MFS_1 PF07690.11 EPS31782.1 - 4e-25 88.2 68.7 7e-17 61.1 24.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ATP1G1_PLM_MAT8 PF02038.11 EPS31782.1 - 0.31 10.0 1.8 0.91 8.5 0.5 2.3 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family TPP_enzyme_N PF02776.13 EPS31783.1 - 3.6e-57 192.6 0.0 7.3e-57 191.5 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EPS31783.1 - 3.1e-42 143.7 0.1 9.2e-40 135.7 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EPS31783.1 - 3.2e-28 98.2 0.0 6.3e-28 97.2 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain AAL_decarboxy PF03306.8 EPS31784.1 - 4.3e-66 222.1 0.2 4.9e-66 221.9 0.1 1.0 1 0 0 1 1 1 1 Alpha-acetolactate decarboxylase Cellulase PF00150.13 EPS31785.1 - 4.5e-13 49.0 0.0 6.6e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF202 PF02656.10 EPS31786.1 - 9.9e-13 48.1 8.0 1.5e-12 47.4 3.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF4117 PF13491.1 EPS31786.1 - 0.035 13.5 2.2 0.038 13.4 1.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4117) DUF2207 PF09972.4 EPS31786.1 - 0.079 11.5 1.3 0.081 11.4 0.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2615 PF11027.3 EPS31786.1 - 0.33 10.8 1.7 0.54 10.2 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) CoA_binding_3 PF13727.1 EPS31786.1 - 0.96 9.2 4.5 1.4 8.6 3.1 1.3 1 1 0 1 1 1 0 CoA-binding domain DUF805 PF05656.9 EPS31786.1 - 4.2 7.2 6.8 1.7 8.4 2.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF805) GMC_oxred_N PF00732.14 EPS31787.1 - 1.6e-60 204.7 0.0 2.2e-60 204.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EPS31787.1 - 2.7e-32 112.0 0.7 6.2e-32 110.8 0.5 1.7 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EPS31787.1 - 0.00023 20.1 3.5 0.00096 18.1 0.4 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EPS31787.1 - 0.001 18.0 0.1 0.0017 17.3 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EPS31787.1 - 0.0024 17.9 0.2 3.5 7.6 0.2 3.4 2 2 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EPS31787.1 - 0.012 14.2 0.0 0.073 11.6 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase FAD_binding_2 PF00890.19 EPS31787.1 - 0.014 14.2 0.3 0.065 12.0 0.1 2.0 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.1 EPS31787.1 - 0.034 14.1 0.1 0.1 12.6 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EPS31787.1 - 0.16 11.0 2.1 0.75 8.8 0.0 2.8 3 1 0 3 3 3 0 Thi4 family MFS_1 PF07690.11 EPS31788.1 - 3.4e-17 62.2 38.0 3.4e-17 62.2 26.4 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EPS31788.1 - 4.1e-07 29.6 5.2 4.1e-07 29.6 3.6 2.5 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 zf-C2H2_4 PF13894.1 EPS31789.1 - 0.0035 17.5 30.0 0.12 12.7 4.6 5.0 4 0 0 4 4 4 4 C2H2-type zinc finger BIR PF00653.16 EPS31789.1 - 0.0035 17.7 2.7 2 8.8 0.4 2.8 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain Methyltransf_PK PF05891.7 EPS31790.1 - 2.9e-68 229.4 0.0 3.4e-68 229.2 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 EPS31790.1 - 8.9e-07 28.7 0.0 1.2e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPS31790.1 - 0.0014 19.1 0.0 0.0025 18.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS31790.1 - 0.0029 18.1 0.0 0.0051 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EPS31790.1 - 0.024 13.8 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase DUF711 PF05167.7 EPS31790.1 - 0.094 11.4 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised ACR (DUF711) Methyltransf_12 PF08242.7 EPS31790.1 - 0.15 12.5 0.0 0.37 11.3 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain GFA PF04828.9 EPS31791.1 - 5e-05 23.1 0.0 6.7e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Zn_ribbon_recom PF13408.1 EPS31791.1 - 0.082 13.1 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain FAD_binding_4 PF01565.18 EPS31792.1 - 3.9e-16 58.7 0.7 7.3e-16 57.9 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EPS31792.1 - 1.4e-07 31.3 0.1 3.8e-07 29.9 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EPS31792.1 - 0.083 12.0 0.1 0.14 11.3 0.1 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding DAO PF01266.19 EPS31793.1 - 4.6e-27 94.8 1.4 5.3e-27 94.6 1.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPS31793.1 - 0.00021 20.2 0.0 0.00028 19.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 EPS31793.1 - 0.00085 19.1 0.1 0.33 10.7 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox PF00070.22 EPS31793.1 - 0.0031 17.8 0.1 0.0089 16.4 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPS31793.1 - 0.0065 16.4 0.1 0.0065 16.4 0.0 2.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EPS31793.1 - 0.015 15.1 0.0 0.036 13.9 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPS31793.1 - 0.019 14.0 0.5 0.057 12.5 0.1 2.0 2 0 0 2 2 2 0 Thi4 family HTH_28 PF13518.1 EPS31793.1 - 0.034 14.1 0.0 0.094 12.7 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain ThiF PF00899.16 EPS31793.1 - 0.038 13.8 0.5 0.12 12.2 0.1 2.0 2 0 0 2 2 2 0 ThiF family NAD_binding_7 PF13241.1 EPS31793.1 - 0.06 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_binding_3 PF01494.14 EPS31793.1 - 0.062 12.3 0.2 0.13 11.3 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain ApbA PF02558.11 EPS31793.1 - 0.082 12.3 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Ldh_1_N PF00056.18 EPS31793.1 - 0.099 12.4 0.1 8.7 6.1 0.0 2.3 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 EPS31793.1 - 0.13 11.1 0.3 0.33 9.8 0.1 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein FA_desaturase PF00487.19 EPS31794.1 - 9.5e-29 100.6 25.8 1.4e-28 100.0 17.9 1.2 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EPS31794.1 - 0.079 12.9 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) NIF PF03031.13 EPS31795.1 - 2.4e-53 180.0 0.0 3.7e-53 179.4 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase IF-2B PF01008.12 EPS31796.1 - 6.4e-61 205.8 0.7 4.6e-37 127.5 0.0 2.7 2 1 0 2 2 2 2 Initiation factor 2 subunit family Ribosom_S12_S23 PF00164.20 EPS31797.1 - 4.4e-12 45.4 0.0 6.6e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Presenilin PF01080.12 EPS31798.1 - 0.89 8.3 2.5 1.4 7.6 1.7 1.3 1 0 0 1 1 1 0 Presenilin Mn_catalase PF05067.7 EPS31799.1 - 0.06 12.1 0.1 0.2 10.4 0.1 1.7 1 1 0 1 1 1 0 Manganese containing catalase DUF2723 PF11028.3 EPS31799.1 - 0.13 11.7 0.1 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2723) Ribosomal_L17 PF01196.14 EPS31800.1 - 1.3e-30 105.8 0.0 2.3e-30 105.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L17 Porin_O_P PF07396.6 EPS31800.1 - 0.048 12.5 0.0 0.064 12.1 0.0 1.1 1 0 0 1 1 1 0 Phosphate-selective porin O and P SUZ PF12752.2 EPS31801.1 - 1.7e-15 57.3 3.4 1.7e-15 57.3 2.4 3.8 3 0 0 3 3 3 1 SUZ domain R3H PF01424.17 EPS31801.1 - 4.2e-08 32.7 0.1 1.4e-07 31.0 0.0 1.9 2 0 0 2 2 2 1 R3H domain zf-CCHC_3 PF13917.1 EPS31802.1 - 7.7e-19 67.1 3.3 1.8e-18 65.9 2.3 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EPS31802.1 - 0.0041 16.9 1.3 0.0068 16.2 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 EPS31802.1 - 0.0052 16.2 3.1 0.013 14.9 0.4 2.4 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger cwf18 PF08315.7 EPS31803.1 - 4.1e-43 146.9 6.8 6e-43 146.3 4.7 1.2 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor HK97-gp10_like PF04883.7 EPS31803.1 - 4.6 8.2 5.7 7.3 7.6 0.3 2.5 3 0 0 3 3 3 0 Bacteriophage HK97-gp10, putative tail-component PPR_2 PF13041.1 EPS31804.1 - 2.5e-10 40.1 7.6 1.8e-05 24.6 0.1 5.8 5 2 2 7 7 7 3 PPR repeat family PPR_3 PF13812.1 EPS31804.1 - 9.7e-08 31.7 4.9 0.043 14.0 0.1 7.0 7 0 0 7 7 7 2 Pentatricopeptide repeat domain PPR PF01535.15 EPS31804.1 - 3e-05 23.6 0.0 0.098 12.6 0.0 4.2 3 0 0 3 3 3 2 PPR repeat PPR_1 PF12854.2 EPS31804.1 - 0.0056 16.1 0.0 0.067 12.6 0.0 2.9 3 0 0 3 3 3 1 PPR repeat DUF1242 PF06842.7 EPS31805.1 - 5e-19 67.5 0.2 7.1e-19 67.0 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) PAGK PF15284.1 EPS31805.1 - 0.038 13.7 0.1 0.051 13.3 0.0 1.3 1 0 0 1 1 1 0 Phage-encoded virulence factor TFIID-18kDa PF02269.11 EPS31806.1 - 2.3e-24 85.0 0.0 3.9e-24 84.2 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-S PF15630.1 EPS31806.1 - 3.6e-05 23.8 0.0 7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 EPS31806.1 - 4.8e-05 23.4 0.4 0.00011 22.1 0.0 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 EPS31806.1 - 0.002 18.0 0.0 0.0037 17.1 0.0 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.8 EPS31806.1 - 0.0031 17.1 0.0 0.0054 16.4 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 EPS31806.1 - 0.007 16.6 0.0 0.014 15.6 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 EPS31806.1 - 0.022 14.7 0.1 0.022 14.7 0.1 2.4 3 0 0 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Vfa1 PF08432.5 EPS31806.1 - 1.4 8.9 5.6 1.8 8.5 3.9 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RRP7 PF12923.2 EPS31806.1 - 1.8 8.6 10.1 1.3 9.0 5.9 1.5 1 1 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) zf-P11 PF03854.9 EPS31807.1 - 0.2 11.1 3.0 0.33 10.4 2.1 1.3 1 0 0 1 1 1 0 P-11 zinc finger zf-PHD-like PF15446.1 EPS31807.1 - 0.28 10.4 7.5 0.53 9.5 5.2 1.4 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain JAB PF01398.16 EPS31808.1 - 6.2e-17 61.3 0.0 1.1e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EPS31808.1 - 1.1e-16 60.9 0.1 1.9e-16 60.1 0.1 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function DUF1253 PF06862.7 EPS31809.1 - 3.5e-159 529.9 0.0 4.9e-159 529.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) Rotamase_2 PF13145.1 EPS31809.1 - 0.49 11.0 6.9 1 9.9 3.3 2.5 2 1 0 3 3 3 0 PPIC-type PPIASE domain Glyco_hydro_61 PF03443.9 EPS31810.1 - 6.3e-39 134.0 0.6 1.1e-38 133.2 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Herpes_capsid PF06112.6 EPS31810.1 - 0.036 14.1 3.7 0.064 13.3 2.6 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein EamA PF00892.15 EPS31811.1 - 4.7e-18 65.4 27.2 4.5e-12 46.1 5.5 3.8 3 1 1 4 4 4 3 EamA-like transporter family EmrE PF13536.1 EPS31811.1 - 3.6e-06 27.1 4.4 3.6e-06 27.1 3.1 3.8 2 2 1 3 3 3 2 Multidrug resistance efflux transporter DUF606 PF04657.8 EPS31811.1 - 0.16 12.0 23.1 0.1 12.6 4.7 3.1 3 0 0 3 3 3 0 Protein of unknown function, DUF606 SpoIIIAH PF12685.2 EPS31811.1 - 2.7 7.4 9.1 1.5 8.2 0.2 2.8 3 0 0 3 3 3 0 SpoIIIAH-like protein SOG2 PF10428.4 EPS31811.1 - 4.2 5.9 10.6 2 6.9 5.1 1.9 2 0 0 2 2 2 0 RAM signalling pathway protein DUF1680 PF07944.7 EPS31812.1 - 1.5e-139 465.6 0.2 1.7e-139 465.4 0.1 1.0 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) CTP_transf_2 PF01467.21 EPS31813.1 - 3.6e-22 79.1 0.0 5.7e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase FAD_binding_4 PF01565.18 EPS31814.1 - 1.6e-12 47.0 4.5 3.5e-12 45.9 2.6 2.0 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 EPS31814.1 - 2.1e-12 46.7 0.1 5.1e-12 45.4 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like Glyco_hydro_28 PF00295.12 EPS31814.1 - 0.017 14.0 1.5 0.026 13.4 1.1 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 28 TonB_dep_Rec PF00593.19 EPS31814.1 - 0.1 12.5 0.1 0.1 12.5 0.1 2.9 3 0 0 3 3 3 0 TonB dependent receptor PP2C PF00481.16 EPS31816.1 - 8.1e-82 274.4 0.1 1.7e-81 273.4 0.0 1.5 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.1 EPS31816.1 - 0.00054 19.4 0.0 0.0013 18.2 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C MOZART1 PF12554.3 EPS31818.1 - 4.3e-24 83.6 1.3 5.7e-24 83.3 0.9 1.2 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated SRP54_N PF02881.14 EPS31818.1 - 0.0097 15.9 0.4 0.02 14.9 0.3 1.6 1 1 0 1 1 1 1 SRP54-type protein, helical bundle domain WXG100 PF06013.7 EPS31818.1 - 0.015 15.2 0.1 1.3 9.1 0.0 2.1 2 0 0 2 2 2 0 Proteins of 100 residues with WXG RE_AlwI PF09491.5 EPS31818.1 - 0.059 11.8 0.0 0.065 11.6 0.0 1.0 1 0 0 1 1 1 0 AlwI restriction endonuclease DUF3926 PF13080.1 EPS31818.1 - 0.067 12.7 0.4 0.12 11.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3926) DUF1844 PF08899.6 EPS31818.1 - 0.094 12.6 0.1 0.16 11.8 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1844) CUE PF02845.11 EPS31819.1 - 2.5e-13 49.2 0.0 3.8e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 CUE domain UBA_4 PF14555.1 EPS31819.1 - 0.013 14.9 0.2 0.024 14.1 0.1 1.4 1 0 0 1 1 1 0 UBA-like domain OB_NTP_bind PF07717.11 EPS31820.1 - 3.3e-22 78.4 0.0 5.6e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EPS31820.1 - 1.5e-20 73.1 0.0 3e-20 72.1 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EPS31820.1 - 1.1e-12 47.6 0.0 2.1e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EPS31820.1 - 6.6e-06 26.3 0.0 1.9e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EPS31820.1 - 8.5e-05 22.1 0.3 0.00021 20.8 0.2 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 EPS31820.1 - 0.0092 14.9 0.1 0.023 13.6 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.1 EPS31820.1 - 0.01 15.4 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EPS31820.1 - 0.012 15.0 0.1 0.16 11.3 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 EPS31820.1 - 0.024 14.5 0.2 3.7 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EPS31820.1 - 0.094 12.2 0.0 0.37 10.3 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EPS31820.1 - 0.17 10.9 1.0 0.66 9.0 0.1 2.2 1 1 1 2 2 2 0 Zeta toxin PITH PF06201.8 EPS31821.1 - 3.7e-47 159.8 0.0 4.5e-47 159.6 0.0 1.1 1 0 0 1 1 1 1 PITH domain Snf7 PF03357.16 EPS31822.1 - 1.7e-35 121.8 6.9 2.3e-35 121.4 4.7 1.1 1 0 0 1 1 1 1 Snf7 DUF2203 PF09969.4 EPS31822.1 - 0.3 11.3 4.4 2 8.6 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) AAA PF00004.24 EPS31823.1 - 8.9e-89 294.4 0.0 9.5e-44 148.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EPS31823.1 - 6.4e-14 51.5 0.0 7.4e-07 28.4 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EPS31823.1 - 1.9e-13 50.8 1.6 2.6e-05 24.2 0.0 4.4 2 2 2 4 4 4 2 AAA ATPase domain AAA_22 PF13401.1 EPS31823.1 - 7.3e-13 48.7 0.2 0.0031 17.6 0.0 5.2 2 2 1 3 3 3 2 AAA domain AAA_5 PF07728.9 EPS31823.1 - 3.4e-11 43.0 0.2 0.00067 19.3 0.0 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EPS31823.1 - 1e-10 42.5 0.0 1e-05 26.3 0.0 3.1 2 2 0 2 2 2 2 AAA domain AAA_2 PF07724.9 EPS31823.1 - 1.1e-10 41.6 0.0 9e-05 22.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EPS31823.1 - 3.3e-10 39.9 0.0 0.00011 22.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EPS31823.1 - 1.8e-09 36.9 0.0 0.0012 17.9 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_14 PF13173.1 EPS31823.1 - 2.2e-09 37.3 0.0 0.00078 19.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 EPS31823.1 - 1e-08 34.3 0.0 0.0001 21.2 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus AAA_19 PF13245.1 EPS31823.1 - 2.5e-08 33.5 0.2 0.0088 15.7 0.0 3.5 3 0 0 3 3 3 2 Part of AAA domain RNA_helicase PF00910.17 EPS31823.1 - 1.1e-07 32.0 0.0 0.0056 16.8 0.0 2.6 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.1 EPS31823.1 - 2e-07 31.1 0.0 0.0042 17.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EPS31823.1 - 2.1e-07 30.5 0.5 0.019 14.4 0.0 2.6 2 1 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 EPS31823.1 - 2.8e-07 29.9 0.3 0.019 14.1 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EPS31823.1 - 7.9e-07 28.6 4.0 0.46 9.8 0.0 4.6 2 2 1 4 4 4 2 AAA domain AAA_18 PF13238.1 EPS31823.1 - 1.2e-06 28.8 0.0 0.011 15.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EPS31823.1 - 1.4e-06 28.0 0.4 0.12 11.9 0.0 4.0 3 1 0 4 4 4 2 NACHT domain AAA_3 PF07726.6 EPS31823.1 - 1.6e-06 27.7 0.0 0.0058 16.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 EPS31823.1 - 1.7e-05 24.0 0.0 0.44 9.6 0.0 3.2 2 1 0 3 3 3 2 KaiC Cytidylate_kin2 PF13189.1 EPS31823.1 - 4e-05 23.5 0.0 0.0055 16.6 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family PhoH PF02562.11 EPS31823.1 - 4.3e-05 22.8 0.0 0.11 11.7 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein Sigma54_activ_2 PF14532.1 EPS31823.1 - 4.6e-05 23.4 0.0 0.43 10.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 EPS31823.1 - 6.5e-05 23.2 0.0 0.41 10.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter Sigma54_activat PF00158.21 EPS31823.1 - 6.7e-05 22.4 0.0 0.21 11.0 0.0 2.9 3 0 0 3 3 3 2 Sigma-54 interaction domain SKI PF01202.17 EPS31823.1 - 0.00012 21.9 0.0 0.44 10.4 0.0 2.8 2 0 0 2 2 2 2 Shikimate kinase AFG1_ATPase PF03969.11 EPS31823.1 - 0.00031 19.6 0.0 0.15 10.8 0.0 2.9 2 1 0 2 2 2 1 AFG1-like ATPase Arch_ATPase PF01637.13 EPS31823.1 - 0.00034 20.4 0.0 2 8.0 0.0 3.5 2 2 1 3 3 3 1 Archaeal ATPase NB-ARC PF00931.17 EPS31823.1 - 0.00035 19.5 0.0 0.28 9.9 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain ResIII PF04851.10 EPS31823.1 - 0.00068 19.5 0.0 2.2 8.0 0.0 2.8 2 1 1 3 3 2 2 Type III restriction enzyme, res subunit Rad17 PF03215.10 EPS31823.1 - 0.00074 18.3 0.0 0.28 9.8 0.0 2.3 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Parvo_NS1 PF01057.12 EPS31823.1 - 0.001 18.0 0.0 1.3 7.8 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_11 PF13086.1 EPS31823.1 - 0.0026 17.3 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EPS31823.1 - 0.0028 17.2 0.0 0.88 9.2 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 DUF815 PF05673.8 EPS31823.1 - 0.0032 16.4 0.0 0.062 12.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Viral_helicase1 PF01443.13 EPS31823.1 - 0.0034 16.9 0.0 1.9 7.9 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 EPS31823.1 - 0.0092 15.7 0.1 2.1 8.0 0.0 3.0 2 1 0 3 3 3 1 NTPase ATP-synt_ab PF00006.20 EPS31823.1 - 0.01 15.3 0.0 2 7.8 0.0 2.5 3 0 0 3 3 2 0 ATP synthase alpha/beta family, nucleotide-binding domain CPT PF07931.7 EPS31823.1 - 0.013 15.1 0.0 0.32 10.6 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_24 PF13479.1 EPS31823.1 - 0.013 15.0 0.1 1.5 8.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain IPT PF01745.11 EPS31823.1 - 0.026 13.7 0.0 2.9 6.9 0.0 2.5 2 0 0 2 2 2 0 Isopentenyl transferase Med3 PF11593.3 EPS31823.1 - 0.043 13.0 0.2 0.063 12.5 0.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2075 PF09848.4 EPS31823.1 - 0.045 12.7 0.1 5.3 5.9 0.0 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF3538 PF12057.3 EPS31823.1 - 0.099 12.2 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3538) AAA_23 PF13476.1 EPS31823.1 - 0.13 12.6 0.0 3.3 8.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EPS31823.1 - 0.13 11.8 0.1 16 5.0 0.0 2.6 3 0 0 3 3 2 0 AAA domain MSA-2c PF12238.3 EPS31823.1 - 0.44 10.1 2.6 14 5.3 0.0 2.3 2 0 0 2 2 2 0 Merozoite surface antigen 2c Glyco_hydro_76 PF03663.9 EPS31824.1 - 9.8e-131 436.5 14.5 1.3e-130 436.1 10.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 BOP1NT PF08145.7 EPS31825.1 - 1.1e-106 356.3 6.2 1.6e-106 355.8 4.3 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 EPS31825.1 - 5.9e-26 89.3 11.1 1.4e-10 40.6 0.2 6.3 6 1 0 6 6 6 4 WD domain, G-beta repeat Zn_clus PF00172.13 EPS31826.1 - 5.5e-08 32.5 7.0 1.6e-07 31.1 4.8 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_L37ae PF01780.14 EPS31826.1 - 0.013 15.4 0.8 1.2 9.0 0.2 2.3 2 0 0 2 2 2 0 Ribosomal L37ae protein family Rep_fac-A_C PF08646.5 EPS31826.1 - 2.5 7.8 6.8 13 5.4 0.0 2.2 2 0 0 2 2 2 0 Replication factor-A C terminal domain Leo1 PF04004.8 EPS31827.1 - 7.2e-30 103.9 0.0 1.3e-29 103.0 0.0 1.5 1 0 0 1 1 1 1 Leo1-like protein CENP-T PF15511.1 EPS31827.1 - 0.88 8.7 32.3 1.2 8.2 3.7 2.2 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T Mob1_phocein PF03637.12 EPS31828.1 - 6.4e-31 107.3 2.4 1.6e-14 53.9 0.8 2.2 2 0 0 2 2 2 2 Mob1/phocein family UCR_14kD PF02271.11 EPS31829.1 - 0.027 14.2 0.0 0.037 13.7 0.0 1.1 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex 14kD subunit GCD14_N PF14801.1 EPS31829.1 - 0.094 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit N-term B2 PF11473.3 EPS31830.1 - 0.075 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA binding protein B2 PhoD PF09423.5 EPS31831.1 - 2.8e-12 45.9 0.2 2.3e-07 29.7 0.2 2.4 2 1 0 2 2 2 2 PhoD-like phosphatase AA_permease_2 PF13520.1 EPS31832.1 - 2.1e-37 128.6 53.7 2.8e-37 128.3 37.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPS31832.1 - 6.6e-25 87.3 49.6 8.7e-25 86.9 34.4 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3336 PF11815.3 EPS31833.1 - 2.9e-39 133.8 0.7 1e-38 132.1 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EPS31833.1 - 1.4e-13 51.2 1.8 2.1e-13 50.6 0.1 2.1 3 0 0 3 3 3 1 Patatin-like phospholipase TAFH PF07531.9 EPS31833.1 - 0.045 13.4 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 NHR1 homology to TAF Sm_multidrug_ex PF06695.6 EPS31833.1 - 0.078 13.1 0.2 0.5 10.5 0.1 2.3 2 0 0 2 2 2 0 Putative small multi-drug export protein Ribosomal_L6 PF00347.18 EPS31834.1 - 5.2e-23 81.3 4.3 4.5e-11 43.0 1.3 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Glutaredoxin PF00462.19 EPS31835.1 - 4e-13 49.1 0.0 7.5e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin Abhydrolase_6 PF12697.2 EPS31836.1 - 2.8e-19 69.9 1.8 2.5e-18 66.8 1.3 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPS31836.1 - 6e-08 32.5 0.0 0.0032 17.2 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPS31836.1 - 1.1e-07 31.6 0.0 2.1e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Macoilin PF09726.4 EPS31836.1 - 0.0023 16.2 0.7 0.0076 14.5 0.0 1.8 1 1 1 2 2 2 1 Transmembrane protein Gryzun PF07919.7 EPS31837.1 - 1.9e-139 465.5 0.4 2.4e-139 465.2 0.3 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 EPS31837.1 - 7.5e-94 313.8 0.1 1.7e-83 279.9 0.3 2.2 2 0 0 2 2 2 2 Foie gras liver health family 1 Gryzun-like PF12742.2 EPS31837.1 - 0.005 16.6 0.0 0.0096 15.7 0.0 1.5 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking Reprolysin_4 PF13583.1 EPS31837.1 - 0.016 14.7 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like RXT2_N PF08595.6 EPS31838.1 - 2.3e-40 137.8 3.2 4e-40 137.0 0.0 2.6 2 0 0 2 2 2 1 RXT2-like, N-terminal Disaggr_repeat PF06848.6 EPS31838.1 - 0.081 12.3 0.1 0.14 11.5 0.1 1.3 1 0 0 1 1 1 0 Disaggregatase related repeat SH3_3 PF08239.6 EPS31839.1 - 0.0006 19.9 0.1 0.0014 18.7 0.0 1.6 1 1 0 1 1 1 1 Bacterial SH3 domain PEMT PF04191.8 EPS31840.1 - 3.8e-33 113.7 3.1 3.9e-33 113.7 1.2 1.7 2 0 0 2 2 2 1 Phospholipid methyltransferase YrhK PF14145.1 EPS31840.1 - 0.014 15.0 0.3 0.046 13.3 0.2 1.8 1 0 0 1 1 1 0 YrhK-like protein PXA PF02194.10 EPS31841.1 - 1.3e-48 165.0 0.1 1.3e-48 165.0 0.1 2.4 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.7 EPS31841.1 - 1.6e-26 92.5 0.8 9.4e-26 90.1 0.0 2.5 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 EPS31841.1 - 4.6e-22 77.9 0.2 1.1e-21 76.7 0.2 1.7 1 0 0 1 1 1 1 PX domain RGS PF00615.14 EPS31841.1 - 1.6e-09 37.9 0.1 3.9e-09 36.6 0.1 1.7 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF3759 PF12585.3 EPS31844.1 - 3.9e-37 126.0 2.3 4.4e-37 125.8 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) DUF3475 PF11961.3 EPS31845.1 - 0.0085 15.9 0.3 0.018 14.8 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3475) Hint_2 PF13403.1 EPS31845.1 - 0.099 12.5 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Hint domain WD40 PF00400.27 EPS31846.1 - 2.5e-27 93.6 4.7 1.4e-05 24.7 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat FliO PF04347.8 EPS31846.1 - 0.15 12.0 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Flagellar biosynthesis protein, FliO tRNA-synt_1g PF09334.6 EPS31847.1 - 1.9e-141 471.2 0.0 2.3e-141 470.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EPS31847.1 - 1.7e-08 32.9 0.2 1.9e-05 22.9 0.0 3.4 2 2 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EPS31847.1 - 0.0022 17.7 0.3 0.0055 16.4 0.0 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA RNase_H2-Ydr279 PF09468.5 EPS31847.1 - 0.008 15.4 0.4 0.012 14.8 0.3 1.2 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) Yae1_N PF09811.4 EPS31848.1 - 2.8e-06 26.7 2.1 4.2e-06 26.1 1.5 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal UPF0160 PF03690.8 EPS31849.1 - 2.6e-117 391.7 0.0 3e-117 391.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) ICE2 PF08426.5 EPS31850.1 - 5.9e-145 482.9 11.3 6.8e-145 482.7 7.8 1.0 1 0 0 1 1 1 1 ICE2 Endosulfine PF04667.12 EPS31852.1 - 1.5e-21 76.1 0.0 2.5e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region RNA_Me_trans PF04252.8 EPS31853.1 - 2.1e-47 161.1 0.0 2.5e-47 160.8 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase Peptidase_S10 PF00450.17 EPS31854.1 - 2.8e-113 379.2 0.0 3.8e-113 378.7 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EPS31854.1 - 9.2e-05 22.4 0.0 0.00036 20.4 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Act-Frag_cataly PF09192.5 EPS31854.1 - 0.097 11.6 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic Rifin_STEVOR PF02009.11 EPS31854.1 - 0.17 11.4 0.0 0.3 10.6 0.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family Lipase_3 PF01764.20 EPS31855.1 - 1.2e-37 128.7 0.1 4e-37 126.9 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) Lipase3_N PF03893.11 EPS31855.1 - 3.3e-05 23.6 0.3 6.5e-05 22.6 0.2 1.5 1 0 0 1 1 1 1 Lipase 3 N-terminal region Esterase PF00756.15 EPS31855.1 - 0.00068 19.1 0.1 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_8 PF06259.7 EPS31855.1 - 0.0037 16.7 0.0 0.0089 15.5 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase DUF2974 PF11187.3 EPS31855.1 - 0.0037 16.6 2.3 0.052 12.9 0.3 2.8 1 1 1 2 2 2 1 Protein of unknown function (DUF2974) PGAP1 PF07819.8 EPS31855.1 - 0.0038 16.8 0.0 0.0075 15.8 0.0 1.5 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EPS31855.1 - 0.0043 16.8 0.1 0.0064 16.2 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPS31855.1 - 0.0077 16.1 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EPS31855.1 - 0.0086 16.3 0.3 0.019 15.1 0.1 1.6 2 0 0 2 2 2 1 Thioesterase domain Phosphoesterase PF04185.9 EPS31856.1 - 2.3e-18 66.5 11.0 3.8e-17 62.5 3.4 2.4 2 1 1 3 3 3 2 Phosphoesterase family WD40 PF00400.27 EPS31857.1 - 2.7e-51 169.6 12.5 8e-10 38.2 0.0 7.6 7 1 0 7 7 7 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EPS31857.1 - 0.035 13.6 0.0 32 4.1 0.0 3.7 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain NRN1 PF15056.1 EPS31857.1 - 0.043 13.7 0.7 0.11 12.4 0.0 2.0 2 0 0 2 2 2 0 Neuritin protein family RNA_pol_3_Rpc31 PF11705.3 EPS31858.1 - 0.0044 16.9 8.2 0.005 16.8 5.7 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Pox_Ag35 PF03286.9 EPS31858.1 - 0.016 14.7 9.6 0.019 14.4 6.6 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Myc_N PF01056.13 EPS31858.1 - 0.017 14.3 6.4 0.018 14.2 4.4 1.1 1 0 0 1 1 1 0 Myc amino-terminal region RXT2_N PF08595.6 EPS31858.1 - 0.042 13.6 3.2 0.05 13.3 2.2 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal BAF1_ABF1 PF04684.8 EPS31858.1 - 0.045 12.5 0.1 0.047 12.5 0.1 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Nucleoplasmin PF03066.10 EPS31858.1 - 0.075 12.5 8.8 0.075 12.5 6.1 1.1 1 0 0 1 1 1 0 Nucleoplasmin TRAP_alpha PF03896.11 EPS31858.1 - 0.081 11.9 1.6 0.087 11.8 1.1 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit FAM177 PF14774.1 EPS31858.1 - 0.11 12.3 6.6 0.14 12.0 4.6 1.2 1 0 0 1 1 1 0 FAM177 family Paf1 PF03985.8 EPS31858.1 - 0.16 10.6 12.5 0.18 10.5 8.6 1.1 1 0 0 1 1 1 0 Paf1 DAP PF15228.1 EPS31858.1 - 0.17 12.6 6.7 0.096 13.4 3.5 1.4 1 1 0 1 1 1 0 Death-associated protein TLP-20 PF06088.6 EPS31858.1 - 0.2 11.3 2.7 0.23 11.1 1.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) BSP_II PF05432.6 EPS31858.1 - 0.31 10.2 13.1 0.34 10.1 9.1 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) FAM60A PF15396.1 EPS31858.1 - 0.46 10.2 2.9 0.46 10.2 2.0 1.0 1 0 0 1 1 1 0 Protein Family FAM60A PBP1_TM PF14812.1 EPS31858.1 - 0.68 10.2 12.4 1.2 9.5 8.6 1.4 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1510 PF07423.6 EPS31858.1 - 1.6 8.0 11.6 1.9 7.8 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) NPR3 PF03666.8 EPS31858.1 - 1.9 6.9 6.1 2.1 6.8 4.2 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Daxx PF03344.10 EPS31858.1 - 2.1 6.7 13.7 2.4 6.5 9.5 1.0 1 0 0 1 1 1 0 Daxx Family PBP_sp32 PF07222.7 EPS31858.1 - 2.5 7.2 12.4 2.9 6.9 8.6 1.1 1 0 0 1 1 1 0 Proacrosin binding protein sp32 VID27 PF08553.5 EPS31858.1 - 4.3 5.4 10.8 4.2 5.4 7.5 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Spore_coat_CotO PF14153.1 EPS31858.1 - 4.6 6.6 13.0 5.8 6.3 9.0 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DDHD PF02862.12 EPS31858.1 - 4.8 6.9 7.1 5.3 6.7 4.9 1.1 1 0 0 1 1 1 0 DDHD domain Tom37_C PF11801.3 EPS31858.1 - 7.1 6.4 6.8 10 5.9 4.7 1.3 1 1 0 1 1 1 0 Tom37 C-terminal domain FAM176 PF14851.1 EPS31858.1 - 7.3 6.2 10.8 7 6.3 7.0 1.3 1 1 0 1 1 1 0 FAM176 family Ycf1 PF05758.7 EPS31858.1 - 7.3 4.1 7.2 8 4.0 5.0 1.0 1 0 0 1 1 1 0 Ycf1 Adeno_terminal PF02459.10 EPS31858.1 - 8.2 4.4 9.5 9.9 4.1 6.6 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein CDC45 PF02724.9 EPS31858.1 - 8.9 4.1 8.5 10 4.0 5.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Tcp11 PF05794.8 EPS31859.1 - 2.7e-49 168.0 0.2 6.1e-49 166.9 0.0 1.6 2 0 0 2 2 2 1 T-complex protein 11 HTH_13 PF11972.3 EPS31859.1 - 0.087 12.6 0.0 0.37 10.6 0.0 2.1 1 0 0 1 1 1 0 HTH DNA binding domain zinc_ribbon_6 PF14599.1 EPS31860.1 - 4.3e-26 90.4 0.5 4.3e-26 90.4 0.4 3.8 4 0 0 4 4 4 1 Zinc-ribbon zf-CHY PF05495.7 EPS31860.1 - 9e-16 57.7 21.8 9e-16 57.7 15.1 4.3 2 1 0 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.1 EPS31860.1 - 4.2e-09 36.0 10.0 4.2e-09 36.0 7.0 4.4 3 1 2 5 5 5 1 Ring finger domain zf-C3HC4_3 PF13920.1 EPS31860.1 - 3.9e-07 29.6 8.5 3.9e-07 29.6 5.9 5.6 2 1 4 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EPS31860.1 - 2.8e-06 26.9 2.7 2.8e-06 26.9 1.8 2.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EPS31860.1 - 2.9e-06 27.1 7.7 2.9e-06 27.1 5.4 5.4 4 2 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPS31860.1 - 1.4e-05 24.7 8.7 1.4e-05 24.7 6.1 5.9 4 2 1 5 5 5 1 zinc-RING finger domain Complex1_LYR PF05347.10 EPS31861.1 - 3e-07 30.1 0.3 5.7e-07 29.2 0.2 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EPS31861.1 - 0.023 14.9 1.6 0.032 14.4 1.1 1.5 1 1 0 1 1 1 0 Complex1_LYR-like DUF2293 PF10056.4 EPS31862.1 - 9e-29 99.2 0.2 2.1e-28 98.1 0.2 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) HMA PF00403.21 EPS31863.1 - 3.7e-15 55.8 0.3 4.4e-15 55.5 0.2 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Rrn6 PF10214.4 EPS31864.1 - 5.7e-164 547.1 0.0 7e-164 546.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Spindle_Spc25 PF08234.7 EPS31865.1 - 1.4e-21 76.2 0.1 4.1e-21 74.7 0.0 1.8 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 Filament PF00038.16 EPS31865.1 - 0.031 13.7 18.1 0.069 12.5 12.6 1.6 1 1 0 1 1 1 0 Intermediate filament protein DegS PF05384.6 EPS31865.1 - 0.17 11.1 13.5 0.016 14.3 3.5 2.2 1 1 1 2 2 2 0 Sensor protein DegS DUF4140 PF13600.1 EPS31865.1 - 0.36 11.2 6.1 0.86 10.0 4.2 1.7 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) AHS1 PF02682.11 EPS31865.1 - 0.47 9.8 2.3 0.88 8.9 1.6 1.4 1 0 0 1 1 1 0 Allophanate hydrolase subunit 1 DUF3053 PF11254.3 EPS31865.1 - 2.7 7.1 11.7 2.2 7.4 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3053) Mnd1 PF03962.10 EPS31865.1 - 3.8 7.1 15.2 9.2 5.8 2.2 2.0 1 1 1 2 2 2 0 Mnd1 family Atg14 PF10186.4 EPS31865.1 - 5 5.9 11.3 7.9 5.3 7.8 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 WD40 PF00400.27 EPS31866.1 - 8.8e-32 107.8 13.9 4.4e-11 42.2 0.3 7.3 7 1 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EPS31866.1 - 0.00026 19.2 0.5 0.0034 15.6 0.0 2.4 2 1 0 2 2 2 1 Nucleoporin Nup120/160 Hira PF07569.6 EPS31866.1 - 0.00044 19.5 0.3 0.13 11.4 0.0 3.0 2 1 1 3 3 3 2 TUP1-like enhancer of split eIF2A PF08662.6 EPS31866.1 - 0.0013 18.5 0.1 0.023 14.4 0.0 2.6 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Lactonase PF10282.4 EPS31866.1 - 0.0015 17.6 0.0 0.76 8.8 0.0 2.3 1 1 0 2 2 2 2 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.11 EPS31866.1 - 0.0032 15.8 0.1 0.29 9.3 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain Coatomer_WDAD PF04053.9 EPS31866.1 - 0.041 12.6 0.0 0.049 12.4 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region Ribosomal_L32p PF01783.18 EPS31867.1 - 1.8e-13 50.4 7.2 2.1e-13 50.2 5.0 1.1 1 0 0 1 1 1 1 Ribosomal L32p protein family DZR PF12773.2 EPS31867.1 - 0.019 14.7 1.4 0.04 13.7 1.0 1.4 1 1 1 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.7 EPS31867.1 - 0.098 12.4 1.1 0.13 12.0 0.8 1.4 1 0 0 1 1 1 0 zinc-ribbons DUF1074 PF06382.6 EPS31867.1 - 0.24 11.3 3.0 0.27 11.1 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1074) Zn-ribbon_8 PF09723.5 EPS31867.1 - 0.71 9.8 3.9 1.6 8.7 0.1 2.2 1 1 1 2 2 2 0 Zinc ribbon domain zf-ribbon_3 PF13248.1 EPS31867.1 - 0.72 9.1 6.2 1.5 8.1 0.5 1.9 1 1 1 2 2 2 0 zinc-ribbon domain zf-FPG_IleRS PF06827.9 EPS31867.1 - 1.3 8.7 5.0 3.8 7.2 3.5 1.7 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS Septin PF00735.13 EPS31868.1 - 8.9e-113 375.9 0.7 1e-112 375.7 0.5 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EPS31868.1 - 1.7e-06 27.9 0.0 3.1e-06 27.1 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EPS31868.1 - 8.1e-06 25.0 0.0 1.5e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 EPS31868.1 - 8.3e-05 21.8 0.0 0.00015 20.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EPS31868.1 - 0.0002 20.8 0.4 0.012 15.0 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EPS31868.1 - 0.00059 19.6 0.6 1.3 8.8 0.0 2.5 1 1 1 2 2 2 2 Dynamin family AAA_10 PF12846.2 EPS31868.1 - 0.0017 17.8 0.2 0.0017 17.8 0.2 1.4 1 1 0 1 1 1 1 AAA-like domain AAA_23 PF13476.1 EPS31868.1 - 0.0088 16.3 0.0 0.015 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EPS31868.1 - 0.011 16.0 0.5 0.027 14.7 0.1 1.8 1 1 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.13 EPS31868.1 - 0.015 14.8 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Gtr1_RagA PF04670.7 EPS31868.1 - 0.019 14.1 0.1 0.14 11.2 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EPS31868.1 - 0.02 15.0 0.0 0.044 13.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EPS31868.1 - 0.02 13.7 0.0 0.036 12.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.1 EPS31868.1 - 0.03 14.3 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain T2SE PF00437.15 EPS31868.1 - 0.045 12.6 0.0 0.12 11.2 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein Miro PF08477.8 EPS31868.1 - 0.064 13.7 0.0 0.17 12.4 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein AAA_7 PF12775.2 EPS31868.1 - 0.067 12.2 0.0 1.2 8.1 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region D3 Guanylate_kin PF00625.16 EPS31869.1 - 1.8e-64 216.5 0.0 2.1e-64 216.3 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.1 EPS31869.1 - 1.1e-08 35.2 0.5 6.1e-08 32.8 0.3 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 EPS31869.1 - 1.1e-06 29.0 0.1 5.3e-06 26.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPS31869.1 - 2.4e-06 28.3 0.1 4.7e-05 24.1 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.1 EPS31869.1 - 5.4e-06 26.5 0.0 0.00011 22.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EPS31869.1 - 7.1e-06 25.9 0.0 3.4e-05 23.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EPS31869.1 - 2.7e-05 24.4 0.0 3.6e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_14 PF13173.1 EPS31869.1 - 4.6e-05 23.3 0.0 7.4e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EPS31869.1 - 0.00018 21.3 0.1 0.0004 20.1 0.0 1.9 1 1 0 1 1 1 1 Archaeal ATPase AAA_28 PF13521.1 EPS31869.1 - 0.00026 21.0 0.0 0.0015 18.4 0.0 2.1 1 1 1 2 2 2 1 AAA domain Rad17 PF03215.10 EPS31869.1 - 0.00039 19.2 0.0 0.00043 19.0 0.0 1.1 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein DUF258 PF03193.11 EPS31869.1 - 0.00061 19.0 0.0 0.0013 17.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 RNA_helicase PF00910.17 EPS31869.1 - 0.00085 19.4 0.0 0.0016 18.5 0.0 1.7 1 1 0 1 1 1 1 RNA helicase NACHT PF05729.7 EPS31869.1 - 0.0011 18.6 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Miro PF08477.8 EPS31869.1 - 0.0014 19.1 0.0 0.0022 18.4 0.0 1.5 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EPS31869.1 - 0.0016 18.3 0.0 0.0023 17.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_10 PF12846.2 EPS31869.1 - 0.0036 16.7 0.2 0.012 15.0 0.0 1.8 2 1 0 2 2 2 1 AAA-like domain Viral_helicase1 PF01443.13 EPS31869.1 - 0.0039 16.7 0.0 0.0059 16.1 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA PF00004.24 EPS31869.1 - 0.0076 16.4 0.1 0.023 14.9 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EPS31869.1 - 0.011 15.2 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2075 PF09848.4 EPS31869.1 - 0.011 14.6 0.0 0.41 9.5 0.0 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.9 EPS31869.1 - 0.016 14.9 0.2 0.1 12.3 0.0 2.3 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EPS31869.1 - 0.022 14.5 0.0 0.069 12.9 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain NTPase_1 PF03266.10 EPS31869.1 - 0.023 14.4 0.0 0.04 13.6 0.0 1.5 1 1 0 1 1 1 0 NTPase cobW PF02492.14 EPS31869.1 - 0.023 14.1 0.0 0.39 10.1 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 EPS31869.1 - 0.024 14.9 2.5 0.14 12.4 1.7 2.0 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EPS31869.1 - 0.057 12.2 0.0 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain DAP3 PF10236.4 EPS31869.1 - 0.059 12.3 0.0 0.084 11.7 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 T2SE PF00437.15 EPS31869.1 - 0.067 12.0 0.0 0.2 10.4 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_24 PF13479.1 EPS31869.1 - 0.09 12.3 0.3 0.44 10.0 0.0 2.0 1 1 1 2 2 2 0 AAA domain DUF3987 PF13148.1 EPS31869.1 - 0.097 11.2 0.5 0.41 9.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) MobB PF03205.9 EPS31869.1 - 0.1 12.3 0.0 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF1895 PF08988.5 EPS31869.1 - 0.11 12.6 0.1 0.19 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1895) AAA_25 PF13481.1 EPS31869.1 - 0.11 11.8 0.1 0.86 8.9 0.0 2.2 2 1 0 2 2 2 0 AAA domain KAP_NTPase PF07693.9 EPS31869.1 - 0.14 11.1 0.1 0.16 10.9 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain GRAB PF10375.4 EPS31870.1 - 4.9e-09 35.4 0.2 1.1e-08 34.3 0.1 1.7 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Reo_sigmaC PF04582.7 EPS31870.1 - 3.8e-07 29.6 14.3 2.7e-05 23.5 4.0 2.1 1 1 1 2 2 2 2 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 EPS31870.1 - 0.035 13.9 15.6 0.21 11.4 0.9 3.2 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4250 PF14056.1 EPS31870.1 - 0.14 11.9 6.8 1.3 8.8 0.1 3.8 3 1 1 4 4 4 0 Domain of unknown function (DUF4250) ApoO PF09769.4 EPS31870.1 - 0.27 10.9 14.5 1.1 8.9 1.2 3.7 1 1 2 3 3 3 0 Apolipoprotein O TMF_TATA_bd PF12325.3 EPS31870.1 - 0.29 10.8 51.8 0.1 12.3 3.1 4.4 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding Filament PF00038.16 EPS31870.1 - 1.6 8.1 52.1 8.4 5.7 18.8 2.9 1 1 1 2 2 2 0 Intermediate filament protein FlaC_arch PF05377.6 EPS31870.1 - 2.1 8.3 20.0 19 5.2 1.5 5.6 4 1 0 5 5 5 0 Flagella accessory protein C (FlaC) NPV_P10 PF05531.7 EPS31870.1 - 2.4 8.4 20.8 2.4 8.4 0.3 5.2 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 EPS31870.1 - 2.6 7.5 68.7 8.9 5.8 12.2 3.9 1 1 2 3 3 3 0 IncA protein Pox_A_type_inc PF04508.7 EPS31870.1 - 4.2 7.3 16.7 13 5.8 0.7 5.4 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Spc7 PF08317.6 EPS31870.1 - 4.3 5.8 48.3 4 6.0 18.2 2.9 1 1 1 2 2 2 0 Spc7 kinetochore protein HOOK PF05622.7 EPS31870.1 - 4.5 4.9 57.7 1 7.1 16.4 2.9 1 1 2 3 3 3 0 HOOK protein DAO PF01266.19 EPS31873.1 - 2.4e-48 164.8 0.0 3.4e-48 164.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPS31873.1 - 1.9e-09 36.8 0.4 5.7e-09 35.3 0.2 1.7 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EPS31873.1 - 3.7e-06 26.2 0.1 2.4e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EPS31873.1 - 0.0011 18.8 0.1 0.003 17.4 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EPS31873.1 - 0.0039 16.8 0.2 0.0073 15.9 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 EPS31873.1 - 0.0094 15.9 0.2 0.0094 15.9 0.1 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EPS31873.1 - 0.021 13.3 0.3 0.041 12.3 0.2 1.5 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 EPS31873.1 - 0.023 15.1 0.4 0.066 13.6 0.2 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EPS31873.1 - 0.08 11.7 0.6 0.29 9.9 0.4 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EPS31873.1 - 0.1 11.5 0.2 0.18 10.7 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein DUF2293 PF10056.4 EPS31875.1 - 0.09 12.7 0.1 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2293) FNIP_N PF14636.1 EPS31875.1 - 0.32 11.4 4.3 0.39 11.2 3.0 1.2 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus Ecl1 PF12855.2 EPS31876.1 - 3.2e-07 29.5 0.9 6.1e-07 28.6 0.6 1.5 1 0 0 1 1 1 1 Life-span regulatory factor Presenilin PF01080.12 EPS31876.1 - 1.3 7.7 3.6 1.4 7.6 2.5 1.0 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.4 EPS31876.1 - 2.9 6.6 6.6 3.1 6.5 4.5 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2217 PF10265.4 EPS31876.1 - 6.9 5.3 8.0 7.6 5.1 5.6 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DASH_Dad2 PF08654.5 EPS31879.1 - 1e-29 102.5 4.6 3.1e-28 97.7 3.2 2.0 1 1 0 1 1 1 1 DASH complex subunit Dad2 Shugoshin_N PF07558.6 EPS31880.1 - 1.5e-15 56.6 3.2 3.2e-15 55.5 2.2 1.6 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 EPS31880.1 - 5.2e-11 41.8 5.7 5.2e-11 41.8 3.9 3.5 3 0 0 3 3 3 1 Shugoshin C terminus Snapin_Pallidin PF14712.1 EPS31880.1 - 0.0088 16.3 0.6 0.018 15.3 0.4 1.5 1 0 0 1 1 1 1 Snapin/Pallidin DivIC PF04977.10 EPS31880.1 - 0.026 13.9 0.5 0.14 11.6 0.2 2.3 2 0 0 2 2 2 0 Septum formation initiator GAS PF13851.1 EPS31880.1 - 0.034 13.3 0.6 0.069 12.3 0.4 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.3 EPS31880.1 - 0.035 13.8 1.3 0.1 12.3 0.9 1.8 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding bZIP_1 PF00170.16 EPS31880.1 - 0.037 13.9 0.6 0.037 13.9 0.4 3.2 4 0 0 4 4 4 0 bZIP transcription factor bZIP_2 PF07716.10 EPS31880.1 - 0.041 13.7 0.7 0.041 13.7 0.5 2.8 3 0 0 3 3 3 0 Basic region leucine zipper PPI_Ypi1 PF07491.6 EPS31881.1 - 1.9e-26 91.4 2.2 4.5e-26 90.2 1.6 1.7 1 1 0 1 1 1 1 Protein phosphatase inhibitor CDC45 PF02724.9 EPS31881.1 - 2.1 6.3 4.7 2.3 6.1 3.2 1.1 1 0 0 1 1 1 0 CDC45-like protein CRM1_C PF08767.6 EPS31882.1 - 1.6e-134 447.8 7.7 1.6e-134 447.8 5.3 3.3 4 1 1 5 5 5 1 CRM1 C terminal Xpo1 PF08389.7 EPS31882.1 - 8.7e-42 142.5 6.0 8.7e-42 142.5 4.1 3.9 5 0 0 5 5 5 1 Exportin 1-like protein IBN_N PF03810.14 EPS31882.1 - 2.2e-11 43.4 0.0 1.2e-10 41.1 0.0 2.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.3 EPS31882.1 - 0.012 15.5 0.5 0.13 12.2 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) HD_assoc PF13286.1 EPS31882.1 - 0.12 12.6 2.3 9.8 6.5 0.1 4.3 4 1 1 5 5 5 0 Phosphohydrolase-associated domain uDENN PF03456.13 EPS31882.1 - 0.14 12.1 0.5 1.1 9.2 0.1 2.7 3 0 0 3 3 3 0 uDENN domain Mac PF12464.3 EPS31885.1 - 4.3e-13 49.0 0.2 8.6e-13 48.1 0.1 1.5 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.1 EPS31885.1 - 7.5e-11 41.3 4.7 0.0001 21.8 0.1 2.7 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Zn_clus PF00172.13 EPS31885.1 - 1e-09 38.1 8.2 1.9e-09 37.2 5.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexapep PF00132.19 EPS31885.1 - 7.6e-09 34.6 7.6 0.00015 21.1 0.2 3.6 4 0 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Mitofilin PF09731.4 EPS31885.1 - 0.088 11.4 9.1 0.14 10.7 6.3 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein NmrA PF05368.8 EPS31886.1 - 3.9e-07 29.5 0.0 1.7e-06 27.4 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPS31886.1 - 0.00091 19.2 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding DUF1840 PF08895.6 EPS31886.1 - 0.12 12.3 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) Zn_clus PF00172.13 EPS31887.1 - 1.7e-08 34.2 11.6 1.7e-08 34.2 8.0 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EPS31887.1 - 4.6e-07 28.9 0.4 2.7e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 EPS31887.1 - 0.0042 17.3 8.1 0.26 11.6 0.9 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 EPS31887.1 - 0.0048 17.1 0.7 0.0048 17.1 0.5 4.3 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPS31887.1 - 0.0076 16.5 10.2 0.015 15.6 1.4 4.9 5 1 0 5 5 5 2 C2H2-type zinc finger Fungal_trans PF04082.13 EPS31888.1 - 1.3e-08 34.0 0.2 1.8e-08 33.5 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EPS31889.1 - 9e-07 28.8 9.8 0.0099 16.1 0.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EPS31889.1 - 9.9e-05 22.4 11.5 0.00057 20.0 1.9 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EPS31889.1 - 0.0019 18.4 8.8 0.44 11.0 0.3 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger Ribonuc_L-PSP PF01042.16 EPS31890.1 - 3.1e-19 68.9 0.0 3.9e-19 68.5 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP ALAD PF00490.16 EPS31891.1 - 1.4e-118 395.5 0.0 1.6e-118 395.3 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase A_deaminase PF00962.17 EPS31897.1 - 5.6e-112 373.9 0.0 7.4e-112 373.5 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase Dynamin_M PF01031.15 EPS31899.1 - 3.2e-113 377.3 0.0 5.4e-113 376.6 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EPS31899.1 - 5.8e-54 182.4 0.0 1.3e-53 181.2 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EPS31899.1 - 3.7e-31 106.8 0.7 3.7e-31 106.8 0.5 2.2 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EPS31899.1 - 0.00063 19.6 0.1 0.0052 16.7 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EPS31899.1 - 0.016 15.7 0.0 0.041 14.3 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein FeoB_N PF02421.13 EPS31899.1 - 0.04 13.1 0.1 2.5 7.3 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B zf-CCHC_4 PF14392.1 EPS31899.1 - 0.1 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Zinc knuckle UAA PF08449.6 EPS31900.1 - 1.7e-77 260.3 10.2 3e-77 259.5 7.0 1.3 1 1 0 1 1 1 1 UAA transporter family Tmemb_18A PF09771.4 EPS31900.1 - 0.0015 18.5 3.1 0.039 13.9 0.2 2.6 2 0 0 2 2 2 2 Transmembrane protein 188 EmrE PF13536.1 EPS31900.1 - 0.0058 16.8 3.6 0.0058 16.8 2.5 3.4 3 2 1 4 4 4 2 Multidrug resistance efflux transporter TPT PF03151.11 EPS31900.1 - 0.28 10.8 20.5 0.015 14.9 8.2 2.8 2 2 0 2 2 2 0 Triose-phosphate Transporter family Rad17 PF03215.10 EPS31901.1 - 6.8e-59 199.9 0.0 9.4e-59 199.4 0.0 1.1 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 EPS31901.1 - 0.00076 19.1 0.0 0.0025 17.5 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EPS31901.1 - 0.0012 19.6 0.0 0.0027 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPS31901.1 - 0.0032 17.4 0.0 0.0076 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 EPS31901.1 - 0.0093 16.1 0.0 0.022 14.9 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EPS31901.1 - 0.02 14.4 0.0 0.049 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EPS31901.1 - 0.026 14.1 0.1 0.7 9.5 0.1 2.9 3 0 0 3 3 3 0 NACHT domain AAA_18 PF13238.1 EPS31901.1 - 0.039 14.2 0.0 0.078 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EPS31901.1 - 0.07 13.2 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EPS31901.1 - 0.091 12.9 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_33 PF13671.1 EPS31901.1 - 0.093 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EPS31901.1 - 0.12 11.2 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF4177 PF13783.1 EPS31901.1 - 0.15 11.6 0.0 0.42 10.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4177) DUF566 PF04484.7 EPS31901.1 - 2.3 7.6 16.2 4.9 6.5 11.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF566) ELMO_CED12 PF04727.8 EPS31902.1 - 1.4e-48 164.6 0.0 2.2e-48 164.0 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 EPS31902.1 - 2e-05 24.3 0.0 0.00034 20.3 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) DUF3552 PF12072.3 EPS31902.1 - 0.1 11.7 0.2 0.18 10.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF1752 PF08550.5 EPS31903.1 - 2e-11 43.2 2.9 3.9e-11 42.3 2.0 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF1325 PF07039.6 EPS31903.1 - 0.027 14.0 0.1 0.091 12.3 0.0 1.8 2 0 0 2 2 2 0 SGF29 tudor-like domain SUI1 PF01253.17 EPS31906.1 - 1.1e-21 76.4 0.4 1.9e-21 75.6 0.3 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 Herpes_BLRF2 PF05812.7 EPS31906.1 - 0.011 15.5 3.9 1.8 8.4 0.4 2.3 2 1 0 2 2 2 0 Herpesvirus BLRF2 protein TnpV PF14198.1 EPS31906.1 - 0.019 14.8 0.1 0.032 14.1 0.1 1.4 1 0 0 1 1 1 0 Transposon-encoded protein TnpV PhoD PF09423.5 EPS31906.1 - 0.046 12.2 0.0 0.046 12.2 0.0 1.1 1 0 0 1 1 1 0 PhoD-like phosphatase TRSP PF12500.3 EPS31906.1 - 0.068 12.6 0.1 0.091 12.2 0.0 1.2 1 0 0 1 1 1 0 TRSP domain C terminus to PRTase_2 Apc4 PF12896.2 EPS31906.1 - 0.081 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 SH2_2 PF14633.1 EPS31906.1 - 0.14 11.1 0.7 0.25 10.3 0.2 1.6 2 0 0 2 2 2 0 SH2 domain LMBR1 PF04791.11 EPS31906.1 - 0.2 10.2 0.9 0.24 9.9 0.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein HK97-gp10_like PF04883.7 EPS31906.1 - 8.9 7.3 7.8 28 5.7 5.3 2.0 1 1 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component BicD PF09730.4 EPS31907.1 - 0.0015 17.0 0.2 0.002 16.6 0.2 1.1 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D GAS PF13851.1 EPS31907.1 - 0.0057 15.8 2.8 0.0057 15.8 1.9 1.6 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding AAA_27 PF13514.1 EPS31907.1 - 0.021 12.5 7.4 0.19 9.3 5.1 2.0 1 1 0 1 1 1 0 AAA domain FbpA PF05833.6 EPS31907.1 - 0.041 12.4 3.4 0.86 8.0 0.2 2.1 1 1 1 2 2 2 0 Fibronectin-binding protein A N-terminus (FbpA) MtrB PF05440.7 EPS31907.1 - 0.042 13.8 0.0 0.87 9.6 0.0 2.5 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B Baculo_PEP_C PF04513.7 EPS31907.1 - 0.054 13.3 1.3 0.2 11.5 0.7 1.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA_13 PF13166.1 EPS31907.1 - 0.06 11.8 3.1 0.085 11.2 2.2 1.1 1 0 0 1 1 1 0 AAA domain MitMem_reg PF13012.1 EPS31907.1 - 0.065 13.3 1.9 0.22 11.6 0.2 2.4 1 1 2 3 3 3 0 Maintenance of mitochondrial structure and function DUF2884 PF11101.3 EPS31907.1 - 0.078 12.3 1.1 0.13 11.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) CENP-F_leu_zip PF10473.4 EPS31907.1 - 0.1 12.4 7.4 0.045 13.6 3.1 1.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FUSC PF04632.7 EPS31907.1 - 0.13 10.6 5.1 0.21 9.9 3.5 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family TPR_MLP1_2 PF07926.7 EPS31907.1 - 0.15 11.8 4.9 0.38 10.4 3.4 1.7 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF607 PF04678.8 EPS31907.1 - 0.16 11.8 1.9 0.44 10.4 0.8 2.1 1 1 0 1 1 1 0 Protein of unknown function, DUF607 DUF948 PF06103.6 EPS31907.1 - 0.17 11.7 0.1 1.8 8.4 0.0 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Tropomyosin_1 PF12718.2 EPS31907.1 - 0.69 9.7 6.5 0.47 10.2 2.7 2.0 1 1 1 2 2 2 0 Tropomyosin like Nup54 PF13874.1 EPS31907.1 - 0.81 9.3 6.6 0.39 10.3 0.5 2.5 1 1 0 2 2 2 0 Nucleoporin complex subunit 54 Spectrin PF00435.16 EPS31907.1 - 0.94 9.8 6.8 15 5.9 2.2 2.5 1 1 1 2 2 2 0 Spectrin repeat DUF3552 PF12072.3 EPS31907.1 - 2 7.6 7.1 1.3 8.2 3.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) Syntaxin PF00804.20 EPS31907.1 - 3 8.0 10.5 22 5.3 4.5 3.1 1 1 1 2 2 2 0 Syntaxin Cgr1 PF03879.9 EPS31908.1 - 7.8e-40 135.4 28.2 9.2e-40 135.2 19.5 1.0 1 0 0 1 1 1 1 Cgr1 family Y2_Tnp PF04986.8 EPS31908.1 - 0.12 12.0 4.5 0.16 11.7 3.1 1.1 1 0 0 1 1 1 0 Putative transposase PRP1_N PF06424.7 EPS31908.1 - 0.21 11.8 11.6 0.26 11.5 8.1 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal CLPTM1 PF05602.7 EPS31908.1 - 0.38 9.4 2.0 0.39 9.3 1.4 1.1 1 0 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) Asp-B-Hydro_N PF05279.6 EPS31908.1 - 0.39 10.5 9.5 0.41 10.4 6.6 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SprA-related PF12118.3 EPS31908.1 - 0.55 9.5 13.8 0.65 9.2 9.6 1.0 1 0 0 1 1 1 0 SprA-related family DUF4192 PF13830.1 EPS31908.1 - 0.77 9.3 5.8 0.77 9.3 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4192) CDC27 PF09507.5 EPS31908.1 - 1.3 8.1 18.2 1.5 7.9 12.6 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 VIT1 PF01988.14 EPS31908.1 - 2.6 7.4 7.3 3.3 7.1 5.1 1.1 1 0 0 1 1 1 0 VIT family DDRGK PF09756.4 EPS31908.1 - 3.2 7.1 21.1 3.9 6.8 14.6 1.2 1 0 0 1 1 1 0 DDRGK domain RR_TM4-6 PF06459.7 EPS31908.1 - 3.8 7.3 12.9 4.2 7.1 8.9 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2058 PF09831.4 EPS31908.1 - 4.2 7.2 17.6 5.9 6.7 12.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) DDHD PF02862.12 EPS31908.1 - 8.8 6.0 9.0 10 5.8 6.2 1.1 1 0 0 1 1 1 0 DDHD domain Mito_carr PF00153.22 EPS31909.1 - 2.6e-65 216.1 0.7 8.2e-23 79.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein dCMP_cyt_deam_1 PF00383.17 EPS31910.1 - 1.7e-14 53.3 0.6 2e-14 53.0 0.4 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 EPS31910.1 - 2e-11 43.9 0.9 7.2e-10 38.9 0.1 2.0 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 EPS31910.1 - 0.00067 19.0 0.4 0.85 8.9 0.0 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases BNR PF02012.15 EPS31911.1 - 0.00017 20.9 30.7 0.48 10.4 0.1 9.3 10 0 0 10 10 10 5 BNR/Asp-box repeat DUF2167 PF09935.4 EPS31911.1 - 0.017 13.9 0.1 0.41 9.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2167) KAR9 PF08580.5 EPS31912.1 - 4.1 5.5 11.0 0.38 8.9 0.1 2.3 2 1 0 2 2 2 0 Yeast cortical protein KAR9 Sec10 PF07393.6 EPS31915.1 - 1.1e-232 774.1 0.0 1.3e-232 773.9 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 Apolipoprotein PF01442.13 EPS31915.1 - 0.079 12.4 5.2 7.9 5.9 0.4 3.6 2 1 0 3 3 3 0 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.7 EPS31915.1 - 0.18 11.6 3.0 6.6 6.5 0.1 3.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Prenyltransf PF01255.14 EPS31916.1 - 0.0071 15.4 0.0 0.054 12.6 0.0 2.3 2 1 0 2 2 2 1 Putative undecaprenyl diphosphate synthase Fungal_trans PF04082.13 EPS31919.1 - 5.4e-21 74.6 0.0 9.7e-21 73.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS31919.1 - 2.8e-07 30.3 12.8 4.6e-07 29.6 8.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fringe PF02434.11 EPS31920.1 - 4.8e-08 32.5 0.6 6.1e-05 22.3 0.1 3.1 2 1 0 2 2 2 2 Fringe-like PAN_1 PF00024.21 EPS31920.1 - 2.8e-05 23.7 0.1 6.1e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.1 EPS31920.1 - 0.00032 20.3 0.6 0.00077 19.1 0.4 1.7 1 0 0 1 1 1 1 PAN domain MFS_1 PF07690.11 EPS31921.1 - 5.6e-23 81.2 62.6 1.3e-21 76.7 31.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Herpes_UL69 PF05459.7 EPS31921.1 - 0.12 11.4 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Herpesvirus transcriptional regulator family Methyltransf_2 PF00891.13 EPS31922.1 - 1.1e-15 57.5 0.0 2.1e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 O-methyltransferase DUF2868 PF11067.3 EPS31922.1 - 0.0096 15.0 0.1 0.013 14.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2868) DUF1115 PF06544.7 EPS31924.1 - 0.018 14.7 0.6 0.037 13.7 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1115) Spt5-NGN PF03439.8 EPS31924.1 - 0.061 13.0 0.1 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 Early transcription elongation factor of RNA pol II, NGN section MFS_1 PF07690.11 EPS31925.1 - 1.2e-33 116.3 33.3 2.5e-32 111.9 23.1 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2762 PF10960.3 EPS31925.1 - 0.0059 16.2 0.0 0.015 14.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2762) ESSS PF10183.4 EPS31925.1 - 0.015 15.6 0.2 0.06 13.7 0.1 2.1 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Epiglycanin_C PF14654.1 EPS31926.1 - 0.086 12.8 1.3 7 6.7 0.7 2.5 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region FAD_binding_3 PF01494.14 EPS31928.1 - 8.4e-14 51.3 0.0 0.0014 17.7 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 EPS31928.1 - 1.1e-06 28.5 0.1 3.5e-06 26.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EPS31928.1 - 0.00054 19.1 0.0 0.00097 18.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EPS31928.1 - 0.00087 18.2 0.0 0.08 11.8 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EPS31928.1 - 0.0019 18.5 0.0 0.16 12.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EPS31928.1 - 0.047 12.7 0.1 6.6 5.6 0.0 2.5 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase HI0933_like PF03486.9 EPS31928.1 - 0.12 10.8 0.0 3.4 6.0 0.0 2.4 2 0 0 2 2 2 0 HI0933-like protein Fungal_trans PF04082.13 EPS31929.1 - 6.7e-24 84.1 1.0 1.2e-23 83.3 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS31929.1 - 1.7e-07 30.9 8.0 3.9e-07 29.8 5.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Na_H_Exchanger PF00999.16 EPS31930.1 - 5.4e-33 114.0 12.1 7.4e-33 113.5 8.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 EPS31930.1 - 0.045 13.6 0.2 0.17 11.8 0.1 2.0 1 0 0 1 1 1 0 YrhC-like protein MAPEG PF01124.13 EPS31931.1 - 3.5e-14 52.5 1.9 6.3e-14 51.6 1.3 1.4 1 1 0 1 1 1 1 MAPEG family Glyco_hydro_28 PF00295.12 EPS31932.1 - 8.7e-50 169.5 4.1 1.2e-49 169.0 2.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 YabP PF07873.6 EPS31932.1 - 0.016 14.7 1.4 0.037 13.5 0.1 2.2 3 0 0 3 3 3 0 YabP family DUF4528 PF15031.1 EPS31932.1 - 0.021 14.5 0.0 0.056 13.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4528) MFS_1 PF07690.11 EPS31933.1 - 1.1e-31 109.8 33.8 1.1e-31 109.8 23.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS31933.1 - 8.5e-10 37.7 11.9 8.5e-10 37.7 8.3 3.1 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EPS31933.1 - 1.1e-05 23.8 6.5 1.1e-05 23.8 4.5 2.3 2 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MMPL PF03176.10 EPS31933.1 - 0.032 12.9 0.3 0.032 12.9 0.2 2.3 2 0 0 2 2 2 0 MMPL family p450 PF00067.17 EPS31935.1 - 1.4e-70 238.1 0.0 1.9e-70 237.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 EPS31936.1 - 4.8e-23 81.9 0.1 1.5e-22 80.3 0.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPS31936.1 - 1.2e-08 35.0 0.0 1.7e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPS31936.1 - 6.8e-07 29.1 1.9 1.3e-05 24.9 0.8 2.5 2 1 0 2 2 2 1 KR domain Epimerase PF01370.16 EPS31936.1 - 0.0021 17.5 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family UPF0146 PF03686.8 EPS31936.1 - 0.02 14.7 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) NAD_binding_10 PF13460.1 EPS31936.1 - 0.021 14.8 0.0 0.077 12.9 0.0 1.8 2 0 0 2 2 2 0 NADH(P)-binding 2-Hacid_dh_C PF02826.14 EPS31936.1 - 0.063 12.4 0.0 0.093 11.8 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Abhydrolase_3 PF07859.8 EPS31937.1 - 1e-23 84.0 0.0 1.5e-23 83.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EPS31937.1 - 3.7e-15 55.4 0.0 5.8e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EPS31937.1 - 6.3e-06 26.0 0.0 1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EPS31937.1 - 0.008 15.4 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2974 PF11187.3 EPS31937.1 - 0.018 14.3 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF1609 PF07753.6 EPS31937.1 - 0.19 11.0 0.0 0.26 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1609) Pyr_redox_3 PF13738.1 EPS31938.1 - 2e-28 99.8 0.0 5.5e-28 98.4 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EPS31938.1 - 1.1e-20 73.3 0.0 1.1e-18 66.7 0.0 2.2 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EPS31938.1 - 3.2e-12 46.2 0.0 6.5e-09 35.6 0.0 3.3 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EPS31938.1 - 2.2e-10 40.0 0.1 2.4e-08 33.2 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EPS31938.1 - 5.4e-08 32.1 0.4 6.8e-05 21.9 0.1 2.9 4 0 0 4 4 4 2 FAD dependent oxidoreductase Thi4 PF01946.12 EPS31938.1 - 3.5e-07 29.5 0.0 0.00031 19.9 0.0 2.5 3 0 0 3 3 3 2 Thi4 family Pyr_redox_2 PF07992.9 EPS31938.1 - 1.1e-06 28.6 0.9 0.081 12.7 0.1 3.2 2 2 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EPS31938.1 - 2.6e-06 26.6 0.0 0.0041 16.0 0.0 3.7 4 0 0 4 4 4 1 Lycopene cyclase protein Pyr_redox PF00070.22 EPS31938.1 - 8.6e-05 22.8 0.0 0.012 15.9 0.0 3.0 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPS31938.1 - 0.00033 20.4 0.3 1.3 8.8 0.0 3.7 3 1 0 3 3 3 2 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EPS31938.1 - 0.006 16.6 0.0 0.038 14.1 0.0 2.1 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 EPS31938.1 - 0.0082 15.0 0.0 0.2 10.4 0.0 2.7 3 0 0 3 3 3 1 FAD binding domain NAD_binding_7 PF13241.1 EPS31938.1 - 0.027 14.7 0.0 0.075 13.2 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding GIDA PF01134.17 EPS31938.1 - 0.087 11.6 0.3 7.9 5.2 0.0 2.5 3 0 0 3 3 3 0 Glucose inhibited division protein A ApbA PF02558.11 EPS31938.1 - 0.11 11.9 0.2 0.4 10.1 0.0 2.1 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Mqo PF06039.10 EPS31938.1 - 0.2 9.7 0.1 3.7 5.6 0.0 2.3 2 1 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) Crp PF00325.15 EPS31938.1 - 2.3 7.7 5.2 0.36 10.3 0.1 2.2 2 0 0 2 2 2 0 Bacterial regulatory proteins, crp family PTR2 PF00854.16 EPS31940.1 - 1.3e-41 142.6 12.4 2.5e-41 141.6 7.2 2.4 1 1 1 2 2 2 1 POT family OSTbeta PF15048.1 EPS31940.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein DUF4251 PF14059.1 EPS31941.1 - 0.11 12.3 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4251) DUF1762 PF08574.5 EPS31943.1 - 9.8e-20 70.7 10.7 9.8e-20 70.7 7.4 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1762) RRM_6 PF14259.1 EPS31945.1 - 5.3e-40 135.2 0.0 9.4e-11 41.5 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPS31945.1 - 2.2e-39 132.8 0.0 7e-12 44.8 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS31945.1 - 4.9e-19 67.9 0.0 1.8e-05 24.4 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.4 EPS31945.1 - 1.1e-13 50.4 3.9 6.6e-13 48.0 2.7 2.4 1 0 0 1 1 1 1 Putative RRM domain RRM_3 PF08777.6 EPS31945.1 - 2.2e-05 24.2 0.0 0.092 12.6 0.0 2.6 2 0 0 2 2 2 2 RNA binding motif RNA_bind PF08675.6 EPS31945.1 - 0.018 15.0 0.0 0.58 10.1 0.0 3.0 3 0 0 3 3 3 0 RNA binding domain tRNA-synt_2 PF00152.15 EPS31948.1 - 1.1e-72 244.6 0.0 1.7e-72 244.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EPS31948.1 - 6.4e-07 29.1 0.0 1.2e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain MAD PF05557.8 EPS31948.1 - 0.0014 16.8 1.0 0.002 16.3 0.7 1.1 1 0 0 1 1 1 1 Mitotic checkpoint protein DUF935 PF06074.7 EPS31950.1 - 0.039 12.6 0.2 0.043 12.5 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF935) Fungal_trans PF04082.13 EPS31954.1 - 6.3e-22 77.6 0.1 1.6e-21 76.3 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS31954.1 - 0.029 14.2 3.7 0.055 13.3 2.6 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 EPS31955.1 - 3.5e-05 23.1 0.0 0.00017 20.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS31955.1 - 0.0013 17.8 0.0 0.0014 17.7 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPS31955.1 - 0.0038 16.9 0.5 0.011 15.4 0.3 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Prd1-P2 PF09214.6 EPS31955.1 - 0.13 10.8 0.1 0.19 10.2 0.1 1.2 1 0 0 1 1 1 0 Bacteriophage Prd1, adsorption protein P2 Aldo_ket_red PF00248.16 EPS31956.1 - 1.2e-52 178.4 0.0 1.4e-52 178.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NmrA PF05368.8 EPS31956.1 - 0.0066 15.7 0.2 0.011 15.0 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family Ecl1 PF12855.2 EPS31958.1 - 6.2e-16 57.4 1.0 9.5e-16 56.8 0.7 1.3 1 0 0 1 1 1 1 Life-span regulatory factor DUF581 PF04570.9 EPS31958.1 - 0.00099 18.3 0.6 0.0021 17.3 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF581) zf-MYND PF01753.13 EPS31958.1 - 0.0029 17.4 0.6 0.007 16.2 0.4 1.5 1 0 0 1 1 1 1 MYND finger DUF2256 PF10013.4 EPS31958.1 - 1.4 8.6 5.3 0.92 9.3 0.6 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) YL1 PF05764.8 EPS31959.1 - 3.1e-62 210.3 18.6 3.1e-62 210.3 12.9 3.1 2 1 0 3 3 3 1 YL1 nuclear protein YL1_C PF08265.6 EPS31959.1 - 3.2e-12 45.7 0.2 5.7e-12 44.9 0.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain PUF PF00806.14 EPS31961.1 - 7.1e-25 85.0 0.0 8.8e-05 21.7 0.0 6.1 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 EPS31961.1 - 6.8e-10 38.4 0.0 1.4e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS31961.1 - 2.6e-07 30.3 0.0 5.8e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS31961.1 - 9.8e-05 22.2 0.0 0.00023 21.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MT-A70 PF05063.9 EPS31962.1 - 1.9e-18 66.6 0.0 1.8e-14 53.6 0.0 2.4 1 1 0 2 2 2 2 MT-A70 MFS_1 PF07690.11 EPS31963.1 - 4.9e-37 127.4 51.1 4.9e-37 127.4 35.4 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Peptidase_C12 PF01088.16 EPS31964.1 - 1.7e-65 220.1 0.0 2.1e-65 219.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Glyoxalase_2 PF12681.2 EPS31964.1 - 0.13 12.8 0.1 0.24 12.0 0.0 1.6 1 1 0 1 1 1 0 Glyoxalase-like domain DcpS PF05652.7 EPS31965.1 - 7e-31 106.8 0.0 1.2e-30 106.1 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.3 EPS31965.1 - 1.8e-30 105.5 0.1 3.1e-30 104.7 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding RNase_H2_suC PF08615.6 EPS31966.1 - 3.4e-31 107.9 0.0 4.3e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Nop53 PF07767.6 EPS31967.1 - 6.9e-119 397.2 32.5 8.7e-119 396.9 22.5 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) FLO_LFY PF01698.11 EPS31967.1 - 0.066 12.0 15.6 0.13 11.0 10.8 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein Myb_Cef PF11831.3 EPS31968.1 - 1.9e-69 233.4 2.5 1.9e-69 233.4 1.8 3.3 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 EPS31968.1 - 7e-21 74.0 4.7 2.3e-09 37.1 0.2 3.5 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EPS31968.1 - 9.3e-20 70.4 4.8 2.8e-13 49.7 0.8 3.4 2 1 1 3 3 3 2 Myb-like DNA-binding domain HTH_AsnC-type PF13404.1 EPS31968.1 - 0.018 14.5 2.6 0.23 10.9 0.0 2.9 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain MOZ_SAS PF01853.13 EPS31969.1 - 6.1e-83 276.6 0.0 8.7e-83 276.1 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EPS31969.1 - 2.2e-23 81.7 0.0 5.7e-23 80.3 0.0 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 EPS31969.1 - 0.052 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Aa_trans PF01490.13 EPS31970.1 - 6.2e-25 87.5 34.3 5e-24 84.5 23.7 2.1 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein F1F0-ATPsyn_F PF10791.4 EPS31975.1 - 5.2e-39 132.3 0.3 5.8e-39 132.2 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 EPS31975.1 - 0.0095 15.9 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f ETC_C1_NDUFA4 PF04800.7 EPS31976.1 - 3.1e-38 129.6 0.9 5.5e-38 128.9 0.6 1.4 1 0 0 1 1 1 1 ETC complex I subunit conserved region DUF2188 PF09954.4 EPS31976.1 - 0.034 14.0 0.1 0.074 12.9 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) HEAT_2 PF13646.1 EPS31977.1 - 7.5e-31 106.2 0.9 3e-14 53.0 0.0 3.6 2 2 2 4 4 4 2 HEAT repeats HEAT_PBS PF03130.11 EPS31977.1 - 1.9e-17 61.9 10.3 0.0052 17.1 0.3 7.2 8 0 0 8 8 8 5 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 EPS31977.1 - 6.4e-09 36.0 4.4 0.061 13.8 0.1 5.4 4 2 1 5 5 5 4 HEAT-like repeat HEAT PF02985.17 EPS31977.1 - 1.2e-07 31.2 1.2 5.6 7.3 0.0 6.1 6 1 0 6 6 6 2 HEAT repeat RuvA_C PF07499.8 EPS31977.1 - 0.011 15.9 1.5 1.7 8.9 0.1 3.2 3 0 0 3 3 3 0 RuvA, C-terminal domain Cohesin_HEAT PF12765.2 EPS31977.1 - 0.045 13.7 0.2 1.7 8.7 0.0 3.3 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion TFIIS_C PF01096.13 EPS31978.1 - 5e-14 51.6 1.3 5e-14 51.6 0.9 3.3 4 0 0 4 4 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EPS31978.1 - 4e-07 29.6 0.5 4e-07 29.6 0.3 2.8 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit RRN7 PF11781.3 EPS31978.1 - 0.002 17.5 0.9 3.2 7.3 0.0 3.4 3 0 0 3 3 3 1 RNA polymerase I-specific transcription initiation factor Rrn7 DZR PF12773.2 EPS31978.1 - 0.0064 16.2 4.5 0.073 12.9 0.5 2.4 1 1 1 2 2 2 2 Double zinc ribbon zinc_ribbon_2 PF13240.1 EPS31978.1 - 0.025 14.0 8.2 0.25 10.8 0.5 3.5 3 1 0 3 3 3 0 zinc-ribbon domain Zn_ribbon_recom PF13408.1 EPS31978.1 - 0.034 14.4 7.9 0.63 10.3 0.6 2.7 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain GFA PF04828.9 EPS31978.1 - 0.059 13.3 6.4 0.3 11.0 1.3 2.4 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme C1_1 PF00130.17 EPS31978.1 - 0.11 12.2 0.1 0.11 12.2 0.1 2.0 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) TF_Zn_Ribbon PF08271.7 EPS31978.1 - 0.15 11.4 8.3 0.93 8.8 0.1 3.5 4 0 0 4 4 4 0 TFIIB zinc-binding Lar_restr_allev PF14354.1 EPS31978.1 - 0.28 11.5 7.4 8.5 6.7 0.6 3.0 1 1 1 2 2 2 0 Restriction alleviation protein Lar Ribosomal_S27e PF01667.12 EPS31978.1 - 0.29 10.7 3.1 3.2 7.3 0.0 3.0 2 1 1 3 3 3 0 Ribosomal protein S27 zf-ribbon_3 PF13248.1 EPS31978.1 - 0.32 10.2 5.7 12 5.2 0.0 3.6 4 0 0 4 4 4 0 zinc-ribbon domain RNHCP PF12647.2 EPS31978.1 - 0.35 10.7 4.8 1.6 8.6 1.8 2.4 1 1 0 1 1 1 0 RNHCP domain IBR PF01485.16 EPS31978.1 - 0.57 10.1 0.1 0.57 10.1 0.1 2.2 2 1 0 2 2 2 0 IBR domain zf-trcl PF13451.1 EPS31978.1 - 0.64 9.6 4.3 12 5.6 0.1 3.2 3 0 0 3 3 3 0 Probable zinc-binding domain OrfB_Zn_ribbon PF07282.6 EPS31978.1 - 1.1 8.9 7.3 0.34 10.5 0.2 2.5 2 1 0 2 2 2 0 Putative transposase DNA-binding domain A2L_zn_ribbon PF08792.5 EPS31978.1 - 1.6 8.2 6.4 34 4.0 0.1 3.4 3 0 0 3 3 3 0 A2L zinc ribbon domain Rubredoxin PF00301.15 EPS31978.1 - 5.4 6.9 8.2 12 5.8 0.5 3.7 3 1 0 3 3 3 0 Rubredoxin zf-NADH-PPase PF09297.6 EPS31978.1 - 6.7 6.3 7.6 45 3.6 0.4 3.3 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Rpr2 PF04032.11 EPS31978.1 - 7.5 6.5 6.8 0.99 9.3 0.1 2.4 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Nipped-B_C PF12830.2 EPS31979.1 - 2.6e-50 170.6 0.9 2.6e-50 170.6 0.6 3.0 3 1 1 4 4 4 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 EPS31979.1 - 2.6e-11 43.2 1.6 2.6e-11 43.2 1.1 3.5 4 0 0 4 4 4 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 EPS31979.1 - 8.2e-05 22.5 1.9 0.77 9.5 0.0 3.9 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EPS31979.1 - 0.0046 16.9 4.5 0.97 9.6 0.1 4.9 4 0 0 4 4 4 1 HEAT repeat Adaptin_N PF01602.15 EPS31979.1 - 0.025 12.9 4.6 0.02 13.2 0.5 2.7 3 1 0 3 3 3 0 Adaptin N terminal region Pyr_redox_2 PF07992.9 EPS31980.1 - 3.5e-17 62.9 0.0 7.2e-17 61.9 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPS31980.1 - 6.4e-13 48.9 0.0 1.8e-11 44.2 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 EPS31980.1 - 7e-06 24.9 0.0 4.4e-05 22.4 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 EPS31980.1 - 5.5e-05 23.2 0.1 0.00016 21.7 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 EPS31980.1 - 0.00011 21.3 0.3 0.00047 19.3 0.1 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 EPS31980.1 - 0.00012 21.6 0.2 0.00045 19.8 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain Cna_B PF05738.8 EPS31980.1 - 0.11 12.3 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 Cna protein B-type domain CLTH PF10607.4 EPS31981.1 - 9.2e-33 112.9 0.3 1.2e-32 112.6 0.2 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EPS31981.1 - 1.1e-08 34.5 0.0 1.9e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 LisH DUF1697 PF08002.6 EPS31981.1 - 0.078 13.0 0.0 10 6.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1697) PRK PF00485.13 EPS31982.1 - 2.1e-57 193.8 0.0 3.1e-57 193.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 EPS31982.1 - 7.8e-41 139.5 0.0 1.7e-40 138.4 0.0 1.5 2 0 0 2 2 2 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 EPS31982.1 - 4.1e-08 34.0 0.0 1e-07 32.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPS31982.1 - 4.9e-06 26.8 0.0 1.3e-05 25.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain CPT PF07931.7 EPS31982.1 - 0.00033 20.3 0.0 0.00074 19.1 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.1 EPS31982.1 - 0.011 15.5 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EPS31982.1 - 0.013 14.5 0.0 0.037 13.1 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin APS_kinase PF01583.15 EPS31982.1 - 0.049 13.2 0.3 0.93 9.1 0.0 2.4 3 0 0 3 3 3 0 Adenylylsulphate kinase DUF87 PF01935.12 EPS31982.1 - 0.051 13.4 0.0 0.096 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 NB-ARC PF00931.17 EPS31982.1 - 0.067 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain TIP49 PF06068.8 EPS31982.1 - 0.09 11.4 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus MobB PF03205.9 EPS31982.1 - 0.1 12.3 0.1 0.43 10.2 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 EPS31982.1 - 0.12 12.1 0.0 0.64 9.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Pribosyltran PF00156.22 EPS31982.1 - 0.12 12.1 0.0 1.3 8.8 0.0 2.2 2 0 0 2 2 2 0 Phosphoribosyl transferase domain AAA_22 PF13401.1 EPS31982.1 - 0.15 12.2 0.0 0.56 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain NUC153 PF08159.7 EPS31983.1 - 7e-13 47.9 11.8 9.1e-13 47.5 0.4 3.6 3 0 0 3 3 3 3 NUC153 domain FNIP_N PF14636.1 EPS31984.1 - 4.3e-16 59.5 0.4 4.3e-16 59.5 0.3 4.0 3 2 0 3 3 3 1 Folliculin-interacting protein N-terminus FNIP_M PF14637.1 EPS31984.1 - 0.0051 16.4 0.0 0.019 14.5 0.0 1.8 1 1 1 2 2 2 1 Folliculin-interacting protein middle domain Glyco_hydro_31 PF01055.21 EPS31985.1 - 3.7e-122 408.3 1.1 4.6e-122 408.0 0.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EPS31985.1 - 4.7e-22 77.6 0.1 1.2e-20 73.1 0.2 2.7 2 0 0 2 2 2 1 Galactose mutarotase-like OpcA PF07239.6 EPS31985.1 - 0.052 12.4 0.1 3.1 6.6 0.0 2.2 2 0 0 2 2 2 0 Outer membrane protein OpcA DUF3608 PF12257.3 EPS31986.1 - 3.2e-76 255.9 0.0 5.3e-76 255.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 EPS31986.1 - 6.4e-30 102.7 1.1 1.3e-29 101.7 0.8 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Fungal_trans PF04082.13 EPS31988.1 - 1.6e-18 66.5 0.0 2.9e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS31988.1 - 3.4e-07 30.0 13.6 6.4e-07 29.1 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EPS31989.1 - 2e-22 79.3 0.7 3.4e-22 78.5 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS31989.1 - 0.00033 20.4 6.1 0.00063 19.5 4.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EPS31990.1 - 1.8e-38 132.1 29.8 1.8e-38 132.1 20.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 EPS31991.1 - 7.6e-23 80.7 33.4 7.6e-23 80.7 23.2 2.1 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS31991.1 - 0.00011 20.8 9.3 0.00011 20.8 6.5 3.3 3 1 0 3 3 3 1 Sugar (and other) transporter Glyco_hydro_72 PF03198.9 EPS31992.1 - 2.1e-128 427.7 6.8 2.9e-128 427.2 4.7 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EPS31992.1 - 5.9e-21 74.7 0.6 1.8e-20 73.2 0.4 1.9 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.13 EPS31992.1 - 0.0015 17.7 0.3 0.0055 15.9 0.2 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 EPS31992.1 - 0.0072 15.2 0.1 0.012 14.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cro PF09048.5 EPS31992.1 - 0.08 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Cro Phage_fiber PF03335.8 EPS31994.1 - 1.3 8.9 3.9 5.5 7.0 0.3 2.5 2 0 0 2 2 2 0 Phage tail fibre repeat Na_Ca_ex PF01699.19 EPS31995.1 - 1.8e-47 160.4 31.9 2.7e-24 85.3 9.0 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein TauD PF02668.11 EPS31996.1 - 8.1e-27 94.5 0.0 1e-26 94.1 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family GATase PF00117.23 EPS31997.1 - 0.17 11.3 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase class-I 3HCDH_N PF02737.13 EPS32000.1 - 1.2e-31 109.7 0.0 9.5e-30 103.5 0.0 2.2 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EPS32000.1 - 2.5e-12 47.0 0.0 4.7e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain SGL PF08450.7 EPS32000.1 - 0.0025 17.2 0.2 4.1 6.7 0.0 3.7 1 1 1 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 EPS32000.1 - 0.0069 16.2 0.0 0.53 10.3 0.0 3.4 2 0 0 2 2 2 1 NHL repeat NAD_Gly3P_dh_N PF01210.18 EPS32000.1 - 0.014 15.0 0.0 0.042 13.5 0.0 1.7 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Ldl_recept_b PF00058.12 EPS32000.1 - 0.044 14.1 0.4 15 5.9 0.0 3.9 4 0 0 4 4 4 0 Low-density lipoprotein receptor repeat class B NAD_binding_2 PF03446.10 EPS32000.1 - 0.11 12.3 0.0 0.51 10.1 0.0 2.1 3 0 0 3 3 3 0 NAD binding domain of 6-phosphogluconate dehydrogenase CheX PF13690.1 EPS32000.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Chemotaxis phosphatase CheX Fungal_trans PF04082.13 EPS32003.1 - 5.3e-21 74.6 0.0 8.7e-21 73.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS32003.1 - 7.1e-05 22.6 7.8 0.00013 21.7 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cullin PF00888.17 EPS32004.1 - 5.7e-48 163.8 0.0 1.5e-47 162.4 0.0 1.6 2 0 0 2 2 2 1 Cullin family APC2 PF08672.6 EPS32004.1 - 1e-22 80.1 0.0 2.8e-22 78.7 0.0 1.8 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 FeoC PF09012.5 EPS32004.1 - 0.14 11.8 0.0 5.5 6.7 0.0 2.5 2 0 0 2 2 2 0 FeoC like transcriptional regulator SpdB PF05122.8 EPS32005.1 - 0.0027 17.7 0.0 0.0044 17.0 0.0 1.4 1 0 0 1 1 1 1 Mobile element transfer protein Pkr1 PF08636.5 EPS32006.1 - 2.8e-31 107.3 5.4 4e-31 106.9 3.8 1.2 1 0 0 1 1 1 1 ER protein Pkr1 OAD_gamma PF04277.8 EPS32006.1 - 0.0076 16.6 1.4 0.015 15.6 1.0 1.7 1 1 0 1 1 1 1 Oxaloacetate decarboxylase, gamma chain FHIPEP PF00771.15 EPS32006.1 - 0.11 10.7 0.3 0.13 10.5 0.2 1.1 1 0 0 1 1 1 0 FHIPEP family F-box-like_2 PF13013.1 EPS32007.1 - 0.00049 19.7 0.1 0.0013 18.4 0.1 1.6 1 0 0 1 1 1 1 F-box-like domain F-box-like PF12937.2 EPS32007.1 - 0.0014 18.3 1.4 0.0025 17.5 0.2 2.1 2 0 0 2 2 2 1 F-box-like KKLCAg1 PF15204.1 EPS32007.1 - 0.15 12.0 0.0 0.44 10.6 0.0 1.7 1 0 0 1 1 1 0 Kita-kyushu lung cancer antigen 1 Glyco_hydro_15 PF00723.16 EPS32008.1 - 4.7e-51 173.7 0.0 6.6e-49 166.6 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 TPT PF03151.11 EPS32009.1 - 1.7e-30 105.7 11.3 1.7e-30 105.7 7.8 2.5 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EPS32009.1 - 0.0001 22.3 31.0 0.027 14.4 6.9 2.9 2 2 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 EPS32009.1 - 0.00069 18.6 24.6 0.0024 16.8 17.1 1.7 1 1 0 1 1 1 1 UAA transporter family REV PF00424.13 EPS32009.1 - 0.048 13.5 2.4 0.1 12.4 1.7 1.5 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) DUF4366 PF14283.1 EPS32009.1 - 0.083 12.3 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) AP_endonuc_2 PF01261.19 EPS32010.1 - 3.5e-27 95.0 0.0 6e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Mad3_BUB1_I PF08311.7 EPS32011.1 - 1.1e-44 151.2 0.1 6.4e-43 145.5 0.0 2.4 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 EPS32011.1 - 3.6e-14 52.5 0.0 1.1e-13 50.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS32011.1 - 0.0038 16.3 0.1 0.013 14.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase p450 PF00067.17 EPS32013.1 - 3.7e-40 137.8 0.0 4.9e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_C15 PF01470.12 EPS32015.1 - 5.6e-11 42.6 0.0 8.1e-05 22.5 0.0 2.8 2 1 0 2 2 2 2 Pyroglutamyl peptidase MOSC_N PF03476.11 EPS32016.1 - 9.5e-24 83.4 0.0 1e-22 80.1 0.0 2.1 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EPS32016.1 - 4.5e-16 58.5 0.1 2e-11 43.4 0.0 2.7 3 0 0 3 3 3 2 MOSC domain DNA_pol_phi PF04931.8 EPS32017.1 - 4.4e-67 226.5 27.5 2.8e-66 223.8 19.1 2.3 1 1 0 1 1 1 1 DNA polymerase phi Rad4 PF03835.10 EPS32017.1 - 0.0086 15.4 0.3 0.046 13.1 0.0 2.3 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain Phage_attach PF05354.6 EPS32022.1 - 0.11 11.9 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Phage Head-Tail Attachment VHP PF02209.14 EPS32022.1 - 8.1 6.2 7.0 13 5.5 4.8 1.3 1 0 0 1 1 1 0 Villin headpiece domain Rhodanese PF00581.15 EPS32023.1 - 1.7e-13 50.9 0.0 3.3e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Corona_S2 PF01601.11 EPS32025.1 - 0.022 12.9 11.2 0.03 12.4 7.8 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein FAM163 PF15069.1 EPS32025.1 - 7.7 7.0 15.9 0.24 11.9 5.7 2.3 2 1 1 3 3 3 0 FAM163 family CwfJ_C_1 PF04677.10 EPS32026.1 - 2.4e-24 85.3 0.0 4.2e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EPS32026.1 - 4.8e-23 81.4 0.1 1.1e-22 80.3 0.0 1.6 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 DRIM PF07539.7 EPS32027.1 - 2.6e-48 162.9 0.0 1.3e-47 160.7 0.0 2.3 2 0 0 2 2 2 1 Down-regulated in metastasis HEAT PF02985.17 EPS32027.1 - 0.00014 21.5 5.7 0.23 11.6 0.0 7.8 9 0 0 9 9 9 1 HEAT repeat Methyltransf_23 PF13489.1 EPS32028.1 - 5.2e-10 39.2 0.0 8.1e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPS32028.1 - 6.1e-10 38.8 0.0 9.7e-10 38.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPS32028.1 - 1e-07 32.3 0.0 1.9e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS32028.1 - 2e-07 31.5 0.0 3.6e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPS32028.1 - 3.6e-05 24.1 0.0 6.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPS32028.1 - 0.00016 22.0 0.0 0.00031 21.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPS32028.1 - 0.0071 15.4 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.6 EPS32028.1 - 0.0088 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_4 PF02390.12 EPS32028.1 - 0.033 13.2 0.0 0.12 11.4 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase DJ-1_PfpI_N PF13587.1 EPS32028.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of DJ-1_PfpI family zf-DNL PF05180.7 EPS32029.1 - 1.3e-29 101.6 0.3 2.1e-29 101.0 0.2 1.3 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.8 EPS32029.1 - 4.3e-05 22.9 0.4 7.6e-05 22.1 0.3 1.3 1 0 0 1 1 1 1 CSL zinc finger Elf1 PF05129.8 EPS32029.1 - 0.0011 18.5 1.1 0.0019 17.8 0.8 1.3 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like DUF2039 PF10217.4 EPS32029.1 - 0.01 15.8 0.4 0.015 15.2 0.3 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2039) zf-DNA_Pol PF08996.5 EPS32029.1 - 0.047 13.0 0.6 0.075 12.3 0.4 1.3 1 0 0 1 1 1 0 DNA Polymerase alpha zinc finger TFIIS_C PF01096.13 EPS32029.1 - 0.084 12.5 2.6 6.5 6.4 0.2 2.3 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) E7 PF00527.13 EPS32029.1 - 0.12 12.5 6.3 0.8 9.8 4.4 2.1 1 1 0 1 1 1 0 E7 protein, Early protein Zn_Tnp_IS1595 PF12760.2 EPS32029.1 - 8.7 6.2 6.4 70 3.3 0.5 2.2 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Cullin PF00888.17 EPS32030.1 - 5.1e-130 434.7 8.4 7.7e-130 434.1 5.8 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EPS32030.1 - 2.3e-27 94.5 2.3 6.2e-27 93.2 0.9 2.4 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF3452 PF11934.3 EPS32030.1 - 0.051 12.8 0.3 0.62 9.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3452) Sld5 PF05916.6 EPS32031.1 - 4.8e-11 42.8 0.3 7.2e-11 42.3 0.2 1.2 1 0 0 1 1 1 1 GINS complex protein RCR PF12273.3 EPS32032.1 - 3.5e-29 101.9 8.2 4.2e-29 101.7 5.7 1.1 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Hum_adeno_E3A PF05393.6 EPS32032.1 - 0.016 14.8 0.1 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein KASH PF10541.4 EPS32032.1 - 0.11 12.3 0.1 0.33 10.8 0.1 1.8 1 0 0 1 1 1 0 Nuclear envelope localisation domain Arf PF00025.16 EPS32033.1 - 1.8e-43 147.8 0.0 2.1e-43 147.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EPS32033.1 - 5.1e-19 68.2 0.0 5.8e-19 68.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPS32033.1 - 7.3e-10 39.3 0.0 1.2e-09 38.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EPS32033.1 - 7.4e-07 29.1 0.0 1.2e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EPS32033.1 - 8.1e-07 28.4 0.0 9.7e-07 28.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EPS32033.1 - 3.8e-06 26.2 0.0 4.5e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EPS32033.1 - 5.2e-05 22.7 0.0 0.00051 19.5 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 EPS32033.1 - 6.5e-05 21.7 0.1 0.00025 19.8 0.0 1.9 2 1 1 3 3 3 1 G-protein alpha subunit Dynamin_N PF00350.18 EPS32033.1 - 0.00082 19.2 0.0 0.016 15.0 0.1 2.1 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.13 EPS32033.1 - 0.007 15.6 0.2 0.11 11.7 0.0 2.2 2 1 0 2 2 2 1 Ferrous iron transport protein B RNA_pol_Rpb2_6 PF00562.23 EPS32035.1 - 4.9e-117 390.9 0.1 6.6e-117 390.5 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EPS32035.1 - 3.7e-32 110.9 0.0 5.4e-32 110.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 EPS32035.1 - 7.3e-24 83.3 0.0 1.7e-23 82.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 EPS32035.1 - 7.7e-24 83.4 0.0 1.5e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.9 EPS32035.1 - 2.2e-23 82.6 0.0 3.9e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EPS32035.1 - 5.9e-15 55.3 0.0 3.9e-14 52.6 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 PAT1 PF09770.4 EPS32036.1 - 1.3 7.2 44.0 1.7 6.7 30.5 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 APH PF01636.18 EPS32037.1 - 8e-09 35.5 0.4 2.2e-08 34.1 0.1 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Proteasome PF00227.21 EPS32038.1 - 2.7e-43 147.4 0.6 5.9e-34 117.0 0.1 2.0 2 0 0 2 2 2 2 Proteasome subunit Pil1 PF13805.1 EPS32039.1 - 8.3e-90 300.6 4.9 1e-89 300.2 3.4 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 UPF0231 PF06062.6 EPS32039.1 - 0.024 14.5 0.3 0.45 10.4 0.4 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0231) Spectrin PF00435.16 EPS32039.1 - 0.3 11.4 3.2 1.1 9.5 1.2 2.4 1 1 2 3 3 3 0 Spectrin repeat FlgN PF05130.7 EPS32039.1 - 0.79 9.9 8.4 0.14 12.3 2.1 2.4 2 1 1 3 3 3 0 FlgN protein SWI-SNF_Ssr4 PF08549.5 EPS32040.1 - 8.8e-275 913.2 26.0 8e-274 910.0 18.0 1.9 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1750) Fungal_trans PF04082.13 EPS32042.1 - 1.4e-28 99.4 0.0 2.1e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS32042.1 - 1.3e-07 31.3 7.2 2.3e-07 30.5 5.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EPS32043.1 - 1.7e-27 96.0 52.6 1.7e-27 96.0 36.5 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_N PF08240.7 EPS32044.1 - 5.2e-08 32.6 0.0 1.3e-06 28.1 0.0 2.7 2 2 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPS32044.1 - 2.6e-05 23.7 0.0 4.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPS32044.1 - 0.0056 17.5 0.0 0.011 16.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CMD PF02627.15 EPS32045.1 - 0.06 13.1 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Carboxymuconolactone decarboxylase family AMP-binding PF00501.23 EPS32046.1 - 1.1e-174 580.7 0.2 9.2e-98 327.3 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EPS32046.1 - 2.9e-83 279.1 0.1 5.9e-36 123.8 0.0 3.3 3 0 0 3 3 3 3 Condensation domain AMP-binding_C PF13193.1 EPS32046.1 - 2.3e-17 63.6 0.1 1.3e-08 35.6 0.0 3.1 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain PP-binding PF00550.20 EPS32046.1 - 5.8e-17 61.7 0.3 6.4e-07 29.5 0.1 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site MFS_1 PF07690.11 EPS32047.1 - 1.9e-34 118.9 26.2 1.9e-34 118.9 18.1 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily FUSC_2 PF13515.1 EPS32048.1 - 8.4e-24 83.9 8.4 8.4e-24 83.9 5.8 3.1 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 EPS32048.1 - 2.5e-06 26.4 13.3 0.00028 19.6 1.5 3.7 3 1 0 3 3 3 3 Aluminium activated malate transporter FUSC PF04632.7 EPS32048.1 - 1.4e-05 23.8 21.2 6e-05 21.6 4.7 4.0 2 2 1 3 3 3 2 Fusaric acid resistance protein family DUF2421 PF10334.4 EPS32048.1 - 3.3e-05 23.6 0.1 0.00012 21.7 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) DUF2422 PF10337.4 EPS32048.1 - 0.0017 17.1 0.2 0.0017 17.1 0.1 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2422) Thi4 PF01946.12 EPS32049.1 - 1.7e-102 341.4 0.0 2e-102 341.1 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EPS32049.1 - 3.9e-09 35.8 0.4 3e-08 32.9 0.2 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPS32049.1 - 1.6e-05 24.7 0.6 6.5e-05 22.8 0.2 2.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EPS32049.1 - 3e-05 23.1 0.3 6.2e-05 22.0 0.2 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EPS32049.1 - 0.00017 20.5 1.3 0.011 14.6 0.4 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.1 EPS32049.1 - 0.00061 19.6 0.2 0.0017 18.1 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EPS32049.1 - 0.0015 18.5 0.1 0.0021 18.1 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPS32049.1 - 0.0038 17.1 0.4 0.0077 16.1 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EPS32049.1 - 0.004 16.2 0.0 0.0059 15.7 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EPS32049.1 - 0.0043 16.1 0.0 0.0078 15.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EPS32049.1 - 0.055 11.9 0.1 0.2 10.0 0.3 1.7 2 0 0 2 2 2 0 HI0933-like protein Exo_endo_phos PF03372.18 EPS32050.1 - 9.8e-18 64.9 0.0 1.4e-17 64.5 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.27 EPS32051.1 - 8.7e-56 183.9 19.9 2.1e-13 49.5 0.2 7.8 7 1 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EPS32051.1 - 9.5e-09 35.2 0.1 0.0029 17.3 0.0 2.9 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EPS32051.1 - 4.2e-07 28.4 0.6 0.095 10.8 0.0 4.9 3 2 1 4 4 4 3 Nucleoporin Nup120/160 PD40 PF07676.7 EPS32051.1 - 0.0018 17.9 0.1 0.28 10.9 0.1 2.8 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat SMRP1 PF15181.1 EPS32051.1 - 0.023 14.1 0.0 0.043 13.2 0.0 1.5 1 0 0 1 1 1 0 Spermatid-specific manchette-related protein 1 Glyco_hydro_cc PF11790.3 EPS32052.1 - 2e-65 220.5 0.4 2.3e-65 220.3 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core NAGidase PF07555.8 EPS32054.1 - 2.1e-103 345.4 0.2 3.3e-103 344.7 0.1 1.3 1 0 0 1 1 1 1 beta-N-acetylglucosaminidase Glyco_hydro_20b PF02838.10 EPS32054.1 - 2.1e-15 57.3 0.2 4.1e-15 56.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_67N PF03648.9 EPS32054.1 - 3.7e-05 23.7 0.1 9e-05 22.4 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus CFEM PF05730.6 EPS32060.1 - 1.5 8.6 10.9 3.3 7.6 7.5 1.7 1 1 0 1 1 1 0 CFEM domain Aminotran_5 PF00266.14 EPS32061.1 - 1e-28 100.1 0.0 1.3e-28 99.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.14 EPS32061.1 - 0.00053 19.8 0.1 0.0021 17.8 0.0 2.0 2 1 0 2 2 2 1 B12 binding domain OspD PF03207.8 EPS32061.1 - 0.05 12.7 0.0 0.098 11.7 0.0 1.5 1 0 0 1 1 1 0 Borrelia outer surface protein D (OspD) KR PF08659.5 EPS32061.1 - 0.059 13.0 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 KR domain DDE_Tnp_1_4 PF13701.1 EPS32061.1 - 0.11 10.6 0.0 0.16 10.1 0.0 1.1 1 0 0 1 1 1 0 Transposase DDE domain group 1 Metallophos_2 PF12850.2 EPS32062.1 - 1.4e-15 57.4 0.0 1.8e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RRM_1 PF00076.17 EPS32063.1 - 1.5e-16 59.7 0.0 2.5e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS32063.1 - 1.6e-14 53.6 0.1 4e-14 52.3 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS32063.1 - 3.1e-06 26.9 0.0 4.9e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) V_ATPase_I PF01496.14 EPS32063.1 - 0.013 13.4 0.2 0.015 13.2 0.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family STAT_alpha PF01017.15 EPS32063.1 - 0.04 13.6 0.5 0.059 13.0 0.4 1.1 1 0 0 1 1 1 0 STAT protein, all-alpha domain DUF904 PF06005.7 EPS32063.1 - 0.041 14.1 4.0 0.041 14.1 2.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF904) BLOC1_2 PF10046.4 EPS32063.1 - 0.063 13.4 1.1 0.099 12.7 0.7 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Nup35_RRM_2 PF14605.1 EPS32063.1 - 0.085 12.6 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Med9 PF07544.8 EPS32063.1 - 0.16 11.7 1.0 0.29 10.9 0.7 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 GAS PF13851.1 EPS32063.1 - 0.17 11.0 2.4 0.22 10.6 1.7 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DivIC PF04977.10 EPS32063.1 - 0.18 11.3 3.6 0.32 10.4 2.5 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF4337 PF14235.1 EPS32063.1 - 0.19 11.5 3.9 0.26 11.1 2.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) IncA PF04156.9 EPS32063.1 - 0.23 11.0 4.8 0.32 10.5 3.3 1.1 1 0 0 1 1 1 0 IncA protein DUF4140 PF13600.1 EPS32063.1 - 0.49 10.8 3.7 0.99 9.8 2.6 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) bZIP_2 PF07716.10 EPS32063.1 - 2.9 7.7 7.4 0.52 10.1 2.7 1.6 2 0 0 2 2 2 0 Basic region leucine zipper HECT PF00632.20 EPS32065.1 - 1.7e-93 313.2 0.0 2.3e-93 312.8 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EPS32065.1 - 1.1e-31 108.2 23.4 2.5e-11 43.2 2.1 4.5 4 0 0 4 4 4 3 WW domain C2 PF00168.25 EPS32065.1 - 1.2e-15 57.0 0.0 2.7e-15 55.9 0.0 1.6 1 0 0 1 1 1 1 C2 domain IBR PF01485.16 EPS32066.1 - 7.2e-09 35.3 23.5 1.5e-05 24.7 1.6 4.8 4 1 0 4 4 4 3 IBR domain zf-C3HC4 PF00097.20 EPS32066.1 - 0.0023 17.5 10.8 0.0023 17.5 7.5 4.3 4 1 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPS32066.1 - 0.018 14.8 10.6 0.018 14.8 7.4 4.6 3 1 1 4 4 4 0 Ring finger domain zf-C3HC4_2 PF13923.1 EPS32066.1 - 0.67 10.0 57.0 0.079 12.9 9.4 4.5 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) HD PF01966.17 EPS32067.1 - 0.00013 21.9 0.2 0.0002 21.3 0.1 1.4 1 0 0 1 1 1 1 HD domain Response_reg PF00072.19 EPS32068.1 - 5.9e-22 77.7 0.1 1.5e-21 76.5 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 EPS32068.1 - 3.2e-19 68.6 0.0 6.8e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EPS32068.1 - 5.9e-12 45.4 0.1 2.3e-11 43.5 0.0 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Zn_clus PF00172.13 EPS32070.1 - 1.3e-08 34.6 9.4 2.5e-08 33.6 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EPS32070.1 - 1.8e-08 33.3 0.9 4.9e-08 31.9 0.6 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF241 PF03087.9 EPS32071.1 - 0.012 15.1 2.6 0.012 15.1 1.8 1.7 2 0 0 2 2 2 0 Arabidopsis protein of unknown function Macoilin PF09726.4 EPS32071.1 - 0.026 12.8 7.6 0.031 12.5 5.3 1.1 1 0 0 1 1 1 0 Transmembrane protein V_ATPase_I PF01496.14 EPS32071.1 - 0.04 11.7 6.3 0.051 11.4 4.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2317 PF10079.4 EPS32071.1 - 0.055 12.0 7.4 0.078 11.5 5.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) MbeD_MobD PF04899.7 EPS32071.1 - 0.081 12.8 2.2 11 5.9 0.1 2.8 3 0 0 3 3 2 0 MbeD/MobD like APG6 PF04111.7 EPS32071.1 - 0.089 11.8 15.6 0.15 11.0 10.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.8 EPS32071.1 - 0.093 11.1 8.9 0.15 10.4 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Syntaxin PF00804.20 EPS32071.1 - 0.094 12.8 8.1 0.07 13.2 4.2 1.9 1 1 0 1 1 1 0 Syntaxin Laminin_II PF06009.7 EPS32071.1 - 0.1 12.3 4.3 0.19 11.4 3.0 1.4 1 0 0 1 1 1 0 Laminin Domain II Thiolase_C PF02803.13 EPS32071.1 - 0.14 11.6 0.3 0.26 10.7 0.2 1.5 1 1 0 1 1 1 0 Thiolase, C-terminal domain DUF724 PF05266.9 EPS32071.1 - 0.14 11.8 14.8 0.24 11.0 10.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF485 PF04341.7 EPS32071.1 - 0.15 11.7 0.5 0.81 9.4 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF485 Mnd1 PF03962.10 EPS32071.1 - 0.39 10.3 15.1 0.65 9.6 10.5 1.3 1 0 0 1 1 1 0 Mnd1 family Syntaxin-6_N PF09177.6 EPS32071.1 - 0.5 10.7 10.0 0.36 11.2 4.8 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal OmpH PF03938.9 EPS32071.1 - 1 9.2 16.0 1.8 8.4 11.1 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TMPIT PF07851.8 EPS32071.1 - 1.2 8.1 8.0 1.7 7.6 5.6 1.3 1 0 0 1 1 1 0 TMPIT-like protein DUF87 PF01935.12 EPS32071.1 - 1.5 8.5 4.6 2.2 8.0 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF87 DUF1664 PF07889.7 EPS32071.1 - 2 8.2 9.1 0.87 9.4 3.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ADIP PF11559.3 EPS32071.1 - 2.2 8.2 21.8 3.6 7.4 15.1 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding LMBR1 PF04791.11 EPS32071.1 - 2.6 6.5 5.4 3.6 6.0 3.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF972 PF06156.8 EPS32071.1 - 3.3 8.0 12.1 7.3 6.9 7.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF972) IncA PF04156.9 EPS32071.1 - 4.6 6.7 17.0 1.7 8.1 9.8 1.7 2 0 0 2 2 2 0 IncA protein Nup88 PF10168.4 EPS32071.1 - 6.4 4.4 13.6 8.7 4.0 9.4 1.1 1 0 0 1 1 1 0 Nuclear pore component Atg14 PF10186.4 EPS32071.1 - 6.5 5.5 19.0 10 4.9 13.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 SUR7 PF06687.7 EPS32073.1 - 3.9e-46 157.2 8.9 4.8e-46 156.9 6.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF3099 PF11298.3 EPS32073.1 - 0.035 13.8 0.3 0.035 13.8 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3099) Fig1 PF12351.3 EPS32073.1 - 0.28 11.0 13.8 0.031 14.1 5.8 2.1 2 1 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Claudin_2 PF13903.1 EPS32073.1 - 3.7 7.2 14.4 9.9 5.8 8.8 2.5 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Lactamase_B_2 PF12706.2 EPS32076.1 - 4.6e-20 71.9 0.2 8.1e-20 71.1 0.1 1.4 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EPS32076.1 - 3.3e-15 56.1 0.7 5.4e-15 55.4 0.5 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EPS32076.1 - 0.019 14.6 4.9 0.39 10.3 1.8 2.7 2 1 1 3 3 3 0 Metallo-beta-lactamase superfamily DUF3898 PF13037.1 EPS32076.1 - 0.1 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3898) Tctex-1 PF03645.8 EPS32077.1 - 3.3e-33 113.5 0.0 3.9e-33 113.3 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family NLE PF08154.7 EPS32077.1 - 0.057 13.4 0.0 0.094 12.7 0.0 1.3 1 0 0 1 1 1 0 NLE (NUC135) domain WD40 PF00400.27 EPS32078.1 - 5.4e-48 159.2 18.3 1e-11 44.1 0.1 7.5 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 EPS32078.1 - 8.4e-08 30.8 1.9 0.026 12.6 0.0 4.6 4 1 1 5 5 5 3 Nucleoporin Nup120/160 eIF2A PF08662.6 EPS32078.1 - 0.0005 19.8 0.3 0.019 14.6 0.0 2.9 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EPS32078.1 - 0.024 13.4 0.0 0.59 8.8 0.0 3.1 2 1 0 2 2 2 0 Nup133 N terminal like Coatomer_WDAD PF04053.9 EPS32078.1 - 0.038 12.7 0.0 0.061 12.1 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region Hira PF07569.6 EPS32078.1 - 0.047 12.8 0.3 11 5.1 0.0 3.4 3 1 0 3 3 3 0 TUP1-like enhancer of split IncA PF04156.9 EPS32079.1 - 0.0014 18.2 0.6 0.0027 17.3 0.4 1.4 1 0 0 1 1 1 1 IncA protein CENP-F_leu_zip PF10473.4 EPS32079.1 - 0.023 14.5 3.0 0.56 10.0 0.3 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BRE1 PF08647.6 EPS32079.1 - 0.077 12.9 0.4 0.19 11.7 0.2 1.6 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase FlaC_arch PF05377.6 EPS32079.1 - 0.12 12.3 0.4 0.45 10.4 0.1 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) PEP-utilisers_N PF05524.8 EPS32079.1 - 0.12 12.1 1.6 0.19 11.5 0.6 1.7 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal Swi5 PF07061.6 EPS32079.1 - 0.16 11.7 0.1 0.37 10.5 0.1 1.5 1 0 0 1 1 1 0 Swi5 DUF4047 PF13256.1 EPS32079.1 - 0.24 11.3 3.2 9.5 6.1 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) THOC7 PF05615.8 EPS32079.1 - 0.26 11.5 4.7 3.5 7.8 0.1 2.5 2 0 0 2 2 2 0 Tho complex subunit 7 GAS PF13851.1 EPS32079.1 - 0.35 10.0 6.9 0.9 8.6 4.8 1.6 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Filament PF00038.16 EPS32079.1 - 0.57 9.6 7.2 0.58 9.5 1.4 2.1 1 1 1 2 2 2 0 Intermediate filament protein FadA PF09403.5 EPS32079.1 - 0.91 9.5 4.3 0.9 9.5 1.1 2.2 1 1 1 2 2 2 0 Adhesion protein FadA DUF4337 PF14235.1 EPS32079.1 - 0.94 9.2 3.6 1.6 8.5 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) APG6 PF04111.7 EPS32079.1 - 1.2 8.1 5.6 0.51 9.3 2.2 1.5 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF4201 PF13870.1 EPS32079.1 - 2.8 7.3 10.1 4.5 6.6 0.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DivIC PF04977.10 EPS32079.1 - 6 6.4 4.9 1.6 8.2 0.5 2.0 1 1 1 2 2 2 0 Septum formation initiator Acetyltransf_1 PF00583.19 EPS32080.1 - 4.3e-14 52.2 0.1 7e-14 51.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EPS32080.1 - 8.1e-08 31.9 0.1 1.4e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EPS32080.1 - 0.0024 17.9 0.0 0.0034 17.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EPS32080.1 - 0.01 15.7 0.4 0.015 15.1 0.3 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EPS32080.1 - 0.033 14.3 0.0 0.056 13.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4646 PF15496.1 EPS32081.1 - 0.00048 20.1 1.8 0.0019 18.2 0.3 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4646) adh_short PF00106.20 EPS32083.1 - 7.8e-12 45.4 0.0 3.2e-11 43.4 0.0 1.8 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 EPS32083.1 - 0.00016 21.4 0.0 0.00022 20.9 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EPS32083.1 - 0.0033 17.2 0.0 0.0047 16.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Grp1_Fun34_YaaH PF01184.14 EPS32084.1 - 2.1e-13 50.0 24.1 2e-09 37.0 16.7 3.1 1 1 0 1 1 1 1 GPR1/FUN34/yaaH family Mod_r PF07200.8 EPS32085.1 - 2.5e-11 43.7 5.0 4.3e-11 42.9 3.4 1.3 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Shugoshin_N PF07558.6 EPS32085.1 - 0.0061 16.2 1.0 0.011 15.3 0.7 1.4 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region Ank_5 PF13857.1 EPS32087.1 - 4.5e-12 45.8 0.6 2.8e-11 43.2 0.2 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EPS32087.1 - 2.9e-08 34.0 0.1 1.4e-07 31.8 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPS32087.1 - 1.3e-05 25.0 0.5 0.00036 20.4 0.2 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.2 EPS32087.1 - 1.4e-05 25.3 0.2 3.7e-05 23.9 0.2 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EPS32087.1 - 2.3e-05 23.9 0.1 0.00032 20.3 0.1 2.7 3 0 0 3 3 3 1 Ankyrin repeat YejG PF13989.1 EPS32087.1 - 0.01 15.8 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 0 YejG-like protein tRNA_lig_CPD PF08302.6 EPS32088.1 - 1.5e-89 299.6 0.0 2.4e-89 298.9 0.0 1.3 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.5 EPS32088.1 - 4.9e-82 274.6 0.2 8e-82 273.9 0.2 1.4 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.6 EPS32088.1 - 1.4e-48 164.9 0.0 2.5e-48 164.1 0.0 1.4 1 0 0 1 1 1 1 tRNA ligase kinase domain Got1 PF04178.7 EPS32089.1 - 3.1e-33 114.3 14.3 4e-33 114.0 9.9 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family Peptidase_M50 PF02163.17 EPS32089.1 - 0.0041 16.1 0.1 0.013 14.4 0.1 1.7 1 1 0 1 1 1 1 Peptidase family M50 DUF3780 PF12635.2 EPS32090.1 - 0.026 14.0 0.5 0.034 13.6 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3780) HLH PF00010.21 EPS32094.1 - 2.1e-13 49.7 0.0 9.2e-13 47.6 0.0 2.2 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain APH PF01636.18 EPS32096.1 - 1.1e-17 64.6 0.0 2.5e-17 63.4 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPS32096.1 - 0.0019 17.7 0.0 0.0029 17.2 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase SOG2 PF10428.4 EPS32097.1 - 5.8e-05 21.9 2.5 6.9e-05 21.6 1.8 1.3 1 0 0 1 1 1 1 RAM signalling pathway protein AIP3 PF03915.8 EPS32098.1 - 3.6e-157 523.6 7.2 6e-157 522.9 5.0 1.4 1 0 0 1 1 1 1 Actin interacting protein 3 Lectin_N PF03954.9 EPS32098.1 - 0.00053 19.4 0.4 0.00053 19.4 0.3 2.3 2 0 0 2 2 2 1 Hepatic lectin, N-terminal domain DHC_N2 PF08393.8 EPS32098.1 - 0.0085 14.6 3.4 0.015 13.7 0.5 2.1 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 FliL PF03748.9 EPS32098.1 - 0.087 12.8 0.9 0.34 10.9 0.1 2.5 2 0 0 2 2 2 0 Flagellar basal body-associated protein FliL DUF1381 PF07129.6 EPS32098.1 - 0.13 11.7 0.9 0.3 10.5 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1381) Syntaxin_2 PF14523.1 EPS32098.1 - 0.48 10.4 6.8 1.4 8.9 0.1 4.1 3 1 1 4 4 4 0 Syntaxin-like protein LsmAD PF06741.8 EPS32100.1 - 7.1e-26 90.1 2.5 1.7e-25 88.9 1.7 1.7 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.1 EPS32100.1 - 1.2e-16 60.3 0.1 3.3e-16 58.9 0.0 1.8 1 0 0 1 1 1 1 Ataxin 2 SM domain Tmemb_185A PF10269.4 EPS32101.1 - 0.071 12.6 0.0 0.074 12.6 0.0 1.1 1 0 0 1 1 1 0 Transmembrane Fragile-X-F protein HEAT PF02985.17 EPS32102.1 - 5.5e-10 38.4 3.2 0.059 13.4 0.0 5.6 5 1 0 5 5 5 3 HEAT repeat Pkinase PF00069.20 EPS32102.1 - 1e-08 34.6 0.0 1.7e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT_EZ PF13513.1 EPS32102.1 - 1.7e-05 25.1 0.6 0.16 12.5 0.3 3.5 2 0 0 2 2 2 2 HEAT-like repeat Pkinase_Tyr PF07714.12 EPS32102.1 - 1.7e-05 24.0 0.0 3.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.1 EPS32102.1 - 5.3e-05 23.4 0.2 0.23 11.7 0.0 3.5 1 1 2 3 3 3 2 HEAT repeats Kinase-like PF14531.1 EPS32102.1 - 0.0034 16.3 0.0 0.0059 15.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Cnd1 PF12717.2 EPS32102.1 - 0.033 14.0 0.0 0.18 11.6 0.0 2.0 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 EPS32102.1 - 0.052 11.8 0.0 0.1 10.8 0.0 1.4 1 1 0 1 1 1 0 Adaptin N terminal region Ipi1_N PF12333.3 EPS32102.1 - 0.06 13.3 0.0 7.9 6.5 0.0 2.6 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation CoA_trans PF01144.18 EPS32102.1 - 0.09 11.9 0.0 0.2 10.7 0.0 1.5 1 0 0 1 1 1 0 Coenzyme A transferase Aldo_ket_red PF00248.16 EPS32103.1 - 4.9e-53 179.7 0.0 5.7e-53 179.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family VIT1 PF01988.14 EPS32104.1 - 4e-64 215.9 3.1 4.6e-64 215.8 2.1 1.0 1 0 0 1 1 1 1 VIT family DUF1129 PF06570.6 EPS32104.1 - 3.4 6.9 5.1 49 3.1 2.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) NAD_binding_6 PF08030.7 EPS32105.1 - 1.2e-15 57.7 0.0 1.7e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EPS32105.1 - 1.2e-14 54.5 14.9 1.2e-14 54.5 10.3 3.7 3 2 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EPS32105.1 - 1.3e-11 44.3 0.0 3.5e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain PDR_assoc PF08370.6 EPS32105.1 - 0.00063 19.2 1.1 0.016 14.6 0.1 2.6 2 0 0 2 2 2 1 Plant PDR ABC transporter associated GFA PF04828.9 EPS32106.1 - 1.2e-11 44.3 0.6 1.9e-11 43.7 0.4 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme CHCH PF06747.8 EPS32107.1 - 3.7e-06 26.6 0.4 5.2e-06 26.2 0.2 1.2 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 EPS32107.1 - 0.066 13.2 2.0 0.29 11.1 1.5 1.8 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.8 EPS32107.1 - 0.15 12.1 3.5 5.2 7.1 0.2 2.2 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) NPR3 PF03666.8 EPS32108.1 - 5.5e-137 456.9 0.1 1.2e-136 455.8 0.0 1.6 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.6 EPS32108.1 - 0.0096 14.6 0.0 0.074 11.7 0.0 2.2 2 0 0 2 2 2 1 Nitrogen permease regulator 2 HTH_IclR PF09339.5 EPS32108.1 - 0.14 11.7 1.6 1.1 8.9 0.0 3.0 3 0 0 3 3 3 0 IclR helix-turn-helix domain Mago-bind PF09282.5 EPS32108.1 - 6.5 6.4 8.0 0.5 9.9 1.4 2.2 2 0 0 2 2 2 0 Mago binding La PF05383.12 EPS32109.1 - 5.8e-19 67.6 0.0 1e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 La domain RRN9 PF10680.4 EPS32109.1 - 1 9.1 7.8 4.1 7.1 0.0 3.6 3 0 0 3 3 3 0 RNA polymerase I specific transcription initiation factor Band_7 PF01145.20 EPS32110.1 - 1.1e-30 106.8 0.4 1.1e-30 106.8 0.3 1.7 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EPS32110.1 - 0.044 13.2 0.0 0.079 12.4 0.0 1.5 1 1 0 1 1 1 0 SPFH domain-Band 7 family DRTGG PF07085.7 EPS32110.1 - 0.12 12.0 0.6 1.6 8.3 0.0 2.7 3 0 0 3 3 3 0 DRTGG domain Hira PF07569.6 EPS32111.1 - 1.3e-82 276.3 0.0 2.7e-82 275.2 0.0 1.6 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.27 EPS32111.1 - 2.3e-40 135.0 23.6 1.5e-07 30.9 0.0 8.9 8 0 0 8 8 8 7 WD domain, G-beta repeat HIRA_B PF09453.5 EPS32111.1 - 6.1e-10 38.3 0.1 1.7e-09 36.9 0.0 1.8 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 EPS32111.1 - 6.2e-06 25.7 0.7 1.6 8.4 0.0 5.6 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat IKI3 PF04762.7 EPS32111.1 - 0.032 12.0 0.1 0.12 10.2 0.0 1.5 1 1 0 1 1 1 0 IKI3 family YchF-GTPase_C PF06071.8 EPS32112.1 - 1.1e-33 114.8 0.4 2.4e-33 113.7 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EPS32112.1 - 9.4e-13 48.1 0.0 4.9e-12 45.8 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EPS32112.1 - 0.00067 18.9 0.0 0.0013 17.9 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 EPS32112.1 - 0.0013 18.5 0.0 0.0036 17.0 0.0 1.8 2 0 0 2 2 2 1 TGS domain SecA_PP_bind PF01043.15 EPS32112.1 - 0.025 14.9 0.1 0.096 13.0 0.0 1.8 1 1 0 1 1 1 0 SecA preprotein cross-linking domain AAA_14 PF13173.1 EPS32112.1 - 0.027 14.3 0.0 0.067 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EPS32112.1 - 0.072 12.7 0.4 1.8 8.2 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 EPS32112.1 - 0.13 12.0 0.2 2 8.1 0.0 2.4 2 1 1 3 3 3 0 Dynamin family PUA PF01472.15 EPS32113.1 - 1.1e-13 50.7 0.3 1.4e-13 50.3 0.2 1.2 1 0 0 1 1 1 1 PUA domain RIC1 PF07064.8 EPS32114.1 - 4e-86 288.6 0.1 6.1e-86 288.0 0.0 1.3 1 0 0 1 1 1 1 RIC1 TPR_11 PF13414.1 EPS32115.1 - 2.2e-24 84.9 6.4 1.1e-17 63.4 1.1 2.3 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EPS32115.1 - 4.9e-20 70.2 5.0 1.2e-06 27.9 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EPS32115.1 - 1.5e-17 62.0 4.8 4e-06 26.3 0.1 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EPS32115.1 - 7.3e-10 37.9 5.2 0.00055 19.5 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EPS32115.1 - 1.3e-09 38.4 6.5 4e-06 27.3 1.5 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EPS32115.1 - 1.2e-08 34.8 3.5 0.0089 16.5 0.2 3.6 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 EPS32115.1 - 1.6e-08 33.7 0.2 0.036 13.8 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EPS32115.1 - 3.7e-08 32.9 5.8 0.00047 20.1 0.2 3.3 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EPS32115.1 - 2.5e-07 30.5 5.4 0.00016 21.5 0.6 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EPS32115.1 - 6.8e-07 29.5 2.8 9.1e-05 22.7 0.8 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EPS32115.1 - 8.8e-07 28.6 0.9 0.00083 19.1 0.1 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat XPC-binding PF09280.6 EPS32115.1 - 0.0005 19.4 2.7 0.00098 18.5 1.3 1.9 2 0 0 2 2 2 1 XPC-binding domain BTAD PF03704.12 EPS32115.1 - 0.00079 19.7 0.5 0.012 15.9 0.1 2.3 2 0 0 2 2 2 1 Bacterial transcriptional activator domain TPR_6 PF13174.1 EPS32115.1 - 0.0019 18.5 6.2 0.3 11.6 0.2 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EPS32115.1 - 0.0034 17.4 1.0 0.44 10.7 0.0 2.3 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 EPS32115.1 - 0.0084 15.1 0.2 0.013 14.6 0.2 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat MIT PF04212.13 EPS32115.1 - 0.039 13.8 2.8 1.3 8.9 0.3 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 EPS32115.1 - 0.73 9.8 3.8 21 5.1 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1860 PF08949.5 EPS32115.1 - 1.5 8.3 7.7 1.5 8.3 1.2 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1860) Tim44 PF04280.10 EPS32116.1 - 1.7e-32 112.4 0.1 6.1e-32 110.6 0.0 1.9 2 0 0 2 2 2 1 Tim44-like domain KIF1B PF12423.3 EPS32116.1 - 0.026 14.5 0.0 0.072 13.1 0.0 1.8 1 0 0 1 1 1 0 Kinesin protein 1B Sporozoite_P67 PF05642.6 EPS32116.1 - 0.044 11.6 6.1 0.064 11.1 4.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ribosomal_S11 PF00411.14 EPS32117.1 - 5.6e-08 32.9 0.0 8.7e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 VPS9 PF02204.13 EPS32118.1 - 3.3e-17 62.4 0.0 7.8e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.1 EPS32118.1 - 1.5e-15 56.8 0.0 7.1e-11 41.9 0.0 4.8 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EPS32118.1 - 1.7e-11 44.2 0.0 0.00066 19.9 0.0 3.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPS32118.1 - 4e-08 33.5 0.0 0.011 16.2 0.0 4.3 3 1 1 4 4 4 2 Ankyrin repeats (many copies) PX PF00787.19 EPS32118.1 - 4.7e-08 32.8 0.7 1.5e-07 31.2 0.2 2.0 2 0 0 2 2 2 1 PX domain Ank PF00023.25 EPS32118.1 - 6.9e-07 28.7 0.6 0.1 12.4 0.0 4.9 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.1 EPS32118.1 - 2.3e-06 27.2 0.0 12 6.5 0.0 5.9 5 0 0 5 5 5 1 Ankyrin repeat Inhibitor_I78 PF11720.3 EPS32120.1 - 1.2e-11 44.1 0.0 1.4e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 EPS32120.1 - 0.032 14.3 0.3 0.045 13.9 0.2 1.4 1 1 0 1 1 1 0 Potato inhibitor I family Mid2 PF04478.7 EPS32120.1 - 0.15 11.4 0.1 0.17 11.2 0.1 1.1 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Alpha-L-AF_C PF06964.7 EPS32121.1 - 8.6e-36 123.3 0.0 1.3e-35 122.7 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Sugar_tr PF00083.19 EPS32122.1 - 3.6e-101 338.9 24.9 4.1e-101 338.7 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS32122.1 - 9.4e-29 100.2 29.3 1.6e-21 76.4 7.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Lig_chan PF00060.21 EPS32122.1 - 1.3 8.7 4.4 8.1 6.1 0.1 2.6 2 0 0 2 2 2 0 Ligand-gated ion channel Nefa_Nip30_N PF10187.4 EPS32123.1 - 2.9e-30 104.4 15.5 2.9e-30 104.4 10.7 2.1 2 1 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF2075 PF09848.4 EPS32123.1 - 0.028 13.4 1.9 0.038 12.9 1.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Aldo_ket_red PF00248.16 EPS32126.1 - 1.6e-43 148.5 0.0 2e-43 148.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PRCH PF03967.8 EPS32129.1 - 0.045 13.3 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 Photosynthetic reaction centre, H-chain N-terminal region MscS_porin PF12795.2 EPS32133.1 - 0.0017 17.7 4.6 0.0019 17.5 3.2 1.0 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain IncA PF04156.9 EPS32133.1 - 0.0021 17.6 1.4 0.0029 17.2 1.0 1.1 1 0 0 1 1 1 1 IncA protein FlxA PF14282.1 EPS32133.1 - 0.0023 17.8 2.4 0.0029 17.5 1.7 1.1 1 0 0 1 1 1 1 FlxA-like protein DivIC PF04977.10 EPS32133.1 - 0.007 15.8 0.8 0.007 15.8 0.5 1.4 2 0 0 2 2 2 1 Septum formation initiator Prefoldin_2 PF01920.15 EPS32133.1 - 0.013 15.2 0.1 0.015 15.0 0.1 1.1 1 0 0 1 1 1 0 Prefoldin subunit DUF948 PF06103.6 EPS32133.1 - 0.062 13.1 0.1 0.092 12.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF3573 PF12097.3 EPS32133.1 - 0.12 10.9 0.1 0.14 10.7 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) HR1 PF02185.11 EPS32133.1 - 0.15 11.7 1.6 0.19 11.4 1.1 1.2 1 0 0 1 1 1 0 Hr1 repeat Viral_P18 PF04521.8 EPS32133.1 - 0.21 11.0 1.0 0.27 10.6 0.7 1.1 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein T2SM PF04612.7 EPS32133.1 - 0.34 10.7 6.1 1.2 8.9 4.2 1.7 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein M Sugarporin_N PF11471.3 EPS32133.1 - 0.96 9.1 4.2 3.3 7.4 2.9 1.9 1 1 0 1 1 1 0 Maltoporin periplasmic N-terminal extension DUF883 PF05957.8 EPS32134.1 - 0.076 13.4 1.4 2.3 8.6 0.3 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) zf-H2C2_2 PF13465.1 EPS32135.1 - 2.1e-15 56.1 37.8 2.4e-07 30.6 1.3 7.3 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.21 EPS32135.1 - 5.6e-15 54.6 53.8 1.2e-05 25.3 1.3 8.9 9 0 0 9 9 9 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPS32135.1 - 1.1e-09 37.9 52.9 0.00033 20.7 1.6 8.9 9 1 0 9 9 9 4 C2H2-type zinc finger zf-met PF12874.2 EPS32135.1 - 1.4e-09 37.7 15.3 0.0011 19.1 0.2 6.4 6 0 0 6 6 6 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EPS32135.1 - 2.8e-09 36.8 20.4 0.00047 20.2 0.4 6.7 6 0 0 6 6 6 3 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EPS32135.1 - 0.058 13.3 0.5 0.058 13.3 0.4 4.9 5 0 0 5 5 5 0 C2H2-type zinc finger DEAD PF00270.24 EPS32137.1 - 4.3e-45 153.2 0.0 1e-44 151.9 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPS32137.1 - 1.9e-25 88.5 0.0 5.7e-25 86.9 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EPS32137.1 - 0.0015 17.4 0.0 0.0026 16.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EPS32137.1 - 0.015 15.1 0.0 0.093 12.5 0.0 2.4 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit HMG_box PF00505.14 EPS32138.1 - 3.8e-11 43.1 1.2 3.8e-11 43.1 0.8 2.7 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EPS32138.1 - 3.8e-08 33.5 0.4 3.8e-08 33.5 0.3 3.0 3 0 0 3 3 3 1 HMG-box domain HMG_box_5 PF14887.1 EPS32138.1 - 0.004 16.8 0.1 0.004 16.8 0.1 2.6 3 0 0 3 3 3 1 HMG (high mobility group) box 5 Antigen_Bd37 PF11641.3 EPS32138.1 - 0.053 12.8 1.7 0.077 12.2 1.1 1.2 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein Herpes_Helicase PF02689.9 EPS32138.1 - 0.19 9.4 1.3 0.26 8.9 0.9 1.1 1 0 0 1 1 1 0 Helicase MAT1 PF06391.8 EPS32138.1 - 5.3 6.5 12.9 4.1 6.9 7.6 1.8 1 1 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 Mito_carr PF00153.22 EPS32140.1 - 6.4e-45 150.7 0.6 1.8e-17 62.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein JAB PF01398.16 EPS32141.1 - 3.9e-07 29.8 0.1 3.7e-06 26.6 0.1 2.2 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Phage_XkdX PF09693.5 EPS32141.1 - 0.046 13.2 0.1 0.12 11.8 0.1 1.6 1 0 0 1 1 1 0 Phage uncharacterised protein (Phage_XkdX) Abhydrolase_6 PF12697.2 EPS32142.1 - 3.7e-07 30.2 1.9 6.5e-07 29.4 1.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EPS32142.1 - 1.6e-05 24.5 0.0 0.0073 15.8 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPS32142.1 - 1.9e-05 24.4 0.0 6.8e-05 22.6 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF3089 PF11288.3 EPS32142.1 - 0.0034 16.5 0.0 0.0097 15.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3089) DUF2974 PF11187.3 EPS32142.1 - 0.011 15.0 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.15 EPS32142.1 - 0.012 15.1 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF915 PF06028.6 EPS32142.1 - 0.079 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) CK_II_beta PF01214.13 EPS32143.1 - 1e-73 246.7 0.1 1.3e-73 246.4 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Acetyltransf_3 PF13302.1 EPS32144.1 - 1.9e-23 83.1 0.0 2.3e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPS32144.1 - 2.4e-08 33.8 0.0 1.6e-07 31.2 0.0 2.0 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EPS32144.1 - 0.0042 16.9 0.0 0.0052 16.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Transp_cyt_pur PF02133.10 EPS32145.1 - 2.5e-27 95.5 31.2 4.3e-27 94.7 21.7 1.4 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin MreC PF04085.9 EPS32147.1 - 0.088 12.2 0.0 0.098 12.0 0.0 1.1 1 0 0 1 1 1 0 rod shape-determining protein MreC Hemerythrin PF01814.18 EPS32149.1 - 2.4e-16 60.1 0.3 3.1e-16 59.7 0.2 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DDE_3 PF13358.1 EPS32150.1 - 1.9e-31 108.7 0.0 4.5e-31 107.5 0.0 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_1 PF03184.14 EPS32150.1 - 9.4e-08 31.4 0.0 1.3e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EPS32150.1 - 1.4e-07 31.6 0.0 2.7e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain HTH_33 PF13592.1 EPS32150.1 - 0.0014 18.1 0.4 0.0033 16.9 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn helix DDE_Tnp_ISAZ013 PF07592.6 EPS32150.1 - 0.019 13.7 0.0 0.6 8.8 0.0 2.1 2 0 0 2 2 2 0 Rhodopirellula transposase DDE domain NB-ARC PF00931.17 EPS32151.1 - 4.6e-08 32.2 0.0 0.0011 17.9 0.0 2.2 2 0 0 2 2 2 2 NB-ARC domain TPR_10 PF13374.1 EPS32151.1 - 2.1e-07 30.6 0.6 1.2e-05 25.0 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat AAA_22 PF13401.1 EPS32151.1 - 0.00031 20.8 0.0 0.001 19.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EPS32151.1 - 0.00041 20.0 0.0 0.00097 18.8 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EPS32151.1 - 0.002 18.1 0.4 0.054 13.4 0.3 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 EPS32151.1 - 0.016 14.6 0.0 0.03 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain TPR_12 PF13424.1 EPS32151.1 - 0.028 14.3 2.7 0.028 14.3 0.1 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat IstB_IS21 PF01695.12 EPS32151.1 - 0.056 12.8 0.0 0.24 10.8 0.0 2.1 2 1 0 2 2 2 0 IstB-like ATP binding protein AAA_assoc PF14363.1 EPS32153.1 - 0.018 15.1 0.2 0.031 14.3 0.1 1.4 1 0 0 1 1 1 0 Domain associated at C-terminal with AAA AAA_16 PF13191.1 EPS32158.1 - 1.1e-05 25.5 2.3 0.00023 21.2 0.1 3.2 2 2 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 EPS32158.1 - 0.00075 19.1 0.7 0.0026 17.4 0.1 2.3 2 1 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 EPS32158.1 - 0.0064 16.2 0.0 0.032 13.9 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 EPS32158.1 - 0.024 14.8 1.2 0.36 10.9 0.2 3.1 1 1 0 2 2 2 0 AAA domain p450 PF00067.17 EPS32160.1 - 1.3e-38 132.7 0.0 2.2e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EPS32161.1 - 1.7e-36 125.6 32.8 1.7e-36 125.6 22.8 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily RCR PF12273.3 EPS32161.1 - 0.17 12.4 0.0 0.43 11.1 0.0 1.7 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Peptidase_M20 PF01546.23 EPS32162.1 - 1.7e-11 44.0 0.3 2.4e-11 43.5 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EPS32162.1 - 2.7e-09 36.7 0.0 7.2e-09 35.3 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Fungal_trans_2 PF11951.3 EPS32163.1 - 1e-10 40.8 0.7 2.3e-07 29.7 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain GWT1 PF06423.7 EPS32163.1 - 0.086 12.9 0.1 0.21 11.6 0.1 1.6 1 0 0 1 1 1 0 GWT1 Glyco_hydro_6 PF01341.12 EPS32164.1 - 1.3e-113 379.3 0.7 1.7e-113 379.0 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.13 EPS32164.1 - 4.8e-12 45.3 11.2 4.8e-12 45.3 7.8 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain MGC-24 PF05283.6 EPS32164.1 - 0.53 10.0 15.8 1.1 8.9 10.9 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) SpvB PF03534.8 EPS32168.1 - 1.3e-78 263.9 0.1 2.4e-78 263.1 0.1 1.4 1 0 0 1 1 1 1 Salmonella virulence plasmid 65kDa B protein TcdB_toxin_midN PF12256.3 EPS32168.1 - 2.9e-36 124.5 0.2 3e-27 95.1 0.0 5.5 3 1 2 5 5 5 3 Insecticide toxin TcdB middle/N-terminal region TcdB_toxin_midC PF12255.3 EPS32168.1 - 8.5e-27 93.6 1.6 1.7e-26 92.6 0.7 1.8 2 0 0 2 2 2 1 Insecticide toxin TcdB middle/C-terminal region VCBS PF13517.1 EPS32168.1 - 0.00023 21.4 0.1 0.084 13.2 0.0 3.8 3 1 1 4 4 4 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella RHS_repeat PF05593.9 EPS32168.1 - 0.00039 20.4 30.4 0.015 15.4 0.6 8.5 9 0 0 9 9 9 2 RHS Repeat FG-GAP PF01839.18 EPS32168.1 - 0.042 13.5 0.4 1.6 8.4 0.1 2.7 2 0 0 2 2 2 0 FG-GAP repeat Na_Ca_ex PF01699.19 EPS32169.1 - 3.8e-26 91.3 30.8 2.5e-16 59.5 9.3 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein UPF0261 PF06792.6 EPS32170.1 - 5.2e-136 453.2 0.0 3.3e-106 355.1 0.1 2.1 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0261) DUF1294 PF06961.8 EPS32170.1 - 0.19 11.6 0.2 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1294) AdoHcyase PF05221.12 EPS32171.1 - 3.9e-138 458.8 0.1 4.4e-138 458.6 0.1 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EPS32171.1 - 1.9e-82 274.9 2.5 3.2e-82 274.2 1.7 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EPS32171.1 - 1.1e-06 27.9 0.2 3.2e-06 26.3 0.1 1.8 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EPS32171.1 - 0.00098 18.5 0.3 0.0018 17.6 0.2 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain ELFV_dehydrog PF00208.16 EPS32171.1 - 0.0041 16.7 0.2 0.009 15.6 0.2 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.13 EPS32171.1 - 0.0055 16.6 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain adh_short PF00106.20 EPS32171.1 - 0.031 14.2 1.3 6.6 6.6 0.1 2.4 2 0 0 2 2 2 0 short chain dehydrogenase ETRAMP PF09716.5 EPS32172.1 - 0.1 12.5 0.1 0.35 10.8 0.1 1.9 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) zf-C2H2_4 PF13894.1 EPS32174.1 - 4e-08 33.0 9.4 6.3e-06 26.1 1.0 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EPS32174.1 - 2.8e-07 30.4 11.4 7.2e-06 26.0 1.7 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EPS32174.1 - 7.7e-06 25.9 2.3 7.7e-06 25.9 1.6 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.2 EPS32174.1 - 0.00071 19.6 0.5 0.00071 19.6 0.3 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-Di19 PF05605.7 EPS32174.1 - 0.0011 19.0 4.1 0.0019 18.2 2.8 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 EPS32174.1 - 0.0064 16.6 0.9 0.0064 16.6 0.6 1.9 2 0 0 2 2 1 1 Zinc-finger double-stranded RNA-binding DUF2225 PF09986.4 EPS32174.1 - 0.0066 15.9 0.2 0.01 15.3 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2225) DUF1178 PF06676.6 EPS32174.1 - 0.011 15.8 0.7 0.02 15.0 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) PRP21_like_P PF12230.3 EPS32174.1 - 0.017 14.6 1.3 0.031 13.7 0.5 1.4 1 1 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein NOA36 PF06524.7 EPS32174.1 - 0.11 11.7 3.8 0.17 11.0 2.7 1.2 1 0 0 1 1 1 0 NOA36 protein zf-C2H2_2 PF12756.2 EPS32174.1 - 0.18 11.9 1.6 0.28 11.3 1.1 1.3 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 EPS32174.1 - 0.21 11.3 5.8 0.45 10.3 4.0 1.6 1 0 0 1 1 1 0 BED zinc finger TIM-br_sig_trns PF09370.5 EPS32175.1 - 1.3e-133 444.0 0.3 1.5e-133 443.8 0.2 1.0 1 0 0 1 1 1 1 TIM-barrel signal transduction protein NMO PF03060.10 EPS32175.1 - 0.00014 21.1 0.1 0.00022 20.5 0.1 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase PcrB PF01884.12 EPS32175.1 - 0.044 13.0 1.2 4.7 6.3 0.1 2.3 2 0 0 2 2 2 0 PcrB family adh_short PF00106.20 EPS32176.1 - 6.2e-28 97.8 0.0 9.9e-28 97.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPS32176.1 - 3.9e-19 69.3 0.0 1.2e-18 67.7 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPS32176.1 - 2e-12 47.1 0.0 3.3e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPS32176.1 - 0.00011 21.7 0.0 0.0006 19.3 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ring_hydroxyl_A PF00848.14 EPS32179.1 - 8.7e-40 136.5 3.9 1.6e-39 135.6 2.7 1.4 1 0 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) HATPase_c PF02518.21 EPS32180.1 - 2.9e-16 59.1 0.0 5e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EPS32180.1 - 1e-14 54.4 0.0 2.2e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EPS32180.1 - 5.1e-10 39.1 0.0 1.4e-09 37.8 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 EPS32180.1 - 0.00045 19.8 0.0 0.00086 18.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ehrlichia_rpt PF09528.5 EPS32180.1 - 0.15 10.1 0.0 0.21 9.6 0.0 1.1 1 0 0 1 1 1 0 Ehrlichia tandem repeat (Ehrlichia_rpt) Kelch_6 PF13964.1 EPS32181.1 - 0.0021 18.1 9.9 1.2 9.3 0.0 5.5 4 1 1 5 5 5 1 Kelch motif TMEM154 PF15102.1 EPS32181.1 - 0.0052 16.5 0.3 0.014 15.0 0.0 1.8 2 0 0 2 2 2 1 TMEM154 protein family Kelch_3 PF13415.1 EPS32181.1 - 0.0087 16.2 0.2 0.0087 16.2 0.1 4.5 5 1 1 6 6 6 1 Galactose oxidase, central domain Rax2 PF12768.2 EPS32181.1 - 0.0099 15.1 0.2 0.25 10.4 0.1 2.7 2 1 0 2 2 2 1 Cortical protein marker for cell polarity Herpes_gE PF02480.11 EPS32181.1 - 0.036 12.3 0.1 0.058 11.6 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Mid2 PF04478.7 EPS32181.1 - 0.063 12.6 3.4 0.16 11.3 2.3 1.7 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor Kelch_5 PF13854.1 EPS32181.1 - 0.093 12.7 4.5 7.6 6.6 0.0 3.6 4 0 0 4 4 4 0 Kelch motif EphA2_TM PF14575.1 EPS32181.1 - 0.11 12.8 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain HAT PF02184.11 EPS32183.1 - 1.5e-21 75.8 81.6 1.4e-13 50.3 4.2 14.1 15 0 0 15 15 15 5 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 EPS32183.1 - 2.2e-21 74.3 22.4 0.018 15.6 0.1 11.7 7 3 6 13 13 13 5 Tetratricopeptide repeat TPR_19 PF14559.1 EPS32183.1 - 3.3e-20 72.2 0.6 4e-05 23.8 0.0 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 EPS32183.1 - 2.9e-19 69.1 9.7 0.007 17.0 0.0 9.2 9 1 1 10 10 10 4 Tetratricopeptide repeat Suf PF05843.9 EPS32183.1 - 1.4e-16 61.0 22.0 4.6e-05 23.3 0.4 6.2 2 1 3 6 6 6 4 Suppressor of forked protein (Suf) TPR_11 PF13414.1 EPS32183.1 - 3.8e-09 36.0 4.6 0.38 10.4 0.0 6.5 6 2 0 6 6 6 3 TPR repeat TPR_17 PF13431.1 EPS32183.1 - 9.1e-07 28.6 7.6 0.12 12.6 0.1 6.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 EPS32183.1 - 6.7e-06 25.9 18.9 0.25 11.3 0.0 8.4 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_15 PF13429.1 EPS32183.1 - 1.5e-05 24.2 16.1 0.11 11.5 0.5 5.7 2 2 2 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 EPS32183.1 - 1.6e-05 24.4 23.4 2.7 8.1 0.0 9.2 10 0 0 10 10 10 1 Tetratricopeptide repeat U3_assoc_6 PF08640.6 EPS32183.1 - 4.7e-05 23.0 28.1 0.038 13.7 1.3 7.1 5 2 2 7 7 7 2 U3 small nucleolar RNA-associated protein 6 TPR_8 PF13181.1 EPS32183.1 - 5.4e-05 22.6 6.9 4.9 7.1 0.0 6.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EPS32183.1 - 0.0027 17.4 18.9 14 5.7 0.1 7.4 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 EPS32183.1 - 0.0081 15.7 4.7 20 4.9 0.1 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 EPS32183.1 - 0.038 14.4 23.0 9.5 6.9 0.0 8.5 9 0 0 9 9 9 0 Tetratricopeptide repeat Prp31_C PF09785.4 EPS32184.1 - 5.7e-46 155.9 0.3 1.1e-45 155.0 0.2 1.5 1 0 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.13 EPS32184.1 - 4.4e-37 126.6 0.1 7.5e-37 125.9 0.1 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EPS32184.1 - 3.7e-15 55.4 0.1 7.2e-15 54.5 0.1 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain PhyH PF05721.8 EPS32186.1 - 2.1e-08 34.4 0.0 4.2e-08 33.4 0.0 1.5 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF2379 PF09543.5 EPS32186.1 - 0.054 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) Aldo_ket_red PF00248.16 EPS32188.1 - 5.1e-60 202.7 0.0 5.7e-60 202.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-H2C2_2 PF13465.1 EPS32189.1 - 2.2e-07 30.8 8.6 1.6e-06 28.1 0.6 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EPS32189.1 - 9.6e-05 22.4 0.5 9.6e-05 22.4 0.3 3.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EPS32189.1 - 0.0001 22.4 0.7 0.0001 22.4 0.5 3.7 4 1 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EPS32189.1 - 0.002 17.9 0.1 0.32 10.9 0.0 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EPS32189.1 - 0.28 11.3 9.2 0.15 12.2 0.3 3.5 4 1 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EPS32189.1 - 0.39 10.9 3.8 8.3 6.7 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EPS32189.1 - 0.67 10.1 3.9 6.4 6.9 0.1 2.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) SNF2_N PF00176.18 EPS32190.1 - 3e-65 219.9 0.1 5e-65 219.2 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 EPS32190.1 - 8.9e-23 79.7 3.2 2.1e-13 49.6 0.3 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EPS32190.1 - 5.7e-14 51.7 0.0 3.8e-13 49.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4208 PF13907.1 EPS32190.1 - 7.8e-12 45.3 0.9 2.7e-11 43.5 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) AAA_22 PF13401.1 EPS32190.1 - 0.055 13.6 0.0 0.57 10.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EPS32191.1 - 2.2e-34 118.6 0.0 5.1e-16 59.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter RLI PF04068.10 EPS32191.1 - 1.8e-14 53.0 5.6 1.8e-14 53.0 3.8 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 EPS32191.1 - 6.7e-14 52.5 3.5 0.043 13.7 0.0 4.3 2 2 2 4 4 4 4 AAA domain SMC_N PF02463.14 EPS32191.1 - 9e-11 41.4 2.1 0.0015 17.7 0.0 4.0 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EPS32191.1 - 1.6e-06 27.4 0.1 1.4 7.8 0.0 4.3 4 1 1 5 5 5 2 AAA ATPase domain Fer4 PF00037.22 EPS32191.1 - 1.8e-05 24.1 2.9 1.8e-05 24.1 2.0 2.7 3 0 0 3 3 3 1 4Fe-4S binding domain AAA_17 PF13207.1 EPS32191.1 - 1.9e-05 25.4 0.9 0.32 11.8 0.0 3.3 2 2 0 2 2 2 2 AAA domain AAA PF00004.24 EPS32191.1 - 2.1e-05 24.7 0.0 0.032 14.4 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPS32191.1 - 3.7e-05 23.8 0.0 0.014 15.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EPS32191.1 - 5.6e-05 22.5 0.4 0.061 12.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EPS32191.1 - 0.00012 21.2 2.7 0.24 10.5 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 EPS32191.1 - 0.00014 22.1 0.0 0.41 10.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain Fer4_6 PF12837.2 EPS32191.1 - 0.00065 19.4 10.6 0.0018 18.0 1.3 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain VirE PF05272.6 EPS32191.1 - 0.00067 19.1 0.1 1.5 8.2 0.0 2.5 2 0 0 2 2 2 2 Virulence-associated protein E Miro PF08477.8 EPS32191.1 - 0.00089 19.7 0.0 0.067 13.6 0.0 2.8 3 0 0 3 3 2 1 Miro-like protein AAA_33 PF13671.1 EPS32191.1 - 0.0011 18.8 0.0 0.074 12.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EPS32191.1 - 0.0012 18.6 0.9 0.18 11.4 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EPS32191.1 - 0.0018 18.3 0.7 0.77 9.9 0.0 3.0 3 0 0 3 3 2 1 RNA helicase UPF0079 PF02367.12 EPS32191.1 - 0.0019 17.8 0.2 0.026 14.1 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Fer4_21 PF14697.1 EPS32191.1 - 0.0021 17.8 11.7 0.0042 16.8 8.1 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Rad17 PF03215.10 EPS32191.1 - 0.0022 16.7 0.0 0.047 12.3 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_23 PF13476.1 EPS32191.1 - 0.0024 18.2 0.1 0.15 12.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 EPS32191.1 - 0.0033 16.9 2.4 0.11 11.9 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EPS32191.1 - 0.0036 16.7 0.1 2.4 7.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EPS32191.1 - 0.005 16.5 1.9 0.43 10.2 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_13 PF13166.1 EPS32191.1 - 0.006 15.1 1.1 0.0077 14.7 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EPS32191.1 - 0.012 15.6 0.1 3.1 7.7 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain Fer4_10 PF13237.1 EPS32191.1 - 0.019 14.7 1.5 0.019 14.7 1.0 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain SbcCD_C PF13558.1 EPS32191.1 - 0.022 14.6 0.1 11 5.9 0.0 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Fer4_9 PF13187.1 EPS32191.1 - 0.032 14.4 2.1 0.032 14.4 1.5 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_7 PF12838.2 EPS32191.1 - 0.033 14.5 1.9 0.033 14.5 1.3 2.3 1 1 2 3 3 3 0 4Fe-4S dicluster domain AAA_28 PF13521.1 EPS32191.1 - 0.034 14.0 0.1 2.8 7.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain Fer4_8 PF13183.1 EPS32191.1 - 0.037 14.0 7.7 0.098 12.7 5.4 1.6 1 1 0 1 1 1 0 4Fe-4S dicluster domain Thymidylate_kin PF02223.12 EPS32191.1 - 0.039 13.3 0.1 8.8 5.6 0.0 2.6 2 0 0 2 2 2 0 Thymidylate kinase Fer4_16 PF13484.1 EPS32191.1 - 0.04 14.6 0.1 0.04 14.6 0.1 2.6 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain AAA_14 PF13173.1 EPS32191.1 - 0.052 13.4 1.1 4.3 7.2 0.0 3.1 2 2 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EPS32191.1 - 0.057 12.8 2.1 0.091 12.2 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.9 EPS32191.1 - 0.097 12.3 0.0 4.8 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) KaiC PF06745.8 EPS32191.1 - 0.12 11.5 0.1 0.26 10.3 0.1 1.5 1 0 0 1 1 1 0 KaiC NB-ARC PF00931.17 EPS32191.1 - 0.12 11.2 0.2 8.5 5.1 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.1 EPS32191.1 - 0.15 11.6 2.1 0.85 9.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EPS32191.1 - 0.15 11.6 0.2 3.4 7.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Fer4_2 PF12797.2 EPS32191.1 - 0.5 10.3 12.7 0.23 11.4 1.8 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_17 PF13534.1 EPS32191.1 - 7.4 7.0 11.0 0.31 11.4 0.8 2.6 1 1 1 2 2 2 0 4Fe-4S dicluster domain Glyco_hydro_28 PF00295.12 EPS32193.1 - 1.4e-94 316.7 18.8 1.6e-94 316.5 13.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EPS32193.1 - 0.018 14.8 35.2 0.31 10.7 24.4 2.6 1 1 0 1 1 1 0 Right handed beta helix region MCR_alpha PF02249.12 EPS32193.1 - 0.071 13.1 0.4 0.071 13.1 0.3 2.0 2 0 0 2 2 2 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain FF PF01846.14 EPS32195.1 - 8.5e-56 185.7 23.9 1.8e-14 53.3 0.4 7.3 6 1 0 6 6 6 6 FF domain WW PF00397.21 EPS32195.1 - 1.1e-17 63.5 10.1 1.6e-08 34.2 0.2 2.6 2 0 0 2 2 2 2 WW domain EMP24_GP25L PF01105.19 EPS32195.1 - 1.1 8.9 5.9 0.098 12.3 0.4 2.0 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DNA_pack_N PF02500.10 EPS32195.1 - 4.5 6.7 6.7 1.3 8.5 2.0 1.9 2 0 0 2 2 2 0 Probable DNA packing protein, N-terminus Trs65 PF12735.2 EPS32196.1 - 3e-93 312.4 0.0 3.8e-93 312.1 0.0 1.1 1 0 0 1 1 1 1 TRAPP trafficking subunit Trs65 Mpv17_PMP22 PF04117.7 EPS32197.1 - 3.1e-22 77.9 0.1 3.1e-22 77.9 0.1 2.4 3 0 0 3 3 3 1 Mpv17 / PMP22 family PGK PF00162.14 EPS32198.1 - 1.2e-150 501.4 2.4 1.3e-150 501.2 1.7 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase TroA PF01297.12 EPS32198.1 - 0.086 12.0 0.3 1.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Periplasmic solute binding protein family DSS1_SEM1 PF05160.8 EPS32200.1 - 1.5e-25 88.7 15.2 2.1e-25 88.2 10.5 1.2 1 0 0 1 1 1 1 DSS1/SEM1 family Cwf_Cwc_15 PF04889.7 EPS32200.1 - 0.62 9.7 7.8 0.68 9.5 5.4 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF3808 PF10300.4 EPS32201.1 - 3.6e-156 520.4 0.0 4.2e-156 520.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) MFS_1 PF07690.11 EPS32202.1 - 1.8e-38 132.1 65.9 1.5e-36 125.8 26.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS32202.1 - 3.8e-08 32.3 10.7 3.8e-08 32.3 7.4 3.4 3 1 0 3 3 3 1 Sugar (and other) transporter AMP-binding PF00501.23 EPS32203.1 - 0 1030.3 0.0 2.6e-87 292.9 0.0 4.2 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.15 EPS32203.1 - 2.3e-242 801.6 0.0 3.4e-49 167.3 0.0 8.8 8 0 0 8 8 8 7 Condensation domain PP-binding PF00550.20 EPS32203.1 - 9.7e-48 160.3 7.7 5.7e-11 42.5 0.0 6.4 6 0 0 6 6 6 5 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EPS32203.1 - 1.7e-15 57.6 1.1 9.4e-05 23.2 0.1 5.3 5 0 0 5 5 5 3 AMP-binding enzyme C-terminal domain Transferase PF02458.10 EPS32203.1 - 0.00053 18.5 0.0 0.67 8.3 0.0 2.9 3 0 0 3 3 3 2 Transferase family ABC_tran PF00005.22 EPS32205.1 - 2.3e-47 160.7 0.0 4.9e-25 88.4 0.1 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EPS32205.1 - 5.1e-34 117.9 27.7 8.2e-21 74.6 10.0 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 EPS32205.1 - 4.6e-09 36.6 3.6 0.011 15.7 0.0 4.0 3 1 1 4 4 3 2 AAA domain SMC_N PF02463.14 EPS32205.1 - 1.5e-07 30.9 5.5 0.0077 15.4 1.6 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EPS32205.1 - 1.9e-07 30.6 0.2 0.0003 20.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EPS32205.1 - 4.2e-07 30.4 0.2 0.0019 18.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EPS32205.1 - 1.8e-06 27.4 1.2 0.00058 19.3 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 EPS32205.1 - 7.9e-06 25.1 0.1 0.0092 15.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EPS32205.1 - 1.6e-05 24.9 0.0 0.0035 17.3 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EPS32205.1 - 1.9e-05 24.7 0.9 0.066 13.3 0.1 2.9 2 1 0 2 2 2 2 AAA domain AAA PF00004.24 EPS32205.1 - 3e-05 24.2 0.4 0.063 13.4 0.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EPS32205.1 - 3.4e-05 23.7 0.0 0.057 13.3 0.0 2.7 2 1 0 2 2 2 2 AAA domain Miro PF08477.8 EPS32205.1 - 0.00012 22.5 0.5 0.46 10.9 0.1 2.6 2 0 0 2 2 2 2 Miro-like protein RNA_helicase PF00910.17 EPS32205.1 - 0.00017 21.7 0.3 0.027 14.6 0.0 2.7 2 0 0 2 2 2 1 RNA helicase ATP-synt_ab PF00006.20 EPS32205.1 - 0.00055 19.5 0.1 0.52 9.7 0.0 2.3 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain T2SE PF00437.15 EPS32205.1 - 0.0015 17.5 0.4 0.76 8.6 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein MMR_HSR1 PF01926.18 EPS32205.1 - 0.0018 18.2 0.1 0.42 10.5 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_10 PF12846.2 EPS32205.1 - 0.0018 17.7 1.9 0.075 12.4 0.0 2.5 2 1 0 2 2 2 1 AAA-like domain SbcCD_C PF13558.1 EPS32205.1 - 0.0027 17.5 0.1 5.9 6.8 0.0 3.2 3 0 0 3 3 2 0 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.13 EPS32205.1 - 0.0041 16.6 0.1 1.3 8.4 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_17 PF13207.1 EPS32205.1 - 0.0049 17.6 3.0 1.2 9.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EPS32205.1 - 0.011 15.4 1.6 0.95 9.1 0.1 3.0 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 EPS32205.1 - 0.014 15.1 0.0 0.57 9.8 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase NACHT PF05729.7 EPS32205.1 - 0.017 14.7 0.4 0.72 9.5 0.0 2.6 2 0 0 2 2 2 0 NACHT domain MobB PF03205.9 EPS32205.1 - 0.021 14.5 1.6 5.7 6.6 0.1 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 EPS32205.1 - 0.034 13.7 0.1 12 5.3 0.0 2.8 2 1 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 EPS32205.1 - 0.034 13.6 0.1 3.1 7.2 0.0 2.7 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.1 EPS32205.1 - 0.055 13.7 0.8 9.1 6.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EPS32205.1 - 0.07 12.2 1.3 4.1 6.4 0.1 2.5 2 0 0 2 2 2 0 Zeta toxin UPF0079 PF02367.12 EPS32205.1 - 0.072 12.7 0.4 6.5 6.4 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NB-ARC PF00931.17 EPS32205.1 - 0.073 11.9 0.2 8.1 5.2 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_14 PF13173.1 EPS32205.1 - 0.092 12.6 0.6 1.2 9.0 0.0 2.8 2 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EPS32205.1 - 0.13 11.7 2.9 0.57 9.6 0.2 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 EPS32205.1 - 0.15 11.0 0.3 4.1 6.3 0.0 2.2 2 0 0 2 2 2 0 Septin DUF815 PF05673.8 EPS32205.1 - 0.15 10.9 0.6 1 8.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 EPS32205.1 - 0.16 11.5 1.1 11 5.5 0.2 2.4 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EPS32205.1 - 0.18 11.5 0.2 3.2 7.5 0.0 2.3 2 0 0 2 2 2 0 Dynamin family PRK PF00485.13 EPS32205.1 - 0.25 10.8 0.7 11 5.5 0.2 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NTPase_1 PF03266.10 EPS32205.1 - 0.37 10.4 1.3 13 5.4 0.1 2.5 2 0 0 2 2 2 0 NTPase Rad17 PF03215.10 EPS32205.1 - 0.44 9.1 1.4 0.74 8.4 0.3 1.7 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein cobW PF02492.14 EPS32205.1 - 0.57 9.5 2.9 13 5.1 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Nup160 PF11715.3 EPS32207.1 - 2.7e-156 520.9 3.9 3.8e-156 520.4 2.7 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Rad51 PF08423.6 EPS32208.1 - 4.7e-138 458.2 0.0 5.9e-138 457.9 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EPS32208.1 - 3.4e-13 49.4 0.0 4.8e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 EPS32208.1 - 2.4e-08 33.4 0.0 3.3e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.1 EPS32208.1 - 9.1e-08 32.1 0.1 2.8e-07 30.6 0.1 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain KaiC PF06745.8 EPS32208.1 - 1.7e-05 24.0 0.2 3.8e-05 22.9 0.1 1.6 1 1 0 1 1 1 1 KaiC PAXNEB PF05625.6 EPS32208.1 - 0.025 13.4 0.3 0.057 12.2 0.1 1.6 2 0 0 2 2 2 0 PAXNEB protein DnaB_C PF03796.10 EPS32208.1 - 0.054 12.3 0.1 0.1 11.4 0.0 1.4 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain HHH PF00633.18 EPS32208.1 - 0.092 12.4 0.0 0.23 11.2 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif Fungal_trans PF04082.13 EPS32212.1 - 4.4e-14 51.9 0.0 1.2e-13 50.6 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS32212.1 - 2.6e-06 27.2 14.9 4e-06 26.6 10.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.16 EPS32213.1 - 3.7e-55 186.7 0.0 4.7e-55 186.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SUFU PF05076.8 EPS32213.1 - 0.09 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Suppressor of fused protein (SUFU) Zn_clus PF00172.13 EPS32214.1 - 0.00015 21.6 8.8 0.00029 20.6 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain 3HCDH_N PF02737.13 EPS32215.1 - 2.5e-25 89.1 0.0 4.9e-25 88.2 0.0 1.5 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EPS32215.1 - 3.5e-20 72.2 0.0 5.9e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.18 EPS32215.1 - 0.0015 18.3 0.1 0.0025 17.5 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 EPS32215.1 - 0.022 14.2 0.0 0.056 12.8 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Saccharop_dh PF03435.13 EPS32215.1 - 0.038 12.9 0.0 0.054 12.4 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase TrkA_N PF02254.13 EPS32215.1 - 0.056 13.4 0.0 0.14 12.1 0.0 1.6 1 1 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.1 EPS32215.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Aa_trans PF01490.13 EPS32216.1 - 3.9e-20 71.7 26.9 5e-13 48.3 7.1 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Bacteriocin_IId PF09221.5 EPS32216.1 - 0.025 14.5 1.6 0.043 13.7 0.1 2.1 2 0 0 2 2 2 0 Bacteriocin class IId cyclical uberolysin-like ECH PF00378.15 EPS32217.1 - 3.8e-31 108.0 0.0 6.5e-31 107.3 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family CPL PF08144.6 EPS32220.1 - 1e-15 57.8 0.2 8.5e-15 54.8 0.0 2.7 1 1 1 2 2 2 1 CPL (NUC119) domain Daxx PF03344.10 EPS32220.1 - 0.0035 15.9 24.5 0.0057 15.2 17.0 1.3 1 0 0 1 1 1 1 Daxx Family PUF PF00806.14 EPS32220.1 - 0.048 13.1 0.0 29 4.3 0.0 3.7 3 0 0 3 3 3 0 Pumilio-family RNA binding repeat zf-BED PF02892.10 EPS32224.1 - 0.0029 17.3 0.4 0.0029 17.3 0.2 1.8 2 0 0 2 2 2 1 BED zinc finger Zn_clus PF00172.13 EPS32224.1 - 0.06 13.2 8.3 0.15 11.9 5.8 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_6 PF13912.1 EPS32224.1 - 0.076 12.9 0.9 0.84 9.6 0.6 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger HypA PF01155.14 EPS32224.1 - 2.3 7.9 5.0 27 4.4 1.8 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DNA_pol_B_palm PF14792.1 EPS32226.1 - 5.3e-30 103.7 0.0 1.6e-29 102.2 0.0 1.9 2 0 0 2 2 2 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 EPS32226.1 - 1.4e-20 72.7 0.1 5.1e-20 70.9 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase beta thumb HHH_8 PF14716.1 EPS32226.1 - 7.7e-18 64.4 0.1 2.5e-17 62.8 0.1 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 EPS32226.1 - 1.5e-16 59.6 0.1 5.7e-16 57.8 0.0 2.1 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda NTP_transf_2 PF01909.18 EPS32226.1 - 0.019 15.3 0.0 0.044 14.1 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain BRCT PF00533.21 EPS32226.1 - 0.02 15.0 0.0 0.045 13.8 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain ATP-synt_10 PF05176.9 EPS32227.1 - 2.2e-92 308.8 0.2 3.5e-92 308.2 0.0 1.3 2 0 0 2 2 2 1 ATP10 protein V-SNARE_C PF12352.3 EPS32228.1 - 7.8e-14 51.5 0.0 7.8e-14 51.5 0.0 2.8 4 0 0 4 4 4 1 Snare region anchored in the vesicle membrane C-terminus GOLGA2L5 PF15070.1 EPS32228.1 - 0.0073 14.8 6.0 0.0098 14.4 4.1 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 DUF2046 PF09755.4 EPS32228.1 - 0.0085 15.0 3.0 0.01 14.7 1.4 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) IncA PF04156.9 EPS32228.1 - 0.023 14.3 10.5 0.039 13.5 7.3 1.4 1 0 0 1 1 1 0 IncA protein STAT_alpha PF01017.15 EPS32228.1 - 0.04 13.6 3.7 0.073 12.7 1.3 2.1 1 1 0 2 2 2 0 STAT protein, all-alpha domain Syntaxin-6_N PF09177.6 EPS32228.1 - 0.15 12.5 5.1 0.19 12.1 1.6 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF4570 PF15134.1 EPS32228.1 - 0.44 10.4 5.3 0.95 9.3 3.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) Dor1 PF04124.7 EPS32228.1 - 1.1 7.6 8.0 2.1 6.6 5.5 1.6 1 1 0 1 1 1 0 Dor1-like family DUF4613 PF15390.1 EPS32228.1 - 1.2 7.1 3.6 1.5 6.8 2.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) APG6 PF04111.7 EPS32228.1 - 1.9 7.4 7.2 1.4 7.8 3.8 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 GAS PF13851.1 EPS32228.1 - 2 7.5 7.4 3.8 6.6 4.4 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Ribosomal_L29 PF00831.18 EPS32229.1 - 1.9e-18 65.8 2.4 1.9e-18 65.8 1.7 1.6 2 0 0 2 2 2 1 Ribosomal L29 protein DUF3573 PF12097.3 EPS32229.1 - 0.037 12.6 0.9 0.047 12.3 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Cortex-I_coil PF09304.5 EPS32229.1 - 0.055 13.5 9.7 0.022 14.8 4.2 1.9 1 1 1 2 2 2 0 Cortexillin I, coiled coil H-K_ATPase_N PF09040.6 EPS32229.1 - 0.061 13.4 0.1 0.096 12.8 0.1 1.3 1 0 0 1 1 1 0 Gastric H+/K+-ATPase, N terminal domain Herpes_UL49_2 PF04823.7 EPS32229.1 - 0.099 12.6 0.4 0.16 11.9 0.3 1.4 1 0 0 1 1 1 0 Herpesvirus UL49 tegument protein CorA PF01544.13 EPS32229.1 - 0.1 11.6 2.6 0.13 11.3 1.8 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Snapin_Pallidin PF14712.1 EPS32229.1 - 0.14 12.4 5.3 0.21 11.9 2.6 1.9 1 1 1 2 2 2 0 Snapin/Pallidin Prefoldin PF02996.12 EPS32229.1 - 0.19 11.3 3.6 2.4 7.8 1.0 2.3 1 1 0 2 2 2 0 Prefoldin subunit Med16 PF11635.3 EPS32230.1 - 2e-173 578.2 0.0 2.4e-173 578.0 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 SIR2 PF02146.12 EPS32231.1 - 3.8e-29 101.6 0.0 7.4e-29 100.7 0.0 1.5 1 1 0 1 1 1 1 Sir2 family CBFD_NFYB_HMF PF00808.18 EPS32232.1 - 1.2e-05 25.2 0.0 2.9e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone BUD22 PF09073.5 EPS32232.1 - 0.042 12.9 29.9 0.059 12.4 20.7 1.3 1 0 0 1 1 1 0 BUD22 Daxx PF03344.10 EPS32232.1 - 0.99 7.8 43.0 1.5 7.2 29.8 1.2 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 EPS32232.1 - 1.4 6.8 25.3 2.2 6.2 17.6 1.4 1 0 0 1 1 1 0 CDC45-like protein CDC27 PF09507.5 EPS32232.1 - 1.7 7.8 25.8 2.4 7.2 17.9 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Spore_coat_CotO PF14153.1 EPS32232.1 - 2.6 7.4 18.8 4.8 6.5 13.0 1.6 1 0 0 1 1 1 0 Spore coat protein CotO CENP-T PF15511.1 EPS32232.1 - 4.2 6.5 34.6 2.8 7.1 22.5 1.7 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T GN3L_Grn1 PF08701.6 EPS32233.1 - 6.1e-25 86.9 19.7 1.8e-24 85.4 13.7 1.8 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 EPS32233.1 - 2.6e-23 82.1 0.8 3.7e-15 55.8 0.1 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 EPS32233.1 - 5.1e-07 29.6 6.2 0.0037 17.1 0.3 3.5 2 2 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.22 EPS32233.1 - 5.6e-07 29.1 0.0 0.024 14.0 0.0 2.6 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EPS32233.1 - 2.5e-06 26.8 0.1 6.2e-05 22.3 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EPS32233.1 - 0.00021 20.5 0.2 0.00037 19.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EPS32233.1 - 0.00078 18.6 0.3 0.23 10.5 0.0 2.4 2 0 0 2 2 2 2 AIG1 family Miro PF08477.8 EPS32233.1 - 0.0058 17.1 3.4 0.66 10.4 0.0 3.0 3 0 0 3 3 3 1 Miro-like protein Arf PF00025.16 EPS32233.1 - 0.049 12.8 0.0 1.1 8.5 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family ArgK PF03308.11 EPS32233.1 - 0.049 12.4 0.0 0.049 12.4 0.0 1.9 2 0 0 2 2 2 0 ArgK protein AAA_16 PF13191.1 EPS32233.1 - 0.074 13.0 3.5 0.24 11.3 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain ORC3_N PF07034.6 EPS32233.1 - 0.091 11.7 0.0 0.18 10.7 0.0 1.5 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 3 N-terminus AAA_18 PF13238.1 EPS32233.1 - 0.19 12.0 0.0 0.19 12.0 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EPS32233.1 - 0.52 11.1 0.0 0.52 11.1 0.0 2.9 2 1 0 2 2 2 0 AAA domain Nop14 PF04147.7 EPS32233.1 - 1.2 6.9 25.9 0.44 8.3 16.2 1.5 2 0 0 2 2 2 0 Nop14-like family Daxx PF03344.10 EPS32233.1 - 4 5.7 18.4 6.6 5.0 12.7 1.3 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 EPS32233.1 - 4.4 5.2 11.8 7.5 4.4 8.2 1.4 1 0 0 1 1 1 0 CDC45-like protein HAD_2 PF13419.1 EPS32234.1 - 7.2e-16 58.9 0.0 9.9e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPS32234.1 - 2.2e-09 38.0 0.0 2.7e-07 31.2 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EPS32234.1 - 1.1e-08 34.6 0.0 1.9e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EPS32234.1 - 0.052 13.7 0.2 0.11 12.5 0.1 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Homeobox PF00046.24 EPS32239.1 - 9.7e-17 60.3 2.4 2.3e-16 59.1 1.7 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EPS32239.1 - 1e-06 28.3 0.4 2.3e-06 27.1 0.2 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 EPS32239.1 - 0.3 10.1 2.4 0.97 8.5 0.1 2.4 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez His_Phos_1 PF00300.17 EPS32240.1 - 1.5e-10 41.3 0.0 2.9e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF2823 PF11034.3 EPS32242.1 - 4.6e-35 119.5 13.3 5.1e-35 119.4 9.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) Y_phosphatase3 PF13350.1 EPS32244.1 - 3.9e-38 131.2 0.0 1e-37 129.9 0.0 1.7 2 1 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EPS32244.1 - 3.6e-11 43.0 0.1 9.4e-11 41.6 0.1 1.7 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region ALF PF03752.8 EPS32244.1 - 0.003 17.3 0.1 0.0085 15.9 0.1 1.8 1 0 0 1 1 1 1 Short repeats of unknown function PTPlike_phytase PF14566.1 EPS32244.1 - 0.033 14.2 0.0 0.075 13.0 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase PF00102.22 EPS32244.1 - 0.12 11.7 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase polyprenyl_synt PF00348.12 EPS32245.1 - 3.8e-53 179.9 0.0 6.2e-53 179.2 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase Prenyltrans_2 PF13249.1 EPS32245.1 - 5.5e-13 49.3 1.1 0.0034 17.7 0.1 4.8 3 1 1 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EPS32245.1 - 8.1e-11 41.9 0.1 0.00045 20.1 0.0 4.5 5 0 0 5 5 5 2 Prenyltransferase-like Prenyltrans PF00432.16 EPS32245.1 - 3.3e-05 23.3 0.0 1.1 8.8 0.0 4.0 3 1 0 3 3 3 2 Prenyltransferase and squalene oxidase repeat p450 PF00067.17 EPS32246.1 - 1.8e-72 244.3 0.0 2.2e-72 244.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4538 PF15061.1 EPS32246.1 - 0.13 11.5 0.8 0.29 10.4 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) p450 PF00067.17 EPS32247.1 - 2.7e-71 240.5 0.0 3.5e-71 240.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 EPS32248.1 - 6.3e-24 84.7 1.6 1.3e-23 83.7 1.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPS32248.1 - 1.5e-11 44.2 2.3 1.4e-10 41.1 1.5 2.0 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EPS32248.1 - 5e-08 33.0 0.0 7e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EPS32248.1 - 2.8e-05 24.2 0.0 4.6e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPS32248.1 - 4.2e-05 23.0 0.0 6.1e-05 22.5 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EPS32248.1 - 0.035 13.8 0.1 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NADH_dh_m_C1 PF15088.1 EPS32248.1 - 0.046 13.2 0.0 0.085 12.3 0.0 1.4 1 0 0 1 1 1 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial TP_methylase PF00590.15 EPS32248.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Tetrapyrrole (Corrin/Porphyrin) Methylases CRC_subunit PF08624.5 EPS32249.1 - 6.5e-55 184.8 0.0 1.2e-54 184.0 0.0 1.4 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit AAA_23 PF13476.1 EPS32249.1 - 0.031 14.5 2.1 0.056 13.7 1.4 1.4 1 0 0 1 1 1 0 AAA domain PPP4R2 PF09184.6 EPS32249.1 - 9.5 5.6 10.7 1.7 8.1 4.5 1.8 2 0 0 2 2 2 0 PPP4R2 TMF_TATA_bd PF12325.3 EPS32253.1 - 7.4e-43 145.1 10.8 7.4e-43 145.1 7.5 6.1 3 2 4 7 7 7 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 EPS32253.1 - 8.8e-10 38.2 13.9 8.8e-10 38.2 9.7 7.7 3 2 3 7 7 7 1 TATA element modulatory factor 1 DNA binding Filament PF00038.16 EPS32253.1 - 0.0056 16.1 22.6 0.0056 16.1 15.7 4.1 2 1 1 3 3 3 2 Intermediate filament protein DUF4248 PF14053.1 EPS32253.1 - 0.64 9.6 9.2 0.074 12.6 0.5 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4248) Atg14 PF10186.4 EPS32253.1 - 6.5 5.6 81.6 0.29 10.0 11.9 5.4 2 1 3 5 5 5 0 UV radiation resistance protein and autophagy-related subunit 14 V-ATPase_H_N PF03224.9 EPS32254.1 - 8.1e-81 271.5 0.0 1.7e-80 270.5 0.0 1.5 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 EPS32254.1 - 1.1e-39 135.0 3.5 1.1e-39 134.9 0.0 2.7 4 0 0 4 4 4 1 V-ATPase subunit H HEAT_EZ PF13513.1 EPS32254.1 - 0.16 12.5 4.7 5.8 7.5 0.1 4.3 4 1 1 5 5 5 0 HEAT-like repeat Fungal_trans_2 PF11951.3 EPS32255.1 - 2.2e-58 197.6 4.0 2.9e-58 197.3 2.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS32255.1 - 3.5e-08 33.2 6.8 5.8e-08 32.5 4.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APH PF01636.18 EPS32256.1 - 4.6e-07 29.8 0.0 5.8e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family GCV_T PF01571.16 EPS32257.1 - 2.3e-57 193.7 0.0 3e-57 193.3 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EPS32257.1 - 6.9e-20 70.8 0.2 1.7e-19 69.6 0.1 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain POP1 PF06978.6 EPS32257.1 - 0.077 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 Aa_trans PF01490.13 EPS32258.1 - 5.8e-28 97.4 32.9 6.8e-28 97.2 22.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CBF PF03914.12 EPS32259.1 - 7.2e-47 158.8 0.9 2.9e-46 156.9 0.0 2.5 2 0 0 2 2 2 1 CBF/Mak21 family tRNA-synt_2b PF00587.20 EPS32260.1 - 1.7e-33 115.5 0.0 2.6e-33 115.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EPS32260.1 - 5.6e-15 55.0 0.0 1.3e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain Rod_C PF10493.4 EPS32260.1 - 0.06 11.6 0.0 0.083 11.1 0.0 1.1 1 0 0 1 1 1 0 Rough deal protein C-terminal region tRNA-synt_2 PF00152.15 EPS32260.1 - 0.062 12.0 0.0 0.089 11.5 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) Prefoldin PF02996.12 EPS32261.1 - 3.6e-24 84.7 0.3 4.6e-24 84.3 0.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 EPS32261.1 - 0.032 13.9 0.7 0.78 9.5 0.2 2.0 2 0 0 2 2 2 0 Prefoldin subunit NPV_P10 PF05531.7 EPS32261.1 - 0.16 12.2 0.8 2.5 8.4 0.1 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Sec2p PF06428.6 EPS32261.1 - 0.19 11.5 1.6 14 5.6 0.2 2.2 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p AAA PF00004.24 EPS32263.1 - 3.6e-14 53.1 0.0 6.9e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EPS32263.1 - 1e-09 38.6 0.0 4.3e-09 36.6 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EPS32263.1 - 2.3e-08 34.2 0.0 6.4e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPS32263.1 - 1.2e-05 26.0 0.1 0.00031 21.5 0.0 3.2 5 0 0 5 5 3 1 AAA domain BAH PF01426.13 EPS32263.1 - 0.00016 21.3 0.0 0.00037 20.2 0.0 1.5 1 0 0 1 1 1 1 BAH domain AAA_19 PF13245.1 EPS32263.1 - 0.0014 18.3 1.8 0.0031 17.2 0.2 2.4 2 0 0 2 2 2 1 Part of AAA domain AAA_28 PF13521.1 EPS32263.1 - 0.0015 18.5 0.0 0.0043 17.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EPS32263.1 - 0.0062 16.2 0.0 0.017 14.8 0.0 1.7 1 1 0 1 1 1 1 NACHT domain DUF2075 PF09848.4 EPS32263.1 - 0.0066 15.4 0.0 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_11 PF13086.1 EPS32263.1 - 0.01 15.4 0.0 0.029 13.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EPS32263.1 - 0.019 14.8 0.0 0.2 11.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_32 PF13654.1 EPS32263.1 - 0.02 13.5 0.0 0.034 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EPS32263.1 - 0.022 15.0 0.0 0.063 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain Zot PF05707.7 EPS32263.1 - 0.03 13.7 0.0 0.081 12.3 0.0 1.7 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) PIF1 PF05970.9 EPS32263.1 - 0.041 12.8 0.0 0.077 11.9 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase Kinesin PF00225.18 EPS32263.1 - 0.074 11.7 0.0 0.13 10.9 0.0 1.3 1 0 0 1 1 1 0 Kinesin motor domain Arch_ATPase PF01637.13 EPS32263.1 - 0.076 12.6 0.0 0.68 9.5 0.0 2.1 1 1 0 1 1 1 0 Archaeal ATPase WD40 PF00400.27 EPS32264.1 - 2.3e-50 166.7 13.5 4.8e-09 35.7 0.0 7.5 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 EPS32264.1 - 0.003 15.7 4.1 9.1 4.2 0.0 4.6 1 1 3 4 4 4 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EPS32264.1 - 0.023 14.1 0.3 1.5 8.2 0.1 2.5 2 1 0 2 2 2 0 PQQ-like domain Ank_2 PF12796.2 EPS32265.1 - 1.4e-39 134.3 1.5 4.2e-19 68.6 0.1 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EPS32265.1 - 9.6e-34 113.5 1.6 6.6e-07 28.8 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 EPS32265.1 - 1e-31 108.2 3.1 9e-11 41.6 0.1 4.7 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPS32265.1 - 4.5e-27 91.4 0.2 0.00014 21.7 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 EPS32265.1 - 4.6e-27 93.8 0.6 6.1e-10 39.3 0.0 4.1 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Plectin PF00681.15 EPS32265.1 - 0.017 14.6 0.0 0.033 13.6 0.0 1.5 1 0 0 1 1 1 0 Plectin repeat Shal-type PF11601.3 EPS32265.1 - 0.026 14.0 0.8 0.1 12.1 0.0 2.2 2 0 0 2 2 2 0 Shal-type voltage-gated potassium channels Pyr_redox_3 PF13738.1 EPS32266.1 - 6e-27 95.0 0.0 9.9e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EPS32266.1 - 8e-20 70.5 0.1 8.3e-19 67.1 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EPS32266.1 - 4.5e-11 42.2 0.1 2.4e-07 29.9 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EPS32266.1 - 6.5e-10 39.2 0.0 2.2e-09 37.5 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPS32266.1 - 1.4e-06 28.2 0.0 3.6e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EPS32266.1 - 0.00014 22.1 0.1 0.42 11.0 0.0 3.3 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EPS32266.1 - 0.00023 21.2 0.0 0.54 10.3 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 EPS32266.1 - 0.00052 19.0 0.0 0.0019 17.1 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EPS32266.1 - 0.00062 18.9 0.0 0.0013 17.8 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 EPS32266.1 - 0.0011 18.7 0.0 0.0083 15.9 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 EPS32266.1 - 0.0017 18.6 0.0 0.45 10.7 0.0 3.0 2 1 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_2 PF00890.19 EPS32266.1 - 0.024 13.5 0.0 0.036 12.9 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 EPS32266.1 - 0.2 10.1 0.2 0.34 9.3 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein Filament PF00038.16 EPS32267.1 - 5.8e-05 22.7 4.4 5.8e-05 22.7 3.0 7.3 5 1 0 5 5 5 2 Intermediate filament protein DUF3658 PF12395.3 EPS32267.1 - 0.1 12.1 0.0 0.1 12.1 0.0 4.5 6 0 0 6 6 6 0 Protein of unknown function Borrelia_orfA PF02414.10 EPS32267.1 - 0.25 10.4 0.6 0.5 9.4 0.4 1.4 1 0 0 1 1 1 0 Borrelia ORF-A Apq12 PF12716.2 EPS32268.1 - 6.5e-12 44.9 21.2 3.9e-10 39.2 14.7 2.3 1 1 0 1 1 1 1 Nuclear pore assembly and biogenesis ATP_bind_1 PF03029.12 EPS32269.1 - 1e-75 254.3 0.1 1.2e-75 254.1 0.1 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EPS32269.1 - 2.2e-06 28.4 0.0 7.3e-06 26.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EPS32269.1 - 0.00024 20.9 0.0 0.00049 20.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPS32269.1 - 0.00031 20.7 0.0 0.0014 18.6 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain T2SE PF00437.15 EPS32269.1 - 0.00051 19.0 0.0 0.001 18.0 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_33 PF13671.1 EPS32269.1 - 0.00063 19.6 0.0 0.0014 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_31 PF13614.1 EPS32269.1 - 0.0016 18.4 0.1 0.012 15.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EPS32269.1 - 0.0025 17.9 0.0 0.0064 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EPS32269.1 - 0.004 16.6 0.0 0.011 15.1 0.0 1.9 1 1 0 1 1 1 1 AAA-like domain AAA_19 PF13245.1 EPS32269.1 - 0.0045 16.6 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 EPS32269.1 - 0.0058 16.7 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 RNA helicase UPF0079 PF02367.12 EPS32269.1 - 0.0094 15.5 0.0 0.032 13.8 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA PF00004.24 EPS32269.1 - 0.011 15.9 0.0 0.025 14.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 EPS32269.1 - 0.012 15.0 0.0 0.028 13.9 0.0 1.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family MobB PF03205.9 EPS32269.1 - 0.014 15.1 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 EPS32269.1 - 0.021 14.2 0.1 0.4 10.1 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.22 EPS32269.1 - 0.022 14.2 0.0 3.4 7.0 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Zeta_toxin PF06414.7 EPS32269.1 - 0.022 13.8 0.0 0.037 13.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Sigma54_activat PF00158.21 EPS32269.1 - 0.024 14.0 0.0 0.043 13.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 EPS32269.1 - 0.027 13.9 0.0 0.05 13.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.7 EPS32269.1 - 0.028 14.0 0.0 0.054 13.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Septin PF00735.13 EPS32269.1 - 0.033 13.2 0.0 0.053 12.5 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_29 PF13555.1 EPS32269.1 - 0.035 13.6 0.0 0.067 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain KaiC PF06745.8 EPS32269.1 - 0.035 13.2 0.0 0.08 12.0 0.0 1.6 2 0 0 2 2 1 0 KaiC ABC_tran PF00005.22 EPS32269.1 - 0.036 14.3 0.0 0.1 12.9 0.0 1.7 2 0 0 2 2 1 0 ABC transporter CbiA PF01656.18 EPS32269.1 - 0.036 13.4 0.0 0.058 12.7 0.0 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 EPS32269.1 - 0.036 13.0 0.0 0.07 12.1 0.0 1.4 1 0 0 1 1 1 0 Anion-transporting ATPase MMR_HSR1 PF01926.18 EPS32269.1 - 0.041 13.8 0.0 0.11 12.4 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_30 PF13604.1 EPS32269.1 - 0.043 13.3 0.0 0.098 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EPS32269.1 - 0.054 13.8 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 EPS32269.1 - 0.064 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_5 PF07728.9 EPS32269.1 - 0.066 12.9 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SRP54 PF00448.17 EPS32269.1 - 0.074 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain KAP_NTPase PF07693.9 EPS32269.1 - 0.11 11.4 0.0 0.13 11.1 0.0 1.6 1 1 0 1 1 1 0 KAP family P-loop domain DUF258 PF03193.11 EPS32269.1 - 0.12 11.6 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 EPS32269.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 EPS32269.1 - 0.14 11.8 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase S-AdoMet_synt_C PF02773.11 EPS32270.1 - 5.3e-78 259.4 1.1 1.3e-77 258.1 0.2 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EPS32270.1 - 3.4e-45 152.8 0.0 6.8e-45 151.8 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EPS32270.1 - 9.5e-44 147.7 0.1 2.1e-43 146.5 0.1 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain DUF2312 PF10073.4 EPS32270.1 - 0.034 13.4 0.2 0.099 12.0 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) Lactamase_B_3 PF13483.1 EPS32270.1 - 0.062 12.9 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain GMC_oxred_N PF00732.14 EPS32272.1 - 2.5e-69 233.6 0.0 3.2e-69 233.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EPS32272.1 - 1.2e-38 132.6 0.0 2e-38 131.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EPS32272.1 - 3.3e-05 23.8 0.2 8.6e-05 22.4 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EPS32272.1 - 4.8e-05 22.3 0.8 0.0067 15.3 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EPS32272.1 - 0.00045 19.2 0.0 0.00083 18.3 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EPS32272.1 - 0.00051 19.0 0.2 0.00096 18.1 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EPS32272.1 - 0.0097 15.9 0.0 0.95 9.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EPS32272.1 - 0.017 13.6 0.1 0.024 13.1 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.9 EPS32272.1 - 0.018 14.9 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPS32272.1 - 0.05 12.7 0.2 0.085 11.9 0.2 1.3 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.11 EPS32272.1 - 0.052 12.9 0.1 0.14 11.6 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.22 EPS32272.1 - 0.091 13.1 0.2 0.27 11.6 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPS32272.1 - 0.16 11.7 0.1 2.6 7.7 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding SLD3 PF08639.5 EPS32273.1 - 4.5e-138 460.9 0.2 4.5e-138 460.9 0.1 1.4 2 0 0 2 2 2 1 DNA replication regulator SLD3 TEX13 PF15186.1 EPS32273.1 - 0.11 12.0 0.8 0.31 10.6 0.5 1.7 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family Glyco_hydro_92 PF07971.7 EPS32274.1 - 2.5e-165 550.9 0.2 3.1e-165 550.6 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 4HBT PF03061.17 EPS32275.1 - 1.4e-11 44.3 0.0 2.9e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Thioesterase superfamily APS_kinase PF01583.15 EPS32276.1 - 1.9e-69 232.3 0.0 2.4e-69 231.9 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 EPS32276.1 - 1.6e-07 31.3 0.0 2.8e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPS32276.1 - 2.9e-05 24.8 0.0 5e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPS32276.1 - 4.8e-05 23.6 0.0 8.6e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EPS32276.1 - 0.002 17.3 0.0 0.0028 16.9 0.0 1.4 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_16 PF13191.1 EPS32276.1 - 0.0022 18.0 0.1 0.0035 17.3 0.1 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 EPS32276.1 - 0.06 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EPS32276.1 - 0.096 11.7 0.0 0.22 10.5 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin V-ATPase_C PF03223.10 EPS32277.1 - 3.3e-122 407.9 0.0 3.7e-122 407.8 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C DUF4303 PF14136.1 EPS32277.1 - 0.11 12.1 0.5 0.62 9.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4303) RhoGAP PF00620.22 EPS32278.1 - 1.2e-47 161.2 0.0 3.4e-47 159.8 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 EPS32278.1 - 2.1e-14 53.3 17.6 1.6e-09 37.6 1.1 2.4 2 0 0 2 2 2 2 LIM domain ATG16 PF08614.6 EPS32278.1 - 4e-06 26.7 10.0 0.00095 19.0 0.4 2.8 2 0 0 2 2 2 2 Autophagy protein 16 (ATG16) CENP-H PF05837.7 EPS32278.1 - 0.27 11.4 7.3 0.19 11.9 0.1 3.4 2 1 1 3 3 3 0 Centromere protein H (CENP-H) DUF972 PF06156.8 EPS32278.1 - 0.65 10.3 9.4 0.09 13.1 1.2 3.1 1 1 0 2 2 2 0 Protein of unknown function (DUF972) Zn-ribbon_8 PF09723.5 EPS32278.1 - 0.78 9.7 19.0 0.28 11.1 1.3 4.0 4 0 0 4 4 4 0 Zinc ribbon domain TMF_TATA_bd PF12325.3 EPS32278.1 - 0.98 9.1 18.0 1.6 8.5 2.3 3.5 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding zinc_ribbon_2 PF13240.1 EPS32278.1 - 3.6 7.1 0.0 3.6 7.1 0.0 4.8 5 1 1 6 6 6 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 EPS32278.1 - 3.7 6.9 15.2 7.9 5.8 1.0 5.0 4 1 1 5 5 5 0 TFIIB zinc-binding Rootletin PF15035.1 EPS32278.1 - 5 7.0 13.6 14 5.5 9.4 1.7 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion CCDC155 PF14662.1 EPS32278.1 - 5.3 6.5 18.3 0.71 9.4 4.9 2.7 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 HAUS-augmin3 PF14932.1 EPS32278.1 - 8.3 5.5 12.7 0.26 10.4 3.7 2.0 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 DHquinase_I PF01487.10 EPS32279.1 - 1.2e-47 162.4 0.0 2.5e-47 161.3 0.0 1.5 2 0 0 2 2 2 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.6 EPS32279.1 - 6.3e-22 77.4 0.0 1.4e-21 76.3 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.17 EPS32279.1 - 7.2e-18 64.9 0.0 1.4e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Shikimate kinase Shikimate_DH PF01488.15 EPS32279.1 - 1.4e-11 44.6 0.0 4.5e-11 42.9 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase AAA_33 PF13671.1 EPS32279.1 - 0.00025 20.9 0.0 0.00073 19.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain F420_oxidored PF03807.12 EPS32279.1 - 0.0025 18.1 0.0 0.044 14.2 0.0 2.6 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent AAA_16 PF13191.1 EPS32279.1 - 0.0056 16.6 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EPS32279.1 - 0.013 16.3 0.0 0.035 14.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EPS32279.1 - 0.03 14.6 0.0 0.056 13.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DUF815 PF05673.8 EPS32279.1 - 0.096 11.5 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_25 PF13481.1 EPS32279.1 - 0.14 11.5 0.0 0.37 10.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Fungal_trans PF04082.13 EPS32280.1 - 9.3e-16 57.4 2.8 9.8e-16 57.3 0.4 2.0 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS32280.1 - 1.5e-09 37.5 13.2 2.4e-09 36.9 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHquinase_II PF01220.14 EPS32282.1 - 3e-62 208.0 0.0 3.5e-62 207.8 0.0 1.0 1 0 0 1 1 1 1 Dehydroquinase class II Inositol_P PF00459.20 EPS32283.1 - 2.7e-79 266.2 0.0 3.1e-79 266.0 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Shikimate_dh_N PF08501.6 EPS32284.1 - 4.7e-22 77.8 0.0 1.6e-21 76.1 0.0 1.9 1 1 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EPS32284.1 - 1.9e-14 53.8 0.0 3.1e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF987 PF06174.6 EPS32284.1 - 0.059 12.8 0.2 2.7 7.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF987) Sugar_tr PF00083.19 EPS32285.1 - 4.4e-136 454.0 25.7 5e-136 453.8 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS32285.1 - 6.1e-24 84.3 33.7 6.1e-24 84.3 23.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily AP_endonuc_2 PF01261.19 EPS32286.1 - 6.2e-28 97.5 0.0 7.8e-28 97.2 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Choline_kinase PF01633.15 EPS32287.1 - 7e-43 146.6 0.0 6.6e-42 143.4 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 EPS32287.1 - 1.2e-08 35.0 0.8 1.2e-08 35.0 0.6 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 EPS32287.1 - 0.0087 15.2 0.0 0.023 13.8 0.0 1.6 1 1 0 1 1 1 1 Ecdysteroid kinase CHORD PF04968.7 EPS32288.1 - 6.2e-54 180.1 16.6 6.3e-28 96.8 2.7 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.11 EPS32288.1 - 2.2e-15 56.9 0.1 3.3e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 CS domain peroxidase PF00141.18 EPS32289.1 - 7.2e-86 287.4 0.0 3.6e-44 150.9 0.0 2.2 2 0 0 2 2 2 2 Peroxidase Zn_clus PF00172.13 EPS32290.1 - 4.2e-09 36.1 6.8 7.3e-09 35.4 4.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EPS32290.1 - 1.3e-07 30.6 0.0 2e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.8 EPS32291.1 - 1.7e-37 129.1 4.0 1.7e-37 129.1 2.8 1.3 2 0 0 2 2 2 1 RTA1 like protein NAGidase PF07555.8 EPS32291.1 - 0.17 10.7 0.1 0.23 10.3 0.1 1.1 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase DUF4131 PF13567.1 EPS32291.1 - 1.3 8.4 8.7 5.5 6.3 0.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Fungal_trans PF04082.13 EPS32294.1 - 2.5e-17 62.5 1.0 3.5e-17 62.1 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EPS32295.1 - 1.8e-19 69.7 63.4 4.2e-18 65.1 40.6 3.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS32295.1 - 7.6e-10 37.9 14.2 7.6e-10 37.9 9.8 2.4 1 1 1 3 3 3 1 Sugar (and other) transporter PhyH PF05721.8 EPS32296.1 - 9.4e-06 25.8 0.4 0.00012 22.1 0.3 2.1 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Sugar_tr PF00083.19 EPS32297.1 - 5.8e-81 272.3 18.5 6.6e-81 272.1 12.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS32297.1 - 4.2e-34 117.8 43.1 2.6e-31 108.6 15.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3624 PF12292.3 EPS32297.1 - 0.45 10.9 7.0 1.1 9.6 0.7 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3624) Ferritin_2 PF13668.1 EPS32298.1 - 2.8e-08 33.8 0.0 4.5e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain Epsilon_antitox PF08998.6 EPS32298.1 - 0.056 13.4 0.4 0.098 12.6 0.2 1.4 1 0 0 1 1 1 0 Bacterial epsilon antitoxin Pec_lyase_C PF00544.14 EPS32299.1 - 5.4e-22 78.2 3.6 8.4e-22 77.6 2.5 1.4 1 0 0 1 1 1 1 Pectate lyase Amidase PF01425.16 EPS32301.1 - 1.8e-70 238.0 0.1 7.1e-66 222.8 0.0 2.1 2 0 0 2 2 2 2 Amidase NmrA PF05368.8 EPS32303.1 - 1.3e-16 60.6 0.1 1.8e-16 60.1 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPS32303.1 - 2.2e-08 34.3 0.0 4.1e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EPS32303.1 - 1.2e-06 28.5 0.1 2.6e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EPS32303.1 - 9.4e-05 22.1 0.0 0.0057 16.3 0.0 2.4 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EPS32303.1 - 0.00066 19.1 0.0 0.0017 17.8 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPS32303.1 - 0.00076 18.2 0.0 0.0012 17.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Fer2_3 PF13085.1 EPS32304.1 - 5.2e-31 106.7 0.0 8.2e-31 106.0 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 EPS32304.1 - 2.2e-09 37.5 6.1 2.2e-09 37.5 4.2 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EPS32304.1 - 7.1e-09 35.5 4.6 7.1e-09 35.5 3.2 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 EPS32304.1 - 0.00014 22.0 3.3 0.04 14.1 0.3 3.1 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_18 PF13746.1 EPS32304.1 - 0.00028 21.2 2.4 0.00028 21.2 1.6 2.7 2 2 1 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 EPS32304.1 - 0.00064 19.4 5.1 0.00064 19.4 3.5 2.2 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 EPS32304.1 - 0.0013 19.0 3.9 0.0013 19.0 2.7 2.3 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 EPS32304.1 - 0.0077 15.9 0.3 0.0077 15.9 0.2 2.2 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain Fer4_15 PF13459.1 EPS32304.1 - 1 9.9 5.8 0.74 10.4 0.1 2.7 3 0 0 3 3 3 0 4Fe-4S single cluster domain Methyltransf_2 PF00891.13 EPS32305.1 - 2.3e-13 49.8 0.2 3.8e-13 49.2 0.1 1.3 1 0 0 1 1 1 1 O-methyltransferase SnoaL_4 PF13577.1 EPS32305.1 - 2.7e-06 27.3 0.0 4e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain Methyltransf_2 PF00891.13 EPS32306.1 - 3.6e-10 39.4 0.0 5.4e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase F_bP_aldolase PF01116.15 EPS32308.1 - 1.4e-87 293.4 0.1 1.5e-87 293.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II DUF3588 PF12140.3 EPS32308.1 - 0.019 15.0 0.1 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3588) PTE PF02126.13 EPS32308.1 - 0.034 13.1 0.1 0.056 12.4 0.1 1.3 1 0 0 1 1 1 0 Phosphotriesterase family NAD_binding_11 PF14833.1 EPS32309.1 - 1.3e-40 138.2 5.5 8.6e-29 100.0 0.0 2.2 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 EPS32309.1 - 6.4e-39 133.4 0.1 6.4e-39 133.4 0.1 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EPS32309.1 - 5.5e-05 22.8 0.4 0.00013 21.6 0.0 1.8 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EPS32309.1 - 0.0019 18.5 0.2 0.0089 16.4 0.0 2.4 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent DUF1451 PF07295.6 EPS32309.1 - 0.061 13.0 0.4 0.11 12.2 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) UDPG_MGDP_dh_N PF03721.9 EPS32309.1 - 0.1 12.0 0.0 17 4.7 0.0 2.4 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Aldo_ket_red PF00248.16 EPS32312.1 - 6.3e-48 163.0 0.0 8.3e-48 162.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DNA_pol_B_palm PF14792.1 EPS32313.1 - 0.096 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase beta palm Eco57I PF07669.6 EPS32315.1 - 0.092 13.1 0.0 0.1 12.9 0.0 1.1 1 0 0 1 1 1 0 Eco57I restriction-modification methylase Glyco_hydro_92 PF07971.7 EPS32316.1 - 1.6e-156 521.9 0.4 2e-156 521.5 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Acetyltransf_1 PF00583.19 EPS32316.1 - 0.031 14.3 0.1 0.082 12.9 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Alpha-amylase_C PF02806.13 EPS32318.1 - 2e-24 85.5 0.0 4.2e-24 84.4 0.0 1.6 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 EPS32318.1 - 6.1e-18 65.2 0.0 6.6e-14 52.0 0.1 2.4 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 EPS32318.1 - 2.4e-17 62.7 0.1 5e-17 61.7 0.1 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) ATP-synt_ab PF00006.20 EPS32319.1 - 4.2e-62 209.4 0.0 6.1e-62 208.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EPS32319.1 - 1.9e-25 89.5 0.4 3.3e-25 88.7 0.3 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EPS32319.1 - 6.1e-24 84.0 1.6 3.6e-23 81.5 0.7 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain KaiC PF06745.8 EPS32319.1 - 0.0033 16.5 0.1 0.0055 15.8 0.1 1.4 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 EPS32319.1 - 0.0048 16.3 0.1 0.022 14.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EPS32319.1 - 0.011 15.5 0.0 0.032 13.9 0.0 1.7 2 0 0 2 2 2 0 Archaeal ATPase AAA_16 PF13191.1 EPS32319.1 - 0.012 15.6 0.4 0.45 10.4 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 EPS32319.1 - 0.015 15.5 0.1 1.1 9.4 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EPS32319.1 - 0.022 14.4 0.1 1 9.0 0.0 2.9 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EPS32319.1 - 0.029 14.0 0.2 0.073 12.7 0.0 1.7 2 0 0 2 2 2 0 NACHT domain DUF258 PF03193.11 EPS32319.1 - 0.067 12.3 0.1 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EPS32319.1 - 0.074 13.1 0.1 0.29 11.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EPS32319.1 - 0.079 11.7 0.6 0.29 9.9 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.17 EPS32319.1 - 0.097 12.8 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase COX4 PF02936.9 EPS32320.1 - 2.9e-51 172.9 0.8 3.3e-51 172.7 0.5 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1104 PF06518.6 EPS32320.1 - 0.14 12.3 0.2 0.25 11.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) DUF3106 PF11304.3 EPS32320.1 - 0.8 10.1 7.0 0.19 12.1 2.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3106) DUF1289 PF06945.8 EPS32320.1 - 3.5 7.1 5.9 3.8 7.0 0.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1289) Cofilin_ADF PF00241.15 EPS32321.1 - 5e-26 91.0 0.0 5.7e-26 90.8 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SpoVR PF04293.8 EPS32321.1 - 0.089 11.1 0.0 0.11 10.8 0.0 1.1 1 0 0 1 1 1 0 SpoVR like protein GST_N_3 PF13417.1 EPS32322.1 - 1.4e-18 66.9 0.1 2.4e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EPS32322.1 - 5.9e-15 55.0 0.0 1e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EPS32322.1 - 9.7e-13 48.1 0.0 2.2e-12 46.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 EPS32322.1 - 4.6e-05 23.3 0.0 8.5e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_C_2 PF13410.1 EPS32322.1 - 0.0033 17.2 0.0 0.0064 16.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NARP1 PF12569.3 EPS32322.1 - 0.06 12.1 0.0 0.079 11.6 0.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 SH3_9 PF14604.1 EPS32323.1 - 4.2e-07 29.4 0.1 8.5e-07 28.4 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EPS32323.1 - 0.00035 19.9 0.1 0.00076 18.8 0.1 1.6 1 0 0 1 1 1 1 SH3 domain Podoplanin PF05808.6 EPS32323.1 - 0.018 14.5 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Podoplanin SKG6 PF08693.5 EPS32323.1 - 0.046 13.0 4.9 0.11 11.8 3.4 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Pmp3 PF01679.12 EPS32324.1 - 1e-20 73.1 8.3 1.3e-20 72.8 5.8 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator She9_MDM33 PF05546.6 EPS32325.1 - 1.9e-92 308.5 9.5 2.8e-92 307.9 6.6 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family PsbH PF00737.15 EPS32325.1 - 0.019 14.4 0.9 0.038 13.5 0.6 1.4 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein UCR_TM PF02921.9 EPS32326.1 - 2.2e-20 72.6 1.6 4.7e-20 71.5 1.1 1.5 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 EPS32326.1 - 8.4e-17 60.5 0.0 1.4e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain CBFD_NFYB_HMF PF00808.18 EPS32327.1 - 6e-15 55.0 0.4 6e-15 55.0 0.2 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EPS32327.1 - 7.6e-05 22.7 0.1 0.00011 22.1 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Voltage_CLC PF00654.15 EPS32328.1 - 5.2e-91 305.3 29.5 5.2e-91 305.3 20.5 1.5 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EPS32328.1 - 4.6e-15 55.1 0.1 3.6e-06 26.6 0.0 2.6 2 0 0 2 2 2 2 CBS domain FixP_N PF14715.1 EPS32328.1 - 0.13 11.6 0.0 0.13 11.6 0.0 3.1 3 0 0 3 3 3 0 N-terminal domain of cytochrome oxidase-cbb3, FixP EamA PF00892.15 EPS32329.1 - 1.1e-05 25.4 12.2 4.4e-05 23.5 8.7 1.7 1 1 1 2 2 2 1 EamA-like transporter family EmrE PF13536.1 EPS32329.1 - 0.0012 19.0 5.4 0.0012 19.0 3.8 1.9 1 1 1 2 2 2 1 Multidrug resistance efflux transporter UPF0546 PF10639.4 EPS32329.1 - 0.008 15.9 1.3 0.01 15.6 0.9 1.3 1 0 0 1 1 1 1 Uncharacterised protein family UPF0546 PNPOx_C PF10590.4 EPS32330.1 - 2.3e-20 71.8 5.7 2.9e-20 71.4 2.5 2.2 2 0 0 2 2 2 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 EPS32330.1 - 3.3e-07 30.2 0.1 0.007 16.3 0.0 2.7 3 0 0 3 3 3 2 Pyridoxamine 5'-phosphate oxidase Gag_spuma PF03276.9 EPS32331.1 - 1.2 7.3 6.0 1.3 7.2 4.2 1.0 1 0 0 1 1 1 0 Spumavirus gag protein DJ-1_PfpI PF01965.19 EPS32332.1 - 5.3e-24 84.3 0.0 8.8e-24 83.6 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EPS32332.1 - 2.4e-05 23.7 0.0 7.7e-05 22.1 0.0 1.9 1 1 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family Glyco_trans_4_4 PF13579.1 EPS32332.1 - 0.039 14.0 0.0 0.11 12.6 0.0 1.7 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain PPR_2 PF13041.1 EPS32333.1 - 2.8e-48 161.6 4.7 6.9e-10 38.7 0.0 13.2 11 4 5 16 16 16 9 PPR repeat family PPR_3 PF13812.1 EPS32333.1 - 1e-28 97.1 26.4 0.0017 18.4 0.0 15.3 15 0 0 15 15 15 6 Pentatricopeptide repeat domain PPR PF01535.15 EPS32333.1 - 2e-24 83.8 15.5 0.00042 20.0 0.0 13.3 14 1 0 14 14 14 5 PPR repeat PPR_1 PF12854.2 EPS32333.1 - 2.1e-23 81.4 0.1 1.3e-06 27.7 0.0 9.7 10 1 0 10 10 10 5 PPR repeat RPM2 PF08579.6 EPS32333.1 - 2.8e-07 30.6 0.0 0.00048 20.2 0.0 4.3 4 0 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) ECSIT PF06239.6 EPS32333.1 - 0.0051 15.7 0.0 12 4.6 0.0 4.0 3 1 1 4 4 4 1 Evolutionarily conserved signalling intermediate in Toll pathway TPR_7 PF13176.1 EPS32333.1 - 0.22 11.4 5.4 6.5 6.8 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat GHMP_kinases_N PF00288.21 EPS32335.1 - 4.3e-14 52.3 3.5 9.2e-14 51.2 2.4 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EPS32335.1 - 1.2e-07 31.7 0.0 3.4e-07 30.3 0.0 1.8 1 1 0 1 1 1 1 GHMP kinases C terminal Rad60-SLD_2 PF13881.1 EPS32336.1 - 7.7e-12 45.0 0.0 1.5e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EPS32336.1 - 0.003 16.9 0.0 0.0073 15.6 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 EPS32336.1 - 0.0044 17.1 0.0 0.0091 16.1 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain UMP1 PF05348.6 EPS32337.1 - 2.1e-22 79.4 0.0 2.8e-22 79.0 0.0 1.3 1 1 0 1 1 1 1 Proteasome maturation factor UMP1 Ribosom_S12_S23 PF00164.20 EPS32338.1 - 1.9e-39 133.8 2.7 2.8e-39 133.3 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Glyco_transf_15 PF01793.11 EPS32339.1 - 6.7e-139 462.4 11.5 8.1e-139 462.1 7.9 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PAT1 PF09770.4 EPS32340.1 - 1.8e-272 906.3 18.6 1e-218 728.5 0.0 2.0 1 1 1 2 2 2 2 Topoisomerase II-associated protein PAT1 Epimerase PF01370.16 EPS32342.1 - 5.2e-47 160.2 0.0 6.9e-47 159.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EPS32342.1 - 5.1e-26 90.3 0.2 9.3e-26 89.5 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 EPS32342.1 - 9.7e-18 63.8 0.0 1.5e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EPS32342.1 - 1.6e-12 46.9 0.1 1.9e-11 43.3 0.1 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EPS32342.1 - 2.5e-12 46.3 0.1 3.6e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EPS32342.1 - 3e-11 43.5 0.0 5.3e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EPS32342.1 - 3.5e-10 40.1 0.0 5.4e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EPS32342.1 - 1.1e-08 34.9 0.0 1.9e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 EPS32342.1 - 1.4e-08 33.9 0.0 3.4e-08 32.7 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EPS32342.1 - 0.0019 17.4 0.0 0.0091 15.2 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family adh_short_C2 PF13561.1 EPS32342.1 - 0.0032 17.2 0.0 0.0048 16.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Phage_lysozyme PF00959.14 EPS32342.1 - 0.04 14.1 0.2 0.86 9.9 0.0 2.3 2 0 0 2 2 2 0 Phage lysozyme UDPG_MGDP_dh_N PF03721.9 EPS32342.1 - 0.045 13.1 0.1 0.077 12.3 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Cys_Met_Meta_PP PF01053.15 EPS32342.1 - 0.08 11.2 0.2 0.15 10.3 0.0 1.5 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme 3HCDH_N PF02737.13 EPS32342.1 - 0.081 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.20 EPS32343.1 - 1.2e-14 54.5 0.1 1.2e-13 51.3 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EPS32343.1 - 6.1e-09 35.7 0.0 1.3e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPS32343.1 - 0.00031 20.2 0.0 0.00051 19.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EPS32343.1 - 0.00092 19.2 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 EPS32343.1 - 0.0084 15.8 0.0 0.014 15.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 EPS32343.1 - 0.02 14.1 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family G-patch PF01585.18 EPS32344.1 - 9.1e-06 25.3 0.5 1.7e-05 24.4 0.3 1.4 1 0 0 1 1 1 1 G-patch domain His_Phos_1 PF00300.17 EPS32345.1 - 2.2e-30 105.8 0.6 2.6e-30 105.6 0.4 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF3772 PF12607.3 EPS32345.1 - 0.1 12.2 0.1 0.23 11.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3772) HA2 PF04408.18 EPS32346.1 - 6.4e-29 99.9 0.1 1.6e-28 98.6 0.1 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EPS32346.1 - 9.1e-28 96.3 0.0 7.8e-27 93.3 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EPS32346.1 - 6.3e-13 48.3 0.0 1.6e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 EPS32346.1 - 5.6e-10 39.1 0.7 1.2e-09 38.0 0.5 1.5 1 0 0 1 1 1 1 S1 RNA binding domain DEAD PF00270.24 EPS32346.1 - 2.7e-06 27.0 0.0 5.6e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 EPS32346.1 - 0.00019 20.4 0.0 0.00045 19.1 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 EPS32346.1 - 0.00026 21.1 0.0 0.00073 19.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPS32346.1 - 0.0095 15.6 0.2 0.026 14.2 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EPS32346.1 - 0.02 14.5 0.0 0.07 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EPS32346.1 - 0.069 13.0 0.3 0.92 9.3 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EPS32346.1 - 0.13 12.5 0.0 0.4 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EPS32346.1 - 0.14 12.0 0.2 1.3 8.9 0.1 2.4 1 1 0 1 1 1 0 AAA domain SUV3_C PF12513.3 EPS32347.1 - 2.2e-14 52.6 0.1 4.5e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 EPS32347.1 - 3.1e-09 36.5 0.0 1e-08 34.9 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Sec1 PF00995.18 EPS32348.1 - 1.1e-133 446.8 0.0 1.4e-133 446.5 0.0 1.1 1 0 0 1 1 1 1 Sec1 family Npa1 PF11707.3 EPS32349.1 - 7.2e-98 327.6 0.6 6.2e-97 324.5 0.0 2.5 3 0 0 3 3 3 1 Ribosome 60S biogenesis N-terminal PqqD PF05402.7 EPS32349.1 - 0.041 13.8 0.8 0.15 12.0 0.2 2.3 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) oligo_HPY PF08352.7 EPS32352.1 - 0.05 13.9 0.2 0.17 12.2 0.2 1.9 1 1 0 1 1 1 0 Oligopeptide/dipeptide transporter, C-terminal region CM_1 PF07736.6 EPS32352.1 - 0.089 12.8 0.3 0.16 12.0 0.2 1.3 1 0 0 1 1 1 0 Chorismate mutase type I UCH PF00443.24 EPS32354.1 - 7.9e-40 136.6 0.0 1.1e-39 136.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPS32354.1 - 1.2e-09 38.0 0.0 2.6e-09 36.9 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF918 PF06033.6 EPS32354.1 - 0.0042 16.6 0.0 0.0081 15.7 0.0 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF918) Cortex-I_coil PF09304.5 EPS32354.1 - 0.052 13.5 1.0 2.7 8.0 0.2 2.7 1 1 0 2 2 2 0 Cortexillin I, coiled coil Pantoate_transf PF02548.10 EPS32354.1 - 0.1 11.6 0.0 0.24 10.4 0.0 1.5 2 0 0 2 2 2 0 Ketopantoate hydroxymethyltransferase DUF515 PF04415.7 EPS32354.1 - 3.1 5.9 6.6 4.9 5.2 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Alb1 PF09135.6 EPS32355.1 - 2.8e-27 95.5 16.7 4.8e-27 94.7 11.6 1.3 1 0 0 1 1 1 1 Alb1 Atg14 PF10186.4 EPS32355.1 - 3.8 6.3 8.8 4.5 6.1 6.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Vps16_N PF04841.8 EPS32356.1 - 2.7e-96 322.6 0.0 3.5e-96 322.2 0.0 1.1 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 EPS32356.1 - 9.2e-82 274.5 0.2 1.3e-81 274.0 0.1 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region Bestrophin PF01062.16 EPS32358.1 - 6e-41 140.2 0.0 5e-40 137.2 0.0 2.2 1 1 1 2 2 2 1 Bestrophin, RFP-TM, chloride channel FHA PF00498.21 EPS32359.1 - 2.7e-14 53.0 0.1 5.2e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 EPS32359.1 - 1.8e-06 27.6 9.1 3.2e-06 26.8 6.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EPS32359.1 - 0.0012 18.9 5.6 0.0022 18.0 3.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EPS32359.1 - 0.0033 17.1 6.1 0.006 16.2 4.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EPS32359.1 - 0.022 14.3 7.4 0.046 13.3 5.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPS32359.1 - 0.023 14.6 9.3 0.042 13.8 6.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EPS32359.1 - 0.053 13.3 3.0 0.1 12.4 2.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.6 EPS32359.1 - 0.3 11.1 5.6 0.64 10.0 3.9 1.6 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.1 EPS32359.1 - 0.78 9.6 7.0 1.5 8.7 4.5 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Arm PF00514.18 EPS32360.1 - 2.9e-67 220.3 29.7 1.1e-12 47.2 0.1 11.3 11 1 1 12 12 12 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EPS32360.1 - 1.5e-22 79.6 13.7 9e-06 25.8 0.1 7.3 2 2 2 6 6 6 5 HEAT repeats HEAT PF02985.17 EPS32360.1 - 1.1e-19 68.6 13.3 0.054 13.5 0.0 9.8 10 0 0 10 10 10 5 HEAT repeat HEAT_EZ PF13513.1 EPS32360.1 - 5.4e-15 55.3 10.7 0.0094 16.4 0.0 8.5 6 2 3 9 9 9 6 HEAT-like repeat Arm_2 PF04826.8 EPS32360.1 - 1.5e-10 40.6 8.4 0.0025 16.9 0.1 3.4 1 1 2 3 3 3 3 Armadillo-like Adaptin_N PF01602.15 EPS32360.1 - 2.2e-10 39.5 8.3 1.1e-06 27.2 0.6 3.0 1 1 1 2 2 2 2 Adaptin N terminal region KAP PF05804.7 EPS32360.1 - 4.3e-10 38.2 1.0 7.6e-10 37.3 0.7 1.4 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) V-ATPase_H_N PF03224.9 EPS32360.1 - 4.4e-08 32.6 2.1 0.0053 15.9 0.0 3.4 2 1 1 3 3 3 2 V-ATPase subunit H Vac14_Fab1_bd PF12755.2 EPS32360.1 - 0.0096 16.2 0.1 4 7.8 0.1 3.7 2 1 2 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_PBS PF03130.11 EPS32360.1 - 0.01 16.2 4.9 21 5.9 0.2 6.1 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat Atx10homo_assoc PF09759.4 EPS32360.1 - 0.58 9.9 2.7 11 5.8 0.0 3.8 6 0 0 6 6 6 0 Spinocerebellar ataxia type 10 protein domain EXOSC1 PF10447.4 EPS32361.1 - 7.8e-28 96.2 0.4 1.3e-27 95.5 0.3 1.4 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 EPS32361.1 - 1.2e-15 56.4 0.3 2.1e-15 55.7 0.2 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region CRISPR_Cse2 PF09485.5 EPS32361.1 - 0.12 12.4 0.1 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) GTP_EFTU PF00009.22 EPS32362.1 - 7e-52 175.6 0.0 1.4e-51 174.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EPS32362.1 - 1.5e-15 56.8 0.0 3.9e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EPS32362.1 - 2.5e-07 30.4 0.0 5.6e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EPS32362.1 - 2.7e-07 30.5 0.0 9.6e-07 28.8 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 EPS32362.1 - 0.00013 21.5 0.1 0.057 12.9 0.0 3.0 3 0 0 3 3 3 2 Elongation factor G, domain IV SET PF00856.23 EPS32362.1 - 0.062 13.6 0.3 0.66 10.2 0.0 2.3 2 0 0 2 2 2 0 SET domain DUF4604 PF15377.1 EPS32363.1 - 3.7e-23 82.4 12.1 4.2e-23 82.2 8.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) DEC-1_C PF04626.8 EPS32363.1 - 0.13 12.4 0.8 0.48 10.5 0.1 2.1 1 1 1 2 2 2 0 Dec-1 protein, C terminal region Prp19 PF08606.6 EPS32364.1 - 9.1e-32 108.6 2.1 1.5e-31 107.9 1.4 1.3 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 EPS32364.1 - 4.4e-20 70.7 0.6 0.0011 18.7 0.0 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EPS32364.1 - 3.8e-09 35.8 0.0 0.00015 20.6 0.0 2.2 1 1 1 2 2 2 2 Coatomer WD associated region eIF2A PF08662.6 EPS32364.1 - 3.8e-05 23.4 0.2 0.0018 18.0 0.1 2.4 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A DUF3312 PF11768.3 EPS32364.1 - 0.0024 16.1 0.0 0.12 10.6 0.0 2.2 1 1 2 3 3 3 1 Protein of unknown function (DUF3312) U-box PF04564.10 EPS32364.1 - 0.0041 17.0 0.0 0.0091 15.9 0.0 1.6 1 0 0 1 1 1 1 U-box domain Cytochrom_D1 PF02239.11 EPS32364.1 - 0.011 14.0 0.4 0.083 11.1 0.4 2.3 2 1 1 3 3 3 0 Cytochrome D1 heme domain IceA2 PF05862.6 EPS32364.1 - 0.052 13.2 0.9 17 5.2 0.5 2.7 2 0 0 2 2 2 0 Helicobacter pylori IceA2 protein DXP_redisom_C PF08436.7 EPS32364.1 - 0.1 12.4 0.0 1.1 9.1 0.0 2.4 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal zf-Nse PF11789.3 EPS32364.1 - 0.15 11.6 0.0 0.3 10.6 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_2 PF13923.1 EPS32365.1 - 0.00033 20.6 1.0 0.00033 20.6 0.7 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPS32365.1 - 0.0023 17.6 3.4 0.0038 16.9 2.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain FYVE PF01363.16 EPS32365.1 - 0.079 12.8 2.7 0.17 11.8 1.9 1.6 1 1 0 1 1 1 0 FYVE zinc finger zf-C3HC4 PF00097.20 EPS32365.1 - 0.14 11.8 3.8 0.62 9.7 3.0 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPS32365.1 - 0.14 11.9 3.2 0.34 10.7 2.2 1.6 1 1 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.1 EPS32365.1 - 0.16 11.8 0.2 0.16 11.8 0.1 1.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING L51_S25_CI-B8 PF05047.11 EPS32366.1 - 3.6e-17 61.8 0.2 6.7e-17 60.9 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain U1snRNP70_N PF12220.3 EPS32367.1 - 8.2e-33 112.5 1.8 1.3e-32 111.9 1.3 1.4 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 EPS32367.1 - 2.8e-16 58.9 0.0 4.6e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS32367.1 - 1.9e-10 40.5 0.0 2.8e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS32367.1 - 2.3e-07 30.5 0.0 4.1e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L10 PF00466.15 EPS32368.1 - 4e-17 61.9 0.0 1.1e-16 60.5 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L10 7TMR-HDED PF07697.6 EPS32368.1 - 0.096 12.4 0.1 0.31 10.7 0.0 1.8 2 0 0 2 2 2 0 7TM-HD extracellular DUF3722 PF12519.3 EPS32369.1 - 9.7e-85 283.9 1.9 1.6e-84 283.1 1.3 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3722) TIM PF00121.13 EPS32370.1 - 1.2e-90 302.8 0.4 1.3e-90 302.7 0.3 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase DeoRC PF00455.17 EPS32370.1 - 0.0066 16.1 0.2 1.5 8.4 0.1 2.7 2 1 1 3 3 3 2 DeoR C terminal sensor domain Dak1_2 PF13684.1 EPS32370.1 - 0.02 13.8 0.7 0.08 11.8 0.2 1.8 1 1 1 2 2 2 0 Dihydroxyacetone kinase family TGT PF01702.13 EPS32370.1 - 0.042 13.1 0.0 0.092 12.0 0.0 1.5 1 1 0 1 1 1 0 Queuine tRNA-ribosyltransferase Snf7 PF03357.16 EPS32372.1 - 6.6e-37 126.5 17.3 2.4e-36 124.6 12.7 1.4 2 0 0 2 2 2 1 Snf7 V_ATPase_I PF01496.14 EPS32372.1 - 0.0049 14.7 3.1 0.0059 14.5 2.1 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Ist1 PF03398.9 EPS32372.1 - 0.038 13.3 5.5 0.056 12.8 3.8 1.3 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway DSBA PF01323.15 EPS32372.1 - 0.95 8.9 6.4 4.7 6.7 4.4 1.9 1 1 0 1 1 1 0 DSBA-like thioredoxin domain YlqD PF11068.3 EPS32372.1 - 2.4 8.1 16.8 3.2 7.8 7.2 2.2 1 1 1 2 2 2 0 YlqD protein TPR_MLP1_2 PF07926.7 EPS32372.1 - 2.7 7.7 12.3 6.5 6.5 8.4 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Pox_A_type_inc PF04508.7 EPS32372.1 - 7.5 6.6 9.1 0.85 9.5 2.7 2.3 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Dynamin_N PF00350.18 EPS32373.1 - 6.1e-17 61.9 0.5 1.4e-16 60.7 0.0 1.9 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 EPS32373.1 - 2.8e-09 36.9 0.0 1.4e-08 34.6 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EPS32373.1 - 1.6e-06 27.6 2.2 6.5e-06 25.6 0.2 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EPS32373.1 - 0.0068 16.9 0.1 0.71 10.3 0.0 3.0 2 1 0 2 2 2 1 Miro-like protein IIGP PF05049.8 EPS32373.1 - 0.023 13.5 0.0 0.047 12.5 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_18 PF13238.1 EPS32373.1 - 0.04 14.2 0.0 0.13 12.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EPS32373.1 - 0.064 12.8 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 EPS32373.1 - 0.088 13.6 2.1 0.6 10.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain Myosin_tail_1 PF01576.14 EPS32373.1 - 0.25 9.0 8.4 0.036 11.7 1.4 2.0 2 0 0 2 2 2 0 Myosin tail DUF883 PF05957.8 EPS32373.1 - 1.8 9.0 7.5 4.1 7.8 0.0 3.8 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) Glyco_hydro_43 PF04616.9 EPS32374.1 - 1.4e-61 208.0 2.9 1.8e-61 207.7 2.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 PTCB-BRCT PF12738.2 EPS32375.1 - 2.4e-49 165.0 0.1 1.2e-22 79.4 0.2 4.0 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.21 EPS32375.1 - 1.8e-30 104.8 0.1 6.4e-14 51.8 0.1 4.2 4 1 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain PIF1 PF05970.9 EPS32376.1 - 3.5e-64 217.0 0.1 1.9e-48 165.2 0.0 2.1 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EPS32376.1 - 3.6e-19 69.1 0.0 6.6e-19 68.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EPS32376.1 - 6e-08 32.9 0.0 1.5e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.1 EPS32376.1 - 2.2e-05 24.5 0.1 0.00025 21.1 0.1 2.5 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EPS32376.1 - 3.3e-05 23.5 0.1 7.8e-05 22.3 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain Herpes_Helicase PF02689.9 EPS32376.1 - 7.7e-05 20.6 0.1 0.00043 18.1 0.0 1.9 2 0 0 2 2 2 1 Helicase AAA PF00004.24 EPS32376.1 - 0.00043 20.4 0.0 0.00087 19.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EPS32376.1 - 0.0014 18.4 0.1 0.0045 16.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EPS32376.1 - 0.0019 18.3 0.0 0.0062 16.6 0.0 2.0 1 1 0 1 1 1 1 RNA helicase AAA_16 PF13191.1 EPS32376.1 - 0.0022 17.9 1.4 0.0072 16.3 0.0 2.5 4 0 0 4 4 4 1 AAA ATPase domain Viral_helicase1 PF01443.13 EPS32376.1 - 0.003 17.1 0.0 1.1 8.7 0.0 2.7 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 EPS32376.1 - 0.0031 16.5 0.0 0.0072 15.3 0.0 1.7 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) TrwB_AAD_bind PF10412.4 EPS32376.1 - 0.0093 14.6 0.1 0.02 13.5 0.0 1.4 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_10 PF12846.2 EPS32376.1 - 0.012 15.1 0.3 1.3 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain T2SE PF00437.15 EPS32376.1 - 0.015 14.2 0.0 0.028 13.3 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.11 EPS32376.1 - 0.016 14.4 0.0 0.24 10.6 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein Arch_ATPase PF01637.13 EPS32376.1 - 0.024 14.3 0.5 0.024 14.3 0.3 2.1 2 1 0 2 2 2 0 Archaeal ATPase AAA_5 PF07728.9 EPS32376.1 - 0.041 13.6 0.3 0.39 10.4 0.2 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) UvrD-helicase PF00580.16 EPS32376.1 - 0.044 13.0 0.0 0.044 13.0 0.0 1.6 2 0 0 2 2 1 0 UvrD/REP helicase N-terminal domain NACHT PF05729.7 EPS32376.1 - 0.045 13.4 0.0 0.085 12.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_25 PF13481.1 EPS32376.1 - 0.055 12.8 0.0 0.97 8.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EPS32376.1 - 0.059 13.6 0.2 0.29 11.4 0.0 2.1 1 1 0 2 2 2 0 ABC transporter AAA_11 PF13086.1 EPS32376.1 - 0.06 12.9 2.5 0.26 10.8 0.0 2.9 2 1 1 3 3 3 0 AAA domain MobB PF03205.9 EPS32376.1 - 0.099 12.3 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B YjeF_N PF03853.10 EPS32377.1 - 3e-40 137.5 0.2 4.4e-40 137.0 0.1 1.2 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 EPS32377.1 - 1.4e-09 38.4 0.4 2.8e-09 37.4 0.3 1.5 1 0 0 1 1 1 1 FDF domain Zn_clus PF00172.13 EPS32378.1 - 9.2e-09 35.0 7.1 9.2e-09 35.0 4.9 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EPS32378.1 - 0.0089 14.9 0.1 0.015 14.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pro_isomerase PF00160.16 EPS32379.1 - 1.6e-40 138.8 0.0 3e-40 137.9 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 EPS32379.1 - 1.1e-05 24.8 0.0 2.7e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 Rtf2 RING-finger U-box PF04564.10 EPS32379.1 - 0.0013 18.6 0.0 0.0071 16.2 0.0 2.1 1 1 1 2 2 2 1 U-box domain PP2C PF00481.16 EPS32380.1 - 5.4e-64 216.0 0.3 4.4e-52 177.0 0.3 3.0 1 1 1 2 2 2 2 Protein phosphatase 2C DUF4581 PF15167.1 EPS32380.1 - 0.087 12.7 0.0 11 5.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4581) Mhr1 PF12829.2 EPS32381.1 - 1.7e-29 101.4 0.1 1.7e-29 101.4 0.1 1.7 2 0 0 2 2 2 1 Transcriptional regulation of mitochondrial recombination Pox_A_type_inc PF04508.7 EPS32381.1 - 0.076 12.8 0.5 0.51 10.2 0.3 2.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Atg14 PF10186.4 EPS32382.1 - 6.6e-24 84.3 1.0 9.6e-24 83.8 0.7 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 EPS32382.1 - 0.00065 18.8 3.7 0.0023 17.0 2.6 1.8 1 1 0 1 1 1 1 Autophagy protein Apg6 DUF507 PF04368.8 EPS32382.1 - 0.012 15.2 0.8 0.021 14.4 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF507) Spc7 PF08317.6 EPS32382.1 - 0.55 8.8 9.5 0.93 8.0 6.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Zn_clus PF00172.13 EPS32383.1 - 4.7e-07 29.6 14.8 7e-07 29.0 10.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Asp PF00026.18 EPS32384.1 - 1.5e-71 241.2 9.4 1.8e-71 240.9 6.5 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EPS32384.1 - 6.2e-06 26.6 2.2 0.0016 18.8 0.3 3.2 3 1 0 3 3 3 2 Aspartyl protease TAXi_N PF14543.1 EPS32384.1 - 0.00013 21.9 0.9 0.00033 20.6 0.6 1.7 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EPS32384.1 - 0.045 13.3 0.0 0.15 11.6 0.0 1.9 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal PalH PF08733.5 EPS32385.1 - 4.6e-103 344.7 0.0 5.6e-102 341.1 0.0 2.0 1 1 0 1 1 1 1 PalH/RIM21 MFS_1 PF07690.11 EPS32386.1 - 1.8e-43 148.6 19.9 3.2e-36 124.7 7.9 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EPS32386.1 - 2e-09 36.3 15.8 6.4e-06 24.8 1.6 3.1 3 0 0 3 3 3 3 MFS/sugar transport protein Adipogenin PF15202.1 EPS32386.1 - 0.077 12.8 0.2 3.3 7.6 0.0 2.5 2 0 0 2 2 2 0 Adipogenin F-box-like PF12937.2 EPS32387.1 - 2.9e-07 30.1 0.1 6.2e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 F-box-like PhyH PF05721.8 EPS32388.1 - 7.7e-11 42.4 0.0 1.2e-10 41.7 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 EPS32388.1 - 2.1e-08 33.0 0.1 0.00013 20.6 0.0 3.0 2 1 0 2 2 2 2 Protein of unknown function (DUF1479) DIOX_N PF14226.1 EPS32389.1 - 2.6e-34 118.2 0.0 4.3e-34 117.5 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EPS32389.1 - 1.4e-18 67.0 0.0 2.4e-18 66.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPT PF03151.11 EPS32390.1 - 4.8e-30 104.2 8.9 4.8e-30 104.2 6.1 2.8 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EPS32390.1 - 6.4e-06 25.3 20.1 6.5e-05 22.0 13.9 2.1 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EPS32390.1 - 0.0023 17.9 31.4 0.0026 17.7 3.7 2.9 3 0 0 3 3 3 2 EamA-like transporter family DUF883 PF05957.8 EPS32390.1 - 0.13 12.6 0.1 0.24 11.8 0.1 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Dabb PF07876.7 EPS32391.1 - 1.7e-22 79.6 0.0 2.1e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain MscL PF01741.13 EPS32392.1 - 5e-14 52.5 0.7 1.3e-13 51.2 0.5 1.6 1 1 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL C1_1 PF00130.17 EPS32392.1 - 0.0063 16.2 1.4 0.01 15.5 1.0 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) UPF0547 PF10571.4 EPS32392.1 - 0.25 11.0 2.8 0.44 10.2 1.9 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 DUF1435 PF07256.7 EPS32393.1 - 2.6 8.0 0.0 2.6 8.0 0.0 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1435) PLAC8 PF04749.12 EPS32394.1 - 4.2e-22 78.6 19.3 5.7e-22 78.2 13.4 1.2 1 0 0 1 1 1 1 PLAC8 family IPK PF03770.11 EPS32396.1 - 7.6e-57 192.1 0.0 1.3e-56 191.3 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase Pam17 PF08566.5 EPS32396.1 - 0.022 14.4 0.0 0.047 13.3 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial import protein Pam17 MFS_1 PF07690.11 EPS32397.1 - 1.5e-22 79.8 9.1 3.1e-22 78.7 6.3 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Nodulin-like PF06813.8 EPS32397.1 - 3.2e-07 29.8 3.8 3.2e-07 29.8 2.6 2.1 2 0 0 2 2 2 2 Nodulin-like TarH PF02203.10 EPS32397.1 - 0.49 10.2 1.5 2.1 8.1 0.0 2.4 3 0 0 3 3 3 0 Tar ligand binding domain homologue ERCC4 PF02732.10 EPS32398.1 - 9.3e-24 83.8 0.2 4e-23 81.7 0.0 2.0 2 0 0 2 2 2 1 ERCC4 domain Ycf1 PF05758.7 EPS32398.1 - 0.74 7.4 8.0 1 6.9 5.5 1.1 1 0 0 1 1 1 0 Ycf1 Glycos_transf_1 PF00534.15 EPS32399.1 - 1.1e-29 103.0 0.2 5.1e-28 97.6 0.2 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EPS32399.1 - 4.8e-12 45.9 0.0 3.6e-10 39.8 0.0 2.3 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 EPS32399.1 - 8.7e-08 32.4 0.1 5.9e-05 23.2 0.0 3.3 2 1 1 3 3 3 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EPS32399.1 - 2.7e-07 30.8 0.1 8.4e-07 29.2 0.1 2.0 1 1 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EPS32399.1 - 4.4e-05 23.6 0.0 9.7e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Kinesin PF00225.18 EPS32400.1 - 3.7e-91 305.3 0.0 3.7e-91 305.3 0.0 2.5 2 0 0 2 2 2 1 Kinesin motor domain Arginase PF00491.16 EPS32401.1 - 3.7e-88 295.4 0.0 4.6e-88 295.1 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EPS32401.1 - 0.057 13.6 0.1 0.11 12.7 0.0 1.5 1 1 0 1 1 1 0 UPF0489 domain MFS_1 PF07690.11 EPS32402.1 - 1.9e-35 122.2 41.9 9.4e-32 110.0 21.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS32402.1 - 3.3e-11 42.4 4.9 3.3e-11 42.4 3.4 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter GP41 PF00517.12 EPS32402.1 - 0.1 12.1 0.0 3.4 7.1 0.0 2.4 2 0 0 2 2 2 0 Retroviral envelope protein MatE PF01554.13 EPS32403.1 - 5.8e-52 175.5 22.0 3.2e-31 108.1 2.5 2.3 2 0 0 2 2 2 2 MatE CRAL_TRIO PF00650.15 EPS32404.1 - 6.7e-39 132.9 0.0 9.3e-39 132.4 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EPS32404.1 - 4e-11 42.8 0.2 1.1e-10 41.4 0.1 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EPS32404.1 - 0.00034 20.5 0.0 0.00049 20.0 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Pol_alpha_B_N PF08418.5 EPS32405.1 - 2.2e-63 214.1 0.0 2.9e-63 213.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 EPS32405.1 - 2.3e-36 125.0 0.0 3.2e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Apc13p PF05839.6 EPS32406.1 - 9.6e-21 73.5 0.0 4.9e-15 55.2 0.0 2.1 2 0 0 2 2 2 2 Apc13p protein IF-2B PF01008.12 EPS32407.1 - 7.8e-75 251.4 0.4 9.6e-75 251.1 0.3 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Kinesin PF00225.18 EPS32408.1 - 4.5e-113 377.3 0.0 7.2e-113 376.6 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain V_ATPase_I PF01496.14 EPS32408.1 - 0.035 11.9 5.6 0.053 11.3 3.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1460 PF07313.7 EPS32408.1 - 0.14 11.3 2.3 0.24 10.5 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) DUF87 PF01935.12 EPS32408.1 - 5.5 6.7 8.2 0.73 9.6 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function DUF87 EndoU_bacteria PF14436.1 EPS32409.1 - 0.023 14.5 0.4 0.028 14.2 0.3 1.2 1 0 0 1 1 1 0 Bacterial EndoU nuclease Macro_2 PF14519.1 EPS32410.1 - 0.0075 15.4 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Macro-like domain Ion_trans_2 PF07885.11 EPS32411.1 - 5.1e-29 99.8 31.0 5.5e-17 61.2 5.2 3.8 4 0 0 4 4 4 2 Ion channel Ion_trans PF00520.26 EPS32411.1 - 0.053 12.7 18.3 0.16 11.1 0.5 3.8 3 1 0 3 3 3 0 Ion transport protein AMP-binding PF00501.23 EPS32413.1 - 8.5e-83 278.0 0.0 1.7e-82 277.0 0.0 1.5 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EPS32413.1 - 5.4e-64 215.5 0.0 1.4e-63 214.1 0.0 1.8 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EPS32413.1 - 1.8e-34 119.0 6.5 1.7e-31 109.4 2.3 3.1 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EPS32413.1 - 2.7e-19 69.5 2.8 2.7e-15 56.4 1.4 2.6 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 EPS32413.1 - 9.4e-18 64.8 1.7 2.4e-17 63.4 0.1 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EPS32413.1 - 1.5e-16 60.5 0.0 4.2e-10 39.4 0.0 2.8 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EPS32413.1 - 1.1e-11 44.7 0.0 3e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 EPS32413.1 - 7.8e-10 37.9 0.1 0.00016 20.4 0.0 3.3 3 0 0 3 3 3 3 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EPS32413.1 - 6.1e-07 28.6 0.5 8e-05 21.6 0.0 3.1 3 0 0 3 3 3 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EPS32413.1 - 1.7e-06 28.1 1.0 0.0094 15.9 0.2 3.8 3 2 0 3 3 2 2 NADH(P)-binding AMP-binding_C PF13193.1 EPS32413.1 - 1.5e-05 25.8 0.2 0.00041 21.2 0.0 3.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Polysacc_synt_2 PF02719.10 EPS32413.1 - 0.00095 18.1 1.4 1.9 7.3 0.1 3.2 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EPS32413.1 - 0.01 15.6 0.6 0.026 14.2 0.4 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 EPS32413.1 - 0.029 13.4 0.2 0.085 11.9 0.1 1.7 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DFP PF04127.10 EPS32413.1 - 0.19 11.3 0.8 0.47 10.0 0.4 1.7 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein NmrA PF05368.8 EPS32413.1 - 0.19 10.9 0.1 2 7.5 0.1 2.4 2 0 0 2 2 2 0 NmrA-like family Fungal_trans_2 PF11951.3 EPS32418.1 - 2.3e-51 174.6 0.0 7.5e-51 172.9 0.0 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS32418.1 - 1.9e-05 24.4 5.8 3.9e-05 23.4 4.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mannosyl_trans3 PF11051.3 EPS32421.1 - 7.6e-77 258.2 0.0 2e-76 256.9 0.0 1.6 1 1 0 1 1 1 1 Mannosyltransferase putative CWC25 PF12542.3 EPS32422.1 - 0.24 11.8 6.9 0.13 12.6 3.4 1.6 1 1 1 2 2 2 0 Pre-mRNA splicing factor DUF3340 PF11818.3 EPS32422.1 - 0.62 10.0 6.3 0.85 9.5 4.4 1.4 1 1 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) BCIP PF13862.1 EPS32424.1 - 1.2e-73 246.7 0.1 1.6e-73 246.4 0.1 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein DUF2435 PF10363.4 EPS32424.1 - 0.0069 16.2 0.1 0.068 13.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) CM_2 PF01817.16 EPS32425.1 - 5.3e-08 32.8 0.2 4.4e-05 23.4 0.0 3.3 3 1 0 3 3 3 2 Chorismate mutase type II WD40 PF00400.27 EPS32426.1 - 2.5e-37 125.4 9.9 5.3e-10 38.7 0.2 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EPS32426.1 - 1.8e-06 26.4 9.5 0.014 13.5 0.2 4.8 2 2 3 5 5 5 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EPS32426.1 - 0.0007 19.1 0.2 0.0039 16.6 0.0 2.1 1 1 0 2 2 2 1 PQQ-like domain APG6 PF04111.7 EPS32426.1 - 0.0095 15.0 2.5 0.015 14.3 1.7 1.3 1 0 0 1 1 1 1 Autophagy protein Apg6 IncA PF04156.9 EPS32426.1 - 0.73 9.4 3.7 1.3 8.5 2.6 1.4 1 0 0 1 1 1 0 IncA protein DUF1664 PF07889.7 EPS32426.1 - 0.95 9.2 3.1 1.4 8.7 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.17 EPS32426.1 - 6.3 6.8 9.0 3.6 7.6 4.8 1.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Sad1_UNC PF07738.8 EPS32427.1 - 2.4e-13 50.0 0.0 1.6e-07 31.1 0.0 2.3 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal SRR1 PF07985.7 EPS32428.1 - 0.00022 21.1 0.0 0.00093 19.0 0.0 2.1 2 0 0 2 2 2 1 SRR1 PCP_red PF08369.5 EPS32428.1 - 0.12 12.2 0.0 1.8 8.4 0.0 2.6 3 0 0 3 3 3 0 Proto-chlorophyllide reductase 57 kD subunit CBS PF00571.23 EPS32429.1 - 4.1e-27 93.7 3.8 2.6e-11 43.0 0.1 4.2 4 0 0 4 4 4 4 CBS domain HTH_9 PF08221.6 EPS32429.1 - 0.15 11.9 0.8 5.4 6.9 0.0 3.4 4 0 0 4 4 4 0 RNA polymerase III subunit RPC82 helix-turn-helix domain bZIP_1 PF00170.16 EPS32432.1 - 1.2e-12 47.5 11.8 2.7e-12 46.4 8.2 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EPS32432.1 - 5e-07 29.4 11.4 5e-07 29.4 7.9 2.2 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 EPS32432.1 - 0.0013 18.9 8.0 0.0013 18.9 5.5 2.2 2 0 0 2 2 2 1 bZIP Maf transcription factor Mnd1 PF03962.10 EPS32432.1 - 0.0061 16.2 5.9 0.0093 15.6 4.1 1.2 1 0 0 1 1 1 1 Mnd1 family MDFI PF15316.1 EPS32432.1 - 0.03 14.3 0.1 0.059 13.3 0.1 1.4 1 0 0 1 1 1 0 MyoD family inhibitor DUF349 PF03993.7 EPS32432.1 - 0.05 13.7 5.2 0.12 12.5 3.6 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) DUF342 PF03961.8 EPS32432.1 - 0.096 11.0 1.0 0.12 10.7 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Sulfatase PF00884.18 EPS32433.1 - 9.4e-73 245.0 0.0 1.2e-72 244.6 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 EPS32433.1 - 0.068 13.4 0.1 1.4 9.2 0.1 2.3 1 1 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF229 PF02995.12 EPS32433.1 - 0.16 10.3 0.0 0.24 9.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) ECH_C PF13766.1 EPS32434.1 - 6.2e-41 139.2 0.4 1.3e-40 138.2 0.3 1.5 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 EPS32434.1 - 3.9e-27 94.9 0.0 6.7e-26 90.9 0.0 2.0 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase family Ribosomal_L4 PF00573.17 EPS32435.1 - 1.1e-44 152.1 0.0 1.4e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family PBP PF01161.15 EPS32436.1 - 2.4e-10 40.4 0.0 3.8e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Peptidase_S24 PF00717.18 EPS32437.1 - 1.1e-05 24.9 0.0 2.2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EPS32437.1 - 0.00062 19.3 0.0 0.059 12.8 0.0 2.4 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 DUF1264 PF06884.6 EPS32438.1 - 1.8e-76 255.3 0.0 2.1e-76 255.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) NAD_kinase PF01513.16 EPS32442.1 - 2.7e-67 226.5 0.0 4.2e-67 225.9 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase TRAPP PF04051.11 EPS32444.1 - 1.2e-36 125.4 0.0 1.6e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Prp19_bind PF06991.6 EPS32445.1 - 3.3e-42 144.6 34.3 3.3e-42 144.6 23.8 2.4 1 1 0 2 2 2 1 Splicing factor, Prp19-binding domain Rep_fac-A_3 PF08661.6 EPS32446.1 - 1.9e-27 95.3 0.0 2.2e-27 95.0 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 GATA PF00320.22 EPS32447.1 - 3.1e-05 23.2 7.0 0.0015 17.7 1.5 2.5 2 0 0 2 2 2 2 GATA zinc finger LSM PF01423.17 EPS32448.1 - 7.4e-19 67.0 0.2 1e-18 66.6 0.2 1.2 1 0 0 1 1 1 1 LSM domain CAV_VP3 PF04771.7 EPS32448.1 - 0.038 13.9 0.0 0.094 12.6 0.0 1.5 1 1 1 2 2 2 0 Chicken anaemia virus VP-3 protein Dak1 PF02733.12 EPS32449.1 - 7.7e-109 363.1 0.1 1.2e-108 362.6 0.1 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EPS32449.1 - 1.8e-44 151.5 0.1 2.7e-44 150.9 0.1 1.3 1 0 0 1 1 1 1 DAK2 domain Cullin PF00888.17 EPS32450.1 - 1.9e-123 413.0 0.1 2.4e-123 412.7 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EPS32450.1 - 8.7e-25 86.3 3.8 1e-24 86.1 1.3 2.2 2 0 0 2 2 2 1 Cullin protein neddylation domain HTH_34 PF13601.1 EPS32450.1 - 0.03 14.3 0.1 0.32 11.0 0.0 2.3 2 0 0 2 2 2 0 Winged helix DNA-binding domain HbrB PF08539.6 EPS32450.1 - 0.063 13.1 0.1 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 HbrB-like DUF3414 PF11894.3 EPS32451.1 - 0 1446.9 25.1 0 1446.6 17.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) TAN PF11640.3 EPS32452.1 - 3.8e-46 156.6 0.7 2e-45 154.3 0.5 2.4 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair PI3_PI4_kinase PF00454.22 EPS32452.1 - 2.8e-44 151.3 0.0 5.8e-44 150.3 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EPS32452.1 - 1.4e-12 46.7 0.1 3.5e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 FATC domain UPF0052 PF01933.13 EPS32453.1 - 2.9e-53 181.1 0.0 3.8e-53 180.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 zf-RING_2 PF13639.1 EPS32454.1 - 5.7e-12 45.2 7.7 8.6e-12 44.6 5.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EPS32454.1 - 3.7e-11 42.8 7.1 6.3e-11 42.1 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPS32454.1 - 6.5e-11 41.7 6.4 9.5e-11 41.1 4.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPS32454.1 - 3.3e-10 39.4 7.4 5.5e-10 38.7 5.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EPS32454.1 - 3.8e-09 36.2 6.0 3e-08 33.3 4.5 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EPS32454.1 - 8.9e-09 34.9 7.9 1.4e-08 34.2 5.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EPS32454.1 - 8.7e-06 25.3 5.6 6.6e-05 22.5 1.3 2.4 2 0 0 2 2 2 1 RING-type zinc-finger FANCL_C PF11793.3 EPS32454.1 - 0.00028 20.7 6.1 0.0014 18.5 4.3 1.9 1 1 1 2 2 2 1 FANCL C-terminal domain Rad50_zn_hook PF04423.9 EPS32454.1 - 0.00095 18.5 0.3 0.14 11.6 0.1 2.4 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-Nse PF11789.3 EPS32454.1 - 0.00099 18.5 3.1 0.0019 17.7 2.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 EPS32454.1 - 0.003 17.0 4.8 0.0086 15.6 3.3 1.7 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain Tmpp129 PF10272.4 EPS32454.1 - 0.0048 15.6 2.0 0.0068 15.1 1.4 1.2 1 0 0 1 1 1 1 Putative transmembrane protein precursor zf-Apc11 PF12861.2 EPS32454.1 - 0.005 16.6 5.0 0.015 15.0 3.4 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-H2C2_2 PF13465.1 EPS32454.1 - 0.014 15.6 1.5 0.59 10.5 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger double domain zf-rbx1 PF12678.2 EPS32454.1 - 0.019 15.0 5.5 0.043 13.9 3.7 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger TerY-C PF15616.1 EPS32454.1 - 0.025 14.4 6.4 0.21 11.5 4.4 2.0 1 1 0 1 1 1 0 TerY-C metal binding domain DUF1644 PF07800.7 EPS32454.1 - 0.043 13.6 3.6 1.5 8.6 2.5 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) Zn_Tnp_IS91 PF14319.1 EPS32454.1 - 0.23 10.9 5.2 0.61 9.6 2.4 2.1 1 1 1 2 2 2 0 Transposase zinc-binding domain zf-RING_6 PF14835.1 EPS32454.1 - 0.27 11.0 6.9 1.4 8.7 4.8 2.1 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-Di19 PF05605.7 EPS32454.1 - 0.4 10.8 8.5 2.6 8.2 2.4 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-MIZ PF02891.15 EPS32454.1 - 0.47 10.0 9.2 1.7 8.2 6.4 1.9 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger zinc-ribbons_6 PF07191.7 EPS32454.1 - 0.56 10.0 7.1 2.7 7.8 2.0 2.3 1 1 0 2 2 2 0 zinc-ribbons FYVE PF01363.16 EPS32454.1 - 1 9.2 7.3 2.7 7.9 5.0 1.8 1 1 0 1 1 1 0 FYVE zinc finger DUF4379 PF14311.1 EPS32454.1 - 1.2 8.9 4.4 1.5 8.6 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4379) zf-CHY PF05495.7 EPS32454.1 - 2.5 8.3 7.7 5.5 7.2 5.3 1.5 1 1 0 1 1 1 0 CHY zinc finger Prok-RING_1 PF14446.1 EPS32454.1 - 2.5 7.8 8.1 2.7 7.7 0.1 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Prok-RING_4 PF14447.1 EPS32454.1 - 6.4 6.3 10.5 38 3.9 4.2 2.9 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 DZR PF12773.2 EPS32454.1 - 8.4 6.3 8.3 91 2.9 5.7 2.3 1 1 0 1 1 1 0 Double zinc ribbon IBR PF01485.16 EPS32454.1 - 9.5 6.1 10.1 18 5.2 0.1 2.7 1 1 1 2 2 2 0 IBR domain DNA_pol_A PF00476.15 EPS32455.1 - 1.5e-99 333.1 0.0 2.2e-99 332.6 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DUF1454 PF07305.7 EPS32455.1 - 0.11 11.6 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1454) Sugar_tr PF00083.19 EPS32456.1 - 1e-76 258.3 25.3 1.2e-76 258.1 17.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS32456.1 - 1.3e-15 56.9 29.7 1.3e-15 56.9 20.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily WHEP-TRS PF00458.15 EPS32456.1 - 0.11 12.1 0.1 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 WHEP-TRS domain GFO_IDH_MocA PF01408.17 EPS32458.1 - 1.1e-17 64.6 0.0 2e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EPS32458.1 - 8.4e-16 57.7 0.1 1.8e-15 56.7 0.1 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain CorA PF01544.13 EPS32459.1 - 1.4e-27 96.4 5.6 9.1e-19 67.5 0.9 3.2 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein SQS_PSY PF00494.14 EPS32460.1 - 2.5e-47 161.4 0.0 3.5e-47 160.9 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase SNF2_N PF00176.18 EPS32461.1 - 1.7e-69 233.8 0.0 2.3e-69 233.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 EPS32461.1 - 9.1e-21 73.7 0.0 1.9e-20 72.8 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 EPS32461.1 - 2.3e-13 49.7 0.0 7.8e-13 48.1 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 EPS32461.1 - 5e-06 26.4 12.8 1.1e-05 25.3 8.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPS32461.1 - 0.00013 21.5 9.7 0.00023 20.7 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPS32461.1 - 0.0019 17.8 11.8 0.0036 17.0 8.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EPS32461.1 - 0.0043 16.6 13.1 0.0083 15.7 9.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPS32461.1 - 0.0083 15.9 11.5 0.017 14.9 8.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EPS32461.1 - 0.5 10.2 11.3 1 9.3 7.8 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING GTP_EFTU PF00009.22 EPS32463.1 - 1.1e-21 77.0 0.0 1.2e-20 73.7 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EPS32463.1 - 9.6e-15 54.5 0.0 2e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EPS32463.1 - 3.5e-08 33.4 2.4 1.6e-07 31.3 1.3 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 PduV-EutP PF10662.4 EPS32463.1 - 0.0012 18.3 0.4 0.26 10.7 0.0 3.2 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EPS32463.1 - 0.014 15.8 0.1 0.15 12.5 0.0 2.7 2 1 0 2 2 2 0 Miro-like protein MMR_HSR1 PF01926.18 EPS32463.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase LSM PF01423.17 EPS32464.1 - 3.9e-18 64.7 0.3 5.7e-18 64.2 0.2 1.2 1 0 0 1 1 1 1 LSM domain SH3_9 PF14604.1 EPS32464.1 - 0.38 10.3 2.1 5.5 6.6 0.0 2.7 3 0 0 3 3 3 0 Variant SH3 domain ATP13 PF12921.2 EPS32465.1 - 2.2e-25 88.4 0.1 4.8e-25 87.3 0.1 1.6 1 0 0 1 1 1 1 Mitochondrial ATPase expression PPR_3 PF13812.1 EPS32465.1 - 0.0011 19.0 1.4 0.78 10.1 0.0 4.1 4 0 0 4 4 4 1 Pentatricopeptide repeat domain PPR_2 PF13041.1 EPS32465.1 - 0.0018 18.1 0.0 2.6 8.1 0.0 3.1 4 0 0 4 4 4 2 PPR repeat family RHH_2 PF03693.9 EPS32465.1 - 0.16 12.1 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0156) PIG-L PF02585.12 EPS32466.1 - 5.9e-28 97.9 0.0 9.7e-28 97.2 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase LDB19 PF13002.2 EPS32468.1 - 5.2e-59 198.9 0.0 9.1e-59 198.1 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.24 EPS32468.1 - 2.9e-08 33.6 0.0 2.1e-07 30.8 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain DUF4606 PF15379.1 EPS32468.1 - 0.1 12.6 0.4 0.21 11.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4606) GpcrRhopsn4 PF10192.4 EPS32472.1 - 0.015 14.4 5.2 0.034 13.3 3.6 1.4 1 0 0 1 1 1 0 Rhodopsin-like GPCR transmembrane domain DUF4579 PF15158.1 EPS32472.1 - 0.25 10.8 2.4 0.16 11.5 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4579) DUF2207 PF09972.4 EPS32472.1 - 0.67 8.4 5.8 0.44 9.0 2.5 1.8 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) AMP-binding PF00501.23 EPS32474.1 - 8.1e-75 251.7 0.0 1.1e-74 251.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPS32474.1 - 4.6e-15 56.3 0.4 1.4e-14 54.7 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain CN_hydrolase PF00795.17 EPS32475.1 - 6.9e-25 87.4 0.0 9.9e-25 86.9 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Gene66 PF02053.10 EPS32475.1 - 0.14 11.5 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Gene 66 (IR5) protein Ferritin_2 PF13668.1 EPS32477.1 - 8.5e-17 61.3 0.0 1.2e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain adh_short PF00106.20 EPS32478.1 - 1.5e-21 77.0 1.3 7.2e-15 55.3 0.5 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EPS32478.1 - 4.1e-15 56.2 0.0 2.9e-10 40.3 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPS32478.1 - 5.4e-11 42.4 1.7 9.9e-10 38.3 0.4 2.3 3 0 0 3 3 3 1 KR domain NAD_binding_10 PF13460.1 EPS32478.1 - 0.0053 16.7 0.5 0.0089 16.0 0.4 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EPS32478.1 - 0.0082 14.8 0.1 0.019 13.6 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EPS32478.1 - 0.023 13.5 0.0 0.039 12.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1776 PF08643.5 EPS32478.1 - 0.1 11.6 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DIOX_N PF14226.1 EPS32479.1 - 2e-24 86.3 0.0 3.8e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EPS32479.1 - 2.9e-19 69.2 0.1 8.4e-19 67.7 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily EthD PF07110.6 EPS32480.1 - 0.00037 21.3 0.0 0.001 19.9 0.0 1.6 1 1 0 1 1 1 1 EthD domain NAGLU PF05089.7 EPS32480.1 - 0.0067 15.2 0.0 0.0076 15.0 0.0 1.0 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain Amidohydro_2 PF04909.9 EPS32481.1 - 4.3e-36 124.8 1.9 6.4e-36 124.3 1.3 1.3 1 1 0 1 1 1 1 Amidohydrolase Mei4 PF13971.1 EPS32482.1 - 1.7e-05 24.0 0.2 2.7e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Meiosis-specific protein Mei4 Flagellar_rod PF05149.7 EPS32482.1 - 0.047 12.8 1.5 0.081 12.1 1.1 1.3 1 0 0 1 1 1 0 Paraflagellar rod protein DnaJ PF00226.26 EPS32483.1 - 1.5e-18 66.3 0.9 3.4e-18 65.1 0.7 1.7 1 0 0 1 1 1 1 DnaJ domain RRM_1 PF00076.17 EPS32483.1 - 0.028 14.0 0.0 0.17 11.5 0.0 2.3 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GCV_T PF01571.16 EPS32484.1 - 5e-13 48.9 0.0 1.9e-12 47.0 0.0 1.9 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EPS32484.1 - 1.2e-05 25.1 0.0 2.7e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain AFT PF08731.6 EPS32485.1 - 0.00017 21.7 3.0 0.058 13.5 0.0 3.1 2 2 0 2 2 2 2 Transcription factor AFT DBD_Tnp_Mut PF03108.10 EPS32485.1 - 0.00043 19.7 1.8 0.23 11.0 0.0 3.0 3 0 0 3 3 3 2 MuDR family transposase DCP2 PF05026.8 EPS32486.1 - 2.5e-36 123.4 1.4 4.8e-36 122.5 1.0 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 EPS32486.1 - 6.3e-16 58.2 0.0 1.2e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF4112 PF13430.1 EPS32487.1 - 2.2e-35 120.7 0.4 2.9e-35 120.3 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DUF2392 PF10288.4 EPS32488.1 - 1.8e-24 86.1 0.0 3.1e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) DUF1289 PF06945.8 EPS32488.1 - 0.011 15.2 0.3 0.19 11.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) FYVE PF01363.16 EPS32488.1 - 0.064 13.1 6.6 2.8 7.8 1.9 2.4 2 0 0 2 2 2 0 FYVE zinc finger zf-C3HC4_3 PF13920.1 EPS32488.1 - 3.7 7.2 7.9 4.9 6.9 1.6 2.9 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPS32488.1 - 8.9 6.4 10.3 2.8 8.0 1.4 3.0 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Lung_7-TM_R PF06814.8 EPS32489.1 - 4e-71 239.3 14.9 4.8e-71 239.1 10.3 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor PrgI PF12666.2 EPS32489.1 - 0.18 11.9 13.7 1.1 9.5 0.4 3.4 2 1 0 3 3 3 0 PrgI family protein DUF1308 PF07000.6 EPS32490.1 - 1.6e-93 313.2 0.0 2.3e-93 312.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) LEDGF PF11467.3 EPS32490.1 - 0.039 13.6 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 Lens epithelium-derived growth factor (LEDGF) Voldacs PF03517.8 EPS32490.1 - 0.1 12.4 1.4 0.17 11.7 0.0 2.0 2 0 0 2 2 2 0 Regulator of volume decrease after cellular swelling WD40 PF00400.27 EPS32491.1 - 6.6e-13 47.9 10.2 6.1e-09 35.4 0.5 5.4 6 1 0 6 6 6 2 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EPS32491.1 - 0.00056 18.3 0.8 0.11 10.8 0.1 3.4 2 2 0 3 3 3 2 Cytochrome D1 heme domain DUF4613 PF15390.1 EPS32491.1 - 0.043 12.0 0.3 0.099 10.8 0.1 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4613) Mito_carr PF00153.22 EPS32492.1 - 1.4e-58 194.5 3.3 7.5e-20 70.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PepSY_2 PF13670.1 EPS32493.1 - 0.16 11.9 0.3 0.16 11.9 0.2 2.4 2 1 0 2 2 2 0 Peptidase propeptide and YPEB domain Atrophin-1 PF03154.10 EPS32493.1 - 0.92 7.5 9.2 1.1 7.3 6.3 1.1 1 0 0 1 1 1 0 Atrophin-1 family DUF3759 PF12585.3 EPS32494.1 - 7.7e-29 99.4 1.4 8.9e-29 99.2 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) EF-1_beta_acid PF10587.4 EPS32494.1 - 0.047 13.8 0.0 0.047 13.8 0.0 2.4 3 0 0 3 3 3 0 Eukaryotic elongation factor 1 beta central acidic region Ran_BP1 PF00638.13 EPS32496.1 - 4.3e-50 168.8 2.0 1e-49 167.6 1.4 1.6 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 EPS32496.1 - 1.7e-06 27.7 0.4 1.2e-05 25.0 0.3 2.1 1 1 0 1 1 1 1 WH1 domain DUF4481 PF14800.1 EPS32496.1 - 0.087 11.7 0.1 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) DUF1681 PF07933.9 EPS32496.1 - 0.088 12.3 0.1 0.088 12.3 0.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1681) Pinin_SDK_N PF04697.8 EPS32496.1 - 0.48 10.4 3.7 0.66 10.0 1.5 2.0 1 1 1 2 2 2 0 pinin/SDK conserved region RAI1 PF08652.6 EPS32496.1 - 0.71 9.6 4.1 1.8 8.4 1.6 2.4 2 0 0 2 2 2 0 RAI1 like PD-(D/E)XK nuclease Dicty_REP PF05086.7 EPS32496.1 - 1.4 6.5 9.3 1.8 6.2 6.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Rep_3 PF01051.16 EPS32496.1 - 2.3 7.7 9.1 3.3 7.2 1.6 2.4 2 1 1 3 3 3 0 Initiator Replication protein YEATS PF03366.11 EPS32497.1 - 1.9e-18 65.9 0.1 3.4e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 YEATS family Phosducin PF02114.11 EPS32498.1 - 4.8e-11 41.8 0.0 2.9e-08 32.7 0.0 2.5 2 1 1 3 3 3 2 Phosducin WD40 PF00400.27 EPS32499.1 - 4.8e-53 175.2 21.4 4.3e-09 35.9 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EPS32499.1 - 4.2e-05 23.3 0.0 0.087 12.5 0.0 2.8 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A zf-MYND PF01753.13 EPS32501.1 - 9.6e-08 31.7 20.4 2.1e-07 30.6 14.2 1.6 1 0 0 1 1 1 1 MYND finger DIOX_N PF14226.1 EPS32502.1 - 6.4e-19 68.6 0.0 9.8e-19 68.0 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EPS32502.1 - 9.2e-12 45.1 0.0 1.8e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MKT1_C PF12246.3 EPS32503.1 - 8.2e-78 260.7 0.0 1.1e-77 260.2 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 EPS32503.1 - 1.3e-29 102.3 0.0 3.5e-29 100.9 0.0 1.8 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 EPS32503.1 - 1.7e-09 37.5 0.0 3.3e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EPS32503.1 - 0.00019 21.6 0.0 0.00055 20.1 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain Thioredoxin PF00085.15 EPS32504.1 - 1e-61 205.0 0.3 2.5e-30 104.2 0.0 2.6 3 0 0 3 3 3 2 Thioredoxin ERp29 PF07749.7 EPS32504.1 - 3e-23 82.2 0.3 6.9e-23 81.1 0.2 1.6 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 EPS32504.1 - 3.1e-21 75.6 0.2 2.4e-09 37.3 0.0 3.6 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EPS32504.1 - 1.2e-16 60.5 0.0 1.3e-08 34.6 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 EPS32504.1 - 1.4e-11 44.3 0.0 0.00069 19.6 0.0 4.0 3 1 1 4 4 4 2 Thioredoxin-like Thioredoxin_6 PF13848.1 EPS32504.1 - 2e-07 31.0 0.2 0.0031 17.3 0.0 3.0 2 1 0 2 2 2 2 Thioredoxin-like domain AhpC-TSA PF00578.16 EPS32504.1 - 8.7e-07 28.6 0.1 0.059 13.0 0.0 2.6 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 EPS32504.1 - 4e-06 26.4 0.2 0.1 12.1 0.0 2.5 2 0 0 2 2 2 2 Redoxin Thioredoxin_9 PF14595.1 EPS32504.1 - 0.0011 18.4 0.0 0.2 11.2 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_4 PF13462.1 EPS32504.1 - 0.0018 18.2 1.9 6.4 6.7 0.0 4.1 3 2 2 5 5 5 1 Thioredoxin Thioredoxin_3 PF13192.1 EPS32504.1 - 0.002 17.8 0.0 1.4 8.8 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin domain Glutaredoxin PF00462.19 EPS32504.1 - 0.01 15.7 0.1 9.2 6.3 0.1 3.0 2 1 0 2 2 2 0 Glutaredoxin TraF PF13728.1 EPS32504.1 - 0.051 13.0 0.0 2.4 7.6 0.0 2.3 2 0 0 2 2 2 0 F plasmid transfer operon protein HyaE PF07449.6 EPS32504.1 - 0.069 13.0 0.0 2.4 8.1 0.0 2.5 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE HSBP1 PF06825.7 EPS32505.1 - 6e-19 67.3 0.1 8.2e-19 66.9 0.1 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Matrilin_ccoil PF10393.4 EPS32505.1 - 0.00038 19.7 0.7 0.19 11.1 0.1 2.1 1 1 1 2 2 2 2 Trimeric coiled-coil oligomerisation domain of matrilin Baculo_PEP_C PF04513.7 EPS32505.1 - 0.0043 16.8 0.2 0.0052 16.6 0.1 1.1 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4164 PF13747.1 EPS32505.1 - 0.024 14.7 0.4 0.043 13.9 0.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4164) NPV_P10 PF05531.7 EPS32505.1 - 0.026 14.7 0.2 0.038 14.2 0.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF2937 PF11157.3 EPS32505.1 - 0.042 13.1 0.2 0.047 13.0 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Exonuc_VII_L PF02601.10 EPS32505.1 - 0.043 13.0 0.0 0.053 12.7 0.0 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit UPF0184 PF03670.8 EPS32505.1 - 0.069 13.3 1.3 0.11 12.6 0.9 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) WXG100 PF06013.7 EPS32505.1 - 0.077 12.9 0.6 0.11 12.4 0.4 1.2 1 0 0 1 1 1 0 Proteins of 100 residues with WXG DUF935 PF06074.7 EPS32505.1 - 0.2 10.3 1.6 0.22 10.2 1.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF935) Ebp2 PF05890.7 EPS32506.1 - 2.8e-90 302.3 22.1 2.8e-90 302.3 15.3 2.2 1 1 1 2 2 2 1 Eukaryotic rRNA processing protein EBP2 TFIIA PF03153.8 EPS32506.1 - 5.7 6.7 39.7 5.2 6.8 21.5 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TruB_N PF01509.13 EPS32507.1 - 6.9e-45 152.8 0.0 2.2e-44 151.2 0.0 1.7 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) MCPVI PF02993.9 EPS32507.1 - 0.7 10.0 7.9 1.5 8.9 5.5 1.5 1 0 0 1 1 1 0 Minor capsid protein VI DNMT1-RFD PF12047.3 EPS32508.1 - 0.062 12.9 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Cytosine specific DNA methyltransferase replication foci domain YniB PF14002.1 EPS32509.1 - 0.44 9.9 0.0 0.87 9.0 0.0 1.4 1 0 0 1 1 1 0 YniB-like protein OHCU_decarbox PF09349.5 EPS32510.1 - 1.3e-45 155.5 0.1 1.5e-45 155.3 0.1 1.0 1 0 0 1 1 1 1 OHCU decarboxylase WD40 PF00400.27 EPS32511.1 - 6.3e-33 111.4 13.7 2.1e-10 40.0 0.0 8.4 9 0 0 9 9 9 6 WD domain, G-beta repeat Nudix_N_2 PF14803.1 EPS32511.1 - 0.062 12.9 1.4 0.2 11.3 1.0 1.9 1 0 0 1 1 1 0 Nudix N-terminal BBS2_Mid PF14783.1 EPS32511.1 - 0.12 12.2 0.0 37 4.1 0.0 3.4 3 2 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region SRP9-21 PF05486.7 EPS32512.1 - 4.1e-27 93.7 0.8 6e-27 93.2 0.6 1.3 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Med3 PF11593.3 EPS32512.1 - 2.7 7.1 17.9 6.8 5.8 12.4 1.6 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal Ribonuc_red_sm PF00268.16 EPS32513.1 - 1.5e-120 401.4 0.7 1.8e-120 401.1 0.5 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain RE_XcyI PF09571.5 EPS32513.1 - 0.034 13.0 0.0 2.7 6.7 0.0 2.1 2 0 0 2 2 2 0 XcyI restriction endonuclease TMEM61 PF15105.1 EPS32514.1 - 0.052 13.0 0.2 0.06 12.8 0.1 1.1 1 0 0 1 1 1 0 TMEM61 protein family Cutinase PF01083.17 EPS32515.1 - 4.3e-51 173.1 0.2 4.9e-51 172.9 0.2 1.0 1 0 0 1 1 1 1 Cutinase VirJ PF06057.6 EPS32515.1 - 0.00022 21.0 0.0 0.00035 20.4 0.0 1.3 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) PE-PPE PF08237.6 EPS32515.1 - 0.0013 18.1 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_6 PF12697.2 EPS32515.1 - 0.042 13.7 0.0 0.067 13.0 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family PD40 PF07676.7 EPS32516.1 - 0.12 12.1 0.1 0.12 12.1 0.1 2.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat 2OG-FeII_Oxy PF03171.15 EPS32517.1 - 0.054 13.7 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Glyco_transf_15 PF01793.11 EPS32518.1 - 6.8e-132 439.4 2.9 8.4e-132 439.1 2.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase NUDIX PF00293.23 EPS32519.1 - 1.3e-12 47.5 0.1 2.5e-12 46.6 0.1 1.5 1 1 0 1 1 1 1 NUDIX domain PH PF00169.24 EPS32520.1 - 7.4e-27 93.5 0.0 4.5e-12 46.0 0.0 2.2 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 EPS32520.1 - 1.3e-12 47.9 0.2 9.9e-06 25.7 0.0 3.1 2 1 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.1 EPS32520.1 - 1.5e-09 38.0 0.3 8.7e-05 22.6 0.0 3.4 2 2 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.1 EPS32520.1 - 0.00012 21.8 0.1 0.25 11.2 0.0 2.3 2 0 0 2 2 2 2 PH domain Mcp5_PH PF12814.2 EPS32520.1 - 0.012 15.4 0.1 0.7 9.8 0.0 2.2 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology EamA PF00892.15 EPS32521.1 - 1.4e-08 34.8 34.8 5.6e-08 32.8 2.4 3.1 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.6 EPS32521.1 - 4.5e-06 25.8 12.4 7.9e-06 24.9 8.6 1.3 1 0 0 1 1 1 1 UAA transporter family EmrE PF13536.1 EPS32521.1 - 8e-06 26.0 6.8 8e-06 26.0 4.7 3.3 3 0 0 3 3 3 1 Multidrug resistance efflux transporter DUF914 PF06027.7 EPS32521.1 - 0.00096 18.0 9.6 0.00096 18.0 6.7 2.4 2 1 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) TPT PF03151.11 EPS32521.1 - 0.37 10.4 31.4 0.04 13.5 3.8 2.8 3 0 0 3 3 3 0 Triose-phosphate Transporter family Ras PF00071.17 EPS32522.1 - 1.7e-56 190.1 0.1 2e-56 189.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPS32522.1 - 1.9e-19 70.2 0.0 3e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPS32522.1 - 1.2e-12 47.4 0.0 1.4e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EPS32522.1 - 5.9e-07 29.4 0.0 8e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EPS32522.1 - 1.4e-06 27.9 0.0 2.6e-05 23.7 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EPS32522.1 - 3.1e-06 26.5 0.0 3.7e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EPS32522.1 - 0.00098 19.2 0.0 0.0021 18.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain cobW PF02492.14 EPS32522.1 - 0.001 18.5 0.0 0.012 15.1 0.0 2.0 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 EPS32522.1 - 0.0012 18.0 0.1 0.0025 16.9 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 EPS32522.1 - 0.0015 18.0 0.2 0.05 13.1 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 EPS32522.1 - 0.0045 16.4 0.1 0.13 11.7 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 EPS32522.1 - 0.005 16.4 0.1 0.0085 15.6 0.1 1.4 1 0 0 1 1 1 1 AAA domain Septin PF00735.13 EPS32522.1 - 0.0067 15.4 0.1 0.057 12.4 0.0 2.1 2 0 0 2 2 2 1 Septin Arch_ATPase PF01637.13 EPS32522.1 - 0.0082 15.8 0.6 0.014 15.1 0.0 1.6 2 0 0 2 2 2 1 Archaeal ATPase AAA_16 PF13191.1 EPS32522.1 - 0.0097 15.9 0.0 0.042 13.8 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 EPS32522.1 - 0.013 15.2 0.0 0.037 13.7 0.0 1.8 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 EPS32522.1 - 0.021 14.5 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 NTPase SRPRB PF09439.5 EPS32522.1 - 0.023 13.8 0.0 0.029 13.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_10 PF12846.2 EPS32522.1 - 0.025 13.9 0.3 0.058 12.8 0.1 1.6 2 0 0 2 2 2 0 AAA-like domain MobB PF03205.9 EPS32522.1 - 0.05 13.3 0.3 0.12 12.0 0.1 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EPS32522.1 - 0.067 12.8 0.1 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ATG16 PF08614.6 EPS32523.1 - 5e-47 160.2 19.4 5.9e-47 160.0 13.5 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF4201 PF13870.1 EPS32523.1 - 1.3e-06 27.9 10.3 2.1e-06 27.3 7.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4201) CCDC144C PF14915.1 EPS32523.1 - 4.9e-05 22.3 6.6 5.5e-05 22.2 4.6 1.2 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region MscS_porin PF12795.2 EPS32523.1 - 0.0015 17.8 18.5 0.0019 17.5 8.7 2.3 1 1 1 2 2 2 1 Mechanosensitive ion channel porin domain DUF4473 PF14747.1 EPS32523.1 - 0.0043 17.2 0.5 4 7.7 0.4 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4473) Syntaxin_2 PF14523.1 EPS32523.1 - 0.0043 17.0 5.5 0.01 15.8 3.8 1.7 1 1 0 1 1 1 1 Syntaxin-like protein Transposase_22 PF02994.9 EPS32523.1 - 0.0076 14.7 3.6 0.0088 14.5 2.5 1.2 1 0 0 1 1 1 1 L1 transposable element HAUS-augmin3 PF14932.1 EPS32523.1 - 0.0087 15.2 7.2 0.014 14.5 5.0 1.3 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 AAA_13 PF13166.1 EPS32523.1 - 0.016 13.6 2.9 0.018 13.5 2.0 1.1 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 EPS32523.1 - 0.024 13.6 9.8 0.037 13.0 6.8 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 GAS PF13851.1 EPS32523.1 - 0.076 12.1 16.5 0.1 11.7 9.9 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.7 EPS32523.1 - 0.089 12.6 3.1 1.4 8.7 2.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Nup54 PF13874.1 EPS32523.1 - 0.12 12.0 11.0 0.087 12.4 2.1 2.3 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 TPR_MLP1_2 PF07926.7 EPS32523.1 - 0.17 11.5 16.6 4.7 6.9 4.1 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.14 EPS32523.1 - 0.18 9.5 5.5 0.22 9.3 3.8 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 EPS32523.1 - 0.42 10.1 17.0 0.64 9.5 11.4 1.6 1 1 0 1 1 1 0 IncA protein Noelin-1 PF12308.3 EPS32523.1 - 0.42 10.4 5.0 0.37 10.5 2.4 1.8 1 1 1 2 2 2 0 Neurogenesis glycoprotein Snapin_Pallidin PF14712.1 EPS32523.1 - 0.56 10.5 6.3 0.41 10.9 0.5 2.5 1 1 1 2 2 2 0 Snapin/Pallidin GvpG PF05120.7 EPS32523.1 - 0.59 9.9 4.0 1.5 8.6 2.8 1.7 1 0 0 1 1 1 0 Gas vesicle protein G Scaffolding_pro PF11418.3 EPS32523.1 - 0.67 10.3 6.2 0.38 11.1 2.1 2.0 1 1 1 2 2 2 0 Phi29 scaffolding protein TBPIP PF07106.8 EPS32523.1 - 0.7 9.4 10.4 1.9 7.9 7.1 1.7 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) YlqD PF11068.3 EPS32523.1 - 0.78 9.7 6.1 1.4 8.9 4.2 1.5 1 0 0 1 1 1 0 YlqD protein DASH_Spc19 PF08287.6 EPS32523.1 - 0.81 9.2 0.1 0.81 9.2 0.0 2.4 1 1 1 2 2 2 0 Spc19 DUF342 PF03961.8 EPS32523.1 - 0.87 7.9 3.8 1.1 7.5 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Lge1 PF11488.3 EPS32523.1 - 1.1 9.4 10.9 8.3 6.6 2.9 2.8 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 DUF1319 PF07028.6 EPS32523.1 - 1.9 8.6 9.9 0.36 11.0 1.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) Cluap1 PF10234.4 EPS32523.1 - 2.7 7.1 13.3 12 5.0 9.0 1.8 1 1 0 1 1 1 0 Clusterin-associated protein-1 ADIP PF11559.3 EPS32523.1 - 2.9 7.7 17.9 1.9 8.3 5.4 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF972 PF06156.8 EPS32523.1 - 3.4 8.0 11.7 3.1 8.1 2.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Sec2p PF06428.6 EPS32523.1 - 3.9 7.3 14.2 1.9 8.4 7.6 2.2 2 1 0 2 2 2 0 GDP/GTP exchange factor Sec2p DivIC PF04977.10 EPS32523.1 - 5.7 6.5 11.3 5.8 6.4 0.6 2.7 1 1 2 3 3 3 0 Septum formation initiator CENP-Q PF13094.1 EPS32523.1 - 7.7 6.5 17.9 33 4.4 11.8 2.0 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4407 PF14362.1 EPS32523.1 - 8.5 5.2 10.2 12 4.7 7.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DOT1 PF08123.8 EPS32524.1 - 9.1e-78 260.2 0.3 2.1e-77 259.1 0.0 1.7 2 0 0 2 2 2 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 EPS32524.1 - 0.0002 21.3 0.0 0.00043 20.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPS32524.1 - 0.015 14.9 0.1 0.034 13.7 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EPS32524.1 - 0.041 14.4 0.1 0.11 13.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Spb1_C PF07780.7 EPS32525.1 - 9.6e-76 254.0 28.7 9.6e-76 254.0 19.9 4.7 2 1 2 4 4 4 1 Spb1 C-terminal domain DUF3381 PF11861.3 EPS32525.1 - 1.9e-55 186.7 9.9 1.9e-55 186.7 6.8 5.3 4 2 1 5 5 5 1 Domain of unknown function (DUF3381) FtsJ PF01728.14 EPS32525.1 - 2.2e-53 180.9 0.0 5e-53 179.7 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase Fungal_trans PF04082.13 EPS32527.1 - 2e-09 36.6 1.3 5.8e-09 35.2 0.9 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS32527.1 - 1.3e-07 31.4 7.3 1.3e-07 31.4 5.1 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EF-hand_4 PF12763.2 EPS32528.1 - 6.2e-06 25.9 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Fungal_trans PF04082.13 EPS32529.1 - 4.5e-20 71.6 2.1 1e-19 70.4 1.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS32529.1 - 4.7e-06 26.3 7.8 1.2e-05 25.1 5.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 EPS32529.1 - 7.8e-05 22.7 1.9 7.8e-05 22.7 1.3 3.6 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EPS32529.1 - 8.7e-05 22.6 2.6 8.7e-05 22.6 1.8 3.1 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EPS32529.1 - 0.012 15.8 1.8 0.012 15.8 1.2 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-met PF12874.2 EPS32529.1 - 0.024 14.8 0.3 0.024 14.8 0.2 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DNA_ligase_A_M PF01068.16 EPS32530.1 - 4.8e-48 163.2 0.0 2e-47 161.1 0.0 2.1 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EPS32530.1 - 4.4e-41 140.6 0.0 9.8e-41 139.5 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EPS32530.1 - 1.8e-17 63.5 0.2 1.5e-16 60.6 0.0 2.6 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 EPS32530.1 - 4.1e-07 30.0 0.1 2.2e-06 27.7 0.0 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain mRNA_cap_enzyme PF01331.14 EPS32530.1 - 0.078 12.6 0.0 8 6.1 0.0 3.6 3 1 0 3 3 3 0 mRNA capping enzyme, catalytic domain RNA_ligase PF09414.5 EPS32530.1 - 0.088 12.5 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 RNA ligase Fungal_trans PF04082.13 EPS32532.1 - 8.6e-39 132.9 0.1 1.6e-38 132.0 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS32532.1 - 7.5e-08 32.1 7.9 1.5e-07 31.1 5.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PHD PF00628.24 EPS32532.1 - 0.011 15.4 3.4 0.024 14.3 2.4 1.6 1 0 0 1 1 1 0 PHD-finger Metallophos PF00149.23 EPS32533.1 - 2.1e-36 125.2 0.3 2.2e-29 102.2 0.1 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase DUF3628 PF12300.3 EPS32534.1 - 0.0013 18.8 0.1 0.0019 18.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3628) NSP2-B_epitope PF14757.1 EPS32534.1 - 0.01 15.3 0.2 0.013 15.0 0.2 1.1 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein ALG3 PF05208.8 EPS32535.1 - 7.2e-126 420.3 18.5 8.6e-126 420.0 12.8 1.0 1 0 0 1 1 1 1 ALG3 protein eIF-1a PF01176.14 EPS32536.1 - 5e-13 48.2 0.1 9.3e-13 47.3 0.0 1.5 2 0 0 2 2 2 1 Translation initiation factor 1A / IF-1 DUF3189 PF11385.3 EPS32536.1 - 0.0097 15.4 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3189) MFS_1 PF07690.11 EPS32537.1 - 5.6e-30 104.2 66.8 2.9e-25 88.7 25.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 EPS32538.1 - 1.7e-61 207.6 0.0 2.8e-61 206.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS32538.1 - 9.1e-36 123.2 0.0 1.6e-35 122.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 EPS32538.1 - 3.7e-33 113.0 15.0 5.1e-19 67.7 2.7 2.6 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 EPS32538.1 - 3.5e-20 71.4 30.1 1.9e-11 43.5 6.9 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 EPS32538.1 - 6.3e-15 55.4 2.8 2e-14 53.8 2.0 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EPS32538.1 - 0.015 14.2 0.0 0.025 13.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Peptidase_M6 PF05547.6 EPS32538.1 - 0.4 8.6 0.2 3.6 5.5 0.0 2.0 2 0 0 2 2 2 0 Immune inhibitor A peptidase M6 Uds1 PF15456.1 EPS32538.1 - 2.5 8.0 7.2 0.4 10.6 0.8 2.3 2 0 0 2 2 2 0 Up-regulated During Septation FYVE_2 PF02318.11 EPS32538.1 - 3 7.7 19.5 2 8.3 4.2 2.7 1 1 1 2 2 2 0 FYVE-type zinc finger DUF4309 PF14172.1 EPS32539.1 - 0.12 12.4 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4309) TFCD_C PF12612.3 EPS32540.1 - 4.9e-28 97.8 0.8 2.5e-23 82.5 0.1 3.8 3 0 0 3 3 3 2 Tubulin folding cofactor D C terminal HEAT PF02985.17 EPS32540.1 - 0.00056 19.7 13.8 0.085 12.9 0.0 6.4 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.1 EPS32540.1 - 0.0012 19.0 9.2 1.9 8.8 0.0 5.4 6 0 0 6 6 6 2 HEAT repeats IFRD PF05004.8 EPS32540.1 - 0.0014 17.8 2.1 0.0014 17.8 1.4 2.3 3 0 0 3 3 3 1 Interferon-related developmental regulator (IFRD) Cnd1 PF12717.2 EPS32540.1 - 0.017 15.0 0.2 27 4.5 0.0 4.5 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_N PF03224.9 EPS32540.1 - 0.021 13.9 0.5 66 2.4 0.0 4.3 3 2 1 4 4 4 0 V-ATPase subunit H Vac14_Fab1_bd PF12755.2 EPS32540.1 - 0.089 13.1 0.0 1.2 9.6 0.0 2.9 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EPS32540.1 - 0.32 11.5 0.0 0.32 11.5 0.0 9.0 10 1 1 11 11 11 0 HEAT-like repeat RRM_1 PF00076.17 EPS32541.1 - 7.4e-25 86.3 6.9 6.6e-12 44.8 0.8 2.7 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS32541.1 - 1e-17 63.7 0.1 5.6e-10 38.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS32541.1 - 4.7e-17 61.7 1.5 3.1e-07 30.2 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ATP-synt_D PF01813.12 EPS32542.1 - 4.1e-65 219.0 2.4 5.1e-65 218.7 1.6 1.1 1 0 0 1 1 1 1 ATP synthase subunit D Nup54 PF13874.1 EPS32542.1 - 0.74 9.4 3.5 1.3 8.6 0.2 2.3 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 TPR_14 PF13428.1 EPS32543.1 - 1.7e-14 53.0 3.0 4.6 8.1 0.0 10.6 11 2 2 13 13 12 3 Tetratricopeptide repeat TPR_12 PF13424.1 EPS32543.1 - 1.6e-11 43.9 2.2 0.84 9.6 0.0 7.7 6 1 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 EPS32543.1 - 1.8e-09 37.7 1.2 0.14 12.5 0.0 6.0 5 1 0 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 EPS32543.1 - 3.5e-09 36.1 5.1 0.0017 17.9 0.0 6.8 7 0 0 7 7 7 1 TPR repeat Suf PF05843.9 EPS32543.1 - 2.2e-08 34.1 15.2 0.16 11.6 0.4 5.9 4 1 2 6 6 6 4 Suppressor of forked protein (Suf) TPR_8 PF13181.1 EPS32543.1 - 6.8e-07 28.6 2.2 0.11 12.3 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EPS32543.1 - 4.7e-06 26.4 11.9 0.98 9.2 0.0 6.8 7 0 0 7 7 7 2 Mad3/BUB1 homology region 1 TPR_16 PF13432.1 EPS32543.1 - 1.6e-05 25.4 7.1 0.12 13.1 0.0 5.9 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 EPS32543.1 - 3.7e-05 23.2 13.8 1.9 8.5 0.0 7.9 9 0 0 9 9 7 1 Tetratricopeptide repeat SNAP PF14938.1 EPS32543.1 - 8.5e-05 21.8 4.6 0.035 13.2 0.6 4.7 5 1 0 5 5 5 1 Soluble NSF attachment protein, SNAP TPR_17 PF13431.1 EPS32543.1 - 0.016 15.3 2.2 0.97 9.7 0.0 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat NRDE-2 PF08424.5 EPS32543.1 - 0.021 13.7 10.4 0.32 9.8 0.1 5.1 2 2 3 5 5 5 0 NRDE-2, necessary for RNA interference CKAP2_C PF15297.1 EPS32543.1 - 0.1 11.4 0.4 0.21 10.3 0.3 1.5 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus HAT PF02184.11 EPS32543.1 - 0.13 12.0 7.9 2.3 8.0 0.0 6.4 8 0 0 8 8 6 0 HAT (Half-A-TPR) repeat PPR_2 PF13041.1 EPS32543.1 - 0.15 12.0 0.3 4.1 7.4 0.0 3.3 3 0 0 3 3 3 0 PPR repeat family TPR_6 PF13174.1 EPS32543.1 - 0.29 11.6 13.3 1.1 9.9 0.0 7.0 8 1 0 8 8 8 0 Tetratricopeptide repeat Sec7 PF01369.15 EPS32545.1 - 6.8e-62 208.5 0.1 1.1e-61 207.8 0.1 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EPS32545.1 - 7e-21 74.3 0.0 4.3e-14 52.3 0.0 2.8 2 0 0 2 2 2 2 Guanine nucleotide exchange factor in Golgi transport N-terminal RhoGEF PF00621.15 EPS32546.1 - 1.2e-21 77.4 0.1 1.4e-20 73.9 0.0 2.2 2 0 0 2 2 2 1 RhoGEF domain DUF3507 PF12015.3 EPS32546.1 - 1.5e-09 37.5 0.0 2.6e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) Seryl_tRNA_N PF02403.17 EPS32546.1 - 0.086 12.8 2.8 0.28 11.2 2.0 1.9 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain EMP24_GP25L PF01105.19 EPS32546.1 - 0.19 11.4 1.0 0.85 9.3 0.1 2.3 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD Cep57_CLD_2 PF14197.1 EPS32546.1 - 7.9 6.5 11.0 0.32 10.9 0.3 3.4 3 1 0 3 3 3 0 Centrosome localisation domain of PPC89 ATP_bind_3 PF01171.15 EPS32547.1 - 9.1e-39 132.8 0.0 1.2e-27 96.6 0.0 2.6 2 0 0 2 2 2 2 PP-loop family NAD_synthase PF02540.12 EPS32547.1 - 0.22 10.3 0.0 0.36 9.6 0.0 1.3 1 0 0 1 1 1 0 NAD synthase TPR_11 PF13414.1 EPS32548.1 - 2.9e-13 49.2 5.3 6.8e-07 28.8 0.0 4.2 3 1 1 4 4 4 2 TPR repeat TPR_2 PF07719.12 EPS32548.1 - 1.6e-09 36.9 14.1 0.00048 19.8 0.0 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 EPS32548.1 - 1.8e-08 33.6 0.4 0.015 14.8 0.0 4.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EPS32548.1 - 1.8e-06 27.7 13.2 0.24 11.3 0.8 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 EPS32548.1 - 3.3e-05 23.3 3.2 0.7 9.8 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EPS32548.1 - 0.00032 21.2 21.2 0.24 12.1 2.3 6.6 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 EPS32548.1 - 0.00068 19.9 11.5 0.46 10.8 0.1 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.9 EPS32548.1 - 1.2 9.8 17.0 3.7 8.2 2.4 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EPS32548.1 - 2.1 8.3 8.6 26 4.9 0.3 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 EPS32548.1 - 2.3 9.0 17.0 2.4 9.0 0.5 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3337 PF11816.3 EPS32549.1 - 2.6e-95 319.6 0.0 2.9e-90 303.0 0.5 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.27 EPS32549.1 - 1.5e-25 88.0 14.5 2.4e-07 30.3 0.1 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EPS32549.1 - 0.014 14.2 0.2 2.4 6.8 0.0 2.5 2 1 1 3 3 3 0 Nup133 N terminal like Nup160 PF11715.3 EPS32549.1 - 0.087 10.9 3.1 0.084 10.9 0.2 2.3 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Mito_carr PF00153.22 EPS32550.1 - 1.9e-40 136.4 3.7 2.5e-15 55.9 0.1 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.20 EPS32551.1 - 3.2e-57 193.6 0.0 7.6e-57 192.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS32551.1 - 4.9e-20 71.6 0.0 8e-20 70.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPS32551.1 - 0.0069 16.1 0.4 0.057 13.1 0.1 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Ribosomal_L11_N PF03946.9 EPS32552.1 - 1.3e-26 91.8 0.1 4.2e-26 90.1 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EPS32552.1 - 3.1e-24 84.9 0.1 1.1e-23 83.1 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Svf1 PF08622.5 EPS32553.1 - 6.4e-130 432.8 0.5 7.5e-130 432.6 0.3 1.0 1 0 0 1 1 1 1 Svf1-like CrtC PF07143.6 EPS32553.1 - 0.00057 19.2 0.0 0.001 18.4 0.0 1.5 1 1 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) DHC_N1 PF08385.7 EPS32554.1 - 8.3e-187 622.0 3.3 8.3e-187 622.0 2.3 5.0 7 0 0 7 7 6 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 EPS32554.1 - 2e-128 428.3 5.4 2e-128 428.3 3.8 4.8 6 0 0 6 6 6 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 EPS32554.1 - 4.2e-105 352.3 0.0 4.2e-105 352.3 0.0 2.3 3 0 0 3 3 2 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 EPS32554.1 - 2.8e-78 262.6 0.0 1.5e-77 260.2 0.0 2.2 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 EPS32554.1 - 7.7e-44 149.2 0.2 3.1e-43 147.2 0.1 2.1 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 EPS32554.1 - 2e-41 141.7 0.1 2.8e-40 138.0 0.0 2.6 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.2 EPS32554.1 - 4.3e-41 140.8 8.1 4.3e-41 140.8 5.6 2.0 3 0 0 3 3 3 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 EPS32554.1 - 1.1e-33 115.9 0.8 1.4e-10 41.0 0.0 6.7 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 EPS32554.1 - 1.9e-19 69.7 0.0 1.5e-18 66.8 0.0 2.5 3 0 0 3 3 3 1 P-loop containing dynein motor region D3 AAA PF00004.24 EPS32554.1 - 5.4e-15 55.7 0.0 0.00016 21.9 0.0 5.0 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPS32554.1 - 1.3e-14 54.4 0.0 0.0081 16.2 0.0 5.9 5 0 0 5 5 4 3 AAA domain AAA_17 PF13207.1 EPS32554.1 - 2.3e-09 38.0 0.1 0.037 14.8 0.0 5.6 4 0 0 4 4 4 1 AAA domain AAA_33 PF13671.1 EPS32554.1 - 3.8e-09 36.5 0.1 0.35 10.7 0.0 5.3 4 0 0 4 4 4 3 AAA domain AAA_18 PF13238.1 EPS32554.1 - 4.3e-09 36.7 0.4 0.028 14.7 0.0 5.5 5 0 0 5 5 4 2 AAA domain T2SE PF00437.15 EPS32554.1 - 2.7e-07 29.7 0.0 0.036 12.9 0.0 3.8 4 0 0 4 4 4 2 Type II/IV secretion system protein AAA_16 PF13191.1 EPS32554.1 - 1.5e-06 28.3 10.9 0.12 12.3 0.2 8.2 7 1 1 8 8 7 1 AAA ATPase domain AAA_29 PF13555.1 EPS32554.1 - 8.7e-06 25.1 0.0 2 7.9 0.0 3.6 3 0 0 3 3 3 2 P-loop containing region of AAA domain AAA_19 PF13245.1 EPS32554.1 - 2e-05 24.2 0.2 0.39 10.4 0.0 4.5 4 0 0 4 4 4 1 Part of AAA domain Mg_chelatase PF01078.16 EPS32554.1 - 7.8e-05 21.9 0.8 0.46 9.5 0.0 3.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EPS32554.1 - 0.0011 18.0 5.1 0.6 9.1 0.0 4.5 5 0 0 5 5 4 2 Zeta toxin ABC_tran PF00005.22 EPS32554.1 - 0.0024 18.1 7.4 2.7 8.2 0.0 5.2 5 0 0 5 5 3 2 ABC transporter AAA_25 PF13481.1 EPS32554.1 - 0.01 15.2 0.4 0.62 9.4 0.0 3.5 4 0 0 4 4 4 0 AAA domain RNA_helicase PF00910.17 EPS32554.1 - 0.018 15.2 0.0 39 4.4 0.0 4.4 4 0 0 4 4 4 0 RNA helicase MobB PF03205.9 EPS32554.1 - 0.092 12.4 0.2 13 5.4 0.0 3.3 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Ribonuclease_3 PF00636.21 EPS32555.1 - 2.3e-44 150.4 0.0 2.7e-21 76.1 0.0 3.0 3 0 0 3 3 3 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EPS32555.1 - 3.2e-25 88.5 0.0 1.1e-12 48.0 0.0 3.5 2 2 0 2 2 2 2 Ribonuclease-III-like Dicer_dimer PF03368.9 EPS32555.1 - 2.3e-13 49.7 0.0 7.9e-12 44.8 0.0 2.7 2 0 0 2 2 2 1 Dicer dimerisation domain Helicase_C PF00271.26 EPS32555.1 - 6e-13 48.4 0.1 1.7e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPS32555.1 - 2.4e-11 43.4 0.0 5.4e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EPS32555.1 - 2.2e-10 40.6 0.0 9.2e-10 38.6 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EPS32555.1 - 0.0022 16.8 0.1 0.0043 15.8 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF2075 PF09848.4 EPS32555.1 - 0.022 13.7 0.0 0.04 12.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_26 PF13500.1 EPS32555.1 - 0.082 12.4 0.2 4.5 6.8 0.1 2.4 2 0 0 2 2 2 0 AAA domain TAP42 PF04177.7 EPS32556.1 - 1.4e-106 356.2 7.0 1.6e-106 356.1 4.9 1.0 1 0 0 1 1 1 1 TAP42-like family DUF2600 PF10776.4 EPS32556.1 - 0.0096 14.7 0.7 0.018 13.9 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2600) CEP19 PF14933.1 EPS32556.1 - 0.73 10.1 4.1 1.2 9.4 0.1 2.7 3 1 0 3 3 3 0 CEP19-like protein Cytochrom_B562 PF07361.6 EPS32556.1 - 3.4 8.1 6.3 0.68 10.3 0.1 2.8 3 1 1 4 4 4 0 Cytochrome b562 Porphobil_deam PF01379.15 EPS32557.1 - 4.3e-75 251.3 0.0 5.5e-75 250.9 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EPS32557.1 - 1.2e-16 60.4 0.5 2.4e-16 59.5 0.3 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Lon_C PF05362.8 EPS32558.1 - 3.9e-71 238.5 0.2 1.2e-70 237.0 0.1 1.8 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EPS32558.1 - 9.7e-26 90.7 0.0 2.1e-25 89.6 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EPS32558.1 - 1e-22 80.7 0.0 2.7e-22 79.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EPS32558.1 - 1.1e-07 31.5 0.0 3.2e-07 30.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 EPS32558.1 - 2.1e-07 30.4 0.0 5.5e-07 29.1 0.0 1.8 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.1 EPS32558.1 - 4.6e-06 26.7 4.2 5.2e-06 26.5 0.1 2.9 2 1 0 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 EPS32558.1 - 2.4e-05 24.0 0.1 9.4e-05 22.0 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EPS32558.1 - 3.5e-05 24.6 0.0 0.00014 22.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EPS32558.1 - 7.1e-05 22.4 0.0 0.0002 20.9 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EPS32558.1 - 9.9e-05 21.4 0.1 0.00058 18.9 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EPS32558.1 - 0.00013 20.7 0.1 0.0016 17.2 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus AAA_33 PF13671.1 EPS32558.1 - 0.00031 20.6 0.0 0.001 18.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain Birna_VP4 PF01768.11 EPS32558.1 - 0.00043 19.4 0.0 0.00083 18.4 0.0 1.5 1 0 0 1 1 1 1 Birnavirus VP4 protein AAA_22 PF13401.1 EPS32558.1 - 0.00044 20.4 0.0 0.0026 17.9 0.0 2.3 1 1 1 2 2 1 1 AAA domain Zeta_toxin PF06414.7 EPS32558.1 - 0.001 18.1 0.0 0.0021 17.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin IstB_IS21 PF01695.12 EPS32558.1 - 0.0029 17.0 0.0 0.0078 15.6 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 EPS32558.1 - 0.0053 16.6 0.0 0.015 15.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 EPS32558.1 - 0.0066 16.3 0.0 0.018 14.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EPS32558.1 - 0.025 14.2 0.0 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PhoH PF02562.11 EPS32558.1 - 0.027 13.7 0.0 0.056 12.6 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.17 EPS32558.1 - 0.033 14.3 0.1 0.24 11.6 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_PrkA PF08298.6 EPS32558.1 - 0.04 12.6 0.0 0.35 9.5 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain AAA_18 PF13238.1 EPS32558.1 - 0.042 14.1 0.6 0.1 12.8 0.0 2.0 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.16 EPS32558.1 - 0.043 12.9 0.1 0.1 11.7 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EPS32558.1 - 0.046 13.1 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EPS32558.1 - 0.055 13.0 0.3 0.36 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EPS32558.1 - 0.06 12.9 0.1 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EPS32558.1 - 0.063 13.2 0.0 0.22 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EPS32558.1 - 0.07 12.8 0.0 0.56 9.8 0.0 2.4 1 1 1 2 2 2 0 Archaeal ATPase UPF0079 PF02367.12 EPS32558.1 - 0.077 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 EPS32558.1 - 0.08 12.5 0.1 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EPS32558.1 - 0.091 12.4 0.0 0.35 10.5 0.0 2.0 2 0 0 2 2 1 0 NACHT domain CCDC-167 PF15188.1 EPS32558.1 - 0.12 12.2 3.9 0.27 11.1 0.5 2.7 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 AAA_23 PF13476.1 EPS32558.1 - 0.27 11.5 0.0 0.27 11.5 0.0 2.6 1 1 1 2 2 1 0 AAA domain Ribosomal_L23 PF00276.15 EPS32559.1 - 7.9e-15 54.5 0.0 1.5e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 RIO1 PF01163.17 EPS32560.1 - 7.7e-42 142.7 1.7 2.1e-29 102.2 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.6 EPS32560.1 - 2.9e-32 110.5 0.0 1.3e-31 108.4 0.0 2.0 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.18 EPS32560.1 - 1.7e-07 31.2 0.1 0.00043 20.0 0.0 2.8 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EPS32560.1 - 2.8e-06 26.5 0.1 1.3e-05 24.3 0.0 2.1 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Nop14 PF04147.7 EPS32560.1 - 0.12 10.3 10.4 0.13 10.1 7.2 1.1 1 0 0 1 1 1 0 Nop14-like family Vfa1 PF08432.5 EPS32560.1 - 0.19 11.7 1.7 0.31 11.0 1.2 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 BSP_II PF05432.6 EPS32560.1 - 0.25 10.5 13.4 0.47 9.6 9.3 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CAF1-p150_C2 PF15539.1 EPS32560.1 - 0.33 10.0 2.4 11 5.0 2.3 2.3 2 0 0 2 2 2 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term CobT PF06213.7 EPS32560.1 - 0.37 9.8 14.1 0.63 9.1 9.8 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NOA36 PF06524.7 EPS32560.1 - 0.54 9.4 12.6 0.81 8.8 8.8 1.2 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 EPS32560.1 - 0.91 9.0 12.7 1.7 8.1 8.8 1.4 1 0 0 1 1 1 0 Nucleoplasmin FAM176 PF14851.1 EPS32560.1 - 1.9 8.1 5.8 3.8 7.1 4.1 1.4 1 0 0 1 1 1 0 FAM176 family Sigma70_ner PF04546.8 EPS32560.1 - 7.7 6.0 14.3 2.8 7.5 8.0 1.6 2 0 0 2 2 2 0 Sigma-70, non-essential region Sporozoite_P67 PF05642.6 EPS32560.1 - 7.7 4.2 9.8 12 3.6 6.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Daxx PF03344.10 EPS32560.1 - 8.7 4.6 14.5 12 4.2 10.0 1.1 1 0 0 1 1 1 0 Daxx Family Pox_RNA_Pol_19 PF05320.7 EPS32560.1 - 9.6 5.9 7.9 20 4.9 5.5 1.4 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit PC_rep PF01851.17 EPS32561.1 - 3e-18 64.9 18.1 0.00012 22.0 0.1 8.9 10 0 0 10 10 10 4 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EPS32561.1 - 0.00016 21.8 2.7 1.1 9.6 0.0 4.6 3 2 1 4 4 4 2 HEAT repeats TPR_5 PF12688.2 EPS32561.1 - 0.065 13.2 0.8 5.1 7.1 0.0 3.2 3 1 1 4 4 4 0 Tetratrico peptide repeat DNA_mis_repair PF01119.14 EPS32562.1 - 9.6e-35 118.6 0.2 1.6e-34 117.8 0.1 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EPS32562.1 - 8.4e-15 54.6 0.0 1.8e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EPS32562.1 - 4.8e-10 39.1 0.0 1.2e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DSPc PF00782.15 EPS32563.1 - 1e-30 106.0 0.0 7.7e-22 77.3 0.0 2.4 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EPS32563.1 - 2.1e-06 27.2 0.0 9.1e-05 21.8 0.0 2.3 2 0 0 2 2 2 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 EPS32563.1 - 0.035 13.5 0.0 7.2 6.0 0.0 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 EPS32563.1 - 0.13 12.3 0.0 0.61 10.1 0.0 2.0 2 0 0 2 2 2 0 Inositol hexakisphosphate Protocadherin PF08374.6 EPS32563.1 - 0.48 10.0 1.8 2.7 7.5 0.0 2.1 2 0 0 2 2 2 0 Protocadherin WD40 PF00400.27 EPS32565.1 - 6.4e-06 25.8 1.4 0.0025 17.6 0.0 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat CNH PF00780.17 EPS32565.1 - 0.00021 20.8 0.0 0.033 13.6 0.0 2.4 2 0 0 2 2 2 2 CNH domain Apc4_WD40 PF12894.2 EPS32565.1 - 0.00057 19.3 0.0 0.079 12.4 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.9 EPS32565.1 - 0.002 16.9 0.0 0.015 14.1 0.0 2.1 3 0 0 3 3 3 1 Coatomer WD associated region Hira PF07569.6 EPS32565.1 - 0.036 13.2 0.0 0.13 11.4 0.0 1.8 2 0 0 2 2 2 0 TUP1-like enhancer of split DNA_gyraseA_C PF03989.8 EPS32565.1 - 0.088 12.1 0.1 1.2 8.4 0.0 2.5 2 0 0 2 2 2 0 DNA gyrase C-terminal domain, beta-propeller Fungal_trans PF04082.13 EPS32566.1 - 1.3e-14 53.7 1.0 2.1e-14 53.0 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain EF-hand_6 PF13405.1 EPS32567.1 - 4.7e-08 32.2 0.1 0.0089 15.8 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 EPS32567.1 - 0.00099 19.2 0.9 0.0045 17.1 0.0 2.3 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EPS32567.1 - 0.011 15.0 0.0 0.04 13.2 0.0 1.9 2 0 0 2 2 2 0 EF hand EF-hand_8 PF13833.1 EPS32567.1 - 0.081 12.5 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair TPR_14 PF13428.1 EPS32568.1 - 0.0055 17.2 0.9 7 7.5 0.2 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat SAM_2 PF07647.12 EPS32568.1 - 0.076 12.8 0.0 3.4 7.5 0.0 2.6 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) PPR_3 PF13812.1 EPS32568.1 - 0.11 12.8 1.8 5 7.6 0.0 3.9 3 1 0 3 3 3 0 Pentatricopeptide repeat domain OB_NTP_bind PF07717.11 EPS32569.1 - 4.9e-28 97.2 0.1 1.3e-27 95.9 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EPS32569.1 - 6.4e-24 83.9 0.1 1.7e-23 82.5 0.1 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EPS32569.1 - 2.7e-11 43.1 0.0 9.3e-11 41.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPS32569.1 - 6.8e-08 32.1 0.4 2.3e-07 30.4 0.2 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EPS32569.1 - 4.2e-06 26.9 0.1 2.1e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 EPS32569.1 - 0.00021 20.7 0.1 0.00058 19.3 0.1 1.7 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.9 EPS32569.1 - 0.0015 18.2 0.1 0.0032 17.2 0.1 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain T2SE PF00437.15 EPS32569.1 - 0.0057 15.5 0.0 0.015 14.2 0.0 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein ResIII PF04851.10 EPS32569.1 - 0.016 15.0 0.0 6.5 6.5 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_16 PF13191.1 EPS32569.1 - 0.1 12.5 0.0 0.43 10.5 0.0 2.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 EPS32569.1 - 0.12 12.6 0.0 0.41 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EPS32569.1 - 0.2 11.2 0.0 0.65 9.5 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain PRMT5 PF05185.11 EPS32570.1 - 6.8e-171 569.0 0.0 8.4e-171 568.7 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Glyco_hydro_16 PF00722.16 EPS32571.1 - 1.4e-39 135.2 3.4 1.4e-39 135.2 2.3 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 VPS11_C PF12451.3 EPS32572.1 - 0.12 12.2 3.6 4.1 7.3 0.4 2.8 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal zf-C2H2_4 PF13894.1 EPS32573.1 - 2.2e-06 27.5 12.3 0.0014 18.8 1.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EPS32573.1 - 0.00079 19.6 17.5 0.018 15.3 3.7 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type ZF-HD_dimer PF04770.7 EPS32573.1 - 0.48 10.5 7.5 0.55 10.3 4.2 1.8 1 1 1 2 2 2 0 ZF-HD protein dimerisation region Pkinase PF00069.20 EPS32574.1 - 8.7e-70 234.8 0.0 1.4e-69 234.1 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS32574.1 - 4e-30 104.7 0.0 1.1e-21 77.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EPS32574.1 - 1.5e-06 27.4 0.1 0.12 11.2 0.0 3.1 2 1 1 3 3 3 2 Kinase-like Kdo PF06293.9 EPS32574.1 - 0.028 13.4 0.0 0.046 12.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPS32574.1 - 0.15 11.7 0.0 6.8 6.3 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family DASH_Dad3 PF08656.5 EPS32575.1 - 5.3e-25 86.9 2.2 8.8e-25 86.2 1.5 1.4 1 1 0 1 1 1 1 DASH complex subunit Dad3 TMEM154 PF15102.1 EPS32575.1 - 0.14 11.8 0.7 4.6 6.9 0.0 2.2 2 0 0 2 2 2 0 TMEM154 protein family Ribosomal_S5_C PF03719.10 EPS32576.1 - 3.1e-20 71.2 0.0 6.2e-20 70.2 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 EPS32576.1 - 5.6e-07 29.2 0.4 1.9e-06 27.4 0.0 2.1 1 1 1 2 2 2 1 Ribosomal protein S5, N-terminal domain Tropomodulin PF03250.9 EPS32576.1 - 0.065 12.7 0.5 0.15 11.5 0.4 1.6 1 0 0 1 1 1 0 Tropomodulin tRNA_U5-meth_tr PF05958.6 EPS32577.1 - 6.6e-13 48.0 0.1 8.3e-06 24.7 0.0 2.5 3 0 0 3 3 3 2 tRNA (Uracil-5-)-methyltransferase TRAM PF01938.15 EPS32577.1 - 9e-05 22.1 0.0 0.00024 20.8 0.0 1.7 1 0 0 1 1 1 1 TRAM domain Methyltransf_31 PF13847.1 EPS32577.1 - 0.0002 20.9 0.0 0.00051 19.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.5 EPS32577.1 - 0.046 13.2 0.0 0.09 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase PrmA PF06325.8 EPS32577.1 - 0.1 11.6 0.1 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Actin PF00022.14 EPS32578.1 - 9.3e-90 300.8 0.0 2.1e-89 299.7 0.0 1.5 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EPS32578.1 - 0.047 12.2 0.0 1.4 7.4 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein Asparaginase_2 PF01112.13 EPS32579.1 - 2.2e-39 135.0 0.3 1.6e-19 69.8 0.0 2.2 2 0 0 2 2 2 2 Asparaginase Tfb4 PF03850.9 EPS32580.1 - 8.9e-119 395.8 0.0 1e-118 395.5 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 zf-C2HC5 PF06221.8 EPS32580.1 - 0.083 12.6 3.9 0.17 11.6 2.7 1.5 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type REF PF05755.7 EPS32580.1 - 0.12 12.0 0.1 0.17 11.6 0.1 1.2 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) UNC45-central PF11701.3 EPS32582.1 - 1.2e-40 138.7 3.0 1.8e-38 131.6 0.1 3.6 4 1 0 4 4 4 2 Myosin-binding striated muscle assembly central Arm PF00514.18 EPS32582.1 - 0.0021 17.8 12.8 1.2 9.1 0.1 6.9 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat TPR_11 PF13414.1 EPS32582.1 - 0.067 12.8 0.1 0.19 11.4 0.1 1.8 1 0 0 1 1 1 0 TPR repeat GDPD PF03009.12 EPS32583.1 - 4.3e-73 245.9 0.0 3.8e-72 242.8 0.0 2.4 3 0 0 3 3 3 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 EPS32583.1 - 5.4e-34 116.4 0.1 5.7e-16 58.6 0.1 4.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPS32583.1 - 1.3e-32 111.5 0.9 1.8e-09 37.8 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 EPS32583.1 - 3.1e-29 99.2 2.1 6.6e-05 22.5 0.0 6.8 6 0 0 6 6 6 5 Ankyrin repeat SPX PF03105.14 EPS32583.1 - 2.7e-27 96.2 6.9 3.8e-13 49.8 1.6 3.7 2 1 1 3 3 3 2 SPX domain Ank_5 PF13857.1 EPS32583.1 - 1.1e-24 85.8 0.2 1.8e-08 34.3 0.1 5.9 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPS32583.1 - 1.2e-20 71.5 0.5 0.0024 17.9 0.0 7.6 8 0 0 8 8 8 3 Ankyrin repeat His_Phos_2 PF00328.17 EPS32585.1 - 5.4e-16 58.8 0.0 8.4e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PDGLE PF13190.1 EPS32585.1 - 0.014 15.0 0.1 0.2 11.3 0.0 2.7 3 0 0 3 3 3 0 PDGLE domain CcoS PF03597.10 EPS32585.1 - 0.16 11.4 1.6 0.36 10.3 1.1 1.7 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type TRF PF08558.5 EPS32586.1 - 5.5e-87 291.0 0.9 8.7e-87 290.4 0.6 1.2 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 EPS32586.1 - 1.8e-05 24.7 0.0 3.3e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain TFIID_30kDa PF03540.8 EPS32587.1 - 3.5e-23 81.1 0.1 5.4e-23 80.5 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit DUF1180 PF06679.7 EPS32587.1 - 1.2 9.0 12.1 5.9 6.7 4.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Ribosomal_S19 PF00203.16 EPS32588.1 - 7.8e-21 73.4 0.0 9.3e-21 73.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 Gp_UL130 PF11668.3 EPS32588.1 - 0.069 12.6 0.0 0.081 12.4 0.0 1.1 1 0 0 1 1 1 0 HCMV glycoprotein pUL130 IPK PF03770.11 EPS32589.1 - 3.4e-59 199.7 0.0 5.2e-59 199.2 0.0 1.3 1 0 0 1 1 1 1 Inositol polyphosphate kinase Arb1 PF09692.5 EPS32590.1 - 3.1e-126 421.4 0.0 3.9e-126 421.1 0.0 1.0 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 ADH_zinc_N PF00107.21 EPS32591.1 - 6.4e-30 103.3 0.0 1.1e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPS32591.1 - 2.1e-18 67.4 0.0 3.9e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPS32591.1 - 5.2e-11 42.2 0.0 1.1e-09 38.0 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Sgf11 PF08209.6 EPS32592.1 - 0.19 11.0 4.3 0.18 11.1 0.2 2.8 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) Clp1 PF06807.9 EPS32593.1 - 2.5e-17 63.3 0.0 7.7e-10 38.8 0.0 2.5 2 1 0 2 2 2 2 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EPS32593.1 - 6e-05 22.7 0.0 0.0001 22.0 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 EPS32593.1 - 0.00011 21.8 0.0 0.00032 20.2 0.0 1.7 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 EPS32593.1 - 0.0095 15.9 0.0 0.051 13.5 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 EPS32593.1 - 0.015 15.2 0.0 0.084 12.8 0.0 2.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase SRPRB PF09439.5 EPS32593.1 - 0.13 11.4 0.0 0.28 10.3 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit KilA-N PF04383.8 EPS32594.1 - 0.00012 21.6 0.0 0.04 13.5 0.0 2.7 2 1 1 3 3 3 2 KilA-N domain Rho_GDI PF02115.12 EPS32595.1 - 2.8e-60 203.1 0.2 3.1e-60 203.0 0.1 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Metallophos PF00149.23 EPS32596.1 - 2.9e-42 144.3 1.0 3.8e-42 143.9 0.7 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Adaptin_N PF01602.15 EPS32597.1 - 4.4e-100 335.4 0.0 6e-100 335.0 0.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EPS32597.1 - 3e-10 40.2 0.1 0.00054 20.1 0.0 4.8 4 2 2 6 6 6 3 HEAT repeats HEAT PF02985.17 EPS32597.1 - 1.5e-07 30.9 0.0 0.061 13.4 0.0 5.2 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 EPS32597.1 - 0.005 17.2 2.3 4.7 7.8 0.0 4.9 5 1 0 5 5 5 1 HEAT-like repeat Cohesin_HEAT PF12765.2 EPS32597.1 - 0.083 12.8 1.7 4.7 7.2 0.0 3.6 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion CLASP_N PF12348.3 EPS32597.1 - 0.11 11.8 0.9 5.4 6.3 0.0 3.3 2 1 2 4 4 4 0 CLASP N terminal VHS PF00790.14 EPS32597.1 - 0.11 12.1 0.2 15 5.1 0.0 3.1 3 0 0 3 3 3 0 VHS domain Nop14 PF04147.7 EPS32597.1 - 0.17 9.7 24.2 0.26 9.1 16.7 1.3 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.8 EPS32597.1 - 8.4 6.1 18.3 16 5.2 12.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nuf2 PF03800.9 EPS32599.1 - 4.6e-46 156.4 0.5 1.3e-45 155.0 0.0 2.0 2 0 0 2 2 2 1 Nuf2 family IF-2B PF01008.12 EPS32600.1 - 1.5e-48 165.2 0.0 1.9e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Thioredoxin PF00085.15 EPS32604.1 - 3.1e-32 110.3 0.8 4.2e-32 109.9 0.5 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EPS32604.1 - 3.1e-08 33.8 0.2 5.3e-07 29.8 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 EPS32604.1 - 5.8e-08 32.3 0.1 7.4e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EPS32604.1 - 4.3e-07 29.9 0.1 1.1e-06 28.6 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.1 EPS32604.1 - 8e-05 22.5 0.1 0.00014 21.8 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 EPS32604.1 - 0.00024 20.6 0.7 0.0024 17.4 0.2 2.0 1 1 1 2 2 2 1 Redoxin DUF2847 PF11009.3 EPS32604.1 - 0.0087 15.6 0.0 0.017 14.7 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2847) Thioredoxin_5 PF13743.1 EPS32604.1 - 0.077 12.5 0.1 0.16 11.5 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin Glutaredoxin PF00462.19 EPS32604.1 - 0.1 12.6 0.1 0.18 11.8 0.1 1.5 1 1 0 1 1 1 0 Glutaredoxin Thioredoxin_4 PF13462.1 EPS32604.1 - 0.11 12.4 0.5 2.4 8.1 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin MHYT PF03707.11 EPS32606.1 - 1.3e-10 41.2 14.4 3.5e-06 27.0 0.3 3.9 4 0 0 4 4 4 3 Bacterial signalling protein N terminal repeat UBA PF00627.26 EPS32606.1 - 0.33 10.8 1.5 1.8 8.5 0.0 2.9 4 0 0 4 4 4 0 UBA/TS-N domain DUF775 PF05603.7 EPS32607.1 - 1.6e-61 207.3 0.0 1.8e-61 207.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) NUDIX PF00293.23 EPS32608.1 - 1.3e-09 37.7 0.0 2.1e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Beta-lactamase PF00144.19 EPS32609.1 - 1.2e-45 155.9 0.0 1.9e-45 155.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase RNA_pol_Rpb8 PF03870.10 EPS32610.1 - 1.1e-36 126.0 0.0 1.2e-36 125.9 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 PAXNEB PF05625.6 EPS32611.1 - 2.3e-127 424.8 0.0 2.5e-127 424.6 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein tRNA_int_endo PF01974.12 EPS32613.1 - 3.3e-15 55.6 0.0 7.7e-15 54.4 0.0 1.6 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain MIP-T3 PF10243.4 EPS32613.1 - 0.026 12.9 3.9 0.042 12.3 2.7 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 UPF0086 PF01868.11 EPS32614.1 - 1.3e-32 111.2 0.1 2e-32 110.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function UPF0086 2OG-FeII_Oxy PF03171.15 EPS32615.1 - 6.3e-13 48.8 0.0 1e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EPS32615.1 - 2e-11 44.4 0.0 4e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Cofilin_ADF PF00241.15 EPS32619.1 - 0.00091 19.1 0.0 0.0011 18.8 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein NPIP PF06409.6 EPS32619.1 - 0.13 10.9 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) MoCF_biosynth PF00994.19 EPS32620.1 - 8.3e-36 122.5 0.0 1.3e-35 121.9 0.0 1.2 1 0 0 1 1 1 1 Probable molybdopterin binding domain Ras PF00071.17 EPS32621.1 - 3.4e-58 195.5 0.1 4e-58 195.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPS32621.1 - 3e-18 66.4 0.0 4.1e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPS32621.1 - 9.7e-08 31.4 0.0 1.1e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EPS32621.1 - 1.5e-06 27.8 0.1 7e-06 25.6 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EPS32621.1 - 0.0039 17.1 0.0 0.0046 16.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EPS32621.1 - 0.0064 15.7 0.0 0.011 15.0 0.0 1.4 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF2075 PF09848.4 EPS32621.1 - 0.013 14.5 0.0 1.4 7.7 0.0 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.12 EPS32621.1 - 0.026 13.9 0.7 0.72 9.2 0.1 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF258 PF03193.11 EPS32621.1 - 0.067 12.3 0.1 0.12 11.6 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 adh_short PF00106.20 EPS32623.1 - 1.4e-33 116.2 0.0 1.9e-33 115.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPS32623.1 - 1.5e-15 57.6 0.2 2e-15 57.2 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPS32623.1 - 4.4e-13 49.2 0.0 7.7e-13 48.4 0.0 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EPS32623.1 - 0.0059 16.0 0.3 0.0097 15.3 0.0 1.6 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EPS32623.1 - 0.012 14.5 0.3 0.026 13.4 0.1 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EPS32623.1 - 0.027 14.2 0.2 0.12 12.1 0.1 2.1 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Lin0512_fam PF09585.5 EPS32623.1 - 0.028 13.9 0.2 0.36 10.4 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical protein (Lin0512_fam) NAD_binding_10 PF13460.1 EPS32623.1 - 0.085 12.8 0.8 0.2 11.6 0.2 1.9 2 1 0 2 2 2 0 NADH(P)-binding DUF1776 PF08643.5 EPS32623.1 - 0.11 11.5 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Glyco_hydro_43 PF04616.9 EPS32625.1 - 2.9e-35 121.7 0.1 3.7e-35 121.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 RibD_C PF01872.12 EPS32626.1 - 3.8e-34 118.0 0.0 4.5e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 RibD C-terminal domain Caps_synth PF05704.7 EPS32627.1 - 2.1e-14 53.3 0.0 3.8e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 EPS32627.1 - 0.00036 20.8 0.0 0.00072 19.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif GATA PF00320.22 EPS32628.1 - 6.3e-30 102.2 17.9 7.7e-16 57.1 4.3 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 EPS32628.1 - 2.2e-05 23.6 1.5 0.016 14.5 0.0 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding zf-ribbon_3 PF13248.1 EPS32628.1 - 0.00055 19.0 6.9 0.073 12.3 0.3 2.7 2 1 0 2 2 2 2 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 EPS32628.1 - 0.0038 16.8 4.8 0.19 11.3 0.3 2.5 2 0 0 2 2 2 2 Putative transposase DNA-binding domain Auto_anti-p27 PF06677.7 EPS32628.1 - 0.013 15.2 4.7 0.2 11.4 0.2 2.4 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Zn-ribbon_8 PF09723.5 EPS32628.1 - 0.05 13.5 2.8 1.6 8.7 0.2 2.6 2 0 0 2 2 2 0 Zinc ribbon domain DZR PF12773.2 EPS32628.1 - 0.053 13.3 12.7 1.7 8.4 0.9 3.1 2 2 0 2 2 2 0 Double zinc ribbon eIF-5_eIF-2B PF01873.12 EPS32628.1 - 0.061 12.9 3.5 3 7.5 0.2 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 ArfGap PF01412.13 EPS32628.1 - 0.13 12.0 3.2 0.66 9.7 0.1 2.3 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Ribosomal_S27e PF01667.12 EPS32628.1 - 0.15 11.6 1.3 8.2 6.0 0.1 2.5 2 0 0 2 2 2 0 Ribosomal protein S27 P12 PF12669.2 EPS32628.1 - 0.42 10.8 11.5 0.093 12.9 4.4 2.4 2 0 0 2 2 2 0 Virus attachment protein p12 family HypA PF01155.14 EPS32628.1 - 1.2 8.8 3.2 4.6 6.9 0.1 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family COPI_assoc PF08507.5 EPS32631.1 - 4.8e-45 152.6 4.5 5.3e-45 152.4 3.1 1.0 1 0 0 1 1 1 1 COPI associated protein Tox-WTIP PF15654.1 EPS32631.1 - 0.043 13.4 0.0 0.099 12.2 0.0 1.6 1 0 0 1 1 1 0 Toxin with a conserved tryptophan and TIP tripeptide motif UCR_Fe-S_N PF10399.4 EPS32631.1 - 0.11 11.7 0.0 0.4 9.8 0.0 2.0 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal ExoD PF06055.7 EPS32631.1 - 1.5 7.8 6.6 6.2 5.8 2.5 2.1 2 0 0 2 2 2 0 Exopolysaccharide synthesis, ExoD ALMT PF11744.3 EPS32631.1 - 1.8 7.1 4.3 2.2 6.8 3.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Cg6151-P PF10233.4 EPS32631.1 - 2.1 8.3 8.4 6.1 6.8 5.8 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein CG6151-P SPC12 PF06645.8 EPS32631.1 - 8.2 6.3 7.2 0.71 9.7 1.4 1.9 2 1 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DAO PF01266.19 EPS32633.1 - 5e-25 88.1 0.2 5.9e-25 87.9 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPS32633.1 - 7.7e-05 22.6 0.0 0.0002 21.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EPS32633.1 - 0.004 16.2 0.2 0.013 14.5 0.0 1.9 2 0 0 2 2 2 1 Thi4 family GMC_oxred_N PF00732.14 EPS32633.1 - 0.12 11.4 0.1 0.35 9.9 0.0 1.8 2 0 0 2 2 2 0 GMC oxidoreductase OTU PF02338.14 EPS32634.1 - 6.8e-15 55.7 0.4 1.8e-14 54.3 0.3 1.8 1 1 0 1 1 1 1 OTU-like cysteine protease CUE PF02845.11 EPS32634.1 - 0.0089 15.5 0.0 0.021 14.3 0.0 1.6 1 0 0 1 1 1 1 CUE domain MFS_1 PF07690.11 EPS32635.1 - 4.7e-41 140.6 56.6 1e-29 103.3 24.2 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 EPS32636.1 - 2.2e-09 36.4 6.4 1.7e-08 33.4 4.4 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS32636.1 - 0.0004 20.2 9.3 0.0004 20.2 6.4 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 EPS32638.1 - 6.9e-17 60.6 12.7 0.0037 17.0 0.0 7.7 7 2 0 7 7 7 6 WD domain, G-beta repeat DEAD PF00270.24 EPS32639.1 - 1.9e-41 141.3 0.1 3.1e-41 140.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EPS32639.1 - 2.6e-19 68.5 0.0 5e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EPS32639.1 - 7.1e-19 67.4 0.0 1.9e-18 66.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPS32639.1 - 0.00091 19.0 1.0 0.0026 17.5 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit BSP_II PF05432.6 EPS32639.1 - 1.5 7.9 10.7 0.25 10.5 4.1 2.0 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) FAM176 PF14851.1 EPS32639.1 - 8.8 5.9 7.2 0.59 9.7 0.6 2.3 3 0 0 3 3 3 0 FAM176 family Pantoate_ligase PF02569.10 EPS32640.1 - 1.3e-82 276.6 0.0 2.3e-82 275.9 0.0 1.4 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase Acyltransferase PF01553.16 EPS32641.1 - 1e-16 60.6 0.0 2.2e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase GDA1_CD39 PF01150.12 EPS32642.1 - 2.1e-104 349.4 0.0 2.8e-104 349.0 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family LRR_9 PF14580.1 EPS32643.1 - 1.3e-50 171.4 1.1 1.3e-50 171.3 0.1 1.5 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.2 EPS32643.1 - 3.1e-08 33.0 15.7 0.00012 21.5 2.4 4.1 2 2 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPS32643.1 - 6.1e-08 32.2 14.0 5.7e-05 22.7 3.7 3.2 2 2 1 3 3 3 2 Leucine rich repeat HTH_38 PF13936.1 EPS32643.1 - 0.00073 19.0 0.6 0.0014 18.1 0.4 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain LRR_7 PF13504.1 EPS32643.1 - 0.062 13.5 7.5 10 6.8 0.3 4.7 5 0 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 EPS32643.1 - 0.068 13.2 2.4 26 5.3 0.1 4.3 4 0 0 4 4 4 0 Leucine Rich repeat EIAV_Rev PF11129.3 EPS32643.1 - 0.12 12.3 0.1 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Rev protein of equine infectious anaemia virus DUF4349 PF14257.1 EPS32643.1 - 0.27 10.4 1.9 0.4 9.8 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) LRR_1 PF00560.28 EPS32643.1 - 1.3 9.3 15.0 11 6.5 0.2 5.1 5 1 0 5 5 5 0 Leucine Rich Repeat FAD_binding_4 PF01565.18 EPS32646.1 - 1.2e-18 66.9 0.5 2.2e-18 66.0 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EPS32646.1 - 0.0019 18.0 0.0 0.0065 16.3 0.0 1.9 1 0 0 1 1 1 1 Berberine and berberine like ADH_zinc_N PF00107.21 EPS32647.1 - 4.4e-22 78.0 0.0 8.6e-22 77.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPS32647.1 - 1.1e-15 58.5 0.0 2.5e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPS32647.1 - 3e-09 36.5 0.1 1.8e-08 34.1 0.1 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Amidohydro_1 PF01979.15 EPS32649.1 - 9.2e-35 120.8 0.1 1.2e-34 120.5 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EPS32649.1 - 2.2e-18 67.2 1.5 5.7e-17 62.6 1.0 2.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EPS32649.1 - 3.4e-12 46.0 0.0 9.6e-12 44.5 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EPS32649.1 - 8e-08 31.8 1.5 3.6e-06 26.4 0.0 2.3 1 1 0 2 2 2 2 Amidohydrolase family DHO_dh PF01180.16 EPS32649.1 - 0.1 11.5 0.1 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase MFS_1 PF07690.11 EPS32650.1 - 4e-41 140.8 53.7 1.3e-40 139.2 36.0 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily FTR1 PF03239.9 EPS32651.1 - 4e-88 295.2 6.9 5.1e-88 294.9 4.8 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF4229 PF14012.1 EPS32651.1 - 0.24 11.3 0.1 0.24 11.3 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4229) DUF2232 PF09991.4 EPS32651.1 - 1.7 7.5 9.3 0.17 10.8 1.9 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) Yip1 PF04893.12 EPS32651.1 - 9.6 5.6 24.5 32 3.9 12.5 2.6 1 1 1 2 2 2 0 Yip1 domain Cu-oxidase_2 PF07731.9 EPS32652.1 - 7.8e-44 148.5 12.0 2.5e-40 137.2 0.5 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EPS32652.1 - 3.1e-40 136.5 4.4 9.8e-38 128.5 2.3 2.8 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 EPS32652.1 - 5.1e-36 123.9 6.0 3.4e-33 114.7 0.4 3.2 3 0 0 3 3 3 2 Multicopper oxidase COX2 PF00116.15 EPS32652.1 - 0.023 14.5 0.4 0.21 11.4 0.1 2.8 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, periplasmic domain Dickkopf_N PF04706.7 EPS32653.1 - 0.13 12.3 3.7 0.21 11.7 2.6 1.2 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region DUF221 PF02714.10 EPS32657.1 - 8.6e-112 373.1 15.9 8.6e-112 373.1 11.0 2.9 3 0 0 3 3 3 2 Domain of unknown function DUF221 RSN1_TM PF13967.1 EPS32657.1 - 3.5e-40 137.1 5.0 3.5e-40 137.1 3.5 2.3 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EPS32657.1 - 9.4e-33 111.9 0.3 2.1e-32 110.8 0.2 1.6 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 EPS32657.1 - 1.2e-20 73.7 0.6 2.6e-20 72.6 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) ODV-E18 PF10717.4 EPS32657.1 - 2 7.9 13.4 0.58 9.6 1.9 3.2 3 0 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 TPR_12 PF13424.1 EPS32658.1 - 0.04 13.8 0.2 0.15 12.0 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Trans_reg_C PF00486.23 EPS32658.1 - 0.071 13.0 0.1 1 9.3 0.0 2.7 3 0 0 3 3 3 0 Transcriptional regulatory protein, C terminal MCM PF00493.18 EPS32659.1 - 9e-132 438.8 0.1 1.3e-131 438.3 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EPS32659.1 - 5.1e-19 68.9 0.1 3.2e-18 66.3 0.0 2.4 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EPS32659.1 - 8.1e-05 21.8 0.0 0.00096 18.3 0.0 2.3 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EPS32659.1 - 0.0043 16.5 0.0 0.0093 15.4 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 EPS32659.1 - 0.0065 16.0 0.0 0.018 14.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EPS32659.1 - 0.0067 16.1 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Vma12 PF11712.3 EPS32661.1 - 0.15 11.7 0.2 0.22 11.2 0.2 1.3 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Transformer PF06495.6 EPS32662.1 - 0.58 10.0 6.5 0.7 9.7 4.5 1.1 1 0 0 1 1 1 0 Fruit fly transformer protein Fungal_trans_2 PF11951.3 EPS32664.1 - 6.1e-26 90.9 0.1 7.7e-25 87.2 0.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS32664.1 - 0.00088 19.1 11.8 0.0014 18.4 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4281 PF14108.1 EPS32664.1 - 0.11 12.5 2.8 0.25 11.4 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4281) DUF3445 PF11927.3 EPS32665.1 - 1.1e-81 273.9 0.0 1.4e-81 273.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Peptidase_C97 PF05903.9 EPS32666.1 - 6.5e-42 142.8 0.0 1.1e-41 142.1 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.6 EPS32666.1 - 3.5e-41 140.7 0.1 4.5e-41 140.4 0.1 1.2 1 0 0 1 1 1 1 PUL domain Thioredoxin PF00085.15 EPS32666.1 - 1e-15 57.2 0.0 2e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EPS32666.1 - 0.0024 18.0 0.1 0.011 15.8 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 EPS32666.1 - 0.0034 17.1 0.0 0.0082 15.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin domain DUF2847 PF11009.3 EPS32666.1 - 0.064 12.8 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2847) RRM_1 PF00076.17 EPS32668.1 - 8.4e-15 54.1 0.0 1.3e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS32668.1 - 4.6e-12 45.7 0.0 7.1e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EPS32668.1 - 3.3e-05 24.2 0.4 3.3e-05 24.2 0.2 2.6 2 1 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 EPS32668.1 - 0.0024 17.6 0.0 0.0038 17.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HSP33 PF01430.14 EPS32668.1 - 0.14 11.2 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Hsp33 protein FXR1P_C PF12235.3 EPS32668.1 - 1.2 9.2 6.8 5.7 7.0 0.3 2.3 2 0 0 2 2 2 0 Fragile X-related 1 protein C terminal Snf7 PF03357.16 EPS32669.1 - 3.4e-19 68.8 11.0 3.4e-19 68.8 7.6 1.9 2 0 0 2 2 2 1 Snf7 Tcell_CD4_Cterm PF12104.3 EPS32669.1 - 0.017 14.7 0.4 0.017 14.7 0.3 2.1 2 0 0 2 2 2 0 T cell CD4 receptor C terminal region MerR-DNA-bind PF09278.6 EPS32669.1 - 0.039 14.3 10.9 2.7 8.4 0.4 3.8 3 1 0 3 3 3 0 MerR, DNA binding NAGLU_C PF12972.2 EPS32669.1 - 0.079 12.3 0.7 0.11 11.8 0.5 1.2 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain PhoU PF01895.14 EPS32669.1 - 0.11 12.9 3.5 0.49 10.8 0.1 2.5 2 1 1 3 3 3 0 PhoU domain DUF4473 PF14747.1 EPS32669.1 - 0.23 11.6 1.9 9.4 6.5 0.0 3.2 4 0 0 4 4 3 0 Domain of unknown function (DUF4473) BMFP PF04380.8 EPS32669.1 - 0.95 9.6 11.6 0.24 11.5 0.6 4.3 3 1 2 5 5 5 0 Membrane fusogenic activity AAA_13 PF13166.1 EPS32669.1 - 1.4 7.2 8.8 2.3 6.5 6.1 1.4 1 1 0 1 1 1 0 AAA domain Spectrin PF00435.16 EPS32669.1 - 2.9 8.2 10.8 0.44 10.8 0.9 3.2 2 2 0 2 2 2 0 Spectrin repeat Cytochrom_B562 PF07361.6 EPS32669.1 - 3.3 8.1 7.6 2.9 8.3 0.4 3.3 1 1 1 2 2 2 0 Cytochrome b562 DASH_Duo1 PF08651.5 EPS32669.1 - 6.3 6.4 6.8 2 8.0 0.3 3.0 3 1 1 4 4 4 0 DASH complex subunit Duo1 Atg14 PF10186.4 EPS32669.1 - 7.3 5.4 16.0 0.75 8.6 7.7 1.7 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 TPR_MLP1_2 PF07926.7 EPS32669.1 - 8.3 6.1 13.4 63 3.3 9.2 2.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein CS PF04969.11 EPS32670.1 - 2.7e-10 40.6 0.0 4.5e-10 39.9 0.0 1.4 1 1 0 1 1 1 1 CS domain zf-CCCH PF00642.19 EPS32671.1 - 0.00014 21.3 2.2 0.00014 21.3 1.5 2.5 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DAO PF01266.19 EPS32672.1 - 3.2e-20 72.3 0.0 4.2e-20 71.9 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EPS32672.1 - 0.029 14.7 0.1 0.068 13.5 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EPS32672.1 - 0.094 11.5 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.1 EPS32672.1 - 0.1 12.6 0.2 0.37 10.8 0.1 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF3822 PF12864.2 EPS32674.1 - 0.57 9.3 0.0 0.93 8.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3822) TP6A_N PF04406.9 EPS32675.1 - 0.15 11.7 0.4 0.42 10.2 0.3 1.8 1 0 0 1 1 1 0 Type IIB DNA topoisomerase adh_short PF00106.20 EPS32676.1 - 1.4e-19 70.6 0.0 1.8e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPS32676.1 - 8.3e-10 38.8 0.0 1e-09 38.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPS32676.1 - 1.5e-08 34.4 0.0 2.3e-08 33.9 0.0 1.3 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.5 EPS32676.1 - 0.0015 17.7 0.0 0.0018 17.4 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DUF460 PF04312.8 EPS32676.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF460) Peripla_BP_5 PF13433.1 EPS32676.1 - 0.13 11.0 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Periplasmic binding protein domain zf-HIT PF04438.11 EPS32677.1 - 2.4e-10 39.8 10.4 4.2e-10 39.0 7.2 1.4 1 0 0 1 1 1 1 HIT zinc finger Reo_sigmaC PF04582.7 EPS32678.1 - 3.8e-06 26.3 15.9 0.00026 20.2 3.1 1.7 1 1 1 2 2 2 2 Reovirus sigma C capsid protein AAA_13 PF13166.1 EPS32678.1 - 0.0025 16.3 0.2 0.0053 15.2 0.1 1.4 1 1 0 1 1 1 1 AAA domain Spc7 PF08317.6 EPS32678.1 - 0.0031 16.2 1.7 0.0055 15.4 1.2 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Cast PF10174.4 EPS32678.1 - 0.0043 15.1 5.5 0.0059 14.7 3.8 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone DUF1640 PF07798.6 EPS32678.1 - 0.031 14.3 4.2 0.22 11.5 0.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) WEMBL PF05701.6 EPS32678.1 - 0.061 11.7 0.8 0.083 11.3 0.6 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Baculo_PEP_C PF04513.7 EPS32678.1 - 0.1 12.4 8.9 0.24 11.1 3.4 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG6 PF04111.7 EPS32678.1 - 0.11 11.4 1.7 0.17 10.9 1.2 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 LPP PF04728.8 EPS32678.1 - 0.12 12.2 6.4 6.3 6.6 0.1 3.9 4 0 0 4 4 4 0 Lipoprotein leucine-zipper Macoilin PF09726.4 EPS32678.1 - 0.17 10.1 4.3 0.37 9.0 3.0 1.6 1 0 0 1 1 1 0 Transmembrane protein DUF1664 PF07889.7 EPS32678.1 - 0.22 11.3 7.8 3.7 7.3 0.5 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.4 EPS32678.1 - 0.27 11.0 5.1 0.72 9.6 1.1 2.9 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF972 PF06156.8 EPS32678.1 - 0.48 10.7 1.9 5.3 7.4 0.2 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Atg14 PF10186.4 EPS32678.1 - 0.65 8.8 9.4 25 3.6 6.5 2.3 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 EPS32678.1 - 1.8 8.0 6.1 1 8.8 1.4 2.1 1 1 1 2 2 2 0 IncA protein Filament PF00038.16 EPS32678.1 - 3 7.2 8.0 2.1 7.7 1.4 2.1 1 1 1 2 2 2 0 Intermediate filament protein Syntaxin PF00804.20 EPS32678.1 - 4.4 7.5 7.7 14 5.8 4.0 2.6 1 1 1 2 2 2 0 Syntaxin ATG16 PF08614.6 EPS32678.1 - 6.5 6.5 10.7 6.7 6.4 5.1 2.6 2 1 0 2 2 1 0 Autophagy protein 16 (ATG16) WASH-7_C PF14746.1 EPS32679.1 - 0.077 12.5 1.7 0.15 11.6 1.2 1.4 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal Peptidase_C48 PF02902.14 EPS32680.1 - 3.7e-26 92.0 0.0 5.4e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain HTH_16 PF12645.2 EPS32681.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Glyco_hydro_18 PF00704.23 EPS32682.1 - 5.6e-69 233.1 0.2 1.3e-68 231.9 0.1 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EPS32682.1 - 5.2e-11 42.3 51.6 1.1e-08 34.8 4.2 6.9 9 1 1 10 10 10 3 Chitin recognition protein Pectate_lyase_3 PF12708.2 EPS32683.1 - 2.6e-68 230.5 8.9 1.1e-49 169.5 2.3 2.5 2 0 0 2 2 2 2 Pectate lyase superfamily protein LysM PF01476.15 EPS32683.1 - 6.1e-06 26.0 0.1 0.0075 16.1 0.0 3.2 3 0 0 3 3 3 2 LysM domain End_N_terminal PF12218.3 EPS32683.1 - 3.3e-05 23.2 0.1 0.15 11.5 0.0 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase PAP2 PF01569.16 EPS32686.1 - 9.2e-18 64.1 1.8 9.2e-18 64.1 1.3 1.8 1 1 0 1 1 1 1 PAP2 superfamily Ras PF00071.17 EPS32688.1 - 9.5e-49 164.8 0.0 1.1e-48 164.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPS32688.1 - 1.7e-12 47.8 0.0 2.4e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPS32688.1 - 1.7e-05 24.1 0.0 5.4e-05 22.5 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EPS32688.1 - 0.016 14.4 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EPS32688.1 - 0.03 13.4 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DASH_Dad1 PF08649.5 EPS32689.1 - 1.8e-22 78.7 2.8 2.2e-22 78.4 1.9 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 AbiH PF14253.1 EPS32689.1 - 0.12 11.9 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH DUF1645 PF07816.6 EPS32690.1 - 0.98 9.8 6.2 5.1 7.5 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1645) LSM PF01423.17 EPS32692.1 - 2.9e-19 68.3 0.0 3.4e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF866 PF05907.8 EPS32693.1 - 2.1e-50 170.3 0.2 2.3e-50 170.2 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) zf-PHD-like PF15446.1 EPS32693.1 - 0.0017 17.6 0.1 0.0022 17.3 0.0 1.1 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain FAD_binding_3 PF01494.14 EPS32694.1 - 1.1e-72 245.0 0.0 1.4e-72 244.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EPS32694.1 - 1.5e-39 135.3 0.1 2.5e-39 134.5 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.19 EPS32694.1 - 0.0035 16.2 0.0 0.016 14.0 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EPS32694.1 - 0.0045 17.3 0.0 0.026 14.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EPS32694.1 - 0.014 14.2 0.1 0.061 12.2 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_8 PF13450.1 EPS32694.1 - 0.04 13.9 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EPS32694.1 - 0.051 13.4 0.0 0.27 11.1 0.0 2.2 3 1 1 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPS32694.1 - 0.082 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.11 EPS32694.1 - 0.11 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA V-ATPase_H_C PF11698.3 EPS32695.1 - 0.11 12.4 0.1 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 V-ATPase subunit H DDHD PF02862.12 EPS32698.1 - 1e-44 153.0 0.2 2.1e-26 93.1 0.0 3.1 2 1 1 3 3 3 2 DDHD domain Abhydrolase_6 PF12697.2 EPS32698.1 - 0.0049 16.7 0.0 0.014 15.3 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPS32698.1 - 0.047 13.4 0.0 0.098 12.4 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family CBM-like PF14683.1 EPS32699.1 - 3.5e-35 121.1 0.1 1.1e-34 119.4 0.0 1.9 3 0 0 3 3 3 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 EPS32699.1 - 5.6e-23 80.8 1.8 8.5e-23 80.2 0.0 2.2 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 EPS32699.1 - 7.6e-07 29.0 0.1 2.4e-06 27.4 0.1 1.9 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain MoCF_biosynth PF00994.19 EPS32701.1 - 6.5e-49 165.0 0.0 8.8e-26 90.0 0.0 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 EPS32701.1 - 9.8e-35 119.3 0.8 2.7e-34 117.8 0.8 1.6 2 0 0 2 2 2 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 EPS32701.1 - 4.1e-15 55.4 0.1 1.1e-14 54.1 0.1 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) SelP_N PF04592.9 EPS32701.1 - 3.1 7.1 13.7 5 6.4 9.5 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region ATP-synt_C PF00137.16 EPS32702.1 - 8.5e-25 86.4 28.9 9.4e-16 57.4 5.9 2.4 3 0 0 3 3 3 2 ATP synthase subunit C Oxidored_q2 PF00420.19 EPS32702.1 - 3.7 7.2 7.2 1.1 8.9 1.2 2.7 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF4040 PF13244.1 EPS32702.1 - 4.5 7.3 6.9 15 5.6 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4040) Cation_ATPase_C PF00689.16 EPS32702.1 - 4.7 6.7 6.9 4.9 6.6 0.1 2.5 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus Ras PF00071.17 EPS32703.1 - 2.4e-59 199.3 0.2 3.1e-59 198.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPS32703.1 - 7.8e-21 74.7 0.0 1.2e-20 74.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPS32703.1 - 1.3e-17 63.5 0.1 1.6e-17 63.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EPS32703.1 - 2.3e-07 30.4 0.0 1.1e-06 28.2 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EPS32703.1 - 4e-06 26.1 0.1 4.9e-06 25.8 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EPS32703.1 - 4.8e-06 25.9 0.0 7.1e-06 25.3 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EPS32703.1 - 1.1e-05 25.4 0.0 1.6e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EPS32703.1 - 0.023 14.5 0.1 2.9 7.6 0.0 2.6 2 1 0 2 2 2 0 Dynamin family AAA_14 PF13173.1 EPS32703.1 - 0.054 13.4 0.2 0.098 12.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EPS32703.1 - 0.06 12.5 0.1 0.87 8.7 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EPS32703.1 - 0.12 12.5 0.0 1.1 9.4 0.0 2.4 1 1 0 1 1 1 0 AAA domain MFS_1 PF07690.11 EPS32704.1 - 5.7e-42 143.6 41.1 5.7e-42 143.6 28.5 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS32704.1 - 6.8e-12 44.7 11.1 6.8e-12 44.7 7.7 2.3 1 1 1 2 2 2 1 Sugar (and other) transporter Kei1 PF08552.6 EPS32705.1 - 5.3e-61 205.5 2.1 6.4e-61 205.3 1.5 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 NIR_SIR PF01077.17 EPS32707.1 - 6.7e-50 168.5 0.0 1.7e-42 144.4 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 EPS32707.1 - 5.8e-28 96.3 0.0 4.4e-13 48.6 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 EPS32707.1 - 5.3e-25 88.0 0.0 1.1e-24 87.0 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 EPS32707.1 - 3.2e-06 26.8 0.5 1.1e-05 25.0 0.1 2.0 2 0 0 2 2 2 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg RNA_pol PF00940.14 EPS32708.1 - 2e-171 569.9 0.0 2.7e-171 569.5 0.0 1.2 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 EPS32708.1 - 5.3e-71 239.4 0.2 7.9e-71 238.9 0.2 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Sin_N PF04801.8 EPS32709.1 - 2.2e-25 89.4 0.7 9.9e-25 87.2 0.5 1.8 1 1 0 1 1 1 1 Sin-like protein conserved region adh_short_C2 PF13561.1 EPS32710.1 - 8.3e-23 81.3 0.0 1.1e-22 81.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EPS32710.1 - 1.6e-19 70.4 0.3 1.6e-19 70.4 0.2 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EPS32710.1 - 2.6e-08 33.7 0.2 6.2e-08 32.5 0.2 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EPS32710.1 - 0.0048 16.3 0.0 0.0077 15.6 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EPS32710.1 - 0.02 13.8 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EPS32710.1 - 0.025 13.3 0.2 0.031 12.9 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family UPRTase PF14681.1 EPS32710.1 - 0.085 12.0 0.0 0.23 10.6 0.0 1.7 1 1 1 2 2 2 0 Uracil phosphoribosyltransferase adh_short_C2 PF13561.1 EPS32711.1 - 7.8e-29 101.1 1.3 9.1e-29 100.9 0.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EPS32711.1 - 2.7e-28 98.9 2.4 3.4e-28 98.6 1.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPS32711.1 - 1.1e-15 57.7 1.8 1.5e-15 57.3 1.2 1.1 1 0 0 1 1 1 1 KR domain NAD_Gly3P_dh_N PF01210.18 EPS32711.1 - 0.0025 17.5 0.6 0.0042 16.8 0.4 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AdoHcyase_NAD PF00670.16 EPS32711.1 - 0.013 15.3 1.8 0.022 14.5 1.2 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Epimerase PF01370.16 EPS32711.1 - 0.023 14.1 1.2 0.035 13.5 0.9 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EPS32711.1 - 0.035 13.7 1.5 0.061 12.9 1.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 EPS32711.1 - 0.043 13.6 0.1 0.1 12.3 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Methyltransf_31 PF13847.1 EPS32711.1 - 0.051 13.1 0.1 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Beta-lactamase PF00144.19 EPS32712.1 - 4.9e-46 157.2 0.0 7.9e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase DAP_C PF07932.7 EPS32712.1 - 4.6e-38 129.2 0.2 1e-37 128.1 0.1 1.6 1 0 0 1 1 1 1 D-aminopeptidase, domain C DAP_B PF07930.7 EPS32712.1 - 0.00015 21.4 0.1 0.00065 19.3 0.0 2.0 2 0 0 2 2 2 1 D-aminopeptidase, domain B Fungal_trans PF04082.13 EPS32714.1 - 2.2e-36 125.0 0.0 4.4e-36 124.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS32714.1 - 2.8e-09 36.7 9.1 4.7e-09 36.0 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FimP PF09766.4 EPS32714.1 - 0.17 10.9 13.9 0.28 10.2 9.6 1.2 1 0 0 1 1 1 0 Fms-interacting protein Suf PF05843.9 EPS32714.1 - 0.45 10.2 12.4 0.8 9.3 8.6 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Hid1 PF12722.2 EPS32714.1 - 7.2 4.1 8.3 9.7 3.7 5.7 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Radical_SAM PF04055.16 EPS32715.1 - 1.9e-09 37.9 0.0 2.9e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EPS32715.1 - 9e-06 25.8 0.0 1.8e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EPS32715.1 - 0.00045 20.2 0.1 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain DUF92 PF01940.11 EPS32716.1 - 2.2e-58 197.1 9.9 2.8e-58 196.7 6.9 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF92 CsoS2_M PF12288.3 EPS32716.1 - 0.0045 16.2 0.1 0.0069 15.6 0.1 1.3 1 0 0 1 1 1 1 Carboxysome shell peptide mid-region PHO4 PF01384.15 EPS32719.1 - 9.4e-101 336.7 19.5 1.1e-100 336.4 13.5 1.0 1 0 0 1 1 1 1 Phosphate transporter family PgpA PF04608.8 EPS32719.1 - 0.093 12.5 5.1 0.2 11.4 1.3 2.7 2 0 0 2 2 2 0 Phosphatidylglycerophosphatase A SLAC1 PF03595.12 EPS32720.1 - 1.8e-62 210.9 42.6 2.1e-62 210.7 29.5 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel TPR_2 PF07719.12 EPS32722.1 - 0.007 16.1 1.2 2.8 8.0 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EPS32722.1 - 0.036 13.7 1.8 1.3 8.7 0.0 2.8 3 0 0 3 3 3 0 TPR repeat TPR_21 PF09976.4 EPS32722.1 - 0.069 13.0 0.1 0.069 13.0 0.1 1.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.9 EPS32722.1 - 1.8 9.2 4.5 3.4 8.3 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Methyltransf_33 PF10017.4 EPS32723.1 - 2.2e-31 108.3 0.1 4.9e-31 107.2 0.0 1.6 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 EPS32723.1 - 7.3e-23 81.2 2.8 2e-21 76.5 1.9 2.2 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 EPS32723.1 - 1.7e-09 38.0 0.5 5.2e-09 36.5 0.1 2.0 2 0 0 2 2 2 1 DinB superfamily Methyltransf_25 PF13649.1 EPS32723.1 - 0.042 14.2 0.0 0.092 13.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF222 PF02720.12 EPS32723.1 - 0.045 12.8 0.0 0.077 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF222) TFIIA_gamma_C PF02751.9 EPS32726.1 - 3.4e-27 93.9 2.3 4.9e-27 93.4 1.6 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 EPS32726.1 - 6.6e-26 89.6 0.2 9.3e-26 89.1 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain Hexokinase_2 PF03727.11 EPS32728.1 - 1.8e-28 99.3 0.0 1.6e-22 79.8 0.0 2.2 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 EPS32728.1 - 3.7e-28 98.2 0.0 3.2e-26 91.9 0.0 2.9 1 1 0 1 1 1 1 Hexokinase GILT PF03227.11 EPS32729.1 - 4.4e-09 36.1 0.1 1.3e-08 34.6 0.0 1.7 2 0 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) WH1 PF00568.18 EPS32730.1 - 0.11 12.2 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 WH1 domain MFS_1 PF07690.11 EPS32731.1 - 1.1e-31 109.8 28.4 1.1e-31 109.8 19.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EPS32731.1 - 0.0027 17.4 6.2 0.75 9.6 1.4 2.9 2 0 0 2 2 2 2 MFS_1 like family adh_short PF00106.20 EPS32732.1 - 4.9e-27 94.8 1.4 6.5e-27 94.4 1.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPS32732.1 - 5.1e-26 91.9 0.1 6.5e-26 91.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPS32732.1 - 1.5e-13 50.8 0.7 2.7e-13 49.9 0.5 1.4 1 0 0 1 1 1 1 KR domain Pyr_redox PF00070.22 EPS32732.1 - 0.053 13.9 0.0 0.1 13.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_2 PF03446.10 EPS32732.1 - 0.073 12.9 0.1 0.65 9.8 0.0 2.2 1 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Spc97_Spc98 PF04130.8 EPS32733.1 - 3.3e-78 263.3 0.0 5.3e-78 262.6 0.0 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family ThiF PF00899.16 EPS32734.1 - 1.3e-51 174.0 0.0 1.4e-30 105.8 0.0 2.5 2 0 0 2 2 2 2 ThiF family UBACT PF02134.16 EPS32734.1 - 3.4e-39 132.2 1.2 4.1e-25 87.1 0.1 2.7 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_C PF09358.5 EPS32734.1 - 3.5e-37 127.3 0.0 9.6e-37 125.9 0.0 1.7 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBA_e1_thiolCys PF10585.4 EPS32734.1 - 1.5e-24 85.0 2.1 1.6e-21 75.3 0.4 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site GST_N_2 PF13409.1 EPS32736.1 - 1.8e-22 79.0 0.1 5.5e-22 77.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EPS32736.1 - 1.1e-16 60.5 0.0 2.4e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EPS32736.1 - 8.2e-06 25.7 0.0 1.8e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EPS32736.1 - 4.7e-05 23.7 0.0 0.00012 22.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EPS32736.1 - 4.8e-05 23.4 0.1 0.0035 17.5 0.0 2.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Mito_carr PF00153.22 EPS32737.1 - 2.1e-67 222.9 5.6 8.3e-24 83.1 0.1 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 EPS32737.1 - 2.1e-23 82.2 3.5 9.6e-12 44.8 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EPS32737.1 - 3.5e-21 72.8 5.5 3.1e-06 26.0 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EPS32737.1 - 1.6e-15 55.4 5.1 0.00011 21.8 0.0 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 EPS32737.1 - 1.9e-15 55.4 7.7 0.00011 21.3 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 EPS32737.1 - 1.1e-12 47.3 4.0 6.1e-07 28.9 0.1 3.6 2 2 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EPS32737.1 - 7.8e-10 38.7 0.1 0.00081 19.3 0.0 2.4 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EPS32737.1 - 0.038 13.7 2.4 3.5 7.4 0.2 2.8 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.1 EPS32737.1 - 0.071 12.7 0.5 11 5.7 0.0 3.3 3 0 0 3 3 3 0 EF hand Cyclin_N PF00134.18 EPS32738.1 - 3.5e-11 42.7 0.1 1.1e-10 41.1 0.0 1.9 3 0 0 3 3 3 1 Cyclin, N-terminal domain DUF4452 PF14618.1 EPS32739.1 - 1.8e-71 239.2 11.3 2.1e-71 239.0 7.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) Uds1 PF15456.1 EPS32740.1 - 0.69 9.9 6.8 1 9.3 4.7 1.5 1 1 0 1 1 1 0 Up-regulated During Septation SNARE PF05739.14 EPS32741.1 - 1.8e-13 49.9 0.9 5.4e-13 48.4 0.6 1.9 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.4 EPS32741.1 - 0.079 12.3 0.0 0.19 11.1 0.0 1.4 1 1 0 1 1 1 0 Membrane fusion protein Use1 DUF2968 PF11180.3 EPS32741.1 - 0.16 11.3 3.5 0.43 9.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) WXG100 PF06013.7 EPS32741.1 - 0.17 11.9 1.7 0.89 9.5 0.2 2.7 3 0 0 3 3 3 0 Proteins of 100 residues with WXG HrpB7 PF09486.5 EPS32741.1 - 0.32 10.9 5.1 0.42 10.5 0.1 2.4 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) zf-TRAF PF02176.13 EPS32742.1 - 7e-15 55.1 31.6 1.7e-09 37.9 1.9 4.4 2 1 3 5 5 5 4 TRAF-type zinc finger zf-RING_2 PF13639.1 EPS32742.1 - 7.7e-07 28.8 13.9 7.7e-07 28.8 9.6 3.3 2 1 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 EPS32742.1 - 2.9e-06 26.8 8.7 9.2e-06 25.2 6.1 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EPS32742.1 - 3.1e-06 26.9 13.2 3.1e-06 26.9 9.1 2.7 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EPS32742.1 - 2.3e-05 23.9 13.1 2.3e-05 23.9 9.1 3.8 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPS32742.1 - 3e-05 23.6 12.6 3e-05 23.6 8.7 3.4 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EPS32742.1 - 8.2e-05 22.5 13.5 8.2e-05 22.5 9.4 3.9 3 1 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPS32742.1 - 0.00013 21.5 11.4 0.00013 21.5 7.9 3.9 2 1 2 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.11 EPS32742.1 - 0.0087 15.7 14.7 0.16 11.6 1.0 2.9 1 1 1 2 2 2 2 Seven in absentia protein family zf-DNA_Pol PF08996.5 EPS32742.1 - 0.046 13.0 16.9 0.053 12.8 5.5 2.7 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger Het-C PF07217.6 EPS32745.1 - 3.2e-284 943.7 0.0 4.3e-284 943.3 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C Cation_efflux PF01545.16 EPS32746.1 - 1.6e-72 243.9 10.1 1.8e-72 243.8 7.0 1.0 1 0 0 1 1 1 1 Cation efflux family BPD_transp_2 PF02653.11 EPS32746.1 - 0.00028 19.9 1.0 0.00028 19.9 0.7 2.0 2 1 0 2 2 2 1 Branched-chain amino acid transport system / permease component Abhydrolase_6 PF12697.2 EPS32747.1 - 1.9e-12 47.5 2.9 3.3e-12 46.7 2.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPS32747.1 - 1e-05 25.3 0.0 1.9e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPS32747.1 - 0.033 13.7 0.0 0.048 13.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Ank_2 PF12796.2 EPS32748.1 - 9.6e-49 163.6 5.6 5.5e-17 61.8 0.0 8.3 6 1 2 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPS32748.1 - 3.4e-38 129.3 4.0 4.6e-09 36.5 0.0 10.6 9 2 2 11 11 11 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPS32748.1 - 2.4e-36 122.9 7.2 0.00054 20.1 0.0 11.4 10 1 1 11 11 11 8 Ankyrin repeats (many copies) Ank PF00023.25 EPS32748.1 - 4.9e-30 101.8 19.9 8.7e-06 25.2 0.0 12.2 14 0 0 14 14 14 5 Ankyrin repeat Ank_3 PF13606.1 EPS32748.1 - 8.2e-23 78.2 18.2 0.0073 16.4 0.0 12.3 14 0 0 14 14 14 4 Ankyrin repeat PhyH PF05721.8 EPS32749.1 - 1.9e-07 31.3 0.0 1.9e-06 28.0 0.0 2.2 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Zn_clus PF00172.13 EPS32752.1 - 1.6e-07 31.0 8.5 2.5e-07 30.4 5.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 EPS32752.1 - 0.19 11.9 7.0 0.36 11.0 4.9 1.4 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Methyltransf_23 PF13489.1 EPS32753.1 - 5.4e-19 68.4 0.0 9e-19 67.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPS32753.1 - 6.4e-09 36.1 0.0 3.4e-08 33.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS32753.1 - 7.9e-07 29.6 0.0 4.2e-06 27.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPS32753.1 - 2.1e-06 28.1 0.0 5.3e-06 26.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPS32753.1 - 6.9e-06 25.7 0.0 3.7e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EPS32753.1 - 0.0033 16.4 0.0 0.011 14.8 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.13 EPS32753.1 - 0.0039 16.3 0.0 0.15 11.1 0.0 2.6 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EPS32753.1 - 0.015 15.6 0.0 0.048 14.0 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain IBN_N PF03810.14 EPS32754.1 - 4.8e-12 45.6 0.9 2.2e-10 40.3 0.2 3.5 2 1 1 3 3 3 1 Importin-beta N-terminal domain Cnd3 PF12719.2 EPS32754.1 - 0.00078 18.5 0.2 1.2 8.0 0.0 2.7 2 0 0 2 2 2 2 Nuclear condensing complex subunits, C-term domain Cnd1 PF12717.2 EPS32754.1 - 0.0021 17.9 0.1 0.012 15.5 0.0 2.3 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Xpo1 PF08389.7 EPS32754.1 - 0.0034 17.3 0.0 0.085 12.7 0.0 3.2 2 1 0 2 2 2 1 Exportin 1-like protein CAS_CSE1 PF03378.10 EPS32754.1 - 0.0039 15.5 0.0 0.014 13.7 0.0 1.9 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus Adaptin_N PF01602.15 EPS32754.1 - 0.017 13.4 0.0 0.1 10.9 0.0 2.2 2 0 0 2 2 2 0 Adaptin N terminal region HORMA PF02301.13 EPS32755.1 - 6.8e-26 91.0 0.0 8.8e-26 90.6 0.0 1.1 1 0 0 1 1 1 1 HORMA domain WD40 PF00400.27 EPS32757.1 - 1.6e-83 271.8 20.1 2.8e-13 49.1 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat DUF2415 PF10313.4 EPS32757.1 - 3.6e-05 23.3 1.3 1.5 8.5 0.0 5.1 6 0 0 6 6 6 1 Uncharacterised protein domain (DUF2415) TruB_C PF09142.6 EPS32757.1 - 4.4e-05 23.0 0.0 2.2 7.9 0.0 4.2 3 1 1 4 4 4 2 tRNA Pseudouridine synthase II, C terminal Nup160 PF11715.3 EPS32757.1 - 6.7e-05 21.2 4.0 0.025 12.7 0.2 4.1 1 1 1 3 3 3 1 Nucleoporin Nup120/160 PD40 PF07676.7 EPS32757.1 - 0.00027 20.5 5.7 3.4 7.4 0.0 6.1 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 EPS32757.1 - 0.0039 16.3 3.2 4.4 6.3 0.0 4.2 1 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.4 EPS32757.1 - 0.0097 15.2 10.0 2.6 7.4 0.0 5.8 7 0 0 7 7 7 1 Proteasome subunit A N-terminal signature DUF1652 PF07865.6 EPS32757.1 - 0.01 15.4 0.3 38 3.9 0.0 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF1652) Coatomer_WDAD PF04053.9 EPS32757.1 - 0.015 14.0 0.0 0.073 11.8 0.0 1.8 1 1 1 2 2 2 0 Coatomer WD associated region IKI3 PF04762.7 EPS32757.1 - 0.066 11.0 0.2 2.1 6.0 0.0 2.9 1 1 1 2 2 2 0 IKI3 family Peptidase_S29 PF02907.10 EPS32757.1 - 0.07 12.6 0.4 0.4 10.1 0.1 2.2 2 0 0 2 2 2 0 Hepatitis C virus NS3 protease Acetyltransf_7 PF13508.1 EPS32758.1 - 1.2e-07 31.7 0.0 2.6e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPS32758.1 - 8.6e-06 25.7 0.0 2.5e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EPS32758.1 - 1.3e-05 25.0 0.1 6.9e-05 22.7 0.1 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPS32758.1 - 0.0013 18.4 0.0 0.0034 17.0 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EPS32758.1 - 0.0019 18.3 0.0 0.0062 16.6 0.0 2.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EPS32758.1 - 0.031 14.4 0.0 0.068 13.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2036 PF09724.4 EPS32759.1 - 1.6e-12 47.2 0.0 1.1e-11 44.4 0.0 1.9 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) Anp1 PF03452.9 EPS32760.1 - 4.9e-121 403.0 0.0 7.8e-121 402.3 0.0 1.2 1 0 0 1 1 1 1 Anp1 OapA_N PF08525.6 EPS32760.1 - 0.36 10.6 5.6 0.8 9.5 3.9 1.6 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif adh_short PF00106.20 EPS32761.1 - 2e-14 53.8 0.0 3.3e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPS32761.1 - 1.9e-12 47.2 0.0 7.6e-12 45.2 0.0 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EPS32761.1 - 0.00016 21.1 0.0 0.00023 20.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EPS32761.1 - 0.016 14.1 0.0 0.026 13.4 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DapB_N PF01113.15 EPS32761.1 - 0.15 12.0 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus bZIP_1 PF00170.16 EPS32762.1 - 1.6e-08 34.3 9.0 2.3e-08 33.8 6.2 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EPS32762.1 - 1.2e-06 28.2 10.1 1.6e-06 27.8 7.0 1.2 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EPS32762.1 - 9.8e-05 22.5 6.3 0.00015 22.0 4.3 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF2353 PF09789.4 EPS32762.1 - 0.0054 16.0 1.7 0.0069 15.6 1.1 1.1 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) DivIC PF04977.10 EPS32762.1 - 0.19 11.2 0.3 0.37 10.3 0.2 1.4 1 0 0 1 1 1 0 Septum formation initiator tRNA_bind PF01588.15 EPS32763.1 - 1e-21 76.5 0.0 1.6e-19 69.5 0.0 2.6 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 EPS32763.1 - 3.4e-09 37.0 0.0 9.5e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EPS32763.1 - 5.8e-06 26.0 0.0 7e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EPS32763.1 - 0.00025 20.9 0.0 0.00025 20.9 0.0 2.2 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain Cse1 PF08506.5 EPS32763.1 - 0.084 11.4 0.1 0.12 10.8 0.1 1.1 1 0 0 1 1 1 0 Cse1 NPR3 PF03666.8 EPS32763.1 - 0.35 9.3 1.3 0.55 8.7 0.9 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Asp PF00026.18 EPS32764.1 - 8.1e-65 219.1 4.1 9.8e-65 218.8 2.9 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EPS32764.1 - 2.5e-06 27.8 2.0 0.057 13.9 0.6 2.8 2 1 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 EPS32764.1 - 3.5e-06 27.0 0.0 2.2e-05 24.4 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EPS32764.1 - 0.0022 17.5 0.0 0.0064 16.0 0.0 1.9 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal RCR PF12273.3 EPS32765.1 - 0.04 14.4 1.0 0.055 14.0 0.0 1.6 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red DUF3176 PF11374.3 EPS32766.1 - 3.5e-38 129.9 0.2 3.5e-38 129.9 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) RecR PF02132.10 EPS32766.1 - 0.068 12.6 0.1 0.14 11.6 0.1 1.5 1 0 0 1 1 1 0 RecR protein Excalibur PF05901.6 EPS32767.1 - 0.008 16.4 15.3 14 6.0 0.1 5.6 6 0 0 6 6 6 4 Excalibur calcium-binding domain YpzI PF14140.1 EPS32767.1 - 0.29 10.6 11.5 10 5.7 0.0 4.5 5 0 0 5 5 5 0 YpzI-like protein ParA PF10609.4 EPS32768.1 - 2.3e-36 123.5 0.0 6.8e-36 122.0 0.0 1.7 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 EPS32768.1 - 2.8e-17 62.7 0.0 4e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EPS32768.1 - 5.5e-06 26.3 0.0 3.1e-05 23.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 EPS32768.1 - 2.4e-05 23.5 1.2 0.0019 17.3 0.1 2.7 2 1 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.6 EPS32768.1 - 0.00053 19.1 0.0 0.0014 17.7 0.0 1.6 1 1 0 1 1 1 1 ATPase MipZ AAA_25 PF13481.1 EPS32768.1 - 0.0019 17.6 0.0 0.0034 16.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.1 EPS32768.1 - 0.0024 17.5 0.1 0.42 10.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EPS32768.1 - 0.0041 16.3 0.0 0.0078 15.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_19 PF13245.1 EPS32768.1 - 0.014 15.1 0.0 0.34 10.6 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain AAA_30 PF13604.1 EPS32768.1 - 0.019 14.5 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EPS32768.1 - 0.062 12.1 0.0 0.096 11.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.17 EPS32768.1 - 0.084 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 EPS32768.1 - 0.1 12.7 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Fer4_NifH PF00142.13 EPS32768.1 - 0.11 11.6 0.0 0.88 8.7 0.0 2.0 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_5 PF07728.9 EPS32768.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Ras PF00071.17 EPS32768.1 - 0.19 11.0 0.0 0.34 10.2 0.0 1.4 1 0 0 1 1 1 0 Ras family Zn_Tnp_IS1595 PF12760.2 EPS32768.1 - 0.28 11.0 0.1 0.28 11.0 0.1 1.9 2 0 0 2 2 2 0 Transposase zinc-ribbon domain PEMT PF04191.8 EPS32769.1 - 1.3e-56 189.2 15.0 8.4e-37 125.5 0.6 2.9 3 0 0 3 3 3 2 Phospholipid methyltransferase RNase_PH PF01138.16 EPS32770.1 - 4.9e-31 107.7 0.0 9.3e-31 106.8 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 HTH_AsnC-type PF13404.1 EPS32772.1 - 0.035 13.6 0.0 0.069 12.7 0.0 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Kdo_hydroxy PF11004.3 EPS32772.1 - 0.085 11.8 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase Sigma70_r4_2 PF08281.7 EPS32772.1 - 0.13 11.7 0.1 0.39 10.2 0.0 1.8 2 0 0 2 2 2 0 Sigma-70, region 4 ProRS-C_1 PF09180.6 EPS32774.1 - 1.7e-21 75.8 1.0 5e-21 74.4 0.7 1.9 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 EPS32774.1 - 2.6e-21 75.9 0.0 4.1e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EPS32774.1 - 2e-12 46.8 0.6 8.3e-11 41.6 0.0 2.7 3 0 0 3 3 3 1 Anticodon binding domain Cpn60_TCP1 PF00118.19 EPS32775.1 - 1.5e-142 475.6 14.8 1.8e-142 475.4 10.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_int_SAM_1 PF02899.12 EPS32775.1 - 0.045 13.9 0.2 0.41 10.8 0.0 2.5 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain WD40 PF00400.27 EPS32777.1 - 2.4e-22 77.9 2.7 3.1e-06 26.8 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Met_asp_mut_E PF06368.6 EPS32777.1 - 0.031 12.4 0.0 0.064 11.4 0.0 1.4 2 0 0 2 2 2 0 Methylaspartate mutase E chain (MutE) S1 PF00575.18 EPS32778.1 - 1.5e-83 274.9 24.6 1.8e-17 63.1 0.6 11.8 11 0 0 11 11 11 11 S1 RNA binding domain TPR_16 PF13432.1 EPS32778.1 - 4.9e-08 33.4 0.2 0.013 16.2 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EPS32778.1 - 8.3e-07 29.1 0.7 0.5 11.1 0.3 5.4 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 EPS32778.1 - 1.6e-06 28.3 0.0 0.062 13.6 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat Suf PF05843.9 EPS32778.1 - 1.8e-05 24.6 7.9 0.18 11.4 0.1 4.2 2 1 2 4 4 4 3 Suppressor of forked protein (Suf) PPR PF01535.15 EPS32778.1 - 6.6e-05 22.6 0.1 0.63 10.1 0.0 3.1 2 0 0 2 2 2 2 PPR repeat TPR_15 PF13429.1 EPS32778.1 - 0.00029 20.0 0.6 0.13 11.2 0.0 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EPS32778.1 - 0.00031 20.5 0.1 0.00062 19.5 0.0 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 PPR_3 PF13812.1 EPS32778.1 - 0.0024 18.0 0.0 1.5 9.2 0.0 3.0 2 0 0 2 2 2 1 Pentatricopeptide repeat domain TPR_12 PF13424.1 EPS32778.1 - 0.003 17.4 0.2 0.27 11.2 0.1 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat PPR_2 PF13041.1 EPS32778.1 - 0.018 14.9 0.2 12 5.9 0.1 2.9 3 0 0 3 3 3 0 PPR repeat family SDA1 PF05285.7 EPS32778.1 - 5.4 6.1 37.5 0.84 8.8 12.0 2.9 3 0 0 3 3 3 0 SDA1 GDPD_2 PF13653.1 EPS32779.1 - 0.0013 18.8 1.0 0.0078 16.3 0.5 2.3 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family GDPD PF03009.12 EPS32779.1 - 0.084 12.3 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family UreD PF01774.12 EPS32780.1 - 1.1e-56 191.6 0.0 2.2e-56 190.6 0.0 1.5 1 1 0 1 1 1 1 UreD urease accessory protein STAG PF08514.6 EPS32781.1 - 4.2e-34 116.7 0.1 9.9e-34 115.5 0.1 1.7 1 0 0 1 1 1 1 STAG domain CobD_Cbib PF03186.8 EPS32781.1 - 0.24 10.4 1.4 0.3 10.0 0.1 1.7 2 0 0 2 2 2 0 CobD/Cbib protein Arm PF00514.18 EPS32782.1 - 5.2e-92 298.8 12.1 1.7e-13 49.7 0.1 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EPS32782.1 - 3.6e-23 81.6 0.5 2.7e-09 37.1 0.0 5.7 1 1 5 6 6 6 5 HEAT repeats IBB PF01749.15 EPS32782.1 - 5.4e-21 74.5 1.9 9.7e-21 73.7 1.3 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 EPS32782.1 - 1e-19 70.4 10.2 1.3e-09 38.2 0.1 6.1 5 1 2 7 7 7 3 HEAT-like repeat HEAT PF02985.17 EPS32782.1 - 8.4e-19 65.9 0.7 4.3e-06 26.3 0.0 7.1 8 0 0 8 8 8 3 HEAT repeat Arm_2 PF04826.8 EPS32782.1 - 4.1e-11 42.4 0.0 0.00046 19.3 0.0 4.0 2 1 2 4 4 4 2 Armadillo-like Adaptin_N PF01602.15 EPS32782.1 - 5.1e-05 21.7 0.0 0.0058 15.0 0.0 2.4 1 1 1 2 2 2 2 Adaptin N terminal region V-ATPase_H_C PF11698.3 EPS32782.1 - 0.00022 21.1 0.0 1.3 8.9 0.0 4.4 3 2 0 4 4 4 1 V-ATPase subunit H Proteasom_PSMB PF10508.4 EPS32782.1 - 0.0037 15.6 0.0 0.36 9.0 0.0 2.9 2 1 1 3 3 3 2 Proteasome non-ATPase 26S subunit Glycos_trans_3N PF02885.12 EPS32782.1 - 0.0059 16.1 0.0 17 5.0 0.0 3.5 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain HEAT_PBS PF03130.11 EPS32782.1 - 0.19 12.3 7.5 1.2 9.7 0.0 4.5 5 0 0 5 5 5 0 PBS lyase HEAT-like repeat POT1 PF02765.12 EPS32783.1 - 3e-17 62.8 0.0 8e-16 58.2 0.0 2.2 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 tRNA_anti-codon PF01336.20 EPS32783.1 - 0.048 13.5 0.0 0.96 9.3 0.0 2.7 3 0 0 3 3 3 0 OB-fold nucleic acid binding domain DUF3127 PF11325.3 EPS32783.1 - 0.11 12.4 0.0 0.66 10.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3127) zf-CCCH_2 PF14608.1 EPS32784.1 - 0.022 14.7 0.3 0.022 14.7 0.2 2.8 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type TRAP_alpha PF03896.11 EPS32785.1 - 2.3e-15 56.3 0.0 3.2e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DcpS_C PF11969.3 EPS32786.1 - 8.9e-19 67.8 2.0 5e-18 65.4 1.4 2.0 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EPS32786.1 - 1.9e-15 57.1 2.3 7.1e-15 55.3 1.6 1.9 1 1 0 1 1 1 1 HIT domain HA2 PF04408.18 EPS32787.1 - 1.4e-19 70.0 0.5 3.9e-19 68.5 0.0 2.0 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EPS32787.1 - 3.2e-17 62.3 0.0 7.4e-17 61.2 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EPS32787.1 - 1.4e-12 47.2 0.0 4.5e-12 45.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RWD PF05773.17 EPS32787.1 - 1.9e-11 43.8 0.0 4.3e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 RWD domain DEAD PF00270.24 EPS32787.1 - 1.5e-09 37.5 0.1 2.7e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_29 PF13555.1 EPS32787.1 - 0.0034 16.8 0.0 0.007 15.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DND1_DSRM PF14709.1 EPS32787.1 - 0.0038 17.4 0.1 0.013 15.8 0.0 1.9 1 0 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 T2SE PF00437.15 EPS32787.1 - 0.0039 16.1 0.0 0.0084 15.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 EPS32787.1 - 0.004 17.2 1.1 0.021 14.9 0.7 2.2 1 1 0 1 1 1 1 AAA domain PhoH PF02562.11 EPS32787.1 - 0.026 13.7 0.0 0.052 12.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein KaiC PF06745.8 EPS32787.1 - 0.045 12.8 0.1 0.084 11.9 0.0 1.3 1 0 0 1 1 1 0 KaiC ResIII PF04851.10 EPS32787.1 - 0.051 13.4 0.0 0.18 11.5 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Podovirus_Gp16 PF05894.7 EPS32787.1 - 0.059 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Podovirus DNA encapsidation protein (Gp16) UBA PF00627.26 EPS32787.1 - 0.065 13.0 0.0 4 7.4 0.0 2.7 2 0 0 2 2 2 0 UBA/TS-N domain Rap1_C PF11626.3 EPS32787.1 - 0.067 13.0 0.0 0.66 9.8 0.0 2.5 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Zot PF05707.7 EPS32787.1 - 0.092 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_23 PF13476.1 EPS32787.1 - 0.19 12.0 0.0 0.19 12.0 0.0 1.7 2 0 0 2 2 1 0 AAA domain Cyclin_N PF00134.18 EPS32788.1 - 9.2e-40 135.1 0.0 1.6e-39 134.3 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EPS32788.1 - 4.7e-31 107.1 0.1 9.7e-31 106.1 0.1 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Zn_clus PF00172.13 EPS32790.1 - 0.00037 20.3 10.9 0.0007 19.4 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.5 EPS32790.1 - 0.043 13.0 0.0 0.15 11.2 0.0 1.9 1 0 0 1 1 1 0 Histone chaperone domain CHZ RNA_pol_Rpc4 PF05132.9 EPS32792.1 - 1.2e-30 106.1 0.0 1.2e-30 106.1 0.0 3.2 3 1 1 4 4 4 1 RNA polymerase III RPC4 FCP1_C PF09309.5 EPS32794.1 - 0.078 12.2 0.4 0.087 12.1 0.3 1.0 1 0 0 1 1 1 0 FCP1, C-terminal DUF1418 PF07214.7 EPS32795.1 - 0.055 13.0 0.0 0.067 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) CRCB PF02537.10 EPS32796.1 - 1.9e-28 98.7 29.1 8.4e-20 70.8 4.7 3.8 3 1 0 3 3 3 2 CrcB-like protein MatE PF01554.13 EPS32796.1 - 0.018 14.6 0.7 0.018 14.6 0.5 2.8 3 0 0 3 3 3 0 MatE UPRTase PF14681.1 EPS32797.1 - 4.5e-72 241.5 0.0 5.5e-72 241.3 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EPS32797.1 - 7.5e-05 22.4 0.3 0.00021 21.0 0.2 1.8 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Fungal_trans PF04082.13 EPS32798.1 - 2.5e-21 75.7 3.4 4.1e-21 75.0 2.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 EPS32798.1 - 4.5e-07 29.8 15.2 9.9e-05 22.4 4.0 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EPS32798.1 - 5.8e-05 23.1 13.3 0.0039 17.4 3.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EPS32798.1 - 0.0002 21.4 14.4 0.034 14.5 4.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EPS32798.1 - 0.53 10.2 4.2 15 5.6 0.1 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger RasGEF PF00617.14 EPS32802.1 - 4.1e-63 212.5 0.0 7.5e-63 211.6 0.0 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EPS32802.1 - 1.7e-28 98.7 0.6 3.5e-28 97.7 0.4 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 EPS32802.1 - 1.1e-15 56.7 0.1 1.1e-15 56.7 0.1 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EPS32802.1 - 6.6e-14 51.2 0.1 2.4e-13 49.4 0.1 2.1 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EPS32802.1 - 1.3e-10 40.6 0.0 2.8e-10 39.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 EPS32802.1 - 0.0017 18.1 0.0 0.004 16.9 0.0 1.6 1 0 0 1 1 1 1 WW domain JAB PF01398.16 EPS32803.1 - 2.3e-28 98.1 0.0 5.5e-28 96.9 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EPS32803.1 - 3.1e-07 29.9 0.0 5.6e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain MAP65_ASE1 PF03999.7 EPS32804.1 - 1.3e-76 258.6 13.5 3.2e-76 257.2 6.3 2.7 2 1 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) Prominin PF05478.6 EPS32804.1 - 0.015 12.8 1.0 0.026 12.1 0.7 1.3 1 0 0 1 1 1 0 Prominin Abhydrolase_6 PF12697.2 EPS32805.1 - 2.3e-10 40.7 0.0 3.5e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPS32805.1 - 6.9e-10 38.8 0.0 1e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.5 EPS32805.1 - 0.022 13.6 0.0 0.18 10.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Lipase_3 PF01764.20 EPS32805.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_8 PF06259.7 EPS32805.1 - 0.26 10.7 0.9 8.4 5.8 0.1 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase CTDII PF01556.13 EPS32806.1 - 1.2e-23 82.8 0.2 2.1e-20 72.3 0.0 2.8 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 EPS32806.1 - 4.1e-22 77.6 1.7 7.3e-22 76.8 1.2 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EPS32806.1 - 4.5e-13 49.0 17.7 7.7e-13 48.2 12.2 1.4 1 0 0 1 1 1 1 DnaJ central domain Fork_head_N PF08430.7 EPS32806.1 - 0.72 10.2 7.0 1.3 9.4 4.9 1.3 1 0 0 1 1 1 0 Forkhead N-terminal region GCC2_GCC3 PF07699.8 EPS32806.1 - 1.4 8.5 14.0 0.72 9.4 3.4 2.5 2 0 0 2 2 2 0 GCC2 and GCC3 tRNA-synt_1c PF00749.16 EPS32807.1 - 2.7e-94 315.3 0.0 3.4e-94 315.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Fmp27 PF10344.4 EPS32808.1 - 7.5e-236 784.9 0.0 7.5e-236 784.9 0.0 3.6 5 0 0 5 5 5 1 Mitochondrial protein from FMP27 Apt1 PF10351.4 EPS32808.1 - 5.3e-167 556.3 0.0 5.3e-167 556.3 0.0 3.7 4 0 0 4 4 4 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 EPS32808.1 - 6.3e-153 509.6 8.3 1.5e-152 508.3 5.7 1.7 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 EPS32808.1 - 2e-56 190.0 0.6 4.4e-56 189.0 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_GFWDK PF10347.4 EPS32808.1 - 2.1e-51 173.9 0.0 8.3e-51 171.9 0.0 2.2 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_SW PF10305.4 EPS32808.1 - 1.2e-30 105.9 0.0 7.7e-30 103.3 0.0 2.5 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Osmo_CC PF08946.5 EPS32809.1 - 0.0023 17.9 0.2 0.0032 17.4 0.1 1.2 1 0 0 1 1 1 1 Osmosensory transporter coiled coil HR1 PF02185.11 EPS32809.1 - 0.092 12.5 0.3 0.14 11.9 0.2 1.3 1 0 0 1 1 1 0 Hr1 repeat TauE PF01925.14 EPS32809.1 - 0.13 11.7 3.7 0.18 11.2 2.5 1.1 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE RRM_6 PF14259.1 EPS32810.1 - 1.7e-16 59.9 0.0 2.6e-16 59.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPS32810.1 - 2.1e-14 52.8 0.0 3.8e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS32810.1 - 9.9e-06 25.3 0.0 1.6e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sec2p PF06428.6 EPS32812.1 - 3.3e-09 36.4 12.7 3.3e-09 36.4 8.8 2.1 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p Jnk-SapK_ap_N PF09744.4 EPS32812.1 - 0.0032 17.4 11.6 0.072 13.0 4.7 2.1 2 0 0 2 2 2 2 JNK_SAPK-associated protein-1 HSBP1 PF06825.7 EPS32812.1 - 0.027 14.0 0.6 3 7.5 0.0 2.3 2 0 0 2 2 2 0 Heat shock factor binding protein 1 HOOK PF05622.7 EPS32812.1 - 0.051 11.3 0.2 0.051 11.3 0.2 2.1 2 0 0 2 2 2 0 HOOK protein Nicastrin PF05450.10 EPS32812.1 - 0.06 12.5 0.1 0.11 11.7 0.1 1.4 1 0 0 1 1 1 0 Nicastrin Rtf2 PF04641.7 EPS32812.1 - 0.11 11.6 0.1 0.11 11.6 0.0 2.0 2 0 0 2 2 2 0 Rtf2 RING-finger ECSIT PF06239.6 EPS32812.1 - 0.19 10.5 1.7 0.36 9.6 1.2 1.4 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway IncA PF04156.9 EPS32812.1 - 0.51 9.8 18.1 1.4 8.5 7.5 2.1 1 1 1 2 2 2 0 IncA protein Atg14 PF10186.4 EPS32812.1 - 0.69 8.7 18.1 0.55 9.1 0.6 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 ADIP PF11559.3 EPS32812.1 - 0.86 9.4 16.0 0.4 10.5 0.1 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding AATF-Che1 PF13339.1 EPS32812.1 - 0.95 9.6 13.7 1.1 9.4 1.0 2.2 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor SlyX PF04102.7 EPS32812.1 - 1 9.8 10.2 1.7 9.0 0.1 3.4 2 1 1 3 3 3 0 SlyX Vac_Fusion PF02346.11 EPS32812.1 - 1.8 8.0 5.6 3.6 7.0 1.4 2.3 2 0 0 2 2 2 0 Chordopoxvirus fusion protein HAUS6_N PF14661.1 EPS32812.1 - 1.9 7.7 12.3 2.3 7.5 3.7 2.1 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus FlaC_arch PF05377.6 EPS32812.1 - 3.1 7.7 5.5 19 5.2 0.0 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) HR1 PF02185.11 EPS32812.1 - 3.8 7.3 14.5 14 5.5 5.3 3.4 2 2 1 3 3 3 0 Hr1 repeat CDC37_N PF03234.9 EPS32812.1 - 4.8 7.4 7.1 24 5.1 0.1 2.1 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding Spc7 PF08317.6 EPS32812.1 - 8.1 4.9 11.2 2 7.0 0.1 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein GFO_IDH_MocA PF01408.17 EPS32813.1 - 6.2e-14 52.5 0.0 1e-13 51.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EPS32813.1 - 9.5e-05 22.1 0.0 0.00017 21.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain ResIII PF04851.10 EPS32813.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Ribosomal_L32e PF01655.13 EPS32814.1 - 2e-50 169.4 1.2 2.6e-50 169.0 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 PseudoU_synth_2 PF00849.17 EPS32815.1 - 1.5e-26 93.1 0.0 2.4e-26 92.5 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase GFA PF04828.9 EPS32815.1 - 0.0093 15.8 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme 4HBT PF03061.17 EPS32816.1 - 1.2e-14 54.1 0.0 1.7e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.1 EPS32816.1 - 2.8e-06 27.7 0.0 3.7e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.12 EPS32816.1 - 0.00098 18.1 0.1 0.0016 17.4 0.1 1.4 1 0 0 1 1 1 1 Acyl-ACP thioesterase TRAP-gamma PF07074.7 EPS32818.1 - 1.9 8.0 4.8 0.25 10.8 0.2 1.7 2 0 0 2 2 2 0 Translocon-associated protein, gamma subunit (TRAP-gamma) B-block_TFIIIC PF04182.7 EPS32819.1 - 2.3e-19 68.9 0.1 7.1e-19 67.4 0.0 1.9 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC MarR_2 PF12802.2 EPS32819.1 - 0.00086 18.9 0.0 0.0054 16.3 0.0 2.4 1 0 0 1 1 1 1 MarR family MarR PF01047.17 EPS32819.1 - 0.0013 18.3 0.0 0.0048 16.5 0.0 2.0 1 0 0 1 1 1 1 MarR family HTH_36 PF13730.1 EPS32819.1 - 0.17 12.0 0.0 33 4.7 0.0 2.8 2 0 0 2 2 2 0 Helix-turn-helix domain RNA_pol_Rpc34 PF05158.7 EPS32819.1 - 0.23 10.6 0.0 1.4 7.9 0.0 2.2 3 0 0 3 3 3 0 RNA polymerase Rpc34 subunit UQ_con PF00179.21 EPS32820.1 - 1.9e-21 75.9 0.0 3.3e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EPS32820.1 - 0.013 15.4 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 RWD domain zf-DHHC PF01529.15 EPS32821.1 - 1.3e-40 138.6 2.0 1.3e-40 138.6 1.4 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase Rhomboid PF01694.17 EPS32822.1 - 1.1e-34 119.5 9.8 1.1e-34 119.5 6.8 1.8 2 0 0 2 2 2 1 Rhomboid family DUF3317 PF11779.3 EPS32823.1 - 3.5e-18 64.7 3.4 4.8e-18 64.3 2.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) Kinetochor_Ybp2 PF08568.5 EPS32825.1 - 4.9e-149 497.4 0.1 5.9e-149 497.2 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin PLDc_2 PF13091.1 EPS32827.1 - 2e-12 46.9 0.0 1.8e-05 24.4 0.0 3.6 3 1 0 3 3 3 2 PLD-like domain PLDc PF00614.17 EPS32827.1 - 1.6e-11 43.6 1.1 4.6e-05 23.0 0.2 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif Cyanate_lyase PF02560.9 EPS32828.1 - 1.2e-31 108.0 0.0 1.7e-31 107.5 0.0 1.2 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_3 PF01381.17 EPS32828.1 - 0.0075 16.0 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 EPS32828.1 - 0.0088 16.2 0.0 0.014 15.6 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Carb_kinase PF01256.12 EPS32829.1 - 0.045 13.0 0.0 0.045 13.0 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate kinase Ndc1_Nup PF09531.5 EPS32831.1 - 0.045 12.1 12.7 0.073 11.4 8.8 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DNA_pol_B PF00136.16 EPS32832.1 - 8.6e-145 483.0 2.6 1.2e-144 482.6 1.8 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EPS32832.1 - 8.3e-81 271.3 0.0 1.8e-80 270.2 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EPS32832.1 - 1.1e-23 82.9 5.1 2.8e-23 81.7 3.5 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 EPS32832.1 - 0.00016 21.5 0.3 0.00071 19.4 0.2 2.2 1 1 0 1 1 1 1 RNase_H superfamily C1_1 PF00130.17 EPS32832.1 - 0.014 15.1 1.0 0.014 15.1 0.7 2.5 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DNA_pol_B_exo2 PF10108.4 EPS32832.1 - 0.047 13.2 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DUF2614 PF11023.3 EPS32832.1 - 0.12 12.1 0.1 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2614) Pkinase PF00069.20 EPS32833.1 - 1.1e-40 139.4 0.1 2.7e-26 92.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPS32833.1 - 1.4e-18 66.8 0.0 7e-17 61.3 0.0 2.9 1 1 0 1 1 1 1 Protein tyrosine kinase Acyl-CoA_dh_1 PF00441.19 EPS32834.1 - 7.3e-31 107.2 0.4 1e-30 106.8 0.3 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EPS32834.1 - 3e-22 79.3 0.0 7.5e-22 78.0 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EPS32834.1 - 1.1e-21 76.0 0.8 2.1e-21 75.1 0.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EPS32834.1 - 0.00064 19.9 0.4 0.0015 18.8 0.2 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Syja_N PF02383.13 EPS32835.1 - 3.9e-92 308.4 0.0 7.3e-92 307.5 0.0 1.4 1 0 0 1 1 1 1 SacI homology domain DUF2454 PF10521.4 EPS32836.1 - 5.4e-85 284.8 1.3 8.1e-85 284.2 0.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) PolyA_pol PF01743.15 EPS32837.1 - 4.3e-22 78.6 1.3 1.2e-21 77.1 0.9 1.8 1 1 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EPS32837.1 - 3.2e-09 36.2 0.0 8.6e-09 34.8 0.0 1.8 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 EPS32837.1 - 0.015 15.0 0.0 0.04 13.7 0.0 1.7 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative TRAPPC-Trs85 PF12739.2 EPS32838.1 - 5.9e-121 404.0 0.1 8.4e-121 403.4 0.0 1.1 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Snf7 PF03357.16 EPS32839.1 - 3.4e-17 62.3 14.5 3.4e-17 62.3 10.0 2.0 1 1 1 2 2 2 1 Snf7 Phage_hub_GP28 PF11110.3 EPS32839.1 - 0.076 12.7 0.1 0.2 11.3 0.1 1.8 1 1 1 2 2 2 0 Baseplate hub distal subunit MbeD_MobD PF04899.7 EPS32839.1 - 0.2 11.6 4.8 0.51 10.2 0.0 3.3 3 0 0 3 3 3 0 MbeD/MobD like DUF3461 PF11944.3 EPS32839.1 - 0.49 10.2 8.7 0.047 13.5 1.0 2.8 2 2 1 3 3 3 0 Protein of unknown function (DUF3461) MutS_III PF05192.13 EPS32839.1 - 0.59 9.8 6.1 1.7 8.4 4.1 1.9 1 1 0 1 1 1 0 MutS domain III HHH_2 PF12826.2 EPS32839.1 - 1.5 8.7 3.9 20 5.1 0.1 3.2 2 1 1 3 3 3 0 Helix-hairpin-helix motif Baculo_PEP_C PF04513.7 EPS32839.1 - 3.2 7.5 14.7 2.2 8.0 4.0 3.1 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 EPS32839.1 - 7.6 6.8 11.4 27 5.1 3.0 3.8 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein zf-C3HC4_2 PF13923.1 EPS32840.1 - 5.1e-08 32.8 19.7 1.1e-07 31.7 9.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPS32840.1 - 2.4e-07 30.3 12.8 2.4e-07 30.3 8.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPS32840.1 - 3.3e-07 29.9 17.1 9.3e-07 28.4 9.0 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 EPS32840.1 - 5.6e-07 29.2 18.5 1.2e-06 28.2 9.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EPS32840.1 - 1.2e-06 28.0 15.1 1.5e-06 27.8 6.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EPS32840.1 - 2.2e-06 27.3 5.7 4.9e-06 26.2 4.0 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein SAP PF02037.22 EPS32840.1 - 0.00011 21.5 0.0 0.00022 20.6 0.0 1.5 1 0 0 1 1 1 1 SAP domain zf-C3HC4_4 PF15227.1 EPS32840.1 - 0.00014 21.6 15.7 0.00017 21.4 8.8 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EPS32840.1 - 0.0017 18.4 5.7 0.0017 18.4 3.9 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger Mob_synth_C PF06463.8 EPS32840.1 - 0.0081 15.8 4.8 0.021 14.5 3.3 1.7 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C zf-RING_UBOX PF13445.1 EPS32840.1 - 0.011 15.4 10.5 0.011 15.4 7.3 2.4 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.1 EPS32840.1 - 0.058 12.9 12.7 0.074 12.6 7.0 2.4 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Sgf11 PF08209.6 EPS32840.1 - 0.078 12.3 0.2 0.078 12.3 0.1 2.8 3 1 1 4 4 3 0 Sgf11 (transcriptional regulation protein) Rad50_zn_hook PF04423.9 EPS32840.1 - 0.47 9.9 7.9 1.2 8.6 0.0 3.4 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-Apc11 PF12861.2 EPS32840.1 - 1.2 9.0 7.2 0.13 12.0 2.0 1.7 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zinc-ribbons_6 PF07191.7 EPS32840.1 - 1.8 8.3 8.9 21 4.9 0.0 2.6 2 0 0 2 2 2 0 zinc-ribbons Prok-RING_1 PF14446.1 EPS32840.1 - 3.8 7.3 10.9 16 5.3 0.0 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 CDC27 PF09507.5 EPS32841.1 - 7.7e-108 361.4 24.9 9.2e-108 361.2 17.2 1.0 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 DUF1237 PF06824.6 EPS32842.1 - 1.7e-180 600.1 0.6 2e-180 599.9 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) Pex2_Pex12 PF04757.9 EPS32843.1 - 1.5e-57 194.6 4.8 1.9e-57 194.3 3.3 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 EPS32843.1 - 3e-06 27.0 3.0 5.2e-06 26.2 2.1 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EPS32843.1 - 6.2e-06 26.1 3.3 6.2e-06 26.1 2.3 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPS32843.1 - 0.0037 17.0 2.3 0.0037 17.0 1.6 1.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EPS32843.1 - 0.0037 16.8 2.5 0.0066 16.0 1.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPS32843.1 - 0.048 13.3 1.7 0.084 12.5 1.2 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Oligomerisation PF02410.10 EPS32844.1 - 9.6e-06 25.5 0.1 0.00012 22.0 0.0 2.6 2 1 0 2 2 2 1 Oligomerisation domain NMD3 PF04981.8 EPS32845.1 - 3.8e-76 255.3 7.7 3.8e-76 255.3 5.3 1.5 2 0 0 2 2 2 1 NMD3 family HypA PF01155.14 EPS32845.1 - 7.8 6.2 9.9 11 5.7 1.0 2.8 2 1 1 3 3 3 0 Hydrogenase expression/synthesis hypA family RRM_5 PF13893.1 EPS32846.1 - 0.019 14.8 0.0 0.042 13.7 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPS32846.1 - 0.024 14.2 0.0 0.32 10.6 0.0 2.3 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Mito_carr PF00153.22 EPS32847.1 - 1e-62 207.8 3.7 1.4e-20 72.7 0.1 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein WAC_Acf1_DNA_bd PF10537.4 EPS32848.1 - 2.2e-41 140.1 0.1 7e-41 138.5 0.1 1.9 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 EPS32848.1 - 3.6e-17 61.8 1.6 7.7e-17 60.8 1.1 1.6 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 EPS32848.1 - 1.8e-10 40.3 0.1 4.3e-10 39.0 0.1 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM1 PF15612.1 EPS32848.1 - 0.00018 21.2 0.1 0.0026 17.5 0.0 2.8 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 DUF4094 PF13334.1 EPS32848.1 - 1 9.7 5.8 1.5 9.2 2.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Alg6_Alg8 PF03155.10 EPS32849.1 - 1.6e-139 465.7 34.5 2.1e-139 465.4 23.9 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Lectin_leg-like PF03388.8 EPS32851.1 - 6.3e-27 94.1 0.0 1e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family FAM196 PF15265.1 EPS32851.1 - 0.0077 15.5 12.1 0.01 15.1 8.4 1.1 1 0 0 1 1 1 1 FAM196 family SPX PF03105.14 EPS32851.1 - 2.1 8.0 9.3 0.27 10.9 3.3 1.6 2 0 0 2 2 2 0 SPX domain EMP24_GP25L PF01105.19 EPS32851.1 - 2.2 7.9 6.0 43 3.7 4.1 2.4 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Pkinase PF00069.20 EPS32852.1 - 1.2e-16 60.6 0.0 1.8e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS32852.1 - 1.1e-05 24.6 0.0 0.00031 19.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPS32852.1 - 0.047 13.4 0.1 0.082 12.6 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family PHD PF00628.24 EPS32853.1 - 4e-20 71.2 19.3 1.7e-10 40.3 6.6 2.7 2 1 0 2 2 2 2 PHD-finger PHD_2 PF13831.1 EPS32853.1 - 0.0047 16.1 2.4 0.0047 16.1 1.6 3.6 3 1 0 3 3 3 2 PHD-finger zf-PHD-like PF15446.1 EPS32853.1 - 0.0085 15.4 6.8 0.36 10.1 0.8 2.6 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 EPS32853.1 - 0.009 15.7 10.2 0.14 11.9 0.3 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.1 EPS32853.1 - 0.01 15.9 8.6 0.079 13.1 2.4 2.5 2 0 0 2 2 2 0 PHD-like zinc-binding domain Prok-RING_1 PF14446.1 EPS32853.1 - 0.013 15.2 12.1 0.016 14.9 0.7 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-HC5HC2H_2 PF13832.1 EPS32853.1 - 0.087 12.8 4.4 0.36 10.8 0.5 2.5 2 0 0 2 2 2 0 PHD-zinc-finger like domain TAFII55_N PF04658.8 EPS32853.1 - 0.17 11.3 0.0 6.8 6.1 0.0 2.4 2 0 0 2 2 2 0 TAFII55 protein conserved region HypA PF01155.14 EPS32853.1 - 7.4 6.2 8.3 4.5 6.9 0.1 2.5 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Peptidase_M24 PF00557.19 EPS32854.1 - 7.6e-11 41.9 0.5 9.8e-11 41.6 0.3 1.3 1 1 0 1 1 1 1 Metallopeptidase family M24 Exo_endo_phos PF03372.18 EPS32856.1 - 3.4e-11 43.5 0.4 4.3e-11 43.2 0.3 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EPS32856.1 - 0.0055 16.2 0.0 0.011 15.3 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase SNF5 PF04855.7 EPS32858.1 - 1.5e-76 257.1 0.5 2.4e-76 256.4 0.3 1.3 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 HEAT_2 PF13646.1 EPS32859.1 - 3.4e-08 33.6 9.7 5e-05 23.5 0.0 5.7 3 2 1 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 EPS32859.1 - 0.00026 21.3 3.3 0.023 15.1 0.0 4.5 3 0 0 3 3 3 1 HEAT-like repeat HEAT PF02985.17 EPS32859.1 - 0.0006 19.6 13.0 0.073 13.1 0.0 6.6 6 0 0 6 6 6 1 HEAT repeat RIX1 PF08167.7 EPS32859.1 - 0.0032 17.1 0.2 6.4 6.4 0.0 3.9 4 0 0 4 4 4 2 rRNA processing/ribosome biogenesis MFS_1 PF07690.11 EPS32860.1 - 1.2e-38 132.7 43.4 1.2e-38 132.7 30.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 EPS32860.1 - 0.012 13.7 5.5 0.83 7.6 3.6 2.6 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family AAA PF00004.24 EPS32861.1 - 4.9e-98 324.4 0.0 7.6e-48 162.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EPS32861.1 - 6.4e-20 70.9 0.6 2.4e-19 69.0 0.4 2.1 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 EPS32861.1 - 4.7e-14 52.6 0.0 1.3e-07 31.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EPS32861.1 - 4.5e-13 48.7 0.0 1.5e-05 24.1 0.0 2.8 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EPS32861.1 - 5.3e-13 49.0 0.0 5.2e-06 26.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EPS32861.1 - 1.6e-11 44.0 0.8 5.4e-06 26.1 0.0 4.1 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EPS32861.1 - 1.7e-11 45.0 0.0 0.00032 21.4 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EPS32861.1 - 1.8e-11 44.2 0.4 0.0024 18.0 0.1 4.3 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EPS32861.1 - 2.8e-11 43.7 0.3 0.0008 19.4 0.0 3.9 3 2 1 4 4 3 2 AAA ATPase domain TIP49 PF06068.8 EPS32861.1 - 4.7e-09 35.4 0.0 0.001 17.8 0.0 2.7 2 0 0 2 2 2 2 TIP49 C-terminus AAA_14 PF13173.1 EPS32861.1 - 6.7e-08 32.4 0.0 0.0031 17.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EPS32861.1 - 8e-08 31.9 1.5 0.0039 16.8 0.0 3.0 2 0 0 2 2 2 2 Part of AAA domain IstB_IS21 PF01695.12 EPS32861.1 - 8.2e-08 31.8 0.0 0.0064 15.9 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein CDC48_2 PF02933.12 EPS32861.1 - 1.9e-07 30.6 0.0 4.7e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_25 PF13481.1 EPS32861.1 - 2.2e-07 30.4 6.3 0.095 12.0 0.0 4.7 3 2 1 5 5 4 2 AAA domain Zeta_toxin PF06414.7 EPS32861.1 - 2.6e-07 29.9 0.0 0.0054 15.8 0.0 2.8 3 0 0 3 3 2 2 Zeta toxin RNA_helicase PF00910.17 EPS32861.1 - 4.8e-07 29.9 0.0 0.023 14.8 0.0 2.9 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.16 EPS32861.1 - 6e-07 28.8 0.7 0.031 13.4 0.1 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI KaiC PF06745.8 EPS32861.1 - 1.6e-06 27.4 0.8 0.46 9.5 0.0 3.4 2 1 1 3 3 3 2 KaiC ResIII PF04851.10 EPS32861.1 - 3.6e-06 26.9 0.0 0.0039 17.0 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_18 PF13238.1 EPS32861.1 - 3.8e-06 27.2 0.0 0.066 13.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.1 EPS32861.1 - 7.2e-06 25.7 0.3 0.16 11.5 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.1 EPS32861.1 - 1.2e-05 25.3 0.0 0.18 11.7 0.0 2.8 3 0 0 3 3 2 2 AAA domain DUF815 PF05673.8 EPS32861.1 - 1.3e-05 24.2 0.0 0.015 14.2 0.0 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Parvo_NS1 PF01057.12 EPS32861.1 - 2.5e-05 23.3 0.1 0.084 11.7 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Arch_ATPase PF01637.13 EPS32861.1 - 2.7e-05 24.0 0.1 6.7 6.3 0.0 4.1 2 2 2 4 4 4 0 Archaeal ATPase Vps4_C PF09336.5 EPS32861.1 - 3e-05 23.8 0.0 0.00018 21.3 0.0 2.2 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Sigma54_activat PF00158.21 EPS32861.1 - 3.3e-05 23.4 0.1 0.34 10.3 0.0 3.3 2 2 0 2 2 2 2 Sigma-54 interaction domain PhoH PF02562.11 EPS32861.1 - 8.3e-05 21.9 0.4 0.31 10.2 0.0 2.7 2 0 0 2 2 2 2 PhoH-like protein Sigma54_activ_2 PF14532.1 EPS32861.1 - 8.7e-05 22.5 0.0 0.37 10.8 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain NACHT PF05729.7 EPS32861.1 - 0.00021 21.0 0.1 0.63 9.6 0.0 3.5 3 1 1 4 4 3 1 NACHT domain ABC_tran PF00005.22 EPS32861.1 - 0.00024 21.3 0.0 0.68 10.2 0.0 3.4 2 1 0 2 2 2 1 ABC transporter Bac_DnaA PF00308.13 EPS32861.1 - 0.00025 20.7 0.0 1.1 8.8 0.0 3.1 3 0 0 3 3 3 2 Bacterial dnaA protein AAA_3 PF07726.6 EPS32861.1 - 0.0004 19.9 0.0 0.94 9.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 EPS32861.1 - 0.00051 19.1 0.0 0.61 9.0 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 EPS32861.1 - 0.00054 19.5 0.0 0.67 9.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.1 EPS32861.1 - 0.0011 18.6 0.0 1.1 8.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain NTPase_1 PF03266.10 EPS32861.1 - 0.0023 17.6 0.9 1 9.0 0.0 4.1 5 0 0 5 5 3 1 NTPase NB-ARC PF00931.17 EPS32861.1 - 0.0048 15.7 1.6 0.84 8.4 0.0 2.9 4 0 0 4 4 3 1 NB-ARC domain Viral_helicase1 PF01443.13 EPS32861.1 - 0.0055 16.2 0.0 0.55 9.7 0.0 2.7 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase Zot PF05707.7 EPS32861.1 - 0.021 14.2 0.6 15 4.9 0.1 4.2 4 1 0 4 4 4 0 Zonular occludens toxin (Zot) KAP_NTPase PF07693.9 EPS32861.1 - 0.023 13.7 0.5 1.4 7.8 0.0 3.0 2 2 1 4 4 4 0 KAP family P-loop domain IPT PF01745.11 EPS32861.1 - 0.026 13.7 0.0 2 7.5 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase AAA_10 PF12846.2 EPS32861.1 - 0.045 13.1 0.6 7.3 5.9 0.0 3.6 3 1 0 4 4 4 0 AAA-like domain UFD1 PF03152.9 EPS32861.1 - 0.091 11.8 0.0 3.3 6.8 0.0 2.4 1 1 0 1 1 1 0 Ubiquitin fusion degradation protein UFD1 SKI PF01202.17 EPS32861.1 - 0.093 12.5 0.0 9.2 6.1 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase UPF0079 PF02367.12 EPS32861.1 - 0.13 11.8 0.1 16 5.1 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PEX11 PF05648.9 EPS32862.1 - 9.5e-15 54.4 0.6 8.3e-12 44.8 0.0 2.1 2 0 0 2 2 2 2 Peroxisomal biogenesis factor 11 (PEX11) Peripla_BP_3 PF13377.1 EPS32862.1 - 0.082 12.9 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Periplasmic binding protein-like domain Mpv17_PMP22 PF04117.7 EPS32864.1 - 3.7e-14 52.1 0.4 6.2e-12 44.9 0.2 2.3 2 0 0 2 2 2 2 Mpv17 / PMP22 family Cullin_binding PF03556.10 EPS32865.1 - 2.2e-31 108.3 0.4 4.1e-31 107.5 0.3 1.4 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.1 EPS32865.1 - 4.7e-14 51.6 0.8 1.5e-13 49.9 0.6 1.9 2 0 0 2 2 2 1 UBA-like domain CRAL_TRIO_N PF03765.10 EPS32865.1 - 0.085 12.9 0.3 0.27 11.3 0.1 1.9 2 0 0 2 2 2 0 CRAL/TRIO, N-terminal domain UPF0113 PF03657.8 EPS32866.1 - 1.4e-09 37.7 0.0 2.5e-09 36.9 0.0 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0113) PUA PF01472.15 EPS32866.1 - 0.0095 15.6 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 PUA domain NOC3p PF07540.6 EPS32867.1 - 1.6e-34 118.0 0.1 7.8e-34 115.8 0.1 2.3 1 0 0 1 1 1 1 Nucleolar complex-associated protein CBF PF03914.12 EPS32867.1 - 1.4e-31 109.2 0.5 1.4e-31 109.2 0.3 2.5 4 0 0 4 4 4 1 CBF/Mak21 family IFP_35_N PF07334.8 EPS32868.1 - 0.018 15.0 0.3 0.018 15.0 0.2 2.6 3 0 0 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Spc7 PF08317.6 EPS32868.1 - 0.16 10.6 9.6 0.14 10.7 5.2 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF342 PF03961.8 EPS32868.1 - 1.3 7.3 3.8 1.9 6.8 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Strep_SA_rep PF06696.6 EPS32868.1 - 2 8.2 3.8 2.5 7.9 0.5 2.3 2 0 0 2 2 2 0 Streptococcal surface antigen repeat ATP-synt_C PF00137.16 EPS32875.1 - 1.4e-14 53.7 10.1 2.4e-14 52.9 7.0 1.4 1 0 0 1 1 1 1 ATP synthase subunit C DUF1349 PF07081.6 EPS32877.1 - 3.6e-16 59.0 0.0 5e-12 45.5 0.0 3.2 1 1 1 2 2 2 2 Protein of unknown function (DUF1349) PCNP PF15473.1 EPS32877.1 - 0.12 12.7 0.1 0.23 11.7 0.1 1.4 1 0 0 1 1 1 0 PEST, proteolytic signal-containing nuclear protein family Cript PF10235.4 EPS32879.1 - 2.1e-35 120.9 5.8 2.1e-35 120.9 4.0 1.6 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT zf-ribbon_3 PF13248.1 EPS32879.1 - 0.00068 18.7 10.8 0.061 12.5 1.3 3.3 2 1 1 3 3 3 2 zinc-ribbon domain DZR PF12773.2 EPS32879.1 - 0.00088 19.0 16.0 0.0019 17.9 7.0 2.5 1 1 1 2 2 2 2 Double zinc ribbon zinc_ribbon_2 PF13240.1 EPS32879.1 - 0.038 13.4 14.5 0.26 10.8 2.5 3.4 2 1 1 3 3 3 0 zinc-ribbon domain AAA_29 PF13555.1 EPS32879.1 - 0.56 9.7 2.3 13 5.3 1.4 2.4 2 1 0 2 2 2 0 P-loop containing region of AAA domain Rad50_zn_hook PF04423.9 EPS32879.1 - 0.81 9.2 6.9 0.22 11.0 2.7 1.6 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-HYPF PF07503.7 EPS32879.1 - 0.84 9.1 12.1 1.4 8.4 4.9 2.4 2 0 0 2 2 2 0 HypF finger zf-BED PF02892.10 EPS32879.1 - 1.6 8.5 5.8 13 5.6 0.1 2.5 2 0 0 2 2 2 0 BED zinc finger DUF1272 PF06906.6 EPS32879.1 - 3.8 7.4 14.2 9.5 6.1 6.7 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1272) zf-C3HC4_3 PF13920.1 EPS32879.1 - 4.4 7.0 14.7 29 4.4 0.1 2.8 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF2039 PF10217.4 EPS32879.1 - 4.9 7.2 19.6 1.9 8.5 8.5 2.5 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) zf-RING_5 PF14634.1 EPS32879.1 - 5.5 6.8 14.5 72 3.2 0.0 3.0 2 1 0 2 2 2 0 zinc-RING finger domain MRP-L46 PF11788.3 EPS32880.1 - 1.2e-34 119.2 0.3 2.9e-34 118.0 0.2 1.7 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX_4 PF14815.1 EPS32880.1 - 3.1e-05 23.3 0.4 0.00014 21.2 0.3 2.0 1 1 0 1 1 1 1 NUDIX domain NUDIX PF00293.23 EPS32880.1 - 0.0022 17.6 0.0 0.0038 16.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain CAF1 PF04857.15 EPS32881.1 - 5.1e-45 153.8 0.0 6.8e-45 153.4 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.15 EPS32881.1 - 0.026 13.9 0.1 0.18 11.2 0.0 2.1 2 0 0 2 2 2 0 3'-5' exonuclease Ice_nucleation PF00818.12 EPS32881.1 - 0.11 11.9 0.1 0.19 11.1 0.1 1.4 1 0 0 1 1 1 0 Ice nucleation protein repeat Peptidase_S30 PF01577.11 EPS32882.1 - 0.21 10.9 3.5 0.36 10.1 2.5 1.4 1 0 0 1 1 1 0 Potyvirus P1 protease DUF572 PF04502.8 EPS32882.1 - 2.1 7.4 16.2 0.056 12.6 6.8 1.4 2 0 0 2 2 2 0 Family of unknown function (DUF572) adh_short PF00106.20 EPS32883.1 - 1e-15 58.0 0.0 1.5e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPS32883.1 - 0.0041 16.8 0.0 0.0062 16.2 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF4137 PF13593.1 EPS32884.1 - 2e-86 289.9 21.3 2.2e-86 289.7 14.7 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.11 EPS32884.1 - 1.4e-11 44.1 7.6 1.4e-11 44.1 5.2 2.1 2 1 0 2 2 2 1 Sodium Bile acid symporter family ET PF01684.11 EPS32884.1 - 0.11 12.5 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 ET module Sdh_cyt PF01127.17 EPS32885.1 - 0.01 15.6 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Mito_carr PF00153.22 EPS32886.1 - 1.6e-67 223.2 2.8 1.7e-22 78.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Cofilin_ADF PF00241.15 EPS32887.1 - 1.1e-15 57.6 0.0 1.2e-06 28.4 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein PHF5 PF03660.9 EPS32888.1 - 5.5e-52 174.3 9.9 6.2e-52 174.1 6.8 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 EPS32888.1 - 0.7 9.7 15.5 0.16 11.8 5.3 2.8 1 1 2 3 3 3 0 Double zinc ribbon Prok-RING_1 PF14446.1 EPS32888.1 - 2.6 7.8 17.0 2.9 7.6 0.5 3.1 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 PHD PF00628.24 EPS32888.1 - 6.2 6.5 15.2 36 4.1 9.5 2.5 1 1 1 2 2 2 0 PHD-finger Pinin_SDK_memA PF04696.8 EPS32889.1 - 1.4e-29 102.3 9.2 2.3e-29 101.6 6.4 1.3 1 0 0 1 1 1 1 pinin/SDK/memA/ protein conserved region DUF3523 PF12037.3 EPS32889.1 - 0.059 12.3 10.1 0.1 11.5 7.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) DUF4337 PF14235.1 EPS32889.1 - 5.4 6.8 6.0 12 5.6 4.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Abhydrolase_6 PF12697.2 EPS32890.1 - 6.2e-32 111.3 0.1 8.5e-32 110.8 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPS32890.1 - 3.6e-19 69.2 0.0 4.8e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPS32890.1 - 2.1e-11 43.7 0.0 1.3e-10 41.2 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EPS32890.1 - 0.003 17.3 0.0 0.0061 16.3 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_4 PF08386.5 EPS32890.1 - 0.038 13.8 0.0 0.081 12.8 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Saccharop_dh PF03435.13 EPS32891.1 - 3.2e-22 79.0 0.0 5.2e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Ribosomal_L37ae PF01780.14 EPS32892.1 - 5.5e-40 135.1 10.0 6e-40 135.0 6.9 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family A2L_zn_ribbon PF08792.5 EPS32892.1 - 0.0055 16.1 3.4 1 8.8 0.1 2.2 2 0 0 2 2 2 2 A2L zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 EPS32892.1 - 0.0066 16.2 2.4 0.01 15.6 1.7 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain GCC2_GCC3 PF07699.8 EPS32892.1 - 0.033 13.7 0.5 0.051 13.1 0.4 1.3 1 0 0 1 1 1 0 GCC2 and GCC3 NOB1_Zn_bind PF08772.6 EPS32892.1 - 0.092 12.5 2.9 0.31 10.8 0.2 2.3 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-C2H2_4 PF13894.1 EPS32892.1 - 0.14 12.5 0.5 11 6.6 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.10 EPS32892.1 - 0.17 11.6 5.2 1.1 9.0 0.3 2.4 1 1 1 2 2 2 0 BED zinc finger Tnp_zf-ribbon_2 PF13842.1 EPS32892.1 - 0.36 11.2 3.0 0.8 10.1 2.1 1.7 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon zf-C2H2 PF00096.21 EPS32892.1 - 0.71 10.3 2.9 17 6.0 0.3 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type CarbpepA_inh PF02977.10 EPS32892.1 - 1.3 8.6 5.2 1 8.9 0.4 2.2 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor zf-H2C2_2 PF13465.1 EPS32892.1 - 2 8.8 4.2 17 5.9 0.2 2.3 1 1 1 2 2 2 0 Zinc-finger double domain PHD PF00628.24 EPS32893.1 - 3.3e-09 36.3 14.7 5.9e-09 35.4 5.5 2.5 2 0 0 2 2 2 1 PHD-finger zf-RING_2 PF13639.1 EPS32893.1 - 3.3e-09 36.4 0.6 3.3e-09 36.4 0.4 3.3 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.1 EPS32893.1 - 2.5e-06 27.0 0.5 2.5e-06 27.0 0.3 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPS32893.1 - 6.9e-06 25.6 0.1 6.9e-06 25.6 0.1 2.9 4 0 0 4 4 4 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EPS32893.1 - 1.1e-05 25.3 0.8 1.1e-05 25.3 0.5 3.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EPS32893.1 - 1.1e-05 25.4 1.8 1.1e-05 25.4 1.3 2.3 2 1 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EPS32893.1 - 3.4e-05 23.4 1.3 3.4e-05 23.4 0.9 2.5 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.1 EPS32893.1 - 0.00032 19.9 1.7 0.00032 19.9 1.2 1.9 2 0 0 2 2 2 1 PHD-finger Prok-RING_4 PF14447.1 EPS32893.1 - 0.0016 17.9 4.9 0.0026 17.2 0.2 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 EPS32893.1 - 0.0058 16.4 0.1 0.0058 16.4 0.0 1.8 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Astacin PF01400.19 EPS32893.1 - 0.012 15.0 0.2 0.17 11.2 0.1 2.0 1 1 0 1 1 1 0 Astacin (Peptidase family M12A) zf-C2HC_2 PF13913.1 EPS32893.1 - 0.2 11.3 3.7 0.99 9.1 0.2 2.6 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Abhydrolase_3 PF07859.8 EPS32895.1 - 3.5e-44 150.9 0.0 4.6e-44 150.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EPS32895.1 - 2.6e-08 33.0 1.1 8.1e-08 31.4 0.8 1.6 1 1 0 1 1 1 1 Carboxylesterase family DLH PF01738.13 EPS32895.1 - 0.0087 15.3 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 EPS32895.1 - 0.051 12.8 0.0 2.8 7.0 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family GMC_oxred_N PF00732.14 EPS32896.1 - 2.2e-58 197.7 0.0 3.1e-58 197.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EPS32896.1 - 9.7e-33 113.4 0.0 1.7e-32 112.7 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EPS32896.1 - 0.00016 21.6 0.0 0.00039 20.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EPS32896.1 - 0.0029 16.5 0.1 0.025 13.4 0.0 2.3 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPS32896.1 - 0.0049 15.7 1.3 0.1 11.4 0.8 2.2 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 EPS32896.1 - 0.058 12.3 0.1 0.12 11.2 0.1 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EPS32896.1 - 0.064 13.1 0.0 0.68 9.7 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase EnY2 PF10163.4 EPS32897.1 - 0.0037 17.1 0.0 0.0063 16.4 0.0 1.3 1 0 0 1 1 1 1 Transcription factor e(y)2 RA PF00788.18 EPS32898.1 - 8.1e-16 58.2 0.0 1.5e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SAM_2 PF07647.12 EPS32898.1 - 1.2e-15 57.1 0.0 2.1e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EPS32898.1 - 1.4e-13 50.7 0.0 2.5e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Angiomotin_C PF12240.3 EPS32898.1 - 0.021 14.3 0.3 0.038 13.5 0.2 1.4 1 0 0 1 1 1 0 Angiomotin C terminal TMF_TATA_bd PF12325.3 EPS32898.1 - 0.033 13.9 0.8 0.058 13.1 0.6 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF2730 PF10805.3 EPS32898.1 - 0.12 12.0 0.2 0.22 11.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) GNT-I PF03071.10 EPS32898.1 - 0.16 10.4 0.1 0.23 9.9 0.1 1.1 1 0 0 1 1 1 0 GNT-I family Polysacc_deac_1 PF01522.16 EPS32900.1 - 4.1e-28 97.5 0.0 7.4e-28 96.6 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 EPS32900.1 - 0.00077 19.3 16.4 0.00077 19.3 11.4 2.7 2 1 0 2 2 2 1 Chitin recognition protein HrcA_DNA-bdg PF03444.10 EPS32900.1 - 0.17 11.3 0.0 0.34 10.3 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding HEAT_2 PF13646.1 EPS32901.1 - 1.5e-06 28.3 0.1 0.00016 21.9 0.0 2.8 2 2 0 2 2 2 1 HEAT repeats HEAT PF02985.17 EPS32901.1 - 1.4e-05 24.7 0.4 0.023 14.7 0.0 4.7 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 EPS32901.1 - 9.7e-05 22.7 4.0 0.95 10.0 0.0 4.8 3 2 3 6 6 6 3 HEAT-like repeat Adaptin_N PF01602.15 EPS32901.1 - 0.0022 16.4 0.3 0.16 10.2 0.0 2.8 2 1 1 3 3 3 1 Adaptin N terminal region Cnd3 PF12719.2 EPS32901.1 - 0.01 14.8 0.1 0.023 13.6 0.0 1.5 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain UME PF08064.8 EPS32901.1 - 0.018 14.9 0.0 6.4 6.7 0.0 3.0 2 1 0 2 2 2 0 UME (NUC010) domain Cnd1 PF12717.2 EPS32901.1 - 0.02 14.7 0.0 0.19 11.5 0.0 2.5 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 EPS32901.1 - 0.025 14.9 0.0 0.15 12.5 0.0 2.2 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region DRIM PF07539.7 EPS32901.1 - 0.026 13.9 0.1 0.11 11.8 0.0 2.1 2 1 0 2 2 2 0 Down-regulated in metastasis Tetraspannin PF00335.15 EPS32903.1 - 0.061 12.5 0.0 0.084 12.1 0.0 1.2 1 0 0 1 1 1 0 Tetraspanin family Glyoxalase_3 PF13468.1 EPS32906.1 - 2.1e-23 83.1 0.1 2.6e-23 82.8 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain TRAM_LAG1_CLN8 PF03798.11 EPS32909.1 - 3e-36 124.8 18.0 3e-36 124.8 12.5 1.7 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EPS32909.1 - 4.7e-23 80.4 0.1 1.3e-22 79.0 0.0 1.8 2 0 0 2 2 2 1 TRAM1-like protein Sugar_tr PF00083.19 EPS32910.1 - 2.5e-107 359.2 22.5 2.9e-107 359.0 15.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS32910.1 - 3.9e-25 88.3 23.5 3.9e-25 88.3 16.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EPS32910.1 - 7e-06 24.6 9.9 0.00035 19.0 0.3 3.3 4 0 0 4 4 4 2 MFS/sugar transport protein Transglut_core PF01841.14 EPS32912.1 - 3.2e-13 49.8 0.0 5.6e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily DUF553 PF04473.7 EPS32912.1 - 0.088 12.0 0.0 0.94 8.7 0.0 2.4 2 1 0 2 2 2 0 Transglutaminase-like domain Ras PF00071.17 EPS32914.1 - 3.2e-31 107.8 0.2 4.2e-31 107.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPS32914.1 - 2.3e-20 73.2 0.1 9.5e-20 71.2 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EPS32914.1 - 1.1e-06 28.0 0.1 1.4e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EPS32914.1 - 3.9e-05 22.8 0.2 5.4e-05 22.4 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.6 EPS32914.1 - 0.024 13.3 0.3 0.5 8.9 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) G-alpha PF00503.15 EPS32914.1 - 0.044 12.4 6.2 0.23 10.1 0.0 2.5 2 1 1 3 3 3 0 G-protein alpha subunit WD40 PF00400.27 EPS32916.1 - 2.6e-27 93.6 4.0 1.1e-09 37.7 0.0 4.7 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EPS32916.1 - 8e-21 73.7 0.0 2e-20 72.4 0.0 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Nup160 PF11715.3 EPS32916.1 - 0.0022 16.2 1.1 0.003 15.7 0.2 1.5 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Apc4_WD40 PF12894.2 EPS32916.1 - 0.019 14.4 0.0 1.2 8.6 0.0 3.5 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain PAAR_motif PF05488.8 EPS32919.1 - 0.062 13.3 0.4 0.12 12.3 0.0 1.6 2 0 0 2 2 2 0 PAAR motif Fungal_trans PF04082.13 EPS32920.1 - 6.7e-24 84.1 2.0 1.2e-23 83.3 1.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EPS32920.1 - 6.1e-10 38.8 12.7 0.00015 21.8 2.7 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EPS32920.1 - 1.2e-06 28.4 5.9 1.2e-06 28.4 4.1 3.3 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EPS32920.1 - 0.00028 21.0 17.5 0.023 15.0 2.4 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EPS32920.1 - 0.15 12.2 3.2 0.19 11.9 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EPS32920.1 - 4 7.4 6.7 2.6 8.0 0.7 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Clathrin PF00637.15 EPS32922.1 - 1.2e-22 79.9 0.5 1e-20 73.8 0.3 2.5 2 0 0 2 2 2 1 Region in Clathrin and VPS VPS11_C PF12451.3 EPS32922.1 - 2.4e-19 68.9 0.1 5.4e-19 67.7 0.1 1.7 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal TPR_14 PF13428.1 EPS32922.1 - 7.5e-05 23.0 0.2 0.063 13.9 0.0 3.4 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-RING_5 PF14634.1 EPS32922.1 - 0.0019 17.8 5.8 0.0038 16.9 4.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain TPR_11 PF13414.1 EPS32922.1 - 0.0027 17.2 0.9 0.0074 15.9 0.1 2.1 2 0 0 2 2 2 1 TPR repeat zf-C3HC4_2 PF13923.1 EPS32922.1 - 0.0035 17.3 5.5 0.0065 16.4 3.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPS32922.1 - 0.0046 16.7 6.9 0.0087 15.8 4.8 1.5 1 0 0 1 1 1 1 Ring finger domain TPR_12 PF13424.1 EPS32922.1 - 0.0079 16.1 5.0 0.018 14.9 0.3 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat zf-rbx1 PF12678.2 EPS32922.1 - 0.012 15.6 1.9 0.023 14.7 1.3 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger DUF2334 PF10096.4 EPS32922.1 - 0.021 14.2 0.1 0.043 13.2 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) TPR_2 PF07719.12 EPS32922.1 - 0.028 14.3 2.2 0.066 13.1 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-C3HC4 PF00097.20 EPS32922.1 - 0.03 13.9 5.0 0.056 13.1 3.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_16 PF13432.1 EPS32922.1 - 0.039 14.6 0.7 0.12 13.0 0.2 2.1 2 0 0 2 2 1 0 Tetratricopeptide repeat zf-C3HC4_3 PF13920.1 EPS32922.1 - 0.08 12.6 4.9 0.16 11.6 3.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_8 PF13181.1 EPS32922.1 - 0.1 12.4 3.1 0.11 12.2 0.1 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 EPS32922.1 - 0.21 11.9 2.1 2.4 8.5 0.2 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-RING_6 PF14835.1 EPS32922.1 - 0.23 11.2 1.7 0.53 10.1 1.1 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Nha1_C PF08619.5 EPS32923.1 - 9.7e-99 331.5 45.7 1.6e-98 330.8 31.6 1.4 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.16 EPS32923.1 - 3.2e-67 226.7 12.4 4.1e-67 226.3 8.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF21 PF01595.15 EPS32923.1 - 1.3 8.3 8.3 0.14 11.4 1.8 2.2 3 0 0 3 3 3 0 Domain of unknown function DUF21 PX PF00787.19 EPS32924.1 - 2.5e-17 62.6 0.2 4.7e-17 61.7 0.1 1.4 1 0 0 1 1 1 1 PX domain Tmemb_cc2 PF10267.4 EPS32924.1 - 0.01 14.4 0.3 0.014 13.9 0.2 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Pro_dh PF01619.13 EPS32925.1 - 3.4e-35 121.5 0.0 5e-35 120.9 0.0 1.2 1 0 0 1 1 1 1 Proline dehydrogenase Fungal_trans PF04082.13 EPS32926.1 - 4.3e-13 48.7 0.1 8.4e-13 47.7 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS32926.1 - 2.3e-08 33.7 9.0 4.4e-08 32.8 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATG2_CAD PF13329.1 EPS32926.1 - 0.02 14.4 2.1 0.036 13.6 1.4 1.3 1 0 0 1 1 1 0 Autophagy-related protein 2 CAD motif AAA PF00004.24 EPS32927.1 - 1.4e-05 25.3 0.2 9.5e-05 22.6 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EPS32927.1 - 0.0012 19.6 0.0 0.0033 18.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EPS32927.1 - 0.0014 17.4 0.4 0.009 14.7 0.0 2.2 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 EPS32927.1 - 0.0026 17.7 0.0 0.0064 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EPS32927.1 - 0.0059 16.7 0.0 0.019 15.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EPS32927.1 - 0.039 12.8 0.0 0.07 12.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Phage-tail_1 PF09097.5 EPS32928.1 - 0.055 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Baseplate structural protein, domain 1 DUF1785 PF08699.5 EPS32929.1 - 0.012 14.9 0.0 0.031 13.6 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1785) Cofilin_ADF PF00241.15 EPS32929.1 - 0.033 14.0 0.0 0.035 14.0 0.0 1.1 1 0 0 1 1 1 0 Cofilin/tropomyosin-type actin-binding protein BSD PF03909.12 EPS32929.1 - 0.059 13.1 0.0 0.092 12.4 0.0 1.3 1 0 0 1 1 1 0 BSD domain LRR_4 PF12799.2 EPS32930.1 - 3.5e-27 93.5 41.4 2.1e-07 30.4 1.4 8.5 3 2 8 11 11 11 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPS32930.1 - 9.2e-27 92.5 37.2 1.8e-08 34.0 2.5 6.7 4 1 2 7 7 7 6 Leucine rich repeat LRR_6 PF13516.1 EPS32930.1 - 1.6e-11 43.0 28.8 0.22 11.7 0.0 10.1 7 1 2 9 9 9 5 Leucine Rich repeat LRR_1 PF00560.28 EPS32930.1 - 3.6e-10 38.4 34.3 0.14 12.3 0.2 11.9 10 2 0 10 10 10 4 Leucine Rich Repeat LRR_7 PF13504.1 EPS32930.1 - 3.2e-08 32.4 43.8 0.86 10.0 0.1 12.1 13 0 0 13 13 13 6 Leucine rich repeat LRR_9 PF14580.1 EPS32930.1 - 3.6e-07 29.9 11.9 0.12 11.9 0.1 4.3 1 1 3 4 4 4 3 Leucine-rich repeat MFS_1 PF07690.11 EPS32931.1 - 6.3e-31 107.3 33.0 3.9e-25 88.3 8.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily NfeD PF01957.13 EPS32931.1 - 0.74 9.9 0.0 0.74 9.9 0.0 3.5 3 1 1 5 5 5 0 NfeD-like C-terminal, partner-binding DAO PF01266.19 EPS32932.1 - 3.1e-50 171.0 0.0 3.9e-50 170.7 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPS32932.1 - 4.2e-05 23.4 0.5 0.00034 20.5 0.3 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EPS32932.1 - 0.0019 18.3 0.0 0.15 12.0 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EPS32932.1 - 0.035 13.1 0.1 0.054 12.5 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.19 EPS32932.1 - 0.25 10.1 2.1 4.2 6.0 1.3 2.0 2 0 0 2 2 2 0 FAD binding domain LysM PF01476.15 EPS32933.1 - 1.3e-16 60.2 0.0 1e-05 25.3 0.0 3.3 3 0 0 3 3 3 3 LysM domain Methyltransf_31 PF13847.1 EPS32934.1 - 3.8e-26 91.4 0.0 4.6e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPS32934.1 - 5.1e-24 84.5 0.1 8.1e-24 83.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS32934.1 - 1.6e-16 60.8 0.0 2.9e-16 60.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPS32934.1 - 1.9e-16 60.3 0.1 3.1e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPS32934.1 - 2.2e-16 59.6 0.0 3.2e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EPS32934.1 - 2.4e-15 56.7 0.1 4e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPS32934.1 - 3.4e-15 56.1 0.0 5.3e-15 55.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPS32934.1 - 3.8e-10 39.3 0.0 5.4e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EPS32934.1 - 4.8e-10 39.5 0.0 8.3e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EPS32934.1 - 4.2e-09 36.2 0.0 5.8e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 EPS32934.1 - 5.2e-09 35.7 0.0 7.8e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.12 EPS32934.1 - 9.2e-08 31.3 0.0 1.9e-07 30.3 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_9 PF08003.6 EPS32934.1 - 8.7e-07 27.9 0.2 7.3e-06 24.8 0.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.15 EPS32934.1 - 0.00022 20.4 0.0 0.00037 19.6 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.6 EPS32934.1 - 0.00023 20.6 0.0 0.00036 19.9 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) UPF0020 PF01170.13 EPS32934.1 - 0.00029 20.4 0.0 0.00052 19.6 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.8 EPS32934.1 - 0.00089 18.4 0.0 0.0012 18.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.15 EPS32934.1 - 0.0013 17.8 0.0 0.002 17.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DREV PF05219.7 EPS32934.1 - 0.0025 16.7 0.0 0.0039 16.0 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase GidB PF02527.10 EPS32934.1 - 0.012 14.7 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G TehB PF03848.9 EPS32934.1 - 0.014 14.5 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_32 PF13679.1 EPS32934.1 - 0.058 13.0 0.0 0.093 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Sulfatase PF00884.18 EPS32935.1 - 2.5e-18 66.3 0.5 8.3e-18 64.6 0.1 1.9 2 0 0 2 2 2 1 Sulfatase Phosphodiest PF01663.17 EPS32935.1 - 4.4e-06 26.2 0.1 6.7e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EPS32935.1 - 0.021 13.2 0.0 0.028 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Glyco_hydro_62 PF03664.8 EPS32936.1 - 7.5e-144 477.8 10.7 8.6e-144 477.6 7.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 TIP120 PF08623.5 EPS32937.1 - 3.7e-61 205.6 0.1 1.7e-60 203.4 0.0 2.2 2 0 0 2 2 2 1 TATA-binding protein interacting (TIP20) HEAT PF02985.17 EPS32937.1 - 4.1e-06 26.4 12.6 0.28 11.3 0.0 8.2 9 0 0 9 9 9 2 HEAT repeat Rpr2 PF04032.11 EPS32937.1 - 0.00015 21.5 0.5 0.00041 20.1 0.3 1.8 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Adaptin_N PF01602.15 EPS32937.1 - 0.00024 19.5 0.3 0.36 9.0 0.0 3.6 3 1 0 3 3 3 1 Adaptin N terminal region HEAT_EZ PF13513.1 EPS32937.1 - 0.0028 18.1 17.6 0.91 10.0 0.0 7.3 6 1 2 8 8 8 2 HEAT-like repeat FYVE PF01363.16 EPS32937.1 - 0.009 15.8 5.1 0.021 14.7 3.5 1.5 1 0 0 1 1 1 1 FYVE zinc finger Pox_E8 PF03394.8 EPS32937.1 - 0.17 11.1 0.0 0.41 9.9 0.0 1.5 1 0 0 1 1 1 0 Poxvirus E8 protein DUF320 PF03777.8 EPS32937.1 - 8.8 6.1 8.2 0.22 11.3 0.9 2.0 2 0 0 2 2 2 0 Small secreted domain (DUF320) DBR1 PF05011.8 EPS32938.1 - 1.2e-36 125.7 0.1 3.3e-36 124.3 0.0 1.8 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 EPS32938.1 - 3.3e-09 36.4 0.5 5.4e-09 35.7 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2435 PF10363.4 EPS32939.1 - 1e-26 92.6 0.6 1.4e-25 89.0 0.1 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 EPS32939.1 - 4.3e-10 38.8 0.0 1.6e-09 37.0 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) HEAT_EZ PF13513.1 EPS32939.1 - 2.1 8.9 10.1 3.2 8.3 0.0 5.7 7 0 0 7 7 7 0 HEAT-like repeat zf-ZPR1 PF03367.8 EPS32941.1 - 3.6e-92 305.7 0.0 6.8e-45 152.1 0.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain E7 PF00527.13 EPS32941.1 - 0.36 11.0 2.6 1.5 9.0 0.0 2.8 3 0 0 3 3 3 0 E7 protein, Early protein Pro_isomerase PF00160.16 EPS32942.1 - 2e-37 128.7 0.0 2.5e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ORC6 PF05460.8 EPS32943.1 - 6.4e-88 295.2 0.0 7.6e-88 294.9 0.0 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) DUF2419 PF10343.4 EPS32944.1 - 1.4e-143 477.4 0.0 1.7e-143 477.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) GATase_7 PF13537.1 EPS32944.1 - 0.042 13.5 0.1 0.2 11.3 0.0 2.0 2 0 0 2 2 2 0 Glutamine amidotransferase domain DUF1162 PF06650.7 EPS32944.1 - 0.083 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1162) DUF1563 PF07599.6 EPS32944.1 - 0.1 12.4 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1563) ThiF PF00899.16 EPS32945.1 - 1e-41 141.9 0.0 3.8e-41 140.0 0.0 2.0 2 0 0 2 2 2 1 ThiF family UBACT PF02134.16 EPS32945.1 - 2.5e-28 97.4 0.3 5.2e-28 96.4 0.2 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EPS32945.1 - 5.2e-18 64.1 2.7 9.9e-18 63.2 1.9 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 EPS32945.1 - 7e-16 58.1 1.0 1.8e-15 56.7 0.2 2.0 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.1 EPS32945.1 - 6.3e-05 23.1 0.0 0.00046 20.4 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EPS32945.1 - 0.0025 17.9 0.0 0.0052 16.8 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 EPS32945.1 - 0.045 14.1 0.5 0.32 11.4 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF3192 PF11399.3 EPS32945.1 - 0.066 13.1 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3192) K-box PF01486.12 EPS32945.1 - 0.25 11.1 1.4 0.41 10.4 0.3 1.8 2 0 0 2 2 2 0 K-box region adh_short PF00106.20 EPS32946.1 - 1.2e-27 96.8 0.5 2e-27 96.1 0.3 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPS32946.1 - 2.8e-15 56.7 0.0 3.9e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPS32946.1 - 8.1e-13 48.4 1.0 2.2e-12 47.0 0.7 1.6 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EPS32946.1 - 8.2e-07 28.2 0.0 1.1e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EPS32946.1 - 3.9e-05 22.7 0.6 5.4e-05 22.2 0.4 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EPS32946.1 - 4.2e-05 23.0 0.3 0.00023 20.6 0.2 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 EPS32946.1 - 0.002 18.5 0.1 0.0049 17.2 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EPS32946.1 - 0.02 14.9 0.1 0.088 12.9 0.1 2.0 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Methyltransf_25 PF13649.1 EPS32946.1 - 0.025 14.9 0.0 0.041 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Saccharop_dh PF03435.13 EPS32946.1 - 0.036 13.0 0.0 0.052 12.5 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 EPS32946.1 - 0.055 13.4 1.2 0.16 11.9 0.3 2.1 2 1 0 2 2 2 0 NADH(P)-binding WASH-7_mid PF14744.1 EPS32946.1 - 0.085 11.6 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 WASH complex subunit 7 Vhr1 PF04001.8 EPS32946.1 - 0.11 12.4 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 Transcription factor Vhr1 Skp1_POZ PF03931.10 EPS32947.1 - 6.2e-12 45.4 0.0 8.3e-12 45.0 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain zf-C3HC4_3 PF13920.1 EPS32948.1 - 7.4e-09 35.1 11.6 1.3e-08 34.3 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPS32948.1 - 8.1 6.5 16.3 18 5.4 11.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Malic_M PF03949.10 EPS32949.1 - 5.5e-82 275.1 0.0 7.7e-82 274.6 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EPS32949.1 - 1.3e-65 220.4 0.4 2e-65 219.7 0.0 1.5 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain CFEM PF05730.6 EPS32950.1 - 6.4e-16 57.9 11.8 1.2e-15 57.0 8.2 1.5 1 0 0 1 1 1 1 CFEM domain DNA_pol_delta_4 PF04081.8 EPS32951.1 - 9.4e-27 93.7 0.3 1.3e-26 93.2 0.2 1.2 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 Arrestin_C PF02752.17 EPS32953.1 - 1.7e-13 50.8 0.3 5e-13 49.3 0.0 1.9 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain DHO_dh PF01180.16 EPS32953.1 - 0.069 12.1 0.0 0.099 11.5 0.0 1.2 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase NAAA-beta PF15508.1 EPS32954.1 - 0.074 13.4 0.0 0.086 13.1 0.0 1.2 1 0 0 1 1 1 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase tRNA_int_end_N2 PF12928.2 EPS32955.1 - 3.2e-35 119.4 0.0 5.9e-35 118.5 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 EPS32955.1 - 0.0038 16.7 0.0 0.0077 15.7 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, N-terminal domain Mito_fiss_reg PF05308.6 EPS32955.1 - 0.59 9.4 6.4 0.96 8.7 4.5 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 EPS32955.1 - 2.8 7.1 7.5 4.6 6.4 5.2 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal ThiF PF00899.16 EPS32956.1 - 2.7e-08 33.7 0.0 6.6e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 ThiF family Rib_5-P_isom_A PF06026.9 EPS32957.1 - 8.3e-38 129.4 0.0 1.1e-35 122.4 0.0 2.1 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 EPS32957.1 - 0.0082 15.7 0.1 3.7 7.1 0.1 2.2 2 0 0 2 2 2 2 DeoR C terminal sensor domain WD40 PF00400.27 EPS32958.1 - 6.3e-22 76.5 4.4 1.3e-05 24.9 0.2 5.4 6 0 0 6 6 6 4 WD domain, G-beta repeat SGL PF08450.7 EPS32958.1 - 0.00017 21.0 0.0 0.035 13.4 0.0 2.2 2 0 0 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region ATP_bind_1 PF03029.12 EPS32959.1 - 1.4e-74 250.6 0.0 1.8e-74 250.2 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EPS32959.1 - 2.2e-05 25.2 1.5 0.00014 22.6 0.1 2.6 2 1 0 2 2 2 1 AAA domain CbiA PF01656.18 EPS32959.1 - 0.00041 19.8 0.0 0.00085 18.7 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArgK PF03308.11 EPS32959.1 - 0.00062 18.6 0.0 0.0013 17.5 0.0 1.4 1 0 0 1 1 1 1 ArgK protein AAA_30 PF13604.1 EPS32959.1 - 0.00093 18.8 0.5 0.91 9.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EPS32959.1 - 0.0015 17.9 0.5 0.018 14.4 0.0 2.2 1 1 0 2 2 2 1 AAA-like domain AAA_33 PF13671.1 EPS32959.1 - 0.0051 16.6 0.0 0.013 15.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EPS32959.1 - 0.024 14.5 0.0 0.072 13.0 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase Zeta_toxin PF06414.7 EPS32959.1 - 0.055 12.5 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin RuvB_N PF05496.7 EPS32959.1 - 0.12 11.4 0.0 0.2 10.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_29 PF13555.1 EPS32959.1 - 0.12 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 EPS32959.1 - 0.16 12.1 0.0 0.39 10.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 EPS32959.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA PF00004.24 EPS32959.1 - 0.7 10.1 2.6 1 9.5 0.0 2.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) RNase_P_Rpp14 PF01900.14 EPS32960.1 - 1.6e-37 127.6 0.0 2.2e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family Citrate_synt PF00285.16 EPS32961.1 - 5.1e-18 64.9 0.0 1.8e-15 56.5 0.0 3.0 1 1 1 2 2 2 2 Citrate synthase CoA_binding PF02629.14 EPS32961.1 - 5.4e-18 65.2 0.0 2.4e-17 63.2 0.0 2.2 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EPS32961.1 - 4.2e-15 55.6 0.1 6.9e-15 54.9 0.1 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EPS32961.1 - 9.9e-06 25.2 0.0 7.7e-05 22.3 0.0 2.3 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain ATP-grasp_2 PF08442.5 EPS32963.1 - 9.8e-09 34.8 0.0 1.4e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain F-box-like PF12937.2 EPS32964.1 - 4e-07 29.6 2.0 5.8e-06 25.9 0.1 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EPS32964.1 - 0.00082 18.9 0.3 0.006 16.2 0.0 2.4 2 0 0 2 2 2 1 F-box domain 4HBT_3 PF13622.1 EPS32965.1 - 1.9 8.1 7.9 4.8 6.8 5.4 1.8 1 1 0 1 1 1 0 Thioesterase-like superfamily Asp PF00026.18 EPS32966.1 - 1.4e-74 251.2 8.9 1.7e-74 250.8 6.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EPS32966.1 - 2.5e-06 27.8 1.8 0.00095 19.6 0.3 2.8 2 1 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 EPS32966.1 - 0.00027 20.9 5.7 0.00052 20.0 0.3 3.0 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EPS32966.1 - 0.011 15.3 0.1 0.053 13.0 0.0 2.2 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Glyco_hydro_45 PF02015.11 EPS32967.1 - 6e-25 88.4 17.5 6e-25 88.4 12.1 2.2 1 1 1 2 2 2 1 Glycosyl hydrolase family 45 CBM_1 PF00734.13 EPS32967.1 - 5.7e-13 48.2 14.5 5.7e-13 48.2 10.1 2.9 2 0 0 2 2 2 1 Fungal cellulose binding domain DPBB_1 PF03330.13 EPS32967.1 - 4.7e-08 32.9 0.5 4.7e-08 32.9 0.3 2.5 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Sporozoite_P67 PF05642.6 EPS32967.1 - 2.6 5.7 14.7 3 5.5 10.2 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Glyco_hydro_7 PF00840.15 EPS32968.1 - 3.9e-125 417.6 19.6 3.9e-125 417.6 13.6 2.6 2 1 0 2 2 2 1 Glycosyl hydrolase family 7 CBM_1 PF00734.13 EPS32968.1 - 3e-13 49.1 14.6 3e-13 49.1 10.1 3.2 2 0 0 2 2 2 1 Fungal cellulose binding domain Asp PF00026.18 EPS32969.1 - 8.8e-70 235.4 0.0 1.1e-69 235.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EPS32969.1 - 2.9e-07 30.5 0.0 2.4e-06 27.5 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EPS32969.1 - 1.2e-05 25.7 0.4 0.00026 21.4 0.3 2.8 1 1 0 1 1 1 1 Aspartyl protease TAXi_C PF14541.1 EPS32969.1 - 0.026 14.0 0.0 0.22 11.0 0.0 2.1 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal DUF1485 PF07364.7 EPS32970.1 - 2e-72 243.8 2.3 3.3e-72 243.1 1.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1485) MlrC_C PF07171.7 EPS32970.1 - 2.3e-38 131.5 0.1 4.6e-38 130.5 0.1 1.5 1 0 0 1 1 1 1 MlrC C-terminus APH PF01636.18 EPS32971.1 - 0.00023 21.0 0.1 0.00023 21.0 0.0 3.4 3 2 1 4 4 4 1 Phosphotransferase enzyme family Pkinase PF00069.20 EPS32971.1 - 0.0024 17.0 0.0 0.0044 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS32971.1 - 0.018 14.1 0.0 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase RIO1 PF01163.17 EPS32971.1 - 0.087 12.1 0.0 0.087 12.1 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Mnd1 PF03962.10 EPS32971.1 - 8 6.0 8.4 14 5.2 5.8 1.4 1 0 0 1 1 1 0 Mnd1 family HR1 PF02185.11 EPS32971.1 - 8 6.2 10.8 13 5.6 4.9 2.4 1 1 1 2 2 2 0 Hr1 repeat Peptidase_A4 PF01828.12 EPS32972.1 - 2.3e-90 301.2 10.2 2.7e-90 300.9 7.0 1.0 1 0 0 1 1 1 1 Peptidase A4 family NAD_binding_8 PF13450.1 EPS32973.1 - 3.9e-11 42.8 0.0 1.1e-10 41.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EPS32973.1 - 6.7e-06 25.4 0.0 1.1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 EPS32973.1 - 6.9e-06 25.1 0.1 9.9e-06 24.6 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EPS32973.1 - 1.1e-05 24.4 0.0 2.4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EPS32973.1 - 2.9e-05 22.7 0.0 9.1e-05 21.0 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 EPS32973.1 - 0.00011 21.4 0.1 0.0002 20.5 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EPS32973.1 - 0.00036 20.4 0.0 0.00054 19.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPS32973.1 - 0.00044 20.3 0.0 0.00096 19.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPS32973.1 - 0.0021 17.1 0.1 0.0036 16.4 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EPS32973.1 - 0.0026 16.7 0.0 0.0043 16.0 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EPS32973.1 - 0.0063 16.3 0.3 0.023 14.4 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EPS32973.1 - 0.0077 16.6 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EPS32973.1 - 0.011 14.4 0.3 0.028 13.0 0.1 1.7 2 0 0 2 2 2 0 Tryptophan halogenase GMC_oxred_N PF00732.14 EPS32973.1 - 0.014 14.6 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 GMC oxidoreductase ApbA PF02558.11 EPS32973.1 - 0.024 14.0 0.1 0.047 13.1 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 EPS32973.1 - 0.11 12.5 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain DUSP PF06337.7 EPS32974.1 - 0.068 13.5 0.0 0.093 13.1 0.0 1.2 1 0 0 1 1 1 0 DUSP domain Peptidase_M35 PF02102.10 EPS32975.1 - 1e-181 603.4 20.4 1.2e-181 603.1 14.2 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EPS32975.1 - 4.9e-07 30.3 1.8 1.5e-06 28.7 1.3 1.8 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase GST_C PF00043.20 EPS32975.1 - 0.12 12.3 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF1117 PF06547.7 EPS32975.1 - 0.37 10.9 5.0 0.73 9.9 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1117) Methyltransf_31 PF13847.1 EPS32976.1 - 5.6e-05 22.7 0.0 7e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS32976.1 - 0.0067 17.0 0.0 0.0099 16.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain N36 PF11438.3 EPS32976.1 - 0.096 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 36-mer N-terminal peptide of the N protein (N36) Glyco_hydro_28 PF00295.12 EPS32977.1 - 1.5e-111 372.4 19.0 1.8e-111 372.2 13.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Inhibitor_I42 PF09394.5 EPS32977.1 - 0.089 13.1 0.8 0.2 11.9 0.1 2.0 2 0 0 2 2 2 0 Chagasin family peptidase inhibitor I42 DUF3446 PF11928.3 EPS32977.1 - 4.5 7.5 8.4 15 5.8 1.6 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3446) NAD_binding_8 PF13450.1 EPS32978.1 - 6.3e-13 48.5 1.1 2.9e-12 46.4 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EPS32978.1 - 1.3e-07 31.7 0.0 0.00013 21.8 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EPS32978.1 - 1.1e-06 27.8 0.0 0.00029 19.8 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EPS32978.1 - 7.7e-06 25.7 0.0 5.6e-05 22.9 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EPS32978.1 - 9.2e-06 25.8 0.0 0.00026 21.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPS32978.1 - 2e-05 24.8 0.0 0.2 12.0 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EPS32978.1 - 3.6e-05 22.4 0.1 0.00087 17.8 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 EPS32978.1 - 0.0001 21.3 0.1 0.00015 20.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EPS32978.1 - 0.0025 16.8 0.0 0.0041 16.0 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.18 EPS32978.1 - 0.017 14.8 0.0 0.057 13.1 0.0 1.8 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.12 EPS32978.1 - 0.025 13.6 0.0 0.05 12.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.13 EPS32978.1 - 0.032 13.8 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Amino_oxidase PF01593.19 EPS32978.1 - 0.035 13.2 0.3 3.7 6.5 0.0 3.0 4 0 0 4 4 4 0 Flavin containing amine oxidoreductase Ldh_1_N PF00056.18 EPS32978.1 - 0.047 13.5 0.0 0.079 12.7 0.0 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 EPS32978.1 - 0.057 13.7 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EPS32978.1 - 0.14 11.5 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GIDA PF01134.17 EPS32978.1 - 0.24 10.2 0.1 0.34 9.7 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A MFS_1 PF07690.11 EPS32979.1 - 1.5e-29 102.8 38.6 3.4e-29 101.6 25.3 1.9 2 0 0 2 2 2 2 Major Facilitator Superfamily Peptidase_M20 PF01546.23 EPS32980.1 - 1.5e-05 24.6 0.2 2.4e-05 23.9 0.1 1.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EPS32980.1 - 7.6e-05 22.4 0.0 0.00099 18.8 0.0 2.4 2 1 0 2 2 2 1 Peptidase dimerisation domain Macscav_rec PF03523.8 EPS32980.1 - 0.15 11.8 0.0 27 4.6 0.0 2.6 2 0 0 2 2 2 0 Macrophage scavenger receptor Fungal_trans_2 PF11951.3 EPS32981.1 - 3.5e-19 68.6 0.7 6.9e-09 34.7 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS32981.1 - 3.7e-09 36.3 8.2 7.8e-09 35.3 5.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2919 PF11143.3 EPS32981.1 - 0.0058 16.4 0.0 0.02 14.7 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2919) DUF3237 PF11578.3 EPS32982.1 - 8.8e-49 164.6 0.0 9.8e-49 164.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) Formyl_trans_N PF00551.14 EPS32983.1 - 1.6e-38 132.0 0.1 2.1e-38 131.6 0.1 1.2 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.20 EPS32983.1 - 1.2e-08 34.2 0.0 3.3e-08 32.8 0.0 1.8 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 EPS32983.1 - 8.5e-08 31.8 0.0 2.6e-07 30.2 0.0 1.9 2 0 0 2 2 2 1 ACT domain Glyco_hydro_7 PF00840.15 EPS32984.1 - 6.2e-219 726.7 20.2 9.6e-219 726.0 14.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 CBM_1 PF00734.13 EPS32984.1 - 8.7e-14 50.8 11.3 8.7e-14 50.8 7.8 4.5 6 0 0 6 6 6 1 Fungal cellulose binding domain Dioxygenase_C PF00775.16 EPS32985.1 - 7.1e-43 145.9 0.0 9.4e-43 145.5 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EPS32985.1 - 3.6e-11 42.8 0.0 6.3e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EPS32985.1 - 0.019 15.0 0.0 0.075 13.1 0.0 2.0 2 1 0 2 2 2 0 Carboxypeptidase regulatory-like domain Lactonase PF10282.4 EPS32986.1 - 1.3e-22 80.3 0.0 1.6e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Abhydrolase_6 PF12697.2 EPS32988.1 - 7e-30 104.5 1.7 2.3e-29 102.8 0.2 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPS32988.1 - 2.3e-12 46.9 0.0 3.7e-11 43.0 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPS32988.1 - 1.2e-11 44.5 0.0 1.2e-10 41.3 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EPS32988.1 - 7.6e-06 24.6 0.0 1.2e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.5 EPS32988.1 - 0.0015 18.3 0.0 0.15 11.9 0.0 3.2 4 0 0 4 4 4 1 TAP-like protein Esterase PF00756.15 EPS32988.1 - 0.0094 15.3 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Metallophos PF00149.23 EPS32989.1 - 1.3e-36 125.8 0.1 6.4e-32 110.5 0.0 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase NmrA PF05368.8 EPS32990.1 - 3.7e-27 95.0 0.0 6.1e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPS32990.1 - 2.9e-19 69.7 0.3 6.2e-19 68.7 0.1 1.7 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EPS32990.1 - 4.1e-06 26.3 0.2 2.8e-05 23.6 0.0 2.3 3 1 1 4 4 4 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EPS32990.1 - 6e-05 22.1 0.9 0.00021 20.4 0.1 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 EPS32990.1 - 0.0018 17.0 0.0 0.0034 16.1 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 3HCDH_N PF02737.13 EPS32990.1 - 0.0055 16.3 0.1 0.012 15.2 0.1 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EPS32990.1 - 0.01 16.2 0.3 0.029 14.8 0.0 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.20 EPS32990.1 - 0.012 15.4 1.6 0.024 14.5 0.3 2.1 3 0 0 3 3 3 0 short chain dehydrogenase Semialdhyde_dh PF01118.19 EPS32990.1 - 0.018 15.3 0.1 0.053 13.8 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EPS32990.1 - 0.022 14.6 0.3 0.047 13.6 0.0 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus DFP PF04127.10 EPS32990.1 - 0.028 14.0 0.5 0.064 12.8 0.1 1.7 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein NAD_binding_4 PF07993.7 EPS32990.1 - 0.033 13.1 0.0 0.051 12.4 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein NAD_binding_2 PF03446.10 EPS32990.1 - 0.071 12.9 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase KR PF08659.5 EPS32990.1 - 0.087 12.4 0.7 0.18 11.4 0.1 1.8 2 0 0 2 2 2 0 KR domain Polysacc_synt_2 PF02719.10 EPS32990.1 - 0.13 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Radical_SAM PF04055.16 EPS32991.1 - 5.8e-24 85.1 0.1 1.4e-23 83.8 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.7 EPS32991.1 - 5.5e-22 77.6 0.0 1.9e-21 75.9 0.0 2.0 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.20 EPS32991.1 - 1.3e-08 34.9 0.0 6.8e-05 22.8 0.0 2.6 2 0 0 2 2 2 2 Flavodoxin CcmD PF04995.9 EPS32991.1 - 0.48 10.2 6.0 1.6 8.5 4.2 1.9 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Peptidase_M19 PF01244.16 EPS32992.1 - 4.9e-104 347.7 0.0 5.8e-104 347.4 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Amidohydro_2 PF04909.9 EPS32992.1 - 0.021 14.4 0.0 0.05 13.1 0.0 1.7 1 1 0 1 1 1 0 Amidohydrolase SBP_bac_6 PF13343.1 EPS32992.1 - 0.12 11.6 0.0 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Smg4_UPF3 PF03467.10 EPS32993.1 - 5.3e-24 85.1 0.0 1.7e-23 83.5 0.0 1.8 1 1 0 1 1 1 1 Smg-4/UPF3 family RRM_1 PF00076.17 EPS32993.1 - 1.8e-08 33.8 0.6 1.5e-06 27.7 0.1 3.0 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS32993.1 - 1.9e-05 24.5 0.0 0.00016 21.5 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS32993.1 - 0.00015 21.5 0.0 0.00033 20.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fungal_trans PF04082.13 EPS32994.1 - 1.4e-14 53.5 0.1 4.1e-14 52.0 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS32994.1 - 1.6e-05 24.6 9.6 3.1e-05 23.7 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 EPS32995.1 - 2.2e-15 56.5 1.5 3.1e-14 52.7 1.1 2.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EPS32995.1 - 1.7e-08 34.3 0.4 4e-08 33.1 0.3 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EPS32995.1 - 7.8e-08 31.6 5.0 1.2e-06 27.6 2.3 2.5 1 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EPS32995.1 - 3.1e-05 23.0 0.1 4.3e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EPS32995.1 - 3.5e-05 23.7 1.3 6.8e-05 22.8 0.7 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EPS32995.1 - 9.2e-05 21.6 0.2 0.02 14.0 0.0 2.6 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 EPS32995.1 - 0.00011 22.5 0.7 0.00027 21.2 0.5 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EPS32995.1 - 0.00023 20.1 2.9 0.00051 19.0 1.9 1.5 1 1 1 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 EPS32995.1 - 0.0025 16.9 0.2 0.0034 16.5 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EPS32995.1 - 0.0044 15.9 1.7 0.0077 15.1 1.2 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Rossmann-like PF10727.4 EPS32995.1 - 0.0065 16.1 0.2 0.013 15.2 0.1 1.4 1 0 0 1 1 1 1 Rossmann-like domain Trp_halogenase PF04820.9 EPS32995.1 - 0.0088 14.7 2.5 0.6 8.6 1.1 2.9 3 0 0 3 3 3 1 Tryptophan halogenase 3HCDH_N PF02737.13 EPS32995.1 - 0.026 14.1 1.5 0.043 13.4 1.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 EPS32995.1 - 0.03 12.7 1.8 0.042 12.3 1.3 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_Gly3P_dh_N PF01210.18 EPS32995.1 - 0.032 13.9 0.5 0.057 13.1 0.3 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 EPS32995.1 - 0.057 13.2 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_3 PF13738.1 EPS32995.1 - 0.084 12.9 0.5 0.2 11.7 0.4 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EPS32995.1 - 0.15 11.6 0.4 0.27 10.7 0.3 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.11 EPS32995.1 - 0.51 9.7 2.0 2 7.8 0.6 2.2 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Aldedh PF00171.17 EPS32996.1 - 3.9e-187 622.2 0.8 4.4e-187 622.0 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1446 PF07287.6 EPS32998.1 - 4.9e-121 403.5 0.0 5.8e-121 403.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) Mre11_DNA_bind PF04152.9 EPS32999.1 - 1.5e-60 204.0 0.2 2.7e-60 203.2 0.1 1.5 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 EPS32999.1 - 3.5e-25 88.5 1.2 5.1e-25 88.0 0.8 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EPS32999.1 - 4.1e-05 23.4 0.0 9.4e-05 22.2 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 EPS32999.1 - 0.05 12.7 0.0 0.085 11.9 0.0 1.3 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily F-box-like PF12937.2 EPS33000.1 - 4.7e-11 42.2 0.3 1.2e-10 40.9 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EPS33000.1 - 3.1e-09 36.2 0.2 1.5e-08 34.0 0.0 2.0 2 0 0 2 2 2 1 F-box domain Glyco_hydro_72 PF03198.9 EPS33001.1 - 1e-126 422.2 0.5 1.3e-126 421.9 0.4 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 EPS33001.1 - 0.002 17.1 0.0 0.0046 15.9 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.13 EPS33001.1 - 0.071 12.2 0.4 6.4 5.8 0.0 2.3 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) MAS20 PF02064.10 EPS33002.1 - 9.9e-20 70.6 0.3 5.2e-19 68.3 0.2 1.8 1 1 0 1 1 1 1 MAS20 protein import receptor Ribosomal_L28e PF01778.12 EPS33002.1 - 0.061 13.7 0.3 0.099 13.0 0.2 1.4 1 0 0 1 1 1 0 Ribosomal L28e protein family DsrC PF04358.8 EPS33002.1 - 0.12 12.6 0.1 0.86 9.8 0.0 2.0 1 1 1 2 2 2 0 DsrC like protein DUF1049 PF06305.6 EPS33002.1 - 0.17 11.4 2.5 1.2 8.6 1.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1049) Vps51 PF08700.6 EPS33003.1 - 2.3e-18 65.8 3.4 2.3e-18 65.8 2.3 1.8 2 0 0 2 2 2 1 Vps51/Vps67 COG2 PF06148.6 EPS33003.1 - 0.017 14.9 1.8 0.033 14.0 0.2 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ABC_tran PF00005.22 EPS33004.1 - 1.7e-25 89.9 0.0 2.5e-12 47.2 0.0 3.6 4 1 0 4 4 3 2 ABC transporter AAA_21 PF13304.1 EPS33004.1 - 6.6e-13 49.2 4.2 8.9e-05 22.5 0.0 3.2 2 1 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EPS33004.1 - 1.3e-06 28.2 0.0 0.028 14.3 0.0 2.5 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 EPS33004.1 - 0.0039 17.3 0.0 0.99 9.5 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EPS33004.1 - 0.0054 16.2 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 EPS33004.1 - 0.029 13.4 0.0 1.1 8.2 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_16 PF13191.1 EPS33004.1 - 0.033 14.1 2.7 0.32 10.9 0.2 2.6 2 1 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.1 EPS33004.1 - 0.048 13.9 0.6 0.1 12.9 0.4 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EPS33004.1 - 0.069 13.1 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 EPS33004.1 - 0.083 12.1 0.0 2.5 7.2 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF3584 PF12128.3 EPS33004.1 - 0.093 10.0 0.1 0.13 9.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) NACHT PF05729.7 EPS33004.1 - 0.11 12.1 0.4 0.38 10.4 0.0 2.0 2 0 0 2 2 2 0 NACHT domain G-alpha PF00503.15 EPS33004.1 - 0.11 11.1 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit Miro PF08477.8 EPS33004.1 - 0.13 12.8 0.0 0.33 11.4 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein NB-ARC PF00931.17 EPS33004.1 - 0.2 10.4 0.1 9.7 4.9 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AMP-binding PF00501.23 EPS33005.1 - 8.5e-76 255.0 0.0 1.2e-75 254.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPS33005.1 - 7.4e-10 39.6 0.2 1.4e-09 38.7 0.2 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CPSase_L_D2 PF02786.12 EPS33006.1 - 1.3e-113 377.4 0.2 1.2e-83 279.5 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 EPS33006.1 - 7e-46 154.9 0.0 1.7e-45 153.7 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EPS33006.1 - 8.2e-46 155.8 0.0 2.7e-45 154.2 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase class-I OTCace_N PF02729.16 EPS33006.1 - 1.1e-41 141.8 0.0 2.2e-41 140.8 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.14 EPS33006.1 - 6.9e-40 135.6 0.0 1.5e-39 134.5 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 EPS33006.1 - 1.8e-39 134.2 0.0 7.5e-19 67.8 0.0 2.9 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain OTCace PF00185.19 EPS33006.1 - 1.2e-33 116.2 0.0 2.9e-33 114.9 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATP-grasp_4 PF13535.1 EPS33006.1 - 1.6e-33 116.0 0.1 1.3e-21 77.1 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain MGS PF02142.17 EPS33006.1 - 1.3e-20 73.1 0.0 5.8e-20 71.0 0.0 2.3 1 0 0 1 1 1 1 MGS-like domain ATPgrasp_Ter PF15632.1 EPS33006.1 - 2.3e-19 69.3 0.0 3.6e-09 35.8 0.0 4.2 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EPS33006.1 - 4.9e-16 58.7 0.3 1.1e-07 31.4 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EPS33006.1 - 6.9e-14 51.5 0.0 5.6e-07 29.0 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.9 EPS33006.1 - 5e-06 26.4 0.3 0.11 12.3 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 EPS33006.1 - 1.9e-05 24.1 0.1 0.00047 19.6 0.1 2.5 1 1 0 1 1 1 1 Peptidase C26 RimK PF08443.6 EPS33006.1 - 4.7e-05 22.9 0.0 0.0042 16.5 0.0 2.6 2 0 0 2 2 2 1 RimK-like ATP-grasp domain Ish1 PF10281.4 EPS33006.1 - 0.051 13.6 0.0 2.3 8.3 0.0 3.0 3 0 0 3 3 2 0 Putative stress-responsive nuclear envelope protein DJ-1_PfpI PF01965.19 EPS33006.1 - 0.062 12.7 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 DJ-1/PfpI family Synaptobrevin PF00957.16 EPS33009.1 - 9.3e-32 108.4 0.0 1.3e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EPS33009.1 - 2.6e-24 84.5 0.0 4.3e-24 83.8 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF879 PF05947.7 EPS33009.1 - 0.044 12.1 0.0 0.061 11.6 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF879) Ost4 PF10215.4 EPS33011.1 - 6.5e-18 63.9 1.5 9.2e-18 63.4 1.0 1.2 1 0 0 1 1 1 1 Oligosaccaryltransferase Zn_clus PF00172.13 EPS33012.1 - 1e-09 38.1 6.0 1.7e-09 37.4 4.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EPS33012.1 - 2.8e-09 36.2 0.0 4.4e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RabGAP-TBC PF00566.13 EPS33013.1 - 3.2e-42 144.4 0.0 5.2e-41 140.4 0.0 2.2 2 0 0 2 2 2 1 Rab-GTPase-TBC domain ComZ PF10815.3 EPS33013.1 - 0.089 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 ComZ TPR_MLP1_2 PF07926.7 EPS33013.1 - 0.4 10.4 3.1 0.2 11.3 0.1 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein adh_short PF00106.20 EPS33014.1 - 2e-28 99.3 0.8 3e-28 98.8 0.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPS33014.1 - 1.8e-26 93.3 0.4 2.2e-26 93.1 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPS33014.1 - 4.1e-11 42.8 0.6 9.1e-11 41.7 0.4 1.5 1 1 0 1 1 1 1 KR domain DENN PF02141.16 EPS33015.1 - 2.2e-40 138.3 0.1 4.2e-40 137.4 0.0 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 EPS33015.1 - 0.00011 22.0 0.0 0.00034 20.5 0.0 1.9 1 0 0 1 1 1 1 uDENN domain Elongin_A PF06881.6 EPS33015.1 - 0.013 15.8 5.4 0.013 15.8 3.7 2.6 3 1 1 4 4 4 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DivIVA PF05103.8 EPS33015.1 - 3.3 7.7 16.8 1.1 9.3 6.6 3.1 1 1 1 2 2 2 0 DivIVA protein DUF2570 PF10828.3 EPS33015.1 - 5 6.7 10.2 4.7 6.8 5.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) ADIP PF11559.3 EPS33015.1 - 6.1 6.7 19.0 2.8 7.8 3.6 2.6 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Pkinase PF00069.20 EPS33016.1 - 8.9e-25 87.3 0.0 1.3e-24 86.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 EPS33016.1 - 3.7e-13 48.7 8.4 1.4e-09 37.4 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat HEAT PF02985.17 EPS33016.1 - 1.7e-10 40.0 1.5 0.13 12.4 0.1 6.5 6 0 0 6 6 6 2 HEAT repeat Pkinase_Tyr PF07714.12 EPS33016.1 - 4.5e-05 22.6 0.0 7.4e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.1 EPS33016.1 - 8.2e-05 22.8 0.4 0.64 10.3 0.0 4.2 1 1 4 5 5 5 2 HEAT repeats HEAT_EZ PF13513.1 EPS33016.1 - 0.07 13.6 2.1 1.6 9.3 0.2 3.8 4 0 0 4 4 4 0 HEAT-like repeat DUF2435 PF10363.4 EPS33016.1 - 0.11 12.3 1.9 0.91 9.4 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2435) zf-C2H2_4 PF13894.1 EPS33019.1 - 3.9e-08 33.0 19.9 0.0038 17.4 0.0 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EPS33019.1 - 4.5e-07 29.8 30.2 0.001 19.2 0.1 3.8 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EPS33019.1 - 0.00058 20.0 18.2 0.0058 16.8 0.5 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-Di19 PF05605.7 EPS33019.1 - 0.056 13.5 0.6 0.056 13.5 0.4 2.6 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 EPS33019.1 - 0.2 11.8 6.0 4.3 7.6 0.0 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Rpr2 PF04032.11 EPS33019.1 - 0.31 10.9 8.3 2.1 8.2 2.7 2.4 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-C2H2_jaz PF12171.3 EPS33019.1 - 0.32 11.2 0.1 0.32 11.2 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Endonuclease_7 PF02945.10 EPS33019.1 - 0.49 10.1 11.5 0.087 12.5 4.5 2.0 1 1 1 2 2 2 0 Recombination endonuclease VII zf-C2H2_6 PF13912.1 EPS33019.1 - 5.6 7.0 16.5 1.3 8.9 0.8 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger NUDIX PF00293.23 EPS33021.1 - 1.5e-28 99.0 0.0 2.2e-28 98.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DUF202 PF02656.10 EPS33022.1 - 6e-22 77.6 0.9 6e-22 77.6 0.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) AA_permease_2 PF13520.1 EPS33022.1 - 0.0072 14.9 0.9 0.0086 14.6 0.6 1.2 1 0 0 1 1 1 1 Amino acid permease DUF2976 PF11190.3 EPS33022.1 - 0.023 14.1 0.5 0.023 14.1 0.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) COX4_pro_2 PF07835.7 EPS33022.1 - 0.047 13.6 1.1 0.1 12.6 0.0 2.0 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV DUF4063 PF13272.1 EPS33022.1 - 0.075 12.8 0.3 0.13 12.0 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4063) DUF3753 PF12575.3 EPS33022.1 - 0.12 12.2 0.6 13 5.7 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3753) Tetraspannin PF00335.15 EPS33022.1 - 0.14 11.4 2.7 0.28 10.4 1.2 1.8 2 0 0 2 2 2 0 Tetraspanin family Ndc1_Nup PF09531.5 EPS33022.1 - 0.61 8.4 5.6 0.8 8.0 3.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4131 PF13567.1 EPS33022.1 - 3.4 7.0 8.8 1.7 7.9 3.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) MatE PF01554.13 EPS33023.1 - 2.5e-53 180.0 24.4 1.7e-30 105.7 5.1 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 EPS33023.1 - 0.0002 21.1 5.0 0.0002 21.1 3.5 4.1 3 2 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain RPA_C PF08784.6 EPS33024.1 - 1.2e-22 80.2 0.8 2.9e-22 78.9 0.0 2.0 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 EPS33024.1 - 9.9e-05 22.1 0.7 0.00022 21.0 0.5 1.6 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain HIN PF02760.10 EPS33024.1 - 0.11 11.8 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 HIN-200/IF120x domain DEAD PF00270.24 EPS33025.1 - 1.4e-45 154.8 0.0 3.1e-45 153.7 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase DBP10CT PF08147.7 EPS33025.1 - 1.6e-21 75.8 4.7 5.7e-21 74.1 3.2 2.0 1 0 0 1 1 1 1 DBP10CT (NUC160) domain Helicase_C PF00271.26 EPS33025.1 - 2.5e-20 72.1 0.0 6.4e-20 70.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Zn_clus PF00172.13 EPS33028.1 - 0.00045 20.0 9.1 0.00074 19.3 6.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4611 PF15387.1 EPS33029.1 - 0.061 13.4 3.3 0.063 13.4 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Nucleoplasmin PF03066.10 EPS33029.1 - 0.074 12.5 7.1 0.077 12.5 4.9 1.1 1 0 0 1 1 1 0 Nucleoplasmin DUF2457 PF10446.4 EPS33029.1 - 0.079 11.6 4.0 0.07 11.8 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RXT2_N PF08595.6 EPS33029.1 - 0.13 12.0 1.1 0.13 12.0 0.7 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal AA_permease PF00324.16 EPS33030.1 - 3.7e-125 417.9 40.9 4.1e-125 417.8 28.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPS33030.1 - 5.2e-45 153.7 46.7 6.4e-45 153.4 32.4 1.1 1 0 0 1 1 1 1 Amino acid permease MgtE PF01769.11 EPS33030.1 - 0.19 12.0 0.1 0.19 12.0 0.1 3.5 4 0 0 4 4 4 0 Divalent cation transporter DEAD PF00270.24 EPS33031.1 - 1.9e-44 151.1 0.0 3.4e-44 150.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EPS33031.1 - 3.3e-26 90.6 0.2 6.9e-26 89.5 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EPS33031.1 - 4.7e-21 74.4 0.0 1.2e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EPS33031.1 - 0.047 13.4 0.0 0.33 10.7 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain SNF2_N PF00176.18 EPS33031.1 - 0.05 12.3 0.0 0.1 11.3 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain Flavi_DEAD PF07652.9 EPS33031.1 - 0.077 12.7 0.0 0.29 10.8 0.0 1.9 1 1 0 1 1 1 0 Flavivirus DEAD domain DnaJ PF00226.26 EPS33032.1 - 1.6e-14 53.3 1.5 1.6e-14 53.3 1.0 2.6 3 0 0 3 3 3 1 DnaJ domain HSP20 PF00011.16 EPS33032.1 - 0.0016 18.2 1.1 2.1 8.2 0.0 2.6 2 1 0 2 2 2 2 Hsp20/alpha crystallin family DUF4604 PF15377.1 EPS33032.1 - 1.3 9.2 13.8 2.9 8.0 9.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) PAPS_reduct PF01507.14 EPS33033.1 - 1.2e-23 83.8 0.0 2e-22 79.8 0.0 2.5 1 1 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family RRM_1 PF00076.17 EPS33034.1 - 1.7e-26 91.6 0.0 8.4e-14 50.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS33034.1 - 1.1e-18 66.9 0.0 7.3e-08 32.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS33034.1 - 7e-06 25.8 0.4 0.0015 18.3 0.0 2.9 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NAD_binding_2 PF03446.10 EPS33035.1 - 3.1e-34 118.1 0.4 5.3e-34 117.4 0.3 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EPS33035.1 - 1.2e-31 109.2 0.0 3e-31 107.9 0.0 1.7 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EPS33035.1 - 5.5e-05 23.5 0.1 0.00011 22.5 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EPS33035.1 - 0.0035 16.5 0.3 0.07 12.2 0.2 2.2 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain OCD_Mu_crystall PF02423.10 EPS33035.1 - 0.016 14.0 0.2 0.027 13.2 0.2 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family TGS PF02824.16 EPS33035.1 - 0.096 12.5 0.0 0.33 10.8 0.0 1.9 1 1 0 1 1 1 0 TGS domain PQQ PF01011.16 EPS33036.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 PQQ enzyme repeat MOR2-PAG1_N PF14222.1 EPS33037.1 - 3.1e-214 712.7 0.0 6.1e-214 711.7 0.0 1.5 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 EPS33037.1 - 7.3e-94 314.3 0.0 7.3e-94 314.3 0.0 1.9 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 EPS33037.1 - 3e-35 121.1 14.7 9.2e-21 73.2 5.1 3.3 2 1 0 2 2 2 2 Cell morphogenesis central region FAD_binding_1 PF00667.15 EPS33038.1 - 3.1e-61 206.6 0.0 4.5e-61 206.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EPS33038.1 - 8.1e-34 116.6 2.5 1.5e-33 115.8 1.7 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EPS33038.1 - 1.2e-22 80.5 0.1 1.2e-21 77.3 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EPS33038.1 - 0.039 13.9 0.7 0.13 12.2 0.0 2.3 3 0 0 3 3 3 0 Flavodoxin domain Shikimate_DH PF01488.15 EPS33038.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase MMS1_N PF10433.4 EPS33039.1 - 2.2e-89 299.9 0.0 5.1e-89 298.7 0.0 1.6 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 EPS33039.1 - 2.4e-73 247.0 0.4 7.1e-71 238.9 0.1 3.7 4 0 0 4 4 4 1 CPSF A subunit region PQQ_2 PF13360.1 EPS33039.1 - 0.0033 16.9 2.1 0.81 9.0 0.0 3.0 3 1 0 3 3 3 2 PQQ-like domain PGA2 PF07543.7 EPS33040.1 - 1.2e-32 112.5 4.9 1.5e-32 112.2 3.4 1.1 1 0 0 1 1 1 1 Protein trafficking PGA2 Spt5_N PF11942.3 EPS33040.1 - 9.2 6.9 14.0 2.4 8.8 4.7 2.2 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal CENP-S PF15630.1 EPS33041.1 - 1.1e-35 121.6 0.0 1.4e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 EPS33041.1 - 1.1e-05 24.9 0.0 1.5e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 EPS33041.1 - 1.4e-05 24.7 0.0 2.3e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.10 EPS33041.1 - 0.095 12.4 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 EPS33041.1 - 0.14 12.2 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 SUR7 PF06687.7 EPS33043.1 - 0.026 14.0 7.3 0.063 12.8 0.0 2.5 2 1 0 2 2 2 0 SUR7/PalI family GerA PF03323.8 EPS33043.1 - 0.065 11.3 0.7 0.11 10.5 0.5 1.3 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein MIG-14_Wnt-bd PF06664.7 EPS33043.1 - 0.28 9.9 3.2 17 4.1 0.0 2.2 2 0 0 2 2 2 0 Wnt-binding factor required for Wnt secretion EphA2_TM PF14575.1 EPS33043.1 - 0.32 11.4 4.1 1.3 9.5 0.0 2.7 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain MARVEL PF01284.18 EPS33043.1 - 0.66 9.7 19.3 1.6 8.5 13.3 1.7 1 1 0 1 1 1 0 Membrane-associating domain Pkinase PF00069.20 EPS33045.1 - 8.7e-32 110.2 0.0 3.6e-31 108.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS33045.1 - 1.3e-12 47.3 0.0 3.4e-05 23.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase UvdE PF03851.9 EPS33046.1 - 2.7e-111 371.0 0.0 3.5e-111 370.6 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE DUF2183 PF09949.4 EPS33047.1 - 1.4e-33 114.7 0.0 3.2e-33 113.6 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) LNS2 PF08235.8 EPS33047.1 - 0.045 13.3 0.0 0.082 12.4 0.0 1.4 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) Acyl-CoA_dh_1 PF00441.19 EPS33048.1 - 2.5e-31 108.7 1.4 5.2e-31 107.7 1.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 EPS33048.1 - 2.8e-20 71.8 0.0 8.6e-20 70.3 0.0 1.9 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 EPS33048.1 - 6.4e-19 67.2 0.3 1.4e-18 66.0 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EPS33048.1 - 3.2e-07 30.8 0.1 1.1e-06 29.2 0.1 2.0 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EPS33048.1 - 0.00078 19.6 0.0 0.0019 18.4 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Tn916-Xis PF09035.5 EPS33048.1 - 0.041 13.9 0.0 0.098 12.7 0.0 1.6 1 0 0 1 1 1 0 Excisionase from transposon Tn916 PI31_Prot_N PF11566.3 EPS33049.1 - 4.8e-37 126.9 0.0 5.7e-37 126.6 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 EPS33049.1 - 2.6e-16 60.0 20.1 2.6e-16 60.0 14.0 2.8 3 1 0 3 3 3 1 PI31 proteasome regulator NmrA PF05368.8 EPS33050.1 - 1.5e-34 119.2 0.1 2e-34 118.8 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPS33050.1 - 3.1e-15 56.6 0.0 4.3e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPS33050.1 - 2e-10 40.5 0.0 3e-09 36.6 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPS33050.1 - 5.4e-08 31.8 0.1 8.1e-08 31.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EPS33050.1 - 6.7e-07 29.3 0.1 1.4e-06 28.3 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPS33050.1 - 1.7e-06 27.8 0.1 5e-06 26.2 0.0 1.9 1 1 1 2 2 2 1 KR domain NAD_binding_4 PF07993.7 EPS33050.1 - 0.00038 19.4 0.0 0.0029 16.5 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein F420_oxidored PF03807.12 EPS33050.1 - 0.0004 20.7 0.1 0.0077 16.6 0.0 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 EPS33050.1 - 0.00053 18.9 0.1 0.0028 16.6 0.1 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein DapB_N PF01113.15 EPS33050.1 - 0.0052 16.6 0.0 0.017 15.0 0.0 1.8 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 EPS33050.1 - 0.0088 16.3 0.1 0.04 14.2 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EPS33050.1 - 0.036 13.0 0.0 0.054 12.4 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase RmlD_sub_bind PF04321.12 EPS33050.1 - 0.081 11.7 0.0 0.44 9.4 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain Mur_ligase PF01225.20 EPS33050.1 - 0.11 12.5 0.5 0.55 10.3 0.1 2.1 2 0 0 2 2 2 0 Mur ligase family, catalytic domain Metallophos PF00149.23 EPS33051.1 - 7.8e-44 149.4 0.8 1e-43 149.1 0.5 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3112 PF11309.3 EPS33052.1 - 6.6e-45 152.7 13.2 2.8e-42 144.2 1.8 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) MFS_1 PF07690.11 EPS33054.1 - 5.1e-58 196.4 41.3 5.2e-50 170.1 10.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EPS33054.1 - 7.7e-07 27.5 0.2 0.0056 14.7 0.0 2.8 2 2 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.8 EPS33054.1 - 0.00051 18.3 8.8 0.00051 18.3 6.1 2.3 2 0 0 2 2 2 2 Transmembrane secretion effector Mem_trans PF03547.13 EPS33054.1 - 0.0074 14.6 0.4 0.024 12.9 0.0 1.9 2 0 0 2 2 2 1 Membrane transport protein DUF2754 PF10953.3 EPS33054.1 - 0.75 9.8 0.0 0.75 9.8 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2754) HAD_2 PF13419.1 EPS33055.1 - 8.1e-13 48.9 0.0 1.3e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EPS33055.1 - 6.3e-05 22.6 0.0 0.00017 21.2 0.0 1.9 2 1 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 EPS33055.1 - 0.00065 20.1 0.0 0.081 13.3 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NT5C PF06941.7 EPS33055.1 - 0.046 13.2 0.0 0.21 11.0 0.0 1.8 1 1 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) WD40 PF00400.27 EPS33056.1 - 1.5e-08 34.2 6.0 0.94 9.4 0.0 7.4 8 0 0 8 8 8 4 WD domain, G-beta repeat Lactonase PF10282.4 EPS33056.1 - 0.027 13.5 0.0 0.052 12.6 0.0 1.4 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Nucleoporin_FG PF13634.1 EPS33057.1 - 1.4e-14 54.2 100.2 3.6e-09 36.8 35.8 3.3 1 1 2 3 3 3 3 Nucleoporin FG repeat region DUF1664 PF07889.7 EPS33057.1 - 0.17 11.6 0.4 0.63 9.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Cpn10 PF00166.16 EPS33058.1 - 8.7e-27 92.9 0.0 9.7e-27 92.7 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Fip1 PF05182.8 EPS33059.1 - 4e-20 70.8 1.9 7.2e-20 69.9 1.3 1.4 1 0 0 1 1 1 1 Fip1 motif XAP5 PF04921.9 EPS33060.1 - 7.3e-79 264.6 0.3 1.4e-78 263.7 0.0 1.5 2 0 0 2 2 2 1 XAP5, circadian clock regulator DUF4604 PF15377.1 EPS33060.1 - 0.017 15.3 4.9 0.017 15.3 3.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) LigD_N PF13298.1 EPS33060.1 - 0.02 14.9 0.0 0.041 13.9 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase Ligase (LigD) zf-RING_5 PF14634.1 EPS33061.1 - 1.1e-08 34.7 8.1 1.9e-08 33.8 5.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EPS33061.1 - 0.00027 20.9 6.1 0.0003 20.7 3.3 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPS33061.1 - 0.00028 20.6 8.3 0.00062 19.5 5.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EPS33061.1 - 0.0048 16.5 10.0 0.0091 15.6 7.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EPS33061.1 - 0.0097 15.7 5.8 0.025 14.4 4.0 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EPS33061.1 - 0.013 15.0 7.7 0.033 13.8 5.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TMF_TATA_bd PF12325.3 EPS33061.1 - 0.024 14.3 3.7 0.039 13.6 2.5 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding zf-RING_UBOX PF13445.1 EPS33061.1 - 0.036 13.7 1.5 0.036 13.7 1.0 2.0 1 1 0 1 1 1 0 RING-type zinc-finger DUF1732 PF08340.6 EPS33061.1 - 0.051 13.3 0.3 0.11 12.2 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1732) Viral_P18 PF04521.8 EPS33061.1 - 0.063 12.7 2.5 0.096 12.1 1.4 1.5 1 1 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein zf-RING_4 PF14570.1 EPS33061.1 - 0.084 12.4 2.4 0.17 11.4 1.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF948 PF06103.6 EPS33061.1 - 0.099 12.5 2.2 0.19 11.5 1.5 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DZR PF12773.2 EPS33061.1 - 0.11 12.3 5.5 0.3 10.9 3.8 1.8 1 1 0 1 1 1 0 Double zinc ribbon IncA PF04156.9 EPS33061.1 - 0.15 11.6 3.6 0.23 11.0 2.5 1.2 1 0 0 1 1 1 0 IncA protein zf-RING_3 PF14369.1 EPS33061.1 - 0.19 11.7 1.7 0.44 10.5 1.1 1.6 1 0 0 1 1 1 0 zinc-finger zf-MIZ PF02891.15 EPS33061.1 - 0.29 10.6 6.3 0.62 9.6 4.4 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_6 PF14835.1 EPS33061.1 - 0.33 10.7 6.8 0.8 9.5 4.7 1.6 1 1 0 1 1 1 0 zf-RING of BARD1-type protein DUF972 PF06156.8 EPS33061.1 - 0.36 11.1 4.0 0.77 10.1 2.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Spc24 PF08286.6 EPS33061.1 - 0.38 10.4 3.8 0.62 9.7 2.6 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 C1_4 PF07975.7 EPS33061.1 - 0.4 10.7 6.5 4.4 7.3 2.0 2.7 2 0 0 2 2 2 0 TFIIH C1-like domain zf-rbx1 PF12678.2 EPS33061.1 - 0.88 9.7 5.1 2 8.5 3.6 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger RTA1 PF04479.8 EPS33062.1 - 2.4e-36 125.3 6.6 3.9e-36 124.6 4.6 1.3 1 0 0 1 1 1 1 RTA1 like protein Fungal_trans_2 PF11951.3 EPS33063.1 - 1.1e-39 136.0 2.9 1.3e-39 135.8 2.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS33063.1 - 6.5e-06 25.9 8.9 1.3e-05 24.9 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cys_Met_Meta_PP PF01053.15 EPS33064.1 - 7.4e-60 202.2 0.0 2e-59 200.8 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EPS33064.1 - 0.0022 17.0 0.0 0.0036 16.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EPS33064.1 - 0.0069 15.1 0.0 0.034 12.9 0.0 2.0 2 1 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EPS33064.1 - 0.092 11.7 0.0 0.76 8.7 0.0 2.3 3 0 0 3 3 3 0 DegT/DnrJ/EryC1/StrS aminotransferase family TRI5 PF06330.6 EPS33065.1 - 9.7e-12 44.2 0.5 1.2e-11 43.8 0.3 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Con-6 PF10346.4 EPS33067.1 - 7.5e-42 140.4 13.4 3.2e-16 58.4 0.1 3.7 4 0 0 4 4 4 3 Conidiation protein 6 SpoIIIAH PF12685.2 EPS33067.1 - 0.25 10.8 4.8 2.7 7.4 0.3 2.6 3 0 0 3 3 3 0 SpoIIIAH-like protein Transposase_mut PF00872.13 EPS33068.1 - 0.052 12.0 0.0 0.06 11.8 0.0 1.1 1 0 0 1 1 1 0 Transposase, Mutator family DUF3328 PF11807.3 EPS33069.1 - 9.9e-31 107.1 0.1 1.1e-30 106.9 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) NAD_binding_4 PF07993.7 EPS33070.1 - 2.3e-32 111.8 0.0 3.7e-32 111.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EPS33070.1 - 3.1e-11 42.3 0.0 7.2e-11 41.1 0.0 1.5 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.16 EPS33070.1 - 1.4e-08 34.5 0.0 3.7e-08 33.0 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EPS33070.1 - 5.1e-07 29.8 0.0 9.7e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site NAD_binding_10 PF13460.1 EPS33070.1 - 0.0089 16.0 0.1 3 7.8 0.0 2.7 2 0 0 2 2 2 2 NADH(P)-binding 3Beta_HSD PF01073.14 EPS33070.1 - 0.027 13.1 0.0 4.5 5.8 0.0 3.1 3 0 0 3 3 3 0 3-beta hydroxysteroid dehydrogenase/isomerase family Aldo_ket_red PF00248.16 EPS33071.1 - 5.9e-46 156.5 0.0 7.2e-46 156.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Lipase_GDSL_2 PF13472.1 EPS33072.1 - 1.1e-16 61.4 0.7 1.6e-16 60.9 0.5 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EPS33072.1 - 1.3e-11 44.7 0.0 3.8e-11 43.2 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Sugar_tr PF00083.19 EPS33073.1 - 5.7e-71 239.4 20.4 6.6e-71 239.2 14.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS33073.1 - 1.5e-26 92.9 25.2 1.4e-18 66.7 5.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EPS33073.1 - 0.00024 19.4 3.5 0.00024 19.4 2.4 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) VHP PF02209.14 EPS33073.1 - 0.064 12.9 0.8 0.15 11.7 0.6 1.5 1 0 0 1 1 1 0 Villin headpiece domain Glyco_hydro_43 PF04616.9 EPS33074.1 - 5.3e-81 271.8 0.2 7.3e-81 271.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Toxin_54 PF15533.1 EPS33074.1 - 0.1 12.9 0.1 0.4 10.9 0.0 1.9 2 0 0 2 2 2 0 Putative toxin 54 Glyco_hydro_3 PF00933.16 EPS33075.1 - 3.8e-63 213.2 0.0 6.1e-63 212.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EPS33075.1 - 3.3e-47 160.9 0.1 5.1e-47 160.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain WSC PF01822.14 EPS33075.1 - 9.1e-17 60.7 4.6 1.8e-16 59.8 3.2 1.5 1 0 0 1 1 1 1 WSC domain BNR_2 PF13088.1 EPS33076.1 - 4.7e-05 22.8 0.2 0.15 11.3 0.1 2.2 2 0 0 2 2 2 2 BNR repeat-like domain BNR PF02012.15 EPS33076.1 - 0.97 9.5 18.8 0.084 12.7 1.5 4.0 4 0 0 4 4 4 0 BNR/Asp-box repeat Acetyltransf_10 PF13673.1 EPS33077.1 - 1.6e-06 28.2 0.3 7.1e-06 26.1 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPS33077.1 - 1.4e-05 25.0 0.2 3e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EPS33077.1 - 0.00016 21.7 0.0 0.00029 20.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 EPS33077.1 - 0.0083 15.7 0.0 0.025 14.1 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EPS33077.1 - 0.049 13.5 0.1 0.14 12.0 0.0 1.7 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Pho86 PF11124.3 EPS33077.1 - 0.13 11.1 0.1 0.24 10.3 0.1 1.3 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 Sugar_tr PF00083.19 EPS33078.1 - 4.1e-44 150.9 21.5 2.4e-43 148.3 14.9 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS33078.1 - 8e-21 74.1 26.6 8e-21 74.1 18.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS33079.1 - 1.8e-09 36.7 3.6 2.3e-09 36.3 2.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF4203 PF13886.1 EPS33079.1 - 0.13 11.6 4.7 0.1 12.0 2.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4203) Aa_trans PF01490.13 EPS33080.1 - 5.4e-55 186.5 37.6 6.1e-55 186.3 26.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DHDPS PF00701.17 EPS33082.1 - 3.4e-40 137.4 0.0 4.4e-40 137.1 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family MFS_1 PF07690.11 EPS33083.1 - 1.1e-37 129.5 40.8 1.1e-37 129.5 28.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Chitin_synth_1 PF01644.12 EPS33084.1 - 1.7e-68 229.5 0.1 2.5e-68 229.0 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EPS33084.1 - 2e-26 91.5 0.0 5.7e-26 90.0 0.0 1.8 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EPS33084.1 - 1.2e-21 76.7 0.0 1.3e-19 69.9 0.0 2.1 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EPS33084.1 - 6.3e-12 45.6 0.1 6.3e-12 45.6 0.0 2.9 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EPS33084.1 - 1.4e-09 38.1 0.0 4e-09 36.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 PACT_coil_coil PF10495.4 EPS33084.1 - 0.089 12.7 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein Cyclase PF04199.8 EPS33085.1 - 1.4e-16 60.6 0.0 2.1e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Amidase_2 PF01510.20 EPS33085.1 - 0.016 15.2 0.1 0.023 14.7 0.1 1.3 1 0 0 1 1 1 0 N-acetylmuramoyl-L-alanine amidase Fungal_trans PF04082.13 EPS33086.1 - 9.2e-19 67.3 0.5 2e-18 66.1 0.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS33086.1 - 1.8e-06 27.7 7.2 3.2e-06 26.9 5.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hydantoinase_B PF02538.9 EPS33087.1 - 2e-187 623.6 0.0 2.5e-187 623.2 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EPS33087.1 - 9e-93 310.5 0.0 1.3e-91 306.6 0.0 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EPS33087.1 - 2.4e-55 186.7 0.1 9.3e-53 178.3 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region His_Phos_1 PF00300.17 EPS33088.1 - 8.5e-09 35.6 0.0 5.6e-07 29.7 0.0 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) 5_nucleotid_C PF02872.13 EPS33089.1 - 8.8e-37 126.4 0.0 3.6e-36 124.4 0.0 1.9 2 0 0 2 2 2 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EPS33089.1 - 2e-07 30.5 0.1 3.8e-07 29.6 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Apc3 PF12895.2 EPS33090.1 - 0.25 11.5 2.0 2 8.5 0.7 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 FMO-like PF00743.14 EPS33091.1 - 1.5e-23 82.8 0.0 4.5e-23 81.2 0.0 1.7 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EPS33091.1 - 4.3e-21 75.9 0.0 1.3e-20 74.3 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EPS33091.1 - 9.6e-12 44.4 0.0 1.2e-08 34.3 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EPS33091.1 - 5.7e-11 42.6 0.0 1.1e-07 32.0 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPS33091.1 - 1.3e-07 31.5 1.8 8.1e-06 25.7 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EPS33091.1 - 1.1e-06 28.4 1.9 0.0023 17.7 0.4 3.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EPS33091.1 - 1.3e-05 25.3 0.0 0.069 13.2 0.0 2.9 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 EPS33091.1 - 2e-05 24.9 6.1 0.047 14.1 0.1 2.6 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EPS33091.1 - 0.00016 20.6 0.3 0.00038 19.4 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 EPS33091.1 - 0.00074 19.2 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EPS33091.1 - 0.00085 19.5 0.0 0.058 13.6 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 EPS33091.1 - 0.01 15.3 0.1 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 EPS33091.1 - 0.06 11.8 1.9 0.48 8.8 0.1 2.6 3 0 0 3 3 3 0 HI0933-like protein 2-Hacid_dh_C PF02826.14 EPS33091.1 - 0.15 11.2 0.0 8.1 5.5 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 EPS33091.1 - 2.2 7.0 5.3 0.16 10.8 0.4 1.5 2 0 0 2 2 2 0 FAD binding domain DUF2165 PF09933.4 EPS33092.1 - 0.021 14.5 0.4 0.043 13.5 0.3 1.4 1 0 0 1 1 1 0 Predicted small integral membrane protein (DUF2165) Sas10_Utp3 PF04000.10 EPS33093.1 - 3.1e-15 56.1 0.5 8.6e-15 54.7 0.3 1.8 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Daxx PF03344.10 EPS33093.1 - 0.0024 16.4 17.7 0.0036 15.8 12.3 1.3 1 0 0 1 1 1 1 Daxx Family NOA36 PF06524.7 EPS33093.1 - 0.38 9.9 10.0 0.76 8.9 6.9 1.4 1 0 0 1 1 1 0 NOA36 protein Myc_N PF01056.13 EPS33093.1 - 0.7 8.9 15.4 0.19 10.8 7.1 2.2 2 0 0 2 2 2 0 Myc amino-terminal region Ycf1 PF05758.7 EPS33093.1 - 1.4 6.5 5.2 1.5 6.4 3.6 1.2 1 0 0 1 1 1 0 Ycf1 CENP-B_dimeris PF09026.5 EPS33093.1 - 8.8 6.6 18.5 2.7 8.2 9.9 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain EMP70 PF02990.11 EPS33094.1 - 1.2e-189 631.1 0.1 1.7e-189 630.6 0.1 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 NfeD PF01957.13 EPS33094.1 - 0.044 13.9 0.0 0.044 13.9 0.0 4.0 3 2 0 3 3 3 0 NfeD-like C-terminal, partner-binding EF-hand_7 PF13499.1 EPS33095.1 - 4.1e-29 100.5 11.3 1.5e-13 50.6 0.6 3.2 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 EPS33095.1 - 5.1e-26 87.9 11.4 4.9e-08 31.7 0.1 4.8 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 EPS33095.1 - 3.5e-25 85.5 3.1 5.8e-06 25.7 0.0 5.1 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 EPS33095.1 - 1.1e-17 62.4 11.9 8.9e-05 21.6 0.0 4.8 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.1 EPS33095.1 - 1.3e-15 56.7 12.2 5.4e-06 25.9 1.2 4.3 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 EPS33095.1 - 3.7e-09 36.2 6.3 0.002 17.8 0.1 3.8 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EPS33095.1 - 0.00011 22.0 0.4 0.058 13.3 0.0 3.3 2 1 1 3 3 3 1 EF-hand domain EF-hand_10 PF14788.1 EPS33095.1 - 0.00065 19.3 2.0 0.58 9.8 0.0 3.9 4 0 0 4 4 4 1 EF hand SPARC_Ca_bdg PF10591.4 EPS33095.1 - 0.024 14.6 1.2 1.5 8.8 0.1 3.0 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF1679 PF07914.6 EPS33095.1 - 0.026 13.1 0.4 2.1 6.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) EF-hand_2 PF09068.6 EPS33095.1 - 0.05 13.6 0.1 5.6 7.0 0.0 3.1 3 1 1 4 4 4 0 EF hand DAG_kinase_N PF14513.1 EPS33095.1 - 0.28 11.3 2.9 0.48 10.6 1.7 1.5 1 1 0 1 1 1 0 Diacylglycerol kinase N-terminus Kinesin PF00225.18 EPS33096.1 - 7.1e-111 370.1 0.1 2.1e-110 368.5 0.0 1.8 1 0 0 1 1 1 1 Kinesin motor domain DUF972 PF06156.8 EPS33096.1 - 0.97 9.8 40.0 0.44 10.9 7.7 5.8 2 2 3 5 5 5 0 Protein of unknown function (DUF972) UQ_con PF00179.21 EPS33097.1 - 2.4e-51 172.8 0.0 2.7e-51 172.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EPS33097.1 - 1.6e-05 24.6 0.0 1.9e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EPS33097.1 - 0.055 13.3 0.1 0.12 12.2 0.1 1.7 1 1 0 1 1 1 0 RWD domain Thiolase_N PF00108.18 EPS33098.1 - 6.6e-97 323.6 0.2 1.1e-96 322.8 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EPS33098.1 - 2e-38 130.5 1.4 2e-38 130.5 1.0 1.9 2 1 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EPS33098.1 - 3.5e-05 23.4 2.0 4e-05 23.2 0.3 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain TFIIIC_delta PF12657.2 EPS33099.1 - 2.6e-39 134.7 0.2 4.7e-39 133.8 0.1 1.5 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 EPS33099.1 - 1.5e-28 98.5 1.7 3e-28 97.6 1.2 1.5 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex Glyco_trans_1_4 PF13692.1 EPS33100.1 - 1.2e-27 96.7 0.0 1.1e-26 93.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 EPS33100.1 - 1.4e-05 24.6 0.0 6.5e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EPS33100.1 - 0.00038 20.6 0.0 0.0012 18.9 0.0 1.9 1 1 1 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EPS33100.1 - 0.0045 17.2 0.0 0.0088 16.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Cation_efflux PF01545.16 EPS33101.1 - 5.5e-53 179.8 10.4 5.5e-53 179.8 7.2 2.9 3 0 0 3 3 3 1 Cation efflux family Zip PF02535.17 EPS33101.1 - 0.045 12.7 0.2 0.045 12.7 0.1 6.2 4 2 2 6 6 6 0 ZIP Zinc transporter NAD_binding_4 PF07993.7 EPS33102.1 - 1.4e-33 115.9 0.0 1.8e-33 115.5 0.0 1.1 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EPS33102.1 - 2.6e-05 23.2 0.0 3.6e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EPS33102.1 - 0.068 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Zn_clus PF00172.13 EPS33103.1 - 1.2e-09 37.9 10.7 2.1e-09 37.1 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EPS33103.1 - 5.3e-05 21.9 0.2 9e-05 21.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.8 EPS33105.1 - 7.5e-43 146.6 0.6 1.1e-42 146.1 0.4 1.1 1 0 0 1 1 1 1 RTA1 like protein UQ_con PF00179.21 EPS33106.1 - 3.1e-44 149.7 0.0 3.6e-44 149.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EPS33106.1 - 0.048 13.4 0.1 0.09 12.5 0.1 1.7 1 1 0 1 1 1 0 Prokaryotic E2 family B Amino_oxidase PF01593.19 EPS33108.1 - 7.5e-19 68.1 0.1 7.4e-18 64.8 0.1 2.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EPS33108.1 - 1.5e-14 53.7 0.0 3.8e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EPS33108.1 - 4.2e-14 52.2 5.1 1.1e-12 47.5 3.5 2.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EPS33108.1 - 5.9e-08 31.5 0.2 0.00026 19.5 0.6 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.2 EPS33108.1 - 1.8e-06 27.3 0.0 2.9e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EPS33108.1 - 2e-06 28.0 1.7 0.0067 16.8 0.8 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPS33108.1 - 2.5e-06 27.5 0.0 1.1e-05 25.4 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EPS33108.1 - 4.6e-06 25.7 5.8 2.7e-05 23.2 2.9 2.3 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EPS33108.1 - 5.9e-06 26.4 0.0 0.0004 20.5 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPS33108.1 - 0.00041 19.5 0.7 0.00069 18.7 0.5 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 EPS33108.1 - 0.0013 17.8 0.5 0.0071 15.4 0.3 2.1 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.17 EPS33108.1 - 0.0019 17.1 0.0 0.0039 16.1 0.0 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A GDI PF00996.13 EPS33108.1 - 0.0021 16.4 0.1 0.096 10.9 0.0 2.2 2 0 0 2 2 2 1 GDP dissociation inhibitor NAD_binding_9 PF13454.1 EPS33108.1 - 0.0027 17.4 0.5 0.096 12.4 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding ApbA PF02558.11 EPS33108.1 - 0.028 13.8 0.6 0.051 13.0 0.4 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.7 EPS33108.1 - 0.039 12.8 0.1 0.11 11.4 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.9 EPS33108.1 - 0.04 12.5 3.3 2.7 6.4 1.1 2.3 2 0 0 2 2 2 0 Tryptophan halogenase 3HCDH_N PF02737.13 EPS33108.1 - 0.06 12.9 0.9 0.1 12.2 0.7 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EPS33108.1 - 0.13 12.5 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.13 EPS33108.1 - 0.15 12.0 0.2 0.29 11.1 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain SQS_PSY PF00494.14 EPS33109.1 - 6.6e-55 186.2 0.1 8.3e-55 185.9 0.1 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase DUF3654 PF12376.3 EPS33109.1 - 0.035 13.9 0.0 0.065 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3654) Amino_oxidase PF01593.19 EPS33110.1 - 1.8e-24 86.6 0.1 3e-24 85.9 0.1 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EPS33110.1 - 2.6e-13 49.7 0.1 7.3e-13 48.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EPS33110.1 - 3.8e-12 45.7 1.1 1.4e-10 40.6 0.7 2.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EPS33110.1 - 3.2e-07 29.1 0.5 0.00071 18.1 0.6 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.2 EPS33110.1 - 7.5e-07 28.5 0.0 1.6e-06 27.5 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EPS33110.1 - 1.2e-06 28.5 0.1 4.2e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EPS33110.1 - 9.5e-06 24.6 1.7 2.4e-05 23.4 0.8 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EPS33110.1 - 4.2e-05 23.7 0.1 0.012 15.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPS33110.1 - 0.00011 22.5 0.1 0.0052 17.1 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.13 EPS33110.1 - 0.00086 17.7 0.0 0.45 8.7 0.0 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor AlaDh_PNT_C PF01262.16 EPS33110.1 - 0.0016 18.0 0.1 0.0045 16.5 0.0 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 EPS33110.1 - 0.005 15.7 3.3 0.0055 15.6 0.8 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.12 EPS33110.1 - 0.011 14.8 0.1 0.024 13.7 0.1 1.5 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 EPS33110.1 - 0.025 14.3 2.7 0.1 12.3 0.1 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding IlvN PF07991.7 EPS33110.1 - 0.033 13.5 0.1 0.056 12.8 0.1 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.14 EPS33110.1 - 0.042 12.9 0.1 0.55 9.3 0.1 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EPS33110.1 - 0.056 13.0 0.3 0.056 13.0 0.2 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FMO-like PF00743.14 EPS33110.1 - 0.086 11.0 0.3 0.12 10.4 0.2 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like FAD_binding_3 PF01494.14 EPS33110.1 - 0.1 11.6 1.3 0.14 11.1 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain RPE65 PF03055.10 EPS33111.1 - 1.9e-126 422.5 0.0 2.2e-126 422.3 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Mito_carr PF00153.22 EPS33112.1 - 2.8e-60 200.0 5.9 9.4e-21 73.3 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CFEM PF05730.6 EPS33113.1 - 5.9e-11 42.0 9.8 1.2e-10 41.0 6.8 1.5 1 0 0 1 1 1 1 CFEM domain Big_3_3 PF13750.1 EPS33113.1 - 1.6 8.1 6.9 3.3 7.1 4.8 1.6 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 3) HET PF06985.6 EPS33115.1 - 1.6e-08 34.7 3.9 8.3e-07 29.2 0.3 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) PAN_1 PF00024.21 EPS33119.1 - 6.3e-06 25.8 0.3 7.3e-06 25.6 0.2 1.1 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.1 EPS33119.1 - 5.2e-05 22.8 1.0 7.1e-05 22.4 0.7 1.2 1 0 0 1 1 1 1 PAN domain MANEC PF07502.9 EPS33119.1 - 0.011 15.7 0.6 0.012 15.5 0.4 1.1 1 0 0 1 1 1 0 MANEC domain PAN_2 PF08276.6 EPS33119.1 - 0.053 13.3 1.0 0.068 13.0 0.7 1.2 1 0 0 1 1 1 0 PAN-like domain PAN_3 PF08277.7 EPS33119.1 - 0.065 12.8 0.4 0.083 12.5 0.3 1.3 1 0 0 1 1 1 0 PAN-like domain DUF4360 PF14273.1 EPS33119.1 - 0.088 12.4 0.0 0.097 12.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4360) COesterase PF00135.23 EPS33120.1 - 2.2e-85 287.3 0.0 2.8e-85 287.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EPS33120.1 - 1.2e-09 38.0 0.2 4.9e-09 36.0 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EPS33120.1 - 0.00038 19.2 0.0 0.37 9.3 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 EPS33120.1 - 0.0079 15.4 0.8 0.015 14.4 0.5 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Med4 PF10018.4 EPS33121.1 - 2.8e-38 131.2 0.7 2.8e-38 131.2 0.5 1.6 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 Zn_clus PF00172.13 EPS33122.1 - 1.9e-08 34.0 11.6 3.6e-08 33.1 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EPS33122.1 - 0.003 16.2 0.2 0.006 15.2 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF3348 PF11828.3 EPS33122.1 - 0.071 12.5 0.1 0.37 10.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3348) Glyco_hydro_92 PF07971.7 EPS33123.1 - 3e-173 577.0 0.3 3.8e-173 576.7 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Bac_rhamnosid PF05592.6 EPS33123.1 - 0.045 11.9 0.0 0.068 11.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase RabGAP-TBC PF00566.13 EPS33124.1 - 8.6e-49 165.8 1.0 2.3e-48 164.4 0.0 2.3 3 0 0 3 3 3 1 Rab-GTPase-TBC domain DNA_topoisoIV PF00521.15 EPS33125.1 - 4.8e-135 450.6 0.2 9.1e-135 449.7 0.2 1.5 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EPS33125.1 - 4.4e-34 117.1 1.0 1.1e-33 115.8 0.7 1.7 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 EPS33125.1 - 2.2e-14 53.2 0.1 9.7e-14 51.1 0.0 2.2 2 0 0 2 2 2 1 Toprim domain HATPase_c PF02518.21 EPS33125.1 - 1.3e-10 40.9 0.0 2.8e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cytochrome_CBB3 PF13442.1 EPS33127.1 - 0.058 13.5 0.1 0.082 13.0 0.1 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III DUF2024 PF09630.5 EPS33127.1 - 0.71 9.6 3.2 0.62 9.8 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF2024) Reticulon PF02453.12 EPS33128.1 - 1.7e-35 122.0 2.6 2.6e-35 121.4 1.8 1.3 1 0 0 1 1 1 1 Reticulon Cytochrome-c551 PF10643.4 EPS33128.1 - 0.054 12.7 0.0 0.09 12.0 0.0 1.4 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 MRP-S28 PF10213.4 EPS33128.1 - 0.094 12.8 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal subunit protein Trypan_PARP PF05887.6 EPS33128.1 - 8.5 6.1 15.1 17 5.2 10.4 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) INCENP_ARK-bind PF03941.10 EPS33129.1 - 1.9e-18 66.0 0.9 8e-18 64.0 0.6 2.2 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region PDZ_1 PF12812.2 EPS33130.1 - 1.1e-53 178.9 0.0 1.3e-33 114.7 0.0 2.6 2 0 0 2 2 2 2 PDZ-like domain Trypsin_2 PF13365.1 EPS33130.1 - 3.2e-15 56.1 0.3 1.5e-14 53.9 0.0 2.2 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_2 PF13180.1 EPS33130.1 - 1.3e-10 41.0 0.0 3.6e-05 23.5 0.0 4.1 4 0 0 4 4 4 2 PDZ domain PDZ PF00595.19 EPS33130.1 - 1.3e-08 34.8 0.0 0.00076 19.6 0.0 3.7 3 0 0 3 3 3 2 PDZ domain (Also known as DHR or GLGF) Trypsin PF00089.21 EPS33130.1 - 3.8e-05 23.3 0.0 0.00015 21.4 0.0 2.0 1 1 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.1 EPS33130.1 - 0.0041 16.8 0.9 0.1 12.4 0.1 3.2 4 0 0 4 4 4 1 Tricorn protease PDZ domain Peptidase_S7 PF00949.16 EPS33130.1 - 0.027 13.8 0.0 0.061 12.7 0.0 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease DUF31 PF01732.11 EPS33130.1 - 0.099 11.9 0.2 0.15 11.3 0.1 1.2 1 0 0 1 1 1 0 Putative peptidase (DUF31) Peptidase_S46 PF10459.4 EPS33130.1 - 0.13 10.6 0.2 0.25 9.6 0.1 1.4 2 0 0 2 2 2 0 Peptidase S46 SSXT PF05030.7 EPS33131.1 - 3.3e-05 23.3 0.0 0.19 11.3 0.0 2.4 2 0 0 2 2 2 2 SSXT protein (N-terminal region) Glyco_hydro_10 PF00331.15 EPS33132.1 - 7.8e-101 337.2 1.5 9e-101 337.0 1.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.13 EPS33132.1 - 1.5e-14 53.3 14.4 5.7e-14 51.4 9.9 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain Toxin_7 PF05980.7 EPS33132.1 - 0.15 12.1 4.4 0.34 10.9 3.0 1.6 1 0 0 1 1 1 0 Toxin 7 TPR_11 PF13414.1 EPS33133.1 - 8e-12 44.6 6.0 2.9e-08 33.2 1.1 2.5 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 EPS33133.1 - 2.2e-09 36.4 1.6 0.0014 18.1 0.0 4.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 EPS33133.1 - 2.3e-08 33.3 0.5 0.0059 16.4 0.0 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EPS33133.1 - 0.00011 22.7 0.0 0.00057 20.4 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EPS33133.1 - 0.0037 17.3 0.2 0.12 12.6 0.0 3.2 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF3808 PF10300.4 EPS33133.1 - 0.0041 15.7 0.2 0.0064 15.1 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) Apc3 PF12895.2 EPS33133.1 - 0.0059 16.7 0.5 0.012 15.6 0.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EPS33133.1 - 0.016 15.5 1.3 0.03 14.6 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EPS33133.1 - 0.022 15.3 0.1 0.12 13.0 0.1 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Pox_T4_N PF04491.7 EPS33133.1 - 0.098 12.4 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Poxvirus T4 protein, N terminus Iso_dh PF00180.15 EPS33134.1 - 2.7e-102 342.3 0.0 4.1e-102 341.6 0.0 1.3 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Nup54 PF13874.1 EPS33135.1 - 0.026 14.1 2.0 0.055 13.1 1.4 1.5 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 CCDC32 PF14989.1 EPS33135.1 - 0.44 10.3 2.9 0.88 9.3 0.1 2.5 3 0 0 3 3 3 0 Coiled-coil domain containing 32 peroxidase PF00141.18 EPS33136.1 - 3.5e-46 157.5 0.0 5.2e-46 156.9 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Ribosomal_S13 PF00416.17 EPS33138.1 - 7.7e-42 142.0 1.8 9.3e-42 141.8 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EPS33138.1 - 0.0045 15.5 0.0 0.0045 15.5 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) DUF1822 PF08852.6 EPS33138.1 - 0.0092 14.8 0.0 0.012 14.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1822) DUF2746 PF10874.3 EPS33138.1 - 0.018 15.1 0.2 1.7 8.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) HHH_6 PF14579.1 EPS33138.1 - 0.063 13.3 0.1 0.15 12.1 0.1 1.7 1 1 0 1 1 1 0 Helix-hairpin-helix motif PP28 PF10252.4 EPS33138.1 - 0.13 12.2 0.3 0.29 11.1 0.2 1.6 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 Peptidase_S10 PF00450.17 EPS33139.1 - 1.8e-130 435.8 0.9 2.2e-130 435.5 0.7 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.6 EPS33139.1 - 3.2e-10 40.1 0.0 2.2e-09 37.4 0.0 2.1 1 1 0 1 1 1 1 Carboxypeptidase Y pro-peptide Abhydrolase_6 PF12697.2 EPS33139.1 - 0.0022 17.9 0.0 0.027 14.3 0.0 2.6 3 0 0 3 3 3 1 Alpha/beta hydrolase family Phasin PF05597.6 EPS33139.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) SBDS_C PF09377.5 EPS33140.1 - 9.3e-52 173.9 0.0 1.4e-51 173.4 0.0 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 EPS33140.1 - 1.9e-26 91.6 0.1 4.1e-26 90.6 0.0 1.6 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Ribosomal_60s PF00428.14 EPS33140.1 - 0.0032 17.8 1.2 0.14 12.5 0.2 2.7 2 0 0 2 2 2 1 60s Acidic ribosomal protein BAF1_ABF1 PF04684.8 EPS33140.1 - 3.4 6.4 6.2 6 5.5 0.2 2.2 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor PALP PF00291.20 EPS33141.1 - 3.2e-39 134.9 0.6 4.5e-39 134.4 0.4 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme zf-U1 PF06220.7 EPS33144.1 - 0.16 11.5 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 U1 zinc finger AMP-binding PF00501.23 EPS33148.1 - 7.7e-46 156.3 0.0 1.4e-45 155.4 0.0 1.3 1 1 0 1 1 1 1 AMP-binding enzyme Pyridoxal_deC PF00282.14 EPS33149.1 - 9.4e-79 264.5 0.0 1.4e-78 263.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain FWWh PF14922.1 EPS33149.1 - 0.12 11.9 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function Lactamase_B_2 PF12706.2 EPS33150.1 - 6.3e-19 68.2 0.3 8.4e-19 67.8 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EPS33150.1 - 3.8e-11 42.9 0.5 1.2e-10 41.3 0.1 2.0 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EPS33150.1 - 0.0021 17.7 0.4 0.012 15.2 0.2 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Sulfatase PF00884.18 EPS33153.1 - 4.8e-59 200.0 0.1 7.9e-59 199.3 0.1 1.3 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 EPS33153.1 - 1.1e-21 76.3 0.6 2.7e-21 75.1 0.4 1.7 1 0 0 1 1 1 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 EPS33153.1 - 4.7e-10 39.3 0.8 0.00013 21.3 0.2 2.3 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 EPS33153.1 - 0.0028 17.9 0.4 0.0091 16.2 0.2 1.8 1 1 1 2 2 2 1 C-terminal region of aryl-sulfatase DUF229 PF02995.12 EPS33153.1 - 0.021 13.2 0.0 0.026 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF1501 PF07394.7 EPS33153.1 - 0.082 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Peptidase_C16 PF01831.12 EPS33153.1 - 0.15 11.5 0.0 0.25 10.8 0.0 1.2 1 0 0 1 1 1 0 Peptidase C16 family EMP70 PF02990.11 EPS33154.1 - 7.8e-152 506.3 2.5 1.7e-151 505.2 1.7 1.5 1 1 0 1 1 1 1 Endomembrane protein 70 ubiquitin PF00240.18 EPS33155.1 - 3.1e-18 64.9 0.0 5.2e-18 64.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EPS33155.1 - 2.1e-09 36.9 0.0 7.3e-09 35.2 0.0 2.0 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.3 EPS33155.1 - 2.4e-08 33.5 0.0 3.7e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.5 EPS33155.1 - 0.00024 21.5 0.0 0.00044 20.7 0.0 1.5 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD Rad60-SLD_2 PF13881.1 EPS33155.1 - 0.00027 20.7 0.0 0.0005 19.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EPS33155.1 - 0.00036 20.6 0.0 0.00084 19.4 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_2 PF14560.1 EPS33155.1 - 0.029 14.6 0.1 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 Ubiquitin-like domain CPSF_A PF03178.10 EPS33156.1 - 1.9e-101 339.3 0.0 3.3e-99 332.0 0.0 3.1 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 EPS33156.1 - 5.8e-66 222.6 0.0 9.3e-66 221.9 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term BBS2_N PF14781.1 EPS33156.1 - 0.0062 16.1 0.0 0.98 9.0 0.0 3.3 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, N-terminal WD40 PF00400.27 EPS33156.1 - 0.28 11.1 1.0 0.85 9.6 0.1 2.4 2 0 0 2 2 2 0 WD domain, G-beta repeat Bul1_N PF04425.7 EPS33157.1 - 7.5e-09 34.6 1.1 2.7e-06 26.2 0.5 3.1 2 1 0 2 2 2 2 Bul1 N terminus Arrestin_N PF00339.24 EPS33157.1 - 4.1e-06 26.6 0.0 4.3e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.7 EPS33157.1 - 0.00026 20.2 0.0 0.00041 19.6 0.0 1.2 1 0 0 1 1 1 1 Bul1 C terminus Glyco_hydro_18 PF00704.23 EPS33160.1 - 2.5e-94 316.5 12.1 2.9e-94 316.3 8.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 BP28CT PF08146.7 EPS33161.1 - 3.3e-44 150.3 3.4 3.6e-44 150.1 0.2 2.9 3 0 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 EPS33161.1 - 1.3e-25 89.7 5.3 1.3e-25 89.7 3.7 6.2 6 1 1 7 7 7 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.1 EPS33161.1 - 1.6e-09 37.8 4.1 0.033 14.4 0.0 7.3 8 1 0 8 8 8 3 HEAT repeats HEAT PF02985.17 EPS33161.1 - 0.00087 19.1 2.4 2.3 8.5 0.0 6.1 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.1 EPS33161.1 - 0.18 12.3 16.8 8 7.0 0.1 7.6 6 1 1 7 7 7 0 HEAT-like repeat Glyoxal_oxid_N PF07250.6 EPS33161.1 - 0.25 10.3 0.0 0.47 9.4 0.0 1.4 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus NRDE-2 PF08424.5 EPS33162.1 - 3.2e-61 206.9 0.0 6.1e-60 202.7 0.0 2.3 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 EPS33162.1 - 2.2 9.1 9.9 26 5.8 0.0 5.6 5 1 1 6 6 6 0 Tetratricopeptide repeat NAD_binding_6 PF08030.7 EPS33163.1 - 1.2e-22 80.5 0.0 1.8e-22 79.8 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EPS33163.1 - 3.2e-22 78.4 0.0 7.2e-22 77.2 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EPS33163.1 - 2.1e-18 66.5 12.6 4.8e-18 65.4 8.7 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EPS33163.1 - 4.4e-05 23.5 0.0 0.00015 21.8 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EPS33163.1 - 0.036 14.6 0.0 2.7 8.6 0.0 2.5 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain Peptidase_C12 PF01088.16 EPS33165.1 - 3.4e-50 170.1 0.0 3.9e-50 170.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Pkinase PF00069.20 EPS33166.1 - 2.2e-16 59.8 0.0 2.9e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EPS33166.1 - 3e-07 29.6 0.0 6.6e-07 28.5 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EPS33166.1 - 5.2e-07 28.8 0.0 6.6e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EPS33166.1 - 2.5e-06 27.3 0.0 5.6e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EPS33166.1 - 4.5e-06 25.9 0.0 6.6e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 EPS33166.1 - 0.0037 16.8 0.0 0.0059 16.2 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EPS33166.1 - 0.0049 16.2 0.0 0.0076 15.6 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.6 EPS33166.1 - 0.0076 15.1 0.1 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 PIP49_C PF12260.3 EPS33166.1 - 0.017 14.5 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 APH PF01636.18 EPS33167.1 - 1.4e-10 41.3 0.5 1.4e-09 38.0 0.0 2.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family UDG PF03167.14 EPS33168.1 - 7.7e-18 64.4 0.0 1.2e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily SBDS PF01172.13 EPS33169.1 - 5.3e-24 83.8 0.1 6.7e-24 83.5 0.1 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Acyl-CoA_dh_M PF02770.14 EPS33169.1 - 0.021 14.3 0.4 0.12 11.9 0.0 2.1 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, middle domain RhoGEF PF00621.15 EPS33170.1 - 1e-15 58.0 0.2 4.7e-15 55.9 0.1 2.0 1 1 0 1 1 1 1 RhoGEF domain GRASP55_65 PF04495.9 EPS33171.1 - 1.7e-08 34.5 0.0 4e-08 33.3 0.0 1.5 2 0 0 2 2 2 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 EPS33171.1 - 8.5e-08 31.9 0.0 1.8e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 EPS33171.1 - 5.5e-06 26.4 0.0 1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) Ras PF00071.17 EPS33172.1 - 4.9e-49 165.8 0.0 6.1e-49 165.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPS33172.1 - 4.5e-16 59.4 0.0 8.8e-16 58.4 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EPS33172.1 - 7.3e-11 41.6 0.0 1e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 EPS33172.1 - 0.00011 22.3 0.1 0.00072 19.7 0.1 2.1 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 EPS33172.1 - 0.0025 16.9 0.0 0.0033 16.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.7 EPS33172.1 - 0.027 13.7 0.0 0.048 12.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.15 EPS33172.1 - 0.033 12.8 1.4 0.89 8.1 0.1 2.5 2 1 1 3 3 3 0 G-protein alpha subunit AAA_22 PF13401.1 EPS33172.1 - 0.043 13.9 0.2 0.15 12.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EPS33172.1 - 0.064 13.1 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EPS33172.1 - 0.11 12.0 0.1 0.22 11.1 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 SNF2_N PF00176.18 EPS33173.1 - 2.2e-71 240.0 0.2 3.1e-71 239.6 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPS33173.1 - 3.7e-13 49.1 0.0 1.2e-12 47.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 EPS33173.1 - 9.6e-08 31.5 3.8 1.8e-07 30.7 2.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPS33173.1 - 1.4e-07 31.4 6.9 2.7e-07 30.4 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EPS33173.1 - 1.8e-05 24.4 4.9 3.4e-05 23.5 3.4 1.5 1 0 0 1 1 1 1 Ring finger domain ResIII PF04851.10 EPS33173.1 - 3.3e-05 23.7 0.0 3.3e-05 23.7 0.0 2.7 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit zf-C3HC4_4 PF15227.1 EPS33173.1 - 4.6e-05 23.2 6.8 9.6e-05 22.1 4.7 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EPS33173.1 - 4.6e-05 22.9 6.7 9.1e-05 22.0 4.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EPS33173.1 - 7.9e-05 22.2 2.5 0.00019 21.0 1.7 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 EPS33173.1 - 0.00029 20.4 5.0 0.0007 19.2 3.5 1.7 1 0 0 1 1 1 1 zinc-RING finger domain DEAD PF00270.24 EPS33173.1 - 0.00044 19.7 0.0 0.001 18.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_4 PF14570.1 EPS33173.1 - 0.022 14.3 5.1 0.052 13.1 3.5 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DZR PF12773.2 EPS33173.1 - 0.53 10.1 3.5 2.9 7.7 2.4 2.1 2 0 0 2 2 2 0 Double zinc ribbon Prok-RING_4 PF14447.1 EPS33173.1 - 0.95 9.0 5.6 7.4 6.1 3.9 2.3 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 SCP2 PF02036.12 EPS33174.1 - 2e-26 92.2 0.6 2.4e-26 92.0 0.4 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 EPS33174.1 - 1.6e-06 28.0 0.1 2.1e-06 27.7 0.1 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal ABC_tran PF00005.22 EPS33175.1 - 1.5e-44 151.6 0.0 2.9e-27 95.6 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EPS33175.1 - 5.2e-38 131.0 20.6 7.9e-22 77.9 6.4 3.6 4 0 0 4 4 3 2 ABC transporter transmembrane region SMC_N PF02463.14 EPS33175.1 - 3.9e-13 49.1 5.6 1.8e-06 27.3 0.2 4.2 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EPS33175.1 - 4.6e-08 33.3 0.4 2.8 7.8 0.0 4.3 3 1 1 4 4 4 3 AAA domain AAA_23 PF13476.1 EPS33175.1 - 5.7e-07 30.0 0.4 0.00076 19.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EPS33175.1 - 2.2e-06 27.8 0.6 0.027 14.6 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EPS33175.1 - 4.8e-06 26.1 0.1 0.0047 16.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 EPS33175.1 - 1.6e-05 23.9 0.3 0.059 12.2 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.1 EPS33175.1 - 6.2e-05 23.0 0.9 0.053 13.5 0.2 2.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EPS33175.1 - 9.3e-05 21.8 8.5 0.002 17.6 0.1 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain DUF258 PF03193.11 EPS33175.1 - 0.00069 18.8 0.1 0.92 8.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_30 PF13604.1 EPS33175.1 - 0.00097 18.7 3.2 0.16 11.4 0.2 3.2 2 1 0 2 2 2 1 AAA domain Miro PF08477.8 EPS33175.1 - 0.0041 17.6 0.1 0.88 10.0 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_10 PF12846.2 EPS33175.1 - 0.0046 16.4 1.3 0.31 10.4 0.0 2.8 3 0 0 3 3 2 1 AAA-like domain NACHT PF05729.7 EPS33175.1 - 0.0051 16.4 2.4 2.5 7.7 0.0 3.2 2 1 1 3 3 3 2 NACHT domain AAA_17 PF13207.1 EPS33175.1 - 0.0067 17.2 0.0 0.74 10.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EPS33175.1 - 0.012 15.1 0.9 2.5 7.5 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.12 EPS33175.1 - 0.019 14.8 0.8 0.019 14.8 0.6 1.8 2 0 0 2 2 1 0 Domain of unknown function DUF87 AAA_33 PF13671.1 EPS33175.1 - 0.028 14.3 0.0 6.6 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EPS33175.1 - 0.036 13.5 2.2 0.68 9.3 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 EPS33175.1 - 0.061 13.6 0.0 6.5 7.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EPS33175.1 - 0.063 13.2 0.0 2.3 8.1 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.7 EPS33175.1 - 0.075 12.1 0.2 2.6 7.0 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin TrwB_AAD_bind PF10412.4 EPS33175.1 - 0.08 11.5 2.3 0.83 8.1 0.2 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Zot PF05707.7 EPS33175.1 - 0.084 12.3 0.7 0.38 10.1 0.0 2.4 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_19 PF13245.1 EPS33175.1 - 0.12 12.1 4.2 3.5 7.4 0.1 3.4 3 0 0 3 3 2 0 Part of AAA domain SbcCD_C PF13558.1 EPS33175.1 - 0.13 12.2 0.0 14 5.7 0.0 3.0 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.18 EPS33175.1 - 0.13 12.0 1.1 12 5.6 0.1 2.4 2 0 0 2 2 2 0 Dynamin family DEAD PF00270.24 EPS33175.1 - 0.17 11.4 1.6 19 4.7 0.9 3.3 2 1 0 2 2 2 0 DEAD/DEAH box helicase UPF0079 PF02367.12 EPS33175.1 - 0.18 11.4 1.0 0.49 10.0 0.2 2.1 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Cyclase PF04199.8 EPS33176.1 - 1.5e-16 60.5 0.0 2.5e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 Putative cyclase Pectate_lyase_3 PF12708.2 EPS33177.1 - 5e-88 295.0 25.3 3.8e-65 220.1 7.4 3.1 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EPS33177.1 - 5.4e-07 28.9 1.2 0.024 14.0 0.0 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Ran_BP1 PF00638.13 EPS33179.1 - 1.4e-09 38.0 0.0 3.3e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 RanBP1 domain Nucleoporin_FG PF13634.1 EPS33179.1 - 0.0014 18.8 24.2 0.0014 18.8 16.8 10.7 3 2 5 8 8 8 3 Nucleoporin FG repeat region Ribosomal_L31e PF01198.14 EPS33180.1 - 2e-37 126.6 0.9 2.7e-37 126.3 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L31e CN_hydrolase PF00795.17 EPS33181.1 - 1.3e-34 119.2 0.0 2.3e-34 118.3 0.0 1.4 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase ATG2_CAD PF13329.1 EPS33185.1 - 2.6e-50 170.0 0.2 1e-49 168.1 0.1 2.1 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 EPS33185.1 - 2.3e-26 91.7 0.0 5.6e-26 90.5 0.0 1.7 1 0 0 1 1 1 1 ATG C terminal domain Chorein_N PF12624.2 EPS33185.1 - 0.027 14.0 0.1 8.9 5.8 0.0 3.2 3 0 0 3 3 3 0 N-terminal region of Chorein, a TM vesicle-mediated sorter A_deaminase PF00962.17 EPS33186.1 - 1.2e-43 149.2 0.0 2.1e-43 148.5 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF3594 PF12165.3 EPS33187.1 - 0.096 12.3 0.0 0.35 10.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3594) Nucleos_tra2_C PF07662.8 EPS33188.1 - 4.4e-70 235.4 0.5 4.4e-70 235.4 0.3 2.4 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 EPS33188.1 - 1e-24 86.6 5.1 1e-24 86.6 3.5 2.6 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus UQ_con PF00179.21 EPS33189.1 - 1.2e-48 164.0 0.0 1.5e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EPS33189.1 - 0.0003 20.6 0.4 0.0005 19.9 0.3 1.6 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 EPS33189.1 - 0.00039 20.1 0.1 0.001 18.8 0.0 1.6 2 0 0 2 2 2 1 Prokaryotic E2 family B UEV PF05743.8 EPS33189.1 - 0.0017 18.0 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 UEV domain Pkinase PF00069.20 EPS33190.1 - 3.1e-62 210.0 0.0 4e-62 209.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS33190.1 - 2e-24 86.0 0.0 2.8e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPS33190.1 - 1.7e-07 30.4 0.0 2.4e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EPS33190.1 - 0.00053 19.7 0.0 0.33 10.6 0.0 2.6 3 0 0 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 EPS33190.1 - 0.02 13.9 0.0 0.046 12.7 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family F-box-like PF12937.2 EPS33191.1 - 2.6e-05 23.8 0.2 6e-05 22.6 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EPS33191.1 - 0.00086 18.9 1.0 0.0019 17.7 0.7 1.7 1 0 0 1 1 1 1 F-box domain MFS_1 PF07690.11 EPS33192.1 - 1.2e-44 152.4 24.5 6.6e-38 130.3 13.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EPS33192.1 - 3.5e-07 29.0 18.0 2.3e-05 22.9 5.9 2.6 3 0 0 3 3 3 2 MFS/sugar transport protein LacY_symp PF01306.14 EPS33192.1 - 0.00022 19.9 5.3 0.0057 15.2 0.1 3.0 3 0 0 3 3 3 2 LacY proton/sugar symporter DUF3784 PF12650.2 EPS33192.1 - 0.52 10.2 7.5 1.5 8.8 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3784) OATP PF03137.15 EPS33192.1 - 0.96 7.4 7.1 3.7 5.4 0.0 2.7 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family AMP-binding PF00501.23 EPS33193.1 - 2.3e-65 220.6 0.0 3.3e-65 220.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.15 EPS33193.1 - 2.5e-19 70.4 0.0 4.6e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 EPS33193.1 - 1.4e-07 31.6 0.0 6.3e-07 29.4 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family PP-binding PF00550.20 EPS33193.1 - 2.4e-07 30.9 0.0 5.8e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_5 PF12695.2 EPS33193.1 - 5.5e-05 22.9 0.0 0.00076 19.2 0.0 2.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family 2OG-FeII_Oxy PF03171.15 EPS33194.1 - 1.7e-07 31.4 0.0 3.1e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EPS33194.1 - 1.1e-06 29.1 0.0 1.8e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Haem_oxygenas_2 PF14518.1 EPS33195.1 - 1.6e-13 50.7 0.0 4.8e-13 49.1 0.0 1.9 1 0 0 1 1 1 1 Iron-containing redox enzyme FAD_binding_3 PF01494.14 EPS33196.1 - 8e-06 25.1 0.1 1.2e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain DHBP_synthase PF00926.14 EPS33198.1 - 1.5e-72 242.9 0.1 1.1e-71 240.0 0.1 1.9 1 1 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase NatB_MDM20 PF09797.4 EPS33198.1 - 0.09 11.4 0.0 0.14 10.8 0.0 1.3 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit TFIIE_beta PF02186.10 EPS33199.1 - 2.6e-06 27.3 0.1 1.5e-05 24.8 0.0 2.3 2 1 0 2 2 2 1 TFIIE beta subunit core domain TPR_MLP1_2 PF07926.7 EPS33200.1 - 6.1e-30 103.6 27.2 6.1e-30 103.6 18.9 16.4 7 5 9 17 17 17 8 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.3 EPS33200.1 - 0.0054 16.5 9.3 0.0054 16.5 6.5 22.7 15 7 8 24 24 24 10 TATA element modulatory factor 1 DNA binding Hexapep PF00132.19 EPS33201.1 - 3.1e-09 35.9 12.2 0.0065 15.9 0.5 4.4 2 2 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EPS33201.1 - 0.0013 18.2 2.4 0.0017 17.8 0.2 2.3 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase Acid_PPase PF12689.2 EPS33203.1 - 2.8e-69 232.1 0.0 3.3e-69 231.8 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.1 EPS33203.1 - 0.13 12.4 2.5 2 8.5 0.1 2.9 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase Sec63 PF02889.11 EPS33204.1 - 3.7e-48 164.3 0.0 5.8e-48 163.7 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 EPS33204.1 - 1e-26 93.4 0.1 2.1e-26 92.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EPS33204.1 - 7e-10 39.0 0.0 1.4e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EPS33204.1 - 3.1e-09 36.5 0.0 8.3e-09 35.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EPS33204.1 - 0.0003 19.6 0.1 0.0011 17.8 0.0 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain AAA_22 PF13401.1 EPS33204.1 - 0.01 15.9 0.1 0.032 14.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EPS33204.1 - 0.035 13.8 0.0 0.099 12.4 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain T2SE PF00437.15 EPS33204.1 - 0.058 12.2 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.1 EPS33204.1 - 0.059 12.9 0.0 0.12 11.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain UvrD-helicase PF00580.16 EPS33204.1 - 0.073 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Nuc_sug_transp PF04142.10 EPS33205.1 - 1.5e-59 201.0 3.3 2.6e-59 200.2 2.3 1.3 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 EPS33205.1 - 3.4e-09 36.0 4.1 8.5e-09 34.7 2.7 1.6 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EPS33205.1 - 0.0035 17.3 9.5 0.0035 17.3 6.6 3.1 2 1 0 2 2 2 1 EamA-like transporter family TPT PF03151.11 EPS33205.1 - 0.65 9.6 23.7 1.7 8.2 6.4 2.8 2 1 0 2 2 2 0 Triose-phosphate Transporter family EmrE PF13536.1 EPS33205.1 - 1.1 9.5 23.6 0.21 11.7 4.5 2.9 2 1 1 3 3 3 0 Multidrug resistance efflux transporter HORMA PF02301.13 EPS33208.1 - 3.6e-08 33.1 0.0 5.1e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 HORMA domain WD40 PF00400.27 EPS33209.1 - 1.5e-52 173.7 19.6 8.6e-09 34.9 0.0 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 EPS33209.1 - 2.7e-08 33.3 0.1 5.2e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EPS33209.1 - 3.3e-07 29.7 0.1 8.7e-07 28.4 0.0 1.7 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EPS33209.1 - 0.00059 18.0 9.2 0.28 9.2 0.2 5.0 3 2 2 5 5 5 4 Nucleoporin Nup120/160 MMR_HSR1 PF01926.18 EPS33210.1 - 2.4e-19 69.3 0.0 3.8e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EPS33210.1 - 6.8e-06 25.9 0.0 0.00022 21.0 0.0 2.1 2 0 0 2 2 2 1 Dynamin family FeoB_N PF02421.13 EPS33210.1 - 0.00032 20.0 0.0 0.00043 19.5 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EPS33210.1 - 0.00066 19.1 0.0 0.0087 15.5 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EPS33210.1 - 0.0022 17.2 0.0 0.0038 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EPS33210.1 - 0.0097 15.0 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.8 EPS33210.1 - 0.01 14.6 0.0 0.023 13.4 0.0 1.5 1 1 0 1 1 1 0 Interferon-inducible GTPase (IIGP) SRPRB PF09439.5 EPS33210.1 - 0.012 14.8 0.0 0.015 14.4 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.1 EPS33210.1 - 0.014 14.9 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EPS33210.1 - 0.018 15.3 0.1 0.028 14.6 0.1 1.5 1 1 0 1 1 1 0 ABC transporter Miro PF08477.8 EPS33210.1 - 0.14 12.7 0.0 0.18 12.2 0.0 1.4 1 1 0 1 1 1 0 Miro-like protein Clat_adaptor_s PF01217.15 EPS33211.1 - 5.7e-43 146.0 0.0 1.3e-42 144.8 0.0 1.5 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Ribosomal_L7Ae PF01248.21 EPS33212.1 - 5.6e-23 80.2 0.6 9.1e-23 79.5 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EPS33212.1 - 0.0018 18.1 0.0 0.0027 17.5 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 HEAT_EZ PF13513.1 EPS33213.1 - 0.00055 20.3 0.2 1.6 9.3 0.1 3.3 2 0 0 2 2 2 2 HEAT-like repeat CLASP_N PF12348.3 EPS33213.1 - 0.0016 17.8 1.5 0.046 13.0 0.1 3.2 3 1 0 3 3 3 1 CLASP N terminal Cnd1 PF12717.2 EPS33213.1 - 0.0023 17.8 0.1 0.006 16.4 0.1 1.6 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 TAN PF11640.3 EPS33213.1 - 0.005 16.5 0.0 0.038 13.7 0.0 2.3 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair HEAT PF02985.17 EPS33213.1 - 0.0098 15.8 1.1 4.3 7.6 0.2 3.9 3 0 0 3 3 3 1 HEAT repeat MMS19_N PF14500.1 EPS33213.1 - 0.015 14.5 0.2 0.054 12.7 0.1 1.8 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II APG6 PF04111.7 EPS33213.1 - 0.017 14.1 14.3 0.012 14.6 8.3 1.8 2 0 0 2 2 2 0 Autophagy protein Apg6 Suppressor_APC PF11414.3 EPS33213.1 - 0.12 12.1 7.0 1.4 8.7 4.8 2.3 1 1 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein IncA PF04156.9 EPS33213.1 - 0.19 11.3 11.6 0.035 13.6 4.6 2.2 2 0 0 2 2 2 0 IncA protein G-gamma PF00631.17 EPS33213.1 - 0.31 10.8 2.7 1.2 8.9 1.2 2.4 2 0 0 2 2 2 0 GGL domain HAUS6_N PF14661.1 EPS33213.1 - 0.33 10.2 7.8 1.1 8.6 5.4 1.8 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus ADIP PF11559.3 EPS33213.1 - 1.4 8.7 14.7 4 7.3 10.2 1.7 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF342 PF03961.8 EPS33213.1 - 2.8 6.2 5.2 4.9 5.4 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF972 PF06156.8 EPS33213.1 - 3.3 8.1 7.2 15 6.0 5.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) AAA_13 PF13166.1 EPS33213.1 - 6.8 5.0 9.3 13 4.0 6.5 1.4 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 EPS33214.1 - 1e-77 253.4 11.6 2.3e-12 46.2 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EPS33214.1 - 4e-09 35.1 0.2 0.0028 15.8 0.0 3.5 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EPS33214.1 - 0.013 14.2 0.1 2.7 6.6 0.0 3.4 2 2 2 4 4 4 0 Nup133 N terminal like Ribosomal_S17 PF00366.15 EPS33215.1 - 0.0006 19.7 2.5 0.0014 18.6 1.7 1.7 1 0 0 1 1 1 1 Ribosomal protein S17 FAD_binding_4 PF01565.18 EPS33218.1 - 9.7e-20 70.4 1.8 9.7e-20 70.4 1.2 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EPS33218.1 - 1.4e-10 40.9 0.6 2.7e-10 39.9 0.4 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EPS33218.1 - 0.094 11.8 0.0 0.26 10.4 0.0 1.7 2 0 0 2 2 2 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Glyco_transf_20 PF00982.16 EPS33219.1 - 9.7e-201 667.3 0.0 1.1e-200 667.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 EPS33219.1 - 0.018 14.5 0.3 0.04 13.3 0.1 1.7 2 0 0 2 2 2 0 Starch synthase catalytic domain Lactamase_B PF00753.22 EPS33220.1 - 1.8e-20 73.4 1.0 2.6e-20 72.8 0.7 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EPS33220.1 - 0.0005 19.6 0.1 0.00078 19.0 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EPS33220.1 - 0.015 14.9 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Aconitase PF00330.15 EPS33221.1 - 1.6e-176 587.3 0.0 2.9e-176 586.5 0.0 1.4 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EPS33221.1 - 2.6e-45 153.7 0.0 4.9e-45 152.8 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain zf-C2H2_jaz PF12171.3 EPS33222.1 - 8.2e-09 35.3 5.8 1.4e-08 34.6 4.0 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EPS33222.1 - 0.0016 18.5 0.2 0.0019 18.2 0.1 1.3 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EPS33222.1 - 0.0051 16.9 3.7 0.0089 16.2 2.6 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-LYAR PF08790.6 EPS33222.1 - 0.055 13.1 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger zf-U1 PF06220.7 EPS33222.1 - 0.069 12.7 1.3 0.13 11.8 0.9 1.4 1 0 0 1 1 1 0 U1 zinc finger zf-C2H2_4 PF13894.1 EPS33222.1 - 0.15 12.4 0.9 0.37 11.2 0.6 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EPS33222.1 - 0.16 12.2 2.1 0.32 11.3 1.4 1.6 1 0 0 1 1 1 0 C2H2-type zinc-finger domain Ribosomal_L2 PF00181.18 EPS33222.1 - 0.19 11.6 0.7 0.74 9.8 0.0 2.0 2 0 0 2 2 2 0 Ribosomal Proteins L2, RNA binding domain zf-H2C2_2 PF13465.1 EPS33222.1 - 1.1 9.6 3.4 1.6 9.1 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger double domain Mito_carr PF00153.22 EPS33223.1 - 2.4e-48 161.7 1.3 7.8e-20 70.3 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF2232 PF09991.4 EPS33223.1 - 0.023 13.6 0.0 0.038 12.9 0.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF4043 PF13252.1 EPS33223.1 - 0.17 10.8 0.0 11 4.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4043) Rad54_N PF08658.5 EPS33224.1 - 1.6e-62 210.8 2.4 4.1e-61 206.1 1.8 2.2 2 0 0 2 2 2 1 Rad54 N terminal SNF2_N PF00176.18 EPS33224.1 - 5.7e-62 209.1 0.0 8.1e-62 208.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPS33224.1 - 1.3e-12 47.3 0.0 3.8e-12 45.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EPS33224.1 - 1.4e-05 24.0 0.0 3.8e-05 22.6 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 EPS33224.1 - 0.004 17.0 0.0 0.014 15.2 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EPS33224.1 - 0.16 12.1 0.0 2.7 8.1 0.0 2.7 2 1 0 2 2 2 0 AAA domain Vac14_Fig4_bd PF11916.3 EPS33225.1 - 9.8e-84 279.0 7.7 9.8e-84 279.0 5.3 2.0 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 EPS33225.1 - 4e-45 152.1 0.0 8.3e-43 144.7 0.0 3.6 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EPS33225.1 - 2e-08 33.6 1.7 0.0004 20.2 0.0 5.6 6 0 0 6 6 6 1 HEAT repeat HEAT_EZ PF13513.1 EPS33225.1 - 7.1e-08 32.7 7.4 0.00098 19.5 0.0 5.4 5 1 1 6 6 6 2 HEAT-like repeat HEAT_2 PF13646.1 EPS33225.1 - 2.7e-07 30.7 1.6 0.006 16.8 0.0 4.9 5 1 1 6 6 6 2 HEAT repeats Ipi1_N PF12333.3 EPS33225.1 - 0.029 14.3 0.0 3.1 7.8 0.0 3.3 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation Arm PF00514.18 EPS33225.1 - 0.032 14.0 0.0 10 6.1 0.0 4.1 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat AIM24 PF01987.12 EPS33227.1 - 1.7e-47 161.6 0.0 2.3e-47 161.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DUF4402 PF14352.1 EPS33227.1 - 0.0058 17.0 0.2 0.043 14.2 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4402) ABC_tran PF00005.22 EPS33228.1 - 4.7e-34 117.6 0.0 9.3e-34 116.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EPS33228.1 - 5.9e-34 117.7 12.7 8.4e-34 117.2 8.8 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 EPS33228.1 - 2.5e-07 30.9 0.1 0.0049 16.8 0.0 2.5 2 1 1 3 3 2 2 AAA domain AAA_16 PF13191.1 EPS33228.1 - 6.9e-06 26.1 0.1 5.1e-05 23.3 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.14 EPS33228.1 - 4.1e-05 22.9 0.0 0.029 13.5 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EPS33228.1 - 0.00014 22.6 0.0 0.00035 21.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EPS33228.1 - 0.0005 20.2 0.1 0.0031 17.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EPS33228.1 - 0.00054 19.8 0.0 0.032 14.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF2847 PF11009.3 EPS33228.1 - 0.0015 18.1 0.0 0.0032 17.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2847) AAA_29 PF13555.1 EPS33228.1 - 0.0028 17.1 0.0 0.0089 15.5 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.2 EPS33228.1 - 0.0034 16.8 0.4 0.02 14.3 0.2 2.1 1 1 0 1 1 1 1 AAA-like domain ABC_ATPase PF09818.4 EPS33228.1 - 0.0045 15.6 0.0 0.049 12.2 0.0 2.0 2 0 0 2 2 2 1 Predicted ATPase of the ABC class DUF258 PF03193.11 EPS33228.1 - 0.0099 15.0 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EPS33228.1 - 0.012 15.0 0.0 0.036 13.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EPS33228.1 - 0.016 15.5 0.3 0.051 13.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EPS33228.1 - 0.032 14.2 0.1 0.21 11.5 0.1 2.3 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EPS33228.1 - 0.032 14.4 0.0 0.21 11.7 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EPS33228.1 - 0.041 14.1 0.0 0.12 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 EPS33228.1 - 0.048 13.5 1.4 0.37 10.7 0.2 2.8 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ATP-synt_ab PF00006.20 EPS33228.1 - 0.05 13.0 0.0 0.095 12.1 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.9 EPS33228.1 - 0.066 12.9 0.0 0.24 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EPS33228.1 - 0.073 12.9 0.1 0.47 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.10 EPS33228.1 - 0.12 11.0 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein MFS_1 PF07690.11 EPS33230.1 - 7.2e-31 107.1 59.2 2.3e-25 89.0 23.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS33230.1 - 3.1e-05 22.7 36.0 0.0031 16.1 1.8 3.4 2 2 1 3 3 3 2 Sugar (and other) transporter APOC4 PF15119.1 EPS33230.1 - 0.19 11.7 0.0 0.46 10.4 0.0 1.6 1 0 0 1 1 1 0 Apolipoprotein C4 Kinesin PF00225.18 EPS33231.1 - 3.5e-81 272.5 0.7 3.5e-81 272.5 0.5 2.0 2 0 0 2 2 2 1 Kinesin motor domain HHH PF00633.18 EPS33231.1 - 1.3e-05 24.6 0.4 0.021 14.5 0.0 3.6 3 0 0 3 3 3 2 Helix-hairpin-helix motif HHH_5 PF14520.1 EPS33231.1 - 0.0036 17.4 0.0 0.013 15.6 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_3 PF12836.2 EPS33231.1 - 0.075 12.9 0.2 1.3 9.0 0.0 2.9 3 0 0 3 3 3 0 Helix-hairpin-helix motif MerR-DNA-bind PF09278.6 EPS33231.1 - 0.22 11.9 5.5 0.77 10.1 2.3 2.7 2 0 0 2 2 2 0 MerR, DNA binding Sec23_trunk PF04811.10 EPS33232.1 - 6.8e-71 238.4 0.0 1.2e-70 237.7 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EPS33232.1 - 1e-24 85.8 0.1 1.2e-23 82.5 0.0 2.5 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 EPS33232.1 - 7e-18 63.9 5.3 1.2e-17 63.1 3.6 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 EPS33232.1 - 1.1e-17 64.3 0.0 2.7e-17 63.0 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 EPS33232.1 - 2.3e-10 40.0 0.0 4.2e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Paf1 PF03985.8 EPS33233.1 - 5.3 5.6 8.0 5.8 5.5 5.6 1.0 1 0 0 1 1 1 0 Paf1 Pkinase PF00069.20 EPS33234.1 - 2.5e-74 249.7 0.0 3e-74 249.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS33234.1 - 4.7e-32 111.0 0.0 6.1e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPS33234.1 - 0.00058 18.9 0.0 0.0017 17.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EPS33234.1 - 0.001 18.2 0.1 0.0015 17.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPS33234.1 - 0.012 15.3 0.2 0.029 14.1 0.2 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EPS33234.1 - 0.069 11.9 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 HEM4 PF02602.10 EPS33235.1 - 7.4e-31 107.1 0.0 7.6e-15 54.7 0.0 3.2 2 1 1 3 3 3 3 Uroporphyrinogen-III synthase HemD HTH_22 PF13309.1 EPS33235.1 - 0.14 11.8 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 HTH domain NAD_binding_10 PF13460.1 EPS33236.1 - 9.2e-20 71.4 0.0 1.3e-19 70.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EPS33236.1 - 2.4e-17 63.0 0.0 2.8e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EPS33236.1 - 3.7e-15 56.0 0.0 5.9e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPS33236.1 - 3.7e-12 45.5 0.1 6.2e-12 44.7 0.1 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EPS33236.1 - 7e-10 38.2 0.0 2e-08 33.5 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EPS33236.1 - 7.5e-06 25.0 0.6 0.0025 16.7 0.2 3.0 1 1 1 2 2 2 1 Male sterility protein adh_short PF00106.20 EPS33236.1 - 9e-06 25.7 0.0 0.00014 21.8 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EPS33236.1 - 0.0014 17.5 0.0 0.0021 17.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EPS33236.1 - 0.0039 16.8 0.0 0.86 9.2 0.0 2.5 1 1 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 EPS33236.1 - 0.0061 15.5 0.0 0.0096 14.9 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase DDE_Tnp_1_3 PF13612.1 EPS33236.1 - 0.02 14.6 0.0 0.087 12.5 0.0 1.9 2 0 0 2 2 2 0 Transposase DDE domain FMO-like PF00743.14 EPS33237.1 - 1.4e-39 135.6 0.0 8.5e-30 103.4 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EPS33237.1 - 9.8e-19 68.2 0.0 2e-18 67.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EPS33237.1 - 4.8e-10 38.8 0.0 6.3e-09 35.1 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EPS33237.1 - 9.1e-09 35.4 0.0 4e-08 33.3 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPS33237.1 - 6.7e-06 25.9 0.0 5.4e-05 23.0 0.0 2.6 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EPS33237.1 - 0.0018 18.2 0.0 0.0045 16.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 EPS33237.1 - 0.03 14.5 0.0 4 7.7 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding DAO PF01266.19 EPS33237.1 - 0.11 11.4 0.0 6.2 5.6 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase HIT PF01230.18 EPS33238.1 - 1.2e-22 80.2 0.0 1.9e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EPS33238.1 - 2.1e-12 47.2 0.0 3.7e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EPS33238.1 - 0.0007 19.2 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CRAL_TRIO PF00650.15 EPS33239.1 - 3.1e-46 156.7 0.0 4.9e-46 156.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EPS33239.1 - 2.8e-16 59.3 1.4 5.2e-16 58.5 0.1 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EPS33239.1 - 1.1e-12 48.1 0.0 2.2e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DASH_Dam1 PF08653.5 EPS33240.1 - 4e-29 100.1 1.8 5.4e-29 99.7 1.3 1.2 1 0 0 1 1 1 1 DASH complex subunit Dam1 UCH PF00443.24 EPS33242.1 - 2.2e-53 181.0 3.1 3.5e-53 180.4 2.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPS33242.1 - 3.8e-25 88.9 0.4 5.2e-25 88.4 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EPS33242.1 - 0.00017 21.6 1.6 0.00017 21.6 1.1 3.4 3 1 1 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein PHD_3 PF13922.1 EPS33242.1 - 0.085 13.1 6.4 0.94 9.7 0.1 3.3 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx Ribosomal_S27e PF01667.12 EPS33242.1 - 5.5 6.6 13.4 0.63 9.6 1.3 3.7 4 0 0 4 4 4 0 Ribosomal protein S27 Ribosomal_S14 PF00253.16 EPS33243.1 - 7e-18 63.7 6.0 7.6e-18 63.6 4.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.1 EPS33243.1 - 0.15 11.8 0.3 0.2 11.4 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) Prim_Zn_Ribbon PF08273.7 EPS33243.1 - 0.74 9.9 4.2 11 6.2 0.3 2.1 1 1 1 2 2 2 0 Zinc-binding domain of primase-helicase Toxin_17 PF08086.6 EPS33243.1 - 0.9 9.6 5.0 0.48 10.5 0.3 2.0 1 1 1 2 2 2 0 Ergtoxin family DUF2300 PF10062.4 EPS33244.1 - 0.02 14.6 0.0 1.5 8.6 0.0 2.1 2 0 0 2 2 2 0 Predicted secreted protein (DUF2300) Ytp1 PF10355.4 EPS33245.1 - 5.4e-114 379.9 9.6 1e-113 379.0 6.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EPS33245.1 - 8.4e-37 124.9 12.7 1.4e-34 117.7 3.8 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF2427) DLH PF01738.13 EPS33247.1 - 1e-33 116.4 0.1 1.2e-33 116.2 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EPS33247.1 - 1.9e-07 30.9 0.0 2.4e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPS33247.1 - 6.4e-05 22.9 0.0 0.00099 19.0 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPS33247.1 - 0.0034 16.9 0.0 0.0087 15.6 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Rhomboid PF01694.17 EPS33248.1 - 3.7e-13 49.7 8.4 3.7e-13 49.7 5.8 1.7 2 0 0 2 2 2 1 Rhomboid family Gaa1 PF04114.9 EPS33249.1 - 3.8e-95 319.5 13.3 1.5e-94 317.5 9.2 1.9 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component PCI PF01399.22 EPS33250.1 - 3.4e-10 40.1 0.0 6.8e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 PCI domain Methyltransf_23 PF13489.1 EPS33251.1 - 1.6e-16 60.4 1.5 3.4e-16 59.3 1.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPS33251.1 - 3.7e-13 49.3 0.0 4.6e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPS33251.1 - 4.8e-12 46.1 0.0 1e-11 45.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPS33251.1 - 1.4e-11 44.7 0.0 2.8e-11 43.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS33251.1 - 1.7e-11 44.6 0.0 2.6e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPS33251.1 - 5.4e-11 42.0 0.0 1.9e-10 40.2 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EPS33251.1 - 5.1e-10 39.6 0.0 1.1e-09 38.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPS33251.1 - 3.8e-05 23.6 0.0 8.6e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPS33251.1 - 0.00012 21.4 0.0 0.00026 20.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.15 EPS33251.1 - 0.01 14.8 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase tRNA_U5-meth_tr PF05958.6 EPS33251.1 - 0.024 13.3 0.0 0.036 12.7 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.5 EPS33251.1 - 0.027 14.0 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Pox_MCEL PF03291.11 EPS33251.1 - 0.066 12.0 0.0 0.13 11.1 0.0 1.4 1 1 0 1 1 1 0 mRNA capping enzyme Methyltrans_SAM PF10672.4 EPS33251.1 - 0.14 10.9 0.0 0.32 9.8 0.0 1.6 1 1 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase BAF1_ABF1 PF04684.8 EPS33251.1 - 0.31 9.8 9.9 0.42 9.3 6.8 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Epiglycanin_C PF14654.1 EPS33251.1 - 2.5 8.1 9.8 4.7 7.2 6.8 1.5 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region Romo1 PF10247.4 EPS33252.1 - 0.065 13.4 0.5 0.51 10.5 0.0 2.2 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Peptidase_M20 PF01546.23 EPS33253.1 - 5.7e-23 81.4 0.2 7.7e-23 80.9 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EPS33253.1 - 0.00017 21.3 0.0 0.00029 20.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EPS33253.1 - 0.014 15.1 0.0 0.034 13.8 0.0 1.7 2 0 0 2 2 2 0 Peptidase family M28 T2SM_b PF10741.4 EPS33253.1 - 0.2 11.2 0.8 0.38 10.3 0.1 1.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M subtype b S10_plectin PF03501.10 EPS33254.1 - 4.6e-42 141.7 0.2 5.8e-42 141.4 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Telomere_Sde2 PF13019.1 EPS33255.1 - 1.4e-63 213.3 0.2 1.4e-63 213.3 0.1 1.5 2 0 0 2 2 2 1 Telomere stability and silencing Rotamase_2 PF13145.1 EPS33255.1 - 0.045 14.3 1.2 0.045 14.3 0.8 1.7 2 0 0 2 2 2 0 PPIC-type PPIASE domain DUF2407 PF10302.4 EPS33255.1 - 0.61 10.3 6.6 57 3.9 4.6 2.9 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Sox_N PF12444.3 EPS33255.1 - 1.9 9.6 14.5 0.42 11.7 3.5 3.0 2 1 0 2 2 2 0 Sox developmental protein N terminal MMR_HSR1 PF01926.18 EPS33256.1 - 9.1e-07 28.8 0.0 2.2e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATPase-cat_bd PF12156.3 EPS33256.1 - 0.0028 18.1 0.0 0.0068 16.9 0.0 1.6 1 0 0 1 1 1 1 Putative metal-binding domain of cation transport ATPase Dynamin_N PF00350.18 EPS33256.1 - 0.013 15.3 0.2 0.81 9.4 0.1 2.6 1 1 1 2 2 2 0 Dynamin family Miro PF08477.8 EPS33256.1 - 0.034 14.6 0.0 0.11 12.9 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein DUF258 PF03193.11 EPS33256.1 - 0.065 12.4 0.0 0.8 8.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF258 NEMO PF11577.3 EPS33256.1 - 0.15 11.8 3.7 0.085 12.6 0.9 1.8 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO Nod_GRP PF07806.6 EPS33256.1 - 0.38 10.4 2.5 0.86 9.2 1.7 1.5 1 0 0 1 1 1 0 Nodule-specific GRP repeat tRNA-synt_1 PF00133.17 EPS33257.1 - 1.2e-35 122.5 0.0 1.1e-24 86.4 0.0 3.4 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EPS33257.1 - 4.2e-17 61.8 0.0 2.7e-11 42.7 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EPS33257.1 - 9.7e-16 57.8 0.1 2.6e-15 56.4 0.1 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EPS33257.1 - 2.7e-07 30.0 0.0 5.4e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 EPS33257.1 - 0.0046 15.6 0.0 0.23 10.0 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class I (K) L51_S25_CI-B8 PF05047.11 EPS33258.1 - 2.1e-16 59.3 0.0 3.1e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain ATP-synt_B PF00430.13 EPS33258.1 - 5.5 6.7 9.6 18 5.1 6.6 1.8 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) DUF1751 PF08551.5 EPS33259.1 - 3.2e-29 101.1 1.8 7.2e-29 100.0 1.3 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 EPS33259.1 - 3.5e-05 23.8 7.6 6.9e-05 22.9 5.3 1.5 1 1 0 1 1 1 1 Rhomboid family LisH PF08513.6 EPS33261.1 - 1.1e-06 28.1 0.3 2.6e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 LisH WD40 PF00400.27 EPS33261.1 - 7.4e-06 25.6 8.7 0.025 14.4 0.0 6.2 7 0 0 7 7 7 2 WD domain, G-beta repeat eIF2A PF08662.6 EPS33261.1 - 0.056 13.1 0.0 0.41 10.3 0.0 2.3 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A TSKS PF15358.1 EPS33262.1 - 0.00064 18.0 0.4 0.00087 17.5 0.3 1.2 1 0 0 1 1 1 1 Testis-specific serine kinase substrate IncA PF04156.9 EPS33262.1 - 0.0016 18.0 2.0 0.004 16.7 1.4 1.7 1 0 0 1 1 1 1 IncA protein TPR_MLP1_2 PF07926.7 EPS33262.1 - 0.05 13.3 1.7 0.18 11.5 1.2 2.0 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein bZIP_1 PF00170.16 EPS33262.1 - 0.42 10.5 12.4 0.075 13.0 2.0 3.0 2 1 0 2 2 2 0 bZIP transcription factor HR1 PF02185.11 EPS33262.1 - 0.63 9.8 4.0 1.8 8.3 0.3 2.6 3 0 0 3 3 3 0 Hr1 repeat Chorismate_bind PF00425.13 EPS33263.1 - 9.8e-88 293.7 0.0 1.5e-87 293.2 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 EPS33263.1 - 1.1e-28 100.0 0.0 1.6e-25 89.7 0.0 2.9 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region Hexokinase_2 PF03727.11 EPS33264.1 - 3.2e-25 88.7 0.0 3.4e-19 68.9 0.0 2.2 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 EPS33264.1 - 4.6e-22 78.3 0.0 1.6e-21 76.5 0.0 1.8 1 1 0 1 1 1 1 Hexokinase BolA PF01722.13 EPS33265.1 - 1.1e-21 76.5 0.0 1.3e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein NIF3 PF01784.13 EPS33266.1 - 1e-55 188.9 0.0 1.3e-55 188.6 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) GreA_GreB_N PF03449.10 EPS33266.1 - 0.071 13.1 0.2 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Transcription elongation factor, N-terminal ENTH PF01417.15 EPS33267.1 - 1.5e-47 160.5 0.0 2.4e-47 159.8 0.0 1.4 1 0 0 1 1 1 1 ENTH domain UIM PF02809.15 EPS33267.1 - 0.00016 20.9 2.8 0.00026 20.2 0.7 2.3 2 0 0 2 2 2 1 Ubiquitin interaction motif ANTH PF07651.11 EPS33267.1 - 0.00045 19.0 0.0 0.00072 18.3 0.0 1.3 1 0 0 1 1 1 1 ANTH domain DUF4264 PF14084.1 EPS33267.1 - 0.02 14.2 0.0 0.054 12.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4264) Redoxin PF08534.5 EPS33268.1 - 5.8e-27 94.0 0.0 6.8e-27 93.8 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EPS33268.1 - 2.5e-08 33.6 0.0 3.1e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family HSF_DNA-bind PF00447.12 EPS33270.1 - 2.3e-34 117.6 0.2 5e-34 116.5 0.2 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 EPS33270.1 - 1.2e-21 76.8 0.0 2.2e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Clusterin PF01093.12 EPS33270.1 - 0.0022 16.8 2.0 0.0036 16.1 1.4 1.2 1 0 0 1 1 1 1 Clusterin IncA PF04156.9 EPS33270.1 - 0.058 12.9 3.6 0.09 12.3 2.5 1.2 1 0 0 1 1 1 0 IncA protein DUF1582 PF07621.6 EPS33270.1 - 0.15 12.1 1.2 3.6 7.7 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1582) SlyX PF04102.7 EPS33270.1 - 1.1 9.6 10.5 0.16 12.3 4.0 2.1 2 0 0 2 2 2 0 SlyX W2 PF02020.13 EPS33271.1 - 5.6e-17 61.4 8.5 5.6e-17 61.4 5.9 3.0 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 EPS33271.1 - 1.1e-11 43.6 11.6 0.0016 17.8 1.3 4.5 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EPS33271.1 - 3.4e-11 42.5 7.3 1.1e-05 24.9 0.7 3.5 2 1 1 3 3 3 3 Hexapeptide repeat of succinyl-transferase NTP_transferase PF00483.18 EPS33271.1 - 1.5e-07 31.0 0.0 3.3e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EPS33271.1 - 0.0027 17.7 0.0 0.0056 16.7 0.0 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain UPF0181 PF03701.9 EPS33271.1 - 0.007 15.6 0.0 0.016 14.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0181) IBR PF01485.16 EPS33272.1 - 2e-23 82.0 42.5 2.2e-12 46.6 3.1 4.5 3 1 1 4 4 4 3 IBR domain zf-RING_2 PF13639.1 EPS33272.1 - 1.9e-08 34.0 36.2 5e-06 26.2 2.6 3.6 3 0 0 3 3 3 3 Ring finger domain zf-C3HC4 PF00097.20 EPS33272.1 - 2.3e-07 30.3 35.2 7.6e-05 22.2 2.7 4.5 3 1 1 4 4 4 3 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPS33272.1 - 1.1e-05 25.2 7.0 1.1e-05 25.2 4.9 4.6 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) UN_NPL4 PF11543.3 EPS33272.1 - 0.0076 16.5 0.0 0.015 15.5 0.0 1.4 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 zf-RING_5 PF14634.1 EPS33272.1 - 0.013 15.1 8.2 0.013 15.1 5.7 3.9 2 1 1 3 3 3 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 EPS33272.1 - 3.8 7.3 20.0 0.12 12.1 1.0 3.7 3 0 0 3 3 3 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EPS33272.1 - 7 6.6 33.9 1.2 9.0 3.1 4.6 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING Mito_carr PF00153.22 EPS33273.1 - 3.4e-68 225.3 6.7 6.9e-25 86.5 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein AAA PF00004.24 EPS33274.1 - 1.2e-37 129.0 0.1 2.6e-37 127.9 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EPS33274.1 - 1.1e-06 28.3 0.0 1.2e-05 25.0 0.0 2.7 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 EPS33274.1 - 7.2e-06 26.1 0.2 6e-05 23.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EPS33274.1 - 6.8e-05 22.0 0.0 0.00012 21.2 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EPS33274.1 - 0.00015 21.7 0.0 0.00028 20.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EPS33274.1 - 0.00051 19.7 0.1 0.0031 17.2 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EPS33274.1 - 0.0017 17.8 0.0 0.0032 16.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EPS33274.1 - 0.0019 16.9 0.0 0.0031 16.2 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 EPS33274.1 - 0.0035 16.5 0.1 0.008 15.3 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EPS33274.1 - 0.0056 16.5 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPS33274.1 - 0.0069 16.1 0.1 0.026 14.2 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_16 PF13191.1 EPS33274.1 - 0.012 15.5 0.2 0.012 15.5 0.1 2.8 3 1 0 3 3 3 0 AAA ATPase domain AAA_11 PF13086.1 EPS33274.1 - 0.013 15.0 0.0 0.063 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 EPS33274.1 - 0.019 13.8 0.0 0.032 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 EPS33274.1 - 0.019 14.5 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EPS33274.1 - 0.021 14.2 0.2 0.14 11.5 0.1 2.2 1 1 0 2 2 2 0 AAA domain ResIII PF04851.10 EPS33274.1 - 0.043 13.6 0.0 0.65 9.7 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_28 PF13521.1 EPS33274.1 - 0.043 13.7 0.0 0.16 11.8 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EPS33274.1 - 0.049 14.4 0.0 0.11 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EPS33274.1 - 0.085 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EPS33274.1 - 0.099 12.2 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Guanylate_kin PF00625.16 EPS33274.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Guanylate kinase Sigma54_activat PF00158.21 EPS33274.1 - 0.15 11.5 0.0 0.33 10.4 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.11 EPS33274.1 - 0.16 11.1 0.0 0.32 10.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein 2TM PF13239.1 EPS33275.1 - 1.7 8.7 7.4 0.5 10.4 0.1 2.8 3 0 0 3 3 3 0 2TM domain Abhydrolase_5 PF12695.2 EPS33276.1 - 1.6e-05 24.6 0.0 2.4e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 EPS33276.1 - 0.00028 20.2 0.1 0.00061 19.0 0.0 1.6 1 1 0 1 1 1 1 Esterase PHB depolymerase Esterase PF00756.15 EPS33276.1 - 0.004 16.6 0.0 0.005 16.2 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 EPS33276.1 - 0.0071 15.5 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family COG6 PF06419.6 EPS33279.1 - 4.9e-239 794.5 0.0 5.4e-239 794.4 0.0 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 DUF948 PF06103.6 EPS33279.1 - 0.042 13.7 0.3 0.13 12.1 0.2 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Tnp_DNA_bind PF14706.1 EPS33279.1 - 0.043 13.5 0.0 0.12 12.0 0.0 1.8 1 0 0 1 1 1 0 Transposase DNA-binding COG2 PF06148.6 EPS33279.1 - 1.6 8.6 6.4 0.3 10.9 0.4 2.8 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF972 PF06156.8 EPS33279.1 - 2.2 8.6 6.7 6.1 7.2 0.4 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF972) DUF342 PF03961.8 EPS33280.1 - 0.026 12.9 1.5 0.026 12.9 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Spc7 PF08317.6 EPS33280.1 - 0.041 12.5 1.6 0.077 11.6 1.1 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Syntaxin_2 PF14523.1 EPS33280.1 - 0.11 12.5 1.7 4.4 7.4 0.0 2.6 2 1 1 3 3 3 0 Syntaxin-like protein Cob_adeno_trans PF01923.13 EPS33280.1 - 0.28 10.9 6.1 0.94 9.2 0.2 3.1 3 1 1 4 4 4 0 Cobalamin adenosyltransferase AAA_13 PF13166.1 EPS33280.1 - 0.5 8.7 5.8 0.67 8.3 4.0 1.3 1 0 0 1 1 1 0 AAA domain EcoR124_C PF12008.3 EPS33280.1 - 0.85 8.7 5.8 8.2 5.5 0.0 2.6 3 0 0 3 3 3 0 Type I restriction and modification enzyme - subunit R C terminal HSP9_HSP12 PF04119.7 EPS33281.1 - 4.9e-29 100.1 8.1 9e-29 99.3 4.8 1.8 2 0 0 2 2 2 1 Heat shock protein 9/12 MRP-L28 PF09812.4 EPS33281.1 - 0.064 13.0 0.2 0.078 12.7 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 YtxH PF12732.2 EPS33281.1 - 0.48 10.8 2.4 1.3 9.4 1.6 1.8 1 1 0 1 1 1 0 YtxH-like protein NYN PF01936.13 EPS33282.1 - 0.00049 20.4 0.0 0.002 18.3 0.0 2.0 1 1 0 1 1 1 1 NYN domain Mog1 PF04603.7 EPS33283.1 - 1e-13 51.4 0.0 7.8e-10 38.8 0.0 3.0 3 0 0 3 3 3 2 Ran-interacting Mog1 protein CPSase_L_D2 PF02786.12 EPS33283.1 - 0.099 11.9 0.1 0.15 11.3 0.1 1.2 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain SprT-like PF10263.4 EPS33284.1 - 1.7e-49 167.4 2.3 2.6e-49 166.8 1.6 1.3 1 0 0 1 1 1 1 SprT-like family Peptidase_MA_2 PF13485.1 EPS33284.1 - 0.025 14.6 0.2 0.074 13.1 0.1 1.8 1 0 0 1 1 1 0 Peptidase MA superfamily GAS PF13851.1 EPS33284.1 - 0.07 12.3 2.0 0.13 11.4 0.5 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF2072 PF09845.4 EPS33284.1 - 0.086 12.7 0.1 0.36 10.7 0.1 2.1 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) DUF4379 PF14311.1 EPS33284.1 - 0.1 12.3 4.3 0.4 10.5 3.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4379) Zn-ribbon_8 PF09723.5 EPS33284.1 - 0.14 12.1 0.8 0.32 10.9 0.6 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Glucan_synthase PF02364.10 EPS33286.1 - 0 1477.9 0.0 0 1477.4 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EPS33286.1 - 1.7e-39 134.3 0.7 3.8e-39 133.2 0.5 1.6 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Aminotran_1_2 PF00155.16 EPS33287.1 - 2.8e-35 121.9 0.0 3.5e-35 121.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EPS33287.1 - 0.024 12.9 0.0 0.047 11.9 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Glyco_hydro_17 PF00332.13 EPS33288.1 - 0.00079 18.5 0.1 0.0018 17.3 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 Apt1 PF10351.4 EPS33289.1 - 0.05 12.4 3.9 0.085 11.7 2.7 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain WD40 PF00400.27 EPS33290.1 - 2e-14 52.8 1.3 0.002 17.9 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF3275 PF11679.3 EPS33290.1 - 6.2 6.3 7.9 11 5.5 1.7 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3275) Fungal_trans PF04082.13 EPS33291.1 - 1e-06 27.8 0.8 2.3e-06 26.7 0.5 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS33291.1 - 7.8e-06 25.6 8.5 7.8e-06 25.6 5.9 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RasGAP PF00616.14 EPS33292.1 - 1.1e-44 152.4 0.0 2.4e-44 151.3 0.0 1.7 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 EPS33292.1 - 5.4e-08 32.5 0.1 1.4e-07 31.2 0.1 1.7 1 0 0 1 1 1 1 C2 domain APG9 PF04109.11 EPS33293.1 - 5.1e-168 558.7 4.2 6.4e-168 558.4 2.9 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 Glyco_hydro_47 PF01532.15 EPS33294.1 - 2.3e-180 600.0 0.0 2.8e-180 599.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 4HB_MCP_1 PF12729.2 EPS33294.1 - 0.035 13.4 0.0 0.088 12.1 0.0 1.6 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction DUF2013 PF09431.5 EPS33295.1 - 6.6e-51 171.7 2.6 6.6e-51 171.7 1.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) COQ9 PF08511.6 EPS33296.1 - 1.5e-20 72.4 0.0 2.4e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 COQ9 RRM_1 PF00076.17 EPS33297.1 - 4.9e-55 183.0 0.0 2.9e-17 62.0 0.0 3.5 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS33297.1 - 2.1e-43 146.1 0.0 4.3e-15 55.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS33297.1 - 4.6e-24 84.0 0.0 2.9e-07 30.2 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EPS33297.1 - 0.0002 21.1 0.0 1.2 9.0 0.0 3.4 3 0 0 3 3 3 2 RNA binding motif Limkain-b1 PF11608.3 EPS33297.1 - 0.00083 19.0 0.1 1.5 8.5 0.0 4.2 3 2 0 3 3 3 1 Limkain b1 ATP-grasp_2 PF08442.5 EPS33297.1 - 0.049 13.0 0.0 0.35 10.2 0.0 2.3 3 0 0 3 3 3 0 ATP-grasp domain Glypican PF01153.14 EPS33300.1 - 1.1 7.7 5.2 1.1 7.7 3.6 1.2 1 0 0 1 1 1 0 Glypican PH PF00169.24 EPS33301.1 - 7.9e-12 45.3 0.1 2e-11 44.0 0.0 1.7 1 0 0 1 1 1 1 PH domain YmaF PF12788.2 EPS33301.1 - 0.14 12.3 2.3 0.28 11.3 0.6 2.2 2 0 0 2 2 2 0 YmaF family Tim17 PF02466.14 EPS33302.1 - 4.2e-13 49.4 6.1 7.1e-13 48.7 4.2 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family UCH PF00443.24 EPS33303.1 - 3.3e-49 167.4 0.0 8.4e-49 166.0 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 EPS33303.1 - 3.3e-48 160.9 0.1 3.5e-20 71.1 0.0 4.7 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH_1 PF13423.1 EPS33303.1 - 5.8e-13 48.9 0.1 3.5e-07 29.9 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUF2746 PF10874.3 EPS33303.1 - 0.0081 16.3 0.3 0.024 14.8 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2746) CoA_trans PF01144.18 EPS33304.1 - 1e-103 345.1 1.0 6.6e-62 208.5 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase Rrn6 PF10214.4 EPS33305.1 - 0.12 10.4 0.4 0.11 10.5 0.3 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF2370 PF10176.4 EPS33306.1 - 9.2e-87 290.2 0.3 1.5e-86 289.5 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2370) Pkinase PF00069.20 EPS33308.1 - 7.2e-71 238.3 0.0 9.1e-71 238.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS33308.1 - 1.2e-30 106.4 0.0 1.8e-30 105.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPS33308.1 - 0.07 12.8 0.1 0.07 12.8 0.1 2.3 2 2 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EPS33308.1 - 0.083 11.9 0.0 0.23 10.4 0.0 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Lipase_GDSL_2 PF13472.1 EPS33308.1 - 0.087 12.9 0.2 9.6 6.2 0.1 2.2 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family tRNA-synt_2b PF00587.20 EPS33309.1 - 5.2e-46 156.3 0.1 8.1e-46 155.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EPS33309.1 - 9.3e-18 63.9 0.3 2e-17 62.9 0.2 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.9 EPS33309.1 - 8.5e-15 54.3 0.0 1.6e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.16 EPS33309.1 - 9.5e-07 28.5 0.0 2.2e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 TGS domain Gar1 PF04410.9 EPS33310.1 - 1.2e-42 144.9 1.6 2.1e-42 144.2 0.0 1.8 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region CDP-OH_P_transf PF01066.16 EPS33311.1 - 3.7e-12 46.4 5.3 5.9e-12 45.7 3.7 1.6 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase MACPF PF01823.14 EPS33312.1 - 3.5e-10 39.9 1.0 9.7e-10 38.4 0.5 1.8 1 1 1 2 2 2 1 MAC/Perforin domain PGM_PMM_I PF02878.11 EPS33312.1 - 0.074 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I Ribosomal_L44 PF00935.14 EPS33315.1 - 0.39 10.7 2.3 0.59 10.1 1.6 1.2 1 0 0 1 1 1 0 Ribosomal protein L44 WSC PF01822.14 EPS33316.1 - 2.2e-16 59.5 9.4 5.9e-16 58.1 6.5 1.8 1 0 0 1 1 1 1 WSC domain SKG6 PF08693.5 EPS33316.1 - 6.7e-08 31.7 0.5 1.4e-07 30.6 0.4 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rab5ip PF07019.7 EPS33316.1 - 0.0056 16.7 1.2 0.011 15.8 0.8 1.4 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) Serglycin PF04360.7 EPS33316.1 - 0.011 15.4 2.6 0.02 14.6 1.8 1.5 1 0 0 1 1 1 0 Serglycin DUF1052 PF06319.7 EPS33317.1 - 0.016 14.4 0.0 0.021 14.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1052) Enamelin PF15362.1 EPS33318.1 - 0.22 9.5 0.7 0.23 9.5 0.5 1.0 1 0 0 1 1 1 0 Enamelin zf-C2H2_4 PF13894.1 EPS33320.1 - 6.1e-07 29.3 13.9 0.00014 21.9 2.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EPS33320.1 - 2.9e-05 24.1 14.1 0.012 15.8 3.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-CGNR PF11706.3 EPS33320.1 - 0.94 9.0 5.1 0.51 9.8 0.7 2.3 2 0 0 2 2 2 0 CGNR zinc finger Ifi-6-16 PF06140.8 EPS33324.1 - 0.00043 20.0 6.3 0.00065 19.4 4.4 1.3 1 0 0 1 1 1 1 Interferon-induced 6-16 family Ifi-6-16 PF06140.8 EPS33325.1 - 0.00044 19.9 13.4 0.00069 19.3 9.3 1.3 1 0 0 1 1 1 1 Interferon-induced 6-16 family Clusterin PF01093.12 EPS33326.1 - 0.17 10.6 1.0 0.27 10.0 0.7 1.3 1 0 0 1 1 1 0 Clusterin Nic96 PF04097.9 EPS33329.1 - 0.077 11.1 0.3 0.09 10.8 0.2 1.0 1 0 0 1 1 1 0 Nup93/Nic96 Pneumo_att_G PF05539.6 EPS33329.1 - 0.097 12.0 0.6 0.094 12.0 0.4 1.0 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G MFS_1 PF07690.11 EPS33330.1 - 3.5e-45 154.2 33.6 3.5e-45 154.2 23.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS33330.1 - 3.3e-09 35.8 30.2 7.3e-09 34.7 9.0 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.15 EPS33330.1 - 0.0082 14.2 6.7 1.8 6.5 0.1 3.4 2 1 1 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family TPMT PF05724.6 EPS33331.1 - 2e-25 89.5 0.0 6.3e-25 87.8 0.0 1.7 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_18 PF12847.2 EPS33331.1 - 2.9e-05 24.5 0.0 4.6e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPS33331.1 - 7e-05 23.2 0.0 0.00013 22.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPS33331.1 - 0.00014 21.8 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPS33331.1 - 0.0058 16.3 0.0 0.0074 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPS33331.1 - 0.0066 16.0 0.0 0.013 15.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPS33331.1 - 0.079 13.4 0.0 0.17 12.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 EPS33331.1 - 0.098 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB OTU PF02338.14 EPS33332.1 - 9.1e-17 61.7 4.4 1.8e-16 60.7 0.3 2.7 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EPS33332.1 - 5.8e-06 25.8 1.0 0.0008 18.8 0.0 2.7 3 0 0 3 3 3 2 Peptidase C65 Otubain OmpH PF03938.9 EPS33332.1 - 4.2 7.2 15.8 8.4 6.3 5.2 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) DUF1387 PF07139.6 EPS33332.1 - 8.2 5.9 14.2 13 5.2 9.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) adh_short_C2 PF13561.1 EPS33333.1 - 1e-27 97.5 0.0 1.2e-27 97.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EPS33333.1 - 5.2e-27 94.7 0.0 7.2e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPS33333.1 - 1.2e-08 34.8 0.0 2.2e-08 33.9 0.0 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EPS33333.1 - 0.12 12.3 0.1 0.49 10.3 0.1 2.0 1 1 0 1 1 1 0 NADH(P)-binding Trehalase PF01204.13 EPS33334.1 - 6.3e-192 638.7 0.1 7.4e-192 638.5 0.1 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 EPS33334.1 - 4.6e-17 61.0 0.8 7.2e-17 60.3 0.6 1.3 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain ICL PF00463.16 EPS33335.1 - 1.4e-287 954.0 4.0 1.6e-287 953.8 2.8 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EPS33335.1 - 1.4e-12 47.3 0.1 5.6e-12 45.4 0.0 1.9 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase DUF1842 PF08896.5 EPS33335.1 - 0.024 14.3 0.0 0.08 12.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1842) STb_secrete PF09075.5 EPS33335.1 - 0.041 13.7 0.1 0.097 12.5 0.1 1.6 1 0 0 1 1 1 0 Heat-stable enterotoxin B, secretory PT-TG PF14449.1 EPS33335.1 - 0.067 12.9 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 Pre-toxin TG Aldedh PF00171.17 EPS33336.1 - 1.1e-78 264.7 0.0 1.4e-78 264.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1767 PF08585.7 EPS33336.1 - 0.17 12.1 0.0 1.4 9.2 0.0 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF1767) Aa_trans PF01490.13 EPS33338.1 - 4e-20 71.6 34.9 4.8e-20 71.4 24.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein IBV_3C PF03620.8 EPS33338.1 - 0.047 13.5 1.0 0.58 10.0 0.2 3.0 2 0 0 2 2 2 0 IBV 3C protein Adap_comp_sub PF00928.16 EPS33339.1 - 3.8e-50 170.4 0.0 1.7e-49 168.2 0.0 2.1 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EPS33339.1 - 0.00052 19.7 0.2 0.00087 19.0 0.1 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain MAP65_ASE1 PF03999.7 EPS33339.1 - 7 5.1 6.4 9.5 4.6 4.4 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF4536 PF15055.1 EPS33340.1 - 0.00043 20.3 0.6 0.0011 18.9 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4536) DUF4588 PF15251.1 EPS33341.1 - 0.0027 17.7 7.1 0.013 15.4 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4588) SNF2_N PF00176.18 EPS33342.1 - 1.4e-79 267.0 0.0 2.3e-79 266.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 EPS33342.1 - 2.2e-45 153.1 1.9 7.6e-45 151.4 1.3 2.0 1 0 0 1 1 1 1 SLIDE HAND PF09110.6 EPS33342.1 - 4.8e-32 110.6 1.1 4.8e-32 110.6 0.8 3.5 2 0 0 2 2 2 1 HAND Helicase_C PF00271.26 EPS33342.1 - 6.5e-15 54.7 0.0 4.8e-14 51.9 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EPS33342.1 - 9.2e-08 31.2 0.0 2.4e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 EPS33342.1 - 2.3e-07 30.8 0.0 2.1e-06 27.7 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EPS33342.1 - 2.1e-05 24.0 0.0 5.4e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_14 PF13173.1 EPS33342.1 - 0.012 15.4 0.6 0.061 13.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EPS33342.1 - 0.013 15.6 0.3 0.22 11.6 0.0 3.0 2 0 0 2 2 2 0 AAA domain DEAD_2 PF06733.10 EPS33342.1 - 0.014 14.8 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 DEAD_2 Asp PF00026.18 EPS33343.1 - 2.7e-66 223.9 5.8 3.2e-66 223.7 4.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EPS33343.1 - 1.4e-07 31.5 0.0 1.3e-06 28.4 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EPS33343.1 - 0.053 14.0 2.3 9.1 6.8 0.4 3.1 2 1 0 2 2 2 0 Aspartyl protease ADH_zinc_N PF00107.21 EPS33344.1 - 3.9e-24 84.6 1.1 6.9e-24 83.8 0.8 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPS33344.1 - 2.1e-19 69.2 0.9 3.1e-19 68.7 0.6 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EPS33344.1 - 1.4e-07 32.4 0.2 3.6e-07 31.1 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ThiF PF00899.16 EPS33344.1 - 0.085 12.6 0.2 0.19 11.5 0.1 1.6 2 0 0 2 2 2 0 ThiF family SpoU_methylase PF00588.14 EPS33345.1 - 1.7e-25 89.5 0.1 2.2e-24 85.9 0.1 2.2 1 1 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 EPS33345.1 - 8.2e-07 29.1 0.0 1.8e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding zf-PHD-like PF15446.1 EPS33346.1 - 2e-63 212.8 14.1 4e-63 211.8 9.8 1.6 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.18 EPS33346.1 - 4.8e-56 189.7 0.1 6.7e-56 189.2 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPS33346.1 - 1.3e-14 53.7 0.0 3e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EPS33346.1 - 9.5e-11 41.0 1.2 2.4e-10 39.7 0.8 1.6 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 PHD PF00628.24 EPS33346.1 - 2.7e-07 30.1 20.4 7.4e-06 25.5 3.2 3.3 3 1 1 4 4 4 2 PHD-finger Chromo PF00385.19 EPS33346.1 - 6.9e-06 25.6 5.6 0.016 14.9 0.8 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DEAD PF00270.24 EPS33346.1 - 0.011 15.2 0.0 0.028 13.9 0.0 1.7 1 0 0 1 1 1 0 DEAD/DEAH box helicase ResIII PF04851.10 EPS33346.1 - 0.021 14.6 0.0 0.061 13.1 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF1087 PF06465.8 EPS33346.1 - 0.56 10.1 8.1 0.096 12.6 1.9 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) MRP-S28 PF10213.4 EPS33348.1 - 4.6e-42 143.0 0.0 1e-41 141.9 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein Glyco_tran_28_C PF04101.11 EPS33349.1 - 5.5e-21 74.9 0.0 1.4e-20 73.6 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EPS33349.1 - 0.0029 16.8 0.0 0.0047 16.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 1 UDPGT PF00201.13 EPS33349.1 - 0.022 13.2 0.1 0.049 12.1 0.1 1.6 1 1 1 2 2 2 0 UDP-glucoronosyl and UDP-glucosyl transferase Actin PF00022.14 EPS33350.1 - 3.6e-131 437.2 0.0 4.1e-131 437.0 0.0 1.0 1 0 0 1 1 1 1 Actin ADH_N PF08240.7 EPS33351.1 - 6.9e-25 86.9 5.8 1.1e-24 86.2 4.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPS33351.1 - 5.5e-16 58.2 0.0 1.6e-15 56.8 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EPS33351.1 - 0.00016 20.8 0.1 0.00032 19.9 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EPS33351.1 - 0.045 13.3 0.1 0.19 11.2 0.0 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Anillin PF08174.6 EPS33353.1 - 0.037 14.0 0.1 0.039 14.0 0.0 1.1 1 0 0 1 1 1 0 Cell division protein anillin DUF3602 PF12223.3 EPS33354.1 - 1e-21 77.0 15.6 1.4e-15 57.3 2.3 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Chlam_PMP PF02415.12 EPS33354.1 - 0.25 11.6 2.2 1.7 9.0 0.0 2.9 3 1 0 3 3 3 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Sporozoite_P67 PF05642.6 EPS33354.1 - 0.68 7.7 4.4 1 7.1 3.0 1.4 1 1 0 1 1 1 0 Sporozoite P67 surface antigen zf-U1 PF06220.7 EPS33357.1 - 4e-16 58.2 2.1 6e-16 57.7 1.4 1.3 1 0 0 1 1 1 1 U1 zinc finger TRP PF06011.7 EPS33358.1 - 3.4e-157 523.5 22.8 5e-157 522.9 15.8 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EPS33358.1 - 3.2e-38 130.9 0.0 5.2e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 ML-like domain DUF843 PF05814.6 EPS33358.1 - 0.004 16.9 4.7 0.42 10.4 0.0 3.3 2 1 1 3 3 3 2 Baculovirus protein of unknown function (DUF843) gpUL132 PF11359.3 EPS33358.1 - 0.047 13.0 0.0 0.047 13.0 0.0 1.7 2 0 0 2 2 2 0 Glycoprotein UL132 Shisa PF13908.1 EPS33358.1 - 0.69 10.0 2.6 6.9 6.8 0.1 2.6 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator DEAD PF00270.24 EPS33359.1 - 2.1e-43 147.7 0.2 4.1e-43 146.7 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EPS33359.1 - 2.2e-21 75.1 0.1 4.1e-21 74.2 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EPS33359.1 - 2.8e-21 75.1 0.0 6.7e-21 73.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Daxx PF03344.10 EPS33359.1 - 7.3 4.9 18.8 10 4.4 13.0 1.1 1 0 0 1 1 1 0 Daxx Family HAD_2 PF13419.1 EPS33362.1 - 1.3e-14 54.7 0.0 4.8e-14 52.9 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPS33362.1 - 4.4e-10 40.3 0.0 2.7e-07 31.1 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EPS33362.1 - 2e-08 33.8 0.0 3.3e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EPS33362.1 - 1e-05 25.8 0.0 1.4e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 EPS33362.1 - 0.0022 17.3 0.0 0.25 10.6 0.0 2.2 2 0 0 2 2 2 2 Mitochondrial PGP phosphatase Hydrolase_6 PF13344.1 EPS33362.1 - 0.13 12.1 0.0 2 8.3 0.0 2.4 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase zf-CCHC PF00098.18 EPS33363.1 - 0.0035 17.2 1.7 0.0035 17.2 1.2 4.0 4 0 0 4 4 4 2 Zinc knuckle ORMDL PF04061.9 EPS33364.1 - 7.5e-61 203.6 3.8 9e-61 203.3 2.6 1.1 1 0 0 1 1 1 1 ORMDL family Trep_Strep PF09605.5 EPS33364.1 - 0.12 12.0 1.3 0.16 11.5 0.5 1.5 1 1 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF1338 PF07063.8 EPS33365.1 - 0.067 12.2 0.1 0.1 11.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1338) CH PF00307.26 EPS33366.1 - 5e-13 49.0 0.0 7.9e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.6 EPS33366.1 - 0.18 11.8 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 CDC24 Calponin AMP-binding PF00501.23 EPS33367.1 - 6.9e-74 248.7 0.0 9.2e-74 248.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EPS33367.1 - 3.7e-58 196.3 0.0 5.2e-58 195.8 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 EPS33367.1 - 1.9e-12 47.2 0.0 4.2e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EPS33367.1 - 3.9e-11 42.8 0.0 1.1e-10 41.3 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPS33367.1 - 1.2e-09 37.3 0.0 1.8e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.1 EPS33367.1 - 8.2e-06 26.6 0.0 6.6e-05 23.7 0.0 2.6 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain Polysacc_synt_2 PF02719.10 EPS33367.1 - 0.0062 15.4 0.0 0.0091 14.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 EPS33367.1 - 0.012 15.8 0.0 0.031 14.5 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 EPS33367.1 - 0.049 13.5 1.2 0.11 12.4 0.1 2.1 2 0 0 2 2 2 0 short chain dehydrogenase KR PF08659.5 EPS33367.1 - 0.15 11.7 0.1 0.37 10.4 0.1 1.7 1 0 0 1 1 1 0 KR domain NDUFA12 PF05071.11 EPS33368.1 - 1.3e-12 48.1 3.5 1.7e-12 47.7 0.1 2.2 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 Piwi PF02171.12 EPS33372.1 - 2.4e-62 210.6 0.0 4e-62 209.9 0.0 1.4 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 EPS33372.1 - 8.8e-12 44.4 0.4 2.9e-11 42.8 0.0 2.0 2 0 0 2 2 2 1 PAZ domain DUF1785 PF08699.5 EPS33372.1 - 1.7e-09 36.8 0.0 5.1e-09 35.3 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) EMP24_GP25L PF01105.19 EPS33374.1 - 9.1e-41 139.5 0.0 1e-40 139.3 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Sdh5 PF03937.11 EPS33375.1 - 2.1e-23 81.7 0.1 4.1e-23 80.8 0.1 1.4 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase WD40 PF00400.27 EPS33376.1 - 2e-61 201.8 25.4 2.8e-12 45.9 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EPS33376.1 - 0.00052 18.2 6.6 0.39 8.8 0.1 3.8 2 1 1 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EPS33376.1 - 0.0024 16.2 0.1 0.49 8.6 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain TPR_12 PF13424.1 EPS33377.1 - 2.4e-11 43.4 6.9 0.00068 19.5 0.1 4.3 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 EPS33377.1 - 0.0034 16.9 6.6 3.4 7.4 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EPS33377.1 - 0.0038 17.0 11.3 1.1 9.3 0.1 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 EPS33377.1 - 0.0041 16.7 4.4 1.5 8.7 0.3 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EPS33377.1 - 0.0047 16.5 5.0 4 7.1 0.2 4.1 2 1 1 3 3 3 1 TPR repeat VEK-30 PF12107.3 EPS33377.1 - 0.13 12.0 0.3 5.7 6.7 0.2 2.6 2 0 0 2 2 2 0 Plasminogen (Pg) ligand in fibrinolytic pathway TPR_16 PF13432.1 EPS33377.1 - 0.51 11.0 8.0 43 4.9 1.0 4.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 EPS33377.1 - 0.57 10.0 12.7 1.6 8.6 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF159 PF02586.9 EPS33378.1 - 3.3e-57 193.3 0.0 4.6e-57 192.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 Med1 PF10744.4 EPS33380.1 - 2.9e-91 306.1 0.0 4.1e-91 305.6 0.0 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 Cir_N PF10197.4 EPS33380.1 - 0.1 12.6 0.8 0.33 10.9 0.6 1.9 1 0 0 1 1 1 0 N-terminal domain of CBF1 interacting co-repressor CIR Gln-synt_C PF00120.19 EPS33384.1 - 3.2e-58 196.9 0.0 3.9e-58 196.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EPS33384.1 - 3.5e-21 74.5 0.0 6e-21 73.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain MFS_1 PF07690.11 EPS33385.1 - 5e-37 127.4 44.8 2.1e-31 108.9 19.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 EPS33385.1 - 0.009 15.5 5.0 0.0091 15.4 2.3 1.9 1 1 1 2 2 2 1 Ion channel regulatory protein UNC-93 FPN1 PF06963.7 EPS33385.1 - 0.037 12.3 3.5 0.037 12.4 1.2 1.8 2 0 0 2 2 2 0 Ferroportin1 (FPN1) Choline_transpo PF04515.7 EPS33385.1 - 2.3 6.8 9.8 0.23 10.1 2.3 2.3 3 0 0 3 3 3 0 Plasma-membrane choline transporter zf-CCHC PF00098.18 EPS33386.1 - 6.7e-16 57.3 40.3 0.00035 20.3 1.5 6.3 6 0 0 6 6 6 5 Zinc knuckle zf-CCHC_4 PF14392.1 EPS33386.1 - 1.6e-06 27.7 24.7 0.071 12.7 0.2 5.4 4 1 1 5 5 5 5 Zinc knuckle CitX PF03802.9 EPS33386.1 - 0.007 15.8 2.9 0.32 10.4 0.1 2.6 1 1 1 2 2 2 2 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase zf-CCHC_3 PF13917.1 EPS33386.1 - 0.02 14.6 1.0 0.02 14.6 0.7 4.2 3 1 1 4 4 4 0 Zinc knuckle PHF5 PF03660.9 EPS33386.1 - 7.9 6.5 13.9 0.45 10.6 4.8 2.2 2 0 0 2 2 2 0 PHF5-like protein DUF846 PF05832.7 EPS33387.1 - 7e-46 155.4 7.0 8.2e-46 155.2 4.9 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Tic20 PF09685.5 EPS33387.1 - 4.3 7.3 11.3 5.7 6.9 0.7 2.2 2 0 0 2 2 2 0 Tic20-like protein DUF1771 PF08590.5 EPS33388.1 - 2.5e-16 59.4 9.7 2.5e-16 59.4 6.7 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 EPS33388.1 - 1.7e-12 47.3 0.1 8.1e-12 45.1 0.0 2.2 1 0 0 1 1 1 1 Smr domain zf-CCCH PF00642.19 EPS33388.1 - 9e-07 28.4 1.4 0.0046 16.6 0.0 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CUE PF02845.11 EPS33388.1 - 0.027 13.9 2.1 0.04 13.3 0.1 2.3 2 0 0 2 2 2 0 CUE domain SNARE_assoc PF09335.6 EPS33389.1 - 6.6e-13 48.9 7.6 2.4e-12 47.1 3.9 2.5 2 1 0 2 2 2 1 SNARE associated Golgi protein 7tm_1 PF00001.16 EPS33389.1 - 0.00018 20.7 1.8 0.00028 20.1 1.3 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) GtrA PF04138.9 EPS33389.1 - 1.7 8.5 11.2 3.5 7.6 6.0 2.1 2 0 0 2 2 2 0 GtrA-like protein DUF3186 PF11382.3 EPS33389.1 - 2.9 6.9 4.5 0.41 9.7 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3186) Amino_oxidase PF01593.19 EPS33390.1 - 4.2e-94 316.1 0.3 6.1e-94 315.6 0.2 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.12 EPS33390.1 - 1.2e-13 50.9 0.0 2.3e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.1 EPS33390.1 - 6.6e-08 32.4 0.0 2e-07 30.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.14 EPS33390.1 - 9.1e-05 22.6 4.3 0.00034 20.8 0.4 2.8 1 1 1 2 2 2 1 HMG (high mobility group) box NAD_binding_9 PF13454.1 EPS33390.1 - 0.011 15.5 0.6 0.27 11.0 0.0 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding HMG_box_2 PF09011.5 EPS33390.1 - 0.067 13.5 0.3 0.16 12.3 0.2 1.6 1 0 0 1 1 1 0 HMG-box domain Pyr_redox_3 PF13738.1 EPS33390.1 - 0.073 13.1 0.0 0.47 10.4 0.0 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPS33390.1 - 0.12 12.8 0.1 2.3 8.6 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPS33392.1 - 2.5e-27 96.0 0.0 3.3e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPS33392.1 - 2.8e-15 56.4 0.2 2.4e-13 50.3 0.0 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPS33392.1 - 1.5e-09 38.2 0.0 5.7e-06 26.5 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPS33392.1 - 4e-05 23.5 0.9 0.028 14.4 0.0 2.9 3 0 0 3 3 3 2 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 EPS33392.1 - 0.00011 22.3 0.0 0.0093 16.2 0.0 2.7 2 1 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.12 EPS33392.1 - 0.00083 18.5 0.1 0.0051 15.9 0.0 2.2 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.1 EPS33392.1 - 0.001 18.1 0.2 0.42 9.4 0.0 2.9 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EPS33392.1 - 0.0034 16.3 1.5 9.7 4.9 0.0 3.4 2 2 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EPS33392.1 - 0.0057 15.7 1.0 8.3 5.3 0.0 3.0 2 1 1 3 3 3 2 FAD binding domain Shikimate_DH PF01488.15 EPS33392.1 - 0.021 14.9 0.1 1.2 9.1 0.0 2.5 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.2 EPS33392.1 - 0.036 13.1 0.2 2.1 7.3 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.17 EPS33392.1 - 0.078 11.8 4.6 10 4.8 0.1 4.0 3 2 2 5 5 5 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EPS33392.1 - 0.2 10.4 3.9 0.86 8.3 0.2 3.2 3 1 1 4 4 4 0 FAD binding domain Peptidase_S8 PF00082.17 EPS33395.1 - 2.8e-51 174.3 1.1 2.8e-51 174.3 0.8 1.5 2 0 0 2 2 2 1 Subtilase family P_proprotein PF01483.15 EPS33395.1 - 3e-29 100.6 0.3 5.8e-29 99.7 0.2 1.5 1 0 0 1 1 1 1 Proprotein convertase P-domain PX PF00787.19 EPS33396.1 - 6.4e-19 67.8 0.3 1.6e-18 66.5 0.2 1.6 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 EPS33396.1 - 1.3e-16 60.5 5.7 2.2e-09 36.9 0.2 2.1 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 EPS33396.1 - 2.9e-06 26.9 2.2 7e-06 25.7 1.5 1.7 1 1 0 1 1 1 1 BAR domain DUF724 PF05266.9 EPS33396.1 - 0.02 14.5 1.2 5.5 6.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF724) IncA PF04156.9 EPS33396.1 - 0.028 14.0 3.5 0.2 11.2 0.1 2.2 2 0 0 2 2 2 0 IncA protein FAD_binding_3 PF01494.14 EPS33397.1 - 5.3e-20 71.7 0.0 1e-16 60.9 0.0 3.0 2 1 0 2 2 2 2 FAD binding domain SE PF08491.5 EPS33397.1 - 9.6e-07 27.8 0.0 1.5e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 EPS33397.1 - 0.00057 18.8 0.0 0.07 12.0 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EPS33397.1 - 0.0011 17.9 0.1 0.0063 15.4 0.0 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EPS33397.1 - 0.0025 17.6 0.0 0.0048 16.6 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EPS33397.1 - 0.022 13.6 0.0 0.04 12.8 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EPS33397.1 - 0.027 14.3 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EPS33397.1 - 0.06 11.9 0.0 0.57 8.7 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.9 EPS33397.1 - 0.07 11.5 0.0 0.099 11.0 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_8 PF13450.1 EPS33397.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EPS33397.1 - 0.19 10.7 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family tRNA-synt_His PF13393.1 EPS33398.1 - 1.3e-37 129.4 0.0 1.7e-31 109.4 0.0 2.1 2 0 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EPS33398.1 - 8.2e-17 61.3 0.0 1.6e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EPS33398.1 - 5.2e-14 51.9 0.0 1e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.2 EPS33398.1 - 0.00063 18.9 0.0 0.0023 17.1 0.0 1.8 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.15 EPS33398.1 - 0.0016 17.3 0.2 0.089 11.5 0.0 2.6 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) UCH PF00443.24 EPS33400.1 - 1.9e-64 217.3 0.2 3.5e-64 216.5 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPS33400.1 - 2.6e-33 115.7 1.2 1.3e-24 87.1 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 EPS33400.1 - 0.018 14.3 4.7 0.098 11.9 1.5 2.8 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Ycf1 PF05758.7 EPS33400.1 - 0.31 8.7 2.6 0.53 7.9 1.8 1.3 1 0 0 1 1 1 0 Ycf1 Yos1 PF08571.5 EPS33402.1 - 1.4e-32 111.6 1.0 1.6e-32 111.4 0.7 1.0 1 0 0 1 1 1 1 Yos1-like Glyco_transf_22 PF03901.12 EPS33403.1 - 1.6e-44 152.5 11.7 1.9e-44 152.3 8.1 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF3413 PF11893.3 EPS33403.1 - 0.0016 17.4 0.8 0.0016 17.4 0.6 2.3 4 0 0 4 4 4 1 Domain of unknown function (DUF3413) DUF3522 PF12036.3 EPS33403.1 - 0.018 14.8 0.4 0.046 13.5 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3522) Complex1_49kDa PF00346.14 EPS33404.1 - 1.1e-133 444.3 0.0 1.5e-133 443.9 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit RNA_pol_A_bac PF01000.21 EPS33405.1 - 1.1e-24 86.7 0.0 2e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EPS33405.1 - 1.4e-12 46.5 0.0 1.9e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain ThiF PF00899.16 EPS33406.1 - 3e-39 133.9 0.1 8.8e-39 132.4 0.0 1.7 2 0 0 2 2 2 1 ThiF family E2_bind PF08825.5 EPS33406.1 - 5.9e-29 99.6 0.0 1.1e-28 98.7 0.0 1.5 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 EPS33406.1 - 3.4e-23 80.9 0.2 6.1e-23 80.1 0.1 1.4 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EPS33406.1 - 3.8e-14 51.8 3.3 3.8e-14 51.8 2.3 1.7 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 EPS33406.1 - 7.5e-05 22.8 0.1 0.00022 21.3 0.0 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase MoeZ_MoeB PF05237.8 EPS33406.1 - 0.00015 21.3 0.0 0.00031 20.2 0.0 1.5 1 0 0 1 1 1 1 MoeZ/MoeB domain UBA_e1_C PF09358.5 EPS33406.1 - 0.079 13.1 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-activating enzyme e1 C-terminal domain Ecm33 PF12454.3 EPS33406.1 - 0.084 12.7 0.4 0.18 11.7 0.3 1.5 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Pyr_redox PF00070.22 EPS33406.1 - 0.1 13.0 0.0 0.25 11.7 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EPS33406.1 - 0.12 12.3 0.2 0.28 11.2 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain Telomere_reg-2 PF10193.4 EPS33407.1 - 1.1e-33 115.9 0.0 2.6e-33 114.6 0.0 1.7 1 0 0 1 1 1 1 Telomere length regulation protein Ebola_NP PF05505.7 EPS33407.1 - 0.43 8.5 3.7 0.72 7.8 2.6 1.3 1 0 0 1 1 1 0 Ebola nucleoprotein FYDLN_acid PF09538.5 EPS33407.1 - 6 7.4 9.0 30 5.2 3.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Sec1 PF00995.18 EPS33408.1 - 8.8e-133 443.9 0.0 1e-132 443.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family SNARE PF05739.14 EPS33409.1 - 0.00048 19.7 5.1 0.00055 19.5 0.4 2.9 3 0 0 3 3 3 1 SNARE domain Fork_head PF00250.13 EPS33409.1 - 0.065 13.2 0.1 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 Fork head domain zf-H2C2_2 PF13465.1 EPS33410.1 - 1.4e-11 44.0 15.4 5.9e-06 26.3 0.2 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EPS33410.1 - 6.4e-10 38.7 11.6 1.8e-05 24.7 3.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPS33410.1 - 2.4e-07 30.5 8.3 0.00019 21.5 1.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EPS33410.1 - 5.9e-06 26.2 1.5 1.8e-05 24.7 1.0 1.9 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EPS33410.1 - 5.7e-05 23.1 5.7 0.00011 22.2 1.4 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EPS33410.1 - 0.00016 21.4 6.9 0.0037 17.1 1.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EPS33410.1 - 0.055 13.5 1.1 0.055 13.5 0.7 1.6 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 EPS33410.1 - 0.52 10.0 3.8 5.6 6.7 0.2 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-BED PF02892.10 EPS33410.1 - 0.69 9.7 5.1 0.24 11.1 0.5 2.1 2 0 0 2 2 2 0 BED zinc finger zf-H2C2_5 PF13909.1 EPS33410.1 - 4.1 7.8 8.7 6.1 7.2 1.2 3.2 2 1 1 3 3 3 0 C2H2-type zinc-finger domain Nepo_coat PF03391.10 EPS33411.1 - 0.089 12.0 0.1 0.12 11.6 0.1 1.2 1 0 0 1 1 1 0 Nepovirus coat protein, central domain SF3b1 PF08920.5 EPS33416.1 - 2.5e-34 118.4 1.6 6.6e-33 113.7 1.1 2.5 1 1 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 EPS33416.1 - 5.7e-16 58.5 1.5 0.011 16.0 0.0 7.6 6 3 4 10 10 10 6 HEAT repeats HEAT PF02985.17 EPS33416.1 - 5.6e-11 41.5 11.5 0.38 10.9 0.2 9.2 10 0 0 10 10 10 3 HEAT repeat HEAT_EZ PF13513.1 EPS33416.1 - 3.3e-10 40.1 3.3 0.53 10.8 0.0 8.0 7 2 2 9 9 9 2 HEAT-like repeat Adaptin_N PF01602.15 EPS33416.1 - 1.1e-06 27.2 0.6 0.0017 16.7 0.1 3.3 2 2 1 3 3 3 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 EPS33416.1 - 1.9e-05 24.9 0.6 1.3 9.4 0.0 5.4 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EPS33416.1 - 0.0059 15.9 0.2 1 8.6 0.0 3.2 3 0 0 3 3 3 1 CLASP N terminal DUF2435 PF10363.4 EPS33416.1 - 0.012 15.5 0.6 1.5 8.8 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2435) NUC173 PF08161.7 EPS33416.1 - 0.026 13.8 0.3 22 4.3 0.0 3.9 4 0 0 4 4 4 0 NUC173 domain Cnd1 PF12717.2 EPS33416.1 - 0.032 14.0 2.9 35 4.1 0.0 4.9 6 1 0 6 6 6 0 non-SMC mitotic condensation complex subunit 1 B56 PF01603.15 EPS33416.1 - 0.053 12.1 0.0 0.59 8.6 0.0 2.6 2 1 1 3 3 3 0 Protein phosphatase 2A regulatory B subunit (B56 family) NodA PF02474.10 EPS33416.1 - 0.059 12.6 0.0 0.16 11.2 0.0 1.7 1 0 0 1 1 1 0 Nodulation protein A (NodA) APH PF01636.18 EPS33417.1 - 9.9e-10 38.5 0.0 1.5e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EPS33417.1 - 0.0098 15.0 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase DUF3455 PF11937.3 EPS33420.1 - 4.3e-38 131.0 0.0 5.5e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) SAP PF02037.22 EPS33421.1 - 1.4e-11 43.6 0.1 3.5e-11 42.3 0.1 1.7 1 0 0 1 1 1 1 SAP domain Transthyretin PF00576.16 EPS33421.1 - 0.038 13.8 0.2 0.49 10.3 0.0 2.3 1 1 1 2 2 2 0 HIUase/Transthyretin family Methyltransf_11 PF08241.7 EPS33422.1 - 0.01 16.3 0.0 0.023 15.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Tmemb_cc2 PF10267.4 EPS33422.1 - 2.4 6.6 2.4 6.4 5.2 1.6 1.7 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Annexin PF00191.15 EPS33423.1 - 2.1e-59 197.3 0.8 2.9e-19 68.7 0.0 4.1 4 0 0 4 4 4 4 Annexin SH3_9 PF14604.1 EPS33424.1 - 1e-06 28.2 0.6 1e-06 28.2 0.4 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 EPS33424.1 - 0.00022 20.5 0.8 0.00047 19.4 0.6 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EPS33424.1 - 0.021 14.2 0.1 0.065 12.7 0.1 1.8 1 0 0 1 1 1 0 Variant SH3 domain HypA PF01155.14 EPS33424.1 - 1.2 8.8 12.4 3.7 7.2 1.0 3.6 3 0 0 3 3 3 0 Hydrogenase expression/synthesis hypA family CBM_21 PF03370.8 EPS33429.1 - 1e-34 118.9 2.9 1.8e-34 118.1 2.0 1.4 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit Histone PF00125.19 EPS33430.1 - 1.9e-15 56.7 0.3 2.3e-15 56.4 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EPS33430.1 - 4.9e-05 23.4 0.1 6.6e-05 23.0 0.1 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EPS33430.1 - 7.1e-05 22.6 0.2 0.0001 22.1 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EPS33430.1 - 0.00011 22.2 0.1 0.00019 21.4 0.1 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EPS33430.1 - 0.0026 17.4 0.0 0.0031 17.1 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated CENP-T PF15511.1 EPS33430.1 - 0.011 14.9 0.0 0.012 14.9 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID_20kDa PF03847.8 EPS33430.1 - 0.049 13.9 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Mito_carr PF00153.22 EPS33431.1 - 1.3e-46 156.2 1.3 9.1e-16 57.3 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF883 PF05957.8 EPS33431.1 - 0.043 14.2 1.4 0.097 13.0 0.2 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.2 EPS33431.1 - 0.1 12.9 1.4 19 5.7 0.1 2.8 2 0 0 2 2 2 0 YtxH-like protein EBP PF05241.7 EPS33432.1 - 1.9e-69 232.5 7.1 2.2e-69 232.3 4.9 1.0 1 0 0 1 1 1 1 Emopamil binding protein Velvet PF11754.3 EPS33435.1 - 0.007 15.9 0.0 0.0081 15.7 0.0 1.1 1 0 0 1 1 1 1 Velvet factor STT3 PF02516.9 EPS33437.1 - 0.14 11.0 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 Oligosaccharyl transferase STT3 subunit L31 PF09784.4 EPS33438.1 - 1.3e-47 160.0 3.0 1.5e-47 159.9 2.1 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 MADF_DNA_bdg PF10545.4 EPS33438.1 - 0.049 13.8 1.6 0.4 10.9 0.0 2.1 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF3121 PF11319.3 EPS33438.1 - 0.069 12.6 0.4 0.084 12.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3121) Lambda_tail_I PF06805.7 EPS33438.1 - 0.073 12.9 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage lambda tail assembly protein I Acyltransferase PF01553.16 EPS33439.1 - 2.2e-16 59.5 0.0 4.4e-16 58.5 0.0 1.5 1 1 0 1 1 1 1 Acyltransferase DEAD PF00270.24 EPS33441.1 - 1.1e-39 135.6 1.1 1.8e-39 134.9 0.7 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPS33441.1 - 8.3e-23 80.0 0.2 1.5e-11 43.9 0.0 3.1 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 EPS33441.1 - 0.00099 18.9 1.9 0.001 18.9 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2782 PF11191.3 EPS33441.1 - 0.026 14.4 0.0 0.082 12.8 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2782) AflR PF08493.5 EPS33441.1 - 0.11 11.5 0.1 0.19 10.7 0.1 1.4 1 0 0 1 1 1 0 Aflatoxin regulatory protein Methyltransf_6 PF03737.10 EPS33442.1 - 8.7e-19 67.9 1.0 4.2e-18 65.6 1.2 1.6 2 0 0 2 2 2 1 Demethylmenaquinone methyltransferase Thiolase_N PF00108.18 EPS33443.1 - 7.6e-79 264.4 1.9 1.5e-78 263.4 1.3 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EPS33443.1 - 2.4e-43 146.4 0.3 5.3e-43 145.3 0.2 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EPS33443.1 - 0.027 13.9 2.4 0.1 12.0 0.3 2.4 2 1 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EPS33443.1 - 0.063 12.9 0.3 16 5.2 0.0 2.7 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Drf_GBD PF06371.8 EPS33445.1 - 1.8e-15 56.8 1.3 4.1e-14 52.3 0.9 2.4 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EPS33445.1 - 0.048 13.0 0.0 0.13 11.6 0.0 1.7 1 0 0 1 1 1 0 Diaphanous FH3 Domain Nramp PF01566.13 EPS33446.1 - 8.4e-92 307.7 23.3 1.2e-91 307.1 16.2 1.2 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Snf7 PF03357.16 EPS33447.1 - 6.1e-42 142.8 14.7 7.3e-42 142.6 10.2 1.0 1 0 0 1 1 1 1 Snf7 DUF4201 PF13870.1 EPS33447.1 - 2.3e-05 23.9 6.2 2.3e-05 23.9 4.3 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4201) Zwint PF15556.1 EPS33447.1 - 0.0038 16.5 6.9 0.0049 16.1 4.8 1.2 1 0 0 1 1 1 1 ZW10 interactor DUF3584 PF12128.3 EPS33447.1 - 0.0045 14.4 6.4 0.006 13.9 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) NPV_P10 PF05531.7 EPS33447.1 - 0.0068 16.6 6.7 0.14 12.4 0.5 2.8 3 0 0 3 3 3 1 Nucleopolyhedrovirus P10 protein Reo_sigmaC PF04582.7 EPS33447.1 - 0.012 14.8 3.0 0.11 11.6 0.3 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein zf-C4H2 PF10146.4 EPS33447.1 - 0.033 14.1 4.3 0.044 13.8 2.9 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein IncA PF04156.9 EPS33447.1 - 0.042 13.4 6.8 9.2 5.8 4.7 2.2 1 1 0 1 1 1 0 IncA protein DUF1395 PF07160.7 EPS33447.1 - 0.043 13.3 4.3 0.58 9.6 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1395) Sec34 PF04136.10 EPS33447.1 - 0.078 12.6 4.7 1.6 8.4 1.7 2.1 1 1 1 2 2 2 0 Sec34-like family CDC37_N PF03234.9 EPS33447.1 - 0.11 12.8 6.0 0.15 12.3 4.2 1.3 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding HHH_2 PF12826.2 EPS33447.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif Exonuc_VII_L PF02601.10 EPS33447.1 - 0.13 11.4 3.2 0.16 11.1 2.2 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Mod_r PF07200.8 EPS33447.1 - 0.14 12.1 10.0 0.033 14.1 3.5 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Mnd1 PF03962.10 EPS33447.1 - 0.54 9.8 10.7 1.5 8.4 7.4 1.8 1 1 0 1 1 1 0 Mnd1 family DUF4140 PF13600.1 EPS33447.1 - 1.7 9.1 6.3 2.1 8.8 0.0 3.2 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Atg14 PF10186.4 EPS33447.1 - 3.7 6.4 9.2 9.5 5.0 6.4 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4337 PF14235.1 EPS33447.1 - 5.2 6.8 9.4 0.52 10.1 1.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) FliD_N PF02465.13 EPS33447.1 - 6.1 7.2 8.6 24 5.3 0.4 2.9 1 1 2 3 3 3 0 Flagellar hook-associated protein 2 N-terminus COG2 PF06148.6 EPS33447.1 - 6.3 6.6 7.7 7 6.5 0.6 2.9 1 1 2 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 APG6 PF04111.7 EPS33447.1 - 8.3 5.3 11.2 6.2 5.7 5.9 1.8 1 1 1 2 2 2 0 Autophagy protein Apg6 OmpH PF03938.9 EPS33447.1 - 9.7 6.1 14.6 1.1e+02 2.7 10.1 2.1 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) SAPS PF04499.10 EPS33448.1 - 4.2e-203 675.2 4.9 3.9e-202 672.0 0.0 2.9 3 0 0 3 3 3 1 SIT4 phosphatase-associated protein RRN3 PF05327.6 EPS33448.1 - 0.12 10.4 5.7 0.051 11.6 1.2 2.1 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 SET PF00856.23 EPS33449.1 - 0.041 14.1 0.0 0.22 11.8 0.0 2.1 2 0 0 2 2 2 0 SET domain Complex1_51K PF01512.12 EPS33450.1 - 8.4e-48 161.9 0.0 1.3e-47 161.2 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 EPS33450.1 - 1.9e-18 65.2 0.9 3.6e-18 64.4 0.6 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 EPS33450.1 - 1.3e-09 37.8 0.0 3.5e-09 36.4 0.0 1.8 1 0 0 1 1 1 1 SLBB domain Nup96 PF12110.3 EPS33451.1 - 2.4e-91 305.8 0.3 4.9e-91 304.8 0.0 1.6 2 0 0 2 2 2 1 Nuclear protein 96 Nucleoporin2 PF04096.9 EPS33451.1 - 3.4e-49 166.2 0.0 5.6e-49 165.5 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 EPS33451.1 - 3.1e-15 56.3 223.3 5.2e-07 29.9 32.9 9.7 5 3 6 11 11 11 6 Nucleoporin FG repeat region AMP-binding PF00501.23 EPS33452.1 - 3e-91 305.9 0.1 3.6e-91 305.6 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPS33452.1 - 8.8e-23 81.0 0.2 3.4e-20 72.7 0.2 2.7 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain PALP PF00291.20 EPS33453.1 - 1.7e-55 188.4 0.1 2e-55 188.1 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NAD_binding_7 PF13241.1 EPS33453.1 - 0.06 13.6 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding DAP_C PF07932.7 EPS33454.1 - 3.8e-42 142.3 0.1 8.1e-42 141.3 0.1 1.6 1 0 0 1 1 1 1 D-aminopeptidase, domain C Beta-lactamase PF00144.19 EPS33454.1 - 2.1e-37 128.9 0.0 2.9e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DAP_B PF07930.7 EPS33454.1 - 0.043 13.5 0.0 0.096 12.4 0.0 1.6 1 0 0 1 1 1 0 D-aminopeptidase, domain B Methyltransf_14 PF08484.6 EPS33454.1 - 0.2 11.2 0.0 6.9 6.2 0.0 2.3 2 0 0 2 2 2 0 C-methyltransferase C-terminal domain GET2 PF08690.5 EPS33455.1 - 1e-06 28.2 0.5 2e-06 27.2 0.1 1.6 2 0 0 2 2 2 1 GET complex subunit GET2 GFA PF04828.9 EPS33456.1 - 1.7e-14 53.5 0.8 5.3e-14 51.9 0.6 1.7 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Arrestin_C PF02752.17 EPS33457.1 - 6.3e-11 42.5 0.0 8.3e-09 35.6 0.0 2.2 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EPS33457.1 - 1.5e-05 24.8 0.0 0.00018 21.3 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain G_glu_transpept PF01019.16 EPS33457.1 - 0.083 11.3 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase C2 PF00168.25 EPS33458.1 - 1.9e-20 72.5 0.0 1.6e-13 50.3 0.0 2.7 2 0 0 2 2 2 2 C2 domain DUF2570 PF10828.3 EPS33458.1 - 1.1 8.8 4.7 2.9 7.5 3.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Cpl-7 PF08230.6 EPS33459.1 - 0.006 16.2 0.0 0.012 15.2 0.0 1.6 1 0 0 1 1 1 1 Cpl-7 lysozyme C-terminal domain FMN_red PF03358.10 EPS33460.1 - 9.1e-26 90.1 0.0 1.3e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase DnaJ PF00226.26 EPS33460.1 - 0.1 12.3 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 DnaJ domain Paf1 PF03985.8 EPS33461.1 - 0.39 9.3 9.3 0.52 8.9 6.5 1.1 1 0 0 1 1 1 0 Paf1 TATR PF03430.8 EPS33461.1 - 0.45 9.0 4.0 0.62 8.6 2.8 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator FLO_LFY PF01698.11 EPS33461.1 - 3.9 6.2 6.1 5.4 5.7 4.2 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein CDC45 PF02724.9 EPS33461.1 - 8.5 4.2 10.7 12 3.8 7.4 1.1 1 0 0 1 1 1 0 CDC45-like protein IMS PF00817.15 EPS33463.1 - 1.3e-34 119.1 0.0 2.4e-34 118.2 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EPS33463.1 - 8.1e-14 51.6 0.1 1.7e-13 50.5 0.1 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EPS33463.1 - 0.00037 20.3 0.0 0.0031 17.4 0.0 2.5 2 0 0 2 2 2 1 IMS family HHH motif Reprolysin_5 PF13688.1 EPS33464.1 - 2.9e-57 193.7 7.8 2.9e-57 193.7 5.4 2.0 2 1 0 2 2 2 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 EPS33464.1 - 2e-45 154.8 1.8 3.3e-45 154.1 1.3 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EPS33464.1 - 2.3e-43 148.2 2.3 5e-43 147.1 1.6 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 EPS33464.1 - 3.3e-19 68.8 33.1 3.3e-19 68.8 23.0 4.5 2 1 2 4 4 4 1 Disintegrin Reprolysin_3 PF13582.1 EPS33464.1 - 4.8e-19 69.0 0.1 1.8e-18 67.2 0.1 2.0 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Pep_M12B_propep PF01562.14 EPS33464.1 - 7.8e-06 25.7 0.0 1.4e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Reprolysin family propeptide WWbp PF10349.4 EPS33464.1 - 6.9 7.5 18.3 14 6.5 12.7 1.5 1 0 0 1 1 1 0 WW-domain ligand protein EF-hand_1 PF00036.27 EPS33465.1 - 9.7e-15 52.6 3.3 5.4e-05 22.2 0.0 3.9 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 EPS33465.1 - 9.7e-14 51.2 4.6 5.1e-08 32.9 0.1 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EPS33465.1 - 2.4e-13 48.7 7.5 1.1e-05 24.9 0.3 3.8 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 EPS33465.1 - 1.8e-10 40.2 2.9 3.1e-08 33.1 0.1 2.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_4 PF12763.2 EPS33465.1 - 0.012 15.3 0.1 0.044 13.5 0.0 2.0 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.1 EPS33465.1 - 0.31 10.4 12.2 0.3 10.5 0.5 3.5 4 0 0 4 4 4 0 EF hand Zn_clus PF00172.13 EPS33466.1 - 0.0011 18.7 13.6 0.0018 18.1 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MgsA_C PF12002.3 EPS33467.1 - 4.2e-57 192.5 0.0 6.4e-57 191.8 0.0 1.2 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 EPS33467.1 - 1e-13 51.6 0.0 2.5e-13 50.3 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EPS33467.1 - 5.8e-10 38.6 0.0 1.5e-09 37.2 0.0 1.6 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 EPS33467.1 - 4.1e-05 22.8 0.0 0.091 11.9 0.0 2.2 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EPS33467.1 - 5.8e-05 22.8 0.0 0.00056 19.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EPS33467.1 - 7e-05 22.3 0.0 0.0018 17.7 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.1 EPS33467.1 - 0.00036 20.6 0.2 0.0015 18.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EPS33467.1 - 0.00066 19.2 0.0 0.0026 17.3 0.0 2.0 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EPS33467.1 - 0.0013 18.4 0.0 0.003 17.2 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain DUF815 PF05673.8 EPS33467.1 - 0.0023 16.8 0.0 0.0037 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DUF927 PF06048.6 EPS33467.1 - 0.0038 16.5 0.2 0.0066 15.7 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF927) Sigma54_activ_2 PF14532.1 EPS33467.1 - 0.0079 16.2 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_14 PF13173.1 EPS33467.1 - 0.009 15.9 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPS33467.1 - 0.012 15.6 0.1 0.18 11.7 0.0 2.4 1 1 1 2 2 2 0 AAA ATPase domain ResIII PF04851.10 EPS33467.1 - 0.014 15.2 0.1 3.6 7.3 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit TIP49 PF06068.8 EPS33467.1 - 0.028 13.1 0.2 0.1 11.3 0.1 1.8 1 1 1 2 2 2 0 TIP49 C-terminus AAA_30 PF13604.1 EPS33467.1 - 0.028 13.9 0.2 0.091 12.3 0.1 1.7 1 1 1 2 2 2 0 AAA domain AAA_17 PF13207.1 EPS33467.1 - 0.04 14.7 0.0 0.1 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.9 EPS33467.1 - 0.11 11.4 0.1 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase NB-ARC PF00931.17 EPS33467.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.1 EPS33467.1 - 0.13 12.6 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain SKI PF01202.17 EPS33467.1 - 0.14 12.0 0.1 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase AAA_29 PF13555.1 EPS33467.1 - 0.16 11.5 0.1 9.4 5.8 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Aminotran_1_2 PF00155.16 EPS33468.1 - 4.1e-73 246.4 0.0 4.8e-73 246.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EPS33468.1 - 0.00058 18.9 0.0 0.0013 17.8 0.0 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 EPS33468.1 - 0.00092 18.4 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EPS33468.1 - 0.0035 15.6 0.0 0.0055 15.0 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme T_hemolysin PF12261.3 EPS33468.1 - 0.033 13.7 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 Thermostable hemolysin Aminotran_5 PF00266.14 EPS33468.1 - 0.048 12.3 0.0 0.16 10.6 0.0 1.8 1 1 0 1 1 1 0 Aminotransferase class-V zf-MYND PF01753.13 EPS33469.1 - 0.039 13.8 6.7 0.09 12.6 4.1 2.1 1 1 1 2 2 2 0 MYND finger zf-Mss51 PF13824.1 EPS33469.1 - 0.054 13.3 7.6 1.7 8.5 5.3 2.9 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Ald_Xan_dh_C2 PF02738.13 EPS33472.1 - 5.8e-199 661.9 0.4 8e-199 661.4 0.3 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 EPS33472.1 - 1.3e-49 167.9 0.0 2.4e-49 167.0 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.17 EPS33472.1 - 1.4e-33 115.2 0.0 3.1e-33 114.1 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.12 EPS33472.1 - 3.7e-33 113.5 0.4 1.5e-32 111.6 0.1 2.3 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.15 EPS33472.1 - 2.3e-28 97.8 0.0 5e-28 96.8 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 EPS33472.1 - 4.4e-08 32.7 2.3 5.2e-08 32.5 0.1 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain SEN1_N PF12726.2 EPS33474.1 - 0.098 10.6 0.0 0.11 10.5 0.0 1.0 1 0 0 1 1 1 0 SEN1 N terminal AMP-binding PF00501.23 EPS33475.1 - 5.3e-70 235.9 0.0 7.6e-70 235.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EPS33475.1 - 2.4e-66 223.2 0.0 4.4e-66 222.3 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EPS33475.1 - 1.5e-11 44.1 0.0 5.1e-11 42.4 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EPS33475.1 - 1.9e-10 40.8 0.0 4.1e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EPS33475.1 - 1.5e-08 35.4 0.0 5.3e-08 33.7 0.0 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 EPS33475.1 - 4.8e-06 25.4 0.0 2.9e-05 22.8 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EPS33475.1 - 0.00034 20.6 0.0 0.46 10.4 0.0 2.8 2 1 0 2 2 2 2 NADH(P)-binding Condensation PF00668.15 EPS33475.1 - 0.00091 18.1 0.1 0.0017 17.2 0.1 1.3 1 0 0 1 1 1 1 Condensation domain RmlD_sub_bind PF04321.12 EPS33475.1 - 0.016 14.1 0.0 0.24 10.2 0.0 2.4 2 0 0 2 2 2 0 RmlD substrate binding domain adh_short PF00106.20 EPS33475.1 - 0.13 12.1 1.9 0.74 9.7 0.0 2.9 4 0 0 4 4 4 0 short chain dehydrogenase Arylsulfotran_2 PF14269.1 EPS33477.1 - 1.2e-44 152.6 0.3 1.7e-44 152.1 0.2 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EPS33477.1 - 7.9e-09 34.5 1.1 9.9e-08 30.9 0.7 2.3 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) Beta_elim_lyase PF01212.16 EPS33478.1 - 1.2e-39 136.2 0.1 1.6e-39 135.7 0.1 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EPS33478.1 - 1.2e-07 30.9 0.0 1.8e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EPS33478.1 - 9.3e-05 21.3 0.0 0.00013 20.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_3 PF00202.16 EPS33478.1 - 0.00054 18.9 0.1 0.26 10.0 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-III Pyridoxal_deC PF00282.14 EPS33478.1 - 0.0032 15.9 0.0 0.0051 15.3 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Fungal_trans PF04082.13 EPS33479.1 - 2.6e-16 59.2 1.3 4.8e-16 58.4 0.9 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS33479.1 - 3.3e-06 26.9 8.8 6.4e-06 25.9 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UPRTase PF14681.1 EPS33480.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Oxidored_FMN PF00724.15 EPS33481.1 - 4.5e-79 265.9 0.0 7.4e-79 265.2 0.0 1.3 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1848 PF08902.6 EPS33481.1 - 0.21 11.0 0.0 0.33 10.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) Ham1p_like PF01725.11 EPS33482.1 - 1.9e-44 151.3 0.0 2.1e-44 151.1 0.0 1.0 1 0 0 1 1 1 1 Ham1 family Aldo_ket_red PF00248.16 EPS33483.1 - 2.1e-68 230.1 0.0 2.4e-68 230.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Mannosyl_trans2 PF04188.8 EPS33485.1 - 1.5e-59 202.0 15.7 1.8e-59 201.7 10.9 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) RPT PF13446.1 EPS33485.1 - 0.14 11.5 0.1 0.32 10.4 0.1 1.5 1 0 0 1 1 1 0 A repeated domain in UCH-protein DUF3437 PF11919.3 EPS33486.1 - 5.7e-32 109.2 0.0 1.6e-31 107.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) CLASP_N PF12348.3 EPS33486.1 - 3.5e-05 23.2 0.1 0.11 11.8 0.0 3.4 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.17 EPS33486.1 - 0.0023 17.8 0.0 1.9 8.7 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat Atg14 PF10186.4 EPS33486.1 - 0.42 9.5 0.5 0.76 8.6 0.3 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3405 PF11885.3 EPS33487.1 - 9.6e-173 574.9 1.7 1.5e-172 574.3 1.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) DUF1162 PF06650.7 EPS33488.1 - 4.3e-87 291.8 0.0 2.1e-85 286.3 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1162) Chorein_N PF12624.2 EPS33488.1 - 4.3e-42 142.3 0.1 1.4e-41 140.7 0.1 2.0 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EPS33488.1 - 2.5e-05 24.3 0.2 0.00022 21.2 0.0 2.5 2 0 0 2 2 2 1 ATG C terminal domain DUF3429 PF11911.3 EPS33489.1 - 7.8e-39 132.8 12.3 1e-38 132.4 8.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) APH PF01636.18 EPS33490.1 - 0.26 11.0 1.8 0.2 11.3 0.1 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family FGGY_C PF02782.11 EPS33492.1 - 1.5e-73 246.6 1.4 2.8e-73 245.7 0.7 1.7 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EPS33492.1 - 5.9e-61 205.8 0.0 7.8e-61 205.5 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 EPS33492.1 - 0.027 13.7 0.2 1.4 8.1 0.0 2.2 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Peptidase_M41 PF01434.13 EPS33493.1 - 4.5e-67 225.6 0.8 9.2e-67 224.6 0.6 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EPS33493.1 - 1.2e-43 148.4 0.0 4.3e-43 146.6 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EPS33493.1 - 2.7e-06 27.4 0.0 9.1e-06 25.7 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EPS33493.1 - 6e-06 26.0 0.0 1.9e-05 24.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EPS33493.1 - 1.5e-05 25.1 0.1 0.0033 17.5 0.1 3.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPS33493.1 - 1.7e-05 25.6 0.0 5.4e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EPS33493.1 - 4e-05 22.5 0.1 9.8e-05 21.2 0.0 1.6 2 0 0 2 2 2 1 TIP49 C-terminus RuvB_N PF05496.7 EPS33493.1 - 0.00029 19.9 0.0 0.00068 18.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EPS33493.1 - 0.0013 18.3 0.3 0.0045 16.7 0.2 1.9 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EPS33493.1 - 0.0019 17.6 0.0 0.0039 16.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 EPS33493.1 - 0.0021 17.9 0.0 0.006 16.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EPS33493.1 - 0.0069 15.8 4.7 0.074 12.4 0.2 3.2 2 1 1 3 3 3 1 AAA domain AAA_14 PF13173.1 EPS33493.1 - 0.0072 16.2 0.0 0.025 14.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_2 PF07724.9 EPS33493.1 - 0.014 15.2 0.0 0.057 13.3 0.0 2.1 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) NACHT PF05729.7 EPS33493.1 - 0.018 14.7 0.3 1.1 8.9 0.1 2.7 2 0 0 2 2 2 0 NACHT domain Mg_chelatase PF01078.16 EPS33493.1 - 0.019 14.1 0.2 0.039 13.1 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 EPS33493.1 - 0.019 14.9 0.8 0.042 13.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EPS33493.1 - 0.024 13.7 3.0 0.025 13.6 0.3 2.2 2 1 1 3 3 3 0 Zeta toxin DUF815 PF05673.8 EPS33493.1 - 0.029 13.3 0.0 0.062 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) KaiC PF06745.8 EPS33493.1 - 0.047 12.7 1.0 1.2 8.1 0.0 2.8 3 0 0 3 3 3 0 KaiC AAA_18 PF13238.1 EPS33493.1 - 0.058 13.7 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain NTP_transferase PF00483.18 EPS33496.1 - 6.1e-48 163.2 0.0 1.2e-47 162.3 0.0 1.5 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 EPS33496.1 - 3.7e-12 45.1 15.6 4.1e-10 38.7 3.7 4.4 2 1 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EPS33496.1 - 2.1e-10 40.9 0.0 3.4e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EPS33496.1 - 5.6e-07 28.9 7.8 3.9e-06 26.3 2.5 2.9 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase IspD PF01128.14 EPS33496.1 - 0.15 11.5 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase adh_short PF00106.20 EPS33497.1 - 3.1e-07 30.4 0.0 0.00011 22.1 0.0 2.8 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EPS33497.1 - 0.0013 18.4 0.0 0.0026 17.4 0.0 1.5 1 0 0 1 1 1 1 KR domain SynMuv_product PF06047.6 EPS33497.1 - 0.15 11.8 0.1 0.23 11.1 0.1 1.4 1 0 0 1 1 1 0 Ras-induced vulval development antagonist Suc_Fer-like PF06999.7 EPS33498.1 - 6.6e-37 127.7 0.0 9.7e-37 127.1 0.0 1.3 1 0 0 1 1 1 1 Sucrase/ferredoxin-like zf-H2C2_2 PF13465.1 EPS33500.1 - 2.2e-14 52.9 37.5 1.1e-06 28.5 0.5 5.5 5 1 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 EPS33500.1 - 6.4e-10 38.7 57.9 9.7e-05 22.4 3.4 5.1 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPS33500.1 - 0.0079 16.4 4.4 0.0079 16.4 3.0 5.8 5 1 0 5 5 5 4 C2H2-type zinc finger DUF605 PF04652.11 EPS33500.1 - 1.1 8.5 30.6 1.4 8.2 21.2 1.2 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 EPS33500.1 - 5.4 6.8 22.8 7.5 6.3 15.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Aminotran_1_2 PF00155.16 EPS33503.1 - 3e-36 125.1 0.0 4.1e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EPS33503.1 - 0.068 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase PH_10 PF15411.1 EPS33504.1 - 1.9e-38 131.1 0.0 3.7e-38 130.2 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.6 EPS33504.1 - 1.7e-33 114.4 0.0 3.2e-33 113.6 0.0 1.5 1 0 0 1 1 1 1 CDC24 Calponin RhoGEF PF00621.15 EPS33504.1 - 4.7e-29 101.5 0.7 7.9e-29 100.8 0.5 1.4 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.19 EPS33504.1 - 3.9e-07 29.6 0.1 9.2e-07 28.4 0.1 1.6 1 0 0 1 1 1 1 PB1 domain WD40 PF00400.27 EPS33505.1 - 2.4e-37 125.4 16.3 1.3e-06 27.9 0.0 7.8 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.2 EPS33505.1 - 1.1e-11 44.2 0.7 2.6e-11 43.0 0.5 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EPS33505.1 - 7.1e-07 28.7 0.2 1.8e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EPS33505.1 - 1.1e-06 27.1 2.7 0.0083 14.3 0.0 3.3 2 1 0 3 3 3 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EPS33505.1 - 0.015 15.0 0.1 3.7 7.3 0.0 3.8 1 1 2 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Uds1 PF15456.1 EPS33507.1 - 1e-44 151.4 1.2 1e-44 151.4 0.9 6.0 3 2 2 5 5 5 1 Up-regulated During Septation GAS PF13851.1 EPS33507.1 - 0.0048 16.1 9.4 0.0048 16.1 6.5 6.4 4 1 1 6 6 6 3 Growth-arrest specific micro-tubule binding DUF3584 PF12128.3 EPS33507.1 - 6.7 3.9 77.5 0.0028 15.0 38.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3584) MFS_1 PF07690.11 EPS33508.1 - 5.9e-26 91.0 37.9 9.1e-26 90.3 26.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EPS33508.1 - 0.085 12.6 2.7 0.21 11.3 0.2 2.5 2 0 0 2 2 2 0 MFS_1 like family UCR_hinge PF02320.11 EPS33509.1 - 2.6e-26 91.3 8.2 6.5e-26 90.0 5.7 1.7 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Vfa1 PF08432.5 EPS33509.1 - 0.077 13.0 15.3 0.098 12.6 10.6 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PRCC PF10253.4 EPS33509.1 - 0.19 12.3 11.0 0.25 12.0 7.7 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting CDC45 PF02724.9 EPS33509.1 - 0.2 9.6 14.3 0.2 9.6 9.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DHHW PF14286.1 EPS33509.1 - 0.25 10.6 9.4 0.29 10.3 6.5 1.1 1 0 0 1 1 1 0 DHHW protein Nop14 PF04147.7 EPS33509.1 - 0.45 8.3 24.4 0.51 8.1 16.9 1.1 1 0 0 1 1 1 0 Nop14-like family CT47 PF15623.1 EPS33509.1 - 0.51 10.0 33.3 0.63 9.7 23.1 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 DUF1510 PF07423.6 EPS33509.1 - 0.52 9.6 23.7 0.65 9.3 16.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CobT PF06213.7 EPS33509.1 - 0.54 9.3 23.5 0.68 9.0 16.3 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF2360 PF10152.4 EPS33509.1 - 0.82 9.9 10.2 1.3 9.3 7.0 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Ycf1 PF05758.7 EPS33509.1 - 1.2 6.7 13.2 1.2 6.7 9.1 1.0 1 0 0 1 1 1 0 Ycf1 CPSF100_C PF13299.1 EPS33509.1 - 1.2 9.2 6.5 2 8.5 4.5 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Merozoite_SPAM PF07133.6 EPS33509.1 - 1.4 8.7 32.2 2.2 8.1 22.3 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) GET2 PF08690.5 EPS33509.1 - 1.5 7.9 7.2 1.7 7.7 5.0 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 DUF4045 PF13254.1 EPS33509.1 - 1.8 7.7 14.4 2.1 7.5 9.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) RRN3 PF05327.6 EPS33509.1 - 2.2 6.3 11.0 2.2 6.2 7.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Zip PF02535.17 EPS33509.1 - 2.4 7.0 7.0 2.7 6.9 4.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DDHD PF02862.12 EPS33509.1 - 2.7 7.7 11.8 3.7 7.2 8.2 1.2 1 0 0 1 1 1 0 DDHD domain Raftlin PF15250.1 EPS33509.1 - 2.8 6.3 9.5 3.2 6.1 6.6 1.1 1 0 0 1 1 1 0 Raftlin SAPS PF04499.10 EPS33509.1 - 2.9 6.4 10.5 2.9 6.4 7.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.2 EPS33509.1 - 3.4 5.2 10.1 3.6 5.1 7.0 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein U79_P34 PF03064.11 EPS33509.1 - 4 6.8 10.9 5 6.5 7.5 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Mitofilin PF09731.4 EPS33509.1 - 4.9 5.6 19.2 5.9 5.4 13.3 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF2413 PF10310.4 EPS33509.1 - 5.8 5.6 19.0 7.4 5.2 13.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF913 PF06025.7 EPS33509.1 - 8.4 5.0 8.1 9.7 4.8 5.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) WWbp PF10349.4 EPS33510.1 - 7.3e-19 68.7 1.9 2.2e-18 67.2 0.3 2.0 2 0 0 2 2 2 1 WW-domain ligand protein Vps36_ESCRT-II PF11605.3 EPS33510.1 - 0.0017 18.1 0.0 0.013 15.2 0.0 2.0 2 0 0 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 PalH PF08733.5 EPS33511.1 - 0.27 10.0 10.5 0.3 9.8 7.3 1.1 1 0 0 1 1 1 0 PalH/RIM21 Acyltransferase PF01553.16 EPS33512.1 - 1e-08 34.6 0.0 0.00045 19.6 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase Prenyltransf PF01255.14 EPS33513.1 - 9.6e-80 266.8 0.0 1.8e-79 265.9 0.0 1.4 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Saccharop_dh PF03435.13 EPS33514.1 - 6.4e-132 440.1 0.0 7.5e-132 439.9 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EPS33514.1 - 5.9e-08 32.9 0.2 1e-07 32.0 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EPS33514.1 - 1.8e-06 28.0 0.7 3e-06 27.3 0.2 1.6 2 0 0 2 2 1 1 NADH(P)-binding TrkA_N PF02254.13 EPS33514.1 - 9e-05 22.4 0.4 0.00016 21.6 0.3 1.4 1 0 0 1 1 1 1 TrkA-N domain IlvN PF07991.7 EPS33514.1 - 0.00045 19.6 1.4 0.0011 18.3 0.1 2.2 3 0 0 3 3 3 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 EPS33514.1 - 0.0011 19.3 0.2 0.0025 18.2 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.14 EPS33514.1 - 0.0019 16.9 0.1 0.0026 16.4 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EPS33514.1 - 0.0023 17.2 0.4 0.0035 16.6 0.3 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_7 PF13241.1 EPS33514.1 - 0.0028 17.8 0.3 0.0057 16.8 0.2 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Semialdhyde_dh PF01118.19 EPS33514.1 - 0.014 15.6 0.2 0.025 14.8 0.1 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 EPS33514.1 - 0.033 14.6 0.1 0.061 13.8 0.1 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold 2-Hacid_dh_C PF02826.14 EPS33514.1 - 0.059 12.5 0.1 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 EPS33514.1 - 0.084 13.2 0.4 0.14 12.5 0.2 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.15 EPS33514.1 - 0.13 12.1 0.8 0.25 11.2 0.5 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF2325 PF10087.4 EPS33514.1 - 0.13 12.0 0.1 0.68 9.8 0.0 2.1 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) Aha1_N PF09229.6 EPS33515.1 - 8.5e-40 135.7 0.5 1.4e-39 135.0 0.3 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 EPS33515.1 - 2.2e-20 72.9 0.5 7.9e-20 71.2 0.2 1.9 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.4 EPS33515.1 - 3.7e-05 23.9 1.4 0.015 15.4 0.3 2.2 2 0 0 2 2 2 2 Polyketide cyclase / dehydrase and lipid transport Med18 PF09637.5 EPS33515.1 - 0.037 13.5 0.6 0.11 12.0 0.4 1.9 1 1 0 1 1 1 0 Med18 protein MARVEL PF01284.18 EPS33517.1 - 2.4e-12 46.8 14.6 3.1e-12 46.5 10.1 1.1 1 0 0 1 1 1 1 Membrane-associating domain PIG-U PF06728.8 EPS33517.1 - 0.016 14.0 5.5 0.021 13.6 3.8 1.2 1 0 0 1 1 1 0 GPI transamidase subunit PIG-U DUF4199 PF13858.1 EPS33517.1 - 0.043 13.7 0.6 0.043 13.7 0.4 2.6 2 2 0 3 3 3 0 Protein of unknown function (DUF4199) DUF3317 PF11779.3 EPS33517.1 - 2.4 7.6 6.7 18 4.8 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3317) FBPase PF00316.15 EPS33519.1 - 5.1e-118 393.5 0.0 6e-118 393.3 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase V_ATPase_I PF01496.14 EPS33520.1 - 1.9e-291 968.4 0.2 2.2e-291 968.2 0.1 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF1515 PF07439.6 EPS33520.1 - 0.0048 16.7 0.1 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1515) DivIC PF04977.10 EPS33520.1 - 0.067 12.6 0.3 0.31 10.5 0.2 2.2 1 0 0 1 1 1 0 Septum formation initiator DUF3552 PF12072.3 EPS33520.1 - 0.12 11.6 0.6 10 5.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) F-box PF00646.28 EPS33521.1 - 0.0089 15.6 0.0 0.028 14.0 0.0 1.9 1 0 0 1 1 1 1 F-box domain Inhibitor_I10 PF12559.3 EPS33521.1 - 0.084 13.1 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Serine endopeptidase inhibitors Acetyltransf_3 PF13302.1 EPS33522.1 - 1.8e-32 112.4 0.0 2.2e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPS33522.1 - 0.00058 19.8 0.1 0.0015 18.5 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EPS33522.1 - 0.0096 15.8 0.0 0.031 14.1 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain VPS9 PF02204.13 EPS33524.1 - 5.6e-31 106.6 0.0 1.4e-30 105.3 0.0 1.7 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 EPS33524.1 - 5.8e-10 38.4 0.4 9e-09 34.6 0.0 2.4 2 0 0 2 2 2 1 CUE domain DUF2310 PF10071.4 EPS33524.1 - 0.17 10.7 0.4 0.31 9.9 0.0 1.5 2 0 0 2 2 2 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) Asn_synthase PF00733.16 EPS33525.1 - 7.7e-52 176.3 0.0 1.8e-51 175.1 0.0 1.6 1 1 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EPS33525.1 - 3.1e-08 33.3 0.0 1.2e-07 31.4 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EPS33525.1 - 5e-06 26.5 0.0 1.4e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EPS33525.1 - 1.3e-05 24.4 0.0 2.3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Aluminium induced protein bZIP_1 PF00170.16 EPS33526.1 - 1.5e-06 28.0 6.1 2.6e-06 27.2 4.2 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EPS33526.1 - 4.5e-06 26.3 7.3 8.2e-06 25.5 5.0 1.4 1 0 0 1 1 1 1 Basic region leucine zipper IncA PF04156.9 EPS33526.1 - 0.024 14.2 1.9 0.044 13.3 1.3 1.3 1 0 0 1 1 1 0 IncA protein Sec2p PF06428.6 EPS33526.1 - 0.045 13.6 3.0 0.092 12.6 2.1 1.5 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p HTH_Tnp_Tc5 PF03221.11 EPS33526.1 - 0.055 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain bZIP_Maf PF03131.12 EPS33526.1 - 2.1 8.6 8.0 4.9 7.5 5.5 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF3275 PF11679.3 EPS33526.1 - 3.7 7.1 5.3 9.4 5.7 3.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) PH_6 PF15406.1 EPS33528.1 - 9e-37 125.5 2.1 9e-37 125.5 1.4 2.9 3 1 0 3 3 3 1 Pleckstrin homology domain PH PF00169.24 EPS33528.1 - 8.7e-05 22.6 0.1 0.00029 20.9 0.0 1.9 2 0 0 2 2 2 1 PH domain DUF4598 PF15370.1 EPS33528.1 - 3.2 8.0 14.9 0.13 12.5 2.8 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4598) DUF2786 PF10979.3 EPS33531.1 - 0.14 11.8 0.4 0.23 11.2 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2786) Ank_2 PF12796.2 EPS33532.1 - 7.7e-81 266.5 0.1 5.1e-14 52.3 0.1 6.6 5 2 1 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EPS33532.1 - 5.3e-55 180.6 16.7 7.6e-06 25.4 0.0 15.1 16 0 0 16 16 16 12 Ankyrin repeat Ank_5 PF13857.1 EPS33532.1 - 5e-44 147.3 13.4 5.4e-07 29.6 0.0 10.6 7 3 3 10 10 10 9 Ankyrin repeats (many copies) Ank_4 PF13637.1 EPS33532.1 - 2.7e-43 145.6 9.0 3.4e-08 33.7 0.1 12.2 5 4 7 13 13 13 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPS33532.1 - 1.1e-34 114.9 7.0 0.00016 21.5 0.0 14.2 15 0 0 15 15 15 7 Ankyrin repeat DAO PF01266.19 EPS33533.1 - 8.2e-64 215.7 0.1 1.1e-63 215.3 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T PF01571.16 EPS33533.1 - 2.1e-56 190.6 0.0 6.9e-56 188.9 0.0 1.9 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EPS33533.1 - 2.3e-16 59.5 0.0 5.3e-16 58.4 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.7 EPS33533.1 - 3.2e-05 23.8 0.0 0.00039 20.3 0.0 2.7 4 0 0 4 4 4 1 Sarcosine oxidase, gamma subunit family Pyr_redox_3 PF13738.1 EPS33533.1 - 6.8e-05 23.0 0.0 0.00014 21.9 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 EPS33533.1 - 0.0005 19.8 0.1 0.0014 18.4 0.0 1.7 1 0 0 1 1 1 1 ThiF family Pyr_redox PF00070.22 EPS33533.1 - 0.00052 20.3 0.9 0.0052 17.1 0.0 2.6 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EPS33533.1 - 0.0015 18.5 0.5 0.0099 15.8 0.1 2.4 3 0 0 3 3 3 1 TrkA-N domain Pyr_redox_2 PF07992.9 EPS33533.1 - 0.0037 17.1 0.1 0.015 15.1 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EPS33533.1 - 0.017 15.1 0.1 0.038 14.0 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 EPS33533.1 - 0.035 14.1 0.0 0.15 12.1 0.0 2.2 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EPS33533.1 - 0.045 13.5 0.0 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EPS33533.1 - 0.12 10.9 0.1 1.4 7.4 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Saccharop_dh PF03435.13 EPS33533.1 - 0.19 10.6 0.4 2 7.3 0.2 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase Sulfate_transp PF00916.15 EPS33534.1 - 1.5e-40 138.9 8.7 1.5e-40 138.9 6.1 1.6 2 0 0 2 2 2 1 Sulfate transporter family cNMP_binding PF00027.24 EPS33534.1 - 3.4e-15 55.6 0.0 7.1e-15 54.5 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 EPS33534.1 - 3.5e-10 39.3 0.0 7.2e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 STAS domain Sld5 PF05916.6 EPS33536.1 - 2.2e-12 47.2 0.0 3.4e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 GINS complex protein DUF3016 PF11454.3 EPS33536.1 - 0.12 12.0 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3016) Rcd1 PF04078.8 EPS33539.1 - 4.2e-131 435.5 2.8 5.4e-131 435.1 1.9 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like FRQ PF09421.5 EPS33539.1 - 0.01 13.6 1.2 0.012 13.4 0.9 1.0 1 0 0 1 1 1 0 Frequency clock protein TFIIA PF03153.8 EPS33539.1 - 0.21 11.4 14.5 0.27 11.0 10.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ThylakoidFormat PF11264.3 EPS33539.1 - 0.61 9.6 6.3 11 5.6 4.6 2.3 2 0 0 2 2 2 0 Thylakoid formation protein PAT1 PF09770.4 EPS33539.1 - 3.4 5.7 28.4 4.3 5.4 19.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PHD PF00628.24 EPS33540.1 - 4.8e-08 32.5 9.9 4.8e-08 32.5 6.9 1.9 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 EPS33540.1 - 0.0014 17.8 4.7 0.0014 17.8 3.2 2.0 2 0 0 2 2 2 1 PHD-finger HMG_box PF00505.14 EPS33544.1 - 1.3e-13 51.0 0.0 5.3e-13 49.0 0.0 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box Prefoldin_2 PF01920.15 EPS33545.1 - 6.2e-19 67.7 1.3 7.7e-19 67.4 0.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit Microvir_H PF04687.7 EPS33545.1 - 0.046 12.7 0.5 0.054 12.5 0.3 1.1 1 0 0 1 1 1 0 Microvirus H protein (pilot protein) ADIP PF11559.3 EPS33545.1 - 1.5 8.6 7.8 2.7 7.8 0.7 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Mito_carr PF00153.22 EPS33549.1 - 4.1e-55 183.4 3.7 9.6e-19 66.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ceramidase PF05875.7 EPS33550.1 - 3.1e-110 367.4 12.3 3.6e-110 367.2 8.6 1.0 1 0 0 1 1 1 1 Ceramidase Abhydrolase_6 PF12697.2 EPS33551.1 - 1.8e-27 96.7 0.3 4.5e-27 95.4 0.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPS33551.1 - 3.8e-05 23.4 0.0 5.8e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPS33551.1 - 0.00035 20.1 0.0 0.00067 19.2 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.8 EPS33551.1 - 0.082 12.4 0.1 0.19 11.2 0.1 1.5 2 0 0 2 2 2 0 PGAP1-like protein TFIID_20kDa PF03847.8 EPS33552.1 - 0.14 12.4 0.0 1.1 9.6 0.0 2.0 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A PTCB-BRCT PF12738.2 EPS33553.1 - 9.6e-33 111.8 4.4 5.8e-20 70.9 0.2 5.3 5 0 0 5 5 5 4 twin BRCT domain BRCT PF00533.21 EPS33553.1 - 2e-31 107.9 0.0 2.9e-08 33.7 0.0 6.3 6 0 0 6 6 6 5 BRCA1 C Terminus (BRCT) domain ESCRT-II PF05871.7 EPS33554.1 - 1e-53 181.0 0.0 1.4e-53 180.4 0.0 1.2 1 0 0 1 1 1 1 ESCRT-II complex subunit Methyltransf_4 PF02390.12 EPS33555.1 - 8.2e-46 155.5 0.0 2.6e-33 114.7 0.0 2.1 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 EPS33555.1 - 0.00083 19.9 0.0 0.0015 19.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPS33555.1 - 0.00088 19.2 0.0 0.0023 17.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPS33555.1 - 0.0027 18.1 0.0 0.0085 16.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EPS33555.1 - 0.0093 15.3 0.0 0.12 11.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EPS33555.1 - 0.01 16.1 0.0 0.064 13.6 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 EPS33555.1 - 0.025 15.0 0.0 1.1 9.8 0.0 2.9 3 0 0 3 3 3 0 Methyltransferase domain FmrO PF07091.6 EPS33555.1 - 0.043 12.7 0.4 0.071 12.0 0.0 1.5 2 0 0 2 2 2 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_31 PF13847.1 EPS33555.1 - 0.054 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EPS33555.1 - 0.083 12.5 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain LIM PF00412.17 EPS33556.1 - 2.3e-27 94.8 22.1 2.6e-10 40.1 2.1 3.7 3 1 0 3 3 3 3 LIM domain Zn_ribbon_recom PF13408.1 EPS33556.1 - 0.22 11.7 0.1 0.22 11.7 0.1 3.0 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain MFS_1 PF07690.11 EPS33557.1 - 1.5e-22 79.7 48.6 1e-21 77.0 34.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily RNB PF00773.14 EPS33558.1 - 2.7e-96 322.6 0.0 4.6e-96 321.9 0.0 1.4 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 EPS33558.1 - 9.7e-10 38.6 0.2 2.6e-09 37.2 0.1 1.8 1 0 0 1 1 1 1 PIN domain CN_hydrolase PF00795.17 EPS33559.1 - 2.9e-28 98.4 0.0 4.5e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase ESSS PF10183.4 EPS33560.1 - 4.3e-30 104.2 0.1 5e-30 103.9 0.0 1.0 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Dna2 PF08696.6 EPS33561.1 - 4.3e-70 235.2 1.1 9.2e-70 234.1 0.8 1.5 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.1 EPS33561.1 - 2.6e-52 177.1 0.0 4.3e-52 176.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EPS33561.1 - 4.4e-41 141.0 0.2 3.5e-20 72.6 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.1 EPS33561.1 - 1.1e-14 54.4 0.0 2.4e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPS33561.1 - 9.4e-12 44.5 0.6 3.4e-11 42.7 0.2 2.2 2 0 0 2 2 2 1 Part of AAA domain PDDEXK_1 PF12705.2 EPS33561.1 - 3.6e-11 42.9 0.1 9.5e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.12 EPS33561.1 - 1.1e-08 35.1 0.1 2.2e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF83 Viral_helicase1 PF01443.13 EPS33561.1 - 3.3e-06 26.8 2.0 0.39 10.1 0.0 3.6 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 EPS33561.1 - 7e-05 22.5 0.0 0.00034 20.2 0.0 2.2 2 0 0 2 2 2 1 Helicase UvrD-helicase PF00580.16 EPS33561.1 - 0.00023 20.5 0.1 0.00023 20.5 0.1 2.7 4 0 0 4 4 3 1 UvrD/REP helicase N-terminal domain AAA_16 PF13191.1 EPS33561.1 - 0.00056 19.9 0.0 0.0082 16.1 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain CbiA PF01656.18 EPS33561.1 - 0.00057 19.3 0.0 0.0015 17.9 0.0 1.7 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54 PF00448.17 EPS33561.1 - 0.00065 19.1 0.0 0.0015 17.9 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain DUF911 PF06023.7 EPS33561.1 - 0.00071 18.8 0.1 0.0015 17.7 0.1 1.5 1 0 0 1 1 1 1 Archaeal protein of unknown function (DUF911) MobB PF03205.9 EPS33561.1 - 0.0017 18.1 0.0 0.004 16.8 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B PIF1 PF05970.9 EPS33561.1 - 0.0081 15.1 0.2 0.04 12.8 0.2 2.0 1 1 0 1 1 1 1 PIF1-like helicase RE_ScaI PF09569.5 EPS33561.1 - 0.0083 15.6 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 ScaI restriction endonuclease DUF2075 PF09848.4 EPS33561.1 - 0.022 13.7 0.0 0.04 12.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 EPS33561.1 - 0.023 14.1 0.0 0.07 12.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EPS33561.1 - 0.032 13.1 0.1 0.064 12.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.1 EPS33561.1 - 0.032 14.3 0.1 0.23 11.6 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EPS33561.1 - 0.044 13.2 0.0 0.14 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA-like domain DUF87 PF01935.12 EPS33561.1 - 0.057 13.2 1.2 0.15 11.8 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF87 ArgK PF03308.11 EPS33561.1 - 0.07 11.8 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 ArgK protein ResIII PF04851.10 EPS33561.1 - 0.074 12.8 0.2 0.21 11.3 0.1 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DUF1507 PF07408.6 EPS33561.1 - 0.11 12.2 0.0 0.43 10.3 0.0 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF1507) NTPase_1 PF03266.10 EPS33561.1 - 0.23 11.1 1.9 0.49 10.0 0.1 2.4 3 0 0 3 3 3 0 NTPase Ribonuc_P_40 PF08584.6 EPS33562.1 - 6.9e-79 264.8 0.0 9.9e-79 264.2 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit WD40 PF00400.27 EPS33563.1 - 4.3e-34 115.1 11.9 8.6e-10 38.1 0.0 7.3 7 0 0 7 7 7 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EPS33563.1 - 1.3e-08 33.5 0.0 4.1e-06 25.3 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.6 EPS33563.1 - 8.1e-06 25.6 0.0 0.069 12.8 0.0 3.1 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 EPS33563.1 - 0.0029 17.0 0.0 0.044 13.2 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.3 EPS33563.1 - 0.0039 15.4 0.4 0.1 10.7 0.1 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 TFIIIC_delta PF12657.2 EPS33563.1 - 0.38 10.4 4.9 0.36 10.5 0.3 3.0 4 1 1 5 5 5 0 Transcription factor IIIC subunit delta N-term Fungal_trans PF04082.13 EPS33564.1 - 1e-22 80.2 0.1 1.7e-22 79.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS33564.1 - 2.1e-09 37.0 9.7 4.3e-09 36.1 6.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF655 PF04919.7 EPS33564.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF655) Ribosomal_L2_C PF03947.13 EPS33565.1 - 7.1e-45 151.9 6.8 2.5e-32 111.4 0.3 2.9 2 1 1 3 3 3 2 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EPS33565.1 - 2.9e-26 91.2 0.1 5e-26 90.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Cyclin_N PF00134.18 EPS33566.1 - 5.1e-46 155.3 0.1 6.7e-45 151.7 0.1 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EPS33566.1 - 1e-34 119.0 0.1 1.8e-34 118.1 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain HIT PF01230.18 EPS33567.1 - 2e-18 66.7 0.1 4.3e-18 65.6 0.0 1.5 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 EPS33567.1 - 4e-07 30.2 0.0 6.1e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EPS33567.1 - 8.1e-05 22.2 0.6 0.00032 20.3 0.0 2.2 2 1 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 Methyltransf_26 PF13659.1 EPS33568.1 - 3.4e-11 43.2 0.0 8e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EPS33568.1 - 4.1e-11 42.7 0.0 6.8e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.11 EPS33568.1 - 0.012 14.6 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 N-6 DNA Methylase N6_N4_Mtase PF01555.13 EPS33568.1 - 0.04 13.4 0.0 0.31 10.4 0.0 2.2 2 0 0 2 2 2 0 DNA methylase SIR2 PF02146.12 EPS33569.1 - 1.2e-59 201.0 0.0 1.9e-59 200.3 0.0 1.3 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 EPS33569.1 - 0.057 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 EPS33569.1 - 0.084 12.6 0.1 9.5 5.9 0.0 2.5 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain TPR_11 PF13414.1 EPS33570.1 - 5.4e-10 38.7 3.6 1e-05 25.0 0.1 4.0 3 1 1 4 4 4 2 TPR repeat TPR_16 PF13432.1 EPS33570.1 - 5.5e-09 36.4 6.5 0.00035 21.1 0.3 3.6 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EPS33570.1 - 2.8e-08 33.9 11.1 0.00042 20.6 0.4 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EPS33570.1 - 4.3e-08 32.9 5.3 8.5e-05 22.4 0.7 3.9 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EPS33570.1 - 1.9e-07 30.3 0.4 0.00072 19.1 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EPS33570.1 - 9.4e-06 25.8 7.7 0.74 10.6 1.0 5.4 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 EPS33570.1 - 2.4e-05 23.9 12.0 0.0055 16.5 0.0 5.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.23 EPS33570.1 - 9.7e-05 21.8 3.7 0.044 13.4 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 EPS33570.1 - 0.00038 20.2 4.4 0.33 10.8 0.1 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EPS33570.1 - 0.00055 19.9 1.8 15 6.0 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Apc3 PF12895.2 EPS33570.1 - 0.0027 17.7 1.8 4.5 7.4 0.0 3.2 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 HEAT_2 PF13646.1 EPS33570.1 - 0.0038 17.4 7.0 0.7 10.2 0.1 3.5 3 1 0 3 3 3 2 HEAT repeats TPR_7 PF13176.1 EPS33570.1 - 0.38 10.6 6.0 1.1 9.1 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EPS33570.1 - 1.3 9.6 8.2 1.7e+02 3.0 0.0 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat RWD PF05773.17 EPS33571.1 - 4.6e-22 78.0 0.4 4.6e-22 78.0 0.3 1.7 2 0 0 2 2 2 1 RWD domain Phage_integrase PF00589.17 EPS33571.1 - 0.023 14.3 0.6 0.033 13.8 0.4 1.2 1 0 0 1 1 1 0 Phage integrase family DDHD PF02862.12 EPS33571.1 - 0.03 14.1 2.5 0.039 13.7 1.7 1.1 1 0 0 1 1 1 0 DDHD domain AAA_23 PF13476.1 EPS33571.1 - 0.099 12.9 6.6 0.11 12.7 4.6 1.3 1 0 0 1 1 1 0 AAA domain VitK2_biosynth PF02621.9 EPS33571.1 - 0.16 11.1 1.6 0.23 10.6 1.1 1.2 1 0 0 1 1 1 0 Menaquinone biosynthesis Med5 PF08689.5 EPS33571.1 - 8.9 3.8 8.9 18 2.8 6.2 1.2 1 1 0 1 1 1 0 Mediator complex subunit Med5 Sec8_exocyst PF04048.9 EPS33572.1 - 0.52 9.9 3.4 9.1 5.9 0.4 2.4 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain UQ_con PF00179.21 EPS33573.1 - 1.8e-17 63.0 0.0 2.1e-17 62.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EPS33573.1 - 0.043 13.6 0.0 0.043 13.6 0.0 1.2 1 0 0 1 1 1 0 RWD domain Sec7_N PF12783.2 EPS33574.1 - 2.5e-39 134.4 7.4 3.7e-39 133.8 0.3 3.7 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EPS33574.1 - 0.0017 17.8 0.6 0.062 12.8 0.0 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) Ipi1_N PF12333.3 EPS33574.1 - 0.0037 17.1 5.1 0.13 12.2 0.1 4.0 5 0 0 5 5 5 2 Rix1 complex component involved in 60S ribosome maturation Vps26 PF03643.10 EPS33575.1 - 1.4e-129 430.7 0.2 1.8e-129 430.4 0.1 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 EPS33575.1 - 0.00067 19.4 0.5 1.1 9.0 0.0 3.1 4 0 0 4 4 4 2 Arrestin (or S-antigen), N-terminal domain SKI PF01202.17 EPS33576.1 - 2.9e-14 53.2 0.0 4e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.1 EPS33576.1 - 6.8e-11 42.2 0.0 9.3e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPS33576.1 - 1.1e-08 35.4 0.0 1.9e-08 34.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPS33576.1 - 1.2e-08 35.8 0.0 1.5e-08 35.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EPS33576.1 - 0.00096 17.9 0.0 0.0016 17.1 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein RNA_helicase PF00910.17 EPS33576.1 - 0.015 15.4 0.0 0.067 13.3 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.1 EPS33576.1 - 0.016 15.1 0.0 0.036 14.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EPS33576.1 - 0.021 15.0 0.0 0.045 13.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPS33576.1 - 0.037 14.1 0.0 0.1 12.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain Cytidylate_kin2 PF13189.1 EPS33576.1 - 0.045 13.6 0.0 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 Cytidylate kinase-like family CoaE PF01121.15 EPS33576.1 - 0.067 12.5 0.1 0.18 11.2 0.0 1.6 2 0 0 2 2 2 0 Dephospho-CoA kinase DUF258 PF03193.11 EPS33576.1 - 0.079 12.1 0.0 0.092 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 KTI12 PF08433.5 EPS33576.1 - 0.082 12.1 1.2 3.5 6.7 0.1 2.6 3 0 0 3 3 3 0 Chromatin associated protein KTI12 AAA_16 PF13191.1 EPS33576.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 EPS33576.1 - 0.15 12.3 0.2 0.59 10.4 0.0 1.9 2 0 0 2 2 2 0 ABC transporter 2-oxoacid_dh PF00198.18 EPS33577.1 - 4.1e-80 268.3 0.1 6.3e-80 267.7 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EPS33577.1 - 8e-14 51.0 0.0 1.6e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EPS33577.1 - 3.6e-12 45.7 0.1 6.7e-12 44.8 0.1 1.5 1 0 0 1 1 1 1 e3 binding domain DUF3510 PF12022.3 EPS33577.1 - 0.12 12.5 1.4 0.35 10.9 0.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) DUF2823 PF11034.3 EPS33578.1 - 9.4e-32 108.9 14.1 1e-31 108.8 9.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) KGG PF10685.4 EPS33579.1 - 2e-25 88.1 22.1 7.9e-12 44.7 2.9 3.1 3 0 0 3 3 3 3 Stress-induced bacterial acidophilic repeat motif VanY PF02557.12 EPS33579.1 - 0.04 13.7 0.2 0.04 13.7 0.1 1.2 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Phostensin_N PF13916.1 EPS33579.1 - 1.5 8.8 5.3 3.3 7.7 0.5 2.5 1 1 2 3 3 3 0 PP1-regulatory protein, Phostensin N-terminal CHZ PF09649.5 EPS33580.1 - 0.06 12.5 0.2 0.12 11.6 0.1 1.4 1 0 0 1 1 1 0 Histone chaperone domain CHZ AAA PF00004.24 EPS33581.1 - 1e-14 54.8 0.0 1.8e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EPS33581.1 - 1.8e-05 24.4 0.0 3.3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EPS33581.1 - 2.5e-05 24.4 0.0 7.1e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPS33581.1 - 0.00016 22.4 0.0 0.00044 21.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPS33581.1 - 0.00029 20.5 0.0 0.001 18.7 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EPS33581.1 - 0.00075 19.5 0.1 0.003 17.5 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.16 EPS33581.1 - 0.019 14.1 0.1 0.037 13.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EPS33581.1 - 0.02 15.1 0.0 0.05 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EPS33581.1 - 0.04 13.3 0.0 0.093 12.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.1 EPS33581.1 - 0.07 12.6 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EPS33581.1 - 0.072 12.9 0.0 0.19 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EPS33581.1 - 0.084 11.9 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 EPS33581.1 - 0.12 11.7 0.1 0.33 10.3 0.1 1.7 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 EPS33581.1 - 0.19 10.8 0.0 0.77 8.8 0.0 1.9 2 0 0 2 2 2 0 KaiC TIP49 PF06068.8 EPS33581.1 - 0.21 10.2 0.0 0.32 9.6 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus PI-PLC-X PF00388.14 EPS33582.1 - 4.7e-11 42.2 0.0 8e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Ribosomal_L10 PF00466.15 EPS33583.1 - 0.039 13.8 0.0 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein L10 Glycos_transf_3 PF00591.16 EPS33584.1 - 8.2e-56 189.2 0.0 1.6e-46 158.7 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 EPS33584.1 - 1.7e-06 27.5 0.2 3.8e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain DNA_RNApol_7kD PF03604.8 EPS33585.1 - 7.9e-15 54.0 7.0 1e-14 53.7 4.9 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DUF2197 PF09963.4 EPS33585.1 - 0.00028 20.7 1.5 0.032 14.1 0.0 2.1 1 1 1 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2197) HypA PF01155.14 EPS33585.1 - 0.00032 20.3 0.2 0.00032 20.3 0.1 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EPS33585.1 - 0.0022 17.7 0.3 0.003 17.3 0.2 1.2 1 0 0 1 1 1 1 Double zinc ribbon GFA PF04828.9 EPS33585.1 - 0.0092 15.9 1.3 1.9 8.4 0.1 2.1 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme DUF2757 PF10955.3 EPS33585.1 - 0.029 14.5 0.4 0.037 14.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) DUF2296 PF10058.4 EPS33585.1 - 0.042 13.5 0.3 0.39 10.5 0.0 2.1 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Zn_Tnp_IS1595 PF12760.2 EPS33585.1 - 0.11 12.2 5.8 0.33 10.7 4.0 1.7 1 1 1 2 2 2 0 Transposase zinc-ribbon domain DUF2248 PF10005.4 EPS33585.1 - 0.11 11.3 0.3 0.13 11.1 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2248) DUF2082 PF09855.4 EPS33585.1 - 0.11 12.3 1.2 0.13 12.1 0.1 1.6 1 1 0 1 1 1 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) zf-RING_UBOX PF13445.1 EPS33585.1 - 0.12 12.0 2.0 1 9.1 0.2 2.2 1 1 1 2 2 2 0 RING-type zinc-finger Ogr_Delta PF04606.7 EPS33585.1 - 0.15 11.7 3.0 6.4 6.5 0.3 2.2 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger A2L_zn_ribbon PF08792.5 EPS33585.1 - 0.17 11.3 1.7 0.6 9.6 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain DUF35_N PF12172.3 EPS33585.1 - 0.27 11.2 2.1 4.1 7.4 0.1 2.3 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) RRN7 PF11781.3 EPS33585.1 - 0.33 10.4 3.3 7.6 6.1 0.3 2.3 1 1 1 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 DUF951 PF06107.6 EPS33585.1 - 0.57 9.7 3.8 1.6 8.3 0.4 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF951) TF_Zn_Ribbon PF08271.7 EPS33585.1 - 0.62 9.4 2.8 7.6 5.9 0.3 2.0 1 1 2 3 3 3 0 TFIIB zinc-binding zf-NADH-PPase PF09297.6 EPS33585.1 - 0.9 9.1 4.5 2.3 7.8 3.1 1.7 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain TFIIS_C PF01096.13 EPS33585.1 - 1.1 8.9 4.2 4.1 7.1 0.4 2.3 1 1 2 3 3 3 0 Transcription factor S-II (TFIIS) Zn_ribbon_recom PF13408.1 EPS33585.1 - 1.4 9.2 7.3 1 9.6 0.7 2.2 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain UPF0547 PF10571.4 EPS33585.1 - 1.6 8.5 4.1 5.3 6.8 1.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Ribosomal_L37e PF01907.14 EPS33585.1 - 6.8 6.5 7.0 2.3 8.0 2.6 2.0 2 1 1 3 3 3 0 Ribosomal protein L37e Fe_hyd_lg_C PF02906.9 EPS33586.1 - 1e-62 212.0 0.0 1.9e-62 211.0 0.0 1.5 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain DUF2263 PF10021.4 EPS33587.1 - 2.1e-17 63.4 0.0 7.3e-17 61.7 0.0 1.9 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.16 EPS33587.1 - 0.06 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Macro domain Fapy_DNA_glyco PF01149.19 EPS33588.1 - 1.4e-25 89.9 0.0 2.4e-25 89.1 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.9 EPS33588.1 - 3.7e-21 74.6 0.0 6.5e-21 73.8 0.0 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain FbpA PF05833.6 EPS33588.1 - 0.00028 19.5 0.1 0.00062 18.4 0.0 1.6 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) Cid2 PF09774.4 EPS33589.1 - 2.9e-51 173.5 0.1 3.4e-51 173.3 0.1 1.1 1 0 0 1 1 1 1 Caffeine-induced death protein 2 NARP1 PF12569.3 EPS33590.1 - 2e-213 709.8 22.5 1.4e-210 700.4 12.6 2.3 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 TPR_11 PF13414.1 EPS33590.1 - 5.8e-22 77.1 27.8 8.3e-07 28.5 0.3 8.6 6 3 3 9 9 9 6 TPR repeat TPR_16 PF13432.1 EPS33590.1 - 1.3e-18 67.1 23.9 0.00086 19.9 0.8 10.0 9 1 1 10 10 9 3 Tetratricopeptide repeat TPR_2 PF07719.12 EPS33590.1 - 7.3e-18 62.9 29.7 7.1e-05 22.4 0.3 11.4 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_19 PF14559.1 EPS33590.1 - 9.9e-18 64.2 27.6 0.0057 16.9 0.3 8.4 6 3 2 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.1 EPS33590.1 - 1.7e-15 56.0 26.3 0.0082 16.6 0.2 12.3 9 3 6 15 15 13 4 Tetratricopeptide repeat TPR_12 PF13424.1 EPS33590.1 - 6.5e-13 48.4 21.5 0.007 16.2 0.1 7.9 7 1 1 8 8 7 5 Tetratricopeptide repeat TPR_1 PF00515.23 EPS33590.1 - 1.3e-11 43.5 23.1 1.2e-05 24.6 0.3 9.5 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.1 EPS33590.1 - 9.1e-10 37.9 6.5 3.4 8.0 0.1 8.2 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_9 PF13371.1 EPS33590.1 - 9e-07 28.6 12.0 0.00022 20.9 1.4 6.0 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_8 PF13181.1 EPS33590.1 - 2e-05 24.0 20.9 0.0012 18.4 0.1 8.1 9 0 0 9 9 8 1 Tetratricopeptide repeat Apc3 PF12895.2 EPS33590.1 - 0.00013 22.0 21.7 0.045 13.8 0.7 6.6 5 3 3 8 8 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EPS33590.1 - 0.00015 21.3 11.4 0.46 10.3 0.1 6.7 6 1 0 7 7 6 1 Tetratricopeptide repeat TPR_3 PF07720.7 EPS33590.1 - 0.00051 19.7 0.1 0.095 12.5 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_4 PF07721.9 EPS33590.1 - 0.00065 19.8 1.7 0.4 11.2 0.1 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EPS33590.1 - 0.002 18.4 19.4 0.94 10.0 0.2 7.8 9 0 0 9 9 6 2 Tetratricopeptide repeat BTAD PF03704.12 EPS33590.1 - 0.011 16.0 0.1 0.011 16.0 0.1 3.3 3 0 0 3 3 3 0 Bacterial transcriptional activator domain Tim54 PF11711.3 EPS33591.1 - 6.1e-145 482.6 0.1 7.1e-145 482.3 0.1 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Pkinase PF00069.20 EPS33592.1 - 4.8e-54 183.2 2.1 1e-37 129.7 0.1 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EPS33592.1 - 1.6e-24 86.3 0.4 2.8e-19 69.1 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 EPS33592.1 - 0.00012 21.2 0.1 0.00038 19.5 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EPS33592.1 - 0.00013 21.0 0.0 0.00013 21.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EPS33592.1 - 0.0038 17.0 0.0 0.0038 17.0 0.0 2.9 2 2 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EPS33592.1 - 0.0065 15.3 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_C PF00433.19 EPS33592.1 - 0.0091 16.5 0.0 0.025 15.0 0.0 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain BAF1_ABF1 PF04684.8 EPS33592.1 - 0.51 9.1 11.3 0.8 8.4 7.9 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor TFIIA PF03153.8 EPS33592.1 - 7.9 6.2 16.5 12 5.6 11.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-met PF12874.2 EPS33593.1 - 6.9e-06 26.0 1.0 1.4e-05 25.1 0.7 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PRP4 PF08799.6 EPS33593.1 - 0.048 12.9 0.9 0.093 12.0 0.6 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like Peptidase_A21 PF03566.8 EPS33593.1 - 0.16 10.0 0.1 0.2 9.7 0.1 1.1 1 0 0 1 1 1 0 Peptidase family A21 CAP_GLY PF01302.20 EPS33594.1 - 3.5e-19 68.2 0.1 5.9e-19 67.5 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 EPS33594.1 - 8.7e-16 57.1 8.8 0.00078 19.0 0.2 5.3 3 2 3 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPS33594.1 - 1.9e-13 49.9 1.0 3.4e-05 23.5 0.0 3.9 3 1 1 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 EPS33594.1 - 6.7e-09 34.5 2.8 1.7 8.9 0.0 6.7 4 3 1 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.1 EPS33594.1 - 1.6e-07 30.6 4.1 1.6 9.0 0.4 6.9 7 0 0 7 7 7 1 Leucine Rich repeat LRR_7 PF13504.1 EPS33594.1 - 7.3e-07 28.3 0.5 24 5.7 0.0 7.1 7 0 0 7 7 7 0 Leucine rich repeat LRR_9 PF14580.1 EPS33594.1 - 0.077 12.5 0.2 1.2 8.6 0.0 2.6 2 1 1 3 3 3 0 Leucine-rich repeat PDE8 PF08629.5 EPS33595.1 - 0.089 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 PDE8 phosphodiesterase Zn_clus PF00172.13 EPS33596.1 - 1.9e-08 34.0 8.6 3.3e-08 33.3 6.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-U1 PF06220.7 EPS33597.1 - 8.1e-06 25.2 0.1 1.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 U1 zinc finger CCDC84 PF14968.1 EPS33597.1 - 0.0015 18.0 0.2 0.0016 17.9 0.1 1.2 1 0 0 1 1 1 1 Coiled coil protein 84 Phage_lysis PF03245.8 EPS33597.1 - 0.0065 16.4 1.0 0.018 15.0 0.7 1.7 1 0 0 1 1 1 1 Bacteriophage Rz lysis protein 2-Hacid_dh_C PF02826.14 EPS33598.1 - 1.4e-58 196.9 0.0 1.8e-58 196.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EPS33598.1 - 5.1e-15 55.1 0.0 6.6e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EPS33598.1 - 2.4e-05 24.2 0.2 3.8e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EPS33598.1 - 0.006 15.9 0.0 0.0098 15.2 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain AdoHcyase_NAD PF00670.16 EPS33598.1 - 0.054 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Clavanin PF05452.6 EPS33599.1 - 0.13 12.2 0.2 1.3 9.0 0.0 2.2 2 0 0 2 2 2 0 Clavanin APH PF01636.18 EPS33599.1 - 0.39 10.4 2.4 0.28 10.8 0.6 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family CwfJ_C_1 PF04677.10 EPS33600.1 - 3.1e-30 104.3 0.0 8.1e-30 102.9 0.0 1.7 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EPS33600.1 - 7.8e-24 84.0 0.0 2.5e-23 82.3 0.0 2.0 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 DUF1777 PF08648.7 EPS33600.1 - 0.00043 20.0 42.0 0.00043 20.0 29.1 3.1 2 1 0 3 3 3 1 Protein of unknown function (DUF1777) ATP_bind_1 PF03029.12 EPS33601.1 - 4.7e-76 255.4 0.0 6e-76 255.1 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 EPS33601.1 - 2e-05 24.1 0.0 0.00091 18.7 0.0 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ArgK PF03308.11 EPS33601.1 - 3.7e-05 22.6 0.0 0.015 14.1 0.0 2.3 2 0 0 2 2 2 2 ArgK protein AAA_10 PF12846.2 EPS33601.1 - 0.00016 21.2 0.0 0.00025 20.6 0.0 1.4 1 1 0 1 1 1 1 AAA-like domain MMR_HSR1 PF01926.18 EPS33601.1 - 0.00037 20.4 0.0 0.0014 18.6 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EPS33601.1 - 0.00081 19.5 0.0 0.0024 18.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain PRK PF00485.13 EPS33601.1 - 0.0027 17.3 0.1 0.036 13.6 0.0 2.2 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family Miro PF08477.8 EPS33601.1 - 0.0035 17.8 0.0 4.4 7.8 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein FeoB_N PF02421.13 EPS33601.1 - 0.0035 16.6 0.0 0.089 12.0 0.0 2.5 3 0 0 3 3 3 1 Ferrous iron transport protein B NACHT PF05729.7 EPS33601.1 - 0.0049 16.5 0.0 0.014 15.0 0.0 1.7 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.1 EPS33601.1 - 0.0067 16.3 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EPS33601.1 - 0.0067 16.0 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 EPS33601.1 - 0.0087 15.5 0.0 0.061 12.7 0.0 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_17 PF13207.1 EPS33601.1 - 0.014 16.2 0.9 0.032 15.0 0.0 2.0 2 1 0 2 2 1 0 AAA domain MobB PF03205.9 EPS33601.1 - 0.016 14.9 0.0 0.039 13.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Arf PF00025.16 EPS33601.1 - 0.017 14.4 0.0 4.2 6.5 0.0 3.1 3 0 0 3 3 3 0 ADP-ribosylation factor family NB-ARC PF00931.17 EPS33601.1 - 0.024 13.5 0.0 0.044 12.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Methyltransf_32 PF13679.1 EPS33601.1 - 0.049 13.3 0.0 0.34 10.5 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain cobW PF02492.14 EPS33601.1 - 0.052 12.9 0.0 1.5 8.2 0.0 2.3 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.15 EPS33601.1 - 0.068 11.8 2.0 1.6 7.3 0.0 2.8 3 0 0 3 3 3 0 G-protein alpha subunit PduV-EutP PF10662.4 EPS33601.1 - 0.14 11.6 0.2 1.3 8.5 0.0 2.6 3 1 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 EPS33601.1 - 0.17 11.8 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain GST_N_3 PF13417.1 EPS33603.1 - 4.8e-25 87.5 0.1 9.7e-25 86.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EPS33603.1 - 6.6e-15 54.8 0.0 1.4e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EPS33603.1 - 1.2e-07 31.4 0.6 3e-07 30.2 0.4 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EPS33603.1 - 0.0025 17.7 0.0 0.0048 16.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 EPS33603.1 - 0.0038 17.1 0.0 0.0088 16.0 0.0 1.7 1 0 0 1 1 1 1 Glutaredoxin GST_C_3 PF14497.1 EPS33603.1 - 0.067 13.6 0.0 0.12 12.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain SUZ PF12752.2 EPS33604.1 - 0.00018 21.9 20.0 0.0047 17.4 0.4 4.1 4 0 0 4 4 4 2 SUZ domain SUZ-C PF12901.2 EPS33604.1 - 0.0025 17.4 0.9 0.0025 17.4 0.6 2.4 2 0 0 2 2 2 1 SUZ-C motif CRF PF00473.12 EPS33604.1 - 0.18 11.9 1.2 0.54 10.3 0.8 1.8 1 0 0 1 1 1 0 Corticotropin-releasing factor family Fungal_trans PF04082.13 EPS33606.1 - 5.2e-22 77.9 0.0 8.5e-22 77.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS33606.1 - 7.3e-05 22.6 4.9 7.3e-05 22.6 3.4 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 EPS33607.1 - 1.4e-24 86.9 0.3 1.8e-24 86.5 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPS33607.1 - 1.2e-18 67.7 0.0 1.3e-18 67.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPS33607.1 - 8.4e-12 45.1 0.2 1.2e-11 44.6 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPS33607.1 - 0.0071 15.8 0.4 0.12 11.7 0.3 2.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pantoate_transf PF02548.10 EPS33607.1 - 0.016 14.3 0.1 0.024 13.7 0.1 1.2 1 0 0 1 1 1 0 Ketopantoate hydroxymethyltransferase Aldo_ket_red PF00248.16 EPS33610.1 - 2.1e-59 200.6 0.0 2.4e-59 200.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Hydrolase_6 PF13344.1 EPS33611.1 - 4.8e-23 80.9 0.0 8.2e-23 80.2 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EPS33611.1 - 6.8e-19 67.3 0.0 1.7e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 EPS33611.1 - 0.00065 19.9 0.0 0.08 13.1 0.0 2.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPS33611.1 - 0.0019 18.6 0.0 0.013 15.9 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 EPS33611.1 - 0.1 11.9 0.1 0.25 10.6 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Apt1 PF10351.4 EPS33611.1 - 0.23 10.2 0.0 0.39 9.5 0.0 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain LRR_4 PF12799.2 EPS33614.1 - 3.4e-07 29.7 10.1 0.00085 18.8 0.2 4.9 3 2 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EPS33614.1 - 0.00047 19.9 5.0 1.1 9.4 0.0 5.6 6 0 0 6 6 6 2 Leucine Rich repeat F-box-like PF12937.2 EPS33614.1 - 0.0079 15.9 0.1 0.027 14.1 0.1 2.0 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EPS33614.1 - 0.0085 15.8 11.6 0.19 11.5 0.5 5.0 3 3 2 5 5 5 2 Leucine rich repeat LRR_7 PF13504.1 EPS33614.1 - 0.032 14.3 8.2 38 5.1 0.0 6.8 7 0 0 7 7 7 0 Leucine rich repeat LRR_1 PF00560.28 EPS33614.1 - 0.038 13.9 9.3 25 5.4 0.0 6.7 6 1 0 6 6 6 0 Leucine Rich Repeat BSD PF03909.12 EPS33615.1 - 1e-28 98.7 9.3 3.8e-14 52.1 0.5 2.8 3 0 0 3 3 3 2 BSD domain TFIIH_BTF_p62_N PF08567.6 EPS33615.1 - 3.7e-22 77.7 0.0 8e-22 76.6 0.0 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain UPF0149 PF03695.8 EPS33615.1 - 0.13 12.1 4.8 0.048 13.5 0.4 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0149) Crystallin PF00525.13 EPS33615.1 - 0.14 12.3 0.4 0.68 10.1 0.3 2.1 1 1 0 1 1 1 0 Alpha crystallin A chain, N terminal DUF1751 PF08551.5 EPS33616.1 - 0.0084 16.4 0.1 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) ING PF12998.2 EPS33617.1 - 2.4e-11 43.8 0.0 6e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EPS33617.1 - 8.2e-10 38.2 8.9 1.3e-09 37.5 6.2 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EPS33617.1 - 0.0083 16.2 1.0 0.018 15.1 0.7 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain DUF4378 PF14309.1 EPS33617.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4378) Prp19 PF08606.6 EPS33617.1 - 0.51 10.1 4.6 0.72 9.6 1.1 2.3 2 0 0 2 2 2 0 Prp19/Pso4-like Transket_pyr PF02779.19 EPS33618.1 - 1.9e-64 216.4 0.0 3e-64 215.7 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EPS33618.1 - 6.3e-56 189.2 0.0 9.4e-56 188.7 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF4449 PF14613.1 EPS33620.1 - 8.4e-65 217.6 1.7 8.4e-65 217.6 1.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Rox3 PF08633.5 EPS33624.1 - 8.4e-50 169.7 0.1 2.4e-49 168.2 0.0 1.8 2 0 0 2 2 2 1 Rox3 mediator complex subunit PBP1_TM PF14812.1 EPS33624.1 - 2.6 8.4 4.6 9.9 6.5 3.0 2.1 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Fungal_trans PF04082.13 EPS33625.1 - 3.9e-18 65.2 0.2 6.3e-18 64.5 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS33625.1 - 1.8e-09 37.3 11.3 3e-09 36.6 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EPS33627.1 - 1.2e-29 102.9 0.4 1.7e-29 102.5 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS33627.1 - 1.7e-08 34.2 7.5 3.2e-08 33.3 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PXB PF12828.2 EPS33627.1 - 0.029 13.9 0.3 0.052 13.1 0.2 1.3 1 0 0 1 1 1 0 PX-associated DUF4202 PF13875.1 EPS33628.1 - 3.1e-74 248.6 0.0 3.4e-74 248.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) Glyco_transf_92 PF01697.22 EPS33628.1 - 0.003 16.9 0.0 0.0041 16.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 92 VIT1 PF01988.14 EPS33629.1 - 5.7e-61 205.7 4.5 6.5e-61 205.5 3.1 1.0 1 0 0 1 1 1 1 VIT family ATP_synth_reg PF14960.1 EPS33629.1 - 0.03 13.5 0.8 0.073 12.2 0.5 1.6 1 0 0 1 1 1 0 ATP synthase regulation GCFC PF07842.7 EPS33631.1 - 1.1e-83 280.8 2.8 1.6e-83 280.2 2.0 1.2 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 EPS33631.1 - 4.9e-18 64.6 2.5 9.6e-18 63.7 1.7 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EPS33631.1 - 6.4e-09 35.5 1.3 2e-08 33.9 0.9 1.8 1 0 0 1 1 1 1 DExH-box splicing factor binding site Sod_Fe_C PF02777.13 EPS33632.1 - 2.6e-40 136.5 0.4 2.6e-40 136.5 0.3 1.8 2 1 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EPS33632.1 - 1.3e-30 105.4 2.2 2.2e-30 104.7 1.5 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Imm15 PF15590.1 EPS33632.1 - 0.073 12.1 2.1 0.83 8.7 0.1 3.0 3 1 1 4 4 4 0 Immunity protein 15 F-box PF00646.28 EPS33633.1 - 0.003 17.1 1.0 0.0076 15.8 0.0 2.1 2 0 0 2 2 2 1 F-box domain Microtub_assoc PF07989.6 EPS33634.1 - 0.012 15.4 3.4 0.012 15.4 2.3 2.8 2 1 1 3 3 3 0 Microtubule associated DUF4375 PF14300.1 EPS33634.1 - 0.13 12.2 0.7 0.27 11.2 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4375) APG6 PF04111.7 EPS33634.1 - 0.6 9.0 9.0 0.96 8.4 6.2 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Sld5 PF05916.6 EPS33635.1 - 1.3e-15 57.6 0.0 1.6e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein Metallophos PF00149.23 EPS33636.1 - 3.4e-12 46.1 0.1 6.3e-12 45.3 0.1 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EPS33636.1 - 1.2e-06 28.4 0.0 5.6e-06 26.2 0.0 2.0 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain His_Phos_2 PF00328.17 EPS33637.1 - 1.3e-14 54.3 0.0 3.1e-13 49.7 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) NOA36 PF06524.7 EPS33638.1 - 0.19 10.9 1.0 0.35 10.0 0.7 1.3 1 0 0 1 1 1 0 NOA36 protein DUF1241 PF06840.6 EPS33639.1 - 0.16 11.2 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) AIRC PF00731.15 EPS33640.1 - 8.1e-58 193.9 4.0 1.7e-57 192.9 2.8 1.5 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 EPS33640.1 - 7.9e-53 178.3 0.0 1.5e-52 177.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EPS33640.1 - 1.7e-12 47.4 0.3 9.4e-12 45.0 0.0 2.3 2 1 0 2 2 2 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EPS33640.1 - 1.6e-06 27.5 0.1 4.3e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.8 EPS33640.1 - 2e-05 24.0 0.1 0.00034 20.0 0.0 2.7 2 1 0 2 2 2 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 EPS33640.1 - 0.00086 18.1 0.0 0.23 10.1 0.0 2.8 3 0 0 3 3 3 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 EPS33640.1 - 0.01 15.7 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain PrpR_N PF06506.6 EPS33640.1 - 0.018 14.4 1.6 0.024 14.0 0.1 1.9 2 0 0 2 2 2 0 Propionate catabolism activator CoA_binding_2 PF13380.1 EPS33640.1 - 0.04 14.0 1.2 15 5.7 0.1 3.4 2 1 1 3 3 3 0 CoA binding domain 2-Hacid_dh_C PF02826.14 EPS33640.1 - 0.077 12.1 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PPP4R2 PF09184.6 EPS33641.1 - 1.9e-10 40.8 3.0 1.4e-09 37.9 0.0 2.3 2 1 0 2 2 2 1 PPP4R2 Abhydrolase_1 PF00561.15 EPS33643.1 - 2e-22 79.9 0.0 7.6e-22 77.9 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EPS33643.1 - 1.6e-21 77.2 0.4 2.2e-21 76.7 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPS33643.1 - 4.6e-08 32.9 0.0 2.6e-07 30.5 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EPS33643.1 - 0.00061 19.5 0.0 0.0014 18.4 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_4 PF08386.5 EPS33643.1 - 0.016 15.1 0.1 0.038 13.8 0.0 1.6 2 0 0 2 2 2 0 TAP-like protein Peptidase_S28 PF05577.7 EPS33643.1 - 0.073 11.6 0.0 0.11 11.0 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 E1-E2_ATPase PF00122.15 EPS33644.1 - 1.3e-51 174.8 0.2 2.6e-51 173.8 0.1 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HMA PF00403.21 EPS33644.1 - 5.8e-44 148.0 0.3 6.6e-11 42.1 0.0 4.4 4 0 0 4 4 4 4 Heavy-metal-associated domain Hydrolase PF00702.21 EPS33644.1 - 3.4e-43 148.5 0.2 7.7e-43 147.3 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EPS33644.1 - 2.1e-13 50.8 0.1 7.3e-13 49.1 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EPS33644.1 - 2e-06 27.6 0.3 9.3e-05 22.1 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase GFA PF04828.9 EPS33644.1 - 0.036 14.0 0.1 6 6.8 0.0 3.0 3 0 0 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme PCI PF01399.22 EPS33645.1 - 1.8e-05 24.9 0.0 3.6e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 PCI domain RGS PF00615.14 EPS33646.1 - 9e-12 45.1 0.0 2.5e-08 34.0 0.0 2.4 2 0 0 2 2 2 2 Regulator of G protein signaling domain Bromodomain PF00439.20 EPS33647.1 - 1.9e-26 91.7 0.9 3.6e-26 90.8 0.7 1.4 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 EPS33647.1 - 9.2e-10 38.5 0.1 2.3e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPS33647.1 - 3.6e-09 36.5 0.1 8.7e-09 35.3 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Rad1 PF02144.11 EPS33648.1 - 4e-94 314.4 0.0 4.9e-94 314.1 0.0 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 AAA_23 PF13476.1 EPS33649.1 - 7.6e-28 98.2 1.5 7.6e-28 98.2 1.0 7.4 3 2 2 5 5 5 1 AAA domain SMC_N PF02463.14 EPS33649.1 - 5.1e-15 55.2 5.5 6.6e-10 38.5 1.8 3.8 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 EPS33649.1 - 1.4e-11 44.1 0.0 4.2e-11 42.6 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 EPS33649.1 - 2e-06 28.0 10.3 0.0018 18.2 0.4 3.8 3 2 0 3 3 3 2 AAA domain AAA_13 PF13166.1 EPS33649.1 - 0.00038 19.0 0.1 0.00038 19.0 0.0 7.3 2 1 3 7 7 7 2 AAA domain AAA_29 PF13555.1 EPS33649.1 - 0.00079 18.9 0.0 0.0018 17.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain KNOX2 PF03791.8 EPS33649.1 - 0.0048 16.1 0.0 0.26 10.6 0.1 3.3 2 0 0 2 2 2 1 KNOX2 domain AAA_15 PF13175.1 EPS33649.1 - 0.035 13.1 0.0 0.035 13.1 0.0 5.0 3 2 0 4 4 4 0 AAA ATPase domain MobB PF03205.9 EPS33649.1 - 0.069 12.8 4.2 0.068 12.8 0.4 2.9 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 EPS33649.1 - 0.09 13.0 0.0 0.09 13.0 0.0 7.2 3 2 0 3 3 3 0 ABC transporter GATA PF00320.22 EPS33650.1 - 1.2e-15 56.5 5.4 2.2e-15 55.6 3.7 1.5 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.19 EPS33650.1 - 4.4e-09 36.1 0.1 2.4e-08 33.7 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 EPS33650.1 - 2.6e-08 34.1 0.0 5.9e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.5 EPS33650.1 - 5.4e-07 29.6 0.0 1.1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_3 PF08447.6 EPS33650.1 - 7.2e-07 29.2 0.0 1.3e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 PAS fold NAD_binding_6 PF08030.7 EPS33652.1 - 1.1e-06 28.6 0.0 3.6e-05 23.7 0.0 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 EPS33652.1 - 1.5e-06 28.7 0.0 0.014 15.9 0.0 2.7 3 0 0 3 3 3 2 Oxidoreductase NAD-binding domain Metallophos PF00149.23 EPS33653.1 - 1.7e-09 37.3 0.6 5.7e-09 35.6 0.4 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EPS33653.1 - 3.3e-05 23.7 0.2 7.1e-05 22.6 0.2 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain HAD PF12710.2 EPS33654.1 - 1.9e-11 44.4 0.0 2.5e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EPS33654.1 - 0.0023 18.2 0.0 0.0062 16.7 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 EPS33654.1 - 0.021 14.1 0.1 0.066 12.5 0.0 1.8 1 1 1 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) GCD14 PF08704.5 EPS33655.1 - 2.4e-07 30.4 0.0 0.00071 19.1 0.0 2.3 2 0 0 2 2 2 2 tRNA methyltransferase complex GCD14 subunit Methyltransf_18 PF12847.2 EPS33655.1 - 0.003 18.1 0.0 2.9 8.5 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_26 PF13659.1 EPS33655.1 - 0.0035 17.3 0.0 0.0097 15.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Abhydrolase_6 PF12697.2 EPS33656.1 - 1.5e-21 77.3 0.2 1.9e-21 77.0 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EPS33656.1 - 2.9e-18 65.4 0.0 5e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 EPS33656.1 - 1e-13 51.2 0.0 1.5e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPS33656.1 - 0.00019 21.0 0.0 0.003 17.1 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EPS33656.1 - 0.02 14.3 0.0 0.25 10.7 0.0 2.4 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase DUF1749 PF08538.5 EPS33656.1 - 0.055 12.3 0.0 0.096 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Chlorophyllase2 PF12740.2 EPS33656.1 - 0.085 11.7 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Peptidase_S10 PF00450.17 EPS33656.1 - 0.13 11.3 0.0 7.4 5.6 0.0 2.1 2 0 0 2 2 2 0 Serine carboxypeptidase LRR_8 PF13855.1 EPS33657.1 - 1.3e-20 72.8 17.9 2.2e-10 40.1 2.5 2.2 1 1 2 3 3 3 3 Leucine rich repeat Exo_endo_phos PF03372.18 EPS33657.1 - 2.2e-19 70.3 0.1 4e-19 69.5 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 EPS33657.1 - 6.6e-19 67.1 5.2 1.7e-10 40.2 0.9 2.4 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EPS33657.1 - 5.7e-10 37.8 4.0 0.0075 16.1 0.0 4.9 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 EPS33657.1 - 3.8e-07 29.2 9.2 0.23 11.8 0.1 4.9 4 0 0 4 4 4 3 Leucine rich repeat LRR_6 PF13516.1 EPS33657.1 - 0.02 14.9 10.9 1 9.6 0.0 5.2 5 1 0 5 5 5 0 Leucine Rich repeat Methyltransf_11 PF08241.7 EPS33658.1 - 6.3e-09 36.2 0.0 1.1e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPS33658.1 - 1.1e-08 35.3 0.0 1.8e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS33658.1 - 8.1e-05 23.1 0.0 0.00023 21.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPS33658.1 - 9.8e-05 21.5 0.0 0.00015 20.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EPS33658.1 - 9.8e-05 21.9 0.0 0.00015 21.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPS33658.1 - 0.0001 22.1 0.0 0.00022 20.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPS33658.1 - 0.0041 17.1 0.0 0.012 15.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPS33658.1 - 0.0089 16.4 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Complex1_LYR_2 PF13233.1 EPS33659.1 - 2e-10 41.0 1.9 2.5e-10 40.7 1.3 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EPS33659.1 - 1.7e-06 27.6 0.6 2.7e-06 27.0 0.3 1.4 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EPS33659.1 - 3.6e-06 27.0 0.4 4.9e-06 26.6 0.3 1.3 1 1 0 1 1 1 1 Complex1_LYR-like Ribosomal_L29 PF00831.18 EPS33659.1 - 0.074 12.7 0.1 0.37 10.4 0.0 1.9 2 0 0 2 2 2 0 Ribosomal L29 protein 4HBT_2 PF13279.1 EPS33660.1 - 2.2e-27 95.8 0.1 3.6e-27 95.2 0.1 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 EPS33660.1 - 1.2e-05 25.3 0.0 2.1e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-ACP_TE PF01643.12 EPS33660.1 - 0.02 13.8 0.5 0.038 12.9 0.0 1.7 2 0 0 2 2 2 0 Acyl-ACP thioesterase MmgE_PrpD PF03972.9 EPS33661.1 - 2.3e-99 332.6 0.2 2.6e-99 332.4 0.1 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Serglycin PF04360.7 EPS33662.1 - 0.018 14.7 4.0 0.056 13.1 2.8 1.8 1 0 0 1 1 1 0 Serglycin Flavin_Reduct PF01613.13 EPS33663.1 - 2.4e-29 102.1 0.2 3.9e-29 101.4 0.1 1.4 1 0 0 1 1 1 1 Flavin reductase like domain DUF4505 PF14956.1 EPS33663.1 - 0.021 14.4 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4505) DUF1556 PF07590.6 EPS33663.1 - 1.4 9.1 5.6 0.83 9.9 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1556) Vps5 PF09325.5 EPS33665.1 - 8.6e-89 296.8 3.9 1.4e-88 296.1 2.7 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EPS33665.1 - 1.5e-23 82.7 0.0 3.4e-23 81.5 0.0 1.6 1 0 0 1 1 1 1 PX domain Aldolase_II PF00596.16 EPS33666.1 - 2.6e-40 138.0 0.0 3e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Calreticulin PF00262.13 EPS33667.1 - 1.2e-166 553.9 15.7 1.5e-166 553.6 10.9 1.1 1 0 0 1 1 1 1 Calreticulin family Aldedh PF00171.17 EPS33668.1 - 1.4e-135 452.2 0.4 1.7e-135 451.9 0.3 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Dynamitin PF04912.9 EPS33670.1 - 1.1e-27 96.8 3.1 1.1e-15 57.3 0.0 2.9 2 1 0 2 2 2 2 Dynamitin CCDC32 PF14989.1 EPS33670.1 - 0.01 15.6 0.7 0.026 14.3 0.5 1.7 1 0 0 1 1 1 0 Coiled-coil domain containing 32 Jnk-SapK_ap_N PF09744.4 EPS33670.1 - 0.022 14.7 3.0 0.48 10.4 0.0 2.3 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Prefoldin_2 PF01920.15 EPS33670.1 - 0.072 12.8 3.1 1.3 8.8 0.4 3.0 4 0 0 4 4 4 0 Prefoldin subunit DivIC PF04977.10 EPS33670.1 - 0.13 11.7 0.2 0.13 11.7 0.1 3.7 3 1 1 4 4 4 0 Septum formation initiator FlxA PF14282.1 EPS33670.1 - 0.29 11.0 2.5 2.6 8.0 0.1 3.1 3 0 0 3 3 3 0 FlxA-like protein Spc24 PF08286.6 EPS33670.1 - 0.33 10.6 1.9 18 5.0 0.1 2.8 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 Laminin_II PF06009.7 EPS33670.1 - 0.37 10.5 3.9 1.3 8.7 0.0 3.1 3 0 0 3 3 3 0 Laminin Domain II Viral_P18 PF04521.8 EPS33670.1 - 0.67 9.4 3.7 21 4.5 0.2 3.2 3 0 0 3 3 3 0 ssRNA positive strand viral 18kD cysteine rich protein MbeD_MobD PF04899.7 EPS33670.1 - 1.2 9.1 4.8 7.6 6.5 0.4 3.5 4 0 0 4 4 4 0 MbeD/MobD like Pkinase PF00069.20 EPS33672.1 - 3.3e-71 239.4 0.0 4.6e-71 239.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS33672.1 - 5.4e-35 120.7 0.1 9.5e-35 119.9 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EPS33672.1 - 5.4e-05 22.2 0.0 7.8e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EPS33672.1 - 0.0011 18.3 0.0 0.0031 16.8 0.0 1.7 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kdo PF06293.9 EPS33672.1 - 0.0086 15.1 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EPS33672.1 - 0.11 12.2 0.1 0.26 10.9 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.20 EPS33674.1 - 6.1e-57 192.7 0.0 8.3e-57 192.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS33674.1 - 1.1e-41 142.6 0.0 1.5e-41 142.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPS33674.1 - 6.1e-06 25.4 0.0 9.8e-06 24.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EPS33674.1 - 0.0017 18.1 0.0 0.013 15.2 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EPS33674.1 - 0.015 14.3 0.0 0.036 13.1 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EPS33674.1 - 0.097 12.0 0.1 0.37 10.1 0.1 1.9 1 1 0 1 1 1 0 RIO1 family Aminotran_1_2 PF00155.16 EPS33676.1 - 2.7e-18 66.0 0.0 3.5e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EPS33676.1 - 0.0003 19.9 0.0 0.0019 17.3 0.0 2.0 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_MocR PF12897.2 EPS33676.1 - 0.0021 16.6 0.0 0.006 15.1 0.0 1.6 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Dscam_C PF12355.3 EPS33676.1 - 0.079 13.2 0.1 0.25 11.6 0.1 1.8 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal NOSIC PF08060.8 EPS33676.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 NOSIC (NUC001) domain TPP_enzyme_N PF02776.13 EPS33677.1 - 3.7e-42 143.7 0.1 1.1e-41 142.1 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EPS33677.1 - 2.8e-22 78.9 0.0 2.4e-21 75.9 0.0 2.5 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EPS33677.1 - 6.9e-21 74.4 0.0 1.2e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain BCDHK_Adom3 PF10436.4 EPS33678.1 - 2.7e-42 144.0 0.0 3.9e-42 143.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EPS33678.1 - 5.8e-17 61.4 0.0 2.1e-16 59.6 0.0 1.8 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Inhibitor_I9 PF05922.11 EPS33679.1 - 1.5e-08 35.0 0.3 1.7e-08 34.9 0.2 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF1989 PF09347.5 EPS33680.1 - 2.1e-52 176.9 0.0 2.5e-51 173.4 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1989) DUF663 PF04950.7 EPS33681.1 - 9.4e-94 313.7 0.1 3e-93 312.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EPS33681.1 - 8e-25 86.1 0.0 1.8e-24 85.0 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 EPS33681.1 - 3.9e-07 29.6 0.0 5.5e-05 22.6 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 EPS33681.1 - 1.9e-05 24.7 0.0 5.1e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EPS33681.1 - 2.1e-05 24.6 0.0 5.4e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EPS33681.1 - 4.3e-05 23.8 1.5 9.6e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 ABC transporter MobB PF03205.9 EPS33681.1 - 0.00011 21.9 0.1 0.00026 20.7 0.1 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EPS33681.1 - 0.00049 19.3 0.0 0.00092 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 NACHT PF05729.7 EPS33681.1 - 0.00051 19.7 0.1 0.0012 18.4 0.1 1.7 1 1 0 1 1 1 1 NACHT domain PduV-EutP PF10662.4 EPS33681.1 - 0.00052 19.5 0.1 0.0037 16.7 0.1 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 EPS33681.1 - 0.00075 20.3 0.0 0.00075 20.3 0.0 4.6 3 1 0 3 3 1 1 AAA domain AAA_33 PF13671.1 EPS33681.1 - 0.00091 19.1 0.0 0.0031 17.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 EPS33681.1 - 0.0015 18.9 0.0 0.0047 17.4 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EPS33681.1 - 0.002 18.0 0.0 0.0052 16.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.1 EPS33681.1 - 0.0042 16.9 0.0 0.01 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EPS33681.1 - 0.0048 16.6 0.8 0.012 15.2 0.0 2.0 2 0 0 2 2 1 1 Archaeal ATPase AAA PF00004.24 EPS33681.1 - 0.0068 16.6 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EPS33681.1 - 0.0092 15.3 0.0 0.028 13.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EPS33681.1 - 0.015 14.1 0.7 0.024 13.4 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain RNA_helicase PF00910.17 EPS33681.1 - 0.017 15.2 0.0 0.046 13.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase SRP54 PF00448.17 EPS33681.1 - 0.035 13.5 0.1 0.072 12.5 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain SRPRB PF09439.5 EPS33681.1 - 0.039 13.1 0.0 0.08 12.1 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_18 PF13238.1 EPS33681.1 - 0.041 14.1 0.0 0.041 14.1 0.0 4.0 2 1 2 5 5 3 0 AAA domain KAP_NTPase PF07693.9 EPS33681.1 - 0.052 12.5 0.0 0.12 11.3 0.0 1.5 1 0 0 1 1 1 0 KAP family P-loop domain NTPase_1 PF03266.10 EPS33681.1 - 0.058 13.1 0.4 0.13 11.9 0.3 1.6 1 0 0 1 1 1 0 NTPase cobW PF02492.14 EPS33681.1 - 0.069 12.5 0.2 0.13 11.6 0.2 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EPS33681.1 - 0.074 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.1 EPS33681.1 - 0.093 12.4 0.1 0.23 11.2 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain Pox_A32 PF04665.7 EPS33681.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_21 PF13304.1 EPS33681.1 - 0.12 12.3 0.0 0.12 12.3 0.0 2.9 2 1 0 2 2 1 0 AAA domain UPF0079 PF02367.12 EPS33681.1 - 0.12 11.9 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 MFS_1 PF07690.11 EPS33683.1 - 2.2e-40 138.4 33.1 2.2e-40 138.4 22.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EPS33683.1 - 5.4e-10 38.0 2.6 1e-09 37.2 1.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EPS33683.1 - 1.6e-05 23.7 30.9 3.6e-05 22.5 21.4 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter Fungal_trans PF04082.13 EPS33684.1 - 4.7e-17 61.7 0.5 7e-17 61.1 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 EPS33684.1 - 1.7e-07 31.2 11.7 5.3e-07 29.6 2.0 2.7 3 0 0 3 3 3 2 Zinc-finger double domain DUF3499 PF12005.3 EPS33684.1 - 0.0091 16.1 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3499) zf-C2H2_4 PF13894.1 EPS33684.1 - 0.13 12.6 16.1 0.039 14.2 3.4 3.1 2 1 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EPS33684.1 - 0.53 10.7 18.5 0.067 13.5 2.4 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type Glyoxalase_2 PF12681.2 EPS33685.1 - 6.5e-15 55.6 0.1 2e-14 54.1 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EPS33685.1 - 3.5e-13 49.6 0.0 1.8e-12 47.3 0.0 2.1 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EPS33685.1 - 2.2e-06 27.6 0.0 4.7e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily PaaX PF07848.7 EPS33685.1 - 0.021 14.8 0.0 0.063 13.2 0.0 1.7 2 0 0 2 2 2 0 PaaX-like protein RRM_6 PF14259.1 EPS33686.1 - 2.8e-11 43.2 0.2 3.5e-09 36.4 0.0 2.9 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 EPS33686.1 - 2.3e-09 37.2 0.4 6.4e-09 35.7 0.2 1.8 2 0 0 2 2 2 1 PWI domain RRM_5 PF13893.1 EPS33686.1 - 2.4e-08 33.6 0.2 6.7e-08 32.2 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPS33686.1 - 2.6e-08 33.3 1.6 3.2e-06 26.6 0.0 3.4 4 0 0 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPS33686.1 - 1.4e-06 27.9 0.0 4.7e-05 23.0 0.0 2.5 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 EPS33686.1 - 0.012 15.2 1.9 0.023 14.3 1.3 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_3 PF08777.6 EPS33686.1 - 0.028 14.2 3.1 0.095 12.5 0.0 2.6 3 0 0 3 3 3 0 RNA binding motif BTV_NS2 PF04514.7 EPS33686.1 - 4.1 6.1 7.5 6.5 5.5 5.2 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 GTP_EFTU PF00009.22 EPS33687.1 - 6.7e-60 201.7 0.1 9.2e-60 201.2 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EPS33687.1 - 1.7e-37 127.6 0.0 4.2e-37 126.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EPS33687.1 - 2.1e-22 78.7 0.0 6.8e-22 77.1 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EPS33687.1 - 5.3e-13 48.8 0.1 3.9e-12 46.1 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EPS33687.1 - 1.2e-11 44.3 0.0 4e-11 42.6 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EPS33687.1 - 0.00019 21.3 0.0 0.00038 20.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Frigida PF07899.6 EPS33687.1 - 0.033 12.9 0.0 0.062 12.0 0.0 1.3 1 0 0 1 1 1 0 Frigida-like protein CTV_P23 PF04808.7 EPS33688.1 - 0.066 12.5 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Citrus tristeza virus (CTV) P23 protein Solute_trans_a PF03619.11 EPS33689.1 - 4.4e-102 341.0 5.3 5.6e-102 340.7 3.7 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Dynactin PF12455.3 EPS33691.1 - 2.6e-89 298.7 10.7 2.6e-89 298.7 7.4 4.1 3 1 1 4 4 4 1 Dynein associated protein CAP_GLY PF01302.20 EPS33691.1 - 5.2e-22 77.3 0.2 9.2e-22 76.5 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain IncA PF04156.9 EPS33691.1 - 0.0007 19.2 11.7 0.0007 19.2 8.1 7.4 4 2 2 6 6 6 1 IncA protein HAD_2 PF13419.1 EPS33692.1 - 1.1e-29 103.8 0.0 1.8e-29 103.1 0.0 1.3 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EPS33692.1 - 1.8e-05 25.2 0.0 2.8e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EPS33692.1 - 2.8e-05 23.7 0.0 5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like KH_1 PF00013.24 EPS33695.1 - 1.3e-28 98.4 4.2 1e-07 31.4 0.2 7.5 8 0 0 8 8 8 5 KH domain KH_3 PF13014.1 EPS33695.1 - 3.5e-23 80.7 2.5 0.00028 20.4 0.0 6.3 5 0 0 5 5 5 4 KH domain HATPase_c_5 PF14501.1 EPS33695.1 - 0.073 12.7 0.9 0.17 11.5 0.2 1.9 1 1 1 2 2 2 0 GHKL domain Glyco_hydro_2_N PF02837.13 EPS33697.1 - 9.6e-28 96.8 0.0 2.2e-27 95.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EPS33697.1 - 2.3e-15 56.2 0.0 4.2e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 EPS33697.1 - 6.5e-07 29.7 0.0 3e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 EPS33697.1 - 0.009 16.2 0.0 0.028 14.6 0.0 1.8 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain p450 PF00067.17 EPS33698.1 - 9.3e-77 258.4 0.0 1.1e-76 258.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Chitin_synth_2 PF03142.10 EPS33699.1 - 4.3e-230 764.6 0.0 6.6e-230 763.9 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EPS33699.1 - 1.6e-72 244.6 0.0 3.7e-72 243.4 0.0 1.4 1 1 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 EPS33699.1 - 2.1e-20 72.2 0.0 6e-10 38.7 0.0 2.6 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 EPS33699.1 - 1.7e-17 63.7 1.8 1.7e-17 63.7 1.2 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 DEK_C PF08766.6 EPS33699.1 - 7.5e-16 57.6 1.0 2.2e-15 56.1 0.5 2.0 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.1 EPS33699.1 - 1.6e-14 54.2 0.0 4e-12 46.4 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EPS33699.1 - 9e-07 28.3 0.0 5.9e-05 22.4 0.0 2.7 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EPS33699.1 - 0.0035 17.0 0.0 0.098 12.3 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Jiv90 PF14901.1 EPS33699.1 - 0.091 12.7 0.9 8.6 6.4 0.0 2.4 2 0 0 2 2 2 0 Cleavage inducing molecular chaperone Chitin_synth_2 PF03142.10 EPS33700.1 - 2.2e-254 844.7 2.1 2.9e-254 844.3 1.5 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EPS33700.1 - 1.1e-181 605.4 0.0 1.4e-181 605.0 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 EPS33700.1 - 9.8e-21 73.3 0.0 6.8e-14 51.4 0.0 2.9 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 EPS33700.1 - 4.5e-19 67.9 0.1 2.5e-17 62.3 0.1 2.7 2 0 0 2 2 2 1 DEK C terminal domain Glyco_trans_2_3 PF13632.1 EPS33700.1 - 4.1e-13 49.4 3.7 4.1e-13 49.4 2.5 2.3 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EPS33700.1 - 3.9e-12 46.4 0.0 2.6e-09 37.2 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EPS33700.1 - 0.001 18.8 0.0 0.033 13.8 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 AAA_16 PF13191.1 EPS33700.1 - 0.0081 16.1 0.1 0.022 14.7 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EPS33700.1 - 0.025 14.7 0.0 0.071 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Glyco_transf_21 PF13506.1 EPS33700.1 - 0.025 13.8 0.0 0.12 11.6 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 21 DUF258 PF03193.11 EPS33700.1 - 0.15 11.2 0.0 0.37 9.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 GCN5L1 PF06320.8 EPS33701.1 - 1.2e-13 50.9 0.6 1.8e-13 50.3 0.4 1.2 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) MutL_C PF08676.6 EPS33702.1 - 1.6e-24 86.1 0.0 3.4e-24 85.1 0.0 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 EPS33702.1 - 1.3e-18 66.6 0.0 2.4e-17 62.4 0.0 3.0 3 0 0 3 3 3 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EPS33702.1 - 1.8e-13 50.3 0.0 5.1e-13 48.8 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EPS33702.1 - 8.7e-12 44.7 0.0 2.4e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Daxx PF03344.10 EPS33702.1 - 0.94 7.8 40.0 0.0047 15.4 20.6 2.0 2 0 0 2 2 2 0 Daxx Family Serinc PF03348.10 EPS33703.1 - 8.6e-177 588.1 9.5 9.7e-177 587.9 6.6 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) PGA2 PF07543.7 EPS33703.1 - 0.38 10.5 3.2 7 6.4 0.4 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 Nodulin-like PF06813.8 EPS33704.1 - 2.5e-20 72.7 1.4 5.8e-20 71.5 0.9 1.6 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.11 EPS33704.1 - 6.9e-12 44.7 39.1 3.8e-11 42.2 23.2 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily GATA PF00320.22 EPS33705.1 - 3.8e-16 58.1 2.6 6.7e-16 57.3 1.8 1.4 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 EPS33705.1 - 0.012 14.9 0.4 0.022 14.0 0.3 1.4 1 0 0 1 1 1 0 TFIIB zinc-binding DZR PF12773.2 EPS33705.1 - 0.091 12.5 0.7 0.31 10.8 0.4 1.8 1 1 0 1 1 1 0 Double zinc ribbon DUF4618 PF15397.1 EPS33705.1 - 0.1 11.9 2.0 0.14 11.4 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) zf-ribbon_3 PF13248.1 EPS33705.1 - 0.33 10.2 1.9 0.78 9.0 1.3 1.6 1 1 0 1 1 1 0 zinc-ribbon domain DivIVA PF05103.8 EPS33705.1 - 0.62 10.1 5.4 1.6 8.8 3.8 1.6 1 1 0 1 1 1 0 DivIVA protein WD40_alt PF14077.1 EPS33705.1 - 7.3 6.3 7.9 43 3.8 0.0 3.2 2 1 1 3 3 3 0 Alternative WD40 repeat motif PI3_PI4_kinase PF00454.22 EPS33706.1 - 1.1e-38 133.0 0.0 1.5e-38 132.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase SNF2_N PF00176.18 EPS33707.1 - 2.4e-61 207.1 0.9 4.1e-61 206.3 0.6 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPS33707.1 - 1.4e-07 31.2 0.0 3.6e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HIRAN PF08797.6 EPS33707.1 - 0.015 15.2 0.0 0.086 12.7 0.0 2.3 3 0 0 3 3 3 0 HIRAN domain zf-RING_UBOX PF13445.1 EPS33707.1 - 0.039 13.6 2.0 0.089 12.5 1.4 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Ribosomal_S27e PF01667.12 EPS33707.1 - 0.26 10.8 5.2 0.66 9.5 3.6 1.6 1 0 0 1 1 1 0 Ribosomal protein S27 Med21 PF11221.3 EPS33709.1 - 4.6e-58 195.2 0.2 6.6e-58 194.7 0.1 1.2 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.8 EPS33709.1 - 0.0012 18.5 3.6 0.022 14.4 2.7 2.5 1 1 1 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 ATG16 PF08614.6 EPS33709.1 - 0.0016 18.3 0.2 0.0024 17.7 0.2 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) LMP PF04778.7 EPS33709.1 - 0.046 13.4 0.1 0.064 13.0 0.1 1.2 1 0 0 1 1 1 0 LMP repeated region Spore_III_AB PF09548.5 EPS33709.1 - 0.058 13.1 1.0 0.076 12.7 0.2 1.5 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DUF4407 PF14362.1 EPS33709.1 - 0.072 12.0 0.5 0.099 11.5 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) IncA PF04156.9 EPS33709.1 - 0.074 12.6 1.6 0.16 11.5 0.4 2.0 2 0 0 2 2 2 0 IncA protein AAA_13 PF13166.1 EPS33709.1 - 0.13 10.7 0.7 0.16 10.3 0.5 1.1 1 0 0 1 1 1 0 AAA domain SPX PF03105.14 EPS33709.1 - 0.13 11.9 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 SPX domain Cortex-I_coil PF09304.5 EPS33709.1 - 0.14 12.2 4.1 0.22 11.5 2.8 1.3 1 0 0 1 1 1 0 Cortexillin I, coiled coil DUF2721 PF11026.3 EPS33709.1 - 0.19 11.4 0.3 0.3 10.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) APG6 PF04111.7 EPS33709.1 - 0.19 10.7 2.2 0.26 10.2 1.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Pox_A_type_inc PF04508.7 EPS33709.1 - 0.36 10.7 5.4 3.8 7.5 0.8 3.1 2 1 0 2 2 2 0 Viral A-type inclusion protein repeat Dzip-like_N PF13815.1 EPS33709.1 - 0.59 9.9 5.0 0.16 11.7 1.4 1.5 2 0 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal DUF641 PF04859.7 EPS33709.1 - 0.6 9.8 4.2 0.74 9.5 2.2 1.5 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Med4 PF10018.4 EPS33709.1 - 1.4 8.2 6.1 0.32 10.3 0.8 2.1 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Metal_resist PF13801.1 EPS33709.1 - 3.5 7.6 8.1 3.6 7.5 0.2 2.4 2 0 0 2 2 2 0 Heavy-metal resistance Prefoldin_2 PF01920.15 EPS33709.1 - 7 6.4 10.4 1.2 8.9 4.4 1.7 2 1 0 2 2 1 0 Prefoldin subunit DUF2034 PF10356.4 EPS33710.1 - 3.2e-42 143.7 0.0 2.4e-25 88.7 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 EPS33710.1 - 2.2e-09 37.1 0.0 3.7e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease Spc24 PF08286.6 EPS33711.1 - 9.4e-40 134.9 1.8 1e-38 131.6 0.0 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 IL2 PF00715.12 EPS33711.1 - 0.019 14.7 0.5 0.035 13.8 0.3 1.6 1 1 0 1 1 1 0 Interleukin 2 DASH_Dad1 PF08649.5 EPS33711.1 - 0.032 13.9 0.0 0.061 13.0 0.0 1.4 1 0 0 1 1 1 0 DASH complex subunit Dad1 DUF3166 PF11365.3 EPS33711.1 - 0.043 14.2 1.7 0.043 14.2 1.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3166) Streptin-Immun PF11083.3 EPS33711.1 - 0.12 12.4 2.2 0.53 10.2 0.0 2.2 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein V_ATPase_I PF01496.14 EPS33711.1 - 0.13 10.0 1.8 0.15 9.9 1.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 EPS33711.1 - 0.2 10.6 7.2 0.26 10.2 5.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF4613 PF15390.1 EPS33711.1 - 0.32 9.1 2.8 0.4 8.8 2.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Viral_P18 PF04521.8 EPS33711.1 - 0.98 8.8 7.3 0.22 11.0 0.8 2.1 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein SlyX PF04102.7 EPS33711.1 - 1.8 9.0 5.0 4.7 7.6 0.2 2.4 2 1 0 2 2 2 0 SlyX TBPIP PF07106.8 EPS33711.1 - 2 7.9 5.3 2.7 7.4 1.6 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Prefoldin_2 PF01920.15 EPS33711.1 - 2.4 7.9 8.3 4 7.2 2.3 2.2 1 1 1 2 2 2 0 Prefoldin subunit DUF724 PF05266.9 EPS33711.1 - 4.7 6.7 8.0 6.8 6.2 4.9 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF972 PF06156.8 EPS33711.1 - 7.8 6.8 6.2 3.4 8.0 1.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Fis1_TPR_C PF14853.1 EPS33712.1 - 3.6e-25 87.6 1.4 5.4e-25 87.0 1.0 1.3 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 EPS33712.1 - 2.7e-16 58.5 0.0 4.3e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 EPS33712.1 - 0.0094 15.8 2.2 0.0094 15.8 1.5 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EPS33712.1 - 0.012 16.2 0.4 0.025 15.2 0.3 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF357 PF04010.8 EPS33712.1 - 0.094 12.4 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF357) zf-RING_2 PF13639.1 EPS33713.1 - 1.2e-14 53.8 16.0 1.6e-14 53.4 6.0 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EPS33713.1 - 1.6e-10 40.5 6.9 3e-09 36.3 2.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EPS33713.1 - 2.8e-08 33.7 5.7 7.1e-08 32.4 4.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EPS33713.1 - 8e-08 32.1 7.6 8e-08 32.1 5.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPS33713.1 - 5.1e-07 29.2 12.1 6.2e-07 28.9 5.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_3 PF14369.1 EPS33713.1 - 5.9e-06 26.1 5.5 6.7e-05 22.8 0.4 2.7 2 0 0 2 2 2 1 zinc-finger zf-RING_5 PF14634.1 EPS33713.1 - 1.7e-05 24.4 10.7 3.7e-05 23.3 3.9 2.3 2 0 0 2 2 2 1 zinc-RING finger domain DUF1631 PF07793.6 EPS33713.1 - 0.0011 17.2 0.1 0.0011 17.2 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1631) zf-Apc11 PF12861.2 EPS33713.1 - 0.0067 16.2 3.0 0.0067 16.2 2.1 1.8 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EPS33713.1 - 0.011 15.2 4.2 0.011 15.2 2.9 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain UPF0547 PF10571.4 EPS33713.1 - 0.11 12.2 2.3 10 5.9 0.2 2.7 2 1 0 2 2 2 0 Uncharacterised protein family UPF0547 Baculo_RING PF05883.6 EPS33713.1 - 0.35 10.7 1.5 0.64 9.8 1.1 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain PHD PF00628.24 EPS33713.1 - 0.36 10.5 14.1 0.065 12.9 5.1 2.4 2 0 0 2 2 2 0 PHD-finger HypA PF01155.14 EPS33713.1 - 0.67 9.6 3.7 3.5 7.3 0.0 2.2 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-TFIIB PF13453.1 EPS33713.1 - 0.78 8.9 8.5 0.26 10.5 0.7 3.1 3 0 0 3 3 3 0 Transcription factor zinc-finger zf-RING_UBOX PF13445.1 EPS33713.1 - 2.7 7.7 12.9 0.031 14.0 3.2 2.2 2 0 0 2 2 1 0 RING-type zinc-finger FANCL_C PF11793.3 EPS33713.1 - 6 6.9 10.8 3.5 7.6 4.8 2.6 3 1 0 3 3 2 0 FANCL C-terminal domain Aminotran_5 PF00266.14 EPS33714.1 - 5.7e-22 77.9 0.0 8.2e-22 77.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EPS33714.1 - 0.035 13.1 0.0 0.72 8.8 0.0 2.3 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family SLA_LP_auto_ag PF05889.8 EPS33714.1 - 0.098 11.1 0.0 0.13 10.6 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) DUF3320 PF11784.3 EPS33714.1 - 0.11 12.0 0.0 0.28 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3320) bZIP_1 PF00170.16 EPS33715.1 - 3.2e-05 23.7 2.3 8.7e-05 22.4 1.6 1.7 1 0 0 1 1 1 1 bZIP transcription factor Phosphoesterase PF04185.9 EPS33716.1 - 7.1e-26 91.2 7.2 7.7e-25 87.8 5.0 2.2 1 1 0 1 1 1 1 Phosphoesterase family Activator_LAG-3 PF11498.3 EPS33716.1 - 0.073 11.8 0.0 0.11 11.1 0.0 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 GYF PF02213.11 EPS33717.1 - 1.3e-17 63.0 0.1 2.8e-17 62.0 0.1 1.6 1 0 0 1 1 1 1 GYF domain ADH_zinc_N PF00107.21 EPS33719.1 - 3.8e-25 87.9 0.6 6.3e-25 87.2 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPS33719.1 - 2e-11 44.8 0.2 5e-11 43.6 0.1 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPS33719.1 - 3.4e-06 26.7 0.0 6.2e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_7 PF13241.1 EPS33719.1 - 0.0095 16.1 0.8 5.5 7.3 0.1 2.3 2 0 0 2 2 2 2 Putative NAD(P)-binding NAD_binding_10 PF13460.1 EPS33719.1 - 0.033 14.1 0.7 0.077 12.9 0.5 1.5 1 1 0 1 1 1 0 NADH(P)-binding ADIP PF11559.3 EPS33720.1 - 0.038 13.8 1.0 0.29 11.0 0.4 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF241 PF03087.9 EPS33720.1 - 0.09 12.2 0.4 0.18 11.2 0.2 1.5 1 1 1 2 2 2 0 Arabidopsis protein of unknown function Trp_syntA PF00290.15 EPS33723.1 - 2.6e-92 308.0 0.0 4.4e-92 307.2 0.0 1.3 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 EPS33723.1 - 1e-46 159.5 1.1 1.6e-46 158.9 0.8 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ATP-synt_ab PF00006.20 EPS33724.1 - 1.2e-62 211.2 0.0 1.6e-62 210.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EPS33724.1 - 8.1e-16 58.5 0.1 1.5e-15 57.6 0.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EPS33724.1 - 2.3e-11 43.7 0.2 4.9e-11 42.6 0.1 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EPS33724.1 - 0.00015 21.6 0.2 0.00031 20.5 0.1 1.5 1 0 0 1 1 1 1 HAS barrel domain 2-Hacid_dh_C PF02826.14 EPS33725.1 - 2.2e-45 153.9 0.0 3.9e-45 153.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 EPS33725.1 - 0.00013 21.8 0.0 0.00042 20.2 0.0 1.7 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh PF00389.25 EPS33725.1 - 0.0006 19.2 0.0 0.0019 17.6 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain XdhC_C PF13478.1 EPS33725.1 - 0.0028 17.9 0.0 0.026 14.8 0.0 2.1 2 0 0 2 2 2 1 XdhC Rossmann domain ELFV_dehydrog PF00208.16 EPS33725.1 - 0.027 14.0 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Oxidored_nitro PF00148.14 EPS33725.1 - 0.067 11.8 0.0 0.11 11.1 0.0 1.3 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Yae1_N PF09811.4 EPS33727.1 - 7.2e-05 22.2 14.8 0.00012 21.5 10.3 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal E_Pc_C PF06752.7 EPS33727.1 - 4.4 6.7 6.3 4.7 6.6 4.4 1.2 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus Usp PF00582.21 EPS33728.1 - 4.6e-16 59.2 9.1 1.2e-15 57.9 0.5 4.0 3 1 0 3 3 3 1 Universal stress protein family NOA36 PF06524.7 EPS33728.1 - 3 7.0 14.4 5.8 6.0 10.0 1.4 1 0 0 1 1 1 0 NOA36 protein DnaJ PF00226.26 EPS33730.1 - 6.2e-22 77.1 1.5 1.8e-21 75.6 1.1 1.9 1 0 0 1 1 1 1 DnaJ domain Cas_Csy4 PF09618.5 EPS33730.1 - 3.2 7.5 10.2 1.6 8.5 4.4 2.2 1 1 2 3 3 3 0 CRISPR-associated protein (Cas_Csy4) dCMP_cyt_deam_1 PF00383.17 EPS33731.1 - 1.7e-11 43.6 0.0 9.1e-11 41.3 0.0 2.1 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 EPS33731.1 - 0.0013 18.4 0.1 0.0022 17.6 0.0 1.4 1 1 0 1 1 1 1 APOBEC-like N-terminal domain Stn1 PF10451.4 EPS33732.1 - 3.9e-12 45.5 0.1 1.5e-07 30.5 0.0 2.2 2 0 0 2 2 2 2 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.20 EPS33732.1 - 0.0066 16.2 0.0 0.92 9.4 0.0 2.6 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain DUF2570 PF10828.3 EPS33732.1 - 0.049 13.2 0.1 0.085 12.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Cas_Csy4 PF09618.5 EPS33732.1 - 0.13 12.0 0.8 0.19 11.4 0.5 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csy4) Pkinase PF00069.20 EPS33736.1 - 5.3e-58 196.2 0.0 8.1e-58 195.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS33736.1 - 1.8e-31 109.1 0.0 1.3e-29 103.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EPS33736.1 - 0.072 11.8 0.0 0.1 11.3 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RNase_PH PF01138.16 EPS33737.1 - 4e-14 53.0 0.0 1.1e-13 51.6 0.0 1.8 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Cytochrom_C PF00034.16 EPS33739.1 - 5.9e-12 46.2 0.0 8.3e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 EPS33739.1 - 1.3e-08 34.8 3.0 1.1e-07 31.8 2.1 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 EPS33739.1 - 4.5e-05 22.9 0.3 0.00012 21.5 0.1 1.8 2 0 0 2 2 2 1 Cytochrome c-550 domain Cytochrome-c551 PF10643.4 EPS33739.1 - 0.12 11.7 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 Baculo_PEP_C PF04513.7 EPS33740.1 - 0.11 12.2 2.4 0.31 10.8 0.1 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATE_C PF04377.10 EPS33741.1 - 3e-45 153.4 2.0 6.7e-45 152.2 1.4 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 EPS33741.1 - 2.1e-19 69.1 5.9 6.4e-19 67.5 4.2 1.7 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.1 EPS33741.1 - 0.019 14.8 0.5 0.036 14.0 0.4 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain NUDIX PF00293.23 EPS33742.1 - 8.3e-18 64.3 0.1 9.5e-18 64.1 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain RNA_pol_A_bac PF01000.21 EPS33743.1 - 1.6e-30 105.5 0.0 2.7e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EPS33743.1 - 1e-11 43.7 0.0 1.3e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain CYSTM PF12734.2 EPS33744.1 - 6.6 6.8 23.8 11 6.1 16.5 1.5 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance Calcipressin PF04847.7 EPS33746.1 - 8.2e-34 116.7 3.0 1.2e-33 116.2 2.1 1.3 1 0 0 1 1 1 1 Calcipressin Lipase_3 PF01764.20 EPS33747.1 - 4e-36 123.7 0.1 7e-36 122.9 0.1 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 EPS33747.1 - 0.0034 16.7 1.4 0.018 14.4 0.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) Esterase PF00756.15 EPS33747.1 - 0.0061 16.0 0.0 0.0078 15.6 0.0 1.2 1 0 0 1 1 1 1 Putative esterase PE-PPE PF08237.6 EPS33747.1 - 0.014 14.8 1.5 0.018 14.4 0.6 1.5 1 1 0 1 1 1 0 PE-PPE domain Thioesterase PF00975.15 EPS33747.1 - 0.017 15.3 0.0 0.027 14.7 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain DUF2048 PF09752.4 EPS33747.1 - 0.056 12.3 0.0 0.099 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Abhydrolase_5 PF12695.2 EPS33747.1 - 0.097 12.4 1.2 0.23 11.2 0.8 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Metallopep PF12044.3 EPS33748.1 - 6.8e-124 413.5 0.0 8.3e-124 413.2 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_2 PF13574.1 EPS33748.1 - 0.0012 18.9 0.2 0.0027 17.8 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EPS33748.1 - 0.0015 19.0 0.4 0.0089 16.5 0.3 2.2 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EPS33748.1 - 0.0042 16.6 0.5 0.0093 15.5 0.2 1.6 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EPS33748.1 - 0.0049 16.8 0.4 0.01 15.7 0.2 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 GrpE PF01025.14 EPS33749.1 - 2.8e-46 157.0 6.4 4.2e-46 156.5 4.5 1.2 1 0 0 1 1 1 1 GrpE Herpes_glycop_H PF02489.11 EPS33749.1 - 0.017 13.1 0.4 0.025 12.6 0.2 1.3 1 1 0 1 1 1 0 Herpesvirus glycoprotein H Luteo_P1-P2 PF08467.5 EPS33749.1 - 0.049 12.4 0.8 0.072 11.8 0.5 1.2 1 0 0 1 1 1 0 Luteovirus RNA polymerase P1-P2/replicase PMC2NT PF08066.7 EPS33749.1 - 0.077 13.3 2.3 0.1 12.9 0.5 2.0 2 0 0 2 2 2 0 PMC2NT (NUC016) domain DUF1615 PF07759.7 EPS33749.1 - 0.081 11.6 0.9 0.13 11.0 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1615) Lge1 PF11488.3 EPS33749.1 - 0.19 11.9 2.2 2 8.6 0.7 2.3 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 DUF4446 PF14584.1 EPS33749.1 - 0.32 10.8 3.0 5.2 6.8 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) Bap31 PF05529.7 EPS33749.1 - 2 7.8 5.9 2 7.8 3.5 1.5 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF848 PF05852.6 EPS33749.1 - 2.4 7.9 8.3 0.97 9.2 3.5 1.8 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) tRNA-synt_2d PF01409.15 EPS33750.1 - 1.7e-46 158.4 0.1 3.4e-25 88.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 EPS33750.1 - 2.8e-26 91.4 0.0 7.5e-26 90.1 0.0 1.8 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Mito_carr PF00153.22 EPS33751.1 - 2.4e-61 203.4 0.3 4.9e-20 71.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein COX6B PF02297.12 EPS33752.1 - 5.5e-19 67.9 8.1 6.4e-19 67.7 5.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb UCR_hinge PF02320.11 EPS33752.1 - 0.012 15.5 0.1 0.023 14.6 0.1 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein APOBEC_C PF05240.9 EPS33752.1 - 0.014 14.8 2.2 0.027 13.8 1.5 1.6 1 1 0 1 1 1 0 APOBEC-like C-terminal domain CHCH PF06747.8 EPS33752.1 - 0.058 13.3 1.0 0.15 12.0 0.7 1.7 1 1 0 1 1 1 0 CHCH domain ketoacyl-synt PF00109.21 EPS33752.1 - 0.13 11.7 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain B12D PF06522.6 EPS33753.1 - 8.4e-07 28.5 0.0 1.5e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit RRM_1 PF00076.17 EPS33754.1 - 4.7e-18 64.5 0.0 8.6e-18 63.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS33754.1 - 1.3e-12 47.5 0.1 2.2e-12 46.7 0.0 1.4 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS33754.1 - 2.1e-10 40.2 0.0 1.3e-09 37.7 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ureidogly_hydro PF04115.7 EPS33754.1 - 0.029 13.7 0.0 0.13 11.6 0.0 1.8 1 1 1 2 2 2 0 Ureidoglycolate hydrolase Limkain-b1 PF11608.3 EPS33754.1 - 0.08 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Limkain b1 Perilipin PF03036.11 EPS33754.1 - 0.098 11.4 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Perilipin family WD40 PF00400.27 EPS33755.1 - 1.4e-16 59.6 11.0 0.00019 21.2 0.3 6.8 5 2 1 6 6 6 4 WD domain, G-beta repeat SRA1 PF07304.6 EPS33755.1 - 1.6e-12 47.4 0.0 1.6e-12 47.4 0.0 2.5 2 1 1 3 3 3 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.2 EPS33755.1 - 0.012 15.3 0.1 0.047 13.4 0.1 1.9 1 1 0 1 1 1 0 Sec23-binding domain of Sec16 Pex14_N PF04695.8 EPS33756.1 - 9.4e-32 109.9 0.1 9.4e-32 109.9 0.1 2.7 3 0 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region E2R135 PF11570.3 EPS33756.1 - 0.0044 17.1 0.1 0.01 15.9 0.1 1.7 1 0 0 1 1 1 1 Coiled-coil receptor-binding R-domain of colicin E2 PAPA-1 PF04795.7 EPS33757.1 - 2.7e-29 101.6 3.3 2.7e-29 101.6 2.3 2.4 3 0 0 3 3 3 1 PAPA-1-like conserved region Mus7 PF09462.5 EPS33758.1 - 3.9e-187 623.8 2.4 3.9e-187 623.8 1.7 1.6 2 0 0 2 2 2 1 Mus7/MMS22 family DUF4050 PF13259.1 EPS33759.1 - 3.8e-41 139.8 0.9 6e-41 139.1 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) AAA PF00004.24 EPS33760.1 - 2.6e-39 134.4 0.1 1.1e-37 129.1 0.0 2.8 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EPS33760.1 - 2.3e-05 24.4 2.4 0.0059 16.6 0.0 3.9 1 1 2 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EPS33760.1 - 6.3e-05 23.1 0.3 0.0031 17.6 0.1 3.4 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EPS33760.1 - 9.4e-05 21.5 0.0 0.00022 20.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EPS33760.1 - 0.00012 21.9 0.3 0.0034 17.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain TIP49 PF06068.8 EPS33760.1 - 0.00049 18.9 0.2 0.0017 17.1 0.0 1.9 2 0 0 2 2 2 1 TIP49 C-terminus AAA_17 PF13207.1 EPS33760.1 - 0.00092 20.0 0.1 0.003 18.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPS33760.1 - 0.0011 18.6 0.9 0.0036 17.0 0.2 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_5 PF07728.9 EPS33760.1 - 0.0014 18.3 0.0 0.0035 17.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EPS33760.1 - 0.0033 17.3 0.0 0.015 15.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EPS33760.1 - 0.0045 16.4 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.1 EPS33760.1 - 0.0083 16.0 0.0 0.022 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EPS33760.1 - 0.015 14.4 0.1 0.039 13.1 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EPS33760.1 - 0.033 14.3 0.0 0.083 13.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 EPS33760.1 - 0.043 14.1 0.1 0.15 12.4 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_24 PF13479.1 EPS33760.1 - 0.06 12.9 0.2 0.15 11.6 0.2 1.6 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 EPS33760.1 - 0.081 11.7 0.0 0.22 10.3 0.0 1.7 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 SHQ1 PF04925.10 EPS33760.1 - 0.14 11.5 0.0 0.3 10.4 0.0 1.5 1 0 0 1 1 1 0 SHQ1 protein Zot PF05707.7 EPS33760.1 - 0.15 11.5 0.6 5.3 6.4 0.1 2.9 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) LIM_bind PF01803.11 EPS33761.1 - 9.4e-79 263.9 1.0 9.4e-79 263.9 0.7 3.7 2 1 1 3 3 3 1 LIM-domain binding protein cobW PF02492.14 EPS33762.1 - 1e-34 119.5 0.0 1.3e-34 119.2 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 EPS33762.1 - 3.1e-06 26.1 0.1 0.0075 15.0 0.0 2.0 2 0 0 2 2 2 2 ArgK protein MMR_HSR1 PF01926.18 EPS33762.1 - 0.0031 17.4 0.0 0.0066 16.3 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_5 PF07728.9 EPS33762.1 - 0.018 14.7 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EPS33762.1 - 0.019 14.3 0.0 0.053 12.9 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein CbiA PF01656.18 EPS33762.1 - 0.024 14.0 0.1 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_23 PF13476.1 EPS33762.1 - 0.026 14.8 0.0 0.054 13.8 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EPS33762.1 - 0.028 15.2 0.0 0.056 14.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 EPS33762.1 - 0.056 13.0 0.0 0.089 12.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain MobB PF03205.9 EPS33762.1 - 0.071 12.8 0.0 0.2 11.3 0.0 1.8 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 EPS33762.1 - 0.13 12.5 0.0 0.17 12.1 0.0 1.2 1 0 0 1 1 1 0 ABC transporter BING4CT PF08149.6 EPS33763.1 - 2.9e-38 129.2 0.0 1.9e-36 123.3 0.0 2.6 2 0 0 2 2 2 1 BING4CT (NUC141) domain WD40 PF00400.27 EPS33763.1 - 5.9e-05 22.8 0.0 0.0084 15.9 0.0 3.2 3 0 0 3 3 3 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EPS33763.1 - 0.045 12.5 0.0 0.099 11.4 0.0 1.5 2 0 0 2 2 2 0 Coatomer WD associated region DUF663 PF04950.7 EPS33764.1 - 5.7e-98 327.5 0.1 1e-97 326.7 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EPS33764.1 - 7.1e-24 83.1 0.0 1.6e-23 81.9 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain SNAP PF14938.1 EPS33765.1 - 4e-115 383.8 16.1 4.5e-115 383.6 11.1 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 EPS33765.1 - 6.4e-06 26.0 16.9 0.02 14.7 4.9 4.2 1 1 4 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 EPS33765.1 - 0.0007 19.1 15.5 0.18 11.4 2.0 4.4 2 1 1 4 4 4 2 TPR repeat TPR_7 PF13176.1 EPS33765.1 - 0.00077 19.0 13.4 0.022 14.5 0.7 5.2 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EPS33765.1 - 0.0042 16.8 20.9 0.087 12.7 0.7 7.1 4 1 3 8 8 8 2 Tetratricopeptide repeat TPR_6 PF13174.1 EPS33765.1 - 0.0043 17.4 14.6 0.68 10.5 0.6 6.3 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 EPS33765.1 - 0.0077 16.7 15.5 0.08 13.6 1.6 5.1 2 1 3 5 5 4 1 Tetratricopeptide repeat DUF2811 PF10929.3 EPS33765.1 - 0.01 15.8 0.1 0.034 14.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2811) TPR_1 PF00515.23 EPS33765.1 - 0.035 13.7 20.0 0.38 10.4 0.8 6.4 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.1 EPS33765.1 - 0.038 13.7 1.2 0.038 13.7 0.9 5.7 4 2 3 7 7 7 0 Tetratricopeptide repeat DUF932 PF06067.6 EPS33765.1 - 0.21 10.8 5.2 0.17 11.1 2.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF932) NSF PF02071.15 EPS33765.1 - 1.2 10.0 18.9 4.2 8.3 0.2 6.7 7 0 0 7 7 5 0 Aromatic-di-Alanine (AdAR) repeat TPR_3 PF07720.7 EPS33765.1 - 1.3 8.8 5.6 18 5.2 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Glu-tRNAGln PF02686.10 EPS33766.1 - 1.7e-06 27.7 0.6 7.2e-06 25.7 0.4 2.0 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit Creb_binding PF09030.5 EPS33766.1 - 0.087 13.0 3.1 0.14 12.3 2.1 1.4 1 0 0 1 1 1 0 Creb binding DUF726 PF05277.7 EPS33767.1 - 9.3e-95 317.4 12.8 1.9e-87 293.3 0.3 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF726) Abhydrolase_5 PF12695.2 EPS33767.1 - 0.0012 18.6 0.0 0.0024 17.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EPS33767.1 - 0.0025 18.0 0.0 0.0072 16.5 0.0 1.7 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 EPS33767.1 - 0.0035 17.2 0.0 0.0064 16.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 EPS33767.1 - 0.042 13.5 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 Cutinase DUF900 PF05990.7 EPS33767.1 - 0.044 13.0 0.4 0.091 12.0 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Gly-zipper_OmpA PF13436.1 EPS33767.1 - 0.067 12.8 0.8 0.22 11.2 0.6 1.9 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain ADH_zinc_N_2 PF13602.1 EPS33768.1 - 5.2e-23 82.3 0.1 1.5e-22 80.8 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EPS33768.1 - 1.7e-15 56.7 0.0 2.9e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPS33768.1 - 1.4e-05 24.7 0.1 0.0018 18.0 0.0 3.2 2 2 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EPS33768.1 - 0.02 14.4 0.1 0.039 13.5 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Sulfatase PF00884.18 EPS33769.1 - 9.3e-62 208.9 1.1 1.2e-61 208.6 0.7 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EPS33769.1 - 0.00086 18.7 3.5 0.004 16.5 2.5 1.8 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EPS33769.1 - 0.013 13.9 0.2 0.042 12.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF229) Glyco_hydro_75 PF07335.6 EPS33771.1 - 4.8e-46 156.4 0.1 7.8e-46 155.7 0.1 1.3 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 Ribosomal_L33 PF00471.15 EPS33772.1 - 0.00019 21.5 0.0 0.00026 21.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 DUF2883 PF11097.3 EPS33773.1 - 0.066 13.3 0.1 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2883) Reo_sigmaC PF04582.7 EPS33773.1 - 3.3 6.7 26.3 0.81 8.8 0.1 4.4 2 1 3 5 5 5 0 Reovirus sigma C capsid protein Pkinase PF00069.20 EPS33774.1 - 1.2e-60 204.8 0.0 1.7e-60 204.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS33774.1 - 3e-33 115.0 0.0 3.9e-33 114.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPS33774.1 - 3.1e-06 26.3 0.0 5.1e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EPS33774.1 - 0.001 18.8 0.2 0.001 18.8 0.1 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EPS33774.1 - 0.011 14.7 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF605 PF04652.11 EPS33774.1 - 0.086 12.2 12.3 0.12 11.7 8.5 1.1 1 0 0 1 1 1 0 Vta1 like Cellulase PF00150.13 EPS33775.1 - 2e-14 53.4 3.7 2e-14 53.4 2.6 1.7 1 1 1 2 2 2 1 Cellulase (glycosyl hydrolase family 5) DUF3357 PF11837.3 EPS33775.1 - 0.046 13.5 0.4 0.24 11.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) Response_reg PF00072.19 EPS33776.1 - 3.3e-18 65.7 0.0 7.6e-18 64.5 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 EPS33776.1 - 4.2e-17 61.8 0.0 8.5e-17 60.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EPS33776.1 - 7.6e-14 51.4 0.7 2.1e-13 50.0 0.5 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.6 EPS33776.1 - 7.4e-05 23.1 0.0 0.00022 21.6 0.0 1.8 1 0 0 1 1 1 1 PAS fold PHY PF00360.15 EPS33776.1 - 0.00024 20.2 0.0 0.0014 17.7 0.0 2.1 2 1 1 3 3 3 1 Phytochrome region HATPase_c_2 PF13581.1 EPS33776.1 - 0.0073 16.0 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain SNF2_N PF00176.18 EPS33778.1 - 1e-74 251.0 0.1 2.7e-74 249.6 0.0 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPS33778.1 - 9.3e-11 41.4 0.0 2.7e-10 39.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PP2C_C PF07830.8 EPS33778.1 - 0.27 11.3 4.6 3.9 7.6 0.0 3.7 3 0 0 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain SIR2 PF02146.12 EPS33779.1 - 2e-39 135.1 0.0 5.4e-39 133.7 0.0 1.6 1 1 0 1 1 1 1 Sir2 family Dynamin_N PF00350.18 EPS33780.1 - 3.1e-29 101.9 0.3 1.1e-28 100.1 0.0 2.1 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 EPS33780.1 - 9.4e-15 54.1 0.1 2e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region Miro PF08477.8 EPS33780.1 - 0.00064 20.2 0.0 0.0016 18.8 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EPS33780.1 - 0.0022 17.9 0.0 0.014 15.3 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase GED PF02212.13 EPS33780.1 - 0.0041 16.9 0.4 0.0041 16.9 0.3 3.9 4 2 0 4 4 4 1 Dynamin GTPase effector domain AAA_21 PF13304.1 EPS33780.1 - 0.12 12.2 0.0 0.37 10.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain Pyridox_ox_2 PF12900.2 EPS33781.1 - 2.8e-38 130.9 0.0 3.7e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Peptidase_M24 PF00557.19 EPS33782.1 - 1.6e-48 165.0 0.0 2.4e-48 164.4 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EPS33782.1 - 8.1e-37 125.6 0.0 1.5e-36 124.7 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Dfp1_Him1_M PF08630.5 EPS33783.1 - 2e-41 140.7 0.0 4.2e-41 139.6 0.0 1.6 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 EPS33783.1 - 4.8e-24 83.7 1.6 8.2e-24 83.0 0.3 2.0 2 0 0 2 2 2 1 DBF zinc finger PTCB-BRCT PF12738.2 EPS33783.1 - 0.0031 17.3 0.0 0.0086 15.9 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain Ank_2 PF12796.2 EPS33784.1 - 3.7e-40 136.1 0.0 2e-12 47.2 0.0 6.4 4 1 2 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPS33784.1 - 1.6e-29 101.7 4.1 2.1e-10 40.8 0.0 9.2 8 2 2 10 10 10 5 Ankyrin repeats (many copies) Ank PF00023.25 EPS33784.1 - 2.2e-25 87.1 12.3 0.00023 20.8 0.0 11.7 11 1 0 11 11 11 5 Ankyrin repeat Pkinase PF00069.20 EPS33784.1 - 5.9e-25 87.8 0.0 9.6e-25 87.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Ank_5 PF13857.1 EPS33784.1 - 9.9e-25 86.0 6.5 7.2e-08 32.4 0.0 7.9 5 2 2 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPS33784.1 - 4.8e-21 72.7 0.9 0.0056 16.8 0.0 10.9 12 0 0 12 12 12 4 Ankyrin repeat Pkinase_Tyr PF07714.12 EPS33784.1 - 8.1e-15 54.5 0.0 1.3e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPS33784.1 - 0.18 10.7 0.0 0.3 9.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like HeLo PF14479.1 EPS33785.1 - 2.3e-17 63.4 1.7 4.1e-17 62.6 1.2 1.4 1 0 0 1 1 1 1 Prion-inhibition and propagation Pkinase_Tyr PF07714.12 EPS33785.1 - 0.00092 18.3 0.0 0.0086 15.1 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EPS33785.1 - 0.07 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain CpcD PF01383.16 EPS33785.1 - 0.17 12.0 1.8 1.6 8.9 0.1 2.4 2 0 0 2 2 2 0 CpcD/allophycocyanin linker domain Pantoate_transf PF02548.10 EPS33786.1 - 1.2e-104 349.1 0.1 1.3e-104 348.9 0.1 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 EPS33786.1 - 6.7e-08 32.0 0.1 1.2e-07 31.1 0.1 1.5 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase PA PF02225.17 EPS33786.1 - 0.071 12.8 0.3 3.2 7.4 0.1 2.8 3 0 0 3 3 3 0 PA domain APG12 PF04110.8 EPS33787.1 - 2.5e-29 101.2 0.0 3.8e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 EPS33787.1 - 0.055 13.4 0.0 0.073 13.0 0.0 1.2 1 0 0 1 1 1 0 Autophagy protein Atg8 ubiquitin like UQ_con PF00179.21 EPS33788.1 - 5.1e-35 119.9 0.1 6.3e-35 119.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme LAMTOR PF15454.1 EPS33789.1 - 7.9e-23 80.5 0.6 1.6e-22 79.6 0.4 1.5 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator KAR9 PF08580.5 EPS33789.1 - 0.21 9.8 2.9 0.23 9.6 2.0 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF2011 PF09428.5 EPS33790.1 - 1.8e-40 137.8 8.7 2.4e-40 137.4 6.0 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) Tht1 PF04163.7 EPS33791.1 - 0.00036 19.0 20.3 0.012 14.0 12.8 2.9 2 1 0 2 2 2 1 Tht1-like nuclear fusion protein DUF2400 PF09674.5 EPS33791.1 - 5.2 6.6 9.8 1.3 8.7 2.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2400) Plasmid_killer PF05015.8 EPS33791.1 - 5.6 7.1 6.9 1.2 9.2 1.0 2.6 2 1 1 3 3 3 0 Plasmid maintenance system killer protein APH PF01636.18 EPS33792.1 - 6.5e-10 39.1 0.0 5.2e-09 36.1 0.0 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family Ferric_reduct PF01794.14 EPS33793.1 - 2.3e-21 76.1 9.7 2.3e-21 76.1 6.7 2.4 2 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EPS33793.1 - 3.3e-13 49.8 0.0 4.8e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EPS33793.1 - 2.7e-09 36.8 0.0 6e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EPS33793.1 - 3.1e-05 24.4 0.0 0.0002 21.8 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Ctr PF04145.10 EPS33794.1 - 1.3e-36 125.8 2.7 1.6e-36 125.4 1.9 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Ribosomal_L6 PF00347.18 EPS33795.1 - 5.1e-26 90.9 0.0 1.2e-13 51.3 0.0 3.1 2 1 0 2 2 2 2 Ribosomal protein L6 Inositol_P PF00459.20 EPS33796.1 - 1.4e-52 178.6 2.5 6e-52 176.5 1.7 1.8 1 1 0 1 1 1 1 Inositol monophosphatase family S_layer_C PF05124.7 EPS33796.1 - 0.086 12.4 0.0 0.26 10.8 0.0 1.7 2 0 0 2 2 2 0 S-layer like family, C-terminal region VHS PF00790.14 EPS33797.1 - 2.6e-25 88.7 0.0 7.1e-25 87.2 0.0 1.7 2 1 1 3 3 3 1 VHS domain GAT PF03127.9 EPS33797.1 - 1.6e-09 37.6 0.3 3.4e-09 36.5 0.2 1.6 1 0 0 1 1 1 1 GAT domain ENTH PF01417.15 EPS33797.1 - 0.00073 19.3 0.0 0.0041 16.9 0.0 2.0 2 0 0 2 2 2 1 ENTH domain Ribosomal_60s PF00428.14 EPS33797.1 - 4 7.9 6.4 1.2 9.5 0.7 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein ABM PF03992.11 EPS33798.1 - 0.00032 20.6 0.6 0.013 15.5 0.0 2.5 2 1 0 2 2 2 2 Antibiotic biosynthesis monooxygenase Flavoprotein PF02441.14 EPS33799.1 - 4.9e-10 39.1 0.1 8.9e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 Flavoprotein MFS_1 PF07690.11 EPS33800.1 - 2.1e-44 151.6 46.2 2.1e-44 151.6 32.0 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS33800.1 - 4.9e-18 64.9 11.2 4.9e-18 64.9 7.8 3.2 3 1 0 3 3 3 1 Sugar (and other) transporter GMC_oxred_N PF00732.14 EPS33801.1 - 1e-60 205.4 0.0 1.4e-60 204.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EPS33801.1 - 9.7e-28 97.2 0.0 1.9e-27 96.3 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EPS33801.1 - 9.8e-09 34.5 0.0 8.9e-05 21.5 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPS33801.1 - 4.8e-07 28.9 0.0 0.00097 18.0 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EPS33801.1 - 5.6e-06 26.2 0.0 1.4e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EPS33801.1 - 0.00032 19.7 0.0 0.00048 19.1 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EPS33801.1 - 0.0011 18.9 0.0 0.0081 16.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPS33801.1 - 0.0074 16.6 0.0 0.15 12.5 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPS33801.1 - 0.0082 16.2 0.0 5.2 7.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPS33801.1 - 0.011 14.8 0.6 0.027 13.5 0.1 1.8 2 0 0 2 2 2 0 Thi4 family NADHdh_A3 PF14987.1 EPS33801.1 - 0.014 15.2 0.0 0.052 13.4 0.0 1.9 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 HI0933_like PF03486.9 EPS33801.1 - 0.018 13.4 0.0 0.052 12.0 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein Trp_halogenase PF04820.9 EPS33801.1 - 0.034 12.7 0.0 0.049 12.2 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.1 EPS33801.1 - 0.057 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EPS33801.1 - 0.075 12.0 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_binding_4 PF01565.18 EPS33802.1 - 4.1e-19 68.4 3.4 9.1e-19 67.3 2.4 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EPS33802.1 - 3.4e-11 42.8 0.2 6e-11 42.0 0.2 1.4 1 0 0 1 1 1 1 Berberine and berberine like UbiA PF01040.13 EPS33803.1 - 1.2e-17 64.0 11.4 1.9e-17 63.3 7.9 1.3 1 1 0 1 1 1 1 UbiA prenyltransferase family p450 PF00067.17 EPS33804.1 - 1.1e-44 152.7 0.0 1.3e-44 152.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 EPS33805.1 - 1.7e-23 83.3 1.5 2.5e-23 82.8 1.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPS33805.1 - 6.2e-13 48.7 0.3 1.9e-12 47.2 0.2 1.7 1 1 1 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 EPS33805.1 - 1.5e-07 30.6 0.1 1.9e-07 30.2 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EPS33805.1 - 1.7e-07 30.9 0.1 3.6e-07 29.8 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EPS33805.1 - 5.5e-05 23.0 0.1 7.3e-05 22.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EPS33805.1 - 0.00012 22.1 0.4 0.00018 21.6 0.3 1.3 1 0 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 EPS33805.1 - 0.00034 20.7 0.0 0.00056 20.0 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase ApbA PF02558.11 EPS33805.1 - 0.0052 16.2 0.5 0.0083 15.5 0.4 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Methyltransf_25 PF13649.1 EPS33805.1 - 0.013 15.8 0.0 0.023 15.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Eno-Rase_NADH_b PF12242.3 EPS33805.1 - 0.043 13.5 0.4 0.096 12.4 0.3 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ThiF PF00899.16 EPS33805.1 - 0.24 11.2 1.5 0.97 9.2 0.3 2.0 1 1 1 2 2 2 0 ThiF family DUF202 PF02656.10 EPS33806.1 - 0.92 9.7 10.4 8.8 6.6 0.8 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Tannase PF07519.6 EPS33808.1 - 8.9e-118 393.9 0.7 1.2e-117 393.5 0.5 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 EPS33808.1 - 2.3e-05 24.1 0.0 0.048 13.4 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPS33808.1 - 0.0043 16.9 0.0 0.0087 15.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPS33808.1 - 0.0077 15.8 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EPS33808.1 - 0.11 11.6 1.7 0.13 11.4 0.1 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family Tannase PF07519.6 EPS33810.1 - 6.1e-134 447.2 3.5 7.6e-134 446.9 2.4 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Phosphoprotein PF00922.12 EPS33811.1 - 3 6.9 7.2 5.4 6.1 5.0 1.4 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein MFS_1 PF07690.11 EPS33812.1 - 1e-21 77.0 51.4 1e-21 77.0 35.6 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Gpi16 PF04113.9 EPS33814.1 - 2.8e-247 821.2 0.0 3.5e-247 820.9 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component LUC7 PF03194.10 EPS33815.1 - 3.5e-73 246.2 0.2 4.3e-73 245.9 0.2 1.0 1 0 0 1 1 1 1 LUC7 N_terminus BLVR PF06375.6 EPS33816.1 - 0.0066 16.2 8.5 0.0071 16.1 5.9 1.1 1 0 0 1 1 1 1 Bovine leukaemia virus receptor (BLVR) CENP-N PF05238.8 EPS33816.1 - 0.027 13.5 1.4 0.031 13.3 1.0 1.0 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Rtf2 PF04641.7 EPS33816.1 - 0.035 13.2 3.7 0.036 13.2 2.6 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger Cnd1_N PF12922.2 EPS33816.1 - 0.079 12.5 0.9 0.086 12.4 0.6 1.1 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term DUF3899 PF13038.1 EPS33816.1 - 0.095 12.8 0.5 0.12 12.5 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) Med19 PF10278.4 EPS33816.1 - 0.12 12.0 8.0 0.13 11.9 5.6 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Bap31 PF05529.7 EPS33816.1 - 0.13 11.7 0.7 0.14 11.5 0.5 1.0 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like RNase_H2-Ydr279 PF09468.5 EPS33816.1 - 0.13 11.3 4.3 0.12 11.5 3.0 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Peptidase_S49_N PF08496.5 EPS33816.1 - 0.14 11.9 4.7 0.14 11.9 3.3 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Rrn6 PF10214.4 EPS33816.1 - 0.15 10.1 4.9 0.16 10.0 3.4 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Protocadherin PF08374.6 EPS33816.1 - 1.6 8.3 5.0 1.7 8.2 3.4 1.1 1 0 0 1 1 1 0 Protocadherin TFIIS_M PF07500.9 EPS33817.1 - 8.8e-25 87.0 0.1 2.1e-24 85.8 0.1 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.8 EPS33817.1 - 8e-21 74.7 0.0 2e-20 73.4 0.0 1.7 1 0 0 1 1 1 1 SPOC domain PHD PF00628.24 EPS33817.1 - 2.3e-10 40.0 14.0 4.8e-10 38.9 9.7 1.6 1 0 0 1 1 1 1 PHD-finger PHD_3 PF13922.1 EPS33817.1 - 0.0063 16.7 0.8 0.024 14.8 0.6 2.0 1 0 0 1 1 1 1 PHD domain of transcriptional enhancer, Asx PHD_2 PF13831.1 EPS33817.1 - 1.6 8.1 10.2 0.41 9.9 4.9 1.6 2 0 0 2 2 2 0 PHD-finger Relaxase PF03432.9 EPS33818.1 - 0.16 11.3 1.9 0.27 10.5 0.0 1.9 2 0 0 2 2 2 0 Relaxase/Mobilisation nuclease domain PspB PF06667.7 EPS33818.1 - 1.8 8.5 4.2 5 7.1 0.1 2.5 2 0 0 2 2 2 0 Phage shock protein B FF PF01846.14 EPS33819.1 - 7.5e-13 48.2 9.1 7.5e-10 38.6 0.2 3.5 3 0 0 3 3 3 3 FF domain WW PF00397.21 EPS33819.1 - 4.8e-09 35.9 3.2 1.2e-08 34.6 0.8 2.7 2 0 0 2 2 2 1 WW domain Proteasome PF00227.21 EPS33820.1 - 1.2e-61 207.2 0.1 1.5e-61 207.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EPS33820.1 - 3.2e-14 51.9 0.4 7.1e-14 50.8 0.1 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Pkinase PF00069.20 EPS33824.1 - 3.3e-31 108.3 0.0 5.9e-30 104.2 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS33824.1 - 1.1e-07 31.2 0.1 0.0041 16.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase 2H-phosphodiest PF08975.5 EPS33824.1 - 0.038 13.7 0.0 0.08 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1868) Acyl-CoA_dh_1 PF00441.19 EPS33825.1 - 3e-33 115.0 0.8 3e-33 115.0 0.5 1.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EPS33825.1 - 5.9e-20 70.5 1.4 1e-19 69.7 1.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EPS33825.1 - 2.1e-12 47.5 0.1 1.3e-11 45.0 0.0 2.4 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EPS33825.1 - 2.5e-07 30.9 0.4 3.7e-07 30.4 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain FAD_binding_1 PF00667.15 EPS33826.1 - 2.3e-59 200.5 0.0 3.6e-59 199.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EPS33826.1 - 4e-11 43.4 0.0 1.2e-10 41.9 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain POR PF01558.13 EPS33826.1 - 2.7e-07 30.6 0.2 8.3e-07 29.0 0.1 1.8 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.15 EPS33826.1 - 0.0059 16.5 0.1 0.022 14.7 0.1 1.9 1 0 0 1 1 1 1 Transketolase, C-terminal domain FtsJ PF01728.14 EPS33827.1 - 8.5e-63 211.6 0.0 1.2e-62 211.1 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 EPS33827.1 - 0.0028 18.2 0.0 0.046 14.3 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain DEAD PF00270.24 EPS33828.1 - 2.4e-43 147.5 0.1 6.6e-43 146.1 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPS33828.1 - 6e-22 77.3 0.0 1.5e-21 75.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EPS33828.1 - 0.027 13.2 0.0 0.04 12.6 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain DUF1253 PF06862.7 EPS33828.1 - 0.048 12.0 0.0 1.2 7.4 0.0 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1253) 4HBT PF03061.17 EPS33829.1 - 3.6e-08 33.4 0.0 7.3e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily HECT PF00632.20 EPS33830.1 - 2.8e-81 273.1 0.0 4.7e-81 272.3 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HEAT PF02985.17 EPS33830.1 - 0.015 15.2 4.0 1.9 8.7 0.0 5.2 7 0 0 7 7 7 0 HEAT repeat Response_reg PF00072.19 EPS33832.1 - 3.5e-24 84.9 0.2 6.9e-24 84.0 0.1 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 EPS33832.1 - 1.3e-21 76.4 0.0 2.8e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EPS33832.1 - 1.9e-13 50.1 0.1 5.9e-13 48.6 0.0 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_2 PF13581.1 EPS33832.1 - 0.072 12.8 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain HATPase_c_5 PF14501.1 EPS33832.1 - 0.13 11.9 0.0 0.36 10.5 0.0 1.7 1 0 0 1 1 1 0 GHKL domain CTP_transf_2 PF01467.21 EPS33833.1 - 1.3e-28 100.0 0.0 1.7e-28 99.6 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase SIS PF01380.17 EPS33834.1 - 1.9e-12 46.8 0.0 2.3e-11 43.4 0.0 2.2 2 0 0 2 2 2 1 SIS domain SIS_2 PF13580.1 EPS33834.1 - 1.6e-07 31.1 0.0 4.7e-05 23.1 0.0 2.3 1 1 1 2 2 2 2 SIS domain Ubie_methyltran PF01209.13 EPS33835.1 - 3.8e-82 274.8 0.0 5e-82 274.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EPS33835.1 - 7.5e-15 54.8 0.0 1e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPS33835.1 - 1.4e-13 51.1 0.0 2.6e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPS33835.1 - 2.9e-12 46.8 0.0 8.5e-12 45.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPS33835.1 - 1.1e-10 41.4 0.0 1.8e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPS33835.1 - 1.3e-10 41.6 0.0 2.2e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS33835.1 - 2.5e-07 31.2 0.0 4.9e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPS33835.1 - 1.6e-05 24.8 0.0 3.6e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EPS33835.1 - 0.014 15.0 0.0 0.22 11.0 0.0 2.5 3 0 0 3 3 3 0 Hypothetical methyltransferase DUF3649 PF12365.3 EPS33835.1 - 2.7 7.5 4.8 1.1 8.8 1.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3649) Pkinase PF00069.20 EPS33836.1 - 1.3e-06 27.8 0.0 1.5e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS33836.1 - 0.00038 19.6 0.0 0.00049 19.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPS33836.1 - 0.13 12.0 0.1 0.18 11.5 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Gly_transf_sug PF04488.10 EPS33837.1 - 5.9e-10 39.4 0.0 1.1e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Glycophorin_A PF01102.13 EPS33839.1 - 0.00012 21.8 5.5 0.00019 21.1 3.5 1.5 1 1 0 1 1 1 1 Glycophorin A Pex14_N PF04695.8 EPS33839.1 - 0.0015 18.5 3.1 0.0024 17.9 2.2 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region RskA PF10099.4 EPS33839.1 - 0.0023 17.6 0.2 0.0034 17.1 0.1 1.3 1 0 0 1 1 1 1 Anti-sigma-K factor rskA SKG6 PF08693.5 EPS33839.1 - 0.0032 16.7 0.3 0.0074 15.5 0.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EphA2_TM PF14575.1 EPS33839.1 - 0.0057 17.0 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.10 EPS33839.1 - 0.0071 15.8 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 PRCC PF10253.4 EPS33839.1 - 0.01 16.5 2.0 0.014 16.0 1.4 1.2 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting DUF3042 PF11240.3 EPS33839.1 - 0.021 14.6 0.4 0.036 13.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) BatD PF13584.1 EPS33839.1 - 0.022 13.3 0.1 0.029 12.9 0.0 1.1 1 0 0 1 1 1 0 Oxygen tolerance TMEM154 PF15102.1 EPS33839.1 - 0.026 14.2 1.1 0.042 13.5 0.4 1.6 1 1 0 1 1 1 0 TMEM154 protein family Amnionless PF14828.1 EPS33839.1 - 0.037 12.5 0.0 0.044 12.2 0.0 1.1 1 0 0 1 1 1 0 Amnionless DUF4366 PF14283.1 EPS33839.1 - 0.038 13.3 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Syndecan PF01034.15 EPS33839.1 - 0.083 12.5 0.2 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain FAM75 PF14650.1 EPS33839.1 - 0.09 12.1 7.9 0.15 11.4 5.5 1.2 1 0 0 1 1 1 0 FAM75 family Plasmodium_Vir PF05795.6 EPS33839.1 - 0.098 11.8 0.1 0.12 11.5 0.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SCF PF02404.10 EPS33839.1 - 0.17 11.0 0.9 0.22 10.6 0.7 1.1 1 0 0 1 1 1 0 Stem cell factor DUF2207 PF09972.4 EPS33839.1 - 0.17 10.4 0.0 0.24 9.9 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MSA-2c PF12238.3 EPS33839.1 - 3.8 7.1 8.9 1.5 8.4 4.4 1.5 2 0 0 2 2 2 0 Merozoite surface antigen 2c APH PF01636.18 EPS33840.1 - 8.9e-20 71.4 0.1 1.2e-19 71.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPS33840.1 - 0.002 17.7 0.0 0.0036 16.9 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EPS33840.1 - 0.054 12.8 0.0 0.25 10.6 0.0 1.9 2 0 0 2 2 2 0 RIO1 family EcKinase PF02958.15 EPS33840.1 - 0.072 12.2 0.0 0.16 11.0 0.0 1.5 1 1 1 2 2 2 0 Ecdysteroid kinase Y_phosphatase3 PF13350.1 EPS33841.1 - 5e-41 140.6 0.0 6.9e-41 140.2 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EPS33841.1 - 1e-11 44.7 0.1 6.7e-10 38.9 0.1 2.5 2 1 0 2 2 2 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 EPS33841.1 - 0.0016 17.7 0.0 0.0024 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 EPS33841.1 - 0.0019 17.6 0.0 0.003 16.9 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EPS33841.1 - 0.0059 16.6 0.0 0.0098 15.9 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Glyco_hydro_2 PF00703.16 EPS33842.1 - 6.7e-07 29.7 0.0 2.9e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 EPS33842.1 - 0.0097 14.8 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain E1_dh PF00676.15 EPS33844.1 - 6.4e-89 297.6 0.0 8e-89 297.3 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 EPS33844.1 - 3.1e-05 23.6 0.2 0.00069 19.2 0.0 2.5 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 EPS33844.1 - 0.031 13.2 0.0 0.19 10.6 0.0 2.1 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase XFP_N PF09364.5 EPS33844.1 - 0.035 12.6 0.0 0.056 11.9 0.0 1.3 1 0 0 1 1 1 0 XFP N-terminal domain Rieske PF00355.21 EPS33845.1 - 1.1e-09 37.7 0.0 1.7e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 EPS33845.1 - 0.00036 20.2 0.0 0.00055 19.6 0.0 1.2 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain zf-RING_4 PF14570.1 EPS33846.1 - 2.3e-19 68.7 13.9 3.9e-19 67.9 9.7 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 EPS33846.1 - 1.9e-05 24.2 6.7 3.3e-05 23.4 4.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.17 EPS33846.1 - 5.4e-05 22.7 0.0 0.00012 21.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Baculo_IE-1 PF05290.6 EPS33846.1 - 0.0009 18.9 4.7 0.0015 18.2 3.3 1.3 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) RRM_5 PF13893.1 EPS33846.1 - 0.0018 18.1 0.0 0.0038 17.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rtf2 PF04641.7 EPS33846.1 - 0.0025 17.0 1.7 0.0025 17.0 1.2 3.4 4 0 0 4 4 4 1 Rtf2 RING-finger zf-C3HC4 PF00097.20 EPS33846.1 - 0.2 11.3 12.7 0.38 10.4 8.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPS33846.1 - 1.3 9.1 11.9 2.3 8.2 8.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Complex1_30kDa PF00329.14 EPS33847.1 - 7.1e-36 122.5 0.0 1e-35 122.0 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit BUD22 PF09073.5 EPS33848.1 - 8.8e-102 341.3 18.2 1.1e-101 341.1 12.6 1.1 1 0 0 1 1 1 1 BUD22 Daxx PF03344.10 EPS33848.1 - 2.3 6.6 18.1 4.2 5.7 12.5 1.3 1 0 0 1 1 1 0 Daxx Family Fungal_trans PF04082.13 EPS33849.1 - 2.4e-27 95.4 0.1 4.1e-27 94.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS33849.1 - 6.6e-06 25.9 9.5 1.3e-05 24.9 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Flavi_NS5 PF00972.15 EPS33849.1 - 0.062 11.1 0.0 0.091 10.6 0.0 1.1 1 0 0 1 1 1 0 Flavivirus RNA-directed RNA polymerase OCD_Mu_crystall PF02423.10 EPS33850.1 - 7.7e-10 38.0 0.0 7.8e-09 34.7 0.0 2.0 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 EPS33850.1 - 0.00017 21.6 0.0 0.0007 19.6 0.0 2.0 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Proteasome_A_N PF10584.4 EPS33850.1 - 0.038 13.3 0.0 0.099 11.9 0.0 1.7 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature Pro_dh PF01619.13 EPS33851.1 - 6.1e-33 114.1 0.3 9e-33 113.5 0.2 1.3 1 0 0 1 1 1 1 Proline dehydrogenase Aldedh PF00171.17 EPS33852.1 - 1.3e-109 366.6 0.3 1.6e-109 366.3 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF4322 PF14210.1 EPS33852.1 - 0.1 12.0 0.0 0.3 10.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4322) AP_endonuc_2 PF01261.19 EPS33853.1 - 2.3e-35 121.8 0.0 3e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel 6PGD PF00393.14 EPS33854.1 - 5.1e-63 212.9 0.0 6.9e-63 212.5 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EPS33854.1 - 3.1e-35 121.4 0.0 1.7e-34 119.0 0.0 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EPS33854.1 - 2.5e-06 27.2 0.1 4.8e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EPS33854.1 - 0.00086 19.0 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 EPS33854.1 - 0.0017 17.7 0.1 0.0039 16.5 0.1 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 EPS33854.1 - 0.0019 17.3 0.2 0.0048 16.0 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 EPS33854.1 - 0.011 15.1 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_11 PF14833.1 EPS33854.1 - 0.015 15.3 0.0 0.041 13.9 0.0 1.8 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase OCD_Mu_crystall PF02423.10 EPS33854.1 - 0.073 11.8 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.12 EPS33854.1 - 0.094 13.1 0.0 0.26 11.7 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent PNP_UDP_1 PF01048.15 EPS33855.1 - 4.6e-38 130.5 0.2 5.5e-38 130.2 0.2 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily DUF747 PF05346.6 EPS33856.1 - 2.6e-129 431.0 2.0 4.6e-129 430.2 1.4 1.4 1 0 0 1 1 1 1 Eukaryotic membrane protein family Oxidored_FMN PF00724.15 EPS33858.1 - 3.6e-70 236.6 0.0 4.2e-70 236.4 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 EPS33858.1 - 0.0075 15.1 0.1 0.07 11.9 0.0 2.1 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) p450 PF00067.17 EPS33859.1 - 7.4e-75 252.2 0.0 9.4e-75 251.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SARG PF15385.1 EPS33860.1 - 0.13 11.5 7.7 0.15 11.3 5.3 1.1 1 0 0 1 1 1 0 Specifically androgen-regulated gene protein Nucleo_P87 PF07267.6 EPS33860.1 - 2.1 6.9 4.0 2.3 6.7 2.8 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Pilus_PilP PF11356.3 EPS33860.1 - 2.9 8.1 5.7 18 5.6 3.6 2.3 1 1 0 1 1 1 0 Type IV pilus biogenesis WGG PF10273.4 EPS33861.1 - 1.5e-30 105.0 0.2 1.5e-30 105.0 0.1 1.6 2 0 0 2 2 2 1 Pre-rRNA-processing protein TSR2 GTP_EFTU PF00009.22 EPS33862.1 - 2.1e-40 138.1 0.0 3.7e-40 137.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EPS33862.1 - 1.4e-19 70.0 0.0 3.5e-19 68.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EPS33862.1 - 2.8e-05 24.1 0.0 7e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EPS33862.1 - 0.02 14.8 0.0 0.048 13.6 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase G-alpha PF00503.15 EPS33862.1 - 0.046 12.4 0.5 0.092 11.4 0.0 1.6 2 0 0 2 2 2 0 G-protein alpha subunit Ran-binding PF05508.6 EPS33863.1 - 1.3e-115 385.5 0.4 1.7e-115 385.0 0.3 1.2 1 0 0 1 1 1 1 RanGTP-binding protein BSD PF03909.12 EPS33864.1 - 8.5e-16 57.4 0.7 1.8e-15 56.4 0.5 1.6 1 0 0 1 1 1 1 BSD domain Suf PF05843.9 EPS33864.1 - 0.055 13.2 2.3 0.11 12.2 1.6 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Rad4 PF03835.10 EPS33866.1 - 4.2e-34 117.0 0.6 1.3e-33 115.4 0.4 1.9 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 EPS33866.1 - 1.7e-29 101.3 0.1 4.8e-29 99.8 0.0 1.8 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 EPS33866.1 - 7e-23 79.9 0.0 1.7e-22 78.7 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EPS33866.1 - 9.2e-17 61.1 0.6 4.1e-16 59.0 0.4 2.3 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 EPS33866.1 - 0.033 14.3 0.0 0.18 11.9 0.0 2.3 1 1 0 1 1 1 0 Transglutaminase-like superfamily Gag_p30 PF02093.11 EPS33866.1 - 0.11 11.6 1.8 7.6 5.6 0.0 3.0 3 0 0 3 3 3 0 Gag P30 core shell protein C8 PF08742.6 EPS33867.1 - 0.11 12.7 0.1 0.48 10.6 0.0 2.0 2 0 0 2 2 2 0 C8 domain Methyltransf_23 PF13489.1 EPS33868.1 - 7.8e-19 67.9 0.0 1.3e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS33868.1 - 8e-10 39.2 0.0 1.8e-08 34.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPS33868.1 - 2.4e-09 36.9 0.0 1.1e-08 34.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPS33868.1 - 3.6e-07 30.5 0.0 6.5e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPS33868.1 - 2.1e-06 28.0 0.0 8.2e-06 26.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPS33868.1 - 0.00032 21.0 0.0 0.00076 19.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EPS33868.1 - 0.00057 19.1 0.0 0.001 18.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 EPS33868.1 - 0.0019 17.6 0.0 0.003 17.0 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 EPS33868.1 - 0.0051 16.8 0.0 0.014 15.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EPS33868.1 - 0.0054 15.8 0.0 0.01 14.9 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 EPS33868.1 - 0.0066 15.5 0.0 0.031 13.3 0.0 1.9 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EPS33868.1 - 0.033 13.5 0.0 0.068 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_24 PF13578.1 EPS33868.1 - 0.14 12.9 0.0 0.6 10.9 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Proteasome PF00227.21 EPS33870.1 - 4.4e-44 150.0 0.1 5.4e-44 149.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 EPS33870.1 - 6.9e-14 50.8 0.1 1.6e-13 49.6 0.1 1.6 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Reo_sigmaC PF04582.7 EPS33871.1 - 0.0013 18.0 3.0 0.0024 17.0 2.1 1.4 1 0 0 1 1 1 1 Reovirus sigma C capsid protein Prefoldin_2 PF01920.15 EPS33871.1 - 0.14 11.9 0.3 5.7 6.7 0.0 3.0 3 0 0 3 3 3 0 Prefoldin subunit Baculo_PEP_C PF04513.7 EPS33871.1 - 0.14 11.9 3.2 0.86 9.4 2.1 2.1 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Spc7 PF08317.6 EPS33871.1 - 1.4 7.4 2.9 1.5 7.3 0.3 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein KH_1 PF00013.24 EPS33873.1 - 4.3e-42 141.5 3.5 3.2e-16 58.7 0.2 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EPS33873.1 - 3.2e-31 106.4 10.6 5e-11 41.9 1.4 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EPS33873.1 - 4e-12 45.5 3.4 0.0043 16.5 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EPS33873.1 - 0.00012 21.6 0.6 2.7 7.7 0.0 3.4 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 EPS33873.1 - 0.0023 17.6 5.6 0.99 9.2 0.1 3.2 3 0 0 3 3 3 2 NusA-like KH domain RRF_GI PF12614.3 EPS33874.1 - 0.021 14.6 6.6 0.48 10.2 0.1 3.0 3 0 0 3 3 3 0 Ribosome recycling factor DUF3510 PF12022.3 EPS33874.1 - 0.041 14.0 0.4 0.1 12.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3510) DivIC PF04977.10 EPS33874.1 - 0.073 12.5 0.2 0.073 12.5 0.1 3.3 2 1 1 3 3 3 0 Septum formation initiator CENP-K PF11802.3 EPS33874.1 - 0.087 12.0 4.5 0.61 9.2 0.0 2.9 3 0 0 3 3 3 0 Centromere-associated protein K DUF2422 PF10337.4 EPS33874.1 - 0.094 11.4 2.6 0.088 11.5 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2422) IncA PF04156.9 EPS33874.1 - 0.26 10.8 16.5 1.2 8.6 4.4 2.6 2 0 0 2 2 2 0 IncA protein TMF_TATA_bd PF12325.3 EPS33874.1 - 0.41 10.3 11.8 3.8 7.2 3.3 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Exonuc_VII_L PF02601.10 EPS33874.1 - 0.52 9.4 9.2 0.13 11.4 1.1 2.4 1 1 1 2 2 2 0 Exonuclease VII, large subunit ADIP PF11559.3 EPS33874.1 - 0.93 9.3 16.3 0.4 10.5 1.3 2.6 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding FUSC-like PF12805.2 EPS33874.1 - 5.2 5.9 10.2 1.1 8.0 1.4 2.1 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS DEAD PF00270.24 EPS33875.1 - 2.6e-26 92.1 0.1 3.1e-23 82.1 0.0 2.9 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EPS33875.1 - 1.2e-21 76.2 0.0 9.2e-18 63.8 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain RQC PF09382.5 EPS33875.1 - 7.5e-16 57.7 0.0 1.7e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 RQC domain HRDC PF00570.18 EPS33875.1 - 1.9e-09 37.1 0.0 5.3e-09 35.6 0.0 1.8 1 0 0 1 1 1 1 HRDC domain ResIII PF04851.10 EPS33875.1 - 8.9e-05 22.3 0.0 0.00064 19.6 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Kelch_3 PF13415.1 EPS33876.1 - 1.1e-30 104.9 14.7 6.5e-10 38.8 0.0 6.9 7 0 0 7 7 7 4 Galactose oxidase, central domain DUF4110 PF13422.1 EPS33876.1 - 1.9e-27 94.9 2.7 1.9e-27 94.9 1.9 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4110) Kelch_4 PF13418.1 EPS33876.1 - 2e-22 78.6 19.6 1.3e-06 28.0 0.0 6.4 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_2 PF07646.10 EPS33876.1 - 5.4e-15 54.4 9.3 1.6e-05 24.4 0.0 6.1 6 1 0 6 6 6 3 Kelch motif Kelch_6 PF13964.1 EPS33876.1 - 6.1e-15 54.6 8.1 0.0016 18.4 0.2 5.6 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.1 EPS33876.1 - 1.1e-14 54.0 7.3 1.9e-05 24.5 0.0 6.2 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.20 EPS33876.1 - 2.1e-11 43.1 0.8 1.3e-05 24.6 0.1 5.3 5 0 0 5 5 5 2 Kelch motif Pyridoxal_deC PF00282.14 EPS33877.1 - 1.8e-28 99.0 0.0 2.6e-28 98.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.16 EPS33877.1 - 0.00011 21.2 0.0 0.00018 20.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EPS33877.1 - 0.00026 20.2 0.0 0.00043 19.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EPS33877.1 - 0.018 13.8 0.0 0.03 13.0 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Abhydrolase_6 PF12697.2 EPS33878.1 - 4.1e-13 49.7 0.0 6.3e-12 45.8 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPS33878.1 - 6.3e-10 38.9 0.0 1.3e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPS33878.1 - 3.5e-08 33.3 0.0 3.3e-07 30.1 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EPS33878.1 - 0.033 14.0 0.0 0.089 12.6 0.0 1.7 1 0 0 1 1 1 0 Putative lysophospholipase Mon1 PF03164.9 EPS33879.1 - 1.1e-119 399.7 0.0 1.3e-119 399.5 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 IFRD_C PF04836.7 EPS33879.1 - 0.058 13.5 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 Interferon-related protein conserved region Dopey_N PF04118.9 EPS33880.1 - 7.8e-122 405.8 0.1 8.3e-121 402.5 0.0 2.6 2 0 0 2 2 2 1 Dopey, N-terminal zf-HIT PF04438.11 EPS33882.1 - 6.8e-08 32.0 13.4 1.1e-07 31.3 9.3 1.3 1 0 0 1 1 1 1 HIT zinc finger MBOAT PF03062.14 EPS33883.1 - 2.1e-43 148.6 13.6 3.5e-43 147.9 9.4 1.5 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family His_Phos_2 PF00328.17 EPS33884.1 - 8.6e-11 41.7 0.1 1.4e-09 37.7 0.0 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) Oxidored_molyb PF00174.14 EPS33885.1 - 5e-47 159.4 0.0 8.9e-47 158.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EPS33885.1 - 7.3e-24 83.8 5.0 1.2e-23 83.1 3.5 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain SLBB PF10531.4 EPS33885.1 - 0.081 12.8 0.0 2.4 8.0 0.0 2.5 2 0 0 2 2 2 0 SLBB domain Acylphosphatase PF00708.13 EPS33886.1 - 3e-22 78.5 1.5 5.6e-13 48.8 0.1 2.0 1 1 1 2 2 2 2 Acylphosphatase BLUF PF04940.7 EPS33886.1 - 0.0093 15.6 0.1 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Sensors of blue-light using FAD AOX PF01786.12 EPS33887.1 - 1.5e-92 308.7 0.0 1.8e-92 308.4 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase NADH-u_ox-rdase PF10785.4 EPS33887.1 - 0.26 11.5 1.7 3.1 8.1 0.2 2.5 2 1 0 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit KAR9 PF08580.5 EPS33889.1 - 1.8e-142 476.0 0.6 1.8e-142 476.0 0.4 1.5 2 0 0 2 2 2 1 Yeast cortical protein KAR9 DNA_photolyase PF00875.13 EPS33889.1 - 0.077 12.7 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 DNA photolyase DUF2748 PF10871.3 EPS33889.1 - 0.21 9.9 0.0 0.51 8.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2748) Prefoldin PF02996.12 EPS33889.1 - 0.37 10.4 1.4 2.3 7.8 0.1 2.9 2 1 1 3 3 3 0 Prefoldin subunit Acetyltransf_1 PF00583.19 EPS33890.1 - 5.3e-07 29.5 0.0 8.7e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 EPS33890.1 - 3.1e-06 27.3 0.2 5.8e-06 26.5 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EPS33890.1 - 0.00012 22.0 0.0 0.00017 21.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EPS33890.1 - 0.0039 17.3 0.0 0.0062 16.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPS33890.1 - 0.0044 16.7 0.0 0.0082 15.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EPS33890.1 - 0.009 15.9 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EPS33890.1 - 0.02 15.0 0.0 0.045 13.8 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Complex1_LYR PF05347.10 EPS33891.1 - 3e-06 26.9 0.1 4.9e-06 26.2 0.1 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EPS33891.1 - 4.1e-06 26.9 0.1 7.7e-06 26.0 0.1 1.5 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EPS33891.1 - 2.2e-05 24.8 0.0 2.9e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like PMT_C PF11647.3 EPS33891.1 - 0.092 12.3 0.3 0.55 9.8 0.0 2.2 2 1 1 3 3 3 0 C-terminal region of Pasteurella multocida toxin residues 569-1285 Methyltransf_26 PF13659.1 EPS33892.1 - 2.1e-18 66.4 0.0 3e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EPS33892.1 - 0.0027 17.1 0.6 0.45 9.8 0.4 2.2 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EPS33892.1 - 0.089 13.1 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 EPS33892.1 - 0.16 11.0 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase LSM PF01423.17 EPS33893.1 - 9.9e-17 60.2 0.0 1.3e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EPS33893.1 - 0.00059 19.6 0.0 0.00085 19.2 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF2763 PF10961.3 EPS33893.1 - 0.088 13.2 4.6 0.14 12.5 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) zf-C2H2_4 PF13894.1 EPS33894.1 - 5.3e-05 23.2 1.1 0.048 14.0 0.0 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EPS33894.1 - 9.5e-05 22.5 0.7 0.27 11.6 0.2 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EPS33894.1 - 0.022 14.6 0.6 3.9 7.5 0.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EPS33894.1 - 0.029 14.6 0.0 0.073 13.3 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger double domain GTP_EFTU PF00009.22 EPS33895.1 - 1.5e-09 37.5 0.0 2.5e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 EPS33895.1 - 0.028 13.9 0.2 2 7.8 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PRK PF00485.13 EPS33895.1 - 0.55 9.7 2.1 0.56 9.7 0.4 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AD PF09793.4 EPS33896.1 - 6.6e-27 93.1 0.0 9.7e-27 92.6 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain 6PGD PF00393.14 EPS33897.1 - 7.7e-134 445.4 0.0 9.3e-134 445.1 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EPS33897.1 - 1.1e-52 178.2 0.0 1.5e-52 177.6 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EPS33897.1 - 0.032 14.2 0.0 0.079 13.0 0.0 1.7 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EPS33897.1 - 0.15 12.5 0.0 0.3 11.5 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EPS33897.1 - 0.17 11.0 0.0 0.32 10.1 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RRM_1 PF00076.17 EPS33899.1 - 2.2e-16 59.2 0.0 3.5e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS33899.1 - 1.8e-11 43.8 0.0 4.1e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS33899.1 - 0.00082 19.1 0.0 0.0018 18.0 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAT1 PF09770.4 EPS33899.1 - 1.2 7.2 22.7 1.4 7.0 15.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Fungal_trans PF04082.13 EPS33900.1 - 1.4e-12 47.0 0.1 2.2e-12 46.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS33900.1 - 7.1e-09 35.4 6.3 1.7e-08 34.2 4.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IncA PF04156.9 EPS33900.1 - 1.4 8.4 5.1 2.5 7.6 3.5 1.3 1 0 0 1 1 1 0 IncA protein DUF2834 PF11196.3 EPS33901.1 - 0.0011 19.0 17.4 0.071 13.2 0.2 3.6 2 1 0 2 2 2 1 Protein of unknown function (DUF2834) DUF4199 PF13858.1 EPS33901.1 - 0.0074 16.2 0.1 0.0074 16.2 0.1 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF4199) zf-DHHC PF01529.15 EPS33901.1 - 8.7 5.6 6.8 32 3.8 0.2 2.8 2 2 0 2 2 2 0 DHHC palmitoyltransferase ACT_3 PF10000.4 EPS33902.1 - 1.1e-16 60.3 0.2 2.2e-16 59.3 0.1 1.6 2 0 0 2 2 2 1 ACT domain ACT_7 PF13840.1 EPS33902.1 - 9.1e-10 37.9 0.0 1.7e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 ACT domain zf-C2H2_4 PF13894.1 EPS33903.1 - 0.53 10.7 2.6 0.51 10.7 0.3 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Zn_clus PF00172.13 EPS33905.1 - 2.4e-10 40.1 8.2 3.8e-10 39.5 5.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Copper-fist PF00649.13 EPS33907.1 - 5.5e-22 76.6 2.8 5.5e-22 76.6 1.9 3.0 2 1 1 3 3 3 1 Copper fist DNA binding domain Aminotran_1_2 PF00155.16 EPS33908.1 - 5.8e-39 134.0 0.0 8.4e-39 133.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II RPN7 PF10602.4 EPS33909.1 - 1.5e-51 174.2 0.2 3e-51 173.2 0.1 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EPS33909.1 - 9.9e-16 57.9 0.0 1.9e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 PCI domain Sugar_tr PF00083.19 EPS33911.1 - 7e-28 97.3 25.4 2.2e-19 69.4 6.7 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EPS33911.1 - 1e-15 57.3 37.2 5.2e-10 38.5 13.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PDR_CDR PF06422.7 EPS33911.1 - 4.7 6.9 5.5 1.5 8.5 0.2 2.7 3 0 0 3 3 3 0 CDR ABC transporter DUF1469 PF07332.6 EPS33911.1 - 7.3 6.3 10.0 0.51 10.0 1.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) PEX11 PF05648.9 EPS33912.1 - 3.9e-74 248.6 0.3 4.4e-74 248.5 0.2 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) PEPCK_ATP PF01293.15 EPS33916.1 - 1.8e-217 722.4 0.0 2.1e-217 722.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_25 PF13481.1 EPS33916.1 - 0.04 13.3 0.1 0.84 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EPS33916.1 - 0.077 12.8 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EPS33916.1 - 0.14 12.4 0.1 16 5.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EPS33916.1 - 0.17 11.8 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Mito_carr PF00153.22 EPS33917.1 - 1.2e-57 191.5 4.2 1.4e-20 72.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MFS_1 PF07690.11 EPS33918.1 - 6.1e-10 38.3 35.0 1.3e-09 37.2 24.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EPS33918.1 - 1.7e-08 34.1 5.8 1.7e-08 34.1 4.0 2.4 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Imm38 PF15599.1 EPS33918.1 - 0.0023 17.4 0.0 0.0041 16.6 0.0 1.3 1 0 0 1 1 1 1 Immunity protein 38 Choline_sulf_C PF12411.3 EPS33918.1 - 0.079 12.8 2.0 0.089 12.6 0.1 2.0 2 0 0 2 2 2 0 Choline sulfatase enzyme C terminal zf-Nse PF11789.3 EPS33919.1 - 2.1e-19 68.7 0.6 3.6e-19 68.0 0.4 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EPS33919.1 - 9.3e-06 25.2 0.3 2.5e-05 23.8 0.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 EPS33919.1 - 0.00025 20.8 0.1 0.0004 20.1 0.0 1.3 1 0 0 1 1 1 1 Ring finger domain U-box PF04564.10 EPS33919.1 - 0.0023 17.8 0.0 0.0057 16.5 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-C3HC4 PF00097.20 EPS33919.1 - 0.0045 16.6 0.1 0.0082 15.7 0.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPS33919.1 - 0.035 14.1 0.3 0.063 13.3 0.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPS33919.1 - 0.092 12.4 0.7 0.22 11.2 0.5 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DNA_ligase_ZBD PF03119.11 EPS33919.1 - 0.098 12.3 0.1 0.31 10.7 0.1 1.9 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain zf-C3HC4_4 PF15227.1 EPS33919.1 - 0.11 12.4 0.1 0.31 10.9 0.1 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-ribbon_3 PF13248.1 EPS33919.1 - 0.13 11.5 0.1 0.29 10.4 0.0 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zf-MIZ PF02891.15 EPS33919.1 - 0.38 10.3 2.3 1.5 8.4 1.6 1.9 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger Pox_MCEL PF03291.11 EPS33920.1 - 9.9e-62 208.7 0.0 1.1e-31 109.9 0.0 3.8 3 1 0 3 3 3 3 mRNA capping enzyme Methyltransf_12 PF08242.7 EPS33920.1 - 1.2e-07 32.1 0.0 0.0019 18.6 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 EPS33920.1 - 3e-07 30.8 0.0 0.014 15.8 0.0 2.8 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.1 EPS33920.1 - 1.4e-06 28.0 0.0 2.5e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPS33920.1 - 4.1e-06 26.4 0.0 0.0015 18.1 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EPS33920.1 - 7.8e-06 26.4 0.0 1.7e-05 25.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPS33920.1 - 0.0017 18.6 0.0 0.0081 16.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EPS33920.1 - 0.0094 14.9 0.0 0.016 14.2 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_9 PF08003.6 EPS33920.1 - 0.056 12.1 0.0 0.1 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) zf-C3HC PF07967.8 EPS33922.1 - 6.3e-44 148.9 0.3 1.3e-38 131.7 0.1 2.3 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.5 EPS33922.1 - 1.3e-32 111.4 1.7 4.5e-30 103.3 0.0 2.9 3 0 0 3 3 3 2 Rsm1-like BIR PF00653.16 EPS33922.1 - 0.006 16.9 1.6 2.2 8.7 0.0 2.8 3 0 0 3 3 3 2 Inhibitor of Apoptosis domain COX15-CtaA PF02628.10 EPS33923.1 - 1.1e-97 326.6 6.5 1.3e-97 326.3 4.5 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein PQ-loop PF04193.9 EPS33923.1 - 0.11 12.0 1.1 6.7 6.3 0.1 2.8 2 0 0 2 2 2 0 PQ loop repeat Phage-tail_3 PF13550.1 EPS33924.1 - 0.0079 15.9 0.6 0.017 14.9 0.4 1.5 1 0 0 1 1 1 1 Putative phage tail protein tRNA-synt_2 PF00152.15 EPS33925.1 - 3.4e-92 308.7 0.5 5.6e-92 308.0 0.3 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EPS33925.1 - 2.1e-13 49.9 0.0 5.7e-13 48.5 0.0 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EPS33925.1 - 3.9e-06 26.2 0.1 0.0079 15.4 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EPS33925.1 - 0.029 13.9 0.1 0.79 9.2 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) Dynamin_M PF01031.15 EPS33926.1 - 5.2e-28 97.6 0.1 3.6e-21 75.2 0.0 2.2 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.18 EPS33926.1 - 4.6e-25 88.3 0.0 2.8e-24 85.8 0.0 2.2 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EPS33926.1 - 0.0001 22.2 0.1 0.0099 15.8 0.0 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase GED PF02212.13 EPS33926.1 - 0.00012 21.9 0.2 0.00041 20.1 0.0 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain Miro PF08477.8 EPS33926.1 - 0.0052 17.2 0.1 0.025 15.0 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein IIGP PF05049.8 EPS33926.1 - 0.036 12.8 0.1 5.1 5.7 0.0 2.5 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_16 PF13191.1 EPS33926.1 - 0.066 13.1 0.3 3.8 7.4 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain NTP_transferase PF00483.18 EPS33927.1 - 1.4e-29 103.1 0.0 2e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 EPS33927.1 - 1.6e-10 39.9 5.7 3.3e-06 26.3 0.2 3.7 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EPS33927.1 - 4.5e-08 33.3 0.0 7.1e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain IspD PF01128.14 EPS33927.1 - 0.0096 15.4 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Glyco_tranf_2_3 PF13641.1 EPS33927.1 - 0.013 15.3 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase like family 2 DUF2968 PF11180.3 EPS33927.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Hexapep_2 PF14602.1 EPS33927.1 - 0.36 10.4 2.2 1.5 8.4 0.1 2.8 2 0 0 2 2 2 0 Hexapeptide repeat of succinyl-transferase MARVEL PF01284.18 EPS33928.1 - 0.047 13.5 17.0 0.058 13.2 11.8 1.1 1 0 0 1 1 1 0 Membrane-associating domain TMEM192 PF14802.1 EPS33928.1 - 0.14 10.9 3.2 0.098 11.4 1.2 1.4 1 1 0 1 1 1 0 TMEM192 family Dynamin_N PF00350.18 EPS33929.1 - 3.5e-16 59.4 0.0 3.8e-15 56.1 0.0 2.8 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 EPS33929.1 - 1.9e-06 27.7 0.0 0.0022 17.9 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase DUF258 PF03193.11 EPS33929.1 - 8.3e-05 21.8 0.2 0.0049 16.0 0.1 3.5 3 1 0 3 3 3 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EPS33929.1 - 0.0001 22.5 0.0 0.001 19.3 0.0 2.7 2 0 0 2 2 2 1 ABC transporter AIG1 PF04548.11 EPS33929.1 - 0.00061 18.9 1.9 0.0016 17.5 0.0 2.7 3 0 0 3 3 3 1 AIG1 family AAA_22 PF13401.1 EPS33929.1 - 0.01 16.0 0.5 0.57 10.3 0.0 3.5 2 1 1 3 3 3 1 AAA domain IIGP PF05049.8 EPS33929.1 - 0.011 14.6 0.0 0.088 11.6 0.0 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) DUF2408 PF10303.4 EPS33929.1 - 0.015 15.4 1.4 1 9.4 0.1 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2408) AAA_29 PF13555.1 EPS33929.1 - 0.063 12.8 2.3 0.2 11.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_17 PF13207.1 EPS33929.1 - 0.98 10.2 5.9 1.3 9.8 0.0 3.3 2 1 0 2 2 2 0 AAA domain ResIII PF04851.10 EPS33929.1 - 5 6.9 7.7 4.3 7.1 0.1 3.6 5 0 0 5 5 5 0 Type III restriction enzyme, res subunit Abhydrolase_5 PF12695.2 EPS33930.1 - 2.7e-17 62.8 0.1 4.1e-17 62.2 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPS33930.1 - 1.9e-08 34.4 5.8 3.1e-08 33.7 4.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.8 EPS33930.1 - 3.3e-07 28.9 0.0 0.01 14.1 0.0 2.1 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.2 EPS33930.1 - 6e-07 28.6 0.0 1.1e-06 27.7 0.0 1.4 1 1 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EPS33930.1 - 6.3e-07 28.4 0.1 1.2e-06 27.5 0.0 1.4 1 1 0 1 1 1 1 Chlorophyllase Peptidase_S9 PF00326.16 EPS33930.1 - 0.0035 16.5 0.0 0.0075 15.5 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family zf-RING_2 PF13639.1 EPS33931.1 - 6.9e-09 35.3 2.6 1.1e-08 34.7 1.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EPS33931.1 - 8.4e-06 25.8 0.3 1.6e-05 24.9 0.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EPS33931.1 - 0.00061 19.5 0.4 0.00095 18.9 0.3 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EPS33931.1 - 0.0053 16.7 1.8 0.0095 15.9 1.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_3 PF14369.1 EPS33931.1 - 0.053 13.5 0.2 0.14 12.2 0.2 1.7 1 0 0 1 1 1 0 zinc-finger zf-C3HC4 PF00097.20 EPS33931.1 - 0.13 11.9 0.6 0.26 10.9 0.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EPS33931.1 - 0.18 11.5 1.9 2.1 8.1 1.5 2.1 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-DHHC PF01529.15 EPS33932.1 - 3.8e-31 107.8 6.2 8.1e-31 106.7 4.3 1.6 1 0 0 1 1 1 1 DHHC palmitoyltransferase Atx10homo_assoc PF09759.4 EPS33932.1 - 2.2e-30 104.4 0.3 7.8e-30 102.6 0.0 2.0 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain RYDR_ITPR PF01365.16 EPS33932.1 - 0.16 11.1 0.9 0.39 9.9 0.1 1.9 2 0 0 2 2 2 0 RIH domain Rap1_C PF11626.3 EPS33933.1 - 8.3e-22 76.8 0.1 1.7e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.6 EPS33933.1 - 5.5e-16 58.1 0.1 1.3e-15 56.9 0.1 1.7 1 0 0 1 1 1 1 Rap1 Myb domain Rap1-DNA-bind PF09197.5 EPS33933.1 - 0.00018 21.9 0.0 0.00042 20.8 0.0 1.6 1 0 0 1 1 1 1 Rap1, DNA-binding Chromo PF00385.19 EPS33934.1 - 6e-12 45.0 1.6 1.3e-11 43.9 0.9 1.8 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 EPS33934.1 - 2.1e-08 33.9 0.2 1.4e-07 31.1 0.0 2.2 2 0 0 2 2 2 1 Chromo shadow domain FAM176 PF14851.1 EPS33934.1 - 2.1 7.9 5.7 9.4 5.8 0.7 2.2 2 0 0 2 2 2 0 FAM176 family Cpn60_TCP1 PF00118.19 EPS33935.1 - 9.8e-145 482.8 3.7 1.1e-144 482.6 2.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family NotI PF12183.3 EPS33935.1 - 0.15 11.1 0.8 1.6 7.7 0.1 2.2 2 0 0 2 2 2 0 Restriction endonuclease NotI Enolase_N PF03952.11 EPS33935.1 - 0.28 11.1 2.9 28 4.6 0.0 3.4 3 0 0 3 3 3 0 Enolase, N-terminal domain He_PIG_assoc PF10632.4 EPS33936.1 - 0.073 12.4 0.2 0.15 11.3 0.1 1.5 1 0 0 1 1 1 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase DUF3295 PF11702.3 EPS33938.1 - 7.8e-182 605.7 28.4 9e-182 605.5 19.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 EPS33938.1 - 2e-12 46.4 1.6 4.1e-12 45.4 1.1 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Con-6 PF10346.4 EPS33938.1 - 0.2 11.1 1.6 0.5 9.8 1.1 1.7 1 0 0 1 1 1 0 Conidiation protein 6 zf-CHY PF05495.7 EPS33941.1 - 2.5e-19 69.2 28.2 5.8e-19 68.0 9.3 3.3 3 0 0 3 3 3 2 CHY zinc finger CENP-B_dimeris PF09026.5 EPS33941.1 - 5.2 7.3 11.7 0.11 12.7 3.2 1.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Glyoxalase PF00903.20 EPS33942.1 - 4.4e-22 78.4 1.1 1e-15 57.8 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EPS33942.1 - 2e-14 53.5 0.5 3.1e-06 27.1 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EPS33942.1 - 7.8e-10 39.3 0.0 0.00039 20.9 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.1 EPS33942.1 - 6.8e-09 35.8 0.3 0.00014 21.8 0.2 2.9 3 0 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 EPS33942.1 - 1.3e-07 31.6 0.5 3.9e-06 26.8 0.1 2.6 2 1 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal TPR_11 PF13414.1 EPS33943.1 - 0.0066 16.0 0.0 0.12 11.9 0.0 2.3 2 0 0 2 2 2 1 TPR repeat TPR_17 PF13431.1 EPS33943.1 - 0.013 15.6 0.1 0.096 12.9 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EPS33943.1 - 0.11 12.4 0.7 0.59 10.1 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat HgmA PF04209.8 EPS33944.1 - 7.9e-191 634.0 0.2 9e-191 633.8 0.1 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase FAA_hydrolase PF01557.13 EPS33945.1 - 1.1e-47 162.3 0.0 1.4e-47 161.9 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 EPS33945.1 - 5.2e-24 84.3 0.0 2.3e-23 82.1 0.1 1.9 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal GST_N_3 PF13417.1 EPS33946.1 - 6.2e-12 45.5 0.1 1e-11 44.8 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EPS33946.1 - 1.4e-09 37.8 0.0 2.8e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EPS33946.1 - 7.1e-08 32.5 0.0 1.1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EPS33946.1 - 1.1e-06 28.4 0.0 2.1e-06 27.6 0.0 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EPS33946.1 - 0.00034 20.4 0.0 0.00083 19.2 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EPS33946.1 - 0.024 15.1 0.0 0.046 14.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Zn_clus PF00172.13 EPS33947.1 - 6.8e-07 29.0 5.9 1.2e-06 28.3 4.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EPS33947.1 - 0.1 11.4 3.8 0.51 9.1 0.1 2.3 2 0 0 2 2 2 0 Fungal specific transcription factor domain Tim17 PF02466.14 EPS33948.1 - 1.1e-34 119.2 7.3 1.3e-34 118.9 5.1 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HATPase_c_4 PF13749.1 EPS33948.1 - 0.0063 16.2 0.0 0.011 15.5 0.0 1.5 1 1 0 1 1 1 1 ATP-dependent DNA helicase recG C-terminal TadE PF07811.7 EPS33948.1 - 0.17 11.7 1.4 0.27 11.1 0.1 2.0 2 0 0 2 2 2 0 TadE-like protein PsaL PF02605.10 EPS33948.1 - 0.89 9.0 3.9 13 5.2 0.0 2.3 2 0 0 2 2 2 0 Photosystem I reaction centre subunit XI Asparaginase_2 PF01112.13 EPS33949.1 - 3.1e-42 144.4 0.0 4.7e-18 64.9 0.0 3.2 3 0 0 3 3 3 3 Asparaginase ABC2_membrane PF01061.19 EPS33953.1 - 5.5e-89 296.8 56.9 2.3e-48 164.1 15.9 3.3 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 EPS33953.1 - 4.8e-41 138.6 1.4 3.5e-30 103.7 0.0 2.7 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 EPS33953.1 - 2.1e-38 131.6 0.0 2e-19 70.2 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 EPS33953.1 - 5.5e-09 35.5 50.4 2.6e-06 26.7 13.3 3.2 2 1 1 3 3 3 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 EPS33953.1 - 1.3e-08 34.8 0.0 1.2e-07 31.6 0.0 2.6 2 0 0 2 2 2 1 ABC-transporter extracellular N-terminal AAA_16 PF13191.1 EPS33953.1 - 7.5e-07 29.3 0.9 2.1e-05 24.5 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.1 EPS33953.1 - 1.3e-06 28.6 0.2 0.00067 19.7 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPS33953.1 - 3.5e-06 27.8 0.0 0.0051 17.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EPS33953.1 - 8.2e-05 22.1 0.1 0.00091 18.7 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 EPS33953.1 - 0.00011 21.4 0.0 0.00035 19.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EPS33953.1 - 0.00014 21.9 0.2 0.13 12.4 0.1 3.3 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EPS33953.1 - 0.00026 20.4 1.4 0.014 14.7 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.1 EPS33953.1 - 0.00053 19.4 0.5 0.069 12.6 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.1 EPS33953.1 - 0.0024 17.7 0.0 0.2 11.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EPS33953.1 - 0.0034 17.0 0.4 0.41 10.4 0.1 2.5 2 0 0 2 2 2 1 Part of AAA domain FtsK_SpoIIIE PF01580.13 EPS33953.1 - 0.0035 16.8 0.2 2.7 7.3 0.0 2.6 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_18 PF13238.1 EPS33953.1 - 0.0059 16.9 0.1 0.13 12.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EPS33953.1 - 0.013 15.4 0.1 0.037 13.9 0.1 1.8 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EPS33953.1 - 0.015 14.9 0.5 0.16 11.5 0.2 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 EPS33953.1 - 0.025 14.2 0.5 0.32 10.6 0.1 2.4 2 0 0 2 2 2 0 NACHT domain AAA_10 PF12846.2 EPS33953.1 - 0.065 12.6 1.7 4.4 6.6 0.1 2.5 2 1 0 2 2 2 0 AAA-like domain MMR_HSR1 PF01926.18 EPS33953.1 - 0.16 11.9 0.1 2.9 7.8 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase CPSF73-100_C PF11718.3 EPS33953.1 - 0.19 11.0 0.3 0.38 10.0 0.2 1.4 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term T2SE PF00437.15 EPS33953.1 - 0.3 9.9 0.6 3.9 6.2 0.1 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein Potyvirid-P3 PF13608.1 EPS33954.1 - 0.049 12.7 0.3 0.071 12.2 0.2 1.1 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein zf-C2HC_2 PF13913.1 EPS33954.1 - 0.15 11.7 1.0 0.28 10.9 0.1 1.9 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Amidase PF01425.16 EPS33955.1 - 4.9e-94 315.6 0.0 6e-94 315.3 0.0 1.1 1 0 0 1 1 1 1 Amidase 2OG-FeII_Oxy_2 PF13532.1 EPS33956.1 - 1.8e-31 109.5 0.0 5.7e-31 107.8 0.0 1.7 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EPS33956.1 - 0.0065 16.9 0.0 0.016 15.7 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.20 EPS33957.1 - 5.3e-72 242.0 0.0 6.5e-72 241.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS33957.1 - 4.6e-31 107.8 0.0 6e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPS33957.1 - 0.00029 19.8 0.0 0.00051 19.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EPS33957.1 - 0.0072 15.1 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 EPS33957.1 - 0.0091 15.7 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EPS33957.1 - 0.11 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Peptidase_C2 PF00648.16 EPS33958.1 - 2.2e-56 191.0 1.4 5.6e-36 124.0 0.2 2.3 2 0 0 2 2 2 2 Calpain family cysteine protease Abhydrolase_3 PF07859.8 EPS33959.1 - 6.3e-07 29.1 0.4 6.3e-05 22.6 0.3 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EPS33959.1 - 0.0015 18.0 0.1 0.0027 17.1 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 EPS33959.1 - 0.0044 16.2 0.0 0.0075 15.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 EPS33959.1 - 0.01 15.3 0.0 0.028 13.8 0.0 1.6 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.2 EPS33959.1 - 0.048 13.4 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family BAAT_C PF08840.6 EPS33959.1 - 0.16 11.6 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Fungal_trans PF04082.13 EPS33960.1 - 1.8e-22 79.4 0.0 3.8e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS33960.1 - 1.2e-08 34.7 13.1 2e-08 34.0 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyoxalase PF00903.20 EPS33961.1 - 1.9e-36 124.8 0.1 4.6e-19 68.6 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EPS33961.1 - 2.3e-29 102.1 0.1 1.5e-13 51.3 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EPS33961.1 - 2e-19 69.5 0.2 1.2e-07 31.7 0.0 3.9 1 1 2 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EPS33961.1 - 8.6e-07 29.0 0.0 0.023 14.6 0.0 2.9 1 1 1 2 2 2 2 Glyoxalase-like domain Mnd1 PF03962.10 EPS33964.1 - 0.034 13.8 3.6 0.89 9.1 0.2 2.3 2 0 0 2 2 2 0 Mnd1 family DUF3275 PF11679.3 EPS33964.1 - 3.3 7.2 9.4 3.9 7.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) Arrestin_C PF02752.17 EPS33965.1 - 1.9e-18 66.8 0.1 3.7e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EPS33965.1 - 1.3e-14 54.2 0.0 2.7e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 EPS33965.1 - 0.0018 17.7 0.0 0.004 16.6 0.0 1.6 1 1 0 1 1 1 1 Arrestin_N terminal like CAP59_mtransfer PF11735.3 EPS33966.1 - 1.1e-43 149.1 0.0 1.6e-43 148.6 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 PRC PF05239.11 EPS33966.1 - 0.025 14.4 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 PRC-barrel domain Rootletin PF15035.1 EPS33967.1 - 0.011 15.6 0.1 0.012 15.5 0.0 1.1 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion SNARE PF05739.14 EPS33967.1 - 0.017 14.8 0.0 0.028 14.1 0.0 1.4 1 1 0 1 1 1 0 SNARE domain DUF2207 PF09972.4 EPS33967.1 - 0.09 11.3 0.0 0.095 11.2 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Peptidase_M9_N PF08453.5 EPS33967.1 - 0.12 11.6 0.1 0.13 11.5 0.1 1.1 1 0 0 1 1 1 0 Peptidase family M9 N-terminal FAM176 PF14851.1 EPS33967.1 - 2.4 7.8 4.9 3.8 7.1 0.8 2.0 1 1 1 2 2 2 0 FAM176 family DAO PF01266.19 EPS33968.1 - 2.9e-55 187.6 0.0 3.4e-55 187.3 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPS33968.1 - 2.1e-07 30.8 0.0 5.8e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EPS33968.1 - 6.3e-06 25.2 0.0 0.039 12.7 0.0 2.5 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.9 EPS33968.1 - 7.1e-06 26.0 0.0 0.0068 16.3 0.0 2.5 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EPS33968.1 - 2.1e-05 23.5 0.3 0.0043 15.9 0.0 2.3 2 1 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EPS33968.1 - 6.2e-05 23.1 0.0 0.004 17.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EPS33968.1 - 0.00054 19.1 0.0 0.00081 18.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 EPS33968.1 - 0.0012 18.6 0.1 0.4 10.4 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EPS33968.1 - 0.0093 16.3 0.0 0.019 15.3 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EPS33968.1 - 0.017 13.5 0.0 3.4 6.0 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein TrkA_N PF02254.13 EPS33968.1 - 0.018 15.0 0.0 0.039 13.9 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Thi4 PF01946.12 EPS33968.1 - 0.03 13.4 0.0 0.36 9.8 0.0 2.0 2 0 0 2 2 2 0 Thi4 family Shikimate_DH PF01488.15 EPS33968.1 - 0.13 12.3 0.0 0.35 10.9 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF2235 PF09994.4 EPS33970.1 - 1.5e-67 227.9 0.2 2.4e-67 227.2 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DNA_primase_lrg PF04104.9 EPS33970.1 - 0.084 12.1 0.8 0.13 11.4 0.0 1.6 2 0 0 2 2 2 0 Eukaryotic and archaeal DNA primase, large subunit UPF0560 PF10577.4 EPS33971.1 - 1.9 6.6 4.2 2.6 6.1 2.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 RTA1 PF04479.8 EPS33974.1 - 4.8e-20 72.0 2.6 7.1e-20 71.4 1.8 1.2 1 0 0 1 1 1 1 RTA1 like protein MpPF26 PF07666.6 EPS33974.1 - 0.29 11.0 2.6 0.32 10.9 0.1 2.1 2 0 0 2 2 2 0 M penetrans paralogue family 26 Zn_clus PF00172.13 EPS33975.1 - 2.3e-07 30.5 15.3 3.8e-07 29.9 10.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zds_C PF08632.5 EPS33976.1 - 4.5e-30 102.7 0.8 9e-30 101.8 0.6 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Suf PF05843.9 EPS33976.1 - 2 8.0 16.6 0.44 10.2 4.9 2.7 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF500 PF04366.7 EPS33977.1 - 7.1e-44 148.2 0.5 1.5e-43 147.2 0.4 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 EPS33977.1 - 1.9e-14 52.7 0.5 4.6e-14 51.5 0.1 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EPS33977.1 - 3e-11 42.7 0.1 5.3e-11 41.9 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EPS33977.1 - 4.5e-10 38.8 0.0 1.1e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF1373 PF07117.6 EPS33977.1 - 0.021 14.5 1.3 0.042 13.5 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1373) FXR1P_C PF12235.3 EPS33977.1 - 0.08 13.0 7.3 0.13 12.3 5.1 1.4 1 0 0 1 1 1 0 Fragile X-related 1 protein C terminal Miro PF08477.8 EPS33978.1 - 1.4e-37 128.8 0.0 5.1e-19 68.9 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 EPS33978.1 - 3.3e-35 119.6 0.0 6e-35 118.8 0.0 1.4 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.7 EPS33978.1 - 7.7e-32 108.4 0.1 1.3e-31 107.6 0.0 1.4 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 EPS33978.1 - 1.9e-23 82.6 0.0 2.1e-14 53.2 0.0 2.1 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 EPS33978.1 - 1e-10 41.5 0.0 0.00059 19.7 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_1 PF00036.27 EPS33978.1 - 8.7e-06 24.6 0.9 0.047 13.0 0.1 2.6 2 0 0 2 2 2 2 EF hand AAA_16 PF13191.1 EPS33978.1 - 1.4e-05 25.2 1.8 0.051 13.5 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EPS33978.1 - 2e-05 23.9 0.3 0.014 14.9 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain EF-hand_6 PF13405.1 EPS33978.1 - 2.9e-05 23.5 1.2 0.049 13.5 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain AAA_28 PF13521.1 EPS33978.1 - 7.3e-05 22.7 0.1 0.03 14.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain EF-hand_7 PF13499.1 EPS33978.1 - 7.6e-05 22.7 0.2 0.14 12.2 0.1 2.9 3 0 0 3 3 2 1 EF-hand domain pair Dynamin_N PF00350.18 EPS33978.1 - 8.4e-05 22.4 0.5 0.4 10.4 0.1 3.1 2 1 1 3 3 3 2 Dynamin family AAA_22 PF13401.1 EPS33978.1 - 9.9e-05 22.4 0.3 0.98 9.5 0.0 2.9 2 1 1 3 3 3 2 AAA domain GTP_EFTU PF00009.22 EPS33978.1 - 0.00011 21.7 0.6 0.44 9.9 0.0 3.2 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain EF-hand_8 PF13833.1 EPS33978.1 - 0.00064 19.2 0.2 0.059 12.9 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair FtsK_SpoIIIE PF01580.13 EPS33978.1 - 0.0011 18.4 0.1 0.43 10.0 0.0 2.8 3 0 0 3 3 3 1 FtsK/SpoIIIE family MobB PF03205.9 EPS33978.1 - 0.0013 18.4 0.2 0.23 11.1 0.2 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.13 EPS33978.1 - 0.0021 17.6 0.3 0.039 13.4 0.0 2.5 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 EPS33978.1 - 0.0025 17.3 0.0 0.73 9.2 0.0 2.9 2 1 1 3 3 3 1 AAA-like domain AAA_18 PF13238.1 EPS33978.1 - 0.0026 18.0 0.0 3.5 7.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EPS33978.1 - 0.0027 17.1 0.0 2.5 7.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EPS33978.1 - 0.0037 17.4 0.0 0.87 9.7 0.0 2.5 2 0 0 2 2 2 1 RNA helicase NACHT PF05729.7 EPS33978.1 - 0.0049 16.5 0.1 3.8 7.1 0.0 2.6 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.1 EPS33978.1 - 0.0052 16.6 0.0 1.6 8.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EPS33978.1 - 0.0069 16.6 0.0 4.7 7.5 0.0 2.5 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.1 EPS33978.1 - 0.0071 15.9 0.1 0.13 11.8 0.1 2.2 2 0 0 2 2 2 1 AAA domain Arf PF00025.16 EPS33978.1 - 0.0097 15.1 0.1 8.3 5.6 0.0 3.1 3 0 0 3 3 3 0 ADP-ribosylation factor family AAA_17 PF13207.1 EPS33978.1 - 0.014 16.2 0.0 7.2 7.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EPS33978.1 - 0.02 14.0 0.1 1.7 7.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 cobW PF02492.14 EPS33978.1 - 0.044 13.2 2.0 1.3 8.4 0.1 3.7 4 1 0 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain DUF815 PF05673.8 EPS33978.1 - 0.053 12.4 0.4 1.8 7.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Septin PF00735.13 EPS33978.1 - 0.054 12.5 0.0 0.77 8.7 0.0 2.1 2 0 0 2 2 2 0 Septin SMC_N PF02463.14 EPS33978.1 - 0.06 12.5 0.3 1.9 7.6 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain EF-hand_5 PF13202.1 EPS33978.1 - 0.072 12.4 3.5 3.9 6.9 0.2 2.6 2 0 0 2 2 2 0 EF hand AAA PF00004.24 EPS33978.1 - 0.085 13.0 0.5 12 6.1 0.0 3.1 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) IIGP PF05049.8 EPS33978.1 - 0.086 11.6 0.5 1.4 7.6 0.1 2.2 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) TrwB_AAD_bind PF10412.4 EPS33978.1 - 0.091 11.3 0.1 11 4.5 0.0 2.7 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain AAA_5 PF07728.9 EPS33978.1 - 0.098 12.3 0.2 22 4.7 0.1 2.8 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) ATP_bind_1 PF03029.12 EPS33978.1 - 0.13 11.8 1.3 29 4.0 0.0 3.4 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.1 EPS33978.1 - 0.19 12.0 0.1 32 4.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 EPS33978.1 - 0.21 10.3 0.3 4.5 5.9 0.0 2.4 2 0 0 2 2 2 0 ArgK protein WD40 PF00400.27 EPS33979.1 - 2.8e-17 61.8 12.1 1.8e-06 27.6 0.4 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat IKI3 PF04762.7 EPS33979.1 - 0.00023 19.1 0.0 0.011 13.6 0.0 2.0 1 1 1 2 2 2 2 IKI3 family Cytochrom_D1 PF02239.11 EPS33979.1 - 0.0018 16.6 0.0 0.0039 15.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain eIF2A PF08662.6 EPS33979.1 - 0.009 15.7 0.0 1.2 8.7 0.0 2.2 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Pkinase PF00069.20 EPS33981.1 - 1e-27 96.9 0.0 1.3e-27 96.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS33981.1 - 2.7e-07 29.9 0.0 2.5e-05 23.4 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EPS33981.1 - 0.11 12.2 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family AAA_10 PF12846.2 EPS33982.1 - 4.2e-09 36.2 0.1 6.5e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 AAA-like domain Zot PF05707.7 EPS33982.1 - 0.0003 20.2 0.1 0.0041 16.6 0.0 2.3 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) FtsK_SpoIIIE PF01580.13 EPS33982.1 - 0.0013 18.2 0.2 0.012 15.0 0.0 2.1 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.1 EPS33982.1 - 0.0014 18.7 0.1 2.7 8.1 0.0 2.7 3 0 0 3 3 3 2 AAA domain Adeno_IVa2 PF02456.10 EPS33982.1 - 0.0031 16.2 0.0 0.0058 15.3 0.0 1.4 1 0 0 1 1 1 1 Adenovirus IVa2 protein DEAD PF00270.24 EPS33982.1 - 0.043 13.3 0.0 1.5 8.3 0.0 2.7 3 0 0 3 3 3 0 DEAD/DEAH box helicase Zeta_toxin PF06414.7 EPS33982.1 - 0.097 11.7 0.0 0.28 10.2 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin GPI-anchored PF10342.4 EPS33983.1 - 8e-18 64.7 1.9 1.2e-17 64.1 1.3 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CUE PF02845.11 EPS33984.1 - 2.7e-12 45.9 0.3 1.6e-08 33.8 0.0 3.3 3 0 0 3 3 3 2 CUE domain Smr PF01713.16 EPS33984.1 - 1.1e-09 38.3 0.5 2.4e-09 37.2 0.3 1.6 1 0 0 1 1 1 1 Smr domain SelR PF01641.13 EPS33985.1 - 4.4e-50 168.5 0.0 5.8e-50 168.1 0.0 1.1 1 0 0 1 1 1 1 SelR domain TF_Zn_Ribbon PF08271.7 EPS33985.1 - 0.083 12.2 0.9 0.36 10.1 0.1 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding DZR PF12773.2 EPS33985.1 - 0.19 11.5 3.0 4.7 7.1 2.1 2.3 1 1 1 2 2 2 0 Double zinc ribbon ArfGap PF01412.13 EPS33986.1 - 4.9e-40 135.9 1.4 7.3e-40 135.4 1.0 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Sigma_reg_N PF13800.1 EPS33989.1 - 0.02 14.9 0.4 0.022 14.7 0.2 1.2 1 0 0 1 1 1 0 Sigma factor regulator N-terminal CbiN PF02553.10 EPS33989.1 - 0.049 13.6 0.2 0.057 13.4 0.1 1.2 1 0 0 1 1 1 0 Cobalt transport protein component CbiN Tad PF13400.1 EPS33989.1 - 0.052 13.5 2.3 0.062 13.3 1.6 1.1 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like Tetraspannin PF00335.15 EPS33989.1 - 0.14 11.4 0.2 0.14 11.4 0.1 1.0 1 0 0 1 1 1 0 Tetraspanin family EpuA PF11772.3 EPS33989.1 - 2.5 7.6 8.4 3.5 7.1 5.8 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta Med13_C PF06333.7 EPS33990.1 - 7.6e-103 344.2 0.1 1.5e-102 343.2 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit 13 C-terminal Med13_N PF11597.3 EPS33990.1 - 2.3e-62 210.9 0.0 5.1e-62 209.8 0.0 1.6 2 0 0 2 2 2 1 Mediator complex subunit 13 N-terminal Rsm1 PF08600.5 EPS33990.1 - 0.094 12.5 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 Rsm1-like NUC153 PF08159.7 EPS33991.1 - 3.9e-11 42.3 3.6 1e-10 40.9 2.5 1.7 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 EPS33991.1 - 0.0013 18.5 0.0 1.3 9.0 0.0 3.8 3 0 0 3 3 3 1 WD domain, G-beta repeat ATG13 PF10033.4 EPS33992.1 - 8.1e-72 241.4 0.0 1.3e-71 240.7 0.0 1.4 1 0 0 1 1 1 1 Autophagy-related protein 13 p450 PF00067.17 EPS33994.1 - 3.8e-29 101.5 0.0 4.9e-29 101.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 LIP PF03583.9 EPS33995.1 - 2.1e-65 220.8 0.2 3e-65 220.3 0.1 1.1 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.16 EPS33995.1 - 0.00063 19.0 0.1 0.011 15.0 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EPS33995.1 - 0.00069 19.3 0.1 0.0015 18.2 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPS33995.1 - 0.0014 18.5 0.0 0.0024 17.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EPS33995.1 - 0.0014 18.0 0.0 0.0032 16.9 0.0 1.5 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.13 EPS33995.1 - 0.01 15.1 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family RCC1 PF00415.13 EPS33996.1 - 1.3e-20 73.3 0.3 1.9e-06 27.9 0.0 5.3 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 EPS33996.1 - 2.4e-12 46.8 0.1 1.5e-07 31.4 0.0 2.8 2 0 0 2 2 2 2 BTB/POZ domain RCC1_2 PF13540.1 EPS33996.1 - 3.5e-11 42.4 3.7 2.3e-07 30.2 0.0 3.3 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.1 EPS33996.1 - 4e-07 30.3 0.4 0.00076 19.9 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EPS33996.1 - 0.01 16.1 0.1 0.29 11.4 0.1 2.5 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EPS33996.1 - 0.012 15.7 0.4 2.8 8.4 0.1 3.0 2 0 0 2 2 2 0 Ankyrin repeat Ank_5 PF13857.1 EPS33996.1 - 0.098 12.9 0.3 1.9 8.8 0.1 2.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) TCO89 PF10452.4 EPS33997.1 - 0.00017 20.6 0.5 0.0021 17.0 0.1 3.8 3 1 0 3 3 3 2 TORC1 subunit TCO89 VHS PF00790.14 EPS33998.1 - 1.6e-40 138.0 0.8 2.8e-39 133.9 0.0 2.3 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 EPS33998.1 - 1.6e-16 59.9 1.5 2.7e-16 59.2 1.0 1.3 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 EPS33998.1 - 8.1e-05 21.8 13.5 0.0011 18.2 1.4 3.2 3 0 0 3 3 3 2 Ubiquitin interaction motif FYVE_2 PF02318.11 EPS33998.1 - 0.017 15.0 0.2 0.04 13.8 0.1 1.5 1 0 0 1 1 1 0 FYVE-type zinc finger zf-DHHC PF01529.15 EPS33998.1 - 0.025 14.0 0.4 0.044 13.1 0.3 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase C1_1 PF00130.17 EPS33998.1 - 0.028 14.1 2.8 0.055 13.2 1.9 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) UCH PF00443.24 EPS33999.1 - 3.6e-58 196.7 0.0 6.5e-58 195.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPS33999.1 - 4.9e-28 98.4 0.0 9.9e-28 97.4 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP8_dimer PF08969.6 EPS33999.1 - 0.00041 20.2 0.1 0.0013 18.7 0.0 1.9 2 0 0 2 2 2 1 USP8 dimerisation domain Rhodanese PF00581.15 EPS33999.1 - 0.093 13.0 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 Rhodanese-like domain Cyt-b5 PF00173.23 EPS34000.1 - 2.8e-23 81.5 0.0 3.4e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BTB PF00651.26 EPS34001.1 - 3.9e-07 30.0 0.0 6.7e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EPS34002.1 - 1.8e-11 43.9 0.0 3.3e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain dCMP_cyt_deam_1 PF00383.17 EPS34003.1 - 1.6e-08 34.1 0.0 2e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EPS34003.1 - 0.03 14.1 0.2 3.3 7.5 0.2 2.2 1 1 1 2 2 2 0 Bd3614-like deaminase Pyr_redox_2 PF07992.9 EPS34004.1 - 5e-06 26.5 0.8 3.7e-05 23.7 0.5 2.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPS34004.1 - 7.8e-06 26.0 0.0 0.0011 19.0 0.0 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPS34004.1 - 0.00038 20.2 0.0 0.037 13.8 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 EPS34004.1 - 0.0092 14.9 0.1 0.019 13.9 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Malic_M PF03949.10 EPS34004.1 - 0.12 11.8 0.1 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain Lactamase_B PF00753.22 EPS34006.1 - 2.6e-18 66.3 0.9 3.6e-18 65.9 0.6 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EPS34006.1 - 0.0036 16.8 0.1 0.005 16.4 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF202 PF02656.10 EPS34007.1 - 6.4e-14 51.9 5.4 6.4e-14 51.9 3.7 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF202) KH_1 PF00013.24 EPS34008.1 - 7.9e-87 284.8 19.6 5.7e-12 45.0 0.1 13.1 15 0 0 15 15 15 9 KH domain KH_3 PF13014.1 EPS34008.1 - 1.1e-62 206.8 22.0 2.4e-09 36.6 0.9 12.8 13 0 0 13 13 13 10 KH domain KH_2 PF07650.12 EPS34008.1 - 2.6e-13 49.3 20.7 0.0033 16.9 0.2 7.3 6 1 0 7 7 7 5 KH domain SLS PF14611.1 EPS34008.1 - 1.2e-12 47.7 1.6 0.076 12.4 0.0 7.5 6 4 1 7 7 7 4 Mitochondrial inner-membrane-bound regulator KH_5 PF13184.1 EPS34008.1 - 0.00033 20.4 5.0 25 4.7 0.1 6.4 6 0 0 6 6 6 0 NusA-like KH domain KH_4 PF13083.1 EPS34008.1 - 0.0033 17.0 3.9 11 5.7 0.0 5.1 5 0 0 5 5 5 1 KH domain Transp_cyt_pur PF02133.10 EPS34009.1 - 1.7e-27 96.1 30.1 2.5e-27 95.5 20.9 1.2 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin SAMP PF05924.6 EPS34009.1 - 0.08 12.1 1.1 0.18 10.9 0.1 2.1 2 0 0 2 2 2 0 SAMP Motif Glyco_hydro_43 PF04616.9 EPS34010.1 - 2.6e-32 112.0 1.4 3.5e-32 111.6 1.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 SGL PF08450.7 EPS34012.1 - 1.1e-26 93.7 0.1 2e-26 92.8 0.0 1.4 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 EPS34012.1 - 2.3e-06 27.4 0.1 1.3e-05 25.0 0.0 2.2 2 0 0 2 2 2 1 Arylesterase Str_synth PF03088.11 EPS34012.1 - 4.2e-06 26.7 0.0 2.2e-05 24.4 0.0 2.2 2 1 0 2 2 2 1 Strictosidine synthase NHL PF01436.16 EPS34012.1 - 0.0031 17.4 0.0 4.7 7.3 0.1 2.8 2 0 0 2 2 2 2 NHL repeat Pkinase PF00069.20 EPS34013.1 - 2.8e-71 239.7 0.0 5e-71 238.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS34013.1 - 4e-44 150.6 0.0 6.2e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EPS34013.1 - 1.4e-21 76.6 0.2 9.4e-21 74.0 0.0 2.7 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 EPS34013.1 - 1.8e-06 27.1 0.0 2.9e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EPS34013.1 - 0.024 14.3 0.0 0.29 10.8 0.0 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family DSHCT PF08148.7 EPS34013.1 - 0.075 12.2 0.0 0.17 11.0 0.0 1.5 1 0 0 1 1 1 0 DSHCT (NUC185) domain VHS PF00790.14 EPS34014.1 - 3e-37 127.3 0.5 5e-37 126.6 0.3 1.4 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.23 EPS34014.1 - 1e-16 60.0 0.1 6.3e-16 57.5 0.0 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EPS34014.1 - 1.2e-15 56.8 0.1 2.1e-15 56.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EPS34014.1 - 5.9e-15 54.4 0.0 1.2e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain UIM PF02809.15 EPS34014.1 - 0.018 14.5 1.3 0.048 13.2 0.9 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif adh_short PF00106.20 EPS34015.1 - 0.0043 16.9 0.0 0.014 15.3 0.0 1.7 1 1 1 2 2 2 1 short chain dehydrogenase UCH_1 PF13423.1 EPS34016.1 - 3.8e-70 236.6 0.8 5.1e-70 236.2 0.5 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 EPS34016.1 - 4.1e-21 75.9 0.0 1.1e-20 74.6 0.0 1.8 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 EPS34016.1 - 2.6e-07 30.0 0.0 1.7e-06 27.3 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase CcmH PF03918.9 EPS34016.1 - 0.061 12.3 0.1 0.12 11.3 0.1 1.3 1 0 0 1 1 1 0 Cytochrome C biogenesis protein GTP_EFTU PF00009.22 EPS34017.1 - 1.1e-50 171.7 0.0 1.8e-50 170.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 EPS34017.1 - 2.7e-16 59.4 2.6 5.9e-16 58.3 1.8 1.5 1 0 0 1 1 1 1 HBS1 N-terminus MMR_HSR1 PF01926.18 EPS34017.1 - 1.6e-08 34.4 0.3 1.3e-07 31.5 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D3 PF03143.12 EPS34017.1 - 1.8e-08 34.4 0.0 6.1e-08 32.7 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EPS34017.1 - 1.9e-08 34.3 0.0 5e-08 32.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 SRPRB PF09439.5 EPS34017.1 - 0.00026 20.2 0.1 0.042 13.0 0.0 2.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EPS34017.1 - 0.00074 19.9 0.6 0.0048 17.3 0.0 2.7 2 1 0 2 2 1 1 Miro-like protein Gtr1_RagA PF04670.7 EPS34017.1 - 0.0012 18.0 0.1 0.003 16.7 0.0 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EPS34017.1 - 0.0023 17.2 0.0 2.1 7.5 0.0 2.3 1 1 1 2 2 2 2 ADP-ribosylation factor family FeoB_N PF02421.13 EPS34017.1 - 0.038 13.2 0.3 1.1 8.5 0.2 2.8 2 1 0 2 2 2 0 Ferrous iron transport protein B Met_asp_mut_E PF06368.6 EPS34017.1 - 0.054 11.6 0.0 0.11 10.6 0.0 1.4 1 0 0 1 1 1 0 Methylaspartate mutase E chain (MutE) Septin PF00735.13 EPS34017.1 - 0.074 12.0 0.0 0.13 11.2 0.0 1.4 1 0 0 1 1 1 0 Septin RNA_pol_Rpc82 PF05645.8 EPS34017.1 - 0.085 12.3 0.0 0.085 12.3 0.0 2.3 3 0 0 3 3 3 0 RNA polymerase III subunit RPC82 HSP70 PF00012.15 EPS34018.1 - 2.4e-265 881.1 12.4 2.8e-265 880.9 8.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EPS34018.1 - 7.7e-18 64.1 0.7 1.6e-16 59.8 0.1 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 EPS34018.1 - 0.004 16.0 0.5 0.013 14.4 0.2 1.8 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 EPS34018.1 - 0.02 13.9 4.4 0.19 10.7 0.1 3.2 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase Drf_FH3 PF06367.11 EPS34018.1 - 0.07 12.5 3.4 0.28 10.5 1.2 2.3 2 0 0 2 2 2 0 Diaphanous FH3 Domain FtsA PF14450.1 EPS34018.1 - 1.7 8.4 6.1 3.8 7.3 0.1 3.5 2 1 0 2 2 2 0 Cell division protein FtsA DUF336 PF03928.9 EPS34019.1 - 3.8e-14 52.6 2.1 5e-13 49.0 0.9 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF336) Fungal_trans PF04082.13 EPS34021.1 - 2.3e-33 115.1 0.1 4.2e-33 114.3 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS34021.1 - 2e-06 27.6 14.1 5.9e-06 26.0 9.8 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_mis_repair PF01119.14 EPS34021.1 - 0.16 11.4 0.1 0.31 10.4 0.1 1.4 1 0 0 1 1 1 0 DNA mismatch repair protein, C-terminal domain Zn_clus PF00172.13 EPS34022.1 - 3.3e-05 23.6 13.5 5e-05 23.1 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MAD PF05557.8 EPS34022.1 - 0.064 11.3 0.9 0.077 11.0 0.6 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Enkurin PF13864.1 EPS34022.1 - 0.077 13.2 0.8 0.14 12.3 0.6 1.4 1 0 0 1 1 1 0 Calmodulin-binding Zip PF02535.17 EPS34022.1 - 0.12 11.4 5.0 0.13 11.2 3.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter bZIP_C PF12498.3 EPS34022.1 - 7.8 7.7 9.5 14 6.9 6.6 1.4 1 0 0 1 1 1 0 Basic leucine-zipper C terminal GFA PF04828.9 EPS34023.1 - 0.014 15.3 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme MSC PF09402.5 EPS34025.1 - 1e-100 336.7 0.0 1.7e-100 336.0 0.0 1.3 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 EPS34025.1 - 6.5e-16 57.5 0.1 1.3e-15 56.6 0.1 1.6 1 0 0 1 1 1 1 HeH/LEM domain PP2C PF00481.16 EPS34026.1 - 3e-48 164.4 0.0 5e-48 163.7 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 EPS34026.1 - 4.5e-44 147.4 58.8 1.3e-07 31.0 0.6 13.8 6 2 7 14 14 14 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EPS34026.1 - 7e-37 124.9 61.3 2.1e-07 30.5 0.1 11.9 6 4 5 13 13 13 10 Leucine rich repeat Guanylate_cyc PF00211.15 EPS34026.1 - 1.2e-25 89.9 0.0 2.4e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 EPS34026.1 - 6.9e-18 61.9 55.8 0.73 10.0 0.1 17.7 18 1 0 18 18 17 7 Leucine Rich Repeat LRR_7 PF13504.1 EPS34026.1 - 4.8e-11 40.9 37.3 2.8 8.5 0.1 14.8 14 1 0 14 14 14 4 Leucine rich repeat Ad_cyc_g-alpha PF08509.6 EPS34026.1 - 1.2e-05 24.5 0.0 3.3e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Adenylate cyclase G-alpha binding domain RA PF00788.18 EPS34026.1 - 4.8e-05 23.7 0.0 9.6e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_6 PF13516.1 EPS34026.1 - 0.0054 16.6 38.8 2.3 8.5 0.0 13.7 14 1 1 15 15 14 1 Leucine Rich repeat LRR_5 PF13306.1 EPS34026.1 - 0.0064 16.1 6.7 1.5 8.5 0.8 4.4 3 2 1 4 4 4 2 Leucine rich repeats (6 copies) LRR_9 PF14580.1 EPS34026.1 - 0.084 12.4 8.0 3.8 7.0 0.0 4.3 2 1 4 6 6 6 0 Leucine-rich repeat adh_short PF00106.20 EPS34027.1 - 3.5e-12 46.5 0.0 6.3e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPS34027.1 - 1.3e-05 24.9 0.1 1.9e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EPS34027.1 - 0.0083 15.0 0.0 0.014 14.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DUF1422 PF07226.6 EPS34027.1 - 0.029 14.0 0.2 0.058 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1422) Glyco_hydro_16 PF00722.16 EPS34028.1 - 2.3e-44 150.9 4.7 3.7e-44 150.2 3.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 His_Phos_1 PF00300.17 EPS34029.1 - 1.9e-21 76.8 0.0 2.3e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) MIP PF00230.15 EPS34030.1 - 8.1e-55 185.7 8.5 9.9e-55 185.4 5.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein FGGY_C PF02782.11 EPS34031.1 - 2.1e-72 242.9 0.4 3.3e-72 242.2 0.3 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EPS34031.1 - 8.6e-66 221.7 0.0 1.2e-65 221.2 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain p450 PF00067.17 EPS34032.1 - 4.5e-63 213.3 0.0 6.1e-63 212.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 IMS PF00817.15 EPS34033.1 - 3.9e-42 143.5 0.0 7.8e-42 142.5 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EPS34033.1 - 4.3e-19 68.7 0.0 8.8e-19 67.6 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 EPS34033.1 - 1.2e-17 63.7 5.0 6.8e-08 32.3 0.2 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF4414) IMS_HHH PF11798.3 EPS34033.1 - 2.4e-06 27.2 0.0 8.6e-06 25.5 0.0 2.1 1 0 0 1 1 1 1 IMS family HHH motif BRCT PF00533.21 EPS34033.1 - 2.1e-05 24.6 0.0 4.6e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EPS34033.1 - 5e-05 23.0 0.0 0.00011 22.0 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain HHH_5 PF14520.1 EPS34033.1 - 0.011 15.8 0.0 0.042 14.0 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain DUF1805 PF08827.6 EPS34033.1 - 0.09 12.5 0.0 0.27 11.0 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) FKBP_C PF00254.23 EPS34034.1 - 1.6e-31 108.1 0.0 6.3e-31 106.2 0.0 2.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase SDA1 PF05285.7 EPS34034.1 - 3.5 6.8 48.9 2.7 7.1 16.6 2.3 2 0 0 2 2 2 0 SDA1 Pkinase PF00069.20 EPS34035.1 - 4.9e-46 156.9 0.1 1.6e-24 86.4 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EPS34035.1 - 2.6e-20 72.5 0.1 9.1e-11 41.3 0.0 3.1 2 1 1 3 3 3 3 Protein tyrosine kinase APH PF01636.18 EPS34035.1 - 0.00046 19.9 0.1 0.0017 18.1 0.1 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EPS34035.1 - 0.16 10.7 0.0 0.25 10.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF3591 PF12157.3 EPS34036.1 - 8.6e-196 650.7 0.1 1.1e-195 650.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 EPS34036.1 - 0.0039 16.8 1.2 0.009 15.6 0.8 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EPS34036.1 - 0.015 15.1 0.9 0.026 14.4 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle GRASP55_65 PF04495.9 EPS34037.1 - 9.8e-43 145.4 0.0 2.6e-41 140.8 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain ApoO PF09769.4 EPS34038.1 - 3.3e-49 166.6 1.0 7.1e-49 165.5 0.1 1.9 3 0 0 3 3 3 1 Apolipoprotein O Peptidase_M3 PF01432.15 EPS34039.1 - 1.6e-119 400.0 0.0 2.5e-119 399.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 GTP1_OBG PF01018.17 EPS34041.1 - 2.2 7.9 7.9 2.5 7.7 5.5 1.3 1 1 0 1 1 1 0 GTP1/OBG Filament PF00038.16 EPS34042.1 - 0.32 10.4 172.3 0.03 13.7 3.2 7.5 1 1 4 6 6 6 0 Intermediate filament protein PTPA PF03095.10 EPS34045.1 - 1e-110 369.6 0.0 1.2e-110 369.4 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF572 PF04502.8 EPS34046.1 - 4.2e-58 197.0 0.2 5.4e-58 196.7 0.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) PAS_9 PF13426.1 EPS34048.1 - 4.6e-17 62.2 0.0 1.6e-16 60.5 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 EPS34048.1 - 0.015 15.0 0.0 0.031 14.0 0.0 1.5 1 0 0 1 1 1 0 PAS fold PAS_4 PF08448.5 EPS34048.1 - 0.023 14.7 0.0 0.087 12.8 0.0 2.0 2 0 0 2 2 2 0 PAS fold Sugar_tr PF00083.19 EPS34049.1 - 2.1e-79 267.2 22.2 2.4e-79 267.0 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS34049.1 - 1.3e-27 96.4 54.0 1.1e-25 90.1 17.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily GTP_EFTU PF00009.22 EPS34050.1 - 3e-31 108.3 0.0 4.1e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EPS34050.1 - 1.4e-13 50.8 0.0 3e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EPS34050.1 - 9.3e-09 35.2 0.0 2.2e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EPS34050.1 - 2.2e-05 24.4 0.0 5.7e-05 23.0 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EPS34050.1 - 0.00073 20.0 0.1 0.0048 17.3 0.0 2.3 2 1 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EPS34050.1 - 0.0096 15.7 0.8 0.38 10.5 0.1 2.3 1 1 1 2 2 2 1 Dynamin family FeoB_N PF02421.13 EPS34050.1 - 0.18 11.0 0.0 2.7 7.2 0.0 2.7 3 0 0 3 3 3 0 Ferrous iron transport protein B zf-CW PF07496.10 EPS34050.1 - 0.29 10.8 2.2 0.54 9.9 1.5 1.4 1 0 0 1 1 1 0 CW-type Zinc Finger APH PF01636.18 EPS34051.1 - 1.2e-08 34.9 0.0 2.1e-06 27.6 0.0 2.1 2 0 0 2 2 2 2 Phosphotransferase enzyme family EcKinase PF02958.15 EPS34051.1 - 0.0015 17.6 0.0 0.0022 17.1 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Excalibur PF05901.6 EPS34051.1 - 0.14 12.4 0.0 0.37 11.1 0.0 1.6 1 0 0 1 1 1 0 Excalibur calcium-binding domain Glyco_hydro_12 PF01670.11 EPS34052.1 - 2.5e-18 66.3 2.0 3.8e-18 65.7 1.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Glyco_tranf_2_3 PF13641.1 EPS34054.1 - 2.5e-36 125.6 0.0 3.8e-36 125.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EPS34054.1 - 5.8e-20 71.8 1.1 5.8e-20 71.8 0.7 2.3 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Cellulose_synt PF03552.9 EPS34054.1 - 4.5e-14 51.7 8.5 1.1e-09 37.1 1.5 3.9 2 1 2 4 4 4 2 Cellulose synthase Glyco_transf_21 PF13506.1 EPS34054.1 - 9.2e-12 44.5 0.0 1.4e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EPS34054.1 - 3.9e-10 39.6 0.0 6.3e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Chitin_synth_2 PF03142.10 EPS34054.1 - 0.011 14.1 0.1 0.03 12.7 0.0 1.7 2 0 0 2 2 2 0 Chitin synthase Glyco_tranf_2_2 PF10111.4 EPS34054.1 - 0.029 13.4 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 FAD_binding_7 PF03441.9 EPS34055.1 - 1.6e-91 306.3 1.2 2.3e-91 305.8 0.9 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EPS34055.1 - 1.1e-39 135.8 0.1 4e-39 134.0 0.0 1.8 2 0 0 2 2 2 1 DNA photolyase MFS_1 PF07690.11 EPS34056.1 - 2.8e-44 151.2 53.3 8e-44 149.7 34.9 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS34056.1 - 1.6e-18 66.5 34.8 1.2e-15 57.1 13.3 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 EPS34056.1 - 7.2e-15 54.2 16.0 7.2e-15 54.2 11.1 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_3 PF00933.16 EPS34057.1 - 1e-92 310.3 0.0 1.5e-92 309.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EPS34057.1 - 6.4e-55 186.1 0.3 5.5e-54 183.0 0.2 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EPS34057.1 - 3.7e-21 74.8 0.0 7.7e-21 73.8 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain AhpC-TSA PF00578.16 EPS34058.1 - 3.3e-32 110.7 0.0 4.4e-32 110.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 EPS34058.1 - 2.5e-13 49.4 0.3 4.1e-13 48.7 0.2 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 EPS34058.1 - 1.4e-12 47.4 0.0 1.8e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Redoxin Gly_transf_sug PF04488.10 EPS34059.1 - 2.6e-12 47.0 0.0 5.4e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EPS34059.1 - 0.0019 17.4 0.1 0.0028 16.8 0.0 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Methyltransf_15 PF09445.5 EPS34060.1 - 9.6e-48 161.8 0.0 1.2e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Met_10 PF02475.11 EPS34060.1 - 1.8e-09 37.4 0.0 2.4e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 EPS34060.1 - 3.1e-09 36.8 0.0 4.5e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EPS34060.1 - 2.8e-08 33.5 0.0 3.7e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_18 PF12847.2 EPS34060.1 - 8.7e-07 29.5 0.0 1.2e-06 29.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EPS34060.1 - 9.8e-06 25.0 0.0 1.3e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.1 EPS34060.1 - 1.8e-05 24.3 0.0 2.2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain DNA_methylase PF00145.12 EPS34060.1 - 0.024 13.7 0.0 0.035 13.2 0.0 1.2 1 0 0 1 1 1 0 C-5 cytosine-specific DNA methylase Methyltransf_21 PF05050.7 EPS34060.1 - 0.058 13.3 0.0 0.068 13.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase FkbM domain Methyltransf_5 PF01795.14 EPS34060.1 - 0.072 12.3 0.0 0.098 11.9 0.0 1.1 1 0 0 1 1 1 0 MraW methylase family MTS PF05175.9 EPS34060.1 - 0.074 12.4 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain bZIP_1 PF00170.16 EPS34061.1 - 0.00021 21.1 8.6 0.00021 21.1 6.0 1.5 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EPS34061.1 - 0.0025 17.5 7.7 0.0039 16.9 5.4 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EPS34061.1 - 0.059 13.6 2.2 0.11 12.7 1.5 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor CK_II_beta PF01214.13 EPS34063.1 - 7.4e-77 257.0 0.0 1.9e-76 255.6 0.0 1.6 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.3 EPS34063.1 - 0.0054 17.3 8.1 0.0054 17.3 5.6 2.3 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal Myc_N PF01056.13 EPS34063.1 - 8.1 5.4 9.5 0.62 9.1 1.9 2.0 2 0 0 2 2 2 0 Myc amino-terminal region Fungal_trans PF04082.13 EPS34064.1 - 2.2e-18 66.0 0.1 4.5e-18 65.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS34064.1 - 1.3e-07 31.4 13.6 2.2e-07 30.6 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_3 PF13738.1 EPS34065.1 - 1.3e-22 80.9 0.0 4.7e-22 79.0 0.0 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EPS34065.1 - 6.4e-08 31.2 0.4 5.4e-07 28.1 0.3 2.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EPS34065.1 - 9.7e-08 31.9 0.0 2.6e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EPS34065.1 - 6.6e-07 28.5 0.4 0.00013 21.0 0.1 3.1 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EPS34065.1 - 0.0087 15.1 0.0 0.023 13.7 0.0 1.7 1 0 0 1 1 1 1 Thi4 family Ret_tiss PF10044.4 EPS34065.1 - 0.089 13.3 0.0 0.31 11.5 0.0 1.9 1 0 0 1 1 1 0 Retinal tissue protein Shikimate_DH PF01488.15 EPS34065.1 - 0.16 12.0 0.0 14 5.8 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Cupin_8 PF13621.1 EPS34066.1 - 5.9e-28 98.0 0.0 1e-27 97.2 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EPS34066.1 - 8.3e-05 21.9 0.0 0.00027 20.2 0.0 1.8 3 0 0 3 3 3 1 Cupin superfamily protein Cupin_2 PF07883.6 EPS34066.1 - 0.043 13.3 0.0 0.16 11.4 0.0 1.9 2 0 0 2 2 2 0 Cupin domain Pkinase PF00069.20 EPS34067.1 - 3.5e-19 68.9 0.0 2.4e-18 66.2 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS34067.1 - 1.6e-07 30.6 0.0 3.3e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HrpA_pilin PF09589.5 EPS34068.1 - 0.058 13.8 1.8 0.15 12.4 1.3 2.1 1 1 0 1 1 1 0 HrpA pilus formation protein AA_permease PF00324.16 EPS34069.1 - 2.3e-99 332.9 42.4 7.7e-99 331.1 29.4 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPS34069.1 - 7.3e-15 54.4 35.2 1.4e-14 53.5 24.4 1.4 1 1 0 1 1 1 1 Amino acid permease zf-C2H2_2 PF12756.2 EPS34070.1 - 1.5e-35 121.3 21.2 2.7e-31 107.6 2.9 3.3 2 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EPS34070.1 - 1.2e-05 25.3 6.8 1.2e-05 25.3 4.7 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EPS34070.1 - 5.1e-05 23.3 5.9 5.1e-05 23.3 4.1 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type DUF2024 PF09630.5 EPS34070.1 - 0.033 13.9 3.3 4.1 7.1 0.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2024) Rotamase_2 PF13145.1 EPS34070.1 - 0.45 11.1 3.5 0.51 10.9 0.0 2.6 2 1 0 2 2 2 0 PPIC-type PPIASE domain HECT PF00632.20 EPS34071.1 - 3.6e-72 243.2 0.0 5.8e-72 242.5 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) FANCI_S2 PF14676.1 EPS34071.1 - 0.0071 16.2 0.0 0.022 14.6 0.0 1.8 1 0 0 1 1 1 1 FANCI solenoid 2 His_Phos_1 PF00300.17 EPS34072.1 - 8.3e-12 45.4 0.2 1.6e-11 44.5 0.0 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) 2-Hacid_dh_C PF02826.14 EPS34074.1 - 1.6e-53 180.5 0.0 2.5e-53 179.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EPS34074.1 - 3.2e-31 107.5 0.1 4.7e-31 107.0 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AlaDh_PNT_C PF01262.16 EPS34074.1 - 0.086 12.4 1.0 0.34 10.4 0.5 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Fungal_trans_2 PF11951.3 EPS34075.1 - 6.3e-09 34.9 0.1 9.1e-09 34.3 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS34075.1 - 3.8e-07 29.8 6.8 6.6e-07 29.1 4.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fe-ADH PF00465.14 EPS34076.1 - 6.1e-105 350.8 0.0 7.8e-105 350.5 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EPS34076.1 - 2.4e-15 56.5 0.0 2.5e-12 46.6 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.1 EPS34076.1 - 0.00037 19.9 0.0 0.00066 19.1 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein Toprim_3 PF13362.1 EPS34076.1 - 0.052 13.7 0.0 0.2 11.9 0.0 1.9 2 0 0 2 2 2 0 Toprim domain Bys1 PF04681.7 EPS34078.1 - 5.7e-10 39.1 0.1 7.9e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Rad10 PF03834.9 EPS34079.1 - 3.5e-31 106.7 0.0 5.6e-31 106.0 0.0 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 EPS34079.1 - 5.3e-06 26.5 0.0 9.6e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.18 EPS34079.1 - 0.00046 19.7 0.0 0.00091 18.8 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_2 PF12826.2 EPS34079.1 - 0.012 15.4 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif SART-1 PF03343.8 EPS34079.1 - 0.11 10.7 0.7 0.16 10.2 0.5 1.1 1 0 0 1 1 1 0 SART-1 family RRM_1 PF00076.17 EPS34080.1 - 2.1e-58 193.8 0.0 2.9e-17 62.0 0.1 5.6 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS34080.1 - 4.4e-40 135.4 0.0 9.3e-14 51.1 0.0 5.4 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS34080.1 - 7.7e-25 86.5 0.1 4.9e-10 39.0 0.0 4.7 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EPS34080.1 - 0.002 17.8 0.0 0.078 12.7 0.0 3.6 3 1 0 3 3 3 1 Limkain b1 Cyt-b5 PF00173.23 EPS34081.1 - 3.9e-11 42.5 0.0 4.6e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain APH PF01636.18 EPS34082.1 - 2.2e-08 34.1 0.0 4.6e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF21 PF01595.15 EPS34083.1 - 4.7e-32 110.7 0.3 8.5e-32 109.9 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EPS34083.1 - 1.1e-06 28.2 0.4 0.017 14.9 0.0 2.7 2 0 0 2 2 2 2 CBS domain DUF4372 PF14294.1 EPS34084.1 - 0.019 14.8 0.3 0.35 10.7 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4372) Transket_pyr PF02779.19 EPS34085.1 - 3.5e-44 150.4 0.0 5.2e-44 149.8 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EPS34085.1 - 3.5e-31 107.6 0.0 9.7e-31 106.2 0.0 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain Arginosuc_synth PF00764.14 EPS34086.1 - 4e-155 516.6 0.0 4.6e-155 516.4 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 EPS34086.1 - 0.00052 19.6 0.0 0.00072 19.1 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 EPS34086.1 - 0.014 14.7 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 EPS34086.1 - 0.039 12.5 0.0 0.057 11.9 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase PT PF04886.7 EPS34088.1 - 1e-07 31.1 19.6 5.7e-05 22.3 4.7 2.5 1 1 1 2 2 2 2 PT repeat Peptidase_M20 PF01546.23 EPS34089.1 - 4.3e-21 75.2 0.0 8.1e-20 71.1 0.0 2.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 EPS34089.1 - 1.5e-10 40.5 3.3 0.0089 15.8 0.0 5.9 5 1 0 5 5 5 3 WD domain, G-beta repeat M20_dimer PF07687.9 EPS34089.1 - 9e-07 28.6 0.0 1.8e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EPS34089.1 - 0.0092 15.7 0.0 0.023 14.4 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M28 Pkinase PF00069.20 EPS34090.1 - 2.3e-16 59.7 0.0 5.3e-16 58.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS34090.1 - 1.7e-08 33.8 0.0 7.9e-08 31.6 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Aminotran_4 PF01063.14 EPS34091.1 - 2.3e-30 105.7 0.0 3.2e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV Peptidase_M49 PF03571.10 EPS34092.1 - 2.7e-233 775.0 0.0 3.3e-233 774.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 SNF5 PF04855.7 EPS34094.1 - 6e-84 281.3 0.0 7.8e-84 280.9 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 EPS34094.1 - 0.00018 20.7 3.2 0.0002 20.6 1.1 2.1 1 1 1 2 2 2 1 GATA zinc finger TFIIA PF03153.8 EPS34096.1 - 2.8 7.7 22.7 3.5 7.4 15.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.27 EPS34097.1 - 2.8e-50 166.4 24.4 3.6e-13 48.8 0.2 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EPS34097.1 - 5.4e-06 26.2 13.5 0.0073 16.0 1.5 3.9 2 2 2 5 5 5 2 Transcription factor IIIC subunit delta N-term F-box-like PF12937.2 EPS34098.1 - 7.5e-07 28.7 0.0 1.9e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 F-box-like Sugar_tr PF00083.19 EPS34099.1 - 3e-107 359.0 14.7 3.5e-107 358.7 10.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS34099.1 - 1.2e-29 103.1 23.0 1.2e-29 103.1 16.0 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EPS34099.1 - 6.4e-07 27.9 5.4 1.3e-06 26.9 3.7 1.5 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) LacY_symp PF01306.14 EPS34099.1 - 0.00063 18.4 7.7 0.036 12.6 1.4 2.4 2 0 0 2 2 2 2 LacY proton/sugar symporter MFS_3 PF05977.8 EPS34099.1 - 0.0016 16.6 11.7 0.0039 15.3 1.1 2.6 2 1 0 2 2 2 2 Transmembrane secretion effector PspC PF04024.7 EPS34099.1 - 0.0044 16.4 0.4 0.0044 16.4 0.3 2.8 2 0 0 2 2 2 1 PspC domain MFS_1_like PF12832.2 EPS34099.1 - 0.0052 16.5 2.3 0.12 12.1 0.0 3.1 2 0 0 2 2 2 1 MFS_1 like family ABC_tran PF00005.22 EPS34100.1 - 2.4e-48 163.8 2.8 4e-23 82.2 0.0 3.2 3 1 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 EPS34100.1 - 1.8e-20 72.5 8.0 1.8e-20 72.5 5.5 4.1 5 0 0 5 5 4 1 ABC transporter AAA_21 PF13304.1 EPS34100.1 - 1.3e-15 58.1 0.5 0.0031 17.5 0.0 4.7 5 0 0 5 5 4 3 AAA domain SMC_N PF02463.14 EPS34100.1 - 1.1e-11 44.4 0.3 0.0044 16.2 0.0 4.5 4 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EPS34100.1 - 1.5e-09 38.6 0.2 0.0044 17.8 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 EPS34100.1 - 7.6e-07 28.5 0.1 0.058 12.9 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EPS34100.1 - 1.1e-06 27.9 0.1 0.022 13.9 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EPS34100.1 - 1.1e-06 28.7 0.0 0.018 15.1 0.0 3.2 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EPS34100.1 - 5e-06 26.4 0.1 0.033 14.1 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 EPS34100.1 - 6e-06 26.3 0.8 0.031 14.2 0.0 2.9 3 0 0 3 3 2 2 AAA ATPase domain AAA_18 PF13238.1 EPS34100.1 - 8.3e-06 26.1 4.7 0.067 13.5 0.0 3.8 5 0 0 5 5 3 2 AAA domain Miro PF08477.8 EPS34100.1 - 1.4e-05 25.5 0.1 0.046 14.2 0.0 3.0 2 0 0 2 2 2 1 Miro-like protein MobB PF03205.9 EPS34100.1 - 1.5e-05 24.7 0.0 0.04 13.6 0.1 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EPS34100.1 - 7.4e-05 22.7 2.9 0.19 11.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain Dynamin_N PF00350.18 EPS34100.1 - 0.00011 22.0 2.8 0.14 11.9 0.0 3.8 4 0 0 4 4 3 1 Dynamin family AAA_30 PF13604.1 EPS34100.1 - 0.00015 21.3 0.0 0.014 15.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EPS34100.1 - 0.00016 21.3 0.1 0.58 9.7 0.0 2.8 2 0 0 2 2 2 2 NACHT domain AAA_33 PF13671.1 EPS34100.1 - 0.00018 21.4 0.1 0.46 10.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EPS34100.1 - 0.00024 20.3 9.3 0.18 10.7 0.0 4.6 4 2 1 6 6 6 2 AAA ATPase domain AAA PF00004.24 EPS34100.1 - 0.00044 20.4 0.0 0.45 10.7 0.1 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 EPS34100.1 - 0.00064 20.1 21.2 0.0099 16.2 0.0 5.0 4 1 1 5 5 5 2 AAA domain AAA_14 PF13173.1 EPS34100.1 - 0.00067 19.5 0.0 2 8.2 0.0 3.0 2 0 0 2 2 2 2 AAA domain ArgK PF03308.11 EPS34100.1 - 0.0012 17.7 2.7 0.76 8.4 0.0 3.1 3 0 0 3 3 3 2 ArgK protein RNA_helicase PF00910.17 EPS34100.1 - 0.0016 18.5 0.0 1.1 9.4 0.0 2.7 2 0 0 2 2 2 1 RNA helicase ATP-synt_ab PF00006.20 EPS34100.1 - 0.005 16.3 0.0 0.8 9.1 0.0 2.6 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_25 PF13481.1 EPS34100.1 - 0.009 15.4 0.0 2.9 7.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EPS34100.1 - 0.01 15.3 1.6 1.3 8.4 0.2 2.7 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.1 EPS34100.1 - 0.01 15.7 0.1 9.8 6.1 0.1 3.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NTPase_1 PF03266.10 EPS34100.1 - 0.01 15.5 0.3 1.9 8.1 0.2 2.8 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.17 EPS34100.1 - 0.01 14.6 0.2 3.8 6.2 0.0 2.6 2 1 0 2 2 2 0 NB-ARC domain PduV-EutP PF10662.4 EPS34100.1 - 0.011 15.2 0.0 3.9 6.9 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Zeta_toxin PF06414.7 EPS34100.1 - 0.015 14.3 2.2 0.62 9.1 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin AAA_24 PF13479.1 EPS34100.1 - 0.016 14.8 0.1 2.7 7.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EPS34100.1 - 0.018 14.5 4.2 1.6 8.1 0.1 3.5 4 1 0 5 5 4 0 AAA-like domain SRP54 PF00448.17 EPS34100.1 - 0.018 14.5 0.2 0.93 8.9 0.0 2.9 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_5 PF07728.9 EPS34100.1 - 0.024 14.3 0.2 8.1 6.1 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.1 EPS34100.1 - 0.024 14.6 0.1 4.3 7.3 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.1 EPS34100.1 - 0.095 12.4 0.4 7.3 6.4 0.1 3.1 3 0 0 3 3 3 0 Part of AAA domain FeoB_N PF02421.13 EPS34100.1 - 0.11 11.7 0.3 3.8 6.7 0.0 2.8 3 0 0 3 3 3 0 Ferrous iron transport protein B PRK PF00485.13 EPS34100.1 - 0.27 10.7 2.9 0.36 10.3 0.0 2.6 4 0 0 4 4 3 0 Phosphoribulokinase / Uridine kinase family Seryl_tRNA_N PF02403.17 EPS34100.1 - 0.65 10.0 14.3 0.042 13.8 1.0 3.3 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DUF87 PF01935.12 EPS34100.1 - 0.93 9.2 0.0 0.93 9.2 0.0 4.6 6 1 0 6 6 5 0 Domain of unknown function DUF87 MadM PF03818.8 EPS34103.1 - 0.049 13.2 0.2 0.073 12.6 0.1 1.3 1 0 0 1 1 1 0 Malonate/sodium symporter MadM subunit 7tm_7 PF08395.7 EPS34103.1 - 0.18 10.8 7.5 0.23 10.4 5.2 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor Yip1 PF04893.12 EPS34103.1 - 0.44 10.0 9.4 0.49 9.8 6.5 1.1 1 0 0 1 1 1 0 Yip1 domain MFS_1 PF07690.11 EPS34104.1 - 1e-39 136.2 35.8 1e-39 136.2 24.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS34104.1 - 3e-11 42.5 9.4 3e-11 42.5 6.5 2.2 2 1 0 2 2 2 1 Sugar (and other) transporter Lamp PF01299.12 EPS34105.1 - 0.099 11.7 0.0 0.24 10.5 0.0 1.6 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) Glyco_transf_54 PF04666.8 EPS34106.1 - 4.7e-15 55.1 0.0 1.3e-11 43.8 0.0 3.1 2 1 0 2 2 2 2 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region TrbL PF04610.9 EPS34106.1 - 0.023 14.4 0.2 0.037 13.7 0.1 1.2 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein Na_Ca_ex PF01699.19 EPS34106.1 - 2.2 7.8 7.1 0.25 10.9 1.6 1.8 2 0 0 2 2 2 0 Sodium/calcium exchanger protein SKG6 PF08693.5 EPS34108.1 - 1.1e-08 34.2 5.1 1.1e-08 34.2 3.5 3.2 3 0 0 3 3 3 1 Transmembrane alpha-helix domain Rifin_STEVOR PF02009.11 EPS34108.1 - 7.2e-05 22.5 0.0 0.00014 21.6 0.0 1.4 1 1 0 1 1 1 1 Rifin/stevor family DUF4448 PF14610.1 EPS34108.1 - 0.0015 18.0 0.2 0.0026 17.2 0.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) DcuC PF03606.10 EPS34108.1 - 0.059 11.5 0.1 0.08 11.1 0.1 1.1 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier Peptidase_M56 PF05569.6 EPS34108.1 - 0.33 9.8 0.0 0.33 9.8 0.0 1.8 2 0 0 2 2 2 0 BlaR1 peptidase M56 TFIIA PF03153.8 EPS34108.1 - 0.69 9.7 13.0 1.1 9.0 9.0 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4366 PF14283.1 EPS34108.1 - 1.2 8.5 3.5 0.74 9.1 0.0 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4366) Ank_2 PF12796.2 EPS34109.1 - 7.3e-44 148.0 8.2 6.9e-14 51.9 0.2 3.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPS34109.1 - 2e-26 91.8 3.7 1.5e-08 34.9 0.0 6.6 2 1 7 9 9 9 7 Ankyrin repeats (many copies) Ank PF00023.25 EPS34109.1 - 1.9e-22 77.8 6.8 6.4e-05 22.5 0.0 7.9 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 EPS34109.1 - 1.3e-19 69.8 6.2 6.2e-06 26.2 0.0 5.9 1 1 6 7 7 7 5 Ankyrin repeats (many copies) SPX PF03105.14 EPS34109.1 - 2.6e-19 70.0 6.6 1.3e-15 57.9 4.6 2.2 1 1 0 1 1 1 1 SPX domain Ank_3 PF13606.1 EPS34109.1 - 8.8e-18 62.6 4.1 8.7e-05 22.4 0.0 7.7 9 0 0 9 9 9 4 Ankyrin repeat GDPD PF03009.12 EPS34109.1 - 2.8e-12 46.6 0.0 1e-11 44.8 0.0 1.8 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family DUF1279 PF06916.8 EPS34110.1 - 8e-29 99.7 0.0 1.3e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Ribosomal_L3 PF00297.17 EPS34111.1 - 3.8e-38 131.3 3.1 1.3e-36 126.3 2.1 2.1 1 1 0 1 1 1 1 Ribosomal protein L3 Coa1 PF08695.5 EPS34112.1 - 3.2e-42 142.7 0.1 4e-42 142.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 SUR7 PF06687.7 EPS34113.1 - 0.015 14.8 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 SUR7/PalI family DUF3040 PF11239.3 EPS34113.1 - 0.049 13.6 1.4 0.86 9.6 0.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) FA_desaturase PF00487.19 EPS34113.1 - 0.055 12.8 4.6 0.26 10.6 1.1 2.0 1 1 1 2 2 2 0 Fatty acid desaturase Enkurin PF13864.1 EPS34113.1 - 0.057 13.6 0.1 0.1 12.8 0.1 1.4 1 0 0 1 1 1 0 Calmodulin-binding JmjC PF02373.17 EPS34114.1 - 2.4e-09 37.4 0.4 9.9e-08 32.2 0.2 2.8 2 1 0 2 2 2 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.4 EPS34114.1 - 4e-08 33.3 10.2 4e-08 33.3 7.1 2.4 2 1 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.6 EPS34114.1 - 0.015 14.8 0.0 0.034 13.6 0.0 1.5 1 0 0 1 1 1 0 Cupin domain UbiA PF01040.13 EPS34115.1 - 2.4e-29 102.3 20.1 3.5e-29 101.8 13.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Glutaredoxin PF00462.19 EPS34116.1 - 1e-15 57.4 0.0 1.9e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin CTP_transf_2 PF01467.21 EPS34117.1 - 2.7e-16 60.0 0.0 1.1e-13 51.5 0.0 2.5 2 1 0 2 2 2 2 Cytidylyltransferase PRELI PF04707.9 EPS34119.1 - 2.6e-43 147.2 0.1 3e-43 147.0 0.1 1.0 1 0 0 1 1 1 1 PRELI-like family AhpC-TSA PF00578.16 EPS34120.1 - 3.6e-23 81.5 0.0 5.2e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EPS34120.1 - 1.3e-15 57.2 0.1 1.8e-15 56.7 0.1 1.2 1 0 0 1 1 1 1 Redoxin Nop14 PF04147.7 EPS34120.1 - 4.1 5.1 17.4 7.3 4.3 12.1 1.4 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EPS34120.1 - 7.2 4.5 12.7 9.5 4.1 8.8 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF1761 PF08570.5 EPS34122.1 - 1.8e-22 79.6 2.0 2.1e-22 79.4 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) QCR10 PF09796.4 EPS34122.1 - 3.6 7.3 5.2 2.9 7.6 0.2 2.8 1 1 2 3 3 3 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Methyltransf_16 PF10294.4 EPS34123.1 - 3.6e-51 173.0 0.0 4.5e-51 172.7 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EPS34123.1 - 0.00056 19.6 0.0 0.00081 19.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS34123.1 - 0.012 16.2 0.0 0.025 15.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EPS34123.1 - 0.072 12.6 0.0 0.13 11.8 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EPS34123.1 - 0.094 12.0 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Mpp10 PF04006.7 EPS34124.1 - 2.2e-90 303.8 54.6 2e-88 297.2 37.9 2.2 1 1 0 1 1 1 1 Mpp10 protein adh_short PF00106.20 EPS34125.1 - 9.7e-30 103.6 0.0 1.2e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPS34125.1 - 6.4e-27 94.8 0.0 7.7e-27 94.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPS34125.1 - 1.2e-13 51.1 0.0 1.6e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EPS34125.1 - 0.0067 16.1 0.1 0.013 15.3 0.1 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Oxidored_q6 PF01058.17 EPS34126.1 - 2.8e-22 78.7 0.1 4.9e-22 77.9 0.0 1.4 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Sedlin_N PF04628.8 EPS34127.1 - 3e-26 91.8 0.0 3.5e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Acyl_transf_1 PF00698.16 EPS34128.1 - 8.7e-26 90.9 0.0 1.9e-18 66.8 0.0 2.1 2 0 0 2 2 2 2 Acyl transferase domain Nucleoporin_C PF03177.9 EPS34129.1 - 7.2e-105 351.7 0.7 9.9e-105 351.2 0.5 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EPS34129.1 - 2.9e-60 204.2 0.0 3.8e-60 203.8 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like HABP4_PAI-RBP1 PF04774.10 EPS34130.1 - 0.01 16.3 3.4 0.016 15.7 2.3 1.4 1 1 0 1 1 1 0 Hyaluronan / mRNA binding family Strep_67kDa_ant PF06100.6 EPS34132.1 - 0.047 12.0 0.6 0.05 11.9 0.4 1.0 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family APH PF01636.18 EPS34135.1 - 3.4e-05 23.6 0.1 4.8e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family zf-ribbon_3 PF13248.1 EPS34136.1 - 0.097 11.9 0.2 2.2 7.5 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 EPS34136.1 - 0.11 12.2 0.5 0.2 11.3 0.3 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain APH PF01636.18 EPS34137.1 - 1.2e-10 41.5 1.0 1.4e-09 38.0 0.7 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EPS34137.1 - 0.00021 20.9 1.2 0.00068 19.2 0.5 1.9 1 1 1 2 2 2 1 Choline/ethanolamine kinase Borrelia_lipo_1 PF05714.6 EPS34141.1 - 0.037 13.1 4.0 0.96 8.4 2.3 2.3 1 1 0 1 1 1 0 Borrelia burgdorferi virulent strain associated lipoprotein PMEI PF04043.10 EPS34141.1 - 0.048 13.5 3.6 0.74 9.6 2.5 2.2 1 1 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor 4HB_MCP_1 PF12729.2 EPS34141.1 - 0.059 12.7 4.4 0.85 8.9 0.4 2.2 1 1 1 2 2 2 0 Four helix bundle sensory module for signal transduction COG2 PF06148.6 EPS34141.1 - 0.098 12.5 2.3 0.33 10.8 1.6 1.9 1 1 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 Inhibitor_I9 PF05922.11 EPS34142.1 - 0.077 13.5 0.2 0.12 12.9 0.1 1.4 1 1 0 1 1 1 0 Peptidase inhibitor I9 Rifin_STEVOR PF02009.11 EPS34142.1 - 0.15 11.6 4.6 0.15 11.6 3.2 1.0 1 0 0 1 1 1 0 Rifin/stevor family Flexi_CP PF00286.15 EPS34142.1 - 0.16 11.6 1.4 0.19 11.4 1.0 1.1 1 0 0 1 1 1 0 Viral coat protein Dicty_REP PF05086.7 EPS34142.1 - 2.3 5.8 7.4 2.4 5.8 5.2 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Tetrabrachion PF11401.3 EPS34143.1 - 0.054 13.2 1.1 0.14 11.9 0.8 1.8 1 1 0 1 1 1 0 Tetrabrachion Ribonuclease_3 PF00636.21 EPS34144.1 - 6.8e-15 55.5 0.0 2.2e-14 53.8 0.0 1.9 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EPS34144.1 - 3.1e-14 53.0 0.0 7.5e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 EPS34144.1 - 0.084 13.4 0.0 0.21 12.1 0.0 1.7 1 0 0 1 1 1 0 Double-stranded RNA binding motif MRP-S33 PF08293.6 EPS34145.1 - 3.1e-36 123.1 0.1 3.9e-36 122.9 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 EF_assoc_1 PF08355.7 EPS34145.1 - 0.087 12.1 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 EF hand associated ER_lumen_recept PF00810.13 EPS34146.1 - 4e-56 189.6 8.1 5.7e-56 189.0 5.6 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EPS34146.1 - 0.049 13.1 16.6 0.64 9.5 0.2 4.0 3 1 1 4 4 4 0 PQ loop repeat zf-H2C2 PF09337.5 EPS34147.1 - 0.019 14.3 0.4 0.034 13.5 0.3 1.4 1 0 0 1 1 1 0 His(2)-Cys(2) zinc finger XRCC4 PF06632.7 EPS34151.1 - 0.00019 20.3 5.6 0.00019 20.3 3.9 2.2 1 1 1 2 2 2 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF605 PF04652.11 EPS34151.1 - 1.4 8.2 26.9 1.9 7.7 18.6 1.2 1 0 0 1 1 1 0 Vta1 like Molybdopterin PF00384.17 EPS34152.1 - 3.7e-69 233.5 0.0 9.8e-35 120.1 0.0 2.2 1 1 1 2 2 2 2 Molybdopterin oxidoreductase Fer2_4 PF13510.1 EPS34152.1 - 1.7e-19 69.3 0.1 5.2e-19 67.8 0.1 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 EPS34152.1 - 2.9e-19 68.0 0.1 9.1e-19 66.4 0.1 1.9 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 EPS34152.1 - 1.4e-16 60.3 0.5 4.1e-16 58.8 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 EPS34152.1 - 1.7e-08 34.0 0.5 1.7e-08 34.0 0.4 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.22 EPS34152.1 - 0.1 12.2 1.0 3 7.5 0.2 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_19 PF06902.6 EPS34152.1 - 0.22 11.3 2.0 4 7.3 1.4 2.6 1 1 0 1 1 1 0 Divergent 4Fe-4S mono-cluster TPT PF03151.11 EPS34153.1 - 1.7e-36 125.2 3.4 1.7e-36 125.2 2.4 2.3 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EPS34153.1 - 1.2e-06 27.7 14.8 1.7e-05 23.9 10.3 2.1 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EPS34153.1 - 0.00012 22.1 34.2 0.0086 16.1 8.5 3.3 3 2 0 3 3 3 2 EamA-like transporter family PSII PF00421.14 EPS34153.1 - 0.12 10.9 1.4 0.2 10.1 1.0 1.3 1 0 0 1 1 1 0 Photosystem II protein PUF PF00806.14 EPS34154.1 - 2.5e-34 114.8 4.2 8.1e-07 28.1 0.0 8.2 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat Ssl1 PF04056.9 EPS34156.1 - 1.8e-75 252.7 0.0 2.4e-75 252.3 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 EPS34156.1 - 1.8e-17 63.0 7.9 1.8e-17 63.0 5.5 2.3 2 1 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 EPS34156.1 - 1e-10 42.0 0.0 1.5e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EPS34156.1 - 0.0047 16.6 0.0 0.0074 16.0 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.9 EPS34156.1 - 0.017 14.3 1.1 0.032 13.4 0.8 1.5 1 0 0 1 1 1 0 Transcription factor Tfb4 DZR PF12773.2 EPS34156.1 - 0.36 10.6 22.2 1.1 9.1 3.9 3.4 2 1 1 3 3 3 0 Double zinc ribbon TF_Zn_Ribbon PF08271.7 EPS34156.1 - 8.6 5.7 10.4 1.9 7.9 0.9 3.5 3 0 0 3 3 3 0 TFIIB zinc-binding Peptidase_M1 PF01433.15 EPS34157.1 - 8.4e-128 426.7 0.5 2e-127 425.5 0.2 1.7 2 0 0 2 2 2 1 Peptidase family M1 ERAP1_C PF11838.3 EPS34157.1 - 2.8e-74 250.2 1.7 4.7e-74 249.5 1.2 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EPS34157.1 - 6.3e-17 61.8 1.4 1.4e-16 60.7 1.0 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily Ras PF00071.17 EPS34158.1 - 7.5e-66 220.4 0.5 8.8e-66 220.2 0.4 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPS34158.1 - 1.1e-21 77.5 0.0 1.7e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPS34158.1 - 2e-16 59.7 0.1 2.4e-16 59.4 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EPS34158.1 - 1.8e-05 23.9 0.1 2.4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EPS34158.1 - 4.1e-05 23.1 0.1 8.4e-05 22.0 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EPS34158.1 - 6.3e-05 22.9 0.0 9.1e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.24 EPS34158.1 - 0.00031 20.9 0.1 0.12 12.6 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.5 EPS34158.1 - 0.00073 18.8 0.0 0.001 18.3 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EPS34158.1 - 0.0013 18.8 0.0 0.0026 17.9 0.0 1.7 1 1 1 2 2 2 1 AAA domain FeoB_N PF02421.13 EPS34158.1 - 0.0041 16.4 0.0 0.029 13.6 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 EPS34158.1 - 0.0092 15.1 0.0 0.024 13.8 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EPS34158.1 - 0.02 14.8 0.1 0.084 12.8 0.0 1.9 1 1 0 2 2 2 0 AAA ATPase domain AAA_14 PF13173.1 EPS34158.1 - 0.03 14.2 0.1 0.09 12.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 EPS34158.1 - 0.032 13.2 0.1 0.2 10.6 0.0 2.0 2 0 0 2 2 2 0 Septin AAA_29 PF13555.1 EPS34158.1 - 0.039 13.4 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EPS34158.1 - 0.053 13.2 0.1 0.1 12.3 0.0 1.7 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 EPS34158.1 - 0.056 13.7 0.1 0.13 12.5 0.0 1.8 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 EPS34158.1 - 0.086 12.3 0.1 0.89 9.0 0.0 2.2 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Mito_carr PF00153.22 EPS34159.1 - 5.8e-54 179.7 3.1 6.8e-18 64.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.11 EPS34159.1 - 0.0013 18.5 0.3 0.0038 17.0 0.2 1.8 2 0 0 2 2 2 1 UcrQ family AphA_like PF14557.1 EPS34159.1 - 0.0017 17.9 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 Putative AphA-like transcriptional regulator HMD PF03201.11 EPS34159.1 - 0.078 12.9 0.0 6 6.8 0.0 3.1 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase WD40 PF00400.27 EPS34160.1 - 2.6e-09 36.5 9.0 0.0064 16.3 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat WW PF00397.21 EPS34161.1 - 7.2e-09 35.3 4.0 1.4e-08 34.4 2.8 1.5 1 0 0 1 1 1 1 WW domain DUF2012 PF09430.5 EPS34162.1 - 2.2e-30 104.9 0.0 3.1e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) HLH PF00010.21 EPS34165.1 - 9.3e-14 50.8 0.7 2e-13 49.7 0.5 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3439 PF11921.3 EPS34165.1 - 2.5 7.8 16.2 3 7.6 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) RNA_pol_Rpc82 PF05645.8 EPS34166.1 - 1.6e-29 103.2 0.0 1.1e-24 87.4 0.0 2.7 2 2 0 2 2 2 2 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 EPS34166.1 - 1.3e-16 60.2 0.8 8e-09 35.2 0.0 3.9 4 0 0 4 4 4 3 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 EPS34166.1 - 0.0002 20.8 0.1 0.0022 17.5 0.0 2.5 2 0 0 2 2 2 1 TFIIE alpha subunit Peptidase_M16 PF00675.15 EPS34167.1 - 8.3e-20 71.0 0.0 1.5e-19 70.2 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EPS34167.1 - 6.9e-14 51.9 0.1 2.1e-13 50.3 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain DUF2303 PF10065.4 EPS34169.1 - 0.16 10.7 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2303) Mito_carr PF00153.22 EPS34170.1 - 1.1e-27 95.5 6.1 1.3e-12 47.2 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Citrate_synt PF00285.16 EPS34171.1 - 1.4e-100 336.5 0.0 1.7e-100 336.2 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase Amidohydro_1 PF01979.15 EPS34171.1 - 0.12 12.0 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Amidohydrolase family DUF2740 PF10872.3 EPS34171.1 - 0.21 11.2 0.8 0.5 10.0 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2740) RRM_1 PF00076.17 EPS34172.1 - 3.6e-05 23.3 0.0 6e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 EPS34172.1 - 0.00059 20.0 0.0 0.0023 18.1 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase II-binding domain. RRM_5 PF13893.1 EPS34172.1 - 0.0049 16.6 0.0 0.0095 15.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS34172.1 - 0.0073 16.2 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) AA_permease_2 PF13520.1 EPS34174.1 - 9.7e-55 185.8 56.4 1.2e-54 185.5 39.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPS34174.1 - 8.1e-20 70.6 47.4 1.1e-19 70.2 32.8 1.1 1 0 0 1 1 1 1 Amino acid permease TMEM61 PF15105.1 EPS34174.1 - 0.096 12.2 0.2 14 5.1 0.0 2.3 2 0 0 2 2 2 0 TMEM61 protein family Hexokinase_1 PF00349.16 EPS34175.1 - 5.4e-56 189.1 0.0 9.1e-56 188.4 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 EPS34175.1 - 8.5e-52 175.7 0.1 1.3e-40 139.1 0.1 2.2 2 0 0 2 2 2 2 Hexokinase Cys_Met_Meta_PP PF01053.15 EPS34177.1 - 3.3e-147 489.8 0.0 3.7e-147 489.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EPS34177.1 - 4.6e-14 52.2 1.2 5.9e-14 51.8 0.4 1.4 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EPS34177.1 - 9.7e-10 37.9 0.1 1.9e-09 36.9 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EPS34177.1 - 1.1e-05 24.7 0.0 1.9e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EPS34177.1 - 1.4e-05 24.0 0.1 2.5e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.6 EPS34177.1 - 0.00054 18.3 0.1 0.00073 17.9 0.0 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase SLA_LP_auto_ag PF05889.8 EPS34177.1 - 0.084 11.3 0.0 0.12 10.7 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) GDC-P PF02347.11 EPS34177.1 - 0.085 11.5 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein MARVEL PF01284.18 EPS34178.1 - 7.9e-23 80.8 19.1 9.3e-23 80.6 13.2 1.0 1 0 0 1 1 1 1 Membrane-associating domain AA_permease PF00324.16 EPS34179.1 - 3.4e-132 441.1 47.4 4.1e-132 440.9 32.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPS34179.1 - 1.2e-33 116.3 52.6 1.4e-33 116.0 36.5 1.1 1 0 0 1 1 1 1 Amino acid permease AMP-binding PF00501.23 EPS34180.1 - 1.4e-83 280.6 0.0 1.7e-83 280.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Septin PF00735.13 EPS34182.1 - 4.1e-14 52.2 0.0 7.9e-13 48.0 0.0 2.1 1 1 0 1 1 1 1 Septin AAA PF00004.24 EPS34182.1 - 0.0051 17.0 0.0 0.0092 16.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 EPS34182.1 - 0.0092 16.4 0.0 0.025 15.0 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EPS34182.1 - 0.011 15.7 0.0 0.027 14.4 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.1 EPS34182.1 - 0.014 15.3 0.0 0.042 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 EPS34182.1 - 0.014 15.2 0.1 0.045 13.6 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_17 PF13207.1 EPS34182.1 - 0.016 16.0 0.0 0.057 14.2 0.0 2.0 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.16 EPS34182.1 - 0.019 14.1 0.0 0.037 13.1 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EPS34182.1 - 0.022 14.5 0.1 0.054 13.2 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Dynamin_N PF00350.18 EPS34182.1 - 0.022 14.5 0.1 5.9 6.6 0.0 2.4 2 0 0 2 2 2 0 Dynamin family ABC_tran PF00005.22 EPS34182.1 - 0.026 14.8 0.0 0.056 13.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.13 EPS34182.1 - 0.027 13.9 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 EPS34182.1 - 0.036 13.1 0.0 0.11 11.5 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin DUF815 PF05673.8 EPS34182.1 - 0.037 12.9 0.0 0.059 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.1 EPS34182.1 - 0.06 13.4 0.0 0.29 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EPS34182.1 - 0.089 11.6 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.1 EPS34182.1 - 0.095 12.2 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EPS34182.1 - 0.1 12.0 0.0 0.29 10.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EPS34182.1 - 0.1 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.1 EPS34182.1 - 0.1 12.1 1.2 0.19 11.2 0.1 1.9 2 0 0 2 2 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 EPS34182.1 - 0.18 10.9 0.0 0.34 10.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 EPS34182.1 - 0.19 11.3 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EPS34182.1 - 0.19 11.4 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 NTPase MobB PF03205.9 EPS34182.1 - 0.21 11.3 0.1 0.39 10.4 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B TIP49 PF06068.8 EPS34182.1 - 0.24 10.0 0.0 0.35 9.5 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus ABM PF03992.11 EPS34184.1 - 0.00023 21.1 0.1 0.00031 20.7 0.1 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF482 PF04339.7 EPS34184.1 - 0.021 13.6 0.1 0.023 13.5 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF482 SelP_N PF04592.9 EPS34184.1 - 0.074 12.4 0.3 0.083 12.2 0.2 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region HSP90 PF00183.13 EPS34185.1 - 6.1e-256 849.9 34.7 7.4e-256 849.6 24.1 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 EPS34185.1 - 2.7e-11 43.1 0.1 4.8e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EPS34185.1 - 4.5e-11 42.5 0.2 4.5e-11 42.5 0.1 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF1510 PF07423.6 EPS34185.1 - 4.7 6.5 26.8 0.14 11.4 12.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Tom37_C PF11801.3 EPS34185.1 - 7.4 6.4 12.2 9.2 6.0 3.6 2.8 2 0 0 2 2 2 0 Tom37 C-terminal domain NTF2 PF02136.15 EPS34186.1 - 2.9e-24 85.7 0.1 5.1e-24 84.9 0.1 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 EPS34186.1 - 5e-06 26.0 0.0 9.2e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS34186.1 - 4.9e-05 23.2 0.0 8.7e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS34186.1 - 0.00071 19.3 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EPS34186.1 - 0.039 13.8 0.0 0.039 13.8 0.0 2.6 3 0 0 3 3 3 0 RNA binding motif TPR_11 PF13414.1 EPS34188.1 - 0.025 14.2 17.7 1.3 8.7 0.3 5.2 4 2 0 4 4 4 0 TPR repeat TPR_12 PF13424.1 EPS34188.1 - 8.5 6.3 13.0 9.9 6.1 0.3 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat Nnf1 PF03980.9 EPS34189.1 - 1.1e-30 105.7 3.5 1.3e-30 105.5 1.9 1.5 1 1 1 2 2 2 1 Nnf1 TACC PF05010.9 EPS34189.1 - 2.7e-05 24.0 2.2 0.023 14.4 0.0 2.2 2 0 0 2 2 2 2 Transforming acidic coiled-coil-containing protein (TACC) Apolipoprotein PF01442.13 EPS34189.1 - 0.001 18.6 3.0 0.001 18.6 2.1 2.0 2 0 0 2 2 2 1 Apolipoprotein A1/A4/E domain KfrA_N PF11740.3 EPS34189.1 - 0.048 14.1 12.1 0.53 10.7 1.2 2.4 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term DUF948 PF06103.6 EPS34189.1 - 0.048 13.5 0.8 0.11 12.3 0.2 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FlgN PF05130.7 EPS34189.1 - 0.077 13.2 11.2 0.48 10.6 7.8 2.0 1 1 0 1 1 1 0 FlgN protein SNARE PF05739.14 EPS34189.1 - 0.14 11.8 3.1 0.16 11.6 1.1 1.9 2 0 0 2 2 2 0 SNARE domain BLOC1_2 PF10046.4 EPS34189.1 - 0.2 11.8 2.6 0.33 11.0 0.3 2.0 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Metal_resist PF13801.1 EPS34189.1 - 0.23 11.4 6.8 0.65 9.9 1.4 2.8 2 2 1 3 3 3 0 Heavy-metal resistance Syntaxin-6_N PF09177.6 EPS34189.1 - 0.91 9.9 6.7 0.3 11.5 0.7 2.3 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF972 PF06156.8 EPS34189.1 - 1.1 9.6 3.6 11 6.4 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) COG2 PF06148.6 EPS34189.1 - 1.5 8.6 7.5 0.46 10.3 1.0 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CR6_interact PF10147.4 EPS34189.1 - 2.8 7.1 9.5 0.8 8.9 1.1 2.3 2 1 0 2 2 2 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 IFT57 PF10498.4 EPS34189.1 - 4.6 5.8 7.1 0.34 9.5 1.3 1.6 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 7tm_2 PF00002.19 EPS34190.1 - 2.9e-11 42.9 5.6 5.7e-11 41.9 3.9 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 EPS34190.1 - 4.3e-09 35.6 17.7 2e-08 33.5 6.0 2.1 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor Git3 PF11710.3 EPS34190.1 - 0.00011 21.7 8.9 0.00011 21.7 6.2 1.8 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 Pkinase PF00069.20 EPS34191.1 - 3.5e-76 255.8 0.0 4.3e-76 255.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS34191.1 - 1.1e-36 126.2 0.0 1.6e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPS34191.1 - 0.00071 18.6 0.8 0.005 15.8 0.0 2.5 1 1 0 3 3 3 1 Kinase-like APH PF01636.18 EPS34191.1 - 0.027 14.2 0.9 0.089 12.5 0.0 2.1 2 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EPS34191.1 - 0.044 12.8 0.1 0.044 12.8 0.1 2.0 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EPS34191.1 - 0.077 11.8 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 SIR2 PF02146.12 EPS34192.1 - 3.6e-31 108.2 0.0 5.4e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 Sir2 family Cation_efflux PF01545.16 EPS34193.1 - 1e-62 211.7 0.8 1.2e-62 211.5 0.5 1.1 1 0 0 1 1 1 1 Cation efflux family TrkH PF02386.11 EPS34193.1 - 0.017 13.7 0.3 0.025 13.1 0.2 1.2 1 0 0 1 1 1 0 Cation transport protein FGGY_C PF02782.11 EPS34194.1 - 1.1e-33 116.5 0.0 2e-33 115.6 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EPS34194.1 - 1.4e-21 76.9 0.0 1.2e-14 54.2 0.0 2.4 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Xpo1 PF08389.7 EPS34195.1 - 6.6e-41 139.6 0.2 6e-40 136.5 0.0 2.9 3 0 0 3 3 3 1 Exportin 1-like protein HEAT PF02985.17 EPS34195.1 - 0.0023 17.8 5.4 15 5.9 0.0 6.1 7 0 0 7 7 7 2 HEAT repeat Esterase PF00756.15 EPS34196.1 - 4e-54 183.6 0.1 4.9e-54 183.3 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 EPS34196.1 - 5.6e-07 29.4 0.0 7.6e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 EPS34196.1 - 1.2e-06 27.9 0.0 7e-05 22.1 0.0 2.1 2 0 0 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EPS34196.1 - 2.5e-05 23.5 0.2 4e-05 22.9 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EPS34196.1 - 7.7e-05 22.6 0.0 0.00014 21.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EPS34196.1 - 0.0014 17.6 0.0 0.0026 16.7 0.0 1.4 1 1 0 1 1 1 1 Chlorophyllase enzyme Lipase_3 PF01764.20 EPS34196.1 - 0.0051 16.4 0.0 0.0082 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 EPS34196.1 - 0.0099 15.4 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.8 EPS34196.1 - 0.021 14.3 0.0 0.046 13.2 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EPS34196.1 - 0.024 14.2 0.0 0.45 10.0 0.0 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold AXE1 PF05448.7 EPS34196.1 - 0.067 11.6 0.0 0.096 11.1 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 EPS34196.1 - 0.071 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Chlorophyllase PF07224.6 EPS34196.1 - 0.094 11.4 0.0 0.33 9.6 0.0 1.7 2 0 0 2 2 2 0 Chlorophyllase Peptidase_C50 PF03568.12 EPS34197.1 - 5.8e-129 430.1 0.0 9.6e-129 429.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family C50 TPR_12 PF13424.1 EPS34197.1 - 5.2e-07 29.4 22.2 0.02 14.8 0.8 7.2 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 EPS34197.1 - 1.2e-06 27.9 6.4 1.2 9.1 0.1 6.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 EPS34197.1 - 1.3e-05 24.5 2.1 4.3 7.1 0.1 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 EPS34197.1 - 0.00086 18.9 9.3 6.5 6.4 0.0 6.3 6 1 0 6 6 6 1 TPR repeat TPR_8 PF13181.1 EPS34197.1 - 0.012 15.3 0.9 21 5.2 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EPS34197.1 - 0.11 13.2 19.7 2.9 8.7 0.0 7.5 7 0 0 7 7 7 0 Tetratricopeptide repeat SPT16 PF08644.6 EPS34197.1 - 0.93 9.3 4.1 12 5.6 0.0 3.1 3 1 0 3 3 3 0 FACT complex subunit (SPT16/CDC68) HXXSHH PF07586.6 EPS34198.1 - 0.1 11.5 2.2 0.16 10.8 1.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1552) Mito_carr PF00153.22 EPS34199.1 - 9.4e-75 246.4 0.1 8e-26 89.5 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 EPS34199.1 - 1.4e-15 55.3 0.1 4.8e-08 31.7 0.0 5.2 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.1 EPS34199.1 - 6e-15 53.7 0.2 1.8e-07 30.4 0.0 5.3 5 0 0 5 5 5 2 EF-hand domain EF-hand_8 PF13833.1 EPS34199.1 - 1.3e-13 50.3 0.3 0.073 12.7 0.0 5.5 3 3 2 5 5 5 5 EF-hand domain pair EF-hand_7 PF13499.1 EPS34199.1 - 4.9e-13 49.0 2.4 9.6e-08 32.0 0.7 3.7 3 2 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 EPS34199.1 - 2.3e-10 39.3 0.9 1.1e-06 27.6 0.0 4.5 5 0 0 5 5 5 1 EF hand PAP2_3 PF14378.1 EPS34200.1 - 6.8e-41 139.8 12.0 9.2e-41 139.4 8.3 1.2 1 0 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.16 EPS34200.1 - 0.00024 20.7 12.2 0.00052 19.6 6.8 2.3 1 1 1 2 2 2 2 PAP2 superfamily PAP2_C PF14360.1 EPS34200.1 - 0.017 15.3 1.9 0.017 15.3 1.3 2.5 2 0 0 2 2 2 0 PAP2 superfamily C-terminal F-box-like PF12937.2 EPS34201.1 - 0.14 11.9 0.5 0.41 10.3 0.0 2.1 3 0 0 3 3 3 0 F-box-like YwqJ-deaminase PF14431.1 EPS34203.1 - 0.03 14.1 0.0 0.053 13.3 0.0 1.3 1 0 0 1 1 1 0 YwqJ-like deaminase PAP2 PF01569.16 EPS34203.1 - 3.6 7.2 9.1 0.67 9.6 0.6 2.9 3 0 0 3 3 3 0 PAP2 superfamily Peptidase_M22 PF00814.20 EPS34204.1 - 8.4e-42 143.5 0.0 5.2e-41 140.9 0.0 2.1 1 1 0 1 1 1 1 Glycoprotease family YycC PF14174.1 EPS34204.1 - 0.052 13.2 0.0 0.096 12.3 0.0 1.4 1 0 0 1 1 1 0 YycC-like protein zf-HC5HC2H_2 PF13832.1 EPS34206.1 - 6.6e-32 109.7 5.2 6.6e-32 109.7 3.6 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain EPL1 PF10513.4 EPS34206.1 - 1.8e-29 103.0 0.0 3.7e-29 102.0 0.0 1.6 1 0 0 1 1 1 1 Enhancer of polycomb-like zf-HC5HC2H PF13771.1 EPS34206.1 - 1.5e-26 92.3 1.5 1.5e-26 92.3 1.1 3.1 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.1 EPS34206.1 - 5.4e-15 54.4 8.9 6.7e-14 50.9 1.7 2.5 2 0 0 2 2 2 2 PHD-finger PHD PF00628.24 EPS34206.1 - 6.6e-10 38.5 20.5 5.4e-08 32.4 6.7 2.7 2 0 0 2 2 2 2 PHD-finger C1_1 PF00130.17 EPS34206.1 - 0.7 9.6 19.5 0.034 13.8 1.1 2.8 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.6 EPS34206.1 - 3.2 7.8 20.4 0.053 13.5 2.8 2.7 2 0 0 2 2 2 0 RING-like domain zf-PHD-like PF15446.1 EPS34206.1 - 5.3 6.2 11.9 0.04 13.2 2.0 2.0 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain RRM_1 PF00076.17 EPS34207.1 - 2e-20 72.1 0.0 2.9e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS34207.1 - 3e-16 59.1 0.0 4.9e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS34207.1 - 2.2e-11 43.4 0.0 3.1e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dpy-30 PF05186.8 EPS34208.1 - 7.6e-14 50.9 0.1 1e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif VRR_NUC PF08774.6 EPS34209.1 - 6e-17 61.5 0.1 2.7e-16 59.4 0.0 2.2 3 0 0 3 3 3 1 VRR-NUC domain Ribosomal_S13_N PF08069.7 EPS34210.1 - 2e-28 97.9 0.0 3.7e-28 97.1 0.0 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EPS34210.1 - 1e-21 76.4 0.0 1.6e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 EPS34210.1 - 0.0089 15.7 0.1 0.02 14.6 0.0 1.6 2 0 0 2 2 2 1 'Paired box' domain OGG_N PF07934.7 EPS34211.1 - 8.6e-34 116.0 0.1 1.9e-33 114.9 0.1 1.6 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 EPS34211.1 - 4.8e-16 58.9 0.0 8.9e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EPS34211.1 - 0.014 15.0 0.0 0.031 13.9 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif RRM_1 PF00076.17 EPS34212.1 - 1.5e-26 91.7 0.1 9.4e-12 44.4 0.0 3.9 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS34212.1 - 2.3e-19 69.1 0.0 0.00011 22.0 0.0 3.6 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS34212.1 - 3e-14 52.6 0.0 2.2e-07 30.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GMC_oxred_N PF00732.14 EPS34213.1 - 1e-28 100.3 0.0 1.7e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EPS34213.1 - 3.5e-18 66.2 0.4 6.5e-18 65.4 0.3 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EPS34213.1 - 4e-11 42.4 0.2 0.00015 20.8 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EPS34213.1 - 2.3e-07 30.0 0.4 0.0018 17.1 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.9 EPS34213.1 - 1.5e-06 26.9 0.3 1.5e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 EPS34213.1 - 2.2e-05 24.3 0.1 0.00012 21.9 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EPS34213.1 - 2.3e-05 23.6 0.1 0.00035 19.7 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EPS34213.1 - 0.0005 19.9 2.1 0.0054 16.6 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EPS34213.1 - 0.00098 19.2 0.0 0.25 11.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EPS34213.1 - 0.0025 16.9 0.1 0.0043 16.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EPS34213.1 - 0.0043 16.1 0.1 0.01 14.9 0.0 1.6 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EPS34213.1 - 0.0043 17.4 1.2 0.021 15.2 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EPS34213.1 - 0.042 12.7 0.3 0.09 11.6 0.0 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 EPS34213.1 - 0.091 11.3 0.1 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Lycopene_cycl PF05834.7 EPS34213.1 - 0.1 11.5 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Tannase PF07519.6 EPS34214.1 - 3.8e-120 401.7 3.8 5.3e-120 401.3 2.6 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 EPS34214.1 - 2.3e-05 24.1 0.1 0.0046 16.7 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPS34214.1 - 0.001 19.0 0.0 0.0022 17.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPS34214.1 - 0.0014 18.1 0.0 0.0023 17.5 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Zn_clus PF00172.13 EPS34215.1 - 4.6e-07 29.6 11.6 9.6e-07 28.6 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EPS34215.1 - 4.3e-06 25.5 0.2 4.7e-05 22.1 0.1 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain TAF1D PF15333.1 EPS34216.1 - 0.2 11.4 3.6 0.23 11.2 2.5 1.1 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D 7tm_2 PF00002.19 EPS34217.1 - 1.4e-06 27.5 12.1 3.3e-05 23.0 9.1 1.8 1 1 1 2 2 2 2 7 transmembrane receptor (Secretin family) RskA PF10099.4 EPS34217.1 - 0.31 10.7 3.1 0.34 10.6 0.8 2.0 1 1 1 2 2 2 0 Anti-sigma-K factor rskA H_PPase PF03030.11 EPS34217.1 - 0.59 8.3 3.7 0.4 8.8 0.7 1.9 2 1 0 2 2 2 0 Inorganic H+ pyrophosphatase Abhydrolase_6 PF12697.2 EPS34218.1 - 5.4e-25 88.5 2.6 6.8e-25 88.2 1.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPS34218.1 - 2.5e-10 40.2 1.6 4.1e-09 36.3 1.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPS34218.1 - 0.0057 16.2 0.6 0.18 11.2 0.1 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_8 PF06259.7 EPS34218.1 - 0.05 13.1 0.1 0.079 12.4 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF900 PF05990.7 EPS34218.1 - 0.11 11.7 0.2 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.8 EPS34218.1 - 0.14 11.7 0.8 0.23 11.0 0.6 1.3 1 0 0 1 1 1 0 PGAP1-like protein UPF0121 PF03661.8 EPS34219.1 - 2.2e-13 50.0 2.8 2.9e-13 49.5 2.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Spo7 PF03907.8 EPS34219.1 - 2.6 7.5 6.0 0.72 9.4 1.0 2.2 2 1 1 3 3 3 0 Spo7-like protein Rax2 PF12768.2 EPS34220.1 - 3e-101 338.3 12.0 7.8e-93 310.7 0.0 5.7 4 1 2 6 6 6 4 Cortical protein marker for cell polarity Kelch_6 PF13964.1 EPS34220.1 - 0.05 13.7 7.2 10 6.4 0.1 5.2 6 0 0 6 6 6 0 Kelch motif Kelch_2 PF07646.10 EPS34220.1 - 7 6.5 6.6 17 5.3 0.0 4.3 5 0 0 5 5 5 0 Kelch motif SSrecog PF03531.9 EPS34222.1 - 4.1e-73 245.3 0.7 5.6e-72 241.6 0.5 2.2 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EPS34222.1 - 3e-28 97.6 0.0 3e-27 94.4 0.0 2.5 3 0 0 3 3 3 1 Histone chaperone Rttp106-like DUF2201_N PF13203.1 EPS34222.1 - 0.13 11.4 0.1 0.13 11.4 0.1 2.3 2 0 0 2 2 2 0 Putative metallopeptidase domain Septin PF00735.13 EPS34223.1 - 2e-123 410.8 0.1 2e-123 410.8 0.1 1.8 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EPS34223.1 - 2.1e-07 30.9 0.0 4e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EPS34223.1 - 5.2e-05 22.4 0.2 0.00022 20.4 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EPS34223.1 - 0.00011 21.6 2.3 0.0013 18.2 0.0 3.0 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EPS34223.1 - 0.00023 21.4 2.5 0.033 14.4 0.0 2.8 3 0 0 3 3 3 1 ABC transporter AAA_10 PF12846.2 EPS34223.1 - 0.00037 20.0 0.2 0.0023 17.4 0.0 2.1 2 0 0 2 2 2 1 AAA-like domain AIG1 PF04548.11 EPS34223.1 - 0.00086 18.4 0.0 0.00086 18.4 0.0 2.1 2 0 0 2 2 2 1 AIG1 family AAA_16 PF13191.1 EPS34223.1 - 0.0033 17.4 0.2 0.017 15.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EPS34223.1 - 0.0041 17.2 0.0 0.016 15.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain Ras PF00071.17 EPS34223.1 - 0.005 16.2 0.0 0.016 14.6 0.0 1.9 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPS34223.1 - 0.0083 16.6 0.2 0.033 14.6 0.0 2.1 2 0 0 2 2 1 1 Miro-like protein AAA_29 PF13555.1 EPS34223.1 - 0.0091 15.5 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EPS34223.1 - 0.01 15.3 0.7 0.025 14.0 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family Exonuc_VII_L PF02601.10 EPS34223.1 - 0.015 14.4 5.5 0.031 13.4 3.8 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Dynamin_N PF00350.18 EPS34223.1 - 0.034 13.9 6.0 0.37 10.6 0.1 3.5 2 1 0 3 3 3 0 Dynamin family ATP_bind_1 PF03029.12 EPS34223.1 - 0.047 13.2 0.4 5.2 6.5 0.0 2.9 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 EPS34223.1 - 0.11 12.0 0.6 0.21 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EPS34223.1 - 0.12 12.0 0.1 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EPS34223.1 - 0.14 12.3 0.5 0.83 9.8 0.0 2.3 2 0 0 2 2 2 0 RNA helicase Phage_GPO PF05929.6 EPS34223.1 - 0.18 11.0 7.0 0.29 10.3 4.8 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase AAA_32 PF13654.1 EPS34223.1 - 0.19 10.3 11.3 0.49 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain YlqD PF11068.3 EPS34223.1 - 0.21 11.6 10.7 0.4 10.7 7.4 1.5 1 0 0 1 1 1 0 YlqD protein DUF87 PF01935.12 EPS34223.1 - 0.57 9.9 3.3 3.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 DUF2937 PF11157.3 EPS34223.1 - 0.63 9.3 3.0 1.4 8.2 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) IncA PF04156.9 EPS34223.1 - 2.5 7.6 8.8 4.3 6.8 6.1 1.4 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 EPS34223.1 - 6.3 4.5 9.6 9.2 3.9 6.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Aminotran_1_2 PF00155.16 EPS34224.1 - 2.3e-22 79.4 0.0 2.9e-22 79.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EPS34224.1 - 0.013 14.0 0.0 0.22 10.0 0.0 2.1 2 0 0 2 2 2 0 Alanine-glyoxylate amino-transferase Aminotran_1_2 PF00155.16 EPS34225.1 - 6.5e-44 150.3 0.0 8.4e-44 149.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EPS34225.1 - 2.3e-08 33.2 0.0 1e-07 31.0 0.0 1.8 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EPS34225.1 - 1.7e-07 30.6 0.0 2.7e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EPS34225.1 - 1.3e-06 27.0 0.0 1.8e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EPS34225.1 - 6.9e-06 25.3 0.0 9.3e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Fungal_trans_2 PF11951.3 EPS34226.1 - 5e-54 183.3 3.4 5.6e-54 183.2 2.4 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3328 PF11807.3 EPS34228.1 - 2.9e-33 115.4 3.7 3.7e-33 115.0 2.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) PDR_assoc PF08370.6 EPS34228.1 - 0.084 12.3 0.1 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Plant PDR ABC transporter associated EamA PF00892.15 EPS34229.1 - 5e-11 42.7 21.8 2.1e-06 27.7 5.7 2.8 2 1 1 3 3 3 2 EamA-like transporter family FAD_binding_3 PF01494.14 EPS34230.1 - 1.1e-11 44.3 0.0 0.0041 16.2 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 EPS34230.1 - 0.0087 16.0 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EPS34230.1 - 0.055 13.5 0.0 0.18 11.8 0.0 1.9 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EPS34230.1 - 0.08 13.3 0.0 0.25 11.7 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PBP PF01161.15 EPS34230.1 - 0.086 12.6 0.0 3.8 7.3 0.0 2.5 2 1 1 3 3 3 0 Phosphatidylethanolamine-binding protein Sdh_cyt PF01127.17 EPS34231.1 - 2.2e-16 59.7 4.2 2.9e-16 59.3 2.9 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Methyltransf_2 PF00891.13 EPS34232.1 - 5.4e-31 107.6 0.0 1e-30 106.7 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Dimerisation PF08100.6 EPS34232.1 - 0.0011 18.7 1.7 0.016 15.0 0.2 2.6 2 0 0 2 2 2 1 Dimerisation domain AraC_N PF06719.8 EPS34232.1 - 0.0071 15.6 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 AraC-type transcriptional regulator N-terminus Methyltransf_23 PF13489.1 EPS34232.1 - 0.013 15.2 0.0 0.029 14.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_19 PF04672.7 EPS34232.1 - 0.022 14.0 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl methyltransferase Fungal_trans PF04082.13 EPS34233.1 - 1.3e-18 66.8 0.6 2.2e-18 66.1 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS34233.1 - 1.4e-08 34.4 4.6 2.6e-08 33.6 3.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMP-binding PF00501.23 EPS34234.1 - 6.1e-87 291.7 0.1 1.6e-86 290.3 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EPS34234.1 - 7.5e-69 232.0 0.0 1.4e-68 231.1 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EPS34234.1 - 2.2e-56 190.3 0.0 1.4e-55 187.8 0.0 2.4 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 EPS34234.1 - 2.4e-53 181.5 0.1 4.3e-53 180.7 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EPS34234.1 - 2.6e-52 177.8 0.0 4.2e-52 177.1 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EPS34234.1 - 1.1e-46 158.8 0.0 8.2e-46 155.9 0.0 2.7 2 0 0 2 2 2 1 short chain dehydrogenase Condensation PF00668.15 EPS34234.1 - 5.8e-44 150.1 0.6 1e-43 149.3 0.4 1.3 1 0 0 1 1 1 1 Condensation domain Ketoacyl-synt_C PF02801.17 EPS34234.1 - 3.6e-33 113.9 0.0 8.1e-33 112.8 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 EPS34234.1 - 1.2e-22 80.1 0.0 2.2e-21 75.9 0.0 2.5 1 1 0 1 1 1 1 Male sterility protein Methyltransf_12 PF08242.7 EPS34234.1 - 6.5e-19 68.2 0.0 2.6e-18 66.3 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EPS34234.1 - 1.8e-17 63.3 0.0 4.4e-09 36.4 0.0 3.0 3 0 0 3 3 2 2 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 EPS34234.1 - 4.2e-15 55.8 0.0 1.3e-14 54.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPS34234.1 - 2.3e-11 44.0 0.0 9e-11 42.1 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPS34234.1 - 1.7e-10 40.6 0.0 5.4e-09 35.8 0.0 3.0 3 0 0 3 3 2 1 Methyltransferase domain HxxPF_rpt PF13745.1 EPS34234.1 - 3.7e-10 39.9 0.1 1.3e-09 38.2 0.0 2.0 2 0 0 2 2 1 1 HxxPF-repeated domain Methyltransf_18 PF12847.2 EPS34234.1 - 4.5e-10 40.0 0.0 3e-09 37.4 0.0 2.6 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 EPS34234.1 - 3.3e-09 36.5 0.0 0.00014 21.3 0.0 2.5 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Ubie_methyltran PF01209.13 EPS34234.1 - 6.6e-07 28.6 0.0 9e-06 24.9 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.18 EPS34234.1 - 0.00084 18.3 0.0 0.0016 17.4 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_16 PF10294.4 EPS34234.1 - 0.0013 18.2 0.0 0.0028 17.1 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase RrnaAD PF00398.15 EPS34234.1 - 0.0015 17.6 0.0 0.0053 15.8 0.0 1.9 2 0 0 2 2 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.9 EPS34234.1 - 0.15 11.4 0.0 0.47 9.8 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase small domain C9orf72-like PF15019.1 EPS34234.1 - 0.3 10.3 1.0 0.43 9.7 0.1 1.6 2 0 0 2 2 2 0 C9orf72-like protein family Asp23 PF03780.8 EPS34234.1 - 0.54 10.5 0.0 1.2 9.4 0.0 1.6 1 0 0 1 1 1 0 Asp23 family Polysacc_synt_2 PF02719.10 EPS34234.1 - 1.2 7.9 0.0 2.1 7.1 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein AATase PF07247.7 EPS34234.1 - 4.3 5.7 0.2 16 3.8 0.0 2.0 2 0 0 2 2 2 0 Alcohol acetyltransferase p450 PF00067.17 EPS34235.1 - 2.8e-45 154.6 0.0 3.5e-45 154.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 EPS34236.1 - 1.6e-63 214.9 0.0 2.2e-63 214.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EPS34236.1 - 3.8e-05 22.7 0.3 0.00032 19.7 0.3 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EPS34236.1 - 0.00036 19.7 0.0 0.00099 18.2 0.0 1.7 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EPS34236.1 - 0.00052 19.9 0.0 0.0013 18.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPS34236.1 - 0.00056 19.8 0.2 0.0018 18.2 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EPS34236.1 - 0.0016 18.8 0.0 0.0036 17.6 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EPS34236.1 - 0.0044 15.5 1.2 0.0088 14.5 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 EPS34236.1 - 0.013 15.5 0.0 0.045 13.8 0.0 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EPS34236.1 - 0.019 15.1 0.0 0.058 13.6 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding Trp_halogenase PF04820.9 EPS34236.1 - 0.026 13.1 0.2 0.12 10.9 0.2 1.9 1 1 0 2 2 2 0 Tryptophan halogenase FAD_binding_2 PF00890.19 EPS34236.1 - 0.031 13.1 0.2 0.12 11.2 0.0 2.0 3 0 0 3 3 3 0 FAD binding domain AlaDh_PNT_C PF01262.16 EPS34236.1 - 0.08 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.16 EPS34236.1 - 0.13 12.1 0.3 0.27 11.0 0.2 1.4 1 0 0 1 1 1 0 ThiF family ADH_zinc_N PF00107.21 EPS34237.1 - 1.4e-06 27.8 0.0 3e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EPS34237.1 - 1.1e-05 25.1 0.0 0.00031 20.4 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain p450 PF00067.17 EPS34238.1 - 2.9e-26 92.0 0.0 5e-25 87.9 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 NADH_oxidored PF08040.6 EPS34238.1 - 0.05 13.2 0.1 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 MNLL subunit Hexapep_2 PF14602.1 EPS34239.1 - 2.3e-17 62.2 7.1 5.5e-12 45.0 0.7 3.0 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 EPS34239.1 - 1.1e-16 60.6 0.1 1.6e-16 60.0 0.1 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.19 EPS34239.1 - 1.7e-14 52.5 11.5 3.4e-12 45.2 1.1 4.0 4 0 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) F-box PF00646.28 EPS34240.1 - 5.3e-06 25.9 0.1 1.3e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EPS34240.1 - 0.00053 19.6 0.0 0.0013 18.3 0.0 1.7 1 0 0 1 1 1 1 F-box-like zf-P11 PF03854.9 EPS34240.1 - 7.8 6.0 7.2 0.28 10.6 0.2 2.2 3 0 0 3 3 3 0 P-11 zinc finger Mito_carr PF00153.22 EPS34241.1 - 1.7e-60 200.7 4.0 5e-20 71.0 0.0 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF605 PF04652.11 EPS34241.1 - 5.4 6.3 7.1 9.1 5.5 4.9 1.3 1 0 0 1 1 1 0 Vta1 like TPK_catalytic PF04263.11 EPS34243.1 - 7.3e-23 80.4 0.1 9.7e-17 60.7 0.0 2.2 2 0 0 2 2 2 2 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 EPS34243.1 - 8.9e-20 70.1 0.1 1.5e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain DUF725 PF05267.7 EPS34243.1 - 0.069 13.0 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF725) CHCH PF06747.8 EPS34244.1 - 1.2e-07 31.4 4.4 2e-07 30.7 3.1 1.4 1 0 0 1 1 1 1 CHCH domain GCK PF07802.6 EPS34244.1 - 0.027 14.6 1.9 0.05 13.7 1.3 1.4 1 0 0 1 1 1 0 GCK domain Ribosomal_S4 PF00163.14 EPS34246.1 - 5.2e-24 84.4 0.9 8.7e-24 83.7 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EPS34246.1 - 6.8e-14 51.0 1.1 6.8e-14 51.0 0.8 3.0 3 0 0 3 3 3 1 S4 domain MARVEL PF01284.18 EPS34247.1 - 0.48 10.2 12.3 0.94 9.2 8.5 1.5 1 1 0 1 1 1 0 Membrane-associating domain DUF1434 PF07254.7 EPS34247.1 - 2.3 8.0 6.6 0.42 10.4 1.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1434) FAD_binding_4 PF01565.18 EPS34248.1 - 2.3e-18 65.9 2.4 5.3e-18 64.8 1.7 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EPS34248.1 - 6.4e-08 32.3 0.2 1.5e-07 31.2 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like Mito_carr PF00153.22 EPS34249.1 - 0.011 15.3 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial carrier protein Upf2 PF04050.9 EPS34250.1 - 1.1e-60 204.2 18.5 1.1e-60 204.2 12.8 2.7 3 0 0 3 3 3 1 Up-frameshift suppressor 2 MIF4G PF02854.14 EPS34250.1 - 4.5e-59 199.3 0.1 1.6e-31 109.3 0.0 3.5 4 0 0 4 4 4 3 MIF4G domain DUF2383 PF09537.5 EPS34251.1 - 0.1 12.8 0.1 0.14 12.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) SUN PF03856.8 EPS34254.1 - 3.4e-96 321.3 11.2 4.8e-96 320.8 7.8 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) APH PF01636.18 EPS34256.1 - 2.1e-09 37.4 0.0 4.1e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Herpes_UL36 PF03586.8 EPS34256.1 - 0.083 11.9 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL36 tegument protein Ribosomal_L29 PF00831.18 EPS34256.1 - 0.3 10.8 0.2 0.3 10.8 0.1 1.8 2 0 0 2 2 2 0 Ribosomal L29 protein Ribosomal_L1 PF00687.16 EPS34257.1 - 5.9e-55 185.9 3.3 5.9e-55 185.9 2.3 1.7 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family DUF799 PF05643.6 EPS34257.1 - 0.064 12.5 0.1 0.12 11.6 0.1 1.4 1 0 0 1 1 1 0 Putative bacterial lipoprotein (DUF799) DUF463 PF04317.7 EPS34257.1 - 0.1 11.1 1.2 0.32 9.4 0.0 2.0 2 0 0 2 2 2 0 YcjX-like family, DUF463 ETF PF01012.16 EPS34258.1 - 8.3e-41 139.4 1.1 1.2e-40 138.8 0.2 1.6 2 0 0 2 2 2 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 EPS34258.1 - 1.9e-34 117.1 0.1 3.8e-34 116.1 0.1 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Aldo_ket_red PF00248.16 EPS34259.1 - 2.5e-60 203.7 0.0 3e-60 203.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ATP_bind_4 PF01902.12 EPS34259.1 - 0.061 12.6 0.1 0.51 9.6 0.0 2.2 2 1 0 2 2 2 0 ATP-binding region DUF1542 PF07564.6 EPS34259.1 - 0.18 11.8 0.9 1 9.4 0.0 2.5 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1542) AAA PF00004.24 EPS34260.1 - 1.8e-11 44.3 0.0 5.2e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPS34260.1 - 3.2e-06 27.2 0.0 7.8e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EPS34260.1 - 3.5e-05 22.9 0.0 8.3e-05 21.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EPS34260.1 - 0.00013 21.7 0.0 0.00025 20.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Rad17 PF03215.10 EPS34260.1 - 0.00021 20.1 0.0 0.00047 18.9 0.0 1.5 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_33 PF13671.1 EPS34260.1 - 0.00032 20.5 0.0 0.00086 19.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPS34260.1 - 0.00035 21.3 0.0 0.0015 19.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EPS34260.1 - 0.00039 20.1 0.0 0.0012 18.5 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EPS34260.1 - 0.0028 17.6 0.4 0.023 14.7 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EPS34260.1 - 0.0036 17.1 0.0 0.0066 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EPS34260.1 - 0.0043 16.1 0.0 0.012 14.7 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.16 EPS34260.1 - 0.039 13.1 0.1 1.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EPS34260.1 - 0.043 14.1 0.0 0.18 12.0 0.0 2.2 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EPS34260.1 - 0.055 12.6 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 TIP49 PF06068.8 EPS34260.1 - 0.057 12.1 0.0 0.097 11.3 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus IstB_IS21 PF01695.12 EPS34260.1 - 0.1 12.0 0.1 0.38 10.1 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein SR-25 PF10500.4 EPS34261.1 - 3.2 7.1 8.8 3.8 6.9 6.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cellulase PF00150.13 EPS34262.1 - 2.7e-57 194.1 2.0 3.6e-57 193.7 1.4 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 EPS34262.1 - 3.3e-14 52.2 9.6 3.3e-14 52.2 6.6 2.6 2 0 0 2 2 2 1 Fungal cellulose binding domain Fungal_trans PF04082.13 EPS34263.1 - 3.3e-14 52.3 1.0 4.8e-14 51.8 0.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EPS34264.1 - 1.8e-41 142.0 44.3 1.8e-41 142.0 30.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily MIF4G_like PF09088.6 EPS34264.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 MIF4G like LMF1 PF06762.9 EPS34264.1 - 0.26 10.0 2.2 0.49 9.1 1.5 1.3 1 0 0 1 1 1 0 Lipase maturation factor FAD_binding_3 PF01494.14 EPS34265.1 - 3.6e-13 49.3 0.4 6.1e-12 45.2 0.3 2.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EPS34265.1 - 6.8e-10 38.3 1.1 0.0011 17.9 0.0 3.0 2 1 1 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.9 EPS34265.1 - 0.00025 19.6 0.0 0.0048 15.4 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 EPS34265.1 - 0.0012 17.7 0.1 0.0021 16.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EPS34265.1 - 0.0031 17.6 0.1 0.046 13.7 0.1 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPS34265.1 - 0.011 15.6 0.3 0.021 14.7 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPS34265.1 - 0.018 15.0 0.0 0.047 13.7 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EPS34265.1 - 0.021 13.9 0.1 0.039 13.0 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.12 EPS34265.1 - 0.028 13.5 0.1 0.1 11.7 0.0 1.8 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.7 EPS34265.1 - 0.049 12.5 0.0 0.088 11.7 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein p450 PF00067.17 EPS34266.1 - 9e-32 110.1 0.0 1.4e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 EPS34267.1 - 9.2e-15 54.9 0.0 1.4e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EPS34267.1 - 3.1e-08 33.3 0.0 1.3e-07 31.3 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EPS34267.1 - 2.1e-06 27.5 0.0 3.6e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EPS34267.1 - 2.7e-06 27.3 0.0 3.4e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EPS34267.1 - 0.063 13.2 0.1 0.16 11.9 0.1 1.7 1 1 0 1 1 1 0 NADH(P)-binding EthD PF07110.6 EPS34268.1 - 7.2e-21 74.9 0.3 8.9e-21 74.6 0.2 1.1 1 0 0 1 1 1 1 EthD domain DUF4243 PF14027.1 EPS34269.1 - 2.9e-91 306.3 1.1 3.5e-91 306.0 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) NAD_binding_10 PF13460.1 EPS34270.1 - 2.6e-12 47.1 0.0 3.6e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EPS34270.1 - 7.1e-08 31.9 0.0 1.1e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 EPS34270.1 - 0.00071 18.3 0.1 0.00098 17.8 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EPS34270.1 - 0.013 14.9 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EPS34270.1 - 0.035 14.4 0.0 0.062 13.5 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 EPS34270.1 - 0.041 12.8 0.0 0.11 11.3 0.0 1.7 2 0 0 2 2 2 0 Male sterility protein DUF943 PF06092.7 EPS34270.1 - 0.072 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Enterobacterial putative membrane protein (DUF943) Polysacc_synt_2 PF02719.10 EPS34270.1 - 0.082 11.7 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein HSP20 PF00011.16 EPS34271.1 - 0.00012 21.8 0.5 0.049 13.5 0.0 2.2 1 1 1 2 2 2 2 Hsp20/alpha crystallin family Scytalone_dh PF02982.9 EPS34272.1 - 3.8e-71 237.8 0.2 4.3e-71 237.6 0.2 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 EPS34272.1 - 0.00011 22.0 0.8 0.00016 21.5 0.5 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF3105 PF11303.3 EPS34272.1 - 0.14 11.9 0.7 4.3 7.1 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3105) ketoacyl-synt PF00109.21 EPS34273.1 - 4.3e-70 236.0 0.2 7.4e-70 235.3 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EPS34273.1 - 1.1e-49 169.5 0.0 9.4e-49 166.4 0.0 2.3 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EPS34273.1 - 9e-33 112.6 1.3 2e-32 111.5 0.9 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EPS34273.1 - 5.9e-11 42.4 1.3 1.3e-10 41.3 0.2 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site PS-DH PF14765.1 EPS34273.1 - 1.6e-09 37.3 0.0 3.5e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.18 EPS34273.1 - 0.00026 20.0 0.2 0.00057 18.9 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Lactamase_B PF00753.22 EPS34274.1 - 2.2e-24 86.1 2.2 2.2e-24 86.1 0.9 1.4 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EPS34274.1 - 1.3e-05 24.8 0.7 3.4e-05 23.4 0.5 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain adh_short PF00106.20 EPS34275.1 - 5e-32 111.1 0.6 6.6e-32 110.7 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPS34275.1 - 1.1e-30 107.2 0.2 1.3e-30 106.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPS34275.1 - 7.6e-17 61.5 0.6 1.1e-16 61.0 0.4 1.1 1 0 0 1 1 1 1 KR domain DUF460 PF04312.8 EPS34275.1 - 0.0045 16.5 0.1 0.012 15.1 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF460) DUF1776 PF08643.5 EPS34275.1 - 0.0075 15.4 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EPS34275.1 - 0.0091 15.4 0.3 0.028 13.8 0.2 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EPS34275.1 - 0.052 12.6 0.2 0.18 10.8 0.0 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain F420_oxidored PF03807.12 EPS34275.1 - 0.098 13.0 0.4 0.26 11.7 0.1 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Eno-Rase_NADH_b PF12242.3 EPS34275.1 - 0.11 12.2 0.3 0.24 11.1 0.2 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase SnoaL_2 PF12680.2 EPS34276.1 - 0.00021 21.6 0.0 0.00027 21.2 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain Methyltransf_11 PF08241.7 EPS34278.1 - 8.3e-14 51.8 0.0 1.5e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPS34278.1 - 1.8e-10 40.6 0.0 2.6e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPS34278.1 - 3.9e-08 33.1 0.0 5.7e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPS34278.1 - 6e-07 29.8 0.0 9.7e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS34278.1 - 1.8e-06 28.4 0.0 3e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EPS34278.1 - 0.00011 22.4 0.0 0.00022 21.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 EPS34278.1 - 0.00097 18.0 0.0 0.0014 17.5 0.0 1.1 1 0 0 1 1 1 1 DREV methyltransferase Ubie_methyltran PF01209.13 EPS34278.1 - 0.025 13.7 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EPS34278.1 - 0.034 14.1 0.1 0.092 12.7 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EPS34278.1 - 0.035 13.4 0.0 0.057 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain AflR PF08493.5 EPS34279.1 - 9.8e-23 80.5 6.7 1.5e-22 79.9 4.6 1.2 1 0 0 1 1 1 1 Aflatoxin regulatory protein Zn_clus PF00172.13 EPS34279.1 - 7.1e-06 25.8 10.6 2e-05 24.4 7.4 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cut8_M PF14483.1 EPS34281.1 - 0.00047 19.8 0.2 0.00094 18.9 0.1 1.5 1 0 0 1 1 1 1 Cut8 dimerisation domain H_lectin PF09458.5 EPS34283.1 - 0.0078 15.8 0.0 0.061 12.9 0.0 2.2 2 0 0 2 2 2 1 H-type lectin domain Nepo_coat_N PF03689.10 EPS34283.1 - 0.022 14.4 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Nepovirus coat protein, N-terminal domain SKG6 PF08693.5 EPS34284.1 - 6.2e-06 25.4 0.2 6.2e-06 25.4 0.1 2.3 3 0 0 3 3 3 1 Transmembrane alpha-helix domain Keratin_B2 PF01500.12 EPS34284.1 - 0.011 15.4 1.6 0.018 14.8 1.1 1.3 1 0 0 1 1 1 0 Keratin, high sulfur B2 protein Marek_A PF02124.10 EPS34284.1 - 0.054 12.9 0.1 0.072 12.5 0.1 1.1 1 0 0 1 1 1 0 Marek's disease glycoprotein A DUF347 PF03988.7 EPS34284.1 - 0.27 11.1 5.9 0.9 9.4 0.3 2.4 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) Glyco_hydro_47 PF01532.15 EPS34285.1 - 6.4e-163 542.6 0.0 7.3e-163 542.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF4038 PF13204.1 EPS34285.1 - 0.044 13.0 0.0 0.1 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) Glyco_transf_8 PF01501.15 EPS34287.1 - 0.00015 21.2 1.4 0.00055 19.3 1.0 2.0 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EPS34287.1 - 0.0063 15.9 0.0 0.0099 15.2 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative GST_N PF02798.15 EPS34289.1 - 3.2e-13 49.6 0.0 7e-13 48.5 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EPS34289.1 - 3e-12 46.6 0.0 5.1e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EPS34289.1 - 6e-12 45.3 0.0 1.1e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EPS34289.1 - 2.9e-10 39.9 0.0 4.8e-10 39.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EPS34289.1 - 7.8e-08 32.0 0.1 1.5e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EPS34289.1 - 2.8e-05 24.4 0.2 4.5e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 EPS34289.1 - 0.08 13.3 0.0 0.18 12.2 0.0 1.5 2 0 0 2 2 2 0 MetRS-N binding domain SWIRM PF04433.12 EPS34290.1 - 3.3e-34 116.8 0.1 8.7e-34 115.5 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 EPS34290.1 - 1.4e-06 28.2 0.0 2.8e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EPS34290.1 - 7.5e-06 25.9 0.1 1.8e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF896 PF05979.7 EPS34290.1 - 0.021 14.4 2.4 0.4 10.3 0.0 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF896) ZZ PF00569.12 EPS34290.1 - 0.044 13.3 4.3 0.24 10.9 3.0 2.0 1 1 0 1 1 1 0 Zinc finger, ZZ type V_ATPase_I PF01496.14 EPS34290.1 - 0.35 8.6 1.6 0.48 8.2 1.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Myb_DNA-binding PF00249.26 EPS34291.1 - 0.028 14.4 0.0 0.086 12.9 0.0 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain ResIII PF04851.10 EPS34292.1 - 9.9e-24 84.1 0.0 3e-23 82.6 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EPS34292.1 - 9.8e-14 50.9 0.2 2.8e-13 49.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EPS34292.1 - 3.3e-09 36.4 0.0 6e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.4 EPS34292.1 - 0.0028 16.6 0.0 0.0051 15.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) SNF2_N PF00176.18 EPS34292.1 - 0.1 11.3 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain ECM11 PF15463.1 EPS34292.1 - 4 7.7 7.5 0.37 11.0 0.7 2.3 2 0 0 2 2 2 0 Extracellular mutant protein 11 ABC_tran PF00005.22 EPS34293.1 - 4.3e-47 159.8 0.1 2.9e-24 85.9 0.0 3.7 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EPS34293.1 - 5.9e-16 59.2 0.8 0.0019 18.2 0.1 4.3 3 1 1 4 4 4 3 AAA domain SMC_N PF02463.14 EPS34293.1 - 1.1e-13 50.9 0.0 3.3e-05 23.2 0.0 3.8 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EPS34293.1 - 1.4e-09 38.6 0.9 0.00045 20.5 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 EPS34293.1 - 3.3e-09 36.1 0.0 0.0016 17.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EPS34293.1 - 7e-08 33.3 0.0 0.0084 16.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EPS34293.1 - 6.5e-07 29.4 0.0 0.032 14.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EPS34293.1 - 1.3e-06 28.5 0.0 0.012 15.7 0.0 3.4 4 0 0 4 4 2 2 AAA domain PduV-EutP PF10662.4 EPS34293.1 - 1.8e-06 27.4 0.0 0.085 12.3 0.0 2.9 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 EPS34293.1 - 3.2e-06 26.4 0.0 0.002 17.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA PF00004.24 EPS34293.1 - 4.9e-06 26.7 0.0 0.19 11.9 0.0 4.4 4 1 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) HEAT_2 PF13646.1 EPS34293.1 - 6.1e-06 26.4 0.3 0.026 14.8 0.1 3.4 2 1 2 4 4 3 3 HEAT repeats AAA_16 PF13191.1 EPS34293.1 - 8.1e-06 25.9 0.0 0.41 10.5 0.0 3.6 4 0 0 4 4 3 2 AAA ATPase domain AAA_10 PF12846.2 EPS34293.1 - 1.2e-05 24.9 0.0 0.26 10.6 0.0 3.2 4 0 0 4 4 4 2 AAA-like domain SbcCD_C PF13558.1 EPS34293.1 - 1.3e-05 24.9 0.0 0.065 13.1 0.0 3.0 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 EPS34293.1 - 1.3e-05 24.4 0.7 0.71 8.8 0.0 4.2 4 1 0 4 4 4 2 AAA ATPase domain AAA_18 PF13238.1 EPS34293.1 - 2e-05 24.8 0.2 0.26 11.5 0.0 3.2 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 EPS34293.1 - 2.5e-05 24.1 0.0 0.018 14.9 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_13 PF13166.1 EPS34293.1 - 3.4e-05 22.5 0.0 0.52 8.6 0.0 3.6 4 0 0 4 4 4 2 AAA domain NACHT PF05729.7 EPS34293.1 - 5.2e-05 22.9 0.0 0.054 13.1 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_14 PF13173.1 EPS34293.1 - 7.5e-05 22.6 0.0 0.4 10.5 0.0 3.6 4 0 0 4 4 2 1 AAA domain Miro PF08477.8 EPS34293.1 - 9.8e-05 22.8 0.0 0.064 13.7 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein RNA_helicase PF00910.17 EPS34293.1 - 0.0001 22.4 0.0 0.68 10.1 0.0 2.8 2 0 0 2 2 2 2 RNA helicase MobB PF03205.9 EPS34293.1 - 0.00011 21.9 0.2 0.78 9.4 0.0 3.2 3 0 0 3 3 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EPS34293.1 - 0.00019 21.3 0.0 0.65 9.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EPS34293.1 - 0.00024 20.8 0.0 0.12 12.0 0.0 2.8 2 0 0 2 2 2 1 Archaeal ATPase DUF87 PF01935.12 EPS34293.1 - 0.00029 20.7 0.1 0.16 11.7 0.0 2.9 3 0 0 3 3 2 1 Domain of unknown function DUF87 Dynamin_N PF00350.18 EPS34293.1 - 0.00066 19.5 0.0 0.0055 16.5 0.0 2.4 2 0 0 2 2 2 1 Dynamin family cobW PF02492.14 EPS34293.1 - 0.0012 18.3 1.1 0.58 9.5 0.0 3.3 4 0 0 4 4 4 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 EPS34293.1 - 0.0013 17.5 0.1 0.65 8.7 0.0 2.4 2 0 0 2 2 2 1 ArgK protein HEAT PF02985.17 EPS34293.1 - 0.0013 18.6 0.7 7.5 6.9 0.0 5.3 5 0 0 5 5 5 0 HEAT repeat AAA_30 PF13604.1 EPS34293.1 - 0.0014 18.2 0.0 2.1 7.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 EPS34293.1 - 0.0016 17.8 0.0 2.2 7.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EPS34293.1 - 0.0022 17.7 0.1 4.9 6.9 0.0 3.2 3 0 0 3 3 3 0 Part of AAA domain HEAT_EZ PF13513.1 EPS34293.1 - 0.0027 18.1 6.7 5.7 7.5 0.0 5.3 5 1 1 6 6 4 0 HEAT-like repeat ATP-synt_ab PF00006.20 EPS34293.1 - 0.0027 17.2 0.0 0.7 9.3 0.0 2.5 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 EPS34293.1 - 0.0029 17.0 0.5 1.1 8.6 0.0 3.4 3 0 0 3 3 3 1 FtsK/SpoIIIE family ATP_bind_1 PF03029.12 EPS34293.1 - 0.0067 16.0 0.0 4.3 6.8 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein T2SE PF00437.15 EPS34293.1 - 0.012 14.5 0.0 3 6.6 0.0 2.6 2 0 0 2 2 2 0 Type II/IV secretion system protein NB-ARC PF00931.17 EPS34293.1 - 0.025 13.4 0.0 0.27 10.0 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain UPF0079 PF02367.12 EPS34293.1 - 0.027 14.1 0.0 4.2 7.0 0.0 3.2 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 AAA_5 PF07728.9 EPS34293.1 - 0.028 14.1 0.0 13 5.4 0.0 3.5 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) Septin PF00735.13 EPS34293.1 - 0.037 13.0 0.0 2 7.3 0.0 2.5 2 0 0 2 2 2 0 Septin Mg_chelatase PF01078.16 EPS34293.1 - 0.041 13.0 0.0 3.5 6.7 0.0 2.8 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI ParcG PF10274.4 EPS34293.1 - 0.09 12.6 0.2 3.4 7.5 0.0 2.9 1 1 2 3 3 3 0 Parkin co-regulated protein DUF1542 PF07564.6 EPS34293.1 - 0.32 11.0 7.2 1.4 8.9 0.8 3.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) DUF4591 PF15261.1 EPS34295.1 - 0.32 11.2 5.5 0.36 11.0 3.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4591) PGAP1 PF07819.8 EPS34296.1 - 2.7e-84 282.2 0.0 4.7e-84 281.4 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EPS34296.1 - 1.8e-08 34.2 0.1 3.5e-08 33.3 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPS34296.1 - 3.2e-06 27.1 0.1 6.1e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPS34296.1 - 0.0009 18.8 0.0 0.0019 17.7 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EPS34296.1 - 0.0038 16.6 0.0 0.032 13.6 0.0 2.0 2 0 0 2 2 2 1 Putative esterase LCAT PF02450.10 EPS34296.1 - 0.0054 15.7 0.0 0.0089 15.0 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF676 PF05057.9 EPS34296.1 - 0.037 13.3 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PaaX_C PF08223.6 EPS34296.1 - 0.11 12.1 0.3 0.42 10.2 0.0 2.0 2 0 0 2 2 2 0 PaaX-like protein C-terminal domain Sugar_tr PF00083.19 EPS34297.1 - 6.2e-33 114.0 23.9 1.5e-32 112.8 16.6 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS34297.1 - 1.1e-28 100.0 49.0 2.4e-27 95.5 21.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF533 PF04391.7 EPS34300.1 - 0.0032 16.8 4.9 0.0032 16.8 3.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF533) SR-25 PF10500.4 EPS34300.1 - 0.017 14.6 18.8 0.022 14.2 13.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Rick_17kDa_Anti PF05433.10 EPS34300.1 - 0.018 14.7 19.3 0.041 13.5 13.4 1.6 1 0 0 1 1 1 0 Glycine zipper 2TM domain DUF3824 PF12868.2 EPS34300.1 - 0.02 15.8 2.9 0.02 15.8 2.0 3.3 2 1 0 2 2 2 0 Domain of unknwon function (DUF3824) DUF755 PF05501.6 EPS34300.1 - 0.44 10.6 23.9 0.74 9.8 16.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Gly-zipper_OmpA PF13436.1 EPS34300.1 - 0.77 9.4 13.4 0.92 9.1 8.3 1.9 1 1 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain BLVR PF06375.6 EPS34300.1 - 3 7.6 11.9 4.8 6.9 8.3 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Complex1_LYR_1 PF13232.1 EPS34301.1 - 0.00037 20.6 2.1 0.00072 19.7 1.4 1.5 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EPS34301.1 - 0.00074 19.2 2.1 0.0016 18.1 1.5 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) VWA_CoxE PF05762.9 EPS34301.1 - 0.071 12.2 0.9 0.14 11.2 0.6 1.4 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Ank_4 PF13637.1 EPS34302.1 - 3.5e-14 52.8 1.4 2.1e-10 40.8 0.2 4.0 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EPS34302.1 - 4.1e-08 33.4 0.4 0.00019 21.7 0.1 3.3 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EPS34302.1 - 4.5e-07 29.9 2.2 8.5e-05 22.6 0.1 3.6 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPS34302.1 - 3.4e-05 23.6 0.7 0.02 15.0 0.1 4.4 5 0 0 5 5 5 1 Ankyrin repeat KilA-N PF04383.8 EPS34302.1 - 0.0037 16.8 0.3 0.028 14.0 0.2 2.4 1 1 0 1 1 1 1 KilA-N domain Perilipin PF03036.11 EPS34302.1 - 0.019 13.8 0.6 0.032 13.0 0.4 1.3 1 0 0 1 1 1 0 Perilipin family Ank PF00023.25 EPS34302.1 - 0.048 13.4 3.9 0.26 11.1 0.2 3.7 3 0 0 3 3 3 0 Ankyrin repeat Macoilin PF09726.4 EPS34302.1 - 1.8 6.7 13.7 8.2 4.5 9.5 1.9 1 1 0 1 1 1 0 Transmembrane protein Cellulase PF00150.13 EPS34303.1 - 4.1e-32 111.5 3.4 1.1e-31 110.1 1.0 2.0 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) DUF295 PF03478.13 EPS34303.1 - 0.12 11.7 0.1 0.95 8.8 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF295) INCENP_N PF12178.3 EPS34303.1 - 0.12 11.8 0.1 1.1 8.8 0.0 2.5 2 0 0 2 2 2 0 Chromosome passenger complex (CPC) protein INCENP N terminal TPR_11 PF13414.1 EPS34304.1 - 6.4e-07 28.9 4.8 4e-06 26.3 0.0 4.0 4 1 1 5 5 5 2 TPR repeat TPR_2 PF07719.12 EPS34304.1 - 8.1e-06 25.3 1.5 0.012 15.4 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EPS34304.1 - 4.4e-05 22.9 0.7 0.0084 15.6 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EPS34304.1 - 0.0034 17.0 0.1 1.4 8.8 0.0 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EPS34304.1 - 0.012 16.2 0.0 0.012 16.2 0.0 4.7 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 EPS34304.1 - 0.016 14.9 2.9 1.8 8.5 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EPS34304.1 - 0.027 15.0 0.0 0.027 15.0 0.0 6.0 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.1 EPS34304.1 - 0.059 13.5 0.0 1.9 8.9 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 EPS34304.1 - 0.29 11.5 3.9 1.2 9.5 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Methyltransf_10 PF05971.7 EPS34305.1 - 9.4e-66 221.9 0.0 1.3e-65 221.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_26 PF13659.1 EPS34305.1 - 8e-07 29.1 0.1 1.9e-06 27.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EPS34305.1 - 1.6e-06 27.6 0.0 3.1e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EPS34305.1 - 3.2e-06 27.7 0.0 9.9e-06 26.1 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain UPF0020 PF01170.13 EPS34305.1 - 0.00053 19.6 0.0 0.00095 18.7 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.1 EPS34305.1 - 0.00093 18.8 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPS34305.1 - 0.002 17.2 0.0 0.0035 16.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.8 EPS34305.1 - 0.0025 17.0 0.0 0.004 16.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 EPS34305.1 - 0.0053 17.2 0.0 0.011 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 EPS34305.1 - 0.023 13.7 0.0 0.04 12.9 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_25 PF13649.1 EPS34305.1 - 0.029 14.7 0.0 0.068 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF633 PF04816.7 EPS34305.1 - 0.077 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF633) ADC PF06314.6 EPS34305.1 - 0.12 11.6 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Acetoacetate decarboxylase (ADC) RnfC_N PF13375.1 EPS34305.1 - 0.13 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain adh_short PF00106.20 EPS34306.1 - 1.4e-29 103.1 1.9 1.8e-29 102.8 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPS34306.1 - 4.8e-23 82.1 0.0 5.7e-23 81.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPS34306.1 - 3.8e-15 56.0 1.0 5.4e-15 55.5 0.7 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPS34306.1 - 0.00063 19.2 0.1 0.0013 18.2 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EPS34306.1 - 0.001 17.8 0.0 0.0018 17.0 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family ACTH_domain PF00976.13 EPS34306.1 - 0.0065 16.2 0.0 0.18 11.6 0.0 2.4 2 0 0 2 2 2 1 Corticotropin ACTH domain zf-LITAF-like PF10601.4 EPS34307.1 - 2.2e-17 62.6 20.4 3.1e-17 62.1 14.1 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain JCAD PF15351.1 EPS34307.1 - 0.97 6.9 5.4 1.2 6.6 3.8 1.2 1 0 0 1 1 1 0 Junctional protein associated with coronary artery disease Elf1 PF05129.8 EPS34307.1 - 5.6 6.7 11.8 0.85 9.3 3.1 2.2 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like MFS_1 PF07690.11 EPS34308.1 - 2.9e-44 151.2 35.4 4.6e-39 134.1 17.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS34308.1 - 1.1e-10 40.6 11.7 1.1e-10 40.6 8.1 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_1_like PF12832.2 EPS34308.1 - 0.31 10.8 6.6 0.035 13.9 0.8 2.4 2 0 0 2 2 2 0 MFS_1 like family Na_H_Exchanger PF00999.16 EPS34309.1 - 7.7e-34 116.8 37.7 7.5e-26 90.5 19.1 3.0 3 0 0 3 3 3 3 Sodium/hydrogen exchanger family ADH_zinc_N PF00107.21 EPS34310.1 - 4.4e-09 35.9 0.1 7.3e-09 35.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPS34310.1 - 2.6e-05 25.1 0.1 4.5e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Acetyltransf_3 PF13302.1 EPS34311.1 - 9.4e-19 67.9 0.0 1.4e-18 67.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EPS34311.1 - 1.3e-12 47.5 0.0 2e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EPS34311.1 - 8.2e-06 25.7 0.0 1.3e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EPS34311.1 - 1.5e-05 24.9 0.0 2.4e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPS34311.1 - 0.002 17.8 0.0 0.0031 17.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EPS34311.1 - 0.11 12.6 0.0 0.23 11.5 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4602 PF15375.1 EPS34312.1 - 4.2e-06 26.8 12.1 4.2e-06 26.8 8.4 2.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4602) BSP_II PF05432.6 EPS34312.1 - 0.91 8.7 15.1 2 7.6 10.5 1.5 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) His_biosynth PF00977.16 EPS34313.1 - 9.9e-33 113.3 0.0 1.2e-32 113.0 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Esterase_phd PF10503.4 EPS34314.1 - 6.9e-24 84.3 1.0 1.1e-23 83.6 0.7 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.13 EPS34314.1 - 1.2e-13 50.4 13.7 7.9e-13 47.8 9.5 2.6 1 0 0 1 1 1 1 Fungal cellulose binding domain Peptidase_S9 PF00326.16 EPS34314.1 - 6.9e-13 48.3 1.7 1.4e-12 47.2 1.2 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EPS34314.1 - 2.3e-08 33.9 0.2 3.9e-08 33.1 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EPS34314.1 - 1.5e-05 24.5 1.3 1.5e-05 24.5 0.9 1.6 2 0 0 2 2 2 1 Putative esterase Abhydrolase_6 PF12697.2 EPS34314.1 - 8.4e-05 22.5 0.0 0.00012 22.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 EPS34314.1 - 0.00015 21.5 0.1 0.00025 20.8 0.1 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 EPS34314.1 - 0.001 18.7 0.1 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EPS34314.1 - 0.0012 18.4 0.4 0.0043 16.6 0.2 1.6 1 1 0 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.13 EPS34314.1 - 0.0072 15.6 0.5 0.013 14.8 0.3 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 EPS34314.1 - 0.0079 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase PAF-AH_p_II PF03403.8 EPS34314.1 - 0.15 10.3 0.1 0.25 9.6 0.1 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Toxin_7 PF05980.7 EPS34314.1 - 0.19 11.7 6.4 0.064 13.3 2.1 2.0 2 0 0 2 2 2 0 Toxin 7 Glyco_hydro_43 PF04616.9 EPS34315.1 - 3.6e-18 65.6 1.4 3.6e-18 65.6 1.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 Yip1 PF04893.12 EPS34316.1 - 0.0088 15.5 1.4 0.0099 15.3 1.0 1.1 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.7 EPS34316.1 - 0.012 15.2 0.7 0.013 15.1 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1282) MARVEL PF01284.18 EPS34316.1 - 0.025 14.3 1.5 0.032 14.0 1.0 1.2 1 0 0 1 1 1 0 Membrane-associating domain Radical_SAM PF04055.16 EPS34317.1 - 2.2e-17 63.7 0.0 6.2e-17 62.2 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 EPS34317.1 - 3.8e-12 46.0 0.1 9.8e-12 44.7 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EPS34317.1 - 0.039 14.0 0.1 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EPS34317.1 - 0.064 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein CoA_binding PF02629.14 EPS34318.1 - 9e-27 93.4 3.4 6.9e-26 90.5 0.6 2.3 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EPS34318.1 - 1.4e-22 79.9 0.1 2.4e-22 79.1 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EPS34318.1 - 4.5e-07 29.5 0.0 8.2e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EPS34318.1 - 0.003 17.7 0.1 0.012 15.8 0.1 2.0 2 0 0 2 2 2 1 CoA binding domain Isochorismatase PF00857.15 EPS34319.1 - 1.3e-17 64.3 0.0 1.5e-16 60.8 0.0 2.4 1 1 0 1 1 1 1 Isochorismatase family Big_2 PF02368.13 EPS34319.1 - 0.12 12.2 0.0 5.5 6.9 0.0 2.3 1 1 1 2 2 2 0 Bacterial Ig-like domain (group 2) DUF3446 PF11928.3 EPS34319.1 - 0.17 12.1 2.0 0.33 11.1 1.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) DUF3632 PF12311.3 EPS34320.1 - 8.6e-25 87.6 1.3 1.5e-24 86.8 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Glyco_hydro_28 PF00295.12 EPS34321.1 - 1.5e-48 165.4 7.4 2.4e-48 164.8 5.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 FA_desaturase PF00487.19 EPS34322.1 - 2.8e-15 56.4 22.7 2.8e-15 56.4 15.7 2.1 1 1 1 2 2 2 1 Fatty acid desaturase MFS_1 PF07690.11 EPS34323.1 - 8.7e-35 120.0 34.3 8.7e-35 120.0 23.8 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS34323.1 - 7.4e-16 57.7 21.4 1.2e-15 57.0 14.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter DUF455 PF04305.9 EPS34326.1 - 4.5e-102 340.6 0.0 6.1e-102 340.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.21 EPS34326.1 - 2.3e-06 27.1 0.0 4.6e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 EPS34326.1 - 4.7e-05 23.0 0.0 0.00011 21.8 0.0 1.7 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain MFS_1 PF07690.11 EPS34329.1 - 1.2e-34 119.6 30.4 1.7e-34 119.1 20.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF912 PF06024.7 EPS34329.1 - 0.028 14.4 0.0 2 8.4 0.0 3.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ESSS PF10183.4 EPS34329.1 - 0.23 11.8 3.7 0.12 12.7 0.3 2.3 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) RNA_pol_I_A49 PF06870.7 EPS34330.1 - 4.1e-53 180.3 0.0 7.4e-38 130.1 0.0 3.0 2 1 0 2 2 2 2 A49-like RNA polymerase I associated factor Aminotran_1_2 PF00155.16 EPS34331.1 - 2e-32 112.5 0.0 2.6e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EPS34331.1 - 6.4e-10 38.6 0.0 1.3e-09 37.6 0.0 1.5 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EPS34331.1 - 5.2e-09 35.3 0.0 8.1e-09 34.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EPS34331.1 - 6.9e-09 34.4 0.0 1e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.15 EPS34331.1 - 0.017 13.6 0.0 0.62 8.5 0.0 2.1 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, major domain Met_gamma_lyase PF06838.6 EPS34331.1 - 0.035 12.3 0.0 0.05 11.8 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase DegT_DnrJ_EryC1 PF01041.12 EPS34331.1 - 0.16 11.0 0.0 0.3 10.0 0.0 1.4 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EPS34332.1 - 1.2e-84 284.3 0.0 1.6e-84 283.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EPS34332.1 - 6e-06 24.7 0.0 1e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EPS34332.1 - 1.6e-05 23.8 0.0 3.2e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EPS34332.1 - 2.4e-05 23.5 0.6 5e-05 22.5 0.2 1.6 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 EPS34332.1 - 0.011 14.9 0.4 0.019 14.0 0.3 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase SNF2_N PF00176.18 EPS34333.1 - 6.9e-71 238.4 2.7 6.9e-71 238.4 1.9 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.1 EPS34333.1 - 4.7e-53 178.9 23.9 4.7e-53 178.9 16.6 3.5 4 0 0 4 4 4 1 DNA-binding domain Helicase_C PF00271.26 EPS34333.1 - 7.3e-17 61.0 0.0 2e-16 59.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ADH_N PF08240.7 EPS34335.1 - 2.5e-30 104.4 1.1 4.2e-30 103.7 0.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPS34335.1 - 1.4e-24 86.0 1.5 1.6e-24 85.9 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPS34335.1 - 0.00014 22.7 0.0 0.00028 21.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EPS34335.1 - 0.013 14.6 0.1 0.022 13.9 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EPS34335.1 - 0.072 12.6 0.2 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Glucokinase PF02685.11 EPS34335.1 - 0.12 11.0 1.6 0.2 10.3 0.9 1.4 1 1 0 1 1 1 0 Glucokinase Aminotran_3 PF00202.16 EPS34337.1 - 6.4e-104 347.4 0.0 7.6e-104 347.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Spt4 PF06093.8 EPS34338.1 - 7.8e-32 108.9 0.3 9.4e-32 108.7 0.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Metallophos PF00149.23 EPS34339.1 - 2.4e-36 125.0 0.0 3.7e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 EPS34339.1 - 1.8e-31 107.9 0.3 4.1e-31 106.8 0.2 1.6 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_11 PF13414.1 EPS34339.1 - 4.1e-18 64.7 7.0 5.6e-13 48.3 0.4 3.0 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 EPS34339.1 - 4.9e-08 32.2 4.1 0.015 14.9 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EPS34339.1 - 1.1e-06 28.1 4.7 0.38 10.7 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EPS34339.1 - 1.5e-06 28.7 2.9 0.046 14.4 0.3 3.0 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EPS34339.1 - 0.00014 22.1 1.1 0.052 13.8 0.0 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EPS34339.1 - 0.0047 16.7 0.1 0.31 10.9 0.1 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 EPS34339.1 - 0.027 14.8 1.1 0.96 10.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EPS34339.1 - 0.045 14.3 1.9 1.7 9.5 0.1 3.6 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.1 EPS34339.1 - 0.066 13.3 0.0 1.3 9.1 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 EPS34339.1 - 0.079 13.1 1.6 14 6.2 0.0 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF89 PF01937.14 EPS34340.1 - 1.1e-136 455.3 0.0 1.3e-136 455.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Cytochrom_C550 PF14495.1 EPS34340.1 - 0.0051 16.2 0.0 2.4 7.6 0.0 2.5 2 0 0 2 2 2 2 Cytochrome c-550 domain Cut12 PF11500.3 EPS34341.1 - 6.1e-46 155.8 7.7 6.1e-46 155.8 5.3 4.8 3 1 0 3 3 3 1 Spindle pole body formation-associated protein Seryl_tRNA_N PF02403.17 EPS34341.1 - 9.5 6.2 33.0 1.1 9.3 0.3 4.5 2 1 2 4 4 4 0 Seryl-tRNA synthetase N-terminal domain HGTP_anticodon2 PF12745.2 EPS34342.1 - 3.2e-83 279.0 3.0 3.2e-83 279.0 2.1 1.9 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs Pkinase PF00069.20 EPS34342.1 - 7.5e-67 225.2 0.0 1.1e-36 126.3 0.0 4.3 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EPS34342.1 - 6.6e-39 133.5 0.0 2.6e-17 62.7 0.0 3.5 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.17 EPS34342.1 - 3.7e-15 55.8 0.9 9.3e-15 54.5 0.1 2.1 2 0 0 2 2 2 1 RWD domain tRNA-synt_His PF13393.1 EPS34342.1 - 3.6e-13 49.2 0.7 2.3e-12 46.5 0.0 2.4 2 0 0 2 2 2 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.15 EPS34342.1 - 0.00039 20.3 0.3 0.0013 18.6 0.1 2.0 2 0 0 2 2 2 1 Anticodon binding domain APH PF01636.18 EPS34342.1 - 0.0013 18.5 0.0 0.0013 18.5 0.0 2.8 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EPS34342.1 - 0.0028 16.6 0.0 0.52 9.2 0.0 2.4 2 0 0 2 2 2 2 Kinase-like RRM_5 PF13893.1 EPS34343.1 - 7.2e-09 35.3 0.0 1.5e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPS34343.1 - 2.3e-08 33.5 0.0 4.6e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS34343.1 - 1.1e-06 28.5 0.0 2.1e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EPS34343.1 - 0.0019 17.9 0.0 0.0041 16.8 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 EPS34343.1 - 0.012 15.2 1.3 0.021 14.4 0.9 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MMR_HSR1 PF01926.18 EPS34344.1 - 4.8e-19 68.4 0.1 1.1e-18 67.2 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 EPS34344.1 - 2e-18 65.9 0.0 4.2e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 EPS34344.1 - 1.4e-12 47.2 0.0 2.3e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EPS34344.1 - 2.9e-05 23.9 0.3 0.031 14.0 0.0 2.5 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 EPS34344.1 - 0.00083 19.8 0.0 0.0022 18.4 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein ArgK PF03308.11 EPS34344.1 - 0.014 14.2 0.2 0.064 12.0 0.1 2.0 2 0 0 2 2 2 0 ArgK protein MCM PF00493.18 EPS34344.1 - 0.024 13.4 0.0 0.04 12.7 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family AIG1 PF04548.11 EPS34344.1 - 0.038 13.0 0.0 0.062 12.3 0.0 1.3 1 0 0 1 1 1 0 AIG1 family CPSase_sm_chain PF00988.17 EPS34345.1 - 8.2e-46 154.7 0.0 1.3e-45 154.0 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EPS34345.1 - 1.1e-45 155.5 0.0 1.5e-45 154.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EPS34345.1 - 2.7e-06 27.0 0.2 0.00011 21.7 0.1 2.3 1 1 0 1 1 1 1 Peptidase C26 Fungal_trans PF04082.13 EPS34346.1 - 2.1e-10 39.9 0.4 8.6e-10 37.9 0.0 1.9 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS34346.1 - 6.8e-09 35.5 9.3 1.1e-08 34.7 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PIG-X PF08320.7 EPS34347.1 - 5.2e-71 238.2 0.0 7e-71 237.7 0.0 1.2 1 0 0 1 1 1 1 PIG-X / PBN1 DUF3521 PF12035.3 EPS34347.1 - 0.021 14.6 0.7 0.074 12.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3521) DnaJ PF00226.26 EPS34348.1 - 1.8e-27 94.8 6.5 2.9e-27 94.1 4.5 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EPS34348.1 - 4.9e-24 84.0 2.9 4.8e-23 80.8 0.1 2.7 2 1 0 2 2 2 1 DnaJ C terminal domain Malate_DH PF12434.3 EPS34348.1 - 0.032 13.9 0.3 0.071 12.8 0.2 1.6 1 0 0 1 1 1 0 Malate dehydrogenase enzyme Peptidase_S10 PF00450.17 EPS34349.1 - 4.1e-85 286.4 2.9 1e-84 285.1 2.0 1.6 1 1 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EPS34350.1 - 7e-25 88.2 6.9 9.1e-25 87.8 4.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPS34350.1 - 1.3e-14 54.2 0.0 8.5e-12 45.1 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPS34350.1 - 2.2e-12 46.9 0.6 1.1e-11 44.7 0.4 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 EPS34350.1 - 0.0041 16.7 0.0 0.0093 15.5 0.0 1.6 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_4 PF08386.5 EPS34350.1 - 0.025 14.4 0.0 0.097 12.5 0.0 2.0 2 0 0 2 2 2 0 TAP-like protein Ndr PF03096.9 EPS34350.1 - 0.15 10.4 0.0 0.22 9.9 0.0 1.1 1 0 0 1 1 1 0 Ndr family Amidohydro_3 PF07969.6 EPS34352.1 - 8.5e-60 203.0 2.3 1e-59 202.8 1.6 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EPS34352.1 - 2.1e-10 40.2 0.3 5.8e-10 38.8 0.2 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EPS34352.1 - 4.9e-06 26.4 2.5 0.031 13.9 0.8 3.0 2 2 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EPS34352.1 - 0.0028 17.7 8.6 0.032 14.2 0.1 2.7 2 2 0 2 2 2 2 Amidohydrolase STE PF02200.11 EPS34354.1 - 6.5e-61 203.2 0.2 1.1e-60 202.5 0.1 1.4 1 0 0 1 1 1 1 STE like transcription factor zf-C2H2 PF00096.21 EPS34354.1 - 9.2e-12 44.5 9.6 1.7e-06 28.0 0.4 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EPS34354.1 - 1.6e-09 37.5 4.1 1.6e-09 37.5 2.9 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EPS34354.1 - 1.9e-09 37.1 10.0 0.00015 21.8 0.7 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EPS34354.1 - 0.015 15.1 0.4 0.039 13.8 0.0 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-TRAF PF02176.13 EPS34354.1 - 0.022 15.1 2.1 0.047 14.0 1.5 1.5 1 0 0 1 1 1 0 TRAF-type zinc finger zf-C2H2_jaz PF12171.3 EPS34354.1 - 0.063 13.4 0.2 1.7 8.9 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EPS34354.1 - 0.32 11.1 2.6 0.84 9.8 1.8 1.7 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2HC_2 PF13913.1 EPS34354.1 - 1.3 8.8 4.7 2.1 8.0 0.2 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type MFS_1 PF07690.11 EPS34356.1 - 1.5e-27 96.3 36.8 1.5e-27 96.3 25.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EPS34357.1 - 5.3e-11 41.5 7.1 5.3e-11 41.5 4.9 2.9 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_1 PF07690.11 EPS34357.1 - 2.3e-07 29.8 21.9 5.2e-06 25.4 8.3 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily Na_H_Exchanger PF00999.16 EPS34358.1 - 1.1e-68 231.4 39.3 1.4e-68 231.1 27.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family AA_permease_2 PF13520.1 EPS34359.1 - 4.7e-53 180.2 37.0 6.5e-53 179.7 25.7 1.1 1 0 0 1 1 1 1 Amino acid permease Herpes_US9 PF06072.6 EPS34359.1 - 4 7.3 5.8 10 6.0 0.0 3.6 4 0 0 4 4 4 0 Alphaherpesvirus tegument protein US9 Bestrophin PF01062.16 EPS34363.1 - 4.5e-52 176.8 0.6 1.3e-50 172.0 0.4 2.0 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Sugar_tr PF00083.19 EPS34365.1 - 1.8e-78 264.1 22.8 2.1e-78 263.9 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS34365.1 - 1e-12 47.5 39.9 5e-09 35.3 20.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Orthoreo_P17 PF07272.6 EPS34366.1 - 0.0072 16.1 0.0 0.0099 15.6 0.0 1.2 1 0 0 1 1 1 1 Orthoreovirus P17 protein GSH_synth_ATP PF03917.12 EPS34367.1 - 2.9e-99 332.1 0.0 3.6e-99 331.8 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EPS34367.1 - 6.9e-28 96.8 0.0 1.2e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase SNF2_N PF00176.18 EPS34368.1 - 8.5e-48 162.6 0.0 1.5e-47 161.8 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EPS34368.1 - 2.3e-13 49.7 0.0 7.4e-13 48.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SAM_2 PF07647.12 EPS34368.1 - 6.7e-05 22.6 0.0 0.00034 20.3 0.0 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) ResIII PF04851.10 EPS34368.1 - 0.00014 21.7 0.0 0.00037 20.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SAM_1 PF00536.25 EPS34368.1 - 0.013 15.6 0.0 0.056 13.6 0.0 2.2 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DEAD PF00270.24 EPS34368.1 - 0.017 14.5 0.0 0.063 12.7 0.0 1.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase HIRA_B PF09453.5 EPS34368.1 - 0.083 12.4 0.1 0.21 11.2 0.1 1.6 1 0 0 1 1 1 0 HIRA B motif BNR_2 PF13088.1 EPS34369.1 - 4.9e-07 29.3 0.0 0.049 12.9 0.0 3.3 1 1 2 3 3 3 3 BNR repeat-like domain Glyco_hydro_43 PF04616.9 EPS34369.1 - 0.0036 16.4 0.1 1.2 8.1 0.0 2.5 2 1 0 2 2 2 2 Glycosyl hydrolases family 43 BNR PF02012.15 EPS34369.1 - 0.012 15.2 7.9 0.24 11.3 0.1 3.5 4 0 0 4 4 4 0 BNR/Asp-box repeat SNF2_N PF00176.18 EPS34370.1 - 1.1e-68 231.2 0.0 1.8e-68 230.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 EPS34370.1 - 1.8e-16 60.0 0.0 3.9e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 EPS34370.1 - 6.2e-12 45.2 0.0 1.3e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 EPS34370.1 - 2.8e-11 43.0 8.8 7.1e-11 41.7 6.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EPS34370.1 - 5.5e-11 41.9 10.3 1.8e-10 40.3 5.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPS34370.1 - 8.6e-10 38.4 12.9 9.7e-10 38.3 6.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EPS34370.1 - 2.3e-09 36.7 10.4 2.3e-09 36.7 7.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EPS34370.1 - 5.9e-08 32.4 9.0 1.2e-07 31.4 6.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EPS34370.1 - 3e-07 30.0 8.6 7.4e-07 28.7 5.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EPS34370.1 - 7.6e-06 25.9 4.4 2.2e-05 24.4 3.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EPS34370.1 - 0.00027 20.5 5.7 0.0013 18.4 3.9 2.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 EPS34370.1 - 0.0008 18.8 6.1 0.0019 17.6 3.8 1.9 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 EPS34370.1 - 0.0029 17.3 3.7 0.0063 16.2 2.6 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein DUF778 PF05608.7 EPS34370.1 - 0.0045 16.9 0.0 0.77 9.7 0.0 3.0 3 1 0 3 3 3 1 Protein of unknown function (DUF778) zf-RING_4 PF14570.1 EPS34370.1 - 0.033 13.7 6.9 0.068 12.7 4.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF4082 PF13313.1 EPS34370.1 - 0.16 11.4 0.1 0.39 10.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4082) zf-Apc11 PF12861.2 EPS34370.1 - 0.19 11.5 2.0 0.55 10.1 1.4 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 EPS34370.1 - 0.21 11.1 3.8 0.5 9.9 2.6 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 MBOAT_2 PF13813.1 EPS34371.1 - 1e-18 67.1 5.6 1e-18 67.1 3.9 2.3 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family RIX1 PF08167.7 EPS34372.1 - 5.6e-59 198.5 3.3 6.9e-59 198.2 0.1 2.5 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis TPR_14 PF13428.1 EPS34373.1 - 8e-11 41.5 9.9 0.13 12.9 0.0 7.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.1 EPS34373.1 - 3.2e-08 33.3 7.4 0.058 13.3 0.0 5.2 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 EPS34373.1 - 1.7e-06 27.5 5.2 0.0063 16.1 0.0 5.3 5 0 0 5 5 5 1 TPR repeat TPR_8 PF13181.1 EPS34373.1 - 1.7e-06 27.3 0.2 12 5.9 0.0 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.12 EPS34373.1 - 1.9e-06 27.3 7.8 2.5 8.2 0.0 6.8 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.23 EPS34373.1 - 1.8e-05 24.1 0.6 3.5 7.3 0.0 5.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 EPS34373.1 - 3.5e-05 24.0 1.3 0.14 12.4 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 EPS34373.1 - 4.7e-05 23.2 1.0 3.2 8.1 0.0 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EPS34373.1 - 0.001 19.6 10.0 3.9 8.2 0.0 6.1 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 EPS34373.1 - 0.018 14.8 0.3 0.33 10.8 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat NDUFA12 PF05071.11 EPS34374.1 - 2.6e-25 88.9 1.9 3.4e-25 88.5 1.3 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PLDc_2 PF13091.1 EPS34375.1 - 5.8e-16 58.3 0.0 1.3e-08 34.6 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EPS34375.1 - 1.2e-09 37.6 1.3 0.0018 18.0 0.2 3.2 2 1 0 2 2 2 2 Phospholipase D Active site motif FA PF08736.6 EPS34375.1 - 0.045 13.5 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 FERM adjacent (FA) LTV PF04180.9 EPS34376.1 - 4.3e-75 253.8 11.9 5.1e-75 253.5 8.3 1.1 1 0 0 1 1 1 1 Low temperature viability protein RtcB PF01139.12 EPS34376.1 - 0.084 11.8 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 tRNA-splicing ligase RtcB MMR_HSR1 PF01926.18 EPS34377.1 - 8.9e-18 64.3 0.2 1.7e-14 53.7 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EPS34377.1 - 1.2e-06 27.8 0.2 5e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EPS34377.1 - 0.0007 18.8 0.0 0.0015 17.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EPS34377.1 - 0.0038 16.3 0.0 0.0089 15.1 0.0 1.6 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 EPS34377.1 - 0.0083 15.9 6.1 0.16 11.7 0.1 3.5 3 1 1 4 4 4 2 Dynamin family Miro PF08477.8 EPS34377.1 - 0.073 13.5 0.8 0.23 11.9 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein Acyl-CoA_dh_1 PF00441.19 EPS34378.1 - 2.9e-28 98.8 3.4 5e-28 98.0 2.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EPS34378.1 - 5e-16 57.9 0.0 1.2e-15 56.7 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EPS34378.1 - 5e-14 52.8 0.5 1e-13 51.8 0.4 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EPS34378.1 - 1.1e-13 51.6 3.5 1.9e-13 50.8 2.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Spo12 PF05032.7 EPS34379.1 - 1.3e-16 59.9 2.8 2.4e-16 59.0 2.0 1.5 1 0 0 1 1 1 1 Spo12 family Sad1_UNC PF07738.8 EPS34380.1 - 8e-34 116.3 0.0 1.5e-33 115.5 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Pkinase PF00069.20 EPS34381.1 - 1.8e-57 194.4 0.0 2.7e-57 193.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS34381.1 - 8.5e-36 123.3 0.0 1.2e-35 122.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPS34381.1 - 9.2e-10 37.9 0.0 8.7e-08 31.4 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EPS34381.1 - 0.061 12.3 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HSP9_HSP12 PF04119.7 EPS34384.1 - 0.07 13.2 1.4 3.2 7.9 0.3 2.1 2 0 0 2 2 2 0 Heat shock protein 9/12 Pep3_Vps18 PF05131.9 EPS34385.1 - 1e-44 151.5 0.0 5.2e-44 149.2 0.0 2.2 3 0 0 3 3 3 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 EPS34385.1 - 1.4e-09 37.6 8.5 1.8e-05 24.3 0.1 4.1 2 1 1 4 4 4 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 EPS34385.1 - 0.00023 20.9 0.5 0.00053 19.7 0.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EPS34385.1 - 0.00083 19.0 0.3 0.0019 17.8 0.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Vps39_2 PF10367.4 EPS34385.1 - 0.0068 16.5 0.0 0.019 15.1 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-C3HC4 PF00097.20 EPS34385.1 - 0.066 12.8 0.2 0.18 11.4 0.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2175 PF09943.4 EPS34385.1 - 0.07 13.1 0.2 0.25 11.3 0.1 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) zf-C3HC4_2 PF13923.1 EPS34385.1 - 0.13 12.3 0.4 0.29 11.2 0.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Mit_ribos_Mrp51 PF11709.3 EPS34385.1 - 0.14 11.3 0.1 0.29 10.3 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit UCH_1 PF13423.1 EPS34386.1 - 6.1e-74 249.1 0.0 3.4e-73 246.6 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.24 EPS34386.1 - 1.4e-16 60.4 0.0 4.9e-16 58.6 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_L5_C PF00673.16 EPS34387.1 - 1.7e-24 85.3 0.0 2.8e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Pkinase PF00069.20 EPS34388.1 - 2e-66 223.8 0.0 3.6e-66 222.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS34388.1 - 3.9e-49 167.0 0.0 1.2e-48 165.4 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 EPS34388.1 - 4.2e-30 103.7 0.0 9.6e-30 102.6 0.0 1.6 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_1 PF00536.25 EPS34388.1 - 3e-14 52.9 0.9 4.6e-14 52.3 0.1 1.8 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EPS34388.1 - 4.8e-12 45.5 0.1 1.1e-11 44.3 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 EPS34388.1 - 1.5e-08 33.9 0.0 5.4e-05 22.2 0.0 2.3 2 0 0 2 2 2 2 Kinase-like RA PF00788.18 EPS34388.1 - 0.00047 20.6 0.0 0.00089 19.7 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kdo PF06293.9 EPS34388.1 - 0.023 13.7 0.0 0.044 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CUE PF02845.11 EPS34388.1 - 0.045 13.2 0.2 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 CUE domain Seadorna_VP7 PF07387.6 EPS34388.1 - 0.067 12.0 0.0 0.15 10.8 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 Transferase PF02458.10 EPS34389.1 - 9.5e-30 103.3 0.0 1.2e-14 53.6 0.0 3.2 3 0 0 3 3 3 3 Transferase family Glyco_transf_90 PF05686.7 EPS34390.1 - 4.2e-20 71.8 2.3 1.3e-17 63.5 1.3 3.3 2 1 0 2 2 2 2 Glycosyl transferase family 90 zf-C2H2 PF00096.21 EPS34391.1 - 3.6e-12 45.8 8.6 2e-05 24.6 1.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPS34391.1 - 3.3e-09 36.4 8.3 0.00027 21.0 2.1 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EPS34391.1 - 7.3e-09 35.4 2.4 7.3e-09 35.4 1.6 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EPS34391.1 - 7e-05 22.8 2.0 0.27 11.4 0.5 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 EPS34391.1 - 0.00023 20.7 1.9 0.21 11.2 0.1 2.8 2 0 0 2 2 2 2 zinc-finger of a C2HC-type zf-C2H2_6 PF13912.1 EPS34391.1 - 0.026 14.4 4.4 1.5 8.8 0.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.7 EPS34391.1 - 0.044 13.8 2.0 0.094 12.8 1.4 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 EPS34391.1 - 0.1 12.8 3.8 7.9 6.8 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type KAP_NTPase PF07693.9 EPS34391.1 - 0.2 10.5 0.0 0.34 9.8 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain zf-FCS PF06467.9 EPS34392.1 - 0.043 13.4 0.2 0.093 12.3 0.1 1.6 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif DUF629 PF04780.7 EPS34392.1 - 0.73 8.2 7.8 2.1 6.7 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-C2H2_4 PF13894.1 EPS34392.1 - 1.5 9.3 18.3 0.14 12.5 1.5 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EPS34392.1 - 1.5 9.2 16.9 0.12 12.7 1.4 3.7 3 1 0 3 3 3 0 Zinc finger, C2H2 type EST1_DNA_bind PF10373.4 EPS34393.1 - 7.5e-64 215.6 0.0 1.4e-63 214.7 0.0 1.5 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 EPS34393.1 - 1.4e-21 76.8 0.4 3e-21 75.7 0.3 1.6 1 0 0 1 1 1 1 Telomerase activating protein Est1 TPR_11 PF13414.1 EPS34393.1 - 0.0074 15.9 0.1 0.016 14.8 0.1 1.5 1 0 0 1 1 1 1 TPR repeat PfkB PF00294.19 EPS34394.1 - 9.2e-65 218.7 0.1 1.1e-64 218.4 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EPS34394.1 - 0.041 13.0 0.0 0.083 12.0 0.0 1.5 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase DUF1770 PF08589.5 EPS34395.1 - 1.8e-26 92.6 0.5 2.3e-26 92.2 0.3 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) WHIM1 PF15612.1 EPS34396.1 - 5e-05 23.0 0.0 0.00013 21.6 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Ribosomal_L2_C PF03947.13 EPS34397.1 - 7.7e-39 132.4 3.9 1.3e-38 131.7 2.7 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EPS34397.1 - 5.8e-13 48.6 0.2 1.4e-12 47.4 0.1 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain BAR PF03114.13 EPS34398.1 - 4.9e-49 166.9 4.0 4.9e-49 166.9 2.8 1.5 2 0 0 2 2 2 1 BAR domain BAR_2 PF10455.4 EPS34398.1 - 4.9e-07 28.9 1.6 6.6e-07 28.5 1.1 1.2 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking SNF2_N PF00176.18 EPS34399.1 - 6.9e-84 281.1 1.0 6.9e-84 281.1 0.7 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 EPS34399.1 - 3.7e-21 74.8 0.2 3.7e-21 74.8 0.1 2.2 2 0 0 2 2 2 1 Bromodomain Helicase_C PF00271.26 EPS34399.1 - 3.2e-18 65.3 0.6 1.1e-16 60.4 0.0 3.6 4 0 0 4 4 4 1 Helicase conserved C-terminal domain HSA PF07529.8 EPS34399.1 - 3e-14 52.5 12.7 3e-14 52.5 8.8 3.4 3 0 0 3 3 3 1 HSA SnAC PF14619.1 EPS34399.1 - 4.2e-12 46.0 3.7 4.2e-12 46.0 2.6 4.1 3 1 1 4 4 4 2 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.6 EPS34399.1 - 5.7e-11 41.6 0.9 1.5e-10 40.3 0.6 1.8 1 0 0 1 1 1 1 QLQ DEAD PF00270.24 EPS34399.1 - 6.7e-06 25.6 0.7 0.00015 21.3 0.0 2.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Abhydro_lipase PF04083.11 EPS34400.1 - 2.7e-21 74.6 0.3 6.4e-21 73.4 0.0 1.8 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 EPS34400.1 - 1.5e-15 57.3 0.1 2.4e-15 56.7 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EPS34400.1 - 8.1e-06 25.8 0.0 1.4e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPS34400.1 - 0.0021 17.8 0.0 0.015 15.0 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EPS34400.1 - 0.011 15.2 0.1 4.2 6.7 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase (FSH1) TRIC PF05197.8 EPS34400.1 - 0.69 9.2 3.1 0.3 10.4 0.1 1.8 2 0 0 2 2 2 0 TRIC channel Pet191_N PF10203.4 EPS34401.1 - 1e-29 102.3 5.0 1.3e-29 101.9 3.4 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 EPS34401.1 - 0.049 13.3 3.1 2.9 7.7 0.2 2.5 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like PAN_3 PF08277.7 EPS34401.1 - 0.12 11.9 0.2 0.24 11.0 0.2 1.5 1 0 0 1 1 1 0 PAN-like domain DDOST_48kD PF03345.9 EPS34402.1 - 6.5e-166 552.0 0.0 7.3e-166 551.8 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF1116 PF06545.6 EPS34402.1 - 0.092 11.8 0.0 0.58 9.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1116) IMS PF00817.15 EPS34406.1 - 4.5e-38 130.3 0.0 6.4e-37 126.6 0.0 2.3 1 1 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EPS34406.1 - 1.4e-13 50.9 0.0 2.6e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain Rsa3 PF14615.1 EPS34408.1 - 0.14 11.4 0.1 0.67 9.2 0.1 2.0 1 1 0 1 1 1 0 Ribosome-assembly protein 3 WSC PF01822.14 EPS34409.1 - 1.9e-09 37.3 13.9 1.9e-09 37.3 9.6 2.5 2 1 0 2 2 2 1 WSC domain Myc_target_1 PF15179.1 EPS34409.1 - 0.0078 15.8 8.0 0.015 14.8 0.1 2.2 2 0 0 2 2 2 1 Myc target protein 1 Mid2 PF04478.7 EPS34409.1 - 0.012 15.0 1.3 0.012 15.0 0.9 2.7 2 1 0 3 3 3 0 Mid2 like cell wall stress sensor Amnionless PF14828.1 EPS34409.1 - 0.022 13.2 0.0 0.034 12.6 0.0 1.3 1 0 0 1 1 1 0 Amnionless Apc1 PF12859.2 EPS34409.1 - 0.069 13.3 5.3 0.96 9.7 2.1 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 1 Pex14_N PF04695.8 EPS34409.1 - 0.19 11.7 7.4 0.42 10.6 5.1 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4614 PF15391.1 EPS34409.1 - 0.38 10.5 12.1 0.71 9.6 8.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Macoilin PF09726.4 EPS34409.1 - 0.47 8.6 4.7 0.47 8.6 3.2 1.1 1 0 0 1 1 1 0 Transmembrane protein SOG2 PF10428.4 EPS34409.1 - 1.1 7.8 11.5 1.6 7.3 8.0 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Ank_2 PF12796.2 EPS34410.1 - 6.4e-36 122.5 0.7 1e-13 51.4 0.0 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPS34410.1 - 9.2e-27 92.9 0.5 6.5e-07 29.7 0.2 5.6 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.25 EPS34410.1 - 7.8e-25 85.4 10.0 2.4e-09 36.5 0.1 7.9 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.1 EPS34410.1 - 1.4e-24 85.5 1.6 5.8e-09 35.9 0.3 6.0 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPS34410.1 - 6.8e-24 81.5 0.5 2.2e-05 24.2 0.0 7.9 8 0 0 8 8 8 5 Ankyrin repeat F-box PF00646.28 EPS34410.1 - 2.7e-05 23.7 0.1 6.2e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EPS34410.1 - 9.2e-05 22.0 0.2 9.2e-05 22.0 0.1 1.7 2 0 0 2 2 2 1 F-box-like UPF0075 PF03702.9 EPS34410.1 - 0.056 12.3 0.1 0.11 11.3 0.0 1.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0075) F-box-like_2 PF13013.1 EPS34410.1 - 0.12 12.1 0.1 0.23 11.1 0.1 1.5 1 0 0 1 1 1 0 F-box-like domain Ank_2 PF12796.2 EPS34411.1 - 3.2e-31 107.5 2.7 3e-12 46.7 0.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EPS34411.1 - 5.9e-27 93.5 3.8 3.7e-08 33.6 0.0 5.5 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPS34411.1 - 1.2e-21 76.1 5.1 8.8e-05 22.6 0.1 5.6 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPS34411.1 - 8.4e-21 71.9 4.1 0.018 15.2 0.0 8.5 7 1 0 7 7 7 5 Ankyrin repeat Ank PF00023.25 EPS34411.1 - 2e-19 68.3 18.9 0.0038 16.9 0.3 8.7 7 1 0 7 7 7 5 Ankyrin repeat F-box-like PF12937.2 EPS34411.1 - 0.00014 21.5 0.0 0.0003 20.4 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EPS34411.1 - 0.00029 20.4 0.0 0.00067 19.2 0.0 1.6 1 0 0 1 1 1 1 F-box domain Sugar_tr PF00083.19 EPS34413.1 - 1e-120 403.4 20.6 1.6e-120 402.7 14.3 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS34413.1 - 2.6e-29 102.0 51.6 1.5e-24 86.3 21.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily OTT_1508_deam PF14441.1 EPS34414.1 - 4.6e-12 45.9 0.0 1.2e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 OTT_1508-like deaminase DYW_deaminase PF14432.1 EPS34414.1 - 0.015 15.3 3.2 0.019 14.9 0.3 2.3 2 0 0 2 2 2 0 DYW family of nucleic acid deaminases DUF3445 PF11927.3 EPS34415.1 - 9.5e-78 261.0 0.1 1.4e-77 260.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) adh_short PF00106.20 EPS34416.1 - 4.2e-24 85.3 1.5 5.6e-24 84.9 1.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPS34416.1 - 1.4e-17 64.2 0.4 2e-17 63.7 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EPS34416.1 - 4.4e-06 26.2 0.2 1.1e-05 24.9 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EPS34416.1 - 5.9e-05 22.8 0.6 9.3e-05 22.1 0.4 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EPS34416.1 - 0.00034 19.8 0.0 0.00051 19.2 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EPS34416.1 - 0.00045 20.2 0.5 0.0044 17.0 0.3 2.4 2 1 0 2 2 2 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EPS34416.1 - 0.00047 19.1 0.0 0.00068 18.6 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EPS34416.1 - 0.005 16.6 0.3 0.013 15.2 0.1 1.9 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DASH_Spc19 PF08287.6 EPS34416.1 - 0.079 12.5 0.0 0.37 10.4 0.0 1.9 2 0 0 2 2 2 0 Spc19 PRP38 PF03371.10 EPS34417.1 - 1.7e-66 223.0 0.0 2.1e-66 222.7 0.0 1.1 1 0 0 1 1 1 1 PRP38 family WD40 PF00400.27 EPS34419.1 - 2e-19 68.6 3.4 0.0032 17.3 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat AAA_12 PF13087.1 EPS34420.1 - 2e-23 82.7 0.1 3.1e-15 56.1 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_11 PF13086.1 EPS34420.1 - 1.2e-10 41.4 1.8 7.1e-10 38.8 1.3 2.1 1 1 0 1 1 1 1 AAA domain zf-C2H2 PF00096.21 EPS34422.1 - 3e-08 33.5 10.8 2.1e-05 24.6 2.4 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EPS34422.1 - 2.7e-07 30.4 9.5 0.00019 21.5 2.9 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EPS34422.1 - 4.7e-05 23.4 2.2 4.7e-05 23.4 1.5 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-UBR PF02207.15 EPS34422.1 - 0.048 13.3 1.2 0.079 12.6 0.8 1.2 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) zf-C2HC_2 PF13913.1 EPS34422.1 - 0.25 11.0 2.4 0.52 10.0 1.6 1.5 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-BED PF02892.10 EPS34422.1 - 3.1 7.6 5.2 0.47 10.2 0.8 1.7 2 0 0 2 2 2 0 BED zinc finger adh_short PF00106.20 EPS34423.1 - 1.2e-24 87.1 0.5 2.3e-24 86.2 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPS34423.1 - 5e-22 78.8 0.0 6.2e-22 78.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPS34423.1 - 3.7e-07 29.9 1.2 6.4e-07 29.2 0.1 1.9 2 1 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 EPS34423.1 - 0.0013 17.7 0.0 0.003 16.5 0.0 1.5 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 EPS34423.1 - 0.0063 16.1 0.2 0.01 15.5 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 EPS34423.1 - 0.0095 15.7 0.7 0.023 14.5 0.4 1.7 1 1 0 1 1 1 1 ThiF family Amidase PF01425.16 EPS34424.1 - 2.1e-92 310.2 0.2 2.7e-92 309.9 0.1 1.1 1 0 0 1 1 1 1 Amidase Polysacc_deac_1 PF01522.16 EPS34425.1 - 1.8e-22 79.2 0.0 3.6e-22 78.2 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Parvo_coat PF00740.13 EPS34425.1 - 0.0097 14.9 0.1 0.012 14.6 0.1 1.1 1 0 0 1 1 1 1 Parvovirus coat protein VP2 DUF2334 PF10096.4 EPS34425.1 - 0.032 13.6 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) Aa_trans PF01490.13 EPS34426.1 - 8.2e-28 97.0 32.2 1e-27 96.6 22.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 EPS34426.1 - 2.2e-06 26.4 22.5 2.2e-06 26.4 15.6 2.3 1 1 0 2 2 2 1 Amino acid permease Bromo_coat PF01318.13 EPS34426.1 - 0.019 14.7 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Bromovirus coat protein ABC_tran PF00005.22 EPS34428.1 - 1.8e-54 183.7 0.0 9.4e-32 110.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EPS34428.1 - 1.4e-44 152.5 29.3 3.3e-26 92.3 2.5 4.1 4 0 0 4 4 4 3 ABC transporter transmembrane region SMC_N PF02463.14 EPS34428.1 - 4e-07 29.4 1.9 0.078 12.2 0.1 4.1 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EPS34428.1 - 4.4e-07 30.1 0.5 0.24 11.3 0.0 3.6 3 1 0 3 3 2 2 AAA domain AAA_25 PF13481.1 EPS34428.1 - 6e-07 29.0 0.1 0.027 13.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EPS34428.1 - 1.2e-06 29.0 0.1 0.00094 19.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EPS34428.1 - 6.4e-06 26.2 0.3 0.06 13.3 0.1 3.0 2 1 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 EPS34428.1 - 3.6e-05 23.7 0.1 0.019 14.9 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase T2SE PF00437.15 EPS34428.1 - 7.5e-05 21.7 0.0 0.01 14.7 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_29 PF13555.1 EPS34428.1 - 0.00017 21.0 2.8 0.3 10.6 0.0 3.4 3 0 0 3 3 3 2 P-loop containing region of AAA domain DUF258 PF03193.11 EPS34428.1 - 0.00025 20.2 0.1 0.42 9.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EPS34428.1 - 0.00026 20.1 1.9 0.1 11.7 0.1 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_17 PF13207.1 EPS34428.1 - 0.00028 21.7 0.2 1.5 9.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EPS34428.1 - 0.00075 19.9 0.1 2.7 8.5 0.1 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_10 PF12846.2 EPS34428.1 - 0.00077 18.9 0.1 0.88 8.9 0.0 2.7 3 0 0 3 3 2 2 AAA-like domain DUF87 PF01935.12 EPS34428.1 - 0.0013 18.5 1.0 0.043 13.6 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_22 PF13401.1 EPS34428.1 - 0.0016 18.5 3.2 3.6 7.7 0.3 3.5 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EPS34428.1 - 0.0027 17.9 0.3 2.6 8.3 0.0 3.1 3 0 0 3 3 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EPS34428.1 - 0.0041 16.6 0.1 0.76 9.2 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family IstB_IS21 PF01695.12 EPS34428.1 - 0.0095 15.3 0.2 1.8 7.9 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein NACHT PF05729.7 EPS34428.1 - 0.027 14.1 1.2 0.6 9.7 0.0 2.5 2 0 0 2 2 2 0 NACHT domain TrwB_AAD_bind PF10412.4 EPS34428.1 - 0.062 11.9 1.5 6.2 5.3 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ATP-synt_ab PF00006.20 EPS34428.1 - 0.067 12.6 0.1 3.2 7.1 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MobB PF03205.9 EPS34428.1 - 0.083 12.5 0.3 11 5.7 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 EPS34428.1 - 0.085 13.0 1.2 6.8 6.8 0.1 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Pox_A32 PF04665.7 EPS34428.1 - 0.12 11.7 0.5 8.3 5.6 0.0 2.9 3 0 0 3 3 3 0 Poxvirus A32 protein Sigma54_activat PF00158.21 EPS34428.1 - 0.14 11.6 0.0 0.75 9.2 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain Dynamin_N PF00350.18 EPS34428.1 - 0.16 11.7 1.6 9.7 5.9 0.0 3.0 3 0 0 3 3 3 0 Dynamin family UPF0079 PF02367.12 EPS34428.1 - 0.22 11.1 1.6 19 4.9 0.2 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 cobW PF02492.14 EPS34428.1 - 0.26 10.7 1.9 1.1 8.6 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TIP49 PF06068.8 EPS34428.1 - 4.1 5.9 5.4 16 4.0 0.0 2.7 3 0 0 3 3 3 0 TIP49 C-terminus UQ_con PF00179.21 EPS34429.1 - 1.5e-31 108.7 0.0 1.9e-31 108.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Sugar_tr PF00083.19 EPS34431.1 - 1.8e-78 264.1 22.5 2.3e-78 263.8 15.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS34431.1 - 1.8e-38 132.1 44.2 1.8e-33 115.7 17.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EPS34431.1 - 0.00087 17.6 1.6 0.00087 17.6 1.1 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 EPS34431.1 - 0.0089 15.8 0.4 3.3 7.5 0.0 3.0 2 1 0 2 2 2 2 MFS_1 like family Nitroreductase PF00881.19 EPS34431.1 - 0.075 12.8 0.1 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 Nitroreductase family DUF1201 PF06716.6 EPS34431.1 - 0.18 11.6 2.7 2.4 8.0 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) Peptidase_S8 PF00082.17 EPS34432.1 - 9.1e-55 185.7 11.6 9.1e-55 185.7 8.1 1.8 2 0 0 2 2 2 1 Subtilase family Inhibitor_I9 PF05922.11 EPS34432.1 - 9.9e-19 67.6 0.8 2.2e-18 66.6 0.6 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Beach PF02138.13 EPS34433.1 - 1.7e-109 365.4 0.1 4.6e-109 364.0 0.0 1.8 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.1 EPS34433.1 - 1.9e-12 46.9 0.0 4.4e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 EPS34433.1 - 1.7e-10 40.3 1.0 0.00067 19.4 0.0 4.0 3 0 0 3 3 3 2 WD domain, G-beta repeat Laminin_G_3 PF13385.1 EPS34433.1 - 3.6e-10 40.3 0.0 1.2e-09 38.6 0.0 1.8 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Transaldolase PF00923.14 EPS34434.1 - 1e-96 323.4 0.3 1.2e-96 323.2 0.2 1.0 1 0 0 1 1 1 1 Transaldolase C5-epim_C PF06662.8 EPS34434.1 - 0.09 12.0 0.0 0.21 10.8 0.0 1.5 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus Sod_Cu PF00080.15 EPS34435.1 - 1.9e-44 151.2 4.4 2.3e-44 151.0 3.0 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) SNase PF00565.12 EPS34436.1 - 6.2e-76 251.6 0.0 6.7e-25 87.4 0.0 5.6 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 EPS34436.1 - 5.8e-24 84.2 0.0 1.8e-23 82.6 0.0 1.9 2 0 0 2 2 2 1 Tudor domain SMN PF06003.7 EPS34436.1 - 0.00017 20.8 0.0 0.00037 19.6 0.0 1.5 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) CRAL_TRIO PF00650.15 EPS34437.1 - 5.3e-26 91.0 0.0 7.2e-26 90.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EPS34437.1 - 4.6e-09 36.2 0.0 1e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EPS34437.1 - 0.15 11.9 0.0 1.2 9.0 0.0 2.0 1 1 0 1 1 1 0 Divergent CRAL/TRIO domain FA_hydroxylase PF04116.8 EPS34438.1 - 5.2e-13 49.3 12.6 5.2e-13 49.3 8.7 2.4 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Dynamin_N PF00350.18 EPS34439.1 - 2.7e-14 53.3 0.4 4.7e-07 29.7 0.0 3.1 4 0 0 4 4 4 2 Dynamin family MMR_HSR1 PF01926.18 EPS34439.1 - 3e-07 30.4 0.0 0.00066 19.6 0.0 3.3 3 0 0 3 3 3 2 50S ribosome-binding GTPase DUF258 PF03193.11 EPS34439.1 - 1.9e-05 23.9 0.0 0.00033 19.8 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EPS34439.1 - 3.6e-05 24.0 0.1 0.00012 22.3 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.1 EPS34439.1 - 0.00024 21.1 0.9 0.0015 18.5 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain AIG1 PF04548.11 EPS34439.1 - 0.001 18.1 0.0 0.0059 15.7 0.0 2.1 2 0 0 2 2 2 1 AIG1 family AAA_18 PF13238.1 EPS34439.1 - 0.012 15.9 0.0 0.14 12.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EPS34439.1 - 0.018 14.5 0.1 0.039 13.4 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.17 EPS34439.1 - 0.04 12.7 0.0 0.088 11.6 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.1 EPS34439.1 - 0.044 13.9 0.0 1.3 9.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EPS34439.1 - 0.05 14.1 0.0 0.15 12.5 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein AAA_17 PF13207.1 EPS34439.1 - 0.08 13.7 0.4 0.5 11.1 0.0 2.7 4 0 0 4 4 2 0 AAA domain DUF87 PF01935.12 EPS34439.1 - 0.35 10.6 11.6 3 7.6 0.2 3.7 3 1 0 3 3 3 0 Domain of unknown function DUF87 Glycos_transf_3 PF00591.16 EPS34440.1 - 1.6e-56 191.5 0.0 2.7e-55 187.5 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 EPS34440.1 - 1.7e-08 33.9 0.2 4.4e-08 32.5 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain DUF1620 PF07774.8 EPS34441.1 - 1.6e-72 243.2 0.0 2.9e-72 242.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 EPS34441.1 - 3e-21 75.9 20.9 4.6e-21 75.3 1.8 3.9 3 1 1 4 4 4 3 PQQ-like domain PQQ PF01011.16 EPS34441.1 - 3.4e-05 23.1 0.2 14 5.3 0.0 6.2 7 0 0 7 7 7 2 PQQ enzyme repeat Ribonuc_L-PSP PF01042.16 EPS34442.1 - 3.6e-11 42.8 0.0 4.9e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Chitin_synth_1 PF01644.12 EPS34443.1 - 3e-68 228.7 0.0 5.4e-68 227.9 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EPS34443.1 - 1.6e-26 91.8 0.0 4.7e-26 90.2 0.0 1.8 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EPS34443.1 - 3.6e-24 85.0 1.1 6.8e-20 70.9 0.0 2.1 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EPS34443.1 - 5.7e-11 42.4 0.3 5.7e-11 42.4 0.2 3.1 2 1 1 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EPS34443.1 - 8.5e-07 29.0 0.0 2.9e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 DUF1479 PF07350.7 EPS34444.1 - 2.3e-165 550.1 0.0 2.6e-165 549.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) DUF260 PF03195.9 EPS34444.1 - 0.13 12.5 0.0 0.36 11.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF260 Pkinase PF00069.20 EPS34445.1 - 7e-13 48.3 0.0 1.4e-12 47.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS34445.1 - 1.5e-09 37.3 0.0 1.1e-08 34.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPS34445.1 - 7.2e-05 21.8 0.0 0.0012 17.8 0.0 2.0 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EPS34445.1 - 0.14 11.1 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EPS34445.1 - 0.16 11.3 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Aa_trans PF01490.13 EPS34448.1 - 1.2e-97 327.0 13.6 1.8e-97 326.4 9.4 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EPS34448.1 - 2.7e-05 23.1 16.1 2.7e-05 23.1 11.2 1.9 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family Bax1-I PF01027.15 EPS34449.1 - 1.7e-47 161.6 32.6 2e-47 161.4 22.6 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Peroxidase_2 PF01328.12 EPS34450.1 - 3.7e-44 150.6 0.3 4.2e-44 150.5 0.2 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 EXS PF03124.9 EPS34451.1 - 1.7e-89 300.2 32.8 2.2e-89 299.8 22.7 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.14 EPS34451.1 - 9.4e-54 183.0 4.1 9.4e-54 183.0 2.8 2.8 2 1 0 2 2 2 1 SPX domain Osteopontin PF00865.13 EPS34451.1 - 0.82 8.8 11.0 1.6 7.9 7.6 1.4 1 0 0 1 1 1 0 Osteopontin Glyco_hydro_15 PF00723.16 EPS34453.1 - 1.5e-103 346.7 0.2 1.9e-103 346.4 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 EPS34453.1 - 2.1e-37 126.5 0.6 7e-37 124.9 0.4 1.9 1 0 0 1 1 1 1 Starch binding domain CBM_25 PF03423.8 EPS34453.1 - 0.028 14.5 0.5 0.062 13.3 0.0 1.8 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) Abhydrolase_2 PF02230.11 EPS34454.1 - 1.3e-16 60.7 0.0 1.7e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EPS34454.1 - 4.7e-08 33.1 0.3 6.6e-05 22.8 0.2 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPS34454.1 - 5.1e-07 29.5 0.1 7.7e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EPS34454.1 - 0.14 11.5 0.0 0.42 10.0 0.0 1.8 1 1 0 1 1 1 0 Serine hydrolase (FSH1) MAPEG PF01124.13 EPS34455.1 - 1.8e-19 69.6 0.1 2e-19 69.4 0.0 1.0 1 0 0 1 1 1 1 MAPEG family Fungal_trans PF04082.13 EPS34456.1 - 7.9e-11 41.3 0.2 1.1e-10 40.8 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EPS34459.1 - 4.8e-07 29.7 14.2 0.0014 18.8 0.2 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type Fungal_trans PF04082.13 EPS34459.1 - 1.6e-06 27.1 0.1 2.5e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS34459.1 - 9.7e-06 25.3 7.9 9.7e-06 25.3 5.5 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 EPS34459.1 - 7e-05 22.8 11.6 0.00045 20.3 0.4 3.9 5 0 0 5 5 5 2 C2H2-type zinc finger PyrI_C PF02748.10 EPS34459.1 - 0.0071 15.7 1.6 0.014 14.8 0.3 2.1 2 0 0 2 2 2 1 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-Di19 PF05605.7 EPS34459.1 - 1.5 8.9 8.7 0.21 11.7 0.7 1.8 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding MFS_1 PF07690.11 EPS34460.1 - 5.2e-39 133.9 58.8 1.9e-38 132.0 25.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EPS34460.1 - 3.9e-05 22.0 4.9 3.9e-05 22.0 3.4 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EPS34460.1 - 0.55 8.2 12.3 0.0069 14.5 1.7 2.0 2 0 0 2 2 2 0 Transmembrane secretion effector Lactamase_B_2 PF12706.2 EPS34461.1 - 2.5e-26 92.4 0.0 3.4e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EPS34461.1 - 8.9e-10 38.5 0.0 1.2e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain TPR_2 PF07719.12 EPS34463.1 - 1.4e-11 43.3 5.5 0.00013 21.5 0.0 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.1 EPS34463.1 - 4.6e-09 35.8 12.1 1.5e-05 24.5 0.5 5.5 6 1 0 6 6 6 3 TPR repeat TPR_12 PF13424.1 EPS34463.1 - 7.7e-08 32.1 6.1 0.12 12.3 0.0 5.8 6 2 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 EPS34463.1 - 9e-08 31.4 2.2 0.0039 16.7 0.0 5.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 EPS34463.1 - 5.9e-05 22.5 0.1 0.39 10.5 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EPS34463.1 - 7.5e-05 22.2 3.0 1.3 9.0 0.0 5.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 EPS34463.1 - 0.00023 21.5 5.7 18 6.2 0.0 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.9 EPS34463.1 - 0.00026 21.1 1.4 0.54 10.8 0.0 4.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EPS34463.1 - 0.015 15.1 0.4 0.11 12.3 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EPS34463.1 - 1.7 9.3 22.1 4.8 7.9 0.2 7.2 7 2 1 9 9 7 0 Tetratricopeptide repeat TPR_10 PF13374.1 EPS34463.1 - 3.6 7.6 5.8 30 4.7 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF1814 PF08843.6 EPS34464.1 - 0.013 15.2 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF1814) TPR_10 PF13374.1 EPS34465.1 - 1.3e-28 98.0 0.0 1.8e-12 46.7 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EPS34465.1 - 2e-21 75.6 0.7 6.8e-12 45.1 0.1 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EPS34465.1 - 9.2e-09 34.4 0.4 0.064 13.0 0.0 4.2 4 0 0 4 4 3 2 Tetratricopeptide repeat NB-ARC PF00931.17 EPS34465.1 - 1.6e-07 30.4 0.1 7.6e-06 24.9 0.1 2.2 1 1 0 1 1 1 1 NB-ARC domain TPR_17 PF13431.1 EPS34465.1 - 1.1e-05 25.1 0.4 0.083 13.1 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EPS34465.1 - 0.00017 21.2 0.1 0.62 10.1 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EPS34465.1 - 0.00045 19.8 0.0 0.0096 15.5 0.0 2.8 2 1 1 3 3 3 1 TPR repeat TPR_4 PF07721.9 EPS34465.1 - 0.0015 18.8 4.5 0.43 11.1 0.3 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EPS34465.1 - 0.0029 17.1 0.0 19 5.0 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_22 PF13401.1 EPS34465.1 - 0.0057 16.7 0.0 0.016 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain TPR_19 PF14559.1 EPS34465.1 - 0.009 16.3 0.2 0.15 12.4 0.0 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat AAA_16 PF13191.1 EPS34465.1 - 0.011 15.6 1.1 0.32 10.9 0.7 2.7 1 1 0 1 1 1 0 AAA ATPase domain TPR_6 PF13174.1 EPS34465.1 - 0.022 15.1 0.6 2.1 8.9 0.1 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat PPR PF01535.15 EPS34465.1 - 0.041 13.8 0.1 17 5.6 0.0 2.9 2 0 0 2 2 2 0 PPR repeat TPR_16 PF13432.1 EPS34465.1 - 0.086 13.5 1.0 0.69 10.6 0.0 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EPS34465.1 - 0.1 13.2 7.0 3.8 8.3 0.1 5.0 6 1 1 7 7 4 0 Tetratricopeptide repeat PRELI PF04707.9 EPS34466.1 - 0.024 14.2 0.7 0.045 13.3 0.0 1.8 2 0 0 2 2 2 0 PRELI-like family K1 PF02960.9 EPS34466.1 - 0.079 12.9 0.2 9.1 6.3 0.0 2.3 2 0 0 2 2 2 0 K1 glycoprotein DUF3782 PF12644.2 EPS34466.1 - 0.3 10.9 6.8 0.55 10.0 0.5 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3782) Methyltransf_32 PF13679.1 EPS34467.1 - 5.9e-20 71.3 2.3 2e-19 69.6 1.6 1.9 1 1 0 1 1 1 1 Methyltransferase domain Syntaxin-6_N PF09177.6 EPS34468.1 - 1.8e-24 85.9 1.1 5.6e-24 84.3 0.2 2.1 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 EPS34468.1 - 7.5e-17 60.7 3.0 7.5e-17 60.7 2.1 2.9 3 0 0 3 3 3 1 SNARE domain NPV_P10 PF05531.7 EPS34468.1 - 0.00071 19.7 3.8 1.1 9.5 0.0 3.5 4 0 0 4 4 3 1 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.7 EPS34468.1 - 0.0091 15.7 1.1 0.52 10.0 0.2 2.3 2 0 0 2 2 2 1 Laminin Domain II DUF4164 PF13747.1 EPS34468.1 - 0.014 15.5 9.0 0.19 11.9 0.3 3.0 2 2 0 2 2 2 0 Domain of unknown function (DUF4164) Reo_sigmaC PF04582.7 EPS34468.1 - 0.048 12.8 0.0 0.78 8.8 0.0 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein GCIP PF13324.1 EPS34468.1 - 0.073 12.2 0.3 0.13 11.5 0.2 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting Baculo_PEP_C PF04513.7 EPS34468.1 - 0.08 12.7 1.7 1 9.1 0.3 2.5 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3618 PF12277.3 EPS34468.1 - 0.13 12.3 7.0 1 9.4 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3618) TBPIP PF07106.8 EPS34468.1 - 0.17 11.3 3.1 0.68 9.4 0.6 2.4 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF972 PF06156.8 EPS34468.1 - 0.26 11.6 2.0 1.4 9.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) THOC7 PF05615.8 EPS34468.1 - 0.3 11.3 3.2 0.56 10.4 0.2 2.1 1 1 1 2 2 2 0 Tho complex subunit 7 UPF0184 PF03670.8 EPS34468.1 - 0.46 10.6 5.2 3.7 7.7 0.0 3.6 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0184) TMF_DNA_bd PF12329.3 EPS34468.1 - 0.63 9.8 4.8 2.3 8.0 0.3 3.1 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding APG6 PF04111.7 EPS34468.1 - 0.68 8.9 4.0 0.61 9.0 0.2 2.0 1 1 0 2 2 2 0 Autophagy protein Apg6 Spc24 PF08286.6 EPS34468.1 - 0.74 9.5 5.5 15 5.3 0.2 3.1 2 1 0 3 3 3 0 Spc24 subunit of Ndc80 CENP-Q PF13094.1 EPS34468.1 - 0.77 9.7 5.8 1.8 8.5 4.0 1.7 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Seryl_tRNA_N PF02403.17 EPS34468.1 - 1 9.3 3.9 16 5.5 0.1 3.0 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain NAP PF00956.13 EPS34469.1 - 3.7e-37 127.7 12.4 3.7e-37 127.7 8.6 1.9 1 1 1 2 2 2 1 Nucleosome assembly protein (NAP) NmrA PF05368.8 EPS34470.1 - 6.3e-68 228.5 0.0 7.6e-68 228.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPS34470.1 - 0.00047 20.1 0.0 0.00069 19.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding DUF1876 PF08962.6 EPS34470.1 - 0.027 14.2 0.0 0.087 12.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1876) Inhibitor_I42 PF09394.5 EPS34471.1 - 0.11 12.8 0.0 0.13 12.6 0.0 1.1 1 0 0 1 1 1 0 Chagasin family peptidase inhibitor I42 Asparaginase PF00710.15 EPS34472.1 - 5e-102 340.9 0.0 6.2e-102 340.6 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Ank_2 PF12796.2 EPS34472.1 - 1.7e-14 53.8 0.2 3.6e-14 52.8 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EPS34472.1 - 2.5e-10 39.6 3.4 1.6e-05 24.4 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EPS34472.1 - 2.8e-10 40.4 1.1 1.2e-06 28.8 0.1 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPS34472.1 - 3.2e-10 39.9 1.6 1.7e-07 31.2 0.2 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPS34472.1 - 4e-06 26.5 3.3 0.0083 16.2 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat MTTB PF06253.6 EPS34472.1 - 0.016 12.9 1.0 0.023 12.4 0.7 1.1 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) Fungal_trans PF04082.13 EPS34473.1 - 2e-07 30.1 0.0 3.8e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain AAA_21 PF13304.1 EPS34473.1 - 0.16 11.9 0.4 8.7 6.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain LCCL PF03815.14 EPS34474.1 - 4.9e-24 84.1 0.0 7.5e-24 83.5 0.0 1.3 1 0 0 1 1 1 1 LCCL domain Aminotran_1_2 PF00155.16 EPS34475.1 - 1.7e-12 47.0 0.0 3e-09 36.3 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class I and II Tannase PF07519.6 EPS34475.1 - 0.012 14.2 0.0 0.021 13.5 0.0 1.2 1 0 0 1 1 1 0 Tannase and feruloyl esterase UPF0029 PF01205.14 EPS34476.1 - 3.1e-30 104.0 0.9 5.9e-30 103.1 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 RWD PF05773.17 EPS34476.1 - 2.8e-10 40.0 0.0 5.2e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 RWD domain Cytokin_check_N PF10407.4 EPS34476.1 - 0.043 13.4 0.0 0.088 12.4 0.0 1.4 1 0 0 1 1 1 0 Cdc14 phosphatase binding protein N-terminus UQ_con PF00179.21 EPS34476.1 - 0.11 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme Serglycin PF04360.7 EPS34477.1 - 0.031 13.9 0.3 0.065 12.9 0.2 1.5 1 0 0 1 1 1 0 Serglycin Glyco_hydro_61 PF03443.9 EPS34477.1 - 0.086 12.6 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 61 DUF3433 PF11915.3 EPS34478.1 - 2.1e-39 133.5 7.7 1.9e-23 82.4 1.0 3.4 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) Ribosomal_L4 PF00573.17 EPS34479.1 - 3.4e-42 144.0 0.6 5.4e-42 143.3 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EPS34479.1 - 2.7e-30 104.0 1.9 2.7e-30 104.0 1.3 1.9 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain COX6B PF02297.12 EPS34481.1 - 0.078 13.0 0.1 0.1 12.6 0.1 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb DUF4448 PF14610.1 EPS34482.1 - 4.5 6.7 6.2 4.9 6.5 4.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) FLO_LFY PF01698.11 EPS34482.1 - 5.1 5.8 10.8 5.3 5.7 7.5 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein Fungal_trans PF04082.13 EPS34484.1 - 5.9e-19 67.9 1.3 8.9e-19 67.3 0.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS34484.1 - 2.4e-07 30.5 12.8 5.3e-07 29.4 8.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3395 PF11875.3 EPS34485.1 - 2.6e-40 137.5 0.1 4.1e-40 136.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 EPS34485.1 - 2.4e-19 68.7 0.6 4.7e-19 67.8 0.4 1.5 1 0 0 1 1 1 1 DnaJ domain Lysine_decarbox PF03641.9 EPS34485.1 - 0.13 12.1 0.0 6.5 6.5 0.0 2.5 2 0 0 2 2 2 0 Possible lysine decarboxylase Acetone_carb_G PF08882.6 EPS34486.1 - 0.024 14.6 0.0 0.036 14.1 0.0 1.3 1 0 0 1 1 1 0 Acetone carboxylase gamma subunit SKIP_SNW PF02731.10 EPS34487.1 - 1.1e-67 226.4 6.2 1.1e-67 226.4 4.3 2.4 2 0 0 2 2 2 1 SKIP/SNW domain FAM60A PF15396.1 EPS34487.1 - 1.7 8.3 9.6 3.7 7.2 6.6 1.6 1 0 0 1 1 1 0 Protein Family FAM60A Nucleo_P87 PF07267.6 EPS34487.1 - 6.3 5.3 8.6 8.7 4.8 6.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF4603 PF15376.1 EPS34487.1 - 7.7 3.5 15.6 11 3.1 10.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) DUF1100 PF06500.6 EPS34488.1 - 4.3e-11 42.0 0.0 5.3e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_6 PF12697.2 EPS34488.1 - 8.3e-11 42.2 2.0 1.2e-10 41.6 0.4 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPS34488.1 - 9.8e-11 41.5 0.0 1.9e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EPS34488.1 - 2.9e-07 30.1 0.0 5.1e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 EPS34488.1 - 0.0001 21.5 0.0 0.00019 20.7 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 EPS34488.1 - 0.00036 20.0 0.1 0.0019 17.6 0.0 2.0 1 1 0 1 1 1 1 Putative esterase Epiglycanin_C PF14654.1 EPS34488.1 - 0.027 14.4 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region BAAT_C PF08840.6 EPS34488.1 - 0.039 13.6 0.0 0.073 12.7 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.15 EPS34488.1 - 0.068 12.7 0.4 26 4.2 0.1 3.1 2 1 1 3 3 3 0 alpha/beta hydrolase fold Cu-oxidase_3 PF07732.10 EPS34489.1 - 9.4e-39 131.7 2.3 9.4e-39 131.7 1.6 4.0 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EPS34489.1 - 3.3e-38 130.2 17.3 8.9e-37 125.6 1.2 3.6 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EPS34489.1 - 2.5e-36 124.9 5.1 4.4e-34 117.6 0.1 3.7 4 0 0 4 4 4 2 Multicopper oxidase ACT_7 PF13840.1 EPS34490.1 - 2.5e-23 81.3 0.4 1e-15 56.9 0.0 3.4 3 0 0 3 3 3 3 ACT domain WD40 PF00400.27 EPS34491.1 - 1.1e-31 107.5 16.7 2.6e-07 30.2 0.3 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat VID27 PF08553.5 EPS34491.1 - 0.0033 15.7 0.0 0.0041 15.4 0.0 1.1 1 0 0 1 1 1 1 VID27 cytoplasmic protein Coatomer_WDAD PF04053.9 EPS34491.1 - 0.16 10.7 0.2 1.1 8.0 0.0 2.2 2 1 1 3 3 3 0 Coatomer WD associated region Septin PF00735.13 EPS34492.1 - 9.3e-116 385.7 0.2 1.4e-115 385.1 0.1 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EPS34492.1 - 4.8e-07 29.7 0.0 9.1e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EPS34492.1 - 1.2e-06 28.1 0.3 2e-05 24.0 0.2 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EPS34492.1 - 1.1e-05 24.6 0.0 2.6e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EPS34492.1 - 0.0012 18.9 0.1 0.0041 17.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EPS34492.1 - 0.0033 17.0 0.0 0.0061 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 EPS34492.1 - 0.0052 17.2 0.1 0.016 15.6 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 EPS34492.1 - 0.0058 15.7 0.0 0.012 14.6 0.0 1.6 1 0 0 1 1 1 1 AIG1 family FtsK_SpoIIIE PF01580.13 EPS34492.1 - 0.0085 15.5 0.1 0.019 14.4 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family IIGP PF05049.8 EPS34492.1 - 0.0091 14.8 0.0 0.015 14.1 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Pox_A32 PF04665.7 EPS34492.1 - 0.014 14.7 0.1 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein Ras PF00071.17 EPS34492.1 - 0.036 13.4 0.6 0.11 11.8 0.3 1.9 2 1 0 2 2 2 0 Ras family NACHT PF05729.7 EPS34492.1 - 0.043 13.4 0.0 0.076 12.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 EPS34492.1 - 0.05 13.9 0.1 0.17 12.2 0.0 1.9 2 0 0 2 2 2 0 ABC transporter PduV-EutP PF10662.4 EPS34492.1 - 0.056 12.9 0.3 2.8 7.4 0.2 2.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 EPS34492.1 - 0.061 13.1 5.7 0.94 9.2 0.1 2.9 2 1 1 3 3 3 0 Dynamin family Arch_ATPase PF01637.13 EPS34492.1 - 0.062 12.9 0.1 0.062 12.9 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase Sigma54_activat PF00158.21 EPS34492.1 - 0.075 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.1 EPS34492.1 - 0.079 12.9 0.3 0.25 11.3 0.0 2.1 2 1 0 2 2 2 0 AAA ATPase domain ATP_bind_1 PF03029.12 EPS34492.1 - 0.085 12.3 0.8 9.2 5.7 0.1 2.7 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein KAP_NTPase PF07693.9 EPS34492.1 - 0.21 10.5 3.2 0.48 9.3 2.2 1.7 1 1 0 1 1 1 0 KAP family P-loop domain Myc-LZ PF02344.10 EPS34492.1 - 0.33 10.6 4.1 0.95 9.1 0.3 2.6 2 0 0 2 2 2 0 Myc leucine zipper domain AAA_23 PF13476.1 EPS34492.1 - 4.1 7.6 15.5 1.4e+02 2.6 10.7 2.1 1 1 0 1 1 1 0 AAA domain WD40 PF00400.27 EPS34493.1 - 5e-55 181.5 20.3 1e-11 44.2 0.1 12.8 13 0 0 13 13 13 10 WD domain, G-beta repeat Utp12 PF04003.7 EPS34493.1 - 3.4e-30 104.1 0.0 5.1e-30 103.6 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 EPS34493.1 - 1.5e-09 37.8 2.9 0.038 13.7 0.1 6.8 6 1 1 7 7 7 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EPS34493.1 - 4.2e-07 28.4 8.3 0.45 8.5 0.0 5.4 3 1 0 5 5 5 4 Nucleoporin Nup120/160 Gmad1 PF10647.4 EPS34493.1 - 8.8e-06 25.2 0.0 0.00052 19.4 0.0 2.9 2 1 1 3 3 3 1 Lipoprotein LpqB beta-propeller domain Nbas_N PF15492.1 EPS34493.1 - 0.001 18.2 0.3 0.71 8.9 0.0 3.4 3 1 0 3 3 3 2 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.7 EPS34493.1 - 0.047 11.5 0.0 6.4 4.4 0.1 3.0 2 1 0 2 2 2 0 IKI3 family PQQ_3 PF13570.1 EPS34493.1 - 0.051 13.8 6.6 1.1 9.5 0.3 5.4 5 1 0 5 5 5 0 PQQ-like domain DPPIV_N PF00930.16 EPS34493.1 - 0.091 11.3 0.0 14 4.1 0.0 2.7 2 1 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Coatomer_WDAD PF04053.9 EPS34493.1 - 0.15 10.8 0.1 1.1 8.0 0.0 2.4 4 0 0 4 4 4 0 Coatomer WD associated region p450 PF00067.17 EPS34494.1 - 1.3e-30 106.3 0.0 3.4e-30 104.9 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 XRN_N PF03159.13 EPS34495.1 - 3e-101 337.7 0.0 3e-101 337.7 0.0 1.6 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus DUF830 PF05708.7 EPS34495.1 - 0.12 12.3 0.3 0.36 10.8 0.2 1.7 1 0 0 1 1 1 0 Orthopoxvirus protein of unknown function (DUF830) FXR1P_C PF12235.3 EPS34495.1 - 0.19 11.8 10.7 0.36 10.9 7.4 1.5 1 0 0 1 1 1 0 Fragile X-related 1 protein C terminal WD40 PF00400.27 EPS34496.1 - 2.3e-43 144.5 6.5 8.4e-10 38.1 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EPS34496.1 - 1.4e-29 101.7 0.3 3e-29 100.7 0.2 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Nup160 PF11715.3 EPS34496.1 - 0.00042 18.5 1.4 0.59 8.2 0.0 3.5 2 1 0 4 4 4 2 Nucleoporin Nup120/160 GTP_cyclohydroI PF01227.17 EPS34497.1 - 2.6e-73 245.1 0.2 3.9e-73 244.5 0.2 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 EPS34497.1 - 0.0055 16.6 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein Pkinase PF00069.20 EPS34498.1 - 1.1e-68 231.2 0.0 1.6e-68 230.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS34498.1 - 5.5e-35 120.6 0.0 2.2e-34 118.6 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPS34498.1 - 0.0041 16.1 0.0 0.018 13.9 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 EPS34498.1 - 0.037 13.0 0.3 0.13 11.3 0.2 1.8 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IF4E PF01652.13 EPS34500.1 - 1.3e-52 177.7 0.0 1.8e-52 177.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Peptidase_C48 PF02902.14 EPS34501.1 - 1.5e-31 109.7 0.0 7.2e-31 107.4 0.0 2.1 2 1 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain AIG2 PF06094.7 EPS34502.1 - 1.7e-13 50.9 0.1 2.3e-13 50.4 0.1 1.2 1 0 0 1 1 1 1 AIG2-like family SPC22 PF04573.7 EPS34503.1 - 1.2e-34 119.1 0.0 4.9e-24 84.4 0.0 2.1 2 0 0 2 2 2 2 Signal peptidase subunit Pmp3 PF01679.12 EPS34504.1 - 3.5e-23 81.0 8.1 4.4e-23 80.7 5.6 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator SNARE_assoc PF09335.6 EPS34504.1 - 0.07 13.3 0.0 0.088 13.0 0.0 1.2 1 0 0 1 1 1 0 SNARE associated Golgi protein DUF3165 PF11364.3 EPS34504.1 - 0.081 13.0 0.5 0.12 12.5 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3165) BCDHK_Adom3 PF10436.4 EPS34505.1 - 6.1e-47 159.1 0.1 1.5e-46 157.9 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EPS34505.1 - 2.8e-10 39.8 0.0 4.6e-09 35.9 0.0 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 EPS34505.1 - 0.0005 19.8 0.0 0.093 12.5 0.0 2.4 1 1 1 2 2 2 2 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.1 EPS34505.1 - 0.014 15.0 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase USP7_ICP0_bdg PF12436.3 EPS34506.1 - 4.5e-88 294.6 0.7 1.9e-86 289.3 0.2 2.3 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 EPS34506.1 - 5.4e-69 231.8 4.2 2.5e-67 226.4 0.0 3.7 3 1 1 4 4 4 1 Ubiquitin-specific protease C-terminal UCH PF00443.24 EPS34506.1 - 1.5e-54 184.8 0.2 2.5e-54 184.2 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EPS34506.1 - 1.9e-30 106.3 0.0 4.2e-30 105.1 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 EPS34506.1 - 4.8e-09 36.4 0.1 2.7e-08 34.0 0.0 2.3 2 0 0 2 2 2 1 MATH domain Rad60-SLD PF11976.3 EPS34506.1 - 0.0011 18.5 4.5 2.6 7.7 0.1 4.6 4 1 0 4 4 4 2 Ubiquitin-2 like Rad60 SUMO-like EMP24_GP25L PF01105.19 EPS34507.1 - 4.6e-48 163.3 3.8 5.3e-48 163.1 2.6 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF2012 PF09430.5 EPS34507.1 - 0.024 14.4 0.3 0.058 13.2 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2012) Hydrophobin PF01185.13 EPS34510.1 - 3.7e-05 24.0 2.5 5.1e-05 23.6 1.7 1.3 1 0 0 1 1 1 1 Fungal hydrophobin Fungal_trans_2 PF11951.3 EPS34511.1 - 6.9e-11 41.3 0.7 1.2e-10 40.5 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS34511.1 - 3.3e-09 36.4 9.8 5.8e-09 35.7 6.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CTD_bind PF04818.8 EPS34513.1 - 0.00017 21.7 0.0 0.0004 20.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Glyco_hydro_11 PF00457.12 EPS34514.1 - 1.4e-44 151.5 7.7 1.8e-44 151.2 5.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 DUF4620 PF15399.1 EPS34517.1 - 0.19 11.8 0.9 0.29 11.2 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4620) Helicase_C_3 PF13625.1 EPS34518.1 - 1.1e-27 96.3 0.0 2.7e-27 95.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPS34518.1 - 1.1e-15 57.9 0.0 2.2e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EPS34518.1 - 1.5e-11 44.0 0.0 3e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EPS34518.1 - 2.3e-11 43.0 0.0 3.7e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 EPS34518.1 - 3.4e-06 26.6 0.1 7.9e-06 25.4 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_34 PF13872.1 EPS34518.1 - 0.011 14.4 0.0 0.018 13.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 DUF4243 PF14027.1 EPS34520.1 - 2.9e-101 339.2 0.1 3.6e-101 338.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) CN_hydrolase PF00795.17 EPS34522.1 - 9e-30 103.4 0.0 1.4e-29 102.7 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 EPS34522.1 - 1.1e-21 76.9 0.0 5.8e-21 74.4 0.0 2.0 1 1 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.11 EPS34522.1 - 0.12 10.9 0.1 0.21 10.1 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase NUDIX-like PF09296.6 EPS34523.1 - 6.9e-21 74.4 0.0 1.6e-20 73.2 0.0 1.7 1 0 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain NUDIX PF00293.23 EPS34523.1 - 1.7e-16 60.0 0.1 3.3e-16 59.1 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.6 EPS34523.1 - 9.7e-06 25.0 2.0 1.8e-05 24.1 1.4 1.5 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Zn_Tnp_IS91 PF14319.1 EPS34523.1 - 0.2 11.1 1.2 1.5 8.3 0.2 2.4 2 1 1 3 3 3 0 Transposase zinc-binding domain POT1 PF02765.12 EPS34524.1 - 3.5e-10 39.9 0.0 6.6e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 FMO-like PF00743.14 EPS34525.1 - 7.1e-41 139.9 0.0 4.3e-26 91.2 0.0 3.0 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EPS34525.1 - 2e-18 67.1 0.0 4.7e-17 62.7 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EPS34525.1 - 5.7e-12 45.2 0.2 3.1e-09 36.2 0.0 2.8 2 1 1 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EPS34525.1 - 5e-11 42.6 0.0 4.1e-10 39.6 0.0 2.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EPS34525.1 - 5.3e-08 32.9 0.0 2.8e-07 30.6 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPS34525.1 - 2.8e-05 24.0 0.1 7.6e-05 22.6 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EPS34525.1 - 5e-05 22.5 0.3 0.0011 18.1 0.1 2.1 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 EPS34525.1 - 0.0012 17.8 0.2 0.62 8.8 0.1 2.9 2 1 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EPS34525.1 - 0.036 12.5 0.1 0.45 8.9 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.19 EPS34525.1 - 0.082 11.7 0.0 3.4 6.4 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain HDA2-3 PF11496.3 EPS34526.1 - 1.2e-35 122.8 0.0 5.7e-35 120.5 0.0 2.2 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DASH_Dam1 PF08653.5 EPS34526.1 - 0.15 11.8 0.6 0.71 9.6 0.2 2.4 2 0 0 2 2 2 0 DASH complex subunit Dam1 CENP-F_leu_zip PF10473.4 EPS34526.1 - 0.17 11.7 49.1 0.74 9.6 11.8 3.5 2 2 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.16 EPS34526.1 - 0.79 9.1 37.9 2.9 7.2 26.3 1.9 1 1 0 1 1 1 0 Intermediate filament protein DUF2968 PF11180.3 EPS34526.1 - 3.7 6.9 35.6 0.12 11.7 7.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2968) CALCOCO1 PF07888.6 EPS34526.1 - 3.8 5.6 29.5 6.2 4.9 20.5 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Reo_sigmaC PF04582.7 EPS34526.1 - 7.2 5.6 6.6 1.7 7.7 0.7 2.3 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Nup54 PF13874.1 EPS34526.1 - 9.1 5.9 27.8 0.73 9.4 8.4 2.9 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 ketoacyl-synt PF00109.21 EPS34527.1 - 8.3e-78 261.3 0.0 1.6e-77 260.4 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EPS34527.1 - 8.6e-53 179.7 0.0 1.9e-52 178.5 0.0 1.6 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EPS34527.1 - 7.5e-34 116.1 0.1 1.7e-33 114.9 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 EPS34527.1 - 1e-23 84.8 0.0 3e-23 83.2 0.0 1.9 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 EPS34527.1 - 3.4e-23 81.6 5.2 1.5e-11 44.3 0.5 2.7 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.1 EPS34527.1 - 4.8e-16 58.7 0.0 7.5e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.18 EPS34527.1 - 6.5e-05 22.0 0.0 0.00015 20.8 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Abhydrolase_5 PF12695.2 EPS34527.1 - 0.00017 21.3 0.0 0.15 11.8 0.0 2.8 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EPS34527.1 - 0.0006 19.7 0.0 0.033 14.0 0.0 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Cu-oxidase_3 PF07732.10 EPS34528.1 - 2.2e-42 143.4 0.7 5.2e-42 142.3 0.5 1.6 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EPS34528.1 - 1.2e-26 92.8 8.6 1.9e-21 76.0 0.5 3.6 3 0 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.17 EPS34528.1 - 1.5e-22 80.1 0.0 2e-21 76.5 0.0 2.3 2 0 0 2 2 2 1 Multicopper oxidase Transglut_core PF01841.14 EPS34530.1 - 3.3e-09 36.9 0.0 7.4e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.12 EPS34530.1 - 2.2e-08 33.4 0.1 5.9e-08 32.0 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EPS34530.1 - 2.5e-07 29.9 0.8 1.4e-06 27.5 0.0 2.5 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EPS34530.1 - 1.6e-05 24.3 0.9 4.7e-05 22.8 0.1 2.2 2 0 0 2 2 2 1 Variant SH3 domain DHHA2 PF02833.9 EPS34531.1 - 1.8e-15 57.2 0.1 3.2e-15 56.4 0.1 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 EPS34531.1 - 0.00043 19.9 0.1 0.004 16.7 0.1 2.3 1 1 0 1 1 1 1 DHH family adh_short PF00106.20 EPS34532.1 - 1e-13 51.5 1.4 1.4e-13 51.0 0.2 1.7 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EPS34532.1 - 1.8e-06 28.0 0.1 4e-06 26.9 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EPS34532.1 - 2.4e-06 27.1 0.0 3.2e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EPS34532.1 - 6.6e-05 22.6 1.0 0.00011 21.9 0.1 1.7 2 0 0 2 2 2 1 KR domain NmrA PF05368.8 EPS34532.1 - 0.075 12.2 0.2 0.7 9.1 0.0 2.0 2 0 0 2 2 2 0 NmrA-like family PALP PF00291.20 EPS34533.1 - 2e-26 92.9 0.0 2.8e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PLU-1 PF08429.6 EPS34534.1 - 4.5e-100 334.8 20.6 2e-98 329.3 13.6 2.2 2 0 0 2 2 2 1 PLU-1-like protein JmjC PF02373.17 EPS34534.1 - 1.3e-42 144.6 0.1 3e-42 143.4 0.1 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.16 EPS34534.1 - 1.4e-25 88.9 0.0 4.5e-25 87.3 0.0 2.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.12 EPS34534.1 - 1e-17 63.3 1.2 2.8e-17 61.9 0.9 1.8 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.11 EPS34534.1 - 1.6e-17 63.2 6.5 4.4e-17 61.8 4.5 1.8 1 0 0 1 1 1 1 C5HC2 zinc finger PHD PF00628.24 EPS34534.1 - 1.4e-16 59.9 33.1 1.1e-08 34.5 5.7 3.5 3 0 0 3 3 3 3 PHD-finger PHD_2 PF13831.1 EPS34534.1 - 0.00042 19.5 3.1 0.00042 19.5 2.1 3.0 3 0 0 3 3 3 1 PHD-finger zf-PHD-like PF15446.1 EPS34534.1 - 0.15 11.3 14.5 0.037 13.3 0.9 2.7 3 0 0 3 3 3 0 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 EPS34534.1 - 0.64 9.8 21.5 0.11 12.2 0.4 3.4 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) GIY-YIG PF01541.19 EPS34535.1 - 7e-07 29.5 0.0 1.5e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 GIY-YIG catalytic domain FANCL_C PF11793.3 EPS34535.1 - 1.8e-05 24.5 3.8 3.2e-05 23.7 2.6 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-HC5HC2H PF13771.1 EPS34535.1 - 0.0015 18.6 2.2 0.003 17.6 1.5 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain Prok-RING_1 PF14446.1 EPS34535.1 - 0.0018 17.9 1.0 0.0018 17.9 0.7 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-HC5HC2H_2 PF13832.1 EPS34535.1 - 0.0049 16.8 1.5 0.0089 16.0 1.1 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain Guanylate_cyc_2 PF09778.4 EPS34535.1 - 0.12 11.5 0.1 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Guanylylate cyclase Thymidylate_kin PF02223.12 EPS34536.1 - 1.5e-45 154.8 0.0 1.8e-45 154.6 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.5 EPS34536.1 - 0.0017 17.6 0.0 0.0089 15.2 0.0 2.0 2 1 0 2 2 2 1 Chromatin associated protein KTI12 CPT PF07931.7 EPS34536.1 - 0.053 13.1 0.0 0.084 12.4 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein TGT PF01702.13 EPS34537.1 - 3.3e-40 137.8 0.0 4.1e-40 137.5 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase MTHFR PF02219.12 EPS34538.1 - 5e-97 324.4 0.0 7.2e-97 323.9 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase FLILHELTA PF10306.4 EPS34539.1 - 3.5e-27 94.2 0.0 5.7e-27 93.5 0.0 1.3 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.8 EPS34539.1 - 0.0014 18.8 0.0 0.0023 18.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) NDK PF00334.14 EPS34540.1 - 2.7e-55 185.8 0.0 3.1e-55 185.6 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Glyco_hydro_31 PF01055.21 EPS34541.1 - 1.3e-145 485.5 4.9 1.7e-145 485.2 3.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EPS34541.1 - 3.9e-25 87.4 0.2 1.1e-24 86.0 0.2 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like PQ-loop PF04193.9 EPS34542.1 - 4.9e-23 80.4 2.0 5.5e-14 51.4 0.1 2.6 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.13 EPS34542.1 - 0.0033 17.9 0.7 0.012 16.1 0.4 2.0 1 1 0 1 1 1 1 ER lumen protein retaining receptor NMT1 PF09084.6 EPS34543.1 - 0.0021 17.7 0.0 0.0098 15.4 0.0 2.1 2 1 0 2 2 2 1 NMT1/THI5 like Glyco_hydro_18 PF00704.23 EPS34544.1 - 1.7e-18 67.1 5.5 2.2e-18 66.8 2.4 2.1 1 1 1 2 2 2 1 Glycosyl hydrolases family 18 E1-E2_ATPase PF00122.15 EPS34545.1 - 4.2e-73 245.1 0.1 4e-72 241.9 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EPS34545.1 - 1.1e-24 88.0 0.3 3.2e-24 86.5 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EPS34545.1 - 1e-14 55.1 0.0 2e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EPS34545.1 - 2.2e-09 36.6 0.0 5.2e-09 35.4 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EPS34545.1 - 0.00097 18.7 0.0 0.017 14.7 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EPS34545.1 - 0.026 14.4 0.0 0.062 13.2 0.0 1.6 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit tRNA-synt_1c PF00749.16 EPS34546.1 - 1.4e-100 336.0 0.0 1.8e-100 335.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EPS34546.1 - 8.8e-41 139.4 0.2 2.2e-40 138.1 0.2 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 EPS34546.1 - 1.3e-08 35.1 0.1 3.6e-08 33.7 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EPS34546.1 - 0.012 15.5 0.2 0.041 13.7 0.1 2.0 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EPS34546.1 - 0.013 15.5 0.0 0.033 14.1 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.14 EPS34546.1 - 0.052 12.6 0.3 0.14 11.2 0.1 1.5 1 1 1 2 2 2 0 tRNA synthetases class I (C) catalytic domain Ribosomal_L1 PF00687.16 EPS34547.1 - 3.9e-31 108.1 0.0 4.6e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family COG2 PF06148.6 EPS34548.1 - 2.2e-34 118.2 1.0 3.5e-34 117.5 0.7 1.3 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 EPS34548.1 - 1.3e-06 28.1 0.3 5.8e-06 26.0 0.1 2.2 2 1 1 3 3 3 1 Vps51/Vps67 DUF2450 PF10475.4 EPS34548.1 - 0.019 13.9 0.1 0.033 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) Prominin PF05478.6 EPS34548.1 - 0.052 11.0 0.1 0.087 10.3 0.0 1.3 1 0 0 1 1 1 0 Prominin DUF3287 PF11690.3 EPS34548.1 - 0.067 13.2 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) Spc7 PF08317.6 EPS34548.1 - 0.13 10.9 0.9 0.18 10.4 0.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.9 EPS34548.1 - 0.31 10.5 5.5 0.54 9.8 3.8 1.4 1 0 0 1 1 1 0 IncA protein Zwint PF15556.1 EPS34548.1 - 0.4 9.9 6.8 0.34 10.1 1.0 2.1 1 1 0 2 2 2 0 ZW10 interactor FlaC_arch PF05377.6 EPS34548.1 - 1.3 8.9 4.3 11 5.9 0.1 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) ParA PF10609.4 EPS34550.1 - 6.5e-34 115.6 0.1 1.6e-33 114.3 0.0 1.7 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EPS34550.1 - 5.9e-14 51.9 0.0 9.6e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 EPS34550.1 - 4.2e-07 29.3 0.0 9.8e-06 24.8 0.0 2.1 1 1 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.1 EPS34550.1 - 7.2e-06 26.0 0.1 4.3e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 EPS34550.1 - 0.0001 21.4 1.2 0.00023 20.3 0.9 1.5 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_25 PF13481.1 EPS34550.1 - 0.0005 19.5 0.1 0.00086 18.7 0.1 1.3 1 0 0 1 1 1 1 AAA domain YhjQ PF06564.7 EPS34550.1 - 0.0029 16.9 2.4 0.026 13.9 1.2 2.4 1 1 1 2 2 2 1 YhjQ protein AAA_26 PF13500.1 EPS34550.1 - 0.0079 15.8 1.5 0.62 9.6 0.5 2.3 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 EPS34550.1 - 0.0082 14.9 0.4 0.012 14.4 0.3 1.2 1 0 0 1 1 1 1 ArgK protein Nucleoplasmin PF03066.10 EPS34550.1 - 0.026 14.0 0.1 0.034 13.6 0.1 1.2 1 0 0 1 1 1 0 Nucleoplasmin APS_kinase PF01583.15 EPS34550.1 - 0.09 12.4 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase UIM PF02809.15 EPS34550.1 - 0.16 11.5 0.3 0.16 11.5 0.2 2.9 2 1 1 3 3 3 0 Ubiquitin interaction motif DUF258 PF03193.11 EPS34550.1 - 0.24 10.5 1.3 0.37 9.9 0.5 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 SEP PF08059.8 EPS34551.1 - 4.2e-28 97.4 0.1 9.2e-28 96.3 0.0 1.6 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 EPS34551.1 - 9.6e-16 57.6 0.0 1.7e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 EPS34551.1 - 1.3e-13 50.2 0.2 2.1e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 UBA-like domain UBA PF00627.26 EPS34551.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 0 UBA/TS-N domain TOM13 PF08219.6 EPS34552.1 - 7.3e-29 99.3 0.0 1e-28 98.9 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 60KD_IMP PF02096.15 EPS34553.1 - 1.3e-32 113.1 0.1 3.4e-32 111.7 0.1 1.7 1 0 0 1 1 1 1 60Kd inner membrane protein TAFII28 PF04719.9 EPS34554.1 - 3.7e-19 68.2 0.0 7.4e-19 67.3 0.0 1.4 1 0 0 1 1 1 1 hTAFII28-like protein conserved region DUF605 PF04652.11 EPS34554.1 - 0.0013 18.1 10.8 0.0013 18.1 7.5 1.7 2 0 0 2 2 2 1 Vta1 like SRP-alpha_N PF04086.8 EPS34554.1 - 0.41 9.9 6.3 0.05 12.9 1.1 1.7 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal KAR9 PF08580.5 EPS34554.1 - 1.1 7.4 8.6 1.4 7.1 6.0 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 SAM_decarbox PF01536.11 EPS34555.1 - 2.7e-87 292.5 0.0 6.8e-86 287.9 0.0 2.5 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase DUF1546 PF07571.8 EPS34556.1 - 1.1e-34 118.3 0.0 3.3e-34 116.8 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 EPS34556.1 - 5.5e-26 90.3 0.0 2.4e-25 88.2 0.0 2.0 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 EPS34556.1 - 7e-07 29.2 0.1 6.3e-06 26.2 0.1 2.2 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EPS34556.1 - 0.019 15.0 0.2 0.26 11.3 0.0 2.5 3 0 0 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Plant_NMP1 PF06694.6 EPS34556.1 - 0.034 13.0 0.0 0.092 11.6 0.0 1.6 1 1 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) CRAL_TRIO PF00650.15 EPS34557.1 - 6.6e-18 64.7 0.0 1.2e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EPS34557.1 - 8.1e-07 29.0 0.0 2.2e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Prok_Ub PF14454.1 EPS34557.1 - 0.062 12.9 0.0 0.54 9.9 0.0 2.3 2 0 0 2 2 2 0 Prokaryotic Ubiquitin IPP-2 PF04979.9 EPS34558.1 - 2.4e-12 47.2 19.1 4e-07 30.3 1.3 2.4 1 1 2 3 3 3 2 Protein phosphatase inhibitor 2 (IPP-2) CAF1A PF12253.3 EPS34561.1 - 5.3e-24 84.1 6.9 5.3e-24 84.1 4.8 3.5 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 EPS34561.1 - 0.00058 19.3 77.9 0.0017 17.7 53.9 2.0 1 1 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Mem_trans PF03547.13 EPS34561.1 - 0.23 9.6 1.5 0.35 9.1 1.1 1.2 1 0 0 1 1 1 0 Membrane transport protein Hex_IIIa PF02455.11 EPS34561.1 - 5.9 5.4 11.8 10 4.6 8.2 1.6 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Borrelia_P83 PF05262.6 EPS34561.1 - 7.1 4.7 35.7 12 4.0 24.7 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein CoA_transf_3 PF02515.12 EPS34567.1 - 7.8e-51 172.0 0.0 1.1e-50 171.5 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Glyco_hydro_18 PF00704.23 EPS34568.1 - 1.8e-19 70.4 0.2 3e-19 69.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Sugar_tr PF00083.19 EPS34570.1 - 3.3e-78 263.2 28.2 3.9e-78 263.0 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS34570.1 - 2.6e-25 88.9 50.8 2.6e-20 72.4 14.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EPS34570.1 - 6e-07 28.0 1.9 6e-07 28.0 1.3 2.4 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF2613 PF11021.3 EPS34570.1 - 0.13 11.9 0.1 0.54 9.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2613) Glyco_hydro_1 PF00232.13 EPS34571.1 - 7.1e-151 502.4 0.1 8.2e-151 502.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_cc PF11790.3 EPS34571.1 - 1.9e-05 24.2 0.0 3.4e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Fungal_trans PF04082.13 EPS34572.1 - 4.4e-12 45.4 1.9 1.1e-09 37.6 0.0 2.4 3 0 0 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS34572.1 - 6.6e-06 25.9 10.5 1.1e-05 25.2 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HCV_env PF01539.12 EPS34575.1 - 0.1 12.0 0.8 0.7 9.3 0.6 2.0 1 1 0 1 1 1 0 Hepatitis C virus envelope glycoprotein E1 DUF869 PF05911.6 EPS34576.1 - 1.2e-05 23.8 26.4 1.2e-05 23.8 18.3 3.2 2 1 1 3 3 3 2 Plant protein of unknown function (DUF869) ATG16 PF08614.6 EPS34576.1 - 0.0002 21.2 21.3 0.0002 21.2 14.8 4.6 2 2 1 4 4 4 1 Autophagy protein 16 (ATG16) IncA PF04156.9 EPS34576.1 - 0.0009 18.8 7.4 0.0009 18.8 5.1 5.4 3 1 1 4 4 4 2 IncA protein SlyX PF04102.7 EPS34576.1 - 0.0082 16.5 0.0 0.0082 16.5 0.0 9.5 5 2 3 9 9 9 1 SlyX DivIC PF04977.10 EPS34576.1 - 0.0096 15.3 5.6 0.0096 15.3 3.9 9.6 4 2 5 9 9 9 2 Septum formation initiator DUF1192 PF06698.6 EPS34576.1 - 0.15 11.9 0.1 0.15 11.9 0.1 9.1 8 1 1 10 10 10 0 Protein of unknown function (DUF1192) Cep57_CLD_2 PF14197.1 EPS34576.1 - 0.17 11.8 0.1 0.17 11.8 0.1 8.4 8 3 0 8 8 8 0 Centrosome localisation domain of PPC89 GAS PF13851.1 EPS34576.1 - 0.6 9.2 68.8 0.073 12.2 1.8 4.3 3 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding AAA_27 PF13514.1 EPS34576.1 - 1.1 6.8 84.1 0.024 12.3 33.1 2.3 2 0 0 2 2 2 0 AAA domain KGG PF10685.4 EPS34577.1 - 6.1e-07 29.2 0.4 6.1e-07 29.2 0.3 2.3 2 0 0 2 2 2 1 Stress-induced bacterial acidophilic repeat motif Glyco_hydro_18 PF00704.23 EPS34578.1 - 5.8e-06 25.9 0.0 1.1e-05 25.1 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 DUF4262 PF14081.1 EPS34578.1 - 0.12 12.5 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4262) PhoD PF09423.5 EPS34579.1 - 2.1e-59 201.2 0.0 3.2e-59 200.6 0.0 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase fn3 PF00041.16 EPS34579.1 - 0.045 13.8 0.4 0.13 12.3 0.3 1.8 1 0 0 1 1 1 0 Fibronectin type III domain SRP54 PF00448.17 EPS34580.1 - 1e-74 250.2 2.8 1.5e-74 249.7 1.5 1.6 2 0 0 2 2 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EPS34580.1 - 1.4e-24 86.3 1.1 1.4e-24 86.3 0.8 4.2 4 1 1 5 5 3 1 Signal peptide binding domain SRP54_N PF02881.14 EPS34580.1 - 2.4e-17 62.7 1.2 6e-17 61.5 0.8 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 EPS34580.1 - 5.4e-10 38.9 0.2 1.7e-09 37.4 0.1 1.8 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EPS34580.1 - 1.9e-07 31.0 0.3 2.1e-06 27.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EPS34580.1 - 2.9e-05 24.8 0.0 7.7e-05 23.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 EPS34580.1 - 3.4e-05 23.5 0.2 9.8e-05 22.0 0.1 1.8 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_31 PF13614.1 EPS34580.1 - 8.5e-05 22.5 0.0 0.12 12.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain CbiA PF01656.18 EPS34580.1 - 9.1e-05 21.9 0.5 0.00032 20.1 0.3 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.7 EPS34580.1 - 0.00045 19.3 0.1 0.00094 18.3 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin APS_kinase PF01583.15 EPS34580.1 - 0.00053 19.6 0.0 0.0012 18.5 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase ArgK PF03308.11 EPS34580.1 - 0.00083 18.2 0.1 0.00083 18.2 0.1 2.8 2 2 1 3 3 3 1 ArgK protein AAA_16 PF13191.1 EPS34580.1 - 0.0013 18.8 0.1 0.004 17.1 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain ATP_bind_1 PF03029.12 EPS34580.1 - 0.0027 17.2 0.8 0.014 14.9 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 EPS34580.1 - 0.0031 17.6 0.0 0.01 15.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain 6PF2K PF01591.13 EPS34580.1 - 0.0039 16.2 0.0 0.0072 15.4 0.0 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase SRPRB PF09439.5 EPS34580.1 - 0.0047 16.1 0.8 1.5 8.0 0.1 3.3 2 1 1 3 3 3 1 Signal recognition particle receptor beta subunit Thymidylate_kin PF02223.12 EPS34580.1 - 0.0071 15.7 0.1 0.021 14.1 0.1 1.8 1 0 0 1 1 1 1 Thymidylate kinase AAA_18 PF13238.1 EPS34580.1 - 0.011 16.0 0.0 0.025 14.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EPS34580.1 - 0.015 15.2 0.6 0.029 14.3 0.1 1.8 2 0 0 2 2 2 0 AAA domain VirE PF05272.6 EPS34580.1 - 0.046 13.1 0.0 0.096 12.1 0.0 1.5 1 0 0 1 1 1 0 Virulence-associated protein E Arf PF00025.16 EPS34580.1 - 0.058 12.6 0.1 0.23 10.6 0.0 2.0 3 0 0 3 3 3 0 ADP-ribosylation factor family AAA_25 PF13481.1 EPS34580.1 - 0.072 12.4 0.2 0.26 10.6 0.1 2.0 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EPS34580.1 - 0.098 12.9 1.1 0.32 11.2 0.1 2.4 2 1 0 2 2 2 0 ABC transporter Rrp15p PF07890.7 EPS34581.1 - 4.5e-36 123.7 7.2 4.5e-36 123.7 5.0 2.0 2 1 0 2 2 2 1 Rrp15p Fer2 PF00111.22 EPS34582.1 - 1.2e-14 53.7 0.8 1.6e-14 53.3 0.6 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Flagellin_IN PF07196.8 EPS34582.1 - 0.15 12.0 0.3 0.25 11.3 0.2 1.3 1 0 0 1 1 1 0 Flagellin hook IN motif Mito_carr PF00153.22 EPS34583.1 - 2e-13 49.8 0.0 0.034 13.8 0.0 5.4 5 1 0 5 5 5 5 Mitochondrial carrier protein Hap4_Hap_bind PF10297.4 EPS34584.1 - 5.2e-09 35.6 7.1 5.2e-09 35.6 4.9 2.4 2 0 0 2 2 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.16 EPS34584.1 - 9.6e-09 35.0 14.6 8.9e-06 25.5 6.0 2.6 1 1 1 2 2 2 2 bZIP transcription factor DUF2408 PF10303.4 EPS34584.1 - 0.00059 19.9 0.5 0.0011 19.0 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2408) DUF812 PF05667.6 EPS34584.1 - 0.017 13.6 3.3 0.026 13.0 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF3450 PF11932.3 EPS34584.1 - 0.041 13.1 6.2 0.082 12.1 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) FlaC_arch PF05377.6 EPS34584.1 - 0.082 12.8 0.8 0.16 11.8 0.5 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Phage_int_SAM_5 PF13102.1 EPS34584.1 - 0.085 12.8 1.4 0.15 12.0 1.0 1.3 1 0 0 1 1 1 0 Phage integrase SAM-like domain Spc7 PF08317.6 EPS34584.1 - 0.11 11.0 5.0 0.17 10.5 3.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Filament PF00038.16 EPS34584.1 - 0.2 11.0 8.8 0.32 10.4 6.1 1.2 1 0 0 1 1 1 0 Intermediate filament protein Kinetocho_Slk19 PF12709.2 EPS34584.1 - 0.49 10.5 4.3 1.1 9.3 2.9 1.6 1 0 0 1 1 1 0 Central kinetochore-associated Phlebovirus_NSM PF07246.6 EPS34584.1 - 0.5 9.4 3.6 0.92 8.6 2.5 1.4 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M ScpA_ScpB PF02616.9 EPS34584.1 - 0.56 9.7 5.5 0.84 9.1 3.8 1.1 1 0 0 1 1 1 0 ScpA/B protein Mnd1 PF03962.10 EPS34584.1 - 0.8 9.3 5.7 1.7 8.3 4.0 1.4 1 0 0 1 1 1 0 Mnd1 family AAA_13 PF13166.1 EPS34584.1 - 0.82 8.0 6.0 1.3 7.4 4.2 1.1 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.3 EPS34584.1 - 0.84 6.8 8.6 1.2 6.3 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FUSC PF04632.7 EPS34584.1 - 2.4 6.4 5.6 3.7 5.8 3.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Herpes_capsid PF06112.6 EPS34584.1 - 8 6.4 8.4 25 4.8 5.9 1.9 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein ADH_N PF08240.7 EPS34585.1 - 6.7e-27 93.4 2.3 6.7e-27 93.4 1.6 2.2 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 EPS34585.1 - 2.8e-05 23.6 1.7 2.8e-05 23.6 1.2 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.21 EPS34585.1 - 0.00016 21.1 0.3 0.079 12.5 0.0 2.8 3 0 0 3 3 3 2 Zinc-binding dehydrogenase Peptidase_M18 PF02127.10 EPS34586.1 - 4.6e-131 437.2 0.0 5.2e-131 437.0 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) DUF3995 PF13160.1 EPS34587.1 - 0.6 10.1 6.5 0.15 12.0 1.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3995) NOB1_Zn_bind PF08772.6 EPS34588.1 - 9.1e-30 102.3 4.9 1.7e-29 101.4 3.4 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like Mitofilin PF09731.4 EPS34588.1 - 0.02 13.5 10.0 0.027 13.1 6.9 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Daxx PF03344.10 EPS34588.1 - 0.023 13.1 12.4 0.038 12.5 8.6 1.3 1 0 0 1 1 1 0 Daxx Family Senescence_reg PF04520.8 EPS34588.1 - 0.23 11.9 9.4 0.46 10.9 6.5 1.4 1 0 0 1 1 1 0 Senescence regulator Nop14 PF04147.7 EPS34588.1 - 0.39 8.5 17.1 0.56 8.0 11.8 1.1 1 0 0 1 1 1 0 Nop14-like family Hid1 PF12722.2 EPS34588.1 - 1 6.9 5.2 1.2 6.6 3.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ycf1 PF05758.7 EPS34588.1 - 1.4 6.4 5.9 1.7 6.2 4.1 1.1 1 0 0 1 1 1 0 Ycf1 SAPS PF04499.10 EPS34588.1 - 6.2 5.3 8.5 7.8 5.0 5.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nop10p PF04135.7 EPS34589.1 - 6.1e-20 70.7 0.2 7.5e-20 70.4 0.1 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family tRNA_int_endo PF01974.12 EPS34590.1 - 7.1e-22 77.0 0.2 1.7e-21 75.8 0.1 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 EPS34590.1 - 3.6e-08 32.8 0.0 0.00026 20.4 0.0 2.4 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Rad9_Rad53_bind PF08605.5 EPS34591.1 - 6.7e-25 87.3 0.0 1.1e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.21 EPS34591.1 - 4.4e-10 39.5 0.0 3.4e-09 36.7 0.0 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Ribosomal_L27 PF01016.14 EPS34592.1 - 9.8e-27 92.5 0.0 1.6e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein Scramblase PF03803.10 EPS34594.1 - 5.3e-52 176.0 0.1 1.8e-27 95.8 0.0 3.0 2 1 0 2 2 2 2 Scramblase UQ_con PF00179.21 EPS34595.1 - 7.5e-50 167.9 0.0 8.5e-50 167.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TP6A_N PF04406.9 EPS34596.1 - 4.8e-18 64.5 0.2 8.4e-18 63.8 0.1 1.4 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Prenyltrans_2 PF13249.1 EPS34597.1 - 7.7e-40 135.8 6.5 1.6e-13 51.0 0.2 5.1 3 1 3 6 6 6 6 Prenyltransferase-like Prenyltrans PF00432.16 EPS34597.1 - 1.7e-31 107.4 2.0 3.6e-09 36.0 0.1 4.5 4 0 0 4 4 4 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 EPS34597.1 - 7.8e-26 90.2 0.4 9.1e-11 41.7 0.1 6.1 4 1 1 6 6 6 4 Prenyltransferase-like Pec_lyase PF09492.5 EPS34597.1 - 8.3e-07 28.4 3.7 1.4 8.0 0.0 4.7 3 1 2 5 5 5 3 Pectic acid lyase SGS PF05002.10 EPS34598.1 - 4.1e-27 93.7 1.6 4.1e-27 93.7 1.1 2.0 2 0 0 2 2 2 1 SGS domain CS PF04969.11 EPS34598.1 - 1.1e-15 57.8 0.0 1.9e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 CS domain TPR_11 PF13414.1 EPS34598.1 - 1.1e-05 24.9 3.1 5.1e-05 22.8 0.7 2.5 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 EPS34598.1 - 0.012 15.2 0.2 2.1 8.0 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat CDC27 PF09507.5 EPS34598.1 - 1.7 7.8 12.6 0.087 12.0 1.1 2.2 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 GATase PF00117.23 EPS34599.1 - 0.0096 15.3 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I PQ-loop PF04193.9 EPS34600.1 - 9.3e-41 137.2 10.0 5.4e-21 73.9 1.1 2.6 2 0 0 2 2 2 2 PQ loop repeat DUF3784 PF12650.2 EPS34600.1 - 0.043 13.7 0.9 8 6.4 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) FixQ PF05545.6 EPS34600.1 - 2 8.1 6.1 11 5.7 0.0 3.8 4 0 0 4 4 4 0 Cbb3-type cytochrome oxidase component FixQ tRNA-synt_1e PF01406.14 EPS34601.1 - 3.8e-115 384.1 0.0 6.3e-115 383.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EPS34601.1 - 2.2e-06 26.6 0.6 0.024 13.2 0.1 2.8 3 0 0 3 3 3 2 tRNA synthetases class I (M) DALR_2 PF09190.6 EPS34601.1 - 0.0016 18.6 0.5 0.0084 16.3 0.0 2.4 2 0 0 2 2 2 1 DALR domain GCD14 PF08704.5 EPS34602.1 - 9.6e-60 202.1 0.4 3.7e-59 200.2 0.0 2.2 2 1 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 EPS34602.1 - 2.5e-05 24.2 0.0 0.00019 21.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS34602.1 - 0.014 15.9 0.0 0.028 15.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 EPS34602.1 - 0.11 11.5 0.0 0.89 8.5 0.0 2.3 2 1 0 2 2 2 0 Ribosomal RNA adenine dimethylase YscO PF07321.7 EPS34602.1 - 0.4 10.5 9.8 0.97 9.2 6.8 1.6 1 0 0 1 1 1 0 Type III secretion protein YscO TPR_11 PF13414.1 EPS34603.1 - 4e-07 29.5 0.1 7.4e-06 25.5 0.0 2.7 3 0 0 3 3 3 1 TPR repeat UBA PF00627.26 EPS34603.1 - 4e-07 29.6 0.0 1.1e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain TPR_16 PF13432.1 EPS34603.1 - 2.3e-05 24.9 1.8 0.014 16.0 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EPS34603.1 - 7.4e-05 22.3 2.2 0.049 13.5 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EPS34603.1 - 0.0073 15.8 0.7 1.6 8.4 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EPS34603.1 - 0.042 13.7 1.6 2.1 8.3 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EPS34603.1 - 0.12 13.0 2.1 18 6.2 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4203 PF13886.1 EPS34604.1 - 5.4e-36 124.0 23.4 7.1e-36 123.6 16.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) CHAT PF12770.2 EPS34606.1 - 1.7e-35 122.5 0.1 2.8e-35 121.8 0.1 1.4 1 0 0 1 1 1 1 CHAT domain Peptidase_C50 PF03568.12 EPS34606.1 - 0.0038 15.9 0.1 0.036 12.7 0.0 2.2 2 0 0 2 2 2 1 Peptidase family C50 TPR_14 PF13428.1 EPS34606.1 - 0.0053 17.2 6.1 17 6.3 0.0 5.9 5 0 0 5 5 5 1 Tetratricopeptide repeat Peptidase_C25 PF01364.13 EPS34606.1 - 0.12 11.3 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C25 Ribonucleas_3_3 PF14622.1 EPS34607.1 - 1.5e-09 37.9 0.0 2.4e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EPS34607.1 - 3.4e-08 33.9 0.0 7e-08 32.9 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease III domain Erf4 PF10256.4 EPS34608.1 - 1.2e-32 112.2 0.0 1.8e-32 111.7 0.0 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family HNF-1A_C PF04813.7 EPS34608.1 - 0.0026 18.0 0.1 0.0053 16.9 0.1 1.4 1 0 0 1 1 1 1 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus Adap_comp_sub PF00928.16 EPS34609.1 - 2.9e-86 288.8 0.0 3.6e-86 288.5 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EPS34609.1 - 0.00071 19.3 0.1 0.0012 18.5 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 EPS34609.1 - 0.00071 18.8 0.1 0.0012 18.1 0.1 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain PRCC PF10253.4 EPS34610.1 - 3.7 8.1 5.9 37 4.9 1.7 2.3 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Pkinase PF00069.20 EPS34611.1 - 1.4e-06 27.6 0.0 1.9e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase PF00069.20 EPS34612.1 - 0.00077 18.6 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS34612.1 - 0.049 12.7 0.1 0.061 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase DUF4276 PF14103.1 EPS34612.1 - 0.06 13.2 0.0 0.084 12.7 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4276) FHA PF00498.21 EPS34613.1 - 8.4e-06 25.8 0.0 1.4e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 FHA domain Ank_5 PF13857.1 EPS34614.1 - 5.7e-06 26.3 0.1 1.4e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 EPS34614.1 - 6.7e-05 22.4 0.4 0.0002 21.0 0.3 1.8 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.2 EPS34614.1 - 0.001 19.3 0.0 0.0061 16.8 0.0 2.3 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EPS34614.1 - 0.053 13.7 0.0 0.17 12.2 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeat ABC_membrane PF00664.18 EPS34615.1 - 1.7e-75 254.0 26.9 2.3e-39 135.4 6.3 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EPS34615.1 - 1.2e-52 177.7 0.0 1.1e-30 106.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EPS34615.1 - 1.7e-10 40.4 4.5 0.0023 17.1 0.2 4.1 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EPS34615.1 - 2.2e-06 27.8 2.3 0.027 14.4 0.3 2.9 3 0 0 3 3 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 EPS34615.1 - 1.9e-05 24.5 0.0 0.35 10.8 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.1 EPS34615.1 - 4.1e-05 23.6 3.3 0.97 9.3 0.0 4.9 4 1 1 5 5 5 1 AAA domain AAA_29 PF13555.1 EPS34615.1 - 6e-05 22.5 0.2 0.64 9.5 0.0 3.0 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EPS34615.1 - 0.00023 20.3 0.1 0.071 12.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EPS34615.1 - 0.00033 20.5 0.5 0.057 13.2 0.0 2.8 2 0 0 2 2 2 1 Dynamin family AAA_25 PF13481.1 EPS34615.1 - 0.00048 19.5 0.0 1 8.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EPS34615.1 - 0.00085 19.6 0.0 0.11 12.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 EPS34615.1 - 0.0011 18.8 0.8 0.9 9.3 0.0 2.8 2 0 0 2 2 2 2 Domain of unknown function DUF87 Miro PF08477.8 EPS34615.1 - 0.003 18.0 1.3 3.4 8.1 0.1 2.9 2 0 0 2 2 2 2 Miro-like protein AAA_30 PF13604.1 EPS34615.1 - 0.0068 16.0 1.5 1.7 8.1 0.0 3.3 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EPS34615.1 - 0.011 14.8 0.1 2.9 6.9 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin MobB PF03205.9 EPS34615.1 - 0.059 13.0 0.5 6 6.5 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EPS34615.1 - 0.13 13.1 0.4 9.3 7.0 0.2 3.0 2 1 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 EPS34615.1 - 0.13 11.6 0.0 13 5.2 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EPS34615.1 - 0.15 12.1 1.2 16 5.6 0.0 3.3 2 1 0 2 2 2 0 AAA domain AIG1 PF04548.11 EPS34615.1 - 0.21 10.6 1.4 4.3 6.3 0.0 2.6 2 0 0 2 2 2 0 AIG1 family AAA_10 PF12846.2 EPS34615.1 - 0.23 10.8 3.1 6.7 6.0 0.0 2.9 2 1 0 2 2 2 0 AAA-like domain NACHT PF05729.7 EPS34615.1 - 1.3 8.6 4.8 1.7 8.2 0.1 3.0 3 0 0 3 3 3 0 NACHT domain DUF2841 PF11001.3 EPS34617.1 - 4.7e-44 149.2 0.1 7.5e-44 148.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) SAC3_GANP PF03399.11 EPS34618.1 - 2.3e-52 177.5 1.5 3.5e-52 176.9 1.1 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EPS34618.1 - 0.0019 17.9 0.5 0.0056 16.4 0.2 1.9 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 ACPS PF01648.15 EPS34618.1 - 2.8 7.7 6.0 8.5 6.2 3.4 2.3 2 1 0 2 2 2 0 4'-phosphopantetheinyl transferase superfamily CN_hydrolase PF00795.17 EPS34619.1 - 5.4e-11 42.1 0.0 1.2e-10 41.0 0.0 1.6 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase HLH PF00010.21 EPS34621.1 - 7.5e-14 51.1 2.0 1.6e-13 50.1 1.4 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DPBB_1 PF03330.13 EPS34622.1 - 5e-10 39.2 0.2 1.9e-09 37.4 0.0 2.1 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Pollen_allerg_1 PF01357.16 EPS34622.1 - 0.00099 18.8 0.2 0.0024 17.6 0.2 1.7 1 0 0 1 1 1 1 Pollen allergen Mo-co_dimer PF03404.11 EPS34622.1 - 0.0026 17.3 0.0 0.0049 16.5 0.0 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain BNR PF02012.15 EPS34622.1 - 0.02 14.6 0.7 0.088 12.6 0.5 2.2 1 0 0 1 1 1 0 BNR/Asp-box repeat Barwin PF00967.12 EPS34622.1 - 0.021 14.5 0.3 0.054 13.1 0.0 1.8 2 0 0 2 2 2 0 Barwin family Macoilin PF09726.4 EPS34622.1 - 9.4 4.3 15.0 12 4.0 10.4 1.1 1 0 0 1 1 1 0 Transmembrane protein Sec8_exocyst PF04048.9 EPS34623.1 - 1.8e-49 167.0 1.1 4.5e-49 165.7 0.8 1.7 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 EPS34623.1 - 2e-08 33.4 0.3 3.9e-08 32.5 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Dor1 PF04124.7 EPS34623.1 - 0.00018 20.0 2.5 0.00038 19.0 1.8 1.5 1 0 0 1 1 1 1 Dor1-like family Zw10 PF06248.8 EPS34623.1 - 0.0016 16.7 1.0 0.0033 15.6 0.4 1.7 2 0 0 2 2 2 1 Centromere/kinetochore Zw10 Sec5 PF15469.1 EPS34623.1 - 0.0026 17.4 0.3 0.0055 16.4 0.2 1.5 1 0 0 1 1 1 1 Exocyst complex component Sec5 TPP_enzyme_N PF02776.13 EPS34623.1 - 0.054 12.9 0.2 0.33 10.4 0.0 2.3 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Peptidase_M24 PF00557.19 EPS34624.1 - 7.5e-40 136.7 0.0 1.1e-39 136.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EPS34624.1 - 7.3e-21 75.0 0.0 7.2e-19 68.5 0.0 2.8 3 0 0 3 3 3 1 Creatinase/Prolidase N-terminal domain E3_binding PF02817.12 EPS34624.1 - 0.012 15.2 0.0 9.4 5.9 0.0 3.8 4 0 0 4 4 4 0 e3 binding domain MUG113 PF13455.1 EPS34625.1 - 1.4e-35 121.5 0.2 2.7e-35 120.6 0.1 1.5 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 EPS34625.1 - 9e-25 86.9 0.0 2.1e-24 85.7 0.0 1.6 1 0 0 1 1 1 1 T5orf172 domain SnoaL PF07366.7 EPS34626.1 - 0.00088 18.8 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EPS34626.1 - 0.02 15.2 0.1 0.037 14.4 0.1 1.4 1 0 0 1 1 1 0 SnoaL-like domain SOR_SNZ PF01680.12 EPS34629.1 - 3.7e-110 366.4 6.0 6.6e-110 365.6 4.2 1.4 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 EPS34629.1 - 1.5e-08 34.0 11.0 1.2e-06 27.7 0.5 2.6 2 2 1 3 3 3 2 Thiazole biosynthesis protein ThiG Dus PF01207.12 EPS34629.1 - 0.00063 18.6 1.3 0.27 10.0 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) IGPS PF00218.16 EPS34629.1 - 0.0023 17.0 0.1 0.053 12.5 0.0 2.5 2 1 0 2 2 2 1 Indole-3-glycerol phosphate synthase His_biosynth PF00977.16 EPS34629.1 - 0.0035 16.6 0.8 0.14 11.3 0.0 2.8 2 2 1 3 3 3 1 Histidine biosynthesis protein NanE PF04131.9 EPS34629.1 - 0.0056 15.6 0.9 0.16 10.9 0.0 2.5 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase NMO PF03060.10 EPS34629.1 - 0.019 14.1 0.5 0.019 14.1 0.3 2.4 2 1 0 2 2 2 0 Nitronate monooxygenase PEP_mutase PF13714.1 EPS34629.1 - 0.95 8.6 7.7 0.52 9.4 1.0 2.8 2 2 1 3 3 3 0 Phosphoenolpyruvate phosphomutase SecY PF00344.15 EPS34630.1 - 1.1e-97 327.0 8.1 1.4e-97 326.7 5.6 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EPS34630.1 - 2.7e-18 65.1 0.3 7.8e-18 63.6 0.2 1.9 1 0 0 1 1 1 1 Plug domain of Sec61p Phage_GP20 PF06810.6 EPS34631.1 - 0.017 14.6 4.2 0.029 13.8 2.9 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF3450 PF11932.3 EPS34631.1 - 0.086 12.0 7.0 0.13 11.4 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Phage_GPO PF05929.6 EPS34631.1 - 0.11 11.6 4.8 0.17 11.1 3.4 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF2570 PF10828.3 EPS34631.1 - 0.14 11.7 1.3 0.28 10.8 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Tweety PF04906.8 EPS34631.1 - 0.18 10.1 1.4 0.26 9.6 1.0 1.1 1 0 0 1 1 1 0 Tweety DUF4407 PF14362.1 EPS34631.1 - 0.74 8.7 6.2 1.1 8.1 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cyclin_N PF00134.18 EPS34632.1 - 0.00014 21.4 0.0 0.00065 19.2 0.0 2.1 2 1 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 EPS34632.1 - 0.00099 18.8 0.0 0.28 11.0 0.0 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Autophagy_N PF03986.8 EPS34633.1 - 1.6e-49 167.4 0.1 2.9e-49 166.5 0.0 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 EPS34633.1 - 1.6e-21 76.2 0.3 4e-21 74.9 0.2 1.7 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 EPS34633.1 - 1.9e-13 49.2 0.2 3.2e-13 48.5 0.1 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal OMP_b-brl PF13505.1 EPS34634.1 - 0.0028 17.5 0.1 0.0042 17.0 0.1 1.2 1 0 0 1 1 1 1 Outer membrane protein beta-barrel domain ArgJ PF01960.13 EPS34637.1 - 1.1e-144 481.5 0.1 1.3e-144 481.4 0.1 1.0 1 0 0 1 1 1 1 ArgJ family ORC2 PF04084.9 EPS34638.1 - 1.8e-95 319.5 0.0 2.4e-95 319.0 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 FliH PF02108.11 EPS34638.1 - 0.00072 19.4 0.1 0.0014 18.5 0.1 1.4 1 0 0 1 1 1 1 Flagellar assembly protein FliH ORC6 PF05460.8 EPS34638.1 - 1.1 8.2 13.1 1.7 7.6 9.1 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) FUN14 PF04930.10 EPS34639.1 - 5.6e-11 42.5 1.7 1.8e-10 40.9 1.2 1.8 1 1 0 1 1 1 1 FUN14 family DUF543 PF04418.7 EPS34639.1 - 3.7 7.5 8.5 12 5.9 1.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF543) Glycos_transf_2 PF00535.21 EPS34640.1 - 2.5e-20 72.8 0.0 5.8e-10 39.0 0.0 2.7 2 1 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EPS34640.1 - 4.6e-08 33.1 0.1 0.0075 16.0 0.0 3.7 3 1 1 4 4 4 2 Glycosyltransferase like family 2 EST1_DNA_bind PF10373.4 EPS34641.1 - 3.3e-07 29.7 0.3 8.4e-07 28.4 0.2 1.8 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain NUDIX PF00293.23 EPS34643.1 - 3.6e-05 23.4 0.1 8.7e-05 22.1 0.1 1.8 1 1 0 1 1 1 1 NUDIX domain NUDIX PF00293.23 EPS34644.1 - 1.6e-17 63.4 0.0 2.4e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain HAD_2 PF13419.1 EPS34645.1 - 2e-18 67.2 0.0 4.9e-18 65.9 0.0 1.5 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EPS34645.1 - 1.9e-08 33.8 0.0 3.5e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EPS34645.1 - 0.0014 19.0 0.3 0.0049 17.3 0.2 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hexokinase_1 PF00349.16 EPS34645.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Hexokinase Init_tRNA_PT PF04179.7 EPS34646.1 - 1e-168 561.8 0.0 1.2e-168 561.7 0.0 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase YfhD PF14151.1 EPS34646.1 - 0.032 14.3 0.0 0.079 13.0 0.0 1.6 1 0 0 1 1 1 0 YfhD-like protein LAG1-DNAbind PF09271.6 EPS34646.1 - 0.15 12.5 0.0 0.25 11.8 0.0 1.3 1 0 0 1 1 1 0 LAG1, DNA binding Aldo_ket_red PF00248.16 EPS34647.1 - 1e-51 175.4 0.0 1.2e-51 175.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family NMT1_2 PF13379.1 EPS34647.1 - 0.022 14.1 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 NMT1-like family ALMT PF11744.3 EPS34647.1 - 0.065 11.8 0.1 0.087 11.4 0.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter CH PF00307.26 EPS34648.1 - 2.9e-36 123.8 0.1 9.3e-19 67.4 0.0 2.7 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 EPS34648.1 - 1.6e-28 98.4 0.0 3.9e-28 97.2 0.0 1.7 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 EPS34648.1 - 2.6e-10 39.8 1.8 1.9e-06 27.3 0.0 3.2 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_6 PF13405.1 EPS34648.1 - 0.00057 19.5 0.0 0.004 16.9 0.0 2.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.27 EPS34648.1 - 0.0025 16.9 0.1 0.02 14.1 0.0 2.5 2 0 0 2 2 2 1 EF hand Rabaptin PF03528.10 EPS34648.1 - 0.0041 17.0 0.0 0.097 12.5 0.0 2.7 1 1 1 2 2 2 1 Rabaptin EF-hand_8 PF13833.1 EPS34648.1 - 0.012 15.1 0.1 0.081 12.5 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_7 PF13499.1 EPS34648.1 - 0.014 15.4 0.8 0.82 9.8 0.0 3.4 2 0 0 2 2 2 0 EF-hand domain pair Spectrin PF00435.16 EPS34648.1 - 0.031 14.5 7.9 0.3 11.3 0.0 3.4 3 0 0 3 3 3 0 Spectrin repeat RRM_1 PF00076.17 EPS34649.1 - 4.9e-15 54.9 0.0 7.5e-15 54.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EPS34649.1 - 3.3e-08 33.8 9.8 3.3e-08 33.8 6.8 4.1 3 1 1 4 4 4 1 C-terminal duplication domain of Friend of PRMT1 RRM_6 PF14259.1 EPS34649.1 - 1.2e-07 31.5 0.0 1.9e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS34649.1 - 0.0094 15.7 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EPS34650.1 - 1.5e-34 116.6 12.2 2.1e-10 40.0 0.0 6.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Me-amine-dh_H PF06433.6 EPS34650.1 - 0.0095 14.6 0.0 1.5 7.4 0.0 2.2 2 0 0 2 2 2 2 Methylamine dehydrogenase heavy chain (MADH) Cytochrom_D1 PF02239.11 EPS34650.1 - 0.014 13.6 0.0 0.025 12.9 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain PUL PF08324.6 EPS34651.1 - 7.8e-51 172.4 0.2 1.1e-50 171.9 0.2 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.6 EPS34651.1 - 1.8e-43 147.2 0.0 3.1e-43 146.4 0.0 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 EPS34651.1 - 2.1e-42 141.5 9.0 5e-08 32.5 0.0 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 EPS34651.1 - 0.0017 18.0 0.0 0.28 10.9 0.0 3.4 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region ADH_N PF08240.7 EPS34652.1 - 4.9e-29 100.2 1.8 3.5e-28 97.5 0.6 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPS34652.1 - 4.9e-16 58.4 0.0 8.8e-16 57.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EPS34652.1 - 0.0008 20.2 0.0 0.0018 19.2 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EPS34652.1 - 0.074 12.1 0.1 0.12 11.5 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_N_assoc PF13823.1 EPS34652.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated YjeF_N PF03853.10 EPS34653.1 - 2.7e-38 131.2 0.0 3.3e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Ribosomal_S16 PF00886.14 EPS34654.1 - 4.4e-25 87.1 0.1 5.4e-25 86.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S16 RRM_1 PF00076.17 EPS34656.1 - 5.2e-15 54.8 0.0 1.4e-12 47.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS34656.1 - 1.1e-08 34.9 0.0 8.8e-06 25.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Bot1p PF12298.3 EPS34659.1 - 5.4e-50 169.6 3.9 5.8e-50 169.5 0.1 2.1 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein Omp28 PF11551.3 EPS34659.1 - 0.093 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Outer membrane protein Omp28 HNH_2 PF13391.1 EPS34663.1 - 3.5e-08 33.1 0.0 7.1e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease Sugar_tr PF00083.19 EPS34664.1 - 1.5e-80 270.9 19.9 1.8e-80 270.7 13.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS34664.1 - 4.7e-20 71.6 29.4 4.7e-20 71.6 20.4 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EPS34664.1 - 0.0002 19.7 1.1 0.00034 18.9 0.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EPS34664.1 - 0.00022 19.7 1.3 0.00022 19.7 0.9 2.9 2 1 1 3 3 3 2 MFS/sugar transport protein OATP PF03137.15 EPS34664.1 - 0.0053 14.8 2.6 0.0071 14.4 0.0 2.0 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family Response_reg PF00072.19 EPS34666.1 - 1.9e-19 69.6 0.0 1.6e-12 47.4 0.0 2.2 2 0 0 2 2 2 2 Response regulator receiver domain PQ-loop PF04193.9 EPS34667.1 - 6.8e-21 73.5 14.0 2.6e-20 71.7 0.6 3.3 3 1 1 4 4 4 2 PQ loop repeat ABC2_membrane_5 PF13346.1 EPS34667.1 - 0.00024 20.4 5.0 0.13 11.4 0.0 2.1 2 0 0 2 2 2 2 ABC-2 family transporter protein UL2 PF08196.6 EPS34667.1 - 0.12 12.1 0.7 0.37 10.5 0.5 1.9 1 1 0 1 1 1 0 UL2 protein SH3_1 PF00018.23 EPS34668.1 - 2.5e-09 36.3 0.0 4.9e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EPS34668.1 - 2.7e-07 29.9 0.0 8.6e-07 28.3 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 EPS34668.1 - 5.3e-07 29.1 0.0 9.7e-07 28.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Bax1-I PF01027.15 EPS34668.1 - 0.085 12.4 13.6 0.12 11.9 9.4 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Herpes_LMP1 PF05297.6 EPS34668.1 - 0.089 11.6 0.3 4.1 6.2 0.0 2.2 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) UBA_4 PF14555.1 EPS34670.1 - 4.2e-11 42.2 0.5 1.4e-10 40.5 0.2 2.0 2 0 0 2 2 2 1 UBA-like domain UIM PF02809.15 EPS34670.1 - 0.0039 16.6 1.6 0.0099 15.3 1.1 1.7 1 0 0 1 1 1 1 Ubiquitin interaction motif SET PF00856.23 EPS34671.1 - 3.1e-16 60.1 0.6 2.3e-14 54.0 0.4 2.4 1 1 0 1 1 1 1 SET domain Gtr1_RagA PF04670.7 EPS34672.1 - 8.1e-94 313.0 0.2 9.9e-94 312.8 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EPS34672.1 - 3.1e-08 33.0 0.0 4.8e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EPS34672.1 - 3.1e-08 33.1 0.0 4.8e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 EPS34672.1 - 1.1e-05 25.3 0.0 2.3e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EPS34672.1 - 1.8e-05 25.2 0.0 3.7e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EPS34672.1 - 0.00026 20.4 0.0 0.00066 19.1 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 EPS34672.1 - 0.0026 17.2 0.3 0.0088 15.5 0.1 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF815 PF05673.8 EPS34672.1 - 0.0091 14.9 0.1 0.018 13.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.22 EPS34672.1 - 0.014 15.6 0.0 0.03 14.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.11 EPS34672.1 - 0.097 11.8 0.1 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AIG1 PF04548.11 EPS34672.1 - 0.13 11.3 0.2 0.39 9.7 0.0 1.9 2 0 0 2 2 2 0 AIG1 family AAA_10 PF12846.2 EPS34672.1 - 0.14 11.5 0.4 0.32 10.3 0.3 1.6 1 1 0 1 1 1 0 AAA-like domain G-alpha PF00503.15 EPS34672.1 - 0.16 10.6 3.0 2.7 6.5 0.8 2.2 1 1 1 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.1 EPS34672.1 - 0.21 11.5 0.5 0.84 9.5 0.3 2.0 1 1 0 1 1 1 0 AAA ATPase domain DUF1688 PF07958.6 EPS34673.1 - 1.4e-180 600.3 0.0 1.6e-180 600.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) SSB PF00436.20 EPS34676.1 - 2.4e-17 62.6 0.0 3e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family STE3 PF02076.10 EPS34677.1 - 6.5e-96 320.7 13.3 8.2e-96 320.4 9.2 1.1 1 0 0 1 1 1 1 Pheromone A receptor HsbA PF12296.3 EPS34678.1 - 0.02 14.7 0.7 0.044 13.6 0.1 1.9 2 0 0 2 2 2 0 Hydrophobic surface binding protein A Mnd1 PF03962.10 EPS34678.1 - 0.089 12.4 1.3 0.27 10.8 0.8 1.8 2 0 0 2 2 2 0 Mnd1 family IncA PF04156.9 EPS34678.1 - 0.11 12.0 0.9 0.84 9.1 1.1 2.2 2 0 0 2 2 2 0 IncA protein DUF3431 PF11913.3 EPS34679.1 - 2.1e-88 295.5 2.5 3.1e-88 295.0 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Ku PF02735.11 EPS34680.1 - 1.2e-37 129.3 0.0 2.4e-37 128.2 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EPS34680.1 - 7.9e-29 100.6 0.0 1.2e-28 100.0 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 EPS34680.1 - 2.3e-13 50.4 0.0 5.9e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.22 EPS34680.1 - 1.6e-05 24.2 0.0 3.2e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 SAP domain Ferrochelatase PF00762.14 EPS34681.1 - 7.7e-92 307.6 0.0 8.9e-92 307.4 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase MFS_1 PF07690.11 EPS34682.1 - 7.1e-29 100.6 28.1 6.1e-25 87.6 10.1 2.7 1 1 2 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS34682.1 - 3e-06 26.0 0.7 3e-06 26.0 0.5 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter DUF1751 PF08551.5 EPS34682.1 - 0.011 16.0 2.4 0.032 14.5 0.6 2.5 2 0 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) PPR PF01535.15 EPS34683.1 - 8.2e-08 31.7 1.5 0.097 12.6 0.0 4.9 5 0 0 5 5 5 3 PPR repeat PPR_3 PF13812.1 EPS34683.1 - 1.3e-07 31.3 0.3 0.00058 19.9 0.0 5.4 6 0 0 6 6 6 1 Pentatricopeptide repeat domain PPR_2 PF13041.1 EPS34683.1 - 1.2e-05 25.1 0.1 0.043 13.8 0.0 4.0 3 1 1 4 4 4 1 PPR repeat family TPR_19 PF14559.1 EPS34683.1 - 0.0075 16.5 0.0 5.5 7.4 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EPS34683.1 - 0.16 11.9 1.3 0.79 9.7 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat adh_short PF00106.20 EPS34684.1 - 3.7e-21 75.7 0.0 4.8e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPS34684.1 - 1.3e-08 34.9 0.0 1.9e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPS34684.1 - 1.5e-08 34.5 0.0 2.2e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPS34684.1 - 1.4e-05 24.6 0.0 3.4e-05 23.4 0.0 1.6 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EPS34684.1 - 3.7e-05 23.8 0.1 0.00033 20.7 0.0 2.2 2 1 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 EPS34684.1 - 0.014 14.7 0.1 0.026 13.8 0.1 1.5 1 0 0 1 1 1 0 NmrA-like family His_biosynth PF00977.16 EPS34684.1 - 0.033 13.4 0.0 0.047 12.9 0.0 1.2 1 0 0 1 1 1 0 Histidine biosynthesis protein Raftlin PF15250.1 EPS34684.1 - 0.095 11.2 0.0 0.1 11.0 0.0 1.1 1 0 0 1 1 1 0 Raftlin DUF239 PF03080.10 EPS34684.1 - 0.15 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF239) SE PF08491.5 EPS34685.1 - 1.5e-96 322.4 0.0 2.1e-96 321.9 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 EPS34685.1 - 1.3e-08 34.2 1.5 8.4e-06 25.0 0.3 2.4 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EPS34685.1 - 1.8e-08 33.6 0.3 2.4e-06 26.6 0.3 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPS34685.1 - 0.00094 19.1 0.5 0.0019 18.1 0.4 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EPS34685.1 - 0.0013 17.8 0.3 0.0018 17.4 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EPS34685.1 - 0.0014 17.7 0.0 0.0025 16.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EPS34685.1 - 0.0019 17.1 0.2 0.014 14.3 0.1 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EPS34685.1 - 0.003 16.4 0.7 0.003 16.4 0.5 1.4 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EPS34685.1 - 0.0043 17.4 0.1 0.009 16.3 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EPS34685.1 - 0.0065 15.1 0.5 0.46 9.0 0.1 2.4 2 1 0 2 2 2 1 Tryptophan halogenase GIDA PF01134.17 EPS34685.1 - 0.0068 15.3 0.0 0.044 12.6 0.0 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EPS34685.1 - 0.0069 16.2 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EPS34685.1 - 0.025 14.0 0.2 0.042 13.2 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EPS34685.1 - 0.046 13.3 0.1 0.071 12.7 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EPS34685.1 - 0.082 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ThiF PF00899.16 EPS34685.1 - 0.1 12.4 1.1 0.18 11.6 0.7 1.4 1 0 0 1 1 1 0 ThiF family HI0933_like PF03486.9 EPS34685.1 - 0.13 10.7 0.2 0.25 9.7 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein Caveolin PF01146.12 EPS34685.1 - 0.8 9.2 3.6 1.3 8.5 2.5 1.3 1 0 0 1 1 1 0 Caveolin Tox-GHH2 PF15635.1 EPS34686.1 - 0.2 12.0 2.7 0.22 11.8 1.6 1.4 1 1 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin 2 PAP_assoc PF03828.14 EPS34687.1 - 2.9e-18 65.5 0.0 5.9e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EPS34687.1 - 0.00025 21.3 0.0 0.00055 20.2 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF4298 PF14131.1 EPS34688.1 - 0.36 10.7 2.0 0.28 11.0 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) DUF914 PF06027.7 EPS34689.1 - 3.4e-106 354.9 18.9 4.1e-106 354.6 13.1 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EPS34689.1 - 0.00014 21.8 26.9 0.0016 18.4 8.2 2.5 2 1 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 EPS34689.1 - 1.9 8.0 24.2 0.12 11.9 6.0 2.5 2 1 0 2 2 2 0 Triose-phosphate Transporter family SMK-1 PF04802.10 EPS34690.1 - 1.4e-76 256.3 0.9 2.7e-76 255.4 0.6 1.5 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 DUF2305 PF10230.4 EPS34691.1 - 3.5e-81 272.5 0.0 4.1e-81 272.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 EPS34691.1 - 7.7e-06 25.9 0.2 2.3e-05 24.4 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPS34691.1 - 4.9e-05 23.1 0.0 0.00047 19.9 0.0 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPS34691.1 - 0.0036 16.9 0.0 0.021 14.3 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.8 EPS34691.1 - 0.041 13.4 0.0 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_3 PF07859.8 EPS34691.1 - 0.047 13.2 0.0 0.16 11.5 0.0 1.7 1 1 0 1 1 1 0 alpha/beta hydrolase fold DUF3089 PF11288.3 EPS34691.1 - 0.066 12.3 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Thioesterase PF00975.15 EPS34691.1 - 0.074 13.2 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 Thioesterase domain DUF726 PF05277.7 EPS34691.1 - 0.097 11.5 0.1 0.15 10.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) DCP1 PF06058.8 EPS34692.1 - 3.4e-17 62.6 0.0 1.1e-15 57.7 0.0 2.1 2 0 0 2 2 2 1 Dcp1-like decapping family Pex14_N PF04695.8 EPS34692.1 - 8.1 6.5 16.4 11 6.0 4.5 2.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Exo_endo_phos PF03372.18 EPS34693.1 - 3.4e-20 73.0 0.1 5.2e-20 72.4 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-CCCH PF00642.19 EPS34694.1 - 2.3e-08 33.5 0.6 4e-08 32.7 0.4 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 EPS34694.1 - 4.4e-08 32.6 4.7 7.3e-08 31.9 3.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EPS34694.1 - 6.2e-08 32.5 10.9 1e-07 31.8 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPS34694.1 - 2.5e-07 30.2 8.8 4e-07 29.6 6.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EPS34694.1 - 4.6e-07 29.5 7.2 7.4e-07 28.8 5.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EPS34694.1 - 1.8e-06 27.4 10.8 3e-06 26.7 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EPS34694.1 - 0.0014 18.4 9.2 0.0027 17.5 6.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EPS34694.1 - 0.028 14.1 6.0 0.064 12.9 4.1 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Cript PF10235.4 EPS34694.1 - 0.046 14.0 1.4 0.12 12.7 1.0 1.8 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT zf-Nse PF11789.3 EPS34694.1 - 0.048 13.1 2.6 0.087 12.3 1.8 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 EPS34694.1 - 2.3 8.3 7.3 6.6 6.9 5.1 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger Uso1_p115_C PF04871.8 EPS34694.1 - 3.1 7.7 10.8 0.22 11.4 2.1 2.1 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4611 PF15387.1 EPS34694.1 - 6.4 6.9 9.5 19 5.4 1.6 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Mcp5_PH PF12814.2 EPS34696.1 - 1.6e-43 147.5 0.2 3e-43 146.6 0.1 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology COMP PF11598.3 EPS34696.1 - 0.38 10.8 3.3 1.9 8.6 0.3 2.9 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein DUF3584 PF12128.3 EPS34696.1 - 3.4 4.8 45.5 0.33 8.2 22.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Methyltransf_23 PF13489.1 EPS34697.1 - 1.4e-14 54.1 0.0 2e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS34697.1 - 3.4e-08 34.0 0.0 6.5e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPS34697.1 - 1.3e-07 32.0 0.0 5.8e-07 29.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EPS34697.1 - 2.9e-06 27.6 0.0 1.6e-05 25.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EPS34697.1 - 1.5e-05 24.6 0.0 0.00045 19.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain DUF2439 PF10382.4 EPS34698.1 - 2.2e-28 98.2 0.4 3.5e-28 97.6 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) SH3_9 PF14604.1 EPS34699.1 - 2.5e-16 58.9 0.1 5.9e-16 57.7 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EPS34699.1 - 2.7e-13 49.1 0.1 4.4e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EPS34699.1 - 2.9e-12 45.7 0.1 4.9e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain BAR PF03114.13 EPS34699.1 - 9e-10 38.4 1.2 1.4e-09 37.8 0.8 1.2 1 0 0 1 1 1 1 BAR domain V-SNARE PF05008.10 EPS34699.1 - 0.079 13.1 4.4 4.3 7.5 0.5 3.0 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF4407 PF14362.1 EPS34699.1 - 0.095 11.6 0.7 0.15 10.9 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RTC PF01137.16 EPS34701.1 - 5.5e-36 123.4 0.0 3.8e-35 120.7 0.0 2.2 1 1 0 1 1 1 1 RNA 3'-terminal phosphate cyclase priB_priC PF07445.7 EPS34704.1 - 0.11 12.0 4.6 0.21 11.0 0.7 2.1 1 1 1 2 2 2 0 Primosomal replication protein priB and priC Exo_endo_phos PF03372.18 EPS34705.1 - 4.4e-17 62.8 1.0 6.4e-17 62.3 0.7 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CPSase_L_D2 PF02786.12 EPS34706.1 - 1.4e-56 191.1 0.0 2.5e-56 190.2 0.0 1.4 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 EPS34706.1 - 4.8e-32 110.1 0.0 9.5e-32 109.1 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 EPS34706.1 - 7.8e-28 96.7 0.0 1.5e-27 95.8 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EPS34706.1 - 1.2e-19 70.7 0.1 2.2e-19 69.9 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EPS34706.1 - 1.9e-13 49.8 0.0 1.6e-08 33.7 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EPS34706.1 - 9.2e-13 48.0 0.0 2.1e-12 46.8 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl PF00364.17 EPS34706.1 - 1.2e-10 40.8 0.4 4.1e-10 39.1 0.3 2.0 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.17 EPS34706.1 - 2.8e-09 36.5 0.1 5e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EPS34706.1 - 1.9e-05 24.2 0.4 0.00063 19.2 0.0 2.6 3 0 0 3 3 3 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EPS34706.1 - 4.3e-05 23.4 0.0 8.4e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EPS34706.1 - 0.00034 20.2 0.5 0.0021 17.6 0.1 2.2 2 0 0 2 2 2 1 Biotin-lipoyl like RnfC_N PF13375.1 EPS34706.1 - 0.0013 18.3 0.0 0.005 16.5 0.0 2.0 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain ATP-grasp_2 PF08442.5 EPS34706.1 - 0.022 14.1 0.3 0.12 11.7 0.0 2.1 2 0 0 2 2 2 0 ATP-grasp domain ATPgrasp_ST PF14397.1 EPS34706.1 - 0.027 13.5 0.0 0.052 12.6 0.0 1.4 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp GSH-S_ATP PF02955.11 EPS34706.1 - 0.029 13.5 0.0 0.075 12.1 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain Carboxyl_trans PF01039.17 EPS34707.1 - 3.6e-82 276.2 0.0 5e-82 275.8 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain S-methyl_trans PF02574.11 EPS34708.1 - 3.5e-29 102.0 0.0 1.1e-28 100.4 0.0 1.7 1 1 0 1 1 1 1 Homocysteine S-methyltransferase AA_permease PF00324.16 EPS34709.1 - 9.4e-114 380.3 42.8 1.1e-113 380.1 29.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPS34709.1 - 9.8e-41 139.6 47.0 1.3e-40 139.2 32.6 1.2 1 0 0 1 1 1 1 Amino acid permease DUF2422 PF10337.4 EPS34710.1 - 3.3e-109 365.7 0.1 1.4e-107 360.4 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2422) DUF2421 PF10334.4 EPS34710.1 - 6.9e-61 205.7 0.0 9.4e-60 202.0 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 EPS34710.1 - 1.1e-07 31.7 13.5 1.1e-07 31.7 9.3 3.3 3 1 0 3 3 3 1 Fusaric acid resistance protein-like HPP PF04982.8 EPS34711.1 - 1.6e-40 137.6 2.5 1.6e-40 137.6 1.7 1.7 2 0 0 2 2 2 1 HPP family DUF4149 PF13664.1 EPS34711.1 - 3.1 7.9 6.3 6.1 6.9 1.8 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) Pkinase PF00069.20 EPS34713.1 - 2.6e-20 72.6 0.0 5.3e-20 71.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS34713.1 - 1.3e-05 24.4 3.8 0.00076 18.6 0.0 3.1 3 1 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 EPS34713.1 - 0.00057 18.9 0.5 0.18 10.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like RNA_capsid PF03035.9 EPS34714.1 - 0.031 14.0 0.1 0.05 13.3 0.1 1.5 1 1 0 1 1 1 0 Calicivirus putative RNA polymerase/capsid protein CAP59_mtransfer PF11735.3 EPS34715.1 - 3e-82 275.4 0.0 1.4e-80 270.0 0.0 2.0 1 1 0 1 1 1 1 Cryptococcal mannosyltransferase 1 DUF1772 PF08592.6 EPS34716.1 - 0.019 14.6 0.1 0.37 10.5 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) adh_short_C2 PF13561.1 EPS34717.1 - 7.4e-22 78.2 0.0 1.1e-21 77.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EPS34717.1 - 4.8e-19 68.8 0.6 9.3e-19 67.9 0.4 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPS34717.1 - 6.7e-07 29.1 0.8 1.6e-06 27.9 0.1 1.7 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 EPS34717.1 - 0.025 13.5 0.1 0.033 13.0 0.1 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF4056 PF13265.1 EPS34717.1 - 0.031 13.2 0.1 0.05 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4056) Rop PF01815.11 EPS34718.1 - 0.13 11.7 4.5 4.1 6.9 1.3 2.7 2 0 0 2 2 2 0 Rop protein RabGAP-TBC PF00566.13 EPS34720.1 - 3.9e-47 160.4 0.0 7.1e-47 159.6 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.15 EPS34720.1 - 0.0025 17.3 0.0 0.0075 15.7 0.0 1.8 1 1 0 1 1 1 1 GRAM domain Sigma70_ner PF04546.8 EPS34720.1 - 4.5 6.8 14.5 1.2 8.6 0.3 2.7 3 0 0 3 3 3 0 Sigma-70, non-essential region CNH PF00780.17 EPS34721.1 - 4.1e-70 236.3 0.0 6.3e-70 235.7 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 EPS34721.1 - 1.6e-31 109.6 0.6 2.7e-31 108.8 0.4 1.4 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 EPS34721.1 - 1.2e-11 44.7 0.0 4.2e-11 42.9 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain 2OG-FeII_Oxy_2 PF13532.1 EPS34722.1 - 4.9e-25 88.4 0.0 7.9e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AMP-binding PF00501.23 EPS34723.1 - 1.2e-77 261.1 0.0 1.5e-77 260.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPS34723.1 - 1.6e-15 57.8 0.3 4.3e-15 56.4 0.2 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Abhydrolase_3 PF07859.8 EPS34724.1 - 2.3e-14 53.4 0.0 3.5e-14 52.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EPS34724.1 - 4.2e-09 36.6 0.1 5.6e-09 36.2 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EPS34724.1 - 8e-09 35.0 0.0 0.00059 19.1 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 EPS34724.1 - 1.4e-08 33.9 0.0 2.1e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_5 PF12695.2 EPS34724.1 - 2.2e-07 30.7 0.0 4.3e-07 29.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 EPS34724.1 - 7.3e-06 24.9 0.0 1e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase COesterase PF00135.23 EPS34724.1 - 0.00011 21.1 0.0 0.0078 14.9 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family AXE1 PF05448.7 EPS34724.1 - 0.00023 19.7 0.0 0.24 9.8 0.0 2.4 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Esterase PF00756.15 EPS34724.1 - 0.0007 19.0 0.1 0.0025 17.2 0.1 1.9 1 1 1 2 2 2 1 Putative esterase WD40 PF00400.27 EPS34725.1 - 2.2e-32 109.7 0.2 1.1e-07 31.4 0.0 8.1 8 0 0 8 8 8 5 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EPS34725.1 - 0.002 17.5 0.0 1.5 8.3 0.0 3.3 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain NDUF_B12 PF08122.7 EPS34727.1 - 3.1e-19 68.4 0.6 4.9e-19 67.8 0.4 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family ESSS PF10183.4 EPS34727.1 - 0.036 14.4 0.1 0.047 14.0 0.1 1.1 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) CAF1 PF04857.15 EPS34728.1 - 7.1e-65 218.9 0.0 1e-64 218.4 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease Cu_amine_oxid PF01179.15 EPS34729.1 - 1.6e-171 570.5 0.0 2e-171 570.2 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EPS34729.1 - 6.4e-22 77.5 0.3 3.9e-21 75.0 0.1 2.2 1 1 1 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EPS34729.1 - 1.8e-13 50.3 0.0 3.3e-13 49.4 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain TPR_11 PF13414.1 EPS34730.1 - 1.3e-10 40.7 2.6 1.7e-07 30.7 0.2 3.4 3 1 1 4 4 4 2 TPR repeat TPR_2 PF07719.12 EPS34730.1 - 2.2e-08 33.3 3.0 0.0022 17.7 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EPS34730.1 - 8.7e-05 23.0 1.3 0.2 12.3 0.7 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EPS34730.1 - 0.00021 20.7 2.0 0.34 10.5 0.3 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EPS34730.1 - 0.00024 20.9 1.8 0.29 11.1 0.0 3.1 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EPS34730.1 - 0.0058 16.3 0.3 0.035 13.8 0.0 2.4 3 0 0 3 3 3 1 Tetratricopeptide repeat MIT PF04212.13 EPS34730.1 - 0.02 14.7 0.6 1.2 9.1 0.2 2.3 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_19 PF14559.1 EPS34730.1 - 0.022 15.0 0.0 1.6 9.1 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 EPS34730.1 - 0.045 13.5 0.3 2.4 8.1 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Nucleopor_Nup85 PF07575.8 EPS34730.1 - 0.13 10.4 0.0 3.9 5.5 0.0 2.0 2 0 0 2 2 2 0 Nup85 Nucleoporin TPR_14 PF13428.1 EPS34730.1 - 0.17 12.6 1.9 1.8 9.3 0.0 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EPS34730.1 - 0.17 12.3 1.3 13 6.5 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat MARVEL PF01284.18 EPS34731.1 - 0.00015 21.6 9.7 0.00022 21.0 6.7 1.3 1 0 0 1 1 1 1 Membrane-associating domain Ank_2 PF12796.2 EPS34736.1 - 1.8e-53 178.8 0.0 1.5e-15 57.2 0.0 2.8 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EPS34736.1 - 4.2e-28 95.7 0.8 3.7e-06 26.4 0.0 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 EPS34736.1 - 1.1e-25 89.5 1.1 1e-06 29.1 0.1 4.1 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPS34736.1 - 4.5e-19 66.6 0.0 0.0085 16.2 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 EPS34736.1 - 2.3e-18 65.8 0.5 3.3e-07 30.3 0.0 4.3 1 1 3 4 4 4 4 Ankyrin repeats (many copies) F-box-like PF12937.2 EPS34736.1 - 0.00076 19.1 0.5 0.0016 18.1 0.4 1.5 1 0 0 1 1 1 1 F-box-like DUF2384 PF09722.5 EPS34736.1 - 0.14 12.0 1.2 14 5.6 0.1 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2384) Methyltransf_3 PF01596.12 EPS34737.1 - 8.6e-18 64.1 0.0 1.2e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EPS34737.1 - 2.8e-13 50.5 0.0 4.4e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EPS34737.1 - 0.0045 16.9 0.3 0.012 15.6 0.2 1.8 1 1 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 EPS34737.1 - 0.0051 16.1 0.0 0.0091 15.3 0.0 1.4 1 0 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_18 PF12847.2 EPS34737.1 - 0.01 16.4 0.0 0.015 15.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF2119 PF09892.4 EPS34737.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2119) GFO_IDH_MocA PF01408.17 EPS34738.1 - 2.5e-28 98.9 0.2 4.5e-28 98.1 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EPS34738.1 - 6e-12 45.3 0.0 9.6e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 EPS34738.1 - 1.4e-06 28.6 0.1 3e-06 27.6 0.1 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.15 EPS34738.1 - 0.0001 22.1 0.1 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 EPS34738.1 - 0.0028 17.9 0.1 0.0064 16.7 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain CoA_binding PF02629.14 EPS34738.1 - 0.011 16.2 0.5 0.028 14.9 0.4 1.7 1 1 0 1 1 1 0 CoA binding domain CoA_binding_2 PF13380.1 EPS34738.1 - 0.011 15.8 0.2 0.029 14.5 0.1 1.7 1 0 0 1 1 1 0 CoA binding domain OCD_Mu_crystall PF02423.10 EPS34738.1 - 0.041 12.6 0.1 0.061 12.0 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family CPSase_L_chain PF00289.17 EPS34738.1 - 0.098 12.7 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain HPP PF04982.8 EPS34739.1 - 8.1e-34 116.0 8.8 1.4e-33 115.2 6.1 1.4 1 0 0 1 1 1 1 HPP family DUF1614 PF07758.6 EPS34739.1 - 0.059 13.0 0.3 0.12 12.1 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1614) ABC_tran PF00005.22 EPS34740.1 - 1.1e-45 155.2 0.0 3e-22 79.4 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 EPS34740.1 - 3.2e-20 71.7 1.0 3.2e-20 71.7 0.7 2.8 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EPS34740.1 - 6.8e-20 72.2 0.3 0.00013 22.0 0.0 4.2 3 1 0 4 4 4 4 AAA domain SMC_N PF02463.14 EPS34740.1 - 2.9e-10 39.7 0.2 0.015 14.5 0.0 4.5 3 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EPS34740.1 - 5e-09 35.5 0.2 0.00065 19.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EPS34740.1 - 4.8e-08 33.5 1.5 0.071 13.4 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EPS34740.1 - 2.5e-07 30.9 0.0 0.034 14.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EPS34740.1 - 1.1e-06 27.9 0.0 0.0013 17.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EPS34740.1 - 2.1e-06 28.5 0.0 0.022 15.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EPS34740.1 - 5.1e-06 26.9 0.0 0.018 15.5 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_28 PF13521.1 EPS34740.1 - 7.8e-06 25.9 0.0 0.0065 16.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EPS34740.1 - 1.2e-05 25.6 0.1 0.029 14.6 0.0 3.0 3 0 0 3 3 2 1 AAA domain NACHT PF05729.7 EPS34740.1 - 1.6e-05 24.5 0.1 0.062 12.9 0.0 2.5 2 0 0 2 2 2 2 NACHT domain MMR_HSR1 PF01926.18 EPS34740.1 - 3.2e-05 23.8 0.1 0.063 13.2 0.0 3.0 3 1 1 4 4 2 1 50S ribosome-binding GTPase AAA PF00004.24 EPS34740.1 - 3.7e-05 23.9 0.0 0.46 10.6 0.0 3.0 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EPS34740.1 - 5.6e-05 23.2 0.2 0.24 11.3 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain RNA_helicase PF00910.17 EPS34740.1 - 5.8e-05 23.2 0.2 0.58 10.3 0.0 3.3 3 0 0 3 3 3 2 RNA helicase AAA_10 PF12846.2 EPS34740.1 - 0.00012 21.6 0.3 1 8.7 0.1 3.4 4 0 0 4 4 4 2 AAA-like domain AAA_33 PF13671.1 EPS34740.1 - 0.0002 21.2 1.1 0.25 11.2 0.0 3.0 4 0 0 4 4 2 2 AAA domain AAA_25 PF13481.1 EPS34740.1 - 0.00027 20.4 0.0 0.82 9.0 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.9 EPS34740.1 - 0.00094 18.9 0.2 1.2 8.8 0.1 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_15 PF13175.1 EPS34740.1 - 0.0012 18.0 0.0 0.23 10.4 0.0 3.0 4 0 0 4 4 3 1 AAA ATPase domain Arch_ATPase PF01637.13 EPS34740.1 - 0.0012 18.6 0.0 0.95 9.1 0.0 3.0 3 0 0 3 3 3 1 Archaeal ATPase AAA_14 PF13173.1 EPS34740.1 - 0.0017 18.2 0.0 2.6 7.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EPS34740.1 - 0.0044 16.9 1.2 0.29 11.0 0.0 3.5 3 2 0 3 3 2 1 Putative exonuclease SbcCD, C subunit MobB PF03205.9 EPS34740.1 - 0.0054 16.4 1.3 0.32 10.7 0.1 2.9 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 EPS34740.1 - 0.0062 15.4 0.0 3.8 6.2 0.0 3.0 3 0 0 3 3 3 1 NB-ARC domain DUF2813 PF11398.3 EPS34740.1 - 0.02 13.9 0.4 4.1 6.3 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2813) DAP3 PF10236.4 EPS34740.1 - 0.021 13.7 0.8 3.1 6.6 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 Ras PF00071.17 EPS34740.1 - 0.047 13.0 0.0 4.9 6.5 0.0 2.7 2 0 0 2 2 2 0 Ras family VirE PF05272.6 EPS34740.1 - 0.054 12.9 0.3 4.5 6.6 0.0 2.8 3 0 0 3 3 3 0 Virulence-associated protein E NTPase_1 PF03266.10 EPS34740.1 - 0.064 12.9 0.1 6.8 6.3 0.0 2.6 2 0 0 2 2 2 0 NTPase ATP-synt_ab PF00006.20 EPS34740.1 - 0.082 12.3 0.0 0.62 9.5 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.4 EPS34740.1 - 0.13 11.7 0.8 8.4 5.8 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 EPS34740.1 - 0.22 11.0 3.1 9.1 5.7 0.0 3.4 4 0 0 4 4 4 0 AAA domain AAA_13 PF13166.1 EPS34740.1 - 0.24 9.7 2.0 8 4.7 0.0 3.3 3 1 0 3 3 3 0 AAA domain Dynamin_N PF00350.18 EPS34740.1 - 0.29 10.9 4.5 10 5.8 0.0 3.7 4 1 1 5 5 4 0 Dynamin family DUF87 PF01935.12 EPS34740.1 - 2.1 8.0 7.4 11 5.7 0.0 3.5 4 1 1 5 5 3 0 Domain of unknown function DUF87 Cyclin_N PF00134.18 EPS34741.1 - 9.8e-07 28.3 0.0 2.4e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain UQ_con PF00179.21 EPS34742.1 - 6.7e-43 145.4 0.0 8.3e-43 145.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 EPS34742.1 - 1.6e-05 24.3 0.0 2.9e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 EPS34742.1 - 0.00015 21.4 0.0 0.00022 20.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EPS34742.1 - 0.013 15.2 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.17 EPS34742.1 - 0.019 14.8 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 RWD domain AAA PF00004.24 EPS34743.1 - 9.5e-41 139.0 0.0 1.9e-40 138.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EPS34743.1 - 7e-07 29.4 0.1 0.00022 21.3 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EPS34743.1 - 2.3e-06 27.3 0.0 6.3e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EPS34743.1 - 1.2e-05 25.3 0.0 2.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EPS34743.1 - 1.4e-05 24.2 0.0 2.4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 EPS34743.1 - 0.00017 21.6 0.1 0.0073 16.3 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 EPS34743.1 - 0.0006 18.9 0.0 0.001 18.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EPS34743.1 - 0.0017 18.3 0.2 0.0046 16.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_14 PF13173.1 EPS34743.1 - 0.0033 17.3 0.0 0.006 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EPS34743.1 - 0.0047 17.7 0.3 0.014 16.2 0.2 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EPS34743.1 - 0.0069 15.8 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EPS34743.1 - 0.0071 16.0 0.3 0.016 14.9 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 EPS34743.1 - 0.0077 15.3 0.0 0.018 14.1 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 EPS34743.1 - 0.011 15.5 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 EPS34743.1 - 0.015 14.9 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EPS34743.1 - 0.017 14.7 0.1 0.34 10.5 0.1 2.3 1 1 1 2 2 2 0 NACHT domain AAA_18 PF13238.1 EPS34743.1 - 0.018 15.3 0.1 0.043 14.1 0.1 1.8 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.8 EPS34743.1 - 0.019 13.6 0.0 0.043 12.5 0.0 1.5 1 0 0 1 1 1 0 TIP49 C-terminus PhoH PF02562.11 EPS34743.1 - 0.024 13.8 0.7 0.21 10.7 0.1 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.1 EPS34743.1 - 0.029 13.7 1.5 0.24 10.8 0.3 2.3 1 1 1 2 2 2 0 AAA domain NB-ARC PF00931.17 EPS34743.1 - 0.036 12.9 0.0 0.051 12.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.1 EPS34743.1 - 0.043 13.4 0.2 0.14 11.7 0.2 1.8 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EPS34743.1 - 0.044 13.9 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase KaiC PF06745.8 EPS34743.1 - 0.046 12.8 0.2 0.47 9.5 0.0 2.1 1 1 1 2 2 2 0 KaiC Mg_chelatase PF01078.16 EPS34743.1 - 0.054 12.6 0.1 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 EPS34743.1 - 0.099 12.3 0.1 0.55 9.9 0.0 2.3 3 0 0 3 3 3 0 NTPase DUF2075 PF09848.4 EPS34743.1 - 0.16 10.9 0.1 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) WD40 PF00400.27 EPS34744.1 - 1.3e-19 69.2 19.2 5.6e-07 29.1 1.3 6.3 7 0 0 7 7 7 4 WD domain, G-beta repeat Senescence_reg PF04520.8 EPS34744.1 - 0.0042 17.5 3.3 0.013 16.0 2.3 1.7 1 0 0 1 1 1 1 Senescence regulator Sigma70_ner PF04546.8 EPS34744.1 - 0.074 12.6 3.0 0.14 11.8 2.1 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region PBP1_TM PF14812.1 EPS34744.1 - 0.34 11.2 14.3 0.036 14.3 6.3 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 EPS34744.1 - 0.74 9.3 6.0 1.4 8.3 4.2 1.4 1 0 0 1 1 1 0 Nucleoplasmin FAM176 PF14851.1 EPS34744.1 - 1.1 8.8 5.6 2.5 7.7 3.9 1.5 1 0 0 1 1 1 0 FAM176 family Cwf_Cwc_15 PF04889.7 EPS34744.1 - 1.3 8.7 10.2 3.2 7.3 7.1 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein CENP-B_dimeris PF09026.5 EPS34744.1 - 1.9 8.8 10.3 4 7.7 7.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NOA36 PF06524.7 EPS34744.1 - 3.2 6.9 4.7 5 6.2 3.3 1.2 1 0 0 1 1 1 0 NOA36 protein EBV-NA3 PF05009.7 EPS34744.1 - 7.5 5.7 6.6 13 4.9 4.6 1.2 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Mg_trans_NIPA PF05653.9 EPS34745.1 - 2e-63 214.1 3.6 1.2e-59 201.7 1.9 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 EPS34745.1 - 9e-05 22.6 0.4 9e-05 22.6 0.3 3.5 3 1 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EPS34745.1 - 0.00085 19.3 2.5 0.00085 19.3 1.7 3.9 3 1 0 3 3 3 1 EamA-like transporter family ESSS PF10183.4 EPS34745.1 - 0.12 12.8 1.6 18 5.7 0.1 3.2 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Glyco_hydro_3 PF00933.16 EPS34746.1 - 2.8e-69 233.3 0.0 3.7e-69 232.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EPS34746.1 - 3.9e-62 209.7 0.0 6.9e-62 208.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EPS34746.1 - 5.5e-22 77.4 0.1 1.8e-21 75.8 0.1 2.0 1 0 0 1 1 1 1 Fibronectin type III-like domain Sugar-bind PF04198.8 EPS34746.1 - 0.021 13.7 0.0 0.04 12.8 0.0 1.4 1 0 0 1 1 1 0 Putative sugar-binding domain NAD_binding_10 PF13460.1 EPS34746.1 - 0.043 13.8 0.1 0.16 11.9 0.0 2.0 1 0 0 1 1 1 0 NADH(P)-binding Med30 PF11315.3 EPS34747.1 - 0.044 13.9 0.8 0.85 9.7 0.0 2.3 2 0 0 2 2 2 0 Mediator complex subunit 30 SCP-1 PF05483.7 EPS34747.1 - 0.074 10.8 0.2 0.13 10.0 0.1 1.2 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) DUF4140 PF13600.1 EPS34747.1 - 0.24 11.8 2.8 2.6 8.5 0.2 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Nsp1_C PF05064.8 EPS34747.1 - 0.26 10.9 2.6 0.45 10.1 0.1 2.3 2 0 0 2 2 2 0 Nsp1-like C-terminal region FlgN PF05130.7 EPS34747.1 - 1 9.6 8.0 2.9 8.1 0.4 2.7 3 0 0 3 3 3 0 FlgN protein HALZ PF02183.13 EPS34747.1 - 2.1 8.1 5.8 5.3 6.8 0.7 2.5 2 0 0 2 2 2 0 Homeobox associated leucine zipper bZIP_1 PF00170.16 EPS34747.1 - 2.3 8.2 8.1 9.4 6.2 0.7 2.6 2 0 0 2 2 2 0 bZIP transcription factor Striatin PF08232.7 EPS34747.1 - 2.9 8.1 8.5 4.2 7.6 3.0 3.1 2 1 0 2 2 2 0 Striatin family GRAM PF02893.15 EPS34748.1 - 3e-17 61.8 0.0 6.5e-17 60.8 0.0 1.6 1 0 0 1 1 1 1 GRAM domain Sugar_tr PF00083.19 EPS34749.1 - 1.6e-57 195.1 17.1 1.8e-57 194.9 11.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter Thioredoxin PF00085.15 EPS34750.1 - 5.6e-29 99.8 0.1 6.9e-29 99.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EPS34750.1 - 8.2e-10 38.6 0.1 4.8e-08 33.0 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EPS34750.1 - 3.1e-08 33.8 0.1 1.9e-07 31.2 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EPS34750.1 - 1.8e-06 27.8 0.1 3.8e-06 26.8 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 EPS34750.1 - 4.1e-06 26.4 0.0 5.2e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EPS34750.1 - 1.6e-05 24.4 0.2 0.0002 20.9 0.0 1.9 1 1 1 2 2 2 1 Redoxin TraF PF13728.1 EPS34750.1 - 0.0002 20.8 0.0 0.00028 20.4 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_9 PF14595.1 EPS34750.1 - 0.00044 19.8 0.0 0.00051 19.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_4 PF13462.1 EPS34750.1 - 0.011 15.7 0.4 0.17 11.9 0.1 2.0 1 1 1 2 2 2 0 Thioredoxin TrbC_Ftype PF09673.5 EPS34750.1 - 0.026 14.1 0.1 0.061 12.9 0.0 1.7 2 0 0 2 2 2 0 Type-F conjugative transfer system pilin assembly protein HyaE PF07449.6 EPS34750.1 - 0.072 12.9 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Hydrophobin PF01185.13 EPS34751.1 - 1.8e-13 50.7 7.4 2.6e-13 50.2 5.1 1.2 1 0 0 1 1 1 1 Fungal hydrophobin DUF2985 PF11204.3 EPS34752.1 - 1.1e-29 102.0 4.0 2.2e-29 101.0 2.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) SR-25 PF10500.4 EPS34753.1 - 2 7.8 22.5 2.9 7.2 15.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RRM_1 PF00076.17 EPS34754.1 - 1.3e-32 111.2 0.1 9.3e-16 57.2 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS34754.1 - 1.4e-23 82.6 0.0 1.1e-11 44.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS34754.1 - 8e-10 38.4 0.0 0.00083 19.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ArfGap PF01412.13 EPS34755.1 - 9.6e-32 109.2 0.1 1.7e-31 108.4 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf GTP_EFTU PF00009.22 EPS34756.1 - 2.7e-53 180.2 0.0 4e-53 179.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EPS34756.1 - 2.7e-25 88.0 0.1 8.4e-25 86.4 0.1 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 EPS34756.1 - 2.5e-16 59.2 0.0 4.2e-08 32.9 0.0 2.5 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EPS34756.1 - 3e-05 24.0 0.0 6.1e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EPS34756.1 - 0.022 14.6 0.0 0.049 13.5 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase EFG_IV PF03764.13 EPS34756.1 - 0.039 13.5 0.0 11 5.6 0.0 3.0 2 1 0 3 3 3 0 Elongation factor G, domain IV DUF2095 PF09868.4 EPS34756.1 - 0.11 12.2 0.1 0.27 10.9 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) FTHFS PF01268.14 EPS34756.1 - 0.13 10.1 0.0 0.2 9.6 0.0 1.1 1 0 0 1 1 1 0 Formate--tetrahydrofolate ligase Vps5 PF09325.5 EPS34757.1 - 1.2e-16 60.7 1.8 2e-16 59.9 1.2 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EPS34757.1 - 6.2e-11 42.0 0.0 1.3e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 PX domain Response_reg PF00072.19 EPS34758.1 - 5.8e-22 77.8 0.1 4.9e-21 74.8 0.1 2.4 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.21 EPS34758.1 - 5.4e-16 58.2 0.0 1.1e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EPS34758.1 - 5e-14 52.0 0.0 3.8e-13 49.2 0.0 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_3 PF13492.1 EPS34758.1 - 8.7e-05 22.6 0.1 0.0004 20.4 0.0 2.2 3 0 0 3 3 3 1 GAF domain GAF PF01590.21 EPS34758.1 - 0.00094 19.3 0.0 0.0033 17.5 0.0 2.0 1 0 0 1 1 1 1 GAF domain GAF_2 PF13185.1 EPS34758.1 - 0.005 17.3 0.0 0.014 15.8 0.0 1.8 1 0 0 1 1 1 1 GAF domain NmrA PF05368.8 EPS34760.1 - 1.1e-08 34.6 0.0 1.6e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 EPS34760.1 - 2.3e-08 34.3 0.0 4.1e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 EPS34760.1 - 4.1e-08 32.9 0.0 4.5e-05 23.0 0.1 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EPS34760.1 - 6.1e-06 26.3 0.0 9.6e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EPS34760.1 - 1.4e-05 24.1 0.1 3.6e-05 22.8 0.1 1.7 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 EPS34760.1 - 8.7e-05 21.3 0.0 0.00039 19.2 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EPS34760.1 - 0.00023 20.2 0.1 0.00033 19.7 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase RmlD_sub_bind PF04321.12 EPS34760.1 - 0.0031 16.4 0.0 0.14 11.0 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EPS34760.1 - 0.011 14.6 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DapB_N PF01113.15 EPS34760.1 - 0.037 13.9 0.0 0.065 13.1 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DXP_reductoisom PF02670.11 EPS34760.1 - 0.056 13.9 0.0 0.098 13.1 0.0 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Tho2 PF11262.3 EPS34761.1 - 2.7e-89 299.1 0.0 4.4e-89 298.4 0.0 1.3 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 EPS34761.1 - 2.4e-30 104.1 0.0 9.2e-30 102.2 0.0 2.1 2 0 0 2 2 2 1 Transcription- and export-related complex subunit Abhydrolase_1 PF00561.15 EPS34763.1 - 1.8e-43 148.7 0.0 4.2e-43 147.5 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EPS34763.1 - 2e-13 50.7 3.4 1.2e-12 48.2 2.4 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EPS34763.1 - 0.0025 17.5 0.0 0.34 10.6 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EPS34763.1 - 0.018 14.9 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Ribosomal_L7Ae PF01248.21 EPS34764.1 - 1.6e-25 88.4 0.0 1.8e-25 88.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SAP PF02037.22 EPS34765.1 - 9.7e-09 34.5 0.1 2e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 SAP domain RRM_5 PF13893.1 EPS34765.1 - 0.03 14.1 0.0 0.055 13.3 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Solute_trans_a PF03619.11 EPS34766.1 - 7.8e-88 294.3 20.3 9.2e-88 294.1 14.1 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha JAB PF01398.16 EPS34767.1 - 1.2e-08 34.6 0.0 3e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EPS34767.1 - 0.0045 17.0 0.4 0.041 13.9 0.3 2.3 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function Proteasom_PSMB PF10508.4 EPS34768.1 - 0.092 10.9 0.1 1.4 7.0 0.0 2.5 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit RNA_pol_3_Rpc31 PF11705.3 EPS34769.1 - 6.3e-56 189.9 13.2 7.1e-56 189.7 9.1 1.0 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Cwf_Cwc_15 PF04889.7 EPS34769.1 - 7.7 6.1 8.0 1.9 8.1 3.6 1.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein BUD22 PF09073.5 EPS34769.1 - 9.9 5.1 8.9 14 4.6 6.2 1.2 1 0 0 1 1 1 0 BUD22 Flavodoxin_1 PF00258.20 EPS34770.1 - 5.2e-32 110.8 0.0 1e-31 109.8 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.15 EPS34770.1 - 6.7e-30 104.1 0.0 1.1e-29 103.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EPS34770.1 - 1e-16 61.4 0.0 1e-15 58.2 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EPS34770.1 - 2.3e-05 24.4 0.0 0.0011 19.0 0.0 2.5 1 1 1 2 2 2 1 Flavodoxin domain Flavodoxin_3 PF12641.2 EPS34770.1 - 0.0077 15.6 0.0 0.044 13.2 0.0 2.0 2 0 0 2 2 2 1 Flavodoxin domain FAD_binding_6 PF00970.19 EPS34770.1 - 0.021 14.9 0.0 0.082 13.0 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain ETF PF01012.16 EPS34771.1 - 1.6e-35 122.2 0.3 2.1e-35 121.8 0.2 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain DUF500 PF04366.7 EPS34773.1 - 9.1e-44 147.9 0.0 2.3e-43 146.6 0.0 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF500) Fungal_trans_2 PF11951.3 EPS34775.1 - 5e-06 25.3 1.7 8.7e-05 21.2 0.2 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Trp_DMAT PF11991.3 EPS34776.1 - 1.5e-42 146.1 0.0 5e-42 144.3 0.0 1.7 2 0 0 2 2 2 1 Tryptophan dimethylallyltransferase Trp_DMAT PF11991.3 EPS34777.1 - 2.9e-11 43.1 0.1 3.1e-11 43.0 0.1 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase DUF707 PF05212.7 EPS34777.1 - 0.075 12.1 0.0 0.078 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF707) p450 PF00067.17 EPS34778.1 - 6.4e-58 196.3 0.0 9.4e-56 189.2 0.0 2.6 1 1 1 2 2 2 1 Cytochrome P450 NAD_binding_4 PF07993.7 EPS34779.1 - 1.7e-22 79.5 0.0 2.8e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Abhydrolase_3 PF07859.8 EPS34779.1 - 9.5e-16 58.0 0.0 4.4e-13 49.2 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold AMP-binding PF00501.23 EPS34779.1 - 1.8e-11 43.0 0.1 4.2e-05 22.1 0.0 2.6 1 1 1 2 2 2 2 AMP-binding enzyme Abhydrolase_5 PF12695.2 EPS34779.1 - 8.7e-10 38.5 0.0 1e-08 35.0 0.0 2.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Epimerase PF01370.16 EPS34779.1 - 1.5e-08 34.4 0.0 2.8e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Abhydrolase_6 PF12697.2 EPS34779.1 - 1.5e-07 31.5 5.3 1.3e-06 28.4 0.1 3.6 3 1 0 4 4 4 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EPS34779.1 - 1.2e-06 27.9 0.0 0.00074 18.7 0.0 2.5 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.13 EPS34779.1 - 0.003 16.8 0.0 0.54 9.4 0.0 2.3 2 0 0 2 2 2 1 Dienelactone hydrolase family Glyco_trans_1_4 PF13692.1 EPS34779.1 - 0.0034 17.5 0.1 0.14 12.2 0.0 2.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Abhydrolase_1 PF00561.15 EPS34779.1 - 0.011 15.3 0.5 8.3 5.8 0.0 3.3 3 1 1 4 4 4 0 alpha/beta hydrolase fold PP-binding PF00550.20 EPS34779.1 - 0.049 13.8 0.0 0.27 11.5 0.0 2.2 2 0 0 2 2 2 0 Phosphopantetheine attachment site Abhydrolase_2 PF02230.11 EPS34779.1 - 0.15 11.4 0.0 1.7 8.0 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Myb_DNA-binding PF00249.26 EPS34780.1 - 3.6e-30 103.7 8.7 3e-11 43.2 0.5 3.6 3 1 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EPS34780.1 - 2e-26 91.8 10.4 1.7e-10 40.8 0.5 3.8 1 1 2 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.3 EPS34780.1 - 0.0027 17.5 8.7 2.2 8.2 0.1 3.2 1 1 2 3 3 3 3 TRF2-interacting telomeric protein/Rap1 - C terminal domain MADF_DNA_bdg PF10545.4 EPS34780.1 - 0.021 14.9 6.0 0.073 13.2 0.2 2.7 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like BIR PF00653.16 EPS34780.1 - 0.056 13.8 2.6 0.12 12.8 0.6 2.2 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain DUF2508 PF10704.4 EPS34780.1 - 0.064 13.4 0.3 6.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) adh_short PF00106.20 EPS34781.1 - 6.2e-19 68.5 0.1 1.2e-18 67.6 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPS34781.1 - 1e-15 57.8 0.1 1.8e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Tmemb_14 PF03647.8 EPS34781.1 - 0.082 13.3 0.1 0.21 12.0 0.1 1.6 1 0 0 1 1 1 0 Transmembrane proteins 14C adh_short PF00106.20 EPS34782.1 - 1.3e-13 51.1 0.2 1.8e-13 50.7 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPS34782.1 - 8.5e-05 22.4 0.0 0.00013 21.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPS34782.1 - 0.00022 20.9 0.0 0.00037 20.2 0.0 1.3 1 0 0 1 1 1 1 KR domain ThiF PF00899.16 EPS34782.1 - 0.022 14.6 0.1 0.032 14.0 0.0 1.3 1 0 0 1 1 1 0 ThiF family Epimerase PF01370.16 EPS34782.1 - 0.035 13.5 0.0 0.054 12.9 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EPS34782.1 - 0.17 11.6 1.0 0.35 10.6 0.7 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase FAD_binding_4 PF01565.18 EPS34783.1 - 8.8e-21 73.8 0.5 1.5e-20 73.1 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EPS34783.1 - 0.00099 18.9 0.2 0.0024 17.7 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.17 EPS34784.1 - 1.4e-60 205.1 0.0 1.8e-60 204.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PARP PF00644.15 EPS34785.1 - 8.2e-11 41.7 0.2 3.3e-10 39.7 0.0 1.9 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain BRCT PF00533.21 EPS34785.1 - 0.00071 19.6 0.0 0.0018 18.4 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EPS34785.1 - 0.0043 16.8 0.0 0.012 15.3 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain PARP PF00644.15 EPS34786.1 - 3.1e-34 118.2 0.0 6.9e-34 117.0 0.0 1.6 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain BRCT PF00533.21 EPS34786.1 - 1.2e-07 31.7 0.0 3.2e-07 30.4 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EPS34786.1 - 0.00016 21.4 0.3 0.00031 20.5 0.2 1.6 1 0 0 1 1 1 1 twin BRCT domain NAD_binding_10 PF13460.1 EPS34787.1 - 2.5e-10 40.6 0.3 3.6e-10 40.1 0.2 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EPS34787.1 - 5.3e-05 22.5 0.4 0.00026 20.3 0.3 1.9 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EPS34787.1 - 6.8e-05 22.4 0.0 0.00022 20.7 0.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EPS34787.1 - 0.0041 16.0 0.0 0.19 10.6 0.0 2.3 1 1 1 2 2 2 1 Male sterility protein Semialdhyde_dh PF01118.19 EPS34787.1 - 0.073 13.3 0.0 0.2 11.9 0.0 1.8 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain HIM1 PF08732.5 EPS34787.1 - 0.088 11.2 0.0 0.45 8.9 0.0 1.8 1 1 0 2 2 2 0 HIM1 Peroxin-3 PF04882.7 EPS34788.1 - 2.8e-141 471.1 0.4 3.5e-141 470.8 0.3 1.1 1 0 0 1 1 1 1 Peroxin-3 DUF1649 PF07855.7 EPS34789.1 - 4.6e-64 215.0 0.0 5.2e-64 214.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) TB2_DP1_HVA22 PF03134.14 EPS34790.1 - 1.5e-30 104.7 6.8 2.1e-30 104.2 4.7 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Ras PF00071.17 EPS34791.1 - 4.4e-51 172.4 0.0 5.2e-51 172.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EPS34791.1 - 5.6e-21 75.2 0.0 8.3e-21 74.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EPS34791.1 - 4.2e-10 39.1 0.0 4.6e-10 39.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EPS34791.1 - 3.6e-06 26.5 0.0 3.3e-05 23.4 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EPS34791.1 - 1.2e-05 25.2 0.0 1.8e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EPS34791.1 - 0.0026 17.9 0.2 0.028 14.5 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EPS34791.1 - 0.085 12.8 0.5 0.49 10.3 0.3 2.2 1 1 1 2 2 2 0 AAA ATPase domain AAA_25 PF13481.1 EPS34791.1 - 0.15 11.4 0.1 0.4 10.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain Carboxyl_trans PF01039.17 EPS34792.1 - 1.4e-143 478.8 0.3 1.8e-143 478.4 0.2 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain Acyl-CoA_dh_1 PF00441.19 EPS34793.1 - 6.7e-41 139.8 1.0 1.1e-40 139.2 0.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EPS34793.1 - 1.4e-33 115.8 0.2 2.7e-33 114.8 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EPS34793.1 - 3.6e-21 74.3 0.3 7.1e-21 73.4 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EPS34793.1 - 1.2e-13 51.4 0.1 2.2e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EPS34793.1 - 9.5e-05 21.9 0.4 0.00053 19.4 0.3 2.0 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal FAD_binding_3 PF01494.14 EPS34794.1 - 5.3e-67 226.3 0.0 7e-67 225.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EPS34794.1 - 1.4e-31 109.4 0.0 2.1e-31 108.8 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox PF00070.22 EPS34794.1 - 0.00097 19.4 0.0 0.021 15.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 EPS34794.1 - 0.045 13.5 0.0 0.082 12.7 0.0 1.4 1 0 0 1 1 1 0 ThiF family NAD_binding_8 PF13450.1 EPS34794.1 - 0.045 13.7 0.1 0.16 11.9 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EPS34794.1 - 0.052 12.6 0.0 0.09 11.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 EPS34794.1 - 0.054 13.5 0.0 0.33 10.9 0.0 2.0 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPS34794.1 - 0.11 12.2 0.2 0.21 11.4 0.1 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Aminotran_1_2 PF00155.16 EPS34795.1 - 4.2e-13 48.9 0.0 5.7e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EPS34795.1 - 0.00013 20.6 0.0 0.00041 19.0 0.0 1.7 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase DOPA_dioxygen PF08883.6 EPS34796.1 - 2e-29 101.6 0.0 2.7e-29 101.2 0.0 1.2 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family Glyoxalase PF00903.20 EPS34797.1 - 8e-19 67.8 0.2 8.8e-13 48.3 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EPS34797.1 - 4.4e-12 45.9 0.0 5.4e-05 23.1 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EPS34797.1 - 5.5e-10 39.8 0.1 0.0018 18.8 0.1 2.5 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 EPS34797.1 - 1e-06 28.6 0.1 1.6e-05 24.8 0.0 2.6 3 0 0 3 3 3 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.1 EPS34797.1 - 0.00025 21.0 0.0 1.9 8.3 0.0 3.2 3 2 0 3 3 3 2 Glyoxalase-like domain FMN_dh PF01070.13 EPS34798.1 - 1.1e-105 353.4 0.0 1.4e-105 353.1 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EPS34798.1 - 2e-18 65.9 0.0 4.4e-18 64.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.20 EPS34798.1 - 0.00033 19.6 0.1 0.0073 15.2 0.0 2.4 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EPS34798.1 - 0.00039 19.6 0.0 0.00066 18.9 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.12 EPS34798.1 - 0.00043 19.3 0.0 0.00063 18.7 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.9 EPS34798.1 - 0.07 12.2 0.2 0.19 10.7 0.0 1.7 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG MFS_1 PF07690.11 EPS34800.1 - 5.8e-46 156.8 60.1 6.6e-42 143.4 32.4 3.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Pox_A14 PF05767.7 EPS34800.1 - 0.048 13.6 0.2 0.048 13.6 0.1 3.1 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 Sugar_tr PF00083.19 EPS34803.1 - 1.1e-108 363.7 26.6 1.5e-108 363.2 18.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS34803.1 - 3.7e-27 94.9 30.0 1.2e-20 73.5 6.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Amidohydro_1 PF01979.15 EPS34804.1 - 2.1e-18 67.1 0.1 4.5e-17 62.7 0.1 2.2 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EPS34804.1 - 5.8e-15 54.8 0.0 2.2e-14 52.9 0.0 2.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EPS34804.1 - 8.8e-14 52.1 0.1 8.6e-06 25.9 0.0 2.8 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 EPS34804.1 - 2.6e-07 30.2 0.4 0.0036 16.5 0.0 3.0 2 1 0 2 2 2 2 Amidohydrolase family CPSase_L_D2 PF02786.12 EPS34805.1 - 5.6e-73 244.7 0.0 1e-72 243.8 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 EPS34805.1 - 2.4e-35 120.7 0.0 6.8e-35 119.2 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 EPS34805.1 - 3.4e-33 114.0 0.0 9.5e-33 112.5 0.0 1.8 2 0 0 2 2 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EPS34805.1 - 9e-19 67.9 0.0 2.5e-18 66.4 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EPS34805.1 - 5.5e-18 64.3 0.3 2.3e-17 62.3 0.2 2.2 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 EPS34805.1 - 2.2e-09 36.9 0.0 5.1e-09 35.8 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EPS34805.1 - 2e-07 30.5 0.0 3.9e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EPS34805.1 - 7.4e-07 28.7 0.1 0.0026 17.3 0.0 2.8 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.9 EPS34805.1 - 7e-05 22.7 0.0 0.00014 21.7 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 EPS34805.1 - 0.00018 21.8 0.1 0.27 11.5 0.0 2.8 2 0 0 2 2 2 2 HlyD family secretion protein GARS_A PF01071.14 EPS34805.1 - 0.0045 16.5 0.0 0.0078 15.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.6 EPS34805.1 - 0.006 16.0 0.0 0.045 13.2 0.0 2.2 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.1 EPS34805.1 - 0.029 13.4 0.1 0.07 12.2 0.0 1.7 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp GCV_H PF01597.14 EPS34805.1 - 0.039 13.6 0.0 0.094 12.3 0.0 1.6 1 0 0 1 1 1 0 Glycine cleavage H-protein adh_short_C2 PF13561.1 EPS34806.1 - 2.1e-26 93.1 0.0 2.7e-26 92.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EPS34806.1 - 4.7e-22 78.6 0.3 6.3e-22 78.2 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPS34806.1 - 1.9e-12 47.2 0.1 2.8e-12 46.6 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPS34806.1 - 0.011 15.1 0.2 0.038 13.4 0.1 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family MARVEL PF01284.18 EPS34807.1 - 3.3e-06 26.9 2.6 3.3e-06 26.9 1.8 1.9 2 1 0 2 2 2 1 Membrane-associating domain DUF2834 PF11196.3 EPS34807.1 - 0.034 14.3 0.7 1.5 9.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2834) DDA1 PF10172.4 EPS34808.1 - 0.14 11.9 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Det1 complexing ubiquitin ligase PHD PF00628.24 EPS34810.1 - 5e-10 38.9 2.1 1.3e-09 37.6 1.5 1.7 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EPS34810.1 - 0.016 14.5 2.7 0.026 13.8 1.9 1.3 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.17 EPS34810.1 - 1.1 9.0 4.1 1.2 8.9 0.3 2.2 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Rep_fac-A_C PF08646.5 EPS34810.1 - 2.7 7.6 4.4 2.6 7.7 0.1 2.3 2 0 0 2 2 2 0 Replication factor-A C terminal domain eIF-5a PF01287.15 EPS34811.1 - 0.00012 21.9 0.0 0.00024 20.9 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Abhydrolase_6 PF12697.2 EPS34814.1 - 4.1e-26 92.2 3.4 2.1e-25 89.9 2.3 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPS34814.1 - 1.2e-10 41.3 0.0 2e-09 37.3 0.0 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPS34814.1 - 4.6e-10 39.4 0.1 1.2e-09 38.0 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EPS34814.1 - 1.8e-09 37.3 0.0 1.1e-08 34.7 0.0 2.4 2 1 0 2 2 2 1 Putative lysophospholipase Esterase_phd PF10503.4 EPS34814.1 - 4.4e-05 22.8 0.1 9.2e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase Esterase PF00756.15 EPS34814.1 - 0.00022 20.7 0.0 0.00052 19.5 0.0 1.5 1 1 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.2 EPS34814.1 - 0.034 13.0 0.0 0.059 12.2 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.6 EPS34814.1 - 0.13 11.0 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase SET PF00856.23 EPS34815.1 - 7.5e-12 45.8 0.1 3.4e-11 43.7 0.1 2.0 1 1 0 1 1 1 1 SET domain SRR1 PF07985.7 EPS34818.1 - 5.5e-12 45.4 0.0 1.2e-11 44.3 0.0 1.6 1 1 0 1 1 1 1 SRR1 RRP7 PF12923.2 EPS34818.1 - 0.014 15.4 0.5 0.014 15.4 0.3 1.6 2 0 0 2 2 2 0 Ribosomal RNA-processing protein 7 (RRP7) Glyco_hydro_17 PF00332.13 EPS34819.1 - 1.5e-07 30.8 3.0 2.7e-05 23.3 0.2 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 zf-DHHC PF01529.15 EPS34828.1 - 8.5e-27 93.6 5.8 8.5e-27 93.6 4.0 2.3 2 1 1 3 3 3 1 DHHC palmitoyltransferase DUF2177 PF09945.4 EPS34828.1 - 0.49 10.3 0.1 0.49 10.3 0.0 2.8 3 0 0 3 3 3 0 Predicted membrane protein (DUF2177) DUF4131 PF13567.1 EPS34828.1 - 2.4 7.5 5.6 1.5 8.2 2.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Zn_clus PF00172.13 EPS34832.1 - 2.3e-08 33.7 6.5 6.3e-08 32.3 4.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_N PF08240.7 EPS34833.1 - 2.1e-05 24.2 0.0 0.00022 20.9 0.0 2.3 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EPS34833.1 - 0.00024 20.6 0.0 0.00043 19.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase zf-C3H1 PF10650.4 EPS34834.1 - 2.3e-12 46.1 3.1 3.6e-12 45.5 2.2 1.3 1 0 0 1 1 1 1 Putative zinc-finger domain SPT16 PF08644.6 EPS34834.1 - 0.074 12.8 3.2 1.5 8.6 0.1 3.0 3 0 0 3 3 3 0 FACT complex subunit (SPT16/CDC68) Myosin_head PF00063.16 EPS34835.1 - 5.8e-247 821.1 0.0 5.8e-247 821.1 0.0 2.1 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 EPS34835.1 - 3.3e-31 107.8 290.8 4.1e-25 87.7 56.9 6.1 1 1 4 5 5 5 3 Myosin tail Myosin_N PF02736.14 EPS34835.1 - 0.00019 21.0 0.0 0.00052 19.6 0.0 1.7 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_19 PF13245.1 EPS34835.1 - 0.073 12.8 0.0 0.23 11.2 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain Isy1 PF06246.7 EPS34836.1 - 7.1e-87 291.0 0.1 8.8e-87 290.7 0.1 1.1 1 0 0 1 1 1 1 Isy1-like splicing family YolD PF08863.5 EPS34836.1 - 0.058 13.2 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 YolD-like protein MMR_HSR1 PF01926.18 EPS34837.1 - 4e-12 46.0 0.0 1.1e-11 44.6 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EPS34837.1 - 0.00012 21.4 0.0 0.00018 20.7 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.11 EPS34837.1 - 0.00056 19.0 0.0 0.00089 18.4 0.0 1.3 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 EPS34837.1 - 0.0016 17.6 0.0 0.0027 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MobB PF03205.9 EPS34837.1 - 0.011 15.4 0.1 0.028 14.1 0.1 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Septin PF00735.13 EPS34837.1 - 0.024 13.6 0.0 0.042 12.8 0.0 1.3 1 0 0 1 1 1 0 Septin Dynamin_N PF00350.18 EPS34837.1 - 0.036 13.8 0.1 0.63 9.8 0.0 2.5 1 1 1 2 2 2 0 Dynamin family AAA_16 PF13191.1 EPS34837.1 - 0.11 12.5 0.1 0.43 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain HCO3_cotransp PF00955.16 EPS34838.1 - 8.1e-49 166.6 19.5 3.9e-28 98.3 1.2 2.1 1 1 1 2 2 2 2 HCO3- transporter family ASFV_J13L PF05568.6 EPS34838.1 - 0.0055 16.2 0.3 0.012 15.1 0.2 1.5 1 0 0 1 1 1 1 African swine fever virus J13L protein PI3Ka PF00613.15 EPS34839.1 - 9.3e-61 204.2 0.2 1.5e-60 203.5 0.1 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EPS34839.1 - 9.2e-43 146.3 0.0 3.7e-41 141.1 0.0 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 EPS34839.1 - 4.3e-25 88.1 0.0 7.3e-25 87.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Nse4_C PF08743.5 EPS34840.1 - 1.8e-28 98.4 0.0 3.8e-28 97.3 0.0 1.6 1 0 0 1 1 1 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 EPS34840.1 - 1.2e-18 66.7 0.1 3.9e-18 65.0 0.0 2.0 2 0 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE DUF4336 PF14234.1 EPS34841.1 - 2.2e-17 63.1 0.0 5.8e-14 51.9 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4336) MARVEL PF01284.18 EPS34842.1 - 2.8e-09 36.9 7.2 3.8e-09 36.5 5.0 1.2 1 0 0 1 1 1 1 Membrane-associating domain LCCL PF03815.14 EPS34843.1 - 1.9e-20 72.6 0.0 3.4e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 LCCL domain Metallophos PF00149.23 EPS34844.1 - 2.5e-09 36.8 0.6 1.2e-08 34.5 0.4 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EPS34844.1 - 3.4e-07 30.2 0.3 5.6e-07 29.5 0.2 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ThiF PF00899.16 EPS34845.1 - 1.1e-35 122.4 0.0 2.9e-35 121.0 0.0 1.7 2 0 0 2 2 2 1 ThiF family ApbA PF02558.11 EPS34845.1 - 0.0072 15.7 0.1 0.013 14.9 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 EPS34845.1 - 0.0094 15.9 0.0 0.025 14.5 0.0 1.8 1 0 0 1 1 1 1 TrkA-N domain KR PF08659.5 EPS34845.1 - 0.014 15.0 0.1 0.03 13.9 0.1 1.6 1 0 0 1 1 1 0 KR domain NAD_binding_7 PF13241.1 EPS34845.1 - 0.041 14.1 0.0 0.14 12.4 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding DAO PF01266.19 EPS34845.1 - 0.044 12.6 0.1 0.096 11.5 0.1 1.6 1 0 0 1 1 1 0 FAD dependent oxidoreductase RHH_1 PF01402.16 EPS34845.1 - 0.044 13.6 0.1 0.11 12.3 0.1 1.7 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family Saccharop_dh PF03435.13 EPS34845.1 - 0.05 12.5 0.6 0.22 10.4 0.4 1.9 1 1 0 1 1 1 0 Saccharopine dehydrogenase UDPG_MGDP_dh_N PF03721.9 EPS34845.1 - 0.07 12.4 0.1 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EPS34845.1 - 0.091 12.4 0.0 0.19 11.3 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EPS34845.1 - 0.14 11.9 0.1 0.63 9.7 0.0 2.0 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Abhydrolase_1 PF00561.15 EPS34846.1 - 2.3e-17 63.3 0.0 1.5e-16 60.6 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EPS34846.1 - 1.8e-11 44.3 0.9 5.6e-10 39.4 0.6 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EPS34846.1 - 0.00047 19.6 0.0 0.00092 18.7 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Glyco_hydro_43 PF04616.9 EPS34847.1 - 2.1e-32 112.3 0.0 9.8e-32 110.1 0.0 1.8 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 EPS34847.1 - 0.0018 17.7 0.1 0.03 13.6 0.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 N-terminal domain DUF377 PF04041.8 EPS34847.1 - 0.19 10.4 0.0 2.2 6.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF377) Gly_transf_sug PF04488.10 EPS34848.1 - 8.7e-13 48.5 0.0 1.7e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Pkinase PF00069.20 EPS34849.1 - 1.4e-62 211.1 0.0 1.7e-62 210.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS34849.1 - 2.7e-36 124.9 0.0 3.4e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EPS34849.1 - 0.0022 17.0 0.0 0.0051 15.8 0.0 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EPS34849.1 - 0.0044 16.0 0.0 0.0068 15.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EPS34849.1 - 0.01 15.5 0.0 0.19 11.3 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EPS34849.1 - 0.05 12.4 0.0 0.078 11.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 ATP-synt_C PF00137.16 EPS34850.1 - 4.9e-27 93.6 30.2 5e-15 55.1 6.7 2.0 2 0 0 2 2 2 2 ATP synthase subunit C Polysacc_synt_3 PF13440.1 EPS34850.1 - 0.0044 16.5 1.8 0.0044 16.5 1.2 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein CNH PF00780.17 EPS34852.1 - 2.2e-84 283.1 0.0 1.1e-83 280.8 0.0 1.9 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 EPS34852.1 - 4.2e-42 143.2 0.0 1.2e-41 141.7 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 EPS34852.1 - 4.7e-39 134.1 0.0 9.2e-39 133.1 0.0 1.5 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 EPS34852.1 - 6.8e-14 51.3 0.0 1.9e-13 49.9 0.0 1.8 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) YorP PF09629.5 EPS34852.1 - 0.044 13.7 0.1 18 5.4 0.0 2.6 2 0 0 2 2 2 0 YorP protein Septin PF00735.13 EPS34854.1 - 5.6e-105 350.3 0.1 9.9e-105 349.5 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EPS34854.1 - 0.00016 21.6 0.0 0.00036 20.4 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_17 PF13207.1 EPS34854.1 - 0.0071 17.1 1.8 0.15 12.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 EPS34854.1 - 0.0081 15.3 0.4 0.028 13.6 0.3 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EPS34854.1 - 0.018 14.4 0.0 0.51 9.7 0.0 2.2 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Miro PF08477.8 EPS34854.1 - 0.032 14.7 0.0 0.1 13.1 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein AAA_22 PF13401.1 EPS34854.1 - 0.099 12.7 0.1 0.37 10.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EPS34854.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 EPS34854.1 - 0.15 11.8 5.3 2 8.1 0.0 2.9 2 1 1 3 3 3 0 Dynamin family DUF3653 PF12375.3 EPS34854.1 - 0.43 10.8 2.8 7.8 6.8 1.1 2.7 2 1 0 2 2 2 0 Phage protein WD40 PF00400.27 EPS34855.1 - 5.6e-09 35.5 0.0 0.0031 17.3 0.0 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EPS34855.1 - 0.0069 15.8 0.0 1.5 8.3 0.0 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.7 EPS34855.1 - 0.017 12.9 0.0 0.03 12.1 0.0 1.3 1 1 0 1 1 1 0 IKI3 family DUF2415 PF10313.4 EPS34855.1 - 0.11 12.1 0.3 0.55 9.9 0.1 2.2 3 0 0 3 3 3 0 Uncharacterised protein domain (DUF2415) RRM_1 PF00076.17 EPS34856.1 - 2e-18 65.7 0.0 4.1e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS34856.1 - 2.5e-12 46.5 0.0 4.7e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS34856.1 - 3.8e-07 29.8 0.0 6e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DLIC PF05783.6 EPS34857.1 - 7.5e-39 133.6 1.1 7.4e-35 120.5 0.0 3.2 2 1 0 2 2 2 2 Dynein light intermediate chain (DLIC) Spermine_synth PF01564.12 EPS34858.1 - 3.8e-10 39.1 0.0 6e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_26 PF13659.1 EPS34858.1 - 1.9e-05 24.6 0.0 3.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EPS34858.1 - 0.00096 19.7 0.0 0.0017 18.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EPS34858.1 - 0.0022 17.7 0.0 0.0043 16.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_30 PF05430.6 EPS34858.1 - 0.03 13.9 0.0 0.057 13.0 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine-dependent methyltransferase DUF2052 PF09747.4 EPS34859.1 - 4.7e-34 117.9 11.9 1.6e-33 116.1 8.3 1.7 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) AMP-binding PF00501.23 EPS34860.1 - 7.7e-95 317.7 0.0 9.6e-95 317.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPS34860.1 - 4.1e-15 56.4 0.0 1.1e-14 55.1 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Adap_comp_sub PF00928.16 EPS34861.1 - 4.6e-90 301.2 0.0 6.2e-90 300.8 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EPS34861.1 - 1.2e-08 34.8 0.2 1.9e-08 34.1 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 EPS34861.1 - 0.079 12.1 0.0 0.25 10.5 0.0 1.7 2 0 0 2 2 2 0 Muniscin C-terminal mu homology domain Ribonucleas_3_3 PF14622.1 EPS34862.1 - 1.2e-27 96.3 0.0 2.1e-27 95.5 0.0 1.4 1 1 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EPS34862.1 - 0.00016 22.1 0.0 0.00035 21.0 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain Sdh_cyt PF01127.17 EPS34864.1 - 3.5e-24 84.9 4.3 4.4e-24 84.6 3.0 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit NMO PF03060.10 EPS34865.1 - 2.1e-61 207.9 0.1 3.5e-61 207.1 0.0 1.3 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EPS34865.1 - 1.2e-10 40.7 0.0 0.00027 19.9 0.1 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EPS34865.1 - 0.0036 16.2 0.1 0.0062 15.4 0.1 1.4 1 0 0 1 1 1 1 FMN-dependent dehydrogenase DUF1902 PF08972.6 EPS34865.1 - 0.023 14.2 0.0 0.05 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1902) Glu_synthase PF01645.12 EPS34865.1 - 0.068 12.0 0.6 0.21 10.4 0.1 1.8 1 1 1 2 2 2 0 Conserved region in glutamate synthase NanE PF04131.9 EPS34865.1 - 0.09 11.7 0.0 0.16 10.9 0.0 1.5 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Tad PF13400.1 EPS34867.1 - 0.073 13.1 2.3 0.14 12.1 1.6 1.4 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like Hydrophobin PF01185.13 EPS34868.1 - 3.8e-15 56.0 7.7 5.5e-15 55.5 5.3 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Trp_leader1 PF08055.6 EPS34869.1 - 0.16 11.5 1.0 0.41 10.1 0.7 1.7 1 0 0 1 1 1 0 Tryptophan leader peptide WW PF00397.21 EPS34870.1 - 2.2e-07 30.6 0.3 5.3e-07 29.3 0.2 1.7 1 0 0 1 1 1 1 WW domain Ank_2 PF12796.2 EPS34871.1 - 2.8e-14 53.2 0.9 6e-14 52.1 0.5 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EPS34871.1 - 2.1e-13 49.3 0.3 9.7e-11 40.9 0.1 3.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 EPS34871.1 - 4.7e-12 46.0 0.6 2.9e-06 27.6 0.1 2.8 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EPS34871.1 - 8.2e-10 38.6 1.2 2.9e-07 30.5 0.4 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EPS34871.1 - 2.3e-09 36.6 0.1 1.4e-07 31.0 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ribosomal_60s PF00428.14 EPS34871.1 - 1.8 9.0 11.3 0.68 10.3 5.6 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein Glyco_transf_21 PF13506.1 EPS34872.1 - 6.2e-12 45.1 0.0 2.8e-05 23.4 0.0 3.4 3 1 0 3 3 3 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 EPS34872.1 - 2.1e-09 37.5 0.0 5.3e-09 36.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EPS34872.1 - 0.0028 17.3 0.0 0.012 15.3 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 KAT11 PF08214.6 EPS34873.1 - 6.9e-102 341.0 0.0 1e-101 340.5 0.0 1.2 1 0 0 1 1 1 1 Histone acetylation protein DUF4452 PF14618.1 EPS34873.1 - 0.0081 15.9 0.4 0.023 14.5 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4452) Hid1 PF12722.2 EPS34876.1 - 2.7e-268 892.3 0.0 4.6e-268 891.5 0.0 1.3 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 EPS34876.1 - 5.4e-79 266.0 0.0 8.4e-79 265.4 0.0 1.2 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein NPCC PF08058.6 EPS34877.1 - 5.3e-34 117.1 0.4 3e-32 111.4 0.2 2.2 1 1 0 1 1 1 1 Nuclear pore complex component AMP-binding PF00501.23 EPS34878.1 - 4.9e-11 41.6 0.3 8.9e-08 30.9 0.0 2.3 2 1 0 2 2 2 2 AMP-binding enzyme ATHILA PF03078.10 EPS34878.1 - 0.037 12.6 0.0 0.054 12.0 0.0 1.1 1 0 0 1 1 1 0 ATHILA ORF-1 family Ribosomal_L19 PF01245.15 EPS34880.1 - 3.5e-19 68.6 1.0 5.8e-19 67.9 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L19 RasGEF_N_2 PF14663.1 EPS34881.1 - 0.015 15.2 0.5 0.073 13.0 0.1 2.1 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain GTPase_Cys_C PF12631.2 EPS34881.1 - 0.032 14.6 0.6 0.094 13.1 0.1 1.9 2 0 0 2 2 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE ABC_tran PF00005.22 EPS34882.1 - 2.3e-49 167.2 0.1 3.6e-25 88.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 EPS34882.1 - 1.8e-24 86.4 40.5 2e-16 59.9 14.5 2.7 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 EPS34882.1 - 2.2e-21 77.1 0.1 7.9e-05 22.7 0.0 4.3 3 1 0 4 4 4 4 AAA domain AAA_29 PF13555.1 EPS34882.1 - 9e-09 34.7 3.5 0.00012 21.4 0.9 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 EPS34882.1 - 9.9e-09 34.7 0.0 0.039 13.1 0.0 4.0 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EPS34882.1 - 1.2e-07 32.2 1.2 0.0095 16.2 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EPS34882.1 - 0.00044 20.2 0.8 1.2 9.0 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 EPS34882.1 - 0.0043 16.4 1.6 2.3 7.6 0.1 3.2 3 1 0 3 3 3 2 AAA domain AAA_15 PF13175.1 EPS34882.1 - 0.0046 16.0 0.0 3.1 6.7 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain SbcCD_C PF13558.1 EPS34882.1 - 0.0085 15.9 0.3 8.5 6.3 0.0 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit SRP54 PF00448.17 EPS34882.1 - 0.0089 15.4 1.0 1 8.7 0.0 2.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_22 PF13401.1 EPS34882.1 - 0.022 14.8 0.1 8.1 6.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EPS34882.1 - 0.031 13.8 3.7 7.6 6.0 0.2 3.5 4 0 0 4 4 4 0 AAA domain Zeta_toxin PF06414.7 EPS34882.1 - 0.038 13.0 3.3 1.7 7.7 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin AAA_28 PF13521.1 EPS34882.1 - 0.041 13.8 1.4 9.5 6.1 0.6 2.5 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EPS34882.1 - 0.052 12.7 7.2 0.76 8.9 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function, DUF258 AAA_19 PF13245.1 EPS34882.1 - 0.057 13.1 4.9 2.8 7.7 0.0 3.2 3 0 0 3 3 3 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 EPS34882.1 - 0.1 12.0 0.6 0.36 10.2 0.0 2.1 3 0 0 3 3 2 0 FtsK/SpoIIIE family UPF0079 PF02367.12 EPS34882.1 - 0.21 11.1 1.0 6.6 6.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 EPS34882.1 - 0.43 10.4 2.5 22 4.8 0.2 3.1 3 0 0 3 3 3 0 AAA domain AAA_13 PF13166.1 EPS34882.1 - 0.45 8.9 0.4 10 4.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.11 EPS34883.1 - 1.8e-33 115.7 25.6 2.7e-33 115.1 17.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily ABC2_membrane PF01061.19 EPS34884.1 - 1.2e-86 289.2 58.2 4.8e-45 153.3 11.2 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EPS34884.1 - 2.3e-34 118.6 1.2 2.2e-17 63.6 0.0 3.1 4 0 0 4 4 3 2 ABC transporter PDR_CDR PF06422.7 EPS34884.1 - 3.5e-25 87.6 0.2 8.3e-21 73.5 0.0 3.0 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 EPS34884.1 - 4.9e-09 35.6 41.2 0.00015 20.9 6.1 2.8 2 1 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 EPS34884.1 - 2.8e-07 30.4 0.1 9.3e-07 28.8 0.0 1.9 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_33 PF13671.1 EPS34884.1 - 1.3e-05 25.1 0.0 0.00073 19.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EPS34884.1 - 1.8e-05 24.8 0.3 0.088 12.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EPS34884.1 - 2.3e-05 23.8 0.0 0.0036 16.7 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EPS34884.1 - 2.9e-05 24.8 0.0 0.015 16.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EPS34884.1 - 0.00036 19.9 0.4 0.0035 16.8 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 EPS34884.1 - 0.00051 19.5 0.1 0.005 16.3 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 EPS34884.1 - 0.00054 19.9 0.2 0.026 14.4 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 EPS34884.1 - 0.00085 18.5 0.0 0.0037 16.4 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_19 PF13245.1 EPS34884.1 - 0.0016 18.1 0.4 2.9 7.7 0.3 2.6 2 0 0 2 2 2 2 Part of AAA domain AAA_22 PF13401.1 EPS34884.1 - 0.0016 18.5 0.1 0.25 11.4 0.0 2.9 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 EPS34884.1 - 0.0049 16.1 0.2 0.6 9.2 0.0 3.0 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.1 EPS34884.1 - 0.0063 16.4 0.1 0.034 14.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EPS34884.1 - 0.0081 16.4 0.0 0.24 11.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EPS34884.1 - 0.018 14.6 0.8 0.97 9.0 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PduV-EutP PF10662.4 EPS34884.1 - 0.036 13.5 0.2 2 7.8 0.1 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 EPS34884.1 - 0.058 13.0 0.3 5.5 6.6 0.2 2.5 2 0 0 2 2 2 0 NACHT domain Miro PF08477.8 EPS34884.1 - 0.085 13.3 0.3 14 6.1 0.0 3.0 3 0 0 3 3 2 0 Miro-like protein Arch_ATPase PF01637.13 EPS34884.1 - 0.099 12.3 0.0 9.1 5.9 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase AAA PF00004.24 EPS34884.1 - 0.14 12.3 0.0 29 4.8 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.1 EPS34884.1 - 0.16 11.0 0.0 0.98 8.3 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.1 EPS34884.1 - 0.41 10.9 0.0 0.41 10.9 0.0 2.4 3 0 0 3 3 2 0 AAA domain Opi1 PF08618.5 EPS34885.1 - 5.2e-95 318.8 1.1 6.3e-55 186.8 1.2 3.8 1 1 2 3 3 3 3 Transcription factor Opi1 RdRP PF05183.7 EPS34886.1 - 1.6e-119 400.2 0.0 2.7e-119 399.4 0.0 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase AA_permease PF00324.16 EPS34887.1 - 4.8e-62 209.8 34.4 6e-62 209.5 23.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EPS34887.1 - 1.1e-13 50.5 35.7 1.5e-13 50.0 24.8 1.1 1 0 0 1 1 1 1 Amino acid permease PIRT PF15099.1 EPS34887.1 - 0.58 9.3 3.5 1.6 7.9 2.4 1.7 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family COX14 PF14880.1 EPS34887.1 - 6.2 6.5 7.4 9.7 5.9 1.3 3.5 3 0 0 3 3 3 0 Cytochrome oxidase c assembly NmrA PF05368.8 EPS34888.1 - 5.8e-31 107.5 0.0 7.2e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EPS34888.1 - 3.3e-12 46.7 0.0 5.1e-12 46.1 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EPS34888.1 - 0.00027 20.0 0.1 0.00037 19.5 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 EPS34888.1 - 0.00089 19.5 0.1 0.0015 18.7 0.1 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EPS34888.1 - 0.01 15.9 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase KR PF08659.5 EPS34888.1 - 0.15 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 KR domain DapB_N PF01113.15 EPS34888.1 - 0.16 11.9 0.1 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF2109 PF09882.4 EPS34889.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2109) FERM_M PF00373.13 EPS34891.1 - 0.0044 17.1 0.1 0.0068 16.5 0.1 1.3 1 0 0 1 1 1 1 FERM central domain DUF4581 PF15167.1 EPS34892.1 - 0.13 12.1 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4581) Voldacs PF03517.8 EPS34894.1 - 3.9e-32 110.9 0.1 3.9e-32 110.9 0.1 1.9 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling CENP-T PF15511.1 EPS34894.1 - 0.32 10.2 9.4 0.012 14.8 2.3 1.7 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T Metallophos PF00149.23 EPS34896.1 - 8.4e-42 142.8 0.4 1.2e-41 142.2 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPT PF03151.11 EPS34898.1 - 1.2e-25 89.9 6.6 1.2e-25 89.9 4.6 2.8 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EPS34898.1 - 1.6e-07 30.5 23.0 3.4e-07 29.4 15.9 1.5 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EPS34898.1 - 6.5e-07 29.4 32.9 0.00026 21.0 4.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family DUF3325 PF11804.3 EPS34898.1 - 7.3 6.5 10.3 0.11 12.4 0.4 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF3325) Glyco_transf_25 PF01755.12 EPS34900.1 - 6.9e-11 42.1 0.2 3e-07 30.3 0.2 2.5 2 1 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) Trypan_PARP PF05887.6 EPS34900.1 - 0.54 10.0 12.4 1 9.1 8.6 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF1996 PF09362.5 EPS34901.1 - 8.3e-80 267.8 0.7 1.8e-79 266.7 0.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1996) Aldo_ket_red PF00248.16 EPS34902.1 - 8.9e-71 237.9 0.0 1.1e-70 237.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family adh_short PF00106.20 EPS34903.1 - 2.9e-31 108.6 0.2 3.6e-31 108.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPS34903.1 - 9.6e-31 107.3 0.0 1.2e-30 107.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPS34903.1 - 3.6e-08 33.2 0.1 5.8e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EPS34903.1 - 3.6e-05 23.3 0.1 7.1e-05 22.3 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EPS34903.1 - 0.042 13.6 1.2 0.076 12.8 0.8 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EPS34903.1 - 0.11 12.4 0.4 0.21 11.5 0.3 1.5 1 1 0 1 1 1 0 NADH(P)-binding Fungal_trans_2 PF11951.3 EPS34904.1 - 2.4e-37 128.4 0.1 5.2e-37 127.3 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS34904.1 - 4.1e-09 36.2 7.9 7e-09 35.4 5.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease_2 PF13520.1 EPS34905.1 - 3.2e-41 141.2 46.7 4.4e-41 140.8 32.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EPS34905.1 - 5.4e-19 67.8 39.6 7.3e-19 67.4 27.4 1.1 1 0 0 1 1 1 1 Amino acid permease PNTB PF02233.11 EPS34906.1 - 1.7e-165 551.2 25.7 3.1e-165 550.4 17.8 1.4 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 EPS34906.1 - 2.7e-54 183.2 0.5 5.4e-54 182.2 0.3 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 EPS34906.1 - 2.3e-45 153.9 0.1 6.2e-45 152.5 0.0 1.8 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 EPS34906.1 - 3.2e-31 107.3 3.8 3.2e-31 107.3 2.6 5.2 5 0 0 5 5 5 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 EPS34906.1 - 0.00016 20.8 0.2 0.56 9.3 0.0 3.2 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TPP_enzyme_M PF00205.17 EPS34906.1 - 0.003 17.3 0.5 0.015 15.0 0.4 2.2 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Methyltransf_31 PF13847.1 EPS34906.1 - 0.039 13.5 0.0 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Pyr_redox_2 PF07992.9 EPS34906.1 - 0.039 13.8 0.6 0.084 12.7 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_18 PF12847.2 EPS34906.1 - 0.059 13.9 0.0 0.19 12.3 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Shikimate_DH PF01488.15 EPS34906.1 - 0.077 13.0 5.7 4.6 7.3 0.0 4.6 4 1 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 EPS34906.1 - 0.81 9.7 4.3 0.43 10.6 0.3 2.6 3 0 0 3 3 2 0 NAD(P)-binding Rossmann-like domain DUF863 PF05904.6 EPS34906.1 - 1.7 6.8 0.6 2.3 6.3 0.4 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF863) Pkinase PF00069.20 EPS34909.1 - 0.0007 18.8 0.0 0.00075 18.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain ELO PF01151.13 EPS34911.1 - 5.9e-62 209.2 25.0 6.9e-62 208.9 17.3 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family COX5A PF02284.11 EPS34912.1 - 4.8e-39 132.6 0.3 6.4e-39 132.2 0.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va LOH1CR12 PF10158.4 EPS34912.1 - 0.018 14.8 0.2 3.6 7.3 0.1 2.2 1 1 1 2 2 2 0 Tumour suppressor protein P21-Arc PF04062.9 EPS34912.1 - 0.14 11.9 0.1 0.2 11.4 0.1 1.3 1 0 0 1 1 1 0 ARP2/3 complex ARPC3 (21 kDa) subunit Glyco_transf_15 PF01793.11 EPS34913.1 - 7.2e-138 459.0 9.6 8.5e-138 458.8 6.6 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Spc97_Spc98 PF04130.8 EPS34914.1 - 5.8e-62 209.7 5.7 5.8e-62 209.7 3.9 1.8 2 0 0 2 2 2 1 Spc97 / Spc98 family GCP5-Mod21 PF14609.1 EPS34914.1 - 1.3e-08 33.4 0.0 1.3e-08 33.4 0.0 1.6 2 0 0 2 2 2 1 gamma-Tubulin ring complex non-core subunit mod21 GATase_5 PF13507.1 EPS34915.1 - 3.1e-96 321.2 0.0 5.1e-96 320.5 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 EPS34915.1 - 9e-44 149.1 0.3 1.7e-21 76.8 0.1 2.5 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EPS34915.1 - 1.9e-26 92.1 0.1 2.5e-25 88.5 0.0 2.6 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain MFS_1 PF07690.11 EPS34916.1 - 2e-39 135.3 30.7 2e-39 135.3 21.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EPS34916.1 - 4.9e-11 41.8 11.7 4.9e-11 41.8 8.1 2.5 2 2 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EPS34916.1 - 8.6e-08 30.8 1.8 1.4e-07 30.0 1.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2178 PF09946.4 EPS34916.1 - 0.027 14.2 0.7 0.027 14.2 0.5 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2178) Herpes_US9 PF06072.6 EPS34916.1 - 3.4 7.5 5.8 16 5.3 0.7 3.1 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Fungal_trans PF04082.13 EPS34917.1 - 7e-14 51.3 0.2 1.3e-13 50.4 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS34917.1 - 7e-06 25.8 11.6 1.3e-05 25.0 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAA_hydrolase PF01557.13 EPS34918.1 - 1.1e-46 159.0 0.0 1.5e-46 158.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 EPS34918.1 - 1.3e-15 57.3 0.0 3.6e-15 55.8 0.0 1.8 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal DUF4066 PF13278.1 EPS34919.1 - 5.8e-22 77.7 0.0 9.6e-22 77.0 0.0 1.3 1 1 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EPS34919.1 - 1.1e-07 31.4 0.0 1e-06 28.2 0.0 2.1 1 1 0 1 1 1 1 DJ-1/PfpI family DIT1_PvcA PF05141.7 EPS34920.1 - 2.7e-89 299.1 0.0 3.9e-89 298.6 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.11 EPS34920.1 - 2.3e-28 99.5 0.0 3.6e-28 98.9 0.0 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family HRM PF02793.17 EPS34921.1 - 0.08 12.9 0.3 0.23 11.4 0.2 1.7 1 0 0 1 1 1 0 Hormone receptor domain Tau95 PF09734.4 EPS34924.1 - 7.2e-72 242.3 0.0 9.8e-72 241.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit B56 PF01603.15 EPS34925.1 - 2.4e-173 576.4 7.9 2.9e-173 576.1 5.5 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) FAT PF02259.18 EPS34926.1 - 2.4e-72 243.8 9.3 5.5e-72 242.6 6.5 1.7 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 EPS34926.1 - 2.8e-30 105.5 0.1 1.7e-29 102.9 0.1 2.3 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EPS34926.1 - 9.4e-08 31.3 0.1 2.9e-07 29.7 0.1 1.9 1 0 0 1 1 1 1 FATC domain TPR_2 PF07719.12 EPS34926.1 - 0.3 11.1 4.6 1.3 9.0 0.3 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF572 PF04502.8 EPS34927.1 - 6.5e-71 239.1 11.4 7.6e-71 238.9 7.9 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Rota_VP2 PF05087.7 EPS34927.1 - 7.2 4.3 6.3 8.9 4.0 4.4 1.0 1 0 0 1 1 1 0 Rotavirus VP2 protein TPR_1 PF00515.23 EPS34928.1 - 3.1e-30 102.5 4.2 0.00037 19.9 0.0 10.2 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_11 PF13414.1 EPS34928.1 - 3.8e-29 100.1 13.5 7.6e-11 41.4 0.0 7.5 6 1 1 7 7 7 6 TPR repeat TPR_2 PF07719.12 EPS34928.1 - 8e-29 97.2 12.7 0.0029 17.3 0.0 10.2 10 0 0 10 10 10 7 Tetratricopeptide repeat Apc3 PF12895.2 EPS34928.1 - 1.8e-23 82.4 12.2 1.1e-18 67.1 1.3 5.4 5 0 0 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EPS34928.1 - 3.5e-20 71.7 24.6 4.2e-11 42.6 0.1 9.3 9 1 0 9 9 9 4 Tetratricopeptide repeat TPR_19 PF14559.1 EPS34928.1 - 3e-17 62.7 15.3 2.7e-06 27.6 0.1 7.5 6 2 3 9 9 9 6 Tetratricopeptide repeat TPR_14 PF13428.1 EPS34928.1 - 7.3e-17 60.3 20.0 0.23 12.1 0.3 10.0 8 2 2 10 10 9 4 Tetratricopeptide repeat TPR_16 PF13432.1 EPS34928.1 - 2.9e-15 56.4 24.6 2.5e-05 24.8 0.8 8.6 7 2 2 9 9 9 6 Tetratricopeptide repeat TPR_8 PF13181.1 EPS34928.1 - 3.5e-12 45.1 0.0 0.92 9.4 0.0 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 EPS34928.1 - 1.6e-08 34.4 10.9 0.99 10.0 0.0 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 EPS34928.1 - 2.3e-08 33.1 19.7 1.1 9.2 0.0 9.2 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_17 PF13431.1 EPS34928.1 - 2.8e-08 33.3 2.0 0.29 11.4 0.0 8.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_4 PF07721.9 EPS34928.1 - 5.4e-06 26.3 12.7 1.8 9.2 0.7 8.4 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_10 PF13374.1 EPS34928.1 - 1.6e-05 24.6 1.2 0.0049 16.7 0.1 8.6 11 0 0 11 11 9 2 Tetratricopeptide repeat DUF3856 PF12968.2 EPS34928.1 - 0.02 14.7 0.3 2.9 7.7 0.0 3.7 4 0 0 4 4 4 0 Domain of Unknown Function (DUF3856) TPR_9 PF13371.1 EPS34928.1 - 0.033 14.0 19.1 19 5.2 0.1 6.9 5 2 1 6 6 6 0 Tetratricopeptide repeat TPR_21 PF09976.4 EPS34928.1 - 0.051 13.5 6.1 5.7 6.8 0.0 5.1 5 1 0 5 5 5 0 Tetratricopeptide repeat Glyco_transf_90 PF05686.7 EPS34929.1 - 1.3e-26 93.2 0.2 1.7e-26 92.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 90 CVNH PF08881.5 EPS34930.1 - 1e-27 96.3 0.0 1.2e-27 96.1 0.0 1.0 1 0 0 1 1 1 1 CVNH domain NikR_C PF08753.6 EPS34930.1 - 0.14 12.0 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 NikR C terminal nickel binding domain MCM PF00493.18 EPS34931.1 - 1.2e-141 471.3 0.1 1.5e-141 471.0 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EPS34931.1 - 2.2e-19 70.1 0.3 7.6e-19 68.3 0.1 2.0 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EPS34931.1 - 3.9e-06 26.1 0.0 0.00089 18.4 0.0 2.3 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EPS34931.1 - 5.8e-05 22.8 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EPS34931.1 - 0.0007 19.2 0.0 0.0026 17.3 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 EPS34931.1 - 0.016 15.6 0.4 0.057 13.8 0.2 2.0 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EPS34931.1 - 0.046 13.1 0.0 1.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Vps54 PF07928.7 EPS34932.1 - 1.4e-48 164.4 1.0 5.6e-48 162.5 0.2 2.3 2 0 0 2 2 2 1 Vps54-like protein DUF2450 PF10475.4 EPS34932.1 - 7.2e-05 21.8 3.5 0.00016 20.6 1.9 1.9 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) DUF2451 PF10474.4 EPS34932.1 - 0.0083 15.9 0.1 0.025 14.3 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) LUC7 PF03194.10 EPS34932.1 - 0.014 14.9 2.9 0.023 14.2 0.9 2.2 2 0 0 2 2 2 0 LUC7 N_terminus COG2 PF06148.6 EPS34932.1 - 0.67 9.8 4.1 1.1 9.1 1.3 2.6 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Glycogen_syn PF05693.8 EPS34934.1 - 0 1122.4 0.0 0 1122.2 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_trans_4_4 PF13579.1 EPS34934.1 - 1.9e-06 28.1 0.1 4.1e-06 27.0 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.15 EPS34934.1 - 3.7e-05 23.2 0.0 0.0013 18.1 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 NMT1 PF09084.6 EPS34935.1 - 1.4e-74 250.3 0.0 2.5e-74 249.5 0.0 1.4 2 0 0 2 2 2 1 NMT1/THI5 like NMT1_2 PF13379.1 EPS34935.1 - 3.4e-07 29.9 0.4 0.073 12.4 0.0 3.2 2 1 0 3 3 3 3 NMT1-like family Phosphonate-bd PF12974.2 EPS34935.1 - 0.13 11.6 0.0 0.26 10.6 0.0 1.4 1 1 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Mannosyl_trans3 PF11051.3 EPS34936.1 - 1.1e-61 208.5 0.0 1.6e-61 208.0 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative polyprenyl_synt PF00348.12 EPS34937.1 - 1.3e-71 240.4 0.0 1.6e-71 240.2 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase DUF4457 PF14652.1 EPS34937.1 - 0.085 11.8 0.1 0.14 11.1 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4457) APC8 PF04049.8 EPS34938.1 - 4.8e-53 178.7 0.1 5.7e-52 175.2 0.0 2.4 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 EPS34938.1 - 6.5e-22 76.1 4.6 0.00063 19.2 0.0 7.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.1 EPS34938.1 - 6.1e-21 73.8 7.2 1.1e-06 28.1 0.0 5.9 4 1 1 5 5 5 4 TPR repeat TPR_2 PF07719.12 EPS34938.1 - 4.8e-17 60.4 13.5 0.066 13.1 0.0 8.9 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.1 EPS34938.1 - 6.2e-17 60.0 4.8 0.014 15.0 0.0 6.7 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 EPS34938.1 - 1.2e-15 57.6 18.0 0.00013 22.5 1.4 7.5 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 EPS34938.1 - 1.5e-13 50.0 15.5 0.02 15.4 0.0 8.9 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.1 EPS34938.1 - 1.2e-09 38.3 12.2 0.015 15.6 0.2 7.7 9 0 0 9 9 7 2 Tetratricopeptide repeat Apc3 PF12895.2 EPS34938.1 - 2.8e-09 36.9 13.4 0.34 11.0 0.2 6.3 6 1 0 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EPS34938.1 - 4.6e-08 32.8 24.5 0.11 12.4 0.6 6.9 6 1 2 8 8 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 EPS34938.1 - 3.6e-07 29.8 8.1 0.17 12.1 0.0 7.1 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 EPS34938.1 - 6.2e-06 25.9 4.4 0.0001 22.0 0.4 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EPS34938.1 - 1.2e-05 24.7 7.9 2 8.4 0.0 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EPS34938.1 - 9.1e-05 22.6 24.7 1.7 9.2 0.3 9.9 10 1 0 10 10 10 2 Tetratricopeptide repeat TPR_15 PF13429.1 EPS34938.1 - 0.0011 18.0 7.8 0.003 16.6 1.7 3.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 EPS34938.1 - 0.044 13.7 12.3 17 5.4 0.0 6.5 6 1 1 7 7 7 0 Tetratricopeptide repeat DNA_ligase_A_M PF01068.16 EPS34939.1 - 1.2e-23 83.5 0.0 2.1e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EPS34939.1 - 7.9e-14 51.8 0.0 2.6e-13 50.1 0.0 1.9 2 0 0 2 2 2 1 DNA ligase N terminus DUF3449 PF11931.3 EPS34940.1 - 4.2e-70 235.2 0.8 1.2e-69 233.7 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 EPS34940.1 - 1.9e-14 52.8 0.6 4.1e-14 51.8 0.4 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-C2H2_jaz PF12171.3 EPS34940.1 - 2.1e-09 37.2 0.5 1.6e-07 31.2 0.1 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EPS34940.1 - 4.5e-08 33.0 0.5 5e-06 26.5 0.1 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EPS34940.1 - 0.00052 20.1 3.0 0.15 12.4 0.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EPS34940.1 - 0.004 17.2 0.1 0.047 13.7 0.0 2.6 3 0 0 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EPS34940.1 - 0.15 12.4 3.4 3.2 8.3 0.2 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type DEAD PF00270.24 EPS34941.1 - 5e-39 133.4 0.5 1.1e-38 132.4 0.2 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EPS34941.1 - 1.5e-29 101.6 0.2 3.3e-29 100.5 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EPS34941.1 - 0.011 15.5 0.1 0.05 13.4 0.1 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EPS34941.1 - 0.019 14.6 0.2 0.053 13.2 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 EPS34941.1 - 0.03 13.9 0.4 0.07 12.7 0.3 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EPS34941.1 - 0.059 13.5 0.9 0.27 11.4 0.6 2.0 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.9 EPS34941.1 - 0.064 13.0 0.8 0.2 11.4 0.0 2.2 3 0 0 3 3 3 0 Flavivirus DEAD domain DUF1253 PF06862.7 EPS34941.1 - 0.069 11.5 0.0 0.63 8.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) Beta-lactamase PF00144.19 EPS34942.1 - 2.1e-27 96.0 0.0 3.1e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase WD40 PF00400.27 EPS34943.1 - 2.3e-30 103.3 21.3 3.4e-07 29.8 0.5 7.3 7 1 0 7 7 7 5 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EPS34943.1 - 2.2e-06 26.2 0.2 0.0047 15.2 0.1 2.4 2 1 0 2 2 2 2 Cytochrome D1 heme domain CLTH PF10607.4 EPS34943.1 - 2.8e-05 23.8 0.5 4.4e-05 23.1 0.3 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain PD40 PF07676.7 EPS34943.1 - 0.00012 21.5 0.1 3.6 7.3 0.0 4.5 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat eIF2A PF08662.6 EPS34943.1 - 0.00016 21.4 0.8 0.14 11.8 0.0 3.3 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EPS34943.1 - 0.0012 16.7 0.5 0.12 10.1 0.0 2.6 2 1 0 2 2 2 2 IKI3 family DUF1668 PF07893.8 EPS34943.1 - 0.0044 16.1 0.2 0.76 8.8 0.0 2.5 1 1 0 2 2 2 2 Protein of unknown function (DUF1668) YcgR PF07317.7 EPS34943.1 - 0.073 12.8 0.0 0.35 10.6 0.0 2.1 2 0 0 2 2 2 0 Flagellar regulator YcgR DUF2236 PF09995.4 EPS34944.1 - 1.4e-37 129.2 0.0 2.4e-37 128.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) HTH_psq PF05225.11 EPS34944.1 - 0.059 12.9 0.0 0.17 11.4 0.0 1.8 1 0 0 1 1 1 0 helix-turn-helix, Psq domain PEP_mutase PF13714.1 EPS34945.1 - 7.6e-63 211.9 1.3 8.5e-63 211.7 0.9 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase FAD_binding_3 PF01494.14 EPS34946.1 - 3.7e-21 75.5 0.0 7.6e-21 74.5 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EPS34946.1 - 2.6e-10 39.7 0.3 2.6e-05 23.2 0.0 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPS34946.1 - 4e-05 23.5 0.0 8.5e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EPS34946.1 - 0.00012 20.8 0.5 0.011 14.3 0.1 2.6 2 1 1 3 3 3 2 Tryptophan halogenase GIDA PF01134.17 EPS34946.1 - 0.00015 20.7 0.0 0.0003 19.7 0.0 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 EPS34946.1 - 0.00027 21.2 0.0 0.039 14.3 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EPS34946.1 - 0.0019 18.0 0.0 0.0047 16.8 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EPS34946.1 - 0.0033 16.3 0.0 0.012 14.5 0.0 1.9 3 0 0 3 3 3 1 FAD binding domain Lycopene_cycl PF05834.7 EPS34946.1 - 0.0041 16.0 0.2 0.0085 15.0 0.2 1.7 1 1 0 1 1 1 1 Lycopene cyclase protein SE PF08491.5 EPS34946.1 - 0.018 13.9 0.0 3.3 6.4 0.0 2.2 2 0 0 2 2 2 0 Squalene epoxidase NAD_binding_9 PF13454.1 EPS34946.1 - 0.023 14.4 0.1 0.045 13.5 0.1 1.7 1 1 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EPS34946.1 - 0.06 13.3 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EPS34946.1 - 0.086 11.2 0.0 0.14 10.6 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 EPS34946.1 - 0.12 11.3 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family MFS_1 PF07690.11 EPS34947.1 - 6.9e-57 192.7 36.7 9.8e-44 149.4 8.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EPS34947.1 - 2.1e-08 32.9 24.3 7.6e-05 21.2 0.3 3.5 3 1 1 4 4 4 2 MFS/sugar transport protein LacY_symp PF01306.14 EPS34947.1 - 0.05 12.1 18.2 0.011 14.3 0.9 3.3 3 1 0 3 3 3 0 LacY proton/sugar symporter OATP PF03137.15 EPS34947.1 - 0.34 8.9 8.0 0.07 11.1 0.2 2.9 3 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Trypsin_2 PF13365.1 EPS34948.1 - 0.0002 21.3 0.0 0.00077 19.4 0.0 1.9 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S7 PF00949.16 EPS34948.1 - 0.01 15.2 0.0 0.023 14.0 0.0 1.6 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease KRTDAP PF15200.1 EPS34948.1 - 0.14 11.9 0.1 0.3 10.8 0.1 1.5 1 0 0 1 1 1 0 Keratinocyte differentiation-associated ATP-synt_ab PF00006.20 EPS34949.1 - 6.1e-113 375.6 0.0 8.7e-113 375.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.18 EPS34949.1 - 3.8e-16 59.0 0.6 7.8e-16 58.0 0.4 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_ab_C PF00306.22 EPS34949.1 - 8e-16 58.5 0.6 1.3e-15 57.8 0.4 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain HSBP1 PF06825.7 EPS34949.1 - 0.057 13.0 0.1 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 Dynamin_M PF01031.15 EPS34950.1 - 1.3e-105 352.4 0.9 1.6e-105 352.1 0.1 1.5 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 EPS34950.1 - 1.4e-56 190.9 0.1 2.7e-56 189.9 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EPS34950.1 - 5.2e-30 103.1 4.2 5.2e-30 103.1 2.9 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EPS34950.1 - 0.00025 20.9 0.2 0.0022 17.9 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EPS34950.1 - 0.0044 17.4 0.0 0.028 14.8 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein DUF2226 PF09987.4 EPS34950.1 - 0.016 14.3 0.4 0.83 8.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2226) CN_hydrolase PF00795.17 EPS34952.1 - 2.6e-30 105.1 0.0 3.3e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Glyco_hydro_16 PF00722.16 EPS34953.1 - 6.6e-10 38.5 0.1 1e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 PH PF00169.24 EPS34954.1 - 0.0045 17.1 0.7 0.013 15.6 0.5 1.7 1 0 0 1 1 1 1 PH domain RmlD_sub_bind PF04321.12 EPS34955.1 - 1.5e-56 191.3 0.0 1.9e-56 191.0 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EPS34955.1 - 8.2e-24 84.3 0.0 1e-23 83.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EPS34955.1 - 1.9e-14 53.2 1.3 1.5e-12 47.0 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 EPS34955.1 - 1.6e-11 43.4 0.0 8.6e-11 41.0 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EPS34955.1 - 2.9e-11 42.7 0.3 2e-08 33.4 0.0 3.0 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EPS34955.1 - 1.2e-08 35.2 0.2 1.6e-08 34.7 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EPS34955.1 - 1.2e-06 28.5 0.3 5.7e-05 23.0 0.2 2.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EPS34955.1 - 7.2e-05 22.5 0.3 0.081 12.5 0.0 2.9 3 0 0 3 3 3 2 KR domain NmrA PF05368.8 EPS34955.1 - 0.15 11.2 0.6 7.6 5.7 0.2 2.9 2 1 0 2 2 2 0 NmrA-like family FAD-oxidase_C PF02913.14 EPS34956.1 - 1.6e-60 204.4 0.0 2.2e-60 204.0 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EPS34956.1 - 5.9e-38 129.4 0.4 1.3e-37 128.3 0.2 1.6 2 0 0 2 2 2 1 FAD binding domain Pkinase PF00069.20 EPS34957.1 - 1.6e-70 237.2 0.0 2.1e-70 236.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EPS34957.1 - 7.8e-48 162.7 0.0 1.1e-47 162.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EPS34957.1 - 3.4e-05 22.9 0.0 0.00032 19.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like DUF4048 PF13257.1 EPS34958.1 - 2.2e-79 266.7 20.1 2.2e-79 266.7 13.9 3.0 4 0 0 4 4 4 1 Domain of unknown function (DUF4048) Bap31 PF05529.7 EPS34958.1 - 0.37 10.2 1.0 0.7 9.3 0.7 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Tim17 PF02466.14 EPS34959.1 - 1.7e-51 173.5 5.7 2.2e-51 173.1 4.0 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_Omp PF13488.1 EPS34959.1 - 0.7 9.5 14.7 0.06 12.9 2.9 2.7 3 0 0 3 3 3 0 Glycine zipper Cnd3 PF12719.2 EPS34960.1 - 8.4e-95 317.1 0.0 1.2e-93 313.3 0.0 2.5 2 1 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 EPS34960.1 - 1.8e-10 40.9 1.3 7.5e-06 26.1 0.1 4.2 3 0 0 3 3 3 2 HEAT repeats Adaptin_N PF01602.15 EPS34960.1 - 2.8e-05 22.6 0.3 0.045 12.0 0.1 2.5 3 0 0 3 3 3 2 Adaptin N terminal region HEAT_EZ PF13513.1 EPS34960.1 - 3.2e-05 24.2 3.9 0.54 10.8 0.2 5.3 3 1 2 5 5 5 3 HEAT-like repeat HEAT PF02985.17 EPS34960.1 - 0.0015 18.4 3.1 2.9 8.2 0.0 5.6 5 0 0 5 5 5 1 HEAT repeat Ric8 PF10165.4 EPS34960.1 - 0.0029 16.5 0.6 0.0056 15.5 0.1 1.7 2 0 0 2 2 2 1 Guanine nucleotide exchange factor synembryn Cnd1 PF12717.2 EPS34960.1 - 0.016 15.0 0.0 7.8 6.3 0.0 3.6 2 2 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 DUF1546 PF07571.8 EPS34960.1 - 0.033 14.2 0.0 0.15 12.1 0.0 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1546) zf-RanBP PF00641.13 EPS34962.1 - 1e-20 72.5 9.1 6.4e-11 41.1 1.1 2.4 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 EPS34962.1 - 2e-08 33.7 0.0 5.9e-08 32.2 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EPS34962.1 - 1.3e-06 28.2 0.0 8e-06 25.7 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.19 EPS34962.1 - 9.1e-06 26.0 0.0 1.4e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DZR PF12773.2 EPS34962.1 - 0.51 10.2 8.3 0.81 9.5 0.8 2.5 2 0 0 2 2 2 0 Double zinc ribbon Proteasome PF00227.21 EPS34964.1 - 1.4e-55 187.5 0.1 2e-55 187.0 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EPS34964.1 - 6.3e-14 50.9 0.1 6.3e-14 50.9 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Terminase_5 PF06056.7 EPS34964.1 - 0.067 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) zf-CHY PF05495.7 EPS34965.1 - 1.8e-14 53.6 21.8 2.3e-14 53.2 15.1 1.1 1 0 0 1 1 1 1 CHY zinc finger C1_4 PF07975.7 EPS34965.1 - 0.015 15.2 14.0 0.13 12.2 5.8 2.4 1 1 1 2 2 2 0 TFIIH C1-like domain Helicase_IV_N PF12462.3 EPS34965.1 - 0.032 13.8 0.3 0.039 13.5 0.2 1.1 1 0 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal Zn_Tnp_IS1595 PF12760.2 EPS34965.1 - 0.13 12.1 11.3 2.9 7.7 5.6 2.6 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Tmemb_55A PF09788.4 EPS34965.1 - 0.13 11.3 8.3 0.15 11.1 5.8 1.1 1 0 0 1 1 1 0 Transmembrane protein 55A DUF3797 PF12677.2 EPS34965.1 - 0.62 9.7 0.0 0.62 9.7 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3797) zf-RING_3 PF14369.1 EPS34965.1 - 0.82 9.7 12.1 0.78 9.7 5.0 2.7 1 1 1 2 2 2 0 zinc-finger HypA PF01155.14 EPS34965.1 - 2.1 8.0 12.7 8.6 6.0 8.8 1.9 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Exo_endo_phos PF03372.18 EPS34966.1 - 8.1e-26 91.4 0.1 1.4e-25 90.7 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PQQ_2 PF13360.1 EPS34966.1 - 0.003 17.0 0.4 0.0064 15.9 0.2 1.6 1 0 0 1 1 1 1 PQQ-like domain DAO PF01266.19 EPS34968.1 - 4.8e-33 114.5 0.1 8.9e-33 113.6 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EPS34968.1 - 4.7e-05 23.3 0.6 0.00027 20.9 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EPS34968.1 - 6.3e-05 22.9 0.0 0.00019 21.4 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EPS34968.1 - 0.00071 19.3 0.4 0.01 15.6 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EPS34968.1 - 0.0045 17.0 0.0 2 8.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPS34968.1 - 0.013 14.5 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 EPS34968.1 - 0.11 12.9 0.1 0.66 10.4 0.0 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase YqfQ PF14181.1 EPS34969.1 - 0.00054 20.0 4.8 0.00061 19.8 3.4 1.1 1 0 0 1 1 1 1 YqfQ-like protein RNA_polI_A34 PF08208.6 EPS34969.1 - 0.1 12.2 7.7 0.091 12.4 5.3 1.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RXT2_N PF08595.6 EPS34969.1 - 0.12 12.1 6.4 0.13 12.0 4.4 1.2 1 0 0 1 1 1 0 RXT2-like, N-terminal RNA_pol_Rpc4 PF05132.9 EPS34969.1 - 0.15 12.0 4.5 0.13 12.2 3.1 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 TRAP_alpha PF03896.11 EPS34969.1 - 0.15 10.9 9.3 0.15 11.0 6.4 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit FAM176 PF14851.1 EPS34969.1 - 0.16 11.6 6.9 0.18 11.4 4.8 1.2 1 0 0 1 1 1 0 FAM176 family Sigma70_ner PF04546.8 EPS34969.1 - 0.17 11.4 13.8 0.17 11.4 9.6 1.0 1 0 0 1 1 1 0 Sigma-70, non-essential region D123 PF07065.9 EPS34969.1 - 0.23 10.5 3.6 0.24 10.4 2.5 1.0 1 0 0 1 1 1 0 D123 PAXIP1_C PF15364.1 EPS34969.1 - 0.33 10.8 11.1 0.39 10.6 7.7 1.1 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein DUF4366 PF14283.1 EPS34969.1 - 0.37 10.1 8.4 0.43 9.9 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Tim54 PF11711.3 EPS34969.1 - 0.49 8.9 5.7 0.44 9.1 3.9 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SHR3_chaperone PF08229.6 EPS34969.1 - 0.57 9.0 2.2 0.54 9.1 1.5 1.1 1 0 0 1 1 1 0 ER membrane protein SH3 CENP-B_dimeris PF09026.5 EPS34969.1 - 0.58 10.4 18.3 0.79 9.9 12.7 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ycf1 PF05758.7 EPS34969.1 - 0.89 7.1 6.8 0.79 7.3 4.7 1.0 1 0 0 1 1 1 0 Ycf1 Usp PF00582.21 EPS34969.1 - 0.92 9.6 5.5 1.1 9.4 3.8 1.2 1 0 0 1 1 1 0 Universal stress protein family Nucleoplasmin PF03066.10 EPS34969.1 - 0.97 8.9 23.0 1.1 8.7 15.9 1.1 1 0 0 1 1 1 0 Nucleoplasmin SspB PF04386.8 EPS34969.1 - 1.1 8.8 7.9 1.2 8.7 5.5 1.1 1 0 0 1 1 1 0 Stringent starvation protein B Prog_receptor PF02161.10 EPS34969.1 - 1.2 7.8 7.9 1.1 8.0 5.5 1.0 1 0 0 1 1 1 0 Progesterone receptor TFIIF_alpha PF05793.7 EPS34969.1 - 1.6 6.9 18.0 1.4 7.1 12.5 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) ANAPC15 PF15243.1 EPS34969.1 - 1.7 8.7 20.5 2 8.5 14.2 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 CDC45 PF02724.9 EPS34969.1 - 1.9 6.4 11.0 1.9 6.4 7.6 1.0 1 0 0 1 1 1 0 CDC45-like protein OAD_gamma PF04277.8 EPS34969.1 - 2.9 8.3 5.5 3.6 8.0 3.8 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Adeno_terminal PF02459.10 EPS34969.1 - 3.5 5.6 12.3 3.6 5.6 8.6 1.0 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Sporozoite_P67 PF05642.6 EPS34969.1 - 3.7 5.2 7.5 3.4 5.4 5.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Phage_Gp23 PF10669.4 EPS34969.1 - 4.7 7.3 5.6 5.3 7.1 3.9 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) HSP90 PF00183.13 EPS34969.1 - 5.7 5.2 17.4 5.9 5.1 12.1 1.0 1 0 0 1 1 1 0 Hsp90 protein RAB3GAP2_C PF14656.1 EPS34969.1 - 6 4.8 6.5 5.7 4.9 4.5 1.0 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus Daxx PF03344.10 EPS34969.1 - 8.3 4.7 23.5 8.7 4.6 16.3 1.0 1 0 0 1 1 1 0 Daxx Family Radial_spoke PF04712.7 EPS34969.1 - 9.2 4.8 24.5 9.4 4.8 17.0 1.0 1 0 0 1 1 1 0 Radial spokehead-like protein DUF3431 PF11913.3 EPS34971.1 - 6e-81 271.1 0.0 7.4e-81 270.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) F-box-like PF12937.2 EPS34972.1 - 1.7e-07 30.8 0.2 3.4e-07 29.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like GFA PF04828.9 EPS34973.1 - 1.1e-09 38.1 4.2 2.2e-09 37.1 2.9 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme NPP1 PF05630.6 EPS34974.1 - 3.5e-06 26.8 5.7 4.4e-06 26.5 0.4 2.7 2 1 0 3 3 3 1 Necrosis inducing protein (NPP1) DAO PF01266.19 EPS34975.1 - 1.5e-60 204.9 0.0 1.8e-60 204.7 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EPS34975.1 - 6e-05 23.2 0.0 0.06 13.3 0.0 2.5 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EPS34975.1 - 0.00029 20.7 1.4 0.00049 20.0 0.2 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EPS34975.1 - 0.0003 19.7 0.1 0.033 13.0 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.1 EPS34975.1 - 0.0012 18.6 0.1 0.085 12.6 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EPS34975.1 - 0.013 14.4 0.1 0.019 13.8 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein CNTF PF01110.12 EPS34975.1 - 0.028 13.7 0.0 0.054 12.7 0.0 1.4 1 0 0 1 1 1 0 Ciliary neurotrophic factor Pyr_redox_2 PF07992.9 EPS34975.1 - 0.036 13.9 0.0 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EPS34975.1 - 0.037 13.1 0.0 0.077 12.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EPS34975.1 - 0.1 11.0 0.1 4.5 5.6 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein K_oxygenase PF13434.1 EPS34975.1 - 0.14 11.0 0.0 4 6.2 0.0 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Chromate_transp PF02417.10 EPS34976.1 - 6.2e-53 178.8 30.0 3.4e-27 95.1 9.4 2.1 2 0 0 2 2 2 2 Chromate transporter UPF0047 PF01894.12 EPS34977.1 - 2.7e-40 136.8 0.0 3e-40 136.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 zf-CHCC PF10276.4 EPS34978.1 - 4.8e-17 61.5 0.8 7.5e-17 60.8 0.5 1.3 1 0 0 1 1 1 1 Zinc-finger domain Spt5_N PF11942.3 EPS34979.1 - 0.0025 18.3 5.8 0.0025 18.3 4.1 2.0 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal CDC45 PF02724.9 EPS34979.1 - 0.013 13.5 4.8 0.017 13.1 3.3 1.2 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 EPS34979.1 - 0.083 12.3 1.7 0.11 11.9 1.2 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF4611 PF15387.1 EPS34979.1 - 0.26 11.4 6.6 0.15 12.2 2.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) YqfQ PF14181.1 EPS34979.1 - 4.6 7.2 8.0 0.36 10.8 2.2 1.7 2 0 0 2 2 2 0 YqfQ-like protein Sigma70_ner PF04546.8 EPS34979.1 - 5.4 6.5 12.1 0.16 11.5 3.9 1.6 2 0 0 2 2 2 0 Sigma-70, non-essential region CoaE PF01121.15 EPS34980.1 - 1.7e-41 141.5 0.0 2.6e-41 140.9 0.0 1.2 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 EPS34980.1 - 0.0014 19.4 0.1 0.0026 18.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EPS34980.1 - 0.0091 16.3 0.3 0.24 11.7 0.1 2.4 2 1 0 2 2 2 1 AAA domain 2TM PF13239.1 EPS34980.1 - 0.012 15.6 0.3 0.025 14.6 0.2 1.5 1 0 0 1 1 1 0 2TM domain DUF3431 PF11913.3 EPS34981.1 - 7.2e-90 300.3 0.2 1.1e-89 299.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3431) Lipase_3 PF01764.20 EPS34982.1 - 8.6e-39 132.3 0.0 1.2e-38 131.8 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.11 EPS34982.1 - 2.4e-08 33.6 0.0 5.6e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Lipase 3 N-terminal region Abhydrolase_8 PF06259.7 EPS34982.1 - 0.0012 18.4 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase Abhydrolase_5 PF12695.2 EPS34982.1 - 0.0058 16.3 0.1 0.015 15.0 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF2974 PF11187.3 EPS34982.1 - 0.019 14.3 0.4 0.38 10.0 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.2 EPS34982.1 - 0.085 12.7 0.3 0.1 12.4 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase family GHMP_kinases_C PF08544.8 EPS34982.1 - 0.13 12.5 0.1 0.24 11.6 0.1 1.4 1 0 0 1 1 1 0 GHMP kinases C terminal NUDIX_2 PF13869.1 EPS34983.1 - 5.3e-82 273.7 0.0 6.3e-82 273.4 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Peptidase_M16 PF00675.15 EPS34984.1 - 1.4e-29 102.7 5.8 1.6e-20 73.3 0.2 3.6 3 1 1 4 4 4 2 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EPS34984.1 - 3.3e-29 101.8 0.0 7.1e-19 68.1 0.0 3.3 3 0 0 3 3 3 2 Peptidase M16 inactive domain Bys1 PF04681.7 EPS34985.1 - 3e-10 40.0 0.3 3.6e-10 39.7 0.2 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein Hist_deacetyl PF00850.14 EPS34986.1 - 1.2e-94 317.1 0.1 2.5e-94 316.0 0.1 1.5 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 EPS34986.1 - 4.1e-52 176.1 0.9 7.4e-52 175.3 0.3 1.7 2 0 0 2 2 2 1 Arb2 domain Gp_dh_C PF02800.15 EPS34987.1 - 8.3e-76 252.7 0.2 1.5e-75 251.9 0.1 1.5 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EPS34987.1 - 3.6e-59 199.0 0.2 7.9e-59 197.9 0.1 1.6 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 EPS34987.1 - 0.039 13.8 0.2 0.27 11.1 0.0 2.4 3 0 0 3 3 3 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 EPS34987.1 - 0.12 11.4 0.1 0.36 9.9 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pho88 PF10032.4 EPS34988.1 - 6.4e-79 263.6 0.4 7.2e-79 263.4 0.3 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF2576 PF10845.3 EPS34988.1 - 0.15 11.2 0.0 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) Histone PF00125.19 EPS34989.1 - 4.3e-22 78.0 0.0 5.5e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EPS34989.1 - 5e-05 23.2 0.0 6.9e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone R3H PF01424.17 EPS34991.1 - 5.2e-12 45.2 0.0 1.1e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 R3H domain RRM_6 PF14259.1 EPS34991.1 - 1.2e-06 28.3 0.0 2.1e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EPS34991.1 - 6e-06 25.7 0.1 1.4e-05 24.6 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EPS34991.1 - 0.0079 16.0 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUZ-C PF12901.2 EPS34991.1 - 0.048 13.2 5.6 0.032 13.8 1.4 2.8 2 0 0 2 2 2 0 SUZ-C motif Sporozoite_P67 PF05642.6 EPS34994.1 - 0.17 9.7 4.2 0.22 9.3 2.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ATG27 PF09451.5 EPS34994.1 - 3.5 6.7 8.7 0.8 8.8 3.9 1.4 2 0 0 2 2 2 0 Autophagy-related protein 27 Aldo_ket_red PF00248.16 EPS34995.1 - 2.6e-20 72.4 0.0 4e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family SANTA PF09133.5 EPS34995.1 - 0.05 13.5 0.0 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 SANTA (SANT Associated) XkdW PF09636.5 EPS34995.1 - 0.051 13.4 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 XkdW protein ATP_bind_4 PF01902.12 EPS34995.1 - 0.08 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 ATP-binding region HSF_DNA-bind PF00447.12 EPS34996.1 - 1.4e-28 99.0 0.1 2.6e-28 98.2 0.1 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Filament PF00038.16 EPS34996.1 - 0.069 12.6 1.8 0.73 9.2 0.6 2.2 2 0 0 2 2 2 0 Intermediate filament protein Ets PF00178.17 EPS34996.1 - 0.072 13.2 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Ets-domain Syntaxin PF00804.20 EPS34996.1 - 0.53 10.4 4.9 0.82 9.8 0.3 2.6 2 0 0 2 2 2 0 Syntaxin Tmemb_cc2 PF10267.4 EPS34996.1 - 1.2 7.6 6.3 0.07 11.7 0.2 1.9 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Pro_isomerase PF00160.16 EPS34997.1 - 1.8e-39 135.4 0.0 3.6e-39 134.4 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4604 PF15377.1 EPS34997.1 - 0.0012 19.0 0.4 0.0012 19.0 0.3 3.7 3 1 0 3 3 3 1 Domain of unknown function (DUF4604) Clr5 PF14420.1 EPS34998.1 - 2.4e-06 27.3 0.1 5.9e-06 26.0 0.0 1.6 2 0 0 2 2 2 1 Clr5 domain HTH_Tnp_Tc3_2 PF01498.13 EPS34998.1 - 6.1e-05 22.9 0.9 0.006 16.6 0.2 2.2 2 0 0 2 2 2 1 Transposase HTH_12 PF08461.5 EPS34998.1 - 0.00039 20.0 2.1 0.057 13.1 0.1 2.2 2 0 0 2 2 2 2 Ribonuclease R winged-helix domain HTH_32 PF13565.1 EPS34998.1 - 0.0034 18.1 2.2 0.15 12.8 0.4 2.2 1 1 1 2 2 2 1 Homeodomain-like domain Sigma54_DBD PF04552.8 EPS34998.1 - 0.0091 15.5 0.6 0.018 14.5 0.4 1.5 1 1 0 1 1 1 1 Sigma-54, DNA binding domain HTH_21 PF13276.1 EPS34998.1 - 0.022 14.7 2.5 0.74 9.8 0.1 2.6 2 1 0 2 2 2 0 HTH-like domain His_Phos_2 PF00328.17 EPS34999.1 - 2e-12 47.1 0.1 1.8e-11 44.0 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PDGLE PF13190.1 EPS34999.1 - 0.05 13.2 0.3 0.3 10.8 0.1 2.2 2 0 0 2 2 2 0 PDGLE domain TcpQ PF10671.4 EPS34999.1 - 0.065 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Toxin co-regulated pilus biosynthesis protein Q AAA PF00004.24 EPS35000.1 - 3.2e-16 59.7 0.0 5.8e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 EPS35000.1 - 4.3e-15 55.4 0.0 1.1e-14 54.1 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EPS35000.1 - 5.9e-14 52.0 0.1 1.7e-13 50.5 0.0 1.8 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EPS35000.1 - 4e-10 38.9 0.1 1.1e-07 30.9 0.0 2.4 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EPS35000.1 - 7.4e-08 32.6 0.2 2.3e-06 27.7 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EPS35000.1 - 1.6e-06 27.9 0.4 0.00014 21.5 0.0 2.4 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 EPS35000.1 - 1.9e-06 28.0 0.4 0.00031 20.7 0.0 3.2 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 EPS35000.1 - 2.3e-06 26.8 0.2 3.8e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EPS35000.1 - 2.5e-06 27.1 0.0 6.1e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EPS35000.1 - 8.4e-06 25.4 0.0 1.6e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.8 EPS35000.1 - 2.1e-05 24.1 0.0 3.6e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit TIP49 PF06068.8 EPS35000.1 - 3.8e-05 22.6 0.0 0.19 10.3 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_14 PF13173.1 EPS35000.1 - 4.3e-05 23.4 0.0 0.00011 22.0 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 EPS35000.1 - 4.7e-05 23.1 0.5 0.00023 20.9 0.1 2.4 2 1 1 3 3 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 EPS35000.1 - 6.8e-05 21.9 0.0 0.00012 21.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_3 PF07726.6 EPS35000.1 - 0.00013 21.6 0.1 0.0026 17.3 0.1 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 EPS35000.1 - 0.00038 20.1 0.0 0.00072 19.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EPS35000.1 - 0.00097 18.6 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain DUF2075 PF09848.4 EPS35000.1 - 0.0011 17.9 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 EPS35000.1 - 0.0014 18.1 0.1 0.065 12.7 0.0 2.4 1 1 1 2 2 2 1 DEAD/DEAH box helicase PhoH PF02562.11 EPS35000.1 - 0.0017 17.5 0.0 0.48 9.6 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_25 PF13481.1 EPS35000.1 - 0.004 16.5 0.4 0.019 14.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EPS35000.1 - 0.0068 15.8 0.0 0.39 10.1 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_28 PF13521.1 EPS35000.1 - 0.009 15.9 0.1 0.018 15.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EPS35000.1 - 0.0096 15.6 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase RNA_helicase PF00910.17 EPS35000.1 - 0.011 15.8 0.0 0.027 14.6 0.0 1.7 1 1 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.12 EPS35000.1 - 0.012 14.9 0.0 0.24 10.7 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein ResIII PF04851.10 EPS35000.1 - 0.014 15.2 0.0 0.11 12.2 0.0 2.0 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EPS35000.1 - 0.016 14.0 0.0 0.67 8.6 0.0 2.1 2 0 0 2 2 2 0 SNF2 family N-terminal domain AAA_10 PF12846.2 EPS35000.1 - 0.017 14.5 0.1 0.16 11.3 0.1 2.3 1 1 0 1 1 1 0 AAA-like domain AAA_18 PF13238.1 EPS35000.1 - 0.017 15.4 0.0 0.036 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EPS35000.1 - 0.017 14.2 0.2 0.12 11.5 0.1 2.4 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EPS35000.1 - 0.024 15.4 0.0 0.085 13.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EPS35000.1 - 0.07 13.4 0.0 0.13 12.5 0.0 1.5 1 1 0 1 1 1 0 ABC transporter SRP54 PF00448.17 EPS35000.1 - 0.073 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain P21-Arc PF04062.9 EPS35001.1 - 6.2e-79 263.8 0.0 6.9e-79 263.6 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Gcd10p PF04189.8 EPS35002.1 - 2.3e-102 342.1 0.0 3.5e-102 341.5 0.0 1.3 1 0 0 1 1 1 1 Gcd10p family DUF544 PF04424.8 EPS35003.1 - 4.7e-12 45.7 0.0 8e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF544) Cellulase PF00150.13 EPS35004.1 - 3.9e-37 127.9 0.5 7.2e-37 127.1 0.3 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_X2 PF03442.9 EPS35004.1 - 4e-25 87.4 2.5 4e-25 87.4 1.8 4.1 5 0 0 5 5 5 1 Carbohydrate binding domain X2 CBM_1 PF00734.13 EPS35004.1 - 1.2e-10 40.8 16.4 1.2e-10 40.8 11.3 1.9 2 0 0 2 2 2 1 Fungal cellulose binding domain DUF221 PF02714.10 EPS35005.1 - 2.8e-107 358.3 20.2 2.8e-107 358.3 14.0 1.7 3 0 0 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EPS35005.1 - 4.5e-40 136.7 1.8 4.5e-40 136.7 1.3 2.6 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EPS35005.1 - 4.2e-26 90.6 0.1 8.2e-26 89.7 0.1 1.4 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 EPS35005.1 - 6.5e-19 68.2 1.0 9.3e-19 67.7 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4463) Abhydrolase_6 PF12697.2 EPS35006.1 - 1.7e-17 64.0 0.1 2.6e-17 63.4 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EPS35006.1 - 1.7e-10 40.8 0.1 2.2e-09 37.2 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EPS35006.1 - 1.1e-05 25.2 0.0 8.2e-05 22.3 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EPS35006.1 - 0.015 14.6 0.0 0.12 11.5 0.0 2.4 3 0 0 3 3 3 0 Dienelactone hydrolase family BAAT_C PF08840.6 EPS35006.1 - 0.017 14.8 0.0 2.4 7.7 0.0 2.3 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.15 EPS35006.1 - 0.018 14.4 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.11 EPS35006.1 - 0.082 12.3 0.0 0.29 10.5 0.0 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PIG-P PF08510.7 EPS35007.1 - 2.7e-45 153.0 0.4 2.7e-45 153.0 0.3 1.8 2 0 0 2 2 2 1 PIG-P XPA_C PF05181.7 EPS35008.1 - 5e-29 99.6 3.0 1.2e-28 98.4 2.1 1.7 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.13 EPS35008.1 - 0.021 14.4 4.6 0.021 14.4 3.2 1.9 2 0 0 2 2 2 0 XPA protein N-terminal DZR PF12773.2 EPS35008.1 - 0.43 10.4 3.6 2 8.2 1.1 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-AD PF07776.10 EPS35008.1 - 0.5 10.4 4.7 3.7 7.6 3.2 2.3 1 1 0 1 1 1 0 Zinc-finger associated domain (zf-AD) YhfH PF14149.1 EPS35008.1 - 1.9 8.3 9.9 0.32 10.8 0.3 2.6 2 0 0 2 2 2 0 YhfH-like protein ArfGap PF01412.13 EPS35008.1 - 2.9 7.6 7.8 0.69 9.7 0.9 2.7 3 0 0 3 3 3 0 Putative GTPase activating protein for Arf DNA_RNApol_7kD PF03604.8 EPS35008.1 - 6.4 6.3 9.7 5.9 6.4 2.8 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Striatin PF08232.7 EPS35010.1 - 2.5e-43 147.6 9.3 2.5e-43 147.6 6.5 3.1 3 0 0 3 3 3 1 Striatin family WD40 PF00400.27 EPS35010.1 - 5.3e-31 105.3 16.4 1.4e-06 27.9 0.2 6.8 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EPS35010.1 - 0.019 14.7 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Blt1 PF12754.2 EPS35011.1 - 7.1e-64 216.3 0.3 2.3e-61 208.1 0.2 2.0 1 1 0 1 1 1 1 Cell-cycle control medial ring component DUF2407 PF10302.4 EPS35011.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Nol1_Nop2_Fmu PF01189.12 EPS35012.1 - 3.1e-93 312.2 0.0 1.3e-92 310.1 0.0 2.1 3 0 0 3 3 3 1 NOL1/NOP2/sun family FtsJ PF01728.14 EPS35012.1 - 0.00089 19.2 0.0 0.0018 18.2 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.14 EPS35012.1 - 0.038 13.5 0.0 0.074 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 EPS35012.1 - 0.089 12.8 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MORN PF02493.15 EPS35013.1 - 9.6e-16 56.4 21.4 0.0003 20.3 0.2 4.6 4 0 0 4 4 4 4 MORN repeat UCH PF00443.24 EPS35013.1 - 2.8e-12 46.3 0.0 4.4e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-C3HC4_3 PF13920.1 EPS35013.1 - 5.2e-11 42.0 15.0 8.3e-11 41.3 10.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) USP7_ICP0_bdg PF12436.3 EPS35013.1 - 2e-07 30.4 0.0 4.2e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 MATH PF00917.21 EPS35013.1 - 4.5e-05 23.6 0.0 0.31 11.2 0.0 2.5 2 0 0 2 2 2 2 MATH domain zf-C3HC4_2 PF13923.1 EPS35013.1 - 0.00079 19.4 14.5 0.002 18.0 10.0 1.7 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EPS35013.1 - 1.9 8.2 16.8 3.7 7.3 11.6 1.4 1 0 0 1 1 1 0 zinc-RING finger domain DS PF01916.12 EPS35014.1 - 5.1e-139 462.4 0.0 6e-139 462.2 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase CmcH_NodU PF02543.10 EPS35014.1 - 0.04 13.0 0.1 0.068 12.2 0.1 1.3 1 0 0 1 1 1 0 Carbamoyltransferase Myb_DNA-binding PF00249.26 EPS35016.1 - 1.4e-12 47.4 0.0 1.7e-07 31.1 0.0 3.3 3 0 0 3 3 3 2 Myb-like DNA-binding domain BTV_NS2 PF04514.7 EPS35016.1 - 0.078 11.8 6.3 0.15 10.9 4.4 1.4 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Ycf1 PF05758.7 EPS35016.1 - 5.3 4.6 3.5 7.3 4.1 2.4 1.1 1 0 0 1 1 1 0 Ycf1 Cation_efflux PF01545.16 EPS35017.1 - 7.8e-33 113.7 8.2 1e-32 113.3 5.7 1.1 1 0 0 1 1 1 1 Cation efflux family DUF4131 PF13567.1 EPS35017.1 - 0.011 15.2 2.6 0.015 14.7 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) p450 PF00067.17 EPS35019.1 - 1.5e-67 228.1 0.0 1.7e-67 227.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 EPS35020.1 - 8e-16 57.6 0.1 1.7e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EPS35020.1 - 4e-09 36.2 12.4 7.2e-09 35.4 8.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1524 PF07510.6 EPS35021.1 - 8.7e-15 54.8 0.0 1.2e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) Transp_cyt_pur PF02133.10 EPS35022.1 - 3e-46 157.8 34.2 3.4e-46 157.6 23.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF1689 PF07954.6 EPS35022.1 - 0.027 14.3 0.4 1 9.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1689) ArabFuran-catal PF09206.6 EPS35023.1 - 5.7e-167 554.5 19.2 9.4e-167 553.8 13.3 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.8 EPS35023.1 - 3.4e-62 208.3 2.5 5.4e-62 207.7 1.7 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) HATPase_c PF02518.21 EPS35025.1 - 1e-19 70.2 0.0 2e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EPS35025.1 - 5e-17 61.9 0.0 1.2e-16 60.7 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EPS35025.1 - 1e-13 51.0 0.2 9.2e-13 47.9 0.0 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain FAD_binding_4 PF01565.18 EPS35026.1 - 3.3e-33 114.0 7.6 5.5e-33 113.3 5.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EPS35026.1 - 1.2e-10 41.1 0.1 2.8e-10 39.9 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like FAD-oxidase_C PF02913.14 EPS35026.1 - 0.016 14.4 0.1 1.8 7.7 0.0 2.7 3 0 0 3 3 3 0 FAD linked oxidases, C-terminal domain Aa_trans PF01490.13 EPS35027.1 - 2.7e-40 138.1 35.1 3.4e-40 137.7 24.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CAAD PF14159.1 EPS35027.1 - 2.5 7.7 20.8 0.15 11.7 1.4 4.7 4 1 1 5 5 5 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Sugar_tr PF00083.19 EPS35029.1 - 3.9e-66 223.4 22.4 4.5e-66 223.2 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EPS35029.1 - 4.7e-08 32.1 29.8 4.7e-08 32.1 20.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1212 PF06738.7 EPS35029.1 - 3 7.2 15.2 3.6 7.0 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1212) Glyco_hydro_43 PF04616.9 EPS35030.1 - 8e-34 117.0 1.3 1.1e-33 116.5 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 RTA1 PF04479.8 EPS35032.1 - 4.5e-16 59.0 2.4 5.1e-16 58.8 1.7 1.0 1 0 0 1 1 1 1 RTA1 like protein DUF1418 PF07214.7 EPS35032.1 - 0.095 12.3 0.2 0.095 12.3 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1418) FAD_binding_1 PF00667.15 EPS35033.1 - 1.2e-23 83.7 0.0 1.5e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EPS35033.1 - 0.055 14.0 0.0 0.16 12.5 0.0 1.8 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain Cadherin_pro PF08758.6 EPS35033.1 - 0.066 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Cadherin prodomain like FAD_binding_3 PF01494.14 EPS35034.1 - 2.4e-19 69.5 0.5 6.2e-18 64.9 0.3 2.6 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 EPS35034.1 - 0.0028 16.5 0.0 0.25 10.1 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase NAD_binding_8 PF13450.1 EPS35034.1 - 0.019 14.9 0.0 0.044 13.8 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EPS35034.1 - 0.043 12.7 0.1 2.6 6.8 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 EPS35034.1 - 0.095 13.1 0.0 2.1 8.8 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase polyprenyl_synt PF00348.12 EPS35036.1 - 1.6e-53 181.2 0.0 1.9e-53 180.9 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.11 EPS35036.1 - 0.0058 15.8 0.0 0.011 14.9 0.0 1.4 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain adh_short PF00106.20 EPS35037.1 - 3.7e-24 85.5 2.6 6.4e-24 84.7 1.8 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EPS35037.1 - 5.2e-17 62.4 0.1 8.4e-17 61.7 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EPS35037.1 - 5.8e-07 29.3 2.6 3.6e-06 26.7 1.8 1.9 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EPS35037.1 - 0.00013 22.0 0.1 0.00018 21.5 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EPS35037.1 - 0.00048 19.8 1.0 0.0015 18.2 0.7 1.8 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DFP PF04127.10 EPS35037.1 - 0.0044 16.6 0.4 0.0061 16.1 0.3 1.2 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein ADH_zinc_N PF00107.21 EPS35037.1 - 0.013 15.0 0.2 0.023 14.2 0.1 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Epimerase PF01370.16 EPS35037.1 - 0.03 13.7 0.1 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DNA_processg_A PF02481.10 EPS35037.1 - 0.57 9.0 3.9 0.2 10.5 0.2 1.9 2 0 0 2 2 2 0 DNA recombination-mediator protein A p450 PF00067.17 EPS35038.1 - 1.4e-28 99.6 0.0 2.5e-28 98.8 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EPS35039.1 - 3.6e-27 95.0 0.0 4.7e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 UbiA PF01040.13 EPS35040.1 - 1.5e-29 103.0 17.6 4.8e-29 101.3 12.2 1.7 1 1 0 1 1 1 1 UbiA prenyltransferase family FA_desaturase PF00487.19 EPS35040.1 - 5.2 6.4 11.6 0.96 8.8 3.0 2.2 2 0 0 2 2 2 0 Fatty acid desaturase ketoacyl-synt PF00109.21 EPS35041.1 - 2.9e-73 246.4 0.0 5e-73 245.7 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EPS35041.1 - 1.7e-43 149.1 0.1 3.5e-43 148.1 0.1 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EPS35041.1 - 5.5e-31 106.8 0.2 1.4e-30 105.5 0.2 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 EPS35041.1 - 1e-29 103.6 0.0 1.8e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_23 PF13489.1 EPS35041.1 - 5.3e-09 35.9 0.0 1.2e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EPS35041.1 - 4.3e-07 30.3 0.0 1.3e-06 28.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EPS35041.1 - 1.3e-05 25.4 0.0 4.6e-05 23.6 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.1 EPS35041.1 - 9.3e-05 22.0 0.0 0.00033 20.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 EPS35041.1 - 0.00032 19.7 0.0 0.00075 18.5 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_12 PF08242.7 EPS35041.1 - 0.001 19.5 0.0 0.0055 17.1 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EPS35041.1 - 0.0057 15.7 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family KR PF08659.5 EPS35041.1 - 0.0077 15.9 0.2 0.036 13.7 0.0 2.2 2 0 0 2 2 2 1 KR domain AMP-binding PF00501.23 EPS35042.1 - 3.6e-67 226.5 0.0 4.6e-67 226.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EPS35042.1 - 1.1e-08 35.8 0.1 3.8e-08 34.1 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain QRPTase_C PF01729.14 EPS35042.1 - 0.05 13.1 0.0 0.2 11.1 0.0 1.9 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain p450 PF00067.17 EPS35043.1 - 8e-34 116.9 0.0 1e-33 116.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CHDNT PF08073.7 EPS35043.1 - 0.053 13.2 0.0 0.18 11.4 0.0 1.9 2 0 0 2 2 2 0 CHDNT (NUC034) domain PhyH PF05721.8 EPS35044.1 - 9.1e-28 97.7 0.0 1.2e-27 97.3 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.1 EPS35044.1 - 0.0024 18.3 0.0 0.11 12.9 0.0 2.4 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF1479 PF07350.7 EPS35044.1 - 0.1 11.0 0.0 0.18 10.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1479) p450 PF00067.17 EPS35045.1 - 6.5e-71 239.2 0.0 8.2e-71 238.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_71 PF03659.9 EPS35046.1 - 2.4e-151 503.6 7.1 3.8e-151 502.9 4.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 71